BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= NV021283 (749 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_P31939 Cluster: Bifunctional purine biosynthesis protei... 141 1e-32 UniRef50_Q4SHT8 Cluster: Chromosome 5 SCAF14581, whole genome sh... 121 2e-26 UniRef50_Q73LG8 Cluster: Phosphoribosylaminoimidazolecarboxamide... 97 3e-19 UniRef50_Q550I9 Cluster: AICAR transformylase / IMP cyclohydrola... 96 7e-19 UniRef50_P74741 Cluster: Bifunctional purine biosynthesis protei... 96 7e-19 UniRef50_Q9RW01 Cluster: Bifunctional purine biosynthesis protei... 93 5e-18 UniRef50_Q2JR47 Cluster: Bifunctional purine biosynthesis protei... 93 7e-18 UniRef50_Q2JI00 Cluster: Bifunctional purine biosynthesis protei... 93 9e-18 UniRef50_A5E8X1 Cluster: Phosphoribosylaminoimidazolecarboxamide... 92 2e-17 UniRef50_Q8ZAR3 Cluster: Bifunctional purine biosynthesis protei... 91 2e-17 UniRef50_Q7X311 Cluster: Putative AICAR transformylase; n=1; unc... 90 5e-17 UniRef50_O67775 Cluster: Bifunctional purine biosynthesis protei... 89 8e-17 UniRef50_A7HM64 Cluster: IMP cyclohydrolase; n=1; Fervidobacteri... 89 1e-16 UniRef50_A7DF55 Cluster: Phosphoribosylaminoimidazolecarboxamide... 88 2e-16 UniRef50_A0JTW4 Cluster: Phosphoribosylaminoimidazolecarboxamide... 88 2e-16 UniRef50_Q1V178 Cluster: Bifunctional purine biosynthesis protei... 87 6e-16 UniRef50_Q8PYG4 Cluster: Formyltransferase phosphoribosylaminoim... 87 6e-16 UniRef50_UPI00015BCE7E Cluster: UPI00015BCE7E related cluster; n... 86 8e-16 UniRef50_A1K9K5 Cluster: Phosphoribosylaminoimidazolecarboxamide... 86 1e-15 UniRef50_Q9FPL3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 85 2e-15 UniRef50_Q83EI4 Cluster: Phosphoribosylaminoimidazolecarboxamide... 84 3e-15 UniRef50_Q0YKD5 Cluster: IMP cyclohydrolase; n=2; Geobacter|Rep:... 84 3e-15 UniRef50_Q9PC10 Cluster: Bifunctional purine biosynthesis protei... 84 3e-15 UniRef50_P12048 Cluster: Bifunctional purine biosynthesis protei... 84 4e-15 UniRef50_A2SS05 Cluster: Phosphoribosylaminoimidazolecarboxamide... 83 5e-15 UniRef50_P67543 Cluster: Bifunctional purine biosynthesis protei... 83 5e-15 UniRef50_Q8CXK7 Cluster: Bifunctional purine biosynthesis protei... 82 2e-14 UniRef50_Q95QQ5 Cluster: Putative uncharacterized protein; n=2; ... 81 2e-14 UniRef50_P43852 Cluster: Bifunctional purine biosynthesis protei... 81 2e-14 UniRef50_A6G003 Cluster: Bifunctional phosphoribosylaminoimidazo... 81 4e-14 UniRef50_Q9F1T4 Cluster: Bifunctional purine biosynthesis protei... 80 7e-14 UniRef50_A7BET6 Cluster: Putative uncharacterized protein; n=1; ... 79 9e-14 UniRef50_Q8XMK2 Cluster: Bifunctional purine biosynthesis protei... 79 2e-13 UniRef50_Q8F3W6 Cluster: Bifunctional purine biosynthesis protei... 78 3e-13 UniRef50_Q9PNY2 Cluster: Bifunctional purine biosynthesis protei... 78 3e-13 UniRef50_Q8G6B1 Cluster: Bifunctional purine biosynthesis protei... 78 3e-13 UniRef50_Q6L122 Cluster: Phosphoribosylaminoimidazolecarboxamide... 77 6e-13 UniRef50_Q7MUT5 Cluster: Phosphoribosylaminoimidazolecarboxamide... 74 3e-12 UniRef50_Q7VRP9 Cluster: Phosphoribosylaminoimidazolecarboxamide... 73 6e-12 UniRef50_Q316G8 Cluster: Phosphoribosylaminoimidazolecarboxamide... 73 1e-11 UniRef50_Q8A155 Cluster: Bifunctional purine biosynthesis protei... 73 1e-11 UniRef50_A7I7L2 Cluster: Phosphoribosylaminoimidazolecarboxamide... 70 7e-11 UniRef50_Q83GZ1 Cluster: Phosphoribosylaminoimidazolecarboxamide... 69 1e-10 UniRef50_A1G3C3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 67 4e-10 UniRef50_A7PK27 Cluster: Chromosome chr15 scaffold_19, whole gen... 60 4e-08 UniRef50_Q8D244 Cluster: Bifunctional purine biosynthesis protei... 60 4e-08 UniRef50_Q89B23 Cluster: Bifunctional purine biosynthesis protei... 60 4e-08 UniRef50_A1IEQ8 Cluster: IMP cyclohydrolase; n=1; Candidatus Des... 59 1e-07 UniRef50_Q6MIZ2 Cluster: IMP cyclohydrolase; n=1; Bdellovibrio b... 57 5e-07 UniRef50_A4MAE3 Cluster: Phosphoribosylaminoimidazolecarboxamide... 55 2e-06 UniRef50_Q9X0X6 Cluster: Bifunctional purine biosynthesis protei... 55 2e-06 UniRef50_A5B1A5 Cluster: DNA-directed RNA polymerase; n=1; Vitis... 50 6e-05 UniRef50_A5B3D8 Cluster: DNA-directed RNA polymerase; n=1; Vitis... 46 8e-04 UniRef50_A6PRZ4 Cluster: Phosphoribosylaminoimidazolecarboxamide... 40 0.049 UniRef50_A6DLC7 Cluster: IMP cyclohydrolase; n=1; Lentisphaera a... 38 0.26 UniRef50_Q0W4V4 Cluster: Predicted ABC-type transport system, pe... 37 0.61 UniRef50_A1FWI7 Cluster: Putative uncharacterized protein precur... 36 1.4 UniRef50_Q08W60 Cluster: Putative uncharacterized protein; n=1; ... 35 1.9 UniRef50_Q9HS43 Cluster: Phosphoribosylaminoimidazole-succinocar... 35 1.9 UniRef50_Q4P5L9 Cluster: Putative uncharacterized protein; n=1; ... 34 3.3 UniRef50_Q6AGB7 Cluster: Flagellar hook-associated protein 3; n=... 34 4.3 UniRef50_Q337Q0 Cluster: Expressed protein; n=1; Oryza sativa (j... 33 5.7 UniRef50_Q54WL3 Cluster: Putative uncharacterized protein; n=1; ... 33 5.7 UniRef50_Q4T8W0 Cluster: Chromosome undetermined SCAF7713, whole... 33 7.5 UniRef50_Q0ICG1 Cluster: Lipase/esterase family protein; n=1; Sy... 33 7.5 UniRef50_Q8LNV5 Cluster: Putative uncharacterized protein OSJNBa... 33 7.5 UniRef50_Q5FJY6 Cluster: Carbamoyl-phosphate synthase large subu... 33 9.9 UniRef50_Q0SCZ3 Cluster: Fructuronate reductase; n=1; Rhodococcu... 33 9.9 UniRef50_A3X0C9 Cluster: Putative uncharacterized protein; n=1; ... 33 9.9 UniRef50_Q9AXF7 Cluster: RNA stability factor MCA1; n=1; Chlamyd... 33 9.9 UniRef50_Q5C3G2 Cluster: SJCHGC02321 protein; n=1; Schistosoma j... 33 9.9 UniRef50_Q6CDD1 Cluster: Similarities with DEHA0F12342g Debaryom... 33 9.9 UniRef50_Q6C2W2 Cluster: Similarity; n=1; Yarrowia lipolytica|Re... 33 9.9 >UniRef50_P31939 Cluster: Bifunctional purine biosynthesis protein PURH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)]; n=105; cellular organisms|Rep: Bifunctional purine biosynthesis protein PURH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)] - Homo sapiens (Human) Length = 592 Score = 141 bits (342), Expect = 1e-32 Identities = 64/80 (80%), Positives = 71/80 (88%) Frame = +1 Query: 508 QQYSPGQAQLTLRYGMNPHQKPAQVFTTRDSLPITTLNGAPGFINLCDALNAWQLVKELK 687 +QYS G +Q+ LRYGMNPHQ PAQ++T + LPIT LNGAPGFINLCDALNAWQLVKELK Sbjct: 195 KQYSKGVSQMPLRYGMNPHQTPAQLYTLQPKLPITVLNGAPGFINLCDALNAWQLVKELK 254 Query: 688 EALSLPAAASFKHVSPAGAA 747 EAL +PAAASFKHVSPAGAA Sbjct: 255 EALGIPAAASFKHVSPAGAA 274 Score = 119 bits (287), Expect = 7e-26 Identities = 56/82 (68%), Positives = 66/82 (80%) Frame = +1 Query: 10 GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQED 189 GL L+ASGGTA++LR+AGL V+DVS++T PEMLGGRVKTLHPAVHAGILAR D D Sbjct: 28 GLNLVASGGTAKALRDAGLAVRDVSELTGFPEMLGGRVKTLHPAVHAGILARNIPEDNAD 87 Query: 190 MKRQKYEMISVVVCNLYPFVQT 255 M R + +I VV CNLYPFV+T Sbjct: 88 MARLDFNLIRVVACNLYPFVKT 109 Score = 81.4 bits (192), Expect = 2e-14 Identities = 38/65 (58%), Positives = 47/65 (72%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRS 511 AKNH RVTVVC+P DY V E++ ++ T+L TR++LALKAFTHT+ YD AISDYFR Sbjct: 136 AKNHARVTVVCEPEDYVVVSTEMQSSESKDTSLETRRQLALKAFTHTAQYDEAISDYFRK 195 Query: 512 NTRPG 526 G Sbjct: 196 QYSKG 200 Score = 43.6 bits (98), Expect = 0.005 Identities = 28/67 (41%), Positives = 36/67 (53%), Gaps = 5/67 (7%) Frame = +3 Query: 240 PVRPDVSKPDVTVADAVENIDIGGVTLLRAQPR-----TTTGSPSSVTRPTTML*SKKSK 404 P V+ P VTV +AVE IDIGGVTLLRA + T P +T + S +SK Sbjct: 105 PFVKTVASPGVTVEEAVEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVVVSTEMQSSESK 164 Query: 405 RTNIIRR 425 T++ R Sbjct: 165 DTSLETR 171 >UniRef50_Q4SHT8 Cluster: Chromosome 5 SCAF14581, whole genome shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 5 SCAF14581, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 628 Score = 121 bits (291), Expect = 2e-26 Identities = 56/84 (66%), Positives = 69/84 (82%) Frame = +1 Query: 4 ECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQ 183 + GL L+ASGGTA++LR+AG V+DVS++T PEMLGGRVKTLHPAVH GILAR S +D Sbjct: 20 DVGLSLVASGGTAKTLRDAGWAVRDVSELTGHPEMLGGRVKTLHPAVHGGILARKSPADT 79 Query: 184 EDMKRQKYEMISVVVCNLYPFVQT 255 DM++ Y +I VVVCNLYPFV+T Sbjct: 80 ADMEKLGYSLIRVVVCNLYPFVKT 103 Score = 113 bits (272), Expect = 4e-24 Identities = 49/67 (73%), Positives = 58/67 (86%) Frame = +1 Query: 547 YGMNPHQKPAQVFTTRDSLPITTLNGAPGFINLCDALNAWQLVKELKEALSLPAAASFKH 726 YGMNPHQ PAQ++T R +LP+ +NG+PGFINLCDALNAWQLV+EL +AL + AA SFKH Sbjct: 191 YGMNPHQAPAQLYTLRPALPLRVVNGSPGFINLCDALNAWQLVRELSKALGVAAATSFKH 250 Query: 727 VSPAGAA 747 VSPAGAA Sbjct: 251 VSPAGAA 257 Score = 46.4 bits (105), Expect = 8e-04 Identities = 41/102 (40%), Positives = 49/102 (48%), Gaps = 1/102 (0%) Frame = +3 Query: 240 PVRPDVSKPDVTVADAVENIDIGGVTLLRAQPRTTTGSPSSVTRPTTML*SKKSKRTNII 419 P VS P VTV DAVE IDIGGVTLLRA + + R T + + + Sbjct: 99 PFVKTVSNPSVTVEDAVEQIDIGGVTLLRA-------AAKNHARVTVV--CDPADYPRVA 149 Query: 420 RRLWAQG-RD*P*RRSLILRTMTSPYRTTSAAILARASPTDL 542 + G RD P R L + T PYRTTS A A P+ L Sbjct: 150 EEMEGSGSRDTPSRTRL---STTRPYRTTSGDSSAVAFPSCL 188 Score = 43.6 bits (98), Expect = 0.005 Identities = 20/36 (55%), Positives = 24/36 (66%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTR 439 AKNH RVTVVCDPADY V +E++ + T TR Sbjct: 130 AKNHARVTVVCDPADYPRVAEEMEGSGSRDTPSRTR 165 >UniRef50_Q73LG8 Cluster: Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; n=2; Bacteria|Rep: Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase - Treponema denticola Length = 533 Score = 97.5 bits (232), Expect = 3e-19 Identities = 43/82 (52%), Positives = 61/82 (74%) Frame = +1 Query: 10 GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQED 189 G IASGGTA++L+ AG+ V++VS+ T +PE+LGGRVKTLHP +H GILAR + D+ + Sbjct: 25 GYDFIASGGTAKTLQEAGIKVKEVSEYTSSPEILGGRVKTLHPMIHGGILARDTKEDRAE 84 Query: 190 MKRQKYEMISVVVCNLYPFVQT 255 +K + I +V+ NLYPF +T Sbjct: 85 LKALGFSGIDIVIANLYPFEKT 106 Score = 61.3 bits (142), Expect = 2e-08 Identities = 31/63 (49%), Positives = 42/63 (66%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRS 511 AKN+ RVTV+CDPADYD V EI+ K + +L R+RLA+KAF + YD AI+ + Sbjct: 133 AKNYSRVTVICDPADYDEVSSEIE--KTGEISLSLRKRLAIKAFDLCTRYDAAITSWLSG 190 Query: 512 NTR 520 +R Sbjct: 191 LSR 193 Score = 41.5 bits (93), Expect = 0.021 Identities = 18/30 (60%), Positives = 21/30 (70%) Frame = +3 Query: 240 PVRPDVSKPDVTVADAVENIDIGGVTLLRA 329 P +S PD T +D +ENIDIGGV LLRA Sbjct: 102 PFEKTISSPDSTESDCIENIDIGGVALLRA 131 Score = 39.9 bits (89), Expect = 0.065 Identities = 32/80 (40%), Positives = 41/80 (51%), Gaps = 4/80 (5%) Frame = +1 Query: 520 PGQAQLTLRYGMNPHQKPAQVFTTRDSL-PI--TTLNG-APGFINLCDALNAWQLVKELK 687 PGQ LRYG NPHQK A ++T P+ L G A + N+ DA AW+ V Sbjct: 210 PGQ---DLRYGENPHQK-AWLYTNEPKAGPLGGKVLQGKALSYNNILDADAAWRAV---- 261 Query: 688 EALSLPAAASFKHVSPAGAA 747 + PAA KH++P G A Sbjct: 262 SMFTKPAAVVVKHLTPCGLA 281 >UniRef50_Q550I9 Cluster: AICAR transformylase / IMP cyclohydrolase; n=2; Dictyostelium discoideum|Rep: AICAR transformylase / IMP cyclohydrolase - Dictyostelium discoideum AX4 Length = 542 Score = 96.3 bits (229), Expect = 7e-19 Identities = 48/86 (55%), Positives = 60/86 (69%), Gaps = 1/86 (1%) Frame = +1 Query: 1 SECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLS-DS 177 S G LI++GGTA+SL + GL VQ VSD+T PEML GRVKTLHP +H G+LAR Sbjct: 21 SSKGFNLISTGGTAKSLVDNGLKVQQVSDVTEYPEMLDGRVKTLHPKIHGGLLARPELAH 80 Query: 178 DQEDMKRQKYEMISVVVCNLYPFVQT 255 Q D+ + + IS+VV NLYPFV+T Sbjct: 81 HQADLNKYNIKPISIVVVNLYPFVET 106 Score = 46.0 bits (104), Expect = 0.001 Identities = 24/63 (38%), Positives = 35/63 (55%), Gaps = 5/63 (7%) Frame = +2 Query: 329 TAKNHDRVTVVCDPADYDAVVKEIKE-----NKHHQTTLGTRQRLALKAFTHTSDYDLAI 493 ++KN V ++ DP+DY + + I+ N TL R++LALKAF H YD A+ Sbjct: 132 SSKNFQNVLIIVDPSDYKWIGERIQSSTDSTNVLSSITLEERKKLALKAFQHGCSYDAAV 191 Query: 494 SDY 502 S Y Sbjct: 192 SQY 194 Score = 37.1 bits (82), Expect = 0.46 Identities = 17/33 (51%), Positives = 22/33 (66%) Frame = +3 Query: 240 PVRPDVSKPDVTVADAVENIDIGGVTLLRAQPR 338 P VSK T+ +A+ENIDIGG TL+RA + Sbjct: 102 PFVETVSKESTTLEEAIENIDIGGHTLIRASSK 134 >UniRef50_P74741 Cluster: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)]; n=49; root|Rep: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)] - Synechocystis sp. (strain PCC 6803) Length = 511 Score = 96.3 bits (229), Expect = 7e-19 Identities = 48/86 (55%), Positives = 60/86 (69%), Gaps = 1/86 (1%) Frame = +1 Query: 1 SECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLS-DS 177 +E LI+SGGTA++L+ AG+ V VSD T APE+LGGRVKTLHP +H GILAR S Sbjct: 24 NEFQFDLISSGGTAKTLKEAGVPVTKVSDYTGAPEILGGRVKTLHPRIHGGILARRDLPS 83 Query: 178 DQEDMKRQKYEMISVVVCNLYPFVQT 255 DQ D++ + +VV NLYPF QT Sbjct: 84 DQADLEANDIRPLDLVVVNLYPFEQT 109 Score = 43.6 bits (98), Expect = 0.005 Identities = 23/59 (38%), Positives = 36/59 (61%) Frame = +2 Query: 329 TAKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYF 505 TAKN TV+ +P Y+A ++ ++E + L RQ+ A +AF T+ YD AI++YF Sbjct: 135 TAKNFAHTTVLTNPNQYEAYLQALQE--QGEIPLALRQQFAGEAFALTNAYDQAIANYF 191 Score = 39.5 bits (88), Expect = 0.086 Identities = 17/30 (56%), Positives = 22/30 (73%) Frame = +3 Query: 240 PVRPDVSKPDVTVADAVENIDIGGVTLLRA 329 P ++KP VTVA+AVE IDIGG ++RA Sbjct: 105 PFEQTIAKPGVTVAEAVEQIDIGGPAMIRA 134 Score = 35.1 bits (77), Expect = 1.9 Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 4/79 (5%) Frame = +1 Query: 523 GQAQLTLRYGMNPHQKPAQVFTTRDS---LPITTLNGAP-GFINLCDALNAWQLVKELKE 690 G + LRYG NPHQ T R++ L G + NL D A +++ E Sbjct: 206 GTLRQPLRYGENPHQSAGWYQTGREATGWAKAEKLQGKELSYNNLVDLEAARRIINEFD- 264 Query: 691 ALSLPAAASFKHVSPAGAA 747 + PAA KH +P G A Sbjct: 265 -VREPAAVILKHTNPCGVA 282 >UniRef50_Q9RW01 Cluster: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)]; n=3; Bacteria|Rep: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)] - Deinococcus radiodurans Length = 510 Score = 93.5 bits (222), Expect = 5e-18 Identities = 75/256 (29%), Positives = 109/256 (42%), Gaps = 10/256 (3%) Frame = +1 Query: 10 GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQED 189 G +L+++GGT +L AG+ V+ VSD+T PEML GRVKTLHPA+H GILAR Sbjct: 26 GWELLSTGGTFATLSGAGIPVRQVSDVTGFPEMLDGRVKTLHPAIHGGILARREAGHLGQ 85 Query: 190 MKRQKYEMISVVVCNLYPFVQTYL--XXXXXXXXXXXXXXXAA*PSCAHSQEXXXXXXXX 363 + Q I +V NLYPF +T A S A + + Sbjct: 86 LAAQDIGTIDLVCVNLYPFRETVARGAPDPEVIENIDIGGPAMIRSAAKNHDAVLVLVDP 145 Query: 364 XXXXXXCCSQRN--QREQTSSDDFGHKAEISPEGVHSYFGL*PRHIGLLPQQYSPGQAQL 537 + + +R + ++ + H +E G LP+ S + Sbjct: 146 ADYALALQDEVSPAERRRLAAKAYRHTSEYDAAITAYLSGESDELPTQLPEHLSLDLTRT 205 Query: 538 T-LRYGMNPHQKPAQVFTTRDS----LPITTLNGAP-GFINLCDALNAWQLVKELKEALS 699 +RYG NPHQ P ++ ++ + + G P F N DA AW L +EL Sbjct: 206 AQVRYGENPHQ-PGAIYRWGNARGPVIDAQVVAGKPMSFNNYADADAAWSLCQELAAQEQ 264 Query: 700 LPAAASFKHVSPAGAA 747 + KH +P G A Sbjct: 265 GAVCVAVKHANPCGVA 280 Score = 50.8 bits (116), Expect = 4e-05 Identities = 26/57 (45%), Positives = 36/57 (63%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDY 502 AKNHD V V+ DPADY +++ + + R+RLA KA+ HTS+YD AI+ Y Sbjct: 133 AKNHDAVLVLVDPADYALALQD-------EVSPAERRRLAAKAYRHTSEYDAAITAY 182 >UniRef50_Q2JR47 Cluster: Bifunctional purine biosynthesis protein PurH; n=12; Bacteria|Rep: Bifunctional purine biosynthesis protein PurH - Synechococcus sp. (strain JA-3-3Ab) (Cyanobacteria bacteriumYellowstone A-Prime) Length = 537 Score = 93.1 bits (221), Expect = 7e-18 Identities = 47/85 (55%), Positives = 59/85 (69%), Gaps = 1/85 (1%) Frame = +1 Query: 4 ECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLS-DSD 180 E G QL++SGGTA++L AG+ V VS+ T APE+LGGRVKTLHP +H GILARL D Sbjct: 30 EHGFQLLSSGGTAKALSEAGIPVTPVSEHTGAPEILGGRVKTLHPRIHGGILARLERRED 89 Query: 181 QEDMKRQKYEMISVVVCNLYPFVQT 255 + D++ I +VV N YPF QT Sbjct: 90 RADLEALGIPPIQLVVVNFYPFEQT 114 Score = 38.7 bits (86), Expect = 0.15 Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 2/68 (2%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYF-R 508 AKN+ VTV+ DP+ Y ++ + L R + A +AF YD AI DY R Sbjct: 141 AKNYPHVTVLTDPSQYPQYLQLLSSPSSEAERLAFRFQCARRAFEQVLAYDRAIVDYLTR 200 Query: 509 SN-TRPGK 529 S +RP + Sbjct: 201 SELSRPSQ 208 >UniRef50_Q2JI00 Cluster: Bifunctional purine biosynthesis protein PurH; n=1; Synechococcus sp. JA-2-3B'a(2-13)|Rep: Bifunctional purine biosynthesis protein PurH - Synechococcus sp. (strain JA-2-3B'a(2-13)) (Cyanobacteria bacteriumYellowstone B-Prime) Length = 577 Score = 92.7 bits (220), Expect = 9e-18 Identities = 48/85 (56%), Positives = 59/85 (69%), Gaps = 1/85 (1%) Frame = +1 Query: 4 ECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDS-D 180 E G QL++SGGTA++L AG+ V VS T APE+LGGRVKTLHP +H GILARL S D Sbjct: 38 EHGFQLLSSGGTAKALSEAGIPVTPVSAHTGAPEILGGRVKTLHPRIHGGILARLECSED 97 Query: 181 QEDMKRQKYEMISVVVCNLYPFVQT 255 + D++ I +VV N YPF QT Sbjct: 98 RADLEALGIPPIQLVVVNFYPFEQT 122 Score = 32.7 bits (71), Expect = 9.9 Identities = 19/57 (33%), Positives = 27/57 (47%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDY 502 AKN+ VTV+ DP+ Y ++ + L R + A +AF YD AI Y Sbjct: 149 AKNYPYVTVLTDPSQYPRYLQLLSGAYGETERLAFRFQCARRAFEQVLAYDRAIVTY 205 >UniRef50_A5E8X1 Cluster: Phosphoribosylaminoimidazolecarboxamide formyltransferase /IMP cyclohydrolase; n=4; Bacteria|Rep: Phosphoribosylaminoimidazolecarboxamide formyltransferase /IMP cyclohydrolase - Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182) Length = 530 Score = 91.9 bits (218), Expect = 2e-17 Identities = 45/83 (54%), Positives = 60/83 (72%), Gaps = 1/83 (1%) Frame = +1 Query: 10 GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILA-RLSDSDQE 186 G++LI++GGTA+++ +AGL V+DVSD+T PEM+ GRVKTLHP VH G+LA R +D E Sbjct: 32 GIELISTGGTAKAIADAGLKVKDVSDLTGFPEMMDGRVKTLHPKVHGGLLAIRGNDEHAE 91 Query: 187 DMKRQKYEMISVVVCNLYPFVQT 255 MK I ++V NLYPF T Sbjct: 92 AMKTHGIAPIDLLVVNLYPFEAT 114 Score = 58.0 bits (134), Expect = 2e-07 Identities = 29/68 (42%), Positives = 45/68 (66%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRS 511 +KNH+ V VV D DYDAV++++ ++ TTL R+RLA KA+ T+ YD AIS++F + Sbjct: 140 SKNHEDVAVVVDVNDYDAVLEDLARHEG-STTLLLRRRLAAKAYARTAAYDAAISNWFAA 198 Query: 512 NTRPGKPN 535 + P+ Sbjct: 199 TIQNDAPD 206 >UniRef50_Q8ZAR3 Cluster: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)]; n=59; Proteobacteria|Rep: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)] - Yersinia