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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= NV021185
         (765 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_P08249 Cluster: Malate dehydrogenase, mitochondrial pre...   115   1e-24
UniRef50_P40926 Cluster: Malate dehydrogenase, mitochondrial pre...   115   1e-24
UniRef50_Q9SN86 Cluster: Malate dehydrogenase, chloroplast precu...   109   7e-23
UniRef50_A3BMG8 Cluster: Putative uncharacterized protein; n=3; ...   106   7e-22
UniRef50_A2QMH9 Cluster: Malate dehydrogenase; n=7; Fungi/Metazo...   104   2e-21
UniRef50_A7SQS1 Cluster: Predicted protein; n=1; Nematostella ve...   103   6e-21
UniRef50_Q9Y7R8 Cluster: Malate dehydrogenase; n=13; Dikarya|Rep...    97   3e-19
UniRef50_Q42972 Cluster: Malate dehydrogenase, glyoxysomal precu...    97   3e-19
UniRef50_Q75AT4 Cluster: ADL164Cp; n=2; Saccharomycetales|Rep: A...    90   5e-17
UniRef50_Q6BM17 Cluster: Malate dehydrogenase; n=4; Eukaryota|Re...    89   1e-16
UniRef50_Q6FL22 Cluster: Malate dehydrogenase; n=1; Candida glab...    88   2e-16
UniRef50_A7TL95 Cluster: Putative uncharacterized protein; n=1; ...    88   3e-16
UniRef50_P22133 Cluster: Malate dehydrogenase, cytoplasmic; n=3;...    88   3e-16
UniRef50_Q9VU29 Cluster: Malate dehydrogenase; n=5; Protostomia|...    84   4e-15
UniRef50_A7TSF5 Cluster: Putative uncharacterized protein; n=1; ...    81   2e-14
UniRef50_Q4Q3J3 Cluster: Malate dehydrogenase, putative; n=3; Le...    78   3e-13
UniRef50_P32419 Cluster: Malate dehydrogenase, peroxisomal; n=24...    78   3e-13
UniRef50_Q9VU28 Cluster: Malate dehydrogenase; n=3; Sophophora|R...    77   5e-13
UniRef50_Q6CP51 Cluster: Similar to sp|P22133 Saccharomyces cere...    77   5e-13
UniRef50_Q86DP2 Cluster: Malate dehydrogenase; n=11; Fungi/Metaz...    76   8e-13
UniRef50_Q4QDF0 Cluster: Glycosomal malate dehydrogenase; n=9; T...    76   1e-12
UniRef50_UPI00005A0834 Cluster: PREDICTED: similar to Malate deh...    68   3e-10
UniRef50_Q017A6 Cluster: Malate dehydrogenase; n=2; cellular org...    65   2e-09
UniRef50_Q6VVP7 Cluster: Malate dehydrogenase; n=6; Plasmodium|R...    63   8e-09
UniRef50_Q5ENS5 Cluster: Malate dehydrogenase; n=1; Heterocapsa ...    60   4e-08
UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular o...    58   2e-07
UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Re...    57   4e-07
UniRef50_O08349 Cluster: Malate dehydrogenase; n=1; Archaeoglobu...    57   4e-07
UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3; Acti...    57   6e-07
UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2...    57   6e-07
UniRef50_UPI0000D571DB Cluster: PREDICTED: similar to CG7998-PA;...    54   4e-06
UniRef50_UPI00015BB1FC Cluster: malate dehydrogenase (NAD); n=1;...    54   5e-06
UniRef50_Q8ZVB2 Cluster: Malate dehydrogenase; n=14; Thermoprote...    53   7e-06
UniRef50_UPI00015B4591 Cluster: PREDICTED: similar to mitochondr...    53   9e-06
UniRef50_A6Q7S2 Cluster: Malate dehydrogenase, NAD-dependent; n=...    53   9e-06
UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=...    53   9e-06
UniRef50_UPI0000DB76D8 Cluster: PREDICTED: similar to CG7998-PA;...    52   2e-05
UniRef50_P11386 Cluster: Malate dehydrogenase; n=6; Sulfolobacea...    52   2e-05
UniRef50_A4L2P0 Cluster: L-lactate dehydrogenase; n=4; Lactobaci...    51   3e-05
UniRef50_Q4Q3J5 Cluster: Malate dehydrogenase, putative; n=5; Tr...    51   4e-05
UniRef50_Q64P62 Cluster: Malate dehydrogenase; n=28; Bacteroidet...    50   5e-05
UniRef50_Q6A9C3 Cluster: L-lactate dehydrogenase; n=2; Propionib...    50   5e-05
UniRef50_Q979N9 Cluster: Malate dehydrogenase; n=4; Thermoplasma...    50   8e-05
UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter...    50   8e-05
UniRef50_Q18WQ6 Cluster: Malate dehydrogenase, NAD-dependent; n=...    49   1e-04
UniRef50_A2SNY0 Cluster: Malate/lactate dehydrogenases-like prot...    49   1e-04
UniRef50_Q3J7E7 Cluster: Malate dehydrogenase; n=5; Gammaproteob...    49   1e-04
UniRef50_A2Q223 Cluster: Lactate/malate dehydrogenase, alpha/bet...    49   1e-04
UniRef50_Q7M9A7 Cluster: Malate dehydrogenase; n=4; Epsilonprote...    49   1e-04
UniRef50_Q8TWG5 Cluster: Malate dehydrogenase; n=2; Euryarchaeot...    49   1e-04
UniRef50_A7DRG3 Cluster: Lactate/malate dehydrogenase; n=1; Cand...    48   2e-04
UniRef50_UPI0000D55CD8 Cluster: PREDICTED: similar to Malate DeH...    48   3e-04
UniRef50_A0RXX8 Cluster: Malate/L-lactate dehydrogenase; n=1; Ce...    48   3e-04
UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|R...    48   3e-04
UniRef50_P59390 Cluster: L-lactate dehydrogenase 2; n=8; Lactoba...    47   4e-04
UniRef50_Q81K80 Cluster: L-lactate dehydrogenase 2; n=12; Firmic...    47   4e-04
UniRef50_UPI0000DB6C4F Cluster: PREDICTED: similar to Malate DeH...    46   8e-04
UniRef50_Q07841 Cluster: Malate dehydrogenase; n=7; Halobacteria...    46   0.001
UniRef50_A7GYI6 Cluster: Lactate/malate dehydrogenase, NAD bindi...    45   0.002
UniRef50_P16115 Cluster: L-lactate dehydrogenase; n=4; Thermotog...    45   0.002
UniRef50_P0C0J4 Cluster: L-lactate dehydrogenase; n=5; Mycoplasm...    45   0.002
UniRef50_Q017A7 Cluster: Chromosome 06 contig 1, DNA sequence; n...    44   0.003
UniRef50_Q892U0 Cluster: L-lactate dehydrogenase; n=12; Bacteria...    44   0.004
UniRef50_A5Z9B1 Cluster: Putative uncharacterized protein; n=1; ...    44   0.005
UniRef50_Q27743 Cluster: L-lactate dehydrogenase; n=17; Apicompl...    44   0.005
UniRef50_A3EWH3 Cluster: Malate/lactate dehydrogenase; n=1; Lept...    43   0.007
UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex ae...    43   0.010
UniRef50_A0RPE9 Cluster: Malate dehydrogenase; n=1; Campylobacte...    42   0.013
UniRef50_Q7NHJ3 Cluster: Malate dehydrogenase; n=13; cellular or...    42   0.017
UniRef50_UPI0000D56DC5 Cluster: PREDICTED: similar to Malate deh...    42   0.022
UniRef50_Q7MTK2 Cluster: Malate dehydrogenase; n=4; Bacteroidale...    42   0.022
UniRef50_Q8I8U4 Cluster: Lactate dehydrogenase; n=3; Eimeriorina...    42   0.022
UniRef50_UPI00015B5ACF Cluster: PREDICTED: similar to ENSANGP000...    41   0.029
UniRef50_P0A3M9 Cluster: L-lactate dehydrogenase; n=140; Bacteri...    41   0.029
UniRef50_Q838C9 Cluster: L-lactate dehydrogenase 2; n=9; Bacilli...    41   0.029
UniRef50_Q23CW4 Cluster: Malate dehydrogenase, cytoplasmic, puta...    41   0.039
UniRef50_Q98PG4 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm...    41   0.039
UniRef50_Q6KIP9 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm...    41   0.039
UniRef50_Q8XP62 Cluster: L-lactate dehydrogenase; n=11; Clostrid...    41   0.039
UniRef50_O51114 Cluster: L-lactate dehydrogenase; n=4; Borrelia ...    40   0.051
UniRef50_A4BB89 Cluster: Lactate dehydrogenase; n=2; Gammaproteo...    40   0.068
UniRef50_A3DCA4 Cluster: L-lactate dehydrogenase precursor; n=2;...    40   0.068
UniRef50_Q3ZZJ7 Cluster: Malate dehydrogenase; n=5; cellular org...    40   0.068
UniRef50_Q9GPV2 Cluster: Cytosolic malate dehydrogenase; n=4; Tr...    40   0.089
UniRef50_Q6JH30 Cluster: Lactate dehydrogenase; n=3; Plasmodium ...    40   0.089
UniRef50_A0D8T3 Cluster: Malate dehydrogenase; n=2; Paramecium t...    40   0.089
UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;...    40   0.089
UniRef50_O26290 Cluster: Malate dehydrogenase; n=2; Methanobacte...    40   0.089
UniRef50_Q1FID3 Cluster: L-lactate dehydrogenase precursor; n=1;...    39   0.12 
UniRef50_A3CTN0 Cluster: Lactate/malate dehydrogenase; n=1; Meth...    39   0.12 
UniRef50_P62056 Cluster: L-lactate dehydrogenase; n=2; Bacteria|...    39   0.12 
UniRef50_Q6F0L9 Cluster: L-lactate dehydrogenase; n=6; Mollicute...    39   0.16 
UniRef50_P62051 Cluster: L-lactate dehydrogenase; n=2; Desulfovi...    38   0.27 
UniRef50_Q03BE6 Cluster: L-lactate dehydrogenase; n=1; Lactobaci...    38   0.36 
UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2; ...    37   0.63 
UniRef50_P61973 Cluster: Malate dehydrogenase; n=43; Bacteria|Re...    36   0.83 
UniRef50_Q81XJ7 Cluster: L-lactate dehydrogenase 3; n=13; Firmic...    36   0.83 
UniRef50_Q608X6 Cluster: Hydrophobe/amphiphile Efflux-1 (HAE1) f...    36   1.1  
UniRef50_A4A2L6 Cluster: L-lactate dehydrogenase; n=4; Bacteria|...    36   1.1  
UniRef50_A3JXA9 Cluster: L-lactate dehydrogenase; n=1; Sagittula...    36   1.1  
UniRef50_A2SSY4 Cluster: L-lactate dehydrogenase; n=3; Methanomi...    35   1.9  
UniRef50_P19869 Cluster: L-lactate dehydrogenase 2; n=17; Bacter...    35   1.9  
UniRef50_A1HSK3 Cluster: Lactate/malate dehydrogenase; n=1; Ther...    35   2.5  
UniRef50_A1W9K7 Cluster: Malate dehydrogenase; n=95; cellular or...    35   2.5  
UniRef50_O61865 Cluster: Putative uncharacterized protein; n=9; ...    34   3.4  
UniRef50_Q7UY63 Cluster: L-lactate/malate dehydrogenase; n=2; Pl...    34   4.4  
UniRef50_Q4QAY8 Cluster: Putative uncharacterized protein; n=3; ...    33   5.9  
UniRef50_A2E124 Cluster: Malate dehydrogenase; n=6; Trichomonadi...    33   5.9  
UniRef50_A2R2H9 Cluster: Similarity: the similarities are due to...    33   5.9  
UniRef50_UPI000023EEAF Cluster: hypothetical protein FG02077.1; ...    33   7.8  
UniRef50_Q0UU66 Cluster: Predicted protein; n=1; Phaeosphaeria n...    33   7.8  

>UniRef50_P08249 Cluster: Malate dehydrogenase, mitochondrial
           precursor; n=514; cellular organisms|Rep: Malate
           dehydrogenase, mitochondrial precursor - Mus musculus
           (Mouse)
          Length = 338

 Score =  115 bits (277), Expect = 1e-24
 Identities = 57/89 (64%), Positives = 68/89 (76%)
 Frame = +1

Query: 256 LVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPG 435
           LV+RL LYDIA  TPGVAADLSH+ T A V G+ GPE+L   +K  DVVVIPAGVPRKPG
Sbjct: 49  LVSRLTLYDIAH-TPGVAADLSHIETRANVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPG 107

Query: 436 MNRDDLFNTNASIVRDIALSIAQNDPKLL 522
           M RDDLFNTNA+IV  +  + AQ+ P+ +
Sbjct: 108 MTRDDLFNTNATIVATLTAACAQHCPEAM 136



 Score = 69.3 bits (162), Expect = 1e-10
 Identities = 29/43 (67%), Positives = 37/43 (86%)
 Frame = +3

Query: 510 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVV 638
           P+A+V II NPVNST+PI +EV KK GVY+PN++ GVTTLD+V
Sbjct: 133 PEAMVCIIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIV 175



 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 24/36 (66%), Positives = 29/36 (80%)
 Frame = +2

Query: 647 TFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQP 754
           TFV E+ G+DP  V VPVIGGH+G TIIP++SQC P
Sbjct: 179 TFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTP 214



 Score = 35.9 bits (79), Expect = 1.1
 Identities = 20/50 (40%), Positives = 29/50 (58%)
 Frame = +2

Query: 104 MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQN 253
           M S   +PA  A++   ++FST++Q N K         IGQPL+LLLK +
Sbjct: 1   MLSALARPAGAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNS 47


>UniRef50_P40926 Cluster: Malate dehydrogenase, mitochondrial
           precursor; n=119; cellular organisms|Rep: Malate
           dehydrogenase, mitochondrial precursor - Homo sapiens
           (Human)
          Length = 338

 Score =  115 bits (277), Expect = 1e-24
 Identities = 57/89 (64%), Positives = 68/89 (76%)
 Frame = +1

Query: 256 LVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPG 435
           LV+RL LYDIA  TPGVAADLSH+ T A V G+ GPE+L   +K  DVVVIPAGVPRKPG
Sbjct: 49  LVSRLTLYDIAH-TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPG 107

Query: 436 MNRDDLFNTNASIVRDIALSIAQNDPKLL 522
           M RDDLFNTNA+IV  +  + AQ+ P+ +
Sbjct: 108 MTRDDLFNTNATIVATLTAACAQHCPEAM 136



 Score = 68.5 bits (160), Expect = 2e-10
 Identities = 27/43 (62%), Positives = 37/43 (86%)
 Frame = +3

