Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= NV021005
(734 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q7JX82 Cluster: GH21964p; n=3; Endopterygota|Rep: GH219... 138 2e-31
UniRef50_UPI0000F2CA50 Cluster: PREDICTED: similar to PDZ domain... 123 5e-27
UniRef50_O14908 Cluster: PDZ domain-containing protein GIPC1; n=... 122 1e-26
UniRef50_UPI00005848B6 Cluster: PREDICTED: similar to GIPC1 prot... 105 1e-21
UniRef50_Q5DI42 Cluster: SJCHGC06361 protein; n=1; Schistosoma j... 85 2e-15
UniRef50_Q18488 Cluster: Putative uncharacterized protein; n=3; ... 66 8e-10
UniRef50_UPI0000F1F559 Cluster: PREDICTED: hypothetical protein;... 35 1.8
UniRef50_Q4SG56 Cluster: Chromosome 17 SCAF14597, whole genome s... 35 2.4
UniRef50_Q99NE5-4 Cluster: Isoform 4 of Q99NE5 ; n=6; Tetrapoda|... 34 4.2
UniRef50_Q4SWT6 Cluster: Chromosome 11 SCAF13518, whole genome s... 34 4.2
UniRef50_Q9JIR4 Cluster: Regulating synaptic membrane exocytosis... 34 4.2
UniRef50_Q99NE5 Cluster: Regulating synaptic membrane exocytosis... 34 4.2
UniRef50_P54936 Cluster: Protein lin-2; n=3; Caenorhabditis|Rep:... 34 4.2
UniRef50_Q4JTP8 Cluster: Two-component system sensor kinase MtrB... 33 5.5
UniRef50_P48371 Cluster: DNA gyrase subunit A; n=456; cellular o... 33 7.3
UniRef50_A0BIK3 Cluster: Chromosome undetermined scaffold_11, wh... 33 9.6
UniRef50_Q8J2X1 Cluster: Putative uncharacterized protein; n=3; ... 33 9.6
UniRef50_Q86UR5 Cluster: Regulating synaptic membrane exocytosis... 33 9.6
>UniRef50_Q7JX82 Cluster: GH21964p; n=3; Endopterygota|Rep: GH21964p
- Drosophila melanogaster (Fruit fly)
Length = 336
Score = 138 bits (333), Expect = 2e-31
Identities = 64/75 (85%), Positives = 70/75 (93%)
Frame = +1
Query: 508 QVDMKKLLGGQIGLEDFIFAHRKGRPKEIEIVKTEDALGLTITDNGAGYAFIKRIKEGSI 687
+VDM +LLGGQIGL+DFIFAHRKGRPKEIEIVK++DALGLTITDNGAGYAFIKRIKE SI
Sbjct: 101 KVDMTRLLGGQIGLDDFIFAHRKGRPKEIEIVKSQDALGLTITDNGAGYAFIKRIKEDSI 160
Query: 688 VXRIPHIEVGDHIEK 732
+ RI HI VGDHIEK
Sbjct: 161 IDRIEHISVGDHIEK 175
Score = 88.2 bits (209), Expect = 2e-16
Identities = 41/70 (58%), Positives = 51/70 (72%), Gaps = 5/70 (7%)
Frame = +2
Query: 317 SQST*VDNSNGTQ-----KSQLVFHCQQAHGSPLGLISGFSNVKELYEKIAECYEFSPED 481
SQ + + N+N K LVFHCQ AHGSP GLI FS+V+ELY+KIAEC++ S +D
Sbjct: 32 SQGSHISNNNNNSIPEKTKPPLVFHCQLAHGSPTGLIHDFSSVRELYQKIAECFDISEKD 91
Query: 482 ILFCTLNTHK 511
ILFCTLN+HK
Sbjct: 92 ILFCTLNSHK 101
>UniRef50_UPI0000F2CA50 Cluster: PREDICTED: similar to PDZ domain
protein GIPC3; n=1; Monodelphis domestica|Rep:
PREDICTED: similar to PDZ domain protein GIPC3 -
