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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= NV021023
         (623 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

U36268-1|AAC50684.2|  949|Homo sapiens beta-prime-adaptin protein.    148   2e-35
L13939-1|AAC98702.1|  949|Homo sapiens beta-prime-adaptin protein.    148   2e-35
CT841508-1|CAJ86438.1|  939|Homo sapiens AP1B1 protein.               148   2e-35
BC046242-1|AAH46242.1|  919|Homo sapiens AP1B1 protein protein.       148   2e-35
M34175-1|AAA35583.1|  937|Homo sapiens protein ( Human beta adap...   137   3e-32
BC006201-1|AAH06201.1|  951|Homo sapiens adaptor-related protein...   137   3e-32
AY341427-1|AAQ20044.1|  880|Homo sapiens beta adaptin subunit pr...   137   3e-32
BC093739-1|AAH93739.1| 1082|Homo sapiens adaptor-related protein...    52   2e-06
AF022152-1|AAB71894.1| 1082|Homo sapiens AP-3 complex beta3B sub...    52   2e-06
U91931-1|AAD03778.1| 1093|Homo sapiens AP-3 complex beta3A subun...    49   1e-05
U81504-1|AAB61638.1| 1094|Homo sapiens beta-3A-adaptin subunit o...    49   1e-05
BC038444-1|AAH38444.1| 1094|Homo sapiens adaptor-related protein...    49   1e-05
AY623424-1|AAT49048.1|  800|Homo sapiens adaptor-related protein...    49   1e-05
U37673-1|AAC50219.1| 1081|Homo sapiens beta-NAP protein.               48   4e-05
BC014146-1|AAH14146.1|  739|Homo sapiens adaptor-related protein...    42   0.001
AL137856-9|CAI19074.1|  262|Homo sapiens adaptor-related protein...    42   0.001
AL137856-8|CAI19073.1|  296|Homo sapiens adaptor-related protein...    42   0.001
AL137856-7|CAI19075.1|  175|Homo sapiens adaptor-related protein...    42   0.001
AL137856-6|CAI19071.1|  571|Homo sapiens adaptor-related protein...    42   0.001
AL137856-5|CAI19072.1|  739|Homo sapiens adaptor-related protein...    42   0.001
AF092094-1|AAD20448.1|  739|Homo sapiens AP-4 adaptor complex be...    42   0.001
AB209817-1|BAD93054.1|  771|Homo sapiens adaptor-related protein...    42   0.001

>U36268-1|AAC50684.2|  949|Homo sapiens beta-prime-adaptin protein.
          Length = 949

 Score =  148 bits (358), Expect = 2e-35
 Identities = 71/85 (83%), Positives = 78/85 (91%)
 Frame = +1

Query: 253 ELMEMVSADTELVSTLSRKLAPPLVTLLSAEPEVQYVALRNINLVVQKRPDILKHEMKVF 432
           + MEM+S D +   TL +KLAPPLVTLLSAEPE+QYVALRNINL+VQKRP+ILKHEMKVF
Sbjct: 265 KFMEMLSKDLDYYGTLLKKLAPPLVTLLSAEPELQYVALRNINLIVQKRPEILKHEMKVF 324

Query: 433 FVKYNDPIYVKLEKLDIMIRLASQA 507
           FVKYNDPIYVKLEKLDIMIRLASQA
Sbjct: 325 FVKYNDPIYVKLEKLDIMIRLASQA 349



 Score =  126 bits (305), Expect = 5e-29
 Identities = 61/84 (72%), Positives = 72/84 (85%)
 Frame = +2

Query: 2   AALSEINEASVSGRPLVEMNAPTINKLLTALNECTEWGQVFILDALSNYSPRDAREAHSI 181
           AALSEI E+  S   L+++N  +INKLLTALNECTEWGQ+FILD L+NY P+D REA SI
Sbjct: 182 AALSEIAESHPSSN-LLDLNPQSINKLLTALNECTEWGQIFILDCLANYMPKDDREAQSI 240

Query: 182 CERITPRLAHANAAVVLSAVKVLM 253
           CER+TPRL+HAN+AVVLSAVKVLM
Sbjct: 241 CERVTPRLSHANSAVVLSAVKVLM 264



 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 36/40 (90%), Positives = 38/40 (95%)
 Frame = +3

Query: 504 SHIAQVLGELKEYATEVDVDFVRKAVRAIGRCAIKVEPSA 623
           ++IAQVL ELKEYATEVDVDFVRKAVRAIGRCAIKVE SA
Sbjct: 349 ANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSA 388


>L13939-1|AAC98702.1|  949|Homo sapiens beta-prime-adaptin protein.
          Length = 949

 Score =  148 bits (358), Expect = 2e-35
 Identities = 71/85 (83%), Positives = 78/85 (91%)
 Frame = +1