Query: 510 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVV 638
           P+A++ +I NPVNST+PI +EV KK GVY+PN++ GVTTLD+V
Sbjct: 133 PEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIV 175



 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 24/36 (66%), Positives = 29/36 (80%)
 Frame = +2

Query: 647 TFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQP 754
           TFV E+ G+DP  V VPVIGGH+G TIIP++SQC P
Sbjct: 179 TFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTP 214



 Score = 34.7 bits (76), Expect = 2.5
 Identities = 19/50 (38%), Positives = 29/50 (58%)
 Frame = +2

Query: 104 MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQN 253
           M S   +P + A++   ++FST++Q N K         IGQPL+LLLK +
Sbjct: 1   MLSALARPVSAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNS 47


>UniRef50_Q9SN86 Cluster: Malate dehydrogenase, chloroplast
           precursor; n=41; cellular organisms|Rep: Malate
           dehydrogenase, chloroplast precursor - Arabidopsis
           thaliana (Mouse-ear cress)
          Length = 403

 Score =  109 bits (262), Expect = 7e-23
 Identities = 54/86 (62%), Positives = 66/86 (76%)
 Frame = +1

Query: 256 LVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPG 435
           LV+ L LYDIA V  GVAADLSH NTP++V    GP EL+  +KD +VVVIPAGVPRKPG
Sbjct: 107 LVSTLHLYDIANVK-GVAADLSHCNTPSQVRDFTGPSELADCLKDVNVVVIPAGVPRKPG 165

Query: 436 MNRDDLFNTNASIVRDIALSIAQNDP 513
           M RDDLFN NA+IV+ +  ++A+N P
Sbjct: 166 MTRDDLFNINANIVKTLVEAVAENCP 191



 Score = 70.9 bits (166), Expect = 3e-11
 Identities = 32/43 (74%), Positives = 37/43 (86%)
 Frame = +3

Query: 510 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVV 638
           P A + II+NPVNSTVPIA+EVLKK GVYDP ++ GVTTLDVV
Sbjct: 191 PNAFIHIISNPVNSTVPIAAEVLKKKGVYDPKKLFGVTTLDVV 233



 Score = 44.4 bits (100), Expect = 0.003
 Identities = 19/38 (50%), Positives = 28/38 (73%)
 Frame = +2

Query: 647 TFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQPAL 760
           TFV +   +    V VPVIGGH+GITI+P+LS+ +P++
Sbjct: 237 TFVSQKKNLKLIDVDVPVIGGHAGITILPLLSKTKPSV 274


>UniRef50_A3BMG8 Cluster: Putative uncharacterized protein; n=3;
           Oryza sativa|Rep: Putative uncharacterized protein -
           Oryza sativa subsp. japonica (Rice)
          Length = 405

 Score =  106 bits (254), Expect = 7e-22
 Identities = 53/86 (61%), Positives = 62/86 (72%)
 Frame = +1

Query: 256 LVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPG 435
           LV+ L LYDIA V  GV ADL H NTPAKV+G  G EEL+  +   DVVVIPAGVPRKPG
Sbjct: 102 LVSALHLYDIANVD-GVTADLGHCNTPAKVAGFTGKEELAGCLAGVDVVVIPAGVPRKPG 160

Query: 436 MNRDDLFNTNASIVRDIALSIAQNDP 513
           M RDDLF  NA IVR++  ++A + P
Sbjct: 161 MTRDDLFGINAGIVRELVEAVADHAP 186


>UniRef50_A2QMH9 Cluster: Malate dehydrogenase; n=7; Fungi/Metazoa
           group|Rep: Malate dehydrogenase - Aspergillus niger
          Length = 340

 Score =  104 bits (250), Expect = 2e-21
 Identities = 53/88 (60%), Positives = 68/88 (77%), Gaps = 1/88 (1%)
 Frame = +1

Query: 256 LVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKG-PEELSAAIKDADVVVIPAGVPRKP 432
           LVT LALYDI    PGVAAD+SH+NT + V G++  P  L  A+K +++++IPAGVPRKP
Sbjct: 48  LVTDLALYDIRG-GPGVAADISHINTNSTVKGYEPTPSGLRDALKGSEIILIPAGVPRKP 106

Query: 433 GMNRDDLFNTNASIVRDIALSIAQNDPK 516
           GM RDDLFNTNASIVRD+A + A+  P+
Sbjct: 107 GMTRDDLFNTNASIVRDLAKAAAEAAPE 134



 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 29/43 (67%), Positives = 35/43 (81%)
 Frame = +3

Query: 510 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVV 638
           P+A + +I+NPVNSTVPI SEV K  GVY+P R+ GVTTLDVV
Sbjct: 133 PEANILVISNPVNSTVPIVSEVYKSKGVYNPKRLFGVTTLDVV 175



 Score = 48.0 bits (109), Expect = 3e-04
 Identities = 18/32 (56%), Positives = 26/32 (81%)
 Frame = +2

Query: 650 FVGEINGVDPTSVAVPVIGGHSGITIIPILSQ 745
           F+ ++ G +P + AV VIGGHSG+TI+P+LSQ
Sbjct: 180 FISQVKGTNPANEAVTVIGGHSGVTIVPLLSQ 211


>UniRef50_A7SQS1 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 254

 Score =  103 bits (246), Expect = 6e-21
 Identities = 46/74 (62%), Positives = 62/74 (83%)
 Frame = +1

Query: 301 GVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMNRDDLFNTNASIVR 480
           GVAADLSH++T AKV+ H+GP++L AA++   VV IPAGVPRKPGM RDDLFNTNASIV+
Sbjct: 7   GVAADLSHISTRAKVTSHQGPDDLKAALEGCSVVAIPAGVPRKPGMTRDDLFNTNASIVK 66

Query: 481 DIALSIAQNDPKLL 522
           +++ + A++ PK +
Sbjct: 67  NLSEACAKHCPKAI 80



 Score = 79.0 bits (186), Expect = 1e-13
 Identities = 36/43 (83%), Positives = 40/43 (93%)
 Frame = +3

Query: 510 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVV 638
           PKAI+ II+NPVNSTVPIASEV KKAGVYDP R+LGVTTLD+V
Sbjct: 77  PKAIICIISNPVNSTVPIASEVYKKAGVYDPARILGVTTLDIV 119


>UniRef50_Q9Y7R8 Cluster: Malate dehydrogenase; n=13; Dikarya|Rep:
           Malate dehydrogenase - Schizosaccharomyces pombe
           (Fission yeast)
          Length = 341

 Score = 97.5 bits (232), Expect = 3e-19
 Identities = 49/87 (56%), Positives = 63/87 (72%), Gaps = 1/87 (1%)
 Frame = +1

Query: 259 VTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEE-LSAAIKDADVVVIPAGVPRKPG 435
           V+ LAL+DI    PGVAAD+ H+NT + V G+   ++ L  A+  ADVV+IPAGVPRKPG
Sbjct: 54  VSELALFDIRGA-PGVAADIGHINTTSNVVGYAPDDKGLEKALNGADVVIIPAGVPRKPG 112

Query: 436 MNRDDLFNTNASIVRDIALSIAQNDPK 516
           M RDDLF TNASIVRD+A +  +  P+
Sbjct: 113 MTRDDLFATNASIVRDLAFAAGETCPE 139



 Score = 53.6 bits (123), Expect = 5e-06
 Identities = 23/43 (53%), Positives = 31/43 (72%)
 Frame = +3

Query: 510 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVV 638
           P+A   ++TNPVNSTVPI  + L++ GV+ P  + GVTTLD V
Sbjct: 138 PEAKYLVVTNPVNSTVPIFKKALERVGVHQPKHLFGVTTLDSV 180



 Score = 37.1 bits (82), Expect = 0.48
 Identities = 14/32 (43%), Positives = 21/32 (65%)
 Frame = +2

Query: 650 FVGEINGVDPTSVAVPVIGGHSGITIIPILSQ 745
           F  ++       + +PV+GGHSG TI+P+LSQ
Sbjct: 185 FTSQVTNGKAELLHIPVVGGHSGATIVPLLSQ 216



 Score = 35.5 bits (78), Expect = 1.5
 Identities = 17/33 (51%), Positives = 21/33 (63%)
 Frame = +2

Query: 155 KNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQN 253
           ++FSTTS R FK         IGQPL++LLK N
Sbjct: 19  RSFSTTSSRAFKVAVLGAGGGIGQPLSMLLKLN 51


>UniRef50_Q42972 Cluster: Malate dehydrogenase, glyoxysomal
           precursor; n=11; Eukaryota|Rep: Malate dehydrogenase,
           glyoxysomal precursor - Oryza sativa subsp. japonica
           (Rice)
          Length = 356

 Score = 97.5 bits (232), Expect = 3e-19
 Identities = 50/89 (56%), Positives = 60/89 (67%)
 Frame = +1

Query: 256 LVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPG 435
           LV+ L LYD+   TPGV AD+SHMNT A V G  G  +L  A+   D+V+IPAGVPRKPG
Sbjct: 69  LVSVLHLYDVVN-TPGVTADISHMNTGAVVRGFLGQPQLENALTGMDLVIIPAGVPRKPG 127

Query: 436 MNRDDLFNTNASIVRDIALSIAQNDPKLL 522
           M RDDLFN NA IVR +   IA+  P  +
Sbjct: 128 MTRDDLFNINAGIVRTLCEGIAKCCPNAI 156



 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 34/43 (79%), Positives = 38/43 (88%)
 Frame = +3

Query: 510 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVV 638
           P AIV +I+NPVNSTVPIA+EV KKAG YDP R+LGVTTLDVV
Sbjct: 153 PNAIVNVISNPVNSTVPIAAEVFKKAGTYDPKRLLGVTTLDVV 195



 Score = 56.0 bits (129), Expect = 1e-06
 Identities = 23/36 (63%), Positives = 29/36 (80%)
 Frame = +2

Query: 647 TFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQP 754
           TFV E+ G+DP  V VPVIGGH+G+TI+P+LSQ  P
Sbjct: 199 TFVAEVLGLDPRDVNVPVIGGHAGVTILPLLSQVNP 234


>UniRef50_Q75AT4 Cluster: ADL164Cp; n=2; Saccharomycetales|Rep:
           ADL164Cp - Ashbya gossypii (Yeast) (Eremothecium
           gossypii)
          Length = 381

 Score = 90.2 bits (214), Expect = 5e-17
 Identities = 49/84 (58%), Positives = 57/84 (67%), Gaps = 6/84 (7%)
 Frame = +1

Query: 268 LALYDIAP-VTPGVAADLSHMNTPAKVSGH-----KGPEELSAAIKDADVVVIPAGVPRK 429
           LALYD+A     GVAADLSH+NTP +VS H     +  E L  A+  A VVVIPAGVPRK
Sbjct: 60  LALYDVAADALAGVAADLSHVNTPVEVSHHVPSSREDEEALREALTGASVVVIPAGVPRK 119

Query: 430 PGMNRDDLFNTNASIVRDIALSIA 501
           PGM RDDL N NA I++ +A  IA
Sbjct: 120 PGMTRDDLININAGIIKTLAKGIA 143



 Score = 35.5 bits (78), Expect = 1.5
 Identities = 18/37 (48%), Positives = 23/37 (62%)
 Frame = +2

Query: 653 VGEINGVDPTSVAVPVIGGHSGITIIPILSQCQPALQ 763
           +GE+    P+   VPVIGGHSG TI+P+    Q  LQ
Sbjct: 207 LGELGNEVPS---VPVIGGHSGETILPLFGPVQQRLQ 240


>UniRef50_Q6BM17 Cluster: Malate dehydrogenase; n=4; Eukaryota|Rep:
           Malate dehydrogenase - Debaryomyces hansenii (Yeast)
           (Torulaspora hansenii)
          Length = 346

 Score = 88.6 bits (210), Expect = 1e-16
 Identities = 47/90 (52%), Positives = 64/90 (71%), Gaps = 5/90 (5%)
 Frame = +1

Query: 259 VTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEE-----LSAAIKDADVVVIPAGVP 423
           V+ L+L+D+     GVAADLSH+ +PAKV+G++   +     +  A+ ++D+VVIPAGVP
Sbjct: 27  VSELSLFDVVNAN-GVAADLSHICSPAKVTGYQPSSKEDRDTIQKALVNSDLVVIPAGVP 85

Query: 424 RKPGMNRDDLFNTNASIVRDIALSIAQNDP 513
           RKPGM R DLFN NASI+RDI  SI +  P
Sbjct: 86  RKPGMTRADLFNINASIIRDIVGSIGKACP 115



 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 29/43 (67%), Positives = 36/43 (83%)
 Frame = +3

Query: 510 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVV 638
           P A + II+NPVNSTVPIA+EVLKK GV++P ++ GVTTLD V
Sbjct: 115 PNAAILIISNPVNSTVPIAAEVLKKLGVFNPKKLFGVTTLDSV 157



 Score = 35.9 bits (79), Expect = 1.1
 Identities = 17/33 (51%), Positives = 24/33 (72%), Gaps = 2/33 (6%)
 Frame = +2

Query: 647 TFVGEINGVDPTSVA--VPVIGGHSGITIIPIL 739
           TF+GE+    PTS+   + VIGGHSG TI+P++
Sbjct: 161 TFLGELIKETPTSLKGQISVIGGHSGDTIVPLV 193


>UniRef50_Q6FL22 Cluster: Malate dehydrogenase; n=1; Candida
           glabrata|Rep: Malate dehydrogenase - Candida glabrata
           (Yeast) (Torulopsis glabrata)
          Length = 373

 Score = 88.2 bits (209), Expect = 2e-16
 Identities = 43/87 (49%), Positives = 63/87 (72%)
 Frame = +1

Query: 253 SLVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKP 432
           ++++ LALYDI  +  GVA DLSH+NT A   G+   +++  A+K A VVVIPAGVPR+P
Sbjct: 25  TMISELALYDIK-LAEGVATDLSHINTNADCVGYS-TDDIGQALKGAAVVVIPAGVPRRP 82

Query: 433 GMNRDDLFNTNASIVRDIALSIAQNDP 513
           G+ RDDLF  NA IV+++  ++A++ P
Sbjct: 83  GITRDDLFKLNAGIVKNLVSNVAKHCP 109



 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 24/43 (55%), Positives = 32/43 (74%)
 Frame = +3

Query: 510 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVV 638
           P A + II+NPVNS +P+A E LK+ GV+    V+GVTTLD+V
Sbjct: 109 PNARLLIISNPVNSLIPVAVETLKRCGVFQAGNVMGVTTLDLV 151


>UniRef50_A7TL95 Cluster: Putative uncharacterized protein; n=1;
           Vanderwaltozyma polyspora DSM 70294|Rep: Putative
           uncharacterized protein - Vanderwaltozyma polyspora DSM
           70294
          Length = 365

