Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= NV021157
(626 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P40320 Cluster: S-adenosylmethionine synthetase; n=19; ... 172 7e-42
UniRef50_Q00266 Cluster: S-adenosylmethionine synthetase isoform... 149 7e-35
UniRef50_Q8MU02 Cluster: Putative S-adenosylmethionine synthetas... 138 1e-31
UniRef50_P19358 Cluster: S-adenosylmethionine synthetase 2; n=65... 132 9e-30
UniRef50_Q29NR2 Cluster: GA15421-PA; n=3; Bilateria|Rep: GA15421... 125 8e-28
UniRef50_Q9K7Q9 Cluster: S-adenosylmethionine synthetase; n=65; ... 95 1e-18
UniRef50_A7NSM8 Cluster: Chromosome chr18 scaffold_1, whole geno... 93 5e-18
UniRef50_Q837P9 Cluster: S-adenosylmethionine synthetase; n=45; ... 93 7e-18
UniRef50_A7APP7 Cluster: S-adenosylmethionine synthetase, putati... 90 3e-17
UniRef50_P0A820 Cluster: S-adenosylmethionine synthetase; n=23; ... 89 6e-17
UniRef50_P72871 Cluster: S-adenosylmethionine synthetase; n=119;... 84 2e-15
UniRef50_Q2U8T6 Cluster: S-adenosylmethionine synthetase; n=2; A... 73 4e-12
UniRef50_Q650L4 Cluster: S-adenosylmethionine synthetase; n=19; ... 73 4e-12
UniRef50_Q4A5F4 Cluster: S-adenosylmethionine synthetase; n=4; B... 72 1e-11
UniRef50_Q661P3 Cluster: S-adenosylmethionine synthetase; n=3; B... 71 2e-11
UniRef50_A4QEH8 Cluster: Putative uncharacterized protein; n=1; ... 70 5e-11
UniRef50_Q1GND0 Cluster: S-adenosylmethionine synthetase; n=29; ... 69 7e-11
UniRef50_Q7QWJ4 Cluster: S-adenosylmethionine synthetase; n=1; G... 68 2e-10
UniRef50_Q6KHY1 Cluster: S-adenosylmethionine synthetase; n=7; M... 65 1e-09
UniRef50_Q7NB16 Cluster: S-adenosylmethionine synthetase; n=2; M... 64 3e-09
UniRef50_A6BGC6 Cluster: S-adenosylmethionine synthetase; n=1; D... 62 1e-08
UniRef50_Q60BL6 Cluster: S-adenosylmethionine synthetase; n=6; B... 60 3e-08
UniRef50_Q2GDS4 Cluster: S-adenosylmethionine synthetase; n=1; N... 58 2e-07
UniRef50_Q2LSR0 Cluster: S-adenosylmethionine synthetase; n=1; S... 57 4e-07
UniRef50_Q6SZ22 Cluster: S-adenosylmethionine synthetase; n=4; S... 56 5e-07
UniRef50_A6QA94 Cluster: S-adenosylmethionine synthetase; n=20; ... 56 5e-07
UniRef50_P78003 Cluster: S-adenosylmethionine synthetase; n=4; M... 56 5e-07
UniRef50_O09486 Cluster: S-adenosylmethionine synthetase; n=1; A... 56 5e-07
UniRef50_Q5FGR4 Cluster: S-adenosylmethionine synthetase; n=13; ... 54 3e-06
UniRef50_UPI00015BD1C2 Cluster: UPI00015BD1C2 related cluster; n... 54 4e-06
UniRef50_A6PKG8 Cluster: Methionine adenosyltransferase precurso... 47 4e-04
UniRef50_Q7R6Z1 Cluster: Putative uncharacterized protein PY0779... 46 6e-04
UniRef50_Q6A7D8 Cluster: S-adenosylmethionine synthetase; n=11; ... 45 0.001
UniRef50_Q1VNA9 Cluster: S-adenosylmethionine synthetase; n=1; P... 45 0.002
UniRef50_Q95QX7 Cluster: Putative uncharacterized protein; n=1; ... 44 0.002
UniRef50_Q027Y1 Cluster: Methionine adenosyltransferase; n=1; So... 38 0.20
UniRef50_A4DEX8 Cluster: Putative uncharacterized protein; n=1; ... 38 0.20
UniRef50_UPI0000ECA413 Cluster: Endothelial cell-selective adhes... 36 1.1
UniRef50_Q8FXU7 Cluster: Protease, putative; n=6; Brucellaceae|R... 35 1.4
UniRef50_Q8ETA1 Cluster: Hypothetical conserved protein; n=1; Oc... 35 1.4
UniRef50_A6RT45 Cluster: Putative uncharacterized protein; n=2; ... 34 2.4
UniRef50_Q15TP8 Cluster: Adenosine deaminase; n=2; Gammaproteoba... 34 3.2
UniRef50_Q4QGM3 Cluster: Putative uncharacterized protein; n=3; ... 34 3.2
UniRef50_A4A0G4 Cluster: DNA-binding protein; n=1; Blastopirellu... 33 4.2
UniRef50_A7SQA7 Cluster: Predicted protein; n=1; Nematostella ve... 33 4.2
UniRef50_Q7QFB7 Cluster: ENSANGP00000022002; n=1; Anopheles gamb... 33 5.6
UniRef50_UPI0000498BC3 Cluster: conserved hypothetical protein; ... 33 7.4
UniRef50_UPI00006A2011 Cluster: Tumor necrosis factor receptor s... 33 7.4
UniRef50_A7MES0 Cluster: Putative uncharacterized protein; n=1; ... 33 7.4
UniRef50_A0NE72 Cluster: ENSANGP00000030279; n=1; Anopheles gamb... 33 7.4
UniRef50_Q4SDE4 Cluster: Chromosome 3 SCAF14639, whole genome sh... 32 9.8
>UniRef50_P40320 Cluster: S-adenosylmethionine synthetase; n=19;
Eukaryota|Rep: S-adenosylmethionine synthetase -
Drosophila melanogaster (Fruit fly)
Length = 408
Score = 172 bits (418), Expect = 7e-42
Identities = 83/123 (67%), Positives = 97/123 (78%), Gaps = 1/123 (0%)
Frame = +1
Query: 259 KTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAG 438
KTGM+LLCGEITSKA VDYQKVVRETV+HIGYDDSSKGFD+KTC+V+LALDQQSP IAAG
Sbjct: 72 KTGMILLCGEITSKAVVDYQKVVRETVQHIGYDDSSKGFDFKTCNVLLALDQQSPEIAAG 131
Query: 439 VHENRNDEEVGARDQGLMFGYATVRQKNACR*L*CLHTNSI-RKLQSSGEMENFWWARPD 615
VH NR +EE+GA DQG+MFGYAT + C L + + + K+ + FWWARPD
Sbjct: 132 VHVNRAEEEIGAGDQGIMFGYAT-DETEECMPLTVVLAHKLNEKIAELRRSDVFWWARPD 190
Query: 616 SKT 624
SKT
Sbjct: 191 SKT 193
Score = 113 bits (271), Expect = 4e-24
Identities = 51/62 (82%), Positives = 55/62 (88%)
Frame = +2
Query: 77 NGYAKTNGHSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETK 256
NG +NG+SYDMEDG+ FLFTSESVGEGHPDKMCDQISDAILDAHL QDP+AKVACET
Sbjct: 11 NGCNGSNGNSYDMEDGATFLFTSESVGEGHPDKMCDQISDAILDAHLKQDPNAKVACETV 70
Query: 257 LK 262
K
Sbjct: 71 AK 72
>UniRef50_Q00266 Cluster: S-adenosylmethionine synthetase isoform
type-1; n=171; cellular organisms|Rep:
S-adenosylmethionine synthetase isoform type-1 - Homo