pestis Length = 529 Score = 91.5 bits (217), Expect = 2e-17 Identities = 46/85 (54%), Positives = 58/85 (68%) Frame = +1 Query: 1 SECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSD 180 S+ G++L+++GGTAR L +AGL V +VSD T PEM+ GRVKTLHP VH GIL R D Sbjct: 28 SQRGIELLSTGGTARLLADAGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGR-RGQD 86 Query: 181 QEDMKRQKYEMISVVVCNLYPFVQT 255 M + + I +VV NLYPF QT Sbjct: 87 DGIMAQHGIQPIDIVVVNLYPFAQT 111 Score = 54.4 bits (125), Expect = 3e-06 Identities = 27/64 (42%), Positives = 38/64 (59%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRS 511 AKNH V +V +DY A++ E+ +N T TR LA+KAF HT+ YD I++YF + Sbjct: 138 AKNHKDVAIVVKSSDYPAIITEL-DNNDGSLTYPTRFNLAIKAFEHTAAYDSMIANYFGT 196 Query: 512 NTRP 523 P Sbjct: 197 LVPP 200 Score = 38.7 bits (86), Expect = 0.15 Identities = 16/30 (53%), Positives = 23/30 (76%) Frame = +3 Query: 240 PVRPDVSKPDVTVADAVENIDIGGVTLLRA 329 P V++PD ++ DAVENIDIGG T++R+ Sbjct: 107 PFAQTVARPDCSLEDAVENIDIGGPTMVRS 136 >UniRef50_Q7X311 Cluster: Putative AICAR transformylase; n=1; uncultured Acidobacteria bacterium|Rep: Putative AICAR transformylase - uncultured Acidobacteria bacterium Length = 571 Score = 90.2 bits (214), Expect = 5e-17 Identities = 41/82 (50%), Positives = 60/82 (73%), Gaps = 1/82 (1%) Frame = +1 Query: 13 LQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGIL-ARLSDSDQED 189 ++++++GGTA++LR AG+ V+DVSD+T PEM+ GRVKTLHP +H G+L R S S + Sbjct: 37 IEIVSTGGTAKTLREAGIEVRDVSDVTGFPEMMDGRVKTLHPKIHGGLLGVRDSPSHESS 96 Query: 190 MKRQKYEMISVVVCNLYPFVQT 255 M+ E I +VV +LYPF +T Sbjct: 97 MREHGIEPIDMVVIDLYPFERT 118 Score = 36.3 bits (80), Expect = 0.81 Identities = 19/57 (33%), Positives = 32/57 (56%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDY 502 AKN V V+ + ++Y + +E++ + +L TR+RLA AF T+ YD + Y Sbjct: 145 AKNFHSVAVITNTSEYGPIAEELRAHDC-SLSLHTRRRLAEIAFQRTAQYDSIVFGY 200 Score = 34.7 bits (76), Expect = 2.5 Identities = 28/73 (38%), Positives = 32/73 (43%), Gaps = 3/73 (4%) Frame = +1 Query: 538 TLRYGMNPHQKPAQVFTTRDS--LPITTLNGAP-GFINLCDALNAWQLVKELKEALSLPA 708 +LRYG NPHQ T S L+G F N DA AW LV + E A Sbjct: 274 SLRYGENPHQIAGLYKTAAQSGIANAELLSGKEMSFNNYVDADAAWHLVCDFDEL----A 329 Query: 709 AASFKHVSPAGAA 747 A KH + AG A Sbjct: 330 CAIIKHTNAAGVA 342 >UniRef50_O67775 Cluster: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)]; n=9; Bacteria|Rep: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)] - Aquifex aeolicus Length = 506 Score = 89.4 bits (212), Expect = 8e-17 Identities = 42/82 (51%), Positives = 61/82 (74%), Gaps = 1/82 (1%) Frame = +1 Query: 4 ECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILAR-LSDSD 180 E G +++++GGTA+ LR G++V++VS+IT PE+L GRVKTLHP VH GIL R + D Sbjct: 22 ELGYEIVSTGGTAKYLREKGISVKEVSEITGFPEILEGRVKTLHPVVHGGILFRDWVEKD 81 Query: 181 QEDMKRQKYEMISVVVCNLYPF 246 +E++++ + I VVV NLYPF Sbjct: 82 KEEIEKHGIKPIDVVVVNLYPF 103 Score = 50.8 bits (116), Expect = 4e-05 Identities = 27/59 (45%), Positives = 37/59 (62%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFR 508 AKN RV ++ DP DYD V++++K+ TL R LA KAF+HT+ YD IS F+ Sbjct: 132 AKNFFRVVILVDPEDYDWVIEKLKKG---NLTLQDRAYLAWKAFSHTAYYDGVISQAFK 187 >UniRef50_A7HM64 Cluster: IMP cyclohydrolase; n=1; Fervidobacterium nodosum Rt17-B1|Rep: IMP cyclohydrolase - Fervidobacterium nodosum Rt17-B1 Length = 429 Score = 88.6 bits (210), Expect = 1e-16 Identities = 43/80 (53%), Positives = 59/80 (73%), Gaps = 1/80 (1%) Frame = +1 Query: 10 GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSD-SDQE 186 G+++I++GGTA+ L +AG+ V+ VSD+T PE+LGGRVKTLHP + GILA L D S + Sbjct: 27 GVEIISTGGTAKLLSDAGIPVKQVSDVTGFPEILGGRVKTLHPKIFGGILADLGDKSHVK 86 Query: 187 DMKRQKYEMISVVVCNLYPF 246 D++ E I +VV NLYPF Sbjct: 87 DLRDNFIEPIDLVVVNLYPF 106 Score = 55.2 bits (127), Expect = 2e-06 Identities = 29/54 (53%), Positives = 32/54 (59%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAI 493 AKNH V VVCDPADYD V+K I + L R+ ALKAF HT YD I Sbjct: 135 AKNHRNVVVVCDPADYDKVIKSI--DLCGDVQLHDRRMFALKAFYHTMKYDATI 186 >UniRef50_A7DF55 Cluster: Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; n=3; Alphaproteobacteria|Rep: Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase - Methylobacterium extorquens PA1 Length = 581 Score = 88.2 bits (209), Expect = 2e-16 Identities = 43/86 (50%), Positives = 61/86 (70%), Gaps = 1/86 (1%) Frame = +1 Query: 1 SECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILA-RLSDS 177 S+ G++L+++GGT R+L AGL V++VS++TR PEM+ GRVKTLHPAVH G+LA R + Sbjct: 78 SQRGVELVSTGGTHRALTEAGLAVREVSELTRFPEMMDGRVKTLHPAVHGGLLAVRDNPE 137 Query: 178 DQEDMKRQKYEMISVVVCNLYPFVQT 255 Q + I ++V NLYPF +T Sbjct: 138 HQAALAAHGIGAIDLLVVNLYPFEET 163 Score = 53.6 bits (123), Expect = 5e-06 Identities = 27/57 (47%), Positives = 39/57 (68%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDY 502 AKNH V VV D +DY A++ E+ E+ + T TR+RLA KAF+ T+ YD AI+++ Sbjct: 189 AKNHADVAVVVDVSDYGAILAELAEHDGNLTAT-TRRRLAQKAFSRTASYDAAIANW 244 Score = 33.5 bits (73), Expect = 5.7 Identities = 28/80 (35%), Positives = 34/80 (42%), Gaps = 5/80 (6%) Frame = +1 Query: 523 GQAQLTLRYGMNPHQKPAQVFTTRDSLP-ITTLNGAPG----FINLCDALNAWQLVKELK 687 G +LRYG NPHQ A P I T G + NL D A++ V E Sbjct: 262 GTLAQSLRYGENPHQSAAFYRLPGTLRPGIATARQVQGKELSYNNLNDTDAAYECVAEFD 321 Query: 688 EALSLPAAASFKHVSPAGAA 747 A + A A KH +P G A Sbjct: 322 PART-AAVAIIKHANPCGVA 340 >UniRef50_A0JTW4 Cluster: Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; n=2; Arthrobacter|Rep: Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase - Arthrobacter sp. (strain FB24) Length = 559 Score = 88.2 bits (209), Expect = 2e-16 Identities = 41/85 (48%), Positives = 59/85 (69%), Gaps = 1/85 (1%) Frame = +1 Query: 4 ECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILA-RLSDSD 180 E G++++++G TA+ + AG+ VQ+V ++T +PEML GRVKTLHP VH GILA R + Sbjct: 33 EAGVKIVSTGSTAKKIAAAGIPVQEVEEVTGSPEMLDGRVKTLHPRVHGGILADRRVPAH 92 Query: 181 QEDMKRQKYEMISVVVCNLYPFVQT 255 E + + E +VV NLYPFV+T Sbjct: 93 METLAGMEIEAFDLVVVNLYPFVET 117 Score = 50.4 bits (115), Expect = 5e-05 Identities = 28/60 (46%), Positives = 34/60 (56%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRS 511 AKNH V +V DP Y VV+ E L TRQRLA KAF HT+ YD A++ + S Sbjct: 143 AKNHAAVAIVTDPNFYGDVVRAAAEGGFD---LKTRQRLAAKAFAHTASYDTAVATWTAS 199 >UniRef50_Q1V178 Cluster: Bifunctional purine biosynthesis protein; n=2; Candidatus Pelagibacter ubique|Rep: Bifunctional purine biosynthesis protein - Candidatus Pelagibacter ubique HTCC1002 Length = 518 Score = 86.6 bits (205), Expect = 6e-16 Identities = 38/82 (46%), Positives = 60/82 (73%), Gaps = 1/82 (1%) Frame = +1 Query: 13 LQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSD-SDQED 189 ++LI+SGGT + ++ Q+VS+ T +PE+LGGRVKTLHP +HAGIL++ +D S ++ Sbjct: 36 IELISSGGTFKEIKKLKFKCQEVSEYTGSPEILGGRVKTLHPKIHAGILSKRNDKSHTKE 95 Query: 190 MKRQKYEMISVVVCNLYPFVQT 255 +K +Y+ I +V+ N YPF +T Sbjct: 96 LKANQYDEIDLVIVNFYPFEKT 117 Score = 50.8 bits (116), Expect = 4e-05 Identities = 22/58 (37%), Positives = 40/58 (68%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYF 505 AKN++ VTV+ Y+ ++ E++ NK T++ R++++L+AF+ T+ YD IS+YF Sbjct: 143 AKNYNDVTVITSSDQYETLINELENNKG-STSIEFREKMSLEAFSETAYYDAVISNYF 199 >UniRef50_Q8PYG4 Cluster: Formyltransferase phosphoribosylaminoimidazolecarboxamide; n=4; Methanosarcinaceae|Rep: Formyltransferase phosphoribosylaminoimidazolecarboxamide - Methanosarcina mazei (Methanosarcina frisia) Length = 538 Score = 86.6 bits (205), Expect = 6e-16 Identities = 38/80 (47%), Positives = 57/80 (71%), Gaps = 1/80 (1%) Frame = +1 Query: 10 GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILA-RLSDSDQE 186 G+++I++GGTA+ LR+A + V DVS++T PEM+GGRVKTLHP +H G+L R S E Sbjct: 26 GVKIISTGGTAKILRDADIEVTDVSEVTGYPEMMGGRVKTLHPRIHGGLLCLRESKEQME 85 Query: 187 DMKRQKYEMISVVVCNLYPF 246 + ++ +I ++ NLYPF Sbjct: 86 EAAKEDISLIDLIAVNLYPF 105 Score = 54.8 bits (126), Expect = 2e-06 Identities = 27/57 (47%), Positives = 37/57 (64%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDY 502 AKN+ VTV+ DP+DY ++KE++ + TR LA+KAF HT+DYD AI Y Sbjct: 135 AKNYRSVTVLSDPSDYGRILKELRSSGIISDK--TRAELAVKAFRHTADYDAAIDTY 189 Score = 35.5 bits (78), Expect = 1.4 Identities = 16/30 (53%), Positives = 22/30 (73%) Frame = +3 Query: 240 PVRPDVSKPDVTVADAVENIDIGGVTLLRA 329 P VS+ +V + +A+ENIDIGG TLLR+ Sbjct: 104 PFEITVSRENVELEEAIENIDIGGPTLLRS 133 >UniRef50_UPI00015BCE7E Cluster: UPI00015BCE7E related cluster; n=1; unknown|Rep: UPI00015BCE7E UniRef100 entry - unknown Length = 506 Score = 86.2 bits (204), Expect = 8e-16 Identities = 41/80 (51%), Positives = 56/80 (70%), Gaps = 1/80 (1%) Frame = +1 Query: 10 GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLS-DSDQE 186 G ++++SGGT L+NAG+ +VS++T E+LGGRVKTLHPA+H GIL R + D E Sbjct: 24 GYEILSSGGTYTYLKNAGVDAIEVSEVTGFREILGGRVKTLHPAIHGGILFREDVEKDLE 83 Query: 187 DMKRQKYEMISVVVCNLYPF 246 ++K E I +VV NLYPF Sbjct: 84 EIKENSIEPIDIVVVNLYPF 103 Score = 47.2 bits (107), Expect = 4e-04 Identities = 27/58 (46%), Positives = 35/58 (60%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYF 505 AKNH RV+V+ D DY ++++K N Q R+ LALKAF TS YD I+ YF Sbjct: 132 