Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= NV021141
(733 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_A7SQS1 Cluster: Predicted protein; n=1; Nematostella ve... 129 8e-29
UniRef50_P08249 Cluster: Malate dehydrogenase, mitochondrial pre... 129 8e-29
UniRef50_P40926 Cluster: Malate dehydrogenase, mitochondrial pre... 128 1e-28
UniRef50_Q9SN86 Cluster: Malate dehydrogenase, chloroplast precu... 125 1e-27
UniRef50_Q42972 Cluster: Malate dehydrogenase, glyoxysomal precu... 121 2e-26
UniRef50_A2QMH9 Cluster: Malate dehydrogenase; n=7; Fungi/Metazo... 118 2e-25
UniRef50_Q6BM17 Cluster: Malate dehydrogenase; n=4; Eukaryota|Re... 111 1e-23
UniRef50_Q9Y7R8 Cluster: Malate dehydrogenase; n=13; Dikarya|Rep... 109 7e-23
UniRef50_Q6FL22 Cluster: Malate dehydrogenase; n=1; Candida glab... 101 2e-20
UniRef50_P22133 Cluster: Malate dehydrogenase, cytoplasmic; n=3;... 100 3e-20
UniRef50_Q9VU29 Cluster: Malate dehydrogenase; n=5; Protostomia|... 98 2e-19
UniRef50_A3BMG8 Cluster: Putative uncharacterized protein; n=3; ... 95 1e-18
UniRef50_Q4Q3J3 Cluster: Malate dehydrogenase, putative; n=3; Le... 95 2e-18
UniRef50_Q75AT4 Cluster: ADL164Cp; n=2; Saccharomycetales|Rep: A... 95 2e-18
UniRef50_P32419 Cluster: Malate dehydrogenase, peroxisomal; n=24... 94 3e-18
UniRef50_Q4QDF0 Cluster: Glycosomal malate dehydrogenase; n=9; T... 93 5e-18
UniRef50_A7TSF5 Cluster: Putative uncharacterized protein; n=1; ... 89 1e-16
UniRef50_Q9VU28 Cluster: Malate dehydrogenase; n=3; Sophophora|R... 87 3e-16
UniRef50_A7TL95 Cluster: Putative uncharacterized protein; n=1; ... 86 1e-15
UniRef50_Q6CP51 Cluster: Similar to sp|P22133 Saccharomyces cere... 85 2e-15
UniRef50_UPI00005A0834 Cluster: PREDICTED: similar to Malate deh... 83 7e-15
UniRef50_Q5ENS5 Cluster: Malate dehydrogenase; n=1; Heterocapsa ... 79 8e-14
UniRef50_Q86DP2 Cluster: Malate dehydrogenase; n=11; Fungi/Metaz... 78 3e-13
UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3; Acti... 74 4e-12
UniRef50_Q64P62 Cluster: Malate dehydrogenase; n=28; Bacteroidet... 71 3e-11
UniRef50_Q8TWG5 Cluster: Malate dehydrogenase; n=2; Euryarchaeot... 71 4e-11
UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Re... 70 5e-11
UniRef50_A6Q7S2 Cluster: Malate dehydrogenase, NAD-dependent; n=... 70 7e-11
UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2... 70 7e-11
UniRef50_A7I2F1 Cluster: Malate dehydrogenase; n=1; Campylobacte... 69 2e-10
UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|R... 69 2e-10
UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular o... 67 5e-10
UniRef50_A7GYI6 Cluster: Lactate/malate dehydrogenase, NAD bindi... 66 8e-10
UniRef50_Q3J7E7 Cluster: Malate dehydrogenase; n=5; Gammaproteob... 66 8e-10
UniRef50_O08349 Cluster: Malate dehydrogenase; n=1; Archaeoglobu... 66 8e-10
UniRef50_Q6VVP7 Cluster: Malate dehydrogenase; n=6; Plasmodium|R... 66 1e-09
UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter... 65 1e-09
UniRef50_P16115 Cluster: L-lactate dehydrogenase; n=4; Thermotog... 64 3e-09
UniRef50_Q8ZVB2 Cluster: Malate dehydrogenase; n=14; Thermoprote... 64 3e-09
UniRef50_Q017A6 Cluster: Malate dehydrogenase; n=2; cellular org... 64 4e-09
UniRef50_Q18WQ6 Cluster: Malate dehydrogenase, NAD-dependent; n=... 62 1e-08
UniRef50_A4L2P0 Cluster: L-lactate dehydrogenase; n=4; Lactobaci... 62 1e-08
UniRef50_A0RPE9 Cluster: Malate dehydrogenase; n=1; Campylobacte... 62 1e-08
UniRef50_Q979N9 Cluster: Malate dehydrogenase; n=4; Thermoplasma... 61 2e-08
UniRef50_UPI0000D571DB Cluster: PREDICTED: similar to CG7998-PA;... 60 4e-08
UniRef50_P11386 Cluster: Malate dehydrogenase; n=6; Sulfolobacea... 60 4e-08
UniRef50_A2SSY4 Cluster: L-lactate dehydrogenase; n=3; Methanomi... 60 7e-08
UniRef50_A0RXX8 Cluster: Malate/L-lactate dehydrogenase; n=1; Ce... 59 1e-07
UniRef50_O26290 Cluster: Malate dehydrogenase; n=2; Methanobacte... 59 1e-07
UniRef50_Q4Q3J5 Cluster: Malate dehydrogenase, putative; n=5; Tr... 58 2e-07
UniRef50_Q7NHJ3 Cluster: Malate dehydrogenase; n=13; cellular or... 58 2e-07
UniRef50_Q3ZZJ7 Cluster: Malate dehydrogenase; n=5; cellular org... 58 2e-07
UniRef50_Q6A9C3 Cluster: L-lactate dehydrogenase; n=2; Propionib... 58 2e-07
UniRef50_A3EWH3 Cluster: Malate/lactate dehydrogenase; n=1; Lept... 58 2e-07
UniRef50_Q892U0 Cluster: L-lactate dehydrogenase; n=12; Bacteria... 58 3e-07
UniRef50_UPI00015BB1FC Cluster: malate dehydrogenase (NAD); n=1;... 57 4e-07
UniRef50_Q8XP62 Cluster: L-lactate dehydrogenase; n=11; Clostrid... 57 4e-07
UniRef50_A4BB89 Cluster: Lactate dehydrogenase; n=2; Gammaproteo... 57 5e-07
UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=... 57 5e-07
UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex ae... 57 5e-07
UniRef50_A7DRG3 Cluster: Lactate/malate dehydrogenase; n=1; Cand... 56 7e-07
UniRef50_Q7M9A7 Cluster: Malate dehydrogenase; n=4; Epsilonprote... 56 7e-07
UniRef50_P62056 Cluster: L-lactate dehydrogenase; n=2; Bacteria|... 56 9e-07
UniRef50_A5Z9B1 Cluster: Putative uncharacterized protein; n=1; ... 56 1e-06
UniRef50_P0C0J4 Cluster: L-lactate dehydrogenase; n=5; Mycoplasm... 56 1e-06
UniRef50_Q81K80 Cluster: L-lactate dehydrogenase 2; n=12; Firmic... 56 1e-06
UniRef50_A2SNY0 Cluster: Malate/lactate dehydrogenases-like prot... 54 3e-06
UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;... 54 3e-06
UniRef50_UPI0000D55CD8 Cluster: PREDICTED: similar to Malate DeH... 54 4e-06
UniRef50_A5KJY5 Cluster: Putative uncharacterized protein; n=2; ... 54 4e-06
UniRef50_Q1FID3 Cluster: L-lactate dehydrogenase precursor; n=1;... 54 5e-06
UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2; ... 54 5e-06
UniRef50_P50933 Cluster: L-lactate dehydrogenase; n=7; Bacteria|... 54 5e-06
UniRef50_P59390 Cluster: L-lactate dehydrogenase 2; n=8; Lactoba... 54 5e-06
UniRef50_Q6KIP9 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm... 53 8e-06
UniRef50_P19869 Cluster: L-lactate dehydrogenase 2; n=17; Bacter... 53 8e-06
UniRef50_Q2S4R2 Cluster: L-lactate dehydrogenase; n=1; Salinibac... 52 1e-05
UniRef50_UPI0000DB76D8 Cluster: PREDICTED: similar to CG7998-PA;... 52 1e-05
UniRef50_UPI000038D9FF Cluster: COG0039: Malate/lactate dehydrog... 52 2e-05
UniRef50_O51114 Cluster: L-lactate dehydrogenase; n=4; Borrelia ... 52 2e-05
UniRef50_Q838C9 Cluster: L-lactate dehydrogenase 2; n=9; Bacilli... 52 2e-05
UniRef50_A3DCA4 Cluster: L-lactate dehydrogenase precursor; n=2;... 51 3e-05
UniRef50_P0A3M9 Cluster: L-lactate dehydrogenase; n=140; Bacteri... 51 3e-05
UniRef50_Q27743 Cluster: L-lactate dehydrogenase; n=17; Apicompl... 51 3e-05
UniRef50_Q98PG4 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm... 51 3e-05
UniRef50_Q07841 Cluster: Malate dehydrogenase; n=7; Halobacteria... 50 4e-05
UniRef50_A3JXA9 Cluster: L-lactate dehydrogenase; n=1; Sagittula... 50 8e-05
UniRef50_A1HSK3 Cluster: Lactate/malate dehydrogenase; n=1; Ther... 50 8e-05
UniRef50_P62051 Cluster: L-lactate dehydrogenase; n=2; Desulfovi... 49 1e-04
UniRef50_Q6JH30 Cluster: Lactate dehydrogenase; n=3; Plasmodium ... 48 2e-04
UniRef50_Q03BE6 Cluster: L-lactate dehydrogenase; n=1; Lactobaci... 48 2e-04
UniRef50_P61973 Cluster: Malate dehydrogenase; n=43; Bacteria|Re... 48 2e-04
UniRef50_Q87JV1 Cluster: Lactate dehydrogenase; n=4; Vibrio|Rep:... 47 4e-04
UniRef50_UPI00015B4591 Cluster: PREDICTED: similar to mitochondr... 47 5e-04
UniRef50_Q7UY63 Cluster: L-lactate/malate dehydrogenase; n=2; Pl... 47 5e-04
UniRef50_Q7MTK2 Cluster: Malate dehydrogenase; n=4; Bacteroidale... 47 5e-04
UniRef50_Q6F0L9 Cluster: L-lactate dehydrogenase; n=6; Mollicute... 47 5e-04
UniRef50_A0D8T3 Cluster: Malate dehydrogenase; n=2; Paramecium t... 46 0.001
UniRef50_A6M0Q2 Cluster: L-lactate dehydrogenase; n=1; Clostridi... 46 0.001
UniRef50_Q8I8U4 Cluster: Lactate dehydrogenase; n=3; Eimeriorina... 46 0.001
UniRef50_A1U9V0 Cluster: Lactate/malate dehydrogenase; n=6; Acti... 45 0.002
UniRef50_Q9PHY2 Cluster: Probable malate dehydrogenase; n=12; Ca... 45 0.002
UniRef50_Q4UJ29 Cluster: L-lactate dehydrogenase, putative; n=2;... 45 0.002
UniRef50_UPI0000DB6C4F Cluster: PREDICTED: similar to Malate DeH... 44 0.003
UniRef50_UPI0000D56DC5 Cluster: PREDICTED: similar to Malate deh... 44 0.004
UniRef50_A2UB98 Cluster: Lactate/malate dehydrogenase precursor;... 44 0.005
UniRef50_Q9GPV2 Cluster: Cytosolic malate dehydrogenase; n=4; Tr... 44 0.005
UniRef50_Q23CW4 Cluster: Malate dehydrogenase, cytoplasmic, puta... 43 0.007
UniRef50_Q9EVR0 Cluster: L-lactate dehydrogenase; n=1; Selenomon... 43 0.007
UniRef50_Q8ELF0 Cluster: L-lactate dehydrogenase; n=5; Bacillace... 43 0.007
UniRef50_Q1IRL5 Cluster: L-lactate dehydrogenase; n=6; Bacteria|... 43 0.009
UniRef50_P20619 Cluster: L-lactate dehydrogenase X; n=14; Bacill... 43 0.009
UniRef50_Q64YY6 Cluster: Malate dehydrogenase; n=5; Bacteroidale... 42 0.012
UniRef50_A1W9K7 Cluster: Malate dehydrogenase; n=95; cellular or... 42 0.012
UniRef50_Q81XJ7 Cluster: L-lactate dehydrogenase 3; n=13; Firmic... 42 0.016
UniRef50_A4A2L6 Cluster: L-lactate dehydrogenase; n=4; Bacteria|... 42 0.021
UniRef50_A2Q223 Cluster: Lactate/malate dehydrogenase, alpha/bet... 41 0.036
UniRef50_A2E124 Cluster: Malate dehydrogenase; n=6; Trichomonadi... 41 0.036
UniRef50_A3CTN0 Cluster: Lactate/malate dehydrogenase; n=1; Meth... 40 0.048
UniRef50_Q0PQR8 Cluster: Malate dehydrogenase NAD-dependent; n=1... 40 0.063
UniRef50_Q9Z6N1 Cluster: Malate dehydrogenase; n=8; Chlamydiacea... 40 0.083
UniRef50_Q9P4B6 Cluster: L-lactate dehydrogenase A; n=48; Rhizop... 40 0.083
UniRef50_Q7QQW5 Cluster: Malate dehydrogenase; n=2; Giardia inte... 39 0.15
UniRef50_A2QJT7 Cluster: Catalytic activity: precursor; n=1; Asp... 39 0.15
UniRef50_Q4JY42 Cluster: L-lactate dehydrogenase; n=1; Corynebac... 39 0.15
UniRef50_UPI00015B5ACF Cluster: PREDICTED: similar to ENSANGP000... 38 0.19
UniRef50_P47698 Cluster: L-lactate dehydrogenase; n=2; Mycoplasm... 38 0.19
UniRef50_Q0BVX0 Cluster: 1-acyl-sn-glycerol-3-phosphate acyltran... 38 0.25
UniRef50_A7SAG3 Cluster: Predicted protein; n=1; Nematostella ve... 37 0.44
UniRef50_Q0UX88 Cluster: L-lactate dehydrogenase; n=2; Phaeospha... 37 0.44
UniRef50_A2SR33 Cluster: Lactate/malate dehydrogenase; n=1; Meth... 37 0.44
UniRef50_Q97DC6 Cluster: L-lactate dehydrogenase 2; n=1; Clostri... 37 0.44
UniRef50_Q017A7 Cluster: Chromosome 06 contig 1, DNA sequence; n... 36 0.77
UniRef50_P59050 Cluster: L-lactate dehydrogenase 1; n=3; Bifidob... 36 1.0
UniRef50_UPI0000DB7268 Cluster: PREDICTED: similar to L-lactate ... 36 1.4
UniRef50_A5IYS9 Cluster: L-lactate dehydrogenase; n=2; Mycoplasm... 35 1.8
UniRef50_Q5B0T8 Cluster: Putative uncharacterized protein; n=1; ... 35 1.8
UniRef50_A5FD47 Cluster: RagB/SusD domain protein precursor; n=1... 35 2.4
UniRef50_Q4DTK0 Cluster: Putative uncharacterized protein; n=1; ... 35 2.4
UniRef50_UPI00015537B7 Cluster: PREDICTED: hypothetical protein;... 34 3.1
UniRef50_UPI000023E362 Cluster: hypothetical protein FG01393.1; ... 34 3.1
UniRef50_O52354 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm... 34 3.1
UniRef50_O26630 Cluster: UDP-N-acetylmuramyl tripeptide syntheta... 34 4.1
UniRef50_Q3MGZ6 Cluster: Putative uncharacterized protein precur... 33 5.5
UniRef50_Q7UX97 Cluster: Arylsulfatase B [Precursor]; n=1; Pirel... 33 7.2
UniRef50_A2SGX5 Cluster: Putative uncharacterized protein; n=1; ... 33 7.2
UniRef50_Q8IE66 Cluster: Oxidoreductase, putative; n=6; Plasmodi... 33 7.2
UniRef50_Q5QU95 Cluster: Uncharacterized conserved secreted prot... 33 9.5
UniRef50_A6S058 Cluster: Mitochondrial ribosome small subunit co... 33 9.5
UniRef50_P15719 Cluster: Malate dehydrogenase [NADP], chloroplas... 33 9.5
UniRef50_Q8NHM5 Cluster: JmjC domain-containing histone demethyl... 33 9.5
>UniRef50_A7SQS1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 254
Score = 129 bits (311), Expect = 8e-29
Identities = 64/118 (54%), Positives = 86/118 (72%), Gaps = 1/118 (0%)
Frame = +3
Query: 252 SDLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIA 431
+DLSH++T AKV+ H+GP++L AA++ VV IPAGVPRKPGMTRDDLFNTNASIV++++
Sbjct: 10 ADLSHISTRAKVTSHQGPDDLKAALEGCSVVAIPAGVPRKPGMTRDDLFNTNASIVKNLS 69
Query: 432 LSIAQNAPKAIVAIITNPVNSTVPIALKCSRRREC-TTRTACSASPLWTYRAATFVGE 602
+ A++ PKAI+ II+NPVNSTVPIA + ++ + L RA TFV E
Sbjct: 70 EACAKHCPKAIICIISNPVNSTVPIASEVYKKAGVYDPARILGVTTLDIVRAHTFVAE 127
>UniRef50_P08249 Cluster: Malate dehydrogenase, mitochondrial
precursor; n=514; cellular organisms|Rep: Malate
dehydrogenase, mitochondrial precursor - Mus musculus
(Mouse)
Length = 338
Score = 129 bits (311), Expect = 8e-29
Identities = 65/127 (51%), Positives = 83/127 (65%), Gaps = 1/127 (0%)
Frame = +3
Query: 240 PRRRSDLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIV 419
P +DLSH+ T A V G+ GPE+L +K DVVVIPAGVPRKPGMTRDDLFNTNA+IV
Sbjct: 62 PGVAADLSHIETRANVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIV 121
Query: 420 RDIALSIAQNAPKAIVAIITNPVNSTVPIALKCSRRREC-TTRTACSASPLWTYRAATFV 596
+ + AQ+ P+A+V II NPVNST+PI + ++ + L RA TFV
Sbjct: 122 ATLTAACAQHCPEAMVCIIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFV 181
Query: 597 GEINGVD 617
E+ G+D
Sbjct: 182 AELKGLD 188
Score = 71.3 bits (167), Expect = 2e-11
Identities = 34/63 (53%), Positives = 45/63 (71%), Gaps = 1/63 (1%)
Frame = +2
Query: 509 SEVLKKAGVYDPNRVLGVTTLDVSRCHLRRRD-QWRGPNSVAVPVIGGHSGITIIPILSQ 685
+EV KK GVY+PN++ GVTTLD+ R + + + P V VPVIGGH+G TIIP++SQ
Sbjct: 152 AEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQ 211
Query: 686 CQP 694
C P
Sbjct: 212 CTP 214
Score = 62.9 bits (146), Expect = 8e-09
Identities = 36/70 (51%), Positives = 46/70 (65%)
Frame = +1
Query: 46 MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYD 225
M S +PA A++ ++FST++Q N K IGQPL+LLLK +PLV+RL LYD
Sbjct: 1 MLSALARPAGAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYD 57
Query: 226 IAPVTPGVAA 255
IA TPGVAA
Sbjct: 58 IAH-TPGVAA 66
>UniRef50_P40926 Cluster: Malate dehydrogenase, mitochondrial
precursor; n=119; cellular organisms|Rep: Malate
dehydrogenase, mitochondrial precursor - Homo sapiens
(Human)
Length = 338
Score = 128 bits (309), Expect = 1e-28
Identities = 63/127 (49%), Positives = 83/127 (65%), Gaps = 1/127 (0%)
Frame = +3
Query: 240 PRRRSDLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIV 419
P +DLSH+ T A V G+ GPE+L +K DVVVIPAGVPRKPGMTRDDLFNTNA+IV
Sbjct: 62 PGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIV 121
Query: 420 RDIALSIAQNAPKAIVAIITNPVNSTVPIALKCSRRREC-TTRTACSASPLWTYRAATFV 596
+ + AQ+ P+A++ +I NPVNST+PI + ++ + L RA TFV
Sbjct: 122 ATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFV 181
Query: 597 GEINGVD 617
E+ G+D
Sbjct: 182 AELKGLD 188
Score = 71.3 bits (167), Expect = 2e-11
Identities = 34/63 (53%), Positives = 45/63 (71%), Gaps = 1/63 (1%)
Frame = +2
Query: 509 SEVLKKAGVYDPNRVLGVTTLDVSRCHLRRRD-QWRGPNSVAVPVIGGHSGITIIPILSQ 685
+EV KK GVY+PN++ GVTTLD+ R + + + P V VPVIGGH+G TIIP++SQ
Sbjct: 152 AEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQ 211
Query: 686 CQP 694
C P
Sbjct: 212 CTP 214
Score = 61.7 bits (143), Expect = 2e-08
Identities = 35/70 (50%), Positives = 46/70 (65%)
Frame = +1
Query: 46 MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYD 225
M S +P + A++ ++FST++Q N K IGQPL+LLLK +PLV+RL LYD
Sbjct: 1 MLSALARPVSAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYD 57
Query: 226 IAPVTPGVAA 255
IA TPGVAA
Sbjct: 58 IAH-TPGVAA 66
>UniRef50_Q9SN86 Cluster: Malate dehydrogenase, chloroplast
precursor; n=41; cellular organisms|Rep: Malate
dehydrogenase, chloroplast precursor - Arabidopsis
thaliana (Mouse-ear cress)
Length = 403
Score = 125 bits (301), Expect = 1e-27
Identities = 61/118 (51%), Positives = 82/118 (69%), Gaps = 1/118 (0%)
Frame = +3
Query: 252 SDLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIA 431
+DLSH NTP++V GP EL+ +KD +VVVIPAGVPRKPGMTRDDLFN NA+IV+ +
Sbjct: 124 ADLSHCNTPSQVRDFTGPSELADCLKDVNVVVIPAGVPRKPGMTRDDLFNINANIVKTLV 183
Query: 432 LSIAQNAPKAIVAIITNPVNSTVPIALKCSRRREC-TTRTACSASPLWTYRAATFVGE 602
++A+N P A + II+NPVNSTVPIA + +++ + + L RA TFV +
Sbjct: 184 EAVAENCPNAFIHIISNPVNSTVPIAAEVLKKKGVYDPKKLFGVTTLDVVRANTFVSQ 241
Score = 69.7 bits (163), Expect = 7e-11
Identities = 35/70 (50%), Positives = 52/70 (74%), Gaps = 2/70 (2%)
Frame = +2
Query: 509 SEVLKKAGVYDPNRVLGVTTLDVSRCH--LRRRDQWRGPNSVAVPVIGGHSGITIIPILS 682
+EVLKK GVYDP ++ GVTTLDV R + + ++ + + V VPVIGGH+GITI+P+LS
Sbjct: 210 AEVLKKKGVYDPKKLFGVTTLDVVRANTFVSQKKNLKLID-VDVPVIGGHAGITILPLLS 268
Query: 683 QCQPALKLSD 712
+ +P++ +D
Sbjct: 269 KTKPSVNFTD 278
Score = 41.5 bits (93), Expect = 0.021
Identities = 22/32 (68%), Positives = 26/32 (81%)
Frame = +1
Query: 160 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAA 255
IGQPL+LL+K +PLV+ L LYDIA V GVAA
Sbjct: 94 IGQPLSLLIKMSPLVSTLHLYDIANV-KGVAA 124
>UniRef50_Q42972 Cluster: Malate dehydrogenase, glyoxysomal
precursor; n=11; Eukaryota|Rep: Malate dehydrogenase,
glyoxysomal precursor - Oryza sativa subsp. japonica
(Rice)
Length = 356
Score = 121 bits (291), Expect = 2e-26
Identities = 64/127 (50%), Positives = 81/127 (63%), Gaps = 1/127 (0%)
Frame = +3
Query: 240 PRRRSDLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIV 419
P +D+SHMNT A V G G +L A+ D+V+IPAGVPRKPGMTRDDLFN NA IV
Sbjct: 82 PGVTADISHMNTGAVVRGFLGQPQLENALTGMDLVIIPAGVPRKPGMTRDDLFNINAGIV 141
Query: 420 RDIALSIAQNAPKAIVAIITNPVNSTVPIALKCSRRR-ECTTRTACSASPLWTYRAATFV 596
R + IA+ P AIV +I+NPVNSTVPIA + ++ + + L RA TFV
Sbjct: 142 RTLCEGIAKCCPNAIVNVISNPVNSTVPIAAEVFKKAGTYDPKRLLGVTTLDVVRANTFV 201
Query: 597 GEINGVD 617
E+ G+D
Sbjct: 202 AEVLGLD 208
Score = 72.9 bits (171), Expect = 7e-12
Identities = 36/63 (57%), Positives = 44/63 (69%), Gaps = 1/63 (1%)
Frame = +2
Query: 509 SEVLKKAGVYDPNRVLGVTTLDVSRCHLRRRDQWR-GPNSVAVPVIGGHSGITIIPILSQ 685
+EV KKAG YDP R+LGVTTLDV R + + P V VPVIGGH+G+TI+P+LSQ
Sbjct: 172 AEVFKKAGTYDPKRLLGVTTLDVVRANTFVAEVLGLDPRDVNVPVIGGHAGVTILPLLSQ 231
Query: 686 CQP 694
P
Sbjct: 232 VNP 234
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/43 (55%), Positives = 27/43 (62%)
Frame = +1
Query: 127 FKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAA 255
FK IGQPLALL+K NPLV+ L LYD+ TPGV A
Sbjct: 45 FKVAILGASGGIGQPLALLMKMNPLVSVLHLYDVVN-TPGVTA 86
>UniRef50_A2QMH9 Cluster: Malate dehydrogenase; n=7; Fungi/Metazoa
group|Rep: Malate dehydrogenase - Aspergillus niger
Length = 340
Score = 118 bits (283), Expect = 2e-25
Identities = 58/128 (45%), Positives = 87/128 (67%), Gaps = 2/128 (1%)
Frame = +3
Query: 240 PRRRSDLSHMNTPAKVSGHKG-PEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASI 416
P +D+SH+NT + V G++ P L A+K +++++IPAGVPRKPGMTRDDLFNTNASI
Sbjct: 61 PGVAADISHINTNSTVKGYEPTPSGLRDALKGSEIILIPAGVPRKPGMTRDDLFNTNASI 120
Query: 417 VRDIALSIAQNAPKAIVAIITNPVNSTVPIALKCSRRREC-TTRTACSASPLWTYRAATF 593
VRD+A + A+ AP+A + +I+NPVNSTVPI + + + + + L RA+ F
Sbjct: 121 VRDLAKAAAEAAPEANILVISNPVNSTVPIVSEVYKSKGVYNPKRLFGVTTLDVVRASRF 180
Query: 594 VGEINGVD 617
+ ++ G +
Sbjct: 181 ISQVKGTN 188
Score = 66.1 bits (154), Expect = 8e-10
Identities = 36/61 (59%), Positives = 42/61 (68%), Gaps = 2/61 (3%)
Frame = +2
Query: 509 SEVLKKAGVYDPNRVLGVTTLDVSRCHLRRRDQWRGPNSV--AVPVIGGHSGITIIPILS 682
SEV K GVY+P R+ GVTTLDV R R Q +G N AV VIGGHSG+TI+P+LS
Sbjct: 152 SEVYKSKGVYNPKRLFGVTTLDVVRAS-RFISQVKGTNPANEAVTVIGGHSGVTIVPLLS 210
Query: 683 Q 685
Q
Sbjct: 211 Q 211
Score = 51.2 bits (117), Expect = 3e-05
Identities = 28/53 (52%), Positives = 35/53 (66%)
Frame = +1
Query: 97 KNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAA 255
++FS ++ + K IGQPL+LL+KQNPLVT LALYDI PGVAA
Sbjct: 14 RSFSASASQASKVAVLGAAGGIGQPLSLLMKQNPLVTDLALYDIRG-GPGVAA 65
>UniRef50_Q6BM17 Cluster: Malate dehydrogenase; n=4; Eukaryota|Rep:
Malate dehydrogenase - Debaryomyces hansenii (Yeast)
(Torulaspora hansenii)
Length = 346
Score = 111 bits (268), Expect = 1e-23
Identities = 60/124 (48%), Positives = 84/124 (67%), Gaps = 6/124 (4%)
Frame = +3
Query: 252 SDLSHMNTPAKVSGHKGPEE-----LSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASI 416
+DLSH+ +PAKV+G++ + + A+ ++D+VVIPAGVPRKPGMTR DLFN NASI
Sbjct: 43 ADLSHICSPAKVTGYQPSSKEDRDTIQKALVNSDLVVIPAGVPRKPGMTRADLFNINASI 102
Query: 417 VRDIALSIAQNAPKAIVAIITNPVNSTVPIALKCSRRREC-TTRTACSASPLWTYRAATF 593
+RDI SI + P A + II+NPVNSTVPIA + ++ + + L + RA TF
Sbjct: 103 IRDIVGSIGKACPNAAILIISNPVNSTVPIAAEVLKKLGVFNPKKLFGVTTLDSVRAETF 162
Query: 594 VGEI 605
+GE+
Sbjct: 163 LGEL 166
Score = 49.6 bits (113), Expect = 8e-05
Identities = 27/60 (45%), Positives = 39/60 (65%), Gaps = 3/60 (5%)
Frame = +2
Query: 509 SEVLKKAGVYDPNRVLGVTTLDVSRCHLRRRDQWRG-PNSVA--VPVIGGHSGITIIPIL 679
+EVLKK GV++P ++ GVTTLD R + + P S+ + VIGGHSG TI+P++
Sbjct: 134 AEVLKKLGVFNPKKLFGVTTLDSVRAETFLGELIKETPTSLKGQISVIGGHSGDTIVPLV 193
Score = 37.9 bits (84), Expect = 0.25
Identities = 19/32 (59%), Positives = 24/32 (75%)
Frame = +1
Query: 160 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAA 255
IGQPL+LLLK NP V+ L+L+D+ GVAA
Sbjct: 13 IGQPLSLLLKLNPQVSELSLFDVVNAN-GVAA 43
>UniRef50_Q9Y7R8 Cluster: Malate dehydrogenase; n=13; Dikarya|Rep:
Malate dehydrogenase - Schizosaccharomyces pombe
(Fission yeast)
Length = 341
Score = 109 bits (262), Expect = 7e-23
Identities = 53/97 (54%), Positives = 68/97 (70%), Gaps = 1/97 (1%)
Frame = +3
Query: 240 PRRRSDLSHMNTPAKVSGHKGPEE-LSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASI 416
P +D+ H+NT + V G+ ++ L A+ ADVV+IPAGVPRKPGMTRDDLF TNASI
Sbjct: 66 PGVAADIGHINTTSNVVGYAPDDKGLEKALNGADVVIIPAGVPRKPGMTRDDLFATNASI 125
Query: 417 VRDIALSIAQNAPKAIVAIITNPVNSTVPIALKCSRR 527
VRD+A + + P+A ++TNPVNSTVPI K R
Sbjct: 126 VRDLAFAAGETCPEAKYLVVTNPVNSTVPIFKKALER 162
Score = 52.0 bits (119), Expect = 1e-05
Identities = 25/59 (42%), Positives = 35/59 (59%), Gaps = 1/59 (1%)
Frame = +2
Query: 512 EVLKKAGVYDPNRVLGVTTLDVSRCHLRRRDQWRGPNSVA-VPVIGGHSGITIIPILSQ 685
+ L++ GV+ P + GVTTLD R G + +PV+GGHSG TI+P+LSQ
Sbjct: 158 KALERVGVHQPKHLFGVTTLDSVRASRFTSQVTNGKAELLHIPVVGGHSGATIVPLLSQ 216
Score = 50.8 bits (116), Expect = 3e-05
Identities = 28/53 (52%), Positives = 34/53 (64%)
Frame = +1
Query: 97 KNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAA 255
++FSTTS R FK IGQPL++LLK N V+ LAL+DI PGVAA
Sbjct: 19 RSFSTTSSRAFKVAVLGAGGGIGQPLSMLLKLNDKVSELALFDIRG-APGVAA 70
>UniRef50_Q6FL22 Cluster: Malate dehydrogenase; n=1; Candida
glabrata|Rep: Malate dehydrogenase - Candida glabrata
(Yeast) (Torulopsis glabrata)
Length = 373
Score = 101 bits (241), Expect = 2e-20
Identities = 52/118 (44%), Positives = 77/118 (65%), Gaps = 1/118 (0%)
Frame = +3
Query: 252 SDLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIA 431
+DLSH+NT A G+ +++ A+K A VVVIPAGVPR+PG+TRDDLF NA IV+++
Sbjct: 43 TDLSHINTNADCVGYS-TDDIGQALKGAAVVVIPAGVPRRPGITRDDLFKLNAGIVKNLV 101
Query: 432 LSIAQNAPKAIVAIITNPVNSTVPIALKCSRR-RECTTRTACSASPLWTYRAATFVGE 602
++A++ P A + II+NPVNS +P+A++ +R + L RA TF+ E
Sbjct: 102 SNVAKHCPNARLLIISNPVNSLIPVAVETLKRCGVFQAGNVMGVTTLDLVRAETFLAE 159
Score = 37.5 bits (83), Expect = 0.33
Identities = 18/31 (58%), Positives = 24/31 (77%)
Frame = +1
Query: 160 IGQPLALLLKQNPLVTRLALYDIAPVTPGVA 252
+GQPL+LLLK N +++ LALYDI + GVA
Sbjct: 13 VGQPLSLLLKLNTMISELALYDI-KLAEGVA 42
>UniRef50_P22133 Cluster: Malate dehydrogenase, cytoplasmic; n=3;
Saccharomycetaceae|Rep: Malate dehydrogenase,
cytoplasmic - Saccharomyces cerevisiae (Baker's yeast)
Length = 377
Score = 100 bits (240), Expect = 3e-20
Identities = 56/127 (44%), Positives = 74/127 (58%), Gaps = 8/127 (6%)
Frame = +3
Query: 252 SDLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIA 431
+DLSH++TP VS H + + +A +VVIPAGVPRKPGMTRDDLFN NA I+ +
Sbjct: 68 ADLSHIDTPISVSSHSPAGGIENCLHNASIVVIPAGVPRKPGMTRDDLFNVNAGIISQLG 127
Query: 432 LSIAQ--NAPKAIVAIITNPVNSTVPIALK------CSRRRECTTRTACSASPLWTYRAA 587
SIA+ + K V +I+NPVNS VP+ + R R + L RA+
Sbjct: 128 DSIAECCDLSKVFVLVISNPVNSLVPVMVSNILKNHPQSRNSGIERRIMGVTKLDIVRAS 187
Query: 588 TFVGEIN 608
TF+ EIN
Sbjct: 188 TFLREIN 194
Score = 40.3 bits (90), Expect = 0.048
Identities = 28/62 (45%), Positives = 37/62 (59%), Gaps = 7/62 (11%)
Frame = +2
Query: 548 RVLGVTTLDVSRCH--LRRRDQWRG----PNSVA-VPVIGGHSGITIIPILSQCQPALKL 706
R++GVT LD+ R LR + G NS+ VPVIGGHSG TIIP+ SQ +L
Sbjct: 174 RIMGVTKLDIVRASTFLREINIESGLTPRVNSMPDVPVIGGHSGETIIPLFSQSNFLSRL 233
Query: 707 SD 712
++
Sbjct: 234 NE 235
>UniRef50_Q9VU29 Cluster: Malate dehydrogenase; n=5;
Protostomia|Rep: Malate dehydrogenase - Drosophila
melanogaster (Fruit fly)
Length = 347
Score = 98.3 bits (234), Expect = 2e-19
Identities = 53/122 (43%), Positives = 72/122 (59%), Gaps = 1/122 (0%)
Frame = +3
Query: 255 DLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIAL 434
DLSH+NT A V +G L A+ AD+VVIPAG+PRKPGM R+DL + NAS+ ++A
Sbjct: 70 DLSHINTRASVCPFEGKNGLKKAMDKADIVVIPAGLPRKPGMKREDLVDVNASVACEVAF 129
Query: 435 SIAQNAPKAIVAIITNPVNSTVPI-ALKCSRRRECTTRTACSASPLWTYRAATFVGEING 611
+ ++ P A++A ITNP+N VPI A + + L RA TFV +I
Sbjct: 130 AASEVCPGAMLAFITNPINVIVPIVATILKAKGTYDPNRLFGVTTLDVVRAQTFVADILN 189
Query: 612 VD 617
VD
Sbjct: 190 VD 191
Score = 77.0 bits (181), Expect = 4e-13
Identities = 38/70 (54%), Positives = 45/70 (64%), Gaps = 1/70 (1%)
Frame = +2
Query: 515 VLKKAGVYDPNRVLGVTTLDVSRCHLRRRDQWR-GPNSVAVPVIGGHSGITIIPILSQCQ 691
+LK G YDPNR+ GVTTLDV R D P V +PVIGGH+G TI+PILSQC
Sbjct: 157 ILKAKGTYDPNRLFGVTTLDVVRAQTFVADILNVDPQKVNIPVIGGHTGRTILPILSQCD 216
Query: 692 PALKLSDRPR 721
P K +D+ R
Sbjct: 217 PPFKGTDKER 226
Score = 39.1 bits (87), Expect = 0.11
Identities = 19/40 (47%), Positives = 23/40 (57%)
Frame = +1
Query: 121 RNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVT 240
R K IGQPL+LLLK NP ++ L+LYDI T
Sbjct: 26 RGLKVAVVGSVGGIGQPLSLLLKHNPQISTLSLYDIKNTT 65
>UniRef50_A3BMG8 Cluster: Putative uncharacterized protein; n=3;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 405
Score = 95.5 bits (227), Expect = 1e-18
Identities = 43/68 (63%), Positives = 52/68 (76%)
Frame = +3
Query: 252 SDLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIA 431
+DL H NTPAKV+G G EEL+ + DVVVIPAGVPRKPGMTRDDLF NA IVR++
Sbjct: 119 ADLGHCNTPAKVAGFTGKEELAGCLAGVDVVVIPAGVPRKPGMTRDDLFGINAGIVRELV 178
Query: 432 LSIAQNAP 455
++A +AP
Sbjct: 179 EAVADHAP 186
Score = 39.5 bits (88), Expect = 0.083
Identities = 21/32 (65%), Positives = 25/32 (78%)
Frame = +1
Query: 160 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAA 255
IGQPL+LL+K +PLV+ L LYDIA V GV A
Sbjct: 89 IGQPLSLLVKMSPLVSALHLYDIANV-DGVTA 119
>UniRef50_Q4Q3J3 Cluster: Malate dehydrogenase, putative; n=3;
Leishmania|Rep: Malate dehydrogenase, putative -
Leishmania major
Length = 331
Score = 95.1 bits (226), Expect = 2e-18
Identities = 50/122 (40%), Positives = 76/122 (62%), Gaps = 1/122 (0%)
Frame = +3
Query: 255 DLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIAL 434
DLSH KV+G+ + + A+ AD+V++ AG+PR+PGMT DDLFNTNA V +++
Sbjct: 51 DLSHFPRKVKVTGYP-TKWIHKALDGADLVLMSAGMPRRPGMTHDDLFNTNALTVNELSA 109
Query: 435 SIAQNAPKAIVAIITNPVNSTVPIALKCSRRREC-TTRTACSASPLWTYRAATFVGEING 611
++A+ APK+++AII+NP+NS VP+A + +R R L RA +G+ G
Sbjct: 110 AVARYAPKSVLAIISNPLNSMVPVAAETLQRAGVYDPRKLFGIISLNMMRARKMLGDFTG 169
Query: 612 VD 617
D
Sbjct: 170 QD 171
Score = 56.4 bits (130), Expect = 7e-07
Identities = 26/59 (44%), Positives = 39/59 (66%), Gaps = 1/59 (1%)
Frame = +2
Query: 509 SEVLKKAGVYDPNRVLGVTTLDVSRCHLRRRD-QWRGPNSVAVPVIGGHSGITIIPILS 682
+E L++AGVYDP ++ G+ +L++ R D + P + VPVIGGHSG TI+P+ S
Sbjct: 135 AETLQRAGVYDPRKLFGIISLNMMRARKMLGDFTGQDPEMLDVPVIGGHSGQTIVPLFS 193
Score = 35.9 bits (79), Expect = 1.0
Identities = 19/34 (55%), Positives = 20/34 (58%)
Frame = +1
Query: 127 FKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDI 228
FK IGQPLAL L QN V+ LALYDI
Sbjct: 9 FKVTVLGASGAIGQPLALALVQNKRVSELALYDI 42
>UniRef50_Q75AT4 Cluster: ADL164Cp; n=2; Saccharomycetales|Rep:
ADL164Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 381
Score = 95.1 bits (226), Expect = 2e-18
Identities = 50/95 (52%), Positives = 64/95 (67%), Gaps = 7/95 (7%)
Frame = +3
Query: 252 SDLSHMNTPAKVSGH-----KGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASI 416
+DLSH+NTP +VS H + E L A+ A VVVIPAGVPRKPGMTRDDL N NA I
Sbjct: 75 ADLSHVNTPVEVSHHVPSSREDEEALREALTGASVVVIPAGVPRKPGMTRDDLININAGI 134
Query: 417 VRDIALSIAQ--NAPKAIVAIITNPVNSTVPIALK 515
++ +A IA + K V +I+NPVNS VP+ ++
Sbjct: 135 IKTLAKGIAGACDLEKVFVLVISNPVNSLVPVMVR 169
Score = 45.2 bits (102), Expect = 0.002
Identities = 27/61 (44%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Frame = +2
Query: 548 RVLGVTTLDVSRCHLRRRDQWRGPNSV-AVPVIGGHSGITIIPILSQCQPALKLSDRPRS 724
RV GVT LD+ R R N V +VPVIGGHSG TI+P+ Q L+ S R
Sbjct: 188 RVFGVTQLDMVRASAFVRSLGELGNEVPSVPVIGGHSGETILPLFGPVQQRLQFSLEQRK 247
Query: 725 R 727
+
Sbjct: 248 K 248
>UniRef50_P32419 Cluster: Malate dehydrogenase, peroxisomal; n=24;
Eukaryota|Rep: Malate dehydrogenase, peroxisomal -
Saccharomyces cerevisiae (Baker's yeast)
Length = 343
Score = 94.3 bits (224), Expect = 3e-18
Identities = 43/91 (47%), Positives = 64/91 (70%)
Frame = +3
Query: 255 DLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIAL 434
DLSH+NT + G+ + + + +A VV+IPAGVPRKPG+TRDDLF NA IV+ +
Sbjct: 44 DLSHINTNSSCVGYD-KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVT 102
Query: 435 SIAQNAPKAIVAIITNPVNSTVPIALKCSRR 527
++ + AP A + +I+NPVNS VPIA++ ++
Sbjct: 103 AVGKFAPNARILVISNPVNSLVPIAVETLKK 133
Score = 40.7 bits (91), Expect = 0.036
Identities = 28/69 (40%), Positives = 37/69 (53%), Gaps = 12/69 (17%)
Frame = +2
Query: 512 EVLKKAGVYDPNRVLGVTTLDVSRCH--------LRR----RDQWRGPNSVAVPVIGGHS 655
E LKK G + P V+GVT LD+ R L+ ++Q + V VIGGHS
Sbjct: 129 ETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVTVIGGHS 188
Query: 656 GITIIPILS 682
G TIIPI++
Sbjct: 189 GETIIPIIT 197
Score = 37.1 bits (82), Expect = 0.44
Identities = 16/23 (69%), Positives = 20/23 (86%)
Frame = +1
Query: 160 IGQPLALLLKQNPLVTRLALYDI 228
+GQPL+LLLK +P V+ LALYDI
Sbjct: 13 VGQPLSLLLKLSPYVSELALYDI 35
>UniRef50_Q4QDF0 Cluster: Glycosomal malate dehydrogenase; n=9;
Trypanosomatidae|Rep: Glycosomal malate dehydrogenase -
Leishmania major
Length = 322
Score = 93.5 bits (222), Expect = 5e-18
Identities = 56/125 (44%), Positives = 71/125 (56%), Gaps = 8/125 (6%)
Frame = +3
Query: 252 SDLSHM-NTPAKVS------GHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNA 410
+DLSH+ N +V GHK L+ K DV V+ AGVPRKPGMTRDDLF NA
Sbjct: 44 ADLSHVDNAGVQVKFAEGKIGHKRDPALAELAKGVDVFVMVAGVPRKPGMTRDDLFKINA 103
Query: 411 SIVRDIALSIAQNAPKAIVAIITNPVNSTVPIALKCSRRRECTTRT-ACSASPLWTYRAA 587
I+ D+ L+ A ++PKA+ I+TNPVNSTV IA + + R S L RA
Sbjct: 104 GIILDLVLTCASSSPKAVFCIVTNPVNSTVAIAAEALKSLGVYDRNRLLGVSLLDGLRAT 163
Query: 588 TFVGE 602
F+ E
Sbjct: 164 CFINE 168
Score = 52.0 bits (119), Expect = 1e-05
Identities = 31/65 (47%), Positives = 41/65 (63%), Gaps = 3/65 (4%)
Frame = +2
Query: 500 AYCSEVLKKAGVYDPNRVLGVTTLDVSR--CHLRRRDQWRGPNSVA-VPVIGGHSGITII 670
A +E LK GVYD NR+LGV+ LD R C + ++ R P V+ VPV+GGHS TI+
Sbjct: 134 AIAAEALKSLGVYDRNRLLGVSLLDGLRATCFI---NEARKPLVVSQVPVVGGHSDTTIV 190
Query: 671 PILSQ 685
P+ Q
Sbjct: 191 PLFYQ 195
>UniRef50_A7TSF5 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 387
Score = 88.6 bits (210), Expect = 1e-16
Identities = 43/85 (50%), Positives = 60/85 (70%)
Frame = +3
Query: 252 SDLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIA 431
+DLSH+NT K+S H + L ++ D+++V+IPAGVPRKPGMTRDDLFN NA I++ IA
Sbjct: 89 ADLSHVNTNMKLSLH---DNLRDSLVDSNLVIIPAGVPRKPGMTRDDLFNINAGIIKGIA 145
Query: 432 LSIAQNAPKAIVAIITNPVNSTVPI 506
+ V +I+NPVNS +P+
Sbjct: 146 QELNTIDSTPFVLLISNPVNSLLPV 170
Score = 37.9 bits (84), Expect = 0.25
Identities = 15/19 (78%), Positives = 17/19 (89%)
Frame = +2
Query: 632 VPVIGGHSGITIIPILSQC 688
VPVIGGHSG TI+P+LS C
Sbjct: 215 VPVIGGHSGDTILPVLSNC 233
>UniRef50_Q9VU28 Cluster: Malate dehydrogenase; n=3; Sophophora|Rep:
Malate dehydrogenase - Drosophila melanogaster (Fruit
fly)
Length = 349
Score = 87.4 bits (207), Expect = 3e-16
Identities = 46/118 (38%), Positives = 68/118 (57%), Gaps = 1/118 (0%)
Frame = +3
Query: 252 SDLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIA 431
+DLSH++ KV G G +EL +A+ ADVVV+ AG+PR PGM RD L N ++ +A
Sbjct: 64 TDLSHISQTGKVIGFTGEKELESAVSGADVVVVAAGMPRLPGMQRDHLMAANGNVAVKVA 123
Query: 432 LSIAQNAPKAIVAIITNPVNSTVPIALK-CSRRRECTTRTACSASPLWTYRAATFVGE 602
+I+ +P+A +A ITNPVN VP A + +R + L R+ F+G+
Sbjct: 124 TAISNASPRAHLAFITNPVNMIVPAAAEVLMAHGTFDSRRLFGITTLDVVRSKKFIGD 181
Score = 68.1 bits (159), Expect = 2e-10
Identities = 32/63 (50%), Positives = 42/63 (66%), Gaps = 1/63 (1%)
Frame = +2
Query: 509 SEVLKKAGVYDPNRVLGVTTLDVSRCHLRRRDQWR-GPNSVAVPVIGGHSGITIIPILSQ 685
+EVL G +D R+ G+TTLDV R D P+ V +PVIGGH+GITI+P++SQ
Sbjct: 150 AEVLMAHGTFDSRRLFGITTLDVVRSKKFIGDSMNISPDDVNIPVIGGHAGITILPLISQ 209
Query: 686 CQP 694
CQP
Sbjct: 210 CQP 212
>UniRef50_A7TL95 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 365
Score = 85.8 bits (203), Expect = 1e-15
Identities = 37/88 (42%), Positives = 61/88 (69%), Gaps = 1/88 (1%)
Frame = +3
Query: 255 DLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIAL 434
DLSH+NT + G+ E+ ++ +++V++ AG+PRKPGMTRDDLF NA I++++ +
Sbjct: 45 DLSHINTNSDSEGYNKDEDFKNLLEGSELVIVTAGIPRKPGMTRDDLFKINAKIIQNLTV 104
Query: 435 SIAQNAP-KAIVAIITNPVNSTVPIALK 515
A+ AP + II+NPVNS +P+ ++
Sbjct: 105 KYAKFAPVHCKLLIISNPVNSLIPVVIE 132
Score = 47.2 bits (107), Expect = 4e-04
Identities = 22/31 (70%), Positives = 26/31 (83%)
Frame = +1
Query: 160 IGQPLALLLKQNPLVTRLALYDIAPVTPGVA 252
IGQPL+LLLK NP V+ LALYDI+ +T GVA
Sbjct: 13 IGQPLSLLLKLNPYVSDLALYDISDITAGVA 43
>UniRef50_Q6CP51 Cluster: Similar to sp|P22133 Saccharomyces
cerevisiae YOL126c MDH2 malate dehydrogenase; n=1;
Kluyveromyces lactis|Rep: Similar to sp|P22133
Saccharomyces cerevisiae YOL126c MDH2 malate
dehydrogenase - Kluyveromyces lactis (Yeast) (Candida
sphaerica)
Length = 404
Score = 84.6 bits (200), Expect = 2e-15
Identities = 47/130 (36%), Positives = 74/130 (56%), Gaps = 10/130 (7%)
Frame = +3
Query: 252 SDLSHMNTPAKVSGHKGPEE---LSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVR 422
+DLSH++TP + H + + + +A VV+IPAGVPRKPGM+RDDL NA I++
Sbjct: 99 ADLSHIDTPITTTAHYPDDSNGGIGQCLSNASVVIIPAGVPRKPGMSRDDLIGVNAKIIK 158
Query: 423 DIALSIAQ--NAPKAIVAIITNPVNSTVPIALKCSRRRECTTRTACSA-----SPLWTYR 581
+ IA+ + K V +I+NP+NS VP+ R + + + + L R
Sbjct: 159 SLGEDIAKYCDLNKVHVLVISNPINSLVPLLTNTLIRSDANGNSNIESRVYGITQLDLVR 218
Query: 582 AATFVGEING 611
++TFV ++NG
Sbjct: 219 SSTFVQQLNG 228
Score = 42.7 bits (96), Expect = 0.009
Identities = 21/48 (43%), Positives = 32/48 (66%), Gaps = 2/48 (4%)
Frame = +2
Query: 545 NRVLGVTTLDVSRCH--LRRRDQWRGPNSVAVPVIGGHSGITIIPILS 682
+RV G+T LD+ R +++ + ++ S +PVIGGHSG TIIP+ S
Sbjct: 206 SRVYGITQLDLVRSSTFVQQLNGFKSNTSPVIPVIGGHSGDTIIPVFS 253
>UniRef50_UPI00005A0834 Cluster: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor; n=1; Canis lupus
familiaris|Rep: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor - Canis
familiaris
Length = 245
Score = 83.0 bits (196), Expect = 7e-15
Identities = 40/84 (47%), Positives = 55/84 (65%), Gaps = 1/84 (1%)
Frame = +3
Query: 363 PRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIALKCSRRREC-T 539
PRKPGMTRDDLFNTNAS+V + AQ+ P+A++ +I+NPVNST+PIA + ++
Sbjct: 61 PRKPGMTRDDLFNTNASVVATPTAACAQHCPEAMICVISNPVNSTIPIATEVFKKHGAYD 120
Query: 540 TRTACSASPLWTYRAATFVGEING 611
+ L RA TF+ E+NG
Sbjct: 121 PNKIFRVTTLDIVRANTFIAELNG 144
>UniRef50_Q5ENS5 Cluster: Malate dehydrogenase; n=1; Heterocapsa
triquetra|Rep: Malate dehydrogenase - Heterocapsa
triquetra (Dinoflagellate)
Length = 402
Score = 79.4 bits (187), Expect = 8e-14
Identities = 44/121 (36%), Positives = 63/121 (52%), Gaps = 6/121 (4%)
Frame = +3
Query: 252 SDLSHMNTPAKVSGH------KGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNAS 413
+DL H+ A V G+ K + L + +V+IPAG+PRKPG TRDDLF NA
Sbjct: 126 TDLGHLEKKAAVKGYVMEVGQKPVDNLEECLTGCHLVLIPAGMPRKPGQTRDDLFKINAD 185
Query: 414 IVRDIALSIAQNAPKAIVAIITNPVNSTVPIALKCSRRRECTTRTACSASPLWTYRAATF 593
I + I + A+ P A++ +I NPVNS VP + +++ + L RA F
Sbjct: 186 IAKGIVEACAKYCPDAMLGMIVNPVNSVVPAMAELYKKKGLDPMKIVGITTLDVVRANKF 245
Query: 594 V 596
V
Sbjct: 246 V 246
Score = 54.8 bits (126), Expect = 2e-06
Identities = 28/59 (47%), Positives = 40/59 (67%)
Frame = +2
Query: 509 SEVLKKAGVYDPNRVLGVTTLDVSRCHLRRRDQWRGPNSVAVPVIGGHSGITIIPILSQ 685
+E+ KK G+ DP +++G+TTLDV R + P+ V VPVIGGH+G TI+P+ SQ
Sbjct: 218 AELYKKKGL-DPMKIVGITTLDVVRANKFVVRLPAPPDRVNVPVIGGHAGTTILPLFSQ 275
>UniRef50_Q86DP2 Cluster: Malate dehydrogenase; n=11; Fungi/Metazoa
group|Rep: Malate dehydrogenase - Plicopurpura patula
Length = 229
Score = 77.8 bits (183), Expect = 3e-13
Identities = 40/76 (52%), Positives = 48/76 (63%), Gaps = 1/76 (1%)
Frame = +2
Query: 509 SEVLKKAGVYDPNRVLGVTTLDVSRCHLRRRD-QWRGPNSVAVPVIGGHSGITIIPILSQ 685
SEVLKK GVYDP RV GVTTLDV R + + + VPVIGGHSG+TIIP++SQ
Sbjct: 41 SEVLKKRGVYDPKRVFGVTTLDVVRSNTFIAEAKGLDVTKTNVPVIGGHSGVTIIPLISQ 100
Query: 686 CQPALKLSDRPRSRRS 733
C P + R + S
Sbjct: 101 CTPPVSFPTEEREKLS 116
Score = 68.1 bits (159), Expect = 2e-10
Identities = 37/79 (46%), Positives = 49/79 (62%), Gaps = 1/79 (1%)
Frame = +3
Query: 390 DLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIALKCSRRREC-TTRTACSASP 566
DLFNTNA IVRD+ IA+ P A++ IITNPVNSTVPIA + ++R + +
Sbjct: 1 DLFNTNAGIVRDLTDRIAKVCPTAMLGIITNPVNSTVPIASEVLKKRGVYDPKRVFGVTT 60
Query: 567 LWTYRAATFVGEINGVDRT 623
L R+ TF+ E G+D T
Sbjct: 61 LDVVRSNTFIAEAKGLDVT 79
>UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3;
Actinomycetales|Rep: Lactate/malate dehydrogenase -
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 330
Score = 73.7 bits (173), Expect = 4e-12
Identities = 42/97 (43%), Positives = 58/97 (59%)
Frame = +3
Query: 324 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 503
I DA +V+I AGVPRKPGM+R DL TNA IVR +A +IA+ AP A+V +++NP++
Sbjct: 85 IADASIVIITAGVPRKPGMSRMDLLETNARIVRGVAENIAKYAPSAVVIVVSNPLDEMTA 144
Query: 504 IALKCSRRRECTTRTACSASPLWTYRAATFVGEINGV 614
+ + + R A L T R + FV E GV
Sbjct: 145 LTQLVTGFPK--NRVMGQAGMLDTARFSHFVAEELGV 179
>UniRef50_Q64P62 Cluster: Malate dehydrogenase; n=28;
Bacteroidetes|Rep: Malate dehydrogenase - Bacteroides
fragilis
Length = 313
Score = 70.9 bits (166), Expect = 3e-11
Identities = 30/66 (45%), Positives = 49/66 (74%)
Frame = +3
Query: 318 AAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNST 497
A ++DVVVI +G+PRKPGMTR++L NA IV+ +A ++ + +P AI+ +I+NP+++
Sbjct: 67 AQTANSDVVVITSGIPRKPGMTREELIGVNAGIVKSVAENLLKYSPNAIIVVISNPMDTM 126
Query: 498 VPIALK 515
+ALK
Sbjct: 127 TYLALK 132
>UniRef50_Q8TWG5 Cluster: Malate dehydrogenase; n=2;
Euryarchaeota|Rep: Malate dehydrogenase - Methanopyrus
kandleri
Length = 317
Score = 70.5 bits (165), Expect = 4e-11
Identities = 32/64 (50%), Positives = 45/64 (70%)
Frame = +3
Query: 330 DADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIA 509
DADV+V+ AG+PRKPG TR DL NA+I++ +A+ P+AIV ++TNPV+ +A
Sbjct: 73 DADVIVMTAGIPRKPGQTRLDLTKDNAAIIKKYLEGVAEENPEAIVLVVTNPVDVLTYVA 132
Query: 510 LKCS 521
LK S
Sbjct: 133 LKVS 136
>UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Rep:
Malate dehydrogenase - Brucella melitensis
Length = 320
Score = 70.1 bits (164), Expect = 5e-11
Identities = 31/61 (50%), Positives = 43/61 (70%)
Frame = +3
Query: 318 AAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNST 497
AAI+ ADVV++ AGVPRKPGM+RDDL N ++ + I + AP+A V ITNP+++
Sbjct: 67 AAIEGADVVIVTAGVPRKPGMSRDDLLGINLKVMEQVGAGIKKYAPEAFVICITNPLDAM 126
Query: 498 V 500
V
Sbjct: 127 V 127
>UniRef50_A6Q7S2 Cluster: Malate dehydrogenase, NAD-dependent; n=1;
Sulfurovum sp. NBC37-1|Rep: Malate dehydrogenase,
NAD-dependent - Sulfurovum sp. (strain NBC37-1)
Length = 320
Score = 69.7 bits (163), Expect = 7e-11
Identities = 38/95 (40%), Positives = 58/95 (61%)
Frame = +3
Query: 231 ACDPRRRSDLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNA 410
A D + ++ + +T K + KGPE++ + DVV+I AG PR PGM+RDDL NA
Sbjct: 46 ALDMSQAANAARQHTIVKAA--KGPEDMEGS----DVVIITAGAPRTPGMSRDDLLFKNA 99
Query: 411 SIVRDIALSIAQNAPKAIVAIITNPVNSTVPIALK 515
IV+ + I + AP AIV +++NP++ +ALK
Sbjct: 100 DIVKCYSREIKEYAPDAIVIVVSNPLDVMTYVALK 134
>UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2;
Toxoplasma gondii|Rep: Mitochondrial
malate-dehydrogenase - Toxoplasma gondii
Length = 470
Score = 69.7 bits (163), Expect = 7e-11
Identities = 32/63 (50%), Positives = 43/63 (68%)
Frame = +3
Query: 318 AAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNST 497
+ +KDADV+++ AGVPRKPGM+RDDL NA I+ + +I Q P A V ITNP++
Sbjct: 221 SVLKDADVIIVTAGVPRKPGMSRDDLLAINAKIMGQVGEAIKQYCPNAFVICITNPLDVM 280
Query: 498 VPI 506
V I
Sbjct: 281 VYI 283
>UniRef50_A7I2F1 Cluster: Malate dehydrogenase; n=1; Campylobacter
hominis ATCC BAA-381|Rep: Malate dehydrogenase -
Campylobacter hominis (strain ATCC BAA-381 / LMG 19568 /
NCTC 13146 /CH001A)
Length = 297
Score = 68.5 bits (160), Expect = 2e-10
Identities = 40/96 (41%), Positives = 59/96 (61%), Gaps = 4/96 (4%)
Frame = +3
Query: 246 RRSDLSHM----NTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNAS 413
R DLSH+ N ++SG E L +K++D+VVI AG R+ G +R DL N NA
Sbjct: 42 RALDLSHLASVYNKKTEISG-SSDETL---LKNSDIVVITAGKTRQAGQSRADLLNDNAK 97
Query: 414 IVRDIALSIAQNAPKAIVAIITNPVNSTVPIALKCS 521
I+ A ++A+ AP+AI+ +ITNPV++ +A K S
Sbjct: 98 IISSCAKNVAKYAPEAIIILITNPVDTLAFVAYKAS 133
>UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|Rep:
Malate dehydrogenase 1 - Aquifex aeolicus
Length = 335
Score = 68.5 bits (160), Expect = 2e-10
Identities = 45/117 (38%), Positives = 65/117 (55%), Gaps = 2/117 (1%)
Frame = +3
Query: 258 LSHMNTPAKVSGHK-GPE-ELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIA 431
L+ M+ A+V G+ PE E ++ +D+VVI AG PR+PGM+R+DL N I+ IA
Sbjct: 59 LAAMDIDARVEGYTVTPEGEGYEPLEGSDIVVITAGFPRRPGMSREDLLEANIRIISVIA 118
Query: 432 LSIAQNAPKAIVAIITNPVNSTVPIALKCSRRRECTTRTACSASPLWTYRAATFVGE 602
I + AP AIV ++TNPV+ +A K + R A L + R TF+ E
Sbjct: 119 DRIKRYAPDAIVIVVTNPVDVMTYVAYKLLNFPK--NRVMGMAGVLDSARFKTFISE 173
>UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular
organisms|Rep: Malate dehydrogenase - Silicibacter
pomeroyi
Length = 320
Score = 66.9 bits (156), Expect = 5e-10
Identities = 30/61 (49%), Positives = 40/61 (65%)
Frame = +3
Query: 318 AAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNST 497
A I ADV ++ AGVPRKPGM+RDDL N +++ + I NAP A V ITNP+++
Sbjct: 67 ADIAGADVCIVTAGVPRKPGMSRDDLLGINLKVMKSVGEGIRDNAPDAFVICITNPLDAM 126
Query: 498 V 500
V
Sbjct: 127 V 127
>UniRef50_A7GYI6 Cluster: Lactate/malate dehydrogenase, NAD binding
domain protein; n=2; Campylobacter|Rep: Lactate/malate
dehydrogenase, NAD binding domain protein -
Campylobacter curvus 525.92
Length = 297
Score = 66.1 bits (154), Expect = 8e-10
Identities = 33/68 (48%), Positives = 46/68 (67%)
Frame = +3
Query: 318 AAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNST 497
A I+ +D+VV+ AG PRK G TR+DL NA +V+ A +IA+ AP AIV I+TNP++
Sbjct: 65 ALIEASDIVVVTAGSPRKEGQTREDLLLKNAQVVKQTAQNIAKFAPNAIVIIVTNPLDVM 124
Query: 498 VPIALKCS 521
V L+ S
Sbjct: 125 VWTVLRYS 132
>UniRef50_Q3J7E7 Cluster: Malate dehydrogenase; n=5;
Gammaproteobacteria|Rep: Malate dehydrogenase -
Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
Length = 311
Score = 66.1 bits (154), Expect = 8e-10
Identities = 37/95 (38%), Positives = 60/95 (63%)
Frame = +3
Query: 207 QAGFIRHSACDPRRRSDLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTR 386
Q G + +A D ++ + L + A+V+G E I D+D+VVI AG PRKPGM+R
Sbjct: 37 QEGVAQGAALDIQQSAPLFDFD--ARVTGSTNYE----LIADSDLVVITAGKPRKPGMSR 90
Query: 387 DDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 491
D+ ++N I+ DI ++ + AP+++V I+TNPV+
Sbjct: 91 SDVLDSNLPIITDIMNNVMRFAPQSLVMIVTNPVD 125
>UniRef50_O08349 Cluster: Malate dehydrogenase; n=1; Archaeoglobus
fulgidus|Rep: Malate dehydrogenase - Archaeoglobus
fulgidus
Length = 294
Score = 66.1 bits (154), Expect = 8e-10
Identities = 26/56 (46%), Positives = 44/56 (78%)
Frame = +3
Query: 324 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 491
+K ++++V+ AG+ RKPGMTR DL + NA I++DIA I +NAP++ + ++TNP++
Sbjct: 67 LKGSEIIVVTAGLARKPGMTRLDLAHKNAGIIKDIAKKIVENAPESKILVVTNPMD 122
>UniRef50_Q6VVP7 Cluster: Malate dehydrogenase; n=6; Plasmodium|Rep:
Malate dehydrogenase - Plasmodium falciparum
Length = 313
Score = 65.7 bits (153), Expect = 1e-09
Identities = 35/89 (39%), Positives = 51/89 (57%)
Frame = +3
Query: 255 DLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIAL 434
DL H +T V+ + IKDAD++VI AGV RK GMTR+DL N I++ +A
Sbjct: 44 DLKHFSTILGVNRNILGTNQIEDIKDADIIVITAGVQRKEGMTREDLIGVNGKIMKSVAE 103
Query: 435 SIAQNAPKAIVAIITNPVNSTVPIALKCS 521
S+ + KA V ++NP++ V + K S
Sbjct: 104 SVKLHCSKAFVICVSNPLDIMVNVFHKFS 132
>UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter
hepaticus|Rep: Malate dehydrogenase - Helicobacter
hepaticus
Length = 315
Score = 65.3 bits (152), Expect = 1e-09
Identities = 31/97 (31%), Positives = 60/97 (61%), Gaps = 2/97 (2%)
Frame = +3
Query: 324 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 503
I +++VV+I AG PR P MTR+DL NASI+++I+ ++A+ AP++++ +++NP+++
Sbjct: 70 IAESEVVIITAGFPRTPNMTRNDLLLKNASIIQEISSNVARIAPQSLLIVVSNPLDAMCL 129
Query: 504 IALKCSR--RRECTTRTACSASPLWTYRAATFVGEIN 608
+A + S+ + S TY + +G+ N
Sbjct: 130 VAKQWSKFEKERVIGMAGILDSARLTYESKVMLGDFN 166
>UniRef50_P16115 Cluster: L-lactate dehydrogenase; n=4;
Thermotogaceae|Rep: L-lactate dehydrogenase - Thermotoga
maritima
Length = 319
Score = 64.5 bits (150), Expect = 3e-09
Identities = 29/66 (43%), Positives = 46/66 (69%)
Frame = +3
Query: 318 AAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNST 497
A +K +DVV++ AGVP+KPG TR L NA ++++IA ++++ AP +IV ++TNPV+
Sbjct: 63 ADLKGSDVVIVAAGVPQKPGETRLQLLGRNARVMKEIARNVSKYAPDSIVIVVTNPVDVL 122
Query: 498 VPIALK 515
LK
Sbjct: 123 TYFFLK 128
>UniRef50_Q8ZVB2 Cluster: Malate dehydrogenase; n=14;
Thermoprotei|Rep: Malate dehydrogenase - Pyrobaculum
aerophilum
Length = 309
Score = 64.1 bits (149), Expect = 3e-09
Identities = 32/90 (35%), Positives = 55/90 (61%), Gaps = 1/90 (1%)
Frame = +3
Query: 255 DLSHMNTPAKVS-GHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIA 431
D++HM++ + + G E I+ +D++++ AG+PRKPGMTR+ L NA IV +I
Sbjct: 43 DMNHMSSILGLDVEYVGSNEYKD-IEGSDLIIVTAGLPRKPGMTREQLLEANAKIVAEIG 101
Query: 432 LSIAQNAPKAIVAIITNPVNSTVPIALKCS 521
I + AP +IV + TNP+++ + K +
Sbjct: 102 REIKKYAPDSIVILTTNPLDAMTYVMWKAT 131
>UniRef50_Q017A6 Cluster: Malate dehydrogenase; n=2; cellular
organisms|Rep: Malate dehydrogenase - Ostreococcus tauri
Length = 477
Score = 63.7 bits (148), Expect = 4e-09
Identities = 33/66 (50%), Positives = 42/66 (63%), Gaps = 1/66 (1%)
Frame = +2
Query: 509 SEVLKKAGVYDPNRVLGVTTLDVSRCHLRRRDQWRGPNS-VAVPVIGGHSGITIIPILSQ 685
+EVLK G YDP ++ GVTTLDV R ++ S V VPV+GGH+GITI+P+ SQ
Sbjct: 45 AEVLKAKGKYDPKKLFGVTTLDVVRAKTFYAEKAGLETSKVDVPVVGGHAGITILPLFSQ 104
Query: 686 CQPALK 703
P K
Sbjct: 105 ATPQAK 110
Score = 61.7 bits (143), Expect = 2e-08
Identities = 33/81 (40%), Positives = 48/81 (59%), Gaps = 1/81 (1%)
Frame = +3
Query: 378 MTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIALKCSRRR-ECTTRTAC 554
MTRDDLF N IV+ + +IA N P A++ +I+NPVNSTVPIA + + + + +
Sbjct: 1 MTRDDLFAINGGIVKGLVEAIADNCPNAMINMISNPVNSTVPIAAEVLKAKGKYDPKKLF 60
Query: 555 SASPLWTYRAATFVGEINGVD 617
+ L RA TF E G++
Sbjct: 61 GVTTLDVVRAKTFYAEKAGLE 81
>UniRef50_Q18WQ6 Cluster: Malate dehydrogenase, NAD-dependent; n=2;
Desulfitobacterium hafniense|Rep: Malate dehydrogenase,
NAD-dependent - Desulfitobacterium hafniense (strain
DCB-2)
Length = 320
Score = 62.1 bits (144), Expect = 1e-08
Identities = 27/62 (43%), Positives = 43/62 (69%)
Frame = +3
Query: 330 DADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIA 509
D+DVVVI AG+ RKPGM+R++L + NA IV + + Q++P + + I++NPV+ +A
Sbjct: 71 DSDVVVITAGIARKPGMSRNELCDINAGIVTHVVRQVVQHSPNSTLIILSNPVDIMTYVA 130
Query: 510 LK 515
K
Sbjct: 131 FK 132
>UniRef50_A4L2P0 Cluster: L-lactate dehydrogenase; n=4;
Lactobacillus|Rep: L-lactate dehydrogenase -
Lactobacillus reuteri
Length = 312
Score = 62.1 bits (144), Expect = 1e-08
Identities = 36/90 (40%), Positives = 53/90 (58%)
Frame = +3
Query: 252 SDLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIA 431
+D++ + P K+ + G E +A DADVVVI AG+PRKPG TR DL N N +I++ I
Sbjct: 53 ADITPLTNPVKI--YAGTYEDAA---DADVVVITAGIPRKPGETRLDLVNKNTTILKSII 107
Query: 432 LSIAQNAPKAIVAIITNPVNSTVPIALKCS 521
I ++ + I +NPV+ IA + S
Sbjct: 108 KPIVKSGFTGVFVISSNPVDILTTIAQRIS 137
>UniRef50_A0RPE9 Cluster: Malate dehydrogenase; n=1; Campylobacter
fetus subsp. fetus 82-40|Rep: Malate dehydrogenase -
Campylobacter fetus subsp. fetus (strain 82-40)
Length = 306
Score = 62.1 bits (144), Expect = 1e-08
Identities = 29/64 (45%), Positives = 43/64 (67%)
Frame = +3
Query: 324 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 503
+KD D+VVI AG RK G +RDDL NA IV + +++ APK+I+ ++TNP++ V
Sbjct: 67 LKDFDIVVITAGFARKDGQSRDDLAMMNAKIVSHSSKMVSKFAPKSIIIVVTNPLDIMVY 126
Query: 504 IALK 515
+A K
Sbjct: 127 VAFK 130
>UniRef50_Q979N9 Cluster: Malate dehydrogenase; n=4;
Thermoplasmatales|Rep: Malate dehydrogenase -
Thermoplasma volcanium
Length = 325
Score = 61.3 bits (142), Expect = 2e-08
Identities = 22/56 (39%), Positives = 43/56 (76%)
Frame = +3
Query: 324 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 491
++ +DV+V+ AG+ RKPGM+R+DLF+ N I+ D++ +I + +P +I+ +++NP +
Sbjct: 74 MEGSDVIVVTAGMARKPGMSREDLFDKNVEIIADVSKNIKKYSPDSIIVVVSNPAD 129
>UniRef50_UPI0000D571DB Cluster: PREDICTED: similar to CG7998-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG7998-PA - Tribolium castaneum
Length = 376
Score = 60.5 bits (140), Expect = 4e-08
Identities = 29/69 (42%), Positives = 45/69 (65%), Gaps = 1/69 (1%)
Frame = +2
Query: 509 SEVLKKAGVYDPNRVLGVTTLDVSRCHLRRRD-QWRGPNSVAVPVIGGHSGITIIPILSQ 685
SE++KK G Y+P + G+TT+DV R + + P V VP++GGHS TI+P+LSQ
Sbjct: 156 SEIMKKYGHYNPYSIFGITTVDVVRTNKFVAEILGLEPECVTVPIVGGHSEKTIVPVLSQ 215
Query: 686 CQPALKLSD 712
+P +L++
Sbjct: 216 AKPCNELTN 224
Score = 58.8 bits (136), Expect = 1e-07
Identities = 34/123 (27%), Positives = 67/123 (54%), Gaps = 1/123 (0%)
Frame = +3
Query: 252 SDLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIA 431
+DL++++T +V+ G +++ A+ ++++V+ + LF+ NA IV+D+A
Sbjct: 70 NDLNYVDTKCRVTSFFGNKDIQKALTKSNIIVVLSCCHAAEPTNYASLFDRNAPIVKDLA 129
Query: 432 LSIAQNAPKAIVAIITNPVNSTVPIALKCSRR-RECTTRTACSASPLWTYRAATFVGEIN 608
SIA+ +PK+ VAI P+NS VP+ + ++ + + + R FV EI
Sbjct: 130 TSIAKFSPKSTVAIGVEPINSVVPMFSEIMKKYGHYNPYSIFGITTVDVVRTNKFVAEIL 189
Query: 609 GVD 617
G++
Sbjct: 190 GLE 192
>UniRef50_P11386 Cluster: Malate dehydrogenase; n=6;
Sulfolobaceae|Rep: Malate dehydrogenase - Sulfolobus
acidocaldarius
Length = 306
Score = 60.5 bits (140), Expect = 4e-08
Identities = 32/87 (36%), Positives = 47/87 (54%)
Frame = +3
Query: 324 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 503
I AD+VVI AG PRKPGM+R DLF NA I+ D+A + + A+ ++ NPV+
Sbjct: 68 ISGADIVVITAGKPRKPGMSRRDLFIDNAKIMIDLAKKLPKKNKGAMYIMVANPVDMMAS 127
Query: 504 IALKCSRRRECTTRTACSASPLWTYRA 584
+ +K S +T + +Y A
Sbjct: 128 VFMKYSGENTISTGNQVETMRMRSYIA 154
>UniRef50_A2SSY4 Cluster: L-lactate dehydrogenase; n=3;
Methanomicrobiales|Rep: L-lactate dehydrogenase -
Methanocorpusculum labreanum (strain ATCC 43576 / DSM
4855 / Z)
Length = 319
Score = 59.7 bits (138), Expect = 7e-08
Identities = 28/66 (42%), Positives = 44/66 (66%)
Frame = +3
Query: 324 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 503
++ +D++V+ +GVPRK TR DL NA IV+ A + + AP+AI+ ++TNPV+
Sbjct: 71 LRGSDIIVLTSGVPRKATQTRLDLALENARIVKVFAEQVGRMAPEAILLVVTNPVDIMTT 130
Query: 504 IALKCS 521
+ALK S
Sbjct: 131 VALKYS 136
>UniRef50_A0RXX8 Cluster: Malate/L-lactate dehydrogenase; n=1;
Cenarchaeum symbiosum|Rep: Malate/L-lactate
dehydrogenase - Cenarchaeum symbiosum
Length = 302
Score = 58.8 bits (136), Expect = 1e-07
Identities = 31/90 (34%), Positives = 52/90 (57%), Gaps = 1/90 (1%)
Frame = +3
Query: 255 DLSHMNTPAKVSGH-KGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIA 431
D++HM + +G + S ++ +D+VV+ AG RKPGMTR DL NA IV+ +
Sbjct: 43 DINHMLAEQGIDTEVRGSNDYSD-MEGSDIVVVVAGAGRKPGMTRMDLLKINAGIVKGVV 101
Query: 432 LSIAQNAPKAIVAIITNPVNSTVPIALKCS 521
+ ++A +++ +TNP++ IA K S
Sbjct: 102 EKVKEHAKDSMIIPVTNPLDPITYIAYKTS 131
>UniRef50_O26290 Cluster: Malate dehydrogenase; n=2;
Methanobacteriaceae|Rep: Malate dehydrogenase -
Methanobacterium thermoautotrophicum
Length = 325
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/61 (49%), Positives = 39/61 (63%)
Frame = +3
Query: 339 VVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIALKC 518
+VVI AGVPR M RDDL N IV D A IA+ AP +I+ ++TNPV+ +AL+
Sbjct: 75 IVVITAGVPRTADMDRDDLAFKNGRIVADYARQIARFAPDSIILVVTNPVDVMTYVALRY 134
Query: 519 S 521
S
Sbjct: 135 S 135
>UniRef50_Q4Q3J5 Cluster: Malate dehydrogenase, putative; n=5;
Trypanosomatidae|Rep: Malate dehydrogenase, putative -
Leishmania major
Length = 342
Score = 58.4 bits (135), Expect = 2e-07
Identities = 29/71 (40%), Positives = 42/71 (59%), Gaps = 1/71 (1%)
Frame = +2
Query: 503 YCSEVLKKAGVYDPNRVLGVTTLDVSRCH-LRRRDQWRGPNSVAVPVIGGHSGITIIPIL 679
+C+E+LK +G +DP ++ GVTTLDV R L P V VPV+GG G+T P++
Sbjct: 146 FCAELLKASGKFDPRKLFGVTTLDVIRTRKLVAGTLHMNPYDVNVPVVGGCGGVTACPLI 205
Query: 680 SQCQPALKLSD 712
+Q + L D
Sbjct: 206 AQTGLRIPLDD 216
Score = 35.1 bits (77), Expect = 1.8
Identities = 22/85 (25%), Positives = 42/85 (49%), Gaps = 1/85 (1%)
Frame = +3
Query: 252 SDLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVP-RKPGMTRDDLFNTNASIVRDI 428
+DLSH++T KV + A ++DA ++++ G RD A +R +
Sbjct: 61 ADLSHIDTLPKVHYATDEGQWPALLRDAQLILVCFGSSFDLLREDRDIALKAAAPTMRRV 120
Query: 429 ALSIAQNAPKAIVAIITNPVNSTVP 503
++A + VA++++PVN+ P
Sbjct: 121 MAAVASSDTTGNVAVVSSPVNALTP 145
>UniRef50_Q7NHJ3 Cluster: Malate dehydrogenase; n=13; cellular
organisms|Rep: Malate dehydrogenase - Gloeobacter
violaceus
Length = 325
Score = 58.4 bits (135), Expect = 2e-07
Identities = 25/63 (39%), Positives = 42/63 (66%)
Frame = +3
Query: 333 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAL 512
+DV+V+ AG R+PGM+RDDL TN IV ++ ++P+A V ++TNP+++ +A
Sbjct: 77 SDVLVVAAGFARQPGMSRDDLLLTNTRIVFEVTQKAVAHSPEATVVVVTNPLDAMSHVAW 136
Query: 513 KCS 521
+ S
Sbjct: 137 RAS 139
>UniRef50_Q3ZZJ7 Cluster: Malate dehydrogenase; n=5; cellular
organisms|Rep: Malate dehydrogenase - Dehalococcoides
sp. (strain CBDB1)
Length = 307
Score = 58.4 bits (135), Expect = 2e-07
Identities = 33/95 (34%), Positives = 54/95 (56%)
Frame = +3
Query: 333 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAL 512
+++VVI AG+ RKPGMTR++L N I+ D+ + + +P+A + +++NPV++ +A
Sbjct: 70 SEIVVITAGIARKPGMTREELLAINQKIMTDVVSNCLKYSPEATLVVVSNPVDTMTYLAW 129
Query: 513 KCSRRRECTTRTACSASPLWTYRAATFVGEINGVD 617
K S R + L R ATFV GV+
Sbjct: 130 KLSGLPR--KRVVGLSGVLDGGRLATFVARELGVN 162
>UniRef50_Q6A9C3 Cluster: L-lactate dehydrogenase; n=2;
Propionibacterium acnes|Rep: L-lactate dehydrogenase -
Propionibacterium acnes
Length = 319
Score = 58.4 bits (135), Expect = 2e-07
Identities = 41/116 (35%), Positives = 60/116 (51%), Gaps = 6/116 (5%)
Frame = +3
Query: 252 SDLSHMN--TPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRD 425
+DL+H TPA V G G + A D+DVV I AG +KPG TR DL NA+I+R
Sbjct: 53 ADLAHGTQFTPASVMG--GADVHDTA--DSDVVFITAGARQKPGQTRLDLAGVNANILRS 108
Query: 426 IALSIAQNAPKAIVAIITNPVNSTVPIALKCS---RRRECTTRTACSASPL-WTYR 581
+ + + +P A+ ++TNP + +A + + R +T T S L W R
Sbjct: 109 LMPQLVEQSPNALFVLVTNPCDVLTVVAQEATGLPANRVFSTGTMLDTSRLRWLIR 164
>UniRef50_A3EWH3 Cluster: Malate/lactate dehydrogenase; n=1;
Leptospirillum sp. Group II UBA|Rep: Malate/lactate
dehydrogenase - Leptospirillum sp. Group II UBA
Length = 320
Score = 58.0 bits (134), Expect = 2e-07
Identities = 35/95 (36%), Positives = 55/95 (57%), Gaps = 1/95 (1%)
Frame = +3
Query: 324 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 503
I+ + VVV+ AG RKPGM+R+DL + N I+ ++A I ++AP ++V ++TNP++
Sbjct: 72 IEGSSVVVVTAGFSRKPGMSREDLLHKNGDIMIEVAEKIRKHAPDSVVIMVTNPMDLMAY 131
Query: 504 IALKCSR-RRECTTRTACSASPLWTYRAATFVGEI 605
I K + RE R L + R A FV E+
Sbjct: 132 ILWKVTGFPRE---RVIGMGGALDSSRFAYFVSEV 163
>UniRef50_Q892U0 Cluster: L-lactate dehydrogenase; n=12;
Bacteria|Rep: L-lactate dehydrogenase - Clostridium
tetani
Length = 316
Score = 57.6 bits (133), Expect = 3e-07
Identities = 34/97 (35%), Positives = 52/97 (53%)
Frame = +3
Query: 327 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 506
KD+D+V+I AG KPG TR DL N N I + I + + +PK+I+ +++NPV+ +
Sbjct: 71 KDSDIVIITAGAGPKPGETRLDLINKNYEIFKGIVPEVVKYSPKSILLVVSNPVDILTYV 130
Query: 507 ALKCSRRRECTTRTACSASPLWTYRAATFVGEINGVD 617
K S + R S + L T R +GE +D
Sbjct: 131 TYKLSGFPQ--ERVIGSGTVLDTSRFRYLLGEHFKID 165
>UniRef50_UPI00015BB1FC Cluster: malate dehydrogenase (NAD); n=1;
Ignicoccus hospitalis KIN4/I|Rep: malate dehydrogenase
(NAD) - Ignicoccus hospitalis KIN4/I
Length = 311
Score = 57.2 bits (132), Expect = 4e-07
Identities = 35/94 (37%), Positives = 47/94 (50%)
Frame = +3
Query: 324 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 503
+++AD +VI AG PRK M+R DL NA I+RDI + P A +ITNPV+
Sbjct: 72 VENADAIVITAGKPRKADMSRRDLAKVNAQIIRDIGDKLRDRNPGAFYMVITNPVDVMTM 131
Query: 504 IALKCSRRRECTTRTACSASPLWTYRAATFVGEI 605
I + T S L TYR + V E+
Sbjct: 132 ILSDVIGNKGTVIGTGTS---LDTYRFRSAVSEL 162
>UniRef50_Q8XP62 Cluster: L-lactate dehydrogenase; n=11;
Clostridium|Rep: L-lactate dehydrogenase - Clostridium
perfringens
Length = 317
Score = 57.2 bits (132), Expect = 4e-07
Identities = 27/68 (39%), Positives = 41/68 (60%)
Frame = +3
Query: 318 AAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNST 497
A KD+D+V+I AGV KPG TR D+ N N I + I + + +P +I+ +++NPV+
Sbjct: 69 ADTKDSDIVIITAGVGPKPGETRLDIINKNLKIFQSIVPEVVKYSPNSILLVVSNPVDIL 128
Query: 498 VPIALKCS 521
I K S
Sbjct: 129 TYITYKLS 136
>UniRef50_A4BB89 Cluster: Lactate dehydrogenase; n=2;
Gammaproteobacteria|Rep: Lactate dehydrogenase -
Reinekea sp. MED297
Length = 319
Score = 56.8 bits (131), Expect = 5e-07
Identities = 28/54 (51%), Positives = 34/54 (62%)
Frame = +3
Query: 324 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNP 485
+ DAD+VVI AG K G TRDDL N+ I DIA I AP AI+ ++TNP
Sbjct: 68 LTDADIVVITAGAQIKEGQTRDDLAEINSRITVDIAQKIETVAPNAILLVVTNP 121
>UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=1;
Entamoeba histolytica|Rep: NAD-specific malate
dehydrogenase 2 - Entamoeba histolytica
Length = 329
Score = 56.8 bits (131), Expect = 5e-07
Identities = 28/81 (34%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
Frame = +3
Query: 282 KVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKA 461
K+ G E++ A + DV +I AGVPRKPGM R DL N N ++ ++ + K
Sbjct: 71 KLKGIISTTEIALAFSNVDVAIIVAGVPRKPGMQRSDLINVNKKVMEMNGKALGTYSNKD 130
Query: 462 I-VAIITNPVNSTVPIALKCS 521
+ V ++ NP N+ + K S
Sbjct: 131 VRVVVVANPANTNAYVICKTS 151
>UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex
aeolicus|Rep: Malate dehydrogenase 2 - Aquifex aeolicus
Length = 334
Score = 56.8 bits (131), Expect = 5e-07
Identities = 27/83 (32%), Positives = 48/83 (57%)
Frame = +3
Query: 267 MNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQ 446
M+ V G +E +K +D+VVI AG+PR+ GM+R+DL N I++ +I +
Sbjct: 67 MDIDINVKGISYDKEGFEELKGSDIVVITAGIPRREGMSREDLLYENLKILKKFTDAIKE 126
Query: 447 NAPKAIVAIITNPVNSTVPIALK 515
A +I+ +++NPV++ +K
Sbjct: 127 YAKDSIIIVVSNPVDTLTYATIK 149
>UniRef50_A7DRG3 Cluster: Lactate/malate dehydrogenase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
Lactate/malate dehydrogenase - Candidatus Nitrosopumilus
maritimus SCM1
Length = 304
Score = 56.4 bits (130), Expect = 7e-07
Identities = 31/88 (35%), Positives = 49/88 (55%)
Frame = +3
Query: 258 LSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALS 437
LS +V G E++ K +++VV+ AG RKPGMTR DL NASIV+ + +
Sbjct: 48 LSEQGIDVEVKGSNNFEDM----KGSNIVVVVAGSGRKPGMTRMDLLKINASIVKSVVEN 103
Query: 438 IAQNAPKAIVAIITNPVNSTVPIALKCS 521
+ + A +++ +TNP++ I K S
Sbjct: 104 VKKYADDSMIIPVTNPLDPMAYITYKVS 131
>UniRef50_Q7M9A7 Cluster: Malate dehydrogenase; n=4;
Epsilonproteobacteria|Rep: Malate dehydrogenase -
Wolinella succinogenes
Length = 314
Score = 56.4 bits (130), Expect = 7e-07
Identities = 23/64 (35%), Positives = 42/64 (65%)
Frame = +3
Query: 324 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 503
++ DVVV AG PR+PGM+RDDL NA ++R + + ++++ +++NP+++ V
Sbjct: 65 LRGCDVVVFCAGSPRQPGMSRDDLLLANAKVIRTVLSEVKPYIQESVLVMVSNPLDAMVY 124
Query: 504 IALK 515
A+K
Sbjct: 125 TAIK 128
>UniRef50_P62056 Cluster: L-lactate dehydrogenase; n=2;
Bacteria|Rep: L-lactate dehydrogenase - Treponema
denticola
Length = 315
Score = 56.0 bits (129), Expect = 9e-07
Identities = 27/64 (42%), Positives = 40/64 (62%)
Frame = +3
Query: 330 DADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIA 509
D+D+VV+ AG ++ G TR DL NASI+ IA IA++ ++ I++NPV+ A
Sbjct: 72 DSDIVVVTAGAKQQSGETRIDLLKRNASIITGIAKDIAESGCSGVMLIVSNPVDILTRAA 131
Query: 510 LKCS 521
LK S
Sbjct: 132 LKAS 135
>UniRef50_A5Z9B1 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 312
Score = 55.6 bits (128), Expect = 1e-06
Identities = 26/55 (47%), Positives = 36/55 (65%)
Frame = +3
Query: 327 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 491
KDAD++VI AGVPR PG TR D+ + + VRDI ++ + K I+ ITNP +
Sbjct: 71 KDADIIVISAGVPRLPGQTRLDVLDGSVECVRDIVSNLNKIEIKGIIITITNPAD 125
>UniRef50_P0C0J4 Cluster: L-lactate dehydrogenase; n=5; Mycoplasma
hyopneumoniae|Rep: L-lactate dehydrogenase - Mycoplasma
hyopneumoniae
Length = 315
Score = 55.6 bits (128), Expect = 1e-06
Identities = 26/56 (46%), Positives = 37/56 (66%)
Frame = +3
Query: 324 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 491
+KDAD +VI AG P+KPG TR +L N I+R+IAL + ++ I I+ NPV+
Sbjct: 69 LKDADFIVITAGRPQKPGETRLELVADNIRIIREIALKVKESGFSGISIIVANPVD 124
>UniRef50_Q81K80 Cluster: L-lactate dehydrogenase 2; n=12;
Firmicutes|Rep: L-lactate dehydrogenase 2 - Bacillus
anthracis
Length = 314
Score = 55.6 bits (128), Expect = 1e-06
Identities = 35/79 (44%), Positives = 41/79 (51%)
Frame = +3
Query: 255 DLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIAL 434
DLSH P S K A KDAD+VVI AG+P+KPG TR DL N I + I
Sbjct: 49 DLSHA-VPFSPSPTKVWSGSYADCKDADLVVITAGLPQKPGETRLDLVEKNTKIFKQIVR 107
Query: 435 SIAQNAPKAIVAIITNPVN 491
I + I I TNPV+
Sbjct: 108 GIMDSGFDGIFLIATNPVD 126
>UniRef50_A2SNY0 Cluster: Malate/lactate dehydrogenases-like
protein; n=1; Methylibium petroleiphilum PM1|Rep:
Malate/lactate dehydrogenases-like protein - Methylibium
petroleiphilum (strain PM1)
Length = 432
Score = 54.4 bits (125), Expect = 3e-06
Identities = 26/70 (37%), Positives = 42/70 (60%)
Frame = +3
Query: 300 GPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIIT 479
G ++L A+ A+ +VI AG PR+PGM+R DL NA I+ + I +AP + + I++
Sbjct: 183 GSDDL-VALAGAEYIVITAGKPRQPGMSRTDLTVVNAEIMTSVCRGIRTHAPNSTLVIVS 241
Query: 480 NPVNSTVPIA 509
NP+ +A
Sbjct: 242 NPLEEMTHLA 251
>UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;
Candidatus Methanoregula boonei 6A8|Rep: L-lactate
dehydrogenase precursor - Methanoregula boonei (strain
6A8)
Length = 332
Score = 54.4 bits (125), Expect = 3e-06
Identities = 28/66 (42%), Positives = 39/66 (59%)
Frame = +3
Query: 324 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 503
+ +D+VVI AG PR PG R DL NA I+ +A +I AP + ++TNPV+
Sbjct: 71 VAGSDIVVITAGTPRGPGQNRLDLALGNARIIAPMARTIGTIAPDTKIIMVTNPVDVMTC 130
Query: 504 IALKCS 521
+ALK S
Sbjct: 131 VALKYS 136
>UniRef50_UPI0000D55CD8 Cluster: PREDICTED: similar to Malate
DeHydrogenase family member (mdh-1); n=1; Tribolium
castaneum|Rep: PREDICTED: similar to Malate
DeHydrogenase family member (mdh-1) - Tribolium
castaneum
Length = 374
Score = 54.0 bits (124), Expect = 4e-06
Identities = 35/117 (29%), Positives = 60/117 (51%), Gaps = 1/117 (0%)
Frame = +3
Query: 255 DLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIAL 434
DL+ ++T K+ + L AI A VV+ G KPG ++ +LF+ N VR++A+
Sbjct: 72 DLNEIDTRTKLKSFSC-KSLKNAIVGAHVVISTGGCQEKPGSSQRELFDKNLDNVRNVAM 130
Query: 435 SIAQNAPKAIVAIITNPVNSTVPIALKCSRRREC-TTRTACSASPLWTYRAATFVGE 602
+A+ P+AI I PV + VP+ + ++ E R + + + A TF+ E
Sbjct: 131 FLAEFNPEAIYCIAKPPVEALVPMVSEEYKKAETYDPRKIIGVATVASMIANTFIAE 187
Score = 46.4 bits (105), Expect = 7e-04
Identities = 25/64 (39%), Positives = 36/64 (56%), Gaps = 2/64 (3%)
Frame = +2
Query: 509 SEVLKKAGVYDPNRVLGVTTLD--VSRCHLRRRDQWRGPNSVAVPVIGGHSGITIIPILS 682
SE KKA YDP +++GV T+ ++ + + P V P+IGG S T IP+LS
Sbjct: 156 SEEYKKAETYDPRKIIGVATVASMIANTFIAEHTN-QNPADVLCPIIGGLSPKTTIPVLS 214
Query: 683 QCQP 694
Q +P
Sbjct: 215 QTKP 218
>UniRef50_A5KJY5 Cluster: Putative uncharacterized protein; n=2;
Ruminococcus|Rep: Putative uncharacterized protein -
Ruminococcus torques ATCC 27756
Length = 316
Score = 54.0 bits (124), Expect = 4e-06
Identities = 28/64 (43%), Positives = 40/64 (62%)
Frame = +3
Query: 324 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVP 503
I DA VV+I AG +KPG TR DL NA+I+R I I + + I+ I++NPV+
Sbjct: 69 IADASVVIITAGANQKPGETRLDLVQKNAAIMRSIIKEIKRVNCEGILLIVSNPVDILTE 128
Query: 504 IALK 515
+AL+
Sbjct: 129 VALR 132
>UniRef50_Q1FID3 Cluster: L-lactate dehydrogenase precursor; n=1;
Clostridium phytofermentans ISDg|Rep: L-lactate
dehydrogenase precursor - Clostridium phytofermentans
ISDg
Length = 325
Score = 53.6 bits (123), Expect = 5e-06
Identities = 35/100 (35%), Positives = 52/100 (52%), Gaps = 3/100 (3%)
Frame = +3
Query: 327 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 506
KDAD+VVI AG P KPG +R D +A IV I + ++ I ++TNPV+S
Sbjct: 74 KDADIVVITAGPPPKPGQSRLDTLGLSADIVSTIVEPVMKSGFNGIFLVVTNPVDSIAQY 133
Query: 507 ALKCS---RRRECTTRTACSASPLWTYRAATFVGEINGVD 617
+ S +++ T TA ++ R F+G+I VD
Sbjct: 134 VYQLSGLPKQQVLGTGTAIDSA-----RLKHFIGDILHVD 168
>UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2;
Ascomycota|Rep: Probable L-lactate dehydrogenase -
Schizosaccharomyces pombe (Fission yeast)
Length = 330
Score = 53.6 bits (123), Expect = 5e-06
Identities = 34/97 (35%), Positives = 49/97 (50%)
Frame = +3
Query: 327 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 506
KDA VVI AG +KPG TR DL N SI ++I + + AI+ + TNPV+
Sbjct: 86 KDATAVVITAGKNQKPGETRMDLLKANISIFKEILREVTKYTKDAILLVATNPVDVLTYA 145
Query: 507 ALKCSRRRECTTRTACSASPLWTYRAATFVGEINGVD 617
LK + R S + + T R +G++ G+D
Sbjct: 146 TLKLTGFP--AERVIGSGTIIDTARFQYLIGKLYGLD 180
>UniRef50_P50933 Cluster: L-lactate dehydrogenase; n=7;
Bacteria|Rep: L-lactate dehydrogenase - Deinococcus
radiodurans
Length = 304
Score = 53.6 bits (123), Expect = 5e-06
Identities = 28/72 (38%), Positives = 42/72 (58%)
Frame = +3
Query: 294 HKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAI 473
H G EL+ DA VV++ AG +KPG +R DL NA I R++ I + AP A++ +
Sbjct: 59 HGGHSELA----DAQVVILTAGANQKPGESRLDLLEKNADIFRELVPQITRAAPDAVLLV 114
Query: 474 ITNPVNSTVPIA 509
+NPV+ +A
Sbjct: 115 TSNPVDLLTDLA 126
>UniRef50_P59390 Cluster: L-lactate dehydrogenase 2; n=8;
Lactobacillus|Rep: L-lactate dehydrogenase 2 -
Lactobacillus plantarum
Length = 309
Score = 53.6 bits (123), Expect = 5e-06
Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 3/87 (3%)
Frame = +3
Query: 318 AAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNST 497
A +DAD+VVI AGVPRKPG +R DL N N I+ I + + I +NPV+
Sbjct: 68 ADARDADIVVITAGVPRKPGESRLDLINRNTKILESIVKPVVASGFNGCFVISSNPVDIL 127
Query: 498 VPIALKCS---RRRECTTRTACSASPL 569
+ + S R R T T+ + L
Sbjct: 128 TSMTQRLSGFPRHRVIGTGTSLDTARL 154
>UniRef50_Q6KIP9 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
mobile|Rep: L-lactate dehydrogenase - Mycoplasma mobile
Length = 318
Score = 52.8 bits (121), Expect = 8e-06
Identities = 25/56 (44%), Positives = 38/56 (67%)
Frame = +3
Query: 324 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 491
+KD DVVVI AG P+KPG TR ++ NA I+ +IA +I ++ K + ++ NPV+
Sbjct: 71 LKDYDVVVITAGRPQKPGETRLEMVADNAKIMSNIAKNIKKSGFKGVSIVVANPVD 126
>UniRef50_P19869 Cluster: L-lactate dehydrogenase 2; n=17;
Bacteria|Rep: L-lactate dehydrogenase 2 -
Bifidobacterium longum
Length = 320
Score = 52.8 bits (121), Expect = 8e-06
Identities = 26/63 (41%), Positives = 40/63 (63%)
Frame = +3
Query: 327 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 506
+DAD+VVI AG +KPG +R +L +I++ I ++ + AP AI +ITNPV+ +
Sbjct: 75 RDADMVVITAGPRQKPGQSRLELVGATVNILKAIMPNLVKVAPNAIYMLITNPVDIATHV 134
Query: 507 ALK 515
A K
Sbjct: 135 AQK 137
>UniRef50_Q2S4R2 Cluster: L-lactate dehydrogenase; n=1; Salinibacter
ruber DSM 13855|Rep: L-lactate dehydrogenase -
Salinibacter ruber (strain DSM 13855)
Length = 316
Score = 52.4 bits (120), Expect = 1e-05
Identities = 34/101 (33%), Positives = 53/101 (52%), Gaps = 1/101 (0%)
Frame = +3
Query: 318 AAIKDADVVVIPAGVPRK-PGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNS 494
AA+ +A ++V+ AG ++ P TR L NA I R+I + + ++AP AI+ + TNPV+
Sbjct: 67 AALSNAQIIVLSAGASQQSPDETRLGLLQRNAEIFREIIIQLDKHAPNAILVVATNPVDV 126
Query: 495 TVPIALKCSRRRECTTRTACSASPLWTYRAATFVGEINGVD 617
I + S R R + + L T R +G GVD
Sbjct: 127 LTYICQELSSRP--NRRILGTGTLLDTARFRALLGRHYGVD 165
>UniRef50_UPI0000DB76D8 Cluster: PREDICTED: similar to CG7998-PA;
n=2; Apis mellifera|Rep: PREDICTED: similar to CG7998-PA
- Apis mellifera
Length = 333
Score = 52.0 bits (119), Expect = 1e-05
Identities = 27/92 (29%), Positives = 57/92 (61%), Gaps = 1/92 (1%)
Frame = +3
Query: 255 DLSHMNTPAKVSGHKGPEE-LSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIA 431
DL++++T KVS PE+ L ++ A +V+I V + +++ +NA I+ D+
Sbjct: 44 DLNYIDTKCKVSTCNHPEKCLEETLQGAKIVMI---VTDRTSNESNEVLKSNAIILSDLL 100
Query: 432 LSIAQNAPKAIVAIITNPVNSTVPIALKCSRR 527
+I + +P+A++AI+ NP+NS +P+ ++ ++
Sbjct: 101 PNIIKFSPQAMLAIVMNPINSLIPLTMEMYKK 132
Score = 49.2 bits (112), Expect = 1e-04
Identities = 25/67 (37%), Positives = 37/67 (55%), Gaps = 1/67 (1%)
Frame = +2
Query: 512 EVLKKAGVYDPNRVLGVTTLDVSRCHLRRRDQWR-GPNSVAVPVIGGHSGITIIPILSQC 688
E+ KKAG+Y+ NR+ GV + + + D P +PVIGG T IP+ SQ
Sbjct: 128 EMYKKAGIYEYNRIFGVMNFECLKANSFTADLINIEPECTMIPVIGGGCSETCIPLFSQA 187
Query: 689 QPALKLS 709
+P+ K+S
Sbjct: 188 KPSNKIS 194
>UniRef50_UPI000038D9FF Cluster: COG0039: Malate/lactate
dehydrogenases; n=2; Nostoc punctiforme PCC 73102|Rep:
COG0039: Malate/lactate dehydrogenases - Nostoc
punctiforme PCC 73102
Length = 317
Score = 51.6 bits (118), Expect = 2e-05
Identities = 29/71 (40%), Positives = 41/71 (57%), Gaps = 1/71 (1%)
Frame = +3
Query: 324 IKDADVVVI-PAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTV 500
+ D+D+++I AGV K G TR D + NA I+R + + AP +IV II+NPV+
Sbjct: 71 LADSDIIIIVTAGVQPKLGQTRLDTLSDNAEIIRSTIKELDRVAPNSIVIIISNPVDVLT 130
Query: 501 PIALKCSRRRE 533
IA S R E
Sbjct: 131 RIAQATSTRAE 141
>UniRef50_O51114 Cluster: L-lactate dehydrogenase; n=4; Borrelia
burgdorferi group|Rep: L-lactate dehydrogenase -
Borrelia burgdorferi (Lyme disease spirochete)
Length = 316
Score = 51.6 bits (118), Expect = 2e-05
Identities = 24/65 (36%), Positives = 40/65 (61%)
Frame = +3
Query: 330 DADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIA 509
+AD+VVI AG+ +KPG TR DL + N+ I +DI ++ + I + +NPV+ +
Sbjct: 73 NADIVVITAGLNQKPGETRLDLVDKNSKIFKDIITNVVSSGFDGIFVVASNPVDIMTYVT 132
Query: 510 LKCSR 524
+K S+
Sbjct: 133 MKYSK 137
>UniRef50_Q838C9 Cluster: L-lactate dehydrogenase 2; n=9;
Bacilli|Rep: L-lactate dehydrogenase 2 - Enterococcus
faecalis (Streptococcus faecalis)
Length = 317
Score = 51.6 bits (118), Expect = 2e-05
Identities = 26/65 (40%), Positives = 41/65 (63%)
Frame = +3
Query: 327 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 506
+DAD+VVI AG +KPG +R DL + NA I++ I +I ++ I+ I +NPV+ +
Sbjct: 72 QDADIVVITAGANQKPGQSRLDLVSINAEIMKTIVNNIMKSGFDGILVIASNPVDVLTYV 131
Query: 507 ALKCS 521
A + S
Sbjct: 132 AWQAS 136
>UniRef50_A3DCA4 Cluster: L-lactate dehydrogenase precursor; n=2;
Clostridium|Rep: L-lactate dehydrogenase precursor -
Clostridium thermocellum (strain ATCC 27405 / DSM 1237)
Length = 318
Score = 51.2 bits (117), Expect = 3e-05
Identities = 21/56 (37%), Positives = 35/56 (62%)
Frame = +3
Query: 324 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 491
+KD DV+V+ AG RKPG TR DL N I +++ +I + ++ +++NPV+
Sbjct: 72 VKDCDVIVVTAGANRKPGETRLDLAKKNVMIAKEVTQNIMKYYNHGVILVVSNPVD 127
>UniRef50_P0A3M9 Cluster: L-lactate dehydrogenase; n=140;
Bacteria|Rep: L-lactate dehydrogenase - Streptococcus
pneumoniae
Length = 328
Score = 51.2 bits (117), Expect = 3e-05
Identities = 24/54 (44%), Positives = 33/54 (61%)
Frame = +3
Query: 330 DADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 491
DAD+VVI AG P+KPG TR DL N +I + I + ++ K I + NPV+
Sbjct: 76 DADLVVITAGAPQKPGETRLDLVGKNLAINKSIVTQVVESGFKGIFLVAANPVD 129
>UniRef50_Q27743 Cluster: L-lactate dehydrogenase; n=17;
Apicomplexa|Rep: L-lactate dehydrogenase - Plasmodium
falciparum (isolate CDC / Honduras)
Length = 316
Score = 51.2 bits (117), Expect = 3e-05
Identities = 34/93 (36%), Positives = 49/93 (52%), Gaps = 9/93 (9%)
Frame = +3
Query: 255 DLSHMNTPA----KVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMT-----RDDLFNTN 407
D SH N A KVSG ++L+ A DVV++ AG + PG + RDDL N
Sbjct: 47 DTSHTNVMAYSNCKVSGSNTYDDLAGA----DVVIVTAGFTKAPGKSDKEWNRDDLLPLN 102
Query: 408 ASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 506
I+ +I I +N P A + ++TNPV+ V +
Sbjct: 103 NKIMIEIGGHIKKNCPNAFIIVVTNPVDVMVQL 135
>UniRef50_Q98PG4 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
pulmonis|Rep: L-lactate dehydrogenase - Mycoplasma
pulmonis
Length = 315
Score = 51.2 bits (117), Expect = 3e-05
Identities = 35/120 (29%), Positives = 58/120 (48%)
Frame = +3
Query: 255 DLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIAL 434
D+S +G K A K AD++++ AG P+K G TR ++ N+ I++DIAL
Sbjct: 45 DMSDAIALNSTTGSKIRTGTYADAKGADLLIVAAGRPQKQGETRLEMIADNSKIMKDIAL 104
Query: 435 SIAQNAPKAIVAIITNPVNSTVPIALKCSRRRECTTRTACSASPLWTYRAATFVGEINGV 614
I ++ +I+NPV+ + K + + + S + L T R F+ E GV
Sbjct: 105 EIKKSGFNGFTIVISNPVDILATVFQKVTNFPK--EKVMSSGTFLDTSRFRKFLSEKTGV 162
>UniRef50_Q07841 Cluster: Malate dehydrogenase; n=7;
Halobacteriaceae|Rep: Malate dehydrogenase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 304
Score = 50.4 bits (115), Expect = 4e-05
Identities = 25/53 (47%), Positives = 34/53 (64%)
Frame = +3
Query: 333 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 491
+DVVVI AG+PR+PG TR DL NA I+ DI S+ ++ I +NPV+
Sbjct: 72 SDVVVITAGIPRQPGQTRIDLAGDNAPIMEDIQSSLDEHNDDYISLTTSNPVD 124
>UniRef50_A3JXA9 Cluster: L-lactate dehydrogenase; n=1; Sagittula
stellata E-37|Rep: L-lactate dehydrogenase - Sagittula
stellata E-37
Length = 300
Score = 49.6 bits (113), Expect = 8e-05
Identities = 22/56 (39%), Positives = 36/56 (64%)
Frame = +3
Query: 324 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 491
+ ADVV++ GV +KPG +R +L + NA + R + + + AP AI+ I +NPV+
Sbjct: 56 LSGADVVILACGVSQKPGESRLELLSRNAEVFRAVVGDVTRAAPDAILLIASNPVD 111
>UniRef50_A1HSK3 Cluster: Lactate/malate dehydrogenase; n=1;
Thermosinus carboxydivorans Nor1|Rep: Lactate/malate
dehydrogenase - Thermosinus carboxydivorans Nor1
Length = 303
Score = 49.6 bits (113), Expect = 8e-05
Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 3/98 (3%)
Frame = +3
Query: 333 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAL 512
AD+VVI AG+PRK R L + NA+++ D+ +P I+ ++TNP++ +A
Sbjct: 68 ADIVVITAGIPRKADEPRVLLLSRNAALIADLVRQAVHYSPNCIIFMVTNPLDVMTQLAY 127
Query: 513 KCS---RRRECTTRTACSASPLWTYRAATFVGEINGVD 617
+ S R T + +Y A F + +D
Sbjct: 128 QVSGLPANRVIGMGTVLDTARYRSYLAVAFDADARDID 165
>UniRef50_P62051 Cluster: L-lactate dehydrogenase; n=2;
Desulfovibrio vulgaris subsp. vulgaris|Rep: L-lactate
dehydrogenase - Desulfovibrio vulgaris (strain
Hildenborough / ATCC 29579 / NCIMB8303)
Length = 309
Score = 49.2 bits (112), Expect = 1e-04
Identities = 33/95 (34%), Positives = 46/95 (48%)
Frame = +3
Query: 333 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIAL 512
A +VV+ AG + PG +R DL NA I RDI ++ Q A + + TNPV+ +A
Sbjct: 69 ARIVVVTAGAKQMPGQSRLDLVRVNAGITRDILTAVMQYADDPLYIMATNPVDVLTHVAR 128
Query: 513 KCSRRRECTTRTACSASPLWTYRAATFVGEINGVD 617
+ R S + L + R V EI GVD
Sbjct: 129 TVT--GVAPGRVIGSGTVLDSARFRGHVAEILGVD 161
>UniRef50_Q6JH30 Cluster: Lactate dehydrogenase; n=3; Plasmodium
(Plasmodium)|Rep: Lactate dehydrogenase - Plasmodium
vivax
Length = 299
Score = 48.4 bits (110), Expect = 2e-04
Identities = 34/98 (34%), Positives = 49/98 (50%), Gaps = 9/98 (9%)
Frame = +3
Query: 255 DLSHMNTPA----KVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMT-----RDDLFNTN 407
D SH N A KV+G ++L K ADVV++ AG + PG + RDDL N
Sbjct: 40 DTSHSNVMAYSNCKVTGSNSYDDL----KGADVVIVTAGFTKAPGKSDKEWNRDDLLPLN 95
Query: 408 ASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIALKCS 521
I+ +I I P A + ++TNPV+ V + + S
Sbjct: 96 NKIMIEIGGHIKNLCPNAFIIVVTNPVDVMVQLLFEHS 133
>UniRef50_Q03BE6 Cluster: L-lactate dehydrogenase; n=1;
Lactobacillus casei ATCC 334|Rep: L-lactate
dehydrogenase - Lactobacillus casei (strain ATCC 334)
Length = 312
Score = 48.0 bits (109), Expect = 2e-04
Identities = 22/63 (34%), Positives = 37/63 (58%)
Frame = +3
Query: 327 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 506
K AD++VI AG+ +KPG TR L NA I+++I +I + + + +NPV+ +
Sbjct: 70 KYADIIVITAGIAQKPGQTRLQLLAINAKIMKEITHNIMASGFNGFILVASNPVDVLAEL 129
Query: 507 ALK 515
L+
Sbjct: 130 VLQ 132
>UniRef50_P61973 Cluster: Malate dehydrogenase; n=43; Bacteria|Rep:
Malate dehydrogenase - Bdellovibrio bacteriovorus
Length = 335
Score = 48.0 bits (109), Expect = 2e-04
Identities = 26/72 (36%), Positives = 37/72 (51%), Gaps = 1/72 (1%)
Frame = +3
Query: 315 SAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA-PKAIVAIITNPVN 491
+ A KDADV ++ PR PGM R DL N I +I + A P V ++ NP N
Sbjct: 77 AVAFKDADVALLVGARPRGPGMERKDLLTANGQIFTVQGEAIGKYANPNVKVLVVGNPAN 136
Query: 492 STVPIALKCSRR 527
+ IA+K + +
Sbjct: 137 TNAYIAMKSAMK 148
>UniRef50_Q87JV1 Cluster: Lactate dehydrogenase; n=4; Vibrio|Rep:
Lactate dehydrogenase - Vibrio parahaemolyticus
Length = 317
Score = 47.2 bits (107), Expect = 4e-04
Identities = 23/51 (45%), Positives = 33/51 (64%)
Frame = +3
Query: 333 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNP 485
AD+VVI AG + G TR D+ NA I +IA I + APKA++ +++NP
Sbjct: 71 ADIVVITAGAQIQQGQTRLDIAEINAKIGVEIARKIERVAPKAVLIVVSNP 121
>UniRef50_UPI00015B4591 Cluster: PREDICTED: similar to mitochondrial
malate dehydrogenase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to mitochondrial malate dehydrogenase
- Nasonia vitripennis
Length = 299
Score = 46.8 bits (106), Expect = 5e-04
Identities = 21/63 (33%), Positives = 36/63 (57%), Gaps = 1/63 (1%)
Frame = +2
Query: 509 SEVLKKAGVYDPNRVLGVTTLDVSRCHLRRRDQWR-GPNSVAVPVIGGHSGITIIPILSQ 685
SE+ K +G +DPNR+ G L+ R P+ ++VP+ GG +T++P+LS+
Sbjct: 112 SEIYKYSGDWDPNRIFGSAALESMRISAMTATLLDLNPSFISVPIAGGIDSLTVVPLLSR 171
Query: 686 CQP 694
+P
Sbjct: 172 ARP 174
Score = 35.9 bits (79), Expect = 1.0
Identities = 20/85 (23%), Positives = 43/85 (50%), Gaps = 1/85 (1%)
Frame = +3
Query: 255 DLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDL-FNTNASIVRDIA 431
D+ H++T + H + +++ D+V + G + F +++ V+ +A
Sbjct: 27 DMRHIDTSTTIR-HFRKNSILDGLRNTDIVALMDETDFMMGNKGPFMQFVNSSNYVKSVA 85
Query: 432 LSIAQNAPKAIVAIITNPVNSTVPI 506
+ PKA+VA+ T+PV +T+P+
Sbjct: 86 ECMINVCPKALVAVFTHPVTATLPL 110
>UniRef50_Q7UY63 Cluster: L-lactate/malate dehydrogenase; n=2;
Planctomycetaceae|Rep: L-lactate/malate dehydrogenase -
Rhodopirellula baltica
Length = 304
Score = 46.8 bits (106), Expect = 5e-04
Identities = 23/57 (40%), Positives = 37/57 (64%), Gaps = 1/57 (1%)
Frame = +3
Query: 327 KDADVVVIPAGVP-RKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNS 494
KD+DV++ A VP R P TR ++ N I+RD +A+ +P AIV +++NPV++
Sbjct: 67 KDSDVIIFTASVPFRYPNQTRLEMGIDNMPILRDWMPGLAKASPNAIVVMVSNPVDA 123
>UniRef50_Q7MTK2 Cluster: Malate dehydrogenase; n=4;
Bacteroidales|Rep: Malate dehydrogenase - Porphyromonas
gingivalis (Bacteroides gingivalis)
Length = 334
Score = 46.8 bits (106), Expect = 5e-04
Identities = 26/69 (37%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
Frame = +3
Query: 309 ELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKA-IVAIITNP 485
++ A+ DA +V G PRK GMTR+DL NA I + I P V II NP
Sbjct: 67 DIKEALTDAKYIVSSGGAPRKEGMTREDLLKGNAEIAAQLGKDIKSYCPDCKHVIIIFNP 126
Query: 486 VNSTVPIAL 512
+ T + L
Sbjct: 127 ADITGLVTL 135
>UniRef50_Q6F0L9 Cluster: L-lactate dehydrogenase; n=6;
Mollicutes|Rep: L-lactate dehydrogenase - Mesoplasma
florum (Acholeplasma florum)
Length = 317
Score = 46.8 bits (106), Expect = 5e-04
Identities = 22/53 (41%), Positives = 34/53 (64%)
Frame = +3
Query: 327 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNP 485
KDAD++VI AG P++PG TR +L N+ I++ IA +I + + I +NP
Sbjct: 72 KDADLIVITAGRPQRPGETRLELIADNSRIMKGIAEAIKASGFNGVTVIASNP 124
>UniRef50_A0D8T3 Cluster: Malate dehydrogenase; n=2; Paramecium
tetraurelia|Rep: Malate dehydrogenase - Paramecium
tetraurelia
Length = 322
Score = 46.0 bits (104), Expect = 0.001
Identities = 24/70 (34%), Positives = 36/70 (51%), Gaps = 2/70 (2%)
Frame = +3
Query: 321 AIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAI-VAIITNPVNST 497
A KDADV + +PRKPGM R DL N I + + A + V ++ NP N+
Sbjct: 79 AFKDADVAIFLGAMPRKPGMERSDLLQMNREIFIQQGQILNEQAKSTVKVLVVANPSNTN 138
Query: 498 -VPIALKCSR 524
+A +C++
Sbjct: 139 CATLAHQCTK 148
>UniRef50_A6M0Q2 Cluster: L-lactate dehydrogenase; n=1; Clostridium
beijerinckii NCIMB 8052|Rep: L-lactate dehydrogenase -
Clostridium beijerinckii NCIMB 8052
Length = 316
Score = 45.6 bits (103), Expect = 0.001
Identities = 22/54 (40%), Positives = 33/54 (61%)
Frame = +3
Query: 330 DADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 491
DAD+VVI A +P G TR D+ A I+ +I +I ++ I+ +ITNPV+
Sbjct: 73 DADIVVIAAALPYITGQTRLDMLEKAAGIMNNIVPNIMKSGFSGIIVVITNPVD 126
>UniRef50_Q8I8U4 Cluster: Lactate dehydrogenase; n=3;
Eimeriorina|Rep: Lactate dehydrogenase - Eimeria tenella
Length = 331
Score = 45.6 bits (103), Expect = 0.001
Identities = 25/66 (37%), Positives = 38/66 (57%), Gaps = 5/66 (7%)
Frame = +3
Query: 318 AAIKDADVVVIPAGVPRKPG-----MTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITN 482
A+++ ADVV+I AG+ + G +R DL N I+R++ +I Q P A V ITN
Sbjct: 73 ASLEGADVVIITAGITKAAGKSDQEWSRKDLLPVNVKILREVGAAIKQFCPHAFVINITN 132
Query: 483 PVNSTV 500
P++ V
Sbjct: 133 PLDVMV 138
>UniRef50_A1U9V0 Cluster: Lactate/malate dehydrogenase; n=6;
Actinomycetales|Rep: Lactate/malate dehydrogenase -
Mycobacterium sp. (strain KMS)
Length = 329
Score = 45.2 bits (102), Expect = 0.002
Identities = 27/99 (27%), Positives = 51/99 (51%)
Frame = +3
Query: 195 SSGDQAGFIRHSACDPRRRSDLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKP 374
S+G A + +SA DL+H + G ++++ A +VV+ AG + P
Sbjct: 42 SAGTLALYDTNSAKVRAEVLDLNHGSQFVPECRVGGSDDIAVTAGSA-IVVVTAGAKQHP 100
Query: 375 GMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 491
G +R DL N ++ + + + +++P A+V +TNPV+
Sbjct: 101 GQSRLDLAAANVAMAQTLTPQLLEHSPDAVVIFVTNPVD 139
>UniRef50_Q9PHY2 Cluster: Probable malate dehydrogenase; n=12;
Campylobacter|Rep: Probable malate dehydrogenase -
Campylobacter jejuni
Length = 300
Score = 45.2 bits (102), Expect = 0.002
Identities = 21/55 (38%), Positives = 32/55 (58%)
Frame = +3
Query: 327 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 491
K++D+V+ AG RK G +R++L N SI+ D A I + I+TNPV+
Sbjct: 68 KNSDIVLFSAGFARKDGQSREELLQLNTSIMLDCAKKIKDFTEDPLFIILTNPVD 122
>UniRef50_Q4UJ29 Cluster: L-lactate dehydrogenase, putative; n=2;
Theileria|Rep: L-lactate dehydrogenase, putative -
Theileria annulata
Length = 367
Score = 44.8 bits (101), Expect = 0.002
Identities = 20/44 (45%), Positives = 30/44 (68%)
Frame = +3
Query: 384 RDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIALK 515
RDDL N+ I+RD+ +I + AP+A V +ITNP++ V + LK
Sbjct: 143 RDDLVGYNSKIIRDVGENIKKYAPEAFVIVITNPMDVMVHLMLK 186
>UniRef50_UPI0000DB6C4F Cluster: PREDICTED: similar to Malate
DeHydrogenase family member (mdh-1); n=1; Apis
mellifera|Rep: PREDICTED: similar to Malate
DeHydrogenase family member (mdh-1) - Apis mellifera
Length = 221
Score = 44.4 bits (100), Expect = 0.003
Identities = 25/63 (39%), Positives = 36/63 (57%), Gaps = 1/63 (1%)
Frame = +2
Query: 509 SEVLKKAGVYDPNRVLGVTTLDVSRCH-LRRRDQWRGPNSVAVPVIGGHSGITIIPILSQ 685
SE+ K AG +DP+R++G T LD R L P ++VP++GG TI+P+LS
Sbjct: 29 SEIYKLAGWWDPDRIIGSTALDRMRMEALTANLLDLNPAFLSVPLVGGADLNTIVPLLSC 88
Query: 686 CQP 694
P
Sbjct: 89 ATP 91
>UniRef50_UPI0000D56DC5 Cluster: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor; n=1; Tribolium
castaneum|Rep: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor - Tribolium
castaneum
Length = 349
Score = 44.0 bits (99), Expect = 0.004
Identities = 23/93 (24%), Positives = 47/93 (50%)
Frame = +3
Query: 255 DLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIAL 434
D +H +T +V + + +S ++K AD+VV+ M+ L V +A
Sbjct: 64 DFNHFDTRCRVHSYYDMDSVSKSVKCADIVVMLGLNTSTSKMSIPKLVMAEGVRVAKLAE 123
Query: 435 SIAQNAPKAIVAIITNPVNSTVPIALKCSRRRE 533
+ A+ APKA++ + P++ T+PI + ++ +
Sbjct: 124 TCAKYAPKAVIVVAVTPISVTLPIVAEVYKQSD 156
Score = 39.1 bits (87), Expect = 0.11
Identities = 23/63 (36%), Positives = 32/63 (50%), Gaps = 1/63 (1%)
Frame = +2
Query: 509 SEVLKKAGVYDPNRVLGVTTL-DVSRCHLRRRDQWRGPNSVAVPVIGGHSGITIIPILSQ 685
+EV K++ Y P R+LG L +V + Q P V VP++GG IP+ SQ
Sbjct: 149 AEVYKQSDWYHPGRLLGSAALAEVKANAIAGHYQTLDPQMVHVPIVGGPDLDCAIPLFSQ 208
Query: 686 CQP 694
QP
Sbjct: 209 TQP 211
>UniRef50_A2UB98 Cluster: Lactate/malate dehydrogenase precursor;
n=2; Bacteria|Rep: Lactate/malate dehydrogenase
precursor - Bacillus coagulans 36D1
Length = 327
Score = 43.6 bits (98), Expect = 0.005
Identities = 29/94 (30%), Positives = 47/94 (50%), Gaps = 1/94 (1%)
Frame = +3
Query: 231 ACDPRRRSDLSHM-NTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTN 407
A D R + L++M NT K + + I A V+P+ P R L TN
Sbjct: 45 ALDWRHATALTYMPNTSVKAGDYSECADADVIICAAGPSVLPSEKDEMPD--RAGLARTN 102
Query: 408 ASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIA 509
A++VR++ I + +A++ ITNP+++ V IA
Sbjct: 103 AAVVREVMAGITKYTKEAVIIFITNPLDTIVYIA 136
>UniRef50_Q9GPV2 Cluster: Cytosolic malate dehydrogenase; n=4;
Trichomonadida|Rep: Cytosolic malate dehydrogenase -
Tetratrichomonas gallinarum
Length = 314
Score = 43.6 bits (98), Expect = 0.005
Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +3
Query: 285 VSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAI 464
V+G +++ A KD DV + PRK GM R DL N I +++ A K +
Sbjct: 46 VAGIVWTDKIEEAFKDVDVAFLVGSFPRKDGMDRSDLLAKNGGIFTVQGKALSDFAKKDV 105
Query: 465 -VAIITNPVNSTVPIA 509
V ++ NP N+ IA
Sbjct: 106 KVLVVGNPANTNCLIA 121
>UniRef50_Q23CW4 Cluster: Malate dehydrogenase, cytoplasmic,
putative; n=3; Oligohymenophorea|Rep: Malate
dehydrogenase, cytoplasmic, putative - Tetrahymena
thermophila SB210
Length = 365
Score = 43.2 bits (97), Expect = 0.007
Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 1/71 (1%)
Frame = +3
Query: 315 SAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVA-IITNPVN 491
S +D DV V G PRKPGM R DL N +I + ++ A K + ++ NP N
Sbjct: 115 SILFQDVDVAVFIGGFPRKPGMERKDLLTINGNIFKKQGQALDTVAKKTCKSLVVANPAN 174
Query: 492 STVPIALKCSR 524
+ I + ++
Sbjct: 175 TNCLILAETAK 185
>UniRef50_Q9EVR0 Cluster: L-lactate dehydrogenase; n=1; Selenomonas
ruminantium|Rep: L-lactate dehydrogenase - Selenomonas
ruminantium
Length = 318
Score = 43.2 bits (97), Expect = 0.007
Identities = 22/57 (38%), Positives = 35/57 (61%), Gaps = 2/57 (3%)
Frame = +3
Query: 327 KDADVVVIPAGVPRKPGMTRD--DLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 491
KDA+++VI AG +PG T D L TNA I+ + I + +A++ +ITNP++
Sbjct: 72 KDANIIVITAGPSIRPGETPDRLKLAGTNAKIMSSVMGEIVKRTKEAMIIMITNPLD 128
>UniRef50_Q8ELF0 Cluster: L-lactate dehydrogenase; n=5;
Bacillaceae|Rep: L-lactate dehydrogenase -
Oceanobacillus iheyensis
Length = 321
Score = 43.2 bits (97), Expect = 0.007
Identities = 22/55 (40%), Positives = 30/55 (54%)
Frame = +3
Query: 327 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 491
KDAD+V I AG ++ G TR DL N I ++I + + I I TNPV+
Sbjct: 75 KDADIVCICAGANQQSGETRLDLVEKNMKIFKEIVTDVMNSGFNGIFLIATNPVD 129
>UniRef50_Q1IRL5 Cluster: L-lactate dehydrogenase; n=6;
Bacteria|Rep: L-lactate dehydrogenase - Acidobacteria
bacterium (strain Ellin345)
Length = 321
Score = 42.7 bits (96), Expect = 0.009
Identities = 21/58 (36%), Positives = 33/58 (56%)
Frame = +3
Query: 318 AAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 491
A + A V VI AG ++PG TR L + N +I + I + ++ P ++ I TNPV+
Sbjct: 73 ADCRGAAVTVITAGAAQRPGETRLQLLDRNLAIFQQIVPEVVKHNPDGLLLIATNPVD 130
>UniRef50_P20619 Cluster: L-lactate dehydrogenase X; n=14;
Bacillales|Rep: L-lactate dehydrogenase X - Bacillus
psychrosaccharolyticus
Length = 319
Score = 42.7 bits (96), Expect = 0.009
Identities = 22/55 (40%), Positives = 30/55 (54%)
Frame = +3
Query: 327 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 491
K+AD+V I AG +KPG TR DL N I + + + + I I TNPV+
Sbjct: 73 KEADIVCICAGANQKPGETRLDLVEKNLKIFKSLVDQVMASGFDGIFLIATNPVD 127
>UniRef50_Q64YY6 Cluster: Malate dehydrogenase; n=5;
Bacteroidales|Rep: Malate dehydrogenase - Bacteroides
fragilis
Length = 333
Score = 42.3 bits (95), Expect = 0.012
Identities = 24/69 (34%), Positives = 32/69 (46%), Gaps = 1/69 (1%)
Frame = +3
Query: 309 ELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKA-IVAIITNP 485
++ A+ A +V G RK GMTR+DL NA I I Q P V ++ NP
Sbjct: 67 DIKEALSGAKYIVSSGGAARKAGMTREDLLKGNAEIAAQFGKDIRQYCPDVKHVVVVFNP 126
Query: 486 VNSTVPIAL 512
+ T I L
Sbjct: 127 ADITGLIVL 135
>UniRef50_A1W9K7 Cluster: Malate dehydrogenase; n=95; cellular
organisms|Rep: Malate dehydrogenase - Acidovorax sp.
(strain JS42)
Length = 328
Score = 42.3 bits (95), Expect = 0.012
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 1/80 (1%)
Frame = +3
Query: 279 AKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPK 458
A + H P A KD D ++ PR PGM R DL NA I ++ A +
Sbjct: 69 AGIEAHSDP---MTAFKDTDYALLVGARPRGPGMERADLLAANAQIFTAQGKALNAVASR 125
Query: 459 AI-VAIITNPVNSTVPIALK 515
+ V ++ NP N+ IA+K
Sbjct: 126 NVKVLVVGNPANTNAYIAMK 145
>UniRef50_Q81XJ7 Cluster: L-lactate dehydrogenase 3; n=13;
Firmicutes|Rep: L-lactate dehydrogenase 3 - Bacillus
anthracis
Length = 316
Score = 41.9 bits (94), Expect = 0.016
Identities = 27/86 (31%), Positives = 41/86 (47%), Gaps = 3/86 (3%)
Frame = +3
Query: 327 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPI 506
KD D+V+I AG KPG +R D +A I+ + + ++ I + +NPV+
Sbjct: 72 KDMDIVIITAGPAPKPGQSRLDTLGASAKIMESVVGGVMESGFDGIFLLASNPVDIITYQ 131
Query: 507 ALKCS---RRRECTTRTACSASPLWT 575
K S R R T T+ +S L T
Sbjct: 132 VWKLSGLPRNRVIGTGTSLDSSRLRT 157
>UniRef50_A4A2L6 Cluster: L-lactate dehydrogenase; n=4;
Bacteria|Rep: L-lactate dehydrogenase - Blastopirellula
marina DSM 3645
Length = 313
Score = 41.5 bits (93), Expect = 0.021
Identities = 23/58 (39%), Positives = 33/58 (56%), Gaps = 2/58 (3%)
Frame = +3
Query: 324 IKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPK--AIVAIITNPVN 491
I D+DV+ I AG+ RKP +R DL N N + I S+ K AI +++NPV+
Sbjct: 66 IPDSDVICITAGLRRKPDESRLDLINRNVDLFLSILDSVKSAGVKKDAICFVVSNPVD 123
>UniRef50_A2Q223 Cluster: Lactate/malate dehydrogenase, alpha/beta
C-terminal domain containing protein; n=1; Medicago
truncatula|Rep: Lactate/malate dehydrogenase, alpha/beta
C-terminal domain containing protein - Medicago
truncatula (Barrel medic)
Length = 205
Score = 40.7 bits (91), Expect = 0.036
Identities = 15/25 (60%), Positives = 21/25 (84%)
Frame = +2
Query: 617 PNSVAVPVIGGHSGITIIPILSQCQ 691
P V VPV+GGH+G+TI+P+LSQ +
Sbjct: 33 PREVDVPVVGGHAGVTILPLLSQAK 57
>UniRef50_A2E124 Cluster: Malate dehydrogenase; n=6;
Trichomonadidae|Rep: Malate dehydrogenase - Trichomonas
vaginalis G3
Length = 332
Score = 40.7 bits (91), Expect = 0.036
Identities = 28/106 (26%), Positives = 47/106 (44%), Gaps = 1/106 (0%)
Frame = +3
Query: 300 GPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA-PKAIVAII 476
G +L A +D DV + P+KP D F NASI + +++ A P V +I
Sbjct: 69 GTSDLEEAFRDVDVAFLVGSFPKKPSTKLVDYFQRNASIYSEHGRALSDFAKPTVKVLVI 128
Query: 477 TNPVNSTVPIALKCSRRRECTTRTACSASPLWTYRAATFVGEINGV 614
P N+ +A+ + + + C+ + L RA + + GV
Sbjct: 129 GMPTNTNALVAMTAA--VNLSPKNFCAMTRLDHNRAVYSIAQKLGV 172
>UniRef50_A3CTN0 Cluster: Lactate/malate dehydrogenase; n=1;
Methanoculleus marisnigri JR1|Rep: Lactate/malate
dehydrogenase - Methanoculleus marisnigri (strain ATCC
35101 / DSM 1498 / JR1)
Length = 288
Score = 40.3 bits (90), Expect = 0.048
Identities = 20/61 (32%), Positives = 37/61 (60%), Gaps = 1/61 (1%)
Frame = +3
Query: 315 SAAIKDADVVVIPAGVPRKPGM-TRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 491
+AA++DAD+ V AG PR P + TR DL N + + + + + P +++ +TNP++
Sbjct: 59 TAAMRDADIFVFAAGTPRTPDIKTRADLLEANIPVAKRCS-ELLEGFPGVVIS-VTNPMD 116
Query: 492 S 494
+
Sbjct: 117 A 117
>UniRef50_Q0PQR8 Cluster: Malate dehydrogenase NAD-dependent; n=1;
Endoriftia persephone 'Hot96_1+Hot96_2'|Rep: Malate
dehydrogenase NAD-dependent - Endoriftia persephone
'Hot96_1+Hot96_2'
Length = 170
Score = 39.9 bits (89), Expect = 0.063
Identities = 16/38 (42%), Positives = 26/38 (68%)
Frame = +3
Query: 387 DDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTV 500
DDL + N S+ + +A ++ Q+AP A V + TNP++S V
Sbjct: 16 DDLLDINLSVTKKVATAVKQHAPDAFVILTTNPLDSIV 53
>UniRef50_Q9Z6N1 Cluster: Malate dehydrogenase; n=8;
Chlamydiaceae|Rep: Malate dehydrogenase - Chlamydia
pneumoniae (Chlamydophila pneumoniae)
Length = 328
Score = 39.5 bits (88), Expect = 0.083
Identities = 26/74 (35%), Positives = 37/74 (50%), Gaps = 2/74 (2%)
Frame = +3
Query: 312 LSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASI--VRDIALSIAQNAPKAIVAIITNP 485
L+ A D + VPR PGM R DL N I ++ AL+ A A + ++ NP
Sbjct: 76 LNDAFDGIDAAFLIGAVPRGPGMERGDLLKQNGQIFSLQGAALNTAAKR-DAKIFVVGNP 134
Query: 486 VNSTVPIALKCSRR 527
VN+ IA+K + R
Sbjct: 135 VNTNCWIAMKHAPR 148
>UniRef50_Q9P4B6 Cluster: L-lactate dehydrogenase A; n=48; Rhizopus
oryzae|Rep: L-lactate dehydrogenase A - Rhizopus oryzae
(Rhizopus delemar)
Length = 320
Score = 39.5 bits (88), Expect = 0.083
Identities = 19/59 (32%), Positives = 31/59 (52%)
Frame = +3
Query: 333 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIA 509
AD+VVI AG ++ G R L N +++ I + P A++ ++ NPV+ IA
Sbjct: 71 ADIVVITAGAKQREGEPRTKLIERNFRVLQSIIGGMQPIRPDAVILVVANPVDILTHIA 129
>UniRef50_Q7QQW5 Cluster: Malate dehydrogenase; n=2; Giardia
intestinalis|Rep: Malate dehydrogenase - Giardia lamblia
ATCC 50803
Length = 331
Score = 38.7 bits (86), Expect = 0.15
Identities = 22/71 (30%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
Frame = +3
Query: 285 VSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNA-PKA 461
+SG + + A KD D ++ PRK GM R +L + N I + +I ++A P
Sbjct: 66 LSGFTLTSDNAEAFKDVDYCLLFGAFPRKAGMERAELLSKNKGIFQIQGAAINEHAKPTC 125
Query: 462 IVAIITNPVNS 494
+ +I NP N+
Sbjct: 126 RILVIGNPANT 136
>UniRef50_A2QJT7 Cluster: Catalytic activity: precursor; n=1;
Aspergillus niger|Rep: Catalytic activity: precursor -
Aspergillus niger
Length = 307
Score = 38.7 bits (86), Expect = 0.15
Identities = 21/59 (35%), Positives = 31/59 (52%)
Frame = +3
Query: 333 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIA 509
ADVV+I AGV PG T SI++ I + P AI+ ++ NPV++ +A
Sbjct: 70 ADVVIITAGVNYTPGETTLQHLYHKFSILKSILNEMRPFNPNAIILVVANPVDTLTTLA 128
>UniRef50_Q4JY42 Cluster: L-lactate dehydrogenase; n=1;
Corynebacterium jeikeium K411|Rep: L-lactate
dehydrogenase - Corynebacterium jeikeium (strain K411)
Length = 326
Score = 38.7 bits (86), Expect = 0.15
Identities = 20/55 (36%), Positives = 30/55 (54%)
Frame = +3
Query: 327 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 491
+DA +V I AG +KPG TR DL N +I + I + + I + +NPV+
Sbjct: 82 RDAAMVCICAGAAQKPGETRLDLVAKNTAIFKTIVGDVMSHGFNGIFLVASNPVD 136
>UniRef50_UPI00015B5ACF Cluster: PREDICTED: similar to
ENSANGP00000020184; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000020184 - Nasonia
vitripennis
Length = 352
Score = 38.3 bits (85), Expect = 0.19
Identities = 23/76 (30%), Positives = 41/76 (53%), Gaps = 2/76 (2%)
Frame = +2
Query: 512 EVLKKAGVYDPN-RVLGVTTLDVSRCHLRRRDQWR-GPNSVAVPVIGGHSGITIIPILSQ 685
E+ K+AG+++ + R+ GV +L +R + + + P +VPVIGG + +P+ SQ
Sbjct: 164 ELYKRAGLFEASSRIFGVVSLFATRANGLAAETLKIQPELSSVPVIGGGCPRSCVPLFSQ 223
Query: 686 CQPALKLSDRPRSRRS 733
+P + SR S
Sbjct: 224 TRPCADFTPEELSRLS 239
Score = 33.1 bits (72), Expect = 7.2
Identities = 16/43 (37%), Positives = 24/43 (55%)
Frame = +1
Query: 106 STTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAP 234
++++ RN K G+ LAL LKQ+ L+ LA+YD P
Sbjct: 29 TSSNSRNLKVAIVGATGQTGRSLALCLKQSALIDELAVYDSHP 71
>UniRef50_P47698 Cluster: L-lactate dehydrogenase; n=2;
Mycoplasma|Rep: L-lactate dehydrogenase - Mycoplasma
genitalium
Length = 312
Score = 38.3 bits (85), Expect = 0.19
Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 1/57 (1%)
Frame = +3
Query: 324 IKDADVVVIPAGVPRKP-GMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 491
+KD D + I AG P+K G TR L N I++ IA I ++ + I +NPV+
Sbjct: 69 LKDYDFIFISAGRPQKQGGETRLQLLEGNVEIMKSIAKEIKKSGFNGVTLIASNPVD 125
>UniRef50_Q0BVX0 Cluster: 1-acyl-sn-glycerol-3-phosphate
acyltransferase; n=1; Granulibacter bethesdensis
CGDNIH1|Rep: 1-acyl-sn-glycerol-3-phosphate
acyltransferase - Granulobacter bethesdensis (strain
ATCC BAA-1260 / CGDNIH1)
Length = 248
Score = 37.9 bits (84), Expect = 0.25
Identities = 40/141 (28%), Positives = 59/141 (41%), Gaps = 3/141 (2%)
Frame = -1
Query: 565 GDAEHAVRVVHSRLLEHFRAIGTVELTGFVMMATIALGAF*AMDKAMSRTMEALVLNRSS 386
G A + V V+ +LL+ + LTG M+ G ++ +S +MEA LNR
Sbjct: 89 GLASYPVYVLKKQLLKIPVFGPLLPLTG--MIPVDREGGVTSLRNLVSASMEAASLNRQI 146
Query: 385 RVIP-GLRGTPAGMTTTSASLMAADSSSG-PLWPLTL-AGVFMWERSLRRRGSQALCRIK 215
+ P G R P + A S +G P+ P+T +G+F R+ R+ I
Sbjct: 147 VIFPEGTRTDPGVEVPLHPGIYAVASKTGLPIVPVTTNSGLFWGRRAFRKYPGTINVDIH 206
Query: 214 PAWSPEDSASVEGPKAGRYHR 152
P SP A YHR
Sbjct: 207 PPLSPGSRAVTMEALRSLYHR 227
>UniRef50_A7SAG3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 843
Score = 37.1 bits (82), Expect = 0.44
Identities = 19/65 (29%), Positives = 31/65 (47%), Gaps = 1/65 (1%)
Frame = +3
Query: 189 AESSGDQAG-FIRHSACDPRRRSDLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVP 365
A++S Q G F ++ A P+ ++ H P + GH G + S V +P G+P
Sbjct: 729 AQASPSQQGQFFQYQAMPPQMMANPQHPGIPHQPQGHMGAQSPSQVAPPQQFVYLPQGMP 788
Query: 366 RKPGM 380
+ GM
Sbjct: 789 QPGGM 793
>UniRef50_Q0UX88 Cluster: L-lactate dehydrogenase; n=2;
Phaeosphaeria nodorum|Rep: L-lactate dehydrogenase -
Phaeosphaeria nodorum (Septoria nodorum)
Length = 326
Score = 37.1 bits (82), Expect = 0.44
Identities = 20/59 (33%), Positives = 32/59 (54%)
Frame = +3
Query: 333 ADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIA 509
AD+VVI AG +K G +R L N +I+ I S+ + ++ ++ NPV+ V A
Sbjct: 73 ADIVVITAGAKQKTGESRLSLLTRNLNILSSIFDSMKPISAHTVLLLVANPVDILVYFA 131
>UniRef50_A2SR33 Cluster: Lactate/malate dehydrogenase; n=1;
Methanocorpusculum labreanum Z|Rep: Lactate/malate
dehydrogenase - Methanocorpusculum labreanum (strain
ATCC 43576 / DSM 4855 / Z)
Length = 283
Score = 37.1 bits (82), Expect = 0.44
Identities = 22/59 (37%), Positives = 34/59 (57%), Gaps = 1/59 (1%)
Frame = +3
Query: 318 AAIKDADVVVIPAGVPRKPGM-TRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVN 491
A +KDAD + AG R P + TR DLF+ N I ++ + + + K IV +TNP++
Sbjct: 59 ADLKDADYCIFSAGYSRSPNIKTRADLFDKNLPIAKESSELLKGFSGKLIV--VTNPMD 115
>UniRef50_Q97DC6 Cluster: L-lactate dehydrogenase 2; n=1;
Clostridium acetobutylicum|Rep: L-lactate dehydrogenase
2 - Clostridium acetobutylicum
Length = 320
Score = 37.1 bits (82), Expect = 0.44
Identities = 20/56 (35%), Positives = 30/56 (53%), Gaps = 2/56 (3%)
Frame = +3
Query: 330 DADVVVIPAGVPRKPGMTRDDLF--NTNASIVRDIALSIAQNAPKAIVAIITNPVN 491
DA ++VI AG KP D L +TN + I +I + AI+ ++TNPV+
Sbjct: 74 DAQIIVITAGPSLKPDDKLDRLVLADTNVKVTDSIMKNICKYTKDAIIIVVTNPVD 129
>UniRef50_Q017A7 Cluster: Chromosome 06 contig 1, DNA sequence; n=1;
Ostreococcus tauri|Rep: Chromosome 06 contig 1, DNA
sequence - Ostreococcus tauri
Length = 131
Score = 36.3 bits (80), Expect = 0.77
Identities = 23/57 (40%), Positives = 29/57 (50%)
Frame = -1
Query: 349 MTTTSASLMAADSSSGPLWPLTLAGVFMWERSLRRRGSQALCRIKPAWSPEDSASVE 179
M TTS S AA SS+ P +P T A VF E S G L + +PA P+ + E
Sbjct: 1 MITTSQSFSAAPSSASPAYPFTCAAVFTCETSAATPGRIHLHQ-QPARLPDPTRGAE 56
>UniRef50_P59050 Cluster: L-lactate dehydrogenase 1; n=3;
Bifidobacterium longum|Rep: L-lactate dehydrogenase 1 -
Bifidobacterium longum
Length = 316
Score = 35.9 bits (79), Expect = 1.0
Identities = 26/100 (26%), Positives = 44/100 (44%)
Frame = +3
Query: 318 AAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNST 497
A KDAD+VVI G R +V ++ ++ + ++ +++NPV+
Sbjct: 70 ADCKDADIVVITVGRKPPANSNRMAELGFTVGLVGEVVDNVMASGFDGVIVMVSNPVDVM 129
Query: 498 VPIALKCSRRRECTTRTACSASPLWTYRAATFVGEINGVD 617
A K R T+ + + L T R T +GE G+D
Sbjct: 130 AWYAWK--RSGLPRTQVLGTGTALDTSRLKTIIGEETGLD 167
>UniRef50_UPI0000DB7268 Cluster: PREDICTED: similar to L-lactate
dehydrogenase A chain (LDH-A) (LDH muscle subunit)
(LDH-M); n=2; Apis mellifera|Rep: PREDICTED: similar to
L-lactate dehydrogenase A chain (LDH-A) (LDH muscle
subunit) (LDH-M) - Apis mellifera
Length = 348
Score = 35.5 bits (78), Expect = 1.4
Identities = 23/74 (31%), Positives = 36/74 (48%)
Frame = +3
Query: 300 GPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIIT 479
G ++ S A +DA V VI G L N +I +D+ + + AP +I+ I+T
Sbjct: 91 GTKDYSLA-RDATVCVITIGDRSTNEQDPSTLLEQNLNIFKDVIPKVCKYAPNSILLIVT 149
Query: 480 NPVNSTVPIALKCS 521
PV+ A+K S
Sbjct: 150 APVDILSYAAMKLS 163
>UniRef50_A5IYS9 Cluster: L-lactate dehydrogenase; n=2;
Mycoplasma|Rep: L-lactate dehydrogenase - Mycoplasma
agalactiae
Length = 323
Score = 35.1 bits (77), Expect = 1.8
Identities = 23/62 (37%), Positives = 29/62 (46%), Gaps = 1/62 (1%)
Frame = +3
Query: 303 PEELSAAIKDADVVVIPAGVPR-KPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIIT 479
P L KDADVVVI A +P K R L NA +++ A + K IV +
Sbjct: 62 PGTLLEDSKDADVVVITASIPADKTFSDRMALAGANAKLMQSFAKDLDAAGFKGIVVVAA 121
Query: 480 NP 485
NP
Sbjct: 122 NP 123
>UniRef50_Q5B0T8 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 237
Score = 35.1 bits (77), Expect = 1.8
Identities = 21/62 (33%), Positives = 29/62 (46%)
Frame = +3
Query: 336 DVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIALK 515
D+VVI AG G T D N SIVR I + ++ I+ NPV+ +A +
Sbjct: 77 DIVVITAGSKYLYGQTSMDYLYRNTSIVRSIINEMKPFRSDTVLLIVANPVDLMTSLAKE 136
Query: 516 CS 521
S
Sbjct: 137 LS 138
>UniRef50_A5FD47 Cluster: RagB/SusD domain protein precursor; n=1;
Flavobacterium johnsoniae UW101|Rep: RagB/SusD domain
protein precursor - Flavobacterium johnsoniae UW101
Length = 507
Score = 34.7 bits (76), Expect = 2.4
Identities = 20/52 (38%), Positives = 31/52 (59%)
Frame = +3
Query: 246 RRSDLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFN 401
R SD+ MN+ A ++G G ++A+ + V AG+P K +TRD+LFN
Sbjct: 376 RYSDILLMNSEAILAG-AGSTTSASALSSFNEVRARAGLPAKTVLTRDELFN 426
>UniRef50_Q4DTK0 Cluster: Putative uncharacterized protein; n=1;
Trypanosoma cruzi|Rep: Putative uncharacterized protein
- Trypanosoma cruzi
Length = 492
Score = 34.7 bits (76), Expect = 2.4
Identities = 18/67 (26%), Positives = 32/67 (47%)
Frame = +3
Query: 306 EELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNP 485
++LS A+ D D VV G +D+ S ++D+ LSI +N ++ +P
Sbjct: 173 DDLSLAVADCDGVVYVNGPDTSEISNENDIERLFVSSIQDVFLSIKRNGKSVRRVVLISP 232
Query: 486 VNSTVPI 506
+S P+
Sbjct: 233 ASSIFPV 239
>UniRef50_UPI00015537B7 Cluster: PREDICTED: hypothetical protein;
n=1; Mus musculus|Rep: PREDICTED: hypothetical protein -
Mus musculus
Length = 217
Score = 34.3 bits (75), Expect = 3.1
Identities = 32/112 (28%), Positives = 48/112 (42%)
Frame = -1
Query: 376 PGLRGTPAGMTTTSASLMAADSSSGPLWPLTLAGVFMWERSLRRRGSQALCRIKPAWSPE 197
PGLRG G++ +A+ GP + + G R GS+ ++P W+
Sbjct: 63 PGLRGPGTGISRPAAAAEGGGLERGPALVIRVPG-----PGGGRAGSER--EVRPPWN-L 114
Query: 196 DSASVEGPKAGRYHRRHQRPPL*SSSVMWWKSSLHHFVQQGRQVLGRGRTFS 41
D A + G + RR P L + WW S+ G QV GRG++ S
Sbjct: 115 DIARGKPRAGGLWRRRVAGPALVAGPGAWW--SVGGVALGGCQVGGRGKSGS 164
>UniRef50_UPI000023E362 Cluster: hypothetical protein FG01393.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG01393.1 - Gibberella zeae PH-1
Length = 703
Score = 34.3 bits (75), Expect = 3.1
Identities = 24/94 (25%), Positives = 38/94 (40%), Gaps = 2/94 (2%)
Frame = +3
Query: 276 PAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAP 455
PA + G + + + A ++ A P+K TR +T A+ + A S + P
Sbjct: 192 PAAPAATNGKPKANTVKELAPAAIVKAATPKKTTTTRPSAVSTKATSTKPPAKSSSATKP 251
Query: 456 KAIVA--IITNPVNSTVPIALKCSRRRECTTRTA 551
+ T P T P A K R+ T+ TA
Sbjct: 252 PSSTTHKAETKPTAKTAPAAKKEHRQASATSSTA 285
>UniRef50_O52354 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
gallisepticum|Rep: L-lactate dehydrogenase - Mycoplasma
gallisepticum
Length = 323
Score = 34.3 bits (75), Expect = 3.1
Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 6/60 (10%)
Frame = +3
Query: 324 IKDADVVVIPAGVPRKPG------MTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNP 485
+KDADVV I A +P P R L N I+ +IAL + + K + I TNP
Sbjct: 68 LKDADVVAITASIPTVPTADGEVFTDRLQLMTANVKILNEIALELKRVGFKGLSIIPTNP 127
>UniRef50_O26630 Cluster: UDP-N-acetylmuramyl tripeptide synthetase
related protein; n=1; Methanothermobacter
thermautotrophicus str. Delta H|Rep: UDP-N-acetylmuramyl
tripeptide synthetase related protein - Methanobacterium
thermoautotrophicum
Length = 682
Score = 33.9 bits (74), Expect = 4.1
Identities = 20/40 (50%), Positives = 25/40 (62%)
Frame = +3
Query: 237 DPRRRSDLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPA 356
D R + L +NT A SG G E++A +KDAD VVIPA
Sbjct: 574 DLRGKGRLIVVNTVASESGIDGDREIAAILKDAD-VVIPA 612
>UniRef50_Q3MGZ6 Cluster: Putative uncharacterized protein
precursor; n=1; Anabaena variabilis ATCC 29413|Rep:
Putative uncharacterized protein precursor - Anabaena
variabilis (strain ATCC 29413 / PCC 7937)
Length = 303
Score = 33.5 bits (73), Expect = 5.5
Identities = 18/51 (35%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Frame = +3
Query: 345 VIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAI-ITNPVNS 494
++P G P KP T D+ +T ++ + L +NA KAI+ + NPVN+
Sbjct: 116 LVPEG-PSKPNPTAQDIVSTLGNLNLNSILVTRENADKAIIEVSFANPVNT 165
>UniRef50_Q7UX97 Cluster: Arylsulfatase B [Precursor]; n=1;
Pirellula sp.|Rep: Arylsulfatase B [Precursor] -
Rhodopirellula baltica
Length = 579
Score = 33.1 bits (72), Expect = 7.2
Identities = 17/57 (29%), Positives = 28/57 (49%), Gaps = 2/57 (3%)
Frame = +2
Query: 545 NRVLGVTTLDVSRCHLRRRDQWRGPNSVAVPVIGGHSGIT--IIPILSQCQPALKLS 709
NR+ + L SRC++ + WR N + V+G G+ I + S C LK++
Sbjct: 53 NRLGAIKKLATSRCYIAGQRNWRRANGICFGVVGDGIGMVDRIRSVFSHCACDLKMA 109
>UniRef50_A2SGX5 Cluster: Putative uncharacterized protein; n=1;
Methylibium petroleiphilum PM1|Rep: Putative
uncharacterized protein - Methylibium petroleiphilum
(strain PM1)
Length = 208
Score = 33.1 bits (72), Expect = 7.2
Identities = 21/66 (31%), Positives = 31/66 (46%)
Frame = +3
Query: 162 RPAFGPSTEAESSGDQAGFIRHSACDPRRRSDLSHMNTPAKVSGHKGPEELSAAIKDADV 341
+PA + AES+G R DP R+ TP V+ KG E+++A+ +
Sbjct: 54 QPAISRALFAESAGAALTLARLPGTDPNARNTAGE--TPLMVAALKGQPEVASALIERGA 111
Query: 342 VVIPAG 359
VV P G
Sbjct: 112 VVDPPG 117
>UniRef50_Q8IE66 Cluster: Oxidoreductase, putative; n=6;
Plasmodium|Rep: Oxidoreductase, putative - Plasmodium
falciparum (isolate 3D7)
Length = 334
Score = 33.1 bits (72), Expect = 7.2
Identities = 17/62 (27%), Positives = 36/62 (58%), Gaps = 6/62 (9%)
Frame = +3
Query: 324 IKDADVVVIPAGVPRKPGMTRDD------LFNTNASIVRDIALSIAQNAPKAIVAIITNP 485
IKD+ VVV+ V + D+ ++ +N +++++A S+ ++ P+A V + T+P
Sbjct: 72 IKDSLVVVVTIEVSEREFAEFDEEDLEKQVYTSNVKLLKEVAKSLKKHCPQAFVVVTTSP 131
Query: 486 VN 491
V+
Sbjct: 132 VD 133
>UniRef50_Q5QU95 Cluster: Uncharacterized conserved secreted
protein; n=1; Idiomarina loihiensis|Rep: Uncharacterized
conserved secreted protein - Idiomarina loihiensis
Length = 771
Score = 32.7 bits (71), Expect = 9.5
Identities = 14/36 (38%), Positives = 22/36 (61%)
Frame = +3
Query: 180 STEAESSGDQAGFIRHSACDPRRRSDLSHMNTPAKV 287
+TEA+S G++ + DP RR+ +SH+ P KV
Sbjct: 586 NTEAKSKGNKHKRVMRENADPNRRNVVSHLKMPKKV 621
>UniRef50_A6S058 Cluster: Mitochondrial ribosome small subunit
component S19; n=2; Sclerotiniaceae|Rep: Mitochondrial
ribosome small subunit component S19 - Botryotinia
fuckeliana B05.10
Length = 93
Score = 32.7 bits (71), Expect = 9.5
Identities = 13/36 (36%), Positives = 21/36 (58%)
Frame = +2
Query: 590 LRRRDQWRGPNSVAVPVIGGHSGITIIPILSQCQPA 697
L R W+GPN V +P++ G+ +PI +Q + A
Sbjct: 7 LLSRSVWKGPNIVPLPIVKPVPGVRTLPIRTQARSA 42
>UniRef50_P15719 Cluster: Malate dehydrogenase [NADP], chloroplast
precursor; n=62; cellular organisms|Rep: Malate
dehydrogenase [NADP], chloroplast precursor - Zea mays
(Maize)
Length = 432
Score = 32.7 bits (71), Expect = 9.5
Identities = 20/64 (31%), Positives = 30/64 (46%), Gaps = 1/64 (1%)
Frame = +3
Query: 327 KDADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSI-AQNAPKAIVAIITNPVNSTVP 503
+D D ++ PR PGM R L + N I D ++ A + V ++ NP N+
Sbjct: 164 QDVDWALLIGAKPRGPGMERAALLDINGQIFADQGKALNAVASRNDEVLVVGNPCNTNAL 223
Query: 504 IALK 515
I LK
Sbjct: 224 ICLK 227
>UniRef50_Q8NHM5 Cluster: JmjC domain-containing histone
demethylation protein 1B; n=56; Euteleostomi|Rep: JmjC
domain-containing histone demethylation protein 1B -
Homo sapiens (Human)
Length = 1336
Score = 32.7 bits (71), Expect = 9.5
Identities = 14/22 (63%), Positives = 16/22 (72%)
Frame = -1
Query: 142 RPPL*SSSVMWWKSSLHHFVQQ 77
RPPL SS WW+SSL +F QQ
Sbjct: 834 RPPLGSSLSPWWRSSLTYFQQQ 855
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 765,141,242
Number of Sequences: 1657284
Number of extensions: 17098973
Number of successful extensions: 54898
Number of sequences better than 10.0: 151
Number of HSP's better than 10.0 without gapping: 51521
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 54830
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 59265488880
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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