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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= NV021185
         (765 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

DQ402957-1|ABD77290.1|  305|Homo sapiens mitochondrial malate de...   115   2e-25
CR536548-1|CAG38785.1|  338|Homo sapiens MDH2 protein.                115   2e-25
BC001917-1|AAH01917.1|  338|Homo sapiens malate dehydrogenase 2,...   115   2e-25
AF047470-1|AAC03787.1|  338|Homo sapiens malate dehydrogenase pr...   115   2e-25
AC005077-1|AAS07425.1|  316|Homo sapiens unknown protein.             115   2e-25
BC008735-1|AAH08735.2|  627|Homo sapiens FBXL10 protein protein.       33   1.5  
AK027692-1|BAB55301.1|  653|Homo sapiens protein ( Homo sapiens ...    33   1.5  
AK027440-1|BAB55112.1|  704|Homo sapiens protein ( Homo sapiens ...    33   1.5  
AJ459424-1|CAD30700.1| 1336|Homo sapiens JEMMA protein protein.        33   1.5  
AB031230-1|BAA97672.1|  827|Homo sapiens protein containing CXXC...    33   1.5  
BC007212-1|AAH07212.1|  395|Homo sapiens zinc finger protein 659...    32   2.6  
AK026072-1|BAB15350.1|  395|Homo sapiens protein ( Homo sapiens ...    32   2.6  
BC128245-1|AAI28246.1|  207|Homo sapiens C21orf67 protein protein.     31   4.5  
BC128244-1|AAI28245.1|  207|Homo sapiens C21orf67 protein protein.     31   4.5  
AF380178-1|AAL34496.1|  204|Homo sapiens C21orf67 protein protein.     31   4.5  

>DQ402957-1|ABD77290.1|  305|Homo sapiens mitochondrial malate
           dehydrogenase 2, NAD protein.
          Length = 305

 Score =  115 bits (277), Expect = 2e-25
 Identities = 57/89 (64%), Positives = 68/89 (76%)
 Frame = +1

Query: 256 LVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPG 435
           LV+RL LYDIA  TPGVAADLSH+ T A V G+ GPE+L   +K  DVVVIPAGVPRKPG
Sbjct: 28  LVSRLTLYDIAH-TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPG 86

Query: 436 MNRDDLFNTNASIVRDIALSIAQNDPKLL 522
           M RDDLFNTNA+IV  +  + AQ+ P+ +
Sbjct: 87  MTRDDLFNTNATIVATLTAACAQHCPEAM 115



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 27/43 (62%), Positives = 37/43 (86%)
 Frame = +3

Query: 510 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVV 638
           P+A++ +I NPVNST+PI +EV KK GVY+PN++ GVTTLD+V
Sbjct: 112 PEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIV 154



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 24/36 (66%), Positives = 29/36 (80%)
 Frame = +2

Query: 647 TFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQP 754
           TFV E+ G+DP  V VPVIGGH+G TIIP++SQC P
Sbjct: 158 TFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTP 193


>CR536548-1|CAG38785.1|  338|Homo sapiens MDH2 protein.
          Length = 338

 Score =  115 bits (277), Expect = 2e-25
 Identities = 57/89 (64%), Positives = 68/89 (76%)
 Frame = +1

Query: 256 LVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPG 435
           LV+RL LYDIA  TPGVAADLSH+ T A V G+ GPE+L   +K  DVVVIPAGVPRKPG
Sbjct: 49  LVSRLTLYDIAH-TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPG 107

Query: 436 MNRDDLFNTNASIVRDIALSIAQNDPKLL 522
           M RDDLFNTNA+IV  +  + AQ+ P+ +
Sbjct: 108 MTRDDLFNTNATIVATLTAACAQHCPEAM 136



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 27/43 (62%), Positives = 37/43 (86%)
 Frame = +3

Query: 510 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVV 638
           P+A++ +I NPVNST+PI +EV KK GVY+PN++ GVTTLD+V
Sbjct: 133 PEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIV 175



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 24/36 (66%), Positives = 29/36 (80%)
 Frame = +2

