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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= NV021283
         (749 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_P31939 Cluster: Bifunctional purine biosynthesis protei...   141   1e-32
UniRef50_Q4SHT8 Cluster: Chromosome 5 SCAF14581, whole genome sh...   121   2e-26
UniRef50_Q73LG8 Cluster: Phosphoribosylaminoimidazolecarboxamide...    97   3e-19
UniRef50_Q550I9 Cluster: AICAR transformylase / IMP cyclohydrola...    96   7e-19
UniRef50_P74741 Cluster: Bifunctional purine biosynthesis protei...    96   7e-19
UniRef50_Q9RW01 Cluster: Bifunctional purine biosynthesis protei...    93   5e-18
UniRef50_Q2JR47 Cluster: Bifunctional purine biosynthesis protei...    93   7e-18
UniRef50_Q2JI00 Cluster: Bifunctional purine biosynthesis protei...    93   9e-18
UniRef50_A5E8X1 Cluster: Phosphoribosylaminoimidazolecarboxamide...    92   2e-17
UniRef50_Q8ZAR3 Cluster: Bifunctional purine biosynthesis protei...    91   2e-17
UniRef50_Q7X311 Cluster: Putative AICAR transformylase; n=1; unc...    90   5e-17
UniRef50_O67775 Cluster: Bifunctional purine biosynthesis protei...    89   8e-17
UniRef50_A7HM64 Cluster: IMP cyclohydrolase; n=1; Fervidobacteri...    89   1e-16
UniRef50_A7DF55 Cluster: Phosphoribosylaminoimidazolecarboxamide...    88   2e-16
UniRef50_A0JTW4 Cluster: Phosphoribosylaminoimidazolecarboxamide...    88   2e-16
UniRef50_Q1V178 Cluster: Bifunctional purine biosynthesis protei...    87   6e-16
UniRef50_Q8PYG4 Cluster: Formyltransferase phosphoribosylaminoim...    87   6e-16
UniRef50_UPI00015BCE7E Cluster: UPI00015BCE7E related cluster; n...    86   8e-16
UniRef50_A1K9K5 Cluster: Phosphoribosylaminoimidazolecarboxamide...    86   1e-15
UniRef50_Q9FPL3 Cluster: Phosphoribosylaminoimidazolecarboxamide...    85   2e-15
UniRef50_Q83EI4 Cluster: Phosphoribosylaminoimidazolecarboxamide...    84   3e-15
UniRef50_Q0YKD5 Cluster: IMP cyclohydrolase; n=2; Geobacter|Rep:...    84   3e-15
UniRef50_Q9PC10 Cluster: Bifunctional purine biosynthesis protei...    84   3e-15
UniRef50_P12048 Cluster: Bifunctional purine biosynthesis protei...    84   4e-15
UniRef50_A2SS05 Cluster: Phosphoribosylaminoimidazolecarboxamide...    83   5e-15
UniRef50_P67543 Cluster: Bifunctional purine biosynthesis protei...    83   5e-15
UniRef50_Q8CXK7 Cluster: Bifunctional purine biosynthesis protei...    82   2e-14
UniRef50_Q95QQ5 Cluster: Putative uncharacterized protein; n=2; ...    81   2e-14
UniRef50_P43852 Cluster: Bifunctional purine biosynthesis protei...    81   2e-14
UniRef50_A6G003 Cluster: Bifunctional phosphoribosylaminoimidazo...    81   4e-14
UniRef50_Q9F1T4 Cluster: Bifunctional purine biosynthesis protei...    80   7e-14
UniRef50_A7BET6 Cluster: Putative uncharacterized protein; n=1; ...    79   9e-14
UniRef50_Q8XMK2 Cluster: Bifunctional purine biosynthesis protei...    79   2e-13
UniRef50_Q8F3W6 Cluster: Bifunctional purine biosynthesis protei...    78   3e-13
UniRef50_Q9PNY2 Cluster: Bifunctional purine biosynthesis protei...    78   3e-13
UniRef50_Q8G6B1 Cluster: Bifunctional purine biosynthesis protei...    78   3e-13
UniRef50_Q6L122 Cluster: Phosphoribosylaminoimidazolecarboxamide...    77   6e-13
UniRef50_Q7MUT5 Cluster: Phosphoribosylaminoimidazolecarboxamide...    74   3e-12
UniRef50_Q7VRP9 Cluster: Phosphoribosylaminoimidazolecarboxamide...    73   6e-12
UniRef50_Q316G8 Cluster: Phosphoribosylaminoimidazolecarboxamide...    73   1e-11
UniRef50_Q8A155 Cluster: Bifunctional purine biosynthesis protei...    73   1e-11
UniRef50_A7I7L2 Cluster: Phosphoribosylaminoimidazolecarboxamide...    70   7e-11
UniRef50_Q83GZ1 Cluster: Phosphoribosylaminoimidazolecarboxamide...    69   1e-10
UniRef50_A1G3C3 Cluster: Phosphoribosylaminoimidazolecarboxamide...    67   4e-10
UniRef50_A7PK27 Cluster: Chromosome chr15 scaffold_19, whole gen...    60   4e-08
UniRef50_Q8D244 Cluster: Bifunctional purine biosynthesis protei...    60   4e-08
UniRef50_Q89B23 Cluster: Bifunctional purine biosynthesis protei...    60   4e-08
UniRef50_A1IEQ8 Cluster: IMP cyclohydrolase; n=1; Candidatus Des...    59   1e-07
UniRef50_Q6MIZ2 Cluster: IMP cyclohydrolase; n=1; Bdellovibrio b...    57   5e-07
UniRef50_A4MAE3 Cluster: Phosphoribosylaminoimidazolecarboxamide...    55   2e-06
UniRef50_Q9X0X6 Cluster: Bifunctional purine biosynthesis protei...    55   2e-06
UniRef50_A5B1A5 Cluster: DNA-directed RNA polymerase; n=1; Vitis...    50   6e-05
UniRef50_A5B3D8 Cluster: DNA-directed RNA polymerase; n=1; Vitis...    46   8e-04
UniRef50_A6PRZ4 Cluster: Phosphoribosylaminoimidazolecarboxamide...    40   0.049
UniRef50_A6DLC7 Cluster: IMP cyclohydrolase; n=1; Lentisphaera a...    38   0.26 
UniRef50_Q0W4V4 Cluster: Predicted ABC-type transport system, pe...    37   0.61 
UniRef50_A1FWI7 Cluster: Putative uncharacterized protein precur...    36   1.4  
UniRef50_Q08W60 Cluster: Putative uncharacterized protein; n=1; ...    35   1.9  
UniRef50_Q9HS43 Cluster: Phosphoribosylaminoimidazole-succinocar...    35   1.9  
UniRef50_Q4P5L9 Cluster: Putative uncharacterized protein; n=1; ...    34   3.3  
UniRef50_Q6AGB7 Cluster: Flagellar hook-associated protein 3; n=...    34   4.3  
UniRef50_Q337Q0 Cluster: Expressed protein; n=1; Oryza sativa (j...    33   5.7  
UniRef50_Q54WL3 Cluster: Putative uncharacterized protein; n=1; ...    33   5.7  
UniRef50_Q4T8W0 Cluster: Chromosome undetermined SCAF7713, whole...    33   7.5  
UniRef50_Q0ICG1 Cluster: Lipase/esterase family protein; n=1; Sy...    33   7.5  
UniRef50_Q8LNV5 Cluster: Putative uncharacterized protein OSJNBa...    33   7.5  
UniRef50_Q5FJY6 Cluster: Carbamoyl-phosphate synthase large subu...    33   9.9  
UniRef50_Q0SCZ3 Cluster: Fructuronate reductase; n=1; Rhodococcu...    33   9.9  
UniRef50_A3X0C9 Cluster: Putative uncharacterized protein; n=1; ...    33   9.9  
UniRef50_Q9AXF7 Cluster: RNA stability factor MCA1; n=1; Chlamyd...    33   9.9  
UniRef50_Q5C3G2 Cluster: SJCHGC02321 protein; n=1; Schistosoma j...    33   9.9  
UniRef50_Q6CDD1 Cluster: Similarities with DEHA0F12342g Debaryom...    33   9.9  
UniRef50_Q6C2W2 Cluster: Similarity; n=1; Yarrowia lipolytica|Re...    33   9.9  

>UniRef50_P31939 Cluster: Bifunctional purine biosynthesis protein
           PURH [Includes: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3)
           (5-aminoimidazole-4-carboxamide ribonucleotide
           formyltransferase) (AICAR transformylase); IMP
           cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]; n=105; cellular organisms|Rep:
           Bifunctional purine biosynthesis protein PURH [Includes:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3)
           (5-aminoimidazole-4-carboxamide ribonucleotide
           formyltransferase) (AICAR transformylase); IMP
           cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)] - Homo sapiens (Human)
          Length = 592

 Score =  141 bits (342), Expect = 1e-32
 Identities = 64/80 (80%), Positives = 71/80 (88%)
 Frame = +1

Query: 508 QQYSPGQAQLTLRYGMNPHQKPAQVFTTRDSLPITTLNGAPGFINLCDALNAWQLVKELK 687
           +QYS G +Q+ LRYGMNPHQ PAQ++T +  LPIT LNGAPGFINLCDALNAWQLVKELK
Sbjct: 195 KQYSKGVSQMPLRYGMNPHQTPAQLYTLQPKLPITVLNGAPGFINLCDALNAWQLVKELK 254

Query: 688 EALSLPAAASFKHVSPAGAA 747
           EAL +PAAASFKHVSPAGAA
Sbjct: 255 EALGIPAAASFKHVSPAGAA 274



 Score =  119 bits (287), Expect = 7e-26
 Identities = 56/82 (68%), Positives = 66/82 (80%)
 Frame = +1

Query: 10  GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQED 189
           GL L+ASGGTA++LR+AGL V+DVS++T  PEMLGGRVKTLHPAVHAGILAR    D  D
Sbjct: 28  GLNLVASGGTAKALRDAGLAVRDVSELTGFPEMLGGRVKTLHPAVHAGILARNIPEDNAD 87

Query: 190 MKRQKYEMISVVVCNLYPFVQT 255
           M R  + +I VV CNLYPFV+T
Sbjct: 88  MARLDFNLIRVVACNLYPFVKT 109



 Score = 81.4 bits (192), Expect = 2e-14
 Identities = 38/65 (58%), Positives = 47/65 (72%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRS 511
           AKNH RVTVVC+P DY  V  E++ ++   T+L TR++LALKAFTHT+ YD AISDYFR 
Sbjct: 136 AKNHARVTVVCEPEDYVVVSTEMQSSESKDTSLETRRQLALKAFTHTAQYDEAISDYFRK 195

Query: 512 NTRPG 526
               G
Sbjct: 196 QYSKG 200



 Score = 43.6 bits (98), Expect = 0.005
 Identities = 28/67 (41%), Positives = 36/67 (53%), Gaps = 5/67 (7%)
 Frame = +3

Query: 240 PVRPDVSKPDVTVADAVENIDIGGVTLLRAQPR-----TTTGSPSSVTRPTTML*SKKSK 404
           P    V+ P VTV +AVE IDIGGVTLLRA  +     T    P      +T + S +SK
Sbjct: 105 PFVKTVASPGVTVEEAVEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVVVSTEMQSSESK 164

Query: 405 RTNIIRR 425
            T++  R
Sbjct: 165 DTSLETR 171


>UniRef50_Q4SHT8 Cluster: Chromosome 5 SCAF14581, whole genome
           shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 5
           SCAF14581, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 628

 Score =  121 bits (291), Expect = 2e-26
 Identities = 56/84 (66%), Positives = 69/84 (82%)
 Frame = +1

Query: 4   ECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQ 183
           + GL L+ASGGTA++LR+AG  V+DVS++T  PEMLGGRVKTLHPAVH GILAR S +D 
Sbjct: 20  DVGLSLVASGGTAKTLRDAGWAVRDVSELTGHPEMLGGRVKTLHPAVHGGILARKSPADT 79

Query: 184 EDMKRQKYEMISVVVCNLYPFVQT 255
            DM++  Y +I VVVCNLYPFV+T
Sbjct: 80  ADMEKLGYSLIRVVVCNLYPFVKT 103



 Score =  113 bits (272), Expect = 4e-24
 Identities = 49/67 (73%), Positives = 58/67 (86%)
 Frame = +1

Query: 547 YGMNPHQKPAQVFTTRDSLPITTLNGAPGFINLCDALNAWQLVKELKEALSLPAAASFKH 726
           YGMNPHQ PAQ++T R +LP+  +NG+PGFINLCDALNAWQLV+EL +AL + AA SFKH
Sbjct: 191 YGMNPHQAPAQLYTLRPALPLRVVNGSPGFINLCDALNAWQLVRELSKALGVAAATSFKH 250

Query: 727 VSPAGAA 747
           VSPAGAA
Sbjct: 251 VSPAGAA 257



 Score = 46.4 bits (105), Expect = 8e-04
 Identities = 41/102 (40%), Positives = 49/102 (48%), Gaps = 1/102 (0%)
 Frame = +3

Query: 240 PVRPDVSKPDVTVADAVENIDIGGVTLLRAQPRTTTGSPSSVTRPTTML*SKKSKRTNII 419
           P    VS P VTV DAVE IDIGGVTLLRA       +  +  R T +     +    + 
Sbjct: 99  PFVKTVSNPSVTVEDAVEQIDIGGVTLLRA-------AAKNHARVTVV--CDPADYPRVA 149

Query: 420 RRLWAQG-RD*P*RRSLILRTMTSPYRTTSAAILARASPTDL 542
             +   G RD P R  L   + T PYRTTS    A A P+ L
Sbjct: 150 EEMEGSGSRDTPSRTRL---STTRPYRTTSGDSSAVAFPSCL 188



 Score = 43.6 bits (98), Expect = 0.005
 Identities = 20/36 (55%), Positives = 24/36 (66%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTR 439
           AKNH RVTVVCDPADY  V +E++ +    T   TR
Sbjct: 130 AKNHARVTVVCDPADYPRVAEEMEGSGSRDTPSRTR 165


