Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= NV021216
(688 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q7PV64 Cluster: ENSANGP00000020137; n=5; Coelomata|Rep:... 165 7e-40
UniRef50_A2AAH7 Cluster: Growth factor receptor bound protein 2;... 117 3e-25
UniRef50_P62993 Cluster: Growth factor receptor-bound protein 2;... 117 3e-25
UniRef50_Q13588 Cluster: GRB2-related adapter protein; n=21; Bil... 113 3e-24
UniRef50_UPI00015A7910 Cluster: hypothetical protein LOC553596; ... 103 3e-21
UniRef50_Q4V9Q1 Cluster: Zgc:109892; n=11; Euteleostomi|Rep: Zgc... 101 1e-20
UniRef50_Q4T2Z8 Cluster: Chromosome 18 SCAF10147, whole genome s... 90 4e-17
UniRef50_Q4SAX0 Cluster: Chromosome 3 SCAF14679, whole genome sh... 90 4e-17
UniRef50_Q6PE32 Cluster: Zgc:65942; n=2; Danio rerio|Rep: Zgc:65... 87 3e-16
UniRef50_UPI00015A79D6 Cluster: hypothetical protein LOC550452; ... 87 4e-16
UniRef50_Q567F1 Cluster: Zgc:112091; n=2; Euteleostomi|Rep: Zgc:... 87 4e-16
UniRef50_UPI0000E478D2 Cluster: PREDICTED: similar to SH2/SH3 ad... 86 7e-16
UniRef50_O75791 Cluster: GRB2-related adapter protein 2; n=22; A... 86 7e-16
UniRef50_Q86F73 Cluster: Clone ZZD1053 mRNA sequence; n=1; Schis... 82 1e-14
UniRef50_Q5DBN4 Cluster: SJCHGC05332 protein; n=1; Schistosoma j... 79 1e-13
UniRef50_A2AAI0 Cluster: Growth factor receptor bound protein 2;... 78 2e-13
UniRef50_Q5BYR6 Cluster: SJCHGC04559 protein; n=1; Schistosoma j... 75 1e-12
UniRef50_P41240 Cluster: Tyrosine-protein kinase CSK; n=21; Deut... 75 2e-12
UniRef50_O77132 Cluster: Non-receptor protein-tyrosine kinase CS... 74 4e-12
UniRef50_P42686 Cluster: Tyrosine-protein kinase isoform SRK1; n... 73 5e-12
UniRef50_P62993-2 Cluster: Isoform GRB3; n=9; Deuterostomia|Rep:... 73 7e-12
UniRef50_Q9Y1Z0 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 55 8e-12
UniRef50_A7T2F6 Cluster: Predicted protein; n=2; Eumetazoa|Rep: ... 72 2e-11
UniRef50_A2RQD7 Cluster: Bcr-abl1 e19a2 chimeric protein; n=2; H... 72 2e-11
UniRef50_P00522 Cluster: Tyrosine-protein kinase Abl; n=5; Eumet... 72 2e-11
UniRef50_A2RQD6 Cluster: Bcr-abl1 e6a2 chimeric protein; n=10; E... 71 2e-11
UniRef50_P10447 Cluster: Tyrosine-protein kinase transforming pr... 71 2e-11
UniRef50_P42684 Cluster: Tyrosine-protein kinase ABL2; n=38; Eut... 71 2e-11
UniRef50_P00519 Cluster: Proto-oncogene tyrosine-protein kinase ... 71 2e-11
UniRef50_UPI00015B4B0F Cluster: PREDICTED: similar to proto-onco... 70 5e-11
UniRef50_A2RQD3 Cluster: Bcr-abl1 e13a3 chimeric protein; n=21; ... 70 6e-11
UniRef50_UPI0000519AF4 Cluster: PREDICTED: similar to Abl tyrosi... 69 8e-11
UniRef50_UPI000058445F Cluster: PREDICTED: similar to SH2/SH3 ad... 67 3e-10
UniRef50_Q4S516 Cluster: Chromosome 6 SCAF14737, whole genome sh... 55 5e-10
UniRef50_Q66I04 Cluster: Zgc:92124; n=1; Danio rerio|Rep: Zgc:92... 66 1e-09
UniRef50_Q4RNX3 Cluster: Chromosome 10 SCAF15009, whole genome s... 64 4e-09
UniRef50_UPI0000E248CE Cluster: PREDICTED: GRB2-related adaptor ... 62 9e-09
UniRef50_Q6R1Y3 Cluster: Src family kinase; n=6; Fungi/Metazoa g... 62 9e-09
UniRef50_P07947 Cluster: Proto-oncogene tyrosine-protein kinase ... 60 5e-08
UniRef50_Q4RL31 Cluster: Chromosome undetermined SCAF15024, whol... 58 2e-07
UniRef50_Q70DV1 Cluster: Src tyrosine kinase; n=1; Schistosoma m... 58 2e-07
UniRef50_A2AQ87 Cluster: Novel protein (Possible orthologue of h... 58 3e-07
UniRef50_Q95PW9 Cluster: Temporarily assigned gene name protein ... 58 3e-07
UniRef50_Q7M4L6 Cluster: Shb-like adapter protein, Shf; n=21; Am... 58 3e-07
UniRef50_Q573B4 Cluster: Proto-oncogene tyrosine-protein kinase ... 58 3e-07
UniRef50_UPI0000D9EE2E Cluster: PREDICTED: similar to src homolo... 57 4e-07
UniRef50_Q4S9J7 Cluster: Chromosome undetermined SCAF14696, whol... 57 5e-07
UniRef50_Q5BWZ4 Cluster: SJCHGC04657 protein; n=1; Schistosoma j... 57 5e-07
UniRef50_A7SE08 Cluster: Predicted protein; n=1; Nematostella ve... 57 5e-07
UniRef50_Q96IW2 Cluster: SH2 domain-containing adapter protein D... 56 6e-07
UniRef50_UPI0000F1FB23 Cluster: PREDICTED: similar to tyrosine p... 56 8e-07
UniRef50_Q7QGU0 Cluster: ENSANGP00000018199; n=1; Anopheles gamb... 56 8e-07
UniRef50_Q17BH3 Cluster: Putative uncharacterized protein; n=1; ... 56 8e-07
UniRef50_P03949 Cluster: Tyrosine-protein kinase abl-1; n=5; Cae... 56 8e-07
UniRef50_Q0PDJ5 Cluster: Protein tyrosine kinase CSK; n=1; Monos... 55 1e-06
UniRef50_Q8BZ27 Cluster: Adult female vagina cDNA, RIKEN full-le... 55 2e-06
UniRef50_O43639 Cluster: Cytoplasmic protein NCK2; n=54; Euteleo... 55 2e-06
UniRef50_P42685 Cluster: Tyrosine-protein kinase FRK; n=27; Fung... 54 2e-06
UniRef50_Q06187 Cluster: Tyrosine-protein kinase BTK; n=54; Gnat... 54 2e-06
UniRef50_UPI0000E497E3 Cluster: PREDICTED: similar to protein-ty... 54 4e-06
UniRef50_UPI00006A1C31 Cluster: UPI00006A1C31 related cluster; n... 54 4e-06
UniRef50_UPI00006A1C30 Cluster: UPI00006A1C30 related cluster; n... 54 4e-06
UniRef50_Q0PIN0 Cluster: Bam32; n=1; Branchiostoma belcheri tsin... 54 4e-06
UniRef50_Q9H6Q3 Cluster: Src-like-adapter 2; n=21; Euteleostomi|... 54 4e-06
UniRef50_UPI0000D554A0 Cluster: PREDICTED: similar to CG11146-PA... 53 6e-06
UniRef50_Q1ED32 Cluster: Zgc:136231; n=1; Danio rerio|Rep: Zgc:1... 53 6e-06
UniRef50_P05433 Cluster: P47(GAG-CRK) protein; n=3; root|Rep: P4... 53 6e-06
UniRef50_P00521 Cluster: Tyrosine-protein kinase transforming pr... 53 6e-06
UniRef50_Q9BL77 Cluster: C-terminal src kinase protein 1; n=2; C... 53 8e-06
UniRef50_P08631 Cluster: Tyrosine-protein kinase HCK; n=32; Eute... 53 8e-06
UniRef50_UPI00015B496D Cluster: PREDICTED: similar to conserved ... 52 1e-05
UniRef50_UPI0000E49A1C Cluster: PREDICTED: similar to Growth fac... 52 1e-05
UniRef50_UPI0000DB713D Cluster: PREDICTED: similar to CG11146-PA... 52 1e-05
UniRef50_UPI0000D56E93 Cluster: PREDICTED: similar to SH2 domain... 52 1e-05
UniRef50_Q4RNL0 Cluster: Chromosome 21 SCAF15012, whole genome s... 52 1e-05
UniRef50_Q7JVF1 Cluster: LP02169p; n=2; Sophophora|Rep: LP02169p... 52 1e-05
UniRef50_P42680 Cluster: Tyrosine-protein kinase Tec; n=86; Coel... 52 1e-05
UniRef50_UPI000155BA92 Cluster: PREDICTED: similar to Fyn-relate... 52 1e-05
UniRef50_UPI00015A58A4 Cluster: UPI00015A58A4 related cluster; n... 52 1e-05
UniRef50_Q4SR72 Cluster: Chromosome 11 SCAF14528, whole genome s... 52 1e-05
UniRef50_Q9VYM1 Cluster: CG11146-PA; n=2; Coelomata|Rep: CG11146... 52 1e-05
UniRef50_P00528 Cluster: Tyrosine-protein kinase Src64B; n=6; En... 52 1e-05
UniRef50_Q98TP5 Cluster: C-Src protein-tyrosine kinase; n=5; Eut... 51 2e-05
UniRef50_Q5ZM15 Cluster: Putative uncharacterized protein; n=3; ... 51 3e-05
UniRef50_Q4TEC1 Cluster: Chromosome undetermined SCAF5507, whole... 51 3e-05
UniRef50_P51451 Cluster: Tyrosine-protein kinase BLK; n=5; Eutel... 51 3e-05
UniRef50_UPI0000F1D8DB Cluster: PREDICTED: hypothetical protein;... 50 5e-05
UniRef50_UPI0000D55B96 Cluster: PREDICTED: similar to Tyrosine-p... 50 5e-05
UniRef50_UPI000065F097 Cluster: Hematopoietic SH2 domain-contain... 50 5e-05
UniRef50_Q29G65 Cluster: GA20849-PA; n=1; Drosophila pseudoobscu... 50 5e-05
UniRef50_Q15464 Cluster: SH2 domain-containing adapter protein B... 50 5e-05
UniRef50_Q06124 Cluster: Tyrosine-protein phosphatase non-recept... 50 5e-05
UniRef50_P29349 Cluster: Tyrosine-protein phosphatase corkscrew;... 50 5e-05
UniRef50_Q9VPU1 Cluster: CG3727-PB, isoform B; n=9; Endopterygot... 50 7e-05
UniRef50_UPI00015B6424 Cluster: PREDICTED: similar to CG8146-PA;... 49 9e-05
UniRef50_UPI0000DB7BD4 Cluster: PREDICTED: similar to Suppressor... 49 9e-05
UniRef50_Q7YZX2 Cluster: Bruton's tyrosine kinase-like protein; ... 49 9e-05
UniRef50_A0NEZ5 Cluster: ENSANGP00000031260; n=4; Culicidae|Rep:... 49 9e-05
UniRef50_Q60I21 Cluster: TEC family protein tyrosine kinase; n=1... 49 1e-04
UniRef50_Q8T6F8 Cluster: SRC-1; n=3; Caenorhabditis|Rep: SRC-1 -... 49 1e-04
UniRef50_O18683 Cluster: P60 protein; n=2; Sophophora|Rep: P60 p... 49 1e-04
UniRef50_A1L2D2 Cluster: Zgc:158798; n=7; Clupeocephala|Rep: Zgc... 48 2e-04
UniRef50_Q9VX18 Cluster: CG8146-PA; n=1; Drosophila melanogaster... 48 2e-04
UniRef50_O75815 Cluster: Breast cancer anti-estrogen resistance ... 48 2e-04
UniRef50_UPI00006A0536 Cluster: Nck1-prov protein.; n=1; Xenopus... 40 2e-04
UniRef50_UPI0000D559E9 Cluster: PREDICTED: similar to CG8146-PA;... 48 2e-04
UniRef50_UPI00006A214E Cluster: SH2 domain-containing adapter pr... 48 2e-04
UniRef50_Q7T0U4 Cluster: MGC68984 protein; n=2; Xenopus|Rep: MGC... 48 2e-04
UniRef50_Q17MF5 Cluster: Tyrosine-protein kinase; n=2; Culicidae... 48 2e-04
UniRef50_Q5BXT3 Cluster: SJCHGC03955 protein; n=1; Schistosoma j... 48 3e-04
UniRef50_Q16IP4 Cluster: Phosphatidylinositol 3-kinase regulator... 48 3e-04
UniRef50_UPI00015B564A Cluster: PREDICTED: similar to CRK protei... 47 4e-04
UniRef50_UPI0000F2B3BE Cluster: PREDICTED: similar to Src-like-a... 47 4e-04
UniRef50_UPI0000D57699 Cluster: PREDICTED: similar to CG18247-PA... 47 4e-04
UniRef50_UPI00005A0859 Cluster: PREDICTED: similar to SH2 domain... 47 4e-04
UniRef50_Q6DEM2 Cluster: V-crk sarcoma virus CT10 oncogene homol... 47 4e-04
UniRef50_Q6NP28 Cluster: LP09923p; n=6; Endopterygota|Rep: LP099... 47 4e-04
UniRef50_Q5SQS7 Cluster: Novel SH2 domain-containing protein; n=... 47 4e-04
UniRef50_Q5VZ18 Cluster: SH2 domain-containing adapter protein E... 47 4e-04
UniRef50_UPI0000519A8B Cluster: PREDICTED: similar to Phosphatid... 47 5e-04
UniRef50_UPI00015A4B5A Cluster: protein tyrosine phosphatase, no... 47 5e-04
UniRef50_Q85476 Cluster: (recovered insertion mutant of B77) src... 47 5e-04
UniRef50_Q4S6Q5 Cluster: Chromosome undetermined SCAF14724, whol... 47 5e-04
UniRef50_Q13882 Cluster: Tyrosine-protein kinase 6; n=11; Mammal... 47 5e-04
UniRef50_Q9UN19 Cluster: Dual adapter for phosphotyrosine and 3-... 47 5e-04
UniRef50_UPI0000E49CFC Cluster: PREDICTED: similar to Ras GTPase... 46 7e-04
UniRef50_UPI0000D8C686 Cluster: Breast cancer anti-estrogen resi... 46 7e-04
UniRef50_UPI0000ECD739 Cluster: Cytoplasmic tyrosine-protein kin... 46 7e-04
UniRef50_Q3ZB94 Cluster: Zgc:113360; n=3; Clupeocephala|Rep: Zgc... 46 7e-04
UniRef50_Q9NH62 Cluster: Tyrosine kinase 5; n=2; Schistosoma man... 46 7e-04
UniRef50_Q9H3Y6 Cluster: Tyrosine-protein kinase Srms; n=17; Amn... 46 7e-04
UniRef50_Q96JZ2 Cluster: Hematopoietic SH2 domain-containing pro... 46 7e-04
UniRef50_UPI0000F2002E Cluster: PREDICTED: hypothetical protein;... 46 9e-04
UniRef50_UPI0000E479E4 Cluster: PREDICTED: similar to Sh2d3c-pro... 46 9e-04
UniRef50_UPI0000E460CB Cluster: PREDICTED: similar to V-crk sarc... 46 0.001
UniRef50_UPI000051A29D Cluster: PREDICTED: similar to SHC-adapto... 46 0.001
UniRef50_Q56A36 Cluster: Hematopoietic SH2 domain-containing pro... 46 0.001
UniRef50_UPI00015B62FA Cluster: PREDICTED: similar to ras gtpase... 45 0.002
UniRef50_UPI0000E4816C Cluster: PREDICTED: similar to phosphoino... 45 0.002
UniRef50_UPI0000E47C6E Cluster: PREDICTED: similar to Grb2 adapt... 45 0.002
UniRef50_Q1LX18 Cluster: Novel protein similar to vertebrate src... 45 0.002
UniRef50_Q9BI25 Cluster: SHK1 protein; n=2; Dictyostelium discoi... 45 0.002
UniRef50_Q7QG48 Cluster: ENSANGP00000010943; n=1; Anopheles gamb... 45 0.002
UniRef50_Q17PR7 Cluster: Putative uncharacterized protein; n=1; ... 45 0.002
UniRef50_Q16XX9 Cluster: Tyrosine-protein kinase shark; n=2; Cul... 45 0.002
UniRef50_Q08881 Cluster: Tyrosine-protein kinase ITK/TSK; n=18; ... 45 0.002
UniRef50_UPI0000F207BA Cluster: PREDICTED: hypothetical protein;... 44 0.003
UniRef50_UPI0000D57904 Cluster: PREDICTED: similar to CG9098-PA,... 44 0.003
UniRef50_A7SCW1 Cluster: Predicted protein; n=1; Nematostella ve... 44 0.003
UniRef50_Q9NSE2 Cluster: Cytokine-inducible SH2-containing prote... 44 0.003
UniRef50_UPI0000D5590C Cluster: PREDICTED: similar to Suppressor... 44 0.005
UniRef50_UPI0000D555ED Cluster: PREDICTED: similar to CG32406-PA... 44 0.005
UniRef50_Q4RUJ0 Cluster: Chromosome 1 SCAF14995, whole genome sh... 44 0.005
UniRef50_Q08BY6 Cluster: Zgc:153964; n=3; Danio rerio|Rep: Zgc:1... 44 0.005
UniRef50_A7RR81 Cluster: Predicted protein; n=1; Nematostella ve... 44 0.005
UniRef50_UPI0000F1F923 Cluster: PREDICTED: similar to SH2 domain... 43 0.006
UniRef50_UPI0000E48882 Cluster: PREDICTED: similar to tensin hom... 43 0.006
UniRef50_UPI0000567587 Cluster: PREDICTED: hypothetical protein;... 43 0.006
UniRef50_Q9VRS2 Cluster: CG32406-PA; n=3; Sophophora|Rep: CG3240... 43 0.006
UniRef50_Q9N597 Cluster: Phosphoinositide kinase adapter subunit... 43 0.006
UniRef50_O14544 Cluster: Suppressor of cytokine signaling 6; n=2... 43 0.006
UniRef50_Q13239 Cluster: SRC-like-adapter; n=26; Euteleostomi|Re... 43 0.006
UniRef50_Q9NP31 Cluster: SH2 domain-containing protein 2A; n=23;... 43 0.006
UniRef50_P42679 Cluster: Megakaryocyte-associated tyrosine-prote... 43 0.006
UniRef50_Q9NZM3 Cluster: Intersectin-2; n=40; Euteleostomi|Rep: ... 43 0.006
UniRef50_P08630 Cluster: Tyrosine-protein kinase Btk29A; n=10; E... 43 0.006
UniRef50_UPI00015A6A53 Cluster: hypothetical protein LOC406311; ... 43 0.008
UniRef50_Q6PBV3 Cluster: Zgc:73230; n=2; Danio rerio|Rep: Zgc:73... 43 0.008
UniRef50_Q8WP81 Cluster: Putative uncharacterized protein; n=2; ... 43 0.008
UniRef50_Q7Q6Z7 Cluster: ENSANGP00000017664; n=1; Anopheles gamb... 43 0.008
UniRef50_O44235 Cluster: HrSH2 protein; n=1; Halocynthia roretzi... 43 0.008
UniRef50_Q24145 Cluster: Tyrosine-protein kinase shark; n=2; Sop... 43 0.008
UniRef50_Q15811 Cluster: Intersectin-1; n=93; Eumetazoa|Rep: Int... 43 0.008
UniRef50_Q9Y1X9 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 42 0.011
UniRef50_Q9TYT3 Cluster: Putative uncharacterized protein; n=5; ... 42 0.011
UniRef50_Q8INY1 Cluster: CG15154-PB, isoform B; n=6; Coelomata|R... 42 0.011
UniRef50_A7SGW3 Cluster: Predicted protein; n=1; Nematostella ve... 42 0.011
UniRef50_P16591 Cluster: Proto-oncogene tyrosine-protein kinase ... 42 0.011
UniRef50_Q9XYM0 Cluster: Adapter molecule Crk; n=7; Endopterygot... 42 0.011
UniRef50_UPI00015B6133 Cluster: PREDICTED: similar to protein ty... 42 0.014
UniRef50_UPI00015B5EF2 Cluster: PREDICTED: similar to ENSANGP000... 42 0.014
UniRef50_Q4RUN4 Cluster: Chromosome 12 SCAF14993, whole genome s... 42 0.019
UniRef50_Q9VMJ4 Cluster: CG9098-PA, isoform A; n=5; Diptera|Rep:... 42 0.019
UniRef50_Q554D0 Cluster: Signal transducer and activator of tran... 42 0.019
UniRef50_Q380D8 Cluster: ENSANGP00000027059; n=2; Culicidae|Rep:... 42 0.019
UniRef50_Q29LD7 Cluster: GA13535-PA; n=1; Drosophila pseudoobscu... 42 0.019
UniRef50_P98077 Cluster: SHC-transforming protein 2; n=15; Tetra... 42 0.019
UniRef50_P20936 Cluster: Ras GTPase-activating protein 1; n=50; ... 42 0.019
UniRef50_Q6VYH9 Cluster: Hematopoietic SH2 domain-containing pro... 42 0.019
UniRef50_UPI0000DB7263 Cluster: PREDICTED: similar to Suppressor... 41 0.025
UniRef50_Q86SD5 Cluster: Tensin homologue; n=1; Ciona intestinal... 41 0.025
UniRef50_Q8N5H7 Cluster: SH2 domain-containing protein 3C; n=33;... 41 0.025
UniRef50_UPI0000660CF8 Cluster: Crk-like protein.; n=3; Euteleos... 41 0.033
UniRef50_UPI000065F386 Cluster: Homolog of Homo sapiens "Interse... 41 0.033
UniRef50_UPI000065CF8C Cluster: SH2 domain-containing protein 3C... 41 0.033
UniRef50_Q4SKC0 Cluster: Chromosome 13 SCAF14566, whole genome s... 41 0.033
UniRef50_Q4RIA8 Cluster: Chromosome 8 SCAF15044, whole genome sh... 41 0.033
UniRef50_A4II17 Cluster: Putative uncharacterized protein; n=3; ... 41 0.033
UniRef50_O08526 Cluster: Vav-T; n=6; Euteleostomi|Rep: Vav-T - M... 41 0.033
UniRef50_Q95ZL4 Cluster: Temporarily assigned gene name protein ... 41 0.033
UniRef50_Q8IR23 Cluster: CG9209-PA, isoform A; n=6; Endopterygot... 41 0.033
UniRef50_A7SKN8 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 41 0.033
UniRef50_Q91ZA6 Cluster: Suppressor of cytokine signaling 4; n=1... 41 0.033
UniRef50_P29350 Cluster: Tyrosine-protein phosphatase non-recept... 41 0.033
UniRef50_O00160 Cluster: Myosin-If; n=30; Euteleostomi|Rep: Myos... 41 0.033
UniRef50_UPI0000F1F44E Cluster: PREDICTED: similar to Src-like-a... 40 0.043
UniRef50_UPI0000E811F8 Cluster: PREDICTED: similar to SH2D3C pro... 40 0.043
UniRef50_Q8AVM4 Cluster: Sh2d3c-prov protein; n=5; Euteleostomi|... 40 0.043
UniRef50_Q4SBL7 Cluster: Chromosome 15 SCAF14667, whole genome s... 40 0.043
UniRef50_Q4RUJ4 Cluster: Chromosome 1 SCAF14995, whole genome sh... 40 0.043
UniRef50_Q21055 Cluster: Protein tyrosine phosphatase protein 2;... 40 0.043
UniRef50_Q17AB7 Cluster: Putative uncharacterized protein; n=1; ... 40 0.043
UniRef50_Q5T4P1 Cluster: Phosphoinositide-3-kinase, regulatory s... 40 0.043
UniRef50_Q5T286 Cluster: Novel protein; n=8; Theria|Rep: Novel p... 40 0.043
UniRef50_O15357 Cluster: Phosphatidylinositol-3,4,5-trisphosphat... 40 0.043
UniRef50_O00459 Cluster: Phosphatidylinositol 3-kinase regulator... 40 0.043
UniRef50_Q6XZF7 Cluster: Dynamin-binding protein; n=12; Eutheria... 40 0.043
UniRef50_UPI0000D5672D Cluster: PREDICTED: similar to CG3208-PA,... 40 0.057
UniRef50_Q4SM05 Cluster: Chromosome 13 SCAF14555, whole genome s... 40 0.057
UniRef50_Q4H2S5 Cluster: Suppressor of cytokine signaling; n=1; ... 40 0.057
UniRef50_UPI00015B50BA Cluster: PREDICTED: similar to suppressor... 40 0.075
UniRef50_UPI0000F1F0F1 Cluster: PREDICTED: hypothetical protein;... 40 0.075
UniRef50_P52735 Cluster: Protein vav-2; n=28; Euteleostomi|Rep: ... 40 0.075
UniRef50_UPI0000F201D0 Cluster: PREDICTED: hypothetical protein;... 39 0.099
UniRef50_UPI0000F1E232 Cluster: PREDICTED: hypothetical protein;... 39 0.099
UniRef50_UPI0000E45D4F Cluster: PREDICTED: similar to SH2 domain... 39 0.099
UniRef50_Q4T639 Cluster: Chromosome undetermined SCAF8942, whole... 39 0.099
UniRef50_Q4SMI9 Cluster: Chromosome 18 SCAF14547, whole genome s... 39 0.099
UniRef50_Q4S131 Cluster: Chromosome 1 SCAF14770, whole genome sh... 39 0.099
UniRef50_Q4RPN2 Cluster: Chromosome 12 SCAF15007, whole genome s... 39 0.099
UniRef50_A2BDR6 Cluster: SH2 domain containing 3C; n=5; Danio re... 39 0.099
UniRef50_Q9Y1Y2 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 39 0.099
UniRef50_Q54U31 Cluster: SH2 domain-containing protein; n=1; Dic... 39 0.099
UniRef50_A7RRM1 Cluster: Predicted protein; n=1; Nematostella ve... 39 0.099
UniRef50_O75159 Cluster: Suppressor of cytokine signaling 5; n=3... 39 0.099
UniRef50_Q2I6J0 Cluster: Phosphatidylinositol-3,4,5-trisphosphat... 39 0.099
UniRef50_UPI000155BC71 Cluster: PREDICTED: similar to inositol p... 39 0.13
UniRef50_UPI0000F1F169 Cluster: PREDICTED: hypothetical protein;... 39 0.13
UniRef50_UPI0000D56397 Cluster: PREDICTED: similar to Tensin-1; ... 39 0.13
UniRef50_UPI00004992D9 Cluster: hypothetical protein 68.t00030; ... 39 0.13
UniRef50_UPI000065FE19 Cluster: SHC-transforming protein 1 (SH2 ... 39 0.13
UniRef50_Q4S3B2 Cluster: Chromosome 4 SCAF14752, whole genome sh... 39 0.13
UniRef50_Q4RQV0 Cluster: Chromosome 2 SCAF15004, whole genome sh... 39 0.13
UniRef50_Q4RP74 Cluster: Chromosome 1 SCAF15008, whole genome sh... 39 0.13
UniRef50_Q4RIB1 Cluster: Chromosome 8 SCAF15044, whole genome sh... 39 0.13
UniRef50_A7T8K3 Cluster: Predicted protein; n=1; Nematostella ve... 39 0.13
UniRef50_A4F2N7 Cluster: Mt-tensin-b; n=2; Molgula tectiformis|R... 39 0.13
UniRef50_Q5T185 Cluster: SHC (Src homology 2 domain containing) ... 39 0.13
UniRef50_Q59HB0 Cluster: SHC (Src homology 2 domain containing) ... 39 0.13
UniRef50_A4R2P0 Cluster: Putative uncharacterized protein; n=1; ... 39 0.13
UniRef50_Q92529 Cluster: SHC-transforming protein 3; n=34; Eutel... 39 0.13
UniRef50_P29353 Cluster: SHC-transforming protein 1; n=46; Tetra... 39 0.13
UniRef50_P19174 Cluster: 1-phosphatidylinositol-4,5-bisphosphate... 39 0.13
UniRef50_UPI0000D9E331 Cluster: PREDICTED: similar to Suppressor... 38 0.17
UniRef50_Q6NR09 Cluster: RE08107p; n=6; Diptera|Rep: RE08107p - ... 38 0.17
UniRef50_Q54BD4 Cluster: Transcriptional repressor; n=2; Dictyos... 38 0.17
UniRef50_A7RU23 Cluster: Predicted protein; n=1; Nematostella ve... 38 0.17
UniRef50_A0ZX79 Cluster: Osteoclast-stimulating factor; n=1; Sub... 38 0.17
UniRef50_A5DTH4 Cluster: Putative uncharacterized protein; n=1; ... 38 0.17
UniRef50_O14512 Cluster: Suppressor of cytokine signaling 7; n=1... 38 0.17
UniRef50_Q90X67 Cluster: Suppressor of cytokine signaling 3; n=1... 38 0.17
UniRef50_UPI0000E483A8 Cluster: PREDICTED: similar to plenty of ... 38 0.23
UniRef50_UPI0000DB7AEC Cluster: PREDICTED: similar to Suppressor... 38 0.23
UniRef50_UPI00005A2FA4 Cluster: PREDICTED: similar to tensin-lik... 38 0.23
UniRef50_Q4SZG7 Cluster: Chromosome 18 SCAF11624, whole genome s... 38 0.23
UniRef50_Q4SRP3 Cluster: Chromosome undetermined SCAF14505, whol... 38 0.23
UniRef50_Q4RG84 Cluster: Chromosome 2 SCAF15106, whole genome sh... 38 0.23
UniRef50_Q9VIF7 Cluster: CG1099-PA, isoform A; n=8; Sophophora|R... 38 0.23
UniRef50_Q7PWA1 Cluster: ENSANGP00000005190; n=2; Culicidae|Rep:... 38 0.23
UniRef50_Q60UZ3 Cluster: Putative uncharacterized protein CBG197... 38 0.23
UniRef50_Q5BW49 Cluster: SJCHGC04880 protein; n=1; Schistosoma j... 38 0.23
UniRef50_O14796 Cluster: SH2 domain-containing protein 1B; n=19;... 38 0.23
UniRef50_O43125 Cluster: Protein csh3; n=1; Schizosaccharomyces ... 38 0.23
UniRef50_UPI0000E47660 Cluster: PREDICTED: similar to NPHP1 prot... 38 0.30
UniRef50_UPI0000DB7594 Cluster: PREDICTED: similar to CG9098-PA,... 38 0.30
UniRef50_UPI0000ECA015 Cluster: Suppressor of cytokine signaling... 38 0.30
UniRef50_Q5BXE5 Cluster: SJCHGC04002 protein; n=1; Schistosoma j... 38 0.30
UniRef50_O45498 Cluster: Putative uncharacterized protein; n=1; ... 38 0.30
UniRef50_Q875L6 Cluster: Guanyl nucleotide exchange factor Sql2;... 38 0.30
UniRef50_Q59PV2 Cluster: Putative uncharacterized protein; n=3; ... 38 0.30
UniRef50_Q0UIK1 Cluster: Putative uncharacterized protein; n=1; ... 38 0.30
UniRef50_O14543 Cluster: Suppressor of cytokine signaling 3; n=2... 38 0.30
UniRef50_O14508 Cluster: Suppressor of cytokine signaling 2; n=2... 38 0.30
UniRef50_Q9D7V1 Cluster: SH2 domain-containing protein 4A; n=4; ... 38 0.30
UniRef50_UPI0000F1D282 Cluster: PREDICTED: hypothetical protein;... 37 0.40
UniRef50_UPI0000E818A6 Cluster: PREDICTED: similar to Myosin-VII... 37 0.40
UniRef50_UPI0000E8080B Cluster: PREDICTED: similar to TUBA; n=3;... 37 0.40