AKNHKRVSVLTDIEDYGWFIEKLKMNAVSQQD---RKYLALKAFWLTSYYDAVIASYF 186 >UniRef50_A1K9K5 Cluster: Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; n=2; Bacteria|Rep: Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase - Azoarcus sp. (strain BH72) Length = 527 Score = 85.8 bits (203), Expect = 1e-15 Identities = 45/83 (54%), Positives = 56/83 (67%), Gaps = 1/83 (1%) Frame = +1 Query: 10 GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQED 189 G++L+++GGTA LR+AGL V DVS+ T PEML GRVKTLHP VH GILAR ++ D Sbjct: 27 GIKLLSTGGTAALLRDAGLPVTDVSEHTGFPEMLDGRVKTLHPKVHGGILARRDLAEHMD 86 Query: 190 -MKRQKYEMISVVVCNLYPFVQT 255 + I +VV NLYPF T Sbjct: 87 TIAAHDISRIDLVVVNLYPFQAT 109 Score = 50.8 bits (116), Expect = 4e-05 Identities = 29/61 (47%), Positives = 38/61 (62%), Gaps = 4/61 (6%) Frame = +2 Query: 332 AKNHDR----VTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISD 499 AKNH V +V DP DY +V E+K N + + TR LA+KAFTHT+ YD AIS+ Sbjct: 136 AKNHGTEAGGVGIVTDPEDYAGIVAELKANAN-TLSYKTRFALAVKAFTHTARYDSAISN 194 Query: 500 Y 502 + Sbjct: 195 H 195 Score = 44.0 bits (99), Expect = 0.004 Identities = 22/48 (45%), Positives = 30/48 (62%), Gaps = 3/48 (6%) Frame = +3 Query: 240 PVRPDVSKPDVTVADAVENIDIGGVTLLRAQPR---TTTGSPSSVTRP 374 P + V++PD T+ DA+ENIDIGG T++RA + T G VT P Sbjct: 105 PFQATVARPDCTLEDAIENIDIGGPTMVRAAAKNHGTEAGGVGIVTDP 152 Score = 33.5 bits (73), Expect = 5.7 Identities = 26/74 (35%), Positives = 32/74 (43%), Gaps = 5/74 (6%) Frame = +1 Query: 541 LRYGMNPHQKPA---QVFTTRDSL-PITTLNGAP-GFINLCDALNAWQLVKELKEALSLP 705 LRYG NPHQ A + + T L G + N+ DA AW+ VK A Sbjct: 226 LRYGENPHQSAAFYKEPGAAEGGIASYTQLQGKELSYNNIADADAAWECVK----AFDTG 281 Query: 706 AAASFKHVSPAGAA 747 A KH +P G A Sbjct: 282 ACVIVKHANPCGVA 295 >UniRef50_Q9FPL3 Cluster: Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; n=14; Viridiplantae|Rep: Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase - Nicotiana tabacum (Common tobacco) Length = 612 Score = 84.6 bits (200), Expect = 2e-15 Identities = 40/82 (48%), Positives = 56/82 (68%), Gaps = 1/82 (1%) Frame = +1 Query: 4 ECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARL-SDSD 180 E G ++++GGT+ +L AG++V V ++TR PEML GRVKTLHP+VH GILAR + Sbjct: 110 ELGYTIVSTGGTSSALEGAGVSVTKVEELTRFPEMLDGRVKTLHPSVHGGILARRDQEHH 169 Query: 181 QEDMKRQKYEMISVVVCNLYPF 246 E +++ + VVV NLYPF Sbjct: 170 MEALEKHEIGTFDVVVVNLYPF 191 Score = 49.2 bits (112), Expect = 1e-04 Identities = 32/84 (38%), Positives = 46/84 (54%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRS 511 AKNH V VV D DY A+++ ++ + Q R++LA KAF H + YD A+S++ Sbjct: 222 AKNHRDVLVVVDSEDYPALLEFLRGDNDDQQF---RRKLAWKAFQHVASYDSAVSEWLWK 278 Query: 512 NTRPGKPN*P*DTV*THIRSRPRY 583 T G P TV H++S RY Sbjct: 279 QT-VGDKFPPGLTVPLHLKSLLRY 301 >UniRef50_Q83EI4 Cluster: Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; n=5; Coxiella burnetii|Rep: Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase - Coxiella burnetii Length = 526 Score = 84.2 bits (199), Expect = 3e-15 Identities = 41/83 (49%), Positives = 57/83 (68%) Frame = +1 Query: 7 CGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQE 186 CG+++IA+GGTA L+ L V DV T PE++ GRVKTLHP +HAG+LAR D++ Sbjct: 34 CGVEIIATGGTAELLKQHQLPVIDVFTYTGFPEIMDGRVKTLHPKIHAGLLAR-RGIDEK 92 Query: 187 DMKRQKYEMISVVVCNLYPFVQT 255 + + + I ++V NLYPFVQT Sbjct: 93 TLDQHAIKPIDLLVVNLYPFVQT 115 Score = 60.5 bits (140), Expect = 4e-08 Identities = 31/57 (54%), Positives = 37/57 (64%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDY 502 AKN VTVV DP DY +++EIK + H TTL TR+RLA K F H S YD I+ Y Sbjct: 142 AKNFAAVTVVVDPEDYSRILEEIKTH-HGSTTLSTRKRLAQKTFEHLSYYDAHIATY 197 Score = 39.9 bits (89), Expect = 0.065 Identities = 30/77 (38%), Positives = 38/77 (49%), Gaps = 5/77 (6%) Frame = +1 Query: 532 QLTLRYGMNPHQKPAQVFT----TRDSLPITTLNGAP-GFINLCDALNAWQLVKELKEAL 696 ++ LRYG NPHQ A + L G P F NL D+ A++ V E +L Sbjct: 218 KIDLRYGENPHQTAALYSIDPPLSHSLAEAQLLQGKPLSFNNLLDSDCAYRCVYE--GSL 275 Query: 697 SLPAAASFKHVSPAGAA 747 S PA KH +PAGAA Sbjct: 276 SEPACVIVKHATPAGAA 292 >UniRef50_Q0YKD5 Cluster: IMP cyclohydrolase; n=2; Geobacter|Rep: IMP cyclohydrolase - Geobacter sp. FRC-32 Length = 388 Score = 84.2 bits (199), Expect = 3e-15 Identities = 40/72 (55%), Positives = 48/72 (66%) Frame = +1 Query: 532 QLTLRYGMNPHQKPAQVFTTRDSLPITTLNGAPGFINLCDALNAWQLVKELKEALSLPAA 711 ++ L+YG N HQ PA + +S LNG P +IN+ DAL AWQL +ELK A S P A Sbjct: 2 EIKLKYGCNSHQTPANLIIPENS-GFQVLNGTPSYINILDALGAWQLARELKIATSKPGA 60 Query: 712 ASFKHVSPAGAA 747 ASFKH SPAGAA Sbjct: 61 ASFKHTSPAGAA 72 >UniRef50_Q9PC10 Cluster: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)]; n=214; cellular organisms|Rep: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)] - Xylella fastidiosa Length = 527 Score = 84.2 bits (199), Expect = 3e-15 Identities = 40/80 (50%), Positives = 55/80 (68%) Frame = +1 Query: 13 LQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQEDM 192 ++L+++GGTA +R AGL VQDV+D+T PEM+ GRVKTLHP VH G+L R + D M Sbjct: 33 IELLSTGGTATIIREAGLPVQDVADLTGFPEMMDGRVKTLHPMVHGGLLGR-AGIDDAVM 91 Query: 193 KRQKYEMISVVVCNLYPFVQ 252 + I +++ NLYPF Q Sbjct: 92 AKHGIAPIDLLILNLYPFEQ 111 Score = 44.8 bits (101), Expect = 0.002 Identities = 24/60 (40%), Positives = 33/60 (55%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRS 511 AKN RV V P Y ++ E++ + H Q + R LA+ AF H + YD AIS+Y S Sbjct: 139 AKNFARVAVATSPDQYPDLLAELQAH-HGQLSAEKRFALAVAAFNHVAQYDAAISNYLSS 197 Score = 35.5 bits (78), Expect = 1.4 Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 6/87 (6%) Frame = +1 Query: 505 PQQYSPGQAQLT-LRYGMNPHQKPA---QVFTTRDSL-PITTLNGAP-GFINLCDALNAW 666 P Q + ++T LRYG NPHQ A V +L L G + NL DA AW Sbjct: 212 PAQLNNTFVKMTELRYGENPHQTGAFYRDVHPQPGTLATFQQLQGKTLSYNNLVDADAAW 271 Query: 667 QLVKELKEALSLPAAASFKHVSPAGAA 747 + V++ + PA KH +P G A Sbjct: 272 ECVRQFE----APACVIVKHANPCGVA 294 Score = 33.9 bits (74), Expect = 4.3 Identities = 15/30 (50%), Positives = 20/30 (66%) Frame = +3 Query: 240 PVRPDVSKPDVTVADAVENIDIGGVTLLRA 329 P +K D T+ADAV+ IDIGG +LR+ Sbjct: 108 PFEQITAKKDCTLADAVDTIDIGGPAMLRS 137 >UniRef50_P12048 Cluster: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)]; n=71; Bacteria|Rep: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)] - Bacillus subtilis Length = 512 Score = 83.8 bits (198), Expect = 4e-15 Identities = 74/265 (27%), Positives = 122/265 (46%), Gaps = 18/265 (6%) Frame = +1 Query: 1 SECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILA-RLSDS 177 +E G+++I++GGT + L+ G+ V +S++T PE++ GR+KTLHP +H G+LA R ++ Sbjct: 24 TELGVEVISTGGTKKLLQENGVDVIGISEVTGFPEIMDGRLKTLHPNIHGGLLAVRGNEE 83 Query: 178 DQEDMKRQKYEMISVVVCNLYPFVQTYLXXXXXXXXXXXXXXXAA*PSCAHSQEXXXXXX 357 + + I +VV NLYPF +T + P + Sbjct: 84 HMAQINEHGIQPIDLVVVNLYPFKET-ISKEDVTYEEAIENIDIGGPGMLRAASKNHQDV 142 Query: 358 XXXXXXXXCCSQRNQREQTSSDDFGHKAEISPE---GVHSYFGL*PRHIGLLPQQYSPGQ 528 NQ ++ S K E++ + +Y L ++ + + P Q Sbjct: 143 TVIVDPADYSPVLNQIKEEGSVSLQKKRELAAKVFRHTAAYDALIADYLTNVVGEKEPEQ 202 Query: 529 AQLT------LRYGMNPHQKPAQVFTTRDSLPI-------TTLNGAP-GFINLCDALNAW 666 +T LRYG NPHQ+ A + T +LP+ L+G + N+ DA A Sbjct: 203 FTVTFEKKQSLRYGENPHQE-ATFYQT--ALPVKGSIAQAEQLHGKELSYNNIKDADAAV 259 Query: 667 QLVKELKEALSLPAAASFKHVSPAG 741 Q+V+E E PAA + KH++P G Sbjct: 260 QIVREFTE----PAAVAVKHMNPCG 280 Score = 56.8 bits (131), Expect = 5e-07 Identities = 27/57 (47%), Positives = 36/57 (63%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDY 502 +KNH VTV+ DPADY V+ +IKE +L ++ LA K F HT+ YD I+DY Sbjct: 136 SKNHQDVTVIVDPADYSPVLNQIKE--EGSVSLQKKRELAAKVFRHTAAYDALIADY 190 Score = 39.1 bits (87), Expect = 0.11 Identities = 17/30 (56%), Positives = 22/30 (73%) Frame = +3 Query: 240 PVRPDVSKPDVTVADAVENIDIGGVTLLRA 329 P + +SK DVT +A+ENIDIGG +LRA Sbjct: 105 PFKETISKEDVTYEEAIENIDIGGPGMLRA 134 >UniRef50_A2SS05 Cluster: Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; n=3; Methanomicrobiales|Rep: Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase - Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z) Length = 497 Score = 83.4 bits (197), Expect = 5e-15 Identities = 39/76 (51%), Positives = 53/76 (69%) Frame = +1 Query: 19 LIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQEDMKR 198 +++SGGTA++LR AG+ +DVS+ T+ PEM+ GRVKTLHP VH G+L R D + MK Sbjct: 28 ILSSGGTAKALREAGIPAKDVSEYTQFPEMMDGRVKTLHPKVHGGLLGR-RGIDDDVMKA 86 Query: 199 QKYEMISVVVCNLYPF 246 E I ++ NLYPF Sbjct: 87 HFIEPIDILCVNLYPF 102 Score = 46.4 bits (105), Expect = 8e-04 Identities = 25/57 (43%), Positives = 34/57 (59%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDY 502 +KN+ V V+ DP+DY ++ IK T + RLA KAFT T+ YD AIS+Y Sbjct: 131 SKNYKDVAVLTDPSDYPMAIEAIKTGGF---TSEQKLRLATKAFTRTAAYDAAISNY 184 >UniRef50_P67543 Cluster: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)]; n=18; Staphylococcus|Rep: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)] - Staphylococcus aureus (strain Mu50 / ATCC 700699) Length = 492 Score = 83.4 bits (197), Expect = 5e-15 Identities = 41/86 (47%), Positives = 56/86 (65%), Gaps = 1/86 (1%) Frame = +1 Query: 1 SECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILA-RLSDS 177 ++ +L ++GGT R L A + V+ VSD+T PE++ GRVKTLHPAVH GILA R Sbjct: 22 