>UniRef50_Q73LG8 Cluster: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase/IMP cyclohydrolase; n=2; Bacteria|Rep:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase/IMP cyclohydrolase - Treponema
           denticola
          Length = 533

 Score = 97.5 bits (232), Expect = 3e-19
 Identities = 43/82 (52%), Positives = 61/82 (74%)
 Frame = +1

Query: 10  GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQED 189
           G   IASGGTA++L+ AG+ V++VS+ T +PE+LGGRVKTLHP +H GILAR +  D+ +
Sbjct: 25  GYDFIASGGTAKTLQEAGIKVKEVSEYTSSPEILGGRVKTLHPMIHGGILARDTKEDRAE 84

Query: 190 MKRQKYEMISVVVCNLYPFVQT 255
           +K   +  I +V+ NLYPF +T
Sbjct: 85  LKALGFSGIDIVIANLYPFEKT 106



 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 31/63 (49%), Positives = 42/63 (66%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRS 511
           AKN+ RVTV+CDPADYD V  EI+  K  + +L  R+RLA+KAF   + YD AI+ +   
Sbjct: 133 AKNYSRVTVICDPADYDEVSSEIE--KTGEISLSLRKRLAIKAFDLCTRYDAAITSWLSG 190

Query: 512 NTR 520
            +R
Sbjct: 191 LSR 193



 Score = 41.5 bits (93), Expect = 0.021
 Identities = 18/30 (60%), Positives = 21/30 (70%)
 Frame = +3

Query: 240 PVRPDVSKPDVTVADAVENIDIGGVTLLRA 329
           P    +S PD T +D +ENIDIGGV LLRA
Sbjct: 102 PFEKTISSPDSTESDCIENIDIGGVALLRA 131



 Score = 39.9 bits (89), Expect = 0.065
 Identities = 32/80 (40%), Positives = 41/80 (51%), Gaps = 4/80 (5%)
 Frame = +1

Query: 520 PGQAQLTLRYGMNPHQKPAQVFTTRDSL-PI--TTLNG-APGFINLCDALNAWQLVKELK 687
           PGQ    LRYG NPHQK A ++T      P+    L G A  + N+ DA  AW+ V    
Sbjct: 210 PGQ---DLRYGENPHQK-AWLYTNEPKAGPLGGKVLQGKALSYNNILDADAAWRAV---- 261

Query: 688 EALSLPAAASFKHVSPAGAA 747
              + PAA   KH++P G A
Sbjct: 262 SMFTKPAAVVVKHLTPCGLA 281


>UniRef50_Q550I9 Cluster: AICAR transformylase / IMP cyclohydrolase;
           n=2; Dictyostelium discoideum|Rep: AICAR transformylase
           / IMP cyclohydrolase - Dictyostelium discoideum AX4
          Length = 542

 Score = 96.3 bits (229), Expect = 7e-19
 Identities = 48/86 (55%), Positives = 60/86 (69%), Gaps = 1/86 (1%)
 Frame = +1

Query: 1   SECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLS-DS 177
           S  G  LI++GGTA+SL + GL VQ VSD+T  PEML GRVKTLHP +H G+LAR     
Sbjct: 21  SSKGFNLISTGGTAKSLVDNGLKVQQVSDVTEYPEMLDGRVKTLHPKIHGGLLARPELAH 80

Query: 178 DQEDMKRQKYEMISVVVCNLYPFVQT 255
            Q D+ +   + IS+VV NLYPFV+T
Sbjct: 81  HQADLNKYNIKPISIVVVNLYPFVET 106



 Score = 46.0 bits (104), Expect = 0.001
 Identities = 24/63 (38%), Positives = 35/63 (55%), Gaps = 5/63 (7%)
 Frame = +2

Query: 329 TAKNHDRVTVVCDPADYDAVVKEIKE-----NKHHQTTLGTRQRLALKAFTHTSDYDLAI 493
           ++KN   V ++ DP+DY  + + I+      N     TL  R++LALKAF H   YD A+
Sbjct: 132 SSKNFQNVLIIVDPSDYKWIGERIQSSTDSTNVLSSITLEERKKLALKAFQHGCSYDAAV 191

Query: 494 SDY 502
           S Y
Sbjct: 192 SQY 194



 Score = 37.1 bits (82), Expect = 0.46
 Identities = 17/33 (51%), Positives = 22/33 (66%)
 Frame = +3

Query: 240 PVRPDVSKPDVTVADAVENIDIGGVTLLRAQPR 338
           P    VSK   T+ +A+ENIDIGG TL+RA  +
Sbjct: 102 PFVETVSKESTTLEEAIENIDIGGHTLIRASSK 134


>UniRef50_P74741 Cluster: Bifunctional purine biosynthesis protein
           purH [Includes: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]; n=49; root|Rep: Bifunctional purine
           biosynthesis protein purH [Includes:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)] - Synechocystis sp. (strain PCC
           6803)
          Length = 511

 Score = 96.3 bits (229), Expect = 7e-19
 Identities = 48/86 (55%), Positives = 60/86 (69%), Gaps = 1/86 (1%)
 Frame = +1

Query: 1   SECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLS-DS 177
           +E    LI+SGGTA++L+ AG+ V  VSD T APE+LGGRVKTLHP +H GILAR    S
Sbjct: 24  NEFQFDLISSGGTAKTLKEAGVPVTKVSDYTGAPEILGGRVKTLHPRIHGGILARRDLPS 83

Query: 178 DQEDMKRQKYEMISVVVCNLYPFVQT 255
           DQ D++      + +VV NLYPF QT
Sbjct: 84  DQADLEANDIRPLDLVVVNLYPFEQT 109



 Score = 43.6 bits (98), Expect = 0.005
 Identities = 23/59 (38%), Positives = 36/59 (61%)
 Frame = +2

Query: 329 TAKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYF 505
           TAKN    TV+ +P  Y+A ++ ++E    +  L  RQ+ A +AF  T+ YD AI++YF
Sbjct: 135 TAKNFAHTTVLTNPNQYEAYLQALQE--QGEIPLALRQQFAGEAFALTNAYDQAIANYF 191



 Score = 39.5 bits (88), Expect = 0.086
 Identities = 17/30 (56%), Positives = 22/30 (73%)
 Frame = +3

Query: 240 PVRPDVSKPDVTVADAVENIDIGGVTLLRA 329
           P    ++KP VTVA+AVE IDIGG  ++RA
Sbjct: 105 PFEQTIAKPGVTVAEAVEQIDIGGPAMIRA 134



 Score = 35.1 bits (77), Expect = 1.9
 Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 4/79 (5%)
 Frame = +1

Query: 523 GQAQLTLRYGMNPHQKPAQVFTTRDS---LPITTLNGAP-GFINLCDALNAWQLVKELKE 690
           G  +  LRYG NPHQ      T R++        L G    + NL D   A +++ E   
Sbjct: 206 GTLRQPLRYGENPHQSAGWYQTGREATGWAKAEKLQGKELSYNNLVDLEAARRIINEFD- 264

Query: 691 ALSLPAAASFKHVSPAGAA 747
            +  PAA   KH +P G A
Sbjct: 265 -VREPAAVILKHTNPCGVA 282


>UniRef50_Q9RW01 Cluster: Bifunctional purine biosynthesis protein
           purH [Includes: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]; n=3; Bacteria|Rep: Bifunctional
           purine biosynthesis protein purH [Includes:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)] - Deinococcus radiodurans
          Length = 510

 Score = 93.5 bits (222), Expect = 5e-18
 Identities = 75/256 (29%), Positives = 109/256 (42%), Gaps = 10/256 (3%)
 Frame = +1

Query: 10  GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQED 189
           G +L+++GGT  +L  AG+ V+ VSD+T  PEML GRVKTLHPA+H GILAR        
Sbjct: 26  GWELLSTGGTFATLSGAGIPVRQVSDVTGFPEMLDGRVKTLHPAIHGGILARREAGHLGQ 85

Query: 190 MKRQKYEMISVVVCNLYPFVQTYL--XXXXXXXXXXXXXXXAA*PSCAHSQEXXXXXXXX 363
           +  Q    I +V  NLYPF +T                   A   S A + +        
Sbjct: 86  LAAQDIGTIDLVCVNLYPFRETVARGAPDPEVIENIDIGGPAMIRSAAKNHDAVLVLVDP 145

Query: 364 XXXXXXCCSQRN--QREQTSSDDFGHKAEISPEGVHSYFGL*PRHIGLLPQQYSPGQAQL 537
                    + +  +R + ++  + H +E          G        LP+  S    + 
Sbjct: 146 ADYALALQDEVSPAERRRLAAKAYRHTSEYDAAITAYLSGESDELPTQLPEHLSLDLTRT 205

Query: 538 T-LRYGMNPHQKPAQVFTTRDS----LPITTLNGAP-GFINLCDALNAWQLVKELKEALS 699
             +RYG NPHQ P  ++   ++    +    + G P  F N  DA  AW L +EL     
Sbjct: 206 AQVRYGENPHQ-PGAIYRWGNARGPVIDAQVVAGKPMSFNNYADADAAWSLCQELAAQEQ 264

Query: 700 LPAAASFKHVSPAGAA 747
                + KH +P G A
Sbjct: 265 GAVCVAVKHANPCGVA 280



 Score = 50.8 bits (116), Expect = 4e-05
 Identities = 26/57 (45%), Positives = 36/57 (63%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDY 502
           AKNHD V V+ DPADY   +++       + +   R+RLA KA+ HTS+YD AI+ Y
Sbjct: 133 AKNHDAVLVLVDPADYALALQD-------EVSPAERRRLAAKAYRHTSEYDAAITAY 182


>UniRef50_Q2JR47 Cluster: Bifunctional purine biosynthesis protein
           PurH; n=12; Bacteria|Rep: Bifunctional purine
           biosynthesis protein PurH - Synechococcus sp. (strain
           JA-3-3Ab) (Cyanobacteria bacteriumYellowstone A-Prime)
          Length = 537

 Score = 93.1 bits (221), Expect = 7e-18
 Identities = 47/85 (55%), Positives = 59/85 (69%), Gaps = 1/85 (1%)
 Frame = +1

Query: 4   ECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLS-DSD 180
           E G QL++SGGTA++L  AG+ V  VS+ T APE+LGGRVKTLHP +H GILARL    D
Sbjct: 30  EHGFQLLSSGGTAKALSEAGIPVTPVSEHTGAPEILGGRVKTLHPRIHGGILARLERRED 89

Query: 181 QEDMKRQKYEMISVVVCNLYPFVQT 255
           + D++      I +VV N YPF QT
Sbjct: 90  RADLEALGIPPIQLVVVNFYPFEQT 114



 Score = 38.7 bits (86), Expect = 0.15
 Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 2/68 (2%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYF-R 508
           AKN+  VTV+ DP+ Y   ++ +         L  R + A +AF     YD AI DY  R
Sbjct: 141 AKNYPHVTVLTDPSQYPQYLQLLSSPSSEAERLAFRFQCARRAFEQVLAYDRAIVDYLTR 200

Query: 509 SN-TRPGK 529
           S  +RP +
Sbjct: 201 SELSRPSQ 208


>UniRef50_Q2JI00 Cluster: Bifunctional purine biosynthesis protein
           PurH; n=1; Synechococcus sp. JA-2-3B'a(2-13)|Rep:
           Bifunctional purine biosynthesis protein PurH -
           Synechococcus sp. (strain JA-2-3B'a(2-13))
           (Cyanobacteria bacteriumYellowstone B-Prime)
          Length = 577

 Score = 92.7 bits (220), Expect = 9e-18
 Identities = 48/85 (56%), Positives = 59/85 (69%), Gaps = 1/85 (1%)
 Frame = +1

Query: 4   ECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDS-D 180
           E G QL++SGGTA++L  AG+ V  VS  T APE+LGGRVKTLHP +H GILARL  S D
Sbjct: 38  EHGFQLLSSGGTAKALSEAGIPVTPVSAHTGAPEILGGRVKTLHPRIHGGILARLECSED 97

Query: 181 QEDMKRQKYEMISVVVCNLYPFVQT 255
           + D++      I +VV N YPF QT
Sbjct: 98  RADLEALGIPPIQLVVVNFYPFEQT 122



 Score = 32.7 bits (71), Expect = 9.9
 Identities = 19/57 (33%), Positives = 27/57 (47%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDY 502
           AKN+  VTV+ DP+ Y   ++ +         L  R + A +AF     YD AI  Y
Sbjct: 149 AKNYPYVTVLTDPSQYPRYLQLLSGAYGETERLAFRFQCARRAFEQVLAYDRAIVTY 205


>UniRef50_A5E8X1 Cluster: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase /IMP cyclohydrolase; n=4;
           Bacteria|Rep: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase /IMP cyclohydrolase - Bradyrhizobium
           sp. (strain BTAi1 / ATCC BAA-1182)
          Length = 530

 Score = 91.9 bits (218), Expect = 2e-17
 Identities = 45/83 (54%), Positives = 60/83 (72%), Gaps = 1/83 (1%)
 Frame = +1

Query: 10  GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILA-RLSDSDQE 186
           G++LI++GGTA+++ +AGL V+DVSD+T  PEM+ GRVKTLHP VH G+LA R +D   E
Sbjct: 32  GIELISTGGTAKAIADAGLKVKDVSDLTGFPEMMDGRVKTLHPKVHGGLLAIRGNDEHAE 91

Query: 187 DMKRQKYEMISVVVCNLYPFVQT 255
            MK      I ++V NLYPF  T
Sbjct: 92  AMKTHGIAPIDLLVVNLYPFEAT 114



 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 29/68 (42%), Positives = 45/68 (66%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRS 511
           +KNH+ V VV D  DYDAV++++  ++   TTL  R+RLA KA+  T+ YD AIS++F +
Sbjct: 140 SKNHEDVAVVVDVNDYDAVLEDLARHEG-STTLLLRRRLAAKAYARTAAYDAAISNWFAA 198

Query: 512 NTRPGKPN 535
             +   P+
Sbjct: 199 TIQNDAPD 206


>UniRef50_Q8ZAR3 Cluster: Bifunctional purine biosynthesis protein
           purH [Includes: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]; n=59; Proteobacteria|Rep:
           Bifunctional purine biosynthesis protein purH [Includes:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)] - Yersinia pestis
          Length = 529

