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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= NV021192
         (685 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

EF629347-1|ABR15764.1| 1998|Homo sapiens Nav1.5 Na+ channel prot...    31   2.9  
EF629346-1|ABR15763.1| 2016|Homo sapiens Nav1.5 Na+ channel prot...    31   2.9  
EF179185-1|ABN05288.1| 2015|Homo sapiens sodium channel, voltage...    31   2.9  
DQ784809-1|ABQ01244.1| 2016|Homo sapiens sodium channel protein ...    31   2.9  
AY148488-1|AAN61120.1| 2015|Homo sapiens cardiac sodium channel ...    31   2.9  
AB208866-1|BAD92103.1| 1576|Homo sapiens voltage-gated sodium ch...    31   2.9  
AB158470-1|BAD12085.1| 1962|Homo sapiens TTX-resistant sodium ch...    31   2.9  
AB158469-1|BAD12084.1| 2016|Homo sapiens TTX-resistant sodium ch...    31   2.9  
X53416-1|CAA37495.1| 2647|Homo sapiens protein ( Human mRNA for ...    30   8.8  
L44140-1|AAA92644.1| 2647|Homo sapiens filamin protein.                30   8.8  
BX936346-3|CAI43225.1| 2647|Homo sapiens filamin A, alpha (actin...    30   8.8  
BX936346-2|CAI43227.1| 2639|Homo sapiens filamin A, alpha (actin...    30   8.8  
BX936346-1|CAI43226.1| 2607|Homo sapiens filamin A, alpha (actin...    30   8.8  
BX664723-3|CAI43197.1| 2647|Homo sapiens filamin A, alpha (actin...    30   8.8  
BX664723-2|CAI43199.1| 2639|Homo sapiens filamin A, alpha (actin...    30   8.8  
BX664723-1|CAI43198.1| 2607|Homo sapiens filamin A, alpha (actin...    30   8.8  
BC067111-1|AAH67111.1|  983|Homo sapiens FLNA protein protein.         30   8.8  
BC041179-1|AAH41179.1|  177|Homo sapiens Similar to filamin C, g...    30   8.8  
BC014654-1|AAH14654.1|  838|Homo sapiens FLNA protein protein.         30   8.8  
AK090427-1|BAC03408.1| 2651|Homo sapiens FLJ00343 protein protein.     30   8.8  
AK074048-1|BAB84874.1| 1455|Homo sapiens FLJ00119 protein protein.     30   8.8  
AB191260-1|BAD52436.1| 2620|Homo sapiens filamin A protein.            30   8.8  
AB191259-1|BAD52435.1| 2612|Homo sapiens filamin A protein.            30   8.8  

>EF629347-1|ABR15764.1| 1998|Homo sapiens Nav1.5 Na+ channel
           protein.
          Length = 1998

 Score = 31.5 bits (68), Expect = 2.9
 Identities = 20/45 (44%), Positives = 25/45 (55%), Gaps = 1/45 (2%)
 Frame = -2

Query: 510 GQWFDFQTIQHGRAG*SRAHHTGLLVE-PLFSISSRGNPLLPTTS 379
           G   DF   ++  AG S +HHT LLV  PL   S++G P  P TS
Sbjct: 538 GSEADFADDENSTAGESESHHTSLLVPWPLRRTSAQGQP-SPGTS 581


>EF629346-1|ABR15763.1| 2016|Homo sapiens Nav1.5 Na+ channel
           protein.
          Length = 2016

 Score = 31.5 bits (68), Expect = 2.9
 Identities = 20/45 (44%), Positives = 25/45 (55%), Gaps = 1/45 (2%)
 Frame = -2

Query: 510 GQWFDFQTIQHGRAG*SRAHHTGLLVE-PLFSISSRGNPLLPTTS 379
           G   DF   ++  AG S +HHT LLV  PL   S++G P  P TS
Sbjct: 538 GSEADFADDENSTAGESESHHTSLLVPWPLRRTSAQGQP-SPGTS 581


>EF179185-1|ABN05288.1| 2015|Homo sapiens sodium channel,
           voltage-gated, type V, alpha (long QT syndrome 3)
           protein.
          Length = 2015

 Score = 31.5 bits (68), Expect = 2.9
 Identities = 20/45 (44%), Positives = 25/45 (55%), Gaps = 1/45 (2%)
 Frame = -2

