Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= NV021157
(626 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X68836-1|CAA48726.1| 395|Homo sapiens S-adenosylmethionine synt... 154 2e-37
DQ083239-1|AAY85355.1| 395|Homo sapiens methionine adenosyltran... 154 2e-37
BC001854-1|AAH01854.1| 395|Homo sapiens methionine adenosyltran... 154 2e-37
BC001686-1|AAH01686.1| 395|Homo sapiens methionine adenosyltran... 154 2e-37
AC016753-1|AAY24339.1| 395|Homo sapiens unknown protein. 154 2e-37
X69078-1|CAA48822.1| 395|Homo sapiens methionine adenosyltransf... 149 1e-35
D49357-1|BAA08355.1| 395|Homo sapiens S-adenosylmethionine synt... 149 1e-35
BC018359-1|AAH18359.1| 395|Homo sapiens methionine adenosyltran... 149 1e-35
AL359195-2|CAI13695.1| 395|Homo sapiens methionine adenosyltran... 149 1e-35
AL359195-3|CAI13696.1| 145|Homo sapiens methionine adenosyltran... 84 4e-16
BC028352-1|AAH28352.1| 691|Homo sapiens TBC1 domain family, mem... 30 5.8
AK022147-1|BAB13971.1| 674|Homo sapiens protein ( Homo sapiens ... 30 7.7
>X68836-1|CAA48726.1| 395|Homo sapiens S-adenosylmethionine
synthetase protein.
Length = 395
Score = 154 bits (374), Expect = 2e-37
Identities = 77/123 (62%), Positives = 92/123 (74%), Gaps = 1/123 (0%)
Frame = +1
Query: 259 KTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAG 438
KTGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL+QQSP+IA G
Sbjct: 61 KTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQG 120
Query: 439 VHENRNDEEVGARDQGLMFGYATVRQKNACR*L*CLHTNSIR-KLQSSGEMENFWWARPD 615
VH +RN+E++GA DQGLMFGYAT + C L + + + KL W RPD
Sbjct: 121 VHLDRNEEDIGAGDQGLMFGYAT-DETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPD 179
Query: 616 SKT 624
SKT
Sbjct: 180 SKT 182
Score = 93.9 bits (223), Expect = 4e-19
Identities = 47/64 (73%), Positives = 53/64 (82%), Gaps = 1/64 (1%)
Frame = +2
Query: 74 MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 250
MNG + NG H +E+G+ FLFTSESVGEGHPDK+CDQISDA+LDAHL QDPDAKVACE
Sbjct: 1 MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57
Query: 251 TKLK 262
T K
Sbjct: 58 TVAK 61
>DQ083239-1|AAY85355.1| 395|Homo sapiens methionine
adenosyltransferase II protein.
Length = 395
Score = 154 bits (374), Expect = 2e-37
Identities = 77/123 (62%), Positives = 92/123 (74%), Gaps = 1/123 (0%)
Frame = +1
Query: 259 KTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAG 438
KTGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL+QQSP+IA G
Sbjct: 61 KTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQG 120
Query: 439 VHENRNDEEVGARDQGLMFGYATVRQKNACR*L*CLHTNSIR-KLQSSGEMENFWWARPD 615
VH +RN+E++GA DQGLMFGYAT + C L + + + KL W RPD
Sbjct: 121 VHLDRNEEDIGAGDQGLMFGYAT-DETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPD 179
Query: 616 SKT 624
SKT
Sbjct: 180 SKT 182
Score = 93.9 bits (223), Expect = 4e-19
Identities = 47/64 (73%), Positives = 53/64 (82%), Gaps = 1/64 (1%)
Frame = +2
Query: 74 MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 250
MNG + NG H +E+G+ FLFTSESVGEGHPDK+CDQISDA+LDAHL QDPDAKVACE
Sbjct: 1 MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57
Query: 251 TKLK 262
T K
Sbjct: 58 TVAK 61
>BC001854-1|AAH01854.1| 395|Homo sapiens methionine
adenosyltransferase II, alpha protein.