 Score = 91.5 bits (217), Expect = 2e-17
 Identities = 46/85 (54%), Positives = 58/85 (68%)
 Frame = +1

Query: 1   SECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSD 180
           S+ G++L+++GGTAR L +AGL V +VSD T  PEM+ GRVKTLHP VH GIL R    D
Sbjct: 28  SQRGIELLSTGGTARLLADAGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGR-RGQD 86

Query: 181 QEDMKRQKYEMISVVVCNLYPFVQT 255
              M +   + I +VV NLYPF QT
Sbjct: 87  DGIMAQHGIQPIDIVVVNLYPFAQT 111



 Score = 54.4 bits (125), Expect = 3e-06
 Identities = 27/64 (42%), Positives = 38/64 (59%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRS 511
           AKNH  V +V   +DY A++ E+ +N     T  TR  LA+KAF HT+ YD  I++YF +
Sbjct: 138 AKNHKDVAIVVKSSDYPAIITEL-DNNDGSLTYPTRFNLAIKAFEHTAAYDSMIANYFGT 196

Query: 512 NTRP 523
              P
Sbjct: 197 LVPP 200



 Score = 38.7 bits (86), Expect = 0.15
 Identities = 16/30 (53%), Positives = 23/30 (76%)
 Frame = +3

Query: 240 PVRPDVSKPDVTVADAVENIDIGGVTLLRA 329
           P    V++PD ++ DAVENIDIGG T++R+
Sbjct: 107 PFAQTVARPDCSLEDAVENIDIGGPTMVRS 136


>UniRef50_Q7X311 Cluster: Putative AICAR transformylase; n=1;
           uncultured Acidobacteria bacterium|Rep: Putative AICAR
           transformylase - uncultured Acidobacteria bacterium
          Length = 571

 Score = 90.2 bits (214), Expect = 5e-17
 Identities = 41/82 (50%), Positives = 60/82 (73%), Gaps = 1/82 (1%)
 Frame = +1

Query: 13  LQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGIL-ARLSDSDQED 189
           ++++++GGTA++LR AG+ V+DVSD+T  PEM+ GRVKTLHP +H G+L  R S S +  
Sbjct: 37  IEIVSTGGTAKTLREAGIEVRDVSDVTGFPEMMDGRVKTLHPKIHGGLLGVRDSPSHESS 96

Query: 190 MKRQKYEMISVVVCNLYPFVQT 255
           M+    E I +VV +LYPF +T
Sbjct: 97  MREHGIEPIDMVVIDLYPFERT 118



 Score = 36.3 bits (80), Expect = 0.81
 Identities = 19/57 (33%), Positives = 32/57 (56%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDY 502
           AKN   V V+ + ++Y  + +E++ +     +L TR+RLA  AF  T+ YD  +  Y
Sbjct: 145 AKNFHSVAVITNTSEYGPIAEELRAHDC-SLSLHTRRRLAEIAFQRTAQYDSIVFGY 200



 Score = 34.7 bits (76), Expect = 2.5
 Identities = 28/73 (38%), Positives = 32/73 (43%), Gaps = 3/73 (4%)
 Frame = +1

Query: 538 TLRYGMNPHQKPAQVFTTRDS--LPITTLNGAP-GFINLCDALNAWQLVKELKEALSLPA 708
           +LRYG NPHQ      T   S       L+G    F N  DA  AW LV +  E     A
Sbjct: 274 SLRYGENPHQIAGLYKTAAQSGIANAELLSGKEMSFNNYVDADAAWHLVCDFDEL----A 329

Query: 709 AASFKHVSPAGAA 747
            A  KH + AG A
Sbjct: 330 CAIIKHTNAAGVA 342


>UniRef50_O67775 Cluster: Bifunctional purine biosynthesis protein
           purH [Includes: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]; n=9; Bacteria|Rep: Bifunctional
           purine biosynthesis protein purH [Includes:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)] - Aquifex aeolicus
          Length = 506

 Score = 89.4 bits (212), Expect = 8e-17
 Identities = 42/82 (51%), Positives = 61/82 (74%), Gaps = 1/82 (1%)
 Frame = +1

Query: 4   ECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILAR-LSDSD 180
           E G +++++GGTA+ LR  G++V++VS+IT  PE+L GRVKTLHP VH GIL R   + D
Sbjct: 22  ELGYEIVSTGGTAKYLREKGISVKEVSEITGFPEILEGRVKTLHPVVHGGILFRDWVEKD 81

Query: 181 QEDMKRQKYEMISVVVCNLYPF 246
           +E++++   + I VVV NLYPF
Sbjct: 82  KEEIEKHGIKPIDVVVVNLYPF 103



 Score = 50.8 bits (116), Expect = 4e-05
 Identities = 27/59 (45%), Positives = 37/59 (62%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFR 508
           AKN  RV ++ DP DYD V++++K+      TL  R  LA KAF+HT+ YD  IS  F+
Sbjct: 132 AKNFFRVVILVDPEDYDWVIEKLKKG---NLTLQDRAYLAWKAFSHTAYYDGVISQAFK 187


>UniRef50_A7HM64 Cluster: IMP cyclohydrolase; n=1; Fervidobacterium
           nodosum Rt17-B1|Rep: IMP cyclohydrolase -
           Fervidobacterium nodosum Rt17-B1
          Length = 429

 Score = 88.6 bits (210), Expect = 1e-16
 Identities = 43/80 (53%), Positives = 59/80 (73%), Gaps = 1/80 (1%)
 Frame = +1

Query: 10  GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSD-SDQE 186
           G+++I++GGTA+ L +AG+ V+ VSD+T  PE+LGGRVKTLHP +  GILA L D S  +
Sbjct: 27  GVEIISTGGTAKLLSDAGIPVKQVSDVTGFPEILGGRVKTLHPKIFGGILADLGDKSHVK 86

Query: 187 DMKRQKYEMISVVVCNLYPF 246
           D++    E I +VV NLYPF
Sbjct: 87  DLRDNFIEPIDLVVVNLYPF 106



 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 29/54 (53%), Positives = 32/54 (59%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAI 493
           AKNH  V VVCDPADYD V+K I  +      L  R+  ALKAF HT  YD  I
Sbjct: 135 AKNHRNVVVVCDPADYDKVIKSI--DLCGDVQLHDRRMFALKAFYHTMKYDATI 186


>UniRef50_A7DF55 Cluster: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase/IMP cyclohydrolase; n=3;
           Alphaproteobacteria|Rep:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase/IMP cyclohydrolase - Methylobacterium
           extorquens PA1
          Length = 581

 Score = 88.2 bits (209), Expect = 2e-16
 Identities = 43/86 (50%), Positives = 61/86 (70%), Gaps = 1/86 (1%)
 Frame = +1

Query: 1   SECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILA-RLSDS 177
           S+ G++L+++GGT R+L  AGL V++VS++TR PEM+ GRVKTLHPAVH G+LA R +  
Sbjct: 78  SQRGVELVSTGGTHRALTEAGLAVREVSELTRFPEMMDGRVKTLHPAVHGGLLAVRDNPE 137

Query: 178 DQEDMKRQKYEMISVVVCNLYPFVQT 255
            Q  +       I ++V NLYPF +T
Sbjct: 138 HQAALAAHGIGAIDLLVVNLYPFEET 163



 Score = 53.6 bits (123), Expect = 5e-06
 Identities = 27/57 (47%), Positives = 39/57 (68%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDY 502
           AKNH  V VV D +DY A++ E+ E+  + T   TR+RLA KAF+ T+ YD AI+++
Sbjct: 189 AKNHADVAVVVDVSDYGAILAELAEHDGNLTAT-TRRRLAQKAFSRTASYDAAIANW 244



 Score = 33.5 bits (73), Expect = 5.7
 Identities = 28/80 (35%), Positives = 34/80 (42%), Gaps = 5/80 (6%)
 Frame = +1

Query: 523 GQAQLTLRYGMNPHQKPAQVFTTRDSLP-ITTLNGAPG----FINLCDALNAWQLVKELK 687
           G    +LRYG NPHQ  A         P I T     G    + NL D   A++ V E  
Sbjct: 262 GTLAQSLRYGENPHQSAAFYRLPGTLRPGIATARQVQGKELSYNNLNDTDAAYECVAEFD 321

Query: 688 EALSLPAAASFKHVSPAGAA 747
            A +  A A  KH +P G A
Sbjct: 322 PART-AAVAIIKHANPCGVA 340


>UniRef50_A0JTW4 Cluster: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase/IMP cyclohydrolase; n=2;
           Arthrobacter|Rep:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase/IMP cyclohydrolase - Arthrobacter sp.
           (strain FB24)
          Length = 559

 Score = 88.2 bits (209), Expect = 2e-16
 Identities = 41/85 (48%), Positives = 59/85 (69%), Gaps = 1/85 (1%)
 Frame = +1

Query: 4   ECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILA-RLSDSD 180
           E G++++++G TA+ +  AG+ VQ+V ++T +PEML GRVKTLHP VH GILA R   + 
Sbjct: 33  EAGVKIVSTGSTAKKIAAAGIPVQEVEEVTGSPEMLDGRVKTLHPRVHGGILADRRVPAH 92

Query: 181 QEDMKRQKYEMISVVVCNLYPFVQT 255
            E +   + E   +VV NLYPFV+T
Sbjct: 93  METLAGMEIEAFDLVVVNLYPFVET 117



 Score = 50.4 bits (115), Expect = 5e-05
 Identities = 28/60 (46%), Positives = 34/60 (56%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRS 511
           AKNH  V +V DP  Y  VV+   E       L TRQRLA KAF HT+ YD A++ +  S
Sbjct: 143 AKNHAAVAIVTDPNFYGDVVRAAAEGGFD---LKTRQRLAAKAFAHTASYDTAVATWTAS 199


>UniRef50_Q1V178 Cluster: Bifunctional purine biosynthesis protein;
           n=2; Candidatus Pelagibacter ubique|Rep: Bifunctional
           purine biosynthesis protein - Candidatus Pelagibacter
           ubique HTCC1002
          Length = 518

 Score = 86.6 bits (205), Expect = 6e-16
 Identities = 38/82 (46%), Positives = 60/82 (73%), Gaps = 1/82 (1%)
 Frame = +1

Query: 13  LQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSD-SDQED 189
           ++LI+SGGT + ++      Q+VS+ T +PE+LGGRVKTLHP +HAGIL++ +D S  ++
Sbjct: 36  IELISSGGTFKEIKKLKFKCQEVSEYTGSPEILGGRVKTLHPKIHAGILSKRNDKSHTKE 95

Query: 190 MKRQKYEMISVVVCNLYPFVQT 255
           +K  +Y+ I +V+ N YPF +T
Sbjct: 96  LKANQYDEIDLVIVNFYPFEKT 117



 Score = 50.8 bits (116), Expect = 4e-05
 Identities = 22/58 (37%), Positives = 40/58 (68%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYF 505
           AKN++ VTV+     Y+ ++ E++ NK   T++  R++++L+AF+ T+ YD  IS+YF
Sbjct: 143 AKNYNDVTVITSSDQYETLINELENNKG-STSIEFREKMSLEAFSETAYYDAVISNYF 199


>UniRef50_Q8PYG4 Cluster: Formyltransferase
           phosphoribosylaminoimidazolecarboxamide; n=4;
           Methanosarcinaceae|Rep: Formyltransferase
           phosphoribosylaminoimidazolecarboxamide - Methanosarcina
           mazei (Methanosarcina frisia)
          Length = 538

 Score = 86.6 bits (205), Expect = 6e-16
 Identities = 38/80 (47%), Positives = 57/80 (71%), Gaps = 1/80 (1%)
 Frame = +1

Query: 10  GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILA-RLSDSDQE 186
           G+++I++GGTA+ LR+A + V DVS++T  PEM+GGRVKTLHP +H G+L  R S    E
Sbjct: 26  GVKIISTGGTAKILRDADIEVTDVSEVTGYPEMMGGRVKTLHPRIHGGLLCLRESKEQME 85

Query: 187 DMKRQKYEMISVVVCNLYPF 246
           +  ++   +I ++  NLYPF
Sbjct: 86  EAAKEDISLIDLIAVNLYPF 105



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 27/57 (47%), Positives = 37/57 (64%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDY 502
           AKN+  VTV+ DP+DY  ++KE++ +        TR  LA+KAF HT+DYD AI  Y
Sbjct: 135 AKNYRSVTVLSDPSDYGRILKELRSSGIISDK--TRAELAVKAFRHTADYDAAIDTY 189



 Score = 35.5 bits (78), Expect = 1.4
 Identities = 16/30 (53%), Positives = 22/30 (73%)
 Frame = +3

Query: 240 PVRPDVSKPDVTVADAVENIDIGGVTLLRA 329
           P    VS+ +V + +A+ENIDIGG TLLR+
Sbjct: 104 PFEITVSRENVELEEAIENIDIGGPTLLRS 133


>UniRef50_UPI00015BCE7E Cluster: UPI00015BCE7E related cluster; n=1;
           unknown|Rep: UPI00015BCE7E UniRef100 entry - unknown
          Length = 506

 Score = 86.2 bits (204), Expect = 8e-16
 Identities = 41/80 (51%), Positives = 56/80 (70%), Gaps = 1/80 (1%)
 Frame = +1

Query: 10  GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLS-DSDQE 186
           G ++++SGGT   L+NAG+   +VS++T   E+LGGRVKTLHPA+H GIL R   + D E
Sbjct: 24  GYEILSSGGTYTYLKNAGVDAIEVSEVTGFREILGGRVKTLHPAIHGGILFREDVEKDLE 83

Query: 187 DMKRQKYEMISVVVCNLYPF 246
           ++K    E I +VV NLYPF
Sbjct: 84  EIKENSIEPIDIVVVNLYPF 103



 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 27/58 (46%), Positives = 35/58 (60%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYF 505
           AKNH RV+V+ D  DY   ++++K N   Q     R+ LALKAF  TS YD  I+ YF
Sbjct: 132 AKNHKRVSVLTDIEDYGWFIEKLKMNAVSQQD---RKYLALKAFWLTSYYDAVIASYF 186


