Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= NV021353
(698 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000E49AD8 Cluster: PREDICTED: similar to NAD-depend... 145 8e-34
UniRef50_Q8IXJ6 Cluster: NAD-dependent deacetylase sirtuin-2; n=... 141 1e-32
UniRef50_Q7ZVK3 Cluster: NAD-dependent deacetylase sirtuin-2; n=... 131 2e-29
UniRef50_Q54QE6 Cluster: Zn finger-containing protein; n=5; Euka... 127 3e-28
UniRef50_A7EC18 Cluster: Putative uncharacterized protein; n=1; ... 126 5e-28
UniRef50_Q298C7 Cluster: GA18650-PA; n=1; Drosophila pseudoobscu... 126 7e-28
UniRef50_A4QUX8 Cluster: Putative uncharacterized protein; n=1; ... 126 7e-28
UniRef50_A6RXY5 Cluster: Putative uncharacterized protein; n=2; ... 125 1e-27
UniRef50_Q7SCL4 Cluster: Putative uncharacterized protein NCU005... 124 2e-27
UniRef50_A2QFF9 Cluster: Complex: Sir2p is one of four Silent In... 124 2e-27
UniRef50_Q9NTG7 Cluster: NAD-dependent deacetylase sirtuin-3, mi... 121 1e-26
UniRef50_Q2H5A0 Cluster: Putative uncharacterized protein; n=1; ... 120 3e-26
UniRef50_Q5KDE0 Cluster: NAD-dependent histone deacetylase, puta... 119 8e-26
UniRef50_Q750H1 Cluster: AGL018Cp; n=1; Eremothecium gossypii|Re... 118 1e-25
UniRef50_A2F9H1 Cluster: Transcriptional regulator, Sir2 family ... 117 3e-25
UniRef50_A1DG07 Cluster: SIR2 family histone deacetylase, putati... 116 6e-25
UniRef50_Q07FY7 Cluster: Sirtuin (Silent mating type information... 116 7e-25
UniRef50_Q6FKU1 Cluster: Similar to sp|P53686 Saccharomyces cere... 115 1e-24
UniRef50_UPI0000499DEA Cluster: Sir2 family transcriptional regu... 115 1e-24
UniRef50_UPI00004997CB Cluster: Sir2 family transcriptional regu... 114 2e-24
UniRef50_Q011Q8 Cluster: NAD-dependent deacetylase SIRT2; n=2; O... 114 2e-24
UniRef50_A4QX96 Cluster: Putative uncharacterized protein; n=2; ... 114 2e-24
UniRef50_P53686 Cluster: NAD-dependent deacetylase HST2; n=4; Sa... 113 4e-24
UniRef50_UPI00005A356B Cluster: PREDICTED: similar to NAD-depend... 112 7e-24
UniRef50_Q9USN7 Cluster: Sir2 family histone deacetylase Hst2; n... 111 2e-23
UniRef50_Q4WFZ3 Cluster: SIR2 family histone deacetylase, putati... 111 2e-23
UniRef50_A1CD03 Cluster: SIR2 family histone deacetylase, putati... 109 5e-23
UniRef50_Q4S7H2 Cluster: Chromosome 13 SCAF14715, whole genome s... 109 6e-23
UniRef50_O94066 Cluster: Transcription regulatory protein; n=6; ... 107 2e-22
UniRef50_Q8R104 Cluster: NAD-dependent deacetylase sirtuin-3; n=... 107 2e-22
UniRef50_Q4P1X1 Cluster: Putative uncharacterized protein; n=1; ... 107 3e-22
UniRef50_A2GAR7 Cluster: Transcriptional regulator, Sir2 family ... 105 8e-22
UniRef50_Q1RL71 Cluster: Zinc finger protein; n=2; Ciona intesti... 105 1e-21
UniRef50_Q54P49 Cluster: Zn finger-containing protein; n=1; Dict... 102 1e-20
UniRef50_A7SX90 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 102 1e-20
UniRef50_A2F8N6 Cluster: Transcriptional regulator, Sir2 family ... 101 1e-20
UniRef50_Q5BVF7 Cluster: SJCHGC03105 protein; n=2; Schistosoma j... 101 2e-20
UniRef50_A7RLD5 Cluster: Predicted protein; n=1; Nematostella ve... 99 1e-19
UniRef50_UPI00006CA40C Cluster: transcriptional regulator, Sir2 ... 97 3e-19
UniRef50_A0C6J0 Cluster: Chromosome undetermined scaffold_152, w... 95 1e-18
UniRef50_Q96EB6 Cluster: NAD-dependent deacetylase sirtuin-1; n=... 95 2e-18
UniRef50_Q7QZ36 Cluster: GLP_464_21655_23334; n=1; Giardia lambl... 93 6e-18
UniRef50_UPI00015B57C0 Cluster: PREDICTED: similar to GA18743-PA... 92 1e-17
UniRef50_Q1RPU3 Cluster: Zinc finger protein; n=1; Ciona intesti... 91 2e-17
UniRef50_Q5KA61 Cluster: Histone deacetylase, putative; n=1; Fil... 91 2e-17
UniRef50_UPI000051AA14 Cluster: PREDICTED: similar to NAD-depend... 90 4e-17
UniRef50_Q54GV7 Cluster: NAD(+)-dependent deacetylase, silent in... 90 6e-17
UniRef50_A6XDL2 Cluster: Sirtuin 1; n=2; Schistosoma|Rep: Sirtui... 89 7e-17
UniRef50_Q21921 Cluster: NAD-dependent deacetylase SIR2 homolog;... 89 7e-17
UniRef50_UPI0001555321 Cluster: PREDICTED: similar to sirtuin (s... 89 1e-16
UniRef50_A4VDQ9 Cluster: Chromatin regulatory protein sir2; n=1;... 89 1e-16
UniRef50_Q7S6G9 Cluster: Putative uncharacterized protein NCU047... 88 2e-16
UniRef50_Q22ZC3 Cluster: Transcriptional regulator, Sir2 family ... 87 4e-16
UniRef50_Q4DP02 Cluster: Silent information regulator 2, putativ... 86 7e-16
UniRef50_Q7QZ37 Cluster: GLP_464_19573_21615; n=1; Giardia lambl... 86 9e-16
UniRef50_Q25337 Cluster: NAD-dependent deacetylase SIR2 homolog;... 85 2e-15
UniRef50_Q23E36 Cluster: Transcriptional regulator, Sir2 family ... 85 2e-15
UniRef50_Q0CR31 Cluster: NAD-dependent histone deacetylase SIR2;... 84 3e-15
UniRef50_UPI0000D55B5A Cluster: PREDICTED: similar to CG5216-PA;... 83 5e-15
UniRef50_O96505 Cluster: SIR2; n=4; Sophophora|Rep: SIR2 - Droso... 82 1e-14
UniRef50_A2Q9C4 Cluster: Contig An01c0250, complete genome; n=18... 82 1e-14
UniRef50_A0C2R2 Cluster: Chromosome undetermined scaffold_145, w... 79 1e-13
UniRef50_Q4PG00 Cluster: Putative uncharacterized protein; n=1; ... 77 4e-13
UniRef50_A7EMW8 Cluster: Putative uncharacterized protein; n=1; ... 75 2e-12
UniRef50_A2F8E1 Cluster: Transcriptional regulator, Sir2 family ... 73 9e-12
UniRef50_A7TQE2 Cluster: Putative uncharacterized protein; n=1; ... 72 2e-11
UniRef50_Q0UNC9 Cluster: Putative uncharacterized protein; n=1; ... 71 3e-11
UniRef50_Q6BPH5 Cluster: Debaryomyces hansenii chromosome E of s... 70 5e-11
UniRef50_O94640 Cluster: NAD-dependent histone deacetylase sir2;... 70 5e-11
UniRef50_O59923 Cluster: NAD-dependent histone deacetylase SIR2;... 69 1e-10
UniRef50_A6RRE3 Cluster: Putative uncharacterized protein; n=1; ... 68 2e-10
UniRef50_A5DJ74 Cluster: Putative uncharacterized protein; n=1; ... 66 6e-10
UniRef50_A3LN35 Cluster: NAD-dependent histone deacetylase SIR2;... 66 8e-10
UniRef50_P06700 Cluster: NAD-dependent histone deacetylase SIR2;... 65 2e-09
UniRef50_Q3A6W7 Cluster: NAD-dependent protein deacetylases, SIR... 64 3e-09
UniRef50_Q875P9 Cluster: HST1; n=1; Lachancea kluyveri|Rep: HST1... 63 6e-09
UniRef50_Q5AQ47 Cluster: Potential Sir2 family histone deacetyla... 63 7e-09
UniRef50_A5DSX8 Cluster: NAD-dependent histone deacetylase SIR2;... 63 7e-09
UniRef50_A5DNV7 Cluster: Putative uncharacterized protein; n=1; ... 62 1e-08
UniRef50_Q6C219 Cluster: Yarrowia lipolytica chromosome F of str... 62 2e-08
UniRef50_Q9WYW0 Cluster: NAD-dependent deacetylase; n=4; Thermot... 61 3e-08
UniRef50_A6P1S7 Cluster: Putative uncharacterized protein; n=2; ... 59 1e-07
UniRef50_Q0AY57 Cluster: Regulatory protein, sir2 family; n=1; S... 58 3e-07
UniRef50_A4M603 Cluster: Silent information regulator protein Si... 54 3e-06
UniRef50_A2DKY5 Cluster: Transcriptional regulator, Sir2 family ... 54 3e-06
UniRef50_A6LP94 Cluster: Silent information regulator protein Si... 54 4e-06
UniRef50_A4J646 Cluster: Silent information regulator protein Si... 53 8e-06
UniRef50_A7HL19 Cluster: Silent information regulator protein Si... 52 2e-05
UniRef50_Q839C6 Cluster: NAD-dependent deacetylase; n=14; Bacill... 51 2e-05
UniRef50_Q8R984 Cluster: NAD-dependent deacetylase 2; n=1; Therm... 51 2e-05
UniRef50_Q6BPA4 Cluster: Debaryomyces hansenii chromosome E of s... 50 4e-05
UniRef50_Q97MB4 Cluster: NAD-dependent deacetylase; n=7; Bacteri... 50 4e-05
UniRef50_Q899G3 Cluster: NAD-dependent deacetylase; n=19; cellul... 50 5e-05
UniRef50_A6DC77 Cluster: Silent information regulator protein Si... 50 7e-05
UniRef50_Q5KPC9 Cluster: Hst3 protein, putative; n=2; Filobasidi... 50 7e-05
UniRef50_Q54LF0 Cluster: Ankyrin repeat-containing protein; n=1;... 49 1e-04
UniRef50_Q4WT50 Cluster: SIR2 family histone deacetylase (Hst4),... 49 1e-04
UniRef50_UPI000049979A Cluster: Sir2 family transcriptional regu... 48 2e-04
UniRef50_Q2HG51 Cluster: Putative uncharacterized protein; n=2; ... 48 2e-04
UniRef50_Q5L014 Cluster: NAD-dependent deacetylase 1; n=7; Bacil... 48 2e-04
UniRef50_A6RSV6 Cluster: Putative uncharacterized protein; n=2; ... 47 4e-04
UniRef50_Q73KE1 Cluster: NAD-dependent deacetylase; n=1; Trepone... 47 4e-04
UniRef50_Q0UMU7 Cluster: Putative uncharacterized protein; n=1; ... 46 7e-04
UniRef50_Q8ZU41 Cluster: NAD-dependent deacetylase 1; n=3; Pyrob... 46 9e-04
UniRef50_Q8F3Z6 Cluster: NAD-dependent deacetylase; n=4; Leptosp... 46 0.001
UniRef50_Q2GZ88 Cluster: Putative uncharacterized protein; n=1; ... 45 0.002
UniRef50_Q7S386 Cluster: Putative uncharacterized protein NCU048... 45 0.002
UniRef50_O07595 Cluster: NAD-dependent deacetylase; n=3; Bacillu... 45 0.002
UniRef50_A3LRA1 Cluster: Transcriptional regulatory protein; n=2... 44 0.003
UniRef50_Q81NT6 Cluster: NAD-dependent deacetylase; n=11; Bacill... 44 0.003
UniRef50_Q5KZE8 Cluster: NAD-dependent deacetylase 2; n=3; Bacte... 44 0.003
UniRef50_P53687 Cluster: NAD-dependent histone deacetylase HST3;... 44 0.003
UniRef50_A1CTI6 Cluster: SIR2 family histone deacetylase, putati... 44 0.004
UniRef50_Q8CNF4 Cluster: NAD-dependent deacetylase; n=17; Staphy... 44 0.004
UniRef50_UPI000023F1DF Cluster: hypothetical protein FG02466.1; ... 44 0.005
UniRef50_Q1RPU9 Cluster: Zinc finger protein; n=1; Ciona intesti... 44 0.005
UniRef50_Q8SSB6 Cluster: SIR2-LIKE PROTEIN INVOLVED IN TELOMERIC... 44 0.005
UniRef50_Q6CAJ8 Cluster: Similar to sp|P53687 Saccharomyces cere... 44 0.005
UniRef50_UPI000023E2DA Cluster: hypothetical protein FG00460.1; ... 43 0.006
UniRef50_A7B9E8 Cluster: Putative uncharacterized protein; n=1; ... 43 0.006
UniRef50_A6R1B0 Cluster: Predicted protein; n=2; Onygenales|Rep:... 43 0.006
UniRef50_Q6CB00 Cluster: Similarities with tr|Q9UR39 Schizosacch... 43 0.008
UniRef50_A5DW75 Cluster: Putative uncharacterized protein; n=1; ... 43 0.008
UniRef50_Q9Y6E7 Cluster: NAD-dependent deacetylase sirtuin-4; n=... 43 0.008
UniRef50_Q9UR39 Cluster: NAD-dependent deacetylase hst4; n=1; Sc... 43 0.008
UniRef50_Q03ZB1 Cluster: NAD-dependent protein deacetylase, SIR2... 42 0.011
UniRef50_A5WD15 Cluster: Silent information regulator protein Si... 42 0.011
UniRef50_A5AF92 Cluster: Putative uncharacterized protein; n=1; ... 42 0.011
UniRef50_A0LG97 Cluster: Silent information regulator protein Si... 42 0.015
UniRef50_Q974M6 Cluster: NAD-dependent deacetylase; n=8; Thermop... 42 0.015
UniRef50_UPI00006CB0CC Cluster: transcriptional regulator, Sir2 ... 42 0.019
UniRef50_UPI000049971A Cluster: Sir2 family transcriptional regu... 42 0.019
UniRef50_A5UYK2 Cluster: Silent information regulator protein Si... 42 0.019
UniRef50_A4RMS1 Cluster: Putative uncharacterized protein; n=2; ... 42 0.019
UniRef50_Q8R216 Cluster: NAD-dependent deacetylase sirtuin-4; n=... 42 0.019
UniRef50_Q95Q89 Cluster: Yeast sir related protein 2.4; n=2; Cae... 41 0.025
UniRef50_Q6BVM7 Cluster: Similar to CA4170|IPF7784 Candida albic... 41 0.025
UniRef50_Q2KH01 Cluster: Putative uncharacterized protein; n=2; ... 41 0.025
UniRef50_A1ZHW6 Cluster: NAD-dependent deacetylase; n=2; Microsc... 41 0.034
UniRef50_Q9FE17 Cluster: Sir2-like protein; n=9; Magnoliophyta|R... 41 0.034
UniRef50_Q7SB01 Cluster: Putative uncharacterized protein NCU076... 41 0.034
UniRef50_Q8REC3 Cluster: NAD-dependent deacetylase; n=3; Fusobac... 41 0.034
UniRef50_A0NQ49 Cluster: Silent information regulator protein Si... 40 0.044
UniRef50_Q7PS76 Cluster: ENSANGP00000025231; n=1; Anopheles gamb... 40 0.044
UniRef50_A2DKF0 Cluster: Transcriptional regulator, Sir2 family ... 40 0.044
UniRef50_Q6C8C7 Cluster: Similar to DEHA0C01507g Debaryomyces ha... 40 0.044
UniRef50_A2QWZ2 Cluster: Function: human SIRT5 belongs to the Si... 40 0.044
UniRef50_Q1MT39 Cluster: Novel protein similar to vertebratesirt... 40 0.059
UniRef50_Q3E2I1 Cluster: Silent information regulator protein Si... 40 0.059
UniRef50_Q2YZT2 Cluster: Putative uncharacterized protein; n=1; ... 40 0.059
UniRef50_Q8IRR5 Cluster: CG3187-PC, isoform C; n=4; Diptera|Rep:... 40 0.059
UniRef50_Q7R0R8 Cluster: GLP_79_6121_4343; n=1; Giardia lamblia ... 40 0.059
UniRef50_Q12Y78 Cluster: Silent information regulator protein Si... 40 0.059
UniRef50_UPI0000519F58 Cluster: PREDICTED: similar to Sirt4 CG31... 40 0.078
UniRef50_Q9VH08 Cluster: CG6284-PA; n=9; Eumetazoa|Rep: CG6284-P... 40 0.078
UniRef50_A7AWG1 Cluster: Transcriptional regulator, Sir2 family ... 40 0.078
UniRef50_Q88BY5 Cluster: NAD-dependent deacetylase; n=9; Bacteri... 40 0.078
UniRef50_P53688 Cluster: NAD-dependent histone deacetylase HST4;... 39 0.10
UniRef50_UPI00015B4FA0 Cluster: PREDICTED: similar to chromatin ... 39 0.14
UniRef50_Q5KG84 Cluster: Hst4 protein, putative; n=2; Filobasidi... 39 0.14
UniRef50_Q9RYD4 Cluster: NAD-dependent deacetylase; n=4; Deinoco... 39 0.14
UniRef50_A5USR3 Cluster: Silent information regulator protein Si... 38 0.18
UniRef50_A3ZMQ7 Cluster: Sir2 family, possible ADP ribosyltransf... 38 0.18
UniRef50_Q7JMD3 Cluster: Putative uncharacterized protein sir-2.... 38 0.18
UniRef50_Q6CQA7 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 38 0.18
UniRef50_Q9CBW6 Cluster: NAD-dependent deacetylase; n=14; Mycoba... 38 0.18
UniRef50_Q88ZA0 Cluster: NAD-dependent deacetylase; n=4; Lactoba... 38 0.18
UniRef50_Q89LY4 Cluster: NAD-dependent deacetylase 1; n=12; Prot... 38 0.18
UniRef50_A1ZPG8 Cluster: NAD-dependent deacetylase; n=1; Microsc... 38 0.24
UniRef50_Q2LSF2 Cluster: Sir2 family of NAD+-dependent deacetyla... 38 0.31
UniRef50_Q046W9 Cluster: NAD-dependent protein deacetylase, SIR2... 38 0.31
UniRef50_A1FG80 Cluster: Silent information regulator protein Si... 38 0.31
UniRef50_Q8IKW2 Cluster: Putative uncharacterized protein; n=1; ... 38 0.31
UniRef50_Q1EP52 Cluster: Transcriptional regulator Sir2 family p... 37 0.41
UniRef50_Q7RP35 Cluster: Sir2-like protein; n=5; Plasmodium (Vin... 37 0.41
UniRef50_A7DQD6 Cluster: Silent information regulator protein Si... 37 0.41
UniRef50_Q67KQ0 Cluster: NAD-dependent deacetylase; n=1; Symbiob... 37 0.41
UniRef50_A0PU12 Cluster: Sir2-like regulatory protein; n=1; Myco... 37 0.55
UniRef50_A7SK95 Cluster: Predicted protein; n=1; Nematostella ve... 37 0.55
UniRef50_Q9NRC8 Cluster: NAD-dependent deacetylase sirtuin-7; n=... 37 0.55
UniRef50_Q8Y015 Cluster: NAD-dependent deacetylase; n=11; Bacter... 37 0.55
UniRef50_Q8FRV5 Cluster: NAD-dependent deacetylase 2; n=9; Coryn... 37 0.55
UniRef50_Q8FUC8 Cluster: NAD-dependent deacetylase 1; n=6; Coryn... 37 0.55
UniRef50_Q5YR82 Cluster: Putative Sir2 family regulator; n=1; No... 36 0.72
UniRef50_Q3F1F4 Cluster: SIR2 family protein; n=1; Bacillus thur... 36 0.72
UniRef50_Q9FY91 Cluster: SIR2-family protein; n=12; Magnoliophyt... 36 0.72
UniRef50_Q4QB33 Cluster: Sir2-family protein-like protein; n=4; ... 36 0.72
UniRef50_Q6C8V5 Cluster: Similar to tr|Q9FY91 Arabidopsis thalia... 36 0.72
UniRef50_Q9NXA8 Cluster: NAD-dependent deacetylase sirtuin-5; n=... 36 0.72
UniRef50_A7RMK8 Cluster: Predicted protein; n=5; Eumetazoa|Rep: ... 36 0.96
UniRef50_A2DZ29 Cluster: Transcriptional regulator, Sir2 family ... 36 0.96
UniRef50_Q3V7G9 Cluster: Putative cobalamin biosynthetic protein... 36 1.3
UniRef50_A6WG46 Cluster: Silent information regulator protein Si... 36 1.3
UniRef50_A1ZZG3 Cluster: NAD-dependent deacetylase; n=35; Bacter... 36 1.3
UniRef50_A5K3P4 Cluster: Putative uncharacterized protein; n=1; ... 36 1.3
UniRef50_Q7S223 Cluster: Putative uncharacterized protein NCU059... 36 1.3
UniRef50_Q607X6 Cluster: NAD-dependent deacetylase; n=1; Methylo... 36 1.3
UniRef50_Q8ZT00 Cluster: NAD-dependent deacetylase 2; n=2; cellu... 36 1.3
UniRef50_UPI0000D573CE Cluster: PREDICTED: similar to CG11305-PA... 35 1.7
UniRef50_A4UCE7 Cluster: Putative uncharacterized protein; n=1; ... 35 1.7
UniRef50_Q8U1Q1 Cluster: NAD-dependent deacetylase; n=19; cellul... 35 1.7
UniRef50_Q8CJM9 Cluster: NAD-dependent deacetylase 2; n=3; Actin... 35 1.7
UniRef50_Q8N6T7-2 Cluster: Isoform 2 of Q8N6T7 ; n=5; Catarrhini... 35 2.2
UniRef50_Q4RA56 Cluster: Chromosome undetermined SCAF24448, whol... 35 2.2
UniRef50_A6G0H3 Cluster: Silent information regulator protein Si... 35 2.2
UniRef50_Q23A43 Cluster: Transcriptional regulator, Sir2 family ... 35 2.2
UniRef50_Q8N6T7 Cluster: Mono-ADP-ribosyltransferase sirtuin-6; ... 35 2.2
UniRef50_Q1D9X2 Cluster: Sir2 family protein; n=1; Myxococcus xa... 34 2.9
UniRef50_A6PTK3 Cluster: Silent information regulator protein Si... 34 2.9
UniRef50_A0JXS0 Cluster: Silent information regulator protein Si... 34 2.9
UniRef50_Q9RL35 Cluster: NAD-dependent deacetylase 1; n=8; Actin... 34 2.9
UniRef50_A1I9S7 Cluster: NAD-dependent deacetylase; n=1; Candida... 34 3.9
UniRef50_A0YUL1 Cluster: Peptidase C14, caspase catalytic subuni... 34 3.9
UniRef50_Q4P2A5 Cluster: Putative uncharacterized protein; n=1; ... 34 3.9
UniRef50_Q885X7 Cluster: NAD-dependent deacetylase 2; n=4; Pseud... 34 3.9
UniRef50_Q9I4E1 Cluster: NAD-dependent deacetylase 2; n=6; Pseud... 34 3.9
UniRef50_UPI0000D578DC Cluster: PREDICTED: similar to sirtuin 5 ... 33 5.1
UniRef50_Q8N6T7-3 Cluster: Isoform 3 of Q8N6T7 ; n=2; Catarrhini... 33 5.1
UniRef50_A7H7B6 Cluster: Silent information regulator protein Si... 33 5.1
UniRef50_A6FYM4 Cluster: Sir2 family protein; n=1; Plesiocystis ... 33 5.1
UniRef50_A1HLU5 Cluster: Silent information regulator protein Si... 33 5.1
UniRef50_Q9VAQ1 Cluster: CG11305-PA; n=8; Coelomata|Rep: CG11305... 33 5.1
UniRef50_Q5CYK0 Cluster: Bacterial-like Sir2 family protein; n=2... 33 5.1
UniRef50_Q6ZMU6 Cluster: CDNA FLJ16662 fis, clone TESTI4046240, ... 33 5.1
UniRef50_A6RLG6 Cluster: Putative uncharacterized protein; n=2; ... 33 5.1
UniRef50_A4RCT8 Cluster: Putative uncharacterized protein; n=3; ... 33 5.1
UniRef50_A6Q178 Cluster: Transcription regulator, Sir2 family; n... 33 6.7
UniRef50_Q175I4 Cluster: Chromatin regulatory protein sir2; n=3;... 33 6.7
UniRef50_Q6CHN4 Cluster: Similar to tr|Q96QF7 Homo sapiens NAAR1... 33 6.7
UniRef50_Q882K4 Cluster: NAD-dependent deacetylase 3; n=5; Pseud... 33 6.7
UniRef50_UPI000050FCF4 Cluster: COG0846: NAD-dependent protein d... 33 8.9
UniRef50_A6TNA0 Cluster: Silent information regulator protein Si... 33 8.9
UniRef50_Q55DB0 Cluster: NAD(+)-dependent deacetylase, silent in... 33 8.9
UniRef50_Q4UH74 Cluster: Sir2-like histone deacetylase, putative... 33 8.9
UniRef50_Q2U9Y7 Cluster: Sirtuin 4 and related class II sirtuins... 33 8.9
UniRef50_A4RNA8 Cluster: Putative uncharacterized protein; n=1; ... 33 8.9
UniRef50_Q9I4L0 Cluster: NAD-dependent deacetylase 1; n=10; Bact... 33 8.9
>UniRef50_UPI0000E49AD8 Cluster: PREDICTED: similar to NAD-dependent
deacetylase sirtuin 2 homolog; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to NAD-dependent
deacetylase sirtuin 2 homolog - Strongylocentrotus
purpuratus
Length = 400
Score = 145 bits (352), Expect = 8e-34
Identities = 72/131 (54%), Positives = 86/131 (65%), Gaps = 1/131 (0%)
Frame = +2
Query: 257 GIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFR 436
GI +IK +CKK+I +SGAGISTSAGIPDFR+P TGLY NLQKY LP PQAIFEI FF+
Sbjct: 63 GIADFIKEGKCKKVIVMSGAGISTSAGIPDFRTPGTGLYDNLQKYNLPNPQAIFEIGFFK 122
Query: 437 QNPKPFFTLAKELFPGSFKPTISHIS*DFYMRKGSYYVIIHKTLTH*SEEPAFPKKN*SK 616
QNP+PFFTL+KELFPG+F PT SH KG + + P + +
Sbjct: 123 QNPEPFFTLSKELFPGAFYPTPSHFFIHLLHEKGILLRHYTQNIDGLDRMAGVPDELIME 182
Query: 617 -HTEFYTSHCL 646
H F+T HCL
Sbjct: 183 AHGSFHTGHCL 193
>UniRef50_Q8IXJ6 Cluster: NAD-dependent deacetylase sirtuin-2; n=31;
Coelomata|Rep: NAD-dependent deacetylase sirtuin-2 -
Homo sapiens (Human)
Length = 389
Score = 141 bits (342), Expect = 1e-32
Identities = 66/131 (50%), Positives = 89/131 (67%), Gaps = 1/131 (0%)
Frame = +2
Query: 257 GIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFR 436
G+ R+++S+RC+++I L GAGISTSAGIPDFRSP TGLY NL+KY LP P+AIFEI++F+
Sbjct: 66 GVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFK 125
Query: 437 QNPKPFFTLAKELFPGSFKPTISHIS*DFYMRKGSYYVIIHKTLTH*SEEPAFPKKN-*S 613