Length = 395
Score = 154 bits (374), Expect = 2e-37
Identities = 77/123 (62%), Positives = 92/123 (74%), Gaps = 1/123 (0%)
Frame = +1
Query: 259 KTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAG 438
KTGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL+QQSP+IA G
Sbjct: 61 KTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQG 120
Query: 439 VHENRNDEEVGARDQGLMFGYATVRQKNACR*L*CLHTNSIR-KLQSSGEMENFWWARPD 615
VH +RN+E++GA DQGLMFGYAT + C L + + + KL W RPD
Sbjct: 121 VHLDRNEEDIGAGDQGLMFGYAT-DETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPD 179
Query: 616 SKT 624
SKT
Sbjct: 180 SKT 182
Score = 93.9 bits (223), Expect = 4e-19
Identities = 47/64 (73%), Positives = 53/64 (82%), Gaps = 1/64 (1%)
Frame = +2
Query: 74 MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 250
MNG + NG H +E+G+ FLFTSESVGEGHPDK+CDQISDA+LDAHL QDPDAKVACE
Sbjct: 1 MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57
Query: 251 TKLK 262
T K
Sbjct: 58 TVAK 61
>BC001686-1|AAH01686.1| 395|Homo sapiens methionine
adenosyltransferase II, alpha protein.
Length = 395
Score = 154 bits (374), Expect = 2e-37
Identities = 77/123 (62%), Positives = 92/123 (74%), Gaps = 1/123 (0%)
Frame = +1
Query: 259 KTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAG 438
KTGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL+QQSP+IA G
Sbjct: 61 KTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQG 120
Query: 439 VHENRNDEEVGARDQGLMFGYATVRQKNACR*L*CLHTNSIR-KLQSSGEMENFWWARPD 615
VH +RN+E++GA DQGLMFGYAT + C L + + + KL W RPD
Sbjct: 121 VHLDRNEEDIGAGDQGLMFGYAT-DETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPD 179
Query: 616 SKT 624
SKT
Sbjct: 180 SKT 182
Score = 93.9 bits (223), Expect = 4e-19
Identities = 47/64 (73%), Positives = 53/64 (82%), Gaps = 1/64 (1%)
Frame = +2
Query: 74 MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 250
MNG + NG H +E+G+ FLFTSESVGEGHPDK+CDQISDA+LDAHL QDPDAKVACE
Sbjct: 1 MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57
Query: 251 TKLK 262
T K
Sbjct: 58 TVAK 61
>AC016753-1|AAY24339.1| 395|Homo sapiens unknown protein.
Length = 395
Score = 154 bits (374), Expect = 2e-37
Identities = 77/123 (62%), Positives = 92/123 (74%), Gaps = 1/123 (0%)
Frame = +1
Query: 259 KTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAG 438
KTGM+LL GEITS+A VDYQKVVRE VKHIGYDDSSKGFDYKTC+V++AL+QQSP+IA G
Sbjct: 61 KTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQG 120
Query: 439 VHENRNDEEVGARDQGLMFGYATVRQKNACR*L*CLHTNSIR-KLQSSGEMENFWWARPD 615
VH +RN+E++GA DQGLMFGYAT + C L + + + KL W RPD
Sbjct: 121 VHLDRNEEDIGAGDQGLMFGYAT-DETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPD 179
Query: 616 SKT 624
SKT
Sbjct: 180 SKT 182
Score = 93.9 bits (223), Expect = 4e-19
Identities = 47/64 (73%), Positives = 53/64 (82%), Gaps = 1/64 (1%)
Frame = +2
Query: 74 MNGYAKTNG-HSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACE 250
MNG + NG H +E+G+ FLFTSESVGEGHPDK+CDQISDA+LDAHL QDPDAKVACE
Sbjct: 1 MNG--QLNGFHEAFIEEGT-FLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACE 57
Query: 251 TKLK 262
T K
Sbjct: 58 TVAK 61
>X69078-1|CAA48822.1| 395|Homo sapiens methionine
adenosyltransferase protein.
Length = 395
Score = 149 bits (360), Expect = 1e-35
Identities = 73/123 (59%), Positives = 91/123 (73%), Gaps = 1/123 (0%)
Frame = +1
Query: 259 KTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAG 438
KTGMVLLCGEITS A VDYQ+VVR+T+KHIGYDDS+KGFD+KTC+V++AL+QQSP+IA
Sbjct: 61 KTGMVLLCGEITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQC 120
Query: 439 VHENRNDEEVGARDQGLMFGYATVRQKNACR*L*CLHTNSIRKLQSSGEMENFW-WARPD 615
VH +RN+E+VGA DQGLMFGYAT + C L + + + + W RPD
Sbjct: 121 VHLDRNEEDVGAGDQGLMFGYAT-DETEECMPLTIILAHKLNARMADLRRSGLLPWLRPD 179
Query: 616 SKT 624
SKT
Sbjct: 180 SKT 182
Score = 88.2 bits (209), Expect = 2e-17
Identities = 39/52 (75%), Positives = 46/52 (88%)
Frame = +2
Query: 107 YDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKLK 262
+ + +G VF+FTSESVGEGHPDK+CDQISDA+LDAHL QDP+AKVACET K
Sbjct: 11 HSLSEG-VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCK 61
>D49357-1|BAA08355.1| 395|Homo sapiens S-adenosylmethionine
synthetase protein.
Length = 395
Score = 149 bits (360), Expect = 1e-35
Identities = 73/123 (59%), Positives = 91/123 (73%), Gaps = 1/123 (0%)
Frame = +1
Query: 259 KTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAG 438
KTGMVLLCGEITS A VDYQ+VVR+T+KHIGYDDS+KGFD+KTC+V++AL+QQSP+IA
Sbjct: 61 KTGMVLLCGEITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQC 120
Query: 439 VHENRNDEEVGARDQGLMFGYATVRQKNACR*L*CLHTNSIRKLQSSGEMENFW-WARPD 615
VH +RN+E+VGA DQGLMFGYAT + C L + + + + W RPD
Sbjct: 121 VHLDRNEEDVGAGDQGLMFGYAT-DETEECMPLTIILAHKLNARMADLRRSGLLPWLRPD 179
Query: 616 SKT 624
SKT
Sbjct: 180 SKT 182
Score = 88.2 bits (209), Expect = 2e-17
Identities = 39/52 (75%), Positives = 46/52 (88%)
Frame = +2
Query: 107 YDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKLK 262
+ + +G VF+FTSESVGEGHPDK+CDQISDA+LDAHL QDP+AKVACET K
Sbjct: 11 HSLSEG-VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCK 61
>BC018359-1|AAH18359.1| 395|Homo sapiens methionine
adenosyltransferase I, alpha protein.
Length = 395
Score = 149 bits (360), Expect = 1e-35
Identities = 73/123 (59%), Positives = 91/123 (73%), Gaps = 1/123 (0%)
Frame = +1
Query: 259 KTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAG 438
KTGMVLLCGEITS A VDYQ+VVR+T+KHIGYDDS+KGFD+KTC+V++AL+QQSP+IA
Sbjct: 61 KTGMVLLCGEITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQC 120
Query: 439 VHENRNDEEVGARDQGLMFGYATVRQKNACR*L*CLHTNSIRKLQSSGEMENFW-WARPD 615
VH +RN+E+VGA DQGLMFGYAT + C L + + + + W RPD
Sbjct: 121 VHLDRNEEDVGAGDQGLMFGYAT-DETEECMPLTIILAHKLNARMADLRRSGLLPWLRPD 179
Query: 616 SKT 624
SKT
Sbjct: 180 SKT 182
Score = 88.2 bits (209), Expect = 2e-17
Identities = 39/52 (75%), Positives = 46/52 (88%)
Frame = +2
Query: 107 YDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKLK 262
+ + +G VF+FTSESVGEGHPDK+CDQISDA+LDAHL QDP+AKVACET K
Sbjct: 11 HSLSEG-VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCK 61
>AL359195-2|CAI13695.1| 395|Homo sapiens methionine
adenosyltransferase I, alpha protein.