>UniRef50_A1K9K5 Cluster: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase/IMP cyclohydrolase; n=2; Bacteria|Rep:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase/IMP cyclohydrolase - Azoarcus sp.
           (strain BH72)
          Length = 527

 Score = 85.8 bits (203), Expect = 1e-15
 Identities = 45/83 (54%), Positives = 56/83 (67%), Gaps = 1/83 (1%)
 Frame = +1

Query: 10  GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQED 189
           G++L+++GGTA  LR+AGL V DVS+ T  PEML GRVKTLHP VH GILAR   ++  D
Sbjct: 27  GIKLLSTGGTAALLRDAGLPVTDVSEHTGFPEMLDGRVKTLHPKVHGGILARRDLAEHMD 86

Query: 190 -MKRQKYEMISVVVCNLYPFVQT 255
            +       I +VV NLYPF  T
Sbjct: 87  TIAAHDISRIDLVVVNLYPFQAT 109



 Score = 50.8 bits (116), Expect = 4e-05
 Identities = 29/61 (47%), Positives = 38/61 (62%), Gaps = 4/61 (6%)
 Frame = +2

Query: 332 AKNHDR----VTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISD 499
           AKNH      V +V DP DY  +V E+K N +   +  TR  LA+KAFTHT+ YD AIS+
Sbjct: 136 AKNHGTEAGGVGIVTDPEDYAGIVAELKANAN-TLSYKTRFALAVKAFTHTARYDSAISN 194

Query: 500 Y 502
           +
Sbjct: 195 H 195



 Score = 44.0 bits (99), Expect = 0.004
 Identities = 22/48 (45%), Positives = 30/48 (62%), Gaps = 3/48 (6%)
 Frame = +3

Query: 240 PVRPDVSKPDVTVADAVENIDIGGVTLLRAQPR---TTTGSPSSVTRP 374
           P +  V++PD T+ DA+ENIDIGG T++RA  +   T  G    VT P
Sbjct: 105 PFQATVARPDCTLEDAIENIDIGGPTMVRAAAKNHGTEAGGVGIVTDP 152



 Score = 33.5 bits (73), Expect = 5.7
 Identities = 26/74 (35%), Positives = 32/74 (43%), Gaps = 5/74 (6%)
 Frame = +1

Query: 541 LRYGMNPHQKPA---QVFTTRDSL-PITTLNGAP-GFINLCDALNAWQLVKELKEALSLP 705
           LRYG NPHQ  A   +       +   T L G    + N+ DA  AW+ VK    A    
Sbjct: 226 LRYGENPHQSAAFYKEPGAAEGGIASYTQLQGKELSYNNIADADAAWECVK----AFDTG 281

Query: 706 AAASFKHVSPAGAA 747
           A    KH +P G A
Sbjct: 282 ACVIVKHANPCGVA 295


>UniRef50_Q9FPL3 Cluster: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase/IMP cyclohydrolase; n=14;
           Viridiplantae|Rep:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase/IMP cyclohydrolase - Nicotiana tabacum
           (Common tobacco)
          Length = 612

 Score = 84.6 bits (200), Expect = 2e-15
 Identities = 40/82 (48%), Positives = 56/82 (68%), Gaps = 1/82 (1%)
 Frame = +1

Query: 4   ECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARL-SDSD 180
           E G  ++++GGT+ +L  AG++V  V ++TR PEML GRVKTLHP+VH GILAR   +  
Sbjct: 110 ELGYTIVSTGGTSSALEGAGVSVTKVEELTRFPEMLDGRVKTLHPSVHGGILARRDQEHH 169

Query: 181 QEDMKRQKYEMISVVVCNLYPF 246
            E +++ +     VVV NLYPF
Sbjct: 170 MEALEKHEIGTFDVVVVNLYPF 191



 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 32/84 (38%), Positives = 46/84 (54%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRS 511
           AKNH  V VV D  DY A+++ ++ +   Q     R++LA KAF H + YD A+S++   
Sbjct: 222 AKNHRDVLVVVDSEDYPALLEFLRGDNDDQQF---RRKLAWKAFQHVASYDSAVSEWLWK 278

Query: 512 NTRPGKPN*P*DTV*THIRSRPRY 583
            T  G    P  TV  H++S  RY
Sbjct: 279 QT-VGDKFPPGLTVPLHLKSLLRY 301


>UniRef50_Q83EI4 Cluster: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase/IMP cyclohydrolase; n=5; Coxiella
           burnetii|Rep: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase/IMP cyclohydrolase - Coxiella burnetii
          Length = 526

 Score = 84.2 bits (199), Expect = 3e-15
 Identities = 41/83 (49%), Positives = 57/83 (68%)
 Frame = +1

Query: 7   CGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQE 186
           CG+++IA+GGTA  L+   L V DV   T  PE++ GRVKTLHP +HAG+LAR    D++
Sbjct: 34  CGVEIIATGGTAELLKQHQLPVIDVFTYTGFPEIMDGRVKTLHPKIHAGLLAR-RGIDEK 92

Query: 187 DMKRQKYEMISVVVCNLYPFVQT 255
            + +   + I ++V NLYPFVQT
Sbjct: 93  TLDQHAIKPIDLLVVNLYPFVQT 115



 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 31/57 (54%), Positives = 37/57 (64%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDY 502
           AKN   VTVV DP DY  +++EIK + H  TTL TR+RLA K F H S YD  I+ Y
Sbjct: 142 AKNFAAVTVVVDPEDYSRILEEIKTH-HGSTTLSTRKRLAQKTFEHLSYYDAHIATY 197



 Score = 39.9 bits (89), Expect = 0.065
 Identities = 30/77 (38%), Positives = 38/77 (49%), Gaps = 5/77 (6%)
 Frame = +1

Query: 532 QLTLRYGMNPHQKPAQVFT----TRDSLPITTLNGAP-GFINLCDALNAWQLVKELKEAL 696
           ++ LRYG NPHQ  A        +        L G P  F NL D+  A++ V E   +L
Sbjct: 218 KIDLRYGENPHQTAALYSIDPPLSHSLAEAQLLQGKPLSFNNLLDSDCAYRCVYE--GSL 275

Query: 697 SLPAAASFKHVSPAGAA 747
           S PA    KH +PAGAA
Sbjct: 276 SEPACVIVKHATPAGAA 292


>UniRef50_Q0YKD5 Cluster: IMP cyclohydrolase; n=2; Geobacter|Rep:
           IMP cyclohydrolase - Geobacter sp. FRC-32
          Length = 388

 Score = 84.2 bits (199), Expect = 3e-15
 Identities = 40/72 (55%), Positives = 48/72 (66%)
 Frame = +1

Query: 532 QLTLRYGMNPHQKPAQVFTTRDSLPITTLNGAPGFINLCDALNAWQLVKELKEALSLPAA 711
           ++ L+YG N HQ PA +    +S     LNG P +IN+ DAL AWQL +ELK A S P A
Sbjct: 2   EIKLKYGCNSHQTPANLIIPENS-GFQVLNGTPSYINILDALGAWQLARELKIATSKPGA 60

Query: 712 ASFKHVSPAGAA 747
           ASFKH SPAGAA
Sbjct: 61  ASFKHTSPAGAA 72


>UniRef50_Q9PC10 Cluster: Bifunctional purine biosynthesis protein
           purH [Includes: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]; n=214; cellular organisms|Rep:
           Bifunctional purine biosynthesis protein purH [Includes:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)] - Xylella fastidiosa
          Length = 527

 Score = 84.2 bits (199), Expect = 3e-15
 Identities = 40/80 (50%), Positives = 55/80 (68%)
 Frame = +1

Query: 13  LQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQEDM 192
           ++L+++GGTA  +R AGL VQDV+D+T  PEM+ GRVKTLHP VH G+L R +  D   M
Sbjct: 33  IELLSTGGTATIIREAGLPVQDVADLTGFPEMMDGRVKTLHPMVHGGLLGR-AGIDDAVM 91

Query: 193 KRQKYEMISVVVCNLYPFVQ 252
            +     I +++ NLYPF Q
Sbjct: 92  AKHGIAPIDLLILNLYPFEQ 111



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 24/60 (40%), Positives = 33/60 (55%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRS 511
           AKN  RV V   P  Y  ++ E++ + H Q +   R  LA+ AF H + YD AIS+Y  S
Sbjct: 139 AKNFARVAVATSPDQYPDLLAELQAH-HGQLSAEKRFALAVAAFNHVAQYDAAISNYLSS 197



 Score = 35.5 bits (78), Expect = 1.4
 Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 6/87 (6%)
 Frame = +1

Query: 505 PQQYSPGQAQLT-LRYGMNPHQKPA---QVFTTRDSL-PITTLNGAP-GFINLCDALNAW 666
           P Q +    ++T LRYG NPHQ  A    V     +L     L G    + NL DA  AW
Sbjct: 212 PAQLNNTFVKMTELRYGENPHQTGAFYRDVHPQPGTLATFQQLQGKTLSYNNLVDADAAW 271

Query: 667 QLVKELKEALSLPAAASFKHVSPAGAA 747
           + V++ +     PA    KH +P G A
Sbjct: 272 ECVRQFE----APACVIVKHANPCGVA 294



 Score = 33.9 bits (74), Expect = 4.3
 Identities = 15/30 (50%), Positives = 20/30 (66%)
 Frame = +3

Query: 240 PVRPDVSKPDVTVADAVENIDIGGVTLLRA 329
           P     +K D T+ADAV+ IDIGG  +LR+
Sbjct: 108 PFEQITAKKDCTLADAVDTIDIGGPAMLRS 137


>UniRef50_P12048 Cluster: Bifunctional purine biosynthesis protein
           purH [Includes: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]; n=71; Bacteria|Rep: Bifunctional
           purine biosynthesis protein purH [Includes:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)] - Bacillus subtilis
          Length = 512

 Score = 83.8 bits (198), Expect = 4e-15
 Identities = 74/265 (27%), Positives = 122/265 (46%), Gaps = 18/265 (6%)
 Frame = +1

Query: 1   SECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILA-RLSDS 177
           +E G+++I++GGT + L+  G+ V  +S++T  PE++ GR+KTLHP +H G+LA R ++ 
Sbjct: 24  TELGVEVISTGGTKKLLQENGVDVIGISEVTGFPEIMDGRLKTLHPNIHGGLLAVRGNEE 83

Query: 178 DQEDMKRQKYEMISVVVCNLYPFVQTYLXXXXXXXXXXXXXXXAA*PSCAHSQEXXXXXX 357
               +     + I +VV NLYPF +T +                  P    +        
Sbjct: 84  HMAQINEHGIQPIDLVVVNLYPFKET-ISKEDVTYEEAIENIDIGGPGMLRAASKNHQDV 142

Query: 358 XXXXXXXXCCSQRNQREQTSSDDFGHKAEISPE---GVHSYFGL*PRHIGLLPQQYSPGQ 528
                        NQ ++  S     K E++ +      +Y  L   ++  +  +  P Q
Sbjct: 143 TVIVDPADYSPVLNQIKEEGSVSLQKKRELAAKVFRHTAAYDALIADYLTNVVGEKEPEQ 202

Query: 529 AQLT------LRYGMNPHQKPAQVFTTRDSLPI-------TTLNGAP-GFINLCDALNAW 666
             +T      LRYG NPHQ+ A  + T  +LP+         L+G    + N+ DA  A 
Sbjct: 203 FTVTFEKKQSLRYGENPHQE-ATFYQT--ALPVKGSIAQAEQLHGKELSYNNIKDADAAV 259

Query: 667 QLVKELKEALSLPAAASFKHVSPAG 741
           Q+V+E  E    PAA + KH++P G
Sbjct: 260 QIVREFTE----PAAVAVKHMNPCG 280



 Score = 56.8 bits (131), Expect = 5e-07
 Identities = 27/57 (47%), Positives = 36/57 (63%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDY 502
           +KNH  VTV+ DPADY  V+ +IKE      +L  ++ LA K F HT+ YD  I+DY
Sbjct: 136 SKNHQDVTVIVDPADYSPVLNQIKE--EGSVSLQKKRELAAKVFRHTAAYDALIADY 190



 Score = 39.1 bits (87), Expect = 0.11
 Identities = 17/30 (56%), Positives = 22/30 (73%)
 Frame = +3

Query: 240 PVRPDVSKPDVTVADAVENIDIGGVTLLRA 329
           P +  +SK DVT  +A+ENIDIGG  +LRA
Sbjct: 105 PFKETISKEDVTYEEAIENIDIGGPGMLRA 134


>UniRef50_A2SS05 Cluster: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase/IMP cyclohydrolase; n=3;
           Methanomicrobiales|Rep:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase/IMP cyclohydrolase -
           Methanocorpusculum labreanum (strain ATCC 43576 / DSM
           4855 / Z)
          Length = 497

 Score = 83.4 bits (197), Expect = 5e-15
 Identities = 39/76 (51%), Positives = 53/76 (69%)
 Frame = +1

Query: 19  LIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQEDMKR 198
           +++SGGTA++LR AG+  +DVS+ T+ PEM+ GRVKTLHP VH G+L R    D + MK 
Sbjct: 28  ILSSGGTAKALREAGIPAKDVSEYTQFPEMMDGRVKTLHPKVHGGLLGR-RGIDDDVMKA 86

Query: 199 QKYEMISVVVCNLYPF 246
              E I ++  NLYPF
Sbjct: 87  HFIEPIDILCVNLYPF 102



 Score = 46.4 bits (105), Expect = 8e-04
 Identities = 25/57 (43%), Positives = 34/57 (59%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDY 502
           +KN+  V V+ DP+DY   ++ IK       T   + RLA KAFT T+ YD AIS+Y
Sbjct: 131 SKNYKDVAVLTDPSDYPMAIEAIKTGGF---TSEQKLRLATKAFTRTAAYDAAISNY 184


>UniRef50_P67543 Cluster: Bifunctional purine biosynthesis protein
           purH [Includes: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]; n=18; Staphylococcus|Rep:
           Bifunctional purine biosynthesis protein purH [Includes:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)] - Staphylococcus aureus (strain Mu50
           / ATCC 700699)
          Length = 492