TQLNYELYSTGGTKRILDEANVPVRSVSDLTHFPEIMDGRVKTLHPAVHGGILADRNKPQ 81 Query: 178 DQEDMKRQKYEMISVVVCNLYPFVQT 255 ++ Q ++I +VV NLYPF QT Sbjct: 82 HLNELSEQHIDLIDMVVVNLYPFQQT 107 Score = 46.4 bits (105), Expect = 8e-04 Identities = 22/61 (36%), Positives = 36/61 (59%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRS 511 AKN+ VT + PADY V+ ++ + ++ RQ L +K F HT++YD AI +F+ Sbjct: 134 AKNYKHVTTIVHPADYHEVLTRLRNDSLDESY---RQSLMIKVFEHTAEYDEAIVRFFKG 190 Query: 512 N 514 + Sbjct: 191 D 191 Score = 42.3 bits (95), Expect = 0.012 Identities = 18/30 (60%), Positives = 24/30 (80%) Frame = +3 Query: 240 PVRPDVSKPDVTVADAVENIDIGGVTLLRA 329 P + V+ PDVT+ +A+ENIDIGG T+LRA Sbjct: 103 PFQQTVANPDVTMDEAIENIDIGGPTMLRA 132 >UniRef50_Q8CXK7 Cluster: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)]; n=34; Bacteria|Rep: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)] - Oceanobacillus iheyensis Length = 510 Score = 81.8 bits (193), Expect = 2e-14 Identities = 37/85 (43%), Positives = 54/85 (63%), Gaps = 1/85 (1%) Frame = +1 Query: 4 ECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQ 183 E G +++++GGT RS+ AG+ V V ++T PEML GRVKTLHP +H G+L + S+ + Sbjct: 24 ESGFEILSTGGTLRSIAEAGIDVTPVDEVTGFPEMLDGRVKTLHPMIHGGLLGKRSNHEH 83 Query: 184 -EDMKRQKYEMISVVVCNLYPFVQT 255 M+ I +V NLYPF +T Sbjct: 84 LSQMEEHGIRSIDLVAVNLYPFKET 108 Score = 49.6 bits (113), Expect = 8e-05 Identities = 28/67 (41%), Positives = 35/67 (52%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRS 511 AKN + V VV P DY+ V+ I T RQ+LA K F HT+ YD I++YF S Sbjct: 135 AKNFEDVLVVTGPTDYNRVLAAITSETD---TYEFRQQLAAKVFRHTASYDAMIANYFLS 191 Query: 512 NTRPGKP 532 T P Sbjct: 192 QTEEQYP 198 Score = 38.3 bits (85), Expect = 0.20 Identities = 16/30 (53%), Positives = 22/30 (73%) Frame = +3 Query: 240 PVRPDVSKPDVTVADAVENIDIGGVTLLRA 329 P + V KPDV+ D +ENIDIGG ++LR+ Sbjct: 104 PFKETVQKPDVSHQDIIENIDIGGPSMLRS 133 >UniRef50_Q95QQ5 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 420 Score = 81.4 bits (192), Expect = 2e-14 Identities = 35/49 (71%), Positives = 41/49 (83%) Frame = +1 Query: 601 LPITTLNGAPGFINLCDALNAWQLVKELKEALSLPAAASFKHVSPAGAA 747 +PI LNG+PG+IN+ D LN WQLVKEL +A +PAAASFKHVSPAGAA Sbjct: 1 MPIKVLNGSPGYINILDGLNGWQLVKELSDATKMPAAASFKHVSPAGAA 49 >UniRef50_P43852 Cluster: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)]; n=88; Bacteria|Rep: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)] - Haemophilus influenzae Length = 532 Score = 81.4 bits (192), Expect = 2e-14 Identities = 42/82 (51%), Positives = 54/82 (65%) Frame = +1 Query: 10 GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQED 189 G++L+++GGTA+ L L V +VSD T PEM+ GRVKTLHP VH GIL R +D Sbjct: 30 GVKLLSTGGTAKLLAQNALPVIEVSDYTGFPEMMDGRVKTLHPKVHGGILGR-RGTDDAI 88 Query: 190 MKRQKYEMISVVVCNLYPFVQT 255 M++ E I +VV NLYPF T Sbjct: 89 MQQHGIEGIDMVVVNLYPFAAT 110 Score = 52.8 bits (121), Expect = 9e-06 Identities = 25/64 (39%), Positives = 41/64 (64%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRS 511 AKNH V +V + D++A++ E+ ++++ T TR LA+KAF HT+ YD I++YF Sbjct: 137 AKNHKDVAIVVNNHDFNAILAEMDQHQN-SLTFETRFDLAIKAFEHTAQYDSMIANYFGQ 195 Query: 512 NTRP 523 +P Sbjct: 196 LVKP 199 Score = 43.6 bits (98), Expect = 0.005 Identities = 19/30 (63%), Positives = 24/30 (80%) Frame = +3 Query: 240 PVRPDVSKPDVTVADAVENIDIGGVTLLRA 329 P V+KPD T+ADAVENIDIGG T++R+ Sbjct: 106 PFAATVAKPDCTLADAVENIDIGGPTMVRS 135 >UniRef50_A6G003 Cluster: Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; n=1; Plesiocystis pacifica SIR-1|Rep: Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase - Plesiocystis pacifica SIR-1 Length = 543 Score = 80.6 bits (190), Expect = 4e-14 Identities = 36/81 (44%), Positives = 56/81 (69%) Frame = +1 Query: 13 LQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQEDM 192 ++++++GGT R+L G+ V VS+ T APE+L GRVKTLHP +H GILA +++ Q ++ Sbjct: 39 VEVLSTGGTYRALSELGVAVVKVSEFTGAPEILDGRVKTLHPKIHGGILALPTEAHQREL 98 Query: 193 KRQKYEMISVVVCNLYPFVQT 255 + I +V+ NLYPF +T Sbjct: 99 ELHDIAPIDLVIVNLYPFRET 119 Score = 46.4 bits (105), Expect = 8e-04 Identities = 24/66 (36%), Positives = 37/66 (56%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRS 511 AKN +RV V+ DP DY ++ + + E + R+ +A KAF HT+ YD AI+ Y Sbjct: 146 AKNWNRVAVIVDPEDYSSLSEVLGETEGTLPE-SFRRNMARKAFAHTAAYDAAIASYLAR 204 Query: 512 NTRPGK 529 + G+ Sbjct: 205 HDDAGE 210 Score = 46.0 bits (104), Expect = 0.001 Identities = 36/94 (38%), Positives = 49/94 (52%), Gaps = 10/94 (10%) Frame = +1 Query: 496 GLLPQQ-YSPGQAQLTLRYGMNPHQKPAQVFTTRDSLPITTLNGAP-------GFINLCD 651 G +P+ + G++ LRYG NPHQ+ T+ S T L+ A + NL D Sbjct: 215 GTIPEGLFVSGESVAELRYGENPHQQARFFATSYASDEATGLDQAIVHQGKALSYNNLLD 274 Query: 652 ALNAWQLVKELKEALSL--PAAASFKHVSPAGAA 747 A A L+++LK L AAA FKH+SP GAA Sbjct: 275 ADAALGLIRDLKAGLPEGGKAAAVFKHLSPCGAA 308 Score = 41.1 bits (92), Expect = 0.028 Identities = 17/30 (56%), Positives = 23/30 (76%) Frame = +3 Query: 240 PVRPDVSKPDVTVADAVENIDIGGVTLLRA 329 P R ++KP + ADA+ENIDIGG T++RA Sbjct: 115 PFRETIAKPGCSFADAIENIDIGGPTMVRA 144 >UniRef50_Q9F1T4 Cluster: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)]; n=57; Bacteria|Rep: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)] - Streptococcus suis Length = 515 Score = 79.8 bits (188), Expect = 7e-14 Identities = 39/85 (45%), Positives = 55/85 (64%), Gaps = 1/85 (1%) Frame = +1 Query: 10 GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLS-DSDQE 186 G ++I++GGT +L AG+T + D+T PEM+ GRVKTLHP +H G+LAR DS + Sbjct: 26 GWEIISTGGTKVALDQAGVTTIAIDDVTGFPEMMDGRVKTLHPKIHGGLLARRDLDSHLQ 85 Query: 187 DMKRQKYEMISVVVCNLYPFVQTYL 261 + +I +VV NLYPF +T L Sbjct: 86 AANDHEIGLIDLVVVNLYPFKETIL 110 Score = 70.1 bits (164), Expect = 5e-11 Identities = 36/67 (53%), Positives = 41/67 (61%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRS 511 AKNH VTVV DPADY V+ EI E +T+ TRQRLA K F HT+ YD I+DYF Sbjct: 135 AKNHASVTVVVDPADYPTVLGEIAEQG--ETSYATRQRLAAKVFRHTAAYDALIADYFTK 192 Query: 512 NTRPGKP 532 KP Sbjct: 193 QVGEDKP 199 Score = 36.3 bits (80), Expect = 0.81 Identities = 16/30 (53%), Positives = 22/30 (73%) Frame = +3 Query: 240 PVRPDVSKPDVTVADAVENIDIGGVTLLRA 329 P + + +PDVT AVENIDIGG ++LR+ Sbjct: 104 PFKETILRPDVTYDLAVENIDIGGPSMLRS 133 >UniRef50_A7BET6 Cluster: Putative uncharacterized protein; n=1; Actinomyces odontolyticus ATCC 17982|Rep: Putative uncharacterized protein - Actinomyces odontolyticus ATCC 17982 Length = 614 Score = 79.4 bits (187), Expect = 9e-14 Identities = 37/85 (43%), Positives = 56/85 (65%), Gaps = 1/85 (1%) Frame = +1 Query: 4 ECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILA-RLSDSD 180 E G++++++G TA + AG+ V V D+T PE+L GRVKTLHP +H+GILA + + Sbjct: 38 EAGVEIVSTGSTAARIAAAGVAVTPVDDVTGFPEVLEGRVKTLHPFIHSGILADQRKAAH 97 Query: 181 QEDMKRQKYEMISVVVCNLYPFVQT 255 +E + + + +VVCNLYPF T Sbjct: 98 REQIAQLGIQAFDLVVCNLYPFQDT 122 Score = 41.1 bits (92), Expect = 0.028 Identities = 24/57 (42%), Positives = 31/57 (54%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDY 502 AKNH V VV P Y V + + TL R+ LA +AF HT+ YDLAI+ + Sbjct: 148 AKNHPSVAVVTSPERYADVAEAVAGEGF---TLEQRRVLAAEAFAHTATYDLAIAGW 201 >UniRef50_Q8XMK2 Cluster: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)]; n=14; Bacteria|Rep: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)] - Clostridium perfringens Length = 501 Score = 78.6 bits (185), Expect = 2e-13 Identities = 38/81 (46%), Positives = 56/81 (69%), Gaps = 1/81 (1%) Frame = +1 Query: 13 LQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILA-RLSDSDQED 189 +++I+SGGT + L+ + V+++S+IT PEML GRVKTLHP VHAGILA R + + Sbjct: 27 VEIISSGGTYKYLKENNIEVKEISEITDFPEMLDGRVKTLHPLVHAGILAIRDNKEHMKT 86 Query: 190 MKRQKYEMISVVVCNLYPFVQ 252 ++ ++ I VV NLYPF + Sbjct: 87 LEEREINTIDYVVVNLYPFFE 107 Score = 42.7 bits (96), Expect = 0.009 Identities = 25/57 (43%), Positives = 33/57 (57%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDY 502 AKN V V+ D DY+ V+ EIKEN + + R+ LA K F S YD AIS++ Sbjct: 134 AKNFKDVVVLSDKKDYEKVMNEIKEN--NCVSFKLRKTLAGKVFNLMSAYDAAISNF 188 Score = 35.5 bits (78), Expect = 1.4 Identities = 26/73 (35%), Positives = 36/73 (49%), Gaps = 4/73 (5%) Frame = +1 Query: 541 LRYGMNPHQKPAQVFTTRDSLPITT---LNG-APGFINLCDALNAWQLVKELKEALSLPA 708 LRYG NPHQ A +T + + LNG A + N+ D AW++ E +E A Sbjct: 210 LRYGENPHQGAAYYSSTEFDGAMNSFEILNGKALSYNNIKDLDIAWKVACEFEET----A 265 Query: 709 AASFKHVSPAGAA 747 + KH +P G A Sbjct: 266 CCALKHNTPCGVA 278 >UniRef50_Q8F3W6 Cluster: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)]; n=6; Bacteria|Rep: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)] - Leptospira interrogans Length = 511 Score = 77.8 bits (183), Expect = 3e-13 Identities = 36/83 (43%), Positives = 57/83 (68%), Gaps = 1/83 (1%) Frame = +1 Query: 10 GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSD-SDQE 186 G+++I++GGT + L++ G+ + D T PE+L GRVKTLHP VH G+L +S+ + ++ Sbjct: 28 GVEIISTGGTLKLLKDNGIAAIAIDDYTGFPEILDGRVKTLHPKVHGGLLGVISNPAHKQ 87 Query: 187 DMKRQKYEMISVVVCNLYPFVQT 255 M+ K I +VV NLYPF++T Sbjct: 88 KMEELKIPKIDLVVVNLYPFLKT 110 Score = 37.9 bits (84), Expect = 0.26 Identities = 21/58 (36%), Positives = 30/58 (51%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYF 505 AKN+ V+ DP DY + I + + + R KAF+HT+ YD AIS +F Sbjct: 137 AKNYKHTLVLTDPNDYKKIQNLISSSGISEEISASYMR---KAFSHTAMYDAAISSWF 191 Score = 37.1 bits (82), Expect = 0.46 Identities = 15/30 (50%), Positives = 23/30 (76%) Frame = +3 Query: 240 PVRPDVSKPDVTVADAVENIDIGGVTLLRA 329 P VSKP+V + +A+ENIDIGG +++R+ Sbjct: 106 PFLKTVSKPEVQLEEAIENIDIGGPSMIRS 135 >UniRef50_Q9PNY2 Cluster: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)]; n=21; Epsilonproteobacteria|Rep: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)] - Campylobacter jejuni Length = 510 Score = 77.8 bits (183), Expect = 3e-13 Identities = 36/83 (43%), Positives = 55/83 (66%), Gaps = 1/83 (1%) Frame = +1 Query: 10 GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQ-E 186 G +++++GGT + L+ G+ V +VSD T++PE+ GRVKTLHP +H GIL + SD + + Sbjct: 24 GFEILSTGGTFKLLKENGIKVIEVSDFTKSPELFEGRVKTLHPKIHGGILHKRSDENHIK 83 Query: 187 DMKRQKYEMISVVVCNLYPFVQT 255 K + I +V NLYPF +T Sbjct: 84 QAKENEILGIDLVCVNLYPFKKT 106 Score = 51.2 bits (117), Expect = 3e-05 Identities = 23/65 (35%), Positives = 39/65 (60%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRS 511 AKN+ V V+CDP DY+ V++ +K+ ++ + R L +KA+ HT++YD I++Y Sbjct: 132 AKNYKDVMVLCDPLDYEKVIETLKKGQNDE---NFRLNLMIKAYEHTANYDAYIANYMNE 188 Query: 512 NTRPG 526 G Sbjct: 189 RFNGG 193 Score = 40.3 bits (90), Expect = 0.049 Identities = 30/85 (35%), Positives = 35/85 (41%), Gaps = 1/85 (1%) Frame = +1 Query: 496 GLLPQQYSPGQAQLTLRYGMNPHQKPA-QVFTTRDSLPITTLNGAPGFINLCDALNAWQL 672 G ++ GQ +YG NPHQK A F S L G F NL D A L Sbjct: 193 GFGASKFIVGQKVFDTKYGENPHQKGALYEFDAFFSANFKALKGEASFNNLTDINAALNL 252 Query: 673 VKELKEALSLPAAASFKHVSPAGAA 747 +A PA A KH +P G A Sbjct: 253 ASSFDKA---PAIAIVKHGNPCGFA 274 >UniRef50_Q8G6B1 Cluster: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)]; n=89; Bacteria|Rep: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)] - Bifidobacterium longum Length = 545 Score = 77.8 bits (183), Expect = 3e-13 Identities = 36/85 (42%), Positives = 56/85 (65%), Gaps = 1/85 (1%) Frame = +1 Query: 4 ECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQ 183 + G +++++G TA+ L G+ V +VSD+T PE L GRVKTLHP +HAGILA +++ + Sbjct: 30 KAGTEVVSTGSTAKKLAELGVKVTEVSDVTGFPECLDGRVKTLHPYIHAGILADMTNPEH 89 Query: 184 -EDMKRQKYEMISVVVCNLYPFVQT 255 + ++ + +VV NLYPF T Sbjct: 90 AKQLEEFGIKPFDLVVVNLYPFADT 114 Score = 48.0 bits (109), Expect = 2e-04 Identities = 24/57 (42%), Positives = 33/57 (57%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDY 502 AKNH V +V DPADY V + + +L R+ LA KAF HT+ YD I+++ Sbjct: 140 AKNHATVAIVTDPADYALVASRVADGTGF--SLDERKWLAAKAFAHTAAYDATINEW 194 Score = 34.7 bits (76), Expect = 2.5 Identities = 26/74 (35%), Positives = 34/74 (45%), Gaps = 4/74 (5%) Frame = +1 Query: 538 TLRYGMNPHQKPAQVFTTRDSLPIT---TLNGAP-GFINLCDALNAWQLVKELKEALSLP 705 TLRYG N HQ+ A + L G P + N DA AW+ V ++ A+ Sbjct: 237 TLRYGENSHQQAALYIDPLNQTGFAHAEQLGGKPMSYNNYVDADAAWRTVWDMAPAI--- 293 Query: 706 AAASFKHVSPAGAA 747 A A KH +P G A Sbjct: 294 AVAVVKHNNPCGLA 307 >UniRef50_Q6L122 Cluster: Phosphoribosylaminoimidazolecarboxamide formyltransferase; n=4; Thermoplasmatales|Rep: Phosphoribosylaminoimidazolecarboxamide formyltransferase - Picrophilus torridus Length = 494 Score = 76.6 bits (180), Expect = 6e-13 Identities = 35/79 (44%), Positives = 54/79 (68%) Frame = +1 Query: 25 ASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQEDMKRQK 204 A+ GT + L ++G+ + +SDIT ++L GRVKTLHPAV +GIL+R + + D+KR Sbjct: 26 ATPGTFKFLSDSGIKAKRISDITGFDDLLNGRVKTLHPAVFSGILSRRDEQSEADLKRYN 85 Query: 205 YEMISVVVCNLYPFVQTYL 261 Y +V+CNLY F ++Y+ Sbjct: 86 YFDFDIVICNLYNF-ESYI 103 Score = 47.2 bits (107), Expect = 4e-04 Identities = 21/54 (38%), Positives = 35/54 (64%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAI 493 AKN+ VTV P DY+ ++K++++ + +L TR+ LAL+AF + YD+ I Sbjct: 126 AKNYQHVTVASSPEDYNIIIKDLRDG---EISLRTRETLALRAFARAAYYDMII 176 >UniRef50_Q7MUT5 Cluster: Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; n=24; Bacteria|Rep: Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase - Porphyromonas gingivalis (Bacteroides gingivalis) Length = 508 Score = 74.1 bits (174), Expect = 3e-12 Identities = 35/83 (42%), Positives = 52/83 (62%), Gaps = 1/83 (1%) Frame = +1 Query: 10 GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLS-DSDQE 186 G++ +++GGT + + G + V D+TR P MLGGRVKTLHP + GILAR +SD Sbjct: 32 GVEFVSTGGTHEFITSLGYACRAVDDLTRYPSMLGGRVKTLHPMIFGGILARRGHESDVR 91 Query: 187 DMKRQKYEMISVVVCNLYPFVQT 255 ++ +I +V+ +LYPF T Sbjct: 92 EVGEYGLPLIDLVIVDLYPFEAT 114 >UniRef50_Q7VRP9 Cluster: Phosphoribosylaminoimidazolecarboxamide formyltransferase, IMP cyclohydrolase and MGS-like domain; n=2; Candidatus Blochmannia|Rep: Phosphoribosylaminoimidazolecarboxamide formyltransferase, IMP cyclohydrolase and MGS-like domain - Blochmannia floridanus Length = 549 Score = 73.3 bits (172), Expect = 6e-12 Identities = 36/82 (43%), Positives = 54/82 (65%) Frame = +1 Query: 1 SECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSD 180 S G++L+++ GTA L NAGLTV +SD T PE++ G+VKTLH + AGIL+R + D Sbjct: 28 SHLGIKLLSTEGTALILTNAGLTVNKISDYTNFPEIMNGQVKTLHHKICAGILSR-KNLD 86 Query: 181 QEDMKRQKYEMISVVVCNLYPF 246 + + + + I +V+ N YPF Sbjct: 87 ESIIHKYGIQPIDMVIVNFYPF 108 Score = 55.2 bits (127), Expect = 2e-06 Identities = 32/88 (36%), Positives = 44/88 (50%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRS 511 AKN+ ++ D DYD ++ EI H +L TR LA KAF + YD ISDYF+ Sbjct: 138 AKNYKNTVIIVDNNDYDNILNEIN-TLHGSISLNTRLNLAAKAFKYIKQYDTMISDYFQH 196 Query: 512 NTRPGKPN*P*DTV*THIRSRPRYSRPE 595 + +PN P T+ I+ PE Sbjct: 197 QLKL-QPNKPHHTIQKRIQPFNHSQLPE 223 >UniRef50_Q316G8 Cluster: Phosphoribosylaminoimidazolecarboxamide formyltransferase; n=4; Desulfovibrionaceae|Rep: Phosphoribosylaminoimidazolecarboxamide formyltransferase - Desulfovibrio desulfuricans (strain G20) Length = 252 Score = 72.5 bits (170), Expect = 1e-11 Identities = 35/80 (43%), Positives = 50/80 (62%), Gaps = 1/80 (1%) Frame = +1 Query: 10 GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQ-E 186 G++L+++GGT R+L AGL V VS +T PE++GGRVKTLHP +H GILA + + Sbjct: 83 GVELVSTGGTQRTLTEAGLDVTPVSKVTGFPEIMGGRVKTLHPHIHGGILADKDNPEHLA 142 Query: 187 DMKRQKYEMISVVVCNLYPF 246 +K ++ NLY F Sbjct: 143 TLKELGIRTFDLICVNLYNF 162 Score = 53.6 bits (123), Expect = 5e-06 Identities = 28/63 (44%), Positives = 39/63 (61%) Frame = +2 Query: 329 TAKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFR 508 TAKN + V+ DPADY A ++E+++N + L RQ +A+K F TS YD I+DY Sbjct: 190 TAKNFHSMLVLPDPADYQAAMQEMRDN-DMRVGLAMRQAMAVKTFRATSAYDGMIADYLG 248 Query: 509 SNT 517 S T Sbjct: 249 SKT 251 >UniRef50_Q8A155 Cluster: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)]; n=5; Bacteroides|Rep: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)] - Bacteroides thetaiotaomicron Length = 507 Score = 72.5 bits (170), Expect = 1e-11 Identities = 36/86 (41%), Positives = 56/86 (65%), Gaps = 2/86 (2%) Frame = +1 Query: 4 ECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQ 183 E G++ +++GGT + + + G + V D+T P +LGGRVKTLHP + GIL R D +Q Sbjct: 29 EEGVEFLSTGGTRQFIESLGYPCKAVEDLTTYPSILGGRVKTLHPKIFGGILCR-RDLEQ 87 Query: 184 EDMKRQKYEM--ISVVVCNLYPFVQT 255 + + +KYE+ I +V+ +LYPF T Sbjct: 88 DIQQIEKYEIPEIDLVIVDLYPFEAT 113 Score = 35.1 bits (77), Expect = 1.9 Identities = 20/58 (34%), Positives = 34/58 (58%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYF 505 AKN++ V +V A Y ++ + E+ ++L R+ +A +AF +S YD AI +YF Sbjct: 139 AKNYNDVIIVASQAQYKPLLDMLMEHGA-TSSLEERRWMAKEAFAVSSHYDSAIFNYF 195 >UniRef50_A7I7L2 Cluster: Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; n=1; Candidatus Methanoregula boonei 6A8|Rep: Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase - Methanoregula boonei (strain 6A8) Length = 525 Score = 69.7 bits (163), Expect = 7e-11 Identities = 35/76 (46%), Positives = 46/76 (60%) Frame = +1 Query: 19 LIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQEDMKR 198 +++SGGT +L AG+ +VS T PEM+ GRVKTLHP VH G+L R D M + Sbjct: 58 IMSSGGTGTALAGAGIPFTEVSRYTGFPEMMDGRVKTLHPKVHGGLLGR-RQIDDAIMAK 116 Query: 199 QKYEMISVVVCNLYPF 246 I ++V NLYPF Sbjct: 117 YGINRIGLLVVNLYPF 132 Score = 43.2 bits (97), Expect = 0.007 Identities = 30/68 (44%), Positives = 36/68 (52%), Gaps = 4/68 (5%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRL--ALKAFTHTSDYDLAISDYF 505 AKN V VV DP+DY VVK + N QRL A KAF T+ YD AIS++ Sbjct: 161 AKNFKDVAVVVDPSDYPEVVKTLSSN----VGFSHEQRLIFAKKAFARTAAYDAAISNHL 216 Query: 506 RS--NTRP 523 + NT P Sbjct: 217 SNLDNTFP 224 >UniRef50_Q83GZ1 Cluster: Phosphoribosylaminoimidazolecarboxamide formyltransferase; n=2; Tropheryma whipplei|Rep: Phosphoribosylaminoimidazolecarboxamide formyltransferase - Tropheryma whipplei (strain Twist) (Whipple's bacillus) Length = 542 Score = 68.9 bits (161), Expect = 1e-10 Identities = 32/81 (39%), Positives = 52/81 (64%), Gaps = 1/81 (1%) Frame = +1 Query: 13 LQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILA-RLSDSDQED 189 ++++++G TA +R + V+DVS++T E+L GRVKTLHP +HA ILA S + Sbjct: 32 VKIVSTGSTAEFIRGVSIPVRDVSEVTGVGELLDGRVKTLHPKIHAPILADTTSQMHRAQ 91 Query: 190 MKRQKYEMISVVVCNLYPFVQ 252 +++ + +VV NLYPF + Sbjct: 92 