 Score = 87.8 bits (208), Expect = 3e-16
 Identities = 38/85 (44%), Positives = 59/85 (69%)
 Frame = +1

Query: 259 VTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGM 438
           V+ LALYDI+ +T GVA DLSH+NT +   G+   E+    ++ +++V++ AG+PRKPGM
Sbjct: 27  VSDLALYDISDITAGVAKDLSHINTNSDSEGYNKDEDFKNLLEGSELVIVTAGIPRKPGM 86

Query: 439 NRDDLFNTNASIVRDIALSIAQNDP 513
            RDDLF  NA I++++ +  A+  P
Sbjct: 87  TRDDLFKINAKIIQNLTVKYAKFAP 111



 Score = 44.4 bits (100), Expect = 0.003
 Identities = 18/37 (48%), Positives = 27/37 (72%)
 Frame = +3

Query: 528 IITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVV 638
           II+NPVNS +P+  E LK  G  +P++V G+T LD++
Sbjct: 118 IISNPVNSLIPVVIETLKINGRLNPSQVFGITMLDII 154


>UniRef50_P22133 Cluster: Malate dehydrogenase, cytoplasmic; n=3;
           Saccharomycetaceae|Rep: Malate dehydrogenase,
           cytoplasmic - Saccharomyces cerevisiae (Baker's yeast)
          Length = 377

 Score = 87.8 bits (208), Expect = 3e-16
 Identities = 43/80 (53%), Positives = 53/80 (66%), Gaps = 1/80 (1%)
 Frame = +1

Query: 268 LALYDI-APVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMNR 444
           LALYD+      GV ADLSH++TP  VS H     +   + +A +VVIPAGVPRKPGM R
Sbjct: 53  LALYDVNQEAINGVTADLSHIDTPISVSSHSPAGGIENCLHNASIVVIPAGVPRKPGMTR 112

Query: 445 DDLFNTNASIVRDIALSIAQ 504
           DDLFN NA I+  +  SIA+
Sbjct: 113 DDLFNVNAGIISQLGDSIAE 132



 Score = 36.7 bits (81), Expect = 0.63
 Identities = 22/39 (56%), Positives = 26/39 (66%), Gaps = 6/39 (15%)
 Frame = +2

Query: 647 TFVGEIN---GVDP---TSVAVPVIGGHSGITIIPILSQ 745
           TF+ EIN   G+ P   +   VPVIGGHSG TIIP+ SQ
Sbjct: 188 TFLREINIESGLTPRVNSMPDVPVIGGHSGETIIPLFSQ 226



 Score = 35.1 bits (77), Expect = 1.9
 Identities = 21/49 (42%), Positives = 30/49 (61%), Gaps = 7/49 (14%)
 Frame = +3

Query: 513 KAIVAIITNPVNSTVPI-ASEVLK------KAGVYDPNRVLGVTTLDVV 638
           K  V +I+NPVNS VP+  S +LK       +G+    R++GVT LD+V
Sbjct: 138 KVFVLVISNPVNSLVPVMVSNILKNHPQSRNSGI--ERRIMGVTKLDIV 184


>UniRef50_Q9VU29 Cluster: Malate dehydrogenase; n=5;
           Protostomia|Rep: Malate dehydrogenase - Drosophila
           melanogaster (Fruit fly)
          Length = 347

 Score = 83.8 bits (198), Expect = 4e-15
 Identities = 41/85 (48%), Positives = 57/85 (67%)
 Frame = +1

Query: 259 VTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGM 438
           ++ L+LYDI   T GV  DLSH+NT A V   +G   L  A+  AD+VVIPAG+PRKPGM
Sbjct: 53  ISTLSLYDIKNTT-GVGVDLSHINTRASVCPFEGKNGLKKAMDKADIVVIPAGLPRKPGM 111

Query: 439 NRDDLFNTNASIVRDIALSIAQNDP 513
            R+DL + NAS+  ++A + ++  P
Sbjct: 112 KREDLVDVNASVACEVAFAASEVCP 136



 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 27/43 (62%), Positives = 33/43 (76%)
 Frame = +3

Query: 510 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVV 638
           P A++A ITNP+N  VPI + +LK  G YDPNR+ GVTTLDVV
Sbjct: 136 PGAMLAFITNPINVIVPIVATILKAKGTYDPNRLFGVTTLDVV 178



 Score = 56.0 bits (129), Expect = 1e-06
 Identities = 24/36 (66%), Positives = 28/36 (77%)
 Frame = +2

Query: 647 TFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQP 754
           TFV +I  VDP  V +PVIGGH+G TI+PILSQC P
Sbjct: 182 TFVADILNVDPQKVNIPVIGGHTGRTILPILSQCDP 217


>UniRef50_A7TSF5 Cluster: Putative uncharacterized protein; n=1;
           Vanderwaltozyma polyspora DSM 70294|Rep: Putative
           uncharacterized protein - Vanderwaltozyma polyspora DSM
           70294
          Length = 387

 Score = 81.4 bits (192), Expect = 2e-14
 Identities = 42/75 (56%), Positives = 55/75 (73%), Gaps = 1/75 (1%)
 Frame = +1

Query: 268 LALYDI-APVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMNR 444
           LAL+D+   V  GV ADLSH+NT  K+S H   + L  ++ D+++V+IPAGVPRKPGM R
Sbjct: 74  LALFDVNMKVLNGVHADLSHVNTNMKLSLH---DNLRDSLVDSNLVIIPAGVPRKPGMTR 130

Query: 445 DDLFNTNASIVRDIA 489
           DDLFN NA I++ IA
Sbjct: 131 DDLFNINAGIIKGIA 145



 Score = 37.9 bits (84), Expect = 0.27
 Identities = 15/19 (78%), Positives = 17/19 (89%)
 Frame = +2

Query: 692 VPVIGGHSGITIIPILSQC 748
           VPVIGGHSG TI+P+LS C
Sbjct: 215 VPVIGGHSGDTILPVLSNC 233


>UniRef50_Q4Q3J3 Cluster: Malate dehydrogenase, putative; n=3;
           Leishmania|Rep: Malate dehydrogenase, putative -
           Leishmania major
          Length = 331

 Score = 77.8 bits (183), Expect = 3e-13
 Identities = 42/87 (48%), Positives = 59/87 (67%), Gaps = 1/87 (1%)
 Frame = +1

Query: 259 VTRLALYDIAPVTP-GVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPG 435
           V+ LALYDI  V P GVA DLSH     KV+G+   + +  A+  AD+V++ AG+PR+PG
Sbjct: 34  VSELALYDI--VQPRGVAVDLSHFPRKVKVTGYP-TKWIHKALDGADLVLMSAGMPRRPG 90

Query: 436 MNRDDLFNTNASIVRDIALSIAQNDPK 516
           M  DDLFNTNA  V +++ ++A+  PK
Sbjct: 91  MTHDDLFNTNALTVNELSAAVARYAPK 117



 Score = 59.3 bits (137), Expect = 1e-07
 Identities = 22/43 (51%), Positives = 38/43 (88%)
 Frame = +3

Query: 510 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVV 638
           PK+++AII+NP+NS VP+A+E L++AGVYDP ++ G+ +L+++
Sbjct: 116 PKSVLAIISNPLNSMVPVAAETLQRAGVYDPRKLFGIISLNMM 158



 Score = 41.9 bits (94), Expect = 0.017
 Identities = 17/30 (56%), Positives = 22/30 (73%)
 Frame = +2

Query: 653 VGEINGVDPTSVAVPVIGGHSGITIIPILS 742
           +G+  G DP  + VPVIGGHSG TI+P+ S
Sbjct: 164 LGDFTGQDPEMLDVPVIGGHSGQTIVPLFS 193


>UniRef50_P32419 Cluster: Malate dehydrogenase, peroxisomal; n=24;
           Eukaryota|Rep: Malate dehydrogenase, peroxisomal -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 343

 Score = 77.8 bits (183), Expect = 3e-13
 Identities = 38/85 (44%), Positives = 54/85 (63%)
 Frame = +1

Query: 259 VTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGM 438
           V+ LALYDI     G+  DLSH+NT +   G+   + +   + +A VV+IPAGVPRKPG+
Sbjct: 27  VSELALYDIR-AAEGIGKDLSHINTNSSCVGYD-KDSIENTLSNAQVVLIPAGVPRKPGL 84

Query: 439 NRDDLFNTNASIVRDIALSIAQNDP 513
            RDDLF  NA IV+ +  ++ +  P
Sbjct: 85  TRDDLFKMNAGIVKSLVTAVGKFAP 109



 Score = 55.6 bits (128), Expect = 1e-06
 Identities = 25/43 (58%), Positives = 31/43 (72%)
 Frame = +3

Query: 510 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVV 638
           P A + +I+NPVNS VPIA E LKK G + P  V+GVT LD+V
Sbjct: 109 PNARILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLV 151


>UniRef50_Q9VU28 Cluster: Malate dehydrogenase; n=3; Sophophora|Rep:
           Malate dehydrogenase - Drosophila melanogaster (Fruit
           fly)
          Length = 349

 Score = 77.0 bits (181), Expect = 5e-13
 Identities = 36/86 (41%), Positives = 55/86 (63%)
 Frame = +1

Query: 259 VTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGM 438
           +  LAL+D++ +  G+A DLSH++   KV G  G +EL +A+  ADVVV+ AG+PR PGM
Sbjct: 48  IDELALHDLSEMK-GIATDLSHISQTGKVIGFTGEKELESAVSGADVVVVAAGMPRLPGM 106

Query: 439 NRDDLFNTNASIVRDIALSIAQNDPK 516
            RD L   N ++   +A +I+   P+
Sbjct: 107 QRDHLMAANGNVAVKVATAISNASPR 132



 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 25/43 (58%), Positives = 31/43 (72%)
 Frame = +3

Query: 510 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVV 638
           P+A +A ITNPVN  VP A+EVL   G +D  R+ G+TTLDVV
Sbjct: 131 PRAHLAFITNPVNMIVPAAAEVLMAHGTFDSRRLFGITTLDVV 173



 Score = 54.4 bits (125), Expect = 3e-06
 Identities = 20/35 (57%), Positives = 28/35 (80%)
 Frame = +2

Query: 650 FVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQP 754
           F+G+   + P  V +PVIGGH+GITI+P++SQCQP
Sbjct: 178 FIGDSMNISPDDVNIPVIGGHAGITILPLISQCQP 212


>UniRef50_Q6CP51 Cluster: Similar to sp|P22133 Saccharomyces
           cerevisiae YOL126c MDH2 malate dehydrogenase; n=1;
           Kluyveromyces lactis|Rep: Similar to sp|P22133
           Saccharomyces cerevisiae YOL126c MDH2 malate
           dehydrogenase - Kluyveromyces lactis (Yeast) (Candida
           sphaerica)
          Length = 404

 Score = 77.0 bits (181), Expect = 5e-13
 Identities = 38/84 (45%), Positives = 53/84 (63%), Gaps = 4/84 (4%)
 Frame = +1

Query: 265 RLALYDI-APVTPGVAADLSHMNTPAKVSGHKGPEE---LSAAIKDADVVVIPAGVPRKP 432
           RL+LYD+      G AADLSH++TP   + H   +    +   + +A VV+IPAGVPRKP
Sbjct: 83  RLSLYDVNKDAIVGTAADLSHIDTPITTTAHYPDDSNGGIGQCLSNASVVIIPAGVPRKP 142

Query: 433 GMNRDDLFNTNASIVRDIALSIAQ 504
           GM+RDDL   NA I++ +   IA+
Sbjct: 143 GMSRDDLIGVNAKIIKSLGEDIAK 166



 Score = 41.9 bits (94), Expect = 0.017
 Identities = 20/33 (60%), Positives = 24/33 (72%), Gaps = 1/33 (3%)
 Frame = +2

Query: 647 TFVGEINGVDP-TSVAVPVIGGHSGITIIPILS 742
           TFV ++NG    TS  +PVIGGHSG TIIP+ S
Sbjct: 221 TFVQQLNGFKSNTSPVIPVIGGHSGDTIIPVFS 253


>UniRef50_Q86DP2 Cluster: Malate dehydrogenase; n=11; Fungi/Metazoa
           group|Rep: Malate dehydrogenase - Plicopurpura patula
          Length = 229

 Score = 76.2 bits (179), Expect = 8e-13
 Identities = 36/43 (83%), Positives = 38/43 (88%)
 Frame = +3

Query: 510 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVV 638
           P A++ IITNPVNSTVPIASEVLKK GVYDP RV GVTTLDVV
Sbjct: 22  PTAMLGIITNPVNSTVPIASEVLKKRGVYDPKRVFGVTTLDVV 64



 Score = 57.2 bits (132), Expect = 4e-07
 Identities = 23/36 (63%), Positives = 28/36 (77%)
 Frame = +2

Query: 647 TFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQP 754
           TF+ E  G+D T   VPVIGGHSG+TIIP++SQC P
Sbjct: 68  TFIAEAKGLDVTKTNVPVIGGHSGVTIIPLISQCTP 103


>UniRef50_Q4QDF0 Cluster: Glycosomal malate dehydrogenase; n=9;
           Trypanosomatidae|Rep: Glycosomal malate dehydrogenase -
           Leishmania major
          Length = 322

 Score = 75.8 bits (178), Expect = 1e-12
 Identities = 43/93 (46%), Positives = 56/93 (60%), Gaps = 7/93 (7%)
 Frame = +1

Query: 268 LALYDIAPVTPGVAADLSHM-NTPAKVS------GHKGPEELSAAIKDADVVVIPAGVPR 426
           L+L+D+     GVAADLSH+ N   +V       GHK    L+   K  DV V+ AGVPR
Sbjct: 31  LSLFDVVGAA-GVAADLSHVDNAGVQVKFAEGKIGHKRDPALAELAKGVDVFVMVAGVPR 89

Query: 427 KPGMNRDDLFNTNASIVRDIALSIAQNDPKLLW 525
           KPGM RDDLF  NA I+ D+ L+ A + PK ++
Sbjct: 90  KPGMTRDDLFKINAGIILDLVLTCASSSPKAVF 122



 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 28/41 (68%), Positives = 33/41 (80%)
 Frame = +3

Query: 510 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLD 632
           PKA+  I+TNPVNSTV IA+E LK  GVYD NR+LGV+ LD
Sbjct: 118 PKAVFCIVTNPVNSTVAIAAEALKSLGVYDRNRLLGVSLLD 158


>UniRef50_UPI00005A0834 Cluster: PREDICTED: similar to Malate
           dehydrogenase, mitochondrial precursor; n=1; Canis lupus
           familiaris|Rep: PREDICTED: similar to Malate
           dehydrogenase, mitochondrial precursor - Canis
           familiaris
          Length = 245