Monodelphis domestica
Length = 412
Score = 123 bits (296), Expect = 5e-27
Identities = 58/74 (78%), Positives = 65/74 (87%)
Frame = +1
Query: 508 QVDMKKLLGGQIGLEDFIFAHRKGRPKEIEIVKTEDALGLTITDNGAGYAFIKRIKEGSI 687
+VDM+KLLGGQIGLEDFIFAH +G KE+E+ KTEDALGLTITDNGAGYAFIKRIKEGSI
Sbjct: 185 KVDMQKLLGGQIGLEDFIFAHVRGETKEVEVTKTEDALGLTITDNGAGYAFIKRIKEGSI 244
Query: 688 VXRIPHIEVGDHIE 729
+ RI + VGD IE
Sbjct: 245 INRIEAVCVGDSIE 258
Score = 78.6 bits (185), Expect = 1e-13
Identities = 34/52 (65%), Positives = 41/52 (78%)
Frame = +2
Query: 356 KSQLVFHCQQAHGSPLGLISGFSNVKELYEKIAECYEFSPEDILFCTLNTHK 511
+ +LVFH Q AHGSP G I GF+NV+ELY KIAE + SP +ILFCTLN+HK
Sbjct: 134 RPRLVFHTQLAHGSPTGKIEGFTNVRELYAKIAEAFGISPTEILFCTLNSHK 185
>UniRef50_O14908 Cluster: PDZ domain-containing protein GIPC1; n=55;
Eumetazoa|Rep: PDZ domain-containing protein GIPC1 -
Homo sapiens (Human)
Length = 333
Score = 122 bits (293), Expect = 1e-26
Identities = 60/89 (67%), Positives = 68/89 (76%)
Frame = +1
Query: 463 RIFTRRYSFLYFKYSQVDMKKLLGGQIGLEDFIFAHRKGRPKEIEIVKTEDALGLTITDN 642
R+ T F +VDM KLLGGQIGLEDFIFAH KG+ KE+E+ K+EDALGLTITDN
Sbjct: 91 RLPTAEVMFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDN 150
Query: 643 GAGYAFIKRIKEGSIVXRIPHIEVGDHIE 729
GAGYAFIKRIKEGS++ I I VGD IE
Sbjct: 151 GAGYAFIKRIKEGSVIDHIHLISVGDMIE 179
Score = 75.4 bits (177), Expect = 1e-12
Identities = 32/52 (61%), Positives = 39/52 (75%)
Frame = +2
Query: 356 KSQLVFHCQQAHGSPLGLISGFSNVKELYEKIAECYEFSPEDILFCTLNTHK 511
+ +LVFH Q AHGSP G I GF+NVKELY KIAE + +++FCTLNTHK
Sbjct: 55 RPRLVFHTQLAHGSPTGRIEGFTNVKELYGKIAEAFRLPTAEVMFCTLNTHK 106
>UniRef50_UPI00005848B6 Cluster: PREDICTED: similar to GIPC1
protein; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to GIPC1 protein - Strongylocentrotus
purpuratus
Length = 369
Score = 105 bits (252), Expect = 1e-21
Identities = 51/75 (68%), Positives = 59/75 (78%)
Frame = +1
Query: 508 QVDMKKLLGGQIGLEDFIFAHRKGRPKEIEIVKTEDALGLTITDNGAGYAFIKRIKEGSI 687
+ DM KLLGGQIGL D I+AH KG+ EI + K E ALGLTITDNGAGYAF+KRIKEGSI
Sbjct: 128 KTDMDKLLGGQIGLSDSIYAHIKGQKFEIAVNKVEAALGLTITDNGAGYAFVKRIKEGSI 187
Query: 688 VXRIPHIEVGDHIEK 732
+ + +EVGDHI K
Sbjct: 188 MEKNGFVEVGDHIVK 202
Score = 65.7 bits (153), Expect = 1e-09
Identities = 33/64 (51%), Positives = 42/64 (65%)
Frame = +2
Query: 320 QST*VDNSNGTQKSQLVFHCQQAHGSPLGLISGFSNVKELYEKIAECYEFSPEDILFCTL 499
QST ++N+ + +LVF AHGSP + GF+NVKELYEKI E + +ILFCTL
Sbjct: 66 QST-MNNAPPPKPQRLVFSAFLAHGSPPAKVEGFTNVKELYEKIGEGFSMPASEILFCTL 124
Query: 500 NTHK 511
NT K
Sbjct: 125 NTFK 128
