Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= NRPG1114
(653 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X59618-1|CAA42181.1| 389|Homo sapiens small subunit ribonucleot... 237 2e-62
S40301-1|AAA09577.1| 389|Homo sapiens ribonucleotide reductase ... 237 2e-62
BC030154-1|AAH30154.1| 389|Homo sapiens ribonucleotide reductas... 237 2e-62
BC001886-1|AAH01886.1| 389|Homo sapiens ribonucleotide reductas... 237 2e-62
AY032750-1|AAK51163.1| 389|Homo sapiens ribonucleotide reductas... 237 2e-62
AC104794-2|AAX93099.1| 389|Homo sapiens unknown protein. 237 2e-62
DQ027001-1|AAY29059.1| 351|Homo sapiens ribonucleotide reductas... 221 2e-57
BC130628-1|AAI30629.1| 351|Homo sapiens ribonucleotide reductas... 221 2e-57
BC117496-1|AAI17497.1| 351|Homo sapiens ribonucleotide reductas... 221 2e-57
BC108261-1|AAI08262.1| 351|Homo sapiens ribonucleotide reductas... 221 2e-57
AK001965-1|BAA92005.1| 351|Homo sapiens protein ( Homo sapiens ... 221 2e-57
AB166671-1|BAD12267.1| 351|Homo sapiens p53-inducible ribonucle... 221 2e-57
AB036532-1|BAA92493.1| 351|Homo sapiens ribonucleotide reductas... 221 2e-57
AB036063-1|BAA92434.1| 351|Homo sapiens ribonucleotide reductas... 221 2e-57
AB163437-1|BAD11774.1| 299|Homo sapiens p53-inducible ribonucle... 156 7e-38
BC042468-1|AAH42468.1| 285|Homo sapiens Similar to ribonucleoti... 155 1e-37
BC028932-1|AAH28932.1| 172|Homo sapiens Similar to ribonucleoti... 139 7e-33
AB166670-1|BAD12266.1| 139|Homo sapiens p53-inducible ribonucle... 139 7e-33
BC068260-1|AAH68260.1| 601|Homo sapiens PRODH protein protein. 34 0.39
U82381-1|AAB88789.1| 516|Homo sapiens proline dehydrogenase/pro... 33 0.89
BC121809-1|AAI21810.1| 492|Homo sapiens PRODH protein protein. 33 0.89
BC118597-1|AAI18598.1| 492|Homo sapiens PRODH protein protein. 33 0.89
BC094736-1|AAH94736.1| 544|Homo sapiens PRODH protein protein. 33 0.89
AF120278-1|AAD24775.1| 516|Homo sapiens proline dehydrogenase p... 33 0.89
U79754-1|AAF21464.1| 600|Homo sapiens proline oxidase 2 protein. 30 6.3
AB166669-1|BAD12265.1| 66|Homo sapiens p53-inducible ribonucle... 30 6.3
>X59618-1|CAA42181.1| 389|Homo sapiens small subunit ribonucleotide
reductase protein.
Length = 389
Score = 237 bits (581), Expect = 2e-62
Identities = 107/124 (86%), Positives = 116/124 (93%)
Frame = +3
Query: 3 QKEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDLSDWETLKDSERHFI 182
+ EPLLRENPRRFVIFPI+Y DIWQMYKKAEASFWT EEVDLSKD+ WE+LK ER+FI
Sbjct: 68 EDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLKPEERYFI 127
Query: 183 KHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIRDP 362
HVLAFFAASDGIVNENLVERFSQEVQ+TEARCFYGFQIAMEN+HSEMYSLLIDTYI+DP
Sbjct: 128 SHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKDP 187
Query: 363 KERD 374
KER+
Sbjct: 188 KERE 191
Score = 139 bits (337), Expect = 7e-33
Identities = 67/103 (65%), Positives = 81/103 (78%)
Frame = +3
Query: 345 TYIRDPKERDEGLHTDFACLMFQHLVQKPTKECVLHIIKDAVVIEQEFLTDALPVRLLGM 524
T+ + RDEGLH DFACLMF+HLV KP++E V II +AV IEQEFLT+ALPV+L+GM
Sbjct: 256 TFSNELISRDEGLHCDFACLMFKHLVHKPSEERVREIIINAVRIEQEFLTEALPVKLIGM 315
Query: 525 NCELMSQYIEFVADRLLVDLIGEKHYNTKNPFDFMNLISLEGK 653
NC LM QYIEFVADRL+++L K + +NPFDFM ISLEGK
Sbjct: 316 NCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFMENISLEGK 358
>S40301-1|AAA09577.1| 389|Homo sapiens ribonucleotide reductase R2
subunit protein.