UniRef50_UPI000069FBD8 Cluster: tensin like C1 domain containing... 37 0.40
UniRef50_UPI000069FBD7 Cluster: tensin like C1 domain containing... 37 0.40
UniRef50_UPI000069FBD6 Cluster: tensin like C1 domain containing... 37 0.40
UniRef50_UPI0000ECB580 Cluster: UPI0000ECB580 related cluster; n... 37 0.40
UniRef50_Q4SII9 Cluster: Chromosome 5 SCAF14581, whole genome sh... 37 0.40
UniRef50_Q4RXL6 Cluster: Chromosome 11 SCAF14979, whole genome s... 37 0.40
UniRef50_Q9W4A9 Cluster: CG3208-PA, isoform A; n=5; Diptera|Rep:... 37 0.40
UniRef50_P32793 Cluster: Protein YSC84; n=8; Saccharomycetales|R... 37 0.40
UniRef50_UPI0000F2E785 Cluster: PREDICTED: hypothetical protein;... 37 0.53
UniRef50_UPI0000D5669C Cluster: PREDICTED: similar to CG31302-PA... 37 0.53
UniRef50_Q7QHE3 Cluster: ENSANGP00000022029; n=2; Anopheles gamb... 37 0.53
UniRef50_A7SPF7 Cluster: Predicted protein; n=1; Nematostella ve... 37 0.53
UniRef50_A7RGQ1 Cluster: Predicted protein; n=1; Nematostella ve... 37 0.53
UniRef50_A7RFH8 Cluster: Predicted protein; n=1; Nematostella ve... 37 0.53
UniRef50_A4VB01 Cluster: Putative uncharacterized protein; n=1; ... 37 0.53
UniRef50_A1C8D2 Cluster: Actin binding protein, putative; n=4; E... 37 0.53
UniRef50_Q09746 Cluster: Uncharacterized protein C12C2.05c; n=1;... 37 0.53
UniRef50_Q63HR2 Cluster: Tensin-like C1 domain-containing phosph... 37 0.53
UniRef50_Q8T390 Cluster: SH3-containing GRB2-like protein; n=7; ... 37 0.53
UniRef50_P19706 Cluster: Myosin heavy chain IB; n=5; Eukaryota|R... 37 0.53
UniRef50_UPI0000F1E3ED Cluster: PREDICTED: similar to cardiac mu... 36 0.70
UniRef50_UPI0000D577DA Cluster: PREDICTED: similar to CG7893-PA,... 36 0.70
UniRef50_Q6P8E0 Cluster: Suppressor of cytokine signaling 3; n=2... 36 0.70
UniRef50_Q4TD11 Cluster: Chromosome undetermined SCAF6586, whole... 36 0.70
UniRef50_Q4SM94 Cluster: Chromosome 3 SCAF14553, whole genome sh... 36 0.70
UniRef50_Q08BW5 Cluster: Zgc:154062; n=1; Danio rerio|Rep: Zgc:1... 36 0.70
UniRef50_Q54Y55 Cluster: SH2 domain-containing protein; n=1; Dic... 36 0.70
UniRef50_Q54G43 Cluster: SH2 domain-containing protein; n=1; Dic... 36 0.70
UniRef50_Q4H2S4 Cluster: Suppressor of cytokine signaling; n=1; ... 36 0.70
UniRef50_Q22070 Cluster: Putative uncharacterized protein plc-3;... 36 0.70
UniRef50_O00851 Cluster: Unconventional myosin IB; n=2; Entamoeb... 36 0.70
UniRef50_A7T185 Cluster: Predicted protein; n=1; Nematostella ve... 36 0.70
UniRef50_A7SJB4 Cluster: Predicted protein; n=1; Nematostella ve... 36 0.70
UniRef50_A7EMU6 Cluster: Putative uncharacterized protein; n=2; ... 36 0.70
UniRef50_O13736 Cluster: SH3 domain-containing protein C16E8.01;... 36 0.70
UniRef50_Q68CZ2 Cluster: Tensin-3; n=33; Euteleostomi|Rep: Tensi... 36 0.70
UniRef50_O88890 Cluster: SH2 domain-containing protein 1A; n=8; ... 36 0.70
UniRef50_O60880 Cluster: SH2 domain-containing protein 1A; n=18;... 36 0.70
UniRef50_UPI00015B58E2 Cluster: PREDICTED: similar to signal tra... 36 0.93
UniRef50_UPI0000E48523 Cluster: PREDICTED: similar to protein-ty... 36 0.93
UniRef50_UPI0000E1FA37 Cluster: PREDICTED: similar to signaling ... 36 0.93
UniRef50_UPI0000D562ED Cluster: PREDICTED: similar to growth fac... 36 0.93
UniRef50_UPI0000D55E0B Cluster: PREDICTED: similar to CG4909-PA;... 36 0.93
UniRef50_UPI000058773D Cluster: PREDICTED: hypothetical protein;... 36 0.93
UniRef50_UPI000058720B Cluster: PREDICTED: hypothetical protein;... 36 0.93
UniRef50_UPI00006A0ADF Cluster: Tensin-1.; n=5; Xenopus tropical... 36 0.93
UniRef50_UPI0000503A18 Cluster: UPI0000503A18 related cluster; n... 36 0.93
UniRef50_Q4SIP6 Cluster: Chromosome 21 SCAF14577, whole genome s... 36 0.93
UniRef50_Q1KL02 Cluster: Chimerin 2; n=3; Tetraodontidae|Rep: Ch... 36 0.93
UniRef50_A1YTM4 Cluster: Intersectin; n=1; Lampetra fluviatilis|... 36 0.93
UniRef50_Q9GYK6 Cluster: Putative uncharacterized protein; n=4; ... 36 0.93
UniRef50_Q5DEG7 Cluster: SJCHGC01831 protein; n=1; Schistosoma j... 36 0.93
UniRef50_Q54XJ7 Cluster: Putative uncharacterized protein; n=1; ... 36 0.93
UniRef50_Q4R1Q6 Cluster: Neutrophil cytosolic factor 1; n=1; Cio... 36 0.93
UniRef50_Q16GQ1 Cluster: Putative uncharacterized protein; n=1; ... 36 0.93
UniRef50_Q4WXP7 Cluster: Cell division control protein (Cdc15), ... 36 0.93
UniRef50_A2R7N0 Cluster: Contig An16c0150, complete genome; n=2;... 36 0.93
UniRef50_Q9UKW4 Cluster: Protein vav-3; n=96; Euteleostomi|Rep: ... 36 0.93
UniRef50_Q92835 Cluster: Phosphatidylinositol-3,4,5-trisphosphat... 36 0.93
UniRef50_UPI0000E48B80 Cluster: PREDICTED: hypothetical protein;... 36 1.2
UniRef50_UPI0000D55A08 Cluster: PREDICTED: similar to intersecti... 36 1.2
UniRef50_UPI0000498477 Cluster: hypothetical protein 26.t00042; ... 36 1.2
UniRef50_UPI00015A734B Cluster: SH3 multiple domains 2 like; n=1... 36 1.2
UniRef50_UPI000069FF5A Cluster: Dynamin-binding protein (Scaffol... 36 1.2
UniRef50_UPI0000ECCD76 Cluster: tensin 3; n=1; Gallus gallus|Rep... 36 1.2
UniRef50_Q7SZY5 Cluster: Novel protein similar to chicken and hu... 36 1.2
UniRef50_Q6NRD3 Cluster: Posh protein; n=4; Tetrapoda|Rep: Posh ... 36 1.2
UniRef50_A5D8S5 Cluster: Si:dkey-15j16.4 protein; n=10; Euteleos... 36 1.2
UniRef50_A2AHL9 Cluster: Novel protein containing SH3 domains; n... 36 1.2
UniRef50_Q9VXQ2 Cluster: CG8948-PA, isoform A; n=5; Diptera|Rep:... 36 1.2
UniRef50_Q9U2Z5 Cluster: Putative uncharacterized protein; n=2; ... 36 1.2
UniRef50_Q8T7Z1 Cluster: Mlk (Mixed lineage kinase) homolog prot... 36 1.2
UniRef50_Q8T7Z0 Cluster: Mlk (Mixed lineage kinase) homolog prot... 36 1.2
UniRef50_Q7QK19 Cluster: ENSANGP00000019768; n=1; Anopheles gamb... 36 1.2
UniRef50_Q19726 Cluster: Putative uncharacterized protein kin-14... 36 1.2
UniRef50_Q10929 Cluster: Putative uncharacterized protein; n=2; ... 36 1.2
UniRef50_O97034 Cluster: PLC-gammaS; n=1; Ephydatia fluviatilis|... 36 1.2
UniRef50_O00910 Cluster: STATa protein; n=2; Dictyostelium disco... 36 1.2
UniRef50_A2IB48 Cluster: Phospholipase C gamma; n=5; Eumetazoa|R... 36 1.2
UniRef50_Q7Z6J0 Cluster: SH3 domain-containing RING finger prote... 36 1.2
UniRef50_Q59GY7 Cluster: Signal transducer and activator of tran... 36 1.2
UniRef50_Q45FX5 Cluster: Protein vav-1; n=4; Caenorhabditis|Rep:... 36 1.2
UniRef50_Q9HBL0 Cluster: Tensin-1; n=44; Eumetazoa|Rep: Tensin-1... 36 1.2
UniRef50_P42229 Cluster: Signal transducer and activator of tran... 36 1.2
UniRef50_P42687 Cluster: Tyrosine-protein kinase SPK-1; n=1; Gir... 36 1.2
UniRef50_P53356 Cluster: Tyrosine-protein kinase HTK16; n=1; Hyd... 36 1.2
UniRef50_UPI0000D57976 Cluster: PREDICTED: similar to CG8948-PA,... 35 1.6
UniRef50_UPI0000D556E6 Cluster: PREDICTED: similar to CD2-associ... 35 1.6
UniRef50_Q4SVT4 Cluster: Chromosome undetermined SCAF13726, whol... 35 1.6
UniRef50_Q4RVK7 Cluster: Chromosome 15 SCAF14992, whole genome s... 35 1.6
UniRef50_Q7Q2Q9 Cluster: ENSANGP00000003425; n=1; Anopheles gamb... 35 1.6
UniRef50_Q17DJ2 Cluster: Signal transduction protein lnk-realted... 35 1.6
UniRef50_A7RUA3 Cluster: Predicted protein; n=1; Nematostella ve... 35 1.6
UniRef50_Q4P3H6 Cluster: Putative uncharacterized protein; n=2; ... 35 1.6
UniRef50_Q8IZW8 Cluster: Tensin-4 precursor; n=17; Eutheria|Rep:... 35 1.6
UniRef50_Q9H788 Cluster: SH2 domain-containing protein 4A (Prote... 35 1.6
UniRef50_UPI0000E7F989 Cluster: PREDICTED: similar to 1-phosphat... 35 2.1
UniRef50_Q9Y0S9 Cluster: CG9749-PA; n=7; Endopterygota|Rep: CG97... 35 2.1
UniRef50_Q7K137 Cluster: LD10453p; n=4; Diptera|Rep: LD10453p - ... 35 2.1
UniRef50_Q5C0L2 Cluster: SJCHGC05893 protein; n=1; Schistosoma j... 35 2.1
UniRef50_Q16H73 Cluster: Putative uncharacterized protein; n=1; ... 35 2.1
UniRef50_A0NFK4 Cluster: ENSANGP00000030373; n=2; Coelomata|Rep:... 35 2.1
UniRef50_Q6CXH0 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 35 2.1
UniRef50_Q5AS57 Cluster: Putative uncharacterized protein; n=1; ... 35 2.1
UniRef50_Q4PGV7 Cluster: Putative uncharacterized protein; n=1; ... 35 2.1
UniRef50_Q04205 Cluster: Tensin; n=12; Euteleostomi|Rep: Tensin ... 35 2.1
UniRef50_Q8TEJ3 Cluster: SH3 multiple domains protein 4 precurso... 35 2.1
UniRef50_P15891 Cluster: Actin-binding protein; n=4; Saccharomyc... 35 2.1
UniRef50_UPI0000F2115F Cluster: PREDICTED: similar to tensin lik... 34 2.8
UniRef50_UPI0000E47DD5 Cluster: PREDICTED: similar to endophilin... 34 2.8
UniRef50_Q4S782 Cluster: Chromosome undetermined SCAF14718, whol... 34 2.8
UniRef50_Q4RX78 Cluster: Chromosome 11 SCAF14979, whole genome s... 34 2.8
UniRef50_Q54JS2 Cluster: Putative uncharacterized protein; n=1; ... 34 2.8
UniRef50_Q17MI2 Cluster: Dab2-interacting protein; n=2; Culicida... 34 2.8
UniRef50_O77440 Cluster: Protein-tyrosine kinase HTK98; n=1; Hyd... 34 2.8
UniRef50_Q5VSN0 Cluster: SH3-domain kinase binding protein 1; n=... 34 2.8
UniRef50_Q2GSS9 Cluster: Putative uncharacterized protein; n=1; ... 34 2.8
UniRef50_A5DFV9 Cluster: Putative uncharacterized protein; n=1; ... 34 2.8
UniRef50_A4R8V8 Cluster: Putative uncharacterized protein; n=2; ... 34 2.8
UniRef50_Q96B97 Cluster: SH3 domain-containing kinase-binding pr... 34 2.8
UniRef50_UPI00015B465F Cluster: PREDICTED: similar to rab gdp/gt... 34 3.7
UniRef50_UPI0001554DF6 Cluster: PREDICTED: similar to KIAA0612 p... 34 3.7
UniRef50_UPI0000589301 Cluster: PREDICTED: similar to SH3 and PX... 34 3.7
UniRef50_UPI000049A4E0 Cluster: SH3 domain protein; n=2; Entamoe... 34 3.7
UniRef50_UPI0000660CE1 Cluster: Homolog of Brachydanio rerio "Ph... 34 3.7
UniRef50_UPI0000ECCA55 Cluster: CD2-associated protein (Cas liga... 34 3.7
UniRef50_O60880-5 Cluster: Isoform E of O60880 ; n=5; Eutheria|R... 34 3.7
UniRef50_Q13322-2 Cluster: Isoform 1 of Q13322 ; n=5; Homo/Pan/G... 34 3.7
UniRef50_Q5RJ36 Cluster: Novel protein similar to vertebrate lym... 34 3.7
UniRef50_Q4SS18 Cluster: Chromosome undetermined SCAF14482, whol... 34 3.7
UniRef50_Q5XJV9 Cluster: Bzrap1 protein; n=4; Murinae|Rep: Bzrap... 34 3.7
UniRef50_Q7MU74 Cluster: Glycogen debranching enzyme, archaeal t... 34 3.7
UniRef50_Q9VDI1 Cluster: CG33094-PB; n=6; Endopterygota|Rep: CG3... 34 3.7
UniRef50_Q8MML2 Cluster: SYNAPTIC DYNAMIN-ASSOCIATED PROTEIN IIB... 34 3.7
UniRef50_Q7PJI7 Cluster: ENSANGP00000022823; n=3; Endopterygota|... 34 3.7
UniRef50_A7SPX6 Cluster: Predicted protein; n=1; Nematostella ve... 34 3.7
UniRef50_Q92882 Cluster: Osteoclast-stimulating factor 1; n=33; ... 34 3.7
UniRef50_Q13322 Cluster: Growth factor receptor-bound protein 10... 34 3.7
UniRef50_Q9Y5K6 Cluster: CD2-associated protein; n=26; Tetrapoda... 34 3.7
UniRef50_Q9P7E8 Cluster: Protein app1; n=2; Fungi/Metazoa group|... 34 3.7
UniRef50_UPI0000E47B1C Cluster: PREDICTED: similar to TUBA; n=2;... 33 4.9
UniRef50_UPI0000E24EBC Cluster: PREDICTED: SH3-domain GRB2-like ... 33 4.9
UniRef50_UPI0000DB7965 Cluster: PREDICTED: similar to CAP CG1840... 33 4.9
UniRef50_UPI0000D57912 Cluster: PREDICTED: similar to CG4200-PA;... 33 4.9
UniRef50_UPI000069EEDB Cluster: UPI000069EEDB related cluster; n... 33 4.9
UniRef50_Q6RCJ1 Cluster: Cas/HEF-like protein 1; n=2; Xenopus|Re... 33 4.9
UniRef50_Q4T8S5 Cluster: Chromosome 18 SCAF7732, whole genome sh... 33 4.9
UniRef50_Q4RK33 Cluster: Chromosome 2 SCAF15032, whole genome sh... 33 4.9
UniRef50_A0NL77 Cluster: N-acetylmuramoyl-L-alanine amidase; n=2... 33 4.9
UniRef50_Q9N415 Cluster: Temporarily assigned gene name protein ... 33 4.9
UniRef50_A7RK55 Cluster: Predicted protein; n=1; Nematostella ve... 33 4.9
UniRef50_Q6FUB3 Cluster: Similar to sp|Q06449 Saccharomyces cere... 33 4.9
UniRef50_P40763 Cluster: Signal transducer and activator of tran... 33 4.9
UniRef50_P40073 Cluster: Protein SSU81; n=6; Saccharomycetales|R... 33 4.9
UniRef50_O95153 Cluster: Peripheral-type benzodiazepine receptor... 33 4.9
UniRef50_Q12965 Cluster: Myosin-Ie; n=48; Bilateria|Rep: Myosin-... 33 4.9
UniRef50_UPI00015B5D64 Cluster: PREDICTED: similar to LD41184p; ... 33 6.5
UniRef50_UPI0000F1ED8A Cluster: PREDICTED: similar to TNS1 prote... 33 6.5
UniRef50_UPI0000447A3F Cluster: PREDICTED: similar to 1-phosphat... 33 6.5
UniRef50_UPI0000447279 Cluster: PREDICTED: similar to suppressor... 33 6.5
UniRef50_Q4T6N5 Cluster: Chromosome 9 SCAF8684, whole genome sho... 33 6.5
UniRef50_Q9SNF0 Cluster: Myosin; n=14; Magnoliophyta|Rep: Myosin... 33 6.5
UniRef50_Q9VHC3 Cluster: CG9379-PA; n=2; Drosophila melanogaster... 33 6.5
UniRef50_Q7Q350 Cluster: ENSANGP00000004820; n=2; Culicidae|Rep:... 33 6.5
UniRef50_Q6A573 Cluster: Putative uncharacterized protein; n=2; ... 33 6.5
UniRef50_Q5C288 Cluster: SJCHGC09127 protein; n=1; Schistosoma j... 33 6.5
UniRef50_O00886 Cluster: RacGAP protein; n=2; Dictyostelium disc... 33 6.5
UniRef50_A7SC74 Cluster: Predicted protein; n=1; Nematostella ve... 33 6.5
UniRef50_A7RZ47 Cluster: Predicted protein; n=1; Nematostella ve... 33 6.5
UniRef50_A7RMW0 Cluster: Predicted protein; n=1; Nematostella ve... 33 6.5
UniRef50_Q757L7 Cluster: AEL017Wp; n=19; Ascomycota|Rep: AEL017W... 33 6.5
UniRef50_Q4W9Q3 Cluster: Protein kinase activator Bem1, putative... 33 6.5
UniRef50_A5DIJ7 Cluster: Putative uncharacterized protein; n=1; ... 33 6.5
UniRef50_UPI0000F21D00 Cluster: PREDICTED: similar to Vav1 prote... 33 8.6
UniRef50_UPI0000E46C42 Cluster: PREDICTED: similar to Grb14; n=2... 33 8.6
UniRef50_UPI0000D5645D Cluster: PREDICTED: similar to CG17367-PB... 33 8.6
UniRef50_UPI00015A4114 Cluster: Uncharacterized protein KIAA1666... 33 8.6
UniRef50_UPI000065F033 Cluster: Rho guanine nucleotide exchange ... 33 8.6
UniRef50_Q08CL9 Cluster: Zgc:152930; n=13; Euteleostomi|Rep: Zgc... 33 8.6
UniRef50_Q8ZMC2 Cluster: Putative integral membrane protein; n=4... 33 8.6
UniRef50_Q5YQA2 Cluster: Putative uncharacterized protein; n=1; ... 33 8.6
UniRef50_Q5TX51 Cluster: ENSANGP00000026142; n=1; Anopheles gamb... 33 8.6
UniRef50_Q55CT2 Cluster: Putative uncharacterized protein; n=1; ... 33 8.6
UniRef50_Q54FG5 Cluster: Putative uncharacterized protein; n=1; ... 33 8.6
UniRef50_Q16U30 Cluster: Putative uncharacterized protein; n=1; ... 33 8.6
UniRef50_A7T1F0 Cluster: Predicted protein; n=1; Nematostella ve... 33 8.6
UniRef50_A7RVL2 Cluster: Predicted protein; n=1; Nematostella ve... 33 8.6
UniRef50_A5A8Q9 Cluster: Uncoordinated protein 57, isoform c; n=... 33 8.6
UniRef50_P38479 Cluster: Actin-binding protein; n=1; Kazachstani... 33 8.6
>UniRef50_Q7PV64 Cluster: ENSANGP00000020137; n=5; Coelomata|Rep:
ENSANGP00000020137 - Anopheles gambiae str. PEST
Length = 185
Score = 165 bits (402), Expect = 7e-40
Identities = 75/82 (91%), Positives = 77/82 (93%)
Frame = +2
Query: 269 ILNMEDDMNWYRAELDGKEGLIPSNYIQMKNHSWYYGRITRADAEKLLANKPEGGFLIRI 448
ILNMEDDMNWYRAELDGKEGLIPSNYI+MKNH WYYGRITRADAEKLL+NK EG FLIRI
Sbjct: 1 ILNMEDDMNWYRAELDGKEGLIPSNYIEMKNHDWYYGRITRADAEKLLSNKHEGAFLIRI 60
Query: 449 SESSPGDFSLSVKCPDGVQHSK 514
SESSPGDFSLSVKC DGVQH K
Sbjct: 61 SESSPGDFSLSVKCSDGVQHFK 82
Score = 90.6 bits (215), Expect = 3e-17
Identities = 42/47 (89%), Positives = 44/47 (93%)
Frame = +1
Query: 511 KVLRDASSKFFLWVVKFNSLNELVDYHRTASVSRLQDVKLRDVVPEK 651
KVLRDA KFFLWVVKFNSLNELVDYHRTASVSR QDVKLRD+VPE+
Sbjct: 82 KVLRDAQGKFFLWVVKFNSLNELVDYHRTASVSRSQDVKLRDMVPEE 128
>UniRef50_A2AAH7 Cluster: Growth factor receptor bound protein 2;
n=3; Mammalia|Rep: Growth factor receptor bound protein
2 - Mus musculus (Mouse)
Length = 203
Score = 117 bits (281), Expect = 3e-25
Identities = 53/91 (58%), Positives = 70/91 (76%), Gaps = 1/91 (1%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYIQMKNHSWYYGRITRADAEKLLA-NK 421
F + +LK+LN E D NWY+AEL+GK+G IP NYI+MK H W++G+I RA AE++L+ +
Sbjct: 19 FKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQR 78
Query: 422 PEGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
+G FLIR SES+PGDFSLSVK + VQH K
Sbjct: 79 HDGAFLIRESESAPGDFSLSVKFGNDVQHFK 109
Score = 72.5 bits (170), Expect = 9e-12
Identities = 32/43 (74%), Positives = 37/43 (86%)
Frame = +1
Query: 511 KVLRDASSKFFLWVVKFNSLNELVDYHRTASVSRLQDVKLRDV 639
KVLRD + K+FLWVVKFNSLNELVDYHR+ SVSR Q + LRD+
Sbjct: 109 KVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDI 151
Score = 38.7 bits (86), Expect = 0.13
Identities = 16/21 (76%), Positives = 20/21 (95%)
Frame = +3
Query: 192 MEALAKHDFTATADDELSFRK 254
MEA+AK+DF ATADDELSF++
Sbjct: 1 MEAIAKYDFKATADDELSFKR 21
>UniRef50_P62993 Cluster: Growth factor receptor-bound protein 2;
n=26; Euteleostomi|Rep: Growth factor receptor-bound
protein 2 - Homo sapiens (Human)
Length = 217
Score = 117 bits (281), Expect = 3e-25
Identities = 53/91 (58%), Positives = 70/91 (76%), Gaps = 1/91 (1%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYIQMKNHSWYYGRITRADAEKLLA-NK 421
F + +LK+LN E D NWY+AEL+GK+G IP NYI+MK H W++G+I RA AE++L+ +
Sbjct: 19 FKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQR 78
Query: 422 PEGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
+G FLIR SES+PGDFSLSVK + VQH K
Sbjct: 79 HDGAFLIRESESAPGDFSLSVKFGNDVQHFK 109
Score = 72.9 bits (171), Expect = 7e-12
Identities = 34/49 (69%), Positives = 41/49 (83%), Gaps = 2/49 (4%)
Frame = +1
Query: 511 KVLRDASSKFFLWVVKFNSLNELVDYHRTASVSRLQDVKLRDV--VPEK 651
KVLRD + K+FLWVVKFNSLNELVDYHR+ SVSR Q + LRD+ VP++
Sbjct: 109 KVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQ 157
Score = 38.7 bits (86), Expect = 0.13
Identities = 16/21 (76%), Positives = 20/21 (95%)
Frame = +3
Query: 192 MEALAKHDFTATADDELSFRK 254
MEA+AK+DF ATADDELSF++
Sbjct: 1 MEAIAKYDFKATADDELSFKR 21
>UniRef50_Q13588 Cluster: GRB2-related adapter protein; n=21;
Bilateria|Rep: GRB2-related adapter protein - Homo
sapiens (Human)
Length = 217
Score = 113 bits (273), Expect = 3e-24
Identities = 56/91 (61%), Positives = 65/91 (71%), Gaps = 1/91 (1%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYIQMKNHSWYYGRITRADAEKLLANKP 424
F K LKILNMEDD NWY+AEL G EG IP NYI++K H WY GRI+R AE++L +
Sbjct: 19 FNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIRVKPHPWYSGRISRQLAEEILMKRN 78
Query: 425 E-GGFLIRISESSPGDFSLSVKCPDGVQHSK 514
G FLIR SESSPG+FS+SV D VQH K
Sbjct: 79 HLGAFLIRESESSPGEFSVSVNYGDQVQHFK 109
Score = 61.3 bits (142), Expect = 2e-08
Identities = 26/45 (57%), Positives = 36/45 (80%)
Frame = +1
Query: 511 KVLRDASSKFFLWVVKFNSLNELVDYHRTASVSRLQDVKLRDVVP 645
KVLR+AS K+FLW KFNSLNELVD++RT ++++ + + LRD P
Sbjct: 109 KVLREASGKYFLWEEKFNSLNELVDFYRTTTIAKKRQIFLRDEEP 153
>UniRef50_UPI00015A7910 Cluster: hypothetical protein LOC553596;
n=2; Danio rerio|Rep: hypothetical protein LOC553596 -
Danio rerio
Length = 283
Score = 103 bits (248), Expect = 3e-21
Identities = 48/90 (53%), Positives = 61/90 (67%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYIQMKNHSWYYGRITRADAEKLLANKP 424
F K VLKI NMEDD NWY AE ++G +P NYI ++ H+W+ GRI+R AE L +
Sbjct: 19 FQKGDVLKITNMEDDPNWYTAEFVNRKGYVPKNYISLRPHAWFAGRISRHVAENRLHQRD 78
Query: 425 EGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
G FL+R SES+PG+FS+SV D VQH K
Sbjct: 79 CGSFLVRESESAPGEFSMSVSYGDHVQHFK 108
Score = 46.0 bits (104), Expect = 9e-04
Identities = 20/43 (46%), Positives = 31/43 (72%)
Frame = +1
Query: 511 KVLRDASSKFFLWVVKFNSLNELVDYHRTASVSRLQDVKLRDV 639
KVL+D +F+W F SLN+LVDY++T S+++ + V LRD+
Sbjct: 108 KVLKDREGYYFVWEEIFPSLNQLVDYYKTNSIAKERTVFLRDL 150
>UniRef50_Q4V9Q1 Cluster: Zgc:109892; n=11; Euteleostomi|Rep:
Zgc:109892 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 214
Score = 101 bits (243), Expect = 1e-20
Identities = 47/90 (52%), Positives = 61/90 (67%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYIQMKNHSWYYGRITRADAEKLLANKP 424
F K ++LK+ NM+DD NWY AEL G+ G +P NYI ++ H+W+ G I+R AE L
Sbjct: 19 FQKGEILKVTNMDDDPNWYTAELLGRRGYVPKNYINVRPHTWFVGGISRQAAENRLRPLE 78
Query: 425 EGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
G FLIR SES+PG+FS+SV D VQH K
Sbjct: 79 CGAFLIRESESTPGEFSVSVSYGDHVQHFK 108
Score = 45.2 bits (102), Expect = 0.002
Identities = 19/42 (45%), Positives = 31/42 (73%)
Frame = +1
Query: 511 KVLRDASSKFFLWVVKFNSLNELVDYHRTASVSRLQDVKLRD 636
KVL+D ++F+W F+SLN+LVD++R S+++ + V LRD
Sbjct: 108 KVLKDGLGQYFIWDEVFSSLNQLVDFYRINSIAKERTVFLRD 149
>UniRef50_Q4T2Z8 Cluster: Chromosome 18 SCAF10147, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 18 SCAF10147, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 279
Score = 90.2 bits (214), Expect = 4e-17
Identities = 39/80 (48%), Positives = 55/80 (68%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYIQMKNHSWYYGRITRADAEKLLANKP 424
F + V+K+ MEDD W+ AE+ GK G IP NYI + + W+ GR++R +AEK L +
Sbjct: 19 FQEGDVIKVTEMEDDSGWFTAEIQGKRGYIPQNYISLLPYPWFVGRVSRLEAEKRLRWQD 78
Query: 425 EGGFLIRISESSPGDFSLSV 484
G FL+R SES+PG+FS+SV
Sbjct: 79 PGVFLVRESESAPGEFSVSV 98
Score = 34.3 bits (75), Expect = 2.8
Identities = 19/53 (35%), Positives = 29/53 (54%)
Frame = +1
Query: 478 ISQMSGRCPALKVLRDASSKFFLWVVKFNSLNELVDYHRTASVSRLQDVKLRD 636
I R +VL + ++ +W F SLN LVD++RT S++ + V LRD
Sbjct: 129 IVSYGNRVEHFRVL-EGGGQYCIWEESFCSLNRLVDFYRTHSIAMDKVVCLRD 180
>UniRef50_Q4SAX0 Cluster: Chromosome 3 SCAF14679, whole genome
shotgun sequence; n=4; Tetraodontidae|Rep: Chromosome 3
SCAF14679, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 283
Score = 90.2 bits (214), Expect = 4e-17
Identities = 42/90 (46%), Positives = 63/90 (70%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYIQMKNHSWYYGRITRADAEKLLANKP 424
F K +LKIL+ EDD W++AE++G+EG +P NYI+++ W+ +R+ AE+LL +K
Sbjct: 19 FRKGDILKILSPEDD--WFKAEMNGQEGYVPQNYIEIQTPRWFQENASRSAAEELLRHKG 76
Query: 425 EGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
G F+IR +SSPG+FS+SV+ VQH K
Sbjct: 77 VGEFVIRGCQSSPGEFSISVRHESDVQHFK 106
Score = 54.8 bits (126), Expect = 2e-06
Identities = 22/45 (48%), Positives = 35/45 (77%)
Frame = +1
Query: 511 KVLRDASSKFFLWVVKFNSLNELVDYHRTASVSRLQDVKLRDVVP 645
KV+RD+ ++FLW KF SLN+LVD++RT+S+S+ +++ L D P
Sbjct: 106 KVMRDSRGQYFLWSEKFTSLNKLVDFYRTSSISKTREIYLNDGGP 150
Score = 33.5 bits (73), Expect = 4.9
Identities = 15/21 (71%), Positives = 16/21 (76%)
Frame = +3
Query: 192 MEALAKHDFTATADDELSFRK 254
MEA K+DF AT D ELSFRK
Sbjct: 1 MEAQGKYDFMATGDTELSFRK 21
>UniRef50_Q6PE32 Cluster: Zgc:65942; n=2; Danio rerio|Rep: Zgc:65942
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 249
Score = 87.4 bits (207), Expect = 3e-16
Identities = 44/90 (48%), Positives = 57/90 (63%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYIQMKNHSWYYGRITRADAEKLLANKP 424
F K V+KIL DD W+RAE++G EG +P NYI SWY +R A+ L +P
Sbjct: 19 FRKGDVIKILGTNDD--WFRAEINGMEGFVPRNYIVTTFPSWYKENTSRQSAQDELMCQP 76