++P+PFF LAKEL+PG FKPTI H KG + + +++
Sbjct: 126 KHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVE 185
Query: 614 KHTEFYTSHCL 646
H FYTSHC+
Sbjct: 186 AHGTFYTSHCV 196
>UniRef50_Q7ZVK3 Cluster: NAD-dependent deacetylase sirtuin-2; n=12;
Coelomata|Rep: NAD-dependent deacetylase sirtuin-2 -
Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 379
Score = 131 bits (316), Expect = 2e-29
Identities = 63/130 (48%), Positives = 84/130 (64%), Gaps = 1/130 (0%)
Frame = +2
Query: 260 IVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQ 439
+ R+I S +CK II + GAGISTSAGIPDFRSP TGLY NLQKY LP P+AIF+I++F++
Sbjct: 65 VARYILSGKCKNIICMVGAGISTSAGIPDFRSPGTGLYANLQKYNLPYPEAIFQIDYFKK 124
Query: 440 NPKPFFTLAKELFPGSFKPTISHIS*DFYMRKGSYYVIIHKTLTH*SEEPAFPKKN-*SK 616
+P+PFF LA+EL+PG FKPT+ H KG + + ++
Sbjct: 125 HPEPFFALARELYPGQFKPTVYHYFIKMLKDKGLLRRCYSQNIDTLERVAGLEGEDLIEA 184
Query: 617 HTEFYTSHCL 646
H F+TSHC+
Sbjct: 185 HGTFHTSHCV 194
>UniRef50_Q54QE6 Cluster: Zn finger-containing protein; n=5;
Eukaryota|Rep: Zn finger-containing protein -
Dictyostelium discoideum AX4
Length = 512
Score = 127 bits (306), Expect = 3e-28
Identities = 62/130 (47%), Positives = 80/130 (61%), Gaps = 1/130 (0%)
Frame = +2
Query: 260 IVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQ 439
I ++I S +CK II ++GAGIS +AGIPDFRSP+TGLY L KY+LP +AIF+I +F++
Sbjct: 241 IAKYINSAKCKNIIVMTGAGISVAAGIPDFRSPKTGLYEKLDKYDLPYREAIFDIEYFKK 300
Query: 440 NPKPFFTLAKELFPGSFKPTISHIS*DFYMRKGSYYVIIHKTLTH*SEEPAFP-KKN*SK 616
NPKPF+ L+KELFPGSF PT H KG + + P K
Sbjct: 301 NPKPFYVLSKELFPGSFNPTTVHYFIKLLSDKGLLLRNFTQNIDTLERIAGIPANKLVEA 360
Query: 617 HTEFYTSHCL 646
H F TSHC+
Sbjct: 361 HGSFATSHCV 370
>UniRef50_A7EC18 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 446
Score = 126 bits (304), Expect = 5e-28
Identities = 61/144 (42%), Positives = 87/144 (60%), Gaps = 1/144 (0%)
Frame = +2
Query: 257 GIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFR 436
G+ +IK+ + K I+ L+GAGISTSAGIPDFRSPETG+Y NL + +LP +A+F+I+FFR
Sbjct: 26 GVAEFIKNGQAKNIVVLTGAGISTSAGIPDFRSPETGIYANLAELDLPYAEAVFDIDFFR 85
Query: 437 QNPKPFFTLAKELFPGSFKPTISHIS*DFYMRKGSYYVIIHKTLTH*SEEPAF-PKKN*S 613
+NP PF+ LAKEL+PG F PTISH +KG ++ + + +K
Sbjct: 86 ENPAPFYVLAKELYPGQFYPTISHAFVALIEKKGLLRMLFTQNIDCLERRAGVSSEKVIE 145
Query: 614 KHTEFYTSHCLGLPQGIPTGVCQR 685
H F T C+ P + ++
Sbjct: 146 AHGSFATQRCIDCKTEYPDDMMKK 169
>UniRef50_Q298C7 Cluster: GA18650-PA; n=1; Drosophila
pseudoobscura|Rep: GA18650-PA - Drosophila pseudoobscura
(Fruit fly)
Length = 381
Score = 126 bits (303), Expect = 7e-28
Identities = 65/123 (52%), Positives = 81/123 (65%), Gaps = 3/123 (2%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAK 469
KKIIT+ GAGISTSAGIPDFRSP +GLY NL KY+LP P AIFE+ +F++ P PFF LAK
Sbjct: 76 KKIITMVGAGISTSAGIPDFRSPGSGLYDNLAKYKLPYPTAIFELGYFKKKPAPFFALAK 135
Query: 470 ELFPGSFKPTISHIS*DFYMRKG---SYYVIIHKTLTH*SEEPAFPKKN*SKHTEFYTSH 640
EL+PGSF+PT +H KG +Y TL + P +K H F+T+H
Sbjct: 136 ELYPGSFEPTTAHYFIRLLHEKGLLLRHYTQNIDTLDRLAGIP--DEKLIEAHGSFHTNH 193
Query: 641 CLG 649
C+G
Sbjct: 194 CIG 196
>UniRef50_A4QUX8 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 460
Score = 126 bits (303), Expect = 7e-28
Identities = 60/133 (45%), Positives = 85/133 (63%), Gaps = 1/133 (0%)
Frame = +2
Query: 272 IKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKP 451
IKS + K+I ++GAGIST+AGIPDFRSP TGLY NL++ +LP+P+A+F+I+FFR P+P
Sbjct: 34 IKSGKVKRITVMTGAGISTAAGIPDFRSPGTGLYSNLERLKLPEPEAVFDISFFRDRPEP 93
Query: 452 FFTLAKELFPGSFKPTISHIS*DFYMRKGSYYVIIHKTLTH*SEEPAFP-KKN*SKHTEF 628
F+ LAKEL+PG F+PTISH +KG + + + + P +K H F
Sbjct: 94 FYVLAKELYPGKFQPTISHAFIALLSKKGLLQMNFTQNIDCLERQAGVPGEKVIEAHGSF 153
Query: 629 YTSHCLGLPQGIP 667
T C+ + P
Sbjct: 154 ATQSCIECKELFP 166
>UniRef50_A6RXY5 Cluster: Putative uncharacterized protein; n=2;
Pezizomycotina|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 446
Score = 125 bits (301), Expect = 1e-27
Identities = 60/144 (41%), Positives = 86/144 (59%), Gaps = 1/144 (0%)
Frame = +2
Query: 257 GIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFR 436
G+ +IKS + K I+ ++GAGISTSAGIPDFRSPETG+Y NL + LP +A+F+I+FFR
Sbjct: 26 GVADFIKSGKAKNIVVMTGAGISTSAGIPDFRSPETGIYANLAELNLPYAEAVFDIDFFR 85
Query: 437 QNPKPFFTLAKELFPGSFKPTISHIS*DFYMRKGSYYVIIHKTLTH*SEEPAF-PKKN*S 613
+NP PF+ LAKEL+PG F PT+SH +KG ++ + + +K
Sbjct: 86 ENPAPFYVLAKELYPGQFYPTVSHAFVALIEKKGLLRMLFTQNIDCLERRAGVSSEKVIE 145
Query: 614 KHTEFYTSHCLGLPQGIPTGVCQR 685
H F T C+ P + ++
Sbjct: 146 AHGSFATQRCIDCKTEYPDDMMKK 169
>UniRef50_Q7SCL4 Cluster: Putative uncharacterized protein NCU00523.1;
n=2; Pezizomycotina|Rep: Putative uncharacterized protein
NCU00523.1 - Neurospora crassa
Length = 1220
Score = 124 bits (300), Expect = 2e-27
Identities = 53/103 (51%), Positives = 74/103 (71%)
Frame = +2
Query: 260 IVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQ 439
+ +IKS + +K++ L+GAGIST+AGIPDFRSPETGLY NL EL +P+ +F + FF++
Sbjct: 868 VADYIKSGKARKVVVLTGAGISTAAGIPDFRSPETGLYANLAALELEEPEDVFSLPFFKE 927
Query: 440 NPKPFFTLAKELFPGSFKPTISHIS*DFYMRKGSYYVIIHKTL 568
NPKPF+ LAK+L+PG F PTISH+ KG Y + + +
Sbjct: 928 NPKPFYVLAKDLYPGKFHPTISHVFISLLATKGLLYQLFTQNI 970
Score = 53.2 bits (122), Expect = 6e-06
Identities = 28/66 (42%), Positives = 38/66 (57%)
Frame = +1
Query: 427 FLQAKSQTFLHISKGIISRKL*AYNFTYFIRLLHEKGLLLRHYTQNIDTLERGAGIPEEK 606
F + + F ++K + K FI LL KGLL + +TQNID LER AG+P +
Sbjct: 924 FFKENPKPFYVLAKDLYPGKFHPTISHVFISLLATKGLLYQLFTQNIDCLERAAGVPADL 983
Query: 607 LVEAHG 624
+VEAHG
Sbjct: 984 IVEAHG 989
>UniRef50_A2QFF9 Cluster: Complex: Sir2p is one of four Silent
Information Regulator genes in yeast. Sir2p; n=6;
Pezizomycotina|Rep: Complex: Sir2p is one of four Silent
Information Regulator genes in yeast. Sir2p -
Aspergillus niger
Length = 378
Score = 124 bits (299), Expect = 2e-27
Identities = 59/143 (41%), Positives = 84/143 (58%), Gaps = 1/143 (0%)
Frame = +2
Query: 260 IVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQ 439
I +++K K+++ + GAGISTSAGIPDFRSP+TG+Y NL +LP P+A+F+I+FFRQ
Sbjct: 26 IAKYVKQKPVKRVVVMVGAGISTSAGIPDFRSPDTGIYSNLAHLDLPDPEAVFDISFFRQ 85
Query: 440 NPKPFFTLAKELFPGSFKPTISHIS*DFYMRKGSYYVIIHKTLTH*SEEPAFP-KKN*SK 616
NP+PF+ LA+EL PG F+PTI+H KG + + P K
Sbjct: 86 NPRPFYALARELAPGQFRPTIAHSFIKLLYDKGMLLKHFSQNIDCLERLAGVPGDKIVEA 145
Query: 617 HTEFYTSHCLGLPQGIPTGVCQR 685
H F T HC+ P + ++
Sbjct: 146 HGSFATQHCIDCKAEYPEDLMKK 168
>UniRef50_Q9NTG7 Cluster: NAD-dependent deacetylase sirtuin-3,
mitochondrial precursor; n=22; Euteleostomi|Rep:
NAD-dependent deacetylase sirtuin-3, mitochondrial
precursor - Homo sapiens (Human)
Length = 399
Score = 121 bits (292), Expect = 1e-26
Identities = 49/83 (59%), Positives = 68/83 (81%)
Frame = +2
Query: 260 IVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQ 439
+ I++ C++++ + GAGIST +GIPDFRSP +GLY NLQ+Y+LP P+AIFE+ FF
Sbjct: 128 VAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFH 187
Query: 440 NPKPFFTLAKELFPGSFKPTISH 508
NPKPFFTLAKEL+PG++KP ++H
Sbjct: 188 NPKPFFTLAKELYPGNYKPNVTH 210
Score = 67.7 bits (158), Expect = 3e-10
Identities = 31/39 (79%), Positives = 34/39 (87%)
Frame = +1
Query: 508 YFIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
YF+RLLH+KGLLLR YTQNID LER +GIP KLVEAHG
Sbjct: 211 YFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHG 249
>UniRef50_Q2H5A0 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 387
Score = 120 bits (290), Expect = 3e-26
Identities = 51/104 (49%), Positives = 79/104 (75%), Gaps = 1/104 (0%)
Frame = +2
Query: 260 IVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQ 439
+ +IKS + ++I+ ++GAGIST+AGIPDFRSP TGLY NL LP+P+A+F+++FFRQ
Sbjct: 25 VADFIKSGQARRIVVMTGAGISTAAGIPDFRSPTTGLYANLSALNLPEPEAVFDLSFFRQ 84
Query: 440 NPKPFFTLAKELFPGS-FKPTISHIS*DFYMRKGSYYVIIHKTL 568
NP+PF+ LA+EL+PG+ ++PTISH R+G +++ + +
Sbjct: 85 NPQPFYVLARELYPGARYRPTISHAFLALLARRGLLHMLFTQNI 128
Score = 50.8 bits (116), Expect = 3e-05
Identities = 22/38 (57%), Positives = 29/38 (76%)
Frame = +1
Query: 511 FIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
F+ LL +GLL +TQNID LER AG+P +++VEAHG
Sbjct: 110 FLALLARRGLLHMLFTQNIDCLERAAGVPADRIVEAHG 147
>UniRef50_Q5KDE0 Cluster: NAD-dependent histone deacetylase,
putative; n=2; Filobasidiella neoformans|Rep:
NAD-dependent histone deacetylase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 413
Score = 119 bits (286), Expect = 8e-26
Identities = 60/127 (47%), Positives = 77/127 (60%), Gaps = 1/127 (0%)
Frame = +2
Query: 269 WIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPK 448
+IKS K +I L GAGISTSAGIPDFRSP TGLYHNLQ ELP P+A+FE+ FF++ P+
Sbjct: 66 FIKSGNAKDVIFLLGAGISTSAGIPDFRSPSTGLYHNLQALELPFPEAVFELGFFQRRPE 125
Query: 449 PFFTLAKELFPGSFKPTISHIS*DFYMRKGSYYVIIHKTLTH*SEEPAFPKK-N*SKHTE 625
PF+TLAKE++PG PT +H + R + + + P H
Sbjct: 126 PFWTLAKEIYPGRHFPTPTHYLLQLFNRHNLLKRVFTQNIDTLETLAGLPPHLIVEAHGS 185
Query: 626 FYTSHCL 646
F T+HCL
Sbjct: 186 FATAHCL 192
>UniRef50_Q750H1 Cluster: AGL018Cp; n=1; Eremothecium gossypii|Rep:
AGL018Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 340
Score = 118 bits (285), Expect = 1e-25
Identities = 55/138 (39%), Positives = 83/138 (60%), Gaps = 1/138 (0%)
Frame = +2
Query: 260 IVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQ 439
+ ++IK+ K++ L GAGISTS GIPDFRSP TGLYHNL K++LP +A+F I++F++
Sbjct: 12 VAKYIKNHPKAKVVFLVGAGISTSCGIPDFRSPNTGLYHNLSKFKLPYAEAVFAIDYFQR 71
Query: 440 NPKPFFTLAKELFPGSFKPTISHIS*DFYMRKGSYYVIIHKTLTH*SEEPAFPKKN-*SK 616
+PKPF+TLA+E++PG + P+ H + KG + + + E
Sbjct: 72 DPKPFYTLAREMYPGKYIPSRFHYLMKLFESKGYLKAVYTQNIDTLEREAGIAADYIIEA 131
Query: 617 HTEFYTSHCLGLPQGIPT 670
H F T+HC+ + PT
Sbjct: 132 HGSFATNHCIDCDKTFPT 149
>UniRef50_A2F9H1 Cluster: Transcriptional regulator, Sir2 family
protein; n=2; Trichomonas vaginalis|Rep: Transcriptional
regulator, Sir2 family protein - Trichomonas vaginalis
G3
Length = 304
Score = 117 bits (281), Expect = 3e-25
Identities = 58/130 (44%), Positives = 77/130 (59%), Gaps = 1/130 (0%)
Frame = +2
Query: 257 GIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFR 436
G+V +IKS + KKII L+GAGIST+AGIPDFRS TG Y NLQKY LP+P +F I +F+
Sbjct: 14 GVVDYIKSGKAKKIIFLTGAGISTAAGIPDFRSIGTGFYSNLQKYNLPEPSDVFNIKYFK 73
Query: 437 QNPKPFFTLAKELFPGSFKPTISHIS*DFYMRKGSYYVIIHKTLTH*SEEPAFPK-KN*S 613
+N +PF+ L L PG +KPT H + +KG + + P+ K
Sbjct: 74 ENQEPFYDLCPSLLPGKYKPTFIHYFGAYMAKKGILLKQYTQNIDGLERIAGVPEDKLVE 133
Query: 614 KHTEFYTSHC 643
H F T+HC
Sbjct: 134 SHGTFSTAHC 143
>UniRef50_A1DG07 Cluster: SIR2 family histone deacetylase, putative;
n=3; Trichocomaceae|Rep: SIR2 family histone
deacetylase, putative - Neosartorya fischeri (strain
ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus
fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181))
Length = 425
Score = 116 bits (279), Expect = 6e-25
Identities = 55/137 (40%), Positives = 82/137 (59%), Gaps = 1/137 (0%)
Frame = +2
Query: 260 IVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQ 439
+ ++IK ++I+ + GAGISTSAGIPDFRSP+TGLY NL +LP+P+ +F+I++FR+
Sbjct: 26 VAKYIKEKDVRRIVVMVGAGISTSAGIPDFRSPDTGLYSNLAFLDLPEPEDVFDISYFRE 85
Query: 440 NPKPFFTLAKELFPGSFKPTISHIS*DFYMRKGSYYVIIHKTLTH*SEEPAFP-KKN*SK 616
NP+PF+ LA+EL PG ++PTI+H KG + + P +K
Sbjct: 86 NPRPFYALARELAPGRYRPTIAHSFVKLLHDKGLLLKHFTQNIDCLERLAGVPGEKIVEA 145
Query: 617 HTEFYTSHCLGLPQGIP 667
H F + HC+ P
Sbjct: 146 HGSFASQHCIDCKAAYP 162
>UniRef50_Q07FY7 Cluster: Sirtuin (Silent mating type information
regulation 2 homolog) 3; n=3; Xenopus|Rep: Sirtuin
(Silent mating type information regulation 2 homolog) 3
- Xenopus tropicalis (Western clawed frog) (Silurana
tropicalis)
Length = 401
Score = 116 bits (278), Expect = 7e-25
Identities = 50/83 (60%), Positives = 65/83 (78%)
Frame = +2
Query: 260 IVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQ 439
I+ I + C II ++GAGIST++GIPDFR+P +GLY NLQKY++P P+AIF+IN+F
Sbjct: 117 ILDLITKNCCTNIIVMAGAGISTASGIPDFRTPGSGLYDNLQKYDIPYPEAIFDINYFVC 176
Query: 440 NPKPFFTLAKELFPGSFKPTISH 508
NP PFF LAKELFPG +KP + H
Sbjct: 177 NPNPFFHLAKELFPGKYKPNLVH 199
Score = 71.3 bits (167), Expect = 2e-11
Identities = 35/58 (60%), Positives = 41/58 (70%)
Frame = +1
Query: 451 FLHISKGIISRKL*AYNFTYFIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
F H++K + K YFI+LLH+KGLLLR YTQNID LER AGIP EK+VE HG
Sbjct: 181 FFHLAKELFPGKYKPNLVHYFIKLLHDKGLLLRCYTQNIDGLERLAGIPVEKIVEVHG 238
>UniRef50_Q6FKU1 Cluster: Similar to sp|P53686 Saccharomyces
cerevisiae YPL015c; n=3; Saccharomycetales|Rep: Similar
to sp|P53686 Saccharomyces cerevisiae YPL015c - Candida
glabrata (Yeast) (Torulopsis glabrata)
Length = 364
Score = 115 bits (277), Expect = 1e-24
Identities = 55/137 (40%), Positives = 80/137 (58%), Gaps = 1/137 (0%)
Frame = +2
Query: 260 IVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQ 439
+ +K K+I L GAGISTS+GIPDFRSP+TGLYHNL K +LP +A+F+I ++++
Sbjct: 7 VAEHLKKYPSSKVIFLVGAGISTSSGIPDFRSPKTGLYHNLSKLKLPYAEAVFDIEYYQE 66
Query: 440 NPKPFFTLAKELFPGSFKPTISHIS*DFYMRKGSYYVIIHKTLTH*SEEPAFPKKN-*SK 616
NP+PF+ LA EL+PG+FKP+ H + G + + + E P
Sbjct: 67 NPQPFYLLADELYPGNFKPSKFHYLMKVLEKNGRLRRVYTQNIDTLEREAGIPDDYLVEA 126
Query: 617 HTEFYTSHCLGLPQGIP 667
H F +HC+G + P
Sbjct: 127 HGSFAKNHCIGCDKEFP 143
>UniRef50_UPI0000499DEA Cluster: Sir2 family transcriptional
regulator; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
Sir2 family transcriptional regulator - Entamoeba
histolytica HM-1:IMSS
Length = 383
Score = 115 bits (276), Expect = 1e-24
Identities = 58/140 (41%), Positives = 81/140 (57%), Gaps = 3/140 (2%)
Frame = +2
Query: 257 GIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFR 436
G+ ++I+ + K II L GAG+ST+AGIPDFRSP TGLY NLQKY LP P+A+F++N+F
Sbjct: 124 GVAKYIRKNHVKNIIALVGAGMSTTAGIPDFRSPRTGLYFNLQKYNLPYPEAVFDMNYFP 183
Query: 437 QNPKPFFTLAKELFP--GSFKPTISHIS*DFYMRKGSYYVIIHKTLTH*SEEPAFPK-KN 607
NP PF+ + K +FP G++ PT H KG ++ + + P K
Sbjct: 184 SNPAPFYEVMKVMFPGQGTYFPTKCHRFLKLLNDKGILKMVYTQNIDGLESVAGIPNDKV 243
Query: 608 *SKHTEFYTSHCLGLPQGIP 667
H F +SHCL + P
Sbjct: 244 ICSHGTFRSSHCLSCHKKYP 263
>UniRef50_UPI00004997CB Cluster: Sir2 family transcriptional
regulator; n=2; Entamoeba histolytica HM-1:IMSS|Rep:
Sir2 family transcriptional regulator - Entamoeba
histolytica HM-1:IMSS
Length = 346
Score = 114 bits (275), Expect = 2e-24
Identities = 55/133 (41%), Positives = 82/133 (61%), Gaps = 3/133 (2%)
Frame = +2
Query: 257 GIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFR 436
G ++K + ++ ++GAGISTSAGIPDFR+P TGLY NL+ Y LP P A+F+IN+F+
Sbjct: 92 GFGLFMKYRKPSNVVVMAGAGISTSAGIPDFRTPGTGLYDNLEAYNLPFPTAVFDINYFK 151
Query: 437 QNPKPFFTLAKELFP--GSFKPTISHIS*DFYMRKGSYYVIIHKTLTH*SEEPAFP-KKN 607
NPKPF+T+A EL P G + PT +H + + G ++ + + + FP +K
Sbjct: 152 SNPKPFYTIASELMPGLGKYFPTPTHYFLTYLNKLGYISMLFTQNIDGLEIQSGFPNEKL 211
Query: 608 *SKHTEFYTSHCL 646
H +Y+ HCL
Sbjct: 212 VMAHGNYYSGHCL 224
>UniRef50_Q011Q8 Cluster: NAD-dependent deacetylase SIRT2; n=2;
Ostreococcus|Rep: NAD-dependent deacetylase SIRT2 -
Ostreococcus tauri
Length = 394
Score = 114 bits (275), Expect = 2e-24
Identities = 57/131 (43%), Positives = 78/131 (59%), Gaps = 1/131 (0%)
Frame = +2
Query: 257 GIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFR 436
G+ ++KS R K ++ ++GAGIS SAGIPDFRS E+GLY L +Y+LP PQA+FE+ +F+
Sbjct: 93 GVASYVKSGRAKNVVVMTGAGISVSAGIPDFRS-ESGLYARLGEYDLPYPQAVFELGYFK 151
Query: 437 QNPKPFFTLAKELFPGSFKPTISHIS*DFYMRKGSYYVIIHKTLTH*SEEPAFPK-KN*S 613
P PF+ LAKEL+PG+F PT +H KG + + PK K
Sbjct: 152 DRPGPFYRLAKELYPGAFAPTPTHYFIKLLHDKGILRRCFTQNIDSLERATGLPKEKVVP 211
Query: 614 KHTEFYTSHCL 646
H F +HCL
Sbjct: 212 AHGNFDGAHCL 222
>UniRef50_A4QX96 Cluster: Putative uncharacterized protein; n=2;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 534
Score = 114 bits (275), Expect = 2e-24
Identities = 57/125 (45%), Positives = 75/125 (60%), Gaps = 1/125 (0%)
Frame = +2
Query: 296 IITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAKEL 475
II L+GAGISTSAGIPDFRSP+TGLY NL ++ L P +F+INFFR NP+PF++LA EL
Sbjct: 38 IIILAGAGISTSAGIPDFRSPKTGLYDNLARFSLDSPTDVFDINFFRTNPQPFYSLAPEL 97
Query: 476 FPGSFKPTISHIS*DFYMRKGSYYVIIHKTLTH*SEEPAFPKK-N*SKHTEFYTSHCLGL 652
+PG + PTISH RKG ++ + + + P H F + C+
Sbjct: 98 YPGRYAPTISHAFVALLARKGLLAMLFTQNIDGLEKAAGVPPDLVVEAHGSFDSQRCIDC 157
Query: 653 PQGIP 667
Q P
Sbjct: 158 AQEFP 162
>UniRef50_P53686 Cluster: NAD-dependent deacetylase HST2; n=4;
Saccharomyces cerevisiae|Rep: NAD-dependent deacetylase
HST2 - Saccharomyces cerevisiae (Baker's yeast)
Length = 357
Score = 113 bits (272), Expect = 4e-24
Identities = 60/145 (41%), Positives = 86/145 (59%), Gaps = 2/145 (1%)
Frame = +2
Query: 260 IVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQ 439
I +KS+ K+I + GAGISTS GIPDFRSP TGLYHNL + +LP P+A+F+++FF+
Sbjct: 15 IAAHMKSNPNAKVIFMVGAGISTSCGIPDFRSPGTGLYHNLARLKLPYPEAVFDVDFFQS 74
Query: 440 NPKPFFTLAKELFPGSFKPTISHIS*DFYMRKGSYYVIIHKTLTH*SEEPAFPKKN--*S 613
+P PF+TLAKEL+PG+F+P+ H + K + + + E A K +
Sbjct: 75 DPLPFYTLAKELYPGNFRPSKFHYLLKLFQDKDVLKRVYTQNIDT-LERQAGVKDDLIIE 133
Query: 614 KHTEFYTSHCLGLPQGIPTGVCQRK 688
H F HC+G + P V + K
Sbjct: 134 AHGSFAHCHCIGCGKVYPPQVFKSK 158
>UniRef50_UPI00005A356B Cluster: PREDICTED: similar to NAD-dependent
deacetylase sirtuin-3, mitochondrial precursor
(SIR2-like protein 3) (hSIRT3) isoform 1; n=2; Canis
lupus familiaris|Rep: PREDICTED: similar to
NAD-dependent deacetylase sirtuin-3, mitochondrial
precursor (SIR2-like protein 3) (hSIRT3) isoform 1 -
Canis familiaris
Length = 248
Score = 112 bits (270), Expect = 7e-24
Identities = 47/83 (56%), Positives = 65/83 (78%)
Frame = +2
Query: 260 IVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQ 439
I I++ C++++ + GAGIST +GIPDFRSP +GLY NLQ+Y+LP P+A+FE+ FF
Sbjct: 101 IAELIRARACQRVLVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAVFELAFFSH 160
Query: 440 NPKPFFTLAKELFPGSFKPTISH 508
NPKPFFTLAKEL+ +++P I H
Sbjct: 161 NPKPFFTLAKELYLKNYRPNIIH 183
Score = 50.4 bits (115), Expect = 4e-05
Identities = 25/53 (47%), Positives = 32/53 (60%)
Frame = +1
Query: 427 FLQAKSQTFLHISKGIISRKL*AYNFTYFIRLLHEKGLLLRHYTQNIDTLERG 585
F + F ++K + + YF+RLLH+KGLLLR YTQNID LERG
Sbjct: 157 FFSHNPKPFFTLAKELYLKNYRPNIIHYFLRLLHDKGLLLRLYTQNIDGLERG 209
>UniRef50_Q9USN7 Cluster: Sir2 family histone deacetylase Hst2; n=1;
Schizosaccharomyces pombe|Rep: Sir2 family histone
deacetylase Hst2 - Schizosaccharomyces pombe (Fission
yeast)
Length = 332
Score = 111 bits (267), Expect = 2e-23
Identities = 45/79 (56%), Positives = 64/79 (81%)
Frame = +2
Query: 272 IKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKP 451
IK + KKI + GAGIST+AGIPDFRSPETG+Y+NLQ++ LP +A+F++++FR+NP+P
Sbjct: 22 IKEGKVKKICVMVGAGISTAAGIPDFRSPETGIYNNLQRFNLPYAEAVFDLSYFRKNPRP 81
Query: 452 FFTLAKELFPGSFKPTISH 508
F+ LA EL P ++PT +H
Sbjct: 82 FYELAHELMPEKYRPTYTH 100
Score = 63.7 bits (148), Expect = 4e-09
Identities = 28/39 (71%), Positives = 34/39 (87%)
Frame = +1
Query: 508 YFIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
YFIRLLH+K LL + YTQNIDTLER AG+P++ L+EAHG
Sbjct: 101 YFIRLLHDKRLLQKCYTQNIDTLERLAGVPDKALIEAHG 139
>UniRef50_Q4WFZ3 Cluster: SIR2 family histone deacetylase, putative;
n=4; Trichocomaceae|Rep: SIR2 family histone
deacetylase, putative - Aspergillus fumigatus (Sartorya
fumigata)
Length = 403
Score = 111 bits (267), Expect = 2e-23
Identities = 55/129 (42%), Positives = 76/129 (58%), Gaps = 1/129 (0%)
Frame = +2
Query: 260 IVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQ 439
I IKS + KI+ L GAGIST+AGIPDFRSPETG+Y L+ LP P+AIF IN+FR
Sbjct: 83 IANLIKSGQVHKIVVLVGAGISTAAGIPDFRSPETGIYDRLKPLHLPYPEAIFHINYFRH 142
Query: 440 NPKPFFTLAKELFPGSFKPTISHIS*DFYMRKGSYYVIIHKTLTH*SEEPAFPK-KN*SK 616
P+PF+ +A+ P S KPTI+H +KG + + + + + P+ K +
Sbjct: 143 TPEPFYAIARARHPRSLKPTITHAFLALLEKKGLLHFVFTQNIDGLERDVGIPEDKILNA 202
Query: 617 HTEFYTSHC 643
H + T C
Sbjct: 203 HGSWRTQRC 211
>UniRef50_A1CD03 Cluster: SIR2 family histone deacetylase, putative;
n=2; Trichocomaceae|Rep: SIR2 family histone
deacetylase, putative - Aspergillus clavatus
Length = 329
Score = 109 bits (263), Expect = 5e-23