 Score = 83.4 bits (197), Expect = 5e-15
 Identities = 41/86 (47%), Positives = 56/86 (65%), Gaps = 1/86 (1%)
 Frame = +1

Query: 1   SECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILA-RLSDS 177
           ++   +L ++GGT R L  A + V+ VSD+T  PE++ GRVKTLHPAVH GILA R    
Sbjct: 22  TQLNYELYSTGGTKRILDEANVPVRSVSDLTHFPEIMDGRVKTLHPAVHGGILADRNKPQ 81

Query: 178 DQEDMKRQKYEMISVVVCNLYPFVQT 255
              ++  Q  ++I +VV NLYPF QT
Sbjct: 82  HLNELSEQHIDLIDMVVVNLYPFQQT 107



 Score = 46.4 bits (105), Expect = 8e-04
 Identities = 22/61 (36%), Positives = 36/61 (59%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRS 511
           AKN+  VT +  PADY  V+  ++ +   ++    RQ L +K F HT++YD AI  +F+ 
Sbjct: 134 AKNYKHVTTIVHPADYHEVLTRLRNDSLDESY---RQSLMIKVFEHTAEYDEAIVRFFKG 190

Query: 512 N 514
           +
Sbjct: 191 D 191



 Score = 42.3 bits (95), Expect = 0.012
 Identities = 18/30 (60%), Positives = 24/30 (80%)
 Frame = +3

Query: 240 PVRPDVSKPDVTVADAVENIDIGGVTLLRA 329
           P +  V+ PDVT+ +A+ENIDIGG T+LRA
Sbjct: 103 PFQQTVANPDVTMDEAIENIDIGGPTMLRA 132


>UniRef50_Q8CXK7 Cluster: Bifunctional purine biosynthesis protein
           purH [Includes: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]; n=34; Bacteria|Rep: Bifunctional
           purine biosynthesis protein purH [Includes:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)] - Oceanobacillus iheyensis
          Length = 510

 Score = 81.8 bits (193), Expect = 2e-14
 Identities = 37/85 (43%), Positives = 54/85 (63%), Gaps = 1/85 (1%)
 Frame = +1

Query: 4   ECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQ 183
           E G +++++GGT RS+  AG+ V  V ++T  PEML GRVKTLHP +H G+L + S+ + 
Sbjct: 24  ESGFEILSTGGTLRSIAEAGIDVTPVDEVTGFPEMLDGRVKTLHPMIHGGLLGKRSNHEH 83

Query: 184 -EDMKRQKYEMISVVVCNLYPFVQT 255
              M+      I +V  NLYPF +T
Sbjct: 84  LSQMEEHGIRSIDLVAVNLYPFKET 108



 Score = 49.6 bits (113), Expect = 8e-05
 Identities = 28/67 (41%), Positives = 35/67 (52%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRS 511
           AKN + V VV  P DY+ V+  I        T   RQ+LA K F HT+ YD  I++YF S
Sbjct: 135 AKNFEDVLVVTGPTDYNRVLAAITSETD---TYEFRQQLAAKVFRHTASYDAMIANYFLS 191

Query: 512 NTRPGKP 532
            T    P
Sbjct: 192 QTEEQYP 198



 Score = 38.3 bits (85), Expect = 0.20
 Identities = 16/30 (53%), Positives = 22/30 (73%)
 Frame = +3

Query: 240 PVRPDVSKPDVTVADAVENIDIGGVTLLRA 329
           P +  V KPDV+  D +ENIDIGG ++LR+
Sbjct: 104 PFKETVQKPDVSHQDIIENIDIGGPSMLRS 133


>UniRef50_Q95QQ5 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 420

 Score = 81.4 bits (192), Expect = 2e-14
 Identities = 35/49 (71%), Positives = 41/49 (83%)
 Frame = +1

Query: 601 LPITTLNGAPGFINLCDALNAWQLVKELKEALSLPAAASFKHVSPAGAA 747
           +PI  LNG+PG+IN+ D LN WQLVKEL +A  +PAAASFKHVSPAGAA
Sbjct: 1   MPIKVLNGSPGYINILDGLNGWQLVKELSDATKMPAAASFKHVSPAGAA 49


>UniRef50_P43852 Cluster: Bifunctional purine biosynthesis protein
           purH [Includes: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]; n=88; Bacteria|Rep: Bifunctional
           purine biosynthesis protein purH [Includes:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)] - Haemophilus influenzae
          Length = 532

 Score = 81.4 bits (192), Expect = 2e-14
 Identities = 42/82 (51%), Positives = 54/82 (65%)
 Frame = +1

Query: 10  GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQED 189
           G++L+++GGTA+ L    L V +VSD T  PEM+ GRVKTLHP VH GIL R   +D   
Sbjct: 30  GVKLLSTGGTAKLLAQNALPVIEVSDYTGFPEMMDGRVKTLHPKVHGGILGR-RGTDDAI 88

Query: 190 MKRQKYEMISVVVCNLYPFVQT 255
           M++   E I +VV NLYPF  T
Sbjct: 89  MQQHGIEGIDMVVVNLYPFAAT 110



 Score = 52.8 bits (121), Expect = 9e-06
 Identities = 25/64 (39%), Positives = 41/64 (64%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRS 511
           AKNH  V +V +  D++A++ E+ ++++   T  TR  LA+KAF HT+ YD  I++YF  
Sbjct: 137 AKNHKDVAIVVNNHDFNAILAEMDQHQN-SLTFETRFDLAIKAFEHTAQYDSMIANYFGQ 195

Query: 512 NTRP 523
             +P
Sbjct: 196 LVKP 199



 Score = 43.6 bits (98), Expect = 0.005
 Identities = 19/30 (63%), Positives = 24/30 (80%)
 Frame = +3

Query: 240 PVRPDVSKPDVTVADAVENIDIGGVTLLRA 329
           P    V+KPD T+ADAVENIDIGG T++R+
Sbjct: 106 PFAATVAKPDCTLADAVENIDIGGPTMVRS 135


>UniRef50_A6G003 Cluster: Bifunctional
           phosphoribosylaminoimidazolecarboxamide
           formyltransferase/IMP cyclohydrolase; n=1; Plesiocystis
           pacifica SIR-1|Rep: Bifunctional
           phosphoribosylaminoimidazolecarboxamide
           formyltransferase/IMP cyclohydrolase - Plesiocystis
           pacifica SIR-1
          Length = 543

 Score = 80.6 bits (190), Expect = 4e-14
 Identities = 36/81 (44%), Positives = 56/81 (69%)
 Frame = +1

Query: 13  LQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQEDM 192
           ++++++GGT R+L   G+ V  VS+ T APE+L GRVKTLHP +H GILA  +++ Q ++
Sbjct: 39  VEVLSTGGTYRALSELGVAVVKVSEFTGAPEILDGRVKTLHPKIHGGILALPTEAHQREL 98

Query: 193 KRQKYEMISVVVCNLYPFVQT 255
           +      I +V+ NLYPF +T
Sbjct: 99  ELHDIAPIDLVIVNLYPFRET 119



 Score = 46.4 bits (105), Expect = 8e-04
 Identities = 24/66 (36%), Positives = 37/66 (56%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRS 511
           AKN +RV V+ DP DY ++ + + E +        R+ +A KAF HT+ YD AI+ Y   
Sbjct: 146 AKNWNRVAVIVDPEDYSSLSEVLGETEGTLPE-SFRRNMARKAFAHTAAYDAAIASYLAR 204

Query: 512 NTRPGK 529
           +   G+
Sbjct: 205 HDDAGE 210



 Score = 46.0 bits (104), Expect = 0.001
 Identities = 36/94 (38%), Positives = 49/94 (52%), Gaps = 10/94 (10%)
 Frame = +1

Query: 496 GLLPQQ-YSPGQAQLTLRYGMNPHQKPAQVFTTRDSLPITTLNGAP-------GFINLCD 651
           G +P+  +  G++   LRYG NPHQ+     T+  S   T L+ A         + NL D
Sbjct: 215 GTIPEGLFVSGESVAELRYGENPHQQARFFATSYASDEATGLDQAIVHQGKALSYNNLLD 274

Query: 652 ALNAWQLVKELKEALSL--PAAASFKHVSPAGAA 747
           A  A  L+++LK  L     AAA FKH+SP GAA
Sbjct: 275 ADAALGLIRDLKAGLPEGGKAAAVFKHLSPCGAA 308



 Score = 41.1 bits (92), Expect = 0.028
 Identities = 17/30 (56%), Positives = 23/30 (76%)
 Frame = +3

Query: 240 PVRPDVSKPDVTVADAVENIDIGGVTLLRA 329
           P R  ++KP  + ADA+ENIDIGG T++RA
Sbjct: 115 PFRETIAKPGCSFADAIENIDIGGPTMVRA 144


>UniRef50_Q9F1T4 Cluster: Bifunctional purine biosynthesis protein
           purH [Includes: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]; n=57; Bacteria|Rep: Bifunctional
           purine biosynthesis protein purH [Includes:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)] - Streptococcus suis
          Length = 515

 Score = 79.8 bits (188), Expect = 7e-14
 Identities = 39/85 (45%), Positives = 55/85 (64%), Gaps = 1/85 (1%)
 Frame = +1

Query: 10  GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLS-DSDQE 186
           G ++I++GGT  +L  AG+T   + D+T  PEM+ GRVKTLHP +H G+LAR   DS  +
Sbjct: 26  GWEIISTGGTKVALDQAGVTTIAIDDVTGFPEMMDGRVKTLHPKIHGGLLARRDLDSHLQ 85

Query: 187 DMKRQKYEMISVVVCNLYPFVQTYL 261
                +  +I +VV NLYPF +T L
Sbjct: 86  AANDHEIGLIDLVVVNLYPFKETIL 110



 Score = 70.1 bits (164), Expect = 5e-11
 Identities = 36/67 (53%), Positives = 41/67 (61%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRS 511
           AKNH  VTVV DPADY  V+ EI E    +T+  TRQRLA K F HT+ YD  I+DYF  
Sbjct: 135 AKNHASVTVVVDPADYPTVLGEIAEQG--ETSYATRQRLAAKVFRHTAAYDALIADYFTK 192

Query: 512 NTRPGKP 532
                KP
Sbjct: 193 QVGEDKP 199



 Score = 36.3 bits (80), Expect = 0.81
 Identities = 16/30 (53%), Positives = 22/30 (73%)
 Frame = +3

Query: 240 PVRPDVSKPDVTVADAVENIDIGGVTLLRA 329
           P +  + +PDVT   AVENIDIGG ++LR+
Sbjct: 104 PFKETILRPDVTYDLAVENIDIGGPSMLRS 133


>UniRef50_A7BET6 Cluster: Putative uncharacterized protein; n=1;
           Actinomyces odontolyticus ATCC 17982|Rep: Putative
           uncharacterized protein - Actinomyces odontolyticus ATCC
           17982
          Length = 614

 Score = 79.4 bits (187), Expect = 9e-14
 Identities = 37/85 (43%), Positives = 56/85 (65%), Gaps = 1/85 (1%)
 Frame = +1

Query: 4   ECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILA-RLSDSD 180
           E G++++++G TA  +  AG+ V  V D+T  PE+L GRVKTLHP +H+GILA +   + 
Sbjct: 38  EAGVEIVSTGSTAARIAAAGVAVTPVDDVTGFPEVLEGRVKTLHPFIHSGILADQRKAAH 97

Query: 181 QEDMKRQKYEMISVVVCNLYPFVQT 255
           +E + +   +   +VVCNLYPF  T
Sbjct: 98  REQIAQLGIQAFDLVVCNLYPFQDT 122



 Score = 41.1 bits (92), Expect = 0.028
 Identities = 24/57 (42%), Positives = 31/57 (54%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDY 502
           AKNH  V VV  P  Y  V + +        TL  R+ LA +AF HT+ YDLAI+ +
Sbjct: 148 AKNHPSVAVVTSPERYADVAEAVAGEGF---TLEQRRVLAAEAFAHTATYDLAIAGW 201


>UniRef50_Q8XMK2 Cluster: Bifunctional purine biosynthesis protein
           purH [Includes: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]; n=14; Bacteria|Rep: Bifunctional
           purine biosynthesis protein purH [Includes:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)] - Clostridium perfringens
          Length = 501

 Score = 78.6 bits (185), Expect = 2e-13
 Identities = 38/81 (46%), Positives = 56/81 (69%), Gaps = 1/81 (1%)
 Frame = +1

Query: 13  LQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILA-RLSDSDQED 189
           +++I+SGGT + L+   + V+++S+IT  PEML GRVKTLHP VHAGILA R +    + 
Sbjct: 27  VEIISSGGTYKYLKENNIEVKEISEITDFPEMLDGRVKTLHPLVHAGILAIRDNKEHMKT 86

Query: 190 MKRQKYEMISVVVCNLYPFVQ 252
           ++ ++   I  VV NLYPF +
Sbjct: 87  LEEREINTIDYVVVNLYPFFE 107



 Score = 42.7 bits (96), Expect = 0.009
 Identities = 25/57 (43%), Positives = 33/57 (57%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDY 502
           AKN   V V+ D  DY+ V+ EIKEN  +  +   R+ LA K F   S YD AIS++
Sbjct: 134 AKNFKDVVVLSDKKDYEKVMNEIKEN--NCVSFKLRKTLAGKVFNLMSAYDAAISNF 188



 Score = 35.5 bits (78), Expect = 1.4
 Identities = 26/73 (35%), Positives = 36/73 (49%), Gaps = 4/73 (5%)
 Frame = +1

Query: 541 LRYGMNPHQKPAQVFTTRDSLPITT---LNG-APGFINLCDALNAWQLVKELKEALSLPA 708
           LRYG NPHQ  A   +T     + +   LNG A  + N+ D   AW++  E +E     A
Sbjct: 210 LRYGENPHQGAAYYSSTEFDGAMNSFEILNGKALSYNNIKDLDIAWKVACEFEET----A 265