Query: 425 EGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
G F+IR S+SSPGDFS+SV+ + VQH K
Sbjct: 77 IGAFIIRGSQSSPGDFSISVRHENDVQHFK 106
Score = 41.1 bits (92), Expect = 0.025
Identities = 18/40 (45%), Positives = 26/40 (65%)
Frame = +1
Query: 511 KVLRDASSKFFLWVVKFNSLNELVDYHRTASVSRLQDVKL 630
KV+RD +++LW F SLN+LVDY+ S+S+ V L
Sbjct: 106 KVMRDRQGRYYLWSEMFTSLNKLVDYYTHNSISKQSRVFL 145
Score = 36.3 bits (80), Expect = 0.70
Identities = 16/21 (76%), Positives = 18/21 (85%)
Frame = +3
Query: 192 MEALAKHDFTATADDELSFRK 254
MEA K+DF+ATA DELSFRK
Sbjct: 1 MEATGKYDFSATAGDELSFRK 21
>UniRef50_UPI00015A79D6 Cluster: hypothetical protein LOC550452;
n=1; Danio rerio|Rep: hypothetical protein LOC550452 -
Danio rerio
Length = 250
Score = 87.0 bits (206), Expect = 4e-16
Identities = 43/90 (47%), Positives = 57/90 (63%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYIQMKNHSWYYGRITRADAEKLLANKP 424
F K LKIL +DD W++AEL G EG +P NY+ + SW+ +R AE+ L ++
Sbjct: 19 FRKGDTLKILGSQDD--WFKAELHGHEGYVPKNYVDRQIPSWFKESASRGSAEETLMSRE 76
Query: 425 EGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
G FLIR S+SSPGDFS+SV+ VQH K
Sbjct: 77 VGAFLIRGSQSSPGDFSISVRHDYDVQHFK 106
Score = 50.4 bits (115), Expect = 4e-05
Identities = 19/41 (46%), Positives = 32/41 (78%)
Frame = +1
Query: 511 KVLRDASSKFFLWVVKFNSLNELVDYHRTASVSRLQDVKLR 633
KV++D S ++LW KF SLN+LVD+++T S+S+ +++ LR
Sbjct: 106 KVMKDKSGHYYLWTEKFTSLNKLVDFYKTTSISKQKEIFLR 146
Score = 35.5 bits (78), Expect = 1.2
Identities = 15/21 (71%), Positives = 18/21 (85%)
Frame = +3
Query: 192 MEALAKHDFTATADDELSFRK 254
MEA K+DF+ TA+DELSFRK
Sbjct: 1 MEARGKYDFSGTAEDELSFRK 21
>UniRef50_Q567F1 Cluster: Zgc:112091; n=2; Euteleostomi|Rep:
Zgc:112091 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 284
Score = 87.0 bits (206), Expect = 4e-16
Identities = 43/90 (47%), Positives = 57/90 (63%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYIQMKNHSWYYGRITRADAEKLLANKP 424
F K LKIL +DD W++AEL G EG +P NY+ + SW+ +R AE+ L ++
Sbjct: 19 FRKGDTLKILGSQDD--WFKAELHGHEGYVPKNYVDRQIPSWFKESASRGSAEETLMSRE 76
Query: 425 EGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
G FLIR S+SSPGDFS+SV+ VQH K
Sbjct: 77 VGAFLIRGSQSSPGDFSISVRHDYDVQHFK 106
Score = 52.8 bits (121), Expect = 8e-06
Identities = 20/42 (47%), Positives = 33/42 (78%)
Frame = +1
Query: 511 KVLRDASSKFFLWVVKFNSLNELVDYHRTASVSRLQDVKLRD 636
KV++D S ++LW KF SLN+LVD+++T S+S+ +++ LRD
Sbjct: 106 KVMKDKSGHYYLWTEKFTSLNKLVDFYKTTSISKQKEIFLRD 147
Score = 35.5 bits (78), Expect = 1.2
Identities = 15/21 (71%), Positives = 18/21 (85%)
Frame = +3
Query: 192 MEALAKHDFTATADDELSFRK 254
MEA K+DF+ TA+DELSFRK
Sbjct: 1 MEARGKYDFSGTAEDELSFRK 21
>UniRef50_UPI0000E478D2 Cluster: PREDICTED: similar to SH2/SH3
adaptor Grb2; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to SH2/SH3 adaptor Grb2 -
Strongylocentrotus purpuratus
Length = 241
Score = 86.2 bits (204), Expect = 7e-16
Identities = 46/94 (48%), Positives = 64/94 (68%), Gaps = 4/94 (4%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYIQM-KNHSWYYGRITRADAEKLLANK 421
F K +VLK++ ED +W A K+GL+P NY+++ K+H WY G+I+R AE+ L +
Sbjct: 21 FKKGEVLKVIKRED-RHWLLAHQGAKQGLVPENYLKIEKSHPWYVGKISRKVAEEYLMSM 79
Query: 422 P-EGGFLIRISESSP--GDFSLSVKCPDGVQHSK 514
P +G F+IR SES+P G+FSLSVK D VQH K
Sbjct: 80 PSDGAFMIRDSESNPDSGNFSLSVKFRDQVQHFK 113
Score = 59.3 bits (137), Expect = 9e-08
Identities = 24/42 (57%), Positives = 33/42 (78%)
Frame = +1
Query: 511 KVLRDASSKFFLWVVKFNSLNELVDYHRTASVSRLQDVKLRD 636
K+L D + K+FLWVVKF S+N+LVDYH+ SVSR Q++ L +
Sbjct: 113 KILTDLAGKYFLWVVKFTSINDLVDYHKDNSVSRTQEIVLNE 154
>UniRef50_O75791 Cluster: GRB2-related adapter protein 2; n=22;
Amniota|Rep: GRB2-related adapter protein 2 - Homo
sapiens (Human)
Length = 330
Score = 86.2 bits (204), Expect = 7e-16
Identities = 41/90 (45%), Positives = 60/90 (66%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYIQMKNHSWYYGRITRADAEKLLANKP 424
F VLKIL+ +++ W++AEL +EG +P N+I ++ W++ ++R AE LL K
Sbjct: 19 FHTGDVLKILSNQEE--WFKAELGSQEGYVPKNFIDIQFPKWFHEGLSRHQAENLLMGKE 76
Query: 425 EGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
G F+IR S+SSPGDFS+SV+ D VQH K
Sbjct: 77 VGFFIIRASQSSPGDFSISVRHEDDVQHFK 106
Score = 55.2 bits (127), Expect = 1e-06
Identities = 24/42 (57%), Positives = 31/42 (73%)
Frame = +1
Query: 511 KVLRDASSKFFLWVVKFNSLNELVDYHRTASVSRLQDVKLRD 636
KV+RD +FLW KF SLN+LVDY+RT S+SR + + LRD
Sbjct: 106 KVMRDNKGNYFLWTEKFPSLNKLVDYYRTNSISRQKQIFLRD 147
Score = 33.1 bits (72), Expect = 6.5
Identities = 14/19 (73%), Positives = 17/19 (89%)
Frame = +3
Query: 192 MEALAKHDFTATADDELSF 248
MEA+AK DFTA+ +DELSF
Sbjct: 1 MEAVAKFDFTASGEDELSF 19
>UniRef50_Q86F73 Cluster: Clone ZZD1053 mRNA sequence; n=1;
Schistosoma japonicum|Rep: Clone ZZD1053 mRNA sequence -
Schistosoma japonicum (Blood fluke)
Length = 234
Score = 82.2 bits (194), Expect = 1e-14
Identities = 45/99 (45%), Positives = 58/99 (58%), Gaps = 9/99 (9%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYIQMKNHSWYYGRITRADAEKLLAN-- 418
F K +LKIL +EDD NWY AE +G+ GLIP NYI M+ H WY +R +AE+ L
Sbjct: 19 FKKGSILKILCVEDDPNWYLAEQEGRTGLIPCNYITMRPHPWYIRHCSRMEAEERLQEVD 78
Query: 419 -------KPEGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
+P+G F++R SE+ FSLSVK V H K
Sbjct: 79 QETAQHLQPDGAFILRQSEADGKGFSLSVKQGCEVLHFK 117
Score = 56.0 bits (129), Expect = 8e-07
Identities = 22/47 (46%), Positives = 36/47 (76%)
Frame = +1
Query: 511 KVLRDASSKFFLWVVKFNSLNELVDYHRTASVSRLQDVKLRDVVPEK 651
KVL+D + K+F W+ +F+S+N+L+D+HR S+SR + + L D+VP K
Sbjct: 117 KVLQDEAGKYFFWISRFDSVNQLIDHHRKTSISRNRLLTLVDLVPSK 163
Score = 35.5 bits (78), Expect = 1.2
Identities = 15/34 (44%), Positives = 23/34 (67%), Gaps = 1/34 (2%)
Frame = +2
Query: 251 KNQVLKILNMEDDMNWYRAEL-DGKEGLIPSNYI 349
+ V++++N DD NW+R DG+ GL PSNY+
Sbjct: 195 RGDVIEVIN-RDDENWWRGRTSDGRCGLFPSNYV 227
>UniRef50_Q5DBN4 Cluster: SJCHGC05332 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC05332 protein - Schistosoma
japonicum (Blood fluke)
Length = 312
Score = 78.6 bits (185), Expect = 1e-13
Identities = 39/97 (40%), Positives = 56/97 (57%), Gaps = 9/97 (9%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYIQMKNHSWYYGRITRADAEKLLAN-- 418
F K L I+ ME+D NWY+A +EG++P+NYI + H WY + +R +AE L
Sbjct: 19 FEKGSTLCIVGMEEDPNWYKARQGNQEGMVPANYISLCPHPWYIPKCSRREAEARLLETD 78
Query: 419 -------KPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
+P+G F++R SE+ PG FS+SVK V H
Sbjct: 79 PNTHRDVQPDGAFVLRQSENDPGHFSISVKEGSSVLH 115
Score = 47.2 bits (107), Expect = 4e-04
Identities = 18/47 (38%), Positives = 31/47 (65%)
Frame = +1
Query: 511 KVLRDASSKFFLWVVKFNSLNELVDYHRTASVSRLQDVKLRDVVPEK 651
++ D S K+++W KF+S+N L+DYHR ++ ++ + LRD V K
Sbjct: 117 RIFFDPSGKYYIWTNKFSSINALIDYHRHQTIYGIKALLLRDCVSSK 163
>UniRef50_A2AAI0 Cluster: Growth factor receptor bound protein 2;
n=3; Eutheria|Rep: Growth factor receptor bound protein
2 - Mus musculus (Mouse)
Length = 71
Score = 78.2 bits (184), Expect = 2e-13
Identities = 31/53 (58%), Positives = 41/53 (77%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYIQMKNHSWYYGRITRADAE 403
F + +LK+LN E D NWY+AEL+GK+G IP NYI+MK H W++G+I RA AE
Sbjct: 19 FKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAE 71
Score = 38.7 bits (86), Expect = 0.13
Identities = 16/21 (76%), Positives = 20/21 (95%)
Frame = +3
Query: 192 MEALAKHDFTATADDELSFRK 254
MEA+AK+DF ATADDELSF++
Sbjct: 1 MEAIAKYDFKATADDELSFKR 21
>UniRef50_Q5BYR6 Cluster: SJCHGC04559 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC04559 protein - Schistosoma
japonicum (Blood fluke)
Length = 206
Score = 75.4 bits (177), Expect = 1e-12
Identities = 42/92 (45%), Positives = 56/92 (60%), Gaps = 9/92 (9%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAELD-GKEGLIPSNYIQMK--------NHSWYYGRITRAD 397
F KN+ LKI+N+ D NW A+ G+ GLIP NY+Q K +H WY+GRI+RA+
Sbjct: 33 FNKNETLKIINIGKDPNWAHAKNTLGETGLIPLNYVQRKESALENIQDHCWYHGRISRAE 92
Query: 398 AEKLLANKPEGGFLIRISESSPGDFSLSVKCP 493
+E LL+ P G FLIR S+ G +L V P
Sbjct: 93 SESLLSGCPIGSFLIRESDLYSGGLTLCVVGP 124
>UniRef50_P41240 Cluster: Tyrosine-protein kinase CSK; n=21;
Deuterostomia|Rep: Tyrosine-protein kinase CSK - Homo
sapiens (Human)
Length = 450
Score = 74.9 bits (176), Expect = 2e-12
Identities = 40/99 (40%), Positives = 58/99 (58%), Gaps = 11/99 (11%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAELD-GKEGLIPSNYIQMKNH----------SWYYGRITR 391
F K VL I+ + D NWY+A+ G+EG+IP+NY+Q + W++G+ITR
Sbjct: 30 FCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKREGVKAGTKLSLMPWFHGKITR 89
Query: 392 ADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
AE+LL G FL+R S + PGD++L V C V+H
Sbjct: 90 EQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEH 128
>UniRef50_O77132 Cluster: Non-receptor protein-tyrosine kinase CSK;
n=1; Hydra vulgaris|Rep: Non-receptor protein-tyrosine
kinase CSK - Hydra attenuata (Hydra) (Hydra vulgaris)
Length = 467
Score = 73.7 bits (173), Expect = 4e-12
Identities = 39/91 (42%), Positives = 55/91 (60%), Gaps = 8/91 (8%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAEL--DGKEGLIPSNYIQMKN----HS--WYYGRITRADA 400
F K +++IL D NWY A+ DG+ GLIP NY+Q + H W++G+ITR A
Sbjct: 43 FKKGDIIEILQSTRDPNWYNAKKVSDGRTGLIPINYVQQRRALHLHEMPWFFGKITREKA 102
Query: 401 EKLLANKPEGGFLIRISESSPGDFSLSVKCP 493
E+LL + G FL+R S + PGD++L V P
Sbjct: 103 EELLTPREVGLFLVRESTNFPGDYTLCVVSP 133
>UniRef50_P42686 Cluster: Tyrosine-protein kinase isoform SRK1;
n=11; Metazoa|Rep: Tyrosine-protein kinase isoform SRK1
- Spongilla lacustris (Freshwater sponge)
Length = 505
Score = 73.3 bits (172), Expect = 5e-12
Identities = 41/96 (42%), Positives = 57/96 (59%), Gaps = 8/96 (8%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAELD--GKEGLIPSNYI----QMKNHSWYYGRITRADAEK 406
F K ++ I++ ++ W+ D GKEG IPSNY+ + W+ G+I R +AEK
Sbjct: 75 FKKGDLMYIISTDEGDWWFARSKDTAGKEGYIPSNYVAEYKSLDAEEWFLGKIKRVEAEK 134
Query: 407 LLANK--PEGGFLIRISESSPGDFSLSVKCPDGVQH 508
+L G FLIR SE++PGDFSLSVK D V+H
Sbjct: 135 MLNQSFNQVGSFLIRDSETTPGDFSLSVKDQDRVRH 170
>UniRef50_P62993-2 Cluster: Isoform GRB3; n=9; Deuterostomia|Rep:
Isoform GRB3 - Homo sapiens (Human)
Length = 176
Score = 72.9 bits (171), Expect = 7e-12
Identities = 34/49 (69%), Positives = 41/49 (83%), Gaps = 2/49 (4%)
Frame = +1
Query: 511 KVLRDASSKFFLWVVKFNSLNELVDYHRTASVSRLQDVKLRDV--VPEK 651
KVLRD + K+FLWVVKFNSLNELVDYHR+ SVSR Q + LRD+ VP++
Sbjct: 68 KVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQ 116
Score = 60.5 bits (140), Expect = 4e-08
Identities = 24/40 (60%), Positives = 31/40 (77%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYIQMKNH 364
F + +LK+LN E D NWY+AEL+GK+G IP NYI+MK H
Sbjct: 19 FKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPH 58
Score = 38.7 bits (86), Expect = 0.13
Identities = 16/21 (76%), Positives = 20/21 (95%)
Frame = +3
Query: 192 MEALAKHDFTATADDELSFRK 254
MEA+AK+DF ATADDELSF++
Sbjct: 1 MEAIAKYDFKATADDELSFKR 21
>UniRef50_Q9Y1Z0 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 485
Score = 55.2 bits (127), Expect(2) = 8e-12
Identities = 24/54 (44%), Positives = 36/54 (66%)
Frame = +2
Query: 347 IQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
+Q+K W++GRI+R DAEKLL G FL+R S++ PGD++L V V++
Sbjct: 102 VQLKTMPWFHGRISREDAEKLLTPPKNGRFLVRESQNYPGDYTLCVSYDGRVEN 155
Score = 37.5 bits (83), Expect(2) = 8e-12
Identities = 19/39 (48%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAEL-DGKEGLIPSNYIQMK 358
F K L I+ D NWY+A DG EG+IP NY+Q K
Sbjct: 27 FKKGDRLVIVAPSKDPNWYKARREDGLEGMIPFNYVQEK 65
>UniRef50_A7T2F6 Cluster: Predicted protein; n=2; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 115
Score = 71.7 bits (168), Expect = 2e-11
Identities = 32/46 (69%), Positives = 39/46 (84%)
Frame = +1
Query: 511 KVLRDASSKFFLWVVKFNSLNELVDYHRTASVSRLQDVKLRDVVPE 648
KVLRD + K+FLWVVKFNSLN+LV+YHRT+SVSR Q + L+DV E
Sbjct: 10 KVLRDGAGKYFLWVVKFNSLNQLVEYHRTSSVSRSQQIFLKDVDSE 55
Score = 34.7 bits (76), Expect = 2.1
Identities = 16/40 (40%), Positives = 25/40 (62%), Gaps = 2/40 (5%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAEL--DGKEGLIPSNYIQMK 358
F K +++L+ EDD NW++ + G+EGL P NY+ K
Sbjct: 77 FKKGNHIEVLDKEDD-NWWKGRVAETGEEGLFPRNYVSSK 115
>UniRef50_A2RQD7 Cluster: Bcr-abl1 e19a2 chimeric protein; n=2; Homo
sapiens|Rep: Bcr-abl1 e19a2 chimeric protein - Homo
sapiens (Human)
Length = 498
Score = 71.7 bits (168), Expect = 2e-11
Identities = 35/90 (38%), Positives = 53/90 (58%), Gaps = 4/90 (4%)
Frame = +2
Query: 251 KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYI----QMKNHSWYYGRITRADAEKLLAN 418
K + L++L + W A+ +G +PSNYI ++ HSWY+G ++R AE LL++
Sbjct: 336 KGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEHLLSS 395
Query: 419 KPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
G FL+R SESSPG S+S++ V H
Sbjct: 396 GINGSFLVRESESSPGQRSISLRYEGRVYH 425
>UniRef50_P00522 Cluster: Tyrosine-protein kinase Abl; n=5;
Eumetazoa|Rep: Tyrosine-protein kinase Abl - Drosophila
melanogaster (Fruit fly)
Length = 1620
Score = 71.7 bits (168), Expect = 2e-11
Identities = 39/98 (39%), Positives = 56/98 (57%), Gaps = 5/98 (5%)
Frame = +2
Query: 251 KNQVLKILNMEDDMNWYRAELD-GKEGLIPSNYI----QMKNHSWYYGRITRADAEKLLA 415
K + ++IL+ W A D G G +PSNY+ ++ HSWY+G I+R AE LL+
Sbjct: 210 KGEQVRILSYNKSGEWCEAHSDSGNVGWVPSNYVTPLNSLEKHSWYHGPISRNAAEYLLS 269
Query: 416 NKPEGGFLIRISESSPGDFSLSVKCPDGVQHSKY*ETP 529
+ G FL+R SESSPG S+S++ V H + E P
Sbjct: 270 SGINGSFLVRESESSPGQRSISLRYEGRVYHYRISEDP 307
>UniRef50_A2RQD6 Cluster: Bcr-abl1 e6a2 chimeric protein; n=10;
Euteleostomi|Rep: Bcr-abl1 e6a2 chimeric protein - Homo
sapiens (Human)
Length = 585
Score = 71.3 bits (167), Expect = 2e-11
Identities = 35/90 (38%), Positives = 53/90 (58%), Gaps = 4/90 (4%)
Frame = +2
Query: 251 KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYI----QMKNHSWYYGRITRADAEKLLAN 418
K + L++L + W A+ +G +PSNYI ++ HSWY+G ++R AE LL++
Sbjct: 423 KGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSS 482
Query: 419 KPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
G FL+R SESSPG S+S++ V H
Sbjct: 483 GINGSFLVRESESSPGQRSISLRYEGRVYH 512
>UniRef50_P10447 Cluster: Tyrosine-protein kinase transforming
protein Abl; n=57; root|Rep: Tyrosine-protein kinase
transforming protein Abl - Feline sarcoma virus (strain
Hardy-Zuckerman 2)
Length = 439
Score = 71.3 bits (167), Expect = 2e-11
Identities = 35/90 (38%), Positives = 53/90 (58%), Gaps = 4/90 (4%)
Frame = +2
Query: 251 KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYI----QMKNHSWYYGRITRADAEKLLAN 418
K + L++L + W A+ +G +PSNYI ++ HSWY+G ++R AE LL++
Sbjct: 33 KGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSS 92
Query: 419 KPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
G FL+R SESSPG S+S++ V H
Sbjct: 93 GINGSFLVRESESSPGQRSISLRYEGRVYH 122
>UniRef50_P42684 Cluster: Tyrosine-protein kinase ABL2; n=38;
Euteleostomi|Rep: Tyrosine-protein kinase ABL2 - Homo
sapiens (Human)
Length = 1182
Score = 71.3 bits (167), Expect = 2e-11
Identities = 34/90 (37%), Positives = 52/90 (57%), Gaps = 4/90 (4%)
Frame = +2
Query: 251 KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYI----QMKNHSWYYGRITRADAEKLLAN 418
K + L++L + W +G +PSNYI ++ HSWY+G ++R+ AE LL++
Sbjct: 130 KGEKLRVLGYNQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSS 189
Query: 419 KPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
G FL+R SESSPG S+S++ V H
Sbjct: 190 LINGSFLVRESESSPGQLSISLRYEGRVYH 219
>UniRef50_P00519 Cluster: Proto-oncogene tyrosine-protein kinase
ABL1; n=35; root|Rep: Proto-oncogene tyrosine-protein
kinase ABL1 - Homo sapiens (Human)
Length = 1130
Score = 71.3 bits (167), Expect = 2e-11
Identities = 35/90 (38%), Positives = 53/90 (58%), Gaps = 4/90 (4%)
Frame = +2
Query: 251 KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYI----QMKNHSWYYGRITRADAEKLLAN 418
K + L++L + W A+ +G +PSNYI ++ HSWY+G ++R AE LL++
Sbjct: 84 KGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSS 143
Query: 419 KPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
G FL+R SESSPG S+S++ V H
Sbjct: 144 GINGSFLVRESESSPGQRSISLRYEGRVYH 173
>UniRef50_UPI00015B4B0F Cluster: PREDICTED: similar to
proto-oncogene tyrosine-protein kinase abl1; n=1;
Nasonia vitripennis|Rep: PREDICTED: similar to
proto-oncogene tyrosine-protein kinase abl1 - Nasonia
vitripennis
Length = 1522
Score = 70.1 bits (164), Expect = 5e-11
Identities = 37/91 (40%), Positives = 54/91 (59%), Gaps = 5/91 (5%)
Frame = +2
Query: 251 KNQVLKILNMEDDMNWYRAELD-GKEGLIPSNYI----QMKNHSWYYGRITRADAEKLLA 415
K + ++IL+ W A G+ G +PSNY+ ++ HSWY+GRI+R AE LL+
Sbjct: 131 KGEQVRILSYNKSGEWCEAHSSSGQVGWVPSNYVTPVNSLEKHSWYHGRISRNAAEYLLS 190
Query: 416 NKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
+ G FL+R SESSPG S+S++ V H
Sbjct: 191 SGINGSFLVRESESSPGQRSISLRYEGRVYH 221
>UniRef50_A2RQD3 Cluster: Bcr-abl1 e13a3 chimeric protein; n=21;
Eumetazoa|Rep: Bcr-abl1 e13a3 chimeric protein - Homo
sapiens (Human)
Length = 235
Score = 69.7 bits (163), Expect = 6e-11
Identities = 34/90 (37%), Positives = 53/90 (58%), Gaps = 4/90 (4%)
Frame = +2
Query: 251 KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYI----QMKNHSWYYGRITRADAEKLLAN 418
+ + L++L + W A+ +G +PSNYI ++ HSWY+G ++R AE LL++
Sbjct: 73 EGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPANSLEKHSWYHGPVSRNAAEYLLSS 132
Query: 419 KPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
G FL+R SESSPG S+S++ V H
Sbjct: 133 GINGSFLVRESESSPGQRSISLRYEGRVYH 162
>UniRef50_UPI0000519AF4 Cluster: PREDICTED: similar to Abl tyrosine
kinase CG4032-PA; n=1; Apis mellifera|Rep: PREDICTED:
similar to Abl tyrosine kinase CG4032-PA - Apis
mellifera
Length = 1439
Score = 69.3 bits (162), Expect = 8e-11
Identities = 37/91 (40%), Positives = 53/91 (58%), Gaps = 5/91 (5%)
Frame = +2
Query: 251 KNQVLKILNMEDDMNWYRAELD-GKEGLIPSNYI----QMKNHSWYYGRITRADAEKLLA 415
K + ++IL+ W A G+ G +PSNY+ ++ HSWY+GRI R AE LL+
Sbjct: 130 KGEQVRILSYNKSGEWCEAHSSTGQVGWVPSNYVTPVNSLEKHSWYHGRICRNAAEYLLS 189
Query: 416 NKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
+ G FL+R SESSPG S+S++ V H
Sbjct: 190 SGINGSFLVRESESSPGQRSISLRYEGRVYH 220
>UniRef50_UPI000058445F Cluster: PREDICTED: similar to SH2/SH3
adaptor protein; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to SH2/SH3 adaptor protein -
Strongylocentrotus purpuratus
Length = 389
Score = 67.3 bits (157), Expect = 3e-10
Identities = 32/68 (47%), Positives = 44/68 (64%), Gaps = 1/68 (1%)
Frame = +2
Query: 314 DGKEGLIPSNYIQMKNHSWYYGRITRADAEKLLANKPEGG-FLIRISESSPGDFSLSVKC 490
D PS+ + + W++GRITR D+EK+L E G FLIR SE+ PGDF++SVK
Sbjct: 273 DEDNSFTPSSSVGFYDRDWFHGRITRQDSEKILGCPGESGLFLIRESETMPGDFAVSVKA 332
Query: 491 PDGVQHSK 514
P+ V+H K
Sbjct: 333 PERVKHFK 340
>UniRef50_Q4S516 Cluster: Chromosome 6 SCAF14737, whole genome
shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 6
SCAF14737, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 393
Score = 55.2 bits (127), Expect(2) = 5e-10
Identities = 29/61 (47%), Positives = 36/61 (59%), Gaps = 1/61 (1%)
Frame = +2
Query: 335 PSNYIQMKNHSWYYGRITRADAEKLLANKP-EGGFLIRISESSPGDFSLSVKCPDGVQHS 511
PS + WYYG++TR AE L + EG FLIR SESSP DFS+S+K +H
Sbjct: 286 PSGSGRFAGKEWYYGKVTRHQAEVALNQRGVEGDFLIRDSESSPHDFSISLKAQSKNKHF 345
Query: 512 K 514
K
Sbjct: 346 K 346
Score = 31.5 bits (68), Expect(2) = 5e-10
Identities = 13/37 (35%), Positives = 25/37 (67%), Gaps = 2/37 (5%)
Frame = +2
Query: 245 F*KNQVLKILNM-EDDMNWYRA-ELDGKEGLIPSNYI 349
F K +V++++ E+D W++ + DG+ GL+P NY+
Sbjct: 223 FEKGEVMEVVEKPENDPEWWKCRKADGQLGLVPKNYV 259
>UniRef50_Q66I04 Cluster: Zgc:92124; n=1; Danio rerio|Rep: Zgc:92124
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 510
Score = 65.7 bits (153), Expect = 1e-09
Identities = 42/93 (45%), Positives = 56/93 (60%), Gaps = 9/93 (9%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAE--LDGKEGLIPSNYIQ----MKNHSWYYGRITRADAEK 406
F K + LKI+ E+ W++A KEG IPSNY+ M+ W+Y ITR DAE+
Sbjct: 82 FKKGEKLKII--EEHGEWWKARSLTTRKEGFIPSNYVAEADTMETEEWFYKDITRKDAER 139
Query: 407 LL---ANKPEGGFLIRISESSPGDFSLSVKCPD 496
L ANKP G +LIR SE+S G +SLS++ D
Sbjct: 140 QLLAPANKP-GSYLIRESETSKGSYSLSIRDVD 171
>UniRef50_Q4RNX3 Cluster: Chromosome 10 SCAF15009, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 10 SCAF15009, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 466
Score = 63.7 bits (148), Expect = 4e-09
Identities = 40/99 (40%), Positives = 60/99 (60%), Gaps = 11/99 (11%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAE--LDGKEGLIPSNYIQM---KNHSWYYGRITRADA-EK 406
F K LKI+N +DD WY AE G+ G IP N+I M + +W++ I+R +A +
Sbjct: 71 FEKGDKLKIIN-KDDSEWYLAESLTTGQRGYIPYNFIAMSTMETEAWFFKNISRNEATRR 129
Query: 407 LLA-NKPEGGFLIRISESSPGDFSLSVK----CPDGVQH 508
L+A +G FL+R SE++PG +SLS++ DGV+H
Sbjct: 130 LMAPGNTQGSFLVRESETTPGSYSLSMRDFDNNGDGVKH 168
>UniRef50_UPI0000E248CE Cluster: PREDICTED: GRB2-related adaptor
protein; n=1; Pan troglodytes|Rep: PREDICTED:
GRB2-related adaptor protein - Pan troglodytes
Length = 164
Score = 62.5 bits (145), Expect = 9e-09
Identities = 27/40 (67%), Positives = 30/40 (75%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYIQMKNH 364
F K LKILNMEDD NWY+AEL G EG IP NYI++K H
Sbjct: 19 FNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIRVKPH 58
>UniRef50_Q6R1Y3 Cluster: Src family kinase; n=6; Fungi/Metazoa
group|Rep: Src family kinase - Asterina miniata (Bat
star) (Patiria miniata)
Length = 563
Score = 62.5 bits (145), Expect = 9e-09
Identities = 38/88 (43%), Positives = 54/88 (61%), Gaps = 8/88 (9%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAE--LDGKEGLIPSNYIQ----MKNHSWYYGRITRADAEK 406
F K ++L I N + D NW+ A L +EG +P NYI+ ++ W++ ++TR +AEK
Sbjct: 137 FRKGEILIITN-KTDPNWWLATSMLTKREGYVPRNYIEPADVLQAEDWFFEKMTRKEAEK 195
Query: 407 LL--ANKPEGGFLIRISESSPGDFSLSV 484
L A G FLIR SE+SPG +SLSV
Sbjct: 196 QLQLAGNSRGTFLIRGSETSPGAYSLSV 223
>UniRef50_P07947 Cluster: Proto-oncogene tyrosine-protein kinase
Yes; n=422; root|Rep: Proto-oncogene tyrosine-protein
kinase Yes - Homo sapiens (Human)
Length = 543
Score = 60.1 bits (139), Expect = 5e-08
Identities = 35/94 (37%), Positives = 55/94 (58%), Gaps = 7/94 (7%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWY-RAELDGKEGLIPSNYI----QMKNHSWYYGRITRADAEKL 409
F K + +I+N + W R+ GK G IPSNY+ ++ WY+G++ R DAE+L
Sbjct: 112 FKKGERFQIINNTEGDWWEARSIATGKNGYIPSNYVAPADSIQAEEWYFGKMGRKDAERL 171
Query: 410 LAN--KPEGGFLIRISESSPGDFSLSVKCPDGVQ 505
L N G FL+R SE++ G +SLS++ D ++
Sbjct: 172 LLNPGNQRGIFLVRESETTKGAYSLSIRDWDEIR 205
>UniRef50_Q4RL31 Cluster: Chromosome undetermined SCAF15024, whole
genome shotgun sequence; n=8; Euteleostomi|Rep:
Chromosome undetermined SCAF15024, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 511