sapiens (Human)
Length = 395
Score = 149 bits (360), Expect = 7e-35
Identities = 73/123 (59%), Positives = 91/123 (73%), Gaps = 1/123 (0%)
Frame = +1
Query: 259 KTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAG 438
KTGMVLLCGEITS A VDYQ+VVR+T+KHIGYDDS+KGFD+KTC+V++AL+QQSP+IA
Sbjct: 61 KTGMVLLCGEITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQC 120
Query: 439 VHENRNDEEVGARDQGLMFGYATVRQKNACR*L*CLHTNSIRKLQSSGEMENFW-WARPD 615
VH +RN+E+VGA DQGLMFGYAT + C L + + + + W RPD
Sbjct: 121 VHLDRNEEDVGAGDQGLMFGYAT-DETEECMPLTIILAHKLNARMADLRRSGLLPWLRPD 179
Query: 616 SKT 624
SKT
Sbjct: 180 SKT 182
Score = 88.2 bits (209), Expect = 1e-16
Identities = 39/52 (75%), Positives = 46/52 (88%)
Frame = +2
Query: 107 YDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKLK 262
+ + +G VF+FTSESVGEGHPDK+CDQISDA+LDAHL QDP+AKVACET K
Sbjct: 11 HSLSEG-VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCK 61
>UniRef50_Q8MU02 Cluster: Putative S-adenosylmethionine synthetase;
n=1; Heterodera glycines|Rep: Putative
S-adenosylmethionine synthetase - Heterodera glycines
(Soybean cyst nematode worm)
Length = 211
Score = 138 bits (334), Expect = 1e-31
Identities = 61/82 (74%), Positives = 73/82 (89%)
Frame = +1
Query: 256 TKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAA 435
TKTGMVL+CGE TS A VDYQ VVRET+K IGYDDSSKGF+YKTC+V++AL++QSP IAA
Sbjct: 97 TKTGMVLVCGETTSSATVDYQSVVRETIKKIGYDDSSKGFNYKTCNVLVALEKQSPEIAA 156
Query: 436 GVHENRNDEEVGARDQGLMFGY 501
GVHE++ E+VGARDQG+MF Y
Sbjct: 157 GVHEDKEPEDVGARDQGIMFXY 178
Score = 83.0 bits (196), Expect = 5e-15
Identities = 39/49 (79%), Positives = 39/49 (79%)
Frame = +2
Query: 116 EDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKLK 262
E FLFTSESVGEGHPDKMCDQISDAILDAHL DP AKVACE K
Sbjct: 50 EQVGTFLFTSESVGEGHPDKMCDQISDAILDAHLALDPAAKVACEVVTK 98
Score = 37.1 bits (82), Expect = 0.34
Identities = 16/26 (61%), Positives = 21/26 (80%)
Frame = +3
Query: 510 ETEECMPLTVVLAHKLNQKIAELRRN 587
E+ E MPLT+VL+HKLN K +LRR+
Sbjct: 182 ESPEAMPLTLVLSHKLNAKYHQLRRS 207
>UniRef50_P19358 Cluster: S-adenosylmethionine synthetase 2; n=659;
cellular organisms|Rep: S-adenosylmethionine synthetase
2 - Saccharomyces cerevisiae (Baker's yeast)
Length = 384
Score = 132 bits (318), Expect = 9e-30
Identities = 61/123 (49%), Positives = 89/123 (72%), Gaps = 1/123 (0%)
Frame = +1
Query: 259 KTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAG 438
KTGM+++ GEIT+KA +DYQ++VR+T+K IGYDDS+KGFDYKTC+V++A++QQSP+IA G
Sbjct: 50 KTGMIMVFGEITTKARLDYQQIVRDTIKKIGYDDSAKGFDYKTCNVLVAIEQQSPDIAQG 109
Query: 439 VHENRNDEEVGARDQGLMFGYATVRQKNACR*L*CLHTNSIRKLQSSGEME-NFWWARPD 615
+H ++ E++GA DQG+MFGYAT L L + + + + + W RPD
Sbjct: 110 LHYEKSLEDLGAGDQGIMFGYATDETPEGLP-LTILLAHKLNMAMADARRDGSLPWLRPD 168
Query: 616 SKT 624
+KT
Sbjct: 169 TKT 171
Score = 81.8 bits (193), Expect = 1e-14
Identities = 37/50 (74%), Positives = 40/50 (80%)
Frame = +2
Query: 113 MEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKLK 262
M FLFTSESVGEGHPDK+CDQ+SDAILDA L QDP +KVACET K
Sbjct: 1 MSKSKTFLFTSESVGEGHPDKICDQVSDAILDACLEQDPFSKVACETAAK 50
>UniRef50_Q29NR2 Cluster: GA15421-PA; n=3; Bilateria|Rep: GA15421-PA
- Drosophila pseudoobscura (Fruit fly)
Length = 200
Score = 125 bits (302), Expect = 8e-28
Identities = 58/83 (69%), Positives = 72/83 (86%)
Frame = +1
Query: 259 KTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAG 438
KTGM+LLCGEITSKA VDYQKVVRETV+HIGYDDSSKGFD+KT ++++A++QQSP+IA G
Sbjct: 72 KTGMILLCGEITSKAVVDYQKVVRETVQHIGYDDSSKGFDWKTLNLLVAIEQQSPDIANG 131
Query: 439 VHENRNDEEVGARDQGLMFGYAT 507
VH NR +++VGA DQ + AT
Sbjct: 132 VHINREEDDVGAGDQVSILKRAT 154
Score = 112 bits (270), Expect = 6e-24
Identities = 51/62 (82%), Positives = 54/62 (87%)
Frame = +2
Query: 77 NGYAKTNGHSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETK 256
NG +NG+SYDMEDG FLFTSESVGEGHPDKMCDQISDAILDAHL QDP+AKVACET
Sbjct: 11 NGCNGSNGNSYDMEDGQTFLFTSESVGEGHPDKMCDQISDAILDAHLKQDPNAKVACETV 70
Query: 257 LK 262
K
Sbjct: 71 AK 72
>UniRef50_Q9K7Q9 Cluster: S-adenosylmethionine synthetase; n=65;
cellular organisms|Rep: S-adenosylmethionine synthetase
- Bacillus halodurans
Length = 399
Score = 95.1 bits (226), Expect = 1e-18
Identities = 57/146 (39%), Positives = 83/146 (56%), Gaps = 10/146 (6%)
Frame = +1
Query: 217 ESGSGRKSCM*NQTKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSV 396
E + R +C + T TG+VL+ GEIT+ VD KVVR+T+++IGY + GFD +TC+V
Sbjct: 38 EDPNARVACETSVT-TGLVLVAGEITTSTYVDIPKVVRDTIRNIGYTRAKYGFDSETCAV 96
Query: 397 MLALDQQSPNIAAGVHE----------NRNDEEVGARDQGLMFGYATVRQKNACR*L*CL 546
+ ++D+QSP+IA GV++ + E +GA DQGLMFGYA L
Sbjct: 97 LTSIDEQSPDIAQGVNQALEAREGQMTDAEIEAIGAGDQGLMFGYANNETPELMPLPISL 156
Query: 547 HTNSIRKLQSSGEMENFWWARPDSKT 624
R+L + + E + RPD KT
Sbjct: 157 SHKLARRLSEARKGEILPYLRPDGKT 182
Score = 71.3 bits (167), Expect = 2e-11
Identities = 31/42 (73%), Positives = 37/42 (88%)
Frame = +2
Query: 134 LFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKL 259
LFTSESV EGHPDK+CDQISD+ILD L +DP+A+VACET +
Sbjct: 9 LFTSESVTEGHPDKICDQISDSILDEILKEDPNARVACETSV 50
>UniRef50_A7NSM8 Cluster: Chromosome chr18 scaffold_1, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr18 scaffold_1, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 509
Score = 93.1 bits (221), Expect = 5e-18
Identities = 52/123 (42%), Positives = 68/123 (55%)
Frame = +1
