Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= NV021154
(632 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_A7T6B8 Cluster: Predicted protein; n=1; Nematostella ve... 136 5e-31
UniRef50_Q4S0L0 Cluster: Malic enzyme; n=2; Tetraodon nigrovirid... 132 7e-30
UniRef50_Q16798 Cluster: NADP-dependent malic enzyme, mitochondr... 132 7e-30
UniRef50_P23368 Cluster: NAD-dependent malic enzyme, mitochondri... 128 8e-29
UniRef50_Q5BX10 Cluster: Malic enzyme; n=1; Schistosoma japonicu... 126 3e-28
UniRef50_P48163 Cluster: NADP-dependent malic enzyme; n=63; Euka... 126 6e-28
UniRef50_A2ZQ54 Cluster: Malic enzyme; n=9; Oryza sativa|Rep: Ma... 122 7e-27
UniRef50_P06801 Cluster: NADP-dependent malic enzyme; n=52; cell... 122 7e-27
UniRef50_A0L5P5 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 121 2e-26
UniRef50_Q89G76 Cluster: Malic enzyme; n=3; cellular organisms|R... 118 2e-25
UniRef50_Q0AIF8 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 118 2e-25
UniRef50_A7CWP9 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 118 2e-25
UniRef50_P16243 Cluster: NADP-dependent malic enzyme, chloroplas... 113 4e-24
UniRef50_A7PC00 Cluster: Chromosome chr2 scaffold_11, whole geno... 109 5e-23
UniRef50_Q016K2 Cluster: NADP dependent malic enzyme; n=2; Ostre... 107 2e-22
UniRef50_A6SA55 Cluster: Malic enzyme; n=2; Sclerotiniaceae|Rep:... 101 1e-20
UniRef50_Q8D911 Cluster: NAD-dependent malic enzyme; n=187; cell... 100 3e-20
UniRef50_Q8I8I4 Cluster: Malic enzyme; n=4; Eukaryota|Rep: Malic... 98 1e-19
UniRef50_UPI0000D9F768 Cluster: PREDICTED: similar to Y48B6A.12,... 98 2e-19
UniRef50_A7IMB8 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 98 2e-19
UniRef50_A3QW96 Cluster: Malic enzyme; n=10; Tigriopus californi... 97 2e-19
UniRef50_Q86NT5 Cluster: Malic enzyme; n=2; Drosophila melanogas... 97 4e-19
UniRef50_Q4X1Z2 Cluster: NADP-dependent malic enzyme MaeA; n=11;... 97 4e-19
UniRef50_P37221 Cluster: NAD-dependent malic enzyme 62 kDa isofo... 95 9e-19
UniRef50_P78715 Cluster: Malic enzyme, hydrogenosomal precursor;... 95 9e-19
UniRef50_A1ZAF7 Cluster: Malic enzyme; n=5; Sophophora|Rep: Mali... 93 5e-18
UniRef50_Q00XN9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 93 7e-18
UniRef50_Q01AM5 Cluster: NADP+-dependent malic enzyme; n=2; Ostr... 90 4e-17
UniRef50_Q9HE50 Cluster: Malic enzyme; n=6; Pezizomycotina|Rep: ... 89 8e-17
UniRef50_A3BK03 Cluster: Malic enzyme; n=2; Oryza sativa|Rep: Ma... 89 1e-16
UniRef50_Q4PC56 Cluster: Malic enzyme; n=1; Ustilago maydis|Rep:... 88 1e-16
UniRef50_Q9RYN4 Cluster: Malate oxidoreductase; n=6; Deinococci|... 88 2e-16
UniRef50_Q875H8 Cluster: Malic enzyme; n=1; Mucor circinelloides... 88 2e-16
UniRef50_A0Q531 Cluster: NAD-dependent malic enzyme; n=10; Franc... 87 3e-16
UniRef50_A4RQC9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 87 3e-16
UniRef50_A2EKE3 Cluster: Malic enzyme; n=14; Trichomonadidae|Rep... 83 5e-15
UniRef50_A1SVL3 Cluster: Malic enzyme aka malate dehydrogenase (... 83 7e-15
UniRef50_Q4QAQ6 Cluster: Malic enzyme, putative; n=20; Trypanoso... 77 3e-13
UniRef50_P45868 Cluster: Probable NAD-dependent malic enzyme 2; ... 77 3e-13
UniRef50_Q7SHJ8 Cluster: Malic enzyme; n=12; Pezizomycotina|Rep:... 73 4e-12
UniRef50_Q5K758 Cluster: Malic enzyme; n=1; Filobasidiella neofo... 73 8e-12
UniRef50_A3YYQ0 Cluster: Malate oxidoreductase; n=1; Synechococc... 70 4e-11
UniRef50_A6XP71 Cluster: Malic enzyme protein 2; n=2; Mucoromyco... 70 4e-11
UniRef50_Q6AL43 Cluster: Related to NAD-dependent malic enzyme; ... 69 9e-11
UniRef50_Q95061 Cluster: Malic enzyme; n=2; Giardia intestinalis... 68 2e-10
UniRef50_A4SKB8 Cluster: NAD-dependent malic enzyme; n=2; Aeromo... 64 2e-09
UniRef50_A2QY66 Cluster: Malic enzyme; n=2; cellular organisms|R... 64 3e-09
UniRef50_Q5CS07 Cluster: Malic enzyme; n=2; Cryptosporidium|Rep:... 62 8e-09
UniRef50_P40375 Cluster: NAD-dependent malic enzyme; n=3; Schizo... 62 8e-09
UniRef50_A4RZU1 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 60 3e-08
UniRef50_Q48796 Cluster: Malolactic enzyme; n=49; Bacteria|Rep: ... 59 1e-07
UniRef50_A5C6I9 Cluster: Malic enzyme; n=1; Vitis vinifera|Rep: ... 58 2e-07
UniRef50_Q2HCG7 Cluster: Malic enzyme; n=1; Chaetomium globosum|... 58 2e-07
UniRef50_Q7K3R0 Cluster: Malic enzyme; n=2; Sophophora|Rep: Mali... 56 9e-07
UniRef50_Q8Y5Y8 Cluster: Lmo1915 protein; n=15; Firmicutes|Rep: ... 52 9e-06
UniRef50_Q5KEY3 Cluster: Malic enzyme; n=1; Filobasidiella neofo... 50 4e-05
UniRef50_Q5KBK5 Cluster: Nad-dependent malic enzyme, putative; n... 50 4e-05
UniRef50_P36013 Cluster: NAD-dependent malic enzyme, mitochondri... 49 1e-04
UniRef50_Q9S4T5 Cluster: NAD-malate oxidoreductase homolog; n=15... 47 3e-04
UniRef50_UPI0000DB7FF6 Cluster: PREDICTED: hypothetical protein,... 43 0.005
UniRef50_Q8S484 Cluster: Putative NADP-dependent malic enzyme; n... 41 0.028
UniRef50_A3XN08 Cluster: Putative uncharacterized protein; n=1; ... 34 2.5
UniRef50_Q08PM3 Cluster: Hemin ABC transporter, periplasmic hemi... 34 3.3
UniRef50_A1CKF3 Cluster: Stress response protein (Ish1), putativ... 34 3.3
UniRef50_Q1WD27 Cluster: ScfA; n=2; Emericella nidulans|Rep: Scf... 33 4.3
UniRef50_Q7NAH7 Cluster: Cysteinyl-tRNA synthetase; n=1; Mycopla... 33 5.7
UniRef50_Q1EI20 Cluster: Putative uncharacterized protein; n=2; ... 33 7.5
UniRef50_A0WC26 Cluster: Multi-sensor hybrid histidine kinase pr... 33 7.5
UniRef50_Q10PB7 Cluster: Expressed protein; n=1; Oryza sativa (j... 33 7.5
UniRef50_UPI00005A0FA5 Cluster: PREDICTED: hypothetical protein ... 32 10.0
UniRef50_Q4SBA5 Cluster: Chromosome undetermined SCAF14676, whol... 32 10.0
UniRef50_Q1MKF6 Cluster: Putative uncharacterized protein; n=1; ... 32 10.0
UniRef50_Q17IF3 Cluster: Putative uncharacterized protein; n=1; ... 32 10.0
>UniRef50_A7T6B8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 365
Score = 136 bits (328), Expect = 5e-31
Identities = 56/85 (65%), Positives = 73/85 (85%)
Frame = +2
Query: 254 INKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIH 433
+ KYI LM LL+RNE LF+R + D E+MPIVYTPTVGLAC+K+G+++RRPRGLFI+IH
Sbjct: 69 LEKYIQLMALLERNESLFFRVLFDYTEELMPIVYTPTVGLACRKYGMIFRRPRGLFISIH 128
Query: 434 DKGHVYDVLKNWPETDVRAIVVTDG 508
DKGH+ D++ NWP T+V+AIV+TDG
Sbjct: 129 DKGHIRDIVSNWPTTEVKAIVMTDG 153
Score = 73.7 bits (173), Expect = 3e-12
Identities = 32/41 (78%), Positives = 34/41 (82%)
Frame = +1
Query: 508 KRILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
+RILGLGDLG CGMGIPVGKLALYT GGI P CLP+ ID
Sbjct: 154 ERILGLGDLGCCGMGIPVGKLALYTVCGGIDPEGCLPVMID 194
Score = 33.9 bits (74), Expect = 3.3
Identities = 18/43 (41%), Positives = 22/43 (51%)
Frame = +3
Query: 129 GHGFYHRRASLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPL 257
G F +LGIHGLLPP V +QE Q + + R N L
Sbjct: 27 GLAFTLEERQILGIHGLLPPCVISQEIQAQRVYRELQRKPNDL 69
>UniRef50_Q4S0L0 Cluster: Malic enzyme; n=2; Tetraodon
nigroviridis|Rep: Malic enzyme - Tetraodon nigroviridis
(Green puffer)
Length = 694
Score = 132 bits (319), Expect = 7e-30
Identities = 55/85 (64%), Positives = 71/85 (83%)
Frame = +2
Query: 254 INKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIH 433
++KYI LM L DRNE LFYR + ++ + MPIVYTPTVGLACQ++GL +RRPRGLFITIH
Sbjct: 116 LDKYILLMTLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYGLAFRRPRGLFITIH 175
Query: 434 DKGHVYDVLKNWPETDVRAIVVTDG 508
D+GH+ +L +WPE D++A+VVTDG
Sbjct: 176 DRGHIATMLNSWPEEDIKAVVVTDG 200
Score = 44.4 bits (100), Expect = 0.002
Identities = 20/23 (86%), Positives = 22/23 (95%)
Frame = +1
Query: 508 KRILGLGDLGACGMGIPVGKLAL 576
+RILGLGDLG+ GMGIPVGKLAL
Sbjct: 201 ERILGLGDLGSYGMGIPVGKLAL 223
Score = 34.3 bits (75), Expect = 2.5
Identities = 15/32 (46%), Positives = 21/32 (65%)
Frame = +1
Query: 61 SGDGQPTSGLSGLDHLKHPGLNKGMAFTIEER 156
+ +G + G D ++P LNKGMAFT+EER
Sbjct: 51 ASEGSVRTKKRGYDITRNPHLNKGMAFTLEER 82
>UniRef50_Q16798 Cluster: NADP-dependent malic enzyme, mitochondrial
precursor; n=15; Bilateria|Rep: NADP-dependent malic
enzyme, mitochondrial precursor - Homo sapiens (Human)
Length = 604
Score = 132 bits (319), Expect = 7e-30
Identities = 59/96 (61%), Positives = 76/96 (79%)
Frame = +2
Query: 221 MQALDRQIRKSINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVY 400
M+ +RQ + ++KYI LM L DRNE LFYR + +V + MPIVYTPTVGLACQ +GL +