Query: 709 AASFKHVSPAGAA 747
             + KH +P G A
Sbjct: 266 CCALKHNTPCGVA 278


>UniRef50_Q8F3W6 Cluster: Bifunctional purine biosynthesis protein
           purH [Includes: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]; n=6; Bacteria|Rep: Bifunctional
           purine biosynthesis protein purH [Includes:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)] - Leptospira interrogans
          Length = 511

 Score = 77.8 bits (183), Expect = 3e-13
 Identities = 36/83 (43%), Positives = 57/83 (68%), Gaps = 1/83 (1%)
 Frame = +1

Query: 10  GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSD-SDQE 186
           G+++I++GGT + L++ G+    + D T  PE+L GRVKTLHP VH G+L  +S+ + ++
Sbjct: 28  GVEIISTGGTLKLLKDNGIAAIAIDDYTGFPEILDGRVKTLHPKVHGGLLGVISNPAHKQ 87

Query: 187 DMKRQKYEMISVVVCNLYPFVQT 255
            M+  K   I +VV NLYPF++T
Sbjct: 88  KMEELKIPKIDLVVVNLYPFLKT 110



 Score = 37.9 bits (84), Expect = 0.26
 Identities = 21/58 (36%), Positives = 30/58 (51%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYF 505
           AKN+    V+ DP DY  +   I  +   +    +  R   KAF+HT+ YD AIS +F
Sbjct: 137 AKNYKHTLVLTDPNDYKKIQNLISSSGISEEISASYMR---KAFSHTAMYDAAISSWF 191



 Score = 37.1 bits (82), Expect = 0.46
 Identities = 15/30 (50%), Positives = 23/30 (76%)
 Frame = +3

Query: 240 PVRPDVSKPDVTVADAVENIDIGGVTLLRA 329
           P    VSKP+V + +A+ENIDIGG +++R+
Sbjct: 106 PFLKTVSKPEVQLEEAIENIDIGGPSMIRS 135


>UniRef50_Q9PNY2 Cluster: Bifunctional purine biosynthesis protein
           purH [Includes: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]; n=21; Epsilonproteobacteria|Rep:
           Bifunctional purine biosynthesis protein purH [Includes:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)] - Campylobacter jejuni
          Length = 510

 Score = 77.8 bits (183), Expect = 3e-13
 Identities = 36/83 (43%), Positives = 55/83 (66%), Gaps = 1/83 (1%)
 Frame = +1

Query: 10  GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQ-E 186
           G +++++GGT + L+  G+ V +VSD T++PE+  GRVKTLHP +H GIL + SD +  +
Sbjct: 24  GFEILSTGGTFKLLKENGIKVIEVSDFTKSPELFEGRVKTLHPKIHGGILHKRSDENHIK 83

Query: 187 DMKRQKYEMISVVVCNLYPFVQT 255
             K  +   I +V  NLYPF +T
Sbjct: 84  QAKENEILGIDLVCVNLYPFKKT 106



 Score = 51.2 bits (117), Expect = 3e-05
 Identities = 23/65 (35%), Positives = 39/65 (60%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRS 511
           AKN+  V V+CDP DY+ V++ +K+ ++ +     R  L +KA+ HT++YD  I++Y   
Sbjct: 132 AKNYKDVMVLCDPLDYEKVIETLKKGQNDE---NFRLNLMIKAYEHTANYDAYIANYMNE 188

Query: 512 NTRPG 526
               G
Sbjct: 189 RFNGG 193



 Score = 40.3 bits (90), Expect = 0.049
 Identities = 30/85 (35%), Positives = 35/85 (41%), Gaps = 1/85 (1%)
 Frame = +1

Query: 496 GLLPQQYSPGQAQLTLRYGMNPHQKPA-QVFTTRDSLPITTLNGAPGFINLCDALNAWQL 672
           G    ++  GQ     +YG NPHQK A   F    S     L G   F NL D   A  L
Sbjct: 193 GFGASKFIVGQKVFDTKYGENPHQKGALYEFDAFFSANFKALKGEASFNNLTDINAALNL 252

Query: 673 VKELKEALSLPAAASFKHVSPAGAA 747
                +A   PA A  KH +P G A
Sbjct: 253 ASSFDKA---PAIAIVKHGNPCGFA 274


>UniRef50_Q8G6B1 Cluster: Bifunctional purine biosynthesis protein
           purH [Includes: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]; n=89; Bacteria|Rep: Bifunctional
           purine biosynthesis protein purH [Includes:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)] - Bifidobacterium longum
          Length = 545

 Score = 77.8 bits (183), Expect = 3e-13
 Identities = 36/85 (42%), Positives = 56/85 (65%), Gaps = 1/85 (1%)
 Frame = +1

Query: 4   ECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQ 183
           + G +++++G TA+ L   G+ V +VSD+T  PE L GRVKTLHP +HAGILA +++ + 
Sbjct: 30  KAGTEVVSTGSTAKKLAELGVKVTEVSDVTGFPECLDGRVKTLHPYIHAGILADMTNPEH 89

Query: 184 -EDMKRQKYEMISVVVCNLYPFVQT 255
            + ++    +   +VV NLYPF  T
Sbjct: 90  AKQLEEFGIKPFDLVVVNLYPFADT 114



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 24/57 (42%), Positives = 33/57 (57%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDY 502
           AKNH  V +V DPADY  V   + +      +L  R+ LA KAF HT+ YD  I+++
Sbjct: 140 AKNHATVAIVTDPADYALVASRVADGTGF--SLDERKWLAAKAFAHTAAYDATINEW 194



 Score = 34.7 bits (76), Expect = 2.5
 Identities = 26/74 (35%), Positives = 34/74 (45%), Gaps = 4/74 (5%)
 Frame = +1

Query: 538 TLRYGMNPHQKPAQVFTTRDSLPIT---TLNGAP-GFINLCDALNAWQLVKELKEALSLP 705
           TLRYG N HQ+ A      +         L G P  + N  DA  AW+ V ++  A+   
Sbjct: 237 TLRYGENSHQQAALYIDPLNQTGFAHAEQLGGKPMSYNNYVDADAAWRTVWDMAPAI--- 293

Query: 706 AAASFKHVSPAGAA 747
           A A  KH +P G A
Sbjct: 294 AVAVVKHNNPCGLA 307


>UniRef50_Q6L122 Cluster: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase; n=4; Thermoplasmatales|Rep:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase - Picrophilus torridus
          Length = 494

 Score = 76.6 bits (180), Expect = 6e-13
 Identities = 35/79 (44%), Positives = 54/79 (68%)
 Frame = +1

Query: 25  ASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQEDMKRQK 204
           A+ GT + L ++G+  + +SDIT   ++L GRVKTLHPAV +GIL+R  +  + D+KR  
Sbjct: 26  ATPGTFKFLSDSGIKAKRISDITGFDDLLNGRVKTLHPAVFSGILSRRDEQSEADLKRYN 85

Query: 205 YEMISVVVCNLYPFVQTYL 261
           Y    +V+CNLY F ++Y+
Sbjct: 86  YFDFDIVICNLYNF-ESYI 103



 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 21/54 (38%), Positives = 35/54 (64%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAI 493
           AKN+  VTV   P DY+ ++K++++    + +L TR+ LAL+AF   + YD+ I
Sbjct: 126 AKNYQHVTVASSPEDYNIIIKDLRDG---EISLRTRETLALRAFARAAYYDMII 176


>UniRef50_Q7MUT5 Cluster: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase/IMP cyclohydrolase; n=24;
           Bacteria|Rep: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase/IMP cyclohydrolase - Porphyromonas
           gingivalis (Bacteroides gingivalis)
          Length = 508

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 35/83 (42%), Positives = 52/83 (62%), Gaps = 1/83 (1%)
 Frame = +1

Query: 10  GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLS-DSDQE 186
           G++ +++GGT   + + G   + V D+TR P MLGGRVKTLHP +  GILAR   +SD  
Sbjct: 32  GVEFVSTGGTHEFITSLGYACRAVDDLTRYPSMLGGRVKTLHPMIFGGILARRGHESDVR 91

Query: 187 DMKRQKYEMISVVVCNLYPFVQT 255
           ++      +I +V+ +LYPF  T
Sbjct: 92  EVGEYGLPLIDLVIVDLYPFEAT 114


>UniRef50_Q7VRP9 Cluster: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase, IMP cyclohydrolase and MGS-like
           domain; n=2; Candidatus Blochmannia|Rep:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase, IMP cyclohydrolase and MGS-like
           domain - Blochmannia floridanus
          Length = 549

 Score = 73.3 bits (172), Expect = 6e-12
 Identities = 36/82 (43%), Positives = 54/82 (65%)
 Frame = +1

Query: 1   SECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSD 180
           S  G++L+++ GTA  L NAGLTV  +SD T  PE++ G+VKTLH  + AGIL+R  + D
Sbjct: 28  SHLGIKLLSTEGTALILTNAGLTVNKISDYTNFPEIMNGQVKTLHHKICAGILSR-KNLD 86

Query: 181 QEDMKRQKYEMISVVVCNLYPF 246
           +  + +   + I +V+ N YPF
Sbjct: 87  ESIIHKYGIQPIDMVIVNFYPF 108



 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 32/88 (36%), Positives = 44/88 (50%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRS 511
           AKN+    ++ D  DYD ++ EI    H   +L TR  LA KAF +   YD  ISDYF+ 
Sbjct: 138 AKNYKNTVIIVDNNDYDNILNEIN-TLHGSISLNTRLNLAAKAFKYIKQYDTMISDYFQH 196

Query: 512 NTRPGKPN*P*DTV*THIRSRPRYSRPE 595
             +  +PN P  T+   I+       PE
Sbjct: 197 QLKL-QPNKPHHTIQKRIQPFNHSQLPE 223


>UniRef50_Q316G8 Cluster: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase; n=4; Desulfovibrionaceae|Rep:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase - Desulfovibrio desulfuricans (strain
           G20)
          Length = 252

 Score = 72.5 bits (170), Expect = 1e-11
 Identities = 35/80 (43%), Positives = 50/80 (62%), Gaps = 1/80 (1%)
 Frame = +1

Query: 10  GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQ-E 186
           G++L+++GGT R+L  AGL V  VS +T  PE++GGRVKTLHP +H GILA   + +   
Sbjct: 83  GVELVSTGGTQRTLTEAGLDVTPVSKVTGFPEIMGGRVKTLHPHIHGGILADKDNPEHLA 142

Query: 187 DMKRQKYEMISVVVCNLYPF 246
            +K        ++  NLY F
Sbjct: 143 TLKELGIRTFDLICVNLYNF 162



 Score = 53.6 bits (123), Expect = 5e-06
 Identities = 28/63 (44%), Positives = 39/63 (61%)
 Frame = +2

Query: 329 TAKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFR 508
           TAKN   + V+ DPADY A ++E+++N   +  L  RQ +A+K F  TS YD  I+DY  
Sbjct: 190 TAKNFHSMLVLPDPADYQAAMQEMRDN-DMRVGLAMRQAMAVKTFRATSAYDGMIADYLG 248

Query: 509 SNT 517
           S T
Sbjct: 249 SKT 251


>UniRef50_Q8A155 Cluster: Bifunctional purine biosynthesis protein
           purH [Includes: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]; n=5; Bacteroides|Rep: Bifunctional
           purine biosynthesis protein purH [Includes:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)] - Bacteroides thetaiotaomicron
          Length = 507

 Score = 72.5 bits (170), Expect = 1e-11
 Identities = 36/86 (41%), Positives = 56/86 (65%), Gaps = 2/86 (2%)
 Frame = +1

Query: 4   ECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQ 183
           E G++ +++GGT + + + G   + V D+T  P +LGGRVKTLHP +  GIL R  D +Q
Sbjct: 29  EEGVEFLSTGGTRQFIESLGYPCKAVEDLTTYPSILGGRVKTLHPKIFGGILCR-RDLEQ 87

Query: 184 EDMKRQKYEM--ISVVVCNLYPFVQT 255
           +  + +KYE+  I +V+ +LYPF  T
Sbjct: 88  DIQQIEKYEIPEIDLVIVDLYPFEAT 113



 Score = 35.1 bits (77), Expect = 1.9
 Identities = 20/58 (34%), Positives = 34/58 (58%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYF 505
           AKN++ V +V   A Y  ++  + E+    ++L  R+ +A +AF  +S YD AI +YF
Sbjct: 139 AKNYNDVIIVASQAQYKPLLDMLMEHGA-TSSLEERRWMAKEAFAVSSHYDSAIFNYF 195


>UniRef50_A7I7L2 Cluster: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase/IMP cyclohydrolase; n=1; Candidatus
           Methanoregula boonei 6A8|Rep:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase/IMP cyclohydrolase - Methanoregula
           boonei (strain 6A8)
          Length = 525

 Score = 69.7 bits (163), Expect = 7e-11
 Identities = 35/76 (46%), Positives = 46/76 (60%)
 Frame = +1

Query: 19  LIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQEDMKR 198
           +++SGGT  +L  AG+   +VS  T  PEM+ GRVKTLHP VH G+L R    D   M +
Sbjct: 58  IMSSGGTGTALAGAGIPFTEVSRYTGFPEMMDGRVKTLHPKVHGGLLGR-RQIDDAIMAK 116

Query: 199 QKYEMISVVVCNLYPF 246
                I ++V NLYPF
Sbjct: 117 YGINRIGLLVVNLYPF 132



 Score = 43.2 bits (97), Expect = 0.007
 Identities = 30/68 (44%), Positives = 36/68 (52%), Gaps = 4/68 (5%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRL--ALKAFTHTSDYDLAISDYF 505
           AKN   V VV DP+DY  VVK +  N          QRL  A KAF  T+ YD AIS++ 
Sbjct: 161 AKNFKDVAVVVDPSDYPEVVKTLSSN----VGFSHEQRLIFAKKAFARTAAYDAAISNHL 216

Query: 506 RS--NTRP 523
            +  NT P
Sbjct: 217 SNLDNTFP 224


>UniRef50_Q83GZ1 Cluster: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase; n=2; Tropheryma whipplei|Rep:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase - Tropheryma whipplei (strain Twist)
           (Whipple's bacillus)
          Length = 542

 Score = 68.9 bits (161), Expect = 1e-10
 Identities = 32/81 (39%), Positives = 52/81 (64%), Gaps = 1/81 (1%)
 Frame = +1