Score = 58.4 bits (135), Expect = 2e-07
Identities = 39/93 (41%), Positives = 56/93 (60%), Gaps = 9/93 (9%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAEL--DGKEGLIPSNYI----QMKNHSWYYGRITRADAEK 406
F K + +KIL E+ W+RA+ +EG IPSNY+ M+ W++ I+R DAE+
Sbjct: 37 FKKGERMKIL--EERGEWWRAKSLSTNREGFIPSNYVGQADTMETEDWFFKDISRKDAER 94
Query: 407 LL---ANKPEGGFLIRISESSPGDFSLSVKCPD 496
L AN+ G +LIR SE++ G FSLSV+ D
Sbjct: 95 QLLAPANRA-GSYLIRESETAKGSFSLSVRDVD 126
>UniRef50_Q70DV1 Cluster: Src tyrosine kinase; n=1; Schistosoma
mansoni|Rep: Src tyrosine kinase - Schistosoma mansoni
(Blood fluke)
Length = 647
Score = 58.0 bits (134), Expect = 2e-07
Identities = 32/94 (34%), Positives = 52/94 (55%), Gaps = 8/94 (8%)
Frame = +2
Query: 251 KNQVLKILNMEDDMNWYRAEL--DGKEGLIPSNYI----QMKNHSWYYGRITRADAEKLL 412
K Q+ IL+ +W+ AE G G +P N++ ++++ WY+G + R +AE L
Sbjct: 178 KGQIFNILD-NSHCDWWYAECVSTGNRGYVPKNHLAAVTSLESNEWYFGELKRIEAEHYL 236
Query: 413 A--NKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
G FL+RISES ++SLSV+ + V+H
Sbjct: 237 QLPGNDHGSFLVRISESQSSEYSLSVREENTVKH 270
>UniRef50_A2AQ87 Cluster: Novel protein (Possible orthologue of
human Src homology 2 domain containing F (SHF)); n=10;
Euteleostomi|Rep: Novel protein (Possible orthologue of
human Src homology 2 domain containing F (SHF)) - Mus
musculus (Mouse)
Length = 446
Score = 57.6 bits (133), Expect = 3e-07
Identities = 26/56 (46%), Positives = 35/56 (62%)
Frame = +2
Query: 347 IQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
+ ++N WY+G I+R DAE LL E +L+R SE+S DFSLS+K G H K
Sbjct: 339 LPLENQVWYHGAISRTDAENLLRLCKEASYLVRNSETSKNDFSLSLKSSQGFMHMK 394
>UniRef50_Q95PW9 Cluster: Temporarily assigned gene name protein 22,
isoform a; n=3; Caenorhabditis|Rep: Temporarily assigned
gene name protein 22, isoform a - Caenorhabditis elegans
Length = 395
Score = 57.6 bits (133), Expect = 3e-07
Identities = 27/57 (47%), Positives = 40/57 (70%)
Frame = +2
Query: 347 IQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSKY 517
I M+ WY+GRI+R AE LL + EG FL+R SES+PGD S+S++ G++ +K+
Sbjct: 294 IPMEQQPWYFGRISRERAEDLLLHGREGEFLVRDSESNPGDLSISMR---GIERNKH 347
>UniRef50_Q7M4L6 Cluster: Shb-like adapter protein, Shf; n=21;
Amniota|Rep: Shb-like adapter protein, Shf - Homo
sapiens (Human)
Length = 480
Score = 57.6 bits (133), Expect = 3e-07
Identities = 26/56 (46%), Positives = 35/56 (62%)
Frame = +2
Query: 347 IQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
+ ++N WY+G I+R DAE LL E +L+R SE+S DFSLS+K G H K
Sbjct: 373 LPLENQVWYHGAISRTDAENLLRLCKEASYLVRNSETSKNDFSLSLKSSQGFMHMK 428
>UniRef50_Q573B4 Cluster: Proto-oncogene tyrosine-protein kinase
LCK; n=11; Coelomata|Rep: Proto-oncogene
tyrosine-protein kinase LCK - Homo sapiens (Human)
Length = 516
Score = 57.6 bits (133), Expect = 3e-07
Identities = 37/89 (41%), Positives = 52/89 (58%), Gaps = 8/89 (8%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAE--LDGKEGLIPSNYIQMKN----HSWYYGRITRADAEK 406
F K + L+IL E W++A+ G+EG IP N++ N W++ ++R DAE+
Sbjct: 140 FEKGEQLRIL--EQSGEWWKAQSLTTGQEGFIPFNFVAKANSLEPEPWFFKNLSRKDAER 197
Query: 407 -LLA-NKPEGGFLIRISESSPGDFSLSVK 487
LLA G FLIR SES+ G FSLSV+
Sbjct: 198 QLLAPGNTHGSFLIRESESTAGSFSLSVR 226
>UniRef50_UPI0000D9EE2E Cluster: PREDICTED: similar to src homology
2 domain-containing transforming protein D; n=1; Macaca
mulatta|Rep: PREDICTED: similar to src homology 2
domain-containing transforming protein D - Macaca
mulatta
Length = 221
Score = 57.2 bits (132), Expect = 4e-07
Identities = 25/55 (45%), Positives = 37/55 (67%)
Frame = +2
Query: 362 HSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSKY*ET 526
+ W++G + RADAE LL+ EG +L+R+SE+SP D SLS++ G H K+ T
Sbjct: 119 YGWFHGPLNRADAESLLSLCKEGSYLVRLSETSPQDCSLSLRSSQGFLHLKFART 173
>UniRef50_Q4S9J7 Cluster: Chromosome undetermined SCAF14696, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF14696, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 131
Score = 56.8 bits (131), Expect = 5e-07
Identities = 23/41 (56%), Positives = 29/41 (70%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYIQMKNHS 367
F K VLKI NMEDD NWY AEL ++G +P NYI ++ H+
Sbjct: 19 FNKGDVLKITNMEDDPNWYTAELHNRKGFVPKNYINLRPHA 59
>UniRef50_Q5BWZ4 Cluster: SJCHGC04657 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC04657 protein - Schistosoma
japonicum (Blood fluke)
Length = 153
Score = 56.8 bits (131), Expect = 5e-07
Identities = 21/47 (44%), Positives = 36/47 (76%)
Frame = +2
Query: 347 IQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVK 487
+ ++ W++ +TR++AE+L+ N+PEG FL+R SE+ P DFSL++K
Sbjct: 48 LPLEEQPWFHPSLTRSEAEELIRNEPEGSFLVRPSETCPNDFSLTIK 94
>UniRef50_A7SE08 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 193
Score = 56.8 bits (131), Expect = 5e-07
Identities = 25/44 (56%), Positives = 33/44 (75%)
Frame = +1
Query: 511 KVLRDASSKFFLWVVKFNSLNELVDYHRTASVSRLQDVKLRDVV 642
KV RD K++LW KF SLN+LVD+HR ASVSR Q + L+D++
Sbjct: 89 KVFRDTDRKYYLWNTKFLSLNKLVDHHREASVSRSQHIVLKDMM 132
Score = 56.4 bits (130), Expect = 6e-07
Identities = 22/40 (55%), Positives = 29/40 (72%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYIQMKNH 364
F K +L +L+M+ D NWY+AE DG+EG IP YI+MK H
Sbjct: 19 FAKGSILNVLDMDQDKNWYKAEQDGREGWIPKTYIEMKPH 58
>UniRef50_Q96IW2 Cluster: SH2 domain-containing adapter protein D;
n=13; Mammalia|Rep: SH2 domain-containing adapter
protein D - Homo sapiens (Human)
Length = 340
Score = 56.4 bits (130), Expect = 6e-07
Identities = 24/60 (40%), Positives = 39/60 (65%)
Frame = +2
Query: 347 IQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSKY*ET 526
+ ++ W++G + RADAE LL+ EG +L+R+SE++P D SLS++ G H K+ T
Sbjct: 233 LPLEKQPWFHGPLNRADAESLLSLCKEGSYLVRLSETNPQDCSLSLRSSQGFLHLKFART 292
>UniRef50_UPI0000F1FB23 Cluster: PREDICTED: similar to tyrosine
protein kinase BTK; n=1; Danio rerio|Rep: PREDICTED:
similar to tyrosine protein kinase BTK - Danio rerio
Length = 596
Score = 56.0 bits (129), Expect = 8e-07
Identities = 33/85 (38%), Positives = 49/85 (57%), Gaps = 7/85 (8%)
Frame = +2
Query: 251 KNQVLKILNMEDDMNWYRA-ELDGKEGLIPSNYI-----QMKNHSWYYGRITRADAEKLL 412
K++ +L + D NW++A + GKEG IPSNYI ++ + WY I R+ AE LL
Sbjct: 196 KDEEYTLLEISDP-NWFKAKDKYGKEGYIPSNYIVQALNGLEKYDWYCKNINRSQAENLL 254
Query: 413 -ANKPEGGFLIRISESSPGDFSLSV 484
+GGFL+R S G +++SV
Sbjct: 255 KTENKDGGFLVRDSGKFTGKYTVSV 279
>UniRef50_Q7QGU0 Cluster: ENSANGP00000018199; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000018199 - Anopheles gambiae
str. PEST
Length = 710
Score = 56.0 bits (129), Expect = 8e-07
Identities = 25/56 (44%), Positives = 35/56 (62%)
Frame = +2
Query: 347 IQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
I + WY+G I+R DAEK+L EG FL+R SES+ D+SL++K G H +
Sbjct: 602 IPLDRQGWYHGSISRIDAEKILRPLSEGSFLVRNSESTRQDYSLTLKSAKGFMHMR 657
>UniRef50_Q17BH3 Cluster: Putative uncharacterized protein; n=1; Aedes
aegypti|Rep: Putative uncharacterized protein - Aedes
aegypti (Yellowfever mosquito)
Length = 1044
Score = 56.0 bits (129), Expect = 8e-07
Identities = 30/81 (37%), Positives = 46/81 (56%)
Frame = +2
Query: 272 LNMEDDMNWYRAELDGKEGLIPSNYIQMKNHSWYYGRITRADAEKLLANKPEGGFLIRIS 451
L++ + N RA ++ + IP + WY+G I+R DAEK+L EG FL+R S
Sbjct: 916 LDLGLNFNTIRANIELIDATIP-----LDRQGWYHGSISRIDAEKILRPLGEGSFLVRNS 970
Query: 452 ESSPGDFSLSVKCPDGVQHSK 514
ES+ D+SL++K G H +
Sbjct: 971 ESTRQDYSLTLKSAKGFMHMR 991
>UniRef50_P03949 Cluster: Tyrosine-protein kinase abl-1; n=5;
Caenorhabditis|Rep: Tyrosine-protein kinase abl-1 -
Caenorhabditis elegans
Length = 1224
Score = 56.0 bits (129), Expect = 8e-07
Identities = 27/68 (39%), Positives = 45/68 (66%), Gaps = 4/68 (5%)
Frame = +2
Query: 317 GKEGLIPSNYIQMKN----HSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSV 484
G+ G +PSN+I N ++WY+G+I+R+D+E +L + G FL+R SE+S G +++SV
Sbjct: 173 GEIGWVPSNFIAPYNSLDKYTWYHGKISRSDSEAILGSGITGSFLVRESETSIGQYTISV 232
Query: 485 KCPDGVQH 508
+ V H
Sbjct: 233 RHDGRVFH 240
>UniRef50_Q0PDJ5 Cluster: Protein tyrosine kinase CSK; n=1; Monosiga
ovata|Rep: Protein tyrosine kinase CSK - Monosiga ovata
Length = 468
Score = 55.2 bits (127), Expect = 1e-06
Identities = 35/108 (32%), Positives = 54/108 (50%), Gaps = 20/108 (18%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRA-ELDGKEGLIPSNYIQMKNHS------------------ 367
F K +L I N +D NW+ + G+ G+IP+NY+++
Sbjct: 40 FKKGDILTIENPTEDPNWWLVRDKTGRTGMIPANYVELIGSDTKKTGTLPRDASGQLIPM 99
Query: 368 -WYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
W++G+I+R AE LL + +G FL+R S PGD++L V D V H
Sbjct: 100 PWFHGKISRELAESLLMPREDGLFLVRESAHFPGDYTLCVCFQDQVDH 147
>UniRef50_Q8BZ27 Cluster: Adult female vagina cDNA, RIKEN
full-length enriched library, clone:9930020J04
product:similar to epidermal growth factor-receptor-
binding protein GRB-4; n=5; Eutheria|Rep: Adult female
vagina cDNA, RIKEN full-length enriched library,
clone:9930020J04 product:similar to epidermal growth
factor-receptor- binding protein GRB-4 - Mus musculus
(Mouse)
Length = 123
Score = 54.8 bits (126), Expect = 2e-06
Identities = 29/61 (47%), Positives = 37/61 (60%), Gaps = 1/61 (1%)
Frame = +2
Query: 335 PSNYIQMKNHSWYYGRITRADAEKLLANKP-EGGFLIRISESSPGDFSLSVKCPDGVQHS 511
PS + + WYYG++TR AE L + EG FLIR SESSP DFS+S+K +H
Sbjct: 17 PSLTGKFAGNPWYYGKVTRHQAEMALNERGHEGDFLIRDSESSPNDFSVSLKAQGKNKHF 76
Query: 512 K 514
K
Sbjct: 77 K 77
>UniRef50_O43639 Cluster: Cytoplasmic protein NCK2; n=54;
Euteleostomi|Rep: Cytoplasmic protein NCK2 - Homo
sapiens (Human)
Length = 380
Score = 54.8 bits (126), Expect = 2e-06
Identities = 29/61 (47%), Positives = 36/61 (59%), Gaps = 1/61 (1%)
Frame = +2
Query: 335 PSNYIQMKNHSWYYGRITRADAEKLLANKP-EGGFLIRISESSPGDFSLSVKCPDGVQHS 511
PS+ + WYYG +TR AE L + EG FLIR SESSP DFS+S+K +H
Sbjct: 274 PSSSGRFAGREWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNKHF 333
Query: 512 K 514
K
Sbjct: 334 K 334
>UniRef50_P42685 Cluster: Tyrosine-protein kinase FRK; n=27;
Fungi/Metazoa group|Rep: Tyrosine-protein kinase FRK -
Homo sapiens (Human)
Length = 505
Score = 54.4 bits (125), Expect = 2e-06
Identities = 31/68 (45%), Positives = 41/68 (60%), Gaps = 6/68 (8%)
Frame = +2
Query: 323 EGLIPSNYI----QMKNHSWYYGRITRADAEK--LLANKPEGGFLIRISESSPGDFSLSV 484
+G IPSNY+ ++ W++G I R+DAEK L + G FLIR SES G+FSLSV
Sbjct: 97 QGYIPSNYVAEDRSLQAEPWFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSV 156
Query: 485 KCPDGVQH 508
V+H
Sbjct: 157 LDGAVVKH 164
>UniRef50_Q06187 Cluster: Tyrosine-protein kinase BTK; n=54;
Gnathostomata|Rep: Tyrosine-protein kinase BTK - Homo
sapiens (Human)
Length = 659
Score = 54.4 bits (125), Expect = 2e-06
Identities = 30/75 (40%), Positives = 49/75 (65%), Gaps = 7/75 (9%)
Frame = +2
Query: 281 EDDMNWYRA-ELDGKEGLIPSNYI-----QMKNHSWYYGRITRADAEKLLANK-PEGGFL 439
E ++ W+RA + +G+EG IPSNY+ ++ + WY +TR+ AE+LL + EGGF+
Sbjct: 246 ESNLPWWRARDKNGQEGYIPSNYVTEAEDSIEMYEWYSKHMTRSQAEQLLKQEGKEGGFI 305
Query: 440 IRISESSPGDFSLSV 484
+R S S G +++SV
Sbjct: 306 VRDS-SKAGKYTVSV 319
>UniRef50_UPI0000E497E3 Cluster: PREDICTED: similar to
protein-tyrosine phosphatase; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to protein-tyrosine
phosphatase - Strongylocentrotus purpuratus
Length = 533
Score = 53.6 bits (123), Expect = 4e-06
Identities = 26/59 (44%), Positives = 35/59 (59%), Gaps = 1/59 (1%)
Frame = +2
Query: 335 PSNYIQMKNHSWYYGRITRADAEKLLANKPEGG-FLIRISESSPGDFSLSVKCPDGVQH 508
P N N W++G IT +AEK L +K + G +L+R S S PGD+ LSV+ D V H
Sbjct: 101 PLNCADPTNERWFHGHITGKEAEKSLVDKGKNGSYLVRESHSKPGDYVLSVRTEDKVTH 159
Score = 46.0 bits (104), Expect = 9e-04
Identities = 24/55 (43%), Positives = 35/55 (63%), Gaps = 1/55 (1%)
Frame = +2
Query: 353 MKNHSWYYGRITRADAEKLLANKP-EGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
M + W++ I+ +AE+LL N +G FL R S+S+PGDF+LSV+ V H K
Sbjct: 1 MASRRWFHPNISGMEAEQLLLNNGFDGCFLCRPSKSNPGDFTLSVRRNGEVTHIK 55
>UniRef50_UPI00006A1C31 Cluster: UPI00006A1C31 related cluster; n=1;
Xenopus tropicalis|Rep: UPI00006A1C31 UniRef100 entry -
Xenopus tropicalis
Length = 419
Score = 53.6 bits (123), Expect = 4e-06
Identities = 25/49 (51%), Positives = 34/49 (69%)
Frame = +2
Query: 353 MKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDG 499
+++H+WY+G + R DAE+LL + G FLIR S SSPGD+ LS C G
Sbjct: 10 LRSHAWYHGPLPRQDAERLLVS--NGDFLIRDSISSPGDYVLSCFCAGG 56
>UniRef50_UPI00006A1C30 Cluster: UPI00006A1C30 related cluster; n=1;
Xenopus tropicalis|Rep: UPI00006A1C30 UniRef100 entry -
Xenopus tropicalis
Length = 514
Score = 53.6 bits (123), Expect = 4e-06
Identities = 25/49 (51%), Positives = 34/49 (69%)
Frame = +2
Query: 353 MKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDG 499
+++H+WY+G + R DAE+LL + G FLIR S SSPGD+ LS C G
Sbjct: 23 LRSHAWYHGPLPRQDAERLLVS--NGDFLIRDSISSPGDYVLSCFCAGG 69
>UniRef50_Q0PIN0 Cluster: Bam32; n=1; Branchiostoma belcheri
tsingtauense|Rep: Bam32 - Branchiostoma belcheri
tsingtauense
Length = 250
Score = 53.6 bits (123), Expect = 4e-06
Identities = 24/55 (43%), Positives = 38/55 (69%), Gaps = 1/55 (1%)
Frame = +2
Query: 347 IQMKNHSWYYGRITRADAEKLL-ANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
++++ WY+G ++R AE LL AN +G +L+R S + G++SLSVKC D V+H
Sbjct: 7 LEVEQLDWYHGDLSRHMAEALLMANAEDGSYLLRSSATRVGEYSLSVKCKDSVKH 61
>UniRef50_Q9H6Q3 Cluster: Src-like-adapter 2; n=21;
Euteleostomi|Rep: Src-like-adapter 2 - Homo sapiens
(Human)
Length = 261
Score = 53.6 bits (123), Expect = 4e-06
Identities = 28/74 (37%), Positives = 45/74 (60%), Gaps = 4/74 (5%)
Frame = +2
Query: 278 MEDDMNWYR--AELDGKEGLIPSNYIQMKNHSWYYGRITRADAEK--LLANKPEGGFLIR 445
+ +D +W+ +E+ G+E IPS ++ +H W Y ++R AE+ LL P G FLIR
Sbjct: 62 VSEDGDWWTVLSEVSGREYNIPSVHVAKVSHGWLYEGLSREKAEELLLLPGNPGGAFLIR 121
Query: 446 ISESSPGDFSLSVK 487
S++ G +SLSV+
Sbjct: 122 ESQTRRGSYSLSVR 135
>UniRef50_UPI0000D554A0 Cluster: PREDICTED: similar to CG11146-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG11146-PA - Tribolium castaneum
Length = 871
Score = 53.2 bits (122), Expect = 6e-06
Identities = 23/56 (41%), Positives = 35/56 (62%)
Frame = +2
Query: 347 IQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
+ ++ W++G ITR +AE +L EG FL+R SES+ D+SLS+K G H +
Sbjct: 763 LPLEKQGWFHGAITRVEAENVLRMLREGSFLVRNSESTKQDYSLSLKSARGFMHMR 818
>UniRef50_Q1ED32 Cluster: Zgc:136231; n=1; Danio rerio|Rep:
Zgc:136231 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 222
Score = 53.2 bits (122), Expect = 6e-06
Identities = 34/91 (37%), Positives = 54/91 (59%), Gaps = 9/91 (9%)
Frame = +2
Query: 242 QF*KNQVLKILNMEDDMNWYRAE--LDGKEGLIPSNYIQ----MKNHSWYYGRITRADAE 403
QF K L+I+ +++ W+ A+ + G EG IPS Y+ ++ W++ + R D E
Sbjct: 58 QFKKGDRLRII--KENGEWWLAKSLVTGYEGFIPSTYVARAQTLQVERWFFKDMNRRDTE 115
Query: 404 KLL---ANKPEGGFLIRISESSPGDFSLSVK 487
+LL NKP G FL+R SE++ G FSLS++
Sbjct: 116 RLLLAPGNKP-GSFLVRESETTKGAFSLSIR 145
>UniRef50_P05433 Cluster: P47(GAG-CRK) protein; n=3; root|Rep:
P47(GAG-CRK) protein - Avian sarcoma virus (strain CT10)
Length = 440
Score = 53.2 bits (122), Expect = 6e-06
Identities = 27/64 (42%), Positives = 34/64 (53%)
Frame = +2
Query: 317 GKEGLIPSNYIQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPD 496
G L+ + SWY+GR++R DA LL + G FL+R S S PGDF LSV
Sbjct: 231 GGAALMAGQFDSEDRGSWYWGRLSRGDAVSLLQGQRHGTFLVRDSGSIPGDFVLSVSESS 290
Query: 497 GVQH 508
V H
Sbjct: 291 RVSH 294
Score = 34.3 bits (75), Expect = 2.8
Identities = 13/36 (36%), Positives = 22/36 (61%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYIQ 352
F K +LKI + ++ W ++DGK G+IP Y++
Sbjct: 389 FKKGDILKIRDKPEEQWWNAEDMDGKRGMIPVPYVE 424
>UniRef50_P00521 Cluster: Tyrosine-protein kinase transforming
protein Abl; n=15; root|Rep: Tyrosine-protein kinase
transforming protein Abl - Abelson murine leukemia virus
Length = 746
Score = 53.2 bits (122), Expect = 6e-06
Identities = 24/52 (46%), Positives = 35/52 (67%)
Frame = +2
Query: 353 MKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
++ HSWY+G ++R AE LL++ G FL+R SESSPG S+S++ V H
Sbjct: 8 LEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYH 59
>UniRef50_Q9BL77 Cluster: C-terminal src kinase protein 1; n=2;
Caenorhabditis|Rep: C-terminal src kinase protein 1 -
Caenorhabditis elegans
Length = 539
Score = 52.8 bits (121), Expect = 8e-06
Identities = 25/64 (39%), Positives = 39/64 (60%), Gaps = 1/64 (1%)
Frame = +2
Query: 338 SNYIQMKNHS-WYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
S++ NH W++ I+R + EKLL KP+G FL+R S + PGDF+L + V+H +
Sbjct: 140 SHHSTAANHQPWFHSMISRENTEKLLRGKPDGTFLVRESTNFPGDFTLCMSFHGKVEHYR 199
Query: 515 Y*ET 526
+T
Sbjct: 200 IEQT 203
>UniRef50_P08631 Cluster: Tyrosine-protein kinase HCK; n=32;
Euteleostomi|Rep: Tyrosine-protein kinase HCK - Homo
sapiens (Human)
Length = 526
Score = 52.8 bits (121), Expect = 8e-06
Identities = 31/78 (39%), Positives = 47/78 (60%), Gaps = 8/78 (10%)
Frame = +2
Query: 278 MEDDMNWYRAE--LDGKEGLIPSNYI----QMKNHSWYYGRITRADAEK-LLA-NKPEGG 433
+E+ W++A KEG IPSNY+ ++ W++ I+R DAE+ LLA G
Sbjct: 108 LEESGEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGS 167
Query: 434 FLIRISESSPGDFSLSVK 487
F+IR SE++ G +SLSV+
Sbjct: 168 FMIRDSETTKGSYSLSVR 185
>UniRef50_UPI00015B496D Cluster: PREDICTED: similar to conserved
hypothetical protein; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to conserved hypothetical protein -
Nasonia vitripennis
Length = 1182
Score = 52.4 bits (120), Expect = 1e-05
Identities = 23/56 (41%), Positives = 35/56 (62%)
Frame = +2
Query: 347 IQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
+ ++ WY+G ITR +AE +L EG +L+R SES+ D+SLS+K G H +
Sbjct: 1074 LPLERQGWYHGSITRIEAEAVLRLLREGSYLVRNSESTKQDYSLSLKSARGFMHMR 1129
>UniRef50_UPI0000E49A1C Cluster: PREDICTED: similar to Growth factor
receptor-bound protein 2; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to Growth factor
receptor-bound protein 2 - Strongylocentrotus purpuratus
Length = 176
Score = 52.4 bits (120), Expect = 1e-05
Identities = 25/48 (52%), Positives = 33/48 (68%)
Frame = +2
Query: 365 SWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
+W++ ITR +AE LL + G FL+R SESS G +SLSVK + VQH
Sbjct: 13 AWFFPTITRKNAELLLMQERNGAFLVRRSESSEGLYSLSVKYNESVQH 60
Score = 51.6 bits (118), Expect = 2e-05
Identities = 22/43 (51%), Positives = 31/43 (72%)
Frame = +1
Query: 511 KVLRDASSKFFLWVVKFNSLNELVDYHRTASVSRLQDVKLRDV 639
++L+D + KF LW+VKF SL+ LVDY+RT SV+R V + V
Sbjct: 62 RILQDTAGKFHLWIVKFPSLDALVDYYRTTSVTRENQVSTQSV 104
>UniRef50_UPI0000DB713D Cluster: PREDICTED: similar to CG11146-PA
isoform 2; n=1; Apis mellifera|Rep: PREDICTED: similar to
CG11146-PA isoform 2 - Apis mellifera
Length = 1122
Score = 52.4 bits (120), Expect = 1e-05
Identities = 23/56 (41%), Positives = 35/56 (62%)
Frame = +2
Query: 347 IQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
+ ++ WY+G ITR +AE +L EG +L+R SES+ D+SLS+K G H +
Sbjct: 1014 LPLERQGWYHGSITRIEAEAVLRLLREGSYLVRNSESTKQDYSLSLKSARGFMHMR 1069
>UniRef50_UPI0000D56E93 Cluster: PREDICTED: similar to SH2 domain
containing 4B; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to SH2 domain containing 4B - Tribolium
castaneum
Length = 412
Score = 52.4 bits (120), Expect = 1e-05
Identities = 28/74 (37%), Positives = 47/74 (63%), Gaps = 1/74 (1%)
Frame = +2
Query: 290 MNWYRAELDGK-EGLIPSNYIQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPG 466
+ WY++ K GL SN ++ SW++G ITR++AEKLL ++P G FL+R+SE G
Sbjct: 286 VEWYKSHERPKWTGLDRSNNVE----SWFHGLITRSEAEKLLLDRPYGSFLVRLSERIWG 341
Query: 467 DFSLSVKCPDGVQH 508
+++S + + +H
Sbjct: 342 -YAISYRAKEKCKH 354
>UniRef50_Q4RNL0 Cluster: Chromosome 21 SCAF15012, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 21
SCAF15012, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 509
Score = 52.4 bits (120), Expect = 1e-05
Identities = 33/84 (39%), Positives = 47/84 (55%), Gaps = 7/84 (8%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAELD-GKEGLIPSNYI----QMKNHSWYYGRITRADAEK- 406
F K + I+N + W LD G G IPSNY+ ++ WY+G++ R DAE+
Sbjct: 22 FRKGEKFHIINNTEGDWWEARSLDTGNSGYIPSNYVAPVDSIQAEEWYFGKMGRKDAERQ 81
Query: 407 LLAN-KPEGGFLIRISESSPGDFS 475
LLA+ G FLIR SE++ G+ S
Sbjct: 82 LLAHGNQRGTFLIRESETTKGEHS 105
>UniRef50_Q7JVF1 Cluster: LP02169p; n=2; Sophophora|Rep: LP02169p -
Drosophila melanogaster (Fruit fly)
Length = 342
Score = 52.4 bits (120), Expect = 1e-05
Identities = 22/53 (41%), Positives = 35/53 (66%)
Frame = +2
Query: 350 QMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
+M N WY+G I+R D+++ L++KP G FL+R SE+S F+LS + + H
Sbjct: 183 EMLNQVWYWGEISRRDSQRQLSDKPTGSFLVRDSETSGSQFTLSFRIVNVTLH 235
>UniRef50_P42680 Cluster: Tyrosine-protein kinase Tec; n=86;
Coelomata|Rep: Tyrosine-protein kinase Tec - Homo
sapiens (Human)
Length = 631
Score = 52.4 bits (120), Expect = 1e-05
Identities = 30/76 (39%), Positives = 49/76 (64%), Gaps = 8/76 (10%)
Frame = +2
Query: 281 EDDMNWYRA-ELDGKEGLIPSNYIQMKN------HSWYYGRITRADAEKLLANK-PEGGF 436
++D++W+RA + G EG IPSNY+ K + WY + R+ AE+LL ++ EGGF
Sbjct: 211 KNDVHWWRARDKYGNEGYIPSNYVTGKKSNNLDQYEWYCRNMNRSKAEQLLRSEDKEGGF 270
Query: 437 LIRISESSPGDFSLSV 484
++R S S PG +++S+
Sbjct: 271 MVRDS-SQPGLYTVSL 285
>UniRef50_UPI000155BA92 Cluster: PREDICTED: similar to Fyn-related
kinase, partial; n=1; Ornithorhynchus anatinus|Rep:
PREDICTED: similar to Fyn-related kinase, partial -
Ornithorhynchus anatinus
Length = 186
Score = 52.0 bits (119), Expect = 1e-05
Identities = 28/60 (46%), Positives = 38/60 (63%), Gaps = 7/60 (11%)
Frame = +2
Query: 323 EGLIPSNYI----QMKNHSWYYGRITRADAEKLL---ANKPEGGFLIRISESSPGDFSLS 481
+G +P+NY+ ++ W++G I R DAEK L N+P G FLIR SES GD+SLS
Sbjct: 128 QGYVPANYLAKDQSLQAEQWFFGAIKRVDAEKQLLYSGNRP-GAFLIRESESQKGDYSLS 186
>UniRef50_UPI00015A58A4 Cluster: UPI00015A58A4 related cluster; n=1;
Danio rerio|Rep: UPI00015A58A4 UniRef100 entry - Danio
rerio
Length = 426
Score = 52.0 bits (119), Expect = 1e-05
Identities = 27/74 (36%), Positives = 48/74 (64%), Gaps = 8/74 (10%)
Frame = +2
Query: 287 DMNWYRAE-LDGKEGLIPSNYI------QMKNHSWYYGRITRADAEKLLANK-PEGGFLI 442
++NWY+A +GK+G IPSNY+ +++ W+ + R AE+LL + EGGF++
Sbjct: 254 EVNWYKARNKEGKQGYIPSNYVTEKASDKLEQFIWFSKNVNRNKAEELLRKEGKEGGFMV 313
Query: 443 RISESSPGDFSLSV 484
R+S S+ G +++S+
Sbjct: 314 RLS-SNTGTYTVSL 326
>UniRef50_Q4SR72 Cluster: Chromosome 11 SCAF14528, whole genome
shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 11
SCAF14528, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 236
Score = 52.0 bits (119), Expect = 1e-05
Identities = 32/90 (35%), Positives = 46/90 (51%), Gaps = 8/90 (8%)
Frame = +2
Query: 263 LKILNMEDDMNWYRAELDGKEGLIPSNYIQMKNHSWYYGRITRADAEKL--LANKPEGGF 436
L IL+ + D R+ G E IP+ Y H+W + ++R+ A +L L N G F
Sbjct: 42 LTILSDDGDFLMVRSATTGLESYIPTTYAAKVTHTWLFAGVSRSKAVELLMLPNNRNGAF 101
Query: 437 LIRISESSPGDFSLSV------KCPDGVQH 508