Identities = 53/129 (41%), Positives = 77/129 (59%), Gaps = 1/129 (0%)
Frame = +2
Query: 260 IVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQ 439
I IKS + ++I+ L GAGIST+AGIPDFRSPETG+Y L+ LP P+AIF IN+FR
Sbjct: 7 IATLIKSGQIRRIVVLVGAGISTAAGIPDFRSPETGIYDRLKPLGLPYPEAIFHINYFRH 66
Query: 440 NPKPFFTLAKELFPGSFKPTISHIS*DFYMRKGSYYVIIHKTLTH*SEEPAFPK-KN*SK 616
P+PF+ +A+ P + KPTI+H +K + + + + + P+ K +
Sbjct: 67 TPEPFYAIARARHPRTLKPTITHAFLALLAKKNLLHFLFTQNIDGLERDTGVPENKILNA 126
Query: 617 HTEFYTSHC 643
H + T HC
Sbjct: 127 HGSWRTQHC 135
>UniRef50_Q4S7H2 Cluster: Chromosome 13 SCAF14715, whole genome
shotgun sequence; n=6; Clupeocephala|Rep: Chromosome 13
SCAF14715, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 327
Score = 109 bits (262), Expect = 6e-23
Identities = 43/83 (51%), Positives = 64/83 (77%)
Frame = +2
Query: 260 IVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQ 439
+ R +K RC+ ++ ++GAGIST++GIPDFR+P TGLY NL++Y+LP P+A+F I++F
Sbjct: 39 VARLVKLGRCRNVVVVAGAGISTASGIPDFRTPGTGLYANLEQYKLPYPEAVFSIDYFSD 98
Query: 440 NPKPFFTLAKELFPGSFKPTISH 508
+P PFF+LAK L+PG +P H
Sbjct: 99 DPLPFFSLAKALYPGHHRPNYIH 121
Score = 68.9 bits (161), Expect = 1e-10
Identities = 31/39 (79%), Positives = 34/39 (87%)
Frame = +1
Query: 508 YFIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
YF+R+LH KGLLLR YTQNID LER GIPE+KLVEAHG
Sbjct: 122 YFVRMLHHKGLLLRVYTQNIDGLERLCGIPEDKLVEAHG 160
>UniRef50_O94066 Cluster: Transcription regulatory protein; n=6;
Saccharomycetales|Rep: Transcription regulatory protein
- Candida albicans (Yeast)
Length = 331
Score = 107 bits (258), Expect = 2e-22
Identities = 46/73 (63%), Positives = 60/73 (82%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAK 469
KK+ +GAGIST AGIPDFRSP+TGLY NL K LP +A+F+I+FF+++PKPF+TLA+
Sbjct: 19 KKVTFFNGAGISTGAGIPDFRSPDTGLYANLAKLNLPFAEAVFDIDFFKEDPKPFYTLAE 78
Query: 470 ELFPGSFKPTISH 508
EL+PG+F PT H
Sbjct: 79 ELYPGNFAPTKFH 91
Score = 55.2 bits (127), Expect = 1e-06
Identities = 25/41 (60%), Positives = 33/41 (80%)
Frame = +1
Query: 502 FTYFIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
F +FI+LL ++G L R YTQNIDTLER AG+ ++ +VEAHG
Sbjct: 90 FHHFIKLLQDQGSLKRVYTQNIDTLERLAGVEDKYIVEAHG 130
>UniRef50_Q8R104 Cluster: NAD-dependent deacetylase sirtuin-3; n=8;
Deuterostomia|Rep: NAD-dependent deacetylase sirtuin-3 -
Mus musculus (Mouse)
Length = 257
Score = 107 bits (258), Expect = 2e-22
Identities = 44/66 (66%), Positives = 56/66 (84%)
Frame = +2
Query: 311 GAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAKELFPGSF 490
GAGIST +GIPDFRSP +GLY NLQ+Y++P P+AIFE+ FF NPKPFF LAKEL+PG +
Sbjct: 3 GAGISTPSGIPDFRSPGSGLYSNLQQYDIPYPEAIFELGFFFHNPKPFFMLAKELYPGHY 62
Query: 491 KPTISH 508
+P ++H
Sbjct: 63 RPNVTH 68
Score = 65.7 bits (153), Expect = 1e-09
Identities = 30/39 (76%), Positives = 33/39 (84%)
Frame = +1
Query: 508 YFIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
YF+RLLH+K LLLR YTQNID LER +GIP KLVEAHG
Sbjct: 69 YFLRLLHDKELLLRLYTQNIDGLERASGIPASKLVEAHG 107
>UniRef50_Q4P1X1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 434
Score = 107 bits (257), Expect = 3e-22
Identities = 50/95 (52%), Positives = 66/95 (69%), Gaps = 2/95 (2%)
Frame = +2
Query: 257 GIVRWIKSDRCKKIITLSGAGISTSAG--IPDFRSPETGLYHNLQKYELPQPQAIFEINF 430
G+ + S + +I L+GAGISTSA IPDFRSP TGLY NL Y LP +AIF+I +
Sbjct: 38 GVASLLASPTTRNVIVLAGAGISTSASPPIPDFRSPGTGLYANLAAYNLPYAEAIFDIGY 97
Query: 431 FRQNPKPFFTLAKELFPGSFKPTISHIS*DFYMRK 535
F+++P+PFFTLAK L+PG+FKP ++H RK
Sbjct: 98 FQRHPQPFFTLAKHLYPGNFKPALAHYFLTLLQRK 132
Score = 52.0 bits (119), Expect = 1e-05
Identities = 27/66 (40%), Positives = 37/66 (56%)
Frame = +1
Query: 427 FLQAKSQTFLHISKGIISRKL*AYNFTYFIRLLHEKGLLLRHYTQNIDTLERGAGIPEEK 606
+ Q Q F ++K + YF+ LL K L R +TQN+DTLER AG+ +K
Sbjct: 97 YFQRHPQPFFTLAKHLYPGNFKPALAHYFLTLLQRKQKLKRVFTQNVDTLERIAGVEADK 156
Query: 607 LVEAHG 624
+VEAHG
Sbjct: 157 VVEAHG 162
>UniRef50_A2GAR7 Cluster: Transcriptional regulator, Sir2 family
protein; n=1; Trichomonas vaginalis G3|Rep:
Transcriptional regulator, Sir2 family protein -
Trichomonas vaginalis G3
Length = 312
Score = 105 bits (253), Expect = 8e-22
Identities = 43/84 (51%), Positives = 62/84 (73%)
Frame = +2
Query: 257 GIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFR 436
G+V++IKS + L+GAG S ++GIPDFR+P+ GLY NL KY+LP P+A+F+I FF
Sbjct: 23 GLVKYIKSGHATNTVFLTGAGTSVASGIPDFRTPKIGLYANLDKYKLPYPEAVFDIEFFD 82
Query: 437 QNPKPFFTLAKELFPGSFKPTISH 508
NP PFF + + + PG+FKP+ +H
Sbjct: 83 TNPGPFFDVCRNILPGTFKPSPAH 106
Score = 44.8 bits (101), Expect = 0.002
Identities = 21/40 (52%), Positives = 31/40 (77%), Gaps = 1/40 (2%)
Frame = +1
Query: 508 YFIRLLHEKG-LLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
+++ +L +K LL R YTQNID+L+ AG+P +K+VEAHG
Sbjct: 106 HYLPVLFDKHKLLTRLYTQNIDSLDISAGLPLDKIVEAHG 145
>UniRef50_Q1RL71 Cluster: Zinc finger protein; n=2; Ciona
intestinalis|Rep: Zinc finger protein - Ciona
intestinalis (Transparent sea squirt)
Length = 523
Score = 105 bits (251), Expect = 1e-21
Identities = 46/84 (54%), Positives = 61/84 (72%), Gaps = 1/84 (1%)
Frame = +2
Query: 260 IVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQ 439
+ I S + II ++GAGIST +GIPDFR+P TGLY NL KY++P P A+F+ ++F
Sbjct: 110 VAELISSGGVRNIIVMAGAGISTGSGIPDFRTPGTGLYDNLHKYKIPAPTAVFDRDYFNV 169
Query: 440 NPKPFFTLAKELFP-GSFKPTISH 508
NPKPFF LAKEL+P G ++P I H
Sbjct: 170 NPKPFFELAKELYPSGKYRPNIVH 193
Score = 68.5 bits (160), Expect = 1e-10
Identities = 32/39 (82%), Positives = 33/39 (84%)
Frame = +1
Query: 508 YFIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
YF+R LHEKGLLLR YTQNID LER AGIP KLVEAHG
Sbjct: 194 YFVRCLHEKGLLLRMYTQNIDGLERLAGIPPSKLVEAHG 232
>UniRef50_Q54P49 Cluster: Zn finger-containing protein; n=1;
Dictyostelium discoideum AX4|Rep: Zn finger-containing
protein - Dictyostelium discoideum AX4
Length = 456
Score = 102 bits (244), Expect = 1e-20
Identities = 46/85 (54%), Positives = 68/85 (80%), Gaps = 3/85 (3%)
Frame = +2
Query: 263 VRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYH--NLQKYELPQPQAIFEINFFR 436
++ IK+D+CK II L+GAGIS ++GIPDFRS ETGLY+ N+ K++LP +A+F+I++F+
Sbjct: 172 IKLIKNDKCKNIIVLTGAGISVASGIPDFRSVETGLYNNENVSKFKLPFKEAVFDIDYFK 231
Query: 437 QNPKPFFTLAKELFP-GSFKPTISH 508
NP+PF+ L+K+L+P G FK T H
Sbjct: 232 FNPEPFYQLSKDLYPSGKFKCTPVH 256
Score = 65.7 bits (153), Expect = 1e-09
Identities = 34/67 (50%), Positives = 44/67 (65%), Gaps = 1/67 (1%)
Frame = +1
Query: 427 FLQAKSQTFLHISKGII-SRKL*AYNFTYFIRLLHEKGLLLRHYTQNIDTLERGAGIPEE 603
+ + + F +SK + S K YFI+LL +KGLLLR+Y QN DTLER AGIP +
Sbjct: 229 YFKFNPEPFYQLSKDLYPSGKFKCTPVHYFIKLLSDKGLLLRNYAQNADTLERIAGIPLD 288
Query: 604 KLVEAHG 624
KL+EAHG
Sbjct: 289 KLIEAHG 295
>UniRef50_A7SX90 Cluster: Predicted protein; n=3; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 306
Score = 102 bits (244), Expect = 1e-20
Identities = 49/85 (57%), Positives = 64/85 (75%), Gaps = 2/85 (2%)
Frame = +2
Query: 260 IVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQ-KY-ELPQPQAIFEINFF 433
+VR IK +CK II L+GAG+S S GIPDFRS + G+Y L +Y +LP PQA+F+I +F
Sbjct: 62 VVRLIK--KCKNIIVLTGAGVSVSCGIPDFRSRD-GIYAKLSVEYPDLPDPQAMFDITYF 118
Query: 434 RQNPKPFFTLAKELFPGSFKPTISH 508
QNPKPFF AKE++PG FKP++ H
Sbjct: 119 NQNPKPFFKFAKEIYPGQFKPSLCH 143
Score = 42.7 bits (96), Expect = 0.008
Identities = 21/38 (55%), Positives = 28/38 (73%)
Frame = +1
Query: 511 FIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
FI L E G LLR+Y+QNIDTLE+ AGI ++++ HG
Sbjct: 145 FIHQLEEHGHLLRNYSQNIDTLEQVAGI--TRVIQCHG 180
>UniRef50_A2F8N6 Cluster: Transcriptional regulator, Sir2 family
protein; n=1; Trichomonas vaginalis G3|Rep:
Transcriptional regulator, Sir2 family protein -
Trichomonas vaginalis G3
Length = 320
Score = 101 bits (243), Expect = 1e-20
Identities = 43/84 (51%), Positives = 61/84 (72%)
Frame = +2
Query: 257 GIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFR 436
GIV +I KKI+ SGAG S ++GIPDFRSP+ GLY L+KY LP+P++IF ++F+
Sbjct: 26 GIVSFINEGNAKKILIFSGAGTSVASGIPDFRSPKIGLYSQLKKYNLPRPESIFTRDYFK 85
Query: 437 QNPKPFFTLAKELFPGSFKPTISH 508
+P+PFF+L K PG +KP+ +H
Sbjct: 86 YHPEPFFSLIKFFLPGKYKPSPAH 109
Score = 51.6 bits (118), Expect = 2e-05
Identities = 22/41 (53%), Positives = 29/41 (70%)
Frame = +1
Query: 508 YFIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHGIL 630
+ +L G+LLRHY+QNID L++ AG+ EE LVE HG L
Sbjct: 110 FLAKLFENHGILLRHYSQNIDGLDKAAGLSEEHLVEWHGTL 150
>UniRef50_Q5BVF7 Cluster: SJCHGC03105 protein; n=2; Schistosoma
japonicum|Rep: SJCHGC03105 protein - Schistosoma
japonicum (Blood fluke)
Length = 181
Score = 101 bits (242), Expect = 2e-20
Identities = 41/84 (48%), Positives = 62/84 (73%)
Frame = +2
Query: 257 GIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFR 436
G+ + I+ + KI+T+ GAGIST+AGIPDFRSP +G+Y NL+++ LP P IF I +F+
Sbjct: 51 GVSQLIQDGKINKIVTMVGAGISTAAGIPDFRSPSSGVYDNLEEFNLPTPTTIFSIEYFQ 110
Query: 437 QNPKPFFTLAKELFPGSFKPTISH 508
+P+PFF +A+ L+ KPT++H
Sbjct: 111 HDPRPFFEIARRLYRPEAKPTLAH 134
Score = 40.7 bits (91), Expect = 0.034
Identities = 22/61 (36%), Positives = 32/61 (52%)
Frame = +1
Query: 379 LTEVRTTSTTGDIRNKFLQAKSQTFLHISKGIISRKL*AYNFTYFIRLLHEKGLLLRHYT 558
L E + T ++ Q + F I++ + + YFI+LLH+KGLLLRHYT
Sbjct: 92 LEEFNLPTPTTIFSIEYFQHDPRPFFEIARRLYRPEAKPTLAHYFIKLLHDKGLLLRHYT 151
Query: 559 Q 561
Q
Sbjct: 152 Q 152
>UniRef50_A7RLD5 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 335
Score = 98.7 bits (235), Expect = 1e-19
Identities = 40/68 (58%), Positives = 55/68 (80%)
Frame = +2
Query: 305 LSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAKELFPG 484
++GAGIST +GIPDFR+P TGLY NLQ+Y +P+P AIF+I +F +P+PFF LAK L+PG
Sbjct: 1 MAGAGISTPSGIPDFRTPGTGLYDNLQEYNIPEPTAIFDIEYFWYDPRPFFCLAKTLYPG 60
Query: 485 SFKPTISH 508
+++P H
Sbjct: 61 NYQPNYVH 68
Score = 68.1 bits (159), Expect = 2e-10
Identities = 33/54 (61%), Positives = 41/54 (75%)
Frame = +1
Query: 508 YFIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHGILHITLSGIAARNTH 669
YF++LLH+KG LLR YTQNID LER AG+P EKLVEAHG T S I+ +++
Sbjct: 69 YFVKLLHDKGFLLRMYTQNIDGLERLAGLPAEKLVEAHGTFS-TASCISCHHSY 121
>UniRef50_UPI00006CA40C Cluster: transcriptional regulator, Sir2
family protein; n=1; Tetrahymena thermophila SB210|Rep:
transcriptional regulator, Sir2 family protein -
Tetrahymena thermophila SB210
Length = 471
Score = 97.5 bits (232), Expect = 3e-19
Identities = 51/119 (42%), Positives = 70/119 (58%), Gaps = 1/119 (0%)
Frame = +2
Query: 293 KIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAKE 472
+I+ L+GAGIS SAGIPDFR+P +GLY LQKY+LP P+AIFEIN+F+ +P+PF+TL KE
Sbjct: 213 RIVFLTGAGISVSAGIPDFRTPGSGLYSQLQKYKLPYPEAIFEINYFKHHPQPFYTLCKE 272
Query: 473 LFPGSFKPTISHIS*DFYMRKGSYYVIIHKTLTH*SEEPAFPK-KN*SKHTEFYTSHCL 646
T SH R+ + + + E P+ K H F T+ C+
Sbjct: 273 FSSCGSHFTSSHFFIAETNRRNRLLINFSQNIDGLELEAGLPESKLVQAHGHFRTAKCV 331
>UniRef50_A0C6J0 Cluster: Chromosome undetermined scaffold_152,
whole genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_152,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 449
Score = 95.5 bits (227), Expect = 1e-18
Identities = 40/84 (47%), Positives = 63/84 (75%), Gaps = 1/84 (1%)
Frame = +2
Query: 260 IVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQ 439
+V +K+ + +++ L+GAG+S +AGIPDFR+P TGLY +QKY LP P+++FEI +F++
Sbjct: 200 LVDGLKNKKFQRVCVLAGAGMSVAAGIPDFRTPGTGLYSQIQKYNLPSPESVFEIEYFKK 259
Query: 440 NPKPFFTLAKE-LFPGSFKPTISH 508
NP+ F+ +AKE L KPT++H
Sbjct: 260 NPEAFYCVAKEFLLSFDAKPTLAH 283
Score = 46.0 bits (104), Expect = 9e-04
Identities = 18/38 (47%), Positives = 29/38 (76%)
Frame = +1
Query: 511 FIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
F++ L +G LL+ +TQNID LE AG+ ++K+++AHG
Sbjct: 285 FLKFLDSRGQLLKCFTQNIDGLELDAGVSQDKVIQAHG 322
>UniRef50_Q96EB6 Cluster: NAD-dependent deacetylase sirtuin-1; n=29;
Euteleostomi|Rep: NAD-dependent deacetylase sirtuin-1 -
Homo sapiens (Human)
Length = 747
Score = 94.7 bits (225), Expect = 2e-18
Identities = 42/76 (55%), Positives = 58/76 (76%), Gaps = 2/76 (2%)
Frame = +2
Query: 287 CKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKY--ELPQPQAIFEINFFRQNPKPFFT 460
CKKII L+GAG+S S GIPDFRS + G+Y L +LP PQA+F+I +FR++P+PFF
Sbjct: 253 CKKIIVLTGAGVSVSCGIPDFRSRD-GIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFK 311
Query: 461 LAKELFPGSFKPTISH 508
AKE++PG F+P++ H
Sbjct: 312 FAKEIYPGQFQPSLCH 327
Score = 44.8 bits (101), Expect = 0.002
Identities = 21/38 (55%), Positives = 30/38 (78%)
Frame = +1
Query: 511 FIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
FI L ++G LLR+YTQNIDTLE+ AGI +++++ HG
Sbjct: 329 FIALSDKEGKLLRNYTQNIDTLEQVAGI--QRIIQCHG 364
>UniRef50_Q7QZ36 Cluster: GLP_464_21655_23334; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_464_21655_23334 - Giardia lamblia
ATCC 50803
Length = 559
Score = 93.1 bits (221), Expect = 6e-18
Identities = 51/136 (37%), Positives = 76/136 (55%), Gaps = 2/136 (1%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTL 463
R +K+I L GAGIS SAGIPDFRS + G+Y+ LQ+Y L +P +F ++FFR NP PF+
Sbjct: 162 RARKVIFLVGAGISVSAGIPDFRS-KNGIYNRLQQYNLQKPTDMFNLDFFRGNPIPFYRF 220
Query: 464 AKELFPG-SFKPTISHIS*DFYMRKGSYYVIIHKTLTH*SEEPAFPKKN-*SKHTEFYTS 637
E+FPG FKPT+ H+ ++G I + + + +K + H F+T
Sbjct: 221 CPEIFPGPQFKPTVVHLFMRLLEKRGQLQRIYTQNIDCLEVQAQITQKYIINCHGSFHTF 280
Query: 638 HCLGLPQGIPTGVCQR 685
C+ P + +R
Sbjct: 281 TCIDCGAKFPMELLRR 296
>UniRef50_UPI00015B57C0 Cluster: PREDICTED: similar to GA18743-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA18743-PA - Nasonia vitripennis
Length = 871
Score = 91.9 bits (218), Expect = 1e-17
Identities = 45/85 (52%), Positives = 62/85 (72%), Gaps = 2/85 (2%)
Frame = +2
Query: 260 IVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNL-QKY-ELPQPQAIFEINFF 433
+V IK+ K II L+GAG+S S GIPDFRS + G+Y L Q + +LP PQA+F+IN+F
Sbjct: 197 VVELIKNS--KNIIVLTGAGVSVSCGIPDFRSRD-GIYSRLAQDFPDLPDPQAMFDINYF 253
Query: 434 RQNPKPFFTLAKELFPGSFKPTISH 508
Q+P+PFF A+E++PG FKP+ H
Sbjct: 254 SQDPRPFFKFAREIYPGQFKPSPCH 278
Score = 45.2 bits (102), Expect = 0.002
Identities = 22/38 (57%), Positives = 29/38 (76%)
Frame = +1
Query: 511 FIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
FI++L ++ LLR+Y+QNIDTLER AGI L+E HG
Sbjct: 280 FIKMLEKQKKLLRNYSQNIDTLERVAGI--NNLIECHG 315
>UniRef50_Q1RPU3 Cluster: Zinc finger protein; n=1; Ciona
intestinalis|Rep: Zinc finger protein - Ciona
intestinalis (Transparent sea squirt)
Length = 737
Score = 91.5 bits (217), Expect = 2e-17
Identities = 43/84 (51%), Positives = 62/84 (73%), Gaps = 2/84 (2%)
Frame = +2
Query: 263 VRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKY--ELPQPQAIFEINFFR 436
+R IK+ KKI+ L+GAG+S S GIPDFRS + G+Y L +LP PQA+F+I++F+
Sbjct: 182 IRLIKTS--KKILVLTGAGVSVSCGIPDFRSRD-GIYSRLSVDFPDLPNPQAMFDIHYFK 238
Query: 437 QNPKPFFTLAKELFPGSFKPTISH 508
+P+PFF AKE++PG FKP+ +H
Sbjct: 239 HDPRPFFKFAKEIYPGQFKPSRAH 262
Score = 47.2 bits (107), Expect = 4e-04
Identities = 24/38 (63%), Positives = 29/38 (76%)
Frame = +1
Query: 511 FIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
FI LL + G LLR+YTQNIDTLE+ AGI K+V+ HG
Sbjct: 264 FISLLEKTGRLLRNYTQNIDTLEQVAGI--SKVVQCHG 299
>UniRef50_Q5KA61 Cluster: Histone deacetylase, putative; n=1;
Filobasidiella neoformans|Rep: Histone deacetylase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 596
Score = 91.5 bits (217), Expect = 2e-17
Identities = 44/78 (56%), Positives = 57/78 (73%), Gaps = 3/78 (3%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQ---KYELPQPQAIFEINFFRQNPKPF 454
+ KKII LSGAGISTS GIPDFRS TGLY LQ KYEL PQ +F+I +FR+ P+ F
Sbjct: 155 KSKKIIVLSGAGISTSCGIPDFRS-STGLYAQLQEEGKYELDDPQQMFDIRYFREKPEVF 213
Query: 455 FTLAKELFPGSFKPTISH 508
++ AK+++P +F P+ H
Sbjct: 214 YSFAKQIYPSNFVPSPCH 231
Score = 48.4 bits (110), Expect = 2e-04
Identities = 24/67 (35%), Positives = 41/67 (61%)
Frame = +1
Query: 424 KFLQAKSQTFLHISKGIISRKL*AYNFTYFIRLLHEKGLLLRHYTQNIDTLERGAGIPEE 603
++ + K + F +K I +I++L ++G+LLR+YTQNIDTLE AG+ E
Sbjct: 204 RYFREKPEVFYSFAKQIYPSNFVPSPCHRWIKMLEDRGVLLRNYTQNIDTLESLAGV--E 261
Query: 604 KLVEAHG 624
++++ HG
Sbjct: 262 RVLQCHG 268
>UniRef50_UPI000051AA14 Cluster: PREDICTED: similar to NAD-dependent
deacetylase sirtuin-1 (hSIRT1) (hSIR2) (SIR2-like
protein 1); n=1; Apis mellifera|Rep: PREDICTED: similar
to NAD-dependent deacetylase sirtuin-1 (hSIRT1) (hSIR2)
(SIR2-like protein 1) - Apis mellifera
Length = 868
Score = 90.2 bits (214), Expect = 4e-17
Identities = 43/85 (50%), Positives = 63/85 (74%), Gaps = 2/85 (2%)
Frame = +2
Query: 260 IVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNL-QKY-ELPQPQAIFEINFF 433
+VR I++ +II L+GAG+S S GIPDFRS + G+Y L Q + +LP PQA+F+IN+F
Sbjct: 196 VVRLIRNSN--RIIVLTGAGVSVSCGIPDFRSRD-GIYSRLAQDFPDLPDPQAMFDINYF 252
Query: 434 RQNPKPFFTLAKELFPGSFKPTISH 508
Q+P+PF+ A+E++PG FKP+ H
Sbjct: 253 SQDPRPFYKFAREIYPGQFKPSPCH 277
Score = 44.0 bits (99), Expect = 0.004
Identities = 21/38 (55%), Positives = 30/38 (78%)
Frame = +1
Query: 511 FIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
FI++L ++ LLR+Y+QNIDTLE+ AGI E ++E HG
Sbjct: 279 FIKMLDKQKKLLRNYSQNIDTLEQVAGI--ENVIECHG 314
>UniRef50_Q54GV7 Cluster: NAD(+)-dependent deacetylase, silent
information regulator protein (Sir2) family protein;
n=1; Dictyostelium discoideum AX4|Rep: NAD(+)-dependent
deacetylase, silent information regulator protein (Sir2)
family protein - Dictyostelium discoideum AX4
Length = 542
Score = 89.8 bits (213), Expect = 6e-17
Identities = 38/74 (51%), Positives = 57/74 (77%), Gaps = 1/74 (1%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQK-YELPQPQAIFEINFFRQNPKPFFTLA 466
K I+ ++GAG+S S GIPDFRS + G+Y ++K Y LP+P+++F+I++ R NP PFF A
Sbjct: 301 KNIVIITGAGVSVSCGIPDFRS-KGGVYETIEKKYNLPRPESLFDIHYLRANPLPFFEFA 359
Query: 467 KELFPGSFKPTISH 508
KE+FPG+ KP+ +H
Sbjct: 360 KEIFPGNHKPSPTH 373
Score = 59.3 bits (137), Expect = 9e-08
Identities = 33/66 (50%), Positives = 38/66 (57%)
Frame = +1
Query: 427 FLQAKSQTFLHISKGIISRKL*AYNFTYFIRLLHEKGLLLRHYTQNIDTLERGAGIPEEK 606
+L+A F +K I FI+LL EKG LLR+YTQNIDTLE AGI EK
Sbjct: 347 YLRANPLPFFEFAKEIFPGNHKPSPTHSFIKLLDEKGKLLRNYTQNIDTLEHVAGIDREK 406
Query: 607 LVEAHG 624
LV HG
Sbjct: 407 LVNCHG 412
>UniRef50_A6XDL2 Cluster: Sirtuin 1; n=2; Schistosoma|Rep: Sirtuin 1
- Schistosoma mansoni (Blood fluke)
Length = 568
Score = 89.4 bits (212), Expect = 7e-17
Identities = 41/76 (53%), Positives = 57/76 (75%), Gaps = 2/76 (2%)
Frame = +2
Query: 287 CKKIITLSGAGISTSAGIPDFRSPETGLYHNLQK-Y-ELPQPQAIFEINFFRQNPKPFFT 460
C I+ ++GAGIS S GIPDFRS + G+Y L + Y +L PQA+F++++F++NP PFF
Sbjct: 154 CTSILVITGAGISVSCGIPDFRSRD-GIYARLSRDYPDLSSPQAMFDMSYFKRNPIPFFK 212
Query: 461 LAKELFPGSFKPTISH 508
AKELFPG F P+I+H
Sbjct: 213 FAKELFPGQFSPSITH 228
Score = 44.4 bits (100), Expect = 0.003
Identities = 22/37 (59%), Positives = 27/37 (72%)
Frame = +1
Query: 514 IRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
I LL K LLR+YTQNIDTLE+ AGI +L++ HG
Sbjct: 231 IALLESKDKLLRNYTQNIDTLEQAAGI--TRLIQCHG 265
>UniRef50_Q21921 Cluster: NAD-dependent deacetylase SIR2 homolog;
n=2; Caenorhabditis|Rep: NAD-dependent deacetylase SIR2
homolog - Caenorhabditis elegans
Length = 607
Score = 89.4 bits (212), Expect = 7e-17
Identities = 39/75 (52%), Positives = 55/75 (73%), Gaps = 2/75 (2%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQKY--ELPQPQAIFEINFFRQNPKPFFTL 463
K I+ L+GAG+S S GIPDFRS + G+Y L+ +LP P A+F+I +FR+NP PF+
Sbjct: 146 KHILVLTGAGVSVSCGIPDFRSKD-GIYARLRSEFPDLPDPTAMFDIRYFRENPAPFYNF 204
Query: 464 AKELFPGSFKPTISH 508
A+E+FPG F P++SH
Sbjct: 205 AREIFPGQFVPSVSH 219
Score = 44.0 bits (99), Expect = 0.004
Identities = 22/38 (57%), Positives = 27/38 (71%)
Frame = +1
Query: 511 FIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
FI+ L G LLR+YTQNIDTLE GI +++VE HG
Sbjct: 221 FIKELETSGRLLRNYTQNIDTLEHQTGI--KRVVECHG 256
>UniRef50_UPI0001555321 Cluster: PREDICTED: similar to sirtuin
(silent mating type information regulation 2 homolog) 3
(S. cerevisiae), partial; n=1; Ornithorhynchus
anatinus|Rep: PREDICTED: similar to sirtuin (silent
mating type information regulation 2 homolog) 3 (S.