Query: 256 TKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAA 435
TKT MV++ GEIT+KAN+DY+K+VR+T + IG+ GFD C V++ + QQSPNI
Sbjct: 284 TKTDMVMIFGEITTKANIDYEKIVRDTCRTIGFVFYDVGFDVDNCKVLVNIGQQSPNITQ 343
Query: 436 GVHENRNDEEVGARDQGLMFGYATVRQKNACR*L*CLHTNSIRKLQSSGEMENFWWARPD 615
V + + A DQG MFGYAT L T +L + E W RPD
Sbjct: 344 DV------QGISAGDQGHMFGYATNETPKLMPLSHVLSTKLSARLTEVRKNETCSWLRPD 397
Query: 616 SKT 624
KT
Sbjct: 398 GKT 400
Score = 50.0 bits (114), Expect = 5e-05
Identities = 24/43 (55%), Positives = 29/43 (67%)
Frame = +2
Query: 134 LFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKLK 262
L+ E V GH ++ ISDA+LDA L QDPD+KVACET K
Sbjct: 243 LYYMEDVSIGHVHQIQSDISDAVLDACLTQDPDSKVACETCTK 285
>UniRef50_Q837P9 Cluster: S-adenosylmethionine synthetase; n=45;
cellular organisms|Rep: S-adenosylmethionine synthetase
- Enterococcus faecalis (Streptococcus faecalis)
Length = 394
Score = 92.7 bits (220), Expect = 7e-18
Identities = 54/127 (42%), Positives = 79/127 (62%), Gaps = 6/127 (4%)
Frame = +1
Query: 262 TGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGV 441
TG+VL+ GEI++ A VD QK+VR+TVK IGY + GFD +T +V++A+D+QSP+IA GV
Sbjct: 49 TGLVLVFGEISTTAYVDIQKIVRQTVKDIGYTRAKYGFDGETVAVLVAIDEQSPDIAQGV 108
Query: 442 H---ENRNDEE---VGARDQGLMFGYATVRQKNACR*L*CLHTNSIRKLQSSGEMENFWW 603
E R+ +E +GA DQGLMFG+A L +R+L + + +
Sbjct: 109 DAALEVRDQDEKDDIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRLAELRKEKVLPY 168
Query: 604 ARPDSKT 624
RPD+K+
Sbjct: 169 LRPDAKS 175
Score = 69.3 bits (162), Expect = 7e-11
Identities = 31/42 (73%), Positives = 36/42 (85%)
Frame = +2
Query: 134 LFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKL 259
LFTSESV EGHPDK+ DQ+SDAILDA L +DP A+VACET +
Sbjct: 6 LFTSESVSEGHPDKVADQVSDAILDAILEKDPMARVACETSV 47
>UniRef50_A7APP7 Cluster: S-adenosylmethionine synthetase, putative;
n=1; Babesia bovis|Rep: S-adenosylmethionine synthetase,
putative - Babesia bovis
Length = 416
Score = 90.2 bits (214), Expect = 3e-17
Identities = 49/119 (41%), Positives = 67/119 (56%)
Frame = +1
Query: 268 MVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVHE 447
+V++ GEIT+ A VDYQ VVR+ + IGY + GFD T +M+ L QQ+P IA+ VH
Sbjct: 60 LVMVFGEITTNAVVDYQAVVRQVLTDIGYTSNELGFDASTVEIMVRLAQQAPEIASAVHL 119
Query: 448 NRNDEEVGARDQGLMFGYATVRQKNACR*L*CLHTNSIRKLQSSGEMENFWWARPDSKT 624
R EE A DQG+MFGYA+ L T ++L + + + RPD KT
Sbjct: 120 GRKLEETAAGDQGIMFGYASDETPELMPLSHALATRLGKRLTKVRKTKVMPYLRPDGKT 178
Score = 79.0 bits (186), Expect = 9e-14
Identities = 36/47 (76%), Positives = 40/47 (85%)
Frame = +2
Query: 110 DMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 250
D D + FLFTSESV EGHPDK+CDQISDAILDA L QDP++KVACE
Sbjct: 7 DTVDKNNFLFTSESVNEGHPDKICDQISDAILDACLRQDPESKVACE 53
>UniRef50_P0A820 Cluster: S-adenosylmethionine synthetase; n=23;
Proteobacteria|Rep: S-adenosylmethionine synthetase -
Shigella flexneri
Length = 384
Score = 89.4 bits (212), Expect = 6e-17
Identities = 45/83 (54%), Positives = 59/83 (71%)
Frame = +1
Query: 259 KTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAG 438
KTGMVL+ GEIT+ A VD +++ R TV+ IGY S GFD +C+V+ A+ +QSP+I G
Sbjct: 47 KTGMVLVGGEITTSAWVDIEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPDINQG 106
Query: 439 VHENRNDEEVGARDQGLMFGYAT 507
V + + E GA DQGLMFGYAT
Sbjct: 107 V-DRADPLEQGAGDQGLMFGYAT 128
Score = 72.9 bits (171), Expect = 6e-12
Identities = 33/43 (76%), Positives = 37/43 (86%)
Frame = +2
Query: 134 LFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKLK 262
LFTSESV EGHPDK+ DQISDA+LDA L QDP A+VACET +K
Sbjct: 5 LFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVK 47
Score = 32.7 bits (71), Expect = 7.4
Identities = 15/36 (41%), Positives = 22/36 (61%)
Frame = +3
Query: 483 GLDVRLCHSETEECMPLTVVLAHKLNQKIAELRRNG 590
GL +ET+ MP + AH+L Q+ AE+R+NG
Sbjct: 121 GLMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNG 156
>UniRef50_P72871 Cluster: S-adenosylmethionine synthetase; n=119;
Bacteria|Rep: S-adenosylmethionine synthetase -
Synechocystis sp. (strain PCC 6803)
Length = 426
Score = 84.2 bits (199), Expect = 2e-15
Identities = 40/90 (44%), Positives = 64/90 (71%), Gaps = 9/90 (10%)
Frame = +1
Query: 262 TGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGV 441
TG+ L+ GEITS+A++++ +++R+ + IGY ++ G+ +C+VMLA+D+QSP+I+ GV
Sbjct: 55 TGLTLVTGEITSQAHINFVELIRQKIAEIGYTNADNGYSANSCAVMLAIDEQSPDISQGV 114
Query: 442 -------HENRNDE--EVGARDQGLMFGYA 504
H +DE ++GA DQGLMFGYA
Sbjct: 115 TAAQEQRHALSDDELDKIGAGDQGLMFGYA 144
Score = 67.3 bits (157), Expect = 3e-10
Identities = 30/41 (73%), Positives = 35/41 (85%)
Frame = +2
Query: 131 FLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACET 253
+LFTSESV EGHPDK+CDQISD ILDA L DP+++VA ET
Sbjct: 11 YLFTSESVTEGHPDKVCDQISDTILDALLTLDPNSRVAAET 51
Score = 33.5 bits (73), Expect = 4.2
Identities = 12/29 (41%), Positives = 23/29 (79%)
Frame = +3
Query: 507 SETEECMPLTVVLAHKLNQKIAELRRNGE 593
+ET E MPL + LAH++ +++E+R++G+
Sbjct: 146 NETPELMPLPISLAHRIALRLSEVRKSGQ 174
>UniRef50_Q2U8T6 Cluster: S-adenosylmethionine synthetase; n=2;
Ascomycota|Rep: S-adenosylmethionine synthetase -
Aspergillus oryzae
Length = 384
Score = 73.3 bits (172), Expect = 4e-12
Identities = 33/51 (64%), Positives = 41/51 (80%)
Frame = +2
Query: 113 MEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKLKP 265
M+ S FLFTSESVGEGHPDK+CDQ++DAILD L Q+P +KVA E ++P