LIR SE+S +SLS+ C D V+H
Sbjct: 102 LIRESETSADCYSLSILRRSGSPCMDSVKH 131
>UniRef50_Q9VYM1 Cluster: CG11146-PA; n=2; Coelomata|Rep: CG11146-PA -
Drosophila melanogaster (Fruit fly)
Length = 1416
Score = 52.0 bits (119), Expect = 1e-05
Identities = 24/56 (42%), Positives = 33/56 (58%)
Frame = +2
Query: 347 IQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
I ++ WY+G ITR +AE L EG FL+R ES+ D+SLS+K G H +
Sbjct: 1309 IPLERQGWYHGAITRIEAETTLRPLSEGSFLVRNCESTKQDYSLSLKGAKGFMHMR 1364
>UniRef50_P00528 Cluster: Tyrosine-protein kinase Src64B; n=6;
Endopterygota|Rep: Tyrosine-protein kinase Src64B -
Drosophila melanogaster (Fruit fly)
Length = 552
Score = 52.0 bits (119), Expect = 1e-05
Identities = 29/89 (32%), Positives = 51/89 (57%), Gaps = 8/89 (8%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAE--LDGKEGLIPSNYI----QMKNHSWYYGRITRADAEK 406
F K +++++ + + +W+R +EGLIP N++ + + W++ + R +A+K
Sbjct: 116 FMKGDRMEVID-DTESDWWRVVNLTTRQEGLIPLNFVAEERSVNSEDWFFENVLRKEADK 174
Query: 407 LLA--NKPEGGFLIRISESSPGDFSLSVK 487
LL P G FL+R SE +P +SLSVK
Sbjct: 175 LLLAEENPRGTFLVRPSEHNPNGYSLSVK 203
>UniRef50_Q98TP5 Cluster: C-Src protein-tyrosine kinase; n=5;
Euteleostomi|Rep: C-Src protein-tyrosine kinase -
Platichthys flesus (European flounder)
Length = 120
Score = 51.2 bits (117), Expect = 2e-05
Identities = 22/47 (46%), Positives = 31/47 (65%)
Frame = +2
Query: 368 WYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
W++G+ITR AE+LL G FL+R S + PGD++L V C V+H
Sbjct: 18 WFHGKITRNQAEQLLCPPETGLFLVRESTNFPGDYTLCVSCDGKVEH 64
>UniRef50_Q5ZM15 Cluster: Putative uncharacterized protein; n=3;
Gallus gallus|Rep: Putative uncharacterized protein -
Gallus gallus (Chicken)
Length = 431
Score = 50.8 bits (116), Expect = 3e-05
Identities = 25/51 (49%), Positives = 32/51 (62%), Gaps = 1/51 (1%)
Frame = +2
Query: 335 PSNYIQMKNHSWYYGRITRADAEKLLANKPE-GGFLIRISESSPGDFSLSV 484
P N + WY+G +T +AEKLL K + G FL+R S+S PGDF LSV
Sbjct: 99 PLNCQDPTSERWYHGHLTGKEAEKLLTEKGKPGSFLVRESQSKPGDFVLSV 149
Score = 47.6 bits (108), Expect = 3e-04
Identities = 24/50 (48%), Positives = 33/50 (66%), Gaps = 1/50 (2%)
Frame = +2
Query: 368 WYYGRITRADAEKLLANKP-EGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
W++ I+ +AEKLL + G FL R S+S+PGDF+LSV+ D V H K
Sbjct: 4 WFHPNISGIEAEKLLLTRGVHGSFLARPSKSNPGDFTLSVRRNDEVTHIK 53
>UniRef50_Q4TEC1 Cluster: Chromosome undetermined SCAF5507, whole
genome shotgun sequence; n=3; Tetraodontidae|Rep:
Chromosome undetermined SCAF5507, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1116
Score = 50.8 bits (116), Expect = 3e-05
Identities = 35/106 (33%), Positives = 55/106 (51%), Gaps = 12/106 (11%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWY---RAELDGK---EGLIPSNYIQM----KNHSWYYGRITRA 394
F + + ++L+ DD W+ R + G+ GL+P NY+ + W++G + R
Sbjct: 20 FREGDLFRVLSRRDD--WWSVRRIDASGRVLDSGLVPGNYLAPAESGQTQPWFFGTLNRL 77
Query: 395 DAEK-LLA-NKPEGGFLIRISESSPGDFSLSVKCPDGVQHSKY*ET 526
A+ LLA EG FLIR+SE + LSV+ D V+H K +T
Sbjct: 78 QAQSHLLAPENSEGAFLIRVSEKDNVGYVLSVRSGDQVKHYKVLQT 123
Score = 46.8 bits (106), Expect = 5e-04
Identities = 22/49 (44%), Positives = 30/49 (61%), Gaps = 2/49 (4%)
Frame = +2
Query: 368 WYYGRITRADAEKLL--ANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
WYYG I R AEKLL + +G FL+RISES ++++S + V H
Sbjct: 250 WYYGNINRVKAEKLLLASQNKDGSFLVRISESHSDEYTISARSEGKVFH 298
>UniRef50_P51451 Cluster: Tyrosine-protein kinase BLK; n=5;
Euteleostomi|Rep: Tyrosine-protein kinase BLK - Homo
sapiens (Human)
Length = 505
Score = 50.8 bits (116), Expect = 3e-05
Identities = 35/89 (39%), Positives = 52/89 (58%), Gaps = 7/89 (7%)
Frame = +2
Query: 242 QF*KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYI----QMKNHSWYYGRITRADAEK- 406
Q K + L++L D R+ + G+EG +PSN++ ++ W++ R +AE+
Sbjct: 78 QMLKGEKLQVLKGTGDWWLARSLVTGREGYVPSNFVARVESLEMERWFFRSQGRKEAERQ 137
Query: 407 LLA--NKPEGGFLIRISESSPGDFSLSVK 487
LLA NK G FLIR SE++ G FSLSVK
Sbjct: 138 LLAPINKA-GSFLIRESETNKGAFSLSVK 165
>UniRef50_UPI0000F1D8DB Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 321
Score = 50.0 bits (114), Expect = 5e-05
Identities = 21/57 (36%), Positives = 36/57 (63%)
Frame = +2
Query: 347 IQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSKY 517
+ ++ WY+G +TR++AE LL E +L+R S++S D+SLS++ G H K+
Sbjct: 214 LPLEKQVWYHGALTRSEAESLLTLCKECSYLVRKSQTSRNDYSLSLRSCHGFMHMKF 270
>UniRef50_UPI0000D55B96 Cluster: PREDICTED: similar to
Tyrosine-protein kinase Src64B (Dsrc64) isoform 2; n=1;
Tribolium castaneum|Rep: PREDICTED: similar to
Tyrosine-protein kinase Src64B (Dsrc64) isoform 2 -
Tribolium castaneum
Length = 473
Score = 50.0 bits (114), Expect = 5e-05
Identities = 24/61 (39%), Positives = 38/61 (62%), Gaps = 6/61 (9%)
Frame = +2
Query: 323 EGLIPSNYI----QMKNHSWYYGRITRADAEKLLA--NKPEGGFLIRISESSPGDFSLSV 484
+G IP N++ +++ W++ ++R +AEKLL P G FL+R SE +P +SLSV
Sbjct: 116 QGYIPGNFVAAELSVESEDWFFENVSRKEAEKLLLAEENPRGTFLVRPSEHNPNGYSLSV 175
Query: 485 K 487
K
Sbjct: 176 K 176
>UniRef50_UPI000065F097 Cluster: Hematopoietic SH2 domain-containing
protein (Hematopoietic SH2 protein) (Adaptor in
lymphocytes of unknown function X).; n=1; Takifugu
rubripes|Rep: Hematopoietic SH2 domain-containing
protein (Hematopoietic SH2 protein) (Adaptor in
lymphocytes of unknown function X). - Takifugu rubripes
Length = 266
Score = 50.0 bits (114), Expect = 5e-05
Identities = 24/47 (51%), Positives = 33/47 (70%)
Frame = +2
Query: 368 WYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
W++G ITR AE+LLA +P G FLIR+SES G ++LS + D +H
Sbjct: 23 WFHGIITRKAAEELLAPRPRGCFLIRVSESRAG-YTLSYRAEDRCKH 68
>UniRef50_Q29G65 Cluster: GA20849-PA; n=1; Drosophila
pseudoobscura|Rep: GA20849-PA - Drosophila pseudoobscura
(Fruit fly)
Length = 891
Score = 50.0 bits (114), Expect = 5e-05
Identities = 22/57 (38%), Positives = 38/57 (66%)
Frame = +2
Query: 338 SNYIQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
S+ ++K++ WY+G ++ AEK+L+N+P+G F++R S FSLS K + V+H
Sbjct: 736 SSIEKVKDYGWYWGPLSGEAAEKVLSNEPDGSFIVRDSSDDHYIFSLSFKLNNCVRH 792
>UniRef50_Q15464 Cluster: SH2 domain-containing adapter protein B;
n=29; Euteleostomi|Rep: SH2 domain-containing adapter
protein B - Homo sapiens (Human)
Length = 509
Score = 50.0 bits (114), Expect = 5e-05
Identities = 23/60 (38%), Positives = 36/60 (60%)
Frame = +2
Query: 347 IQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSKY*ET 526
+ ++ WY+G I+R DAE LL E +L+R S++S D+SLS++ G H K +T
Sbjct: 403 VPLEKQIWYHGAISRGDAENLLRLCKECSYLVRNSQTSKHDYSLSLRSNQGFMHMKLAKT 462
>UniRef50_Q06124 Cluster: Tyrosine-protein phosphatase non-receptor
type 11; n=73; Bilateria|Rep: Tyrosine-protein
phosphatase non-receptor type 11 - Homo sapiens (Human)
Length = 597
Score = 50.0 bits (114), Expect = 5e-05
Identities = 24/55 (43%), Positives = 34/55 (61%), Gaps = 1/55 (1%)
Frame = +2
Query: 335 PSNYIQMKNHSWYYGRITRADAEKLLANKPE-GGFLIRISESSPGDFSLSVKCPD 496
P N + W++G ++ +AEKLL K + G FL+R S+S PGDF LSV+ D
Sbjct: 101 PLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGD 155
Score = 48.0 bits (109), Expect = 2e-04
Identities = 24/55 (43%), Positives = 34/55 (61%), Gaps = 1/55 (1%)
Frame = +2
Query: 353 MKNHSWYYGRITRADAEKLLANKP-EGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
M + W++ IT +AE LL + +G FL R S+S+PGDF+LSV+ V H K
Sbjct: 1 MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIK 55
>UniRef50_P29349 Cluster: Tyrosine-protein phosphatase corkscrew;
n=15; Eumetazoa|Rep: Tyrosine-protein phosphatase
corkscrew - Drosophila melanogaster (Fruit fly)
Length = 845
Score = 50.0 bits (114), Expect = 5e-05
Identities = 22/48 (45%), Positives = 33/48 (68%), Gaps = 1/48 (2%)
Frame = +2
Query: 368 WYYGRITRADAEKLLANKPEGG-FLIRISESSPGDFSLSVKCPDGVQH 508
W++G ++ +AEKL+ + + G FL+R S+S PGDF LSV+ D V H
Sbjct: 111 WFHGNLSGKEAEKLILERGKNGSFLVRESQSKPGDFVLSVRTDDKVTH 158
Score = 46.0 bits (104), Expect = 9e-04
Identities = 23/55 (41%), Positives = 35/55 (63%), Gaps = 1/55 (1%)
Frame = +2
Query: 353 MKNHSWYYGRITRADAEKLLANKP-EGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
M + W++ I+ +AEKLL + +G FL R+S S+PG F+LSV+ + V H K
Sbjct: 1 MSSRRWFHPTISGIEAEKLLQEQGFDGSFLARLSSSNPGAFTLSVRRGNEVTHIK 55
>UniRef50_Q9VPU1 Cluster: CG3727-PB, isoform B; n=9;
Endopterygota|Rep: CG3727-PB, isoform B - Drosophila
melanogaster (Fruit fly)
Length = 548
Score = 49.6 bits (113), Expect = 7e-05
Identities = 23/49 (46%), Positives = 34/49 (69%), Gaps = 1/49 (2%)
Frame = +2
Query: 365 SWYYGRITRADAEKLL-ANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
SWYYG ITR+ + +L + +G FLIR SE++ GD+S+S+K P +H
Sbjct: 447 SWYYGAITRSQCDTVLNGHGHDGDFLIRDSETNMGDYSVSLKAPGRNKH 495
>UniRef50_UPI00015B6424 Cluster: PREDICTED: similar to CG8146-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
CG8146-PA - Nasonia vitripennis
Length = 944
Score = 49.2 bits (112), Expect = 9e-05
Identities = 21/53 (39%), Positives = 35/53 (66%)
Frame = +2
Query: 350 QMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
++K++ WY+G I+ AEK+L+N+P+G F++R S FSLS + V+H
Sbjct: 753 KVKDYGWYWGPISGEAAEKILSNEPDGSFIVRDSSDDHYIFSLSFRLNSCVRH 805
>UniRef50_UPI0000DB7BD4 Cluster: PREDICTED: similar to Suppressor of
Cytokine Signaling at 16D CG8146-PA, partial; n=1; Apis
mellifera|Rep: PREDICTED: similar to Suppressor of
Cytokine Signaling at 16D CG8146-PA, partial - Apis
mellifera
Length = 804
Score = 49.2 bits (112), Expect = 9e-05
Identities = 21/53 (39%), Positives = 35/53 (66%)
Frame = +2
Query: 350 QMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
++K++ WY+G I+ AEK+L+N+P+G F++R S FSLS + V+H
Sbjct: 614 KVKDYGWYWGPISGEAAEKILSNEPDGSFIVRDSSDDHYIFSLSFRLNSCVRH 666
>UniRef50_Q7YZX2 Cluster: Bruton's tyrosine kinase-like protein;
n=1; Suberites domuncula|Rep: Bruton's tyrosine
kinase-like protein - Suberites domuncula (Sponge)
Length = 700
Score = 49.2 bits (112), Expect = 9e-05
Identities = 28/91 (30%), Positives = 52/91 (57%), Gaps = 5/91 (5%)
Frame = +2
Query: 251 KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYIQ---MKNHSWYYGRITRADAEKLLANK 421
K Q + + + + W + G EG IPSNY++ + + W++ +++R AE +L +
Sbjct: 276 KGQRVTVFDATREFWWRARDEQGSEGYIPSNYVKKMGLDSEEWFFPQLSRTRAENILKGE 335
Query: 422 -PEGGFLIRISESSPGDFSLSVKCPDG-VQH 508
EGGF++R + S ++LS+ C +G V+H
Sbjct: 336 GREGGFVVR-NSSRENMYTLSI-CHEGQVRH 364
>UniRef50_A0NEZ5 Cluster: ENSANGP00000031260; n=4; Culicidae|Rep:
ENSANGP00000031260 - Anopheles gambiae str. PEST
Length = 491
Score = 49.2 bits (112), Expect = 9e-05
Identities = 22/53 (41%), Positives = 33/53 (62%)
Frame = +2
Query: 350 QMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
+++ WY+G IT AEK+L+N+P+G FL+R S FSL+ K V+H
Sbjct: 313 KVQEFGWYWGPITSEGAEKILSNEPDGSFLVRDSSDDHYIFSLTFKLNGTVRH 365
>UniRef50_Q60I21 Cluster: TEC family protein tyrosine kinase; n=1;
Eptatretus burgeri|Rep: TEC family protein tyrosine
kinase - Eptatretus burgeri (Inshore hagfish)
Length = 636
Score = 48.8 bits (111), Expect = 1e-04
Identities = 33/77 (42%), Positives = 46/77 (59%), Gaps = 10/77 (12%)
Frame = +2
Query: 284 DDMN--WYRAE-LDGKEGLIPSNYI------QMKNHSWYYGRITRADAEKLLANK-PEGG 433
DD N W+RA+ +G+EGLIPS Y+ ++ + W+ ITRA AE+LL EG
Sbjct: 224 DDKNPHWWRAQDEEGREGLIPSTYVYPLTRFDLEQNRWFCKDITRAKAEQLLRQAGSEGS 283
Query: 434 FLIRISESSPGDFSLSV 484
FL+R S S G ++SV
Sbjct: 284 FLVRES-SQVGKLTVSV 299
>UniRef50_Q8T6F8 Cluster: SRC-1; n=3; Caenorhabditis|Rep: SRC-1 -
Caenorhabditis elegans
Length = 533
Score = 48.8 bits (111), Expect = 1e-04
Identities = 28/91 (30%), Positives = 51/91 (56%), Gaps = 7/91 (7%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWY-RAELDGKEGLIPSNYIQ----MKNHSWYYGRITRADAEKL 409
F K + +L+ + WY R + G+ G +P N++ +++ WY G+I R AE+L
Sbjct: 92 FQKGDAMYLLDHSNCDWWYVRHQRTGQTGYVPRNFVAKQQTIESEEWYAGKIPRNRAERL 151
Query: 410 LANK--PEGGFLIRISESSPGDFSLSVKCPD 496
+ + P+G FLIR E+ +F+L+++ D
Sbjct: 152 VLSSHLPKGTFLIREREADTREFALTIRDTD 182
>UniRef50_O18683 Cluster: P60 protein; n=2; Sophophora|Rep: P60
protein - Drosophila melanogaster (Fruit fly)
Length = 506
Score = 48.8 bits (111), Expect = 1e-04
Identities = 19/52 (36%), Positives = 36/52 (69%)
Frame = +2
Query: 329 LIPSNYIQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSV 484
L+ N +++ WY+GRI+R +A+ +L KP+G FL+R + S G+++L++
Sbjct: 19 LVDPNEDELRMAPWYWGRISREEAKSILHGKPDGSFLVRDALSMKGEYTLTL 70
Score = 37.9 bits (84), Expect = 0.23
Identities = 22/63 (34%), Positives = 31/63 (49%)
Frame = +2
Query: 338 SNYIQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSKY 517
SN W R +AE++L P G FLIR ++ G ++LS+ C + VQH
Sbjct: 327 SNQPHSNEALWLLKDAKRRNAEEMLKGAPSGTFLIRARDA--GHYALSIACKNIVQHCLI 384
Query: 518 *ET 526
ET
Sbjct: 385 YET 387
>UniRef50_A1L2D2 Cluster: Zgc:158798; n=7; Clupeocephala|Rep:
Zgc:158798 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 391
Score = 48.4 bits (110), Expect = 2e-04
Identities = 21/57 (36%), Positives = 36/57 (63%)
Frame = +2
Query: 347 IQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSKY 517
+ ++ WY+G ++R++AE LL E +L+R SE+S D+SLS++ G H K+
Sbjct: 284 LPLEKQVWYHGSLSRSEAESLLTLCKECSYLVRNSETSRLDYSLSLRSCQGFMHMKF 340
>UniRef50_Q9VX18 Cluster: CG8146-PA; n=1; Drosophila melanogaster|Rep:
CG8146-PA - Drosophila melanogaster (Fruit fly)
Length = 1039
Score = 48.4 bits (110), Expect = 2e-04
Identities = 21/57 (36%), Positives = 38/57 (66%)
Frame = +2
Query: 338 SNYIQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
S+ ++K++ WY+G ++ AEK+L+++P+G F++R S FSLS K + V+H
Sbjct: 858 SSIEKVKDYGWYWGPLSSEAAEKVLSSEPDGSFIVRDSSDDHYIFSLSFKLNNCVRH 914
>UniRef50_O75815 Cluster: Breast cancer anti-estrogen resistance
protein 3; n=34; Euteleostomi|Rep: Breast cancer
anti-estrogen resistance protein 3 - Homo sapiens
(Human)
Length = 825
Score = 48.4 bits (110), Expect = 2e-04
Identities = 23/54 (42%), Positives = 36/54 (66%)
Frame = +2
Query: 353 MKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
+++H+WY+GRI R +E L+ +G FL+R S SSPG+F L+ + + QH K
Sbjct: 149 LRSHAWYHGRIPRQVSENLVQR--DGDFLVRDSLSSPGNFVLTCQWKNLAQHFK 200
>UniRef50_UPI00006A0536 Cluster: Nck1-prov protein.; n=1; Xenopus
tropicalis|Rep: Nck1-prov protein. - Xenopus tropicalis
Length = 345
Score = 39.9 bits (89), Expect(2) = 2e-04
Identities = 21/43 (48%), Positives = 26/43 (60%), Gaps = 1/43 (2%)
Frame = +2
Query: 335 PSNYIQMKNHSWYYGRITRADAEKLLANK-PEGGFLIRISESS 460
PS + + WYYG++TR AE L + EG FLIR SESS
Sbjct: 271 PSASGRFAGNQWYYGKVTRHQAEMALNERGNEGDFLIRDSESS 313
Score = 27.9 bits (59), Expect(2) = 2e-04
Identities = 12/37 (32%), Positives = 23/37 (62%), Gaps = 2/37 (5%)
Frame = +2
Query: 245 F*KNQVLKILNM-EDDMNWYRA-ELDGKEGLIPSNYI 349
F K +V+ ++ E+D W++ + +G GL+P NY+
Sbjct: 211 FEKGEVMDVIEKPENDPEWWKCRKSNGLVGLVPKNYV 247
>UniRef50_UPI0000D559E9 Cluster: PREDICTED: similar to CG8146-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG8146-PA - Tribolium castaneum
Length = 687
Score = 48.0 bits (109), Expect = 2e-04
Identities = 20/53 (37%), Positives = 35/53 (66%)
Frame = +2
Query: 350 QMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
++K++ WY+G + AEK+L+N+P+G F++R S FSL+ K + V+H
Sbjct: 473 RVKDYGWYWGPLPSEVAEKILSNEPDGSFIVRDSSDDHYIFSLTFKLNNCVRH 525
>UniRef50_UPI00006A214E Cluster: SH2 domain-containing adapter
protein E.; n=1; Xenopus tropicalis|Rep: SH2
domain-containing adapter protein E. - Xenopus
tropicalis
Length = 437
Score = 48.0 bits (109), Expect = 2e-04
Identities = 20/54 (37%), Positives = 32/54 (59%)
Frame = +2
Query: 347 IQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
+ ++ SWY+G +TR AE LL + PE +L+R S S +S+++K G H
Sbjct: 330 VPLEKQSWYHGSVTRDQAESLLDSCPEASYLLRNSGSGNSKYSIALKTSQGCVH 383
>UniRef50_Q7T0U4 Cluster: MGC68984 protein; n=2; Xenopus|Rep:
MGC68984 protein - Xenopus laevis (African clawed frog)
Length = 266
Score = 48.0 bits (109), Expect = 2e-04
Identities = 27/77 (35%), Positives = 42/77 (54%), Gaps = 2/77 (2%)
Frame = +2
Query: 263 LKILNMEDDMNWYRAELDGKEGLIPSNYIQMKNHSWYYGRITRADAEKLLA--NKPEGGF 436
L IL+ + D + G+E +P+NY+ + W Y I R AE+LL + G F
Sbjct: 54 LNILSEDGDWLKVSSASTGQECYLPTNYVAKVCNRWLYKGINREKAEELLMVNSNRSGSF 113
Query: 437 LIRISESSPGDFSLSVK 487
LIR SE+ G ++LS++
Sbjct: 114 LIRESETRSGSYTLSIR 130
>UniRef50_Q17MF5 Cluster: Tyrosine-protein kinase; n=2;
Culicidae|Rep: Tyrosine-protein kinase - Aedes aegypti
(Yellowfever mosquito)
Length = 747
Score = 48.0 bits (109), Expect = 2e-04
Identities = 21/47 (44%), Positives = 32/47 (68%)
Frame = +2
Query: 368 WYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
W++GRI R +AE LL + +G FL+R S + PGD++L V + V+H
Sbjct: 378 WFHGRIKREEAENLLKPREDGLFLVRESTNFPGDYTLCVCFNEKVEH 424
>UniRef50_Q5BXT3 Cluster: SJCHGC03955 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC03955 protein - Schistosoma
japonicum (Blood fluke)
Length = 190
Score = 47.6 bits (108), Expect = 3e-04
Identities = 21/50 (42%), Positives = 32/50 (64%)
Frame = +2
Query: 359 NHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
++SWY+G ++R E LL + G FL+R SES+PG S++V+ V H
Sbjct: 75 SYSWYHGAVSRQAGEHLLRSGITGSFLVRASESAPGQLSVTVRHLGRVYH 124
>UniRef50_Q16IP4 Cluster: Phosphatidylinositol 3-kinase regulatory
subunit; n=1; Aedes aegypti|Rep: Phosphatidylinositol
3-kinase regulatory subunit - Aedes aegypti (Yellowfever
mosquito)
Length = 568
Score = 47.6 bits (108), Expect = 3e-04
Identities = 25/56 (44%), Positives = 32/56 (57%)
Frame = +2
Query: 365 SWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSKY*ETPR 532
+W R DAEK LA+KP G F+IR S G ++LS+KC D V H +T R
Sbjct: 465 TWLVPTFNRTDAEKELASKPNGTFVIR--PGSGGPYALSIKCNDTVNHCIIQQTDR 518
Score = 41.1 bits (92), Expect = 0.025
Identities = 14/40 (35%), Positives = 28/40 (70%)
Frame = +2
Query: 368 WYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVK 487
WY+G I R + ++ + + P+G FL+R + S G+++L++K
Sbjct: 186 WYWGNINRDEVKEKMTDVPDGSFLVRDASSGNGEYTLTLK 225
>UniRef50_UPI00015B564A Cluster: PREDICTED: similar to CRK protein;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to CRK
protein - Nasonia vitripennis
Length = 298
Score = 47.2 bits (107), Expect = 4e-04
Identities = 25/54 (46%), Positives = 32/54 (59%), Gaps = 1/54 (1%)
Frame = +2
Query: 350 QMKNHSWYYGRITRADAEKLLANKPEGG-FLIRISESSPGDFSLSVKCPDGVQH 508
Q SWY+G ++R DA LL ++ EGG FL+R S S GDF L V+ V H
Sbjct: 7 QNDKSSWYFGAMSRQDASDLLMSEKEGGVFLVRDSISIQGDFVLCVREDSKVSH 60
>UniRef50_UPI0000F2B3BE Cluster: PREDICTED: similar to
Src-like-adaptor 2; n=1; Monodelphis domestica|Rep:
PREDICTED: similar to Src-like-adaptor 2 - Monodelphis
domestica
Length = 310
Score = 47.2 bits (107), Expect = 4e-04
Identities = 26/77 (33%), Positives = 44/77 (57%), Gaps = 4/77 (5%)
Frame = +2
Query: 269 ILNMEDDMNWYR--AELDGKEGLIPSNYIQMKNHSWYYGRITRADAEK--LLANKPEGGF 436
++ + D+ W+R +E KE ++PS+++ + W Y + R AE LL + G F
Sbjct: 99 LIIISDNGEWWRVLSEATSKEYVVPSSHVARISQGWLYEGLNREKAEDLLLLPSNHGGSF 158
Query: 437 LIRISESSPGDFSLSVK 487
LIR S++ G +SLSV+
Sbjct: 159 LIRESQTRRGAYSLSVR 175
>UniRef50_UPI0000D57699 Cluster: PREDICTED: similar to CG18247-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG18247-PA - Tribolium castaneum
Length = 725
Score = 47.2 bits (107), Expect = 4e-04
Identities = 23/49 (46%), Positives = 31/49 (63%), Gaps = 2/49 (4%)
Frame = +2
Query: 368 WYYGRITRADAEKLLAN--KPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
WY+G+++R E LL +P+G FL+R S SS GDF LSV + V H
Sbjct: 9 WYHGKLSREATENLLKEEGRPDGSFLVRESNSSTGDFVLSVLHNNEVSH 57
>UniRef50_UPI00005A0859 Cluster: PREDICTED: similar to SH2 domain
containing 4B; n=1; Canis lupus familiaris|Rep:
PREDICTED: similar to SH2 domain containing 4B - Canis
familiaris
Length = 488
Score = 47.2 bits (107), Expect = 4e-04
Identities = 22/47 (46%), Positives = 31/47 (65%)
Frame = +2
Query: 368 WYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
W++G I+R DAE LL N EG FL+R+SE G ++LS + G +H
Sbjct: 382 WFHGIISREDAEDLLENMTEGAFLVRVSEKIWG-YTLSYRLQKGFKH 427
>UniRef50_Q6DEM2 Cluster: V-crk sarcoma virus CT10 oncogene homolog;
n=5; Clupeocephala|Rep: V-crk sarcoma virus CT10
oncogene homolog - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 311
Score = 47.2 bits (107), Expect = 4e-04
Identities = 23/56 (41%), Positives = 32/56 (57%)
Frame = +2
Query: 341 NYIQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
N+ SWY+GR++R +A LL + G FL+R S + PGD+ LSV V H
Sbjct: 4 NFDSEDRGSWYWGRLSRQEAVSLLQGQRHGVFLVRDSITIPGDYVLSVSENSKVSH 59
>UniRef50_Q6NP28 Cluster: LP09923p; n=6; Endopterygota|Rep: LP09923p
- Drosophila melanogaster (Fruit fly)
Length = 847
Score = 47.2 bits (107), Expect = 4e-04
Identities = 21/54 (38%), Positives = 34/54 (62%)
Frame = +2
Query: 347 IQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
+++ W++G ITR +AE LL + +G FL+R S + PGD++L V V+H
Sbjct: 472 VKLNAMPWFHGSITRDEAEHLLQPREDGLFLVRESTNFPGDYTLCVCFQSKVEH 525
>UniRef50_Q5SQS7 Cluster: Novel SH2 domain-containing protein; n=28;
Euteleostomi|Rep: Novel SH2 domain-containing protein -
Homo sapiens (Human)
Length = 431
Score = 47.2 bits (107), Expect = 4e-04
Identities = 22/47 (46%), Positives = 31/47 (65%)
Frame = +2
Query: 368 WYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
W++G I+R DAE LL N EG FL+R+SE G ++LS + G +H
Sbjct: 325 WFHGIISREDAEALLENMTEGAFLVRVSEKIWG-YTLSYRLQKGFKH 370
>UniRef50_Q5VZ18 Cluster: SH2 domain-containing adapter protein E;
n=16; Euteleostomi|Rep: SH2 domain-containing adapter
protein E - Homo sapiens (Human)
Length = 495
Score = 47.2 bits (107), Expect = 4e-04
Identities = 23/65 (35%), Positives = 35/65 (53%)
Frame = +2
Query: 314 DGKEGLIPSNYIQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCP 493
D EG + ++ WY+G I+RA+AE L E G+L+R SES +S+++K
Sbjct: 377 DHSEGEKVDPGLPLEKQPWYHGAISRAEAESRLQPCKEAGYLVRNSESGNSRYSIALKTS 436
Query: 494 DGVQH 508
G H
Sbjct: 437 QGCVH 441
>UniRef50_UPI0000519A8B Cluster: PREDICTED: similar to
Phosphatidylinositol 3-kinase regulatory subunit alpha
(PI3-kinase p85-subunit alpha) (PtdIns-3-kinase
p85-alpha) (PI3K); n=2; Apocrita|Rep: PREDICTED: similar
to Phosphatidylinositol 3-kinase regulatory subunit alpha
(PI3-kinase p85-subunit alpha) (PtdIns-3-kinase
p85-alpha) (PI3K) - Apis mellifera
Length = 1256
Score = 46.8 bits (106), Expect = 5e-04
Identities = 20/48 (41%), Positives = 33/48 (68%)
Frame = +2
Query: 365 SWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
+W Y +R+DA+++LA++P+G FLIR S + G ++LS+ C V H
Sbjct: 1127 TWLYLECSRSDADRILADRPDGTFLIRTSRT--GQYALSIMCNGTVNH 1172
Score = 40.7 bits (91), Expect = 0.033
Identities = 14/45 (31%), Positives = 30/45 (66%)
Frame = +2
Query: 353 MKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVK 487
++ WY+G ITR + + + + P+G FL+R + S G+++L+++
Sbjct: 834 LQEAEWYWGDITRDEVNEKMIDSPDGTFLVRDASSKGGEYTLTLR 878