Query: 510 GQWFDFQTIQHGRAG*SRAHHTGLLVE-PLFSISSRGNPLLPTTS 379
           G   DF   ++  AG S +HHT LLV  PL   S++G P  P TS
Sbjct: 538 GSEADFADDENSTAGESESHHTSLLVPWPLRRTSAQGQP-SPGTS 581


>DQ784809-1|ABQ01244.1| 2016|Homo sapiens sodium channel protein
           type V alpha subunit protein.
          Length = 2016

 Score = 31.5 bits (68), Expect = 2.9
 Identities = 20/45 (44%), Positives = 25/45 (55%), Gaps = 1/45 (2%)
 Frame = -2

Query: 510 GQWFDFQTIQHGRAG*SRAHHTGLLVE-PLFSISSRGNPLLPTTS 379
           G   DF   ++  AG S +HHT LLV  PL   S++G P  P TS
Sbjct: 538 GSEADFADDENSTAGESESHHTSLLVPWPLRRTSAQGQP-SPGTS 581


>AY148488-1|AAN61120.1| 2015|Homo sapiens cardiac sodium channel
           alpha subunit Nav1.5 protein.
          Length = 2015

 Score = 31.5 bits (68), Expect = 2.9
 Identities = 20/45 (44%), Positives = 25/45 (55%), Gaps = 1/45 (2%)
 Frame = -2

Query: 510 GQWFDFQTIQHGRAG*SRAHHTGLLVE-PLFSISSRGNPLLPTTS 379
           G   DF   ++  AG S +HHT LLV  PL   S++G P  P TS
Sbjct: 538 GSEADFADDENSTAGESESHHTSLLVPWPLRRTSAQGQP-SPGTS 581


>AB208866-1|BAD92103.1| 1576|Homo sapiens voltage-gated sodium
           channel type V alpha isoform b variant protein.
          Length = 1576

 Score = 31.5 bits (68), Expect = 2.9
 Identities = 20/45 (44%), Positives = 25/45 (55%), Gaps = 1/45 (2%)
 Frame = -2

Query: 510 GQWFDFQTIQHGRAG*SRAHHTGLLVE-PLFSISSRGNPLLPTTS 379
           G   DF   ++  AG S +HHT LLV  PL   S++G P  P TS
Sbjct: 117 GSEADFADDENSTAGESESHHTSLLVPWPLRRTSAQGQP-SPGTS 160


>AB158470-1|BAD12085.1| 1962|Homo sapiens TTX-resistant sodium
           channel splicing variant protein.
          Length = 1962

 Score = 31.5 bits (68), Expect = 2.9
 Identities = 20/45 (44%), Positives = 25/45 (55%), Gaps = 1/45 (2%)
 Frame = -2

Query: 510 GQWFDFQTIQHGRAG*SRAHHTGLLVE-PLFSISSRGNPLLPTTS 379
           G   DF   ++  AG S +HHT LLV  PL   S++G P  P TS
Sbjct: 538 GSEADFADDENSTAGESESHHTSLLVPWPLRRTSAQGQP-SPGTS 581


>AB158469-1|BAD12084.1| 2016|Homo sapiens TTX-resistant sodium
           channel protein.
          Length = 2016

 Score = 31.5 bits (68), Expect = 2.9
 Identities = 20/45 (44%), Positives = 25/45 (55%), Gaps = 1/45 (2%)
 Frame = -2

Query: 510 GQWFDFQTIQHGRAG*SRAHHTGLLVE-PLFSISSRGNPLLPTTS 379
           G   DF   ++  AG S +HHT LLV  PL   S++G P  P TS
Sbjct: 538 GSEADFADDENSTAGESESHHTSLLVPWPLRRTSAQGQP-SPGTS 581


>X53416-1|CAA37495.1| 2647|Homo sapiens protein ( Human mRNA for
            actin-binding protein (filamin) (ABP-280). ).
          Length = 2647

 Score = 29.9 bits (64), Expect = 8.8
 Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
 Frame = -3

Query: 683  RLIQGHSYR*TIRIPYKSLMRSTGAPLHGAHSCG-A*STKTVIHGSSL 543
            RL+  HS   T  +   SL ++T AP HGA   G A ++K V  G  L
Sbjct: 2520 RLVSNHSLHETSSVFVDSLTKATCAPQHGAPGPGPADASKVVAKGLGL 2567