 Score = 67.7 bits (158), Expect = 3e-10
 Identities = 27/43 (62%), Positives = 37/43 (86%)
 Frame = +3

Query: 510 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVV 638
           P+A++ +I+NPVNST+PIA+EV KK G YDPN++  VTTLD+V
Sbjct: 91  PEAMICVISNPVNSTIPIATEVFKKHGAYDPNKIFRVTTLDIV 133



 Score = 46.0 bits (104), Expect = 0.001
 Identities = 20/34 (58%), Positives = 25/34 (73%)
 Frame = +1

Query: 421 PRKPGMNRDDLFNTNASIVRDIALSIAQNDPKLL 522
           PRKPGM RDDLFNTNAS+V     + AQ+ P+ +
Sbjct: 61  PRKPGMTRDDLFNTNASVVATPTAACAQHCPEAM 94


>UniRef50_Q017A6 Cluster: Malate dehydrogenase; n=2; cellular
           organisms|Rep: Malate dehydrogenase - Ostreococcus tauri
          Length = 477

 Score = 65.3 bits (152), Expect = 2e-09
 Identities = 29/43 (67%), Positives = 36/43 (83%)
 Frame = +3

Query: 510 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVV 638
           P A++ +I+NPVNSTVPIA+EVLK  G YDP ++ GVTTLDVV
Sbjct: 26  PNAMINMISNPVNSTVPIAAEVLKAKGKYDPKKLFGVTTLDVV 68



 Score = 46.4 bits (105), Expect = 8e-04
 Identities = 19/36 (52%), Positives = 26/36 (72%)
 Frame = +2

Query: 647 TFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQP 754
           TF  E  G++ + V VPV+GGH+GITI+P+ SQ  P
Sbjct: 72  TFYAEKAGLETSKVDVPVVGGHAGITILPLFSQATP 107


>UniRef50_Q6VVP7 Cluster: Malate dehydrogenase; n=6; Plasmodium|Rep:
           Malate dehydrogenase - Plasmodium falciparum
          Length = 313

 Score = 62.9 bits (146), Expect = 8e-09
 Identities = 34/78 (43%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
 Frame = +1

Query: 268 LALYDIAPVTP-GVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMNR 444
           L LYD+ P  P G A DL H +T   V+ +         IKDAD++VI AGV RK GM R
Sbjct: 28  LILYDVVPGIPQGKALDLKHFSTILGVNRNILGTNQIEDIKDADIIVITAGVQRKEGMTR 87

Query: 445 DDLFNTNASIVRDIALSI 498
           +DL   N  I++ +A S+
Sbjct: 88  EDLIGVNGKIMKSVAESV 105


>UniRef50_Q5ENS5 Cluster: Malate dehydrogenase; n=1; Heterocapsa
           triquetra|Rep: Malate dehydrogenase - Heterocapsa
           triquetra (Dinoflagellate)
          Length = 402

 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 36/94 (38%), Positives = 50/94 (53%), Gaps = 9/94 (9%)
 Frame = +1

Query: 259 VTRLALYDI-APVTP--GVAADLSHMNTPAKVSGH------KGPEELSAAIKDADVVVIP 411
           V  L ++D+   + P  GVA DL H+   A V G+      K  + L   +    +V+IP
Sbjct: 106 VKELCVFDLNVAMVPAQGVATDLGHLEKKAAVKGYVMEVGQKPVDNLEECLTGCHLVLIP 165

Query: 412 AGVPRKPGMNRDDLFNTNASIVRDIALSIAQNDP 513
           AG+PRKPG  RDDLF  NA I + I  + A+  P
Sbjct: 166 AGMPRKPGQTRDDLFKINADIAKGIVEACAKYCP 199



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 23/43 (53%), Positives = 33/43 (76%)
 Frame = +3

Query: 510 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVV 638
           P A++ +I NPVNS VP  +E+ KK G+ DP +++G+TTLDVV
Sbjct: 199 PDAMLGMIVNPVNSVVPAMAELYKKKGL-DPMKIVGITTLDVV 240



 Score = 36.7 bits (81), Expect = 0.63
 Identities = 15/23 (65%), Positives = 18/23 (78%)
 Frame = +2

Query: 677 PTSVAVPVIGGHSGITIIPILSQ 745
           P  V VPVIGGH+G TI+P+ SQ
Sbjct: 253 PDRVNVPVIGGHAGTTILPLFSQ 275


>UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular
           organisms|Rep: Malate dehydrogenase - Silicibacter
           pomeroyi
          Length = 320

 Score = 58.4 bits (135), Expect = 2e-07
 Identities = 31/83 (37%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
 Frame = +1

Query: 268 LALYDIAPVTP-GVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMNR 444
           + L+DIA  TP G A D++               +  A I  ADV ++ AGVPRKPGM+R
Sbjct: 30  VVLFDIAEGTPEGKALDIAESGPSEGFDAKLKGTQSYADIAGADVCIVTAGVPRKPGMSR 89

Query: 445 DDLFNTNASIVRDIALSIAQNDP 513
           DDL   N  +++ +   I  N P
Sbjct: 90  DDLLGINLKVMKSVGEGIRDNAP 112


>UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Rep:
           Malate dehydrogenase - Brucella melitensis
          Length = 320

 Score = 57.2 bits (132), Expect = 4e-07
 Identities = 31/84 (36%), Positives = 45/84 (53%), Gaps = 1/84 (1%)
 Frame = +1

Query: 268 LALYDIAPVTP-GVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMNR 444
           + L+DIA  TP G   D++  +               AAI+ ADVV++ AGVPRKPGM+R
Sbjct: 30  VVLFDIAEGTPQGKGLDIAESSPVDGFDAKFTGANDYAAIEGADVVIVTAGVPRKPGMSR 89

Query: 445 DDLFNTNASIVRDIALSIAQNDPK 516
           DDL   N  ++  +   I +  P+
Sbjct: 90  DDLLGINLKVMEQVGAGIKKYAPE 113


>UniRef50_O08349 Cluster: Malate dehydrogenase; n=1; Archaeoglobus
           fulgidus|Rep: Malate dehydrogenase - Archaeoglobus
           fulgidus
          Length = 294

 Score = 57.2 bits (132), Expect = 4e-07
 Identities = 36/91 (39%), Positives = 53/91 (58%), Gaps = 5/91 (5%)
 Frame = +1

Query: 259 VTRLALYDIAP-VTPGVAADLSHMNTPAKVSGHKGPEELSAA----IKDADVVVIPAGVP 423
           V  +AL DIA  +  G A DL+H    A     K P+ +  A    +K ++++V+ AG+ 
Sbjct: 25  VDEIALVDIAEDLAVGEAMDLAH----AAAGIDKYPKIVGGADYSLLKGSEIIVVTAGLA 80

Query: 424 RKPGMNRDDLFNTNASIVRDIALSIAQNDPK 516
           RKPGM R DL + NA I++DIA  I +N P+
Sbjct: 81  RKPGMTRLDLAHKNAGIIKDIAKKIVENAPE 111


>UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3;
           Actinomycetales|Rep: Lactate/malate dehydrogenase -
           Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
          Length = 330

 Score = 56.8 bits (131), Expect = 6e-07
 Identities = 27/44 (61%), Positives = 33/44 (75%)
 Frame = +1

Query: 382 IKDADVVVIPAGVPRKPGMNRDDLFNTNASIVRDIALSIAQNDP 513
           I DA +V+I AGVPRKPGM+R DL  TNA IVR +A +IA+  P
Sbjct: 85  IADASIVIITAGVPRKPGMSRMDLLETNARIVRGVAENIAKYAP 128


>UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2;
           Toxoplasma gondii|Rep: Mitochondrial
           malate-dehydrogenase - Toxoplasma gondii
          Length = 470

 Score = 56.8 bits (131), Expect = 6e-07
 Identities = 32/84 (38%), Positives = 48/84 (57%), Gaps = 2/84 (2%)
 Frame = +1

Query: 268 LALYDIAPVTP-GVAADLSHMNTPAKVSGH-KGPEELSAAIKDADVVVIPAGVPRKPGMN 441
           + ++D+    P G   DL  +   + V    +G  + S  +KDADV+++ AGVPRKPGM+
Sbjct: 184 VVMFDVVQDLPQGKCLDLYQLTPISGVDVRFEGSNDYSV-LKDADVIIVTAGVPRKPGMS 242

Query: 442 RDDLFNTNASIVRDIALSIAQNDP 513
           RDDL   NA I+  +  +I Q  P
Sbjct: 243 RDDLLAINAKIMGQVGEAIKQYCP 266


>UniRef50_UPI0000D571DB Cluster: PREDICTED: similar to CG7998-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG7998-PA - Tribolium castaneum
          Length = 376

 Score = 54.0 bits (124), Expect = 4e-06
 Identities = 23/43 (53%), Positives = 32/43 (74%)
 Frame = +3

Query: 510 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVV 638
           PK+ VAI   P+NS VP+ SE++KK G Y+P  + G+TT+DVV
Sbjct: 137 PKSTVAIGVEPINSVVPMFSEIMKKYGHYNPYSIFGITTVDVV 179



 Score = 50.4 bits (115), Expect = 5e-05
 Identities = 27/86 (31%), Positives = 49/86 (56%)
 Frame = +1

Query: 259 VTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGM 438
           +  L LYD   +  G A DL++++T  +V+   G +++  A+  ++++V+ +        
Sbjct: 54  IDELCLYDTQSLE-GFANDLNYVDTKCRVTSFFGNKDIQKALTKSNIIVVLSCCHAAEPT 112

Query: 439 NRDDLFNTNASIVRDIALSIAQNDPK 516
           N   LF+ NA IV+D+A SIA+  PK
Sbjct: 113 NYASLFDRNAPIVKDLATSIAKFSPK 138



 Score = 49.6 bits (113), Expect = 8e-05
 Identities = 20/35 (57%), Positives = 27/35 (77%)
 Frame = +2

Query: 650 FVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQP 754
           FV EI G++P  V VP++GGHS  TI+P+LSQ +P
Sbjct: 184 FVAEILGLEPECVTVPIVGGHSEKTIVPVLSQAKP 218


>UniRef50_UPI00015BB1FC Cluster: malate dehydrogenase (NAD); n=1;
           Ignicoccus hospitalis KIN4/I|Rep: malate dehydrogenase
           (NAD) - Ignicoccus hospitalis KIN4/I
          Length = 311

 Score = 53.6 bits (123), Expect = 5e-06
 Identities = 30/86 (34%), Positives = 45/86 (52%), Gaps = 1/86 (1%)
 Frame = +1

Query: 259 VTRLALYDIAP-VTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPG 435
           V R+ L D  P ++ GV  D+ H     + S      +  + +++AD +VI AG PRK  
Sbjct: 30  VARMVLVDAVPGLSKGVMEDIKHAAAVFRRSIQVEAYDDVSKVENADAIVITAGKPRKAD 89

Query: 436 MNRDDLFNTNASIVRDIALSIAQNDP 513
           M+R DL   NA I+RDI   +   +P
Sbjct: 90  MSRRDLAKVNAQIIRDIGDKLRDRNP 115


>UniRef50_Q8ZVB2 Cluster: Malate dehydrogenase; n=14;
           Thermoprotei|Rep: Malate dehydrogenase - Pyrobaculum
           aerophilum
          Length = 309

 Score = 53.2 bits (122), Expect = 7e-06
 Identities = 31/88 (35%), Positives = 49/88 (55%), Gaps = 2/88 (2%)
 Frame = +1

Query: 256 LVTRLALYDIAPVTP-GVAADLSHMNTPAKVS-GHKGPEELSAAIKDADVVVIPAGVPRK 429
           L  ++ L DI    P G A D++HM++   +   + G  E    I+ +D++++ AG+PRK
Sbjct: 23  LDNKILLIDIVKGLPQGEALDMNHMSSILGLDVEYVGSNEYKD-IEGSDLIIVTAGLPRK 81

Query: 430 PGMNRDDLFNTNASIVRDIALSIAQNDP 513
           PGM R+ L   NA IV +I   I +  P
Sbjct: 82  PGMTREQLLEANAKIVAEIGREIKKYAP 109


>UniRef50_UPI00015B4591 Cluster: PREDICTED: similar to mitochondrial
           malate dehydrogenase; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to mitochondrial malate dehydrogenase
           - Nasonia vitripennis
          Length = 299

 Score = 52.8 bits (121), Expect = 9e-06
 Identities = 21/50 (42%), Positives = 35/50 (70%)
 Frame = +3

Query: 510 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVVALPPSSA 659
           PKA+VA+ T+PV +T+P+ SE+ K +G +DPNR+ G   L+ + +   +A
Sbjct: 93  PKALVAVFTHPVTATLPLVSEIYKYSGDWDPNRIFGSAALESMRISAMTA 142



 Score = 33.5 bits (73), Expect = 5.9
 Identities = 10/28 (35%), Positives = 22/28 (78%)
 Frame = +2

Query: 671 VDPTSVAVPVIGGHSGITIIPILSQCQP 754
           ++P+ ++VP+ GG   +T++P+LS+ +P
Sbjct: 147 LNPSFISVPIAGGIDSLTVVPLLSRARP 174


>UniRef50_A6Q7S2 Cluster: Malate dehydrogenase, NAD-dependent; n=1;
           Sulfurovum sp. NBC37-1|Rep: Malate dehydrogenase,
           NAD-dependent - Sulfurovum sp. (strain NBC37-1)
          Length = 320

 Score = 52.8 bits (121), Expect = 9e-06
 Identities = 34/83 (40%), Positives = 45/83 (54%), Gaps = 4/83 (4%)
 Frame = +1

Query: 277 YDIAPVTPGVAADLSHMNTPAK----VSGHKGPEELSAAIKDADVVVIPAGVPRKPGMNR 444
           YD+A    G A D+S     A+    V   KGPE++  +    DVV+I AG PR PGM+R
Sbjct: 39  YDVAK---GKALDMSQAANAARQHTIVKAAKGPEDMEGS----DVVIITAGAPRTPGMSR 91

Query: 445 DDLFNTNASIVRDIALSIAQNDP 513
           DDL   NA IV+  +  I +  P
Sbjct: 92  DDLLFKNADIVKCYSREIKEYAP 114


>UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=1;
           Entamoeba histolytica|Rep: NAD-specific malate
           dehydrogenase 2 - Entamoeba histolytica
          Length = 329

 Score = 52.8 bits (121), Expect = 9e-06
 Identities = 28/71 (39%), Positives = 41/71 (57%), Gaps = 1/71 (1%)
 Frame = +1

Query: 268 LALYDIAPVT-PGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMNR 444
           L LYD+  +   G++ +L+    P K+ G     E++ A  + DV +I AGVPRKPGM R
Sbjct: 47  LHLYDLNDMALKGLSMELTDCCLP-KLKGIISTTEIALAFSNVDVAIIVAGVPRKPGMQR 105