>UniRef50_UPI00015A4B5A Cluster: protein tyrosine phosphatase,
non-receptor type 11 (Noonan syndrome 1); n=1; Danio
rerio|Rep: protein tyrosine phosphatase, non-receptor
type 11 (Noonan syndrome 1) - Danio rerio
Length = 564
Score = 46.8 bits (106), Expect = 5e-04
Identities = 23/52 (44%), Positives = 33/52 (63%), Gaps = 1/52 (1%)
Frame = +2
Query: 362 HSWYYGRITRADAEKLLANKP-EGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
+ W++ IT +AE LL + +G FL R S+S+PGDF+LSV+ V H K
Sbjct: 4 YRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIK 55
>UniRef50_Q85476 Cluster: (recovered insertion mutant of B77) src;
n=4; root|Rep: (recovered insertion mutant of B77) src -
Rous sarcoma virus
Length = 285
Score = 46.8 bits (106), Expect = 5e-04
Identities = 21/41 (51%), Positives = 30/41 (73%), Gaps = 2/41 (4%)
Frame = +2
Query: 368 WYYGRITRADAEKLLAN--KPEGGFLIRISESSPGDFSLSV 484
WY+G+ITR ++E+LL N P G FL+R SE++ G + LSV
Sbjct: 229 WYFGKITRRESERLLLNPENPRGTFLVRKSETTKGAYCLSV 269
>UniRef50_Q4S6Q5 Cluster: Chromosome undetermined SCAF14724, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF14724,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 803
Score = 46.8 bits (106), Expect = 5e-04
Identities = 23/55 (41%), Positives = 35/55 (63%)
Frame = +2
Query: 350 QMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
++++H+WY+G I R AE L+ +G FLIR S SSPG + L+ + + QH K
Sbjct: 30 ELRSHAWYHGAIPRQVAENLVQR--DGDFLIRDSLSSPGSYVLTSQWRNTAQHFK 82
>UniRef50_Q13882 Cluster: Tyrosine-protein kinase 6; n=11;
Mammalia|Rep: Tyrosine-protein kinase 6 - Homo sapiens
(Human)
Length = 451
Score = 46.8 bits (106), Expect = 5e-04
Identities = 24/70 (34%), Positives = 40/70 (57%), Gaps = 6/70 (8%)
Frame = +2
Query: 323 EGLIPSNYIQ----MKNHSWYYGRITRADAEKLLA--NKPEGGFLIRISESSPGDFSLSV 484
+G +P NY+ +++ W++G I+R++A + L G FLIR+SE D+ LSV
Sbjct: 59 QGYVPHNYLAERETVESEPWFFGCISRSEAVRRLQAEGNATGAFLIRVSEKPSADYVLSV 118
Query: 485 KCPDGVQHSK 514
+ V+H K
Sbjct: 119 RDTQAVRHYK 128
>UniRef50_Q9UN19 Cluster: Dual adapter for phosphotyrosine and
3-phosphotyrosine and 3- phosphoinositide; n=25;
Euteleostomi|Rep: Dual adapter for phosphotyrosine and
3-phosphotyrosine and 3- phosphoinositide - Homo sapiens
(Human)
Length = 280
Score = 46.8 bits (106), Expect = 5e-04
Identities = 22/53 (41%), Positives = 35/53 (66%), Gaps = 1/53 (1%)
Frame = +2
Query: 353 MKNHSWYYGRITRADAEKLL-ANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
+++ WY+G +TR AE LL +N +G +L+R S + G +SLSV+ D V+H
Sbjct: 30 LQDLGWYHGNLTRHAAEALLLSNGCDGSYLLRDSNETTGLYSLSVRAKDSVKH 82
>UniRef50_UPI0000E49CFC Cluster: PREDICTED: similar to Ras
GTPase-activating protein 1 (GTPase-activating protein)
(GAP) (Ras p21 protein activator) (p120GAP) (RasGAP);
n=3; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to Ras GTPase-activating protein 1
(GTPase-activating protein) (GAP) (Ras p21 protein
activator) (p120GAP) (RasGAP) - Strongylocentrotus
purpuratus
Length = 628
Score = 46.4 bits (105), Expect = 7e-04
Identities = 24/79 (30%), Positives = 45/79 (56%), Gaps = 9/79 (11%)
Frame = +2
Query: 296 WYRAELDGKEGLIPSNYIQM--------KNHSWYYGRITRADA-EKLLANKPEGGFLIRI 448
W ++ G+ G+I + ++ + W++G +++ +A E L + GGFLIR
Sbjct: 205 WVTSQRSGESGIIVQDLVKPVEGEIDPNEGKVWFHGNVSKEEAAETLWKDGDIGGFLIRN 264
Query: 449 SESSPGDFSLSVKCPDGVQ 505
S+ +PGD+SLS + P+ +Q
Sbjct: 265 SDKNPGDYSLSFRGPNTIQ 283
Score = 45.2 bits (102), Expect = 0.002
Identities = 26/81 (32%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = +2
Query: 272 LNMEDDMNWYRAELDGKEGLIPSNYIQMKNHSWYYGRITRADAEKLL--ANKPEGGFLIR 445
L + DD + + + + E + +N + WY+G + R AE L A+KP G +L+R
Sbjct: 36 LPVHDDFDPFESYTELPEETVDANLTAPPENEWYHGCLDRQSAELRLNAADKP-GSYLVR 94
Query: 446 ISESSPGDFSLSVKCPDGVQH 508
SE PG + LS G+ H
Sbjct: 95 ESERKPGSYVLSYLGQRGINH 115
>UniRef50_UPI0000D8C686 Cluster: Breast cancer anti-estrogen
resistance protein 3 (SH2 domain- containing protein 3B)
(Novel SH2-containing protein 2).; n=1; Danio rerio|Rep:
Breast cancer anti-estrogen resistance protein 3 (SH2
domain- containing protein 3B) (Novel SH2-containing
protein 2). - Danio rerio
Length = 628
Score = 46.4 bits (105), Expect = 7e-04
Identities = 23/53 (43%), Positives = 34/53 (64%)
Frame = +2
Query: 356 KNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
++H+WY+G I R AE L+ +G FLIR S SSPG++ L+ + + QH K
Sbjct: 42 RSHAWYHGAIPRQVAENLVQR--DGDFLIRDSLSSPGNYVLTCQWKNSPQHFK 92
>UniRef50_UPI0000ECD739 Cluster: Cytoplasmic tyrosine-protein kinase
BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in
chromosome X protein) (Epithelial and endothelial
tyrosine kinase) (ETK) (NTK38).; n=2; Gallus gallus|Rep:
Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2)
(Bone marrow tyrosine kinase gene in chromosome X
protein) (Epithelial and endothelial tyrosine kinase)
(ETK) (NTK38). - Gallus gallus
Length = 633
Score = 46.4 bits (105), Expect = 7e-04
Identities = 24/65 (36%), Positives = 39/65 (60%), Gaps = 5/65 (7%)
Frame = +2
Query: 281 EDDMNWYRA-ELDGKEGLIPSNYI--QMKNHS-WYYGRITRADAEKLLANKPE-GGFLIR 445
E+D W++ +L+G EG +PS + Q KN WY I+RA +E+LL P+ GF +
Sbjct: 217 EEDFAWWKVRDLEGNEGFVPSTCLAGQKKNQEIWYVAGISRAQSEQLLHQSPKISGFTVA 276
Query: 446 ISESS 460
+++ S
Sbjct: 277 LAQMS 281
>UniRef50_Q3ZB94 Cluster: Zgc:113360; n=3; Clupeocephala|Rep:
Zgc:113360 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 271
Score = 46.4 bits (105), Expect = 7e-04
Identities = 29/87 (33%), Positives = 45/87 (51%), Gaps = 4/87 (4%)
Frame = +2
Query: 266 KILNMEDDMNWY--RAELDGKEGLIPSNYIQMKNHSWYYGRITRADAEKLLA--NKPEGG 433
++ + +D W+ R+ G E IP N++ H W + ++R AE+LL+ G
Sbjct: 48 RLKGLSEDGCWWKVRSLQTGTENYIPCNHVSKVYHGWLFEGVSRQKAEELLSLPGNSAGS 107
Query: 434 FLIRISESSPGDFSLSVKCPDGVQHSK 514
FLIR S G +SLSV+ V+H K
Sbjct: 108 FLIRESPRERGLYSLSVR-HRSVKHYK 133
>UniRef50_Q9NH62 Cluster: Tyrosine kinase 5; n=2; Schistosoma
mansoni|Rep: Tyrosine kinase 5 - Schistosoma mansoni
(Blood fluke)
Length = 647
Score = 46.4 bits (105), Expect = 7e-04
Identities = 25/81 (30%), Positives = 45/81 (55%), Gaps = 8/81 (9%)
Frame = +2
Query: 269 ILNMEDDMNWYRAE--LDGKEGLIPSNYIQMKN----HSWYYGRITRADAEKLLA--NKP 424
+L + D W+ + G++G +PS+++ K W+ ++R D+E+LL
Sbjct: 140 LLLADTDSEWWLVQNLSSGRKGYVPSSFVAKKGSVEAEEWFMPMLSRKDSERLLLLEGNA 199
Query: 425 EGGFLIRISESSPGDFSLSVK 487
+G FL+R SE+S G +LSV+
Sbjct: 200 QGVFLVRESETSQGSLTLSVR 220
>UniRef50_Q9H3Y6 Cluster: Tyrosine-protein kinase Srms; n=17;
Amniota|Rep: Tyrosine-protein kinase Srms - Homo sapiens
(Human)
Length = 488
Score = 46.4 bits (105), Expect = 7e-04
Identities = 26/69 (37%), Positives = 39/69 (56%), Gaps = 8/69 (11%)
Frame = +2
Query: 326 GLIPSNYIQ------MKNHSWYYGRITRADAEKLLANKPE--GGFLIRISESSPGDFSLS 481
GL+P ++ + + WY+ ++R A++LL + P G FLIR SESS G +SLS
Sbjct: 100 GLVPITHVAKASPETLSDQPWYFSGVSRTQAQQLLLSPPNEPGAFLIRPSESSLGGYSLS 159
Query: 482 VKCPDGVQH 508
V+ V H
Sbjct: 160 VRAQAKVCH 168
>UniRef50_Q96JZ2 Cluster: Hematopoietic SH2 domain-containing
protein; n=72; Eumetazoa|Rep: Hematopoietic SH2
domain-containing protein - Homo sapiens (Human)
Length = 352
Score = 46.4 bits (105), Expect = 7e-04
Identities = 22/47 (46%), Positives = 30/47 (63%)
Frame = +2
Query: 368 WYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
W++G I+R DAE LL ++P G FLIR+S S G ++LS K H
Sbjct: 34 WFHGAISREDAENLLESQPLGSFLIRVSHSHVG-YTLSYKAQSSCCH 79
>UniRef50_UPI0000F2002E Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 457
Score = 46.0 bits (104), Expect = 9e-04
Identities = 19/54 (35%), Positives = 32/54 (59%)
Frame = +2
Query: 347 IQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
+ ++ SWY+G ++R +AE L E FL+R SES+ +S+++K G H
Sbjct: 351 LPLEKQSWYHGSVSRQEAEAQLQQCREASFLVRDSESATSKYSIALKTSQGCVH 404
>UniRef50_UPI0000E479E4 Cluster: PREDICTED: similar to Sh2d3c-prov
protein, partial; n=2; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to Sh2d3c-prov
protein, partial - Strongylocentrotus purpuratus
Length = 926
Score = 46.0 bits (104), Expect = 9e-04
Identities = 23/56 (41%), Positives = 38/56 (67%)
Frame = +2
Query: 320 KEGLIPSNYIQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVK 487
+E +PS +++H+W++G I+R AEKL+ + G FL+R S S PG+F L+V+
Sbjct: 112 EEFKLPSE--DVRSHAWFHGGISREKAEKLI--RENGDFLVRDSISKPGNFVLTVR 163
>UniRef50_UPI0000E460CB Cluster: PREDICTED: similar to V-crk sarcoma
virus CT10 oncogene homolog (avian)-like; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
V-crk sarcoma virus CT10 oncogene homolog (avian)-like -
Strongylocentrotus purpuratus
Length = 305
Score = 45.6 bits (103), Expect = 0.001
Identities = 21/49 (42%), Positives = 28/49 (57%)
Frame = +2
Query: 362 HSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
H W++G ITR++ + LL K G FL+R S + PGD L V V H
Sbjct: 16 HLWHFGGITRSETDNLLIQKRPGTFLVRDSRTCPGDSVLCVSENSKVSH 64
>UniRef50_UPI000051A29D Cluster: PREDICTED: similar to SHC-adaptor
protein CG3715-PA; n=2; Apocrita|Rep: PREDICTED: similar
to SHC-adaptor protein CG3715-PA - Apis mellifera
Length = 443
Score = 45.6 bits (103), Expect = 0.001
Identities = 23/66 (34%), Positives = 38/66 (57%), Gaps = 1/66 (1%)
Frame = +2
Query: 287 DMNWYRAELDGKEGLIP-SNYIQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSP 463
DM + + + L P S Q+K W++G ++RA+AE +L +G FL+R S+ SP
Sbjct: 318 DMQPFSSAISDMNKLSPHSQKQQLKQEIWFHGSVSRAEAESMLTR--DGDFLVRESQGSP 375
Query: 464 GDFSLS 481
G + L+
Sbjct: 376 GQYVLT 381
>UniRef50_Q56A36 Cluster: Hematopoietic SH2 domain-containing
protein homolog; n=3; Danio rerio|Rep: Hematopoietic SH2
domain-containing protein homolog - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 365
Score = 45.6 bits (103), Expect = 0.001
Identities = 22/47 (46%), Positives = 32/47 (68%)
Frame = +2
Query: 368 WYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
W++G I+R AE++L KP G FLIR+SES G ++LS + D +H
Sbjct: 34 WFHGIISRKAAEEMLMCKPAGYFLIRVSESRVG-YTLSYRAEDRCRH 79
>UniRef50_UPI00015B62FA Cluster: PREDICTED: similar to ras gtpase
activating protein; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ras gtpase activating protein -
Nasonia vitripennis
Length = 879
Score = 45.2 bits (102), Expect = 0.002
Identities = 27/87 (31%), Positives = 44/87 (50%), Gaps = 9/87 (10%)
Frame = +2
Query: 245 F*KNQVLKILN-MEDDMNWYRAELDGKEGLIPSNYIQMKNHS--------WYYGRITRAD 397
F K + + N M D W A G++GLI + + S W++ +T+++
Sbjct: 196 FQKGDIFFVHNDMGDGWLWVTAHRTGEQGLIFRELVDDLDDSIDPNTVFSWFHPNVTKSE 255
Query: 398 AEKLLANKPEGGFLIRISESSPGDFSL 478
A +L G FL+R S++SPGD+SL
Sbjct: 256 AVDMLVKAGPGSFLVRPSDNSPGDYSL 282
Score = 39.1 bits (87), Expect = 0.099
Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 1/50 (2%)
Frame = +2
Query: 362 HSWYYGRITRADAEKLLANKPE-GGFLIRISESSPGDFSLSVKCPDGVQH 508
+ WY+GR+ R AE+ L + G +L+R S+ PG + LS G+ H
Sbjct: 75 NQWYHGRLDRFTAEERLRDASRLGSYLVRESDRKPGSYVLSYLGRTGINH 124
>UniRef50_UPI0000E4816C Cluster: PREDICTED: similar to
phosphoinositide-3-kinase; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to
phosphoinositide-3-kinase - Strongylocentrotus
purpuratus
Length = 820
Score = 45.2 bits (102), Expect = 0.002
Identities = 16/48 (33%), Positives = 32/48 (66%)
Frame = +2
Query: 353 MKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPD 496
+ + WY+G I+R + + L + P+G FL+R S+ PG+++L+++ D
Sbjct: 497 LNDAEWYWGSISREEVNEKLKDMPDGTFLVRDSKQEPGNYTLTLRLDD 544
>UniRef50_UPI0000E47C6E Cluster: PREDICTED: similar to Grb2 adaptor
protein; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to Grb2 adaptor protein -
Strongylocentrotus purpuratus
Length = 532
Score = 44.8 bits (101), Expect = 0.002
Identities = 21/49 (42%), Positives = 33/49 (67%), Gaps = 1/49 (2%)
Frame = +2
Query: 344 YIQMKNHSWYYGRITRADAEKLL-ANKPEGGFLIRISESSPGDFSLSVK 487
Y QM W++G+I+RA AE++L + G L+R SE+ PG ++LSV+
Sbjct: 198 YSQMLPPVWFFGKISRAKAEEILHLSTSHGDLLLRESEAHPGQYTLSVR 246
>UniRef50_Q1LX18 Cluster: Novel protein similar to vertebrate src
homology 2 domain containing transforming protein C3;
n=1; Danio rerio|Rep: Novel protein similar to
vertebrate src homology 2 domain containing transforming
protein C3 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 501
Score = 44.8 bits (101), Expect = 0.002
Identities = 19/44 (43%), Positives = 30/44 (68%)
Frame = +2
Query: 350 QMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLS 481
Q++ WY+GR++R DAE LL +G FL+R S ++PG + L+
Sbjct: 400 QLRREMWYHGRMSRRDAENLLGR--DGDFLVRDSATNPGQYVLT 441
>UniRef50_Q9BI25 Cluster: SHK1 protein; n=2; Dictyostelium
discoideum|Rep: SHK1 protein - Dictyostelium discoideum
(Slime mold)
Length = 527
Score = 44.8 bits (101), Expect = 0.002
Identities = 20/56 (35%), Positives = 34/56 (60%), Gaps = 1/56 (1%)
Frame = +2
Query: 350 QMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLS-VKCPDGVQHSK 514
Q+ +W++G I+ +++E L KPEG FL+R S S G +++S V G+ H +
Sbjct: 418 QLMECAWFHGDISTSESENRLRQKPEGTFLVRFSTSEYGAYTISKVSKNGGISHQR 473
>UniRef50_Q7QG48 Cluster: ENSANGP00000010943; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000010943 - Anopheles gambiae
str. PEST
Length = 256
Score = 44.8 bits (101), Expect = 0.002
Identities = 23/49 (46%), Positives = 30/49 (61%), Gaps = 1/49 (2%)
Frame = +2
Query: 365 SWYYGRITRADAEKLLANKPEGG-FLIRISESSPGDFSLSVKCPDGVQH 508
SWY+G ++R DA LL N+ E G FL+R S + GDF L V+ V H
Sbjct: 11 SWYFGAMSRQDATDLLLNERESGVFLVRDSTTIVGDFVLCVREDSKVSH 59
>UniRef50_Q17PR7 Cluster: Putative uncharacterized protein; n=1;
Aedes aegypti|Rep: Putative uncharacterized protein -
Aedes aegypti (Yellowfever mosquito)
Length = 312
Score = 44.8 bits (101), Expect = 0.002
Identities = 19/58 (32%), Positives = 35/58 (60%)
Frame = +2
Query: 314 DGKEGLIPSNYIQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVK 487
D E ++ + + + WY+G++TR+ A+K LA + G FL+R SE+ F++S +
Sbjct: 144 DNLETMMNNVRTDLLRYGWYWGKLTRSAAQKRLARQDNGTFLVRDSETEKHQFAISFR 201
>UniRef50_Q16XX9 Cluster: Tyrosine-protein kinase shark; n=2;
Culicidae|Rep: Tyrosine-protein kinase shark - Aedes
aegypti (Yellowfever mosquito)
Length = 939
Score = 44.8 bits (101), Expect = 0.002
Identities = 23/52 (44%), Positives = 33/52 (63%), Gaps = 1/52 (1%)
Frame = +2
Query: 356 KNHSWYYGRITRADAEKLLANKPEGG-FLIRISESSPGDFSLSVKCPDGVQH 508
+N W++G+I+R AE++L + G F++R S SS GDF LSV D V H
Sbjct: 5 ENLCWFHGKISRERAEEILRQEGGNGVFMVRESTSSEGDFVLSVLFQDEVVH 56
>UniRef50_Q08881 Cluster: Tyrosine-protein kinase ITK/TSK; n=18;
Euteleostomi|Rep: Tyrosine-protein kinase ITK/TSK - Homo
sapiens (Human)
Length = 620
Score = 44.8 bits (101), Expect = 0.002
Identities = 25/74 (33%), Positives = 46/74 (62%), Gaps = 8/74 (10%)
Frame = +2
Query: 287 DMNWYRAE-LDGKEGLIPSNYI------QMKNHSWYYGRITRADAEKLLANK-PEGGFLI 442
+++W+R + +G EG +PS+Y+ ++ + WY I+R AEKLL + EG F++
Sbjct: 205 EIHWWRVQDRNGHEGYVPSSYLVEKSPNNLETYEWYNKSISRDKAEKLLLDTGKEGAFMV 264
Query: 443 RISESSPGDFSLSV 484
R S ++ G +++SV
Sbjct: 265 RDSRTA-GTYTVSV 277
>UniRef50_UPI0000F207BA Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 524
Score = 44.4 bits (100), Expect = 0.003
Identities = 23/47 (48%), Positives = 31/47 (65%)
Frame = +2
Query: 368 WYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
W +G TR +AE+LL +KP G FL+R+SES G F LS + D +H
Sbjct: 128 WLHGFATRREAEQLLQDKPLGCFLLRLSESKIG-FVLSYRGEDRCRH 173
>UniRef50_UPI0000D57904 Cluster: PREDICTED: similar to CG9098-PA,
isoform A, partial; n=1; Tribolium castaneum|Rep:
PREDICTED: similar to CG9098-PA, isoform A, partial -
Tribolium castaneum
Length = 851
Score = 44.4 bits (100), Expect = 0.003
Identities = 18/45 (40%), Positives = 32/45 (71%)
Frame = +2
Query: 353 MKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVK 487
+++H+WY+G I R+ AE ++ + EGGFL+R S PG++ L+ +
Sbjct: 171 LRSHAWYHGAIPRSRAEDIV--REEGGFLVRDCTSQPGNYVLTCR 213
>UniRef50_A7SCW1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 275
Score = 44.4 bits (100), Expect = 0.003
Identities = 20/47 (42%), Positives = 28/47 (59%)
Frame = +2
Query: 368 WYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
WY+G + R + E +L KP G +L+R S + PGD+ LSV V H
Sbjct: 9 WYHGVLKRVETEGILNGKPPGVWLVRDSTTIPGDYVLSVSESGKVSH 55
Score = 35.9 bits (79), Expect = 0.93
Identities = 15/42 (35%), Positives = 30/42 (71%), Gaps = 1/42 (2%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRA-ELDGKEGLIPSNYIQMKNHS 367
F K +L +++ E+D NW++A + G+EG+IP Y+Q+ +++
Sbjct: 121 FKKGDILTVISKEED-NWWKARDSAGREGMIPKPYVQVLSNA 161
>UniRef50_Q9NSE2 Cluster: Cytokine-inducible SH2-containing protein;
n=26; Tetrapoda|Rep: Cytokine-inducible SH2-containing
protein - Homo sapiens (Human)
Length = 258
Score = 44.4 bits (100), Expect = 0.003
Identities = 25/65 (38%), Positives = 35/65 (53%), Gaps = 2/65 (3%)
Frame = +2
Query: 311 LDGKEGL--IPSNYIQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSV 484
LD +E L I + ++ WY+G IT ++A + L PEG FL+R S F+LSV
Sbjct: 61 LDPEEDLLCIAKTFSYLRESGWYWGSITASEARQHLQKMPEGTFLVRDSTHPSYLFTLSV 120
Query: 485 KCPDG 499
K G
Sbjct: 121 KTTRG 125
>UniRef50_UPI0000D5590C Cluster: PREDICTED: similar to Suppressor of
cytokine signaling 6 (SOCS-6) (Suppressor of cytokine
signaling 4) (SOCS-4) (Cytokine-inducible SH2 protein 4)
(CIS-4); n=1; Tribolium castaneum|Rep: PREDICTED:
similar to Suppressor of cytokine signaling 6 (SOCS-6)
(Suppressor of cytokine signaling 4) (SOCS-4)
(Cytokine-inducible SH2 protein 4) (CIS-4) - Tribolium
castaneum
Length = 297
Score = 43.6 bits (98), Expect = 0.005
Identities = 23/62 (37%), Positives = 37/62 (59%), Gaps = 1/62 (1%)
Frame = +2
Query: 332 IPSN-YIQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
IP++ I + N WY+G + A+AE+ L KP+G FL+R S S+ FS+S + H
Sbjct: 134 IPTDEIISLSNCYWYWGPMPTAEAEEKLQFKPDGTFLVRDSGSTNYLFSISFRSVGKTMH 193
Query: 509 SK 514
++
Sbjct: 194 AR 195
>UniRef50_UPI0000D555ED Cluster: PREDICTED: similar to CG32406-PA;
n=2; Endopterygota|Rep: PREDICTED: similar to CG32406-PA
- Tribolium castaneum
Length = 562
Score = 43.6 bits (98), Expect = 0.005
Identities = 19/52 (36%), Positives = 31/52 (59%)
Frame = +2
Query: 350 QMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQ 505
+++ W+ I R A ++LA +P G F++R S S PG F+LS++ P Q
Sbjct: 423 ELRTAPWFQAGIPREIALEILAQEPVGAFMVRESTSKPGCFALSLRVPRSFQ 474
>UniRef50_Q4RUJ0 Cluster: Chromosome 1 SCAF14995, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 1 SCAF14995, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 123
Score = 43.6 bits (98), Expect = 0.005
Identities = 18/49 (36%), Positives = 32/49 (65%)
Frame = +2
Query: 368 WYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
WY+G ++R++AE LL E +L+R S+++ ++SLS++ G H K
Sbjct: 52 WYHGSLSRSEAECLLTLCKECSYLVRTSQTNHSEYSLSLRSCQGFMHMK 100
>UniRef50_Q08BY6 Cluster: Zgc:153964; n=3; Danio rerio|Rep:
Zgc:153964 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 511
Score = 43.6 bits (98), Expect = 0.005
Identities = 22/72 (30%), Positives = 39/72 (54%), Gaps = 5/72 (6%)
Frame = +2
Query: 326 GLIPSNYI---QMKNHSWYYGRITRADAEKLLANKPE--GGFLIRISESSPGDFSLSVKC 490
G +P NY+ +++ W++G++ R A L + G FL+R+SES + LSV+
Sbjct: 117 GFVPYNYLARDSVESQPWFFGKMNRVGAVSHLMSDENNYGSFLVRVSESDDMGYVLSVRT 176
Query: 491 PDGVQHSKY*ET 526
+ +H K +T
Sbjct: 177 KENAKHFKIFQT 188
>UniRef50_A7RR81 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 473
Score = 43.6 bits (98), Expect = 0.005
Identities = 21/43 (48%), Positives = 29/43 (67%)
Frame = +2
Query: 353 MKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLS 481
M+ WY+G I+R +AE LL + EG FL+R S+S PG + LS
Sbjct: 374 MRAKDWYHGPISRGEAELLLED--EGDFLVRESKSQPGQYVLS 414
>UniRef50_UPI0000F1F923 Cluster: PREDICTED: similar to SH2 domain
containing 4B; n=2; Danio rerio|Rep: PREDICTED: similar
to SH2 domain containing 4B - Danio rerio
Length = 266
Score = 43.2 bits (97), Expect = 0.006
Identities = 20/47 (42%), Positives = 30/47 (63%)
Frame = +2
Query: 368 WYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
W++G I+R D+E LL N G FL+R+SE G ++LS + G +H
Sbjct: 160 WFHGIISREDSETLLMNAAVGSFLVRVSERIWG-YTLSYRTASGFKH 205
>UniRef50_UPI0000E48882 Cluster: PREDICTED: similar to tensin
homologue; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to tensin homologue -
Strongylocentrotus purpuratus
Length = 387
Score = 43.2 bits (97), Expect = 0.006
Identities = 19/40 (47%), Positives = 26/40 (65%)
Frame = +2
Query: 368 WYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVK 487
WY ITR DA +L ++P G F++R S S PG F L++K
Sbjct: 175 WYKPSITRDDAINILKDRPPGTFIVRDSNSFPGAFGLALK 214
>UniRef50_UPI0000567587 Cluster: PREDICTED: hypothetical protein;
n=2; Euteleostomi|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 519
Score = 43.2 bits (97), Expect = 0.006
Identities = 20/55 (36%), Positives = 30/55 (54%)
Frame = +2
Query: 350 QMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
++ WY+G ITR +AE+ L N P+G FL+R S SLS + H++
Sbjct: 362 KLAKQGWYWGPITRWEAEEKLVNLPDGSFLVRDSSDDRYLLSLSFRSQGKTLHTR 416
>UniRef50_Q9VRS2 Cluster: CG32406-PA; n=3; Sophophora|Rep:
CG32406-PA - Drosophila melanogaster (Fruit fly)
Length = 474
Score = 43.2 bits (97), Expect = 0.006
Identities = 18/49 (36%), Positives = 32/49 (65%)
Frame = +2
Query: 347 IQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCP 493
+++K+ WY I+R A ++L +K G FL+R S S PG ++L+++ P
Sbjct: 335 LELKDACWYQAGISRDIAVEVLQSKSPGAFLVRKSSSKPGCYALTLRVP 383
>UniRef50_Q9N597 Cluster: Phosphoinositide kinase adapter subunit
protein 1; n=2; Caenorhabditis|Rep: Phosphoinositide
kinase adapter subunit protein 1 - Caenorhabditis
elegans
Length = 522
Score = 43.2 bits (97), Expect = 0.006
Identities = 17/45 (37%), Positives = 30/45 (66%)
Frame = +2
Query: 353 MKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVK 487
+ WY+ R+ K L+++P+G F++R + S+PGD++LSVK
Sbjct: 15 LMEQGWYWADADRSAVSKALSDQPDGSFIVR-NASTPGDYTLSVK 58
>UniRef50_O14544 Cluster: Suppressor of cytokine signaling 6; n=27;
Euteleostomi|Rep: Suppressor of cytokine signaling 6 -
Homo sapiens (Human)
Length = 535
Score = 43.2 bits (97), Expect = 0.006
Identities = 21/55 (38%), Positives = 30/55 (54%)
Frame = +2
Query: 350 QMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
++ WY+G ITR +AE LAN P+G FL+R S SLS + H++
Sbjct: 378 KLAKQGWYWGPITRWEAEGKLANVPDGSFLVRDSSDDRYLLSLSFRSHGKTLHTR 432
>UniRef50_Q13239 Cluster: SRC-like-adapter; n=26; Euteleostomi|Rep:
SRC-like-adapter - Homo sapiens (Human)
Length = 276
Score = 43.2 bits (97), Expect = 0.006
Identities = 27/78 (34%), Positives = 42/78 (53%), Gaps = 4/78 (5%)
Frame = +2
Query: 266 KILNMEDDMNWYRA-ELD-GKEGLIPSNYIQMKNHSWYYGRITRADAEKLLA--NKPEGG 433
K+ + D+ W++A L G+E IP + H W + + R AE+LL + G
Sbjct: 48 KLRVISDEGGWWKAISLSTGRESYIPGICVARVYHGWLFEGLGRDKAEELLQLPDTKVGS 107
Query: 434 FLIRISESSPGDFSLSVK 487
F+IR SE+ G +SLSV+