Query: 13  LQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILA-RLSDSDQED 189
           ++++++G TA  +R   + V+DVS++T   E+L GRVKTLHP +HA ILA   S   +  
Sbjct: 32  VKIVSTGSTAEFIRGVSIPVRDVSEVTGVGELLDGRVKTLHPKIHAPILADTTSQMHRAQ 91

Query: 190 MKRQKYEMISVVVCNLYPFVQ 252
           +++   +   +VV NLYPF +
Sbjct: 92  LQQLGVDAFDLVVVNLYPFFE 112



 Score = 52.0 bits (119), Expect = 2e-05
 Identities = 25/55 (45%), Positives = 36/55 (65%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAIS 496
           AKNH RV V+ DP+DY  V+  ++     +     R +LA+KA++HTS+YDL IS
Sbjct: 140 AKNHTRVVVIVDPSDYIHVINSLERGAPSRL----RHQLAIKAYSHTSEYDLHIS 190


>UniRef50_A1G3C3 Cluster: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase; n=1; Salinispora arenicola
           CNS205|Rep: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase - Salinispora arenicola CNS205
          Length = 190

 Score = 67.3 bits (157), Expect = 4e-10
 Identities = 33/77 (42%), Positives = 49/77 (63%)
 Frame = +1

Query: 10  GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQED 189
           G  ++A+ GT R LR+ G+TV  VSD+   P +LGGRVKTL  ++  GILAR   +D+ +
Sbjct: 24  GWDVVATEGTRRLLRDHGVTVGAVSDLAGVPTLLGGRVKTLTVSLMGGILARDEPADRAE 83

Query: 190 MKRQKYEMISVVVCNLY 240
           ++R     + +V CN Y
Sbjct: 84  VERHGLTRVHLVCCNYY 100


>UniRef50_A7PK27 Cluster: Chromosome chr15 scaffold_19, whole genome
           shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
           chr15 scaffold_19, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 227

 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 31/80 (38%), Positives = 43/80 (53%), Gaps = 1/80 (1%)
 Frame = +1

Query: 10  GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDS-DQE 186
           G ++++ GGT  +L NA ++   V  +T  P++L G VKTLHP +  GIL R       E
Sbjct: 45  GYRIVSFGGTTLALENAWVSTTKVEQLTCFPKILDGHVKTLHPNIQGGILPRRDQKHHME 104

Query: 187 DMKRQKYEMISVVVCNLYPF 246
            +         VVV NLYPF
Sbjct: 105 ALNEHGIGTFDVVVVNLYPF 124


>UniRef50_Q8D244 Cluster: Bifunctional purine biosynthesis protein
           purH [Includes: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]; n=2; Gammaproteobacteria|Rep:
           Bifunctional purine biosynthesis protein purH [Includes:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)] - Wigglesworthia glossinidia
           brevipalpis
          Length = 529

 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 29/78 (37%), Positives = 46/78 (58%)
 Frame = +1

Query: 13  LQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQEDM 192
           ++LI + GT + L   G+    VS+    PE++ GRVKTLHP +H GIL+  ++ +  + 
Sbjct: 33  VKLITTSGTYKYLLEKGIFSTSVSEYINHPEIINGRVKTLHPKIHGGILS--NNKNINEN 90

Query: 193 KRQKYEMISVVVCNLYPF 246
           K    + I +V+ N YPF
Sbjct: 91  KNLNIKKIDMVITNFYPF 108


>UniRef50_Q89B23 Cluster: Bifunctional purine biosynthesis protein
           purH [Includes: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]; n=2; Buchnera aphidicola (Baizongia
           pistaciae)|Rep: Bifunctional purine biosynthesis protein
           purH [Includes: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)] - Buchnera aphidicola subsp.
           Baizongia pistaciae
          Length = 529

 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 27/78 (34%), Positives = 49/78 (62%)
 Frame = +1

Query: 13  LQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQEDM 192
           ++L A+ GTA  L+   +   D+++ T  PE++ GR+KTLH  ++A ILA+    D++ +
Sbjct: 32  IKLFATKGTANFLKKNNIYATDITNYTNFPEIMNGRIKTLHHKIYASILAQ-PKHDKKTI 90

Query: 193 KRQKYEMISVVVCNLYPF 246
           ++    ++ +VV N YPF
Sbjct: 91  EKYNIILMDIVVINFYPF 108



 Score = 36.7 bits (81), Expect = 0.61
 Identities = 21/63 (33%), Positives = 31/63 (49%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRS 511
           AKN+  V VV  P  Y ++V E+  N +  +   T+ + A  AF HT +YD  I  Y   
Sbjct: 138 AKNYKNVLVVTQPNLYQSIVNEMNLNNNIISET-TKLKFATIAFKHTMNYDNNIYQYLSK 196

Query: 512 NTR 520
             +
Sbjct: 197 KNK 199


>UniRef50_A1IEQ8 Cluster: IMP cyclohydrolase; n=1; Candidatus
           Desulfococcus oleovorans Hxd3|Rep: IMP cyclohydrolase -
           Candidatus Desulfococcus oleovorans Hxd3
          Length = 225

 Score = 59.3 bits (137), Expect = 1e-07
 Identities = 31/63 (49%), Positives = 40/63 (63%)
 Frame = +2

Query: 329 TAKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFR 508
           +AKN  RV  V DPADY+ V  E+ E++    +L TR  LA KAF HT+ YD AI+DY +
Sbjct: 154 SAKNFLRVASVVDPADYNTVADEM-EHRQGALSLDTRFELAQKAFDHTAAYDRAIADYLK 212

Query: 509 SNT 517
             T
Sbjct: 213 KQT 215



 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 33/87 (37%), Positives = 46/87 (52%), Gaps = 6/87 (6%)
 Frame = +1

Query: 13  LQLIASGGTARSLRN-----AGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARL-SD 174
           + + ++GGT + +       A   +  VSD T  PE  GG VKTL   ++ G+L    ++
Sbjct: 42  VHIFSTGGTYQKIYEIFGSAAKSVLTQVSDYTGQPETQGGLVKTLDFKIYLGLLTETYNE 101

Query: 175 SDQEDMKRQKYEMISVVVCNLYPFVQT 255
           S   DMKR     I +VV NLYPF QT
Sbjct: 102 SHARDMKRTGAVAIDMVVVNLYPFSQT 128


>UniRef50_Q6MIZ2 Cluster: IMP cyclohydrolase; n=1; Bdellovibrio
           bacteriovorus|Rep: IMP cyclohydrolase - Bdellovibrio
           bacteriovorus
          Length = 507

 Score = 56.8 bits (131), Expect = 5e-07
 Identities = 33/82 (40%), Positives = 46/82 (56%), Gaps = 1/82 (1%)
 Frame = +1

Query: 13  LQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSD-SDQED 189
           ++LIASGGTA++L  AGL V  V  ++   E   GR+KT+   + + +L R  D +D   
Sbjct: 29  VELIASGGTAKALTEAGLKVTAVETLSGKGEAFNGRMKTISFEIASSLLFRRQDENDVRQ 88

Query: 190 MKRQKYEMISVVVCNLYPFVQT 255
                 E I +VV NLYPF  T
Sbjct: 89  AAELGIEPIDLVVVNLYPFHAT 110



 Score = 50.4 bits (115), Expect = 5e-05
 Identities = 25/62 (40%), Positives = 36/62 (58%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRS 511
           AKN   VTV+CDP+ Y   +KE   N +  TT   RQ+ A   +T T+ YD+AI+ +   
Sbjct: 136 AKNFHSVTVLCDPSQYSEFLKEFNGN-NGSTTWEFRQKCAAAVYTMTAFYDMAIAGFLTQ 194

Query: 512 NT 517
           N+
Sbjct: 195 NS 196


>UniRef50_A4MAE3 Cluster: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase; n=1; Petrotoga mobilis SJ95|Rep:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase - Petrotoga mobilis SJ95
          Length = 489

 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 29/80 (36%), Positives = 47/80 (58%), Gaps = 1/80 (1%)
 Frame = +1

Query: 10  GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSD-SDQE 186
           G+++I + GT + L+  G+    ++D    PE+LGGRVK++ P +  GILA+ +D   +E
Sbjct: 27  GVEIICTEGTNKYLQEKGIPTVKMADYIGFPEILGGRVKSIDPKLAGGILAKSNDKKHEE 86

Query: 187 DMKRQKYEMISVVVCNLYPF 246
           DM     + I +VV N   F
Sbjct: 87  DMINYNIKRIDMVVGNFPTF 106



 Score = 41.5 bits (93), Expect = 0.021
 Identities = 22/58 (37%), Positives = 31/58 (53%)
 Frame = +2

Query: 332 AKNHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYF 505
           AKN+  V  + DP DY  V+  +++       L  R++LALK F  TS YD +I   F
Sbjct: 135 AKNYKDVVALADPKDYQTVIDNLEDCG--DVPLQLRRKLALKVFFSTSKYDASIHKIF 190


>UniRef50_Q9X0X6 Cluster: Bifunctional purine biosynthesis protein
           purH [Includes: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)]; n=4; Thermotogaceae|Rep:
           Bifunctional purine biosynthesis protein purH [Includes:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (EC 2.1.2.3) (AICAR transformylase);
           IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP
           synthetase) (ATIC)] - Thermotoga maritima
          Length = 452

 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 27/52 (51%), Positives = 35/52 (67%)
 Frame = +1

Query: 4   ECGLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGIL 159
           E G ++ AS GTA+ L++ G+   DVS IT    +LGG VKTLHP + AGIL
Sbjct: 23  EKGWEIWASSGTAKFLKSNGIEANDVSTITGFENLLGGLVKTLHPEIFAGIL 74



 Score = 41.5 bits (93), Expect = 0.021
 Identities = 29/71 (40%), Positives = 35/71 (49%)
 Frame = +1

Query: 535 LTLRYGMNPHQKPAQVFTTRDSLPITTLNGAPGFINLCDALNAWQLVKELKEALSLPAAA 714
           L LRYG NPH+K A V+  + +  I        F N+ DA NAW + K L        A 
Sbjct: 167 LQLRYGENPHEK-AFVY-GKPAFEILHEGKTISFNNILDAENAWFMAKNLPRM----GAV 220

Query: 715 SFKHVSPAGAA 747
             KH SP GAA
Sbjct: 221 VVKHQSPCGAA 231


>UniRef50_A5B1A5 Cluster: DNA-directed RNA polymerase; n=1; Vitis
           vinifera|Rep: DNA-directed RNA polymerase - Vitis
           vinifera (Grape)
          Length = 202

 Score = 50.0 bits (114), Expect = 6e-05
 Identities = 22/52 (42%), Positives = 33/52 (63%)
 Frame = +1

Query: 10  GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILAR 165
           G ++++ GGT  +L NA ++   V  +T  P++L G VKTLHP +  GIL R
Sbjct: 45  GYRIVSFGGTTLALENAWVSTTKVEQLTCFPKILDGHVKTLHPNIQGGILPR 96


>UniRef50_A5B3D8 Cluster: DNA-directed RNA polymerase; n=1; Vitis
           vinifera|Rep: DNA-directed RNA polymerase - Vitis
           vinifera (Grape)
          Length = 153

 Score = 46.4 bits (105), Expect = 8e-04
 Identities = 24/48 (50%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
 Frame = +1

Query: 106 MLGGRVKTLHPAVHAGILARLSDS-DQEDMKRQKYEMISVVVCNLYPF 246
           ML G VKTLHP +H GILAR       E +         VVV NLYPF
Sbjct: 1   MLDGHVKTLHPNIHGGILARRDQKHHMEALNEHGIGTFDVVVVNLYPF 48


>UniRef50_A6PRZ4 Cluster: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase; n=1; Victivallis vadensis ATCC
           BAA-548|Rep: Phosphoribosylaminoimidazolecarboxamide
           formyltransferase - Victivallis vadensis ATCC BAA-548
          Length = 372

 Score = 40.3 bits (90), Expect = 0.049
 Identities = 35/98 (35%), Positives = 44/98 (44%), Gaps = 11/98 (11%)
 Frame = +1

Query: 487 RHIGLLPQQYSPGQAQLT----LRYGMNPHQ-----KPAQVFTTRDSLPITTLNGAPGF- 636
           +H+G  P + + G  +      LRYG NPHQ     KPA        + I   NG  G  
Sbjct: 13  KHVGDFPAEITIGSRRYVKVDDLRYGTNPHQAASYYKPADEACVIGDMKILK-NGKSGLS 71

Query: 637 -INLCDALNAWQLVKELKEALSLPAAASFKHVSPAGAA 747
             NL D   A  +VK        PA A  KHV+P+GAA
Sbjct: 72  QTNLEDISYALNIVK----FFDTPACAVMKHVNPSGAA 105


>UniRef50_A6DLC7 Cluster: IMP cyclohydrolase; n=1; Lentisphaera
           araneosa HTCC2155|Rep: IMP cyclohydrolase - Lentisphaera
           araneosa HTCC2155
          Length = 369

 Score = 37.9 bits (84), Expect = 0.26
 Identities = 31/76 (40%), Positives = 37/76 (48%), Gaps = 7/76 (9%)
 Frame = +1

Query: 541 LRYGMNPHQ-----KPAQVFTTRDSLPITTLNGAPGF--INLCDALNAWQLVKELKEALS 699
           LRYG NPHQ     KPA + +    L +   NG  G    NL D   A  +VK   E   
Sbjct: 36  LRYGTNPHQTAAFYKPAGLESPIGDLKVLK-NGKSGLSQTNLEDISYALNIVKFFDE--- 91

Query: 700 LPAAASFKHVSPAGAA 747
            P  A  KHV+P+GAA
Sbjct: 92  -PTCAVMKHVNPSGAA 106


>UniRef50_Q0W4V4 Cluster: Predicted ABC-type transport system,
           permease component; n=2; uncultured methanogenic
           archaeon RC-I|Rep: Predicted ABC-type transport system,
           permease component - Uncultured methanogenic archaeon
           RC-I
          Length = 408