Query: 445 DDLFNTNASIV 477
            DL N N  ++
Sbjct: 106 SDLINVNKKVM 116


>UniRef50_UPI0000DB76D8 Cluster: PREDICTED: similar to CG7998-PA;
           n=2; Apis mellifera|Rep: PREDICTED: similar to CG7998-PA
           - Apis mellifera
          Length = 333

 Score = 52.0 bits (119), Expect = 2e-05
 Identities = 19/41 (46%), Positives = 31/41 (75%)
 Frame = +3

Query: 510 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLD 632
           P+A++AI+ NP+NS +P+  E+ KKAG+Y+ NR+ GV   +
Sbjct: 108 PQAMLAIVMNPINSLIPLTMEMYKKAGIYEYNRIFGVMNFE 148



 Score = 41.1 bits (92), Expect = 0.029
 Identities = 26/90 (28%), Positives = 50/90 (55%), Gaps = 1/90 (1%)
 Frame = +1

Query: 256 LVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEE-LSAAIKDADVVVIPAGVPRKP 432
           L+  LA++D    T G+A DL++++T  KVS    PE+ L   ++ A +V+I   V  + 
Sbjct: 25  LIDELAIFDNNSSTYGLALDLNYIDTKCKVSTCNHPEKCLEETLQGAKIVMI---VTDRT 81

Query: 433 GMNRDDLFNTNASIVRDIALSIAQNDPKLL 522
               +++  +NA I+ D+  +I +  P+ +
Sbjct: 82  SNESNEVLKSNAIILSDLLPNIIKFSPQAM 111



 Score = 34.7 bits (76), Expect = 2.5
 Identities = 13/37 (35%), Positives = 22/37 (59%)
 Frame = +2

Query: 647 TFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQPA 757
           +F  ++  ++P    +PVIGG    T IP+ SQ +P+
Sbjct: 154 SFTADLINIEPECTMIPVIGGGCSETCIPLFSQAKPS 190


>UniRef50_P11386 Cluster: Malate dehydrogenase; n=6;
           Sulfolobaceae|Rep: Malate dehydrogenase - Sulfolobus
           acidocaldarius
          Length = 306

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 31/92 (33%), Positives = 44/92 (47%), Gaps = 1/92 (1%)
 Frame = +1

Query: 238 STEAESLVTRLALYDIAPVTPG-VAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPA 414
           +T        + LYD+ P  P     ++ H     +V            I  AD+VVI A
Sbjct: 19  NTIVNGYADEVMLYDVVPELPEKFEHEIRHALAALRVKTELLSTNNIDDISGADIVVITA 78

Query: 415 GVPRKPGMNRDDLFNTNASIVRDIALSIAQND 510
           G PRKPGM+R DLF  NA I+ D+A  + + +
Sbjct: 79  GKPRKPGMSRRDLFIDNAKIMIDLAKKLPKKN 110


>UniRef50_A4L2P0 Cluster: L-lactate dehydrogenase; n=4;
           Lactobacillus|Rep: L-lactate dehydrogenase -
           Lactobacillus reuteri
          Length = 312

 Score = 51.2 bits (117), Expect = 3e-05
 Identities = 29/66 (43%), Positives = 41/66 (62%)
 Frame = +1

Query: 310 ADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMNRDDLFNTNASIVRDIA 489
           AD++ +  P K+  + G  E +A   DADVVVI AG+PRKPG  R DL N N +I++ I 
Sbjct: 53  ADITPLTNPVKI--YAGTYEDAA---DADVVVITAGIPRKPGETRLDLVNKNTTILKSII 107

Query: 490 LSIAQN 507
             I ++
Sbjct: 108 KPIVKS 113


>UniRef50_Q4Q3J5 Cluster: Malate dehydrogenase, putative; n=5;
           Trypanosomatidae|Rep: Malate dehydrogenase, putative -
           Leishmania major
          Length = 342

 Score = 50.8 bits (116), Expect = 4e-05
 Identities = 19/39 (48%), Positives = 31/39 (79%)
 Frame = +3

Query: 522 VAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVV 638
           VA++++PVN+  P  +E+LK +G +DP ++ GVTTLDV+
Sbjct: 133 VAVVSSPVNALTPFCAELLKASGKFDPRKLFGVTTLDVI 171


>UniRef50_Q64P62 Cluster: Malate dehydrogenase; n=28;
           Bacteroidetes|Rep: Malate dehydrogenase - Bacteroides
           fragilis
          Length = 313

 Score = 50.4 bits (115), Expect = 5e-05
 Identities = 21/49 (42%), Positives = 33/49 (67%)
 Frame = +1

Query: 376 AAIKDADVVVIPAGVPRKPGMNRDDLFNTNASIVRDIALSIAQNDPKLL 522
           A   ++DVVVI +G+PRKPGM R++L   NA IV+ +A ++ +  P  +
Sbjct: 67  AQTANSDVVVITSGIPRKPGMTREELIGVNAGIVKSVAENLLKYSPNAI 115


>UniRef50_Q6A9C3 Cluster: L-lactate dehydrogenase; n=2;
           Propionibacterium acnes|Rep: L-lactate dehydrogenase -
           Propionibacterium acnes
          Length = 319

 Score = 50.4 bits (115), Expect = 5e-05
 Identities = 35/89 (39%), Positives = 47/89 (52%), Gaps = 3/89 (3%)
 Frame = +1

Query: 268 LALYDIAP-VTPGVAADLSHMN--TPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGM 438
           ++LYDIA        ADL+H    TPA V G  G +    A  D+DVV I AG  +KPG 
Sbjct: 38  VSLYDIAKDKVEAEVADLAHGTQFTPASVMG--GADVHDTA--DSDVVFITAGARQKPGQ 93

Query: 439 NRDDLFNTNASIVRDIALSIAQNDPKLLW 525
            R DL   NA+I+R +   + +  P  L+
Sbjct: 94  TRLDLAGVNANILRSLMPQLVEQSPNALF 122


>UniRef50_Q979N9 Cluster: Malate dehydrogenase; n=4;
           Thermoplasmatales|Rep: Malate dehydrogenase -
           Thermoplasma volcanium
          Length = 325

 Score = 49.6 bits (113), Expect = 8e-05
 Identities = 19/44 (43%), Positives = 33/44 (75%)
 Frame = +1

Query: 382 IKDADVVVIPAGVPRKPGMNRDDLFNTNASIVRDIALSIAQNDP 513
           ++ +DV+V+ AG+ RKPGM+R+DLF+ N  I+ D++ +I +  P
Sbjct: 74  MEGSDVIVVTAGMARKPGMSREDLFDKNVEIIADVSKNIKKYSP 117


>UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter
           hepaticus|Rep: Malate dehydrogenase - Helicobacter
           hepaticus
          Length = 315

 Score = 49.6 bits (113), Expect = 8e-05
 Identities = 29/82 (35%), Positives = 47/82 (57%), Gaps = 4/82 (4%)
 Frame = +1

Query: 289 PVTPGVAADLSH----MNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMNRDDLF 456
           P   GV  D+S      + P  + G    EE++    +++VV+I AG PR P M R+DL 
Sbjct: 39  PRCKGVGLDISQAAAIFDIPILIKGCNSYEEIA----ESEVVIITAGFPRTPNMTRNDLL 94

Query: 457 NTNASIVRDIALSIAQNDPKLL 522
             NASI+++I+ ++A+  P+ L
Sbjct: 95  LKNASIIQEISSNVARIAPQSL 116


>UniRef50_Q18WQ6 Cluster: Malate dehydrogenase, NAD-dependent; n=2;
           Desulfitobacterium hafniense|Rep: Malate dehydrogenase,
           NAD-dependent - Desulfitobacterium hafniense (strain
           DCB-2)
          Length = 320

 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 21/42 (50%), Positives = 30/42 (71%)
 Frame = +1

Query: 388 DADVVVIPAGVPRKPGMNRDDLFNTNASIVRDIALSIAQNDP 513
           D+DVVVI AG+ RKPGM+R++L + NA IV  +   + Q+ P
Sbjct: 71  DSDVVVITAGIARKPGMSRNELCDINAGIVTHVVRQVVQHSP 112


>UniRef50_A2SNY0 Cluster: Malate/lactate dehydrogenases-like
           protein; n=1; Methylibium petroleiphilum PM1|Rep:
           Malate/lactate dehydrogenases-like protein - Methylibium
           petroleiphilum (strain PM1)
          Length = 432

 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 32/91 (35%), Positives = 47/91 (51%), Gaps = 2/91 (2%)
 Frame = +1

Query: 247 AES-LVTRLALYDIAP-VTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGV 420
           AES L + +AL D+ P +  G+A D+ H       S      +   A+  A+ +VI AG 
Sbjct: 143 AESDLFSEVALVDVVPGLAAGLALDMWHGAGLYGFSTRLSGSDDLVALAGAEYIVITAGK 202

Query: 421 PRKPGMNRDDLFNTNASIVRDIALSIAQNDP 513
           PR+PGM+R DL   NA I+  +   I  + P
Sbjct: 203 PRQPGMSRTDLTVVNAEIMTSVCRGIRTHAP 233


>UniRef50_Q3J7E7 Cluster: Malate dehydrogenase; n=5;
           Gammaproteobacteria|Rep: Malate dehydrogenase -
           Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
          Length = 311

 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 34/94 (36%), Positives = 49/94 (52%), Gaps = 5/94 (5%)
 Frame = +1

Query: 256 LVTRLALYDIAP-VTPGVAADLSH----MNTPAKVSGHKGPEELSAAIKDADVVVIPAGV 420
           L   L L D    V  G A D+       +  A+V+G    E     I D+D+VVI AG 
Sbjct: 27  LCRELVLLDAQEGVAQGAALDIQQSAPLFDFDARVTGSTNYE----LIADSDLVVITAGK 82

Query: 421 PRKPGMNRDDLFNTNASIVRDIALSIAQNDPKLL 522
           PRKPGM+R D+ ++N  I+ DI  ++ +  P+ L
Sbjct: 83  PRKPGMSRSDVLDSNLPIITDIMNNVMRFAPQSL 116


>UniRef50_A2Q223 Cluster: Lactate/malate dehydrogenase, alpha/beta
           C-terminal domain containing protein; n=1; Medicago
           truncatula|Rep: Lactate/malate dehydrogenase, alpha/beta
           C-terminal domain containing protein - Medicago
           truncatula (Barrel medic)
          Length = 205

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 19/31 (61%), Positives = 26/31 (83%)
 Frame = +2

Query: 659 EINGVDPTSVAVPVIGGHSGITIIPILSQCQ 751
           E+ GVDP  V VPV+GGH+G+TI+P+LSQ +
Sbjct: 27  EVLGVDPREVDVPVVGGHAGVTILPLLSQAK 57


>UniRef50_Q7M9A7 Cluster: Malate dehydrogenase; n=4;
           Epsilonproteobacteria|Rep: Malate dehydrogenase -
           Wolinella succinogenes
          Length = 314

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 23/62 (37%), Positives = 34/62 (54%)
 Frame = +1

Query: 301 GVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMNRDDLFNTNASIVR 480
           G+A D+ H  +  K           + ++  DVVV  AG PR+PGM+RDDL   NA ++R
Sbjct: 38  GIALDMGHAASATKTHTIVRVANEPSDLRGCDVVVFCAGSPRQPGMSRDDLLLANAKVIR 97

Query: 481 DI 486
            +
Sbjct: 98  TV 99


>UniRef50_Q8TWG5 Cluster: Malate dehydrogenase; n=2;
           Euryarchaeota|Rep: Malate dehydrogenase - Methanopyrus
           kandleri
          Length = 317

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 20/45 (44%), Positives = 31/45 (68%)
 Frame = +1

Query: 388 DADVVVIPAGVPRKPGMNRDDLFNTNASIVRDIALSIAQNDPKLL 522
           DADV+V+ AG+PRKPG  R DL   NA+I++     +A+ +P+ +
Sbjct: 73  DADVIVMTAGIPRKPGQTRLDLTKDNAAIIKKYLEGVAEENPEAI 117


>UniRef50_A7DRG3 Cluster: Lactate/malate dehydrogenase; n=1;
           Candidatus Nitrosopumilus maritimus SCM1|Rep:
           Lactate/malate dehydrogenase - Candidatus Nitrosopumilus
           maritimus SCM1
          Length = 304

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 27/79 (34%), Positives = 43/79 (54%), Gaps = 1/79 (1%)
 Frame = +1

Query: 265 RLALYDIAPVTP-GVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMN 441
           ++ L D+A   P G A D++HM +   +            +K +++VV+ AG  RKPGM 
Sbjct: 26  QILLLDVAEGLPQGEAMDINHMLSEQGIDVEVKGSNNFEDMKGSNIVVVVAGSGRKPGMT 85

Query: 442 RDDLFNTNASIVRDIALSI 498
           R DL   NASIV+ +  ++
Sbjct: 86  RMDLLKINASIVKSVVENV 104


>UniRef50_UPI0000D55CD8 Cluster: PREDICTED: similar to Malate
           DeHydrogenase family member (mdh-1); n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to Malate
           DeHydrogenase family member (mdh-1) - Tribolium
           castaneum
          Length = 374

 Score = 48.0 bits (109), Expect = 3e-04
 Identities = 27/89 (30%), Positives = 48/89 (53%)
 Frame = +1

Query: 259 VTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGM 438
           +  L L+D    T   A DL+ ++T  K+      + L  AI  A VV+   G   KPG 
Sbjct: 54  IYELRLFDEENNTNAFACDLNEIDTRTKLKSFSC-KSLKNAIVGAHVVISTGGCQEKPGS 112

Query: 439 NRDDLFNTNASIVRDIALSIAQNDPKLLW 525
           ++ +LF+ N   VR++A+ +A+ +P+ ++
Sbjct: 113 SQRELFDKNLDNVRNVAMFLAEFNPEAIY 141



 Score = 44.0 bits (99), Expect = 0.004
 Identities = 19/40 (47%), Positives = 26/40 (65%)
 Frame = +3

Query: 510 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTL 629
           P+AI  I   PV + VP+ SE  KKA  YDP +++GV T+
Sbjct: 137 PEAIYCIAKPPVEALVPMVSEEYKKAETYDPRKIIGVATV 176



 Score = 37.9 bits (84), Expect = 0.27
 Identities = 17/36 (47%), Positives = 22/36 (61%)
 Frame = +2

Query: 647 TFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQP 754
           TF+ E    +P  V  P+IGG S  T IP+LSQ +P
Sbjct: 183 TFIAEHTNQNPADVLCPIIGGLSPKTTIPVLSQTKP 218


>UniRef50_A0RXX8 Cluster: Malate/L-lactate dehydrogenase; n=1;
           Cenarchaeum symbiosum|Rep: Malate/L-lactate
           dehydrogenase - Cenarchaeum symbiosum
          Length = 302