>UniRef50_Q5DI42 Cluster: SJCHGC06361 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC06361 protein - Schistosoma
japonicum (Blood fluke)
Length = 328
Score = 84.6 bits (200), Expect = 2e-15
Identities = 42/80 (52%), Positives = 54/80 (67%), Gaps = 5/80 (6%)
Frame = +1
Query: 508 QVDMKKLLGGQIGLEDFIFAHRKGRPKEIEIVKTEDALGLTITDNGAGYAFIKRIKEGSI 687
++DM KLL +IGL DF+FAH KG+PKEI+I KT ++ GLT+TDNG G IKRIK G
Sbjct: 80 KLDMDKLLSYEIGLNDFLFAHIKGQPKEIKIRKTSESFGLTLTDNGCGVVIIKRIKPGGF 139
Query: 688 VXRIPH-----IEVGDHIEK 732
+ + I+ GD IEK
Sbjct: 140 MDNVSKACGGLIQPGDQIEK 159
Score = 70.5 bits (165), Expect = 4e-11
Identities = 27/47 (57%), Positives = 36/47 (76%)
Frame = +2
Query: 371 FHCQQAHGSPLGLISGFSNVKELYEKIAECYEFSPEDILFCTLNTHK 511
F CQ AHGSP G+I GF V++L+ KI+EC++ +P I+FCT NTHK
Sbjct: 34 FFCQLAHGSPTGIIHGFRTVRQLHTKISECFDINPSQIMFCTRNTHK 80
>UniRef50_Q18488 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 357
Score = 66.1 bits (154), Expect = 8e-10
Identities = 29/59 (49%), Positives = 41/59 (69%)
Frame = +2
Query: 362 QLVFHCQQAHGSPLGLISGFSNVKELYEKIAECYEFSPEDILFCTLNTHKWI*KNFSEG 538
QL F CQ AHGSP+G+I ++N++ELY+ IA+C+ S +DI+F T+N K KN G
Sbjct: 62 QLKFACQMAHGSPVGIIDKWNNMEELYQSIADCFTISKDDIIFLTVNDFKPDMKNMFTG 120
Score = 64.9 bits (151), Expect = 2e-09
Identities = 34/82 (41%), Positives = 47/82 (57%), Gaps = 1/82 (1%)
Frame = +1
Query: 487 FLYFKYSQVDMKKLLGGQIGLEDFIFAHRKGRPKEIEIVKTEDALGLTITDNGAGYAFIK 666
FL + DMK + G + +D +FAH +G+ E+ +VK G+TITDNG G AFIK
Sbjct: 104 FLTVNDFKPDMKNMFTGTLNFKDMLFAHIRGQATELRVVKDAKNFGVTITDNGLGNAFIK 163
Query: 667 RIKEGSIVXRI-PHIEVGDHIE 729
I S+ R+ P +VG IE
Sbjct: 164 VISPDSVFDRMRPATQVGQLIE 185
>UniRef50_UPI0000F1F559 Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 1138
Score = 35.1 bits (77), Expect = 1.8
Identities = 16/48 (33%), Positives = 27/48 (56%)
Frame = +1
Query: 583 PKEIEIVKTEDALGLTITDNGAGYAFIKRIKEGSIVXRIPHIEVGDHI 726
P+ + I K + LG++I G F+ ++ EGSI + H+E GD +
Sbjct: 599 PRYVTIPKGAEPLGISIVGGDNGGIFVSKVTEGSIAQK-HHLEFGDQL 645
>UniRef50_Q4SG56 Cluster: Chromosome 17 SCAF14597, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 17
SCAF14597, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 964
Score = 34.7 bits (76), Expect = 2.4
Identities = 16/48 (33%), Positives = 27/48 (56%)
Frame = +1
Query: 583 PKEIEIVKTEDALGLTITDNGAGYAFIKRIKEGSIVXRIPHIEVGDHI 726
PKE + +G IT++G AFI ++K+GS+ + H+ GD +
Sbjct: 504 PKEAGAMLGLKVVGGRITESGRLGAFITKVKKGSLADVVGHLRAGDEV 551
>UniRef50_Q99NE5-4 Cluster: Isoform 4 of Q99NE5 ; n=6;
Tetrapoda|Rep: Isoform 4 of Q99NE5 - Mus musculus
(Mouse)
Length = 1374
Score = 33.9 bits (74), Expect = 4.2