LQQLGVDAFDLVVVNLYPFFE 112 Score = 52.0 bits (119), Expect = 2e-05 Identities = 25/55 (45%), Positives = 36/55 (65%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAIS 496 AKNH RV V+ DP+DY V+ ++ + R +LA+KA++HTS+YDL IS Sbjct: 140 AKNHTRVVVIVDPSDYIHVINSLERGAPSRL----RHQLAIKAYSHTSEYDLHIS 190 >UniRef50_A1G3C3 Cluster: Phosphoribosylaminoimidazolecarboxamide formyltransferase; n=1; Salinispora arenicola CNS205|Rep: Phosphoribosylaminoimidazolecarboxamide formyltransferase - Salinispora arenicola CNS205 Length = 190 Score = 67.3 bits (157), Expect = 4e-10 Identities = 33/77 (42%), Positives = 49/77 (63%) Frame = +1 Query: 10 GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQED 189 G ++A+ GT R LR+ G+TV VSD+ P +LGGRVKTL ++ GILAR +D+ + Sbjct: 24 GWDVVATEGTRRLLRDHGVTVGAVSDLAGVPTLLGGRVKTLTVSLMGGILARDEPADRAE 83 Query: 190 MKRQKYEMISVVVCNLY 240 ++R + +V CN Y Sbjct: 84 VERHGLTRVHLVCCNYY 100 >UniRef50_A7PK27 Cluster: Chromosome chr15 scaffold_19, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr15 scaffold_19, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 227 Score = 60.5 bits (140), Expect = 4e-08 Identities = 31/80 (38%), Positives = 43/80 (53%), Gaps = 1/80 (1%) Frame = +1 Query: 10 GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDS-DQE 186 G ++++ GGT +L NA ++ V +T P++L G VKTLHP + GIL R E Sbjct: 45 GYRIVSFGGTTLALENAWVSTTKVEQLTCFPKILDGHVKTLHPNIQGGILPRRDQKHHME 104 Query: 187 DMKRQKYEMISVVVCNLYPF 246 + VVV NLYPF Sbjct: 105 ALNEHGIGTFDVVVVNLYPF 124 >UniRef50_Q8D244 Cluster: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)]; n=2; Gammaproteobacteria|Rep: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)] - Wigglesworthia glossinidia brevipalpis Length = 529 Score = 60.5 bits (140), Expect = 4e-08 Identities = 29/78 (37%), Positives = 46/78 (58%) Frame = +1 Query: 13 LQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQEDM 192 ++LI + GT + L G+ VS+ PE++ GRVKTLHP +H GIL+ ++ + + Sbjct: 33 VKLITTSGTYKYLLEKGIFSTSVSEYINHPEIINGRVKTLHPKIHGGILS--NNKNINEN 90 Query: 193 KRQKYEMISVVVCNLYPF 246 K + I +V+ N YPF Sbjct: 91 KNLNIKKIDMVITNFYPF 108 >UniRef50_Q89B23 Cluster: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)]; n=2; Buchnera aphidicola (Baizongia pistaciae)|Rep: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)] - Buchnera aphidicola subsp. Baizongia pistaciae Length = 529 Score = 60.5 bits (140), Expect = 4e-08 Identities = 27/78 (34%), Positives = 49/78 (62%) Frame = +1 Query: 13 LQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQEDM 192 ++L A+ GTA L+ + D+++ T PE++ GR+KTLH ++A ILA+ D++ + Sbjct: 32 IKLFATKGTANFLKKNNIYATDITNYTNFPEIMNGRIKTLHHKIYASILAQ-PKHDKKTI 90 Query: 193 KRQKYEMISVVVCNLYPF 246 ++ ++ +VV N YPF Sbjct: 91 EKYNIILMDIVVINFYPF 108 Score = 36.7 bits (81), Expect = 0.61 Identities = 21/63 (33%), Positives = 31/63 (49%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRS 511 AKN+ V VV P Y ++V E+ N + + T+ + A AF HT +YD I Y Sbjct: 138 AKNYKNVLVVTQPNLYQSIVNEMNLNNNIISET-TKLKFATIAFKHTMNYDNNIYQYLSK 196 Query: 512 NTR 520 + Sbjct: 197 KNK 199 >UniRef50_A1IEQ8 Cluster: IMP cyclohydrolase; n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep: IMP cyclohydrolase - Candidatus Desulfococcus oleovorans Hxd3 Length = 225 Score = 59.3 bits (137), Expect = 1e-07 Identities = 31/63 (49%), Positives = 40/63 (63%) Frame = +2 Query: 329 TAKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFR 508 +AKN RV V DPADY+ V E+ E++ +L TR LA KAF HT+ YD AI+DY + Sbjct: 154 SAKNFLRVASVVDPADYNTVADEM-EHRQGALSLDTRFELAQKAFDHTAAYDRAIADYLK 212 Query: 509 SNT 517 T Sbjct: 213 KQT 215 Score = 52.4 bits (120), Expect = 1e-05 Identities = 33/87 (37%), Positives = 46/87 (52%), Gaps = 6/87 (6%) Frame = +1 Query: 13 LQLIASGGTARSLRN-----AGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARL-SD 174 + + ++GGT + + A + VSD T PE GG VKTL ++ G+L ++ Sbjct: 42 VHIFSTGGTYQKIYEIFGSAAKSVLTQVSDYTGQPETQGGLVKTLDFKIYLGLLTETYNE 101 Query: 175 SDQEDMKRQKYEMISVVVCNLYPFVQT 255 S DMKR I +VV NLYPF QT Sbjct: 102 SHARDMKRTGAVAIDMVVVNLYPFSQT 128 >UniRef50_Q6MIZ2 Cluster: IMP cyclohydrolase; n=1; Bdellovibrio bacteriovorus|Rep: IMP cyclohydrolase - Bdellovibrio bacteriovorus Length = 507 Score = 56.8 bits (131), Expect = 5e-07 Identities = 33/82 (40%), Positives = 46/82 (56%), Gaps = 1/82 (1%) Frame = +1 Query: 13 LQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSD-SDQED 189 ++LIASGGTA++L AGL V V ++ E GR+KT+ + + +L R D +D Sbjct: 29 VELIASGGTAKALTEAGLKVTAVETLSGKGEAFNGRMKTISFEIASSLLFRRQDENDVRQ 88 Query: 190 MKRQKYEMISVVVCNLYPFVQT 255 E I +VV NLYPF T Sbjct: 89 AAELGIEPIDLVVVNLYPFHAT 110 Score = 50.4 bits (115), Expect = 5e-05 Identities = 25/62 (40%), Positives = 36/62 (58%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRS 511 AKN VTV+CDP+ Y +KE N + TT RQ+ A +T T+ YD+AI+ + Sbjct: 136 AKNFHSVTVLCDPSQYSEFLKEFNGN-NGSTTWEFRQKCAAAVYTMTAFYDMAIAGFLTQ 194 Query: 512 NT 517 N+ Sbjct: 195 NS 196 >UniRef50_A4MAE3 Cluster: Phosphoribosylaminoimidazolecarboxamide formyltransferase; n=1; Petrotoga mobilis SJ95|Rep: Phosphoribosylaminoimidazolecarboxamide formyltransferase - Petrotoga mobilis SJ95 Length = 489 Score = 55.2 bits (127), Expect = 2e-06 Identities = 29/80 (36%), Positives = 47/80 (58%), Gaps = 1/80 (1%) Frame = +1 Query: 10 GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSD-SDQE 186 G+++I + GT + L+ G+ ++D PE+LGGRVK++ P + GILA+ +D +E Sbjct: 27 GVEIICTEGTNKYLQEKGIPTVKMADYIGFPEILGGRVKSIDPKLAGGILAKSNDKKHEE 86 Query: 187 DMKRQKYEMISVVVCNLYPF 246 DM + I +VV N F Sbjct: 87 DMINYNIKRIDMVVGNFPTF 106 Score = 41.5 bits (93), Expect = 0.021 Identities = 22/58 (37%), Positives = 31/58 (53%) Frame = +2 Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYF 505 AKN+ V + DP DY V+ +++ L R++LALK F TS YD +I F Sbjct: 135 AKNYKDVVALADPKDYQTVIDNLEDCG--DVPLQLRRKLALKVFFSTSKYDASIHKIF 190 >UniRef50_Q9X0X6 Cluster: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)]; n=4; Thermotogaceae|Rep: Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)] - Thermotoga maritima Length = 452 Score = 55.2 bits (127), Expect = 2e-06 Identities = 27/52 (51%), Positives = 35/52 (67%) Frame = +1 Query: 4 ECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGIL 159 E G ++ AS GTA+ L++ G+ DVS IT +LGG VKTLHP + AGIL Sbjct: 23 EKGWEIWASSGTAKFLKSNGIEANDVSTITGFENLLGGLVKTLHPEIFAGIL 74 Score = 41.5 bits (93), Expect = 0.021 Identities = 29/71 (40%), Positives = 35/71 (49%) Frame = +1 Query: 535 LTLRYGMNPHQKPAQVFTTRDSLPITTLNGAPGFINLCDALNAWQLVKELKEALSLPAAA 714 L LRYG NPH+K A V+ + + I F N+ DA NAW + K L A Sbjct: 167 LQLRYGENPHEK-AFVY-GKPAFEILHEGKTISFNNILDAENAWFMAKNLPRM----GAV 220 Query: 715 SFKHVSPAGAA 747 KH SP GAA Sbjct: 221 VVKHQSPCGAA 231 >UniRef50_A5B1A5 Cluster: DNA-directed RNA polymerase; n=1; Vitis vinifera|Rep: DNA-directed RNA polymerase - Vitis vinifera (Grape) Length = 202 Score = 50.0 bits (114), Expect = 6e-05 Identities = 22/52 (42%), Positives = 33/52 (63%) Frame = +1 Query: 10 GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILAR 165 G ++++ GGT +L NA ++ V +T P++L G VKTLHP + GIL R Sbjct: 45 GYRIVSFGGTTLALENAWVSTTKVEQLTCFPKILDGHVKTLHPNIQGGILPR 96 >UniRef50_A5B3D8 Cluster: DNA-directed RNA polymerase; n=1; Vitis vinifera|Rep: DNA-directed RNA polymerase - Vitis vinifera (Grape) Length = 153 Score = 46.4 bits (105), Expect = 8e-04 Identities = 24/48 (50%), Positives = 26/48 (54%), Gaps = 1/48 (2%) Frame = +1 Query: 106 MLGGRVKTLHPAVHAGILARLSDS-DQEDMKRQKYEMISVVVCNLYPF 246 ML G VKTLHP +H GILAR E + VVV NLYPF Sbjct: 1 MLDGHVKTLHPNIHGGILARRDQKHHMEALNEHGIGTFDVVVVNLYPF 48 >UniRef50_A6PRZ4 Cluster: Phosphoribosylaminoimidazolecarboxamide formyltransferase; n=1; Victivallis vadensis ATCC BAA-548|Rep: Phosphoribosylaminoimidazolecarboxamide formyltransferase - Victivallis vadensis ATCC BAA-548 Length = 372 Score = 40.3 bits (90), Expect = 0.049 Identities = 35/98 (35%), Positives = 44/98 (44%), Gaps = 11/98 (11%) Frame = +1 Query: 487 RHIGLLPQQYSPGQAQLT----LRYGMNPHQ-----KPAQVFTTRDSLPITTLNGAPGF- 636 +H+G P + + G + LRYG NPHQ KPA + I NG G Sbjct: 13 KHVGDFPAEITIGSRRYVKVDDLRYGTNPHQAASYYKPADEACVIGDMKILK-NGKSGLS 71 Query: 637 -INLCDALNAWQLVKELKEALSLPAAASFKHVSPAGAA 747 NL D A +VK PA A KHV+P+GAA Sbjct: 72 QTNLEDISYALNIVK----FFDTPACAVMKHVNPSGAA 105 >UniRef50_A6DLC7 Cluster: IMP cyclohydrolase; n=1; Lentisphaera araneosa HTCC2155|Rep: IMP cyclohydrolase - Lentisphaera araneosa HTCC2155 Length = 369 Score = 37.9 bits (84), Expect = 0.26 Identities = 31/76 (40%), Positives = 37/76 (48%), Gaps = 7/76 (9%) Frame = +1 Query: 541 LRYGMNPHQ-----KPAQVFTTRDSLPITTLNGAPGF--INLCDALNAWQLVKELKEALS 699 LRYG NPHQ KPA + + L + NG G NL D A +VK E Sbjct: 36 LRYGTNPHQTAAFYKPAGLESPIGDLKVLK-NGKSGLSQTNLEDISYALNIVKFFDE--- 91 Query: 700 LPAAASFKHVSPAGAA 747 P A KHV+P+GAA Sbjct: 92 -PTCAVMKHVNPSGAA 106 >UniRef50_Q0W4V4 Cluster: Predicted ABC-type transport system, permease component; n=2; uncultured methanogenic archaeon RC-I|Rep: Predicted ABC-type transport system, permease component - Uncultured methanogenic archaeon RC-I Length = 408 Score = 36.7 bits (81), Expect = 0.61 Identities = 28/83 (33%), Positives = 37/83 (44%), Gaps = 1/83 (1%) Frame = +1 Query: 457 GVHSYFG-L*PRHIGLLPQQYSPGQAQLTLRYGMNPHQKPAQVFTTRDSLPITTLNGAPG 633 GV + FG L I LLPQ + + YG+ KP FT RD I T+ PG Sbjct: 48 GVSAEFGDLDLNQIILLPQSLEDQSGGMGMSYGIAQTSKPPARFTDRD---IQTILSTPG 104 Query: 634 FINLCDALNAWQLVKELKEALSL 702 + + + A+ V L E SL Sbjct: 105 VVEVNPKIEAYGTVSYLSENRSL 127 >UniRef50_A1FWI7 Cluster: Putative uncharacterized protein precursor; n=1; Stenotrophomonas maltophilia R551-3|Rep: Putative uncharacterized protein precursor - Stenotrophomonas maltophilia R551-3 Length = 589 Score = 35.5 bits (78), Expect = 1.4 Identities = 18/50 (36%), Positives = 26/50 (52%) Frame = -3 Query: 150 SMYRWM*SFHPTSEHLRCSRDVRHILNCEAGVPKRPGGTATGNQLQATFR 1 +M+ + P H R + DV H+L+ +A + R GG A G QL A R Sbjct: 480 AMHHRVQGLDPAVHHFREAGDVGHVLHGQARIADRLGGAAGGQQLHAACR 529 >UniRef50_Q08W60 Cluster: Putative uncharacterized protein; n=1; Stigmatella aurantiaca DW4/3-1|Rep: Putative uncharacterized protein - Stigmatella aurantiaca DW4/3-1 Length = 611 Score = 35.1 bits (77), Expect = 1.9 Identities = 20/66 (30%), Positives = 31/66 (46%) Frame = +3 Query: 183 GRHETSEVRDDKRGGL*PVPVRPDVSKPDVTVADAVENIDIGGVTLLRAQPRTTTGSPSS 362 G ETSE+R++ G P R ++ VE + +GG L+A P TT + ++ Sbjct: 239 GHSETSELREESHDGGNIPPSRQPTRLLELAGGQLVEAVHMGGRRSLQAAPTATTATTTT 298 Query: 363 VTRPTT 380 T T Sbjct: 299 TTTTAT 304 >UniRef50_Q9HS43 Cluster: Phosphoribosylaminoimidazole-succinocarboxamide formyltransferase; n=5; Halobacteriaceae|Rep: Phosphoribosylaminoimidazole-succinocarboxamide formyltransferase - Halobacterium salinarium (Halobacterium halobium) Length = 595 Score = 35.1 bits (77), Expect = 1.9 Identities = 29/76 (38%), Positives = 34/76 (44%), Gaps = 7/76 (9%) Frame = +1 Query: 541 LRYGMNPHQKPA----QVFTTRDSLPITTLNG---APGFINLCDALNAWQLVKELKEALS 699 LRYG NPHQ A + LN A + N DA A LV+E + Sbjct: 287 LRYGENPHQDAAVYRDNTHAAASVVHADQLNPDAKALSYNNYNDADAALALVREFDDG-- 344 Query: 700 LPAAASFKHVSPAGAA 747 PAAA KH +PAG A Sbjct: 345 -PAAAVIKHTNPAGCA 359 >UniRef50_Q4P5L9 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 567 Score = 34.3 bits (75), Expect = 3.3 Identities = 17/36 (47%), Positives = 24/36 (66%), Gaps = 1/36 (2%) Frame = -1 Query: 701 RLSASFSSLTSCQAFSASHRLIN-PGAPFSVVIGKL 597 RL F S++S +AFS SHR +N P +PF+V + L Sbjct: 43 RLLPGFRSVSSARAFSTSHRRLNTPKSPFAVFVETL 78 >UniRef50_Q6AGB7 Cluster: Flagellar hook-associated protein 3; n=1; Leifsonia xyli subsp. xyli|Rep: Flagellar hook-associated protein 3 - Leifsonia xyli subsp. xyli Length = 290 Score = 33.9 bits (74), Expect = 4.3 Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 1/59 (1%) Frame = +2 Query: 353 TVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAIS-DYFRSNTRPG 526 T PA+ D++VK I++ K + L Q L F TSD D A + N PG Sbjct: 102 TGTSSPANQDSIVKSIEQLKQNLLALANTQYLGRSVFAGTSDADTAFDVKSYAFNGTPG 160 >UniRef50_Q337Q0 Cluster: Expressed protein; n=1; Oryza sativa (japonica cultivar-group)|Rep: Expressed protein - Oryza sativa subsp. japonica (Rice) Length = 170 Score = 33.5 bits (73), Expect = 5.7 Identities = 21/56 (37%), Positives = 29/56 (51%), Gaps = 1/56 (1%) Frame = -2 Query: 382 IVVGRVTD-DGDPVVVLGCARRRVTPPMSMFSTASATVTSGLDTSGRTGTGYRPPR 218 + VG+ D DGDPV+ LG AR+ M + + V G D + G+G R PR Sbjct: 20 VAVGQTVDLDGDPVLALGMARQVAVEHMLVEAEEQEVVERGHDMA---GSGIRYPR 72 >UniRef50_Q54WL3 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 276 Score = 33.5 bits (73), Expect = 5.7 Identities = 13/66 (19%), Positives = 33/66 (50%) Frame = +2 Query: 338 NHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRSNT 517 N++ +++ CD + +++E+K+ + T + + ++ ++Y+L I D F +N Sbjct: 46 NNNNISINCDNTQFQTILRELKKREFQNKTRKPINKKLNSSNSNNNNYNLKIEDNFINNN 105 Query: 518 RPGKPN 535 N Sbjct: 106 NNNNKN 111 >UniRef50_Q4T8W0 Cluster: Chromosome undetermined SCAF7713, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF7713, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1076 Score = 33.1 bits (72), Expect = 7.5 Identities = 16/42 (38%), Positives = 20/42 (47%) Frame = +3 Query: 474 RTMTSPYRTTSAAILARASPTDLKIRYEPTSEAGPGIHDQRQ 599 R P R SA ++ A P + R P + GPG DQRQ Sbjct: 583 RWRPGPAREASATSVSSAGPAGMDQRQVPGGDRGPGCEDQRQ 624 >UniRef50_Q0ICG1 Cluster: Lipase/esterase family protein; n=1; Synechococcus sp. CC9311|Rep: Lipase/esterase family protein - Synechococcus sp. (strain CC9311) Length = 290 Score = 33.1 bits (72), Expect = 7.5 Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 2/77 (2%) Frame = -2 Query: 580 PGPASDVG-SYRILRSVGLARASIAAEVVRYGEVIVRSMSERLQG*SLPCAQSRLMMFVL 404 P P D +YR L + G +IA + G +V + R Q SLP L+M + Sbjct: 89 PAPLDDAEEAYRWLLAQGYRSEAIAVAGISAGATLVTQLLHRCQSKSLPMPSLALVMAGV 148 Query: 403 FDF-FDYSIVVGRVTDD 356 DF + VV +DD Sbjct: 149 MDFSYGRESVVFNASDD 165 >UniRef50_Q8LNV5 Cluster: Putative uncharacterized protein OSJNBa0012L23.53; n=2; Oryza sativa|Rep: Putative uncharacterized protein OSJNBa0012L23.53 - Oryza sativa subsp. japonica (Rice) Length = 262 Score = 33.1 bits (72), Expect = 7.5 Identities = 16/48 (33%), Positives = 25/48 (52%) Frame = +3 Query: 30 WRYRQVASERRPHSSRCVGHHESTGDARRSGENFTSSGTCWDLSSIIR 173 WRY+ VA R +S C G + + GE + +G C D++ I+R Sbjct: 121 WRYKGVA---RQSASMCCGQLDHSSGMHDDGEVWLRAGPCSDIAGIVR 165 >UniRef50_Q5FJY6 Cluster: Carbamoyl-phosphate synthase large subunit; n=5; Lactobacillus|Rep: Carbamoyl-phosphate synthase large subunit - Lactobacillus acidophilus Length = 1061 Score = 32.7 bits (71), Expect = 9.9 Identities = 20/63 (31%), Positives = 30/63 (47%) Frame = +1 Query: 10 GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQED 189 G +L+A+ GTA AG+T V + P L +++ H V + LSD+ ED Sbjct: 964 GFKLVATEGTANIFAEAGITTGIVEKVHNNPRNLLEKIRQ-HKIVMVVNITNLSDAASED 1022 Query: 190 MKR 198 R Sbjct: 1023 ALR 1025 >UniRef50_Q0SCZ3 Cluster: Fructuronate reductase; n=1; Rhodococcus sp. RHA1|Rep: Fructuronate reductase - Rhodococcus sp. (strain RHA1) Length = 511 Score = 32.7 bits (71), Expect = 9.9 Identities = 19/50 (38%), Positives = 29/50 (58%), Gaps = 1/50 (2%) Frame = +2 Query: 374 DYDAVVKEIKENKHHQTTLGTRQR-LALKAFTHTSDYDLAISDYFRSNTR 520 D DAV ++++E + +TT+G R LAL+A TH + + D SN R Sbjct: 142 DSDAVRRDLREVRTPRTTIGQIARGLALRASTHAAPVTILSCDNLLSNGR 191 >UniRef50_A3X0C9 Cluster: Putative uncharacterized protein; n=1; Nitrobacter sp. Nb-311A|Rep: Putative uncharacterized protein - Nitrobacter sp. Nb-311A Length = 242 Score = 32.7 bits (71), Expect = 9.9 Identities = 17/54 (31%), Positives = 26/54 (48%) Frame = +3 Query: 543 KIRYEPTSEAGPGIHDQRQLADHDTERCAWIYQPVRRAERLAARQGAEGSAEPP 704 K++ P EA PG D+ +AD + R + R R+ A +G + A PP Sbjct: 60 KVKQTPLPEAKPGAPDRITIADGEFGRESANLAAARERARIQASEGDDNEAAPP 113 >UniRef50_Q9AXF7 Cluster: RNA stability factor MCA1; n=1; Chlamydomonas reinhardtii|Rep: RNA stability factor MCA1 - Chlamydomonas reinhardtii Length = 1068 Score = 32.7 bits (71), Expect = 9.9 Identities = 28/100 (28%), Positives = 40/100 (40%), Gaps = 3/100 (3%) Frame = +1 Query: 388 SQRNQREQTSSDDFGHKAEISPEGVHSYF---GL*PRHIGLLPQQYSPGQAQLTLRYGMN 558 S RN R Q S +G + P VH+ + G L QQ S + + R + Sbjct: 150 SGRNGRPQGPSGRYGSSSASGPAPVHASYNNSGAPSSSPNALQQQQSQSGSADSRRCDLG 209 Query: 559 PHQKPAQVFTTRDSLPITTLNGAPGFINLCDALNAWQLVK 678 PAQ+ RD +L G + C L+ W+L K Sbjct: 210 DTGLPAQLLALRDPACPVSLPPPTGLPSSCLPLDNWKLDK 249 >UniRef50_Q5C3G2 Cluster: SJCHGC02321 protein; n=1; Schistosoma japonicum|Rep: SJCHGC02321 protein - Schistosoma japonicum (Blood fluke) Length = 286 Score = 32.7 bits (71), Expect = 9.9 Identities = 14/26 (53%), Positives = 18/26 (69%) Frame = -2 Query: 406 LFDFFDYSIVVGRVTDDGDPVVVLGC 329 L DF YS+++GR T DGD V V+ C Sbjct: 204 LGDFVFYSLLIGRATLDGDAVTVVTC 229 >UniRef50_Q6CDD1 Cluster: Similarities with DEHA0F12342g Debaryomyces hansenii; n=1; Yarrowia lipolytica|Rep: Similarities with DEHA0F12342g Debaryomyces hansenii - Yarrowia lipolytica (Candida lipolytica) Length = 872 Score = 32.7 bits (71), Expect = 9.9 Identities = 25/76 (32%), Positives = 34/76 (44%) Frame = +3 Query: 135 SSGTCWDLSSIIRL*PGRHETSEVRDDKRGGL*PVPVRPDVSKPDVTVADAVENIDIGGV 314 SSGT + SS+ GR+ S VR GG + V ++ A A+ + GG+ Sbjct: 639 SSGTSFGYSSMTEFSFGRYGNSPVRGGGTGGSNALSA---VGSAALSTAAALSPVRNGGL 695 Query: 315 TLLRAQPRTTTGSPSS 362 TL P TT P S Sbjct: 696 TLAPLTPATTLAPPVS 711 >UniRef50_Q6C2W2 Cluster: Similarity; n=1; Yarrowia lipolytica|Rep: Similarity - Yarrowia lipolytica (Candida lipolytica) Length = 337 Score = 32.7 bits (71), Expect = 9.9 Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 1/44 (2%) Frame = -2 Query: 235 GYRPPRLSSRTSDVSCLPGQS-RIIELRSQHVPLDVKFSPDLRA 107 GY ++ + CL G S I + + PLDV F+PDLR+ Sbjct: 217 GYISAAVNVANGQIFCLLGHSLAICDFAGNYTPLDVHFNPDLRS 260 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 744,042,977 Number of Sequences: 1657284 Number of extensions: 15277128 Number of successful extensions: 54112 Number of sequences better than 10.0: 73 Number of HSP's better than 10.0 without gapping: 51139 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 54016 length of database: 575,637,011 effective HSP length: 99 effective length of database: 411,565,895 effective search space used: 61734884250 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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