Query: 253 ELMEMVSADTELVSTLSRKLAPPLVTLLSAEPEVQYVALRNINLVVQKRPDILKHEMKVF 432
           + MEM+S D +   TL +KLAPPLVTLLSAEPE+QYVALRNINL+VQKRP+ILKHEMKVF
Sbjct: 265 KFMEMLSKDLDYYGTLLKKLAPPLVTLLSAEPELQYVALRNINLIVQKRPEILKHEMKVF 324

Query: 433 FVKYNDPIYVKLEKLDIMIRLASQA 507
           FVKYNDPIYVKLEKLDIMIRLASQA
Sbjct: 325 FVKYNDPIYVKLEKLDIMIRLASQA 349



 Score =  126 bits (305), Expect = 5e-29
 Identities = 61/84 (72%), Positives = 72/84 (85%)
 Frame = +2

Query: 2   AALSEINEASVSGRPLVEMNAPTINKLLTALNECTEWGQVFILDALSNYSPRDAREAHSI 181
           AALSEI E+  S   L+++N  +INKLLTALNECTEWGQ+FILD L+NY P+D REA SI
Sbjct: 182 AALSEIAESHPSSN-LLDLNPQSINKLLTALNECTEWGQIFILDCLANYMPKDDREAQSI 240

Query: 182 CERITPRLAHANAAVVLSAVKVLM 253
           CER+TPRL+HAN+AVVLSAVKVLM
Sbjct: 241 CERVTPRLSHANSAVVLSAVKVLM 264



 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 36/40 (90%), Positives = 38/40 (95%)
 Frame = +3

Query: 504 SHIAQVLGELKEYATEVDVDFVRKAVRAIGRCAIKVEPSA 623
           ++IAQVL ELKEYATEVDVDFVRKAVRAIGRCAIKVE SA
Sbjct: 349 ANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSA 388


>CT841508-1|CAJ86438.1|  939|Homo sapiens AP1B1 protein.
          Length = 939

 Score =  148 bits (358), Expect = 2e-35
 Identities = 71/85 (83%), Positives = 78/85 (91%)
 Frame = +1

Query: 253 ELMEMVSADTELVSTLSRKLAPPLVTLLSAEPEVQYVALRNINLVVQKRPDILKHEMKVF 432
           + MEM+S D +   TL +KLAPPLVTLLSAEPE+QYVALRNINL+VQKRP+ILKHEMKVF
Sbjct: 265 KFMEMLSKDLDYYGTLLKKLAPPLVTLLSAEPELQYVALRNINLIVQKRPEILKHEMKVF 324

Query: 433 FVKYNDPIYVKLEKLDIMIRLASQA 507
           FVKYNDPIYVKLEKLDIMIRLASQA
Sbjct: 325 FVKYNDPIYVKLEKLDIMIRLASQA 349



 Score =  126 bits (305), Expect = 5e-29
 Identities = 61/84 (72%), Positives = 72/84 (85%)
 Frame = +2

Query: 2   AALSEINEASVSGRPLVEMNAPTINKLLTALNECTEWGQVFILDALSNYSPRDAREAHSI 181
           AALSEI E+  S   L+++N  +INKLLTALNECTEWGQ+FILD L+NY P+D REA SI
Sbjct: 182 AALSEIAESHPSSN-LLDLNPQSINKLLTALNECTEWGQIFILDCLANYMPKDDREAQSI 240

Query: 182 CERITPRLAHANAAVVLSAVKVLM 253
           CER+TPRL+HAN+AVVLSAVKVLM
Sbjct: 241 CERVTPRLSHANSAVVLSAVKVLM 264



 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 36/40 (90%), Positives = 38/40 (95%)
 Frame = +3

Query: 504 SHIAQVLGELKEYATEVDVDFVRKAVRAIGRCAIKVEPSA 623
           ++IAQVL ELKEYATEVDVDFVRKAVRAIGRCAIKVE SA
Sbjct: 349 ANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSA 388


>BC046242-1|AAH46242.1|  919|Homo sapiens AP1B1 protein protein.
          Length = 919

 Score =  148 bits (358), Expect = 2e-35
 Identities = 71/85 (83%), Positives = 78/85 (91%)
 Frame = +1

Query: 253 ELMEMVSADTELVSTLSRKLAPPLVTLLSAEPEVQYVALRNINLVVQKRPDILKHEMKVF 432
           + MEM+S D +   TL +KLAPPLVTLLSAEPE+QYVALRNINL+VQKRP+ILKHEMKVF
Sbjct: 265 KFMEMLSKDLDYYGTLLKKLAPPLVTLLSAEPELQYVALRNINLIVQKRPEILKHEMKVF 324