 Score = 36.7 bits (81), Expect = 0.61
 Identities = 28/83 (33%), Positives = 37/83 (44%), Gaps = 1/83 (1%)
 Frame = +1

Query: 457 GVHSYFG-L*PRHIGLLPQQYSPGQAQLTLRYGMNPHQKPAQVFTTRDSLPITTLNGAPG 633
           GV + FG L    I LLPQ        + + YG+    KP   FT RD   I T+   PG
Sbjct: 48  GVSAEFGDLDLNQIILLPQSLEDQSGGMGMSYGIAQTSKPPARFTDRD---IQTILSTPG 104

Query: 634 FINLCDALNAWQLVKELKEALSL 702
            + +   + A+  V  L E  SL
Sbjct: 105 VVEVNPKIEAYGTVSYLSENRSL 127


>UniRef50_A1FWI7 Cluster: Putative uncharacterized protein
           precursor; n=1; Stenotrophomonas maltophilia R551-3|Rep:
           Putative uncharacterized protein precursor -
           Stenotrophomonas maltophilia R551-3
          Length = 589

 Score = 35.5 bits (78), Expect = 1.4
 Identities = 18/50 (36%), Positives = 26/50 (52%)
 Frame = -3

Query: 150 SMYRWM*SFHPTSEHLRCSRDVRHILNCEAGVPKRPGGTATGNQLQATFR 1
           +M+  +    P   H R + DV H+L+ +A +  R GG A G QL A  R
Sbjct: 480 AMHHRVQGLDPAVHHFREAGDVGHVLHGQARIADRLGGAAGGQQLHAACR 529


>UniRef50_Q08W60 Cluster: Putative uncharacterized protein; n=1;
           Stigmatella aurantiaca DW4/3-1|Rep: Putative
           uncharacterized protein - Stigmatella aurantiaca DW4/3-1
          Length = 611

 Score = 35.1 bits (77), Expect = 1.9
 Identities = 20/66 (30%), Positives = 31/66 (46%)
 Frame = +3

Query: 183 GRHETSEVRDDKRGGL*PVPVRPDVSKPDVTVADAVENIDIGGVTLLRAQPRTTTGSPSS 362
           G  ETSE+R++   G    P R      ++     VE + +GG   L+A P  TT + ++
Sbjct: 239 GHSETSELREESHDGGNIPPSRQPTRLLELAGGQLVEAVHMGGRRSLQAAPTATTATTTT 298

Query: 363 VTRPTT 380
            T   T
Sbjct: 299 TTTTAT 304


>UniRef50_Q9HS43 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           formyltransferase; n=5; Halobacteriaceae|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide
           formyltransferase - Halobacterium salinarium
           (Halobacterium halobium)
          Length = 595

 Score = 35.1 bits (77), Expect = 1.9
 Identities = 29/76 (38%), Positives = 34/76 (44%), Gaps = 7/76 (9%)
 Frame = +1

Query: 541 LRYGMNPHQKPA----QVFTTRDSLPITTLNG---APGFINLCDALNAWQLVKELKEALS 699
           LRYG NPHQ  A            +    LN    A  + N  DA  A  LV+E  +   
Sbjct: 287 LRYGENPHQDAAVYRDNTHAAASVVHADQLNPDAKALSYNNYNDADAALALVREFDDG-- 344

Query: 700 LPAAASFKHVSPAGAA 747
            PAAA  KH +PAG A
Sbjct: 345 -PAAAVIKHTNPAGCA 359


>UniRef50_Q4P5L9 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 567

 Score = 34.3 bits (75), Expect = 3.3
 Identities = 17/36 (47%), Positives = 24/36 (66%), Gaps = 1/36 (2%)
 Frame = -1

Query: 701 RLSASFSSLTSCQAFSASHRLIN-PGAPFSVVIGKL 597
           RL   F S++S +AFS SHR +N P +PF+V +  L
Sbjct: 43  RLLPGFRSVSSARAFSTSHRRLNTPKSPFAVFVETL 78


>UniRef50_Q6AGB7 Cluster: Flagellar hook-associated protein 3; n=1;
           Leifsonia xyli subsp. xyli|Rep: Flagellar
           hook-associated protein 3 - Leifsonia xyli subsp. xyli
          Length = 290

 Score = 33.9 bits (74), Expect = 4.3
 Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
 Frame = +2

Query: 353 TVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAIS-DYFRSNTRPG 526
           T    PA+ D++VK I++ K +   L   Q L    F  TSD D A     +  N  PG
Sbjct: 102 TGTSSPANQDSIVKSIEQLKQNLLALANTQYLGRSVFAGTSDADTAFDVKSYAFNGTPG 160


>UniRef50_Q337Q0 Cluster: Expressed protein; n=1; Oryza sativa
           (japonica cultivar-group)|Rep: Expressed protein - Oryza
           sativa subsp. japonica (Rice)
          Length = 170

 Score = 33.5 bits (73), Expect = 5.7
 Identities = 21/56 (37%), Positives = 29/56 (51%), Gaps = 1/56 (1%)
 Frame = -2

Query: 382 IVVGRVTD-DGDPVVVLGCARRRVTPPMSMFSTASATVTSGLDTSGRTGTGYRPPR 218
           + VG+  D DGDPV+ LG AR+     M + +     V  G D +   G+G R PR
Sbjct: 20  VAVGQTVDLDGDPVLALGMARQVAVEHMLVEAEEQEVVERGHDMA---GSGIRYPR 72


>UniRef50_Q54WL3 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 276

 Score = 33.5 bits (73), Expect = 5.7
 Identities = 13/66 (19%), Positives = 33/66 (50%)
 Frame = +2

Query: 338 NHDRVTVVCDPADYDAVVKEIKENKHHQTTLGTRQRLALKAFTHTSDYDLAISDYFRSNT 517
           N++ +++ CD   +  +++E+K+ +    T     +    + ++ ++Y+L I D F +N 
Sbjct: 46  NNNNISINCDNTQFQTILRELKKREFQNKTRKPINKKLNSSNSNNNNYNLKIEDNFINNN 105

Query: 518 RPGKPN 535
                N
Sbjct: 106 NNNNKN 111


>UniRef50_Q4T8W0 Cluster: Chromosome undetermined SCAF7713, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF7713,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 1076

 Score = 33.1 bits (72), Expect = 7.5
 Identities = 16/42 (38%), Positives = 20/42 (47%)
 Frame = +3

Query: 474 RTMTSPYRTTSAAILARASPTDLKIRYEPTSEAGPGIHDQRQ 599
           R    P R  SA  ++ A P  +  R  P  + GPG  DQRQ
Sbjct: 583 RWRPGPAREASATSVSSAGPAGMDQRQVPGGDRGPGCEDQRQ 624


>UniRef50_Q0ICG1 Cluster: Lipase/esterase family protein; n=1;
           Synechococcus sp. CC9311|Rep: Lipase/esterase family
           protein - Synechococcus sp. (strain CC9311)
          Length = 290

 Score = 33.1 bits (72), Expect = 7.5
 Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 2/77 (2%)
 Frame = -2

Query: 580 PGPASDVG-SYRILRSVGLARASIAAEVVRYGEVIVRSMSERLQG*SLPCAQSRLMMFVL 404
           P P  D   +YR L + G    +IA   +  G  +V  +  R Q  SLP     L+M  +
Sbjct: 89  PAPLDDAEEAYRWLLAQGYRSEAIAVAGISAGATLVTQLLHRCQSKSLPMPSLALVMAGV 148

Query: 403 FDF-FDYSIVVGRVTDD 356
            DF +    VV   +DD
Sbjct: 149 MDFSYGRESVVFNASDD 165


>UniRef50_Q8LNV5 Cluster: Putative uncharacterized protein
           OSJNBa0012L23.53; n=2; Oryza sativa|Rep: Putative
           uncharacterized protein OSJNBa0012L23.53 - Oryza sativa
           subsp. japonica (Rice)
          Length = 262

 Score = 33.1 bits (72), Expect = 7.5
 Identities = 16/48 (33%), Positives = 25/48 (52%)
 Frame = +3

Query: 30  WRYRQVASERRPHSSRCVGHHESTGDARRSGENFTSSGTCWDLSSIIR 173
           WRY+ VA   R  +S C G  + +      GE +  +G C D++ I+R
Sbjct: 121 WRYKGVA---RQSASMCCGQLDHSSGMHDDGEVWLRAGPCSDIAGIVR 165


>UniRef50_Q5FJY6 Cluster: Carbamoyl-phosphate synthase large subunit;
            n=5; Lactobacillus|Rep: Carbamoyl-phosphate synthase
            large subunit - Lactobacillus acidophilus
          Length = 1061

 Score = 32.7 bits (71), Expect = 9.9
 Identities = 20/63 (31%), Positives = 30/63 (47%)
 Frame = +1

Query: 10   GLQLIASGGTARSLRNAGLTVQDVSDITRAPEMLGGRVKTLHPAVHAGILARLSDSDQED 189
            G +L+A+ GTA     AG+T   V  +   P  L  +++  H  V    +  LSD+  ED
Sbjct: 964  GFKLVATEGTANIFAEAGITTGIVEKVHNNPRNLLEKIRQ-HKIVMVVNITNLSDAASED 1022

Query: 190  MKR 198
              R
Sbjct: 1023 ALR 1025


>UniRef50_Q0SCZ3 Cluster: Fructuronate reductase; n=1; Rhodococcus
           sp. RHA1|Rep: Fructuronate reductase - Rhodococcus sp.
           (strain RHA1)
          Length = 511

 Score = 32.7 bits (71), Expect = 9.9
 Identities = 19/50 (38%), Positives = 29/50 (58%), Gaps = 1/50 (2%)
 Frame = +2

Query: 374 DYDAVVKEIKENKHHQTTLGTRQR-LALKAFTHTSDYDLAISDYFRSNTR 520
           D DAV ++++E +  +TT+G   R LAL+A TH +   +   D   SN R
Sbjct: 142 DSDAVRRDLREVRTPRTTIGQIARGLALRASTHAAPVTILSCDNLLSNGR 191


>UniRef50_A3X0C9 Cluster: Putative uncharacterized protein; n=1;
           Nitrobacter sp. Nb-311A|Rep: Putative uncharacterized
           protein - Nitrobacter sp. Nb-311A
          Length = 242

 Score = 32.7 bits (71), Expect = 9.9
 Identities = 17/54 (31%), Positives = 26/54 (48%)
 Frame = +3

Query: 543 KIRYEPTSEAGPGIHDQRQLADHDTERCAWIYQPVRRAERLAARQGAEGSAEPP 704
           K++  P  EA PG  D+  +AD +  R +      R   R+ A +G +  A PP
Sbjct: 60  KVKQTPLPEAKPGAPDRITIADGEFGRESANLAAARERARIQASEGDDNEAAPP 113


>UniRef50_Q9AXF7 Cluster: RNA stability factor MCA1; n=1;
           Chlamydomonas reinhardtii|Rep: RNA stability factor MCA1
           - Chlamydomonas reinhardtii
          Length = 1068

 Score = 32.7 bits (71), Expect = 9.9
 Identities = 28/100 (28%), Positives = 40/100 (40%), Gaps = 3/100 (3%)
 Frame = +1

Query: 388 SQRNQREQTSSDDFGHKAEISPEGVHSYF---GL*PRHIGLLPQQYSPGQAQLTLRYGMN 558
           S RN R Q  S  +G  +   P  VH+ +   G        L QQ S   +  + R  + 
Sbjct: 150 SGRNGRPQGPSGRYGSSSASGPAPVHASYNNSGAPSSSPNALQQQQSQSGSADSRRCDLG 209

Query: 559 PHQKPAQVFTTRDSLPITTLNGAPGFINLCDALNAWQLVK 678
               PAQ+   RD     +L    G  + C  L+ W+L K
Sbjct: 210 DTGLPAQLLALRDPACPVSLPPPTGLPSSCLPLDNWKLDK 249


>UniRef50_Q5C3G2 Cluster: SJCHGC02321 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC02321 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 286

 Score = 32.7 bits (71), Expect = 9.9
 Identities = 14/26 (53%), Positives = 18/26 (69%)
 Frame = -2

Query: 406 LFDFFDYSIVVGRVTDDGDPVVVLGC 329
           L DF  YS+++GR T DGD V V+ C
Sbjct: 204 LGDFVFYSLLIGRATLDGDAVTVVTC 229


>UniRef50_Q6CDD1 Cluster: Similarities with DEHA0F12342g
           Debaryomyces hansenii; n=1; Yarrowia lipolytica|Rep:
           Similarities with DEHA0F12342g Debaryomyces hansenii -
           Yarrowia lipolytica (Candida lipolytica)
          Length = 872

 Score = 32.7 bits (71), Expect = 9.9
 Identities = 25/76 (32%), Positives = 34/76 (44%)
 Frame = +3

Query: 135 SSGTCWDLSSIIRL*PGRHETSEVRDDKRGGL*PVPVRPDVSKPDVTVADAVENIDIGGV 314
           SSGT +  SS+     GR+  S VR    GG   +     V    ++ A A+  +  GG+
Sbjct: 639 SSGTSFGYSSMTEFSFGRYGNSPVRGGGTGGSNALSA---VGSAALSTAAALSPVRNGGL 695

Query: 315 TLLRAQPRTTTGSPSS 362
           TL    P TT   P S
Sbjct: 696 TLAPLTPATTLAPPVS 711


>UniRef50_Q6C2W2 Cluster: Similarity; n=1; Yarrowia lipolytica|Rep:
           Similarity - Yarrowia lipolytica (Candida lipolytica)
          Length = 337

 Score = 32.7 bits (71), Expect = 9.9
 Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
 Frame = -2

Query: 235 GYRPPRLSSRTSDVSCLPGQS-RIIELRSQHVPLDVKFSPDLRA 107
           GY    ++     + CL G S  I +    + PLDV F+PDLR+
Sbjct: 217 GYISAAVNVANGQIFCLLGHSLAICDFAGNYTPLDVHFNPDLRS 260


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 744,042,977
Number of Sequences: 1657284
Number of extensions: 15277128
Number of successful extensions: 54112
Number of sequences better than 10.0: 73
Number of HSP's better than 10.0 without gapping: 51139
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 54016
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 61734884250
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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