Query: 647 TFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQP 754
           TFV E+ G+DP  V VPVIGGH+G TIIP++SQC P
Sbjct: 179 TFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTP 214



 Score = 35.5 bits (78), Expect = 0.21
 Identities = 19/50 (38%), Positives = 30/50 (60%)
 Frame = +2

Query: 104 MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQN 253
           M S  ++P + A++   ++FST++Q N K         IGQPL+LLLK +
Sbjct: 1   MLSALVRPVSAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNS 47


>BC001917-1|AAH01917.1|  338|Homo sapiens malate dehydrogenase 2,
           NAD (mitochondrial) protein.
          Length = 338

 Score =  115 bits (277), Expect = 2e-25
 Identities = 57/89 (64%), Positives = 68/89 (76%)
 Frame = +1

Query: 256 LVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPG 435
           LV+RL LYDIA  TPGVAADLSH+ T A V G+ GPE+L   +K  DVVVIPAGVPRKPG
Sbjct: 49  LVSRLTLYDIAH-TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPG 107

Query: 436 MNRDDLFNTNASIVRDIALSIAQNDPKLL 522
           M RDDLFNTNA+IV  +  + AQ+ P+ +
Sbjct: 108 MTRDDLFNTNATIVATLTAACAQHCPEAM 136



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 27/43 (62%), Positives = 37/43 (86%)
 Frame = +3

Query: 510 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVV 638
           P+A++ +I NPVNST+PI +EV KK GVY+PN++ GVTTLD+V
Sbjct: 133 PEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIV 175



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 24/36 (66%), Positives = 29/36 (80%)
 Frame = +2

Query: 647 TFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQP 754
           TFV E+ G+DP  V VPVIGGH+G TIIP++SQC P
Sbjct: 179 TFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTP 214



 Score = 34.7 bits (76), Expect = 0.37
 Identities = 19/50 (38%), Positives = 29/50 (58%)
 Frame = +2

Query: 104 MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQN 253
           M S   +P + A++   ++FST++Q N K         IGQPL+LLLK +
Sbjct: 1   MLSALARPVSAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNS 47


>AF047470-1|AAC03787.1|  338|Homo sapiens malate dehydrogenase
           precursor protein.
          Length = 338

 Score =  115 bits (277), Expect = 2e-25
 Identities = 57/89 (64%), Positives = 68/89 (76%)
 Frame = +1

Query: 256 LVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPG 435
           LV+RL LYDIA  TPGVAADLSH+ T A V G+ GPE+L   +K  DVVVIPAGVPRKPG
Sbjct: 49  LVSRLTLYDIAH-TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPG 107

Query: 436 MNRDDLFNTNASIVRDIALSIAQNDPKLL 522
           M RDDLFNTNA+IV  +  + AQ+ P+ +
Sbjct: 108 MTRDDLFNTNATIVATLTAACAQHCPEAM 136



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 27/43 (62%), Positives = 37/43 (86%)
 Frame = +3

Query: 510 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVV 638
           P+A++ +I NPVNST+PI +EV KK GVY+PN++ GVTTLD+V
Sbjct: 133 PEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIV 175



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 24/36 (66%), Positives = 29/36 (80%)
 Frame = +2

Query: 647 TFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQP 754
           TFV E+ G+DP  V VPVIGGH+G TIIP++SQC P
Sbjct: 179 TFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTP 214



 Score = 34.7 bits (76), Expect = 0.37
 Identities = 19/50 (38%), Positives = 29/50 (58%)
 Frame = +2

Query: 104 MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQN 253
           M S   +P + A++   ++FST++Q N K         IGQPL+LLLK +
Sbjct: 1   MLSALARPVSAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNS 47


>AC005077-1|AAS07425.1|  316|Homo sapiens unknown protein.
          Length = 316

 Score =  115 bits (277), Expect = 2e-25
 Identities = 57/89 (64%), Positives = 68/89 (76%)
 Frame = +1