Query: 433 FVKYNDPIYVKLEKLDIMIRLASQA 507
           FVKYNDPIYVKLEKLDIMIRLASQA
Sbjct: 325 FVKYNDPIYVKLEKLDIMIRLASQA 349



 Score =  126 bits (305), Expect = 5e-29
 Identities = 61/84 (72%), Positives = 72/84 (85%)
 Frame = +2

Query: 2   AALSEINEASVSGRPLVEMNAPTINKLLTALNECTEWGQVFILDALSNYSPRDAREAHSI 181
           AALSEI E+  S   L+++N  +INKLLTALNECTEWGQ+FILD L+NY P+D REA SI
Sbjct: 182 AALSEIAESHPSSN-LLDLNPQSINKLLTALNECTEWGQIFILDCLANYMPKDDREAQSI 240

Query: 182 CERITPRLAHANAAVVLSAVKVLM 253
           CER+TPRL+HAN+AVVLSAVKVLM
Sbjct: 241 CERVTPRLSHANSAVVLSAVKVLM 264



 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 36/40 (90%), Positives = 38/40 (95%)
 Frame = +3

Query: 504 SHIAQVLGELKEYATEVDVDFVRKAVRAIGRCAIKVEPSA 623
           ++IAQVL ELKEYATEVDVDFVRKAVRAIGRCAIKVE SA
Sbjct: 349 ANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSA 388


>M34175-1|AAA35583.1|  937|Homo sapiens protein ( Human beta adaptin
           mRNA, complete cds. ).
          Length = 937

 Score =  137 bits (331), Expect = 3e-32
 Identities = 65/85 (76%), Positives = 76/85 (89%)
 Frame = +1

Query: 253 ELMEMVSADTELVSTLSRKLAPPLVTLLSAEPEVQYVALRNINLVVQKRPDILKHEMKVF 432
           + +E++  D++  + L +KLAPPLVTLLS EPEVQYVALRNINL+VQKRP+ILK E+KVF
Sbjct: 265 KFLELLPKDSDYYNMLLKKLAPPLVTLLSGEPEVQYVALRNINLIVQKRPEILKQEIKVF 324

Query: 433 FVKYNDPIYVKLEKLDIMIRLASQA 507
           FVKYNDPIYVKLEKLDIMIRLASQA
Sbjct: 325 FVKYNDPIYVKLEKLDIMIRLASQA 349



 Score =  128 bits (309), Expect = 2e-29
 Identities = 61/84 (72%), Positives = 73/84 (86%)
 Frame = +2

Query: 2   AALSEINEASVSGRPLVEMNAPTINKLLTALNECTEWGQVFILDALSNYSPRDAREAHSI 181
           AALSEI+E+  +   L+++N   INKLLTALNECTEWGQ+FILD LSNY+P+D REA SI
Sbjct: 182 AALSEISESHPNSN-LLDLNPQNINKLLTALNECTEWGQIFILDCLSNYNPKDDREAQSI 240

Query: 182 CERITPRLAHANAAVVLSAVKVLM 253
           CER+TPRL+HAN+AVVLSAVKVLM
Sbjct: 241 CERVTPRLSHANSAVVLSAVKVLM 264



 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 36/40 (90%), Positives = 38/40 (95%)
 Frame = +3

Query: 504 SHIAQVLGELKEYATEVDVDFVRKAVRAIGRCAIKVEPSA 623
           ++IAQVL ELKEYATEVDVDFVRKAVRAIGRCAIKVE SA
Sbjct: 349 ANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSA 388


>BC006201-1|AAH06201.1|  951|Homo sapiens adaptor-related protein
           complex 2, beta 1 subunit protein.
          Length = 951

 Score =  137 bits (331), Expect = 3e-32
 Identities = 65/85 (76%), Positives = 76/85 (89%)
 Frame = +1

Query: 253 ELMEMVSADTELVSTLSRKLAPPLVTLLSAEPEVQYVALRNINLVVQKRPDILKHEMKVF 432
           + +E++  D++  + L +KLAPPLVTLLS EPEVQYVALRNINL+VQKRP+ILK E+KVF
Sbjct: 265 KFLELLPKDSDYYNMLLKKLAPPLVTLLSGEPEVQYVALRNINLIVQKRPEILKQEIKVF 324

Query: 433 FVKYNDPIYVKLEKLDIMIRLASQA 507
           FVKYNDPIYVKLEKLDIMIRLASQA
Sbjct: 325 FVKYNDPIYVKLEKLDIMIRLASQA 349



 Score =  128 bits (309), Expect = 2e-29
 Identities = 61/84 (72%), Positives = 73/84 (86%)
 Frame = +2