Sbjct: 94 MRYYERQ-QSDLDKYIILMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTF 152
Query: 401 RRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDG 508
RRPRGLFITIHDKGH+ +L +WPE +++A+VVTDG
Sbjct: 153 RRPRGLFITIHDKGHLATMLNSWPEDNIKAVVVTDG 188
Score = 72.9 bits (171), Expect = 6e-12
Identities = 31/41 (75%), Positives = 35/41 (85%)
Frame = +1
Query: 508 KRILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
+RILGLGDLG GMGIPVGKLALYTA GG+ P QCLP+ +D
Sbjct: 189 ERILGLGDLGCYGMGIPVGKLALYTACGGVNPQQCLPVLLD 229
Score = 33.5 bits (73), Expect = 4.3
Identities = 14/21 (66%), Positives = 17/21 (80%)
Frame = +1
Query: 94 GLDHLKHPGLNKGMAFTIEER 156
G D ++P LNKGMAFT+EER
Sbjct: 50 GYDVTRNPHLNKGMAFTLEER 70
>UniRef50_P23368 Cluster: NAD-dependent malic enzyme, mitochondrial
precursor; n=53; Eumetazoa|Rep: NAD-dependent malic
enzyme, mitochondrial precursor - Homo sapiens (Human)
Length = 584
Score = 128 bits (310), Expect = 8e-29
Identities = 51/91 (56%), Positives = 73/91 (80%)
Frame = +2
Query: 236 RQIRKSINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRG 415
+++ + KYIY+MG+ +RNE LFYR + D++ +MPIVYTPTVGLAC ++G ++RRP+G
Sbjct: 73 KKMTSPLEKYIYIMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKG 132
Query: 416 LFITIHDKGHVYDVLKNWPETDVRAIVVTDG 508
LFI+I D+GHV ++ NWPE V+A+VVTDG
Sbjct: 133 LFISISDRGHVRSIVDNWPENHVKAVVVTDG 163
Score = 68.9 bits (161), Expect = 9e-11
Identities = 30/41 (73%), Positives = 34/41 (82%)
Frame = +1
Query: 508 KRILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
+RILGLGDLG GMGIPVGKL LYTA GI+P +CLP+ ID
Sbjct: 164 ERILGLGDLGVYGMGIPVGKLCLYTACAGIRPDRCLPVCID 204
Score = 33.1 bits (72), Expect = 5.7
Identities = 15/51 (29%), Positives = 27/51 (52%)
Frame = +3
Query: 129 GHGFYHRRASLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLTSTSILWG 281
G F + +LG+ GLLPP+++TQ+ Q ++ + +PL + G
Sbjct: 37 GMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIYIMG 87
>UniRef50_Q5BX10 Cluster: Malic enzyme; n=1; Schistosoma
japonicum|Rep: Malic enzyme - Schistosoma japonicum
(Blood fluke)
Length = 216
Score = 126 bits (305), Expect = 3e-28
Identities = 52/91 (57%), Positives = 72/91 (79%)
Frame = +2
Query: 236 RQIRKSINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRG 415
+ + ++ +YIYL L DRNE LFY+ V ++V MP++YTPTVGLACQ++G+V+RRPRG
Sbjct: 102 KNMNDNLQRYIYLTSLQDRNEALFYKLVIEHVEYCMPLIYTPTVGLACQRYGVVFRRPRG 161
Query: 416 LFITIHDKGHVYDVLKNWPETDVRAIVVTDG 508
L+ITIHD+ H+ ++L NWPE V+AIV TDG
Sbjct: 162 LYITIHDRHHIPEILNNWPEPIVKAIVFTDG 192
Score = 38.3 bits (85), Expect = 0.15
Identities = 16/19 (84%), Positives = 18/19 (94%)
Frame = +1
Query: 508 KRILGLGDLGACGMGIPVG 564
+RILGLGDLGA GMGIP+G
Sbjct: 193 ERILGLGDLGAYGMGIPIG 211
Score = 35.5 bits (78), Expect = 1.1
Identities = 17/29 (58%), Positives = 18/29 (62%)
Frame = +3
Query: 129 GHGFYHRRASLLGIHGLLPPRVKTQEEQV 215
G F LLGIHGLLPP V T E+QV
Sbjct: 66 GTAFTVNERQLLGIHGLLPPSVLTLEQQV 94
>UniRef50_P48163 Cluster: NADP-dependent malic enzyme; n=63;
Eukaryota|Rep: NADP-dependent malic enzyme - Homo
sapiens (Human)
Length = 572
Score = 126 bits (303), Expect = 6e-28
Identities = 53/89 (59%), Positives = 69/89 (77%)
Frame = +2
Query: 242 IRKSINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLF 421
+ ++Y+ LM L DRNE LFYR + ++ + MPIVYTPTVGLACQ++ LV+R+PRGLF
Sbjct: 65 LNSDFDRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLF 124
Query: 422 ITIHDKGHVYDVLKNWPETDVRAIVVTDG 508
ITIHD+GH+ VL WPE ++AIVVTDG
Sbjct: 125 ITIHDRGHIASVLNAWPEDVIKAIVVTDG 153
Score = 70.5 bits (165), Expect = 3e-11
Identities = 30/41 (73%), Positives = 35/41 (85%)
Frame = +1
Query: 508 KRILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
+RILGLGDLG GMGIPVGKLALYTA GG+ P +CLP+ +D
Sbjct: 154 ERILGLGDLGCNGMGIPVGKLALYTACGGMNPQECLPVILD 194
>UniRef50_A2ZQ54 Cluster: Malic enzyme; n=9; Oryza sativa|Rep: Malic
enzyme - Oryza sativa subsp. japonica (Rice)
Length = 613
Score = 122 bits (294), Expect = 7e-27
Identities = 49/91 (53%), Positives = 72/91 (79%)
Frame = +2
Query: 236 RQIRKSINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRG 415
RQ + +Y+ +M L +RNE LFY+ + DNV E++P+VYTPTVG ACQK+G ++R+P+G
Sbjct: 148 RQYSVPLQRYMAMMDLQERNERLFYKLLIDNVEELLPVVYTPTVGEACQKYGSIFRQPQG 207
Query: 416 LFITIHDKGHVYDVLKNWPETDVRAIVVTDG 508
L++++ DKG V DVL+NWPE +++ IVVTDG
Sbjct: 208 LYVSLKDKGKVLDVLRNWPERNIQVIVVTDG 238
Score = 74.9 bits (176), Expect = 1e-12
Identities = 33/41 (80%), Positives = 37/41 (90%)
Frame = +1
Query: 508 KRILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
+RILGLGDLG GMGIPVGKL+LYTALGG++P CLPITID
Sbjct: 239 ERILGLGDLGCQGMGIPVGKLSLYTALGGVRPSACLPITID 279
>UniRef50_P06801 Cluster: NADP-dependent malic enzyme; n=52;
cellular organisms|Rep: NADP-dependent malic enzyme -
Mus musculus (Mouse)
Length = 572
Score = 122 bits (294), Expect = 7e-27
Identities = 53/90 (58%), Positives = 68/90 (75%)
Frame = +2
Query: 239 QIRKSINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGL 418
++ ++Y+ LM L DRNE LFY + +V + MPIVYTPTVGLACQ++ L +R+PRGL
Sbjct: 64 RLNSDFDRYLLLMDLQDRNEKLFYSVLMSDVEKFMPIVYTPTVGLACQQYSLAFRKPRGL 123
Query: 419 FITIHDKGHVYDVLKNWPETDVRAIVVTDG 508
FI+IHDKGH+ VL WPE V+AIVVTDG
Sbjct: 124 FISIHDKGHIASVLNAWPEDVVKAIVVTDG 153
Score = 75.4 bits (177), Expect = 1e-12
Identities = 33/41 (80%), Positives = 36/41 (87%)
Frame = +1
Query: 508 KRILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
+RILGLGDLG GMGIPVGKLALYTA GG+ P QCLPIT+D
Sbjct: 154 ERILGLGDLGCNGMGIPVGKLALYTACGGVNPQQCLPITLD 194
>UniRef50_A0L5P5 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=1;
Magnetococcus sp. MC-1|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Magnetococcus
sp. (strain MC-1)
Length = 556
Score = 121 bits (291), Expect = 2e-26
Identities = 51/86 (59%), Positives = 68/86 (79%)
Frame = +2
Query: 254 INKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIH 433
+ KYI+L GL +RNE LFYR V N+ EM+PI+YTPTVG ACQ +G ++RRP+G+FI+I+
Sbjct: 73 LEKYIFLTGLQERNETLFYRLVMTNIEEMLPIIYTPTVGKACQTYGHIFRRPQGMFISIN 132
Query: 434 DKGHVYDVLKNWPETDVRAIVVTDGN 511
DKG + ++L NW DVR IVVTDG+
Sbjct: 133 DKGRIAELLGNWVHKDVRVIVVTDGS 158
Score = 72.5 bits (170), Expect = 8e-12
Identities = 33/40 (82%), Positives = 35/40 (87%)
Frame = +1
Query: 511 RILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
RILGLGDLGA GMGIPVGKLALYTAL GI P CLP+T+D
Sbjct: 159 RILGLGDLGAHGMGIPVGKLALYTALAGIPPIHCLPVTLD 198
>UniRef50_Q89G76 Cluster: Malic enzyme; n=3; cellular organisms|Rep:
Malic enzyme - Bradyrhizobium japonicum
Length = 531
Score = 118 bits (283), Expect = 2e-25
Identities = 51/91 (56%), Positives = 68/91 (74%)
Frame = +2
Query: 236 RQIRKSINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRG 415
R + + KY+ L L DRNE LF+R V DN+ E+ PI+YTPTVGLACQK+GL+++RPRG
Sbjct: 48 RMLPTDLEKYVALNALHDRNEALFFRVVVDNIDEIQPIIYTPTVGLACQKYGLIFQRPRG 107
Query: 416 LFITIHDKGHVYDVLKNWPETDVRAIVVTDG 508
+FI+ D+G + ++LKNWP R IVVTDG
Sbjct: 108 MFISSRDRGQIAEILKNWP-YPARLIVVTDG 137
Score = 67.3 bits (157), Expect = 3e-10
Identities = 29/41 (70%), Positives = 34/41 (82%)
Frame = +1
Query: 508 KRILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
+RILGLGDLGA GMGIPVGKL+LY+A G+ P CLPI +D
Sbjct: 138 ERILGLGDLGANGMGIPVGKLSLYSACAGVHPEHCLPIVLD 178
>UniRef50_Q0AIF8 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=2;
Nitrosomonas|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Nitrosomonas
eutropha (strain C71)
Length = 536
Score = 118 bits (283), Expect = 2e-25
Identities = 51/91 (56%), Positives = 67/91 (73%)
Frame = +2
Query: 236 RQIRKSINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRG 415
R +I KYIYL LL+RN+ LFYR + D++ E+MP+VYTPTVG AC K ++R+P+G
Sbjct: 54 RNKSSNIEKYIYLNDLLERNQQLFYRTLVDHIGEIMPLVYTPTVGEACVKLSHIFRKPQG 113
Query: 416 LFITIHDKGHVYDVLKNWPETDVRAIVVTDG 508
+IT D+G + LKNWPETDV+ IVVTDG
Sbjct: 114 FYITPEDRGEIISRLKNWPETDVQIIVVTDG 144
Score = 64.1 bits (149), Expect = 3e-09
Identities = 26/41 (63%), Positives = 34/41 (82%)
Frame = +1
Query: 508 KRILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
+RILGLGDLGA GMGIP+GK++LY A GI P +C+P+ +D
Sbjct: 145 ERILGLGDLGANGMGIPIGKISLYVACAGIYPDRCMPVMLD 185
>UniRef50_A7CWP9 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=1;
Opitutaceae bacterium TAV2|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Opitutaceae
bacterium TAV2
Length = 561
Score = 118 bits (283), Expect = 2e-25