Query: 256 LVTRLALYDIAPVTPGVAADLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPG 435
           LV+RL LYDIA  TPGVAADLSH+ T A V G+ GPE+L   +K  DVVVIPAGVPRKPG
Sbjct: 27  LVSRLTLYDIAH-TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPG 85

Query: 436 MNRDDLFNTNASIVRDIALSIAQNDPKLL 522
           M RDDLFNTNA+IV  +  + AQ+ P+ +
Sbjct: 86  MTRDDLFNTNATIVATLTAACAQHCPEAM 114



 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 27/43 (62%), Positives = 37/43 (86%)
 Frame = +3

Query: 510 PKAIVAIITNPVNSTVPIASEVLKKAGVYDPNRVLGVTTLDVV 638
           P+A++ +I NPVNST+PI +EV KK GVY+PN++ GVTTLD+V
Sbjct: 111 PEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIV 153



 Score = 58.0 bits (134), Expect = 3e-08
 Identities = 24/36 (66%), Positives = 29/36 (80%)
 Frame = +2

Query: 647 TFVGEINGVDPTSVAVPVIGGHSGITIIPILSQCQP 754
           TFV E+ G+DP  V VPVIGGH+G TIIP++SQC P
Sbjct: 157 TFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTP 192


>BC008735-1|AAH08735.2|  627|Homo sapiens FBXL10 protein protein.
          Length = 627

 Score = 32.7 bits (71), Expect = 1.5
 Identities = 14/22 (63%), Positives = 16/22 (72%)
 Frame = -2

Query: 200 RPPL*SSSVMWWKSSLHHFVQQ 135
           RPPL SS   WW+SSL +F QQ
Sbjct: 125 RPPLGSSLSPWWRSSLTYFQQQ 146


>AK027692-1|BAB55301.1|  653|Homo sapiens protein ( Homo sapiens
           cDNA FLJ14786 fis, clone NT2RP4000737, moderately
           similar to Mus musculus F-box protein FBL10 mRNA. ).
          Length = 653

 Score = 32.7 bits (71), Expect = 1.5
 Identities = 14/22 (63%), Positives = 16/22 (72%)
 Frame = -2

Query: 200 RPPL*SSSVMWWKSSLHHFVQQ 135
           RPPL SS   WW+SSL +F QQ
Sbjct: 151 RPPLGSSLSPWWRSSLTYFQQQ 172


>AK027440-1|BAB55112.1|  704|Homo sapiens protein ( Homo sapiens
           cDNA FLJ14534 fis, clone NT2RM2000599, weakly similar to
           Homo sapiens F-box protein Lilina (LILINA) mRNA. ).
          Length = 704

 Score = 32.7 bits (71), Expect = 1.5
 Identities = 14/22 (63%), Positives = 16/22 (72%)
 Frame = -2

Query: 200 RPPL*SSSVMWWKSSLHHFVQQ 135
           RPPL SS   WW+SSL +F QQ
Sbjct: 202 RPPLGSSLSPWWRSSLTYFQQQ 223


>AJ459424-1|CAD30700.1| 1336|Homo sapiens JEMMA protein protein.
          Length = 1336

 Score = 32.7 bits (71), Expect = 1.5
 Identities = 14/22 (63%), Positives = 16/22 (72%)
 Frame = -2

Query: 200 RPPL*SSSVMWWKSSLHHFVQQ 135
           RPPL SS   WW+SSL +F QQ
Sbjct: 834 RPPLGSSLSPWWRSSLTYFQQQ 855


>AB031230-1|BAA97672.1|  827|Homo sapiens protein containing CXXC
           domain 2 protein.
          Length = 827

 Score = 32.7 bits (71), Expect = 1.5
 Identities = 14/22 (63%), Positives = 16/22 (72%)
 Frame = -2

Query: 200 RPPL*SSSVMWWKSSLHHFVQQ 135
           RPPL SS   WW+SSL +F QQ
Sbjct: 358 RPPLGSSLSPWWRSSLTYFQQQ 379


>BC007212-1|AAH07212.1|  395|Homo sapiens zinc finger protein 659
           protein.
          Length = 395

 Score = 31.9 bits (69), Expect = 2.6
 Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 2/71 (2%)
 Frame = -2