Identities = 18/56 (32%), Positives = 28/56 (50%)
Frame = +1
Query: 559 IFAHRKGRPKEIEIVKTEDALGLTITDNGAGYAFIKRIKEGSIVXRIPHIEVGDHI 726
I R PKE + +G +TD G AFI ++K+GS+ + H+ GD +
Sbjct: 436 ILNKRTTMPKESGALLGLKVVGGKMTDLGRLGAFITKVKKGSLADVVGHLRAGDEV 491
>UniRef50_Q4SWT6 Cluster: Chromosome 11 SCAF13518, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 11
SCAF13518, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1178
Score = 33.9 bits (74), Expect = 4.2
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 4/52 (7%)
Frame = +1
Query: 583 PKEIEIVKTEDA-LGLTITD---NGAGYAFIKRIKEGSIVXRIPHIEVGDHI 726
P +EI+K+ A LG+T+T I RIK GS+V R + GDH+
Sbjct: 235 PLLVEIIKSPGATLGITLTSANHRNKQVIVIDRIKSGSVVDRCGALHTGDHL 286
>UniRef50_Q9JIR4 Cluster: Regulating synaptic membrane exocytosis
protein 1; n=13; Euteleostomi|Rep: Regulating synaptic
membrane exocytosis protein 1 - Rattus norvegicus (Rat)
Length = 1615
Score = 33.9 bits (74), Expect = 4.2
Identities = 18/56 (32%), Positives = 28/56 (50%)
Frame = +1
Query: 559 IFAHRKGRPKEIEIVKTEDALGLTITDNGAGYAFIKRIKEGSIVXRIPHIEVGDHI 726
I R PKE + +G +TD G AFI ++K+GS+ + H+ GD +
Sbjct: 615 ILNKRTTMPKESGALLGLKVVGGKMTDLGRLGAFITKVKKGSLADVVGHLRAGDEV 670
>UniRef50_Q99NE5 Cluster: Regulating synaptic membrane exocytosis
protein 1; n=11; Tetrapoda|Rep: Regulating synaptic
membrane exocytosis protein 1 - Mus musculus (Mouse)
Length = 1463
Score = 33.9 bits (74), Expect = 4.2
Identities = 18/56 (32%), Positives = 28/56 (50%)
Frame = +1
Query: 559 IFAHRKGRPKEIEIVKTEDALGLTITDNGAGYAFIKRIKEGSIVXRIPHIEVGDHI 726
I R PKE + +G +TD G AFI ++K+GS+ + H+ GD +
Sbjct: 436 ILNKRTTMPKESGALLGLKVVGGKMTDLGRLGAFITKVKKGSLADVVGHLRAGDEV 491
>UniRef50_P54936 Cluster: Protein lin-2; n=3; Caenorhabditis|Rep:
Protein lin-2 - Caenorhabditis elegans
Length = 961
Score = 33.9 bits (74), Expect = 4.2
Identities = 14/42 (33%), Positives = 24/42 (57%)
Frame = +1
Query: 607 TEDALGLTITDNGAGYAFIKRIKEGSIVXRIPHIEVGDHIEK 732
T++ +G+T+ N G F+ RI G ++ R + VGD I +
Sbjct: 553 TQEPMGITLKVNEDGRCFVARIMHGGMIHRQATLHVGDEIRE 594
>UniRef50_Q4JTP8 Cluster: Two-component system sensor kinase MtrB
precursor; n=1; Corynebacterium jeikeium K411|Rep:
Two-component system sensor kinase MtrB precursor -
Corynebacterium jeikeium (strain K411)
Length = 578
Score = 33.5 bits (73), Expect = 5.5
Identities = 12/28 (42%), Positives = 20/28 (71%)
Frame = +1
Query: 568 HRKGRPKEIEIVKTEDALGLTITDNGAG 651
H +G+P E+++ EDAL + +TD+G G
Sbjct: 457 HSEGKPIEVKMAVGEDALAVAVTDHGVG 484
>UniRef50_P48371 Cluster: DNA gyrase subunit A; n=456; cellular