cerevisiae), partial - Ornithorhynchus anatinus
Length = 148
Score = 88.6 bits (210), Expect = 1e-16
Identities = 36/64 (56%), Positives = 49/64 (76%)
Frame = +2
Query: 317 GISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAKELFPGSFKP 496
G +AG RSP +GLY NLQ+Y +P P+AIFE+ FF ++PKPFFTLAKEL+PG+++P
Sbjct: 60 GTEQAAGTRGLRSPGSGLYSNLQQYAIPYPEAIFELAFFHRDPKPFFTLAKELYPGNYRP 119
Query: 497 TISH 508
+H
Sbjct: 120 NFAH 123
Score = 48.0 bits (109), Expect = 2e-04
Identities = 23/29 (79%), Positives = 25/29 (86%), Gaps = 1/29 (3%)
Frame = +1
Query: 499 NFT-YFIRLLHEKGLLLRHYTQNIDTLER 582
NF YF+RLLH+KGLLLR YTQNID LER
Sbjct: 120 NFAHYFLRLLHDKGLLLRLYTQNIDGLER 148
>UniRef50_A4VDQ9 Cluster: Chromatin regulatory protein sir2; n=1;
Tetrahymena thermophila SB210|Rep: Chromatin regulatory
protein sir2 - Tetrahymena thermophila SB210
Length = 279
Score = 88.6 bits (210), Expect = 1e-16
Identities = 49/130 (37%), Positives = 73/130 (56%), Gaps = 2/130 (1%)
Frame = +2
Query: 263 VRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKY-ELPQPQAIFEINFFRQ 439
V ++K R KKII L+GAGIST+AGIPDFRS +TGLY L+K + P+ IF I++++Q
Sbjct: 22 VNFLKERRFKKIIVLTGAGISTNAGIPDFRSKDTGLYARLKKSGQFSYPEQIFTIDYYQQ 81
Query: 440 NPKPFFTLAKELFPGSFKPTISHIS*DFYMRKGSYYVIIHKTLTH*SEEPAFPKKN-*SK 616
N KPF+ + +E ++P SH ++ Y+ I + + + KK
Sbjct: 82 NHKPFYEICREFVQKEYEPQQSHKFITELAKQNLLYLNITQNIDGLELKAGLDKKYLIQA 141
Query: 617 HTEFYTSHCL 646
H SHC+
Sbjct: 142 HGNLEKSHCI 151
>UniRef50_Q7S6G9 Cluster: Putative uncharacterized protein
NCU04737.1; n=3; Sordariomycetes|Rep: Putative
uncharacterized protein NCU04737.1 - Neurospora crassa
Length = 670
Score = 88.2 bits (209), Expect = 2e-16
Identities = 50/131 (38%), Positives = 72/131 (54%), Gaps = 3/131 (2%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTL 463
R K II L+GAGISTS GIPDFRS TGLY L+ L PQ +F+IN FRQ+P F+++
Sbjct: 205 RSKNIIVLTGAGISTSLGIPDFRSKGTGLYSKLEHLGLSDPQEVFDINIFRQDPNIFYSV 264
Query: 464 AKELFPGS--FKPTISHIS*DFYMRKGSYYVIIHKTLTH*SEEPAF-PKKN*SKHTEFYT 634
A+++ P + F PT + I+ +KG + + + + P K H F T
Sbjct: 265 ARDILPNTERFSPTHAFIA--LLQQKGKLLTNYSQNIDNLEAKAGIHPDKLVQCHGSFAT 322
Query: 635 SHCLGLPQGIP 667
+ C+ +P
Sbjct: 323 ATCVKCGYKVP 333
>UniRef50_Q22ZC3 Cluster: Transcriptional regulator, Sir2 family
protein; n=1; Tetrahymena thermophila SB210|Rep:
Transcriptional regulator, Sir2 family protein -
Tetrahymena thermophila SB210
Length = 308
Score = 87.0 bits (206), Expect = 4e-16
Identities = 41/84 (48%), Positives = 56/84 (66%), Gaps = 2/84 (2%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQK-YELPQPQAIFEINFFRQNPKPFFTLA 466
K+I L+GAGIS SAGIPDFRSPETGLY ++K Y++ PQ IF I +++ NP PF +
Sbjct: 68 KQIAFLTGAGISVSAGIPDFRSPETGLYAQIKKEYDISDPQKIFSIRYYQDNPLPFMQVI 127
Query: 467 KELFPGSFKPTISH-IS*DFYMRK 535
++ F + PT +H + Y RK
Sbjct: 128 RDFFSREYHPTYAHKLIHQIYKRK 151
Score = 40.7 bits (91), Expect = 0.034
Identities = 25/70 (35%), Positives = 39/70 (55%), Gaps = 3/70 (4%)
Frame = +1
Query: 424 KFLQAKSQTFLHISKGIISRKL*AYNFTYFIRLLHE---KGLLLRHYTQNIDTLERGAGI 594
++ Q F+ + + SR+ Y+ TY +L+H+ + LL + TQNID LE GI
Sbjct: 114 RYYQDNPLPFMQVIRDFFSRE---YHPTYAHKLIHQIYKRKQLLINITQNIDGLELKTGI 170
Query: 595 PEEKLVEAHG 624
K+V+AHG
Sbjct: 171 NPSKVVQAHG 180
>UniRef50_Q4DP02 Cluster: Silent information regulator 2, putative;
n=4; Trypanosoma|Rep: Silent information regulator 2,
putative - Trypanosoma cruzi
Length = 359
Score = 86.2 bits (204), Expect = 7e-16
Identities = 39/85 (45%), Positives = 55/85 (64%), Gaps = 2/85 (2%)
Frame = +2
Query: 260 IVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQ 439
+ R+I+ + KI+ ++GAGIS +AGIPDFRSP TG+Y L KY L P F I R+
Sbjct: 20 LARYIERNNVTKILVMAGAGISVAAGIPDFRSPHTGIYARLGKYNLNSPTDAFSITLLRE 79
Query: 440 NPKPFFTLAKE--LFPGSFKPTISH 508
P F+++ +E L+PG F PT+ H
Sbjct: 80 RPDVFYSIVREMDLWPGHFWPTLVH 104
Score = 50.8 bits (116), Expect = 3e-05
Identities = 28/54 (51%), Positives = 36/54 (66%)
Frame = +1
Query: 508 YFIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHGILHITLSGIAARNTH 669
+FI+LL ++G LLR TQNID LER +G+P LVEAHG T S I R+ +
Sbjct: 105 HFIKLLADEGRLLRCCTQNIDGLERASGLPMSFLVEAHGSFS-TASCIECRSPY 157
>UniRef50_Q7QZ37 Cluster: GLP_464_19573_21615; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_464_19573_21615 - Giardia lamblia
ATCC 50803
Length = 680
Score = 85.8 bits (203), Expect = 9e-16
Identities = 37/84 (44%), Positives = 59/84 (70%), Gaps = 1/84 (1%)
Frame = +2
Query: 260 IVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQ 439
+V I + + I+ L+GAGIS +AGIPDFRS TGLY L++Y LP P ++F+++++
Sbjct: 12 LVESISRAKKESIVILAGAGISVAAGIPDFRSKGTGLYSQLERYNLPTPTSMFDLSYYCL 71
Query: 440 NPKPFFTLAKELFPG-SFKPTISH 508
P+PF +L+ +FP +KPT++H
Sbjct: 72 RPRPFSSLSVSIFPSYKYKPTMAH 95
Score = 40.3 bits (90), Expect = 0.044
Identities = 16/39 (41%), Positives = 27/39 (69%)
Frame = +1
Query: 508 YFIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
+F ++L ++GL+ YTQNID LE AG+ ++++ HG
Sbjct: 96 HFFKILEDRGLVRFIYTQNIDELEIFAGVSPRRILQCHG 134
>UniRef50_Q25337 Cluster: NAD-dependent deacetylase SIR2 homolog;
n=6; Leishmania|Rep: NAD-dependent deacetylase SIR2
homolog - Leishmania major
Length = 381
Score = 85.0 bits (201), Expect = 2e-15
Identities = 38/86 (44%), Positives = 56/86 (65%), Gaps = 2/86 (2%)
Frame = +2
Query: 257 GIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFR 436
G+ R+I+ ++I+ L GAG S +AGIPDFRS +TG+Y L KY L P F + R
Sbjct: 21 GLARYIREKDVRRILVLVGAGASVAAGIPDFRSSDTGIYAKLGKYNLDDPTDAFSLTLLR 80
Query: 437 QNPKPFFTLAKE--LFPGSFKPTISH 508
+ P+ F+++A+E L+PG F+PT H
Sbjct: 81 EKPEIFYSIARELNLWPGHFQPTAVH 106
Score = 52.4 bits (120), Expect = 1e-05
Identities = 25/39 (64%), Positives = 30/39 (76%)
Frame = +1
Query: 508 YFIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
+FIRLL ++G LLR TQNID LE+ AG+ E LVEAHG
Sbjct: 107 HFIRLLQDEGRLLRCCTQNIDGLEKAAGVSPELLVEAHG 145
>UniRef50_Q23E36 Cluster: Transcriptional regulator, Sir2 family
protein; n=1; Tetrahymena thermophila SB210|Rep:
Transcriptional regulator, Sir2 family protein -
Tetrahymena thermophila SB210
Length = 1348
Score = 84.6 bits (200), Expect = 2e-15
Identities = 41/83 (49%), Positives = 55/83 (66%)
Frame = +2
Query: 260 IVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQ 439
+V IK+ + I+ L+GAGISTS+GIPDFRSP GLY +QKY+L P+ IFEI +F +
Sbjct: 11 VVEKIKNKQINNILFLTGAGISTSSGIPDFRSPN-GLYSKVQKYKLEYPEQIFEIKYFTK 69
Query: 440 NPKPFFTLAKELFPGSFKPTISH 508
N PF+ + KE F T +H
Sbjct: 70 NQMPFYEMDKEFFSNKPHFTSAH 92
Score = 42.3 bits (95), Expect = 0.011
Identities = 22/67 (32%), Positives = 34/67 (50%)
Frame = +1
Query: 424 KFLQAKSQTFLHISKGIISRKL*AYNFTYFIRLLHEKGLLLRHYTQNIDTLERGAGIPEE 603
K+ F + K S K + YF+ ++ + LL ++QN+D LE AG+P E
Sbjct: 65 KYFTKNQMPFYEMDKEFFSNKPHFTSAHYFMAEVNRREQLLFVFSQNVDGLELEAGLPPE 124
Query: 604 KLVEAHG 624
KL + HG
Sbjct: 125 KLCQVHG 131
>UniRef50_Q0CR31 Cluster: NAD-dependent histone deacetylase SIR2;
n=2; Pezizomycotina|Rep: NAD-dependent histone
deacetylase SIR2 - Aspergillus terreus (strain NIH 2624)
Length = 1068
Score = 84.2 bits (199), Expect = 3e-15
Identities = 46/127 (36%), Positives = 69/127 (54%), Gaps = 1/127 (0%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAK 469
K I+ L+GAGISTS GIPDFRS +TGLY L+ L PQ +F+I+ FR++P FF++AK
Sbjct: 177 KNIVVLTGAGISTSLGIPDFRSKDTGLYSQLEHLGLSDPQEVFDIHVFREDPSIFFSIAK 236
Query: 470 ELFPGSFKPTISHIS*DFYMRKGSYYVIIHKTLTH-*SEEPAFPKKN*SKHTEFYTSHCL 646
++ P K + +H KG + + + + P+K H F T+ C+
Sbjct: 237 DILPTEKKYSPTHGFIRLLQDKGKLLTNYTQNIDNIEANAGVVPEKIVQCHGSFATATCV 296
Query: 647 GLPQGIP 667
+P
Sbjct: 297 KCHYKVP 303
>UniRef50_UPI0000D55B5A Cluster: PREDICTED: similar to CG5216-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG5216-PA - Tribolium castaneum
Length = 722
Score = 83.4 bits (197), Expect = 5e-15
Identities = 40/85 (47%), Positives = 59/85 (69%), Gaps = 2/85 (2%)
Frame = +2
Query: 260 IVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNL--QKYELPQPQAIFEINFF 433
+VR +K + II L+GAG+S S GIPDFRS + G+Y L +LP PQA+F+I++F
Sbjct: 204 VVRLVKG--AQNIIVLTGAGVSVSCGIPDFRSRD-GIYVRLAIDFPDLPDPQAMFDISYF 260
Query: 434 RQNPKPFFTLAKELFPGSFKPTISH 508
Q+P+PFF A++++PG F P+ H
Sbjct: 261 SQDPRPFFKFARDIYPGKFTPSPCH 285
Score = 47.6 bits (108), Expect = 3e-04
Identities = 23/38 (60%), Positives = 29/38 (76%)
Frame = +1
Query: 511 FIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
FI++L G LLR+YTQNIDTLE+ A I EK++E HG
Sbjct: 287 FIKMLENYGKLLRNYTQNIDTLEKVANI--EKVIECHG 322
>UniRef50_O96505 Cluster: SIR2; n=4; Sophophora|Rep: SIR2 -
Drosophila melanogaster (Fruit fly)
Length = 823
Score = 81.8 bits (193), Expect = 1e-14
Identities = 36/72 (50%), Positives = 54/72 (75%), Gaps = 2/72 (2%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKY--ELPQPQAIFEINFFRQNPKPFF 457
+ +KII L+GAG+S S GIPDFRS G+Y L +LP PQA+F+IN+F+++P+PF+
Sbjct: 218 KSQKIIVLTGAGVSVSCGIPDFRSTN-GIYARLAHDFPDLPDPQAMFDINYFKRDPRPFY 276
Query: 458 TLAKELFPGSFK 493
A+E++PG F+
Sbjct: 277 KFAREIYPGEFQ 288
Score = 51.2 bits (117), Expect = 2e-05
Identities = 24/38 (63%), Positives = 31/38 (81%)
Frame = +1
Query: 511 FIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
FI++L KG LLR+YTQNIDTLER AGI ++++E HG
Sbjct: 297 FIKMLETKGKLLRNYTQNIDTLERVAGI--QRVIECHG 332
>UniRef50_A2Q9C4 Cluster: Contig An01c0250, complete genome; n=18;
Pezizomycotina|Rep: Contig An01c0250, complete genome -
Aspergillus niger
Length = 495
Score = 81.8 bits (193), Expect = 1e-14
Identities = 39/76 (51%), Positives = 51/76 (67%), Gaps = 2/76 (2%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAK 469
K I+ L+GAGISTS GIPDFRS +TGLY L L PQ +F+I FR++P FF++AK
Sbjct: 179 KNIVVLTGAGISTSLGIPDFRSKDTGLYSQLAHLGLSDPQEVFDIQVFREDPSIFFSIAK 238
Query: 470 ELFP--GSFKPTISHI 511
++ P F PT + I
Sbjct: 239 DILPTEKKFSPTHAFI 254
Score = 50.4 bits (115), Expect = 4e-05
Identities = 25/58 (43%), Positives = 35/58 (60%)
Frame = +1
Query: 451 FLHISKGIISRKL*AYNFTYFIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
F I+K I+ + FIR+L +KG LL +YTQNID +E AG+ E +V+ HG
Sbjct: 233 FFSIAKDILPTEKKFSPTHAFIRVLQDKGKLLTNYTQNIDNIEANAGVLPENIVQCHG 290
>UniRef50_A0C2R2 Cluster: Chromosome undetermined scaffold_145,
whole genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_145,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 258
Score = 79.0 bits (186), Expect = 1e-13
Identities = 34/85 (40%), Positives = 58/85 (68%), Gaps = 2/85 (2%)
Frame = +2
Query: 260 IVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQ 439
++R +K+ KKI +GAGIS +AG+ D+RS +TGLY L+K+ L P+ +++IN FR+
Sbjct: 8 LIRKLKAKEFKKITIAAGAGISVAAGLSDYRSKDTGLYDQLKKFNLSNPEQVYDINVFRK 67
Query: 440 NPKPFFTLAKELFPGS--FKPTISH 508
NP +++++KE + +PT +H
Sbjct: 68 NPSLYYSVSKEFGTHNLDLQPTFAH 92
Score = 37.1 bits (82), Expect = 0.41
Identities = 18/38 (47%), Positives = 23/38 (60%)
Frame = +1
Query: 511 FIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
FI L LL +TQNID LE AG+ E K+++ HG
Sbjct: 94 FIYHLDRNDQLLNCFTQNIDGLELVAGVRESKVIQVHG 131
>UniRef50_Q4PG00 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 596
Score = 77.0 bits (181), Expect = 4e-13
Identities = 38/76 (50%), Positives = 52/76 (68%), Gaps = 3/76 (3%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQ---KYELPQPQAIFEINFFRQNPKPFFT 460
K+I+ LSGAGIS S GIPDFRS + G+Y LQ +YEL PQ +F+ FF NP F++
Sbjct: 191 KRIMILSGAGISVSCGIPDFRSKD-GIYAILQSEGQYELDDPQDMFDKTFFLSNPSMFYS 249
Query: 461 LAKELFPGSFKPTISH 508
A ++FP +F P+ +H
Sbjct: 250 FAHKIFPSNFVPSSAH 265
Score = 46.4 bits (105), Expect = 7e-04
Identities = 21/38 (55%), Positives = 31/38 (81%)
Frame = +1
Query: 511 FIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
FI+L+ E+G LLR+Y+QNIDTLE+ GI E++++ HG
Sbjct: 267 FIKLIEERGQLLRNYSQNIDTLEQLVGI--ERVLQCHG 302
>UniRef50_A7EMW8 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 533
Score = 74.5 bits (175), Expect = 2e-12
Identities = 38/72 (52%), Positives = 47/72 (65%), Gaps = 2/72 (2%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAK 469
KKII ++GAGISTS GIPDFRS GLY L+ L PQ +F I+ FR++P FF +AK
Sbjct: 208 KKIIVITGAGISTSLGIPDFRSAN-GLYAQLEDTGLSDPQEVFNIDLFREDPTIFFQIAK 266
Query: 470 ELFPG--SFKPT 499
+ P F PT
Sbjct: 267 NILPSVVRFSPT 278
Score = 49.2 bits (112), Expect = 1e-04
Identities = 24/58 (41%), Positives = 35/58 (60%)
Frame = +1
Query: 451 FLHISKGIISRKL*AYNFTYFIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
F I+K I+ + FI++L +KG LL +YTQNID +E AGI E +++ HG
Sbjct: 261 FFQIAKNILPSVVRFSPTHQFIKVLQDKGKLLTNYTQNIDGIESAAGILPENVIQCHG 318
>UniRef50_A2F8E1 Cluster: Transcriptional regulator, Sir2 family
protein; n=1; Trichomonas vaginalis G3|Rep:
Transcriptional regulator, Sir2 family protein -
Trichomonas vaginalis G3
Length = 331
Score = 72.5 bits (170), Expect = 9e-12
Identities = 46/145 (31%), Positives = 69/145 (47%), Gaps = 6/145 (4%)
Frame = +2
Query: 272 IKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQ---KYELPQPQAIFEINFFRQN 442
I S K +I L+GAGIST+AGIPDFRSP G+Y L+ + + P +F+I+ F +
Sbjct: 14 IISGNYKNVIVLTGAGISTAAGIPDFRSPAIGIYATLKSASRLKFRDPTFVFDIDVFMDD 73
Query: 443 PKPFFTLAKELFPGSF--KPTISHIS*DFYMRKGSYYVIIHKTLTH*SEEPAFPK-KN*S 613
PKPF+ + L+P +PT H + + G + + + P+ K
Sbjct: 74 PKPFWWIFSHLWPKDLWPRPTEMHYFIGYLNQLGVLKRVYTQNVDGLEIPGGLPEDKLVQ 133
Query: 614 KHTEFYTSHCLGLPQGIPTGVCQRK 688
H T HC +P C R+
Sbjct: 134 CHGALPTCHCCDCHAAVPLAECLRQ 158
Score = 51.6 bits (118), Expect = 2e-05
Identities = 23/41 (56%), Positives = 30/41 (73%)
Frame = +1
Query: 508 YFIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHGIL 630
YFI L++ G+L R YTQN+D LE G+PE+KLV+ HG L
Sbjct: 98 YFIGYLNQLGVLKRVYTQNVDGLEIPGGLPEDKLVQCHGAL 138
>UniRef50_A7TQE2 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 602
Score = 71.7 bits (168), Expect = 2e-11
Identities = 35/69 (50%), Positives = 43/69 (62%)
Frame = +2
Query: 275 KSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPF 454
K KKII L+GAGISTS GIPDFRS E G Y L+ L PQ +F + FR+NP F
Sbjct: 262 KLKSAKKIIVLTGAGISTSLGIPDFRSSE-GFYSKLRNLGLDDPQDVFNLQIFRENPSVF 320
Query: 455 FTLAKELFP 481
+ +A + P
Sbjct: 321 YNIAYMVLP 329
Score = 51.6 bits (118), Expect = 2e-05
Identities = 23/38 (60%), Positives = 29/38 (76%)
Frame = +1
Query: 511 FIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
F++LL +K LLR+YTQNID LE AGI EK+V+ HG
Sbjct: 340 FLKLLQDKDKLLRNYTQNIDNLESYAGIKPEKMVQCHG 377
>UniRef50_Q0UNC9 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 479
Score = 70.9 bits (166), Expect = 3e-11
Identities = 32/73 (43%), Positives = 48/73 (65%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAK 469
K I+ ++GAGISTS GIPDFRS TG Y L + +P+ +F+I+ F ++P+ F+ LA
Sbjct: 174 KNIMIITGAGISTSLGIPDFRSKNTGFYSRLLQMGYEEPEQVFDIHNFDEDPRTFYALAG 233
Query: 470 ELFPGSFKPTISH 508
++ P K T +H
Sbjct: 234 DIIPDLEKWTPTH 246
Score = 50.0 bits (114), Expect = 5e-05
Identities = 22/38 (57%), Positives = 29/38 (76%)
Frame = +1
Query: 511 FIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
FIRLL +K LL +YTQNID +E AGI ++KL++ HG
Sbjct: 248 FIRLLQDKEKLLTNYTQNIDNVEANAGILKDKLIQCHG 285
>UniRef50_Q6BPH5 Cluster: Debaryomyces hansenii chromosome E of
strain CBS767 of Debaryomyces hansenii; n=2;
Saccharomycetaceae|Rep: Debaryomyces hansenii chromosome
E of strain CBS767 of Debaryomyces hansenii -
Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
Length = 573
Score = 70.1 bits (164), Expect = 5e-11
Identities = 41/122 (33%), Positives = 60/122 (49%), Gaps = 1/122 (0%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTL 463
+ KKI+ ++GAGISTS GIPDFRS + G Y LQ L PQ +F+++FF +P F+ +
Sbjct: 259 KAKKILVVTGAGISTSLGIPDFRSSK-GFYSQLQYLGLSDPQEVFDLDFFHSDPNIFYLI 317
Query: 464 AKELFPGSFKPTISHIS*DFYMRKGSYYVIIHKTLTH*SEEPAF-PKKN*SKHTEFYTSH 640
A + P T H KG + + + P+K H F T+
Sbjct: 318 AYMILPPEKSYTPLHAFIKLLQNKGKLLRNYTQNIDNLESNVGIKPEKLIQCHGSFATAS 377
Query: 641 CL 646
C+
Sbjct: 378 CV 379
Score = 54.4 bits (125), Expect = 3e-06
Identities = 24/38 (63%), Positives = 28/38 (73%)
Frame = +1
Query: 511 FIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
FI+LL KG LLR+YTQNID LE GI EKL++ HG
Sbjct: 334 FIKLLQNKGKLLRNYTQNIDNLESNVGIKPEKLIQCHG 371
>UniRef50_O94640 Cluster: NAD-dependent histone deacetylase sir2;
n=1; Schizosaccharomyces pombe|Rep: NAD-dependent
histone deacetylase sir2 - Schizosaccharomyces pombe
(Fission yeast)
Length = 475
Score = 70.1 bits (164), Expect = 5e-11
Identities = 33/75 (44%), Positives = 50/75 (66%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTL 463
+ K ++ L GAGISTS GI DFRS + G Y L ++ L +P +F+I+ FR+NP+ F+T
Sbjct: 155 KAKNVVVLVGAGISTSLGILDFRS-DNGFYARLARHGLSEPSEMFDIHTFRENPEIFYTF 213
Query: 464 AKELFPGSFKPTISH 508
A++L P + + SH
Sbjct: 214 ARDLLPETNHYSPSH 228
Score = 43.6 bits (98), Expect = 0.005
Identities = 18/38 (47%), Positives = 26/38 (68%)
Frame = +1
Query: 511 FIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
FIRLL +K L +TQNID LE+ G+ + K+++ HG
Sbjct: 230 FIRLLEKKNKLSTLFTQNIDNLEKKTGLSDNKIIQCHG 267
>UniRef50_O59923 Cluster: NAD-dependent histone deacetylase SIR2;
n=3; Candida albicans|Rep: NAD-dependent histone
deacetylase SIR2 - Candida albicans (Yeast)
Length = 515
Score = 68.9 bits (161), Expect = 1e-10
Identities = 34/75 (45%), Positives = 49/75 (65%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTL 463
R KKI+ ++GAGISTS GIPDFRS + GLY+ L K L PQ +F++ F + + F+T+
Sbjct: 233 RAKKIMVVTGAGISTSLGIPDFRSFK-GLYNQLSKLNLSDPQKVFDLQTFMREGRLFYTI 291
Query: 464 AKELFPGSFKPTISH 508
A + P K ++ H
Sbjct: 292 AHLVLPPDGKFSLLH 306
Score = 52.8 bits (121), Expect = 8e-06
Identities = 23/38 (60%), Positives = 30/38 (78%)
Frame = +1
Query: 511 FIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
F++LL +K LLR+YTQNID LE+ AG+ EKLV+ HG
Sbjct: 308 FLKLLQDKHKLLRNYTQNIDNLEQRAGLKSEKLVQCHG 345
>UniRef50_A6RRE3 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 526
Score = 68.1 bits (159), Expect = 2e-10
Identities = 38/77 (49%), Positives = 46/77 (59%), Gaps = 2/77 (2%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAK 469
KKII ++GAGISTS GIPDFRS GLY L PQ IF I F+++P FF +AK
Sbjct: 204 KKIIVITGAGISTSLGIPDFRS-ANGLYAQFGHLNLNDPQEIFNIEKFKEDPSIFFGVAK 262
Query: 470 ELFP--GSFKPTISHIS 514
+ P F PT I+
Sbjct: 263 VILPEIRRFSPTHQFIA 279
Score = 44.8 bits (101), Expect = 0.002
Identities = 20/38 (52%), Positives = 25/38 (65%)
Frame = +1
Query: 511 FIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
FI LL G LL +YTQNID +E AGI +K++ HG
Sbjct: 277 FIALLQAHGKLLTNYTQNIDNIESMAGISPDKIIHCHG 314
>UniRef50_A5DJ74 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 522
Score = 66.5 bits (155), Expect = 6e-10
Identities = 33/73 (45%), Positives = 43/73 (58%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAK 469
KKI+ LSGAGISTS GIPDFRS + G Y L+ L PQ +F++ F +P F+ +A
Sbjct: 210 KKILVLSGAGISTSLGIPDFRSSQ-GFYAKLEHLGLSDPQDVFDLGIFHTDPTVFYLIAH 268
Query: 470 ELFPGSFKPTISH 508
+ P T H
Sbjct: 269 MILPPEHSFTPMH 281
Score = 52.8 bits (121), Expect = 8e-06
Identities = 24/52 (46%), Positives = 35/52 (67%)
Frame = +1
Query: 511 FIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHGILHITLSGIAARNT 666
FI+ L +KG+LLR+YTQNID LE GI +++V+ HG T + + +NT
Sbjct: 283 FIKTLDDKGILLRNYTQNIDNLESNVGINSDRVVQCHGSF-ATATCVTCKNT 333
>UniRef50_A3LN35 Cluster: NAD-dependent histone deacetylase SIR2;
n=1; Pichia stipitis|Rep: NAD-dependent histone
deacetylase SIR2 - Pichia stipitis (Yeast)
Length = 391
Score = 66.1 bits (154), Expect = 8e-10
Identities = 32/73 (43%), Positives = 49/73 (67%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAK 469
KKI+ +SGAGISTS GIPDFRS + GLY L+ L PQ +F++ F+++P F+++A
Sbjct: 111 KKIMVISGAGISTSLGIPDFRSFK-GLYAQLEHLNLKDPQKVFDMGAFQKDPSIFYSIAH 169
Query: 470 ELFPGSFKPTISH 508
+ P + ++ H
Sbjct: 170 LVLPPEGRFSMLH 182
Score = 52.8 bits (121), Expect = 8e-06
Identities = 23/38 (60%), Positives = 29/38 (76%)
Frame = +1
Query: 511 FIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
FI+LL +KG LLR+YTQNID LE GI +KL++ HG
Sbjct: 184 FIKLLQDKGKLLRNYTQNIDNLESRVGIHPDKLIQCHG 221
>UniRef50_P06700 Cluster: NAD-dependent histone deacetylase SIR2;
n=13; Saccharomycetales|Rep: NAD-dependent histone
deacetylase SIR2 - Saccharomyces cerevisiae (Baker's
yeast)
Length = 562
Score = 64.9 bits (151), Expect = 2e-09
Identities = 30/69 (43%), Positives = 41/69 (59%)
Frame = +2