Length = 389
Score = 237 bits (581), Expect = 2e-62
Identities = 107/124 (86%), Positives = 116/124 (93%)
Frame = +3
Query: 3 QKEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDLSDWETLKDSERHFI 182
+ EPLLRENPRRFVIFPI+Y DIWQMYKKAEASFWT EEVDLSKD+ WE+LK ER+FI
Sbjct: 68 EDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLKPEERYFI 127
Query: 183 KHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIRDP 362
HVLAFFAASDGIVNENLVERFSQEVQ+TEARCFYGFQIAMEN+HSEMYSLLIDTYI+DP
Sbjct: 128 SHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKDP 187
Query: 363 KERD 374
KER+
Sbjct: 188 KERE 191
Score = 139 bits (337), Expect = 7e-33
Identities = 67/103 (65%), Positives = 81/103 (78%)
Frame = +3
Query: 345 TYIRDPKERDEGLHTDFACLMFQHLVQKPTKECVLHIIKDAVVIEQEFLTDALPVRLLGM 524
T+ + RDEGLH DFACLMF+HLV KP++E V II +AV IEQEFLT+ALPV+L+GM
Sbjct: 256 TFSNELISRDEGLHCDFACLMFKHLVHKPSEERVREIIINAVRIEQEFLTEALPVKLIGM 315
Query: 525 NCELMSQYIEFVADRLLVDLIGEKHYNTKNPFDFMNLISLEGK 653
NC LM QYIEFVADRL+++L K + +NPFDFM ISLEGK
Sbjct: 316 NCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFMENISLEGK 358
>BC030154-1|AAH30154.1| 389|Homo sapiens ribonucleotide reductase
M2 polypeptide protein.
Length = 389
Score = 237 bits (581), Expect = 2e-62
Identities = 107/124 (86%), Positives = 116/124 (93%)
Frame = +3
Query: 3 QKEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDLSDWETLKDSERHFI 182
+ EPLLRENPRRFVIFPI+Y DIWQMYKKAEASFWT EEVDLSKD+ WE+LK ER+FI
Sbjct: 68 EDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLKPEERYFI 127
Query: 183 KHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIRDP 362
HVLAFFAASDGIVNENLVERFSQEVQ+TEARCFYGFQIAMEN+HSEMYSLLIDTYI+DP
Sbjct: 128 SHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKDP 187
Query: 363 KERD 374
KER+
Sbjct: 188 KERE 191
Score = 139 bits (337), Expect = 7e-33
Identities = 67/103 (65%), Positives = 81/103 (78%)
Frame = +3
Query: 345 TYIRDPKERDEGLHTDFACLMFQHLVQKPTKECVLHIIKDAVVIEQEFLTDALPVRLLGM 524
T+ + RDEGLH DFACLMF+HLV KP++E V II +AV IEQEFLT+ALPV+L+GM
Sbjct: 256 TFSNELISRDEGLHCDFACLMFKHLVHKPSEERVREIIINAVRIEQEFLTEALPVKLIGM 315
Query: 525 NCELMSQYIEFVADRLLVDLIGEKHYNTKNPFDFMNLISLEGK 653
NC LM QYIEFVADRL+++L K + +NPFDFM ISLEGK
Sbjct: 316 NCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFMENISLEGK 358
>BC001886-1|AAH01886.1| 389|Homo sapiens ribonucleotide reductase
M2 polypeptide protein.