Sbjct: 1 MKSQSKFLFTSESVGEGHPDKICDQVADAILDECLKQNPLSKVAIEVAVRP 51
Score = 56.4 bits (130), Expect = 5e-07
Identities = 38/124 (30%), Positives = 60/124 (48%), Gaps = 3/124 (2%)
Frame = +1
Query: 259 KTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAG 438
+ G+V++ G + +D +VR +K IGY + DY+TC VM ++ P++ G
Sbjct: 50 RPGLVIVFGVVHFIPQLDIDAIVRFVLKDIGYTSPDQELDYRTCQVMDCVELH-PSLFNG 108
Query: 439 VH---ENRNDEEVGARDQGLMFGYATVRQKNACR*L*CLHTNSIRKLQSSGEMENFWWAR 609
+ E +DE G DQG+ FGYAT L R+L+++ W R
Sbjct: 109 ISSGLEAPDDEPAG--DQGMAFGYATDETPQLLPLTLHLAHRISRELKAAHTNRILPWLR 166
Query: 610 PDSK 621
PD+K
Sbjct: 167 PDTK 170
>UniRef50_Q650L4 Cluster: S-adenosylmethionine synthetase; n=19;
cellular organisms|Rep: S-adenosylmethionine synthetase
- Bacteroides fragilis
Length = 430
Score = 73.3 bits (172), Expect = 4e-12
Identities = 37/87 (42%), Positives = 52/87 (59%)
Frame = +1
Query: 262 TGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGV 441
TG V+L GE+ + A VD Q + RE ++ IGY F+ +C V+ A+ +QS +I GV
Sbjct: 47 TGQVVLAGEVKTGAYVDLQLIAREVIQKIGYTKGEYMFESNSCGVLSAIHEQSADINRGV 106
Query: 442 HENRNDEEVGARDQGLMFGYATVRQKN 522
E + GA DQG+MFGYAT +N
Sbjct: 107 -EREDPMNQGAGDQGMMFGYATNETEN 132
Score = 67.7 bits (158), Expect = 2e-10
Identities = 30/41 (73%), Positives = 34/41 (82%)
Frame = +2
Query: 131 FLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACET 253
+LFTSESV EGHPDK+ DQISDA+LD L DP +KVACET
Sbjct: 3 YLFTSESVSEGHPDKVADQISDAVLDKLLAYDPSSKVACET 43
>UniRef50_Q4A5F4 Cluster: S-adenosylmethionine synthetase; n=4;
Bacteria|Rep: S-adenosylmethionine synthetase -
Mycoplasma synoviae (strain 53)
Length = 382
Score = 72.1 bits (169), Expect = 1e-11
Identities = 35/58 (60%), Positives = 41/58 (70%)
Frame = +2
Query: 134 LFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKLKPVWCFCVAKSHPKLT 307
LFTSESVG GHPDK+CDQISDAILDA+L DP +KVA ET + F + K+T
Sbjct: 4 LFTSESVGRGHPDKICDQISDAILDAYLTWDPHSKVAVETMVSGNNVFIAGEVKSKVT 61
Score = 54.4 bits (125), Expect = 2e-06
Identities = 30/79 (37%), Positives = 46/79 (58%)
Frame = +1
Query: 271 VLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVHEN 450
V + GE+ SK VD ++ + +++IGY ++ F + + QS NIA GV+
Sbjct: 50 VFIAGEVKSKVTVDVIEIAKNVLRNIGYYSNNTSF-------ITDIKSQSENIAMGVNLQ 102
Query: 451 RNDEEVGARDQGLMFGYAT 507
+D ++GA DQG MFGYAT
Sbjct: 103 DSD-DLGAGDQGFMFGYAT 120
>UniRef50_Q661P3 Cluster: S-adenosylmethionine synthetase; n=3;
Borrelia burgdorferi group|Rep: S-adenosylmethionine
synthetase - Borrelia garinii
Length = 392
Score = 71.3 bits (167), Expect = 2e-11
Identities = 44/124 (35%), Positives = 71/124 (57%), Gaps = 5/124 (4%)
Frame = +1
Query: 268 MVLLCGEITS--KANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGV 441
+V++ GEI S K +D +++ ++ +K IGY + G DYKT +V+ A+ QS +I +
Sbjct: 55 LVVIAGEINSPVKKTLDIKEIAKKIIKDIGYTNIDYGLDYKTITVIDAIGNQSQDIINAI 114
Query: 442 HENRNDEEVGARDQGLMFGYATVRQKNACR*L*CLHTNSIRK---LQSSGEMENFWWARP 612
+ + +GA DQG++FGYA KN L + ++K L+ SG +E W RP
Sbjct: 115 -KKKGSNALGAGDQGIIFGYACDETKNFLPAPYELANSILKKASNLRKSGAIE---WLRP 170
Query: 613 DSKT 624
DSK+
Sbjct: 171 DSKS 174
Score = 58.4 bits (135), Expect = 1e-07
Identities = 27/37 (72%), Positives = 30/37 (81%)
Frame = +2
Query: 140 TSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 250
TSE+V EGHPDK+ DQISDAILD L D +AKVACE
Sbjct: 12 TSEAVSEGHPDKIADQISDAILDEILKVDKNAKVACE 48
>UniRef50_A4QEH8 Cluster: Putative uncharacterized protein; n=1;
Corynebacterium glutamicum R|Rep: Putative
uncharacterized protein - Corynebacterium glutamicum
(strain R)
Length = 257
Score = 69.7 bits (163), Expect = 5e-11
Identities = 37/91 (40%), Positives = 54/91 (59%), Gaps = 9/91 (9%)
Frame = +1
Query: 262 TGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGV 441
TG+V + GE+ + A V+ ++VR + IG++ S GFD +TC V +++ +QS IA GV
Sbjct: 52 TGIVHVVGEVRTSAYVEIPQLVRNKLIEIGFNSSEVGFDGRTCGVSVSIGEQSQEIADGV 111
Query: 442 HEN---------RNDEEVGARDQGLMFGYAT 507
+ D+ GA DQGLMFGYAT
Sbjct: 112 DNSDEARTNGDVEEDDRAGAGDQGLMFGYAT 142
Score = 64.9 bits (151), Expect = 1e-09
Identities = 30/43 (69%), Positives = 35/43 (81%)
Frame = +2
Query: 125 SVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACET 253
+V LFTSESV EGHPDK+CD ISD ILDA L +DP ++VA ET
Sbjct: 6 AVRLFTSESVTEGHPDKICDAISDTILDALLEKDPQSRVAVET 48
Score = 37.1 bits (82), Expect = 0.34
Identities = 15/36 (41%), Positives = 25/36 (69%)
Frame = +3
Query: 483 GLDVRLCHSETEECMPLTVVLAHKLNQKIAELRRNG 590
GL +ETEE MPL + LAH+L++++ ++R+ G
Sbjct: 135 GLMFGYATNETEEYMPLPIALAHRLSRRLTQVRKEG 170
>UniRef50_Q1GND0 Cluster: S-adenosylmethionine synthetase; n=29;
Alphaproteobacteria|Rep: S-adenosylmethionine synthetase
- Sphingopyxis alaskensis (Sphingomonas alaskensis)
Length = 406
Score = 69.3 bits (162), Expect = 7e-11
Identities = 30/41 (73%), Positives = 36/41 (87%)
Frame = +2
Query: 131 FLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACET 253
FLFTSESV EGHPDK+ DQISD+I+D L +DP+A+VACET
Sbjct: 5 FLFTSESVSEGHPDKVADQISDSIVDLFLAKDPEARVACET 45
Score = 52.8 bits (121), Expect = 6e-06
Identities = 32/75 (42%), Positives = 41/75 (54%)
Frame = +1
Query: 283 GEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVHENRNDE 462
GE A + + VR TV+ IGY+ + GF + L QSP IA GV E +
Sbjct: 67 GEWAPGALDEIEATVRRTVREIGYEQA--GFHWNRFRFENNLHGQSPQIAQGVDEGAGKD 124
Query: 463 EVGARDQGLMFGYAT 507
E GA DQG+MFGYA+
Sbjct: 125 E-GAGDQGIMFGYAS 138