Query: 275 KSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPF 454
K +KI+ L+GAG+STS GIPDFRS E G Y ++ L PQ +F N F +P F
Sbjct: 250 KLHTARKILVLTGAGVSTSLGIPDFRSSE-GFYSKIKHLGLDDPQDVFNYNIFMHDPSVF 308
Query: 455 FTLAKELFP 481
+ +A + P
Sbjct: 309 YNIANMVLP 317
Score = 53.2 bits (122), Expect = 6e-06
Identities = 27/56 (48%), Positives = 35/56 (62%)
Frame = +1
Query: 511 FIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHGILHITLSGIAARNTHWSL 678
FI++L KG LLR+YTQNID LE AGI +KLV+ HG + + HW+L
Sbjct: 328 FIKMLQMKGKLLRNYTQNIDNLESYAGISTDKLVQCHG----SFATATCVTCHWNL 379
>UniRef50_Q3A6W7 Cluster: NAD-dependent protein deacetylases, SIR2
family; n=2; Pelobacter|Rep: NAD-dependent protein
deacetylases, SIR2 family - Pelobacter carbinolicus
(strain DSM 2380 / Gra Bd 1)
Length = 278
Score = 64.1 bits (149), Expect = 3e-09
Identities = 34/89 (38%), Positives = 56/89 (62%), Gaps = 2/89 (2%)
Frame = +2
Query: 248 QPYGIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEIN 427
+P I+ RC ++TLSGAGIST+AGIPDFR P+ GLY ++Y+ P+ +F+I+
Sbjct: 21 EPARCADMIRRSRC--VVTLSGAGISTAAGIPDFRGPQ-GLYVT-RRYD---PEKVFDID 73
Query: 428 FFRQNPKPFFTLAKELFP--GSFKPTISH 508
+F + P+ F+ ++ + +PT +H
Sbjct: 74 WFHREPRYFYEFTRDFVSTVKAIRPTFTH 102
>UniRef50_Q875P9 Cluster: HST1; n=1; Lachancea kluyveri|Rep: HST1 -
Saccharomyces kluyveri (Yeast) (Saccharomyces
silvestris)
Length = 414
Score = 63.3 bits (147), Expect = 6e-09
Identities = 29/69 (42%), Positives = 42/69 (60%)
Frame = +2
Query: 275 KSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPF 454
K ++++ L+GAGISTS GIPDFRS E G Y ++ L PQ +F + F Q+P F
Sbjct: 79 KLKTARRVLVLTGAGISTSLGIPDFRSSE-GFYSKIKHLGLDDPQDVFNYDIFMQDPSVF 137
Query: 455 FTLAKELFP 481
+ +A + P
Sbjct: 138 YNIAHMVLP 146
Score = 55.6 bits (128), Expect = 1e-06
Identities = 27/56 (48%), Positives = 36/56 (64%)
Frame = +1
Query: 511 FIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHGILHITLSGIAARNTHWSL 678
FIR++ +KG LLR+YTQNID LE AGI EK+V+ HG + + + HW L
Sbjct: 157 FIRMIQDKGKLLRNYTQNIDNLESYAGIQAEKMVQCHG----SFATASCVTCHWKL 208
>UniRef50_Q5AQ47 Cluster: Potential Sir2 family histone deacetylase;
n=2; Candida albicans|Rep: Potential Sir2 family histone
deacetylase - Candida albicans (Yeast)
Length = 657
Score = 62.9 bits (146), Expect = 7e-09
Identities = 28/67 (41%), Positives = 43/67 (64%)
Frame = +2
Query: 281 DRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFT 460
+ K I+ ++GAGISTS GIPDFRS + G Y +Q L PQ +F+++ F +P F++
Sbjct: 299 ENSKNIMVITGAGISTSLGIPDFRSSQ-GFYSMIQHLGLSDPQEVFDLDLFLNDPNIFYS 357
Query: 461 LAKELFP 481
+A + P
Sbjct: 358 IAHMILP 364
Score = 51.6 bits (118), Expect = 2e-05
Identities = 23/38 (60%), Positives = 29/38 (76%)
Frame = +1
Query: 511 FIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
FI+LL +K LLR+YTQNID LE AGI +E L++ HG
Sbjct: 375 FIKLLQDKNKLLRNYTQNIDNLESYAGIHKENLIQCHG 412
>UniRef50_A5DSX8 Cluster: NAD-dependent histone deacetylase SIR2;
n=1; Lodderomyces elongisporus NRRL YB-4239|Rep:
NAD-dependent histone deacetylase SIR2 - Lodderomyces
elongisporus (Yeast) (Saccharomyces elongisporus)
Length = 568
Score = 62.9 bits (146), Expect = 7e-09
Identities = 32/75 (42%), Positives = 46/75 (61%), Gaps = 2/75 (2%)
Frame = +2
Query: 293 KIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAKE 472
KI+ ++GAGISTS GIPDFRS + G Y +Q L PQ +F++ F +P F+++A
Sbjct: 258 KILVITGAGISTSLGIPDFRSSQ-GFYSMVQHLGLSDPQEVFDLLIFNSDPSLFYSIAHM 316
Query: 473 LFP--GSFKPTISHI 511
+ P +F P S I
Sbjct: 317 VLPPENTFSPLHSFI 331
Score = 56.0 bits (129), Expect = 8e-07
Identities = 29/52 (55%), Positives = 35/52 (67%)
Frame = +1
Query: 511 FIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHGILHITLSGIAARNT 666
FI LL +KG LLR+YTQNID LE AGI EK+V+ HG T + + RNT
Sbjct: 330 FIYLLQQKGKLLRNYTQNIDNLESYAGIVPEKMVQCHGSF-ATATCVTCRNT 380
>UniRef50_A5DNV7 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 403
Score = 62.1 bits (144), Expect = 1e-08
Identities = 31/76 (40%), Positives = 48/76 (63%)
Frame = +2
Query: 281 DRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFT 460
++ KKI+ ++GAGISTS GIPDFRS + G+Y L + L Q +F I+ F ++P F+
Sbjct: 114 EKAKKILVVTGAGISTSLGIPDFRSFQ-GIYSQLSRSGLENAQQVFHIDRFCKDPTLFYL 172
Query: 461 LAKELFPGSFKPTISH 508
+A ++ P K + H
Sbjct: 173 VAHKILPQGDKVSDFH 188
Score = 50.8 bits (116), Expect = 3e-05
Identities = 24/44 (54%), Positives = 29/44 (65%)
Frame = +1
Query: 499 NFTYFIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHGIL 630
+F F+RLL +K LLR YTQNID LE AGI ++V HG L
Sbjct: 186 DFHRFLRLLEQKNKLLRVYTQNIDNLELAAGIDPSRIVHCHGTL 229
>UniRef50_Q6C219 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 320
Score = 61.7 bits (143), Expect = 2e-08
Identities = 30/67 (44%), Positives = 44/67 (65%), Gaps = 2/67 (2%)
Frame = +2
Query: 281 DRCKKIITLSGAGISTSAGIPDFRSPETGLYH--NLQKYELPQPQAIFEINFFRQNPKPF 454
+ + I+ L GAGISTS GIPDFRS + GLY +L+ L PQ +F++ F Q+P PF
Sbjct: 58 ETAQNIVVLCGAGISTSLGIPDFRSAD-GLYKSLDLESLGLSDPQEVFDLEVFDQDPTPF 116
Query: 455 FTLAKEL 475
+ +A ++
Sbjct: 117 YRVASKV 123
Score = 56.0 bits (129), Expect = 8e-07
Identities = 25/42 (59%), Positives = 31/42 (73%)
Frame = +1
Query: 511 FIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHGILHI 636
F++LL +KG LLR YTQNID LE AGI E K+V+ HG H+
Sbjct: 137 FLKLLQDKGKLLRIYTQNIDDLEHIAGIEESKMVQCHGAFHM 178
>UniRef50_Q9WYW0 Cluster: NAD-dependent deacetylase; n=4;
Thermotoga|Rep: NAD-dependent deacetylase - Thermotoga
maritima
Length = 246
Score = 60.9 bits (141), Expect = 3e-08
Identities = 34/73 (46%), Positives = 49/73 (67%), Gaps = 2/73 (2%)
Frame = +2
Query: 299 ITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAKE-L 475
+TL+GAGIST +GIPDFR P G+Y +KY Q +F+I+FF +P+ F+ AKE +
Sbjct: 17 VTLTGAGISTPSGIPDFRGP-NGIY---KKYS----QNVFDIDFFYSHPEEFYRFAKEGI 68
Query: 476 FPG-SFKPTISHI 511
FP KP ++H+
Sbjct: 69 FPMLQAKPNLAHV 81
Score = 32.7 bits (71), Expect = 8.9
Identities = 17/34 (50%), Positives = 22/34 (64%)
Frame = +1
Query: 523 LHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
L EKGL+ TQNID L + AG +K++E HG
Sbjct: 86 LEEKGLIEAVITQNIDRLHQRAG--SKKVIELHG 117
>UniRef50_A6P1S7 Cluster: Putative uncharacterized protein; n=2;
Bacteria|Rep: Putative uncharacterized protein -
Bacteroides capillosus ATCC 29799
Length = 262
Score = 58.8 bits (136), Expect = 1e-07
Identities = 35/83 (42%), Positives = 49/83 (59%), Gaps = 2/83 (2%)
Frame = +2
Query: 266 RWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNP 445
RWI D +I+ GAG+ST +GIPDFRS + GLY+ Q+Y+ P P+ I F+ P
Sbjct: 30 RWI--DESSRIVFFGGAGVSTESGIPDFRSVD-GLYN--QQYDYP-PETILSHTFYEARP 83
Query: 446 KPFFTL--AKELFPGSFKPTISH 508
+ FF K LFP + +P +H
Sbjct: 84 EEFFRFYRNKMLFPDA-QPNAAH 105
>UniRef50_Q0AY57 Cluster: Regulatory protein, sir2 family; n=1;
Syntrophomonas wolfei subsp. wolfei str. Goettingen|Rep:
Regulatory protein, sir2 family - Syntrophomonas wolfei
subsp. wolfei (strain Goettingen)
Length = 253
Score = 57.6 bits (133), Expect = 3e-07
Identities = 29/66 (43%), Positives = 39/66 (59%)
Frame = +2
Query: 281 DRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFT 460
DR + ++GAGIST AGIPDFR PE G+Y L + + I I+FFR NP F+
Sbjct: 13 DRSHNTVVVTGAGISTEAGIPDFRGPE-GIYRKLGENRV---MKIINIDFFRNNPLEFYK 68
Query: 461 LAKELF 478
++ F
Sbjct: 69 FYRQYF 74
>UniRef50_A4M603 Cluster: Silent information regulator protein Sir2;
n=1; Petrotoga mobilis SJ95|Rep: Silent information
regulator protein Sir2 - Petrotoga mobilis SJ95
Length = 256
Score = 54.4 bits (125), Expect = 3e-06
Identities = 29/73 (39%), Positives = 44/73 (60%), Gaps = 2/73 (2%)
Frame = +2
Query: 296 IITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAKEL 475
I LSGAG+ST+AGIPDFR P G+Y K + P+ IF++++F +P F+ K+
Sbjct: 18 IAVLSGAGMSTNAGIPDFRGP-NGIY---TKANIENPERIFDLDYFYLDPSLFYKFHKKF 73
Query: 476 --FPGSFKPTISH 508
+ +PT +H
Sbjct: 74 LEYITKAEPTFTH 86
>UniRef50_A2DKY5 Cluster: Transcriptional regulator, Sir2 family
protein; n=1; Trichomonas vaginalis G3|Rep:
Transcriptional regulator, Sir2 family protein -
Trichomonas vaginalis G3
Length = 180
Score = 54.0 bits (124), Expect = 3e-06
Identities = 26/78 (33%), Positives = 43/78 (55%), Gaps = 3/78 (3%)
Frame = +2
Query: 272 IKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQ---PQAIFEINFFRQN 442
+KS K ++ ++G+GI + GIPD S L ++ P +F+I FFR+N
Sbjct: 12 LKSGNYKNVVVMTGSGICNACGIPDLHSIIPDLNKKAEETGFTPYMTPPFVFDIRFFREN 71
Query: 443 PKPFFTLAKELFPGSFKP 496
PKPF+ + E++P + P
Sbjct: 72 PKPFWWVFSEIWPWNEMP 89
Score = 39.5 bits (88), Expect = 0.078
Identities = 20/42 (47%), Positives = 25/42 (59%)
Frame = +1
Query: 499 NFTYFIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
+F IRL+ E GLL R YT N D LE A + K+V+ HG
Sbjct: 93 DFHILIRLIEEMGLLRRWYTTNTDCLELDAIKDKSKVVQCHG 134
>UniRef50_A6LP94 Cluster: Silent information regulator protein Sir2;
n=1; Thermosipho melanesiensis BI429|Rep: Silent
information regulator protein Sir2 - Thermosipho
melanesiensis BI429
Length = 234
Score = 53.6 bits (123), Expect = 4e-06
Identities = 31/66 (46%), Positives = 40/66 (60%)
Frame = +2
Query: 296 IITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAKEL 475
++ L+GAGISTS+GIPDFRS E GLY YEL F FF+ +P F+ K+
Sbjct: 14 VVALTGAGISTSSGIPDFRS-EDGLYKE-YGYEL------FSYEFFKNHPDIFYEYIKKE 65
Query: 476 FPGSFK 493
FP +K
Sbjct: 66 FPKMYK 71
>UniRef50_A4J646 Cluster: Silent information regulator protein Sir2;
n=2; Peptococcaceae|Rep: Silent information regulator
protein Sir2 - Desulfotomaculum reducens MI-1
Length = 256
Score = 52.8 bits (121), Expect = 8e-06
Identities = 27/57 (47%), Positives = 38/57 (66%)
Frame = +2
Query: 293 KIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTL 463
K I L+GAGIST +GIPDFRS TGL++ +Y+ PQ + I ++NP+ F+ L
Sbjct: 19 KTIALTGAGISTESGIPDFRSKNTGLWN---QYD---PQEVASIQALKKNPESFYAL 69
>UniRef50_A7HL19 Cluster: Silent information regulator protein Sir2;
n=1; Fervidobacterium nodosum Rt17-B1|Rep: Silent
information regulator protein Sir2 - Fervidobacterium
nodosum Rt17-B1
Length = 244
Score = 51.6 bits (118), Expect = 2e-05
Identities = 29/71 (40%), Positives = 44/71 (61%)
Frame = +2
Query: 260 IVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQ 439
+V W+K+ + ++T GAG+S +GIPDFRS + G+Y K+ Q IF+I+ F Q
Sbjct: 7 LVSWLKNSKFTTVLT--GAGVSVPSGIPDFRS-KNGVY---SKW----GQEIFDIDLFHQ 56
Query: 440 NPKPFFTLAKE 472
NP F+ AK+
Sbjct: 57 NPDRFYEFAKQ 67
>UniRef50_Q839C6 Cluster: NAD-dependent deacetylase; n=14;
Bacilli|Rep: NAD-dependent deacetylase - Enterococcus
faecalis (Streptococcus faecalis)
Length = 237
Score = 51.2 bits (117), Expect = 2e-05
Identities = 27/82 (32%), Positives = 46/82 (56%)
Frame = +2
Query: 263 VRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQN 442
+ W+ + + KI L+GAGIST++G+PD+RS + G+Y +Q QP+ + +
Sbjct: 10 IHWLATQQ--KITFLTGAGISTASGVPDYRSLK-GVYQGIQ-----QPEYLLSRTCLKTE 61
Query: 443 PKPFFTLAKELFPGSFKPTISH 508
P+ F+ K L+ +P I H
Sbjct: 62 PEKFYQFVKTLYHPDAQPNIIH 83
>UniRef50_Q8R984 Cluster: NAD-dependent deacetylase 2; n=1;
Thermoanaerobacter tengcongensis|Rep: NAD-dependent
deacetylase 2 - Thermoanaerobacter tengcongensis
Length = 250
Score = 51.2 bits (117), Expect = 2e-05
Identities = 22/43 (51%), Positives = 31/43 (72%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIF 418
+K + L+GAGIST +GIPDFRSP TGL+ N+ E+ + +F
Sbjct: 21 QKTMVLTGAGISTESGIPDFRSPGTGLWENMDPTEVLSTKVLF 63
>UniRef50_Q6BPA4 Cluster: Debaryomyces hansenii chromosome E of
strain CBS767 of Debaryomyces hansenii; n=6;
Saccharomycetales|Rep: Debaryomyces hansenii chromosome
E of strain CBS767 of Debaryomyces hansenii -
Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
Length = 438
Score = 50.4 bits (115), Expect = 4e-05
Identities = 34/83 (40%), Positives = 49/83 (59%), Gaps = 8/83 (9%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQP----QAIFEINFFRQNP-- 445
+ +K + L+GAGIS +AGIPDFRS + GLY N+ K + P+ Q +F+I+ FR
Sbjct: 27 KSRKAVVLTGAGISCNAGIPDFRSSD-GLY-NMVKSKFPKKIVKGQDLFDISIFRDEVTL 84
Query: 446 KPFFTLAKELFPGSF--KPTISH 508
F T + L+ S KPT +H
Sbjct: 85 SLFCTFMESLYLSSIDAKPTETH 107
Score = 33.5 bits (73), Expect = 5.1
Identities = 16/23 (69%), Positives = 18/23 (78%)
Frame = +1
Query: 511 FIRLLHEKGLLLRHYTQNIDTLE 579
FI++L EK LLR YTQNID LE
Sbjct: 109 FIKILKEKKKLLRCYTQNIDGLE 131
>UniRef50_Q97MB4 Cluster: NAD-dependent deacetylase; n=7;
Bacteria|Rep: NAD-dependent deacetylase - Clostridium
acetobutylicum
Length = 245
Score = 50.4 bits (115), Expect = 4e-05
Identities = 27/74 (36%), Positives = 39/74 (52%), Gaps = 1/74 (1%)
Frame = +2
Query: 296 IITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAKE- 472
I+ GAG+ST + IPDFRS E GLY + P P+ + FF+ + + FF +E
Sbjct: 20 IVFFGGAGVSTESNIPDFRS-ENGLYKTKNNFSYP-PEVMLSHTFFKNHTEDFFEFYREK 77
Query: 473 LFPGSFKPTISHIS 514
+ KP +H S
Sbjct: 78 MIFKDAKPNAAHYS 91
>UniRef50_Q899G3 Cluster: NAD-dependent deacetylase; n=19; cellular
organisms|Rep: NAD-dependent deacetylase - Clostridium
tetani
Length = 247
Score = 50.0 bits (114), Expect = 5e-05
Identities = 26/72 (36%), Positives = 40/72 (55%), Gaps = 1/72 (1%)
Frame = +2
Query: 296 IITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAKEL 475
I+ GAG+ST + IPDFRS E GLY + P+ + +FF+++ + FF KE
Sbjct: 17 IVFFGGAGVSTESNIPDFRS-EEGLYKTKSNFSY-SPEVMLSHSFFKEHTEDFFDFYKEK 74
Query: 476 FPGSF-KPTISH 508
+ KP ++H
Sbjct: 75 MIYKYAKPNLAH 86
>UniRef50_A6DC77 Cluster: Silent information regulator protein Sir2;
n=1; Caminibacter mediatlanticus TB-2|Rep: Silent
information regulator protein Sir2 - Caminibacter
mediatlanticus TB-2
Length = 243
Score = 49.6 bits (113), Expect = 7e-05
Identities = 29/63 (46%), Positives = 40/63 (63%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAK 469
K ++ +GAGIS +GIP FR P TGL+ KY+ P+ I +I+FF QNPK + K
Sbjct: 15 KNLVAFTGAGISVESGIPTFRGP-TGLW---SKYD-PK---ILDIDFFIQNPKESWKYIK 66
Query: 470 ELF 478
E+F
Sbjct: 67 EIF 69
Score = 33.5 bits (73), Expect = 5.1
Identities = 17/39 (43%), Positives = 24/39 (61%)
Frame = +1
Query: 508 YFIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
YF+ L +KG+L TQNID L + AG + ++E HG
Sbjct: 83 YFLADLEKKGILKAVITQNIDNLHQKAG--SKNVIEFHG 119
>UniRef50_Q5KPC9 Cluster: Hst3 protein, putative; n=2;
Filobasidiella neoformans|Rep: Hst3 protein, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 389
Score = 49.6 bits (113), Expect = 7e-05
Identities = 35/83 (42%), Positives = 49/83 (59%), Gaps = 8/83 (9%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQP----QAIFEINFFR--QNP 445
+ ++I+T+SGAGIS S+GIPDFRS E GLY +L K + P + +F F Q+
Sbjct: 34 KARRIVTVSGAGISCSSGIPDFRS-EGGLY-SLVKEKYPDAFFTGKDLFSAGTFANPQST 91
Query: 446 KPFFTLAKELFP--GSFKPTISH 508
F+T ELF S +PT +H
Sbjct: 92 SIFYTFIAELFHCCASAQPTRTH 114
Score = 39.5 bits (88), Expect = 0.078
Identities = 18/29 (62%), Positives = 21/29 (72%)
Frame = +1
Query: 508 YFIRLLHEKGLLLRHYTQNIDTLERGAGI 594
+FIR L +KG LLR YTQNID ER G+
Sbjct: 115 HFIRKLEQKGKLLRSYTQNIDGFERRMGL 143
>UniRef50_Q54LF0 Cluster: Ankyrin repeat-containing protein; n=1;
Dictyostelium discoideum AX4|Rep: Ankyrin
repeat-containing protein - Dictyostelium discoideum AX4
Length = 778
Score = 49.2 bits (112), Expect = 1e-04
Identities = 22/40 (55%), Positives = 29/40 (72%), Gaps = 1/40 (2%)
Frame = +1
Query: 508 YFIRLLHEK-GLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
YFI L+EK G LLR+YTQN+D L+ G P +K++ AHG
Sbjct: 570 YFINDLNEKYGCLLRNYTQNVDPLQERTGTPTDKIIHAHG 609
Score = 39.9 bits (89), Expect = 0.059
Identities = 19/42 (45%), Positives = 26/42 (61%)
Frame = +2
Query: 260 IVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQ 385
++ IK K +I LSGAGIS +AGIP +R+ + L N Q
Sbjct: 479 VINGIKKGEFKNVIVLSGAGISANAGIPPYRTKDGLLAKNKQ 520
>UniRef50_Q4WT50 Cluster: SIR2 family histone deacetylase (Hst4),
putative; n=7; Trichocomaceae|Rep: SIR2 family histone
deacetylase (Hst4), putative - Aspergillus fumigatus
(Sartorya fumigata)
Length = 614
Score = 48.8 bits (111), Expect = 1e-04
Identities = 23/35 (65%), Positives = 30/35 (85%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQK 388
R +KI+ ++GAGISTSAGIPDFRS + GL+ +LQK
Sbjct: 132 RHRKIVVIAGAGISTSAGIPDFRSTD-GLFKSLQK 165
>UniRef50_UPI000049979A Cluster: Sir2 family transcriptional
regulator; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
Sir2 family transcriptional regulator - Entamoeba
histolytica HM-1:IMSS
Length = 319
Score = 48.4 bits (110), Expect = 2e-04
Identities = 33/79 (41%), Positives = 49/79 (62%), Gaps = 2/79 (2%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTL 463
R K+++ L+GAGIS SAGIPDFRS G++ ++YE P+ A +E NF + P+ F+ +
Sbjct: 26 RSKRLVVLTGAGISVSAGIPDFRS-RNGMW---KRYE-PKVYASYE-NFVNK-PEMFWKM 78
Query: 464 AKEL--FPGSFKPTISHIS 514
EL KPT +H +
Sbjct: 79 CNELRNCTEGKKPTKAHFA 97
>UniRef50_Q2HG51 Cluster: Putative uncharacterized protein; n=2;
Pezizomycotina|Rep: Putative uncharacterized protein -
Chaetomium globosum (Soil fungus)
Length = 594
Score = 48.4 bits (110), Expect = 2e-04
Identities = 31/79 (39%), Positives = 49/79 (62%), Gaps = 6/79 (7%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQ-KYEL-PQPQAIFEINFFR--QNPKPFF 457
KKI+ ++GAGIS SAGIPDFRS TGL+ L+ +++L + +F+ + ++ + + F
Sbjct: 50 KKIVVIAGAGISVSAGIPDFRS-STGLFATLRGQHKLKASGKHLFDASVYKHDSSTESFH 108
Query: 458 TLAKEL--FPGSFKPTISH 508
T+ +EL KPT H
Sbjct: 109 TMVRELAQMTSDAKPTPFH 127
>UniRef50_Q5L014 Cluster: NAD-dependent deacetylase 1; n=7;
Bacillaceae|Rep: NAD-dependent deacetylase 1 -
Geobacillus kaustophilus
Length = 242
Score = 48.0 bits (109), Expect = 2e-04
Identities = 22/53 (41%), Positives = 32/53 (60%)
Frame = +2
Query: 260 IVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIF 418
I W+ + R + L+GAG+ST +G+PDFRSP TGL+ EL A++
Sbjct: 3 ITSWLAASR--HTVVLTGAGMSTESGLPDFRSPRTGLWARFNPSELATIDALY 53
>UniRef50_A6RSV6 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 1195
Score = 47.2 bits (107), Expect = 4e-04
Identities = 24/57 (42%), Positives = 38/57 (66%), Gaps = 1/57 (1%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQ-KYELPQPQAIFEINFFRQNPKP 451
+ +K++ ++GAGIST+ GIPDFRS E GLY +Q +Y+ +EIN + + +P
Sbjct: 23 KSRKVVVVTGAGISTNVGIPDFRS-EHGLYSMIQAQYDAALENPPWEINDYDIDDRP 78
Score = 36.3 bits (80), Expect = 0.72
Identities = 16/28 (57%), Positives = 20/28 (71%)
Frame = +1
Query: 511 FIRLLHEKGLLLRHYTQNIDTLERGAGI 594
FIR L + G L+R+YTQNID LE G+
Sbjct: 623 FIRSLRDNGRLVRNYTQNIDCLEEREGL 650
>UniRef50_Q73KE1 Cluster: NAD-dependent deacetylase; n=1; Treponema
denticola|Rep: NAD-dependent deacetylase - Treponema
denticola
Length = 251
Score = 47.2 bits (107), Expect = 4e-04
Identities = 27/77 (35%), Positives = 44/77 (57%), Gaps = 2/77 (2%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTL 463
+ + ++ +GAGIST AGI DFR + GL Y+ P + +F+I+ F ++P ++ +
Sbjct: 17 KARHLVAFTGAGISTLAGIKDFRGKD-GL------YKQPNTEKMFDIDVFYRDPSVYYGM 69
Query: 464 AKELFPG--SFKPTISH 508
AKE G +P I H
Sbjct: 70 AKEFIYGLEEKQPAIVH 86
>UniRef50_Q0UMU7 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 670
Score = 46.4 bits (105), Expect = 7e-04
Identities = 21/33 (63%), Positives = 29/33 (87%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQK 388
+KI+ ++GAGIS SAGIPDFRS TGL+++L+K
Sbjct: 125 RKIVVIAGAGISVSAGIPDFRS-ATGLFNSLKK 156
>UniRef50_Q8ZU41 Cluster: NAD-dependent deacetylase 1; n=3;
Pyrobaculum|Rep: NAD-dependent deacetylase 1 -
Pyrobaculum aerophilum
Length = 254
Score = 46.0 bits (104), Expect = 9e-04
Identities = 31/88 (35%), Positives = 48/88 (54%), Gaps = 2/88 (2%)
Frame = +2
Query: 299 ITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTL-AKEL 475
+ L+GAG+ST++GIPDFR P+ G++ + P+ FEI++F NP + L K L
Sbjct: 24 VALTGAGVSTASGIPDFRGPQ-GVWRRVD----PEK---FEISYFYNNPDEVWDLFVKYL 75
Query: 476 FPG-SFKPTISHIS*DFYMRKGSYYVII 556
P + KP +H + R G +I
Sbjct: 76 LPAFNVKPNPAHYALAEMERLGKLCAVI 103
>UniRef50_Q8F3Z6 Cluster: NAD-dependent deacetylase; n=4;
Leptospira|Rep: NAD-dependent deacetylase - Leptospira
interrogans
Length = 246
Score = 45.6 bits (103), Expect = 0.001
Identities = 26/56 (46%), Positives = 34/56 (60%)
Frame = +2
Query: 281 DRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPK 448
D+ +KI +SGAGIS +GIP FR E GL+ N + +L PQA F +NPK
Sbjct: 10 DKFQKISAISGAGISAESGIPTFRGSE-GLWKNFRAEDLATPQA------FSKNPK 58
>UniRef50_Q2GZ88 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 895