organisms|Rep: DNA gyrase subunit A - Neisseria
gonorrhoeae
Length = 916
Score = 33.1 bits (72), Expect = 7.3
Identities = 27/101 (26%), Positives = 45/101 (44%)
Frame = +3
Query: 264 RLNTRRHRYHPHQ*KILNHSLLESIIATVRRSHNWSSTVSKLTEVHWASSLVSLTSKNYM 443
RL RH H + K + S ++ II ++ S N + KL WASSLV +
Sbjct: 378 RLKKARHEGHIAERKAVALSNIDEIIKLIKESPNAAEAKEKLLARPWASSLV---EEMLT 434
Query: 444 RR*QNVTNFHPKIFFSVL*ILTSGYEKTSRRANRIRRLYFR 566
R ++ P+ + + + GY + +A+ I R+ R
Sbjct: 435 RSGLDLEMMRPEGLVANIGLKKQGYYLSEIQADAILRMSLR 475
>UniRef50_A0BIK3 Cluster: Chromosome undetermined scaffold_11, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_11,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 352
Score = 32.7 bits (71), Expect = 9.6
Identities = 20/84 (23%), Positives = 41/84 (48%), Gaps = 4/84 (4%)
Frame = -3
Query: 261 FF*ITTXYKNTL*RQYFSFN----KNDSPRTFSTHVP*NFNHHKAAYLVKTLKYIAAS*H 94
+F I ++T + + S+N K+ ++ T+V NF +K YL K + + S
Sbjct: 198 YFKIEPKIQDTYRKSFISYNLIQSKSKLSKSCQTYVEQNFESNKQIYLQKLINNKSNSSK 257
Query: 93 KITYRPMAIFDDYIVMFSETVHIE 22
+ R +FDD +++ ++I+
Sbjct: 258 SMEKRIQQLFDDLKLVYQNNIYID 281
>UniRef50_Q8J2X1 Cluster: Putative uncharacterized protein; n=3;
Pyrococcus|Rep: Putative uncharacterized protein -
Pyrococcus abyssi
Length = 91
Score = 32.7 bits (71), Expect = 9.6
Identities = 26/75 (34%), Positives = 36/75 (48%)
Frame = +1
Query: 505 SQVDMKKLLGGQIGLEDFIFAHRKGRPKEIEIVKTEDALGLTITDNGAGYAFIKRIKEGS 684
S +D+ ++ GG+ G F KGR E VK + + I G G I RIK
Sbjct: 5 SWMDVLEMYGGKGGKRKF--TGDKGRRMEAP-VKVGERYKVKIESMGKGGDGIARIK--G 59
Query: 685 IVXRIPHIEVGDHIE 729
V +PH +VGD +E
Sbjct: 60 FVIFVPHTKVGDEVE 74
>UniRef50_Q86UR5 Cluster: Regulating synaptic membrane exocytosis
protein 1; n=62; Euteleostomi|Rep: Regulating synaptic
membrane exocytosis protein 1 - Homo sapiens (Human)
Length = 1692
Score = 32.7 bits (71), Expect = 9.6
Identities = 17/56 (30%), Positives = 28/56 (50%)
Frame = +1
Query: 559 IFAHRKGRPKEIEIVKTEDALGLTITDNGAGYAFIKRIKEGSIVXRIPHIEVGDHI 726
I R PK+ + +G +TD G AFI ++K+GS+ + H+ GD +
Sbjct: 601 ILNKRTTMPKDSGALLGLKVVGGKMTDLGRLGAFITKVKKGSLADVVGHLRAGDEV 656
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 673,418,750
Number of Sequences: 1657284
Number of extensions: 13028909
Number of successful extensions: 29288
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 28479
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 29283
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 59677054775
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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