>UniRef50_Q7QWJ4 Cluster: S-adenosylmethionine synthetase; n=1;
Giardia lamblia ATCC 50803|Rep: S-adenosylmethionine
synthetase - Giardia lamblia ATCC 50803
Length = 436
Score = 67.7 bits (158), Expect = 2e-10
Identities = 42/125 (33%), Positives = 67/125 (53%), Gaps = 3/125 (2%)
Frame = +1
Query: 259 KTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAG 438
K V L GEI++ A VDY ++VR+ ++ IGY+D D++T ++ + QSP+I
Sbjct: 53 KDNTVFLLGEISTTAVVDYNQIVRDVLREIGYEDEKTSCDWRTVEIINRISSQSPDIYQA 112
Query: 439 VHENRNDEEVGARDQGLMFGYATVRQK---NACR*L*CLHTNSIRKLQSSGEMENFWWAR 609
V +E+ A DQG+M GYA+ K A L + +++ +G + + R
Sbjct: 113 VF---RQDELCAGDQGIMIGYASQETKALMPATHLFANLLAMRLSRVRKTGVLP---FLR 166
Query: 610 PDSKT 624
PDSKT
Sbjct: 167 PDSKT 171
Score = 63.3 bits (147), Expect = 5e-09
Identities = 29/44 (65%), Positives = 33/44 (75%)
Frame = +2
Query: 131 FLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKLK 262
FLFTSE V EGHPDK+CDQISD ILD L QD A+VA + +K
Sbjct: 10 FLFTSEQVSEGHPDKICDQISDRILDTILAQDKIARVAADVAIK 53
>UniRef50_Q6KHY1 Cluster: S-adenosylmethionine synthetase; n=7;
Mycoplasma|Rep: S-adenosylmethionine synthetase -
Mycoplasma mobile
Length = 386
Score = 65.3 bits (152), Expect = 1e-09
Identities = 28/39 (71%), Positives = 35/39 (89%)
Frame = +2
Query: 134 LFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 250
+FTSESVG+GHPDK+CDQISD ILD+ L +D +A+VACE
Sbjct: 5 IFTSESVGKGHPDKICDQISDRILDSILKKDCNARVACE 43
Score = 41.5 bits (93), Expect = 0.016
Identities = 23/80 (28%), Positives = 50/80 (62%)
Frame = +1
Query: 268 MVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVHE 447
++++ GEI + + +D K + +GYD++ D+ +++ +++QS +I+ GV
Sbjct: 50 LIVIGGEIKTNSYIDVVKEAWNILLKLGYDEN----DF---TIISNINKQSSDISFGV-- 100
Query: 448 NRNDEEVGARDQGLMFGYAT 507
++++ + A DQG++FGYAT
Sbjct: 101 DKSNGSIAAGDQGIVFGYAT 120
>UniRef50_Q7NB16 Cluster: S-adenosylmethionine synthetase; n=2;
Mycoplasmataceae|Rep: S-adenosylmethionine synthetase -
Mycoplasma gallisepticum
Length = 395
Score = 63.7 bits (148), Expect = 3e-09
Identities = 30/60 (50%), Positives = 41/60 (68%)
Frame = +2
Query: 71 KMNGYAKTNGHSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 250
K+ GY N ++ ++T+ESVG HPDK+CDQI+DAILDA L QD +++VACE
Sbjct: 3 KIKGYFTLN--IINLNHNRKGVYTAESVGSAHPDKLCDQIADAILDACLKQDQNSRVACE 60
Score = 52.4 bits (120), Expect = 9e-06
Identities = 30/85 (35%), Positives = 50/85 (58%)
Frame = +1
Query: 268 MVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVHE 447
++++ GEI++KA+VDY + V GYD S D+ +++ ++QQS IA V
Sbjct: 67 LIIIAGEISTKASVDYVGTAWKVVNQFGYDRS----DF---TIIANINQQSSEIAQSV-- 117
Query: 448 NRNDEEVGARDQGLMFGYATVRQKN 522
++ + ++GA DQG+ GYA KN
Sbjct: 118 DQKNHKIGAGDQGITVGYACDETKN 142
>UniRef50_A6BGC6 Cluster: S-adenosylmethionine synthetase; n=1;
Dorea longicatena DSM 13814|Rep: S-adenosylmethionine
synthetase - Dorea longicatena DSM 13814
Length = 387
Score = 62.1 bits (144), Expect = 1e-08
Identities = 26/38 (68%), Positives = 32/38 (84%)
Frame = +2
Query: 137 FTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 250
+T+ESV EGHPDK+CDQI+DAILD L DP ++VACE
Sbjct: 6 YTAESVTEGHPDKVCDQIADAILDECLRYDPSSRVACE 43
Score = 36.7 bits (81), Expect = 0.45
Identities = 34/103 (33%), Positives = 48/103 (46%), Gaps = 10/103 (9%)
Frame = +1
Query: 226 SGRKSCM*NQTKTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLA 405
S R +C T+ G V + GEITS V+R+ ++ GY + G + T
Sbjct: 37 SSRVACEVLATR-GNVFVAGEITSGYEPPVFDVIRKVLEECGY--CTDGIEMDTF----- 88
Query: 406 LDQQSPNIAAGVHENRN----------DEEVGARDQGLMFGYA 504
+ QQSP+IA V ++ D GA DQG+M GYA
Sbjct: 89 VHQQSPDIAKAVSVSKEFRDNIGAKLRDRSRGAGDQGVMVGYA 131
>UniRef50_Q60BL6 Cluster: S-adenosylmethionine synthetase; n=6;
Bacteria|Rep: S-adenosylmethionine synthetase -
Methylococcus capsulatus
Length = 397
Score = 60.5 bits (140), Expect = 3e-08
Identities = 29/53 (54%), Positives = 35/53 (66%)
Frame = +2
Query: 131 FLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKLKPVWCFCVAK 289
FLFTSE+V EGHPD +CD ISDA++D L QDP A+V E L F A+
Sbjct: 5 FLFTSEAVTEGHPDCVCDIISDAVVDRFLQQDPYARVVTECALSKSVVFLAAR 57
>UniRef50_Q2GDS4 Cluster: S-adenosylmethionine synthetase; n=1;
Neorickettsia sennetsu str. Miyayama|Rep:
S-adenosylmethionine synthetase - Neorickettsia sennetsu
(strain Miyayama)
Length = 382
Score = 57.6 bits (133), Expect = 2e-07
Identities = 24/43 (55%), Positives = 33/43 (76%)
Frame = +2
Query: 137 FTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKLKP 265
F+SE+V GHPDK+ DQISD +LD +L +DP ++VA ET + P
Sbjct: 8 FSSEAVLPGHPDKIADQISDLVLDTYLQKDPSSRVAAETMVTP 50
Score = 51.6 bits (118), Expect = 1e-05
Identities = 30/81 (37%), Positives = 48/81 (59%), Gaps = 2/81 (2%)
Frame = +1
Query: 271 VLLCGEITSK--ANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVH 444
V++ GEI N + ++ +R +K IGY+ D+++ ++ L +QSP I+AG+
Sbjct: 53 VIVAGEIYGPEVTNAELEEKIRLFLKGIGYEKHL--LDWESLEIVNLLHEQSPEISAGL- 109
Query: 445 ENRNDEEVGARDQGLMFGYAT 507
R +GA DQG+MFGYAT
Sbjct: 110 --RRSASLGAGDQGVMFGYAT 128
>UniRef50_Q2LSR0 Cluster: S-adenosylmethionine synthetase; n=1;
Syntrophus aciditrophicus SB|Rep: S-adenosylmethionine
synthetase - Syntrophus aciditrophicus (strain SB)
Length = 392
Score = 56.8 bits (131), Expect = 4e-07
Identities = 26/81 (32%), Positives = 49/81 (60%), Gaps = 1/81 (1%)
Frame = +1
Query: 265 GMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVH 444