Sbjct: 108 FMIRESETKKGFYSLSVR 125
>UniRef50_Q9NP31 Cluster: SH2 domain-containing protein 2A; n=23;
Theria|Rep: SH2 domain-containing protein 2A - Homo
sapiens (Human)
Length = 389
Score = 43.2 bits (97), Expect = 0.006
Identities = 17/32 (53%), Positives = 26/32 (81%)
Frame = +2
Query: 365 SWYYGRITRADAEKLLANKPEGGFLIRISESS 460
+W++G ITR +AE+LL KP+G +L+R SES+
Sbjct: 94 AWFHGFITRREAERLLEPKPQGCYLVRFSESA 125
>UniRef50_P42679 Cluster: Megakaryocyte-associated tyrosine-protein
kinase; n=38; Euteleostomi|Rep: Megakaryocyte-associated
tyrosine-protein kinase - Homo sapiens (Human)
Length = 507
Score = 43.2 bits (97), Expect = 0.006
Identities = 29/100 (29%), Positives = 49/100 (49%), Gaps = 12/100 (12%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAE--LDGKEGLIPSNYIQMKNH----------SWYYGRIT 388
F K V+ IL ++ +WYR + G+EGL+ + ++ + W++G+I+
Sbjct: 69 FRKGDVVTILEACENKSWYRVKHHTSGQEGLLAAGALREREALSADPKLSLMPWFHGKIS 128
Query: 389 RADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
+A + L +G FL+R S PGD+ L V V H
Sbjct: 129 GQEAVQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVIH 168
>UniRef50_Q9NZM3 Cluster: Intersectin-2; n=40; Euteleostomi|Rep:
Intersectin-2 - Homo sapiens (Human)
Length = 1696
Score = 43.2 bits (97), Expect = 0.006
Identities = 17/41 (41%), Positives = 29/41 (70%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYIQMKNHS 367
F K Q++ ++N +DD +W++ E++G GL PSNY++M S
Sbjct: 1147 FSKGQLINVMN-KDDPDWWQGEINGVTGLFPSNYVKMTTDS 1186
>UniRef50_P08630 Cluster: Tyrosine-protein kinase Btk29A; n=10;
Endopterygota|Rep: Tyrosine-protein kinase Btk29A -
Drosophila melanogaster (Fruit fly)
Length = 786
Score = 43.2 bits (97), Expect = 0.006
Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 7/96 (7%)
Frame = +2
Query: 251 KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYIQMK------NHSWYYGRITRADAEKLL 412
KN ++++ + W + G G IPSNY++ K + WY G ++R AE LL
Sbjct: 365 KNAEYEVIDDSQEHWWKVKDALGNVGYIPSNYVKPKALLGLERYEWYVGDMSRQRAESLL 424
Query: 413 -ANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSKY 517
EG F++R S S+ G ++LS+ H K+
Sbjct: 425 KQGDKEGCFVVRKS-STKGLYTLSLHTKVPQSHVKH 459
>UniRef50_UPI00015A6A53 Cluster: hypothetical protein LOC406311;
n=1; Danio rerio|Rep: hypothetical protein LOC406311 -
Danio rerio
Length = 394
Score = 42.7 bits (96), Expect = 0.008
Identities = 23/60 (38%), Positives = 32/60 (53%)
Frame = +2
Query: 353 MKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSKY*ETPR 532
++ SW+ G + R AE+LL KP G FLIR + SS ++ SV V+H T R
Sbjct: 287 LREESWFVGDLARGPAEELLLGKPNGAFLIR-NSSSKDCYACSVVVNSQVRHCVIRHTER 345
Score = 34.7 bits (76), Expect = 2.1
Identities = 14/46 (30%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
Frame = +2
Query: 353 MKNHSWYYGRITRADAEKLLANKPEGGFLIR-ISESSPGDFSLSVK 487
+++ WY+ I+R + ++L P+G FL+R S G+++L+V+
Sbjct: 1 LQDAEWYWADISREEVNEILHGMPDGAFLVRDASCKVQGEYTLTVR 46
>UniRef50_Q6PBV3 Cluster: Zgc:73230; n=2; Danio rerio|Rep: Zgc:73230
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 321
Score = 42.7 bits (96), Expect = 0.008
Identities = 23/60 (38%), Positives = 32/60 (53%)
Frame = +2
Query: 353 MKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSKY*ETPR 532
++ SW+ G + R AE+LL KP G FLIR + SS ++ SV V+H T R
Sbjct: 214 LREESWFVGDLARGPAEELLLGKPNGAFLIR-NSSSKDCYACSVVVNSQVRHCVIRHTER 272
Score = 35.5 bits (78), Expect = 1.2
Identities = 17/52 (32%), Positives = 32/52 (61%), Gaps = 1/52 (1%)
Frame = +2
Query: 335 PSNYIQMKNHSWYYGRITRADAEKLLANKPEGGFLIR-ISESSPGDFSLSVK 487
PS+ +Q + WY+ I+R + ++L P+G FL+R S G+++L+V+
Sbjct: 23 PSDLLQ--DAEWYWADISREEVNEILHGMPDGAFLVRDASCKVQGEYTLTVR 72
>UniRef50_Q8WP81 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 533
Score = 42.7 bits (96), Expect = 0.008
Identities = 26/71 (36%), Positives = 39/71 (54%), Gaps = 1/71 (1%)
Frame = +2
Query: 290 MNWY-RAELDGKEGLIPSNYIQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPG 466
++W+ R EL GL P W++G I+R +E LL +KP G FL+R+SE G
Sbjct: 371 IDWFQREELPRGTGLDPKTRAPAP---WFHGIISRDQSEVLLTHKPTGSFLVRVSERIWG 427
Query: 467 DFSLSVKCPDG 499
+++S DG
Sbjct: 428 -YTVSYASRDG 437
>UniRef50_Q7Q6Z7 Cluster: ENSANGP00000017664; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000017664 - Anopheles gambiae
str. PEST
Length = 397
Score = 42.7 bits (96), Expect = 0.008
Identities = 16/51 (31%), Positives = 35/51 (68%)
Frame = +2
Query: 335 PSNYIQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVK 487
P+ ++++ WY+G+I+R A++ + + P+G FL+R + + G+F+L +K
Sbjct: 131 PNTPQELRDAEWYWGKISRDVAKEKMMDAPDGSFLVRDAINDAGEFTLVLK 181
>UniRef50_O44235 Cluster: HrSH2 protein; n=1; Halocynthia
roretzi|Rep: HrSH2 protein - Halocynthia roretzi (Sea
squirt)
Length = 867
Score = 42.7 bits (96), Expect = 0.008
Identities = 25/88 (28%), Positives = 50/88 (56%)
Frame = +2
Query: 251 KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYIQMKNHSWYYGRITRADAEKLLANKPEG 430
+N++ + ++ + R EL+ + + S+ +++++W++GR+ R AE L+ + EG
Sbjct: 15 QNKIPEEVDAAPSQDVLRKELENE---LRSDKSDIRSYAWFHGRMPRDIAEDLI--RREG 69
Query: 431 GFLIRISESSPGDFSLSVKCPDGVQHSK 514
FLIR S ++ G+F L+ K H K
Sbjct: 70 DFLIRESVNNAGEFVLTCKYKSATYHFK 97
>UniRef50_Q24145 Cluster: Tyrosine-protein kinase shark; n=2;
Sophophora|Rep: Tyrosine-protein kinase shark -
Drosophila melanogaster (Fruit fly)
Length = 939
Score = 42.7 bits (96), Expect = 0.008
Identities = 21/48 (43%), Positives = 30/48 (62%), Gaps = 1/48 (2%)
Frame = +2
Query: 368 WYYGRITRADAEKLLANKPEGG-FLIRISESSPGDFSLSVKCPDGVQH 508
WY+G ++R A++LL E G FL+R S ++ GDF LS+ C V H
Sbjct: 10 WYHGNLSREAADELLKQGYEDGTFLVRESSTAAGDFVLSLLCQGEVCH 57
>UniRef50_Q15811 Cluster: Intersectin-1; n=93; Eumetazoa|Rep:
Intersectin-1 - Homo sapiens (Human)
Length = 1721
Score = 42.7 bits (96), Expect = 0.008
Identities = 16/37 (43%), Positives = 28/37 (75%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYIQM 355
F K Q++ +LN ED +W++ E++G+ GL PSNY+++
Sbjct: 1176 FNKGQIINVLNKEDP-DWWKGEVNGQVGLFPSNYVKL 1211
>UniRef50_Q9Y1X9 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 573
Score = 42.3 bits (95), Expect = 0.011
Identities = 20/41 (48%), Positives = 30/41 (73%), Gaps = 2/41 (4%)
Frame = +2
Query: 368 WYYGRITRADAEKLLAN--KPEGGFLIRISESSPGDFSLSV 484
WY+GRI+R DAE+LL N + G FL+R S ++ G++ LS+
Sbjct: 9 WYHGRISRLDAEQLLDNFGRLSGSFLVRDSLTTTGEYVLSL 49
>UniRef50_Q9TYT3 Cluster: Putative uncharacterized protein; n=5;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 316
Score = 42.3 bits (95), Expect = 0.011
Identities = 19/38 (50%), Positives = 27/38 (71%)
Frame = +2
Query: 368 WYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLS 481
WY+G ++R DA+ LL K EG FL+R S+ +PG + LS
Sbjct: 211 WYHGNLSREDAQALL--KTEGDFLVRQSDHTPGKYVLS 246
>UniRef50_Q8INY1 Cluster: CG15154-PB, isoform B; n=6; Coelomata|Rep:
CG15154-PB, isoform B - Drosophila melanogaster (Fruit
fly)
Length = 720
Score = 42.3 bits (95), Expect = 0.011
Identities = 23/60 (38%), Positives = 39/60 (65%)
Frame = +2
Query: 305 AELDGKEGLIPSNYIQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSV 484
+++D L+P + ++ N S+Y+G++ R +AE LL KPEG FL+R +S+ +F SV
Sbjct: 454 SQIDFMHCLVP-DLEKITNSSFYWGKMDRYEAEHLLEGKPEGTFLLR--DSAQEEFLFSV 510
>UniRef50_A7SGW3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 169
Score = 42.3 bits (95), Expect = 0.011
Identities = 20/61 (32%), Positives = 35/61 (57%)
Frame = +2
Query: 332 IPSNYIQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHS 511
+ S+ + N WY+G ++ +AEK L N+P+G FL+R SE+ S+S + H+
Sbjct: 17 LSSSLKTLSNCGWYWGPMSSKEAEKELYNQPDGCFLVRDSENDYHLLSVSFRSKGATCHT 76
Query: 512 K 514
+
Sbjct: 77 R 77
>UniRef50_P16591 Cluster: Proto-oncogene tyrosine-protein kinase
FER; n=109; root|Rep: Proto-oncogene tyrosine-protein
kinase FER - Homo sapiens (Human)
Length = 822
Score = 42.3 bits (95), Expect = 0.011
Identities = 19/44 (43%), Positives = 28/44 (63%)
Frame = +2
Query: 353 MKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSV 484
+ WY+G I R +A++LL K +G FL+R S PG++ LSV
Sbjct: 455 LAEQDWYHGAIPRIEAQELL--KKQGDFLVRESHGKPGEYVLSV 496
>UniRef50_Q9XYM0 Cluster: Adapter molecule Crk; n=7;
Endopterygota|Rep: Adapter molecule Crk - Drosophila
melanogaster (Fruit fly)
Length = 271
Score = 42.3 bits (95), Expect = 0.011
Identities = 20/43 (46%), Positives = 30/43 (69%), Gaps = 1/43 (2%)
Frame = +2
Query: 362 HSWYYGRITRADAEKLLANKPEGG-FLIRISESSPGDFSLSVK 487
+SWY+G ++R DA ++L N+ E G FL+R S S GD+ L V+
Sbjct: 10 NSWYFGPMSRQDATEVLMNERERGVFLVRDSNSIAGDYVLCVR 52
>UniRef50_UPI00015B6133 Cluster: PREDICTED: similar to protein
tyrosine kinase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to protein tyrosine kinase - Nasonia
vitripennis
Length = 739
Score = 41.9 bits (94), Expect = 0.014
Identities = 22/49 (44%), Positives = 29/49 (59%), Gaps = 2/49 (4%)
Frame = +2
Query: 368 WYYGRITRADAEKLLAN--KPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
W++G ++R DAE LL + G FL+R S SS GD+ LSV V H
Sbjct: 9 WFHGNLSREDAESLLLEDGRDNGTFLVRESSSSLGDYVLSVLHDGEVAH 57
>UniRef50_UPI00015B5EF2 Cluster: PREDICTED: similar to
ENSANGP00000021630; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000021630 - Nasonia
vitripennis
Length = 389
Score = 41.9 bits (94), Expect = 0.014
Identities = 18/54 (33%), Positives = 32/54 (59%)
Frame = +2
Query: 350 QMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHS 511
+++ W+ I R ++L+ +PEG F++R S S PG ++LS++ P Q S
Sbjct: 250 ELRRAPWFQAGIPREITLEVLSQEPEGAFMVRESTSKPGCYALSLRVPREFQPS 303
>UniRef50_Q4RUN4 Cluster: Chromosome 12 SCAF14993, whole genome
shotgun sequence; n=2; Tetraodon nigroviridis|Rep:
Chromosome 12 SCAF14993, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1136
Score = 41.5 bits (93), Expect = 0.019
Identities = 20/50 (40%), Positives = 31/50 (62%), Gaps = 1/50 (2%)
Frame = +2
Query: 368 WYYGRITRADAEKLLANKPEG-GFLIRISESSPGDFSLSVKCPDGVQHSK 514
WY+G IT+ +A LL + FL+R S+++PGD+SL + D +Q K
Sbjct: 359 WYHGHITKKEAYNLLMTVGQVCSFLVRPSDNTPGDYSLFFRTNDIIQRFK 408
Score = 39.9 bits (89), Expect = 0.057
Identities = 20/50 (40%), Positives = 29/50 (58%), Gaps = 1/50 (2%)
Frame = +2
Query: 335 PSNYIQMKNHSWYYGRITRADAEKLLAN-KPEGGFLIRISESSPGDFSLS 481
PSN+ + WY+G++ R AE+ L + G +LIR S+ PG F LS
Sbjct: 174 PSNHSPPRMPRWYHGKLDRTIAEERLRQARNPGSYLIRESDRRPGSFVLS 223
>UniRef50_Q9VMJ4 Cluster: CG9098-PA, isoform A; n=5; Diptera|Rep:
CG9098-PA, isoform A - Drosophila melanogaster (Fruit
fly)
Length = 944
Score = 41.5 bits (93), Expect = 0.019
Identities = 18/53 (33%), Positives = 33/53 (62%)
Frame = +2
Query: 350 QMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
++++H+WY+G + R AE+++ + EG FL+R S P ++ LS + V H
Sbjct: 234 ELRSHAWYHGALPRQRAEEIV--QREGDFLVRDCASQPDNYVLSCRSKAAVLH 284
>UniRef50_Q554D0 Cluster: Signal transducer and activator of
transcription (STAT) family protein; n=2; Dictyostelium
discoideum|Rep: Signal transducer and activator of
transcription (STAT) family protein - Dictyostelium
discoideum AX4
Length = 811
Score = 41.5 bits (93), Expect = 0.019
Identities = 21/54 (38%), Positives = 29/54 (53%), Gaps = 4/54 (7%)
Frame = +2
Query: 368 WY----YGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSKY 517
WY YG IT+++ L PEG FLIR S+S PG F+++ D K+
Sbjct: 692 WYSGLIYGLITKSECNSYLTTLPEGSFLIRFSDSVPGAFAVAYVTNDESDRVKH 745
>UniRef50_Q380D8 Cluster: ENSANGP00000027059; n=2; Culicidae|Rep:
ENSANGP00000027059 - Anopheles gambiae str. PEST
Length = 339
Score = 41.5 bits (93), Expect = 0.019
Identities = 18/52 (34%), Positives = 33/52 (63%)
Frame = +2
Query: 344 YIQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDG 499
Y ++ + WY+ + R+ + +LLA+K G FL+R S + P ++LS++ P G
Sbjct: 209 YRRLLDECWYHENLPRSLSLQLLADKLPGSFLVRKSTTQPDCYALSLRVPPG 260
>UniRef50_Q29LD7 Cluster: GA13535-PA; n=1; Drosophila
pseudoobscura|Rep: GA13535-PA - Drosophila pseudoobscura
(Fruit fly)
Length = 613
Score = 41.5 bits (93), Expect = 0.019
Identities = 23/60 (38%), Positives = 39/60 (65%)
Frame = +2
Query: 305 AELDGKEGLIPSNYIQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSV 484
+++D L+P + ++ N S+Y+G++ R +AE LL KPEG FL+R +S+ +F SV
Sbjct: 434 SQIDFMHCLVP-DLERIINSSFYWGKMDRYEAEHLLEGKPEGTFLLR--DSAQEEFLFSV 490
>UniRef50_P98077 Cluster: SHC-transforming protein 2; n=15;
Tetrapoda|Rep: SHC-transforming protein 2 - Homo sapiens
(Human)
Length = 551
Score = 41.5 bits (93), Expect = 0.019
Identities = 17/44 (38%), Positives = 31/44 (70%)
Frame = +2
Query: 350 QMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLS 481
Q++ WY+GR++R AE++L + +G FL+R S ++PG + L+
Sbjct: 450 QLRQEPWYHGRMSRRAAERML--RADGDFLVRDSVTNPGQYVLT 491
>UniRef50_P20936 Cluster: Ras GTPase-activating protein 1; n=50;
Euteleostomi|Rep: Ras GTPase-activating protein 1 - Homo
sapiens (Human)
Length = 1047
Score = 41.5 bits (93), Expect = 0.019
Identities = 19/55 (34%), Positives = 34/55 (61%), Gaps = 1/55 (1%)
Frame = +2
Query: 368 WYYGRITRADAEKLLANKPEG-GFLIRISESSPGDFSLSVKCPDGVQHSKY*ETP 529
W++G+I++ +A LL + FL+R S+++PGD+SL + + +Q K TP
Sbjct: 351 WFHGKISKQEAYNLLMTVGQVCSFLVRPSDNTPGDYSLYFRTNENIQRFKICPTP 405
Score = 35.5 bits (78), Expect = 1.2
Identities = 17/41 (41%), Positives = 25/41 (60%), Gaps = 1/41 (2%)
Frame = +2
Query: 362 HSWYYGRITRADAEKLLANKPEGG-FLIRISESSPGDFSLS 481
+ WY+G++ R AE+ L + G +LIR S+ PG F LS
Sbjct: 179 NQWYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLS 219
>UniRef50_Q6VYH9 Cluster: Hematopoietic SH2 domain-containing
protein; n=2; Murinae|Rep: Hematopoietic SH2
domain-containing protein - Mus musculus (Mouse)
Length = 334
Score = 41.5 bits (93), Expect = 0.019
Identities = 20/47 (42%), Positives = 30/47 (63%)
Frame = +2
Query: 368 WYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
W++G I+R AE +L ++P G FLIR+S S G ++LS K +H
Sbjct: 34 WFHGTISREAAENMLESQPLGTFLIRVSHSHVG-YTLSYKAQTCCRH 79
>UniRef50_UPI0000DB7263 Cluster: PREDICTED: similar to Suppressor of
cytokine signaling 6 (SOCS-6) (Suppressor of cytokine
signaling 4) (SOCS-4) (Cytokine-inducible SH2 protein 4)
(CIS-4); n=1; Apis mellifera|Rep: PREDICTED: similar to
Suppressor of cytokine signaling 6 (SOCS-6) (Suppressor
of cytokine signaling 4) (SOCS-4) (Cytokine-inducible
SH2 protein 4) (CIS-4) - Apis mellifera
Length = 358
Score = 41.1 bits (92), Expect = 0.025
Identities = 17/56 (30%), Positives = 33/56 (58%)
Frame = +2
Query: 347 IQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
+++ N+ WY+G I+ +A+ L ++P+G FL+R S +LS K + H++
Sbjct: 200 LKLSNYGWYWGPISGNEADAKLLSEPDGAFLVRDSSDDRYVLTLSFKSSGKLLHAR 255
>UniRef50_Q86SD5 Cluster: Tensin homologue; n=1; Ciona
intestinalis|Rep: Tensin homologue - Ciona intestinalis
(Transparent sea squirt)
Length = 969
Score = 41.1 bits (92), Expect = 0.025
Identities = 18/51 (35%), Positives = 26/51 (50%)
Frame = +2
Query: 335 PSNYIQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVK 487
P +I+ WY I R A +L +P G F++R S PG F L++K
Sbjct: 673 PPKFIKDTTAYWYKPEINRDQAHAMLRTRPPGSFVVRASRCYPGAFGLALK 723
>UniRef50_Q8N5H7 Cluster: SH2 domain-containing protein 3C; n=33;
Amniota|Rep: SH2 domain-containing protein 3C - Homo
sapiens (Human)
Length = 860
Score = 41.1 bits (92), Expect = 0.025
Identities = 21/54 (38%), Positives = 34/54 (62%)
Frame = +2
Query: 353 MKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
+++H+WY+GRI R +E L+ + G FLIR S +S GD+ L+ + + H K
Sbjct: 215 LRSHAWYHGRIPREVSETLV--QRNGDFLIRDSLTSLGDYVLTCRWRNQALHFK 266
>UniRef50_UPI0000660CF8 Cluster: Crk-like protein.; n=3;
Euteleostomi|Rep: Crk-like protein. - Takifugu rubripes
Length = 314
Score = 40.7 bits (91), Expect = 0.033
Identities = 19/57 (33%), Positives = 30/57 (52%)
Frame = +2
Query: 338 SNYIQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
S + +WY+G ++R +A+ L + G FL+R S + GD+ LSV V H
Sbjct: 4 SRFDSADRSAWYFGPVSRHEAQNRLQGQKHGIFLVRDSSTCHGDYVLSVSENSKVSH 60
>UniRef50_UPI000065F386 Cluster: Homolog of Homo sapiens "Intersectin
2 (SH3 domain-containing protein 1B) (SH3P18)
(SH3P18-like WASP associated protein). SPLICE ISOFORM 2;
n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens
"Intersectin 2 (SH3 domain-containing protein 1B)
(SH3P18) (SH3P18-like WASP associated protein). SPLICE
ISOFORM 2 - Takifugu rubripes
Length = 1529
Score = 40.7 bits (91), Expect = 0.033
Identities = 22/75 (29%), Positives = 41/75 (54%), Gaps = 4/75 (5%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYIQMKNHSWYYGRITRADAEKL----L 412
F K Q++ +L+ ++D +W++ EL+G GL P+NY++M + + AD L L
Sbjct: 987 FTKGQIISVLD-KNDPDWWKGELNGVTGLFPTNYVKMTTADSDFSQQWCADPNSLDSLSL 1045
Query: 413 ANKPEGGFLIRISES 457
K G++ + E+
Sbjct: 1046 QEKKRQGYIHELIET 1060
>UniRef50_UPI000065CF8C Cluster: SH2 domain-containing protein 3C
(Novel SH2-containing protein 3).; n=1; Takifugu
rubripes|Rep: SH2 domain-containing protein 3C (Novel
SH2-containing protein 3). - Takifugu rubripes
Length = 580
Score = 40.7 bits (91), Expect = 0.033
Identities = 20/43 (46%), Positives = 28/43 (65%)
Frame = +2
Query: 353 MKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLS 481
+K+H+WY+G + AE L+ N G FLIR S S+ GDF L+
Sbjct: 31 LKSHAWYHGPVPWEVAESLVVN--HGEFLIRDSRSNHGDFVLT 71
>UniRef50_Q4SKC0 Cluster: Chromosome 13 SCAF14566, whole genome
shotgun sequence; n=2; Euteleostei|Rep: Chromosome 13
SCAF14566, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1249
Score = 40.7 bits (91), Expect = 0.033
Identities = 19/53 (35%), Positives = 28/53 (52%), Gaps = 1/53 (1%)
Frame = +2
Query: 359 NHSWYYGRITRADAEKLLANKP-EGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
N W+Y ++R AE L P +G FLIR E P F+++ K V+H +
Sbjct: 629 NEGWFYSDLSRGQAEDYLMRIPRDGAFLIRQREGEPDSFAITFKGDGKVKHCR 681
>UniRef50_Q4RIA8 Cluster: Chromosome 8 SCAF15044, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 8 SCAF15044, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 253
Score = 40.7 bits (91), Expect = 0.033
Identities = 18/48 (37%), Positives = 26/48 (54%)
Frame = +2
Query: 365 SWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
SWY+G ++R AE L E FL+R SES +S+++K H
Sbjct: 153 SWYHGSVSRQQAEAQLQRCREASFLVRDSESGTSKYSIALKTSQSCVH 200
>UniRef50_A4II17 Cluster: Putative uncharacterized protein; n=3;
Xenopus tropicalis|Rep: Putative uncharacterized protein
- Xenopus tropicalis (Western clawed frog) (Silurana
tropicalis)
Length = 379
Score = 40.7 bits (91), Expect = 0.033
Identities = 18/54 (33%), Positives = 32/54 (59%)
Frame = +2
Query: 353 MKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
++ WY+G++++ +AEK L N G F+IRI + ++ +SV+ QH K
Sbjct: 276 LQTQVWYHGKLSKLEAEKYLQNCKPGSFVIRIEQDI--EYFMSVRGSHSTQHLK 327
>UniRef50_O08526 Cluster: Vav-T; n=6; Euteleostomi|Rep: Vav-T - Mus
musculus (Mouse)
Length = 166
Score = 40.7 bits (91), Expect = 0.033
Identities = 21/61 (34%), Positives = 37/61 (60%), Gaps = 2/61 (3%)
Frame = +2
Query: 197 GSSKTRF-YCNR-R**AQF*KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYIQMKNHSW 370
G++K R+ +C R R + ++KILN + W+R E+ G+ G PSNY++ +++S
Sbjct: 106 GTAKARYDFCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYGRIGWFPSNYVE-EDYSE 164
Query: 371 Y 373
Y
Sbjct: 165 Y 165
>UniRef50_Q95ZL4 Cluster: Temporarily assigned gene name protein
163, isoform a; n=5; Caenorhabditis|Rep: Temporarily
assigned gene name protein 163, isoform a -
Caenorhabditis elegans
Length = 1112
Score = 40.7 bits (91), Expect = 0.033
Identities = 18/48 (37%), Positives = 29/48 (60%)
Frame = +2
Query: 344 YIQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVK 487
+++ + WY I+R A +L +KP G F++R S S PG F L++K
Sbjct: 833 FVKDTSKYWYKPTISREQAINMLRDKPPGTFVVRDSNSFPGAFGLALK 880
>UniRef50_Q8IR23 Cluster: CG9209-PA, isoform A; n=6;
Endopterygota|Rep: CG9209-PA, isoform A - Drosophila
melanogaster (Fruit fly)
Length = 954
Score = 40.7 bits (91), Expect = 0.033
Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 9/87 (10%)
Frame = +2
Query: 245 F*KNQVLKILN-MEDDMNWYRAELDGKEGLIPSNYIQMKNHS--------WYYGRITRAD 397
F K + + N M D W A G++G+I + + S W++ T+ +
Sbjct: 203 FQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVDDLDVSIDPNTVFPWFHPNCTKNE 262
Query: 398 AEKLLANKPEGGFLIRISESSPGDFSL 478
A +L G FL+R S++SPGD+SL
Sbjct: 263 AVDMLVKAGPGSFLVRPSDNSPGDYSL 289
Score = 39.1 bits (87), Expect = 0.099
Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Frame = +2
Query: 368 WYYGRITRADAEKLLANKPE-GGFLIRISESSPGDFSLSVKCPDGVQH 508
WY+GR+ R AE L + G +L+R S+ PG + LS G+ H
Sbjct: 84 WYHGRLDRYSAESRLRGSSKLGSYLVRESDRKPGSYVLSYYGRTGINH 131
>UniRef50_A7SKN8 Cluster: Predicted protein; n=3; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 155
Score = 40.7 bits (91), Expect = 0.033
Identities = 18/47 (38%), Positives = 30/47 (63%)
Frame = +2
Query: 347 IQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVK 487
+++ N WY+G+I R +AE++L P+G FL+R S FS+S +
Sbjct: 9 LEITNCPWYWGKINRFEAERVLDGLPDGTFLLRDSAQYQYLFSVSFR 55
>UniRef50_Q91ZA6 Cluster: Suppressor of cytokine signaling 4; n=10;
Amniota|Rep: Suppressor of cytokine signaling 4 - Mus
musculus (Mouse)
Length = 436
Score = 40.7 bits (91), Expect = 0.033
Identities = 22/63 (34%), Positives = 36/63 (57%)
Frame = +2
Query: 299 YRAELDGKEGLIPSNYIQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSL 478
+ ++D L+P + +Q+ N+ Y+G + + AE LL KPEG FL+R S FS+
Sbjct: 261 FHTQIDYVHCLVP-DLLQISNNPCYWGVMDKYAAEALLEGKPEGTFLLRDSAQEDYLFSV 319
Query: 479 SVK 487
S +
Sbjct: 320 SFR 322
>UniRef50_P29350 Cluster: Tyrosine-protein phosphatase non-receptor
type 6; n=39; Chordata|Rep: Tyrosine-protein phosphatase
non-receptor type 6 - Homo sapiens (Human)
Length = 595
Score = 40.7 bits (91), Expect = 0.033
Identities = 21/48 (43%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
Frame = +2
Query: 368 WYYGRITRADAEKLLANKP-EGGFLIRISESSPGDFSLSVKCPDGVQH 508
W++ ++ DAE LL + G FL R S + GDFSLSV+ D V H
Sbjct: 4 WFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTH 51
Score = 40.7 bits (91), Expect = 0.033
Identities = 23/51 (45%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
Frame = +2
Query: 335 PSNYIQMKNHSWYYGRITRADAEKLLANKPEGG-FLIRISESSPGDFSLSV 484
P N + WY+G ++ AE LL K E FL+R S S PGDF LSV
Sbjct: 99 PLNCSDPTSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSV 149
>UniRef50_O00160 Cluster: Myosin-If; n=30; Euteleostomi|Rep: Myosin-If
- Homo sapiens (Human)
Length = 1098
Score = 40.7 bits (91), Expect = 0.033
Identities = 16/33 (48%), Positives = 24/33 (72%)
Frame = +2
Query: 254 NQVLKILNMEDDMNWYRAELDGKEGLIPSNYIQ 352
N+V++IL MED W++ L G+EGL P NY++
Sbjct: 1065 NEVIEIL-MEDPSGWWKGRLHGQEGLFPGNYVE 1096
>UniRef50_UPI0000F1F44E Cluster: PREDICTED: similar to
Src-like-adaptor 2; n=1; Danio rerio|Rep: PREDICTED:
similar to Src-like-adaptor 2 - Danio rerio
Length = 193
Score = 40.3 bits (90), Expect = 0.043