Identities = 54/97 (55%), Positives = 73/97 (75%), Gaps = 2/97 (2%)
Frame = +2
Query: 224 QALDRQIRK--SINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLV 397
+AL+ +K +I KYIYL L RNE LFYR + ++ EM+P+VYTPTVG AC ++G
Sbjct: 66 RALNAMAKKPSAIEKYIYLTTLQSRNETLFYRLLTNHAEEMIPLVYTPTVGQACLEYGAN 125
Query: 398 YRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDG 508
+RRPRGLFI+I D+G + ++L++WP TDVR IVVTDG
Sbjct: 126 FRRPRGLFISIKDRGRIAEILRHWPITDVRMIVVTDG 162
Score = 66.5 bits (155), Expect = 5e-10
Identities = 29/41 (70%), Positives = 33/41 (80%)
Frame = +1
Query: 508 KRILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
+RILGLGDLG GMGIPVGKLALY+A G+ P CLPI +D
Sbjct: 163 ERILGLGDLGVLGMGIPVGKLALYSACAGLHPSYCLPIALD 203
Score = 33.1 bits (72), Expect = 5.7
Identities = 15/28 (53%), Positives = 17/28 (60%)
Frame = +3
Query: 129 GHGFYHRRASLLGIHGLLPPRVKTQEEQ 212
G F R LG+ GLLPPRV T E+Q
Sbjct: 36 GTAFSERERDALGLRGLLPPRVFTLEQQ 63
>UniRef50_P16243 Cluster: NADP-dependent malic enzyme, chloroplast
precursor; n=79; Magnoliophyta|Rep: NADP-dependent malic
enzyme, chloroplast precursor - Zea mays (Maize)
Length = 636
Score = 113 bits (271), Expect = 4e-24
Identities = 45/91 (49%), Positives = 68/91 (74%)
Frame = +2
Query: 236 RQIRKSINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRG 415
RQ + + +YI +M L + +E LFY+ + DNV E++P VYTPTVG ACQK+G ++ RP+G
Sbjct: 145 RQYQTPLQRYIAMMNLQETDERLFYKLLIDNVVELLPFVYTPTVGEACQKYGSIFGRPQG 204
Query: 416 LFITIHDKGHVYDVLKNWPETDVRAIVVTDG 508
L++++ DKG V +VL+NWP +++ I VTDG
Sbjct: 205 LYVSLKDKGKVLEVLRNWPHRNIQVICVTDG 235
Score = 76.2 bits (179), Expect = 6e-13
Identities = 35/46 (76%), Positives = 37/46 (80%)
Frame = +1
Query: 493 CCNRRKRILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
C +RILGLGDLG GMGIPVGKLALYTALGG+ P CLPITID
Sbjct: 231 CVTDGERILGLGDLGCQGMGIPVGKLALYTALGGVDPSVCLPITID 276
>UniRef50_A7PC00 Cluster: Chromosome chr2 scaffold_11, whole genome
shotgun sequence; n=3; Vitis vinifera|Rep: Chromosome
chr2 scaffold_11, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 573
Score = 109 bits (262), Expect = 5e-23
Identities = 45/91 (49%), Positives = 66/91 (72%)
Frame = +2
Query: 236 RQIRKSINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRG 415
RQ + + +Y+ +M +RNE LFY+ + DNV E++P+VYTPTVG ACQK+G ++RRP+
Sbjct: 245 RQYKVPLQRYMAMMDFQERNERLFYKLLIDNVEELLPVVYTPTVGEACQKYGSIFRRPQS 304
Query: 416 LFITIHDKGHVYDVLKNWPETDVRAIVVTDG 508
L+I G + +VLKNWPE ++ IVVT+G
Sbjct: 305 LYIIDFFMGKILEVLKNWPERSIQVIVVTNG 335
Score = 70.9 bits (166), Expect = 2e-11
Identities = 31/41 (75%), Positives = 35/41 (85%)
Frame = +1
Query: 508 KRILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
+RILGLGDLG GMGIPVGKL+LYT LGG+ P CLP+TID
Sbjct: 336 ERILGLGDLGCQGMGIPVGKLSLYTTLGGLHPSVCLPVTID 376
>UniRef50_Q016K2 Cluster: NADP dependent malic enzyme; n=2;
Ostreococcus|Rep: NADP dependent malic enzyme -
Ostreococcus tauri
Length = 641
Score = 107 bits (257), Expect = 2e-22
Identities = 43/91 (47%), Positives = 68/91 (74%)
Frame = +2
Query: 236 RQIRKSINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRG 415
R++ + K+ +L L +RNE LFYR V D++ E++P++ PTV C++ GL+YR+PRG
Sbjct: 131 RRVTSGVEKHAWLPALYERNERLFYRVVKDHLEELLPVLAEPTVWQVCREAGLMYRQPRG 190
Query: 416 LFITIHDKGHVYDVLKNWPETDVRAIVVTDG 508
L++++ DKG VY +LKNWP +V+A+V+TDG
Sbjct: 191 LYVSMQDKGSVYRLLKNWPVRNVKAVVLTDG 221
Score = 49.2 bits (112), Expect = 8e-05
Identities = 22/41 (53%), Positives = 28/41 (68%)
Frame = +1
Query: 508 KRILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
+R+ G+GDLG GM V K +L+TALGG+ P LPI ID
Sbjct: 222 QRVTGIGDLGVQGMPAAVSKASLFTALGGLDPADVLPICID 262
>UniRef50_A6SA55 Cluster: Malic enzyme; n=2; Sclerotiniaceae|Rep:
Malic enzyme - Botryotinia fuckeliana B05.10
Length = 685
Score = 101 bits (243), Expect = 1e-20
Identities = 40/86 (46%), Positives = 64/86 (74%)
Frame = +2
Query: 254 INKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIH 433
I KY+YL L + N HLFYR V +++ ++ P++YTPTVG AC ++ +Y++P GL+++ H
Sbjct: 144 IEKYMYLSNLRNNNVHLFYRLVQEHLTDITPLIYTPTVGEACLRWSEIYQQPEGLYLSYH 203
Query: 434 DKGHVYDVLKNWPETDVRAIVVTDGN 511
D+G++ +VL NW ++DV VVTDG+
Sbjct: 204 DRGNLEEVLGNWRQSDVEMTVVTDGS 229
Score = 63.7 bits (148), Expect = 4e-09
Identities = 29/40 (72%), Positives = 32/40 (80%)
Frame = +1
Query: 511 RILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
RILGLGDLG GMGIPVGKL+LYT GI P + LPIT+D
Sbjct: 230 RILGLGDLGVNGMGIPVGKLSLYTGCAGIHPSKTLPITLD 269
>UniRef50_Q8D911 Cluster: NAD-dependent malic enzyme; n=187;
cellular organisms|Rep: NAD-dependent malic enzyme -
Vibrio vulnificus
Length = 562
Score = 100 bits (239), Expect = 3e-20
Identities = 43/91 (47%), Positives = 62/91 (68%)
Frame = +2
Query: 236 RQIRKSINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRG 415
+ ++K+IYL + D NE LFYR V +++ EMMPI+YTPTVG AC+ F +YRR RG
Sbjct: 62 KAFESDMDKHIYLRNIQDTNETLFYRLVQNHITEMMPIIYTPTVGAACENFSNIYRRGRG 121
Query: 416 LFITIHDKGHVYDVLKNWPETDVRAIVVTDG 508
LF++ ++ + D+L N +V+ IVVTDG
Sbjct: 122 LFVSYANRDRIDDILNNASNHNVKVIVVTDG 152
Score = 62.1 bits (144), Expect = 1e-08
Identities = 28/41 (68%), Positives = 32/41 (78%)
Frame = +1
Query: 508 KRILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
+RILGLGD G GMGIP+GKL+LYTA GGI P LPI +D
Sbjct: 153 ERILGLGDQGIGGMGIPIGKLSLYTACGGISPAYTLPIVLD 193
>UniRef50_Q8I8I4 Cluster: Malic enzyme; n=4; Eukaryota|Rep: Malic
enzyme - Mastigamoeba balamuthi (Phreatamoeba balamuthi)
Length = 568
Score = 98.3 bits (234), Expect = 1e-19
Identities = 45/83 (54%), Positives = 57/83 (68%)
Frame = +2
Query: 260 KYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 439
KY+YL L RN+ LF+ V +V E +P+VYTPTVG C KF +R P GL+IT DK
Sbjct: 91 KYLYLSQLSQRNQTLFFYLVQHHVEECVPLVYTPTVGEGCTKFSAEFRNPTGLYITPEDK 150
Query: 440 GHVYDVLKNWPETDVRAIVVTDG 508
GHV ++L+NWP +V IVVTDG
Sbjct: 151 GHVAEILENWPH-EVEIIVVTDG 172
Score = 59.3 bits (137), Expect = 8e-08
Identities = 26/40 (65%), Positives = 31/40 (77%)
Frame = +1
Query: 511 RILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
RILGLGDLG+ GMGIP+GKL LY A G +P + LP+ ID
Sbjct: 174 RILGLGDLGSNGMGIPIGKLHLYIACAGFRPDRTLPVMID 213
>UniRef50_UPI0000D9F768 Cluster: PREDICTED: similar to Y48B6A.12,
partial; n=1; Macaca mulatta|Rep: PREDICTED: similar to
Y48B6A.12, partial - Macaca mulatta
Length = 456
Score = 97.9 bits (233), Expect = 2e-19
Identities = 46/91 (50%), Positives = 61/91 (67%)
Frame = +2
Query: 239 QIRKSINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGL 418
Q I KYIYL L DRNE L+++ + D+VAEMMPIVYTP VG ACQ FG ++R RGL
Sbjct: 56 QNSNDIEKYIYLESLHDRNETLYFKLLVDHVAEMMPIVYTPVVGKACQLFGHIFRNARGL 115
Query: 419 FITIHDKGHVYDVLKNWPETDVRAIVVTDGN 511
+ + +KG+ +++ N D IVVTDG+
Sbjct: 116 YFNLSEKGNFKEMVWNSNVRDADIIVVTDGS 146
Score = 61.3 bits (142), Expect = 2e-08
Identities = 26/40 (65%), Positives = 32/40 (80%)
Frame = +1
Query: 511 RILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
RILGLGDLG GMGIP+GKL+LY A GI P + +P+T+D
Sbjct: 147 RILGLGDLGTNGMGIPIGKLSLYVACAGINPGRTVPVTLD 186
>UniRef50_A7IMB8 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=2;
Alphaproteobacteria|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Xanthobacter
sp. (strain Py2)
Length = 550
Score = 97.9 bits (233), Expect = 2e-19
Identities = 41/89 (46%), Positives = 62/89 (69%)
Frame = +2
Query: 242 IRKSINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLF 421
++ +++Y YLM L RNE +FY+ V + +PI+Y PTV AC+ FG +YRRPRG++
Sbjct: 69 VKDELDQYSYLMDLEARNETVFYKAVMSDPKRFIPILYDPTVADACEAFGNLYRRPRGMY 128
Query: 422 ITIHDKGHVYDVLKNWPETDVRAIVVTDG 508
IT H KG + +VL+NWP+ D+R + V+ G
Sbjct: 129 ITRHMKGRMAEVLRNWPQKDIRFVCVSTG 157
Score = 58.8 bits (136), Expect = 1e-07
Identities = 26/46 (56%), Positives = 31/46 (67%)
Frame = +1
Query: 493 CCNRRKRILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
C + RILGLGD+GA GMGIP+GKL LYTA + P LP+ D
Sbjct: 153 CVSTGGRILGLGDIGANGMGIPIGKLQLYTACAAVPPDVLLPVLFD 198
Score = 32.3 bits (70), Expect = 10.0
Identities = 16/38 (42%), Positives = 20/38 (52%)
Frame = +1
Query: 76 PTSGLSGLDHLKHPGLNKGMAFTIEERHSWAYTGCYHH 189
P S LSGL+ L P NKG A+T ++R G H
Sbjct: 13 PKSNLSGLNLLHDPVRNKGTAYTRDDRRQLGLEGLLPH 50
>UniRef50_A3QW96 Cluster: Malic enzyme; n=10; Tigriopus
californicus|Rep: Malic enzyme - Tigriopus californicus
(Marine copepod)
Length = 322
Score = 97.5 bits (232), Expect = 2e-19
Identities = 41/87 (47%), Positives = 59/87 (67%)