Length = 389
Score = 237 bits (581), Expect = 2e-62
Identities = 107/124 (86%), Positives = 116/124 (93%)
Frame = +3
Query: 3 QKEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDLSDWETLKDSERHFI 182
+ EPLLRENPRRFVIFPI+Y DIWQMYKKAEASFWT EEVDLSKD+ WE+LK ER+FI
Sbjct: 68 EDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLKPEERYFI 127
Query: 183 KHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIRDP 362
HVLAFFAASDGIVNENLVERFSQEVQ+TEARCFYGFQIAMEN+HSEMYSLLIDTYI+DP
Sbjct: 128 SHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKDP 187
Query: 363 KERD 374
KER+
Sbjct: 188 KERE 191
Score = 139 bits (337), Expect = 7e-33
Identities = 67/103 (65%), Positives = 81/103 (78%)
Frame = +3
Query: 345 TYIRDPKERDEGLHTDFACLMFQHLVQKPTKECVLHIIKDAVVIEQEFLTDALPVRLLGM 524
T+ + RDEGLH DFACLMF+HLV KP++E V II +AV IEQEFLT+ALPV+L+GM
Sbjct: 256 TFSNELISRDEGLHCDFACLMFKHLVHKPSEERVREIIINAVRIEQEFLTEALPVKLIGM 315
Query: 525 NCELMSQYIEFVADRLLVDLIGEKHYNTKNPFDFMNLISLEGK 653
NC LM QYIEFVADRL+++L K + +NPFDFM ISLEGK
Sbjct: 316 NCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFMENISLEGK 358
>AY032750-1|AAK51163.1| 389|Homo sapiens ribonucleotide reductase
M2 subunit protein.
Length = 389
Score = 237 bits (581), Expect = 2e-62
Identities = 107/124 (86%), Positives = 116/124 (93%)
Frame = +3
Query: 3 QKEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDLSDWETLKDSERHFI 182
+ EPLLRENPRRFVIFPI+Y DIWQMYKKAEASFWT EEVDLSKD+ WE+LK ER+FI
Sbjct: 68 EDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLKPEERYFI 127
Query: 183 KHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIRDP 362
HVLAFFAASDGIVNENLVERFSQEVQ+TEARCFYGFQIAMEN+HSEMYSLLIDTYI+DP
Sbjct: 128 SHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKDP 187
Query: 363 KERD 374
KER+
Sbjct: 188 KERE 191
Score = 139 bits (337), Expect = 7e-33
Identities = 67/103 (65%), Positives = 81/103 (78%)
Frame = +3
Query: 345 TYIRDPKERDEGLHTDFACLMFQHLVQKPTKECVLHIIKDAVVIEQEFLTDALPVRLLGM 524
T+ + RDEGLH DFACLMF+HLV KP++E V II +AV IEQEFLT+ALPV+L+GM
Sbjct: 256 TFSNELISRDEGLHCDFACLMFKHLVHKPSEERVREIIINAVRIEQEFLTEALPVKLIGM 315
Query: 525 NCELMSQYIEFVADRLLVDLIGEKHYNTKNPFDFMNLISLEGK 653
NC LM QYIEFVADRL+++L K + +NPFDFM ISLEGK
Sbjct: 316 NCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFMENISLEGK 358
>AC104794-2|AAX93099.1| 389|Homo sapiens unknown protein.
Length = 389
Score = 237 bits (581), Expect = 2e-62
Identities = 107/124 (86%), Positives = 116/124 (93%)
Frame = +3
Query: 3 QKEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDLSDWETLKDSERHFI 182
+ EPLLRENPRRFVIFPI+Y DIWQMYKKAEASFWT EEVDLSKD+ WE+LK ER+FI
Sbjct: 68 EDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLKPEERYFI 127
Query: 183 KHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIRDP 362
HVLAFFAASDGIVNENLVERFSQEVQ+TEARCFYGFQIAMEN+HSEMYSLLIDTYI+DP
Sbjct: 128 SHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKDP 187
Query: 363 KERD 374
KER+
Sbjct: 188 KERE 191
Score = 139 bits (337), Expect = 7e-33
Identities = 67/103 (65%), Positives = 81/103 (78%)
Frame = +3
Query: 345 TYIRDPKERDEGLHTDFACLMFQHLVQKPTKECVLHIIKDAVVIEQEFLTDALPVRLLGM 524
T+ + RDEGLH DFACLMF+HLV KP++E V II +AV IEQEFLT+ALPV+L+GM
Sbjct: 256 TFSNELISRDEGLHCDFACLMFKHLVHKPSEERVREIIINAVRIEQEFLTEALPVKLIGM 315
Query: 525 NCELMSQYIEFVADRLLVDLIGEKHYNTKNPFDFMNLISLEGK 653
NC LM QYIEFVADRL+++L K + +NPFDFM ISLEGK
Sbjct: 316 NCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFMENISLEGK 358
>DQ027001-1|AAY29059.1| 351|Homo sapiens ribonucleotide reductase
M2 B (TP53 inducible) protein.