Query: 2   AALSEINEASVSGRPLVEMNAPTINKLLTALNECTEWGQVFILDALSNYSPRDAREAHSI 181
           AALSEI+E+  +   L+++N   INKLLTALNECTEWGQ+FILD LSNY+P+D REA SI
Sbjct: 182 AALSEISESHPNSN-LLDLNPQNINKLLTALNECTEWGQIFILDCLSNYNPKDDREAQSI 240

Query: 182 CERITPRLAHANAAVVLSAVKVLM 253
           CER+TPRL+HAN+AVVLSAVKVLM
Sbjct: 241 CERVTPRLSHANSAVVLSAVKVLM 264



 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 36/40 (90%), Positives = 38/40 (95%)
 Frame = +3

Query: 504 SHIAQVLGELKEYATEVDVDFVRKAVRAIGRCAIKVEPSA 623
           ++IAQVL ELKEYATEVDVDFVRKAVRAIGRCAIKVE SA
Sbjct: 349 ANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSA 388


>AY341427-1|AAQ20044.1|  880|Homo sapiens beta adaptin subunit
           protein.
          Length = 880

 Score =  137 bits (331), Expect = 3e-32
 Identities = 65/85 (76%), Positives = 76/85 (89%)
 Frame = +1

Query: 253 ELMEMVSADTELVSTLSRKLAPPLVTLLSAEPEVQYVALRNINLVVQKRPDILKHEMKVF 432
           + +E++  D++  + L +KLAPPLVTLLS EPEVQYVALRNINL+VQKRP+ILK E+KVF
Sbjct: 208 KFLELLPKDSDYYNMLLKKLAPPLVTLLSGEPEVQYVALRNINLIVQKRPEILKQEIKVF 267

Query: 433 FVKYNDPIYVKLEKLDIMIRLASQA 507
           FVKYNDPIYVKLEKLDIMIRLASQA
Sbjct: 268 FVKYNDPIYVKLEKLDIMIRLASQA 292



 Score =  128 bits (309), Expect = 2e-29
 Identities = 61/84 (72%), Positives = 73/84 (86%)
 Frame = +2

Query: 2   AALSEINEASVSGRPLVEMNAPTINKLLTALNECTEWGQVFILDALSNYSPRDAREAHSI 181
           AALSEI+E+  +   L+++N   INKLLTALNECTEWGQ+FILD LSNY+P+D REA SI
Sbjct: 125 AALSEISESHPNSN-LLDLNPQNINKLLTALNECTEWGQIFILDCLSNYNPKDDREAQSI 183

Query: 182 CERITPRLAHANAAVVLSAVKVLM 253
           CER+TPRL+HAN+AVVLSAVKVLM
Sbjct: 184 CERVTPRLSHANSAVVLSAVKVLM 207



 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 36/40 (90%), Positives = 38/40 (95%)
 Frame = +3

Query: 504 SHIAQVLGELKEYATEVDVDFVRKAVRAIGRCAIKVEPSA 623
           ++IAQVL ELKEYATEVDVDFVRKAVRAIGRCAIKVE SA
Sbjct: 292 ANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSA 331


>BC093739-1|AAH93739.1| 1082|Homo sapiens adaptor-related protein
           complex 3, beta 2 subunit protein.
          Length = 1082

 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 24/69 (34%), Positives = 42/69 (60%)
 Frame = +1

Query: 310 LAPPLVTLLSAEPEVQYVALRNINLVVQKRPDILKHEMKVFFVKYNDPIYVKLEKLDIMI 489
           +A  LV LL +  EVQYV L+N+  +  KR  + +  +K F+++  DP  +K+ KL+++ 
Sbjct: 340 IAKALVRLLRSHSEVQYVVLQNVATMSIKRRGMFEPYLKSFYIRSTDPTQIKILKLEVLT 399

Query: 490 RLASQAT*P 516
            LA++   P
Sbjct: 400 NLANETNIP 408



 Score = 35.1 bits (77), Expect = 0.20
 Identities = 15/36 (41%), Positives = 22/36 (61%)
 Frame = +3

Query: 504 SHIAQVLGELKEYATEVDVDFVRKAVRAIGRCAIKV 611
           ++I  VL E + Y   +D DFV   ++AIGRCA  +
Sbjct: 405 TNIPTVLREFQTYIRSMDKDFVAATIQAIGRCATNI 440


>AF022152-1|AAB71894.1| 1082|Homo sapiens AP-3 complex beta3B
           subunit protein.
          Length = 1082

 Score = 52.0 bits (119), Expect = 2e-06
 Identities = 24/69 (34%), Positives = 42/69 (60%)
 Frame = +1

Query: 310 LAPPLVTLLSAEPEVQYVALRNINLVVQKRPDILKHEMKVFFVKYNDPIYVKLEKLDIMI 489
           +A  LV LL +  EVQYV L+N+  +  KR  + +  +K F+++  DP  +K+ KL+++ 
Sbjct: 340 IAKALVRLLRSHSEVQYVVLQNVATMSIKRRGMFEPYLKSFYIRSTDPTQIKILKLEVLT 399