G+ ++ GE+ ++ VD ++ VR+TV +GY D G + + ++ + QSP+I G
Sbjct: 54 GLCIVGGEVATRIYVDIERCVRDTVLKLGYCDYELGLNGNSMGILNTIIPQSPDINIGTR 113
Query: 445 ENRND-EEVGARDQGLMFGYA 504
+ +E+GA DQG+++G+A
Sbjct: 114 ADLGKYKEIGAGDQGIIYGFA 134
>UniRef50_Q6SZ22 Cluster: S-adenosylmethionine synthetase; n=4;
Streptococcus|Rep: S-adenosylmethionine synthetase -
Streptococcus pyogenes
Length = 353
Score = 56.4 bits (130), Expect = 5e-07
Identities = 25/47 (53%), Positives = 32/47 (68%)
Frame = +2
Query: 122 GSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKLK 262
G + + +SE V GHPDK+CDQISDAIL L D ++VA ET +K
Sbjct: 6 GGIMIISSEQVSVGHPDKICDQISDAILTECLKYDKSSRVAVETLIK 52
Score = 41.1 bits (92), Expect = 0.021
Identities = 35/108 (32%), Positives = 49/108 (45%)
Frame = +1
Query: 259 KTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAG 438
K V++ GEI+++ + + +VR+ V+ +G K V L QS +IA G
Sbjct: 52 KDNQVVVAGEISTRHYFNLENIVRQVVEPLGM---------KNVRVTNLLGLQSSDIAQG 102
Query: 439 VHENRNDEEVGARDQGLMFGYATVRQKNACR*L*CLHTNSIRKLQSSG 582
V GA DQG+MFGYAT L T + KL S G
Sbjct: 103 VDNG------GAGDQGMMFGYATDETPEYLPLPYVLATRVLEKLMSLG 144
>UniRef50_A6QA94 Cluster: S-adenosylmethionine synthetase; n=20;
Epsilonproteobacteria|Rep: S-adenosylmethionine
synthetase - Sulfurovum sp. (strain NBC37-1)
Length = 405
Score = 56.4 bits (130), Expect = 5e-07
Identities = 25/41 (60%), Positives = 32/41 (78%)
Frame = +2
Query: 128 VFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 250
++LFTSESV GHPDK D I+D I+D+ L +DP+AKVA E
Sbjct: 1 MYLFTSESVSAGHPDKCADLIADTIVDSLLQRDPNAKVATE 41
Score = 49.2 bits (112), Expect = 8e-05
Identities = 31/86 (36%), Positives = 51/86 (59%), Gaps = 7/86 (8%)
Frame = +1
Query: 271 VLLCGEI-TSKA--NVDYQKVVRETVKHIGYDDSS----KGFDYKTCSVMLALDQQSPNI 429
+++ GE+ TS A NV Y++ ++ ++ IGY + + F + + + +QSP+I
Sbjct: 49 IIIGGEVKTSTAVDNVFYEECAQKALEKIGYPEGGFKRGETFFPDEAEIEVYVSKQSPDI 108
Query: 430 AAGVHENRNDEEVGARDQGLMFGYAT 507
GV + N E+GA DQG+MFGYAT
Sbjct: 109 TMGVVKEGN--EIGAGDQGMMFGYAT 132
>UniRef50_P78003 Cluster: S-adenosylmethionine synthetase; n=4;
Mycoplasma|Rep: S-adenosylmethionine synthetase -
Mycoplasma pneumoniae
Length = 383
Score = 56.4 bits (130), Expect = 5e-07
Identities = 22/38 (57%), Positives = 30/38 (78%)
Frame = +2
Query: 137 FTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 250
+ +E+VG GHPDK+CDQI+D+ILD + Q P + VACE
Sbjct: 13 YVAEAVGRGHPDKICDQIADSILDECIKQSPTSHVACE 50
Score = 37.1 bits (82), Expect = 0.34
Identities = 23/79 (29%), Positives = 41/79 (51%)
Frame = +1
Query: 268 MVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVHE 447
++++ GEI + VD + + + +GY ++ F + +C ++ QS I V
Sbjct: 57 LIMVGGEILTTGYVDVVQTGWKVLNRLGYTEND--FSFLSC-----INSQSSEINQAVQS 109
Query: 448 NRNDEEVGARDQGLMFGYA 504
N +E+GA DQG+ GYA
Sbjct: 110 N---DEIGAGDQGITVGYA 125
>UniRef50_O09486 Cluster: S-adenosylmethionine synthetase; n=1;
Amoeba proteus|Rep: S-adenosylmethionine synthetase -
Amoeba proteus (Amoeba)
Length = 426
Score = 56.4 bits (130), Expect = 5e-07
Identities = 36/92 (39%), Positives = 42/92 (45%), Gaps = 2/92 (2%)
Frame = +1
Query: 259 KTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAG 438
K +V L GE+T + RE V IGY D TCSV + + Q I
Sbjct: 54 KGNVVGLFGEVTCQKTFPTISWFRELVTEIGYSREDLDLDPTTCSVHINVRGQEAEIRGV 113
Query: 439 VH--ENRNDEEVGARDQGLMFGYATVRQKNAC 528
VH E E +GA DQGLMFGYAT C
Sbjct: 114 VHNQERAAKETLGAGDQGLMFGYATDETPERC 145
Score = 51.2 bits (117), Expect = 2e-05
Identities = 25/54 (46%), Positives = 33/54 (61%), Gaps = 4/54 (7%)
Frame = +2
Query: 113 MEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAK----VACETKLK 262
M+ + +LF SE+V GHPDK CDQ+SD +LD L + K VA ET +K
Sbjct: 1 MQQNTRYLFASEAVSRGHPDKACDQVSDRVLDYCLQAEKKCKKASRVALETTIK 54
>UniRef50_Q5FGR4 Cluster: S-adenosylmethionine synthetase; n=13;
Rickettsiales|Rep: S-adenosylmethionine synthetase -
Ehrlichia ruminantium (strain Gardel)
Length = 401
Score = 54.0 bits (124), Expect = 3e-06
Identities = 30/81 (37%), Positives = 45/81 (55%), Gaps = 3/81 (3%)
Frame = +1
Query: 271 VLLCGEITSKANVD---YQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGV 441
V + GEI NVD Q + R +K IGY+ GF ++ + + + +QSP+I GV
Sbjct: 58 VFIAGEICG-VNVDNSIIQSIARSVIKEIGYEQD--GFHWENVDIEILIHEQSPDIIVGV 114
Query: 442 HENRNDEEVGARDQGLMFGYA 504
+ N GA DQG+++GYA
Sbjct: 115 NSGENQ---GAGDQGIVYGYA 132
Score = 53.6 bits (123), Expect = 4e-06
Identities = 24/43 (55%), Positives = 31/43 (72%)
Frame = +2
Query: 125 SVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACET 253
S ++ TSESV GHPDK+ DQISDAILD +++ +P A ET
Sbjct: 9 SSYIITSESVSSGHPDKIADQISDAILDYYISLNPFVHTAIET 51
>UniRef50_UPI00015BD1C2 Cluster: UPI00015BD1C2 related cluster; n=1;
unknown|Rep: UPI00015BD1C2 UniRef100 entry - unknown
Length = 372
Score = 53.6 bits (123), Expect = 4e-06
Identities = 28/82 (34%), Positives = 45/82 (54%)
Frame = +1
Query: 262 TGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGV 441
+ +V + GE++S A VD Q V ++ +K +GY GFD V+ ++++QSP IA +
Sbjct: 47 SNIVFIAGEVSSSAYVDLQIVSKKAIKEVGYTKPEYGFDGDLIGVISSINEQSPEIALCI 106
Query: 442 HENRNDEEVGARDQGLMFGYAT 507
GA D ++ GYAT
Sbjct: 107 ASE------GAGDSAIVVGYAT 122
Score = 41.9 bits (94), Expect = 0.012
Identities = 19/39 (48%), Positives = 26/39 (66%)
Frame = +2
Query: 143 SESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKL 259
+ES EGHPDK+ D ISD ILD + +DP ++V+ L