Length = 351
Score = 221 bits (540), Expect = 2e-57
Identities = 100/123 (81%), Positives = 112/123 (91%)
Frame = +3
Query: 6 KEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDLSDWETLKDSERHFIK 185
+EPLLR++ RRFVIFPIQYPDIW+MYK+A+ASFWT EEVDLSKDL W LK E++FI
Sbjct: 31 EEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPHWNKLKADEKYFIS 90
Query: 186 HVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIRDPK 365
H+LAFFAASDGIVNENLVERFSQEVQV EARCFYGFQI +ENVHSEMYSLLIDTYIRDPK
Sbjct: 91 HILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPK 150
Query: 366 ERD 374
+R+
Sbjct: 151 KRE 153
Score = 141 bits (341), Expect = 2e-33
Identities = 70/103 (67%), Positives = 80/103 (77%)
Frame = +3
Query: 345 TYIRDPKERDEGLHTDFACLMFQHLVQKPTKECVLHIIKDAVVIEQEFLTDALPVRLLGM 524
T+ + RDEGLH DFACLMFQ+LV KP++E V II DAV IEQEFLT+ALPV L+GM
Sbjct: 218 TFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLTEALPVGLIGM 277
Query: 525 NCELMSQYIEFVADRLLVDLIGEKHYNTKNPFDFMNLISLEGK 653
NC LM QYIEFVADRLLV+L K + +NPFDFM ISLEGK
Sbjct: 278 NCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISLEGK 320
>BC130628-1|AAI30629.1| 351|Homo sapiens ribonucleotide reductase
M2 B (TP53 inducible) protein.
Length = 351
Score = 221 bits (540), Expect = 2e-57
Identities = 100/123 (81%), Positives = 112/123 (91%)
Frame = +3
Query: 6 KEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDLSDWETLKDSERHFIK 185
+EPLLR++ RRFVIFPIQYPDIW+MYK+A+ASFWT EEVDLSKDL W LK E++FI
Sbjct: 31 EEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPHWNKLKADEKYFIS 90
Query: 186 HVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIRDPK 365
H+LAFFAASDGIVNENLVERFSQEVQV EARCFYGFQI +ENVHSEMYSLLIDTYIRDPK
Sbjct: 91 HILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPK 150
Query: 366 ERD 374
+R+
Sbjct: 151 KRE 153
Score = 141 bits (341), Expect = 2e-33
Identities = 70/103 (67%), Positives = 80/103 (77%)
Frame = +3
Query: 345 TYIRDPKERDEGLHTDFACLMFQHLVQKPTKECVLHIIKDAVVIEQEFLTDALPVRLLGM 524
T+ + RDEGLH DFACLMFQ+LV KP++E V II DAV IEQEFLT+ALPV L+GM
Sbjct: 218 TFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLTEALPVGLIGM 277
Query: 525 NCELMSQYIEFVADRLLVDLIGEKHYNTKNPFDFMNLISLEGK 653
NC LM QYIEFVADRLLV+L K + +NPFDFM ISLEGK
Sbjct: 278 NCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISLEGK 320
>BC117496-1|AAI17497.1| 351|Homo sapiens ribonucleotide reductase
M2 B (TP53 inducible) protein.