Query: 590 SRLLEHFRGNRHCRVNRVCDDGHNSFGSF*AMDKAMSR--TMEALVLNRSSRFIPGLRGT 417
           S+   H++G +H +  +  +   N   S  A D A +   ++    +N SS    G  GT
Sbjct: 93  SQAAAHYKGTKHAKKLKALEAMKNKQKSVTAKDSAKTTFTSITTNTINTSSDKTDGTAGT 152

Query: 416 PAGMTTTSASL 384
           PA  TTT+  +
Sbjct: 153 PAISTTTTVEI 163


>AK026072-1|BAB15350.1|  395|Homo sapiens protein ( Homo sapiens
           cDNA: FLJ22419 fis, clone HRC08593. ).
          Length = 395

 Score = 31.9 bits (69), Expect = 2.6
 Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 2/71 (2%)
 Frame = -2

Query: 590 SRLLEHFRGNRHCRVNRVCDDGHNSFGSF*AMDKAMSR--TMEALVLNRSSRFIPGLRGT 417
           S+   H++G +H +  +  +   N   S  A D A +   ++    +N SS    G  GT
Sbjct: 93  SQAAAHYKGTKHAKKLKALEAMKNKQKSVTAKDSAKTTFTSITTNTINTSSDKTDGTAGT 152

Query: 416 PAGMTTTSASL 384
           PA  TTT+  +
Sbjct: 153 PAISTTTTVEI 163


>BC128245-1|AAI28246.1|  207|Homo sapiens C21orf67 protein protein.
          Length = 207

 Score = 31.1 bits (67), Expect = 4.5
 Identities = 26/78 (33%), Positives = 34/78 (43%)
 Frame = -2

Query: 431 GLRGTPAGMTTTSASLMAADSSSGPLWPLTLAGVFMWERSAATPGVTGAMSYKASLVTRD 252
           G R  PAG  TT      A ++  P     LAG        A PG  GA +++  L+ R 
Sbjct: 55  GTREDPAGQETT------AITNPSPSLAADLAG-------DALPGCLGAAAHQGPLLDRS 101

Query: 251 SASVEGPKAGRYHRRHQR 198
           S S  GP+A      H+R
Sbjct: 102 SESTLGPQALELEHCHER 119


>BC128244-1|AAI28245.1|  207|Homo sapiens C21orf67 protein protein.
          Length = 207

 Score = 31.1 bits (67), Expect = 4.5
 Identities = 26/78 (33%), Positives = 34/78 (43%)
 Frame = -2

Query: 431 GLRGTPAGMTTTSASLMAADSSSGPLWPLTLAGVFMWERSAATPGVTGAMSYKASLVTRD 252
           G R  PAG  TT      A ++  P     LAG        A PG  GA +++  L+ R 
Sbjct: 55  GTREDPAGQETT------AITNPSPSLAADLAG-------DALPGCLGAAAHQGPLLDRS 101

Query: 251 SASVEGPKAGRYHRRHQR 198
           S S  GP+A      H+R
Sbjct: 102 SESTLGPQALELEHCHER 119


>AF380178-1|AAL34496.1|  204|Homo sapiens C21orf67 protein protein.
          Length = 204

 Score = 31.1 bits (67), Expect = 4.5
 Identities = 26/78 (33%), Positives = 34/78 (43%)
 Frame = -2

Query: 431 GLRGTPAGMTTTSASLMAADSSSGPLWPLTLAGVFMWERSAATPGVTGAMSYKASLVTRD 252
           G R  PAG  TT      A ++  P     LAG        A PG  GA +++  L+ R 
Sbjct: 52  GTREDPAGQETT------AITNPSPSLAADLAG-------DALPGCLGAAAHQGPLLDRS 98

Query: 251 SASVEGPKAGRYHRRHQR 198
           S S  GP+A      H+R
Sbjct: 99  SESTLGPQALELEHCHER 116


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 111,515,561
Number of Sequences: 237096
Number of extensions: 2573027
Number of successful extensions: 6127
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 5759
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6118
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9199990470
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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