Sbjct: 7 AESPFEGHPDKLADIISDEILDEFMRKDPFSRVSINVLL 45
>UniRef50_A6PKG8 Cluster: Methionine adenosyltransferase precursor;
n=1; Victivallis vadensis ATCC BAA-548|Rep: Methionine
adenosyltransferase precursor - Victivallis vadensis
ATCC BAA-548
Length = 338
Score = 46.8 bits (106), Expect = 4e-04
Identities = 22/43 (51%), Positives = 29/43 (67%)
Frame = +2
Query: 134 LFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKLK 262
L TSE V GHPDK+ D IS +LD HL++DP + A E ++K
Sbjct: 2 LKTSEWVSLGHPDKIADYISCYLLDRHLDRDPYTRFAVEVQIK 44
Score = 37.9 bits (84), Expect = 0.20
Identities = 35/94 (37%), Positives = 42/94 (44%), Gaps = 10/94 (10%)
Frame = +1
Query: 253 QTKTGMVLLCGEITSKANV---DYQKVVRETVKHIGYDDSSK---GFDYKTCS----VML 402
Q K V L GE+TSKAN D VR V IGY + G + C V
Sbjct: 42 QIKDNHVTLGGEVTSKANYSPEDIAAFVRAAVNQIGYTPEYQKRWGKENTICGDDLIVTQ 101
Query: 403 ALDQQSPNIAAGVHENRNDEEVGARDQGLMFGYA 504
+ QQSP+IA GV + G DQG+ G A
Sbjct: 102 HIGQQSPDIAQGVDAD------GYGDQGIFHGMA 129
>UniRef50_Q7R6Z1 Cluster: Putative uncharacterized protein PY07799;
n=2; cellular organisms|Rep: Putative uncharacterized
protein PY07799 - Plasmodium yoelii yoelii
Length = 1022
Score = 46.4 bits (105), Expect = 6e-04
Identities = 32/102 (31%), Positives = 46/102 (45%)
Frame = -3
Query: 504 GITEHQALVSCPNFLVISVLMHPSSNVW*LLV*CEHHTACLVIKAFGRIIITNMFDRFAH 325
G+ EHQ LV+ F+V+ +H +V LL A L I+A +++ ++ AH
Sbjct: 898 GVAEHQTLVARSLFVVVE-FVHTHGDVGRLLADGGQDGAALPIEADFGVVVADLVHDLAH 956
Query: 324 NFLIIHVSFGCDFATQKHHTGFSLVSHATFASGS*FRCASRI 199
FL +H G DFA + H G H G C RI
Sbjct: 957 QFLGVHPGGGGDFAGEHDHAGLHEGFHGHAGLG--ILCQDRI 996
>UniRef50_Q6A7D8 Cluster: S-adenosylmethionine synthetase; n=11;
Bacteria|Rep: S-adenosylmethionine synthetase -
Propionibacterium acnes
Length = 396
Score = 45.2 bits (102), Expect = 0.001
Identities = 22/37 (59%), Positives = 26/37 (70%)
Frame = +2
Query: 140 TSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 250
T+ESV GHPDK+ DQI+D ILD L D A+VA E
Sbjct: 6 TAESVCAGHPDKLADQIADQILDDILYDDKAARVAVE 42
>UniRef50_Q1VNA9 Cluster: S-adenosylmethionine synthetase; n=1;
Psychroflexus torquis ATCC 700755|Rep:
S-adenosylmethionine synthetase - Psychroflexus torquis
ATCC 700755
Length = 344
Score = 44.8 bits (101), Expect = 0.002
Identities = 30/84 (35%), Positives = 45/84 (53%), Gaps = 3/84 (3%)
Frame = +1
Query: 265 GMVLLCGEITSKANV---DYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAA 435
G+V++ GEI+ AN+ D + +V E + S + F+ ++ L QS I A
Sbjct: 34 GLVMVGGEISEIANISTEDIKTIVHEALNKT-IKTSFEDFNLDRLNIYNELTPQSEEIRA 92
Query: 436 GVHENRNDEEVGARDQGLMFGYAT 507
V E DE+ GA DQG+M G+AT
Sbjct: 93 AVEE---DEDQGAGDQGIMIGFAT 113
>UniRef50_Q95QX7 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 84
Score = 44.4 bits (100), Expect = 0.002
Identities = 18/19 (94%), Positives = 18/19 (94%)
Frame = +2
Query: 131 FLFTSESVGEGHPDKMCDQ 187
FLFTSESV EGHPDKMCDQ
Sbjct: 6 FLFTSESVSEGHPDKMCDQ 24
>UniRef50_Q027Y1 Cluster: Methionine adenosyltransferase; n=1;
Solibacter usitatus Ellin6076|Rep: Methionine
adenosyltransferase - Solibacter usitatus (strain
Ellin6076)
Length = 364
Score = 37.9 bits (84), Expect = 0.20
Identities = 16/39 (41%), Positives = 25/39 (64%)
Frame = +2
Query: 134 LFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 250
L+ +E V GHPDK+CD I+DA+++ + + A A E
Sbjct: 2 LYAAEYVLPGHPDKLCDAIADALVEEAVRHEKRALCAIE 40
>UniRef50_A4DEX8 Cluster: Putative uncharacterized protein; n=1;
Listeria monocytogenes FSL N1-017|Rep: Putative
uncharacterized protein - Listeria monocytogenes FSL
N1-017
Length = 277
Score = 37.9 bits (84), Expect = 0.20
Identities = 19/64 (29%), Positives = 33/64 (51%)
Frame = +2
Query: 146 ESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKLKPVWCFCVAKSHPKLTWIIKKL 325
E V HPDK+ D+IS AI+D ++ + K+A E + C + ++ L++ +
Sbjct: 20 EKVNPSHPDKIADRISGAIVDLAYQEETNPKIAVEVLIGHGICHVIIETSAALSFEEVRK 79
Query: 326 CAKR 337
KR
Sbjct: 80 AIKR 83
>UniRef50_UPI0000ECA413 Cluster: Endothelial cell-selective adhesion
molecule precursor.; n=2; Gallus gallus|Rep: Endothelial
cell-selective adhesion molecule precursor. - Gallus
gallus
Length = 395
Score = 35.5 bits (78), Expect = 1.1
Identities = 15/57 (26%), Positives = 28/57 (49%)
Frame = +2
Query: 188 ISDAILDAHLNQDPDAKVACETKLKPVWCFCVAKSHPKLTWIIKKLCAKRSNILVMM 358
+ A+L+ H+ V E + P W ++ P ++W++KK AK+ IL +
Sbjct: 23 VCSAVLEVHVGTGSVYSVEGEGAVLPAWYTSSSQKRPYISWMLKKAAAKQFQILTYL 79
>UniRef50_Q8FXU7 Cluster: Protease, putative; n=6; Brucellaceae|Rep:
Protease, putative - Brucella suis
Length = 261
Score = 35.1 bits (77), Expect = 1.4
Identities = 11/37 (29%), Positives = 24/37 (64%)
Frame = +2
Query: 107 YDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHL 217
YD + G++ + SE++G+GH + + D + A+ +A +
Sbjct: 50 YDSDSGAMLAYVSENIGKGHAEVLMDYVGQAMREAQI 86
>UniRef50_Q8ETA1 Cluster: Hypothetical conserved protein; n=1;
Oceanobacillus iheyensis|Rep: Hypothetical conserved
protein - Oceanobacillus iheyensis
Length = 868
Score = 35.1 bits (77), Expect = 1.4
Identities = 22/101 (21%), Positives = 44/101 (43%), Gaps = 2/101 (1%)
Frame = +2
Query: 56 MPETSKMNGYAKTNGHSYDMEDGSVFLFTSESVGEG--HPDKMCDQISDAILDAHLNQDP 229
+ ET +GY K G + +E G + + E GEG + ++ D + + N +
Sbjct: 133 LSETLLQSGYDKEIGDTITLEVGERYSLSDEMEGEGPLNQTVSAERTEDGLAEELRNTEE 192
Query: 230 DAKVACETKLKPVWCFCVAKSHPKLTWIIKKLCAKRSNILV 352
T +P+W + A + L++I + + + N+ V