Score = 45.2 bits (102), Expect = 0.002
Identities = 22/49 (44%), Positives = 35/49 (71%), Gaps = 1/49 (2%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQ-KYELPQPQAIFEIN 427
+ +K++ ++GAGIST++GIPDFRS E GLY +Q +++ Q Q + N
Sbjct: 23 KSRKVVVITGAGISTNSGIPDFRS-ENGLYSLIQAQFDEAQQQQATDSN 70
>UniRef50_Q7S386 Cluster: Putative uncharacterized protein
NCU04859.1; n=1; Neurospora crassa|Rep: Putative
uncharacterized protein NCU04859.1 - Neurospora crassa
Length = 1327
Score = 44.8 bits (101), Expect = 0.002
Identities = 19/34 (55%), Positives = 28/34 (82%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQ 385
+ +K++ ++GAGIST++GIPDFRS E GLY +Q
Sbjct: 23 KARKVVVITGAGISTNSGIPDFRS-ENGLYSLIQ 55
>UniRef50_O07595 Cluster: NAD-dependent deacetylase; n=3;
Bacillus|Rep: NAD-dependent deacetylase - Bacillus
subtilis
Length = 247
Score = 44.8 bits (101), Expect = 0.002
Identities = 28/78 (35%), Positives = 47/78 (60%), Gaps = 4/78 (5%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAK 469
++I+ L+GAG+ST +GIPDFRS G++ + + +A+ +++F P+ F+ K
Sbjct: 12 QRIVVLTGAGMSTESGIPDFRS-AGGIWTE----DASRMEAM-SLDYFLSYPRLFWPKFK 65
Query: 470 ELF----PGSFKPTISHI 511
ELF GSF+P H+
Sbjct: 66 ELFQMKMSGSFEPNEGHL 83
>UniRef50_A3LRA1 Cluster: Transcriptional regulatory protein; n=2;
Saccharomycetales|Rep: Transcriptional regulatory
protein - Pichia stipitis (Yeast)
Length = 311
Score = 44.4 bits (100), Expect = 0.003
Identities = 19/44 (43%), Positives = 28/44 (63%)
Frame = +2
Query: 287 CKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIF 418
C+KI+ L GAG+S S+G+P FR + GL+ N +L P A +
Sbjct: 15 CRKIVALVGAGLSVSSGLPTFRGSQ-GLWKNFNMIDLATPDAFY 57
>UniRef50_Q81NT6 Cluster: NAD-dependent deacetylase; n=11; Bacillus
cereus group|Rep: NAD-dependent deacetylase - Bacillus
anthracis
Length = 242
Score = 44.4 bits (100), Expect = 0.003
Identities = 25/66 (37%), Positives = 37/66 (56%)
Frame = +2
Query: 281 DRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFT 460
++ KKI L+GAG ST +GIPDFRS GLY + + ++ ++PK F+
Sbjct: 12 EKAKKITVLTGAGASTESGIPDFRS-ANGLYAD------ANVEMYLSRGYYNRSPKEFWK 64
Query: 461 LAKELF 478
KE+F
Sbjct: 65 HYKEIF 70
>UniRef50_Q5KZE8 Cluster: NAD-dependent deacetylase 2; n=3;
Bacteria|Rep: NAD-dependent deacetylase 2 - Geobacillus
kaustophilus
Length = 247
Score = 44.4 bits (100), Expect = 0.003
Identities = 30/87 (34%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Frame = +2
Query: 260 IVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQ 439
+ +WIK I L+GAG+ST +GIPDFRS E GLY E ++++
Sbjct: 7 LAQWIKE--ANTIAVLTGAGMSTESGIPDFRS-ENGLYAQEDNVEY-----YLSEYYYKK 58
Query: 440 NPKPFFTLAKELFP----GSFKPTISH 508
+P F+ K +F G F P H
Sbjct: 59 DPVDFWRRFKRMFSLKMMGGFAPNDGH 85
>UniRef50_P53687 Cluster: NAD-dependent histone deacetylase HST3;
n=6; Saccharomycetales|Rep: NAD-dependent histone
deacetylase HST3 - Saccharomyces cerevisiae (Baker's
yeast)
Length = 447
Score = 44.4 bits (100), Expect = 0.003
Identities = 25/60 (41%), Positives = 39/60 (65%), Gaps = 5/60 (8%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQK-----YELPQPQAIFEINFFRQNPK 448
R ++I L+GAGIS +AGIPDFRS + GLY ++K + + + +F+I+ FR + K
Sbjct: 51 RSRRIACLTGAGISCNAGIPDFRSSD-GLYDLVKKDCSQYWSIKSGREMFDISLFRDDFK 109
>UniRef50_A1CTI6 Cluster: SIR2 family histone deacetylase, putative;
n=8; Eurotiomycetidae|Rep: SIR2 family histone
deacetylase, putative - Aspergillus clavatus
Length = 320
Score = 44.0 bits (99), Expect = 0.004
Identities = 22/47 (46%), Positives = 31/47 (65%)
Frame = +2
Query: 287 CKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEIN 427
CK+II L GAG+S S+G+P FR GL+ + + +L P+A FE N
Sbjct: 21 CKRIIALCGAGLSASSGLPTFRG-AGGLWRSYEAMDLATPEA-FEAN 65
>UniRef50_Q8CNF4 Cluster: NAD-dependent deacetylase; n=17;
Staphylococcus|Rep: NAD-dependent deacetylase -
Staphylococcus epidermidis (strain ATCC 12228)
Length = 246
Score = 44.0 bits (99), Expect = 0.004
Identities = 26/73 (35%), Positives = 38/73 (52%), Gaps = 1/73 (1%)
Frame = +2
Query: 293 KIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAKE 472
+I+ +GAG+S ++GIPDFRS GLY + K + P+ + I+ N + F E
Sbjct: 18 QIVFFTGAGVSVASGIPDFRS-MGGLYDEISK-DGQSPEYLLSIDHLHDNKESFINFYHE 75
Query: 473 -LFPGSFKPTISH 508
L KP I H
Sbjct: 76 RLLIADKKPNIVH 88
>UniRef50_UPI000023F1DF Cluster: hypothetical protein FG02466.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG02466.1 - Gibberella zeae PH-1
Length = 1569
Score = 43.6 bits (98), Expect = 0.005
Identities = 19/30 (63%), Positives = 26/30 (86%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLY 373
+ +K+I ++GAGIST++GIPDFRS E GLY
Sbjct: 640 KARKVIVVTGAGISTNSGIPDFRS-ENGLY 668
>UniRef50_Q1RPU9 Cluster: Zinc finger protein; n=1; Ciona
intestinalis|Rep: Zinc finger protein - Ciona
intestinalis (Transparent sea squirt)
Length = 320
Score = 43.6 bits (98), Expect = 0.005
Identities = 17/28 (60%), Positives = 23/28 (82%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLY 373
+K+ LSGAG+ST +GIPD+RS + GLY
Sbjct: 63 RKLFVLSGAGLSTESGIPDYRSKDVGLY 90
>UniRef50_Q8SSB6 Cluster: SIR2-LIKE PROTEIN INVOLVED IN TELOMERIC
SILENCING; n=1; Encephalitozoon cuniculi|Rep: SIR2-LIKE
PROTEIN INVOLVED IN TELOMERIC SILENCING -
Encephalitozoon cuniculi
Length = 425
Score = 43.6 bits (98), Expect = 0.005
Identities = 22/56 (39%), Positives = 41/56 (73%), Gaps = 8/56 (14%)
Frame = +2
Query: 245 SQPYGIV----RWIKSD----RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQK 388
S+P G++ WI+S+ ++++ ++GAGIS S+GIPDFRS ++GL+++++K
Sbjct: 63 SRPCGMIAVDSEWIRSNIKMFAKRRVVVITGAGISVSSGIPDFRS-KSGLFNDIKK 117
>UniRef50_Q6CAJ8 Cluster: Similar to sp|P53687 Saccharomyces
cerevisiae HST3 protein; n=1; Yarrowia lipolytica|Rep:
Similar to sp|P53687 Saccharomyces cerevisiae HST3
protein - Yarrowia lipolytica (Candida lipolytica)
Length = 385
Score = 43.6 bits (98), Expect = 0.005
Identities = 18/37 (48%), Positives = 27/37 (72%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYE 394
+CK+++ ++GAGIS SAGIPDFRS + + +K E
Sbjct: 23 KCKRVVCVTGAGISCSAGIPDFRSQQIAIGKGKKKDE 59
Score = 37.5 bits (83), Expect = 0.31
Identities = 18/40 (45%), Positives = 24/40 (60%)
Frame = +1
Query: 511 FIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHGIL 630
F+ L G LL YTQNID+LE + +K+V+ HG L
Sbjct: 113 FVAKLDTAGKLLSCYTQNIDSLEHKTEVSAKKIVQLHGHL 152
>UniRef50_UPI000023E2DA Cluster: hypothetical protein FG00460.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG00460.1 - Gibberella zeae PH-1
Length = 607
Score = 43.2 bits (97), Expect = 0.006
Identities = 28/79 (35%), Positives = 49/79 (62%), Gaps = 6/79 (7%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQ-KYELP-QPQAIFEINFFRQN--PKPFF 457
KKI+ ++GAGIS +AGIPDFRS TGL+ +++ ++ L + +F+ + ++ + + F
Sbjct: 131 KKIVVIAGAGISVAAGIPDFRS-STGLFASVKNQHNLKGSGKHLFDASVYKHDDTTESFH 189
Query: 458 TLAKELF--PGSFKPTISH 508
+ +E+ S KPT H
Sbjct: 190 AMVREMAAKTKSAKPTPFH 208
>UniRef50_A7B9E8 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 251
Score = 43.2 bits (97), Expect = 0.006
Identities = 23/73 (31%), Positives = 40/73 (54%)
Frame = +2
Query: 260 IVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQ 439
+ WI + + GAG+ST +GIPDFR G Y Q+ E+P + + I+FF +
Sbjct: 8 LAAWIAAS--PSTVFFGGAGVSTESGIPDFRG-ANGFY--FQEREIPL-ETVLSIDFFER 61
Query: 440 NPKPFFTLAKELF 478
+P+ ++ E++
Sbjct: 62 HPQAYWEWFHEIY 74
>UniRef50_A6R1B0 Cluster: Predicted protein; n=2; Onygenales|Rep:
Predicted protein - Ajellomyces capsulatus NAm1
Length = 547
Score = 43.2 bits (97), Expect = 0.006
Identities = 20/33 (60%), Positives = 26/33 (78%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQK 388
+KI+ ++GAGIS SAGIPDFRS GL+ L+K
Sbjct: 103 RKIVVIAGAGISVSAGIPDFRSAH-GLFKTLKK 134
>UniRef50_Q6CB00 Cluster: Similarities with tr|Q9UR39
Schizosaccharomyces pombe HST4P; n=1; Yarrowia
lipolytica|Rep: Similarities with tr|Q9UR39
Schizosaccharomyces pombe HST4P - Yarrowia lipolytica
(Candida lipolytica)
Length = 721
Score = 42.7 bits (96), Expect = 0.008
Identities = 22/52 (42%), Positives = 38/52 (73%), Gaps = 2/52 (3%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQ-KYELPQP-QAIFEINFFRQ 439
++++ ++GAGIS AGIPDFRS + GL+ +L+ +Y L +A+F+ + FR+
Sbjct: 176 QRLVVITGAGISVHAGIPDFRS-DKGLFVSLKDEYNLKTTGKALFDASVFRE 226
>UniRef50_A5DW75 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 379
Score = 42.7 bits (96), Expect = 0.008
Identities = 19/45 (42%), Positives = 28/45 (62%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIF 418
+CKKI+ L GAG+ S+G+P FR + GL+ N +L P A +
Sbjct: 14 KCKKIVALVGAGLLASSGLPVFRGSQ-GLWKNYNMIDLATPDAFY 57
>UniRef50_Q9Y6E7 Cluster: NAD-dependent deacetylase sirtuin-4; n=23;
Deuterostomia|Rep: NAD-dependent deacetylase sirtuin-4 -
Homo sapiens (Human)
Length = 314
Score = 42.7 bits (96), Expect = 0.008
Identities = 16/28 (57%), Positives = 24/28 (85%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLY 373
K+++ ++GAGIST +GIPD+RS + GLY
Sbjct: 55 KRLLVMTGAGISTESGIPDYRSEKVGLY 82
>UniRef50_Q9UR39 Cluster: NAD-dependent deacetylase hst4; n=1;
Schizosaccharomyces pombe|Rep: NAD-dependent deacetylase
hst4 - Schizosaccharomyces pombe (Fission yeast)
Length = 415
Score = 42.7 bits (96), Expect = 0.008
Identities = 21/39 (53%), Positives = 31/39 (79%), Gaps = 1/39 (2%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQ-KYEL 397
+ K+I+ ++GAGIS AGIPDFRS E GL+ +L+ +Y+L
Sbjct: 56 KAKRIVVVTGAGISCDAGIPDFRSSE-GLFSSLRAEYKL 93
>UniRef50_Q03ZB1 Cluster: NAD-dependent protein deacetylase, SIR2
family; n=3; Leuconostocaceae|Rep: NAD-dependent protein
deacetylase, SIR2 family - Leuconostoc mesenteroides
subsp. mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 234
Score = 42.3 bits (95), Expect = 0.011
Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 2/93 (2%)
Frame = +2
Query: 281 DRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNP-KPF- 454
D K I+ ++GAG+ST +GIPD+RS + G+Y + QP+ + F P K +
Sbjct: 12 DNAKNIVFMTGAGVSTLSGIPDYRS-KGGIYDGISL----QPEYLLSATAFHNEPEKQYQ 66
Query: 455 FTLAKELFPGSFKPTISHIS*DFYMRKGSYYVI 553
F + FP + P + H R+G +I
Sbjct: 67 FMIDNMYFPEAV-PNVIHKKMAALTRQGKAKII 98
>UniRef50_A5WD15 Cluster: Silent information regulator protein Sir2;
n=2; Psychrobacter|Rep: Silent information regulator
protein Sir2 - Psychrobacter sp. PRwf-1
Length = 249
Score = 42.3 bits (95), Expect = 0.011
Identities = 21/55 (38%), Positives = 33/55 (60%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPK 448
+ +I L+GAGIS +GIP FR +TGL+ N + +L IN F+++P+
Sbjct: 14 KANRIFLLTGAGISAESGIPTFRDKQTGLWENYRAEDLA------NINAFKKDPQ 62
>UniRef50_A5AF92 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 343
Score = 42.3 bits (95), Expect = 0.011
Identities = 32/86 (37%), Positives = 43/86 (50%), Gaps = 1/86 (1%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTL 463
+ K ++ +GAGISTS GIPDFR P+ G++ LQ+ PQA + F R P
Sbjct: 74 KSKHLVVFTGAGISTSCGIPDFRGPK-GIW-TLQREGKALPQA--SLPFHRAMPSMTHMA 129
Query: 464 AKEL-FPGSFKPTISHIS*DFYMRKG 538
EL G K IS ++R G
Sbjct: 130 LVELEKAGILKFVISQNIDGLHLRSG 155
Score = 33.9 bits (74), Expect = 3.9
Identities = 16/34 (47%), Positives = 21/34 (61%)
Frame = +1
Query: 523 LHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
L + G+L +QNID L +GIP +KL E HG
Sbjct: 133 LEKAGILKFVISQNIDGLHLRSGIPRDKLAELHG 166
>UniRef50_A0LG97 Cluster: Silent information regulator protein Sir2;
n=1; Syntrophobacter fumaroxidans MPOB|Rep: Silent
information regulator protein Sir2 - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 248
Score = 41.9 bits (94), Expect = 0.015
Identities = 26/64 (40%), Positives = 36/64 (56%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTL 463
R + + L+GAGIS +GIPDFRS + GL+ KY+ P I FR NP +T+
Sbjct: 13 RSRYTVVLTGAGISVESGIPDFRSKD-GLW---SKYD---PAEYGYIGSFRANPAKVWTM 65
Query: 464 AKEL 475
E+
Sbjct: 66 LTEM 69
>UniRef50_Q974M6 Cluster: NAD-dependent deacetylase; n=8;
Thermoprotei|Rep: NAD-dependent deacetylase - Sulfolobus
tokodaii
Length = 250
Score = 41.9 bits (94), Expect = 0.015
Identities = 26/64 (40%), Positives = 39/64 (60%)
Frame = +2
Query: 299 ITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAKELF 478
I +GAGIST++GIPDFR P GL+ +KY P+ + I +F+++PK F+ +
Sbjct: 17 IAFTGAGISTASGIPDFRGP-NGLW---KKYS-PE---LATIEYFKKDPKGFWEFYRLRM 68
Query: 479 PGSF 490
G F
Sbjct: 69 RGLF 72
>UniRef50_UPI00006CB0CC Cluster: transcriptional regulator, Sir2
family protein; n=1; Tetrahymena thermophila SB210|Rep:
transcriptional regulator, Sir2 family protein -
Tetrahymena thermophila SB210
Length = 442
Score = 41.5 bits (93), Expect = 0.019
Identities = 27/77 (35%), Positives = 39/77 (50%), Gaps = 1/77 (1%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRS-PETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFT 460
+ K + L+GAG+ST++GIPD+RS T L K+EL + + F + KP
Sbjct: 67 KSKNAVILTGAGVSTASGIPDYRSGANTILKTGPGKWELEENKK----KFLEEKGKPQII 122
Query: 461 LAKELFPGSFKPTISHI 511
LA FP IS +
Sbjct: 123 LAINAFPSPTHMAISKL 139
>UniRef50_UPI000049971A Cluster: Sir2 family transcriptional
regulator; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
Sir2 family transcriptional regulator - Entamoeba
histolytica HM-1:IMSS
Length = 285
Score = 41.5 bits (93), Expect = 0.019
Identities = 24/76 (31%), Positives = 43/76 (56%)
Frame = +2
Query: 281 DRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFT 460
++ K + L+GAGIS +GIPDFRS GL+ ++Y+ P + F+++P+ F+
Sbjct: 33 EKSKNVTVLTGAGISVESGIPDFRS-SNGLW---KRYD---PSVYGSYSNFKKHPELFWK 85
Query: 461 LAKELFPGSFKPTISH 508
+ +E+ + P H
Sbjct: 86 MTEEIHKITAYPNHVH 101
>UniRef50_A5UYK2 Cluster: Silent information regulator protein Sir2;
n=2; Roseiflexus|Rep: Silent information regulator
protein Sir2 - Roseiflexus sp. RS-1
Length = 261
Score = 41.5 bits (93), Expect = 0.019
Identities = 20/58 (34%), Positives = 31/58 (53%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFF 457
R + ++GAGIST +GIPDFR P+ H P + ++ F +NP+ F+
Sbjct: 20 RAHSAVAITGAGISTPSGIPDFRGPDGAWKH-------VDPSEVASLHNFLRNPRAFY 70
>UniRef50_A4RMS1 Cluster: Putative uncharacterized protein; n=2;
Sordariomycetes|Rep: Putative uncharacterized protein -
Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 666
Score = 41.5 bits (93), Expect = 0.019
Identities = 19/34 (55%), Positives = 28/34 (82%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQKY 391
K+I+ ++GAGIS SAGIPDFRS ++GL+ + K+
Sbjct: 140 KRIVIIAGAGISVSAGIPDFRS-QSGLFKSNGKH 172
>UniRef50_Q8R216 Cluster: NAD-dependent deacetylase sirtuin-4; n=7;
cellular organisms|Rep: NAD-dependent deacetylase
sirtuin-4 - Mus musculus (Mouse)
Length = 333
Score = 41.5 bits (93), Expect = 0.019
Identities = 16/28 (57%), Positives = 23/28 (82%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLY 373
KK++ ++GAGIST + IPD+RS + GLY
Sbjct: 52 KKLLVMTGAGISTESSIPDYRSEKVGLY 79
>UniRef50_Q95Q89 Cluster: Yeast sir related protein 2.4; n=2;
Caenorhabditis|Rep: Yeast sir related protein 2.4 -
Caenorhabditis elegans
Length = 299
Score = 41.1 bits (92), Expect = 0.025
Identities = 19/41 (46%), Positives = 25/41 (60%)
Frame = +1
Query: 514 IRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHGILHI 636
I LH+ G + TQN+D L+R GIP E L+E HG L +
Sbjct: 108 ILALHKAGYIKTIITQNVDGLDRKVGIPVEDLIEVHGNLFL 148
>UniRef50_Q6BVM7 Cluster: Similar to CA4170|IPF7784 Candida
albicans; n=2; Saccharomycetaceae|Rep: Similar to
CA4170|IPF7784 Candida albicans - Debaryomyces hansenii
(Yeast) (Torulaspora hansenii)
Length = 301
Score = 41.1 bits (92), Expect = 0.025
Identities = 18/45 (40%), Positives = 28/45 (62%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIF 418
+ K+I+ L GAG+S S+G+P FR + GL+ N +L P A +
Sbjct: 14 KSKRIVALVGAGLSVSSGLPTFRGSQ-GLWKNFNMIDLATPDAFY 57
>UniRef50_Q2KH01 Cluster: Putative uncharacterized protein; n=2;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea 70-15
Length = 449
Score = 41.1 bits (92), Expect = 0.025
Identities = 22/62 (35%), Positives = 29/62 (46%)
Frame = +1
Query: 505 TYFIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHGILHITLSGIAARNTHWSLSK 684
T F LL E+ ++ H TQNID LER E K V HG L + + W +
Sbjct: 156 TPFHVLLEEQPSIVLHITQNIDCLERSLPAAERKTVRLHGCLDTVRCSVCPSDHRWLRTD 215
Query: 685 KG 690
+G
Sbjct: 216 EG 217
>UniRef50_A1ZHW6 Cluster: NAD-dependent deacetylase; n=2;
Microscilla marina ATCC 23134|Rep: NAD-dependent
deacetylase - Microscilla marina ATCC 23134
Length = 279
Score = 40.7 bits (91), Expect = 0.034
Identities = 22/52 (42%), Positives = 30/52 (57%)
Frame = +2
Query: 293 KIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPK 448
K++ L+GAGIS +GIP FR E Y + QPQ I + F+QNP+
Sbjct: 20 KMVVLTGAGISAESGIPTFRGKEG--YWKIGSVNY-QPQEIGTMKMFKQNPQ 68
>UniRef50_Q9FE17 Cluster: Sir2-like protein; n=9; Magnoliophyta|Rep:
Sir2-like protein - Arabidopsis thaliana (Mouse-ear
cress)
Length = 473
Score = 40.7 bits (91), Expect = 0.034
Identities = 31/86 (36%), Positives = 43/86 (50%), Gaps = 1/86 (1%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTL 463
+ K ++ +GAGISTS GIPDFR P+ G++ LQ+ P+A + F R P
Sbjct: 43 KSKHLVVFTGAGISTSCGIPDFRGPK-GIW-TLQREGKDLPKA--SLPFHRAMPSMTHMA 98
Query: 464 AKEL-FPGSFKPTISHIS*DFYMRKG 538
EL G K IS ++R G
Sbjct: 99 LVELERAGILKFVISQNVDGLHLRSG 124
Score = 33.5 bits (73), Expect = 5.1
Identities = 16/34 (47%), Positives = 20/34 (58%)
Frame = +1
Query: 523 LHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
L G+L +QN+D L +GIP EKL E HG
Sbjct: 102 LERAGILKFVISQNVDGLHLRSGIPREKLSELHG 135
>UniRef50_Q7SB01 Cluster: Putative uncharacterized protein
NCU07624.1; n=1; Neurospora crassa|Rep: Putative
uncharacterized protein NCU07624.1 - Neurospora crassa
Length = 437
Score = 40.7 bits (91), Expect = 0.034
Identities = 16/26 (61%), Positives = 20/26 (76%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPE 361
+ K + +GAG+STSAGIPDFR PE
Sbjct: 33 KSKHFVVFTGAGVSTSAGIPDFRGPE 58
>UniRef50_Q8REC3 Cluster: NAD-dependent deacetylase; n=3;
Fusobacterium nucleatum|Rep: NAD-dependent deacetylase -
Fusobacterium nucleatum subsp. nucleatum
Length = 252
Score = 40.7 bits (91), Expect = 0.034
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFT-LA 466
K ++ GAG ST +G+ DFR + GLY L K + +P+ + +FF + F +
Sbjct: 20 KYLVFFGGAGTSTDSGVKDFRGKD-GLYKTLYK-DKYRPEEVLSSDFFYSHRDIFMKYVE 77
Query: 467 KELFPGSFKPTISHIS 514
KEL KP H++
Sbjct: 78 KELNIKGLKPNKGHMA 93
>UniRef50_A0NQ49 Cluster: Silent information regulator protein Sir2;
n=1; Stappia aggregata IAM 12614|Rep: Silent information
regulator protein Sir2 - Stappia aggregata IAM 12614
Length = 260
Score = 40.3 bits (90), Expect = 0.044
Identities = 16/23 (69%), Positives = 21/23 (91%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSP 358
++I+ L+GAGIST +GIPDFRSP
Sbjct: 23 RQIVALTGAGISTESGIPDFRSP 45
Score = 34.7 bits (76), Expect = 2.2
Identities = 16/39 (41%), Positives = 23/39 (58%)
Frame = +1
Query: 508 YFIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
+ + L G L+ TQN+D L + AG P++ LVE HG
Sbjct: 98 FALTTLARSGKLVCLITQNVDGLHQRAGFPDDLLVEIHG 136
>UniRef50_Q7PS76 Cluster: ENSANGP00000025231; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000025231 - Anopheles gambiae
str. PEST
Length = 182
Score = 40.3 bits (90), Expect = 0.044
Identities = 17/26 (65%), Positives = 21/26 (80%)
Frame = +2
Query: 296 IITLSGAGISTSAGIPDFRSPETGLY 373
I+ L+GAGIST +GIPD+RS GLY
Sbjct: 1 ILVLTGAGISTESGIPDYRSEGVGLY 26
>UniRef50_A2DKF0 Cluster: Transcriptional regulator, Sir2 family
protein; n=1; Trichomonas vaginalis G3|Rep:
Transcriptional regulator, Sir2 family protein -
Trichomonas vaginalis G3
Length = 347
Score = 40.3 bits (90), Expect = 0.044
Identities = 21/39 (53%), Positives = 24/39 (61%)
Frame = +1
Query: 508 YFIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
YFI L G L R Y+QN+DTLE G+PE KL HG
Sbjct: 140 YFIAELENHGKLQRLYSQNVDTLE--CGVPESKLRCVHG 176
>UniRef50_Q6C8C7 Cluster: Similar to DEHA0C01507g Debaryomyces
hansenii IPF 2468.1; n=2; Ascomycota|Rep: Similar to
DEHA0C01507g Debaryomyces hansenii IPF 2468.1 - Yarrowia
lipolytica (Candida lipolytica)
Length = 303
Score = 40.3 bits (90), Expect = 0.044
Identities = 19/41 (46%), Positives = 27/41 (65%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQA 412
+KI+ L GAG+S S+G+P FR E G++ N EL P+A
Sbjct: 17 RKILALVGAGLSQSSGLPTFRG-EGGIWRNYDAAELATPEA 56