Frame = +2
Query: 251 SINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITI 430
+I K+ L + DRNE LFYR + DN +M PI+YTPTVG AC F +YRRPRG++ +
Sbjct: 117 NIRKWKVLQSVQDRNETLFYRILMDNFQDMAPIIYTPTVGWACSHFSQLYRRPRGMYFSH 176
Query: 431 HDKGHVYDVLKNWPETDVRAIVVTDGN 511
D+G + ++ NW +V A+V+TDG+
Sbjct: 177 GDRGEMASMVYNWESDEVDAVVITDGS 203
Score = 55.6 bits (128), Expect = 9e-07
Identities = 24/40 (60%), Positives = 29/40 (72%)
Frame = +1
Query: 511 RILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
RILGLGDLG G+GI +GKL LY A GG P + LP+ +D
Sbjct: 204 RILGLGDLGLGGLGISIGKLDLYVAAGGFHPRRVLPVVLD 243
>UniRef50_Q86NT5 Cluster: Malic enzyme; n=2; Drosophila
melanogaster|Rep: Malic enzyme - Drosophila melanogaster
(Fruit fly)
Length = 610
Score = 96.7 bits (230), Expect = 4e-19
Identities = 42/87 (48%), Positives = 60/87 (68%), Gaps = 1/87 (1%)
Frame = +2
Query: 251 SINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITI 430
++ +Y YL L E L+++FV+ NV ++PI+YTPTVGLAC +G++YR G+ IT
Sbjct: 99 NVGRYRYLRALRQGYERLYFQFVSKNVHAVLPIIYTPTVGLACTVYGMLYRGMTGIHITK 158
Query: 431 HDKGHVYDVLKNWP-ETDVRAIVVTDG 508
HD+GH+ +L NWP V+AI VTDG
Sbjct: 159 HDRGHMKQILSNWPMRRSVKAICVTDG 185
Score = 63.3 bits (147), Expect = 5e-09
Identities = 30/46 (65%), Positives = 33/46 (71%)
Frame = +1
Query: 493 CCNRRKRILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
C +RILGLGDLGA GMGI VGK+ LYTAL GI P LPI +D
Sbjct: 181 CVTDGQRILGLGDLGANGMGIAVGKMELYTALAGIPPSMLLPICLD 226
>UniRef50_Q4X1Z2 Cluster: NADP-dependent malic enzyme MaeA; n=11;
Pezizomycotina|Rep: NADP-dependent malic enzyme MaeA -
Aspergillus fumigatus (Sartorya fumigata)
Length = 661
Score = 96.7 bits (230), Expect = 4e-19
Identities = 37/87 (42%), Positives = 62/87 (71%)
Frame = +2
Query: 251 SINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITI 430
+I+K++YL L N HLFYR V D++ E+ P++YTP VG ACQK+ +Y++P G++++
Sbjct: 135 AIDKFLYLSTLRKNNVHLFYRLVTDHLKELTPLIYTPVVGEACQKWSEIYQQPEGMYLSW 194
Query: 431 HDKGHVYDVLKNWPETDVRAIVVTDGN 511
D+G++ V+ NWP+ +V +TDG+
Sbjct: 195 EDRGNLAAVIANWPQPNVEITCITDGS 221
Score = 67.3 bits (157), Expect = 3e-10
Identities = 30/46 (65%), Positives = 34/46 (73%)
Frame = +1
Query: 493 CCNRRKRILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
C RILGLGDLG GMGIP+GKLALYTA GI+P LP+T+D
Sbjct: 216 CITDGSRILGLGDLGINGMGIPIGKLALYTACAGIRPEATLPLTLD 261
>UniRef50_P37221 Cluster: NAD-dependent malic enzyme 62 kDa isoform,
mitochondrial precursor; n=41; Eukaryota|Rep:
NAD-dependent malic enzyme 62 kDa isoform, mitochondrial
precursor - Solanum tuberosum (Potato)
Length = 626
Score = 95.5 bits (227), Expect = 9e-19
Identities = 41/84 (48%), Positives = 58/84 (69%)
Frame = +2
Query: 260 KYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 439
K+ L L DRNE L+Y+ + +N+ E PIVYTPTVGL CQK+ ++RRPRG++ + D+
Sbjct: 115 KWRILNRLHDRNETLYYKVLMENIEEYAPIVYTPTVGLVCQKYSGLFRRPRGMYFSAEDR 174
Query: 440 GHVYDVLKNWPETDVRAIVVTDGN 511
G + ++ NWP V IVVTDG+
Sbjct: 175 GEMMSMVYNWPADQVDMIVVTDGS 198
Score = 55.2 bits (127), Expect = 1e-06
Identities = 25/40 (62%), Positives = 29/40 (72%)
Frame = +1
Query: 511 RILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
RILGLGDLG G+GI +GKL LY A GI P + LP+ ID
Sbjct: 199 RILGLGDLGIQGIGIAIGKLDLYVAAAGINPQRVLPVMID 238
>UniRef50_P78715 Cluster: Malic enzyme, hydrogenosomal precursor;
n=1; Neocallimastix frontalis|Rep: Malic enzyme,
hydrogenosomal precursor - Neocallimastix frontalis
(Rumen fungus)
Length = 592
Score = 95.5 bits (227), Expect = 9e-19
Identities = 41/91 (45%), Positives = 60/91 (65%)
Frame = +2
Query: 239 QIRKSINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGL 418
+I + K+IYL L +RNE L+Y+ + +N E+ PI+YTP VG ACQKF ++ + RG+
Sbjct: 96 KISDPLEKFIYLNHLQNRNETLYYKMILENFVELAPIIYTPVVGEACQKFHKIFTQTRGM 155
Query: 419 FITIHDKGHVYDVLKNWPETDVRAIVVTDGN 511
+ + D+G + V NWP DV IVVTDG+
Sbjct: 156 YFSTADRGQMSAVAANWPYDDVDVIVVTDGS 186
Score = 58.8 bits (136), Expect = 1e-07
Identities = 27/40 (67%), Positives = 29/40 (72%)
Frame = +1
Query: 511 RILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
RILGLGDLGA GM IP+GKL LY GGI P LPI +D
Sbjct: 187 RILGLGDLGAGGMQIPIGKLTLYVCGGGINPRNVLPIVLD 226
Score = 38.7 bits (86), Expect = 0.11
Identities = 17/43 (39%), Positives = 25/43 (58%)
Frame = +3
Query: 129 GHGFYHRRASLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPL 257
G F LGI GL+PPR ++ E Q + CK ++D+ +PL
Sbjct: 59 GSAFTADEKDRLGIRGLVPPRPQSLEAQYKRCKTNLDKISDPL 101
>UniRef50_A1ZAF7 Cluster: Malic enzyme; n=5; Sophophora|Rep: Malic
enzyme - Drosophila melanogaster (Fruit fly)
Length = 603
Score = 93.1 bits (221), Expect = 5e-18
Identities = 39/85 (45%), Positives = 59/85 (69%)
Frame = +2
Query: 254 INKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIH 433
I ++ YL + R+ L+YRF+ +N+ + +PIVYTPTVG +GL +++ LFI+IH
Sbjct: 92 IARFTYLSAVHHRHRRLYYRFIKENIEKSLPIVYTPTVGDVVATYGLNFQQAISLFISIH 151
Query: 434 DKGHVYDVLKNWPETDVRAIVVTDG 508
DKGH+ D++ NW + V+AI VTDG
Sbjct: 152 DKGHIRDLMHNWVDEGVKAICVTDG 176
Score = 56.0 bits (129), Expect = 7e-07
Identities = 25/52 (48%), Positives = 33/52 (63%)
Frame = +1
Query: 475 DGRPCHCCNRRKRILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
+G C R+LGLGD+GA MGI +GK+ LYTALG I P +P+ +D
Sbjct: 166 EGVKAICVTDGGRVLGLGDMGANAMGISLGKMILYTALGSIPPSTLMPVCLD 217
>UniRef50_Q00XN9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
enzyme - Ostreococcus tauri
Length = 639
Score = 92.7 bits (220), Expect = 7e-18
Identities = 41/95 (43%), Positives = 64/95 (67%)
Frame = +2
Query: 227 ALDRQIRKSINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRR 406
A ++ + + ++K+ +L L DRNE LFYR V D++ E+ PI+YTPTVG AC F + RR
Sbjct: 126 AQNQSLERPLDKWQHLQDLKDRNETLFYRLVHDHIEELAPIIYTPTVGDACLNFSKLLRR 185
Query: 407 PRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGN 511
RG++ ++ D+G + ++ NW + V IVVTDG+
Sbjct: 186 ARGMYFSVDDRGDINSMMFNW-KRSVSVIVVTDGS 219
Score = 52.4 bits (120), Expect = 9e-06
Identities = 24/40 (60%), Positives = 27/40 (67%)
Frame = +1
Query: 511 RILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
RILGLGDLG GMGI GK+ LY A GG P LP+ +D
Sbjct: 220 RILGLGDLGTNGMGISQGKVDLYVAGGGFDPQHVLPVVLD 259
>UniRef50_Q01AM5 Cluster: NADP+-dependent malic enzyme; n=2;
Ostreococcus|Rep: NADP+-dependent malic enzyme -
Ostreococcus tauri
Length = 580
Score = 90.2 bits (214), Expect = 4e-17
Identities = 39/90 (43%), Positives = 57/90 (63%)
Frame = +2
Query: 239 QIRKSINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGL 418
Q KY L+ L +E FYR + ++PI+YTPTVG AC KFG + +RP GL
Sbjct: 95 QCETPFEKYKQLVALQMTDESTFYRMLRSQTETLLPILYTPTVGEACVKFGTLVQRPMGL 154
Query: 419 FITIHDKGHVYDVLKNWPETDVRAIVVTDG 508
+++ +D G+V +++NWP TDV+ V+TDG
Sbjct: 155 WVSSNDAGNVKQLIRNWPATDVKIAVITDG 184
Score = 46.0 bits (104), Expect = 8e-04
Identities = 23/41 (56%), Positives = 27/41 (65%)
Frame = +1
Query: 508 KRILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
+RILGLGD GA GMGI GK +Y A G+ P LPI +D
Sbjct: 185 ERILGLGDQGANGMGISAGKSMVYAAC-GVPPSALLPIQVD 224
>UniRef50_Q9HE50 Cluster: Malic enzyme; n=6; Pezizomycotina|Rep:
Malic enzyme - Neurospora crassa
Length = 1023
Score = 89.0 bits (211), Expect = 8e-17
Identities = 41/123 (33%), Positives = 67/123 (54%)
Frame = +2
Query: 143 PSKSVTLGHTRVVTTTSQDARGAG*TMQALDRQIRKSINKYIYLMGLLDRNEHLFYRFVA 322
P + V T ++ +D+ + R + I++Y+YL + +N LFYR +
Sbjct: 489 PEERVAKNLTGLIPHVMEDSEKQVERALKMIRTRQTDIDRYLYLSTIKSQNVDLFYRLLM 548
Query: 323 DNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVT 502
D+ EMMP+VYTPT+G C ++ +Y RP L+I+I + + +L+NWP VVT
Sbjct: 549 DHAKEMMPLVYTPTIGDVCLQYSTLYTRPEALYISIKQRKSIRTILRNWPYPQPEICVVT 608
Query: 503 DGN 511
DG+
Sbjct: 609 DGS 611
Score = 62.5 bits (145), Expect = 8e-09
Identities = 28/40 (70%), Positives = 32/40 (80%)
Frame = +1
Query: 511 RILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
RILGLGDLG G+GIP+GKLALYTA GI P + LPI +D
Sbjct: 612 RILGLGDLGVNGVGIPIGKLALYTAAAGIHPDKTLPIVLD 651
>UniRef50_A3BK03 Cluster: Malic enzyme; n=2; Oryza sativa|Rep: Malic
enzyme - Oryza sativa subsp. japonica (Rice)
Length = 635
Score = 88.6 bits (210), Expect = 1e-16
Identities = 40/86 (46%), Positives = 57/86 (66%), Gaps = 2/86 (2%)
Frame = +2
Query: 260 KYIYLMGLLDRNEHLFYR--FVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIH 433
K+ L L DRNE ++Y+ + DN+ E PIVYTPTVGL CQ + ++RRPRG++ +
Sbjct: 147 KWRILNRLHDRNETMYYKAEVLIDNIEEHAPIVYTPTVGLVCQNYSGLFRRPRGMYFSAE 206
Query: 434 DKGHVYDVLKNWPETDVRAIVVTDGN 511
D+G + ++ NWP V IVVTDG+
Sbjct: 207 DRGEMMSMVYNWPADQVDMIVVTDGS 232
Score = 55.6 bits (128), Expect = 9e-07
Identities = 25/40 (62%), Positives = 29/40 (72%)
Frame = +1
Query: 511 RILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
RILGLGDLG G+GI +GKL LY A GI P + LP+ ID
Sbjct: 233 RILGLGDLGVHGIGIAIGKLDLYVAAAGINPQRVLPVMID 272
>UniRef50_Q4PC56 Cluster: Malic enzyme; n=1; Ustilago maydis|Rep:
Malic enzyme - Ustilago maydis (Smut fungus)
Length = 634
Score = 88.2 bits (209), Expect = 1e-16
Identities = 38/88 (43%), Positives = 56/88 (63%), Gaps = 2/88 (2%)
Frame = +2
Query: 254 INKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIH 433
+ K++ L L N L+Y + N E++P++YTPTVG ACQKF +YRRP GL I++
Sbjct: 131 LEKHVMLASLRQTNTRLYYATILANKEEILPLIYTPTVGEACQKFSHIYRRPEGLSISLE 190
Query: 434 DKGHVYDVLKNW--PETDVRAIVVTDGN 511
DKG + +++NW P R V+TDG+
Sbjct: 191 DKGKIASIVENWPVPAGSPRIAVITDGS 218
Score = 53.2 bits (122), Expect = 5e-06
Identities = 25/40 (62%), Positives = 28/40 (70%)
Frame = +1
Query: 511 RILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
RILGLGDLG G GI +GKL+LY A GI P LPI +D
Sbjct: 219 RILGLGDLGWNGQGISIGKLSLYVAGAGIHPRATLPIVVD 258
>UniRef50_Q9RYN4 Cluster: Malate oxidoreductase; n=6;
Deinococci|Rep: Malate oxidoreductase - Deinococcus
radiodurans
Length = 580
Score = 87.8 bits (208), Expect = 2e-16
Identities = 44/101 (43%), Positives = 58/101 (57%)
Frame = +2
Query: 251 SINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITI 430
++ K++YL L DRNE LFY ++ +V EM+PIVYTPTVG A +KF +YR PRGL ++
Sbjct: 90 ALEKHVYLRNLQDRNEVLFYALLSHHVEEMLPIVYTPTVGDAVKKFSQIYRYPRGLTLST 149
Query: 431 HDKGHVYDVLKNWPETDVRAIVVTDGNVFWVLATWAHAGWA 553
L N P DVR IV TD + + G A
Sbjct: 150 RTIERAEQALANVPLNDVRIIVATDSSAILGIGDQGFGGMA 190
Score = 50.4 bits (115), Expect = 4e-05
Identities = 21/39 (53%), Positives = 28/39 (71%)
Frame = +1
Query: 514 ILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
ILG+GD G GM I +GKL+LYT GG+ P + LP+ +D
Sbjct: 178 ILGIGDQGFGGMAISIGKLSLYTVAGGVGPDKTLPVELD 216
>UniRef50_Q875H8 Cluster: Malic enzyme; n=1; Mucor
circinelloides|Rep: Malic enzyme - Mucor circinelloides
Length = 617
Score = 87.8 bits (208), Expect = 2e-16
Identities = 37/84 (44%), Positives = 57/84 (67%)
Frame = +2
Query: 260 KYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 439
K+++L L DRNE L+Y+ + +++ E+ I+YTPTVGLA Q +YRR RG++ + D+
Sbjct: 106 KFVFLAALHDRNETLYYKIIMEHLEELAGIIYTPTVGLASQMSHSIYRRSRGMYFSSQDR 165
Query: 440 GHVYDVLKNWPETDVRAIVVTDGN 511
G + ++ NWP V IVVTDG+
Sbjct: 166 GQMSAMVYNWPHDKVDVIVVTDGS 189
Score = 61.7 bits (143), Expect = 1e-08
Identities = 26/40 (65%), Positives = 32/40 (80%)
Frame = +1
Query: 511 RILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
R+LGLGDLGA GM IP+GKL+LY A GGI+P LP+ +D
Sbjct: 190 RVLGLGDLGANGMEIPIGKLSLYVAAGGIRPRAVLPVVLD 229
>UniRef50_A0Q531 Cluster: NAD-dependent malic enzyme; n=10;
Francisella tularensis|Rep: NAD-dependent malic enzyme -
Francisella tularensis subsp. novicida (strain U112)
Length = 604
Score = 87.4 bits (207), Expect = 3e-16
Identities = 39/86 (45%), Positives = 57/86 (66%)
Frame = +2
Query: 251 SINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITI 430
S+ KY++L L D N LFY FV +N+ E+MPI+YTPTVG A QK+ +R+ GLFI+I
Sbjct: 80 SLEKYVFLNRLHDLNTTLFYHFVRENLEEIMPIIYTPTVGEAVQKYSSSFRKQSGLFISI 139
Query: 431 HDKGHVYDVLKNWPETDVRAIVVTDG 508
K H+ +L+ + + ++VTDG
Sbjct: 140 SHKKHIARILERYEYNSIDLVLVTDG 165
Score = 45.2 bits (102), Expect = 0.001
Identities = 18/39 (46%), Positives = 26/39 (66%)
Frame = +1
Query: 514 ILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
+LG+GD G GM I +GK+ +Y A GI P + LP+ +D
Sbjct: 168 VLGIGDQGIGGMNISIGKIMVYVAASGIDPARVLPVQLD 206
>UniRef50_A4RQC9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
enzyme - Ostreococcus lucimarinus CCE9901
Length = 549
Score = 87.4 bits (207), Expect = 3e-16
Identities = 39/87 (44%), Positives = 57/87 (65%)
Frame = +2
Query: 248 KSINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFIT 427
+ +N+YI+L L +NE LFYR + +++ ++MPIVYTPTVG AC F +YR G++ +
Sbjct: 61 EDMNRYIFLENLHMQNERLFYRVLVEHLEDLMPIVYTPTVGEACINFDALYRNRCGMYFS 120
Query: 428 IHDKGHVYDVLKNWPETDVRAIVVTDG 508
D G + +L NWP + IVVTDG
Sbjct: 121 RLDSGVMRRMLDNWPSPETEIIVVTDG 147
Score = 52.4 bits (120), Expect = 9e-06
Identities = 22/40 (55%), Positives = 29/40 (72%)
Frame = +1
Query: 511 RILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
R+LGLGDLG GM I VGK++LY A GG P + +P+ +D
Sbjct: 149 RVLGLGDLGTNGMAISVGKVSLYVASGGFDPAKSMPVCLD 188
>UniRef50_A2EKE3 Cluster: Malic enzyme; n=14; Trichomonadidae|Rep:
Malic enzyme - Trichomonas vaginalis G3
Length = 567
Score = 83.0 bits (196), Expect = 5e-15
Identities = 39/83 (46%), Positives = 55/83 (66%), Gaps = 1/83 (1%)
Frame = +2
Query: 260 KYIYLMGLLDRNEHLFYRFVADNVAE-MMPIVYTPTVGLACQKFGLVYRRPRGLFITIHD 436
KYI+L ++N F+RF+ + E MPI+YTPTVG ACQK+ + RG++IT D
Sbjct: 80 KYIFLANEREKNSQSFWRFLFTHPPEETMPILYTPTVGEACQKWATHRQSYRGIYITPED 139
Query: 437 KGHVYDVLKNWPETDVRAIVVTD 505
G + D+L+N+P D+R IVVTD
Sbjct: 140 SGKIKDILRNYPRQDIRCIVVTD 162
Score = 62.5 bits (145), Expect = 8e-09
Identities = 27/40 (67%), Positives = 32/40 (80%)
Frame = +1
Query: 511 RILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
RILGLGDLGA G+GIPVGKL LYT +G + P Q LP+ +D
Sbjct: 165 RILGLGDLGASGLGIPVGKLMLYTLIGQVDPDQTLPVQLD 204
>UniRef50_A1SVL3 Cluster: Malic enzyme aka malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=4;
Gammaproteobacteria|Rep: Malic enzyme aka malate
dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)) -
Psychromonas ingrahamii (strain 37)
Length = 571
Score = 82.6 bits (195), Expect = 7e-15
Identities = 39/84 (46%), Positives = 54/84 (64%)
Frame = +2
Query: 254 INKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIH 433
I KY YL L DRNE LFY ++ N+ EM PI+YTPTVG ACQ+F ++ RGL++T
Sbjct: 78 IEKYQYLRALQDRNETLFYALISRNIEEMTPIIYTPTVGKACQEFSHRFQIARGLYLTTD 137
Query: 434 DKGHVYDVLKNWPETDVRAIVVTD 505
+ V + + + D++ IVVTD
Sbjct: 138 NIHDVGSMAREFTGKDIQIIVVTD 161
Score = 57.2 bits (132), Expect = 3e-07
Identities = 24/39 (61%), Positives = 29/39 (74%)
Frame = +1
Query: 514 ILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
ILG+GD G GMGIP+GKL+LYT GI P C+PI +D
Sbjct: 165 ILGIGDQGVGGMGIPIGKLSLYTLGAGIHPDHCMPIALD 203
>UniRef50_Q4QAQ6 Cluster: Malic enzyme, putative; n=20;
Trypanosomatidae|Rep: Malic enzyme, putative -
Leishmania major
Length = 573
Score = 77.4 bits (182), Expect = 3e-13
Identities = 33/91 (36%), Positives = 59/91 (64%)
Frame = +2
Query: 239 QIRKSINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGL 418
+ + IN+Y L + + N L+Y + + + +PIVYTPTVG ACQ++G +Y++ GL
Sbjct: 68 RFNEPINRYQLLRNVQNTNVTLYYAILTRYLKQTLPIVYTPTVGEACQRYGDLYQKDHGL 127
Query: 419 FITIHDKGHVYDVLKNWPETDVRAIVVTDGN 511
++ + KG V +++N +T++ IV+TDG+
Sbjct: 128 YLDVASKGKVRRLIQNLRKTNIDVIVITDGS 158
Score = 58.0 bits (134), Expect = 2e-07
Identities = 24/40 (60%), Positives = 32/40 (80%)
Frame = +1
Query: 511 RILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
RILGLGDLG+ G+GI +GK +LY A GG+KP + LP+ +D
Sbjct: 159 RILGLGDLGSNGIGISIGKCSLYVAAGGVKPSRVLPVVMD 198
Score = 34.3 bits (75), Expect = 2.5
Identities = 16/49 (32%), Positives = 26/49 (53%)
Frame = +3
Query: 129 GHGFYHRRASLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLTSTSIL 275
G F S + + GLLPP V+T ++QVE ++R+ P+ +L
Sbjct: 31 GTAFTAAERSHMNVEGLLPPSVETLDDQVERYWDQLNRFNEPINRYQLL 79
>UniRef50_P45868 Cluster: Probable NAD-dependent malic enzyme 2;
n=37; Bacteria|Rep: Probable NAD-dependent malic enzyme
2 - Bacillus subtilis
Length = 582
Score = 77.4 bits (182), Expect = 3e-13
Identities = 43/125 (34%), Positives = 70/125 (56%), Gaps = 2/125 (1%)
Frame = +2
Query: 179 VTTTSQDARGAG*TMQALDRQIRKSINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYT 358
V + Q A+ A QA ++R+++ YL L +RNE LFY+ + +++ EM+P+VYT
Sbjct: 68 VLSLDQQAQRAYEQFQAQPDRLRQNV----YLSDLANRNEVLFYKLLKNHLREMLPVVYT 123
Query: 359 PTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPET--DVRAIVVTDGNVFWVLAT 532
PTVG A Q++ YRRP+G++++I + + +N T D+ IV TD +
Sbjct: 124 PTVGEAIQEYSHEYRRPQGIYLSIDNIDGIEKAFENLHATAGDIDLIVATDSESILGIGD 183
Query: 533 WAHAG 547
W G
Sbjct: 184 WGVGG 188
Score = 49.2 bits (112), Expect = 8e-05
Identities = 20/39 (51%), Positives = 28/39 (71%)