Identities = 23/61 (37%), Positives = 34/61 (55%), Gaps = 2/61 (3%)
Frame = +2
Query: 335 PSNYIQMKNHSWYYGRITRADAEKLLA--NKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
P + + W++ I+R +AE+LL G FLIR S+S PG +SLSV+ G H
Sbjct: 18 PKPQLALFGPRWFFEGISRRNAEQLLMLPQNYSGCFLIRESQSFPGLYSLSVRQHSGQMH 77
Query: 509 S 511
+
Sbjct: 78 T 78
>UniRef50_UPI0000E811F8 Cluster: PREDICTED: similar to SH2D3C
protein; n=1; Gallus gallus|Rep: PREDICTED: similar to
SH2D3C protein - Gallus gallus
Length = 603
Score = 40.3 bits (90), Expect = 0.043
Identities = 20/54 (37%), Positives = 34/54 (62%)
Frame = +2
Query: 353 MKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
+++H+WY+GRI R +E L+ + G F+IR S +S GD+ L+ + + H K
Sbjct: 58 LRSHAWYHGRIPREVSESLV--QRNGDFIIRDSLTSVGDYVLTCRWRNEPLHFK 109
>UniRef50_Q8AVM4 Cluster: Sh2d3c-prov protein; n=5;
Euteleostomi|Rep: Sh2d3c-prov protein - Xenopus laevis
(African clawed frog)
Length = 676
Score = 40.3 bits (90), Expect = 0.043
Identities = 21/53 (39%), Positives = 33/53 (62%)
Frame = +2
Query: 356 KNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
++H+WY+GRI R +E L+ + G FLIR S +S GD+ L+ + + H K
Sbjct: 35 RSHAWYHGRIPREVSESLV--QRNGDFLIRDSLTSLGDYVLTCRWKNESLHFK 85
>UniRef50_Q4SBL7 Cluster: Chromosome 15 SCAF14667, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 15
SCAF14667, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 723
Score = 40.3 bits (90), Expect = 0.043
Identities = 18/48 (37%), Positives = 28/48 (58%)
Frame = +2
Query: 365 SWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
+WY G I R+ AE++L +G FLIR S++ G ++ SV +H
Sbjct: 621 TWYVGDIKRSQAEEMLRGTCDGTFLIRESQTQKGSYACSVVVDGDTKH 668
Score = 36.7 bits (81), Expect = 0.53
Identities = 14/46 (30%), Positives = 30/46 (65%), Gaps = 1/46 (2%)
Frame = +2
Query: 353 MKNHSWYYGRITRADAEKLLANKPEGGFLIRISESS-PGDFSLSVK 487
+ + WY+G I+R + + L + P+G FL+R + S G+++L+++
Sbjct: 357 LNDAEWYWGEISREEVNEKLRDTPDGTFLVRDASSKLEGEYTLTLR 402
>UniRef50_Q4RUJ4 Cluster: Chromosome 1 SCAF14995, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 1 SCAF14995, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 666
Score = 40.3 bits (90), Expect = 0.043
Identities = 18/50 (36%), Positives = 32/50 (64%)
Frame = +2
Query: 332 IPSNYIQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLS 481
+ N Q++ +WY+ R++R DAE+LL +G FL+R S ++ G + L+
Sbjct: 559 VAPNEEQLRRETWYHSRMSRRDAERLLIR--DGDFLVRESTTNLGQYVLT 606
>UniRef50_Q21055 Cluster: Protein tyrosine phosphatase protein 2;
n=2; Caenorhabditis|Rep: Protein tyrosine phosphatase
protein 2 - Caenorhabditis elegans
Length = 668
Score = 40.3 bits (90), Expect = 0.043
Identities = 23/58 (39%), Positives = 37/58 (63%), Gaps = 2/58 (3%)
Frame = +2
Query: 347 IQMKNHSWYYGRITRADAEKLLANKPEGG-FLIRISESSPGDFSLSVK-CPDGVQHSK 514
+ ++ +++YY R+ AE+LL E G FL+R SES+P +FS+SV+ D + H K
Sbjct: 4 LALRQYNFYY-RVNGEKAEELLKEYGEDGDFLLRYSESNPQNFSISVRVAEDKILHIK 60
Score = 37.9 bits (84), Expect = 0.23
Identities = 16/49 (32%), Positives = 26/49 (53%)
Frame = +2
Query: 362 HSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
+ W++G + + A KLL + G +L+R S+ PG +S K V H
Sbjct: 132 YRWWHGNLPASSANKLLQTEKNGTYLLRASQHIPGALVISAKTEGQVVH 180
>UniRef50_Q17AB7 Cluster: Putative uncharacterized protein; n=1;
Aedes aegypti|Rep: Putative uncharacterized protein -
Aedes aegypti (Yellowfever mosquito)
Length = 724
Score = 40.3 bits (90), Expect = 0.043
Identities = 18/52 (34%), Positives = 32/52 (61%)
Frame = +2
Query: 353 MKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
+++H+WY+G I R AE+++ + +G FL+R S PG++ L+ K H
Sbjct: 20 LRSHAWYHGPIPRQRAEEIV--QRDGDFLVRDCVSQPGNYVLTCKTKGPTLH 69
>UniRef50_Q5T4P1 Cluster: Phosphoinositide-3-kinase, regulatory
subunit 3 (P55, gamma) (Phosphoinositide-3-kinase,
regulatory subunit 3 (P55, gamma), isoform CRA_b); n=17;
Eutheria|Rep: Phosphoinositide-3-kinase, regulatory
subunit 3 (P55, gamma) (Phosphoinositide-3-kinase,
regulatory subunit 3 (P55, gamma), isoform CRA_b) - Homo
sapiens (Human)
Length = 402
Score = 40.3 bits (90), Expect = 0.043
Identities = 32/93 (34%), Positives = 41/93 (44%)
Frame = +2
Query: 254 NQVLKILNMEDDMNWYRAELDGKEGLIPSNYIQMKNHSWYYGRITRADAEKLLANKPEGG 433
N L I N + D N++ E D N +W+ I R AE LL KP+G
Sbjct: 268 NVWLGIKNEDADENYFINEED-------ENLPHYDEKTWFVEDINRVQAEDLLYGKPDGA 320
Query: 434 FLIRISESSPGDFSLSVKCPDGVQHSKY*ETPR 532
FLIR S S G ++ SV V+H T R
Sbjct: 321 FLIRES-SKKGCYACSVVADGEVKHCVIYSTAR 352
Score = 37.9 bits (84), Expect = 0.23
Identities = 15/48 (31%), Positives = 30/48 (62%), Gaps = 1/48 (2%)
Frame = +2
Query: 347 IQMKNHSWYYGRITRADAEKLLANKPEGGFLIR-ISESSPGDFSLSVK 487
+ +++ WY+G I+R + L + P+G FL+R S GD++L+++
Sbjct: 58 VSLQDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLR 105
>UniRef50_Q5T286 Cluster: Novel protein; n=8; Theria|Rep: Novel
protein - Homo sapiens (Human)
Length = 1601
Score = 40.3 bits (90), Expect = 0.043
Identities = 18/41 (43%), Positives = 28/41 (68%), Gaps = 3/41 (7%)
Frame = +2
Query: 254 NQVLKILNMED---DMNWYRAELDGKEGLIPSNYIQMKNHS 367
NQ LKIL +D + W+ AE++GK+G +PSNYI+ ++
Sbjct: 1561 NQKLKILEFKDVTGNTEWWLAEVNGKKGYVPSNYIRKTEYT 1601
>UniRef50_O15357 Cluster: Phosphatidylinositol-3,4,5-trisphosphate
5-phosphatase 2; n=24; Euteleostomi|Rep:
Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2
- Homo sapiens (Human)
Length = 1258
Score = 40.3 bits (90), Expect = 0.043
Identities = 22/51 (43%), Positives = 31/51 (60%), Gaps = 1/51 (1%)
Frame = +2
Query: 335 PSNYIQMKNHSWYYGRITRADAEKLLANK-PEGGFLIRISESSPGDFSLSV 484
P + + SWY+ ++RA AE+LLA +G FL+R SES G F+L V
Sbjct: 10 PGGALGSQAPSWYHRDLSRAAAEELLARAGRDGSFLVRDSESVAGAFALCV 60
>UniRef50_O00459 Cluster: Phosphatidylinositol 3-kinase regulatory
subunit beta; n=114; Euteleostomi|Rep:
Phosphatidylinositol 3-kinase regulatory subunit beta -
Homo sapiens (Human)
Length = 728
Score = 40.3 bits (90), Expect = 0.043
Identities = 20/51 (39%), Positives = 30/51 (58%)
Frame = +2
Query: 356 KNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
+ +WY G+I R AE++L+ K +G FLIR S S G ++ SV +H
Sbjct: 618 EERTWYVGKINRTQAEEMLSGKRDGTFLIRES-SQRGCYACSVVVDGDTKH 667
Score = 36.3 bits (80), Expect = 0.70
Identities = 14/46 (30%), Positives = 31/46 (67%), Gaps = 1/46 (2%)
Frame = +2
Query: 353 MKNHSWYYGRITRADAEKLLANKPEGGFLIRISESS-PGDFSLSVK 487
+++ WY+G I+R + + L + P+G FL+R + S G+++L+++
Sbjct: 325 LQDAEWYWGDISREEVNEKLRDTPDGTFLVRDASSKIQGEYTLTLR 370
>UniRef50_Q6XZF7 Cluster: Dynamin-binding protein; n=12; Eutheria|Rep:
Dynamin-binding protein - Homo sapiens (Human)
Length = 1577
Score = 40.3 bits (90), Expect = 0.043
Identities = 18/41 (43%), Positives = 28/41 (68%), Gaps = 3/41 (7%)
Frame = +2
Query: 254 NQVLKILNMED---DMNWYRAELDGKEGLIPSNYIQMKNHS 367
NQ LKIL +D + W+ AE++GK+G +PSNYI+ ++
Sbjct: 1537 NQKLKILEFKDVTGNTEWWLAEVNGKKGYVPSNYIRKTEYT 1577
>UniRef50_UPI0000D5672D Cluster: PREDICTED: similar to CG3208-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG3208-PA, isoform A - Tribolium castaneum
Length = 452
Score = 39.9 bits (89), Expect = 0.057
Identities = 20/49 (40%), Positives = 29/49 (59%), Gaps = 1/49 (2%)
Frame = +2
Query: 371 YYGRITRADAEKLLANKPEGGFLIRISESSPGDF-SLSVKCPDGVQHSK 514
Y+G IT A+ LL+ G +L+R S S+ G F +LS+K D + H K
Sbjct: 47 YHGAITHIQAQNLLSPHENGAYLVRSSRSANGQFHTLSLKFNDKIHHYK 95
>UniRef50_Q4SM05 Cluster: Chromosome 13 SCAF14555, whole genome
shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 13
SCAF14555, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 412
Score = 39.9 bits (89), Expect = 0.057
Identities = 21/47 (44%), Positives = 29/47 (61%)
Frame = +2
Query: 368 WYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
W+ G ITR DAE++L K G FLIR+S+ + + LS K D +H
Sbjct: 44 WFLGFITRKDAEEILREKELGCFLIRLSDKAIA-YILSYKGKDRCRH 89
>UniRef50_Q4H2S5 Cluster: Suppressor of cytokine signaling; n=1;
Ciona intestinalis|Rep: Suppressor of cytokine signaling
- Ciona intestinalis (Transparent sea squirt)
Length = 406
Score = 39.9 bits (89), Expect = 0.057
Identities = 18/65 (27%), Positives = 33/65 (50%)
Frame = +2
Query: 320 KEGLIPSNYIQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDG 499
++ + + + ++ WY+G +TR++AE L P G FL+R S SLS +
Sbjct: 238 RKNTLTNEFKKLAQQGWYWGPLTRSEAEDKLNETPNGSFLVRDSSDERYLLSLSFRSFGR 297
Query: 500 VQHSK 514
H++
Sbjct: 298 TLHTR 302
>UniRef50_UPI00015B50BA Cluster: PREDICTED: similar to suppressors
of cytokine signalling; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to suppressors of cytokine signalling
- Nasonia vitripennis
Length = 527
Score = 39.5 bits (88), Expect = 0.075
Identities = 20/50 (40%), Positives = 31/50 (62%)
Frame = +2
Query: 365 SWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
S+Y+G++ R +AE+LL K EG FL+R S FS+S + D H++
Sbjct: 360 SFYWGKMDRYEAERLLEGKQEGTFLLRDSAQEEFLFSVSFRKYDRSLHAR 409
>UniRef50_UPI0000F1F0F1 Cluster: PREDICTED: hypothetical protein;
n=2; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 213
Score = 39.5 bits (88), Expect = 0.075
Identities = 19/52 (36%), Positives = 27/52 (51%)
Frame = +2
Query: 332 IPSNYIQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVK 487
I + + + WY+G +T DA L PEG FL+R S F+LSV+
Sbjct: 44 ITTTFQHLNTSGWYWGGLTAGDARAALIGAPEGTFLVRDSSHPLYLFTLSVQ 95
>UniRef50_P52735 Cluster: Protein vav-2; n=28; Euteleostomi|Rep:
Protein vav-2 - Homo sapiens (Human)
Length = 878
Score = 39.5 bits (88), Expect = 0.075
Identities = 19/60 (31%), Positives = 30/60 (50%)
Frame = +2
Query: 335 PSNYIQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
PS I + W+ G + R + LL + G +LIR + F++S+K D V+H K
Sbjct: 662 PSREIDYTAYPWFAGNMERQQTDNLLKSHASGTYLIRERPAEAERFAISIKFNDEVKHIK 721
>UniRef50_UPI0000F201D0 Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 475
Score = 39.1 bits (87), Expect = 0.099
Identities = 18/54 (33%), Positives = 32/54 (59%)
Frame = +2
Query: 353 MKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSK 514
+++ +WY+G++ R E+LL +G FL+R S +S GD+ L+ + H K
Sbjct: 22 LRSQAWYHGQLQREATEQLLGR--DGEFLVRDSSTSAGDYVLTCMWKNQPMHFK 73
>UniRef50_UPI0000F1E232 Cluster: PREDICTED: hypothetical protein; n=2;
Danio rerio|Rep: PREDICTED: hypothetical protein - Danio
rerio
Length = 1330
Score = 39.1 bits (87), Expect = 0.099
Identities = 21/63 (33%), Positives = 32/63 (50%)
Frame = +2
Query: 323 EGLIPSNYIQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGV 502
E + S ++Q + WY I+R A +L +K G FLIR S S G + L++K
Sbjct: 1042 ESRLSSKFVQDSSKYWYKPGISRDQAIAVLKDKEAGCFLIRDSNSFQGAYGLALKVSTAP 1101
Query: 503 QHS 511
H+
Sbjct: 1102 AHT 1104
>UniRef50_UPI0000E45D4F Cluster: PREDICTED: similar to SH2 domain
containing 4B; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to SH2 domain containing 4B -
Strongylocentrotus purpuratus
Length = 470
Score = 39.1 bits (87), Expect = 0.099
Identities = 20/47 (42%), Positives = 29/47 (61%)
Frame = +2
Query: 368 WYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
W++G ITR AE LL K EG FL+R+S G ++LS + + +H
Sbjct: 355 WFHGIITRQQAEYLLFPKAEGHFLVRVSNRIWG-YALSFRDKERAKH 400
>UniRef50_Q4T639 Cluster: Chromosome undetermined SCAF8942, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF8942,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 431
Score = 39.1 bits (87), Expect = 0.099
Identities = 18/40 (45%), Positives = 27/40 (67%)
Frame = +2
Query: 365 SWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSV 484
SW+ G + R +AE+LL +P+G FL+R S S G ++ SV
Sbjct: 329 SWFVGDLKRGEAEELLLGRPDGSFLVRES-SRKGCYACSV 367
>UniRef50_Q4SMI9 Cluster: Chromosome 18 SCAF14547, whole genome
shotgun sequence; n=4; Clupeocephala|Rep: Chromosome 18
SCAF14547, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 609
Score = 39.1 bits (87), Expect = 0.099
Identities = 18/43 (41%), Positives = 28/43 (65%)
Frame = +2
Query: 353 MKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLS 481
+ +H+WY+G + R AE LL + G FL+R S S+P D+ L+
Sbjct: 16 LSSHAWYHGPLRREAAEALL--ERNGDFLVRDSSSTPRDYVLT 56
>UniRef50_Q4S131 Cluster: Chromosome 1 SCAF14770, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 1 SCAF14770, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 789
Score = 39.1 bits (87), Expect = 0.099
Identities = 20/40 (50%), Positives = 26/40 (65%), Gaps = 1/40 (2%)
Frame = +2
Query: 368 WYYGRITRADAEKLLANKP-EGGFLIRISESSPGDFSLSV 484
WY+ ITR+ AE LL+ +G FLIR SES G ++L V
Sbjct: 1 WYHSNITRSKAEDLLSKAARDGSFLIRDSESIQGAYALCV 40
>UniRef50_Q4RPN2 Cluster: Chromosome 12 SCAF15007, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 12 SCAF15007, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 868
Score = 39.1 bits (87), Expect = 0.099
Identities = 19/43 (44%), Positives = 29/43 (67%)
Frame = +2
Query: 353 MKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLS 481
+K+H+WY+G I +E L+ N G FLIR S+S+ G+F L+
Sbjct: 275 LKSHAWYHGPIPWEVSESLVVN--HGDFLIRDSQSNRGNFVLT 315
>UniRef50_A2BDR6 Cluster: SH2 domain containing 3C; n=5; Danio
rerio|Rep: SH2 domain containing 3C - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 635
Score = 39.1 bits (87), Expect = 0.099
Identities = 20/45 (44%), Positives = 29/45 (64%)
Frame = +2
Query: 353 MKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVK 487
+ +H WY+GRI +E L+ + EG FLIR S SS GD+ L+ +
Sbjct: 45 LSSHGWYHGRIPWEVSESLV--QQEGDFLIRDSLSSIGDYVLTCR 87
>UniRef50_Q9Y1Y2 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 743
Score = 39.1 bits (87), Expect = 0.099
Identities = 20/50 (40%), Positives = 30/50 (60%), Gaps = 4/50 (8%)
Frame = +2
Query: 368 WYYGRITRADAEKLLANKP----EGGFLIRISESSPGDFSLSVKCPDGVQ 505
WY+G+ITR +A L++ P EG FL+R S +PG + L++ VQ
Sbjct: 10 WYHGKITRENAAHLVSQGPITRREGLFLVRESTRTPGSYVLTLWAKGNVQ 59
>UniRef50_Q54U31 Cluster: SH2 domain-containing protein; n=1;
Dictyostelium discoideum AX4|Rep: SH2 domain-containing
protein - Dictyostelium discoideum AX4
Length = 744
Score = 39.1 bits (87), Expect = 0.099
Identities = 23/80 (28%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Frame = +2
Query: 257 QVLKILNMEDDMNWYRAELDGKEGLIP-SNYIQMKNHSWYYGRITRADAEKLLANKPEGG 433
QV+ + + W+ + + G+ N ++ W++G I R A L+ EG
Sbjct: 603 QVVTMERFDKVSKWFGSFFEPNTGIETIDNINKLSAKIWFHGDIVREQATSRLSKAAEGA 662
Query: 434 FLIRISESSPG--DFSLSVK 487
FLIR+S + P F+LS+K
Sbjct: 663 FLIRLSSTEPKTCPFTLSMK 682
>UniRef50_A7RRM1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 274
Score = 39.1 bits (87), Expect = 0.099
Identities = 18/40 (45%), Positives = 26/40 (65%)
Frame = +2
Query: 368 WYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVK 487
WY +ITR A +L +K G F++R S+S PG + L+VK
Sbjct: 4 WYKPKITRDQAINVLKDKEPGLFVVRDSQSFPGAYGLAVK 43
>UniRef50_O75159 Cluster: Suppressor of cytokine signaling 5; n=31;
Euteleostomi|Rep: Suppressor of cytokine signaling 5 -
Homo sapiens (Human)
Length = 536
Score = 39.1 bits (87), Expect = 0.099
Identities = 22/60 (36%), Positives = 35/60 (58%)
Frame = +2
Query: 308 ELDGKEGLIPSNYIQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVK 487
++D L+P + +Q+ + Y+G + R +AE LL KPEG FL+R S FS+S +
Sbjct: 362 QIDYIHCLVP-DLLQITGNPCYWGVMDRYEAEALLEGKPEGTFLLRDSAQEDYLFSVSFR 420
>UniRef50_Q2I6J0 Cluster: Phosphatidylinositol-3,4,5-trisphosphate
5-phosphatase 2B; n=6; Euteleostomi|Rep:
Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase
2B - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 1226
Score = 39.1 bits (87), Expect = 0.099
Identities = 20/43 (46%), Positives = 28/43 (65%), Gaps = 1/43 (2%)
Frame = +2
Query: 353 MKNHSWYYGRITRADAEKLLANKP-EGGFLIRISESSPGDFSL 478
M WY+ I+R AE+LLA+ +G FL+R SES PG ++L
Sbjct: 1 MTGAPWYHRDISRVRAEELLAHAGIDGSFLVRDSESVPGAYAL 43
>UniRef50_UPI000155BC71 Cluster: PREDICTED: similar to inositol
polyphosphate 5- phosphatase; n=1; Ornithorhynchus
anatinus|Rep: PREDICTED: similar to inositol
polyphosphate 5- phosphatase - Ornithorhynchus anatinus
Length = 1019
Score = 38.7 bits (86), Expect = 0.13
Identities = 19/42 (45%), Positives = 27/42 (64%), Gaps = 1/42 (2%)
Frame = +2
Query: 362 HSWYYGRITRADAEKLLANK-PEGGFLIRISESSPGDFSLSV 484
H W +G ITR+ AE+LL+ +G FL+R SES ++L V
Sbjct: 3 HCWNHGNITRSKAEELLSKTGKDGSFLVRASESISRAYALCV 44
>UniRef50_UPI0000F1F169 Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 720
Score = 38.7 bits (86), Expect = 0.13
Identities = 20/53 (37%), Positives = 28/53 (52%)
Frame = +2
Query: 350 QMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
+++ WY+G + DAE L KP+G FL+R S SLS + GV H
Sbjct: 533 ELERCGWYWGPMNWEDAEMKLRGKPDGSFLVRDSSDPRYILSLSFR-SQGVTH 584
>UniRef50_UPI0000D56397 Cluster: PREDICTED: similar to Tensin-1; n=1;
Tribolium castaneum|Rep: PREDICTED: similar to Tensin-1 -
Tribolium castaneum
Length = 1487
Score = 38.7 bits (86), Expect = 0.13
Identities = 16/48 (33%), Positives = 29/48 (60%)
Frame = +2
Query: 344 YIQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVK 487
+++ + WY I+R +A +L +P G F++R S S PG F +++K
Sbjct: 1206 FVRDTSKYWYKPTISREEAISMLREQPPGTFVVRDSNSFPGAFGMALK 1253
>UniRef50_UPI00004992D9 Cluster: hypothetical protein 68.t00030;
n=1; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical
protein 68.t00030 - Entamoeba histolytica HM-1:IMSS
Length = 566
Score = 38.7 bits (86), Expect = 0.13
Identities = 14/36 (38%), Positives = 25/36 (69%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYIQ 352
F K ++KI + +D+ W+ E++GK G +PSN++Q
Sbjct: 531 FKKGDIIKIYSTDDE--WFEGEINGKRGFVPSNFLQ 564
>UniRef50_UPI000065FE19 Cluster: SHC-transforming protein 1 (SH2
domain protein C1) (Src homology 2
domain-containing-transforming protein C1).; n=2;
Euteleostomi|Rep: SHC-transforming protein 1 (SH2 domain
protein C1) (Src homology 2
domain-containing-transforming protein C1). - Takifugu
rubripes
Length = 526
Score = 38.7 bits (86), Expect = 0.13
Identities = 16/44 (36%), Positives = 31/44 (70%)
Frame = +2
Query: 350 QMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLS 481
Q++ +W++G ++R +AE+LL +G FL+R S ++PG + L+
Sbjct: 426 QLQCEAWFHGGLSRKEAERLLTR--DGDFLVRESGTTPGQYVLT 467
>UniRef50_Q4S3B2 Cluster: Chromosome 4 SCAF14752, whole genome
shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 4
SCAF14752, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 721
Score = 38.7 bits (86), Expect = 0.13
Identities = 19/52 (36%), Positives = 30/52 (57%)
Frame = +2
Query: 353 MKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQH 508
+++H WY+G I R +E L+ G FL+R S +S GDF L+ + + H
Sbjct: 32 IRSHGWYHGHIPREVSETLVLR--NGDFLVRDSLTSVGDFVLTCRWDNEALH 81
>UniRef50_Q4RQV0 Cluster: Chromosome 2 SCAF15004, whole genome
shotgun sequence; n=5; Euteleostomi|Rep: Chromosome 2
SCAF15004, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 687
Score = 38.7 bits (86), Expect = 0.13
Identities = 17/38 (44%), Positives = 25/38 (65%)
Frame = +2
Query: 242 QF*KNQVLKILNMEDDMNWYRAELDGKEGLIPSNYIQM 355
QF K ++ IL + D NWY EL+G G +P++YIQ+
Sbjct: 29 QFSKGDII-ILRRKVDDNWYHGELNGCHGFLPASYIQL 65
>UniRef50_Q4RP74 Cluster: Chromosome 1 SCAF15008, whole genome
shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 1
SCAF15008, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 968
Score = 38.7 bits (86), Expect = 0.13
Identities = 20/48 (41%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
Frame = +2
Query: 338 SNYIQMKNHSWYYGRITRADAEKLLANK-PEGGFLIRISESSPGDFSL 478
S M WY+ I+R AE+LLA +G +L+R SES PG ++L
Sbjct: 4 STLTAMATAVWYHRDISRVQAEELLARAGKDGSYLVRDSESVPGAYAL 51
>UniRef50_Q4RIB1 Cluster: Chromosome 8 SCAF15044, whole genome
shotgun sequence; n=3; Percomorpha|Rep: Chromosome 8
SCAF15044, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 480
Score = 38.7 bits (86), Expect = 0.13
Identities = 16/44 (36%), Positives = 31/44 (70%)
Frame = +2
Query: 350 QMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLS 481
Q++ +W++G ++R +AE+LL +G FL+R S ++PG + L+
Sbjct: 379 QLQCEAWFHGGLSRKEAERLLTR--DGDFLVRESGTTPGQYVLT 420
>UniRef50_A7T8K3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 402
Score = 38.7 bits (86), Expect = 0.13
Identities = 19/54 (35%), Positives = 28/54 (51%)
Frame = +2
Query: 356 KNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVKCPDGVQHSKY 517
+N WY I R ++L EG F +R S+S PG +L+V+ P V S +
Sbjct: 266 QNECWYMPGIPREFIMEMLQASEEGSFFVRDSQSKPGCHALTVRVPTEVHASGF 319
>UniRef50_A4F2N7 Cluster: Mt-tensin-b; n=2; Molgula tectiformis|Rep:
Mt-tensin-b - Molgula tectiformis
Length = 1177
Score = 38.7 bits (86), Expect = 0.13
Identities = 17/51 (33%), Positives = 28/51 (54%)
Frame = +2
Query: 335 PSNYIQMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLSVK 487
P ++ + WY ITR A +L ++P G F++R S PG + L++K
Sbjct: 887 PPLFVHDVQNLWYKPDITREQALDMLRHRPAGSFVVRDSRCFPGAYGLALK 937
>UniRef50_Q5T185 Cluster: SHC (Src homology 2 domain containing)
transforming protein 1 (SHC (Src homology 2 domain
containing) transforming protein 1, isoform CRA_c); n=8;
Theria|Rep: SHC (Src homology 2 domain containing)
transforming protein 1 (SHC (Src homology 2 domain
containing) transforming protein 1, isoform CRA_c) -
Homo sapiens (Human)
Length = 473
Score = 38.7 bits (86), Expect = 0.13
Identities = 16/44 (36%), Positives = 30/44 (68%)
Frame = +2
Query: 350 QMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLS 481
Q++ W++G+++R +AE LL + G FL+R S ++PG + L+
Sbjct: 372 QLRGEPWFHGKLSRREAEALL--QLNGDFLVRESTTTPGQYVLT 413
>UniRef50_Q59HB0 Cluster: SHC (Src homology 2 domain containing)
transforming protein 1 isoform p66Shc variant; n=9;
Tetrapoda|Rep: SHC (Src homology 2 domain containing)
transforming protein 1 isoform p66Shc variant - Homo
sapiens (Human)
Length = 377
Score = 38.7 bits (86), Expect = 0.13
Identities = 16/44 (36%), Positives = 30/44 (68%)
Frame = +2
Query: 350 QMKNHSWYYGRITRADAEKLLANKPEGGFLIRISESSPGDFSLS 481
Q++ W++G+++R +AE LL + G FL+R S ++PG + L+
Sbjct: 261 QLRGEPWFHGKLSRREAEALL--QLNGDFLVRESTTTPGQYVLT 302
>UniRef50_A4R2P0 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 1040
Score = 38.7 bits (86), Expect = 0.13
Identities = 19/40 (47%), Positives = 27/40 (67%), Gaps = 3/40 (7%)
Frame = +2
Query: 245 F*KNQVLKILNMEDDMNWYRAEL---DGKEGLIPSNYIQM 355
F K VL +L +DD W+ AE+ DG+ GL+PSNY+Q+
Sbjct: 1001 FAKGDVLAVLRHQDD-GWWEAEVHGGDGQVGLVPSNYLQV 1039
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 626,906,264
Number of Sequences: 1657284
Number of extensions: 11547903
Number of successful extensions: 24919
Number of sequences better than 10.0: 476
Number of HSP's better than 10.0 without gapping: 23724
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 24794
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 53719013270
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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