Query: 490 RLASQAT*P 516
            LA++   P
Sbjct: 400 NLANETNIP 408



 Score = 35.1 bits (77), Expect = 0.20
 Identities = 15/36 (41%), Positives = 22/36 (61%)
 Frame = +3

Query: 504 SHIAQVLGELKEYATEVDVDFVRKAVRAIGRCAIKV 611
           ++I  VL E + Y   +D DFV   ++AIGRCA  +
Sbjct: 405 TNIPTVLREFQTYIRSMDKDFVAATIQAIGRCATNI 440


>U91931-1|AAD03778.1| 1093|Homo sapiens AP-3 complex beta3A subunit
           protein.
          Length = 1093

 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 24/66 (36%), Positives = 41/66 (62%)
 Frame = +1

Query: 310 LAPPLVTLLSAEPEVQYVALRNINLVVQKRPDILKHEMKVFFVKYNDPIYVKLEKLDIMI 489
           ++  LV LL +  EVQY+ L+NI  +  +R  + +  +K F+V+  DP  +K  KL+I+ 
Sbjct: 335 ISKSLVRLLRSNREVQYIVLQNIATMSIQRKGMFEPYLKSFYVRSTDPTMIKTLKLEILT 394

Query: 490 RLASQA 507
            LA++A
Sbjct: 395 NLANEA 400


>U81504-1|AAB61638.1| 1094|Homo sapiens beta-3A-adaptin subunit of
           the AP-3 complex protein.
          Length = 1094

 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 24/66 (36%), Positives = 41/66 (62%)
 Frame = +1

Query: 310 LAPPLVTLLSAEPEVQYVALRNINLVVQKRPDILKHEMKVFFVKYNDPIYVKLEKLDIMI 489
           ++  LV LL +  EVQY+ L+NI  +  +R  + +  +K F+V+  DP  +K  KL+I+ 
Sbjct: 335 ISKSLVRLLRSNREVQYIVLQNIATMSIQRKGMFEPYLKSFYVRSTDPTMIKTLKLEILT 394

Query: 490 RLASQA 507
            LA++A
Sbjct: 395 NLANEA 400


>BC038444-1|AAH38444.1| 1094|Homo sapiens adaptor-related protein
           complex 3, beta 1 subunit protein.
          Length = 1094

 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 24/66 (36%), Positives = 41/66 (62%)
 Frame = +1

Query: 310 LAPPLVTLLSAEPEVQYVALRNINLVVQKRPDILKHEMKVFFVKYNDPIYVKLEKLDIMI 489
           ++  LV LL +  EVQY+ L+NI  +  +R  + +  +K F+V+  DP  +K  KL+I+ 
Sbjct: 335 ISKSLVRLLRSNREVQYIVLQNIATMSIQRKGMFEPYLKSFYVRSTDPTMIKTLKLEILT 394

Query: 490 RLASQA 507
            LA++A
Sbjct: 395 NLANEA 400


>AY623424-1|AAT49048.1|  800|Homo sapiens adaptor-related protein
           complex 3 beta 1 subunit protein.
          Length = 800

 Score = 49.2 bits (112), Expect = 1e-05
 Identities = 24/66 (36%), Positives = 41/66 (62%)
 Frame = +1

Query: 310 LAPPLVTLLSAEPEVQYVALRNINLVVQKRPDILKHEMKVFFVKYNDPIYVKLEKLDIMI 489
           ++  LV LL +  EVQY+ L+NI  +  +R  + +  +K F+V+  DP  +K  KL+I+ 
Sbjct: 335 ISKSLVRLLRSNREVQYIVLQNIATMSIQRKGMFEPYLKSFYVRSTDPTMIKTLKLEILT 394

Query: 490 RLASQA 507
            LA++A
Sbjct: 395 NLANEA 400


>U37673-1|AAC50219.1| 1081|Homo sapiens beta-NAP protein.
          Length = 1081

 Score = 47.6 bits (108), Expect = 4e-05
 Identities = 21/62 (33%), Positives = 38/62 (61%)
 Frame = +1

Query: 331 LLSAEPEVQYVALRNINLVVQKRPDILKHEMKVFFVKYNDPIYVKLEKLDIMIRLASQAT 510
           LL +  EVQYV L+N+  +  KR  + +  +K F+++  DP  +K+ KL+++  LA++  
Sbjct: 346 LLRSHSEVQYVVLQNVATMSIKRRGMFEPYLKSFYIRSTDPTQIKILKLEVLTNLANETN 405

Query: 511 *P 516
            P
Sbjct: 406 IP 407



 Score = 35.1 bits (77), Expect = 0.20
 Identities = 15/36 (41%), Positives = 22/36 (61%)
 Frame = +3

Query: 504 SHIAQVLGELKEYATEVDVDFVRKAVRAIGRCAIKV 611
           ++I  VL E + Y   +D DFV   ++AIGRCA  +
Sbjct: 404 TNIPTVLREFQTYIRSMDKDFVAATIQAIGRCATNI 439


>BC014146-1|AAH14146.1|  739|Homo sapiens adaptor-related protein
           complex 4, beta 1 subunit protein.
          Length = 739

 Score = 42.3 bits (95), Expect = 0.001
 Identities = 20/68 (29%), Positives = 34/68 (50%)
 Frame = +2

Query: 50  VEMNAPTINKLLTALNECTEWGQVFILDALSNYSPRDAREAHSICERITPRLAHANAAVV 229
           V +N P  + LL  +++  +WGQ  +L+ L  Y PR   E   I   +   L  ++  VV
Sbjct: 193 VVINKPIAHHLLNRMSKLDQWGQAEVLNFLLRYQPRSEEELFDILNLLDSFLKSSSPGVV 252

Query: 230 LSAVKVLM 253
           + A K+ +
Sbjct: 253 MGATKLFL 260



 Score = 42.3 bits (95), Expect = 0.001
 Identities = 20/68 (29%), Positives = 35/68 (51%)
 Frame = +1

Query: 298 LSRKLAPPLVTLLSAEPEVQYVALRNINLVVQKRPDILKHEMKVFFVKYNDPIYVKLEKL 477
           L R   P L    S   E+ +VAL ++  ++   P       K FF  Y++P Y+KL+K+
Sbjct: 274 LVRVKGPLLAACSSESRELCFVALCHVRQILHSLPGHFSSHYKKFFCSYSEPHYIKLQKV 333

Query: 478 DIMIRLAS 501
           +++  L +
Sbjct: 334 EVLCELVN 341



 Score = 33.1 bits (72), Expect = 0.82
 Identities = 15/32 (46%), Positives = 21/32 (65%)
 Frame = +3

Query: 507 HIAQVLGELKEYATEVDVDFVRKAVRAIGRCA 602
           ++ QVL EL+ Y T+V  DF + A+ AIG  A
Sbjct: 344 NVQQVLEELRGYCTDVSADFAQAAIFAIGGIA 375


>AL137856-9|CAI19074.1|  262|Homo sapiens adaptor-related protein
           complex 4, beta 1 subunit protein.
          Length = 262

 Score = 42.3 bits (95), Expect = 0.001
 Identities = 20/68 (29%), Positives = 34/68 (50%)
 Frame = +2

Query: 50  VEMNAPTINKLLTALNECTEWGQVFILDALSNYSPRDAREAHSICERITPRLAHANAAVV 229
           V +N P  + LL  +++  +WGQ  +L+ L  Y PR   E   I   +   L  ++  VV
Sbjct: 193 VVINKPIAHHLLNRMSKLDQWGQAEVLNFLLRYQPRSEEELFDILNLLDSFLKSSSPGVV 252

Query: 230 LSAVKVLM 253
           + A K+ +
Sbjct: 253 MGATKLFL 260


>AL137856-8|CAI19073.1|  296|Homo sapiens adaptor-related protein
           complex 4, beta 1 subunit protein.
          Length = 296

 Score = 42.3 bits (95), Expect = 0.001
 Identities = 20/68 (29%), Positives = 34/68 (50%)
 Frame = +2

Query: 50  VEMNAPTINKLLTALNECTEWGQVFILDALSNYSPRDAREAHSICERITPRLAHANAAVV 229
           V +N P  + LL  +++  +WGQ  +L+ L  Y PR   E   I   +   L  ++  VV
Sbjct: 118 VVINKPIAHHLLNRMSKLDQWGQAEVLNFLLRYQPRSEEELFDILNLLDSFLKSSSPGVV 177

Query: 230 LSAVKVLM 253
           + A K+ +
Sbjct: 178 MGATKLFL 185



 Score = 42.3 bits (95), Expect = 0.001
 Identities = 20/68 (29%), Positives = 35/68 (51%)
 Frame = +1

Query: 298 LSRKLAPPLVTLLSAEPEVQYVALRNINLVVQKRPDILKHEMKVFFVKYNDPIYVKLEKL 477
           L R   P L    S   E+ +VAL ++  ++   P       K FF  Y++P Y+KL+K+
Sbjct: 199 LVRVKGPLLAACSSESRELCFVALCHVRQILHSLPGHFSSHYKKFFCSYSEPHYIKLQKV 258

Query: 478 DIMIRLAS 501
           +++  L +
Sbjct: 259 EVLCELVN 266



 Score = 30.3 bits (65), Expect = 5.8
 Identities = 13/28 (46%), Positives = 19/28 (67%)
 Frame = +3

Query: 507 HIAQVLGELKEYATEVDVDFVRKAVRAI 590
           ++ QVL EL+ Y T+V  DF + A+ AI
Sbjct: 269 NVQQVLEELRGYCTDVSADFAQAAIFAI 296


>AL137856-7|CAI19075.1|  175|Homo sapiens adaptor-related protein
           complex 4, beta 1 subunit protein.
          Length = 175

 Score = 42.3 bits (95), Expect = 0.001
 Identities = 20/68 (29%), Positives = 35/68 (51%)
 Frame = +1

Query: 298 LSRKLAPPLVTLLSAEPEVQYVALRNINLVVQKRPDILKHEMKVFFVKYNDPIYVKLEKL 477
           L R   P L    S   E+ +VAL ++  ++   P       K FF  Y++P Y+KL+K+
Sbjct: 106 LVRVKGPLLAACSSESRELCFVALCHVRQILHSLPGHFSSHYKKFFCSYSEPHYIKLQKV 165

Query: 478 DIMIRLAS 501
           +++  L +
Sbjct: 166 EVLCELVN 173



 Score = 34.3 bits (75), Expect = 0.36
 Identities = 15/54 (27%), Positives = 27/54 (50%)
 Frame = +2

Query: 92  LNECTEWGQVFILDALSNYSPRDAREAHSICERITPRLAHANAAVVLSAVKVLM 253
           +++  +WGQ  +L+ L  Y PR   E   I   +   L  ++  VV+ A K+ +
Sbjct: 39  MSKLDQWGQAEVLNFLLRYQPRSEEELFDILNLLDSFLKSSSPGVVMGATKLFL 92


>AL137856-6|CAI19071.1|  571|Homo sapiens adaptor-related protein
           complex 4, beta 1 subunit protein.
          Length = 571

 Score = 42.3 bits (95), Expect = 0.001
 Identities = 20/68 (29%), Positives = 35/68 (51%)
 Frame = +1

Query: 298 LSRKLAPPLVTLLSAEPEVQYVALRNINLVVQKRPDILKHEMKVFFVKYNDPIYVKLEKL 477
           L R   P L    S   E+ +VAL ++  ++   P       K FF  Y++P Y+KL+K+
Sbjct: 106 LVRVKGPLLAACSSESRELCFVALCHVRQILHSLPGHFSSHYKKFFCSYSEPHYIKLQKV 165

Query: 478 DIMIRLAS 501
           +++  L +
Sbjct: 166 EVLCELVN 173



 Score = 34.3 bits (75), Expect = 0.36
 Identities = 15/54 (27%), Positives = 27/54 (50%)
 Frame = +2

Query: 92  LNECTEWGQVFILDALSNYSPRDAREAHSICERITPRLAHANAAVVLSAVKVLM 253
           +++  +WGQ  +L+ L  Y PR   E   I   +   L  ++  VV+ A K+ +
Sbjct: 39  MSKLDQWGQAEVLNFLLRYQPRSEEELFDILNLLDSFLKSSSPGVVMGATKLFL 92



 Score = 33.1 bits (72), Expect = 0.82
 Identities = 15/32 (46%), Positives = 21/32 (65%)
 Frame = +3

Query: 507 HIAQVLGELKEYATEVDVDFVRKAVRAIGRCA 602
           ++ QVL EL+ Y T+V  DF + A+ AIG  A
Sbjct: 176 NVQQVLEELRGYCTDVSADFAQAAIFAIGGIA 207


>AL137856-5|CAI19072.1|  739|Homo sapiens adaptor-related protein
           complex 4, beta 1 subunit protein.
          Length = 739

 Score = 42.3 bits (95), Expect = 0.001
 Identities = 20/68 (29%), Positives = 34/68 (50%)
 Frame = +2

Query: 50  VEMNAPTINKLLTALNECTEWGQVFILDALSNYSPRDAREAHSICERITPRLAHANAAVV 229
           V +N P  + LL  +++  +WGQ  +L+ L  Y PR   E   I   +   L  ++  VV
Sbjct: 193 VVINKPIAHHLLNRMSKLDQWGQAEVLNFLLRYQPRSEEELFDILNLLDSFLKSSSPGVV 252

Query: 230 LSAVKVLM 253
           + A K+ +
Sbjct: 253 MGATKLFL 260



 Score = 42.3 bits (95), Expect = 0.001
 Identities = 20/68 (29%), Positives = 35/68 (51%)
 Frame = +1

Query: 298 LSRKLAPPLVTLLSAEPEVQYVALRNINLVVQKRPDILKHEMKVFFVKYNDPIYVKLEKL 477
           L R   P L    S   E+ +VAL ++  ++   P       K FF  Y++P Y+KL+K+
Sbjct: 274 LVRVKGPLLAACSSESRELCFVALCHVRQILHSLPGHFSSHYKKFFCSYSEPHYIKLQKV 333