>UniRef50_A2QWZ2 Cluster: Function: human SIRT5 belongs to the
Sir2-like proteins precursor; n=1; Aspergillus
niger|Rep: Function: human SIRT5 belongs to the
Sir2-like proteins precursor - Aspergillus niger
Length = 258
Score = 40.3 bits (90), Expect = 0.044
Identities = 20/47 (42%), Positives = 30/47 (63%)
Frame = +2
Query: 287 CKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEIN 427
C+++I L GAGIS S+G+P FR GL+ + +L P+A F+ N
Sbjct: 21 CRRVIALLGAGISASSGLPTFRG-AGGLWRSYDATDLATPEA-FDAN 65
>UniRef50_Q1MT39 Cluster: Novel protein similar to vertebratesirtuin
(Silent mating type information regulation 2 homolog) 7;
n=2; Danio rerio|Rep: Novel protein similar to
vertebratesirtuin (Silent mating type information
regulation 2 homolog) 7 - Danio rerio (Zebrafish)
(Brachydanio rerio)
Length = 376
Score = 39.9 bits (89), Expect = 0.059
Identities = 18/35 (51%), Positives = 25/35 (71%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQK 388
R K ++ +GAGIST+A IPD+R P G++ LQK
Sbjct: 95 RAKHLVIYTGAGISTAASIPDYRGP-NGVWTQLQK 128
>UniRef50_Q3E2I1 Cluster: Silent information regulator protein Sir2;
n=7; Bacteria|Rep: Silent information regulator protein
Sir2 - Chloroflexus aurantiacus J-10-fl
Length = 254
Score = 39.9 bits (89), Expect = 0.059
Identities = 16/39 (41%), Positives = 24/39 (61%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQP 406
+ + L+GAG+S +GIP FR +TGL+ + EL P
Sbjct: 19 RHVTVLTGAGVSAESGIPTFRDAQTGLWSHFDPEELASP 57
>UniRef50_Q2YZT2 Cluster: Putative uncharacterized protein; n=1;
uncultured delta proteobacterium|Rep: Putative
uncharacterized protein - uncultured delta
proteobacterium
Length = 254
Score = 39.9 bits (89), Expect = 0.059
Identities = 18/37 (48%), Positives = 25/37 (67%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYE 394
+ K +I ++GAGIS +GIPDFRSP GL+ +E
Sbjct: 14 KSKYVIAMTGAGISVESGIPDFRSP-GGLWSRFDPFE 49
>UniRef50_Q8IRR5 Cluster: CG3187-PC, isoform C; n=4; Diptera|Rep:
CG3187-PC, isoform C - Drosophila melanogaster (Fruit
fly)
Length = 312
Score = 39.9 bits (89), Expect = 0.059
Identities = 16/26 (61%), Positives = 21/26 (80%)
Frame = +2
Query: 296 IITLSGAGISTSAGIPDFRSPETGLY 373
++ L+GAGIST +GIPD+RS GLY
Sbjct: 48 VLVLTGAGISTESGIPDYRSEGVGLY 73
>UniRef50_Q7R0R8 Cluster: GLP_79_6121_4343; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_79_6121_4343 - Giardia lamblia ATCC
50803
Length = 592
Score = 39.9 bits (89), Expect = 0.059
Identities = 20/42 (47%), Positives = 27/42 (64%), Gaps = 1/42 (2%)
Frame = +1
Query: 508 YFIRLLHEKGLLLRHYTQNIDTLERGAGIPE-EKLVEAHGIL 630
YF+R L ++G+L TQNID LERG G+ E + + HG L
Sbjct: 168 YFLRFLADEGILKLILTQNIDELERGVGLSEVVDVKQVHGSL 209
>UniRef50_Q12Y78 Cluster: Silent information regulator protein Sir2;
n=1; Methanococcoides burtonii DSM 6242|Rep: Silent
information regulator protein Sir2 - Methanococcoides
burtonii (strain DSM 6242)
Length = 245
Score = 39.9 bits (89), Expect = 0.059
Identities = 22/57 (38%), Positives = 36/57 (63%)
Frame = +2
Query: 299 ITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAK 469
+ L+GAG+ST +GIPDFR +G+Y+ K++ IF I+ F ++P F+ +K
Sbjct: 15 VVLTGAGVSTFSGIPDFRG-RSGVYN---KFD---ADLIFSIDHFNKDPAYFYAHSK 64
>UniRef50_UPI0000519F58 Cluster: PREDICTED: similar to Sirt4
CG3187-PC, isoform C isoform 2; n=2; Endopterygota|Rep:
PREDICTED: similar to Sirt4 CG3187-PC, isoform C isoform
2 - Apis mellifera
Length = 302
Score = 39.5 bits (88), Expect = 0.078
Identities = 18/31 (58%), Positives = 21/31 (67%)
Frame = +2
Query: 281 DRCKKIITLSGAGISTSAGIPDFRSPETGLY 373
D I L+GAGIST +GIPD+RS GLY
Sbjct: 38 DSHDNICVLTGAGISTESGIPDYRSEGVGLY 68
>UniRef50_Q9VH08 Cluster: CG6284-PA; n=9; Eumetazoa|Rep: CG6284-PA -
Drosophila melanogaster (Fruit fly)
Length = 317
Score = 39.5 bits (88), Expect = 0.078
Identities = 20/42 (47%), Positives = 28/42 (66%)
Frame = +2
Query: 296 IITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFE 421
++ +GAGISTSAGIPDFR P+ G++ +K E P F+
Sbjct: 47 VVLHTGAGISTSAGIPDFRGPK-GVWTLEEKGEKPDFNVSFD 87
>UniRef50_A7AWG1 Cluster: Transcriptional regulator, Sir2 family
domain containing protein; n=2; Babesia bovis|Rep:
Transcriptional regulator, Sir2 family domain containing
protein - Babesia bovis
Length = 656
Score = 39.5 bits (88), Expect = 0.078
Identities = 16/25 (64%), Positives = 20/25 (80%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSP 358
R K ++ SGAG+ST+AGIPDFR P
Sbjct: 46 RAKNVVLHSGAGMSTAAGIPDFRGP 70
>UniRef50_Q88BY5 Cluster: NAD-dependent deacetylase; n=9;
Bacteria|Rep: NAD-dependent deacetylase - Pseudomonas
putida (strain KT2440)
Length = 262
Score = 39.5 bits (88), Expect = 0.078
Identities = 27/79 (34%), Positives = 41/79 (51%), Gaps = 2/79 (2%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFT- 460
R K ++ +GAGIS +GIP FR TGL+ K++ PQ + + FR NP ++
Sbjct: 13 RSKTVVFFTGAGISADSGIPTFRDKLTGLW---AKHD---PQRLETADAFRANPTLVWSW 66
Query: 461 -LAKELFPGSFKPTISHIS 514
L + KP +H+S
Sbjct: 67 YLWRRHQVSQAKPNSAHLS 85
>UniRef50_P53688 Cluster: NAD-dependent histone deacetylase HST4;
n=5; Saccharomycetales|Rep: NAD-dependent histone
deacetylase HST4 - Saccharomyces cerevisiae (Baker's
yeast)
Length = 370
Score = 39.1 bits (87), Expect = 0.10
Identities = 16/24 (66%), Positives = 21/24 (87%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPE 361
K+++ +SGAGIS +AGIPDFRS E
Sbjct: 93 KRMVVVSGAGISVAAGIPDFRSSE 116
>UniRef50_UPI00015B4FA0 Cluster: PREDICTED: similar to chromatin
regulatory protein sir2; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to chromatin regulatory protein sir2
- Nasonia vitripennis
Length = 736
Score = 38.7 bits (86), Expect = 0.14
Identities = 16/27 (59%), Positives = 21/27 (77%)
Frame = +2
Query: 293 KIITLSGAGISTSAGIPDFRSPETGLY 373
KI ++GAGIST +GIPD+RS GL+
Sbjct: 476 KICVITGAGISTESGIPDYRSEGVGLF 502
>UniRef50_Q5KG84 Cluster: Hst4 protein, putative; n=2;
Filobasidiella neoformans|Rep: Hst4 protein, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 478
Score = 38.7 bits (86), Expect = 0.14
Identities = 18/33 (54%), Positives = 24/33 (72%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQK 388
K+I+ +SGAG+ST A IPDFRS +GL+ K
Sbjct: 44 KRIVVVSGAGVSTGAAIPDFRS-ASGLFSGKTK 75
>UniRef50_Q9RYD4 Cluster: NAD-dependent deacetylase; n=4;
Deinococci|Rep: NAD-dependent deacetylase - Deinococcus
radiodurans
Length = 246
Score = 38.7 bits (86), Expect = 0.14
Identities = 16/41 (39%), Positives = 25/41 (60%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQA 412
+++ L+GAGIS +GIP FR +TG + + +L P A
Sbjct: 14 RRVAVLTGAGISAESGIPTFRDAQTGHWARFRPEDLASPDA 54
>UniRef50_A5USR3 Cluster: Silent information regulator protein Sir2;
n=3; Chloroflexi (class)|Rep: Silent information
regulator protein Sir2 - Roseiflexus sp. RS-1
Length = 259
Score = 38.3 bits (85), Expect = 0.18
Identities = 15/41 (36%), Positives = 24/41 (58%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQA 412
++++ L+G G++ +GIP FR TG + EL PQA
Sbjct: 17 RRVVALTGGGVAAESGIPSFREAHTGHWAQYDVSELATPQA 57
>UniRef50_A3ZMQ7 Cluster: Sir2 family, possible ADP
ribosyltransferase; n=1; Blastopirellula marina DSM
3645|Rep: Sir2 family, possible ADP ribosyltransferase -
Blastopirellula marina DSM 3645
Length = 252
Score = 38.3 bits (85), Expect = 0.18
Identities = 17/33 (51%), Positives = 21/33 (63%)
Frame = +2
Query: 260 IVRWIKSDRCKKIITLSGAGISTSAGIPDFRSP 358
+ RW+ + T GAGIST +GIPDFRSP
Sbjct: 10 VARWLAESESTVLFT--GAGISTESGIPDFRSP 40
>UniRef50_Q7JMD3 Cluster: Putative uncharacterized protein sir-2.2;
n=4; Caenorhabditis|Rep: Putative uncharacterized
protein sir-2.2 - Caenorhabditis elegans
Length = 289
Score = 38.3 bits (85), Expect = 0.18
Identities = 17/29 (58%), Positives = 23/29 (79%), Gaps = 2/29 (6%)
Frame = +2
Query: 293 KIITLSGAGISTSA--GIPDFRSPETGLY 373
K++ +SGAGIST + GIPD+RS + GLY
Sbjct: 29 KLLVISGAGISTESVPGIPDYRSKDVGLY 57
>UniRef50_Q6CQA7 Cluster: Kluyveromyces lactis strain NRRL Y-1140
chromosome D of strain NRRL Y- 1140 of Kluyveromyces
lactis; n=1; Kluyveromyces lactis|Rep: Kluyveromyces
lactis strain NRRL Y-1140 chromosome D of strain NRRL Y-
1140 of Kluyveromyces lactis - Kluyveromyces lactis
(Yeast) (Candida sphaerica)
Length = 399
Score = 38.3 bits (85), Expect = 0.18
Identities = 17/32 (53%), Positives = 24/32 (75%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQ 385
K+I+ + GAG+S +AGIPDFRS GL+ L+
Sbjct: 113 KRIVVVQGAGVSVAAGIPDFRS-ANGLFTTLK 143
>UniRef50_Q9CBW6 Cluster: NAD-dependent deacetylase; n=14;
Mycobacterium|Rep: NAD-dependent deacetylase -
Mycobacterium leprae
Length = 237
Score = 38.3 bits (85), Expect = 0.18
Identities = 15/39 (38%), Positives = 23/39 (58%)
Frame = +2
Query: 293 KIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQ 409
+++ LSGAGIS + +P FR + GL+ Y+L Q
Sbjct: 2 RVVVLSGAGISAESDVPTFRDDKNGLWARFDPYQLSSTQ 40
>UniRef50_Q88ZA0 Cluster: NAD-dependent deacetylase; n=4;
Lactobacillus|Rep: NAD-dependent deacetylase -
Lactobacillus plantarum
Length = 234
Score = 38.3 bits (85), Expect = 0.18
Identities = 25/78 (32%), Positives = 42/78 (53%), Gaps = 3/78 (3%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLY--HNLQKYELPQPQAIFEINFFRQNPKPFF 457
+ + I+ ++GAG+ST +GIPD+RS + GLY H+ +Y L F ++P F+
Sbjct: 13 QAQHIVFMTGAGVSTPSGIPDYRS-KNGLYTEHHNAEYYLSHA-------FLAEHPLEFY 64
Query: 458 T-LAKELFPGSFKPTISH 508
L L+ +P + H
Sbjct: 65 QYLQSNLYYPDAQPNVIH 82
>UniRef50_Q89LY4 Cluster: NAD-dependent deacetylase 1; n=12;
Proteobacteria|Rep: NAD-dependent deacetylase 1 -
Bradyrhizobium japonicum
Length = 254
Score = 38.3 bits (85), Expect = 0.18
Identities = 16/23 (69%), Positives = 18/23 (78%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSP 358
K I+ +GAGIST GIPDFRSP
Sbjct: 23 KTIVPFTGAGISTECGIPDFRSP 45
>UniRef50_A1ZPG8 Cluster: NAD-dependent deacetylase; n=1;
Microscilla marina ATCC 23134|Rep: NAD-dependent
deacetylase - Microscilla marina ATCC 23134
Length = 278
Score = 37.9 bits (84), Expect = 0.24
Identities = 22/77 (28%), Positives = 40/77 (51%), Gaps = 3/77 (3%)
Frame = +2
Query: 293 KIIT-LSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPF--FTL 463
K+IT L+GAGIS +G+P +R + + Y +P+ + FF++NP F L
Sbjct: 20 KLITFLTGAGISAESGVPTYRGTDGIWVEGSRNY---KPEEFATLRFFKENPAEVWKFVL 76
Query: 464 AKELFPGSFKPTISHIS 514
+++ +P H++
Sbjct: 77 YRKVSFRDLQPNAGHLA 93
>UniRef50_Q2LSF2 Cluster: Sir2 family of NAD+-dependent deacetylase;
n=2; Syntrophus aciditrophicus SB|Rep: Sir2 family of
NAD+-dependent deacetylase - Syntrophus aciditrophicus
(strain SB)
Length = 271
Score = 37.5 bits (83), Expect = 0.31
Identities = 13/22 (59%), Positives = 19/22 (86%)
Frame = +2
Query: 293 KIITLSGAGISTSAGIPDFRSP 358
+++ +GAG+ST +GIPDFRSP
Sbjct: 27 RVVVFTGAGVSTESGIPDFRSP 48
>UniRef50_Q046W9 Cluster: NAD-dependent protein deacetylase, SIR2
family; n=6; Lactobacillus|Rep: NAD-dependent protein
deacetylase, SIR2 family - Lactobacillus gasseri (strain
ATCC 33323 / DSM 20243)
Length = 237
Score = 37.5 bits (83), Expect = 0.31
Identities = 25/69 (36%), Positives = 39/69 (56%), Gaps = 1/69 (1%)
Frame = +2
Query: 305 LSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPK-PFFTLAKELFP 481
L+GAG+ST + IPD+RS + G+Y+ + E P+ Q + E F + K F + FP
Sbjct: 23 LTGAGVSTPSHIPDYRS-KNGIYNGIS--ESPE-QILSEDTLFHEPAKFHHFVMENMYFP 78
Query: 482 GSFKPTISH 508
+ +P I H
Sbjct: 79 NA-QPNIIH 86
>UniRef50_A1FG80 Cluster: Silent information regulator protein Sir2;
n=3; Pseudomonas|Rep: Silent information regulator
protein Sir2 - Pseudomonas putida W619
Length = 252
Score = 37.5 bits (83), Expect = 0.31
Identities = 20/50 (40%), Positives = 27/50 (54%)
Frame = +2
Query: 296 IITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNP 445
I+ +GAG+S +GIP FR TGL +E PQ + FR+NP
Sbjct: 17 IMVFTGAGVSAGSGIPTFRDELTGL------WERQDPQRLETAQAFRENP 60
>UniRef50_Q8IKW2 Cluster: Putative uncharacterized protein; n=1;
Plasmodium falciparum 3D7|Rep: Putative uncharacterized
protein - Plasmodium falciparum (isolate 3D7)
Length = 1304
Score = 37.5 bits (83), Expect = 0.31
Identities = 19/34 (55%), Positives = 24/34 (70%)
Frame = +2
Query: 296 IITLSGAGISTSAGIPDFRSPETGLYHNLQKYEL 397
I+ SGAGISTS+G+ DFR P TG++ N EL
Sbjct: 48 IVVHSGAGISTSSGLQDFRGP-TGIWTNEHLNEL 80
>UniRef50_Q1EP52 Cluster: Transcriptional regulator Sir2 family
protein; n=1; Musa balbisiana|Rep: Transcriptional
regulator Sir2 family protein - Musa balbisiana (Banana)
Length = 217
Score = 37.1 bits (82), Expect = 0.41
Identities = 14/24 (58%), Positives = 20/24 (83%)
Frame = +2
Query: 281 DRCKKIITLSGAGISTSAGIPDFR 352
D +K++ L+GAGIST +GIPD+R
Sbjct: 181 DTSRKLVVLTGAGISTESGIPDYR 204
>UniRef50_Q7RP35 Cluster: Sir2-like protein; n=5; Plasmodium
(Vinckeia)|Rep: Sir2-like protein - Plasmodium yoelii
yoelii
Length = 1159
Score = 37.1 bits (82), Expect = 0.41
Identities = 19/34 (55%), Positives = 22/34 (64%), Gaps = 3/34 (8%)
Frame = +2
Query: 296 IITLSGAGISTSAGIPDFRSPE---TGLYHNLQK 388
I+ SGAGISTS+G+ DFR P T YHN K
Sbjct: 48 IVVHSGAGISTSSGLQDFRGPTGIWTNEYHNNNK 81
>UniRef50_A7DQD6 Cluster: Silent information regulator protein Sir2;
n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
Silent information regulator protein Sir2 - Candidatus
Nitrosopumilus maritimus SCM1
Length = 242
Score = 37.1 bits (82), Expect = 0.41
Identities = 18/44 (40%), Positives = 27/44 (61%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFE 421
KKI+ ++GAGIS +GIP FR + GL+ N +L A ++
Sbjct: 15 KKIVFVTGAGISQESGIPTFRGKD-GLWRNYDAMKLATIDAFYD 57
>UniRef50_Q67KQ0 Cluster: NAD-dependent deacetylase; n=1;
Symbiobacterium thermophilum|Rep: NAD-dependent
deacetylase - Symbiobacterium thermophilum
Length = 251
Score = 37.1 bits (82), Expect = 0.41
Identities = 20/60 (33%), Positives = 33/60 (55%)
Frame = +2
Query: 299 ITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAKELF 478
+ L+GAG ST +G+PDFRS TGL+ ++ P ++ + R+ P F+ + F
Sbjct: 19 VALTGAGASTESGLPDFRS-NTGLWKDV------DPVSLISMTALRRRPVDFYRFYRMRF 71
Score = 33.9 bits (74), Expect = 3.9
Identities = 17/36 (47%), Positives = 23/36 (63%)
Frame = +1
Query: 523 LHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHGIL 630
L +GLL R TQN+D L + AG P+ ++E HG L
Sbjct: 89 LQREGLLKRLITQNVDGLHQAAGSPD--VIELHGSL 122
>UniRef50_A0PU12 Cluster: Sir2-like regulatory protein; n=1;
Mycobacterium ulcerans Agy99|Rep: Sir2-like regulatory
protein - Mycobacterium ulcerans (strain Agy99)
Length = 283
Score = 36.7 bits (81), Expect = 0.55
Identities = 14/24 (58%), Positives = 20/24 (83%)
Frame = +2
Query: 293 KIITLSGAGISTSAGIPDFRSPET 364
+I L+GAGIST +GIPD+R P++
Sbjct: 14 RIAVLTGAGISTDSGIPDYRGPDS 37
>UniRef50_A7SK95 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 323
Score = 36.7 bits (81), Expect = 0.55
Identities = 16/27 (59%), Positives = 20/27 (74%)
Frame = +2
Query: 293 KIITLSGAGISTSAGIPDFRSPETGLY 373
KI ++GAGIST +GI D+RS GLY
Sbjct: 62 KIFVITGAGISTESGIRDYRSEGKGLY 88
>UniRef50_Q9NRC8 Cluster: NAD-dependent deacetylase sirtuin-7; n=24;
Eumetazoa|Rep: NAD-dependent deacetylase sirtuin-7 -
Homo sapiens (Human)
Length = 400
Score = 36.7 bits (81), Expect = 0.55
Identities = 17/33 (51%), Positives = 24/33 (72%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQK 388
K ++ +GAGIST+A IPD+R P G++ LQK
Sbjct: 100 KYLVVYTGAGISTAASIPDYRGP-NGVWTLLQK 131
>UniRef50_Q8Y015 Cluster: NAD-dependent deacetylase; n=11;
Bacteria|Rep: NAD-dependent deacetylase - Ralstonia
solanacearum (Pseudomonas solanacearum)
Length = 246
Score = 36.7 bits (81), Expect = 0.55
Identities = 17/51 (33%), Positives = 29/51 (56%)
Frame = +2
Query: 269 WIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFE 421
WI++ ++++ L+GAG+S +G+P FR TGL+ +L A E
Sbjct: 17 WIEA--AERVMVLTGAGVSAESGVPTFRDALTGLWARFNPEDLATEAAYRE 65
>UniRef50_Q8FRV5 Cluster: NAD-dependent deacetylase 2; n=9;
Corynebacterineae|Rep: NAD-dependent deacetylase 2 -
Corynebacterium efficiens
Length = 254
Score = 36.7 bits (81), Expect = 0.55
Identities = 17/56 (30%), Positives = 33/56 (58%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFF 457
+ I +GAG+S +G+ +R PETG++ + PQA+ I+ + ++P+P +
Sbjct: 17 RNIEVFTGAGMSADSGLETYRDPETGVWSKV------DPQAMASIDAWARDPEPMW 66
>UniRef50_Q8FUC8 Cluster: NAD-dependent deacetylase 1; n=6;
Corynebacterium|Rep: NAD-dependent deacetylase 1 -
Corynebacterium efficiens
Length = 281
Score = 36.7 bits (81), Expect = 0.55
Identities = 15/38 (39%), Positives = 27/38 (71%)
Frame = +2
Query: 257 GIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGL 370
G+V+ +++ ++ ++GAG+ST +GIPD+RSP L
Sbjct: 9 GVVKLLEAG---SVLAVTGAGVSTDSGIPDYRSPRGSL 43
>UniRef50_Q5YR82 Cluster: Putative Sir2 family regulator; n=1;
Nocardia farcinica|Rep: Putative Sir2 family regulator -
Nocardia farcinica
Length = 248
Score = 36.3 bits (80), Expect = 0.72
Identities = 16/25 (64%), Positives = 19/25 (76%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSP 358
R +I L+GAGIST +GIPDFR P
Sbjct: 8 RSGRIGVLTGAGISTDSGIPDFRGP 32
>UniRef50_Q3F1F4 Cluster: SIR2 family protein; n=1; Bacillus
thuringiensis serovar israelensis ATCC 35646|Rep: SIR2
family protein - Bacillus thuringiensis serovar
israelensis ATCC 35646
Length = 241
Score = 36.3 bits (80), Expect = 0.72
Identities = 18/47 (38%), Positives = 29/47 (61%)
Frame = +2
Query: 296 IITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFR 436
I+ L+GAGIST +G+PD+RS GL+ + E+ A+ + F +
Sbjct: 15 IVVLTGAGISTDSGLPDYRS-NGGLWDGKKPEEISHFSAVGKPEFVK 60
>UniRef50_Q9FY91 Cluster: SIR2-family protein; n=12;
Magnoliophyta|Rep: SIR2-family protein - Arabidopsis
thaliana (Mouse-ear cress)
Length = 451
Score = 36.3 bits (80), Expect = 0.72
Identities = 15/31 (48%), Positives = 22/31 (70%)
Frame = +2
Query: 281 DRCKKIITLSGAGISTSAGIPDFRSPETGLY 373
++ ++ L+GAG+ST GIPD+RSP G Y
Sbjct: 166 EQSSRLTILTGAGVSTECGIPDYRSP-NGAY 195
>UniRef50_Q4QB33 Cluster: Sir2-family protein-like protein; n=4;
Trypanosomatidae|Rep: Sir2-family protein-like protein -
Leishmania major
Length = 320
Score = 36.3 bits (80), Expect = 0.72
Identities = 16/31 (51%), Positives = 21/31 (67%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYH 376
R + + L+GAG ST +GIPD+R P G YH
Sbjct: 19 RGRGCVVLTGAGCSTESGIPDYRGP-NGQYH 48
>UniRef50_Q6C8V5 Cluster: Similar to tr|Q9FY91 Arabidopsis thaliana
SIR2-family protein; n=1; Yarrowia lipolytica|Rep:
Similar to tr|Q9FY91 Arabidopsis thaliana SIR2-family
protein - Yarrowia lipolytica (Candida lipolytica)
Length = 411
Score = 36.3 bits (80), Expect = 0.72
Identities = 16/27 (59%), Positives = 21/27 (77%)
Frame = +2
Query: 293 KIITLSGAGISTSAGIPDFRSPETGLY 373
K L+GAGIST++G+PD+R P TG Y
Sbjct: 49 KTAILTGAGISTASGLPDYRGP-TGTY 74
>UniRef50_Q9NXA8 Cluster: NAD-dependent deacetylase sirtuin-5; n=28;
Coelomata|Rep: NAD-dependent deacetylase sirtuin-5 -
Homo sapiens (Human)
Length = 310
Score = 36.3 bits (80), Expect = 0.72
Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 3/78 (3%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPK---PF 454
+ K I+ +SGAG+S +G+P FR G + Q +L P A F NP F
Sbjct: 49 KAKHIVIISGAGVSAESGVPTFRG-AGGYWRKWQAQDLATPLA------FAHNPSRVWEF 101
Query: 455 FTLAKELFPGSFKPTISH 508
+ +E+ GS +P H
Sbjct: 102 YHYRREVM-GSKEPNAGH 118
>UniRef50_A7RMK8 Cluster: Predicted protein; n=5; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 273
Score = 35.9 bits (79), Expect = 0.96
Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 3/87 (3%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPK---PF 454
+ K I+ L+GAGIS +GIP FR GL+ +L P A F NP F
Sbjct: 24 KAKNILFLTGAGISAESGIPTFRG-AGGLWRTFSATDLATPGA------FHTNPSLVWEF 76
Query: 455 FTLAKELFPGSFKPTISHIS*DFYMRK 535
++ +E+ S KP +H + + +K
Sbjct: 77 YSYRREVVL-SKKPNPAHFAIAEFQKK 102
>UniRef50_A2DZ29 Cluster: Transcriptional regulator, Sir2 family
protein; n=4; Trichomonas vaginalis|Rep: Transcriptional
regulator, Sir2 family protein - Trichomonas vaginalis
G3
Length = 375
Score = 35.9 bits (79), Expect = 0.96
Identities = 19/39 (48%), Positives = 24/39 (61%)
Frame = +1
Query: 508 YFIRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
YF+ L ++G LLR YTQN+D L+ GI E L HG
Sbjct: 162 YFLENLEKRGKLLRLYTQNVDALD--VGILPEHLRCVHG 198
>UniRef50_Q3V7G9 Cluster: Putative cobalamin biosynthetic protein;
n=2; Acinetobacter|Rep: Putative cobalamin biosynthetic
protein - Acinetobacter sp. (strain ADP1)
Length = 233
Score = 35.5 bits (78), Expect = 1.3
Identities = 17/41 (41%), Positives = 26/41 (63%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQA 412
KK++ SGAG+S +GI FR + GL+ N + E+ P+A
Sbjct: 2 KKLVVFSGAGMSAESGIHTFRDHD-GLWENYRIEEVATPEA 41
>UniRef50_A6WG46 Cluster: Silent information regulator protein Sir2;
n=4; Actinomycetales|Rep: Silent information regulator
protein Sir2 - Kineococcus radiotolerans SRS30216
Length = 279
Score = 35.5 bits (78), Expect = 1.3
Identities = 15/35 (42%), Positives = 22/35 (62%), Gaps = 1/35 (2%)
Frame = +2
Query: 293 KIITLSGAGISTSAGIPDFRSPETGLY-HNLQKYE 394
+++ L GAG+ST +GIPD+R P L H Y+
Sbjct: 15 RVVVLEGAGMSTGSGIPDYRGPGGSLQRHTPMTYQ 49
>UniRef50_A1ZZG3 Cluster: NAD-dependent deacetylase; n=35;
Bacteria|Rep: NAD-dependent deacetylase - Microscilla
marina ATCC 23134
Length = 245
Score = 35.5 bits (78), Expect = 1.3
Identities = 17/40 (42%), Positives = 25/40 (62%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQ 409
+KI+ L+GAGIS +GI FR + GL+ N E+ P+
Sbjct: 17 QKIVVLTGAGISAESGISTFRDSD-GLWENHDVMEVASPE 55
>UniRef50_A5K3P4 Cluster: Putative uncharacterized protein; n=1;
Plasmodium vivax|Rep: Putative uncharacterized protein -
Plasmodium vivax
Length = 1259
Score = 35.5 bits (78), Expect = 1.3
Identities = 16/28 (57%), Positives = 22/28 (78%)
Frame = +2
Query: 296 IITLSGAGISTSAGIPDFRSPETGLYHN 379
I+ +GAGISTS+G+ DFR P TG++ N
Sbjct: 48 IVVHAGAGISTSSGLQDFRGP-TGIWTN 74
>UniRef50_Q7S223 Cluster: Putative uncharacterized protein
NCU05973.1; n=1; Neurospora crassa|Rep: Putative
uncharacterized protein NCU05973.1 - Neurospora crassa
Length = 334
Score = 35.5 bits (78), Expect = 1.3
Identities = 16/46 (34%), Positives = 28/46 (60%)
Frame = +2
Query: 275 KSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQA 412
K + +I+ + GAG+S ++G+P FR GL+ N + +L P+A
Sbjct: 14 KLAKADRILAICGAGLSAASGLPTFRG-VGGLWRNYEATDLATPEA 58
>UniRef50_Q607X6 Cluster: NAD-dependent deacetylase; n=1;
Methylococcus capsulatus|Rep: NAD-dependent deacetylase
- Methylococcus capsulatus
Length = 255
Score = 35.5 bits (78), Expect = 1.3
Identities = 15/40 (37%), Positives = 21/40 (52%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQ 409
+ I +GAG+S +GIP FR TG + N L P+
Sbjct: 15 RHIAVFTGAGVSAESGIPTFRDALTGFWENYDASTLASPE 54
>UniRef50_Q8ZT00 Cluster: NAD-dependent deacetylase 2; n=2; cellular
organisms|Rep: NAD-dependent deacetylase 2 - Pyrobaculum
aerophilum
Length = 249
Score = 35.5 bits (78), Expect = 1.3
Identities = 16/38 (42%), Positives = 23/38 (60%)
Frame = +2
Query: 299 ITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQA 412
+ +GAGIS +G+P FR P GL+ + EL P+A
Sbjct: 14 VVFTGAGISAESGVPTFRGP-GGLWERYKPEELATPEA 50
>UniRef50_UPI0000D573CE Cluster: PREDICTED: similar to CG11305-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG11305-PA - Tribolium castaneum
Length = 627
Score = 35.1 bits (77), Expect = 1.7
Identities = 15/35 (42%), Positives = 25/35 (71%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQK 388
+ + ++ +GAGIST+A IPD+R P G++ LQ+
Sbjct: 118 QAQHLVVYTGAGISTAAKIPDYRGP-NGIWTRLQQ 151
>UniRef50_A4UCE7 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 1122
Score = 35.1 bits (77), Expect = 1.7
Identities = 15/29 (51%), Positives = 21/29 (72%)
Frame = +1
Query: 508 YFIRLLHEKGLLLRHYTQNIDTLERGAGI 594
+FI L +KG L+R YTQNID +E+ G+
Sbjct: 272 HFISHLRDKGKLVRCYTQNIDEIEKRVGL 300
>UniRef50_Q8U1Q1 Cluster: NAD-dependent deacetylase; n=19; cellular
organisms|Rep: NAD-dependent deacetylase - Pyrococcus
furiosus
Length = 250
Score = 35.1 bits (77), Expect = 1.7
Identities = 20/50 (40%), Positives = 29/50 (58%)
Frame = +2
Query: 299 ITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPK 448
I +GAGIS +GIP FR + GL+ + EL P+A F+++PK
Sbjct: 16 IAFTGAGISAESGIPTFRGKD-GLWRKYRAEELATPEA------FKRDPK 58
>UniRef50_Q8CJM9 Cluster: NAD-dependent deacetylase 2; n=3;
Actinomycetales|Rep: NAD-dependent deacetylase 2 -
Streptomyces coelicolor
Length = 241
Score = 35.1 bits (77), Expect = 1.7
Identities = 15/26 (57%), Positives = 20/26 (76%)
Frame = +2
Query: 296 IITLSGAGISTSAGIPDFRSPETGLY 373
+ LSGAG+ST +GIPD+R P GL+
Sbjct: 7 VAILSGAGVSTDSGIPDYRGP-NGLW 31
Score = 33.1 bits (72), Expect = 6.7
Identities = 14/34 (41%), Positives = 22/34 (64%)
Frame = +1
Query: 523 LHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHG 624
L +G+ +R TQN+D L + AG+ K++E HG
Sbjct: 80 LERRGVPVRVLTQNVDGLHQLAGVSARKVLELHG 113
>UniRef50_Q8N6T7-2 Cluster: Isoform 2 of Q8N6T7 ; n=5;
Catarrhini|Rep: Isoform 2 of Q8N6T7 - Homo sapiens
(Human)
Length = 328
Score = 34.7 bits (76), Expect = 2.2
Identities = 17/42 (40%), Positives = 27/42 (64%)
Frame = +2
Query: 296 IITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFE 421
++ +GAGIST++GIPDFR P G++ ++ P+ FE
Sbjct: 47 VVFHTGAGISTASGIPDFRGPH-GVWTMEERGLAPKFDTTFE 87
>UniRef50_Q4RA56 Cluster: Chromosome undetermined SCAF24448, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF24448,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 85
Score = 34.7 bits (76), Expect = 2.2
Identities = 14/24 (58%), Positives = 19/24 (79%)
Frame = +2
Query: 257 GIVRWIKSDRCKKIITLSGAGIST 328
G+ ++IKS +CK II + GAGIST
Sbjct: 62 GVAQYIKSGKCKNIICMVGAGIST 85
>UniRef50_A6G0H3 Cluster: Silent information regulator protein Sir2;
n=1; Plesiocystis pacifica SIR-1|Rep: Silent information
regulator protein Sir2 - Plesiocystis pacifica SIR-1
Length = 288
Score = 34.7 bits (76), Expect = 2.2
Identities = 19/52 (36%), Positives = 28/52 (53%)
Frame = +2
Query: 293 KIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPK 448
K++ +GAGIS +GIP FR PE ++Y +PQ + F + PK
Sbjct: 30 KVVVTTGAGISAESGIPTFRGPEGYWTVGAKEY---RPQELATREAFGKLPK 78
>UniRef50_Q23A43 Cluster: Transcriptional regulator, Sir2 family
protein; n=2; Tetrahymena thermophila SB210|Rep:
Transcriptional regulator, Sir2 family protein -
Tetrahymena thermophila SB210
Length = 503
Score = 34.7 bits (76), Expect = 2.2
Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 1/57 (1%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELP-QPQAIFEINFFRQNPKPFF 457
KK++ L+GAGIS ++GIP FR G +K + Q + I NF + P F+
Sbjct: 125 KKVVFLTGAGISVASGIPTFRG--VGAAPLFEKDGVTYQNEEISTYNFMKNKPDIFW 179
>UniRef50_Q8N6T7 Cluster: Mono-ADP-ribosyltransferase sirtuin-6;
n=22; Euteleostomi|Rep: Mono-ADP-ribosyltransferase
sirtuin-6 - Homo sapiens (Human)
Length = 355
Score = 34.7 bits (76), Expect = 2.2
Identities = 17/42 (40%), Positives = 27/42 (64%)
Frame = +2
Query: 296 IITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFE 421
++ +GAGIST++GIPDFR P G++ ++ P+ FE
Sbjct: 47 VVFHTGAGISTASGIPDFRGPH-GVWTMEERGLAPKFDTTFE 87
>UniRef50_Q1D9X2 Cluster: Sir2 family protein; n=1; Myxococcus
xanthus DK 1622|Rep: Sir2 family protein - Myxococcus
xanthus (strain DK 1622)
Length = 287
Score = 34.3 bits (75), Expect = 2.9
Identities = 13/25 (52%), Positives = 18/25 (72%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPET 364
+ + L+GAG ST +GIPD+R P T
Sbjct: 27 RSTVVLTGAGCSTESGIPDYRGPGT 51
>UniRef50_A6PTK3 Cluster: Silent information regulator protein Sir2;
n=1; Victivallis vadensis ATCC BAA-548|Rep: Silent
information regulator protein Sir2 - Victivallis
vadensis ATCC BAA-548
Length = 248
Score = 34.3 bits (75), Expect = 2.9
Identities = 20/61 (32%), Positives = 33/61 (54%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAK 469
++ + +GAGIST +GI DFR + G+Y L+ + + I ++ F P F+ A
Sbjct: 13 RRTLAFTGAGISTLSGIRDFRG-KNGVY--LEPWHGKSVEEILSLDCFLAEPALFYGWAA 69
Query: 470 E 472
E
Sbjct: 70 E 70
>UniRef50_A0JXS0 Cluster: Silent information regulator protein Sir2
precursor; n=11; Actinomycetales|Rep: Silent information
regulator protein Sir2 precursor - Arthrobacter sp.
(strain FB24)
Length = 306
Score = 34.3 bits (75), Expect = 2.9
Identities = 15/36 (41%), Positives = 24/36 (66%), Gaps = 1/36 (2%)
Frame = +2
Query: 257 GIVRWIKSDRC-KKIITLSGAGISTSAGIPDFRSPE 361
G++R I+ + L+GAG+ST +GIPD+R P+
Sbjct: 30 GVLRGIRDAIAGTRFALLTGAGLSTDSGIPDYRGPD 65
>UniRef50_Q9RL35 Cluster: NAD-dependent deacetylase 1; n=8;
Actinomycetales|Rep: NAD-dependent deacetylase 1 -
Streptomyces coelicolor
Length = 299
Score = 34.3 bits (75), Expect = 2.9
Identities = 14/23 (60%), Positives = 18/23 (78%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFR 352
R ++ LSGAGIST +GIPD+R
Sbjct: 30 RAGGVLVLSGAGISTESGIPDYR 52
>UniRef50_A1I9S7 Cluster: NAD-dependent deacetylase; n=1; Candidatus
Desulfococcus oleovorans Hxd3|Rep: NAD-dependent
deacetylase - Candidatus Desulfococcus oleovorans Hxd3
Length = 273
Score = 33.9 bits (74), Expect = 3.9
Identities = 19/56 (33%), Positives = 29/56 (51%)
Frame = +2
Query: 308 SGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNPKPFFTLAKEL 475
SGAG+S +GIP FR P G++ L E+ Q + + +NP+ + EL
Sbjct: 24 SGAGVSAESGIPTFRDP-GGVWDRLNPAEVGDTQGL--LASLEKNPEKLVAMFMEL 76
>UniRef50_A0YUL1 Cluster: Peptidase C14, caspase catalytic subunit
p20; n=1; Lyngbya sp. PCC 8106|Rep: Peptidase C14,
caspase catalytic subunit p20 - Lyngbya sp. PCC 8106
Length = 699
Score = 33.9 bits (74), Expect = 3.9
Identities = 21/58 (36%), Positives = 33/58 (56%), Gaps = 7/58 (12%)
Frame = +3
Query: 84 SPQNVPPTTSMESLRNMFRDLD-VDDVRMYLA------LKLGLFSPQDLEPAEPPEKV 236
SP +P +S +SL+ RD++ V+D LA +KL +P++ P EPPEK+
Sbjct: 18 SPNTLPNGSSYKSLKGCVRDINQVEDFLNQLATRPNKIVKLTASNPENNSPVEPPEKL 75
>UniRef50_Q4P2A5 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 1036
Score = 33.9 bits (74), Expect = 3.9
Identities = 16/31 (51%), Positives = 21/31 (67%)
Frame = +1
Query: 502 FTYFIRLLHEKGLLLRHYTQNIDTLERGAGI 594
F F++ L ++G L R YTQNID LE AG+
Sbjct: 210 FHRFLKRLDDEGRLQRVYTQNIDGLEEKAGL 240
>UniRef50_Q885X7 Cluster: NAD-dependent deacetylase 2; n=4;
Pseudomonas|Rep: NAD-dependent deacetylase 2 -
Pseudomonas syringae pv. tomato
Length = 248
Score = 33.9 bits (74), Expect = 3.9
Identities = 14/25 (56%), Positives = 17/25 (68%)
Frame = +1
Query: 556 TQNIDTLERGAGIPEEKLVEAHGIL 630
TQN+D R AG P E+L+E HG L
Sbjct: 101 TQNVDGYHRAAGSPPERLIEIHGQL 125
>UniRef50_Q9I4E1 Cluster: NAD-dependent deacetylase 2; n=6;
Pseudomonadaceae|Rep: NAD-dependent deacetylase 2 -
Pseudomonas aeruginosa
Length = 256
Score = 33.9 bits (74), Expect = 3.9
Identities = 15/25 (60%), Positives = 17/25 (68%)
Frame = +1
Query: 556 TQNIDTLERGAGIPEEKLVEAHGIL 630
TQNID R AG P E+L+E HG L
Sbjct: 107 TQNIDGFHRQAGSPAERLIEIHGEL 131
>UniRef50_UPI0000D578DC Cluster: PREDICTED: similar to sirtuin 5
(silent mating type information regulation 2 homolog) 5;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
sirtuin 5 (silent mating type information regulation 2
homolog) 5 - Tribolium castaneum
Length = 254
Score = 33.5 bits (73), Expect = 5.1
Identities = 20/54 (37%), Positives = 29/54 (53%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQNP 445
+ + I+ L+GAG+S +GIP FR GL+ + +L P A FR NP
Sbjct: 18 QARSIVALTGAGVSAESGIPVFRG-AGGLWRTHRATDLATPTA------FRANP 64
>UniRef50_Q8N6T7-3 Cluster: Isoform 3 of Q8N6T7 ; n=2;
Catarrhini|Rep: Isoform 3 of Q8N6T7 - Homo sapiens
(Human)
Length = 187
Score = 33.5 bits (73), Expect = 5.1
Identities = 14/29 (48%), Positives = 21/29 (72%)
Frame = +2
Query: 296 IITLSGAGISTSAGIPDFRSPETGLYHNL 382
++ +GAGIST++GIPDFR L+ N+
Sbjct: 47 VVFHTGAGISTASGIPDFRDKLAELHGNM 75
>UniRef50_A7H7B6 Cluster: Silent information regulator protein Sir2;
n=2; Anaeromyxobacter|Rep: Silent information regulator
protein Sir2 - Anaeromyxobacter sp. Fw109-5
Length = 270
Score = 33.5 bits (73), Expect = 5.1
Identities = 16/44 (36%), Positives = 26/44 (59%)
Frame = +2
Query: 293 KIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEI 424
+++ L+GAG+S +GIP FR E G + + +PQ A E+
Sbjct: 18 RVVALTGAGVSAESGIPTFRGRE-GFWVVGSRNYMPQEMATHEM 60
>UniRef50_A6FYM4 Cluster: Sir2 family protein; n=1; Plesiocystis
pacifica SIR-1|Rep: Sir2 family protein - Plesiocystis
pacifica SIR-1
Length = 297
Score = 33.5 bits (73), Expect = 5.1
Identities = 12/25 (48%), Positives = 19/25 (76%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPET 364
++++ L+GAG ST +GIPD+R T
Sbjct: 34 RRVVALTGAGCSTESGIPDYRGEGT 58
>UniRef50_A1HLU5 Cluster: Silent information regulator protein Sir2;
n=1; Thermosinus carboxydivorans Nor1|Rep: Silent
information regulator protein Sir2 - Thermosinus
carboxydivorans Nor1
Length = 261
Score = 33.5 bits (73), Expect = 5.1
Identities = 14/26 (53%), Positives = 21/26 (80%)
Frame = +2
Query: 296 IITLSGAGISTSAGIPDFRSPETGLY 373
I+ +GAG+ST +G+PDFRS + GL+
Sbjct: 19 IVVFTGAGMSTESGLPDFRSKQ-GLW 43
>UniRef50_Q9VAQ1 Cluster: CG11305-PA; n=8; Coelomata|Rep: CG11305-PA
- Drosophila melanogaster (Fruit fly)
Length = 771
Score = 33.5 bits (73), Expect = 5.1
Identities = 16/35 (45%), Positives = 25/35 (71%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQK 388
+ K ++ +GAGIST+A IPD+R + G++ LQK
Sbjct: 122 QAKHLVCYTGAGISTAALIPDYRGSQ-GIWTLLQK 155
>UniRef50_Q5CYK0 Cluster: Bacterial-like Sir2 family protein; n=2;
Cryptosporidium|Rep: Bacterial-like Sir2 family protein
- Cryptosporidium parvum Iowa II
Length = 299
Score = 33.5 bits (73), Expect = 5.1
Identities = 15/29 (51%), Positives = 20/29 (68%)
Frame = +2
Query: 281 DRCKKIITLSGAGISTSAGIPDFRSPETG 367
D KKI+ ++GAG+S +GIP FRS G
Sbjct: 20 DSGKKILFITGAGLSLDSGIPLFRSESDG 48
Score = 32.7 bits (71), Expect = 8.9
Identities = 18/47 (38%), Positives = 24/47 (51%)
Frame = +1
Query: 556 TQNIDTLERGAGIPEEKLVEAHGILHITLSGIAARNTHWSLSKKGYL 696
TQNID L + P E ++E HG +H A N +S SK Y+
Sbjct: 116 TQNIDGLMQQTNCPRENIIEIHGRIHYL--RCANPNCDYSSSKFSYI 160
>UniRef50_Q6ZMU6 Cluster: CDNA FLJ16662 fis, clone TESTI4046240,
highly similar to Homo sapiens sirtuin 7; n=1; Homo
sapiens|Rep: CDNA FLJ16662 fis, clone TESTI4046240,
highly similar to Homo sapiens sirtuin 7 - Homo sapiens
(Human)
Length = 162
Score = 33.5 bits (73), Expect = 5.1
Identities = 17/47 (36%), Positives = 26/47 (55%)
Frame = +1
Query: 514 IRLLHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHGILHITLSGIA 654
I LHE+ L+ +QN D L +G+P + E HG ++I +S A
Sbjct: 3 ITRLHEQKLVQHVVSQNCDGLHLRSGLPRTAISELHGNMYIEVSSPA 49
>UniRef50_A6RLG6 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 553
Score = 33.5 bits (73), Expect = 5.1
Identities = 19/55 (34%), Positives = 32/55 (58%)
Frame = +1
Query: 523 LHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHGILHITLSGIAARNTHWSLSKK 687
+H G+ L YTQ ++ L AG P++ + GIL + + I+ R TH +LS++
Sbjct: 256 IHGIGIGLYPYTQFLNELNASAGTPDDHI----GILALEIMNISFRLTHSALSRE 306
>UniRef50_A4RCT8 Cluster: Putative uncharacterized protein; n=3;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 1040
Score = 33.5 bits (73), Expect = 5.1
Identities = 15/41 (36%), Positives = 24/41 (58%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQP 406
+ + I+ + GAG+S S+G+ FR P GL+ N + L P
Sbjct: 32 KSRNIVAIIGAGLSASSGLATFRGP-GGLWQNQDVFVLASP 71
>UniRef50_A6Q178 Cluster: Transcription regulator, Sir2 family; n=1;
Nitratiruptor sp. SB155-2|Rep: Transcription regulator,
Sir2 family - Nitratiruptor sp. (strain SB155-2)
Length = 234
Score = 33.1 bits (72), Expect = 6.7
Identities = 18/41 (43%), Positives = 25/41 (60%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQA 412
K I LSGAG+S +GIP FR + GL+ N+ E+ +A
Sbjct: 9 KNIYILSGAGLSAPSGIPTFR--DGGLWDNINIDEVATHEA 47
>UniRef50_Q175I4 Cluster: Chromatin regulatory protein sir2; n=3;
Coelomata|Rep: Chromatin regulatory protein sir2 - Aedes
aegypti (Yellowfever mosquito)
Length = 720
Score = 33.1 bits (72), Expect = 6.7
Identities = 17/53 (32%), Positives = 27/53 (50%), Gaps = 1/53 (1%)
Frame = +1
Query: 523 LHEKGLLLRHYTQNIDTLERGAGIPEEKLVEAHGILHITLSGIAARNT-HWSL 678
LH +G+L +QN D L +G+P L E HG +++ + N +W L
Sbjct: 136 LHRRGILKHVVSQNCDGLHLRSGLPRFCLSEVHGNMYVEVCKNCKPNVEYWRL 188
>UniRef50_Q6CHN4 Cluster: Similar to tr|Q96QF7 Homo sapiens NAAR1
Putative nuclear protein; n=1; Yarrowia lipolytica|Rep:
Similar to tr|Q96QF7 Homo sapiens NAAR1 Putative nuclear
protein - Yarrowia lipolytica (Candida lipolytica)
Length = 323
Score = 33.1 bits (72), Expect = 6.7
Identities = 14/55 (25%), Positives = 27/55 (49%)
Frame = +2
Query: 272 IKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFR 436
+ D ++++ +G ++ G PD+ GL+ L Y++P+ A E N R
Sbjct: 81 LNDDNLPELLSAAGQSLAAFEGSPDYAKVSNGLHSALPHYDVPKAMANVENNLGR 135
>UniRef50_Q882K4 Cluster: NAD-dependent deacetylase 3; n=5;
Pseudomonas|Rep: NAD-dependent deacetylase 3 -
Pseudomonas syringae pv. tomato
Length = 281
Score = 33.1 bits (72), Expect = 6.7
Identities = 12/24 (50%), Positives = 19/24 (79%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPE 361
K + ++GAGIST++GIPD+R +
Sbjct: 20 KSFLVVTGAGISTASGIPDYRDKD 43
>UniRef50_UPI000050FCF4 Cluster: COG0846: NAD-dependent protein
deacetylases, SIR2 family; n=1; Brevibacterium linens
BL2|Rep: COG0846: NAD-dependent protein deacetylases,
SIR2 family - Brevibacterium linens BL2
Length = 309
Score = 32.7 bits (71), Expect = 8.9
Identities = 11/19 (57%), Positives = 17/19 (89%)
Frame = +2
Query: 305 LSGAGISTSAGIPDFRSPE 361
L+GAG+ST +G+PD+R P+
Sbjct: 44 LTGAGMSTDSGVPDYRGPD 62
>UniRef50_A6TNA0 Cluster: Silent information regulator protein Sir2;
n=1; Alkaliphilus metalliredigens QYMF|Rep: Silent
information regulator protein Sir2 - Alkaliphilus
metalliredigens QYMF
Length = 249
Score = 32.7 bits (71), Expect = 8.9
Identities = 18/53 (33%), Positives = 30/53 (56%)
Frame = +2
Query: 284 RCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQAIFEINFFRQN 442
+ K + L+GAG+ T + IPDFRS E G + ++ P+ + I+ F +N
Sbjct: 23 KSKDTVILTGAGMDTESNIPDFRS-EKGWWRSI------DPRTVANIDTFYEN 68
>UniRef50_Q55DB0 Cluster: NAD(+)-dependent deacetylase, silent
information regulator protein (Sir2) family protein;
n=1; Dictyostelium discoideum AX4|Rep: NAD(+)-dependent
deacetylase, silent information regulator protein (Sir2)
family protein - Dictyostelium discoideum AX4
Length = 346
Score = 32.7 bits (71), Expect = 8.9
Identities = 14/23 (60%), Positives = 16/23 (69%)
Frame = +1
Query: 556 TQNIDTLERGAGIPEEKLVEAHG 624
TQN+D L A +P EKLVE HG
Sbjct: 131 TQNVDALHLKAKVPIEKLVEVHG 153
>UniRef50_Q4UH74 Cluster: Sir2-like histone deacetylase, putative;
n=2; Theileria|Rep: Sir2-like histone deacetylase,
putative - Theileria annulata
Length = 928
Score = 32.7 bits (71), Expect = 8.9
Identities = 12/17 (70%), Positives = 15/17 (88%)
Frame = +2
Query: 308 SGAGISTSAGIPDFRSP 358
+GAG+ST +GIPDFR P
Sbjct: 54 TGAGVSTGSGIPDFRGP 70
>UniRef50_Q2U9Y7 Cluster: Sirtuin 4 and related class II sirtuins;
n=10; Pezizomycotina|Rep: Sirtuin 4 and related class II
sirtuins - Aspergillus oryzae
Length = 407
Score = 32.7 bits (71), Expect = 8.9
Identities = 18/53 (33%), Positives = 29/53 (54%)
Frame = +2
Query: 233 SFG*SQPYGIVRWIKSDRCKKIITLSGAGISTSAGIPDFRSPETGLYHNLQKY 391
SF + P +R + R + + L+GAGIS ++G+ D+R E G Y + Y
Sbjct: 63 SFLTAPPSPYLRGVDVGRYSQTVLLTGAGISVASGLSDYRG-ENGTYVTNKTY 114
>UniRef50_A4RNA8 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 279
Score = 32.7 bits (71), Expect = 8.9
Identities = 20/63 (31%), Positives = 35/63 (55%), Gaps = 4/63 (6%)
Frame = +3
Query: 93 NVPPTTSMESLRNMFRDLD-VDDVRMYLALKLGL---FSPQDLEPAEPPEKVLDEVSLMV 260
N+P ++ +L N+F+DL+ + DVR+ + G F+ D + E K +++V LM
Sbjct: 175 NIPYESTDAALNNLFQDLEGLKDVRIAVDRSTGWPRGFAHADFKDVESATKAVEKVKLME 234
Query: 261 LSG 269
L G
Sbjct: 235 LMG 237
>UniRef50_Q9I4L0 Cluster: NAD-dependent deacetylase 1; n=10;
Bacteria|Rep: NAD-dependent deacetylase 1 - Pseudomonas
aeruginosa
Length = 250
Score = 32.7 bits (71), Expect = 8.9
Identities = 14/41 (34%), Positives = 22/41 (53%)
Frame = +2
Query: 290 KKIITLSGAGISTSAGIPDFRSPETGLYHNLQKYELPQPQA 412
++++ +GAG+S +GIP FR GL+ L P A
Sbjct: 12 RRLVIFTGAGVSAESGIPTFRDALGGLWARYDPAALATPAA 52
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 755,521,737
Number of Sequences: 1657284
Number of extensions: 16181529
Number of successful extensions: 40925
Number of sequences better than 10.0: 237
Number of HSP's better than 10.0 without gapping: 39304
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 40846
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 55371905986
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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