Sbjct: 193 HTFTIVGTIEEPLWDYSWAPGYSMLSYIDEDILSTEENVTV 233
>UniRef50_A6RT45 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 345
Score = 34.3 bits (75), Expect = 2.4
Identities = 14/34 (41%), Positives = 24/34 (70%)
Frame = +1
Query: 124 ISIFVHIGICWRGSSRQNVRPNKRRYSRRASESG 225
I+ +H+G+C G+SR++V+ +R SR+A SG
Sbjct: 282 IAWVIHVGMCCCGASRRDVKSGRRMGSRKAYSSG 315
>UniRef50_Q15TP8 Cluster: Adenosine deaminase; n=2;
Gammaproteobacteria|Rep: Adenosine deaminase -
Pseudoalteromonas atlantica (strain T6c / BAA-1087)
Length = 537
Score = 33.9 bits (74), Expect = 3.2
Identities = 15/52 (28%), Positives = 26/52 (50%)
Frame = +1
Query: 307 VDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAGVHENRNDE 462
VD + + + +G +D+ KG+ + S + L Q+ PNI +H DE
Sbjct: 317 VDRHRDIYVGINMVGREDNDKGYPLRFLSTLRKLRQRIPNIPLAIHAGEVDE 368
>UniRef50_Q4QGM3 Cluster: Putative uncharacterized protein; n=3;
Leishmania|Rep: Putative uncharacterized protein -
Leishmania major
Length = 846
Score = 33.9 bits (74), Expect = 3.2
Identities = 18/46 (39%), Positives = 25/46 (54%)
Frame = -2
Query: 556 SLCASTTVNGMHSSVSLWHNRTSSPGLVPQLPRHFCSHAPQQQCLV 419
+LC S T N M +S+ HN S G+V QL R C H ++ L+
Sbjct: 493 TLCRSLTTNAMLKVLSMRHNNLSPDGVV-QLGRSLCRHPCLERLLL 537
>UniRef50_A4A0G4 Cluster: DNA-binding protein; n=1; Blastopirellula
marina DSM 3645|Rep: DNA-binding protein -
Blastopirellula marina DSM 3645
Length = 687
Score = 33.5 bits (73), Expect = 4.2
Identities = 13/33 (39%), Positives = 24/33 (72%)
Frame = +2
Query: 146 ESVGEGHPDKMCDQISDAILDAHLNQDPDAKVA 244
++V GHP ++ + + DA+L+A + + PDAK+A
Sbjct: 311 KAVRLGHPARVSESLHDALLEALVREHPDAKLA 343
>UniRef50_A7SQA7 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 895
Score = 33.5 bits (73), Expect = 4.2
Identities = 16/46 (34%), Positives = 28/46 (60%), Gaps = 1/46 (2%)
Frame = +3
Query: 9 RGTVWGYISGLTLNSECRRLQK*MDTRK-PTDTVMIWKMDQYFCSH 143
RG VW ++GL+ N E K + T++ PT+ V++W + + F +H
Sbjct: 406 RGQVWQMMAGLSENDELVDSYKHLFTKESPTEQVIVWDIHRTFPAH 451
>UniRef50_Q7QFB7 Cluster: ENSANGP00000022002; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000022002 - Anopheles gambiae
str. PEST
Length = 829
Score = 33.1 bits (72), Expect = 5.6
Identities = 17/46 (36%), Positives = 24/46 (52%)
Frame = +3
Query: 459 RGSWGTRPGLDVRLCHSETEECMPLTVVLAHKLNQKIAELRRNGEF 596
RG+ RPG RL H + E+ + L HK NQ + R+NG +
Sbjct: 53 RGTQSKRPGQLHRLSHEKREQTLGKEFALLHKTNQ-FMDARQNGRY 97
>UniRef50_UPI0000498BC3 Cluster: conserved hypothetical protein;
n=1; Entamoeba histolytica HM-1:IMSS|Rep: conserved
hypothetical protein - Entamoeba histolytica HM-1:IMSS
Length = 592
Score = 32.7 bits (71), Expect = 7.4
Identities = 16/48 (33%), Positives = 24/48 (50%)
Frame = +1
Query: 199 YSRRASESGSGRKSCM*NQTKTGMVLLCGEITSKANVDYQKVVRETVK 342
+ R E G + +C NQTK G ++CG + ++V ETVK
Sbjct: 413 HCRHVFEDGEEKVACYVNQTKDGNCVVCGCYYTHHKYSTYRIVYETVK 460
>UniRef50_UPI00006A2011 Cluster: Tumor necrosis factor receptor
superfamily member 19L precursor (Receptor expressed in
lymphoid tissues).; n=1; Xenopus tropicalis|Rep: Tumor
necrosis factor receptor superfamily member 19L
precursor (Receptor expressed in lymphoid tissues). -
Xenopus tropicalis
Length = 313
Score = 32.7 bits (71), Expect = 7.4
Identities = 15/40 (37%), Positives = 19/40 (47%)
Frame = -2
Query: 478 LVPQLPRHFCSHAPQQQCLVIVGLVRASHCMSCNQSLWTN 359
L+PQ+P H C H + L S C C+Q WTN
Sbjct: 223 LLPQMP-HLCKHQHHLHTVQGPALPTGSCCSRCSQKKWTN 261
>UniRef50_A7MES0 Cluster: Putative uncharacterized protein; n=1;
Enterobacter sakazakii ATCC BAA-894|Rep: Putative
uncharacterized protein - Enterobacter sakazakii ATCC
BAA-894
Length = 1383
Score = 32.7 bits (71), Expect = 7.4
Identities = 19/51 (37%), Positives = 25/51 (49%)
Frame = +2
Query: 119 DGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKLKPVW 271
D LF+ V E PD D+ +D +L+ H DP A A T + PVW
Sbjct: 294 DADDVLFSGHKVTE--PDAFYDE-NDPLLNGHSIADPAAVAAAATPVAPVW 341
>UniRef50_A0NE72 Cluster: ENSANGP00000030279; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000030279 - Anopheles gambiae
str. PEST
Length = 161
Score = 32.7 bits (71), Expect = 7.4
Identities = 18/57 (31%), Positives = 32/57 (56%), Gaps = 1/57 (1%)
Frame = -3
Query: 390 ACLVIKAFGRIIITNMF-DRFAHNFLIIHVSFGCDFATQKHHTGFSLVSHATFASGS 223
+C+++K+ R+I N+ + + N +++H + H GF+ VS A FASGS
Sbjct: 86 SCVIVKSLPRLISLNLSRNSLSENSIVLH-NLPSLVTLVLSHNGFNQVSVALFASGS 141
>UniRef50_Q4SDE4 Cluster: Chromosome 3 SCAF14639, whole genome
shotgun sequence; n=4; Tetraodontidae|Rep: Chromosome 3
SCAF14639, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 825
Score = 32.3 bits (70), Expect = 9.8
Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Frame = +1
Query: 292 TSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNI-AAGVHENRNDEEV 468
TS+ N+DYQ+VVR + +D KGF T V L+ + +I +HE N+ ++
Sbjct: 713 TSEINLDYQEVVRYKKRFHKFDKERKGF-ITTVDVQQVLENINVHIDENSLHEILNEVDL 771
Query: 469 GARDQ 483
Q
Sbjct: 772 NKNGQ 776
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 690,537,130
Number of Sequences: 1657284
Number of extensions: 14540210
Number of successful extensions: 36764
Number of sequences better than 10.0: 51
Number of HSP's better than 10.0 without gapping: 35391
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 36713
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 46051731393
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -