Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= NV021141
(733 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
DQ402957-1|ABD77290.1| 305|Homo sapiens mitochondrial malate de... 128 2e-29
CR536548-1|CAG38785.1| 338|Homo sapiens MDH2 protein. 128 2e-29
BC001917-1|AAH01917.1| 338|Homo sapiens malate dehydrogenase 2,... 128 2e-29
AF047470-1|AAC03787.1| 338|Homo sapiens malate dehydrogenase pr... 128 2e-29
AC005077-1|AAS07425.1| 316|Homo sapiens unknown protein. 128 2e-29
BC014340-1|AAH14340.1| 234|Homo sapiens LDHAL6A protein protein. 46 1e-04
AY581313-1|AAS93432.1| 332|Homo sapiens lactate dehydrogenase p... 46 1e-04
AK131523-1|BAD18662.1| 332|Homo sapiens protein ( Homo sapiens ... 46 1e-04
BC008735-1|AAH08735.2| 627|Homo sapiens FBXL10 protein protein. 33 1.4
AK027692-1|BAB55301.1| 653|Homo sapiens protein ( Homo sapiens ... 33 1.4
AK027440-1|BAB55112.1| 704|Homo sapiens protein ( Homo sapiens ... 33 1.4
AJ459424-1|CAD30700.1| 1336|Homo sapiens JEMMA protein protein. 33 1.4
AB031230-1|BAA97672.1| 827|Homo sapiens protein containing CXXC... 33 1.4
BC071674-1|AAH71674.1| 152|Homo sapiens RPS16 protein protein. 30 9.8
>DQ402957-1|ABD77290.1| 305|Homo sapiens mitochondrial malate
dehydrogenase 2, NAD protein.
Length = 305
Score = 128 bits (309), Expect = 2e-29
Identities = 63/127 (49%), Positives = 83/127 (65%), Gaps = 1/127 (0%)
Frame = +3
Query: 240 PRRRSDLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIV 419
P +DLSH+ T A V G+ GPE+L +K DVVVIPAGVPRKPGMTRDDLFNTNA+IV
Sbjct: 41 PGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIV 100
Query: 420 RDIALSIAQNAPKAIVAIITNPVNSTVPIALKCSRRREC-TTRTACSASPLWTYRAATFV 596
+ + AQ+ P+A++ +I NPVNST+PI + ++ + L RA TFV
Sbjct: 101 ATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFV 160
Query: 597 GEINGVD 617
E+ G+D
Sbjct: 161 AELKGLD 167
Score = 71.3 bits (167), Expect = 3e-12
Identities = 34/63 (53%), Positives = 45/63 (71%), Gaps = 1/63 (1%)
Frame = +2
Query: 509 SEVLKKAGVYDPNRVLGVTTLDVSRCHLRRRD-QWRGPNSVAVPVIGGHSGITIIPILSQ 685
+EV KK GVY+PN++ GVTTLD+ R + + + P V VPVIGGH+G TIIP++SQ
Sbjct: 131 AEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQ 190
Query: 686 CQP 694
C P
Sbjct: 191 CTP 193
Score = 51.2 bits (117), Expect = 4e-06
Identities = 28/46 (60%), Positives = 31/46 (67%)
Frame = +1
Query: 118 QRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAA 255
Q N K IGQPL+LLLK +PLV+RL LYDIA TPGVAA
Sbjct: 1 QNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAH-TPGVAA 45
>CR536548-1|CAG38785.1| 338|Homo sapiens MDH2 protein.
Length = 338
Score = 128 bits (309), Expect = 2e-29
Identities = 63/127 (49%), Positives = 83/127 (65%), Gaps = 1/127 (0%)
Frame = +3
Query: 240 PRRRSDLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIV 419
P +DLSH+ T A V G+ GPE+L +K DVVVIPAGVPRKPGMTRDDLFNTNA+IV
Sbjct: 62 PGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIV 121
Query: 420 RDIALSIAQNAPKAIVAIITNPVNSTVPIALKCSRRREC-TTRTACSASPLWTYRAATFV 596
+ + AQ+ P+A++ +I NPVNST+PI + ++ + L RA TFV
Sbjct: 122 ATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFV 181
Query: 597 GEINGVD 617
E+ G+D
Sbjct: 182 AELKGLD 188
Score = 71.3 bits (167), Expect = 3e-12
Identities = 34/63 (53%), Positives = 45/63 (71%), Gaps = 1/63 (1%)
Frame = +2
Query: 509 SEVLKKAGVYDPNRVLGVTTLDVSRCHLRRRD-QWRGPNSVAVPVIGGHSGITIIPILSQ 685
+EV KK GVY+PN++ GVTTLD+ R + + + P V VPVIGGH+G TIIP++SQ
Sbjct: 152 AEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQ 211
Query: 686 CQP 694
C P
Sbjct: 212 CTP 214
Score = 62.5 bits (145), Expect = 2e-09
Identities = 35/70 (50%), Positives = 47/70 (67%)
Frame = +1
Query: 46 MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYD 225
M S ++P + A++ ++FST++Q N K IGQPL+LLLK +PLV+RL LYD
Sbjct: 1 MLSALVRPVSAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYD 57
Query: 226 IAPVTPGVAA 255
IA TPGVAA
Sbjct: 58 IAH-TPGVAA 66
>BC001917-1|AAH01917.1| 338|Homo sapiens malate dehydrogenase 2,
NAD (mitochondrial) protein.
Length = 338
Score = 128 bits (309), Expect = 2e-29
Identities = 63/127 (49%), Positives = 83/127 (65%), Gaps = 1/127 (0%)
Frame = +3
Query: 240 PRRRSDLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIV 419
P +DLSH+ T A V G+ GPE+L +K DVVVIPAGVPRKPGMTRDDLFNTNA+IV
Sbjct: 62 PGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIV 121
Query: 420 RDIALSIAQNAPKAIVAIITNPVNSTVPIALKCSRRREC-TTRTACSASPLWTYRAATFV 596
+ + AQ+ P+A++ +I NPVNST+PI + ++ + L RA TFV
Sbjct: 122 ATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFV 181
Query: 597 GEINGVD 617
E+ G+D
Sbjct: 182 AELKGLD 188
Score = 71.3 bits (167), Expect = 3e-12
Identities = 34/63 (53%), Positives = 45/63 (71%), Gaps = 1/63 (1%)
Frame = +2
Query: 509 SEVLKKAGVYDPNRVLGVTTLDVSRCHLRRRD-QWRGPNSVAVPVIGGHSGITIIPILSQ 685
+EV KK GVY+PN++ GVTTLD+ R + + + P V VPVIGGH+G TIIP++SQ
Sbjct: 152 AEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQ 211
Query: 686 CQP 694
C P
Sbjct: 212 CTP 214
Score = 61.7 bits (143), Expect = 3e-09
Identities = 35/70 (50%), Positives = 46/70 (65%)
Frame = +1
Query: 46 MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYD 225
M S +P + A++ ++FST++Q N K IGQPL+LLLK +PLV+RL LYD
Sbjct: 1 MLSALARPVSAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYD 57
Query: 226 IAPVTPGVAA 255
IA TPGVAA
Sbjct: 58 IAH-TPGVAA 66
>AF047470-1|AAC03787.1| 338|Homo sapiens malate dehydrogenase
precursor protein.
Length = 338
Score = 128 bits (309), Expect = 2e-29
Identities = 63/127 (49%), Positives = 83/127 (65%), Gaps = 1/127 (0%)
Frame = +3
Query: 240 PRRRSDLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIV 419
P +DLSH+ T A V G+ GPE+L +K DVVVIPAGVPRKPGMTRDDLFNTNA+IV
Sbjct: 62 PGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIV 121
Query: 420 RDIALSIAQNAPKAIVAIITNPVNSTVPIALKCSRRREC-TTRTACSASPLWTYRAATFV 596
+ + AQ+ P+A++ +I NPVNST+PI + ++ + L RA TFV
Sbjct: 122 ATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFV 181
Query: 597 GEINGVD 617
E+ G+D
Sbjct: 182 AELKGLD 188
Score = 71.3 bits (167), Expect = 3e-12
Identities = 34/63 (53%), Positives = 45/63 (71%), Gaps = 1/63 (1%)
Frame = +2
Query: 509 SEVLKKAGVYDPNRVLGVTTLDVSRCHLRRRD-QWRGPNSVAVPVIGGHSGITIIPILSQ 685
+EV KK GVY+PN++ GVTTLD+ R + + + P V VPVIGGH+G TIIP++SQ
Sbjct: 152 AEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQ 211
Query: 686 CQP 694
C P
Sbjct: 212 CTP 214
Score = 61.7 bits (143), Expect = 3e-09
Identities = 35/70 (50%), Positives = 46/70 (65%)
Frame = +1
Query: 46 MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYD 225
M S +P + A++ ++FST++Q N K IGQPL+LLLK +PLV+RL LYD
Sbjct: 1 MLSALARPVSAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYD 57
Query: 226 IAPVTPGVAA 255
IA TPGVAA
Sbjct: 58 IAH-TPGVAA 66
>AC005077-1|AAS07425.1| 316|Homo sapiens unknown protein.
Length = 316
Score = 128 bits (309), Expect = 2e-29
Identities = 63/127 (49%), Positives = 83/127 (65%), Gaps = 1/127 (0%)
Frame = +3
Query: 240 PRRRSDLSHMNTPAKVSGHKGPEELSAAIKDADVVVIPAGVPRKPGMTRDDLFNTNASIV 419
P +DLSH+ T A V G+ GPE+L +K DVVVIPAGVPRKPGMTRDDLFNTNA+IV
Sbjct: 40 PGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIV 99
Query: 420 RDIALSIAQNAPKAIVAIITNPVNSTVPIALKCSRRREC-TTRTACSASPLWTYRAATFV 596
+ + AQ+ P+A++ +I NPVNST+PI + ++ + L RA TFV
Sbjct: 100 ATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFV 159
Query: 597 GEINGVD 617
E+ G+D
Sbjct: 160 AELKGLD 166
Score = 71.3 bits (167), Expect = 3e-12
Identities = 34/63 (53%), Positives = 45/63 (71%), Gaps = 1/63 (1%)
Frame = +2
Query: 509 SEVLKKAGVYDPNRVLGVTTLDVSRCHLRRRD-QWRGPNSVAVPVIGGHSGITIIPILSQ 685
+EV KK GVY+PN++ GVTTLD+ R + + + P V VPVIGGH+G TIIP++SQ
Sbjct: 130 AEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQ 189
Query: 686 CQP 694
C P
Sbjct: 190 CTP 192
Score = 49.2 bits (112), Expect = 2e-05
Identities = 25/32 (78%), Positives = 28/32 (87%)
Frame = +1
Query: 160 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAA 255
IGQPL+LLLK +PLV+RL LYDIA TPGVAA
Sbjct: 14 IGQPLSLLLKNSPLVSRLTLYDIAH-TPGVAA 44
>BC014340-1|AAH14340.1| 234|Homo sapiens LDHAL6A protein protein.
Length = 234
Score = 46.0 bits (104), Expect = 1e-04
Identities = 31/95 (32%), Positives = 50/95 (52%)
Frame = +3
Query: 330 DADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIA 509
++++V+I AG +K G TR DL N SI + + +I Q +P + I+TNPV+ +A
Sbjct: 88 NSNLVIITAGARQKKGETRLDLVQRNVSIFKLMIPNITQYSPHCKLLIVTNPVDILTYVA 147
Query: 510 LKCSRRRECTTRTACSASPLWTYRAATFVGEINGV 614
K S + R S L + R F+G+ G+
Sbjct: 148 WKLSGFPK--NRVIGSGCNLDSARFRYFIGQRLGI 180
>AY581313-1|AAS93432.1| 332|Homo sapiens lactate dehydrogenase
protein.
Length = 332
Score = 46.0 bits (104), Expect = 1e-04
Identities = 31/95 (32%), Positives = 50/95 (52%)
Frame = +3
Query: 330 DADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIA 509
++++V+I AG +K G TR DL N SI + + +I Q +P + I+TNPV+ +A
Sbjct: 88 NSNLVIITAGARQKKGETRLDLVQRNVSIFKLMIPNITQYSPHCKLLIVTNPVDILTYVA 147
Query: 510 LKCSRRRECTTRTACSASPLWTYRAATFVGEINGV 614
K S + R S L + R F+G+ G+
Sbjct: 148 WKLSGFPK--NRVIGSGCNLDSARFRYFIGQRLGI 180
>AK131523-1|BAD18662.1| 332|Homo sapiens protein ( Homo sapiens
cDNA FLJ43406 fis, clone OCBBF2019823, highly similar
to Homo sapiens lactate dehydrogenase A -like (LDHL). ).
Length = 332
Score = 46.0 bits (104), Expect = 1e-04
Identities = 31/95 (32%), Positives = 50/95 (52%)
Frame = +3
Query: 330 DADVVVIPAGVPRKPGMTRDDLFNTNASIVRDIALSIAQNAPKAIVAIITNPVNSTVPIA 509
++++V+I AG +K G TR DL N SI + + +I Q +P + I+TNPV+ +A
Sbjct: 88 NSNLVIITAGARQKKGETRLDLVQRNVSIFKLMIPNITQYSPHCKLLIVTNPVDILTYVA 147
Query: 510 LKCSRRRECTTRTACSASPLWTYRAATFVGEINGV 614
K S + R S L + R F+G+ G+
Sbjct: 148 WKLSGFPK--NRVIGSGCNLDSARFRYFIGQRLGI 180
>BC008735-1|AAH08735.2| 627|Homo sapiens FBXL10 protein protein.
Length = 627
Score = 32.7 bits (71), Expect = 1.4
Identities = 14/22 (63%), Positives = 16/22 (72%)
Frame = -1
Query: 142 RPPL*SSSVMWWKSSLHHFVQQ 77
RPPL SS WW+SSL +F QQ
Sbjct: 125 RPPLGSSLSPWWRSSLTYFQQQ 146
>AK027692-1|BAB55301.1| 653|Homo sapiens protein ( Homo sapiens
cDNA FLJ14786 fis, clone NT2RP4000737, moderately
similar to Mus musculus F-box protein FBL10 mRNA. ).
Length = 653
Score = 32.7 bits (71), Expect = 1.4
Identities = 14/22 (63%), Positives = 16/22 (72%)
Frame = -1
Query: 142 RPPL*SSSVMWWKSSLHHFVQQ 77
RPPL SS WW+SSL +F QQ
Sbjct: 151 RPPLGSSLSPWWRSSLTYFQQQ 172
>AK027440-1|BAB55112.1| 704|Homo sapiens protein ( Homo sapiens
cDNA FLJ14534 fis, clone NT2RM2000599, weakly similar to
Homo sapiens F-box protein Lilina (LILINA) mRNA. ).
Length = 704
Score = 32.7 bits (71), Expect = 1.4
Identities = 14/22 (63%), Positives = 16/22 (72%)
Frame = -1
Query: 142 RPPL*SSSVMWWKSSLHHFVQQ 77
RPPL SS WW+SSL +F QQ
Sbjct: 202 RPPLGSSLSPWWRSSLTYFQQQ 223
>AJ459424-1|CAD30700.1| 1336|Homo sapiens JEMMA protein protein.
Length = 1336
Score = 32.7 bits (71), Expect = 1.4
Identities = 14/22 (63%), Positives = 16/22 (72%)
Frame = -1
Query: 142 RPPL*SSSVMWWKSSLHHFVQQ 77
RPPL SS WW+SSL +F QQ
Sbjct: 834 RPPLGSSLSPWWRSSLTYFQQQ 855
>AB031230-1|BAA97672.1| 827|Homo sapiens protein containing CXXC
domain 2 protein.
Length = 827
Score = 32.7 bits (71), Expect = 1.4
Identities = 14/22 (63%), Positives = 16/22 (72%)
Frame = -1
Query: 142 RPPL*SSSVMWWKSSLHHFVQQ 77
RPPL SS WW+SSL +F QQ
Sbjct: 358 RPPLGSSLSPWWRSSLTYFQQQ 379
>BC071674-1|AAH71674.1| 152|Homo sapiens RPS16 protein protein.
Length = 152
Score = 29.9 bits (64), Expect = 9.8
Identities = 18/57 (31%), Positives = 23/57 (40%), Gaps = 1/57 (1%)
Frame = -1
Query: 373 GLRGTPAGMTTTSASLMAADSSSGPLWPLTLAGVFMWERSLRRRGSQALCRIK-PAW 206
GL P S S ++ S P WP+T MW R RRR + + P W
Sbjct: 99 GLHSAPVPFNCVSFSQLSVSPSPKPWWPITRN---MWMRLPRRRSKTSSSSMTGPCW 152
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 113,332,135
Number of Sequences: 237096
Number of extensions: 2780139
Number of successful extensions: 7308
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 6732
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7298
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8679165170
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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