Frame = +1
Query: 514 ILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
ILG+GD G G+ I +GKLA+YTA GI P + +P+ +D
Sbjct: 178 ILGIGDWGVGGINIAIGKLAVYTAAAGIDPSRVIPVVLD 216
>UniRef50_Q7SHJ8 Cluster: Malic enzyme; n=12; Pezizomycotina|Rep:
Malic enzyme - Neurospora crassa
Length = 611
Score = 73.3 bits (172), Expect = 4e-12
Identities = 40/108 (37%), Positives = 65/108 (60%), Gaps = 12/108 (11%)
Frame = +2
Query: 221 MQALDRQIRKSINKYI----------YLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVG 370
+Q+L++Q++++ +Y ++ + ++NE LFYR + D++ EM +VYTPT G
Sbjct: 68 IQSLEQQVQRAYEQYCSQPNDLAKNTFMTSMKEQNEVLFYRLLHDHLDEMFSVVYTPTEG 127
Query: 371 LACQKFGLVYRRPRGLFITIHDKGHVYDVLKNW--PETDVRAIVVTDG 508
A Q + ++RRP G+F+ I+D V L W PE D+ IVVTDG
Sbjct: 128 EAIQNYSRLFRRPEGVFLNINDMDSVKRDLAQWGKPE-DIDYIVVTDG 174
Score = 44.0 bits (99), Expect = 0.003
Identities = 19/41 (46%), Positives = 27/41 (65%)
Frame = +1
Query: 508 KRILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
+ ILG+GD G G+ I + KL L T GGI P++ LP+ +D
Sbjct: 175 EEILGIGDQGCGGILISIAKLVLMTICGGIHPNRVLPVVLD 215
Score = 33.1 bits (72), Expect = 5.7
Identities = 18/39 (46%), Positives = 19/39 (48%)
Frame = +1
Query: 61 SGDGQPTSGLSGLDHLKHPGLNKGMAFTIEERHSWAYTG 177
S G L G L HP NKG AFT EER +A G
Sbjct: 24 STSGPLECALKGTVLLNHPYFNKGSAFTKEERRDFALHG 62
>UniRef50_Q5K758 Cluster: Malic enzyme; n=1; Filobasidiella
neoformans|Rep: Malic enzyme - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 600
Score = 72.5 bits (170), Expect = 8e-12
Identities = 33/87 (37%), Positives = 54/87 (62%), Gaps = 3/87 (3%)
Frame = +2
Query: 260 KYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 439
K+++L + + +LF+ + D + E+ PIVYTPTVG ACQK+ +Y P GL++ I DK
Sbjct: 107 KHVHLSKIRREDPNLFFSVMRDELTELAPIVYTPTVGEACQKYSQIYSGPEGLYLNIEDK 166
Query: 440 GHVYDVLKNWPETDV---RAIVVTDGN 511
+ ++L + V + +VVTDG+
Sbjct: 167 DRIPEILHQYASKLVAPPQILVVTDGS 193
Score = 63.7 bits (148), Expect = 4e-09
Identities = 28/40 (70%), Positives = 31/40 (77%)
Frame = +1
Query: 511 RILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
RILGLGDLG GMGI VGKL LY A GG+ PH CLP+ +D
Sbjct: 194 RILGLGDLGIGGMGISVGKLNLYVAGGGVNPHGCLPVVLD 233
>UniRef50_A3YYQ0 Cluster: Malate oxidoreductase; n=1; Synechococcus
sp. WH 5701|Rep: Malate oxidoreductase - Synechococcus
sp. WH 5701
Length = 517
Score = 70.1 bits (164), Expect = 4e-11
Identities = 35/89 (39%), Positives = 52/89 (58%), Gaps = 1/89 (1%)
Frame = +2
Query: 242 IRKSINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPR-GL 418
+R + ++ + + L N LF+RF+AD++ +MPIVYTPTVG A Q+F L YR P G+
Sbjct: 18 LRNDLERFRFAVALRQANLTLFHRFLADHIEAVMPIVYTPTVGAAIQRFSLDYRTPSGGV 77
Query: 419 FITIHDKGHVYDVLKNWPETDVRAIVVTD 505
F+ D + VL V I++TD
Sbjct: 78 FLAAPDLERIESVLSQAATGPVDLILITD 106
Score = 43.6 bits (98), Expect = 0.004
Identities = 19/39 (48%), Positives = 27/39 (69%)
Frame = +1
Query: 514 ILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
ILG+GD G G+ I +GKLA+YT G+ P + LP+ +D
Sbjct: 110 ILGIGDQGIGGIEICLGKLAVYTLCAGLDPARVLPLVLD 148
>UniRef50_A6XP71 Cluster: Malic enzyme protein 2; n=2;
Mucoromycotina|Rep: Malic enzyme protein 2 - Mortierella
alpina (Mortierella renispora)
Length = 669
Score = 70.1 bits (164), Expect = 4e-11
Identities = 36/104 (34%), Positives = 58/104 (55%), Gaps = 12/104 (11%)
Frame = +2
Query: 236 RQIRKSINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVY----- 400
R I KY++L L + N LFY V D + E +P++YTPTVG ACQ + +Y
Sbjct: 145 RSKSSDIEKYVFLAWLRNTNVRLFYGLVGDQLEETLPLIYTPTVGTACQNYSSIYPFLAP 204
Query: 401 -RRPRGLFITIHDKGHVYDVLKNW------PETDVRAIVVTDGN 511
+P GLF++I+D ++ +++N+ P + V+TDG+
Sbjct: 205 PGQPDGLFLSINDLPNLTQIIQNYKPFPQDPSLTPQIAVITDGS 248
Score = 61.7 bits (143), Expect = 1e-08
Identities = 29/40 (72%), Positives = 31/40 (77%)
Frame = +1
Query: 511 RILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
RILGLGDLG GMGIPVGKL LY A GI P + LPIT+D
Sbjct: 249 RILGLGDLGVGGMGIPVGKLQLYVAGAGIDPRRTLPITLD 288
>UniRef50_Q6AL43 Cluster: Related to NAD-dependent malic enzyme;
n=1; Desulfotalea psychrophila|Rep: Related to
NAD-dependent malic enzyme - Desulfotalea psychrophila
Length = 578
Score = 68.9 bits (161), Expect = 9e-11
Identities = 31/82 (37%), Positives = 48/82 (58%)
Frame = +2
Query: 260 KYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 439
KYI++ L DRN L + + ++ + M I+YTPTVGLA QK+ ++R+ GL +
Sbjct: 81 KYIFIRSLFDRNVTLAHALIQSDLEKFMGIIYTPTVGLAVQKYSAMFRQANGLHFSPDTI 140
Query: 440 GHVYDVLKNWPETDVRAIVVTD 505
D+L+ + D+R VVTD
Sbjct: 141 DQAEDILRRFAHRDIRVAVVTD 162
Score = 50.0 bits (114), Expect = 5e-05
Identities = 23/39 (58%), Positives = 28/39 (71%)
Frame = +1
Query: 514 ILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
ILG+GD GA G+ I +GKL LYT GI P CLPI++D
Sbjct: 166 ILGIGDQGAGGIAICLGKLMLYTQGAGIAPWHCLPISLD 204
>UniRef50_Q95061 Cluster: Malic enzyme; n=2; Giardia
intestinalis|Rep: Malic enzyme - Giardia lamblia
(Giardia intestinalis)
Length = 557
Score = 68.1 bits (159), Expect = 2e-10
Identities = 35/84 (41%), Positives = 49/84 (58%), Gaps = 1/84 (1%)
Frame = +2
Query: 260 KYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYR-RPRGLFITIHD 436
K++YL L + NE LF F + E++PIVYTPTVG AC + L+++ PRG ++
Sbjct: 61 KWLYLTRLQEVNETLFSGFCLKYLKEVLPIVYTPTVGTACSNYSLLWQGYPRGFYLNRTH 120
Query: 437 KGHVYDVLKNWPETDVRAIVVTDG 508
G V + WP + R IV TDG
Sbjct: 121 LGKVKQIFDQWPYSP-RIIVATDG 143
Score = 48.4 bits (110), Expect = 1e-04
Identities = 24/40 (60%), Positives = 26/40 (65%)
Frame = +1
Query: 511 RILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
RILGLGDLG G I VGKL LY+ GG P LPI+ D
Sbjct: 145 RILGLGDLGTGGHQICVGKLTLYSLGGGFAPEHTLPISFD 184
>UniRef50_A4SKB8 Cluster: NAD-dependent malic enzyme; n=2;
Aeromonas|Rep: NAD-dependent malic enzyme - Aeromonas
salmonicida (strain A449)
Length = 516
Score = 64.5 bits (150), Expect = 2e-09
Identities = 31/89 (34%), Positives = 54/89 (60%)
Frame = +2
Query: 242 IRKSINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLF 421
++ ++++ L L + N LFY V ++ E++PI+YTP VG ACQ+ +Y R GL+
Sbjct: 45 MQSPFDQHLLLRQLQEDNPVLFYDLVRHHLPELLPIIYTPVVGEACQRHSDLYLRSHGLY 104
Query: 422 ITIHDKGHVYDVLKNWPETDVRAIVVTDG 508
++ HD+ + D + E +V IV++DG
Sbjct: 105 LSWHDRDDL-DAIFAAVEQEVDVIVISDG 132
Score = 59.7 bits (138), Expect = 6e-08
Identities = 26/41 (63%), Positives = 33/41 (80%)
Frame = +1
Query: 508 KRILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
+R+LGLGDLG GMGI +GKLALY+A GGI P + LP+ +D
Sbjct: 133 ERVLGLGDLGIGGMGICIGKLALYSAAGGINPARTLPLCVD 173
>UniRef50_A2QY66 Cluster: Malic enzyme; n=2; cellular organisms|Rep:
Malic enzyme - Aspergillus niger
Length = 609
Score = 64.1 bits (149), Expect = 3e-09
Identities = 29/84 (34%), Positives = 51/84 (60%), Gaps = 1/84 (1%)
Frame = +2
Query: 260 KYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 439
K ++ + +NE L+Y+ + ++ EM+ I+YTPT G A Q + ++R+P G F+ I D+
Sbjct: 113 KNTFMASMKAQNEVLYYKLIDTHLKEMLSIIYTPTEGDAIQNYSRLFRKPEGCFLNIRDQ 172
Query: 440 GHVYDVLKNWPE-TDVRAIVVTDG 508
+ + L N+ +V IVV+DG
Sbjct: 173 DRIEECLSNFSRGEEVDYIVVSDG 196
Score = 39.1 bits (87), Expect = 0.087
Identities = 19/41 (46%), Positives = 25/41 (60%)
Frame = +1
Query: 508 KRILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
+ ILG+GD G + I V KLAL T GI P + LP+ +D
Sbjct: 197 EEILGIGDQGVGAILISVAKLALTTLCAGIHPSRQLPVVLD 237
Score = 33.9 bits (74), Expect = 3.3
Identities = 15/49 (30%), Positives = 22/49 (44%)
Frame = +3
Query: 129 GHGFYHRRASLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLTSTSIL 275
G F +HGLLPP ++T EEQV+ +N L + +
Sbjct: 69 GSAFTEEERKTFKLHGLLPPNIQTLEEQVQRAYEQYSSRDNDLAKNTFM 117
>UniRef50_Q5CS07 Cluster: Malic enzyme; n=2; Cryptosporidium|Rep:
Malic enzyme - Cryptosporidium parvum Iowa II
Length = 614
Score = 62.5 bits (145), Expect = 8e-09
Identities = 28/40 (70%), Positives = 33/40 (82%)
Frame = +1
Query: 511 RILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
RILGLGDLG GMGIP+GKL+LY LGGI P + LPI++D
Sbjct: 210 RILGLGDLGLNGMGIPMGKLSLYITLGGIDPSKVLPISLD 249
Score = 58.4 bits (135), Expect = 1e-07
Identities = 31/94 (32%), Positives = 51/94 (54%), Gaps = 4/94 (4%)
Frame = +2
Query: 239 QIRKSINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGL--VYRR-- 406
+I +I KY +L + + LF+ + ++ P+VYTPTVG C +F R
Sbjct: 115 KIDSNIGKYTFLENIRSSSFILFHSLLDKYFKDLTPLVYTPTVGEGCIEFSRNPTIRNWL 174