>L44140-1|AAA92644.1| 2647|Homo sapiens filamin protein.
          Length = 2647

 Score = 29.9 bits (64), Expect = 8.8
 Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
 Frame = -3

Query: 683  RLIQGHSYR*TIRIPYKSLMRSTGAPLHGAHSCG-A*STKTVIHGSSL 543
            RL+  HS   T  +   SL ++T AP HGA   G A ++K V  G  L
Sbjct: 2520 RLVSNHSLHETSSVFVDSLTKATCAPQHGAPGPGPADASKVVAKGLGL 2567


>BX936346-3|CAI43225.1| 2647|Homo sapiens filamin A, alpha (actin
            binding protein 280) protein.
          Length = 2647

 Score = 29.9 bits (64), Expect = 8.8
 Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
 Frame = -3

Query: 683  RLIQGHSYR*TIRIPYKSLMRSTGAPLHGAHSCG-A*STKTVIHGSSL 543
            RL+  HS   T  +   SL ++T AP HGA   G A ++K V  G  L
Sbjct: 2520 RLVSNHSLHETSSVFVDSLTKATCAPQHGAPGPGPADASKVVAKGLGL 2567


>BX936346-2|CAI43227.1| 2639|Homo sapiens filamin A, alpha (actin
            binding protein 280) protein.
          Length = 2639

 Score = 29.9 bits (64), Expect = 8.8
 Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
 Frame = -3

Query: 683  RLIQGHSYR*TIRIPYKSLMRSTGAPLHGAHSCG-A*STKTVIHGSSL 543
            RL+  HS   T  +   SL ++T AP HGA   G A ++K V  G  L
Sbjct: 2512 RLVSNHSLHETSSVFVDSLTKATCAPQHGAPGPGPADASKVVAKGLGL 2559


>BX936346-1|CAI43226.1| 2607|Homo sapiens filamin A, alpha (actin
            binding protein 280) protein.
          Length = 2607

 Score = 29.9 bits (64), Expect = 8.8
 Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
 Frame = -3

Query: 683  RLIQGHSYR*TIRIPYKSLMRSTGAPLHGAHSCG-A*STKTVIHGSSL 543
            RL+  HS   T  +   SL ++T AP HGA   G A ++K V  G  L
Sbjct: 2480 RLVSNHSLHETSSVFVDSLTKATCAPQHGAPGPGPADASKVVAKGLGL 2527


>BX664723-3|CAI43197.1| 2647|Homo sapiens filamin A, alpha (actin
            binding protein 280) protein.
          Length = 2647

 Score = 29.9 bits (64), Expect = 8.8
 Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
 Frame = -3

Query: 683  RLIQGHSYR*TIRIPYKSLMRSTGAPLHGAHSCG-A*STKTVIHGSSL 543
            RL+  HS   T  +   SL ++T AP HGA   G A ++K V  G  L
Sbjct: 2520 RLVSNHSLHETSSVFVDSLTKATCAPQHGAPGPGPADASKVVAKGLGL 2567


>BX664723-2|CAI43199.1| 2639|Homo sapiens filamin A, alpha (actin
            binding protein 280) protein.
          Length = 2639

 Score = 29.9 bits (64), Expect = 8.8
 Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
 Frame = -3

Query: 683  RLIQGHSYR*TIRIPYKSLMRSTGAPLHGAHSCG-A*STKTVIHGSSL 543
            RL+  HS   T  +   SL ++T AP HGA   G A ++K V  G  L
Sbjct: 2512 RLVSNHSLHETSSVFVDSLTKATCAPQHGAPGPGPADASKVVAKGLGL 2559


>BX664723-1|CAI43198.1| 2607|Homo sapiens filamin A, alpha (actin
            binding protein 280) protein.
          Length = 2607

 Score = 29.9 bits (64), Expect = 8.8
 Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
 Frame = -3

Query: 683  RLIQGHSYR*TIRIPYKSLMRSTGAPLHGAHSCG-A*STKTVIHGSSL 543
            RL+  HS   T  +   SL ++T AP HGA   G A ++K V  G  L
Sbjct: 2480 RLVSNHSLHETSSVFVDSLTKATCAPQHGAPGPGPADASKVVAKGLGL 2527