 Score = 48.0 bits (109), Expect = 3e-04
 Identities = 29/86 (33%), Positives = 46/86 (53%), Gaps = 2/86 (2%)
 Frame = +1

Query: 256 LVTRLALYDIAPVTP-GVAADLSHMNTPAKVSGH-KGPEELSAAIKDADVVVIPAGVPRK 429
           L + + L DI    P G A D++HM     +    +G  + S  ++ +D+VV+ AG  RK
Sbjct: 23  LDSEILLLDIVEGLPQGEAMDINHMLAEQGIDTEVRGSNDYSD-MEGSDIVVVVAGAGRK 81

Query: 430 PGMNRDDLFNTNASIVRDIALSIAQN 507
           PGM R DL   NA IV+ +   + ++
Sbjct: 82  PGMTRMDLLKINAGIVKGVVEKVKEH 107


>UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|Rep:
           Malate dehydrogenase 1 - Aquifex aeolicus
          Length = 335

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 28/68 (41%), Positives = 41/68 (60%), Gaps = 2/68 (2%)
 Frame = +1

Query: 316 LSHMNTPAKVSGHK-GPE-ELSAAIKDADVVVIPAGVPRKPGMNRDDLFNTNASIVRDIA 489
           L+ M+  A+V G+   PE E    ++ +D+VVI AG PR+PGM+R+DL   N  I+  IA
Sbjct: 59  LAAMDIDARVEGYTVTPEGEGYEPLEGSDIVVITAGFPRRPGMSREDLLEANIRIISVIA 118

Query: 490 LSIAQNDP 513
             I +  P
Sbjct: 119 DRIKRYAP 126


>UniRef50_P59390 Cluster: L-lactate dehydrogenase 2; n=8;
           Lactobacillus|Rep: L-lactate dehydrogenase 2 -
           Lactobacillus plantarum
          Length = 309

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 22/37 (59%), Positives = 26/37 (70%)
 Frame = +1

Query: 376 AAIKDADVVVIPAGVPRKPGMNRDDLFNTNASIVRDI 486
           A  +DAD+VVI AGVPRKPG +R DL N N  I+  I
Sbjct: 68  ADARDADIVVITAGVPRKPGESRLDLINRNTKILESI 104


>UniRef50_Q81K80 Cluster: L-lactate dehydrogenase 2; n=12;
           Firmicutes|Rep: L-lactate dehydrogenase 2 - Bacillus
           anthracis
          Length = 314

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 30/66 (45%), Positives = 34/66 (51%)
 Frame = +1

Query: 301 GVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMNRDDLFNTNASIVR 480
           G A DLSH   P   S  K      A  KDAD+VVI AG+P+KPG  R DL   N  I +
Sbjct: 45  GEAMDLSHA-VPFSPSPTKVWSGSYADCKDADLVVITAGLPQKPGETRLDLVEKNTKIFK 103

Query: 481 DIALSI 498
            I   I
Sbjct: 104 QIVRGI 109


>UniRef50_UPI0000DB6C4F Cluster: PREDICTED: similar to Malate
           DeHydrogenase family member (mdh-1); n=1; Apis
           mellifera|Rep: PREDICTED: similar to Malate
           DeHydrogenase family member (mdh-1) - Apis mellifera
          Length = 221

 Score = 46.4 bits (105), Expect = 8e-04
 Identities = 18/40 (45%), Positives = 29/40 (72%)
 Frame = +3

Query: 513 KAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLD 632
           +++VA+   PV +T+P  SE+ K AG +DP+R++G T LD
Sbjct: 11  ESLVAVFVRPVTATLPTVSEIYKLAGWWDPDRIIGSTALD 50


>UniRef50_Q07841 Cluster: Malate dehydrogenase; n=7;
           Halobacteriaceae|Rep: Malate dehydrogenase - Haloarcula
           marismortui (Halobacterium marismortui)
          Length = 304

 Score = 46.0 bits (104), Expect = 0.001
 Identities = 29/73 (39%), Positives = 42/73 (57%), Gaps = 1/73 (1%)
 Frame = +1

Query: 295 TPGVAADLSH-MNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMNRDDLFNTNAS 471
           T G AAD +H +   +     +G  E +A    +DVVVI AG+PR+PG  R DL   NA 
Sbjct: 42  TVGQAADTNHGIAYDSNTRVRQGGYEDTAG---SDVVVITAGIPRQPGQTRIDLAGDNAP 98

Query: 472 IVRDIALSIAQND 510
           I+ DI  S+ +++
Sbjct: 99  IMEDIQSSLDEHN 111


>UniRef50_A7GYI6 Cluster: Lactate/malate dehydrogenase, NAD binding
           domain protein; n=2; Campylobacter|Rep: Lactate/malate
           dehydrogenase, NAD binding domain protein -
           Campylobacter curvus 525.92
          Length = 297

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 21/49 (42%), Positives = 31/49 (63%)
 Frame = +1

Query: 376 AAIKDADVVVIPAGVPRKPGMNRDDLFNTNASIVRDIALSIAQNDPKLL 522
           A I+ +D+VV+ AG PRK G  R+DL   NA +V+  A +IA+  P  +
Sbjct: 65  ALIEASDIVVVTAGSPRKEGQTREDLLLKNAQVVKQTAQNIAKFAPNAI 113


>UniRef50_P16115 Cluster: L-lactate dehydrogenase; n=4;
           Thermotogaceae|Rep: L-lactate dehydrogenase - Thermotoga
           maritima
          Length = 319

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 19/46 (41%), Positives = 32/46 (69%)
 Frame = +1

Query: 376 AAIKDADVVVIPAGVPRKPGMNRDDLFNTNASIVRDIALSIAQNDP 513
           A +K +DVV++ AGVP+KPG  R  L   NA ++++IA ++++  P
Sbjct: 63  ADLKGSDVVIVAAGVPQKPGETRLQLLGRNARVMKEIARNVSKYAP 108


>UniRef50_P0C0J4 Cluster: L-lactate dehydrogenase; n=5; Mycoplasma
           hyopneumoniae|Rep: L-lactate dehydrogenase - Mycoplasma
           hyopneumoniae
          Length = 315

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 20/42 (47%), Positives = 29/42 (69%)
 Frame = +1

Query: 382 IKDADVVVIPAGVPRKPGMNRDDLFNTNASIVRDIALSIAQN 507
           +KDAD +VI AG P+KPG  R +L   N  I+R+IAL + ++
Sbjct: 69  LKDADFIVITAGRPQKPGETRLELVADNIRIIREIALKVKES 110


>UniRef50_Q017A7 Cluster: Chromosome 06 contig 1, DNA sequence; n=1;
           Ostreococcus tauri|Rep: Chromosome 06 contig 1, DNA
           sequence - Ostreococcus tauri
          Length = 131

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 22/37 (59%), Positives = 24/37 (64%)
 Frame = -2

Query: 407 MTTTSASLMAADSSSGPLWPLTLAGVFMWERSAATPG 297
           M TTS S  AA SS+ P +P T A VF  E SAATPG
Sbjct: 1   MITTSQSFSAAPSSASPAYPFTCAAVFTCETSAATPG 37


>UniRef50_Q892U0 Cluster: L-lactate dehydrogenase; n=12;
           Bacteria|Rep: L-lactate dehydrogenase - Clostridium
           tetani
          Length = 316

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 33/91 (36%), Positives = 44/91 (48%), Gaps = 2/91 (2%)
 Frame = +1

Query: 250 ESLVTRLALYDI-APVTPGVAADLSHMNTPAK-VSGHKGPEELSAAIKDADVVVIPAGVP 423
           E L + + + DI      G A DLSH  +  K V    G  E +   KD+D+V+I AG  
Sbjct: 27  EGLASEIVIVDINKEKAKGEAMDLSHGVSFVKPVDIIAGDYEDT---KDSDIVIITAGAG 83

Query: 424 RKPGMNRDDLFNTNASIVRDIALSIAQNDPK 516
            KPG  R DL N N  I + I   + +  PK
Sbjct: 84  PKPGETRLDLINKNYEIFKGIVPEVVKYSPK 114


>UniRef50_A5Z9B1 Cluster: Putative uncharacterized protein; n=1;
           Eubacterium ventriosum ATCC 27560|Rep: Putative
           uncharacterized protein - Eubacterium ventriosum ATCC
           27560
          Length = 312

 Score = 43.6 bits (98), Expect = 0.005
 Identities = 19/38 (50%), Positives = 26/38 (68%)
 Frame = +1

Query: 385 KDADVVVIPAGVPRKPGMNRDDLFNTNASIVRDIALSI 498
           KDAD++VI AGVPR PG  R D+ + +   VRDI  ++
Sbjct: 71  KDADIIVISAGVPRLPGQTRLDVLDGSVECVRDIVSNL 108


>UniRef50_Q27743 Cluster: L-lactate dehydrogenase; n=17;
           Apicomplexa|Rep: L-lactate dehydrogenase - Plasmodium
           falciparum (isolate CDC / Honduras)
          Length = 316

 Score = 43.6 bits (98), Expect = 0.005
 Identities = 35/92 (38%), Positives = 46/92 (50%), Gaps = 10/92 (10%)
 Frame = +1

Query: 268 LALYDIAPVTP-GVAADLSHMNTPA----KVSGHKGPEELSAAIKDADVVVIPAGVPRKP 432
           + L+DI    P G A D SH N  A    KVSG    ++L+ A    DVV++ AG  + P
Sbjct: 31  VVLFDIVKNMPHGKALDTSHTNVMAYSNCKVSGSNTYDDLAGA----DVVIVTAGFTKAP 86

Query: 433 G-----MNRDDLFNTNASIVRDIALSIAQNDP 513
           G      NRDDL   N  I+ +I   I +N P
Sbjct: 87  GKSDKEWNRDDLLPLNNKIMIEIGGHIKKNCP 118


>UniRef50_A3EWH3 Cluster: Malate/lactate dehydrogenase; n=1;
           Leptospirillum sp. Group II UBA|Rep: Malate/lactate
           dehydrogenase - Leptospirillum sp. Group II UBA
          Length = 320

 Score = 43.2 bits (97), Expect = 0.007
 Identities = 19/44 (43%), Positives = 30/44 (68%)
 Frame = +1

Query: 382 IKDADVVVIPAGVPRKPGMNRDDLFNTNASIVRDIALSIAQNDP 513
           I+ + VVV+ AG  RKPGM+R+DL + N  I+ ++A  I ++ P
Sbjct: 72  IEGSSVVVVTAGFSRKPGMSREDLLHKNGDIMIEVAEKIRKHAP 115


>UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex
           aeolicus|Rep: Malate dehydrogenase 2 - Aquifex aeolicus
          Length = 334

 Score = 42.7 bits (96), Expect = 0.010
 Identities = 21/60 (35%), Positives = 34/60 (56%)
 Frame = +1

Query: 325 MNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMNRDDLFNTNASIVRDIALSIAQ 504
           M+    V G    +E    +K +D+VVI AG+PR+ GM+R+DL   N  I++    +I +
Sbjct: 67  MDIDINVKGISYDKEGFEELKGSDIVVITAGIPRREGMSREDLLYENLKILKKFTDAIKE 126


>UniRef50_A0RPE9 Cluster: Malate dehydrogenase; n=1; Campylobacter
           fetus subsp. fetus 82-40|Rep: Malate dehydrogenase -
           Campylobacter fetus subsp. fetus (strain 82-40)
          Length = 306

 Score = 42.3 bits (95), Expect = 0.013
 Identities = 21/45 (46%), Positives = 28/45 (62%)
 Frame = +1

Query: 382 IKDADVVVIPAGVPRKPGMNRDDLFNTNASIVRDIALSIAQNDPK 516
           +KD D+VVI AG  RK G +RDDL   NA IV   +  +++  PK
Sbjct: 67  LKDFDIVVITAGFARKDGQSRDDLAMMNAKIVSHSSKMVSKFAPK 111


>UniRef50_Q7NHJ3 Cluster: Malate dehydrogenase; n=13; cellular
           organisms|Rep: Malate dehydrogenase - Gloeobacter
           violaceus
          Length = 325

 Score = 41.9 bits (94), Expect = 0.017
 Identities = 18/42 (42%), Positives = 27/42 (64%)
 Frame = +1

Query: 391 ADVVVIPAGVPRKPGMNRDDLFNTNASIVRDIALSIAQNDPK 516
           +DV+V+ AG  R+PGM+RDDL  TN  IV ++      + P+
Sbjct: 77  SDVLVVAAGFARQPGMSRDDLLLTNTRIVFEVTQKAVAHSPE 118


>UniRef50_UPI0000D56DC5 Cluster: PREDICTED: similar to Malate
           dehydrogenase, mitochondrial precursor; n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to Malate
           dehydrogenase, mitochondrial precursor - Tribolium
           castaneum
          Length = 349

 Score = 41.5 bits (93), Expect = 0.022
 Identities = 16/40 (40%), Positives = 26/40 (65%)
 Frame = +3

Query: 510 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTL 629
           PKA++ +   P++ T+PI +EV K++  Y P R+LG   L
Sbjct: 130 PKAVIVVAVTPISVTLPIVAEVYKQSDWYHPGRLLGSAAL 169


>UniRef50_Q7MTK2 Cluster: Malate dehydrogenase; n=4;
           Bacteroidales|Rep: Malate dehydrogenase - Porphyromonas
           gingivalis (Bacteroides gingivalis)
          Length = 334

 Score = 41.5 bits (93), Expect = 0.022
 Identities = 28/87 (32%), Positives = 36/87 (41%), Gaps = 1/87 (1%)
 Frame = +1

Query: 256 LVTRLALYD-IAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKP 432
           L   L LYD  A    GVA ++ H              ++  A+ DA  +V   G PRK 
Sbjct: 31  LTPNLCLYDPFAVGLEGVAEEIRHCGFEGL--NLTFTSDIKEALTDAKYIVSSGGAPRKE 88

Query: 433 GMNRDDLFNTNASIVRDIALSIAQNDP 513
           GM R+DL   NA I   +   I    P
Sbjct: 89  GMTREDLLKGNAEIAAQLGKDIKSYCP 115


>UniRef50_Q8I8U4 Cluster: Lactate dehydrogenase; n=3;
           Eimeriorina|Rep: Lactate dehydrogenase - Eimeria tenella
          Length = 331

 Score = 41.5 bits (93), Expect = 0.022
 Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 6/88 (6%)
 Frame = +1

Query: 268 LALYDIAPVTP-GVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPG--- 435
           + L+D+ P  P G A DL H    A            A+++ ADVV+I AG+ +  G   
Sbjct: 36  VVLFDVVPNMPAGKALDLCHTAAVADNGVRVQGANSYASLEGADVVIITAGITKAAGKSD 95