Length = 395
Score = 149 bits (360), Expect = 1e-35
Identities = 73/123 (59%), Positives = 91/123 (73%), Gaps = 1/123 (0%)
Frame = +1
Query: 259 KTGMVLLCGEITSKANVDYQKVVRETVKHIGYDDSSKGFDYKTCSVMLALDQQSPNIAAG 438
KTGMVLLCGEITS A VDYQ+VVR+T+KHIGYDDS+KGFD+KTC+V++AL+QQSP+IA
Sbjct: 61 KTGMVLLCGEITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQC 120
Query: 439 VHENRNDEEVGARDQGLMFGYATVRQKNACR*L*CLHTNSIRKLQSSGEMENFW-WARPD 615
VH +RN+E+VGA DQGLMFGYAT + C L + + + + W RPD
Sbjct: 121 VHLDRNEEDVGAGDQGLMFGYAT-DETEECMPLTIILAHKLNARMADLRRSGLLPWLRPD 179
Query: 616 SKT 624
SKT
Sbjct: 180 SKT 182
Score = 88.2 bits (209), Expect = 2e-17
Identities = 39/52 (75%), Positives = 46/52 (88%)
Frame = +2
Query: 107 YDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPDAKVACETKLK 262
+ + +G VF+FTSESVGEGHPDK+CDQISDA+LDAHL QDP+AKVACET K
Sbjct: 11 HSLSEG-VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCK 61
>AL359195-3|CAI13696.1| 145|Homo sapiens methionine
adenosyltransferase I, alpha protein.
Length = 145
Score = 83.8 bits (198), Expect = 4e-16
Identities = 45/98 (45%), Positives = 62/98 (63%), Gaps = 4/98 (4%)
Frame = +1
Query: 343 HIGYDDSSK---GFDYKTCSVMLALDQQSPNIAAGVHENRNDEEVGARDQGLMFGYATVR 513
H+ D ++K GFD+KTC+V++AL+QQSP+IA VH +RN+E+VGA DQGLMFGYAT
Sbjct: 23 HLKQDPNAKVACGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQGLMFGYAT-D 81
Query: 514 QKNACR*L*CLHTNSIRKLQSSGEMENFW-WARPDSKT 624
+ C L + + + + W RPDSKT
Sbjct: 82 ETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDSKT 119
Score = 72.1 bits (169), Expect = 1e-12
Identities = 30/34 (88%), Positives = 33/34 (97%)
Frame = +2
Query: 146 ESVGEGHPDKMCDQISDAILDAHLNQDPDAKVAC 247
ESVGEGHPDK+CDQISDA+LDAHL QDP+AKVAC
Sbjct: 1 ESVGEGHPDKICDQISDAVLDAHLKQDPNAKVAC 34
>BC028352-1|AAH28352.1| 691|Homo sapiens TBC1 domain family, member
15 protein.
Length = 691
Score = 30.3 bits (65), Expect = 5.8
Identities = 20/66 (30%), Positives = 31/66 (46%)
Frame = +2
Query: 35 WANSKFRMPETSKMNGYAKTNGHSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAH 214
W K + P T+ M G++K + +D GS S + P +M D +SDAI
Sbjct: 235 WKKIK-KDPYTATMIGFSKVTNYIFDSLRGS-----DPSTHQRPPSEMADFLSDAIPGLK 288
Query: 215 LNQDPD 232
+NQ +
Sbjct: 289 INQQEE 294
>AK022147-1|BAB13971.1| 674|Homo sapiens protein ( Homo sapiens
cDNA FLJ12085 fis, clone HEMBB1002510, weakly similar to
GYP7 PROTEIN. ).
Length = 674
Score = 29.9 bits (64), Expect = 7.7
Identities = 18/58 (31%), Positives = 28/58 (48%)
Frame = +2
Query: 59 PETSKMNGYAKTNGHSYDMEDGSVFLFTSESVGEGHPDKMCDQISDAILDAHLNQDPD 232
P T+ M G++K + +D GS S + P +M D +SDAI +NQ +
Sbjct: 225 PYTATMIGFSKVTNYIFDSLRGS-----DPSTHQRPPSEMADFLSDAIPGLKINQQEE 277
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 102,838,133
Number of Sequences: 237096
Number of extensions: 2349208
Number of successful extensions: 8816
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 8424
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8792
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6804036910
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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