Query: 407 PRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDG 508
GL++ KG +Y++LK++ D+ IV+TDG
Sbjct: 175 GSGLYLNKSHKGRIYEILKDFKSDDIEIIVLTDG 208
Score = 33.5 bits (73), Expect = 4.3
Identities = 13/30 (43%), Positives = 21/30 (70%)
Frame = +1
Query: 88 LSGLDHLKHPGLNKGMAFTIEERHSWAYTG 177
L G++ L++P NKG++FT+EER + G
Sbjct: 64 LKGIELLRNPFYNKGLSFTMEERKEYGLEG 93
>UniRef50_P40375 Cluster: NAD-dependent malic enzyme; n=3;
Schizosaccharomyces pombe|Rep: NAD-dependent malic
enzyme - Schizosaccharomyces pombe (Fission yeast)
Length = 565
Score = 62.5 bits (145), Expect = 8e-09
Identities = 31/87 (35%), Positives = 53/87 (60%), Gaps = 3/87 (3%)
Frame = +2
Query: 254 INKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITI- 430
+ K +YL L N+ LFY ++ ++ EM+PI+YTPT G A ++F +YR P G ++ I
Sbjct: 70 LQKNLYLSQLSVTNQTLFYALISQHLIEMIPIIYTPTEGDAIKQFSDIYRYPEGCYLDID 129
Query: 431 -HDKGHVYDVLKNWPETD-VRAIVVTD 505
+D ++ L + ++D V I++TD
Sbjct: 130 HNDLSYIKQQLSEFGKSDSVEYIIITD 156
Score = 36.7 bits (81), Expect = 0.46
Identities = 18/39 (46%), Positives = 24/39 (61%)
Frame = +1
Query: 514 ILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
ILG+GD G G+ I V K L T G+ P++ LPI +D
Sbjct: 160 ILGIGDQGVGGVLISVAKGHLMTLCAGLDPNRFLPIVLD 198
>UniRef50_A4RZU1 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
enzyme - Ostreococcus lucimarinus CCE9901
Length = 539
Score = 60.5 bits (140), Expect = 3e-08
Identities = 28/54 (51%), Positives = 34/54 (62%)
Frame = +1
Query: 469 AGDGRPCHCCNRRKRILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
A DG +RILGLGDLGA GMGI GK+ LYT G++P CLP+ +D
Sbjct: 120 ADDGVAVAVVTDGERILGLGDLGAGGMGISEGKILLYTVCAGVRPSACLPVCLD 173
Score = 58.8 bits (136), Expect = 1e-07
Identities = 28/71 (39%), Positives = 39/71 (54%)
Frame = +2
Query: 236 RQIRKSINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRG 415
R I + +Y+YL L + FYR + E+MP VYTPTVG AC+K+ + G
Sbjct: 12 RAIADPLERYVYLRELQRASAETFYRALVREPLELMPFVYTPTVGEACEKYHRLGIETNG 71
Query: 416 LFITIHDKGHV 448
++IT D G V
Sbjct: 72 VYITADDAGRV 82
>UniRef50_Q48796 Cluster: Malolactic enzyme; n=49; Bacteria|Rep:
Malolactic enzyme - Oenococcus oeni (Leuconostoc oenos)
Length = 541
Score = 58.8 bits (136), Expect = 1e-07
Identities = 29/101 (28%), Positives = 53/101 (52%), Gaps = 2/101 (1%)
Frame = +2
Query: 251 SINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRG-LFIT 427
++ K ++LM + + N LFY+ + +V E MPIVY PT+ + + ++ P+G F+
Sbjct: 57 NLEKRLFLMEIFNTNHVLFYKLFSQHVVEFMPIVYDPTIADTIENYSELFVEPQGAAFLD 116
Query: 428 IHDKGHVYDVLKNWPE-TDVRAIVVTDGNVFWVLATWAHAG 547
I+ ++ LKN D++ +VV+D + W G
Sbjct: 117 INHPENIQSTLKNAANGRDIKLLVVSDAEGILGIGDWGVQG 157
Score = 43.2 bits (97), Expect = 0.005
Identities = 20/39 (51%), Positives = 24/39 (61%)
Frame = +1
Query: 514 ILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
ILG+GD G G+ I VGKL +YT GI P L + ID
Sbjct: 147 ILGIGDWGVQGVDIAVGKLMVYTVAAGIDPSTVLAVVID 185
>UniRef50_A5C6I9 Cluster: Malic enzyme; n=1; Vitis vinifera|Rep:
Malic enzyme - Vitis vinifera (Grape)
Length = 498
Score = 57.6 bits (133), Expect = 2e-07
Identities = 25/40 (62%), Positives = 30/40 (75%)
Frame = +1
Query: 511 RILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
RILGLGDLG G+GIP+GKL +Y A GI P + LPI +D
Sbjct: 51 RILGLGDLGVQGIGIPIGKLDMYVAAAGINPQRILPIMLD 90
>UniRef50_Q2HCG7 Cluster: Malic enzyme; n=1; Chaetomium
globosum|Rep: Malic enzyme - Chaetomium globosum (Soil
fungus)
Length = 586
Score = 57.6 bits (133), Expect = 2e-07
Identities = 32/102 (31%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = +2
Query: 218 TMQALDRQIRKSINKYIYLMGLLDRNEHLFYRFVADNVA--EMMPIVYTPTVGLACQKFG 391
++Q LD+Q++++ +Y L +N L + V +M +VYTPT G A + F
Sbjct: 65 SIQTLDQQVQRAYEQYSARPDDLAKNTFLTSMKEQNEVLYFKMFSVVYTPTEGDAIENFS 124
Query: 392 LVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGNVF 517
++RRP+G+F+ +HD V+ L W D +V G F
Sbjct: 125 RLFRRPQGVFLNVHDCDRVHHDLSLWGMPDDIDYIVVTGATF 166
Score = 43.6 bits (98), Expect = 0.004
Identities = 20/41 (48%), Positives = 27/41 (65%)
Frame = +1
Query: 508 KRILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
+ ILG+GD G G+ I V KLAL T GI P++ LP+ +D
Sbjct: 184 EEILGIGDQGCGGILISVAKLALMTLCAGIHPNRVLPVVLD 224
>UniRef50_Q7K3R0 Cluster: Malic enzyme; n=2; Sophophora|Rep: Malic
enzyme - Drosophila melanogaster (Fruit fly)
Length = 633
Score = 55.6 bits (128), Expect = 9e-07
Identities = 28/86 (32%), Positives = 44/86 (51%)
Frame = +2
Query: 251 SINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITI 430
++ +YIYL L RN LFY + N +P+ +++ +GL+I I
Sbjct: 125 NVQQYIYLTYLSRRNRRLFYYLLLSNPDRFVPMTDASGSIDLLMVHRMIHSMGQGLYICI 184
Query: 431 HDKGHVYDVLKNWPETDVRAIVVTDG 508
D GHV +L NWP VR ++V++G
Sbjct: 185 KDLGHVSQILSNWPFRCVRCLLVSNG 210
Score = 35.9 bits (79), Expect = 0.81
Identities = 16/41 (39%), Positives = 23/41 (56%)
Frame = +3
Query: 129 GHGFYHRRASLLGIHGLLPPRVKTQEEQVELCKLSIDRYEN 251
G F +L IHGLLP V+T +EQ E+C ++ + N
Sbjct: 84 GLAFTLNERRVLSIHGLLPVAVRTIDEQAEICSNLLESFTN 124
>UniRef50_Q8Y5Y8 Cluster: Lmo1915 protein; n=15; Firmicutes|Rep:
Lmo1915 protein - Listeria monocytogenes
Length = 547
Score = 52.4 bits (120), Expect = 9e-06
Identities = 30/101 (29%), Positives = 51/101 (50%), Gaps = 3/101 (2%)
Frame = +2
Query: 254 INKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRP-RGLFITI 430
++K+ L L + N L+Y V NV + +PI+YTPT+G A ++ Y P LF+
Sbjct: 60 LHKHRLLTNLYNENRTLYYYVVTKNVTDYLPIIYTPTIGDAVIQYHKDYTAPDEALFVDA 119
Query: 431 HDKGHVYDVLKNWPET--DVRAIVVTDGNVFWVLATWAHAG 547
+ +KN+ + ++ IV+TDG + W+ G
Sbjct: 120 FAPEKLSASIKNYAKNNPNIDMIVITDGEGVLGIGDWSVNG 160
Score = 45.2 bits (102), Expect = 0.001
Identities = 19/39 (48%), Positives = 26/39 (66%)
Frame = +1
Query: 514 ILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
+LG+GD G+ I VGKLA+YT G+ P + LP+ ID
Sbjct: 150 VLGIGDWSVNGVKIAVGKLAVYTVAAGLAPDRVLPVVID 188
Score = 33.9 bits (74), Expect = 3.3
Identities = 15/29 (51%), Positives = 20/29 (68%)
Frame = +1
Query: 91 SGLDHLKHPGLNKGMAFTIEERHSWAYTG 177
SG D++ +P LNKG AF+ EER S+ G
Sbjct: 5 SGFDYMNNPLLNKGTAFSKEERASYQLDG 33
>UniRef50_Q5KEY3 Cluster: Malic enzyme; n=1; Filobasidiella
neoformans|Rep: Malic enzyme - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 629
Score = 50.4 bits (115), Expect = 4e-05
Identities = 31/100 (31%), Positives = 53/100 (53%), Gaps = 16/100 (16%)
Frame = +2
Query: 254 INKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIH 433
I K+ +L L D+N+ LFYR + D + E++ ++YTP A + ++RRP G +I+
Sbjct: 106 ILKHAFLASLRDQNQVLFYRLMQDRLKELLGVLYTPGAAEAVAGYSSLFRRPVGCYISFP 165
Query: 434 D--------KGHVYDVLK--------NWPETDVRAIVVTD 505
+ +GH+ DV + N P+ + +VVTD
Sbjct: 166 NQDGMRAQLEGHLTDVNRTADVAYDSNKPDDAIDLVVVTD 205
Score = 42.7 bits (96), Expect = 0.007
Identities = 19/39 (48%), Positives = 25/39 (64%)
Frame = +1
Query: 514 ILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
ILG+GD G G+ I K ALYT GI P++ LP+ +D
Sbjct: 209 ILGIGDQGVGGITISTSKAALYTLGAGINPNRILPVVLD 247
>UniRef50_Q5KBK5 Cluster: Nad-dependent malic enzyme, putative; n=2;
Filobasidiella neoformans|Rep: Nad-dependent malic
enzyme, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 584
Score = 50.4 bits (115), Expect = 4e-05
Identities = 30/87 (34%), Positives = 46/87 (52%), Gaps = 1/87 (1%)
Frame = +2
Query: 251 SINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFIT- 427
+I K +L + +N LFY + ++ EM PIVYTPT A + ++RR GL++T
Sbjct: 81 NILKNSFLQSMKAQNWTLFYALLQAHLVEMFPIVYTPTEADAIADYSHLFRRSEGLYLTP 140
Query: 428 IHDKGHVYDVLKNWPETDVRAIVVTDG 508
+K D L ++ IVV+DG
Sbjct: 141 PGEKNMEEDFLDACEGRELELIVVSDG 167
Score = 44.8 bits (101), Expect = 0.002
Identities = 18/39 (46%), Positives = 27/39 (69%)
Frame = +1
Query: 514 ILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
ILG+GD G+ G+GI K +Y+ + G+ P +CL IT+D
Sbjct: 170 ILGIGDQGSGGIGISGAKAVIYSLIAGVDPAKCLAITLD 208
>UniRef50_P36013 Cluster: NAD-dependent malic enzyme, mitochondrial
precursor; n=15; Saccharomycetales|Rep: NAD-dependent
malic enzyme, mitochondrial precursor - Saccharomyces
cerevisiae (Baker's yeast)
Length = 669
Score = 48.8 bits (111), Expect = 1e-04
Identities = 25/89 (28%), Positives = 50/89 (56%), Gaps = 1/89 (1%)
Frame = +2
Query: 242 IRKSINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLF 421
++ + K ++ L +N+ L++ + ++ E++PI+YTPT G A + +R+P G+F
Sbjct: 150 LKTPLAKNDFMTSLRVQNKVLYFALIRRHIKELVPIIYTPTEGDAIAAYSHRFRKPEGVF 209
Query: 422 ITIHDKGHVYDVLKNW-PETDVRAIVVTD 505