>BC067111-1|AAH67111.1|  983|Homo sapiens FLNA protein protein.
          Length = 983

 Score = 29.9 bits (64), Expect = 8.8
 Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
 Frame = -3

Query: 683 RLIQGHSYR*TIRIPYKSLMRSTGAPLHGAHSCG-A*STKTVIHGSSL 543
           RL+  HS   T  +   SL ++T AP HGA   G A ++K V  G  L
Sbjct: 856 RLVSNHSLHETSSVFVDSLTKATCAPQHGAPGPGPADASKVVAKGLGL 903


>BC041179-1|AAH41179.1|  177|Homo sapiens Similar to filamin C,
           gamma (actin binding protein 280) protein.
          Length = 177

 Score = 29.9 bits (64), Expect = 8.8
 Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
 Frame = -3

Query: 683 RLIQGHSYR*TIRIPYKSLMRSTGAPLHGAHSCG-A*STKTVIHGSSL 543
           RL+  HS   T  +   SL ++T AP HGA   G A ++K V  G  L
Sbjct: 50  RLVSNHSLHETSSVFVDSLTKATCAPQHGAPGPGPADASKVVAKGLGL 97


>BC014654-1|AAH14654.1|  838|Homo sapiens FLNA protein protein.
          Length = 838

 Score = 29.9 bits (64), Expect = 8.8
 Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
 Frame = -3

Query: 683 RLIQGHSYR*TIRIPYKSLMRSTGAPLHGAHSCG-A*STKTVIHGSSL 543
           RL+  HS   T  +   SL ++T AP HGA   G A ++K V  G  L
Sbjct: 711 RLVSNHSLHETSSVFVDSLTKATCAPQHGAPGPGPADASKVVAKGLGL 758


>AK090427-1|BAC03408.1| 2651|Homo sapiens FLJ00343 protein protein.
          Length = 2651

 Score = 29.9 bits (64), Expect = 8.8
 Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
 Frame = -3

Query: 683  RLIQGHSYR*TIRIPYKSLMRSTGAPLHGAHSCG-A*STKTVIHGSSL 543
            RL+  HS   T  +   SL ++T AP HGA   G A ++K V  G  L
Sbjct: 2524 RLVSNHSLHETSSVFVDSLTKATCAPQHGAPGPGPADASKVVAKGLGL 2571


>AK074048-1|BAB84874.1| 1455|Homo sapiens FLJ00119 protein protein.
          Length = 1455

 Score = 29.9 bits (64), Expect = 8.8
 Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
 Frame = -3

Query: 683  RLIQGHSYR*TIRIPYKSLMRSTGAPLHGAHSCG-A*STKTVIHGSSL 543
            RL+  HS   T  +   SL ++T AP HGA   G A ++K V  G  L
Sbjct: 1328 RLVSNHSLHETSSVFVDSLTKATCAPQHGAPGPGPADASKVVAKGLGL 1375


>AB191260-1|BAD52436.1| 2620|Homo sapiens filamin A protein.
          Length = 2620

 Score = 29.9 bits (64), Expect = 8.8
 Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
 Frame = -3

Query: 683  RLIQGHSYR*TIRIPYKSLMRSTGAPLHGAHSCG-A*STKTVIHGSSL 543
            RL+  HS   T  +   SL ++T AP HGA   G A ++K V  G  L
Sbjct: 2493 RLVSNHSLHETSSVFVDSLTKATCAPQHGAPGPGPADASKVVAKGLGL 2540


>AB191259-1|BAD52435.1| 2612|Homo sapiens filamin A protein.
          Length = 2612

 Score = 29.9 bits (64), Expect = 8.8
 Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
 Frame = -3

Query: 683  RLIQGHSYR*TIRIPYKSLMRSTGAPLHGAHSCG-A*STKTVIHGSSL 543
            RL+  HS   T  +   SL ++T AP HGA   G A ++K V  G  L
Sbjct: 2485 RLVSNHSLHETSSVFVDSLTKATCAPQHGAPGPGPADASKVVAKGLGL 2532


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 106,855,548
Number of Sequences: 237096
Number of extensions: 2506487
Number of successful extensions: 6226
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 5953
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6220
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7783251346
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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