Query: 436 --MNRDDLFNTNASIVRDIALSIAQNDP 513
              +R DL   N  I+R++  +I Q  P
Sbjct: 96  QEWSRKDLLPVNVKILREVGAAIKQFCP 123


>UniRef50_UPI00015B5ACF Cluster: PREDICTED: similar to
           ENSANGP00000020184; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to ENSANGP00000020184 - Nasonia
           vitripennis
          Length = 352

 Score = 41.1 bits (92), Expect = 0.029
 Identities = 18/41 (43%), Positives = 31/41 (75%), Gaps = 1/41 (2%)
 Frame = +3

Query: 510 PKAIVAIITNPVNSTVPIASEVLKKAGVYD-PNRVLGVTTL 629
           PKA+VA+++  VNS VP+  E+ K+AG+++  +R+ GV +L
Sbjct: 144 PKALVALVSRRVNSLVPMLYELYKRAGLFEASSRIFGVVSL 184


>UniRef50_P0A3M9 Cluster: L-lactate dehydrogenase; n=140;
           Bacteria|Rep: L-lactate dehydrogenase - Streptococcus
           pneumoniae
          Length = 328

 Score = 41.1 bits (92), Expect = 0.029
 Identities = 27/69 (39%), Positives = 35/69 (50%)
 Frame = +1

Query: 301 GVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMNRDDLFNTNASIVR 480
           G A DLSH    A  S  K      +   DAD+VVI AG P+KPG  R DL   N +I +
Sbjct: 49  GDALDLSH--ALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNLAINK 106

Query: 481 DIALSIAQN 507
            I   + ++
Sbjct: 107 SIVTQVVES 115


>UniRef50_Q838C9 Cluster: L-lactate dehydrogenase 2; n=9;
           Bacilli|Rep: L-lactate dehydrogenase 2 - Enterococcus
           faecalis (Streptococcus faecalis)
          Length = 317

 Score = 41.1 bits (92), Expect = 0.029
 Identities = 19/41 (46%), Positives = 29/41 (70%)
 Frame = +1

Query: 385 KDADVVVIPAGVPRKPGMNRDDLFNTNASIVRDIALSIAQN 507
           +DAD+VVI AG  +KPG +R DL + NA I++ I  +I ++
Sbjct: 72  QDADIVVITAGANQKPGQSRLDLVSINAEIMKTIVNNIMKS 112


>UniRef50_Q23CW4 Cluster: Malate dehydrogenase, cytoplasmic,
           putative; n=3; Oligohymenophorea|Rep: Malate
           dehydrogenase, cytoplasmic, putative - Tetrahymena
           thermophila SB210
          Length = 365

 Score = 40.7 bits (91), Expect = 0.039
 Identities = 24/63 (38%), Positives = 29/63 (46%)
 Frame = +1

Query: 292 VTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMNRDDLFNTNAS 471
           +  GV  +L     P   S   G  E S   +D DV V   G PRKPGM R DL   N +
Sbjct: 89  ILQGVELELQDGAYPLLKSIKTGSNE-SILFQDVDVAVFIGGFPRKPGMERKDLLTINGN 147

Query: 472 IVR 480
           I +
Sbjct: 148 IFK 150


>UniRef50_Q98PG4 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
           pulmonis|Rep: L-lactate dehydrogenase - Mycoplasma
           pulmonis
          Length = 315

 Score = 40.7 bits (91), Expect = 0.039
 Identities = 23/69 (33%), Positives = 37/69 (53%)
 Frame = +1

Query: 301 GVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMNRDDLFNTNASIVR 480
           G A D+S        +G K      A  K AD++++ AG P+K G  R ++   N+ I++
Sbjct: 41  GHAMDMSDAIALNSTTGSKIRTGTYADAKGADLLIVAAGRPQKQGETRLEMIADNSKIMK 100

Query: 481 DIALSIAQN 507
           DIAL I ++
Sbjct: 101 DIALEIKKS 109


>UniRef50_Q6KIP9 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
           mobile|Rep: L-lactate dehydrogenase - Mycoplasma mobile
          Length = 318

 Score = 40.7 bits (91), Expect = 0.039
 Identities = 20/42 (47%), Positives = 29/42 (69%)
 Frame = +1

Query: 382 IKDADVVVIPAGVPRKPGMNRDDLFNTNASIVRDIALSIAQN 507
           +KD DVVVI AG P+KPG  R ++   NA I+ +IA +I ++
Sbjct: 71  LKDYDVVVITAGRPQKPGETRLEMVADNAKIMSNIAKNIKKS 112


>UniRef50_Q8XP62 Cluster: L-lactate dehydrogenase; n=11;
           Clostridium|Rep: L-lactate dehydrogenase - Clostridium
           perfringens
          Length = 317

 Score = 40.7 bits (91), Expect = 0.039
 Identities = 19/46 (41%), Positives = 26/46 (56%)
 Frame = +1

Query: 376 AAIKDADVVVIPAGVPRKPGMNRDDLFNTNASIVRDIALSIAQNDP 513
           A  KD+D+V+I AGV  KPG  R D+ N N  I + I   + +  P
Sbjct: 69  ADTKDSDIVIITAGVGPKPGETRLDIINKNLKIFQSIVPEVVKYSP 114


>UniRef50_O51114 Cluster: L-lactate dehydrogenase; n=4; Borrelia
           burgdorferi group|Rep: L-lactate dehydrogenase -
           Borrelia burgdorferi (Lyme disease spirochete)
          Length = 316

 Score = 40.3 bits (90), Expect = 0.051
 Identities = 31/89 (34%), Positives = 43/89 (48%), Gaps = 4/89 (4%)
 Frame = +1

Query: 253 SLVTRLALYDIAP-VTPGVAADLSHMNTPAKVSGHKGPEELSAAIKD---ADVVVIPAGV 420
           SLV  L + D+      G   DL+H     K    K    L    KD   AD+VVI AG+
Sbjct: 28  SLVHELVIIDVNENKAKGEVMDLNHGQMFLK----KNINVLFGTYKDCANADIVVITAGL 83

Query: 421 PRKPGMNRDDLFNTNASIVRDIALSIAQN 507
            +KPG  R DL + N+ I +DI  ++  +
Sbjct: 84  NQKPGETRLDLVDKNSKIFKDIITNVVSS 112


>UniRef50_A4BB89 Cluster: Lactate dehydrogenase; n=2;
           Gammaproteobacteria|Rep: Lactate dehydrogenase -
           Reinekea sp. MED297
          Length = 319

 Score = 39.9 bits (89), Expect = 0.068
 Identities = 21/47 (44%), Positives = 25/47 (53%)
 Frame = +1

Query: 382 IKDADVVVIPAGVPRKPGMNRDDLFNTNASIVRDIALSIAQNDPKLL 522
           + DAD+VVI AG   K G  RDDL   N+ I  DIA  I    P  +
Sbjct: 68  LTDADIVVITAGAQIKEGQTRDDLAEINSRITVDIAQKIETVAPNAI 114


>UniRef50_A3DCA4 Cluster: L-lactate dehydrogenase precursor; n=2;
           Clostridium|Rep: L-lactate dehydrogenase precursor -
           Clostridium thermocellum (strain ATCC 27405 / DSM 1237)
          Length = 318

 Score = 39.9 bits (89), Expect = 0.068
 Identities = 17/39 (43%), Positives = 24/39 (61%)
 Frame = +1

Query: 382 IKDADVVVIPAGVPRKPGMNRDDLFNTNASIVRDIALSI 498
           +KD DV+V+ AG  RKPG  R DL   N  I +++  +I
Sbjct: 72  VKDCDVIVVTAGANRKPGETRLDLAKKNVMIAKEVTQNI 110


>UniRef50_Q3ZZJ7 Cluster: Malate dehydrogenase; n=5; cellular
           organisms|Rep: Malate dehydrogenase - Dehalococcoides
           sp. (strain CBDB1)
          Length = 307

 Score = 39.9 bits (89), Expect = 0.068
 Identities = 16/42 (38%), Positives = 27/42 (64%)
 Frame = +1

Query: 391 ADVVVIPAGVPRKPGMNRDDLFNTNASIVRDIALSIAQNDPK 516
           +++VVI AG+ RKPGM R++L   N  I+ D+  +  +  P+
Sbjct: 70  SEIVVITAGIARKPGMTREELLAINQKIMTDVVSNCLKYSPE 111


>UniRef50_Q9GPV2 Cluster: Cytosolic malate dehydrogenase; n=4;
           Trichomonadida|Rep: Cytosolic malate dehydrogenase -
           Tetratrichomonas gallinarum
          Length = 314

 Score = 39.5 bits (88), Expect = 0.089
 Identities = 25/63 (39%), Positives = 34/63 (53%), Gaps = 3/63 (4%)
 Frame = +1

Query: 343 VSGHKGPEELSAAIKDADVVVIPAGVPRKPGMNRDDLFNTNASI--VRDIALS-IAQNDP 513
           V+G    +++  A KD DV  +    PRK GM+R DL   N  I  V+  ALS  A+ D 
Sbjct: 46  VAGIVWTDKIEEAFKDVDVAFLVGSFPRKDGMDRSDLLAKNGGIFTVQGKALSDFAKKDV 105

Query: 514 KLL 522
           K+L
Sbjct: 106 KVL 108


>UniRef50_Q6JH30 Cluster: Lactate dehydrogenase; n=3; Plasmodium
           (Plasmodium)|Rep: Lactate dehydrogenase - Plasmodium
           vivax
          Length = 299

 Score = 39.5 bits (88), Expect = 0.089
 Identities = 30/83 (36%), Positives = 42/83 (50%), Gaps = 10/83 (12%)
 Frame = +1

Query: 268 LALYDIAPVTP-GVAADLSHMNTPA----KVSGHKGPEELSAAIKDADVVVIPAGVPRKP 432
           + ++D+    P G A D SH N  A    KV+G    ++L    K ADVV++ AG  + P
Sbjct: 24  VVMFDVVKNMPQGKALDTSHSNVMAYSNCKVTGSNSYDDL----KGADVVIVTAGFTKAP 79

Query: 433 G-----MNRDDLFNTNASIVRDI 486
           G      NRDDL   N  I+ +I
Sbjct: 80  GKSDKEWNRDDLLPLNNKIMIEI 102


>UniRef50_A0D8T3 Cluster: Malate dehydrogenase; n=2; Paramecium
           tetraurelia|Rep: Malate dehydrogenase - Paramecium
           tetraurelia
          Length = 322

 Score = 39.5 bits (88), Expect = 0.089
 Identities = 17/32 (53%), Positives = 19/32 (59%)
 Frame = +1

Query: 379 AIKDADVVVIPAGVPRKPGMNRDDLFNTNASI 474
           A KDADV +    +PRKPGM R DL   N  I
Sbjct: 79  AFKDADVAIFLGAMPRKPGMERSDLLQMNREI 110


>UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;
           Candidatus Methanoregula boonei 6A8|Rep: L-lactate
           dehydrogenase precursor - Methanoregula boonei (strain
           6A8)
          Length = 332

 Score = 39.5 bits (88), Expect = 0.089
 Identities = 20/44 (45%), Positives = 26/44 (59%)
 Frame = +1

Query: 382 IKDADVVVIPAGVPRKPGMNRDDLFNTNASIVRDIALSIAQNDP 513
           +  +D+VVI AG PR PG NR DL   NA I+  +A +I    P
Sbjct: 71  VAGSDIVVITAGTPRGPGQNRLDLALGNARIIAPMARTIGTIAP 114


>UniRef50_O26290 Cluster: Malate dehydrogenase; n=2;
           Methanobacteriaceae|Rep: Malate dehydrogenase -
           Methanobacterium thermoautotrophicum
          Length = 325

 Score = 39.5 bits (88), Expect = 0.089
 Identities = 21/39 (53%), Positives = 24/39 (61%)
 Frame = +1

Query: 397 VVVIPAGVPRKPGMNRDDLFNTNASIVRDIALSIAQNDP 513
           +VVI AGVPR   M+RDDL   N  IV D A  IA+  P
Sbjct: 75  IVVITAGVPRTADMDRDDLAFKNGRIVADYARQIARFAP 113


>UniRef50_Q1FID3 Cluster: L-lactate dehydrogenase precursor; n=1;
           Clostridium phytofermentans ISDg|Rep: L-lactate
           dehydrogenase precursor - Clostridium phytofermentans
           ISDg
          Length = 325

 Score = 39.1 bits (87), Expect = 0.12
 Identities = 19/34 (55%), Positives = 22/34 (64%)
 Frame = +1

Query: 385 KDADVVVIPAGVPRKPGMNRDDLFNTNASIVRDI 486
           KDAD+VVI AG P KPG +R D    +A IV  I
Sbjct: 74  KDADIVVITAGPPPKPGQSRLDTLGLSADIVSTI 107


>UniRef50_A3CTN0 Cluster: Lactate/malate dehydrogenase; n=1;
           Methanoculleus marisnigri JR1|Rep: Lactate/malate
           dehydrogenase - Methanoculleus marisnigri (strain ATCC
           35101 / DSM 1498 / JR1)
          Length = 288

 Score = 39.1 bits (87), Expect = 0.12
 Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
 Frame = +1

Query: 247 AESLVTRLALYDI-APVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVP 423
           A  LV  + +YD+  P+      DL H      +S        +AA++DAD+ V  AG P
Sbjct: 22  ALGLVDEIVVYDVYEPLLRAQVLDLQHTGIDVAISTE------TAAMRDADIFVFAAGTP 75

Query: 424 RKPGM-NRDDLFNTNASIVR 480
           R P +  R DL   N  + +
Sbjct: 76  RTPDIKTRADLLEANIPVAK 95


>UniRef50_P62056 Cluster: L-lactate dehydrogenase; n=2;
           Bacteria|Rep: L-lactate dehydrogenase - Treponema
           denticola
          Length = 315

 Score = 39.1 bits (87), Expect = 0.12
 Identities = 18/40 (45%), Positives = 26/40 (65%)
 Frame = +1

Query: 388 DADVVVIPAGVPRKPGMNRDDLFNTNASIVRDIALSIAQN 507
           D+D+VV+ AG  ++ G  R DL   NASI+  IA  IA++
Sbjct: 72  DSDIVVVTAGAKQQSGETRIDLLKRNASIITGIAKDIAES 111


>UniRef50_Q6F0L9 Cluster: L-lactate dehydrogenase; n=6;
           Mollicutes|Rep: L-lactate dehydrogenase - Mesoplasma
           florum (Acholeplasma florum)
          Length = 317

 Score = 38.7 bits (86), Expect = 0.16
 Identities = 18/38 (47%), Positives = 27/38 (71%)
 Frame = +1