+ I + + L + + DV IVV+D
Sbjct: 210 LDITEPDSIECRLATYGGDKDVDYIVVSD 238
Score = 44.0 bits (99), Expect = 0.003
Identities = 20/39 (51%), Positives = 26/39 (66%)
Frame = +1
Query: 514 ILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 630
ILG+GD G G+ I + KLAL T GGI P + LP+ +D
Sbjct: 242 ILGIGDQGIGGVRIAISKLALMTLCGGIHPGRVLPVCLD 280
>UniRef50_Q9S4T5 Cluster: NAD-malate oxidoreductase homolog; n=15;
Legionellales|Rep: NAD-malate oxidoreductase homolog -
Legionella pneumophila
Length = 117
Score = 47.2 bits (107), Expect = 3e-04
Identities = 18/41 (43%), Positives = 31/41 (75%)
Frame = +2
Query: 254 INKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLA 376
+ ++IYL L D+N+ +FY+ ++ ++ EM+PI+YTP VG A
Sbjct: 77 LQQHIYLNNLHDKNQIVFYKLLSRHLGEMLPIIYTPIVGAA 117
>UniRef50_UPI0000DB7FF6 Cluster: PREDICTED: hypothetical protein,
partial; n=1; Apis mellifera|Rep: PREDICTED:
hypothetical protein, partial - Apis mellifera
Length = 95
Score = 43.2 bits (97), Expect = 0.005
Identities = 19/37 (51%), Positives = 26/37 (70%)
Frame = +1
Query: 19 TYSEMERDRIGLXGSGDGQPTSGLSGLDHLKHPGLNK 129
T S ++RD++G G GD ++ L GLDHLK+P LNK
Sbjct: 59 TMSSVQRDQLGQRGHGDAMCSNLLRGLDHLKNPRLNK 95
>UniRef50_Q8S484 Cluster: Putative NADP-dependent malic enzyme; n=1;
Zea mays|Rep: Putative NADP-dependent malic enzyme - Zea
mays (Maize)
Length = 309
Score = 40.7 bits (91), Expect = 0.028
Identities = 26/71 (36%), Positives = 34/71 (47%)
Frame = +2
Query: 293 NEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWP 472
+E LFY+ + DNV E++P VYT T G V DVLKNWP
Sbjct: 225 DERLFYKLLIDNVVELLPFVYTTT-------------------------GKVLDVLKNWP 259
Query: 473 ETDVRAIVVTD 505
+++ I VTD
Sbjct: 260 HRNIQVIFVTD 270
>UniRef50_A3XN08 Cluster: Putative uncharacterized protein; n=1;
Leeuwenhoekiella blandensis MED217|Rep: Putative
uncharacterized protein - Leeuwenhoekiella blandensis
MED217
Length = 390
Score = 34.3 bits (75), Expect = 2.5
Identities = 13/32 (40%), Positives = 19/32 (59%)
Frame = +2
Query: 434 DKGHVYDVLKNWPETDVRAIVVTDGNVFWVLA 529
D H D KNWP+ D +++TDGN + +A
Sbjct: 352 DVKHSSDYHKNWPDYDSEGLLITDGNYYRAMA 383
>UniRef50_Q08PM3 Cluster: Hemin ABC transporter, periplasmic
hemin-binding protein; n=1; Stigmatella aurantiaca
DW4/3-1|Rep: Hemin ABC transporter, periplasmic
hemin-binding protein - Stigmatella aurantiaca DW4/3-1
Length = 332
Score = 33.9 bits (74), Expect = 3.3
Identities = 34/122 (27%), Positives = 53/122 (43%), Gaps = 1/122 (0%)
Frame = +2
Query: 146 SKSVTLGHTRVVTTTS-QDARGAG*TMQALDRQIRKSINKYIYLMGLLDRNEHLFYRFVA 322
S + +G +T+TS + RGA + L+ ++ I+ GLL R E L F A
Sbjct: 129 SPDLVIGAEENLTSTSAEQLRGAKLPVLILENSSKEGIS------GLLRRIEVLARVFNA 182
Query: 323 DNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVT 502
+ + M T V +K L ++PR LF+ H G + K ET A++
Sbjct: 183 EEAGQRMKQDITRQVAELEKKIALAKKKPRVLFLYAHSPGEAFVYGK---ETGTHALIEL 239
Query: 503 DG 508
G
Sbjct: 240 AG 241
>UniRef50_A1CKF3 Cluster: Stress response protein (Ish1), putative;
n=5; Pezizomycotina|Rep: Stress response protein (Ish1),
putative - Aspergillus clavatus
Length = 516
Score = 33.9 bits (74), Expect = 3.3
Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 1/53 (1%)
Frame = -2
Query: 418 EAPW-SAVHKPELLTGQANRRSVHNWHHFSHVIRDETVEQMLIAVQEPHKIDV 263
+A W S V KP GQA + HNWHH I D + L A + H + V
Sbjct: 63 KANWDSKVQKP---LGQAAEHTTHNWHHAKEWIFDTWSDSQLKAFLDRHGVPV 112
>UniRef50_Q1WD27 Cluster: ScfA; n=2; Emericella nidulans|Rep: ScfA -
Emericella nidulans (Aspergillus nidulans)
Length = 729
Score = 33.5 bits (73), Expect = 4.3
Identities = 37/140 (26%), Positives = 58/140 (41%), Gaps = 7/140 (5%)
Frame = -3
Query: 618 GQTLMRLDASERGVEREFA--HWDAHPACAQVAKTQNTFPSVT-TMARTSVSGQFLRTSY 448
G LD + GV F +W+ HPA A A +N S T+ + Q L+ +Y
Sbjct: 404 GNAQASLDTWKSGVSPVFKQQYWEEHPALASTAIEKNPPSSENRTIRHLFLQSQMLQLTY 463
Query: 447 TCPLSWIVMKRPLGRRYTSPNF*QARPTVGVYTIGI---ISATLSATKR*NRCS-LRSKS 280
+ +I RPL P F R V + + + +L A R +R S + +S
Sbjct: 464 DSAVLFI--NRPLLEHQAKPEF---RTAVAEHLSAVRLSMDLSLKAALRVSRVSPVHHES 518
Query: 279 PIR*MYLLMDFRICRSRACI 220
++LM+F I C+
Sbjct: 519 EFSLSFVLMNFFIAGVILCL 538
>UniRef50_Q7NAH7 Cluster: Cysteinyl-tRNA synthetase; n=1; Mycoplasma
gallisepticum|Rep: Cysteinyl-tRNA synthetase -
Mycoplasma gallisepticum
Length = 462
Score = 33.1 bits (72), Expect = 5.7
Identities = 15/51 (29%), Positives = 29/51 (56%)
Frame = +2
Query: 233 DRQIRKSINKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQK 385
+ ++ KS+N +IY+ L++ + + R+V N A P+ + T+ A QK
Sbjct: 285 NEKMSKSLNNFIYVKHLIESHNYRAIRWVFYNTAHTQPLNFDGTIIKAAQK 335
>UniRef50_Q1EI20 Cluster: Putative uncharacterized protein; n=2;
root|Rep: Putative uncharacterized protein - uncultured
organism
Length = 302
Score = 32.7 bits (71), Expect = 7.5
Identities = 10/20 (50%), Positives = 16/20 (80%)
Frame = +2
Query: 413 GLFITIHDKGHVYDVLKNWP 472
G+++TI + G + D+LKNWP
Sbjct: 210 GVYLTIREPGQITDILKNWP 229
>UniRef50_A0WC26 Cluster: Multi-sensor hybrid histidine kinase
precursor; n=2; Geobacter lovleyi SZ|Rep: Multi-sensor
hybrid histidine kinase precursor - Geobacter lovleyi SZ
Length = 1007
Score = 32.7 bits (71), Expect = 7.5
Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Frame = +2
Query: 368 GLACQKFGLVYRRPRGL-FITIHDKGHVYDVLKNWPETDVRAIVVTDG 508
G+ K +YR R FI HD+ H+++ +KN PE + IV DG
Sbjct: 198 GIFDSKGVFLYRTARANEFIGKHDQPHLFEQMKNGPEEGIIDIVSNDG 245
>UniRef50_Q10PB7 Cluster: Expressed protein; n=1; Oryza sativa
(japonica cultivar-group)|Rep: Expressed protein - Oryza
sativa subsp. japonica (Rice)
Length = 242
Score = 32.7 bits (71), Expect = 7.5
Identities = 19/44 (43%), Positives = 25/44 (56%), Gaps = 5/44 (11%)
Frame = -1
Query: 554 MPIPH-APKSPRP---RIRFRRLQQ-WHGRPSPASS*EHRIHVP 438
+P+PH +P S P RIR RR ++ W RP P S HR+ P
Sbjct: 103 LPLPHISPSSLHPSLARIRRRRRREGWFRRPLPLSHGSHRLFAP 146
>UniRef50_UPI00005A0FA5 Cluster: PREDICTED: hypothetical protein
XP_851328; n=1; Canis lupus familiaris|Rep: PREDICTED:
hypothetical protein XP_851328 - Canis familiaris
Length = 154
Score = 32.3 bits (70), Expect = 10.0
Identities = 26/77 (33%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Frame = -1
Query: 479 PSPASS*EHRIHVPYRGS**RGPLVGGTQARTSDRPG-QPSECTQLASFQPRYPRRNGRT 303
P PA R P RG RGP VG T++++ G P T + P+ R+G
Sbjct: 83 PPPAPPSSSRTERPGRGQRVRGPSVGLTESKSRGHQGPSPPPRTHSPALPPQEEPRDGE- 141
Query: 302 DAHCGPRAP*DRCTC*W 252
GPR P D C W
Sbjct: 142 ----GPR-PTDCIPCSW 153
>UniRef50_Q4SBA5 Cluster: Chromosome undetermined SCAF14676, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF14676, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 224
Score = 32.3 bits (70), Expect = 10.0
Identities = 17/44 (38%), Positives = 23/44 (52%)
Frame = +3
Query: 366 LAWPVRSSGLCTADQGASSSRSTIRDMYTMFLRTGRRRTSVPLL 497
L WP+ G + QG SS R+T+ D L G R S+PL+
Sbjct: 16 LLWPLHRRGNPSLKQGFSSQRATLVDSLLEELHQGPRPFSLPLM 59
>UniRef50_Q1MKF6 Cluster: Putative uncharacterized protein; n=1;
Rhizobium leguminosarum bv. viciae 3841|Rep: Putative
uncharacterized protein - Rhizobium leguminosarum bv.
viciae (strain 3841)
Length = 337
Score = 32.3 bits (70), Expect = 10.0
Identities = 17/55 (30%), Positives = 23/55 (41%)
Frame = +3
Query: 174 GLLPPRVKTQEEQVELCKLSIDRYENPLTSTSILWGSWTAMSICSTVSSRITWLK 338
GL+PPR+ Q Q + K+ I +N + I WG S V W K
Sbjct: 243 GLIPPRLNKQYNQHPISKIIIQSVQNRMPDELIFWGIGLTDSDVDLVELYKAWSK 297
>UniRef50_Q17IF3 Cluster: Putative uncharacterized protein; n=1;
Aedes aegypti|Rep: Putative uncharacterized protein -
Aedes aegypti (Yellowfever mosquito)
Length = 2052
Score = 32.3 bits (70), Expect = 10.0
Identities = 16/64 (25%), Positives = 31/64 (48%)
Frame = +3
Query: 375 PVRSSGLCTADQGASSSRSTIRDMYTMFLRTGRRRTSVPLL*PTETYSGSWRLGRMRDGH 554
PV+S+ C + + S + ++M++MF+ G P P +S + +G ++
Sbjct: 581 PVKSASSCNSSRAESVEKDAKKNMFSMFIDIGNEAAPKPSSAP-RRFSAASTVGPTKEES 639
Query: 555 PSGQ 566
P GQ
Sbjct: 640 PIGQ 643
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 715,301,640
Number of Sequences: 1657284
Number of extensions: 16388504
Number of successful extensions: 55785
Number of sequences better than 10.0: 73
Number of HSP's better than 10.0 without gapping: 52449
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 55733
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 46881492319
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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