Query: 478 DIMIRLAS 501
           +++  L +
Sbjct: 334 EVLCELVN 341



 Score = 33.1 bits (72), Expect = 0.82
 Identities = 15/32 (46%), Positives = 21/32 (65%)
 Frame = +3

Query: 507 HIAQVLGELKEYATEVDVDFVRKAVRAIGRCA 602
           ++ QVL EL+ Y T+V  DF + A+ AIG  A
Sbjct: 344 NVQQVLEELRGYCTDVSADFAQAAIFAIGGIA 375


>AF092094-1|AAD20448.1|  739|Homo sapiens AP-4 adaptor complex beta4
           subunit protein.
          Length = 739

 Score = 42.3 bits (95), Expect = 0.001
 Identities = 20/68 (29%), Positives = 34/68 (50%)
 Frame = +2

Query: 50  VEMNAPTINKLLTALNECTEWGQVFILDALSNYSPRDAREAHSICERITPRLAHANAAVV 229
           V +N P  + LL  +++  +WGQ  +L+ L  Y PR   E   I   +   L  ++  VV
Sbjct: 193 VVINKPIAHHLLNRMSKLDQWGQAEVLNFLLRYQPRSEEELFDILNLLDSFLKSSSPGVV 252

Query: 230 LSAVKVLM 253
           + A K+ +
Sbjct: 253 MGATKLFL 260



 Score = 42.3 bits (95), Expect = 0.001
 Identities = 20/68 (29%), Positives = 35/68 (51%)
 Frame = +1

Query: 298 LSRKLAPPLVTLLSAEPEVQYVALRNINLVVQKRPDILKHEMKVFFVKYNDPIYVKLEKL 477
           L R   P L    S   E+ +VAL ++  ++   P       K FF  Y++P Y+KL+K+
Sbjct: 274 LVRVKGPLLAACSSESRELCFVALCHVRQILHSLPGHFSSHYKKFFCSYSEPHYIKLQKV 333

Query: 478 DIMIRLAS 501
           +++  L +
Sbjct: 334 EVLCELVN 341



 Score = 33.1 bits (72), Expect = 0.82
 Identities = 15/32 (46%), Positives = 21/32 (65%)
 Frame = +3

Query: 507 HIAQVLGELKEYATEVDVDFVRKAVRAIGRCA 602
           ++ QVL EL+ Y T+V  DF + A+ AIG  A
Sbjct: 344 NVQQVLEELRGYCTDVSADFAQAAIFAIGGIA 375


>AB209817-1|BAD93054.1|  771|Homo sapiens adaptor-related protein
           complex 4, beta 1 subunit variant protein.
          Length = 771

 Score = 42.3 bits (95), Expect = 0.001
 Identities = 20/68 (29%), Positives = 34/68 (50%)
 Frame = +2

Query: 50  VEMNAPTINKLLTALNECTEWGQVFILDALSNYSPRDAREAHSICERITPRLAHANAAVV 229
           V +N P  + LL  +++  +WGQ  +L+ L  Y PR   E   I   +   L  ++  VV
Sbjct: 225 VVINKPIAHHLLNRMSKLDQWGQAEVLNFLLRYQPRSEEELFDILNLLDSFLKSSSPGVV 284

Query: 230 LSAVKVLM 253
           + A K+ +
Sbjct: 285 MGATKLFL 292



 Score = 42.3 bits (95), Expect = 0.001
 Identities = 20/68 (29%), Positives = 35/68 (51%)
 Frame = +1

Query: 298 LSRKLAPPLVTLLSAEPEVQYVALRNINLVVQKRPDILKHEMKVFFVKYNDPIYVKLEKL 477
           L R   P L    S   E+ +VAL ++  ++   P       K FF  Y++P Y+KL+K+
Sbjct: 306 LVRVKGPLLAACSSESRELCFVALCHVRQILHSLPGHFSSHYKKFFCSYSEPHYIKLQKV 365

Query: 478 DIMIRLAS 501
           +++  L +
Sbjct: 366 EVLCELVN 373



 Score = 33.1 bits (72), Expect = 0.82
 Identities = 15/32 (46%), Positives = 21/32 (65%)
 Frame = +3

Query: 507 HIAQVLGELKEYATEVDVDFVRKAVRAIGRCA 602
           ++ QVL EL+ Y T+V  DF + A+ AIG  A
Sbjct: 376 NVQQVLEELRGYCTDVSADFAQAAIFAIGGIA 407


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 81,505,530
Number of Sequences: 237096
Number of extensions: 1516250
Number of successful extensions: 7745
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 7576
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7745
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6747805200
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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