Query: 385 KDADVVVIPAGVPRKPGMNRDDLFNTNASIVRDIALSI 498
           KDAD++VI AG P++PG  R +L   N+ I++ IA +I
Sbjct: 72  KDADLIVITAGRPQRPGETRLELIADNSRIMKGIAEAI 109


>UniRef50_P62051 Cluster: L-lactate dehydrogenase; n=2;
           Desulfovibrio vulgaris subsp. vulgaris|Rep: L-lactate
           dehydrogenase - Desulfovibrio vulgaris (strain
           Hildenborough / ATCC 29579 / NCIMB8303)
          Length = 309

 Score = 37.9 bits (84), Expect = 0.27
 Identities = 19/43 (44%), Positives = 26/43 (60%), Gaps = 2/43 (4%)
 Frame = +1

Query: 391 ADVVVIPAGVPRKPGMNRDDLFNTNASIVRDIALSIAQ--NDP 513
           A +VV+ AG  + PG +R DL   NA I RDI  ++ Q  +DP
Sbjct: 69  ARIVVVTAGAKQMPGQSRLDLVRVNAGITRDILTAVMQYADDP 111


>UniRef50_Q03BE6 Cluster: L-lactate dehydrogenase; n=1;
           Lactobacillus casei ATCC 334|Rep: L-lactate
           dehydrogenase - Lactobacillus casei (strain ATCC 334)
          Length = 312

 Score = 37.5 bits (83), Expect = 0.36
 Identities = 17/38 (44%), Positives = 25/38 (65%)
 Frame = +1

Query: 385 KDADVVVIPAGVPRKPGMNRDDLFNTNASIVRDIALSI 498
           K AD++VI AG+ +KPG  R  L   NA I+++I  +I
Sbjct: 70  KYADIIVITAGIAQKPGQTRLQLLAINAKIMKEITHNI 107


>UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2;
           Ascomycota|Rep: Probable L-lactate dehydrogenase -
           Schizosaccharomyces pombe (Fission yeast)
          Length = 330

 Score = 36.7 bits (81), Expect = 0.63
 Identities = 18/40 (45%), Positives = 23/40 (57%)
 Frame = +1

Query: 385 KDADVVVIPAGVPRKPGMNRDDLFNTNASIVRDIALSIAQ 504
           KDA  VVI AG  +KPG  R DL   N SI ++I   + +
Sbjct: 86  KDATAVVITAGKNQKPGETRMDLLKANISIFKEILREVTK 125


>UniRef50_P61973 Cluster: Malate dehydrogenase; n=43; Bacteria|Rep:
           Malate dehydrogenase - Bdellovibrio bacteriovorus
          Length = 335

 Score = 36.3 bits (80), Expect = 0.83
 Identities = 16/34 (47%), Positives = 19/34 (55%)
 Frame = +1

Query: 373 SAAIKDADVVVIPAGVPRKPGMNRDDLFNTNASI 474
           + A KDADV ++    PR PGM R DL   N  I
Sbjct: 77  AVAFKDADVALLVGARPRGPGMERKDLLTANGQI 110


>UniRef50_Q81XJ7 Cluster: L-lactate dehydrogenase 3; n=13;
           Firmicutes|Rep: L-lactate dehydrogenase 3 - Bacillus
           anthracis
          Length = 316

 Score = 36.3 bits (80), Expect = 0.83
 Identities = 26/73 (35%), Positives = 36/73 (49%), Gaps = 4/73 (5%)
 Frame = +1

Query: 301 GVAADLSHM----NTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMNRDDLFNTNA 468
           G A DLSH     NT  KV  + G  E     KD D+V+I AG   KPG +R D    +A
Sbjct: 45  GEAMDLSHCINFTNTRTKV--YAGSYE---DCKDMDIVIITAGPAPKPGQSRLDTLGASA 99

Query: 469 SIVRDIALSIAQN 507
            I+  +   + ++
Sbjct: 100 KIMESVVGGVMES 112


>UniRef50_Q608X6 Cluster: Hydrophobe/amphiphile Efflux-1 (HAE1)
           family protein; n=17; Proteobacteria|Rep:
           Hydrophobe/amphiphile Efflux-1 (HAE1) family protein -
           Methylococcus capsulatus
          Length = 1054

 Score = 35.9 bits (79), Expect = 1.1
 Identities = 20/62 (32%), Positives = 32/62 (51%)
 Frame = -2

Query: 410 GMTTTSASLMAADSSSGPLWPLTLAGVFMWERSAATPGVTGAMSYKASLVTRDSASVEGP 231
           G+T   AS+ A    +GP+  +TL    ++  SA  PG+TG M  + +LV   +A +   
Sbjct: 436 GLTPKEASIKAMSEMTGPVIGITLVLTAVFLPSAFLPGITGQMFRQFALVIASTAIISAI 495

Query: 230 KA 225
            A
Sbjct: 496 NA 497


>UniRef50_A4A2L6 Cluster: L-lactate dehydrogenase; n=4;
           Bacteria|Rep: L-lactate dehydrogenase - Blastopirellula
           marina DSM 3645
          Length = 313

 Score = 35.9 bits (79), Expect = 1.1
 Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
 Frame = +1

Query: 256 LVTRLALYDI-APVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKP 432
           +   +AL D+ A +  G A DL H   P+ V+           I D+DV+ I AG+ RKP
Sbjct: 25  IAREIALLDLNADLAGGHALDLLH-GAPS-VADQVITSGGYEHIPDSDVICITAGLRRKP 82

Query: 433 GMNRDDLFNTNASIVRDIALSI 498
             +R DL N N  +   I  S+
Sbjct: 83  DESRLDLINRNVDLFLSILDSV 104


>UniRef50_A3JXA9 Cluster: L-lactate dehydrogenase; n=1; Sagittula
           stellata E-37|Rep: L-lactate dehydrogenase - Sagittula
           stellata E-37
          Length = 300

 Score = 35.9 bits (79), Expect = 1.1
 Identities = 24/72 (33%), Positives = 38/72 (52%), Gaps = 3/72 (4%)
 Frame = +1

Query: 307 AADLSHMNTPAKVSGH---KGPEELSAAIKDADVVVIPAGVPRKPGMNRDDLFNTNASIV 477
           A D++H   P  VS      G ++LS A    DVV++  GV +KPG +R +L + NA + 
Sbjct: 33  AEDIAHA-VPFSVSARIVAGGYDDLSGA----DVVILACGVSQKPGESRLELLSRNAEVF 87

Query: 478 RDIALSIAQNDP 513
           R +   + +  P
Sbjct: 88  RAVVGDVTRAAP 99


>UniRef50_A2SSY4 Cluster: L-lactate dehydrogenase; n=3;
           Methanomicrobiales|Rep: L-lactate dehydrogenase -
           Methanocorpusculum labreanum (strain ATCC 43576 / DSM
           4855 / Z)
          Length = 319

 Score = 35.1 bits (77), Expect = 1.9
 Identities = 16/47 (34%), Positives = 28/47 (59%)
 Frame = +1

Query: 382 IKDADVVVIPAGVPRKPGMNRDDLFNTNASIVRDIALSIAQNDPKLL 522
           ++ +D++V+ +GVPRK    R DL   NA IV+  A  + +  P+ +
Sbjct: 71  LRGSDIIVLTSGVPRKATQTRLDLALENARIVKVFAEQVGRMAPEAI 117


>UniRef50_P19869 Cluster: L-lactate dehydrogenase 2; n=17;
           Bacteria|Rep: L-lactate dehydrogenase 2 -
           Bifidobacterium longum
          Length = 320

 Score = 35.1 bits (77), Expect = 1.9
 Identities = 16/47 (34%), Positives = 29/47 (61%)
 Frame = +1

Query: 385 KDADVVVIPAGVPRKPGMNRDDLFNTNASIVRDIALSIAQNDPKLLW 525
           +DAD+VVI AG  +KPG +R +L     +I++ I  ++ +  P  ++
Sbjct: 75  RDADMVVITAGPRQKPGQSRLELVGATVNILKAIMPNLVKVAPNAIY 121


>UniRef50_A1HSK3 Cluster: Lactate/malate dehydrogenase; n=1;
           Thermosinus carboxydivorans Nor1|Rep: Lactate/malate
           dehydrogenase - Thermosinus carboxydivorans Nor1
          Length = 303

 Score = 34.7 bits (76), Expect = 2.5
 Identities = 16/44 (36%), Positives = 24/44 (54%)
 Frame = +1

Query: 391 ADVVVIPAGVPRKPGMNRDDLFNTNASIVRDIALSIAQNDPKLL 522
           AD+VVI AG+PRK    R  L + NA+++ D+        P  +
Sbjct: 68  ADIVVITAGIPRKADEPRVLLLSRNAALIADLVRQAVHYSPNCI 111


>UniRef50_A1W9K7 Cluster: Malate dehydrogenase; n=95; cellular
           organisms|Rep: Malate dehydrogenase - Acidovorax sp.
           (strain JS42)
          Length = 328

 Score = 34.7 bits (76), Expect = 2.5
 Identities = 20/58 (34%), Positives = 27/58 (46%)
 Frame = +1

Query: 301 GVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMNRDDLFNTNASI 474
           GV  +L     P  ++G +   +   A KD D  ++    PR PGM R DL   NA I
Sbjct: 55  GVIMELEDCAFPL-LAGIEAHSDPMTAFKDTDYALLVGARPRGPGMERADLLAANAQI 111


>UniRef50_O61865 Cluster: Putative uncharacterized protein; n=9;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 488

 Score = 34.3 bits (75), Expect = 3.4
 Identities = 16/38 (42%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
 Frame = -1

Query: 147 FCTARAAGFRARENIFVVC-LTCIYVYI*TIST*PSRP 37
           FC+ R   F  R  +F+ C LTC+Y  +  IST P+ P
Sbjct: 320 FCSKRIKNFGMRPTMFIGCFLTCLYCALVVISTPPTAP 357


>UniRef50_Q7UY63 Cluster: L-lactate/malate dehydrogenase; n=2;
           Planctomycetaceae|Rep: L-lactate/malate dehydrogenase -
           Rhodopirellula baltica
          Length = 304

 Score = 33.9 bits (74), Expect = 4.4
 Identities = 17/40 (42%), Positives = 27/40 (67%)
 Frame = +3

Query: 510 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTL 629
           P AIV +++NPV++   +A E ++  G +DP RV+G  TL
Sbjct: 110 PNAIVVMVSNPVDA---LAYETIRLTG-FDPKRVIGTGTL 145


>UniRef50_Q4QAY8 Cluster: Putative uncharacterized protein; n=3;
           Leishmania|Rep: Putative uncharacterized protein -
           Leishmania major
          Length = 468

 Score = 33.5 bits (73), Expect = 5.9
 Identities = 32/106 (30%), Positives = 47/106 (44%)
 Frame = -2

Query: 638 DYVQSGDAEHAVRVVHSRLLEHFRGNRHCRVNRVCDDGHNSFGSF*AMDKAMSRTMEALV 459
           D   S  A  A  V+H RL E    +RH R N       +    +  +   +   +EA  
Sbjct: 259 DRASSAAAPMAGGVMHQRLAE--TNHRHNRANAASVVERDDRDPWSTLH--LRAVLEADN 314

Query: 458 LNRSSRFIPGLRGTPAGMTTTSASLMAADSSSGPLWPLTLAGVFMW 321
           ++ S  F+ G   T A + T++AS     SSS P WP T + V +W
Sbjct: 315 IDES--FLMGDTWTLA-LDTSAASTSTLTSSSAPSWPCTASTVALW 357


>UniRef50_A2E124 Cluster: Malate dehydrogenase; n=6;
           Trichomonadidae|Rep: Malate dehydrogenase - Trichomonas
           vaginalis G3
          Length = 332

 Score = 33.5 bits (73), Expect = 5.9
 Identities = 15/39 (38%), Positives = 19/39 (48%)
 Frame = +1

Query: 358 GPEELSAAIKDADVVVIPAGVPRKPGMNRDDLFNTNASI 474
           G  +L  A +D DV  +    P+KP     D F  NASI
Sbjct: 69  GTSDLEEAFRDVDVAFLVGSFPKKPSTKLVDYFQRNASI 107


>UniRef50_A2R2H9 Cluster: Similarity: the similarities are due to
           repetetive sequences. precursor; n=1; Aspergillus
           niger|Rep: Similarity: the similarities are due to
           repetetive sequences. precursor - Aspergillus niger
          Length = 994

 Score = 33.5 bits (73), Expect = 5.9
 Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 1/73 (1%)
 Frame = -2

Query: 449 SSRFIPGLRGTPAGMTTTSASL-MAADSSSGPLWPLTLAGVFMWERSAATPGVTGAMSYK 273
           S   +PGL GT +G +  S+ + +   ++S  L P   +G       A+TP V+G +   
Sbjct: 452 SVNIVPGLLGTSSGASLESSGISLGISATSTALIPGASSGTQSSAAGASTPVVSGGIIIM 511

Query: 272 ASLVTRDSASVEG 234
            +     SASV G
Sbjct: 512 PTSTESASASVSG 524


>UniRef50_UPI000023EEAF Cluster: hypothetical protein FG02077.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG02077.1 - Gibberella zeae PH-1
          Length = 184

 Score = 33.1 bits (72), Expect = 7.8
 Identities = 18/49 (36%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
 Frame = +1

Query: 238 STEAESL-VTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAA 381
           +T AE +  T  A   +AP+ P  AA+    +TPA  +  KGPE+ + A
Sbjct: 117 TTSAEVVETTAAATTTVAPIIPTTAAEEPATSTPAAATPTKGPEQANGA 165


>UniRef50_Q0UU66 Cluster: Predicted protein; n=1; Phaeosphaeria
           nodorum|Rep: Predicted protein - Phaeosphaeria nodorum
           (Septoria nodorum)
          Length = 179

 Score = 33.1 bits (72), Expect = 7.8
 Identities = 24/85 (28%), Positives = 34/85 (40%), Gaps = 1/85 (1%)
 Frame = -2

Query: 536 CDDGHNSFGSF*AMDKAMSRTMEALVLNRSSRFIPGLRGTPAGM-TTTSASLMAADSSSG 360
           CD G  S  +  A  K +   + +L  +  ++F PG     A   ++  A   AA  S+ 
Sbjct: 76  CDQGDGSAAAATAYAKCVDGCINSLFPSSQTQFAPGAAAPAASQASSVKAGASAATGSAN 135

Query: 359 PLWPLTLAGVFMWERSAATPGVTGA 285
           P  P     V     S A P  TGA
Sbjct: 136 PTGPAATGSV---SGSGAAPASTGA 157


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 758,346,763
Number of Sequences: 1657284
Number of extensions: 16417882
Number of successful extensions: 50308
Number of sequences better than 10.0: 111
Number of HSP's better than 10.0 without gapping: 47513
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 50233
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 63792713725
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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