Length = 351
Score = 221 bits (540), Expect = 2e-57
Identities = 100/123 (81%), Positives = 112/123 (91%)
Frame = +3
Query: 6 KEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDLSDWETLKDSERHFIK 185
+EPLLR++ RRFVIFPIQYPDIW+MYK+A+ASFWT EEVDLSKDL W LK E++FI
Sbjct: 31 EEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPHWNKLKADEKYFIS 90
Query: 186 HVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIRDPK 365
H+LAFFAASDGIVNENLVERFSQEVQV EARCFYGFQI +ENVHSEMYSLLIDTYIRDPK
Sbjct: 91 HILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPK 150
Query: 366 ERD 374
+R+
Sbjct: 151 KRE 153
Score = 141 bits (341), Expect = 2e-33
Identities = 70/103 (67%), Positives = 80/103 (77%)
Frame = +3
Query: 345 TYIRDPKERDEGLHTDFACLMFQHLVQKPTKECVLHIIKDAVVIEQEFLTDALPVRLLGM 524
T+ + RDEGLH DFACLMFQ+LV KP++E V II DAV IEQEFLT+ALPV L+GM
Sbjct: 218 TFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLTEALPVGLIGM 277
Query: 525 NCELMSQYIEFVADRLLVDLIGEKHYNTKNPFDFMNLISLEGK 653
NC LM QYIEFVADRLLV+L K + +NPFDFM ISLEGK
Sbjct: 278 NCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISLEGK 320
>BC108261-1|AAI08262.1| 351|Homo sapiens ribonucleotide reductase
M2 B (TP53 inducible) protein.
Length = 351
Score = 221 bits (540), Expect = 2e-57
Identities = 100/123 (81%), Positives = 112/123 (91%)
Frame = +3
Query: 6 KEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDLSDWETLKDSERHFIK 185
+EPLLR++ RRFVIFPIQYPDIW+MYK+A+ASFWT EEVDLSKDL W LK E++FI
Sbjct: 31 EEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPHWNKLKADEKYFIS 90
Query: 186 HVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIRDPK 365
H+LAFFAASDGIVNENLVERFSQEVQV EARCFYGFQI +ENVHSEMYSLLIDTYIRDPK
Sbjct: 91 HILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPK 150
Query: 366 ERD 374
+R+
Sbjct: 151 KRE 153
Score = 141 bits (341), Expect = 2e-33
Identities = 70/103 (67%), Positives = 80/103 (77%)
Frame = +3
Query: 345 TYIRDPKERDEGLHTDFACLMFQHLVQKPTKECVLHIIKDAVVIEQEFLTDALPVRLLGM 524
T+ + RDEGLH DFACLMFQ+LV KP++E V II DAV IEQEFLT+ALPV L+GM
Sbjct: 218 TFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLTEALPVGLIGM 277
Query: 525 NCELMSQYIEFVADRLLVDLIGEKHYNTKNPFDFMNLISLEGK 653
NC LM QYIEFVADRLLV+L K + +NPFDFM ISLEGK
Sbjct: 278 NCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISLEGK 320
>AK001965-1|BAA92005.1| 351|Homo sapiens protein ( Homo sapiens
cDNA FLJ11103 fis, clone PLACE1005656, highly similar to
RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE M2 CHAIN (EC
1.17.4.1). ).
Length = 351
Score = 221 bits (540), Expect = 2e-57
Identities = 100/123 (81%), Positives = 112/123 (91%)
Frame = +3
Query: 6 KEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDLSDWETLKDSERHFIK 185
+EPLLR++ RRFVIFPIQYPDIW+MYK+A+ASFWT EEVDLSKDL W LK E++FI
Sbjct: 31 EEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPHWNKLKADEKYFIS 90
Query: 186 HVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIRDPK 365
H+LAFFAASDGIVNENLVERFSQEVQV EARCFYGFQI +ENVHSEMYSLLIDTYIRDPK
Sbjct: 91 HILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPK 150
Query: 366 ERD 374
+R+
Sbjct: 151 KRE 153
Score = 139 bits (337), Expect = 7e-33
Identities = 69/103 (66%), Positives = 80/103 (77%)
Frame = +3
Query: 345 TYIRDPKERDEGLHTDFACLMFQHLVQKPTKECVLHIIKDAVVIEQEFLTDALPVRLLGM 524
T+ + RDEGLH DFACLMFQ+LV KP++E V II DAV IEQEFLT+ALPV L+G+
Sbjct: 218 TFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLTEALPVGLIGV 277
Query: 525 NCELMSQYIEFVADRLLVDLIGEKHYNTKNPFDFMNLISLEGK 653
NC LM QYIEFVADRLLV+L K + +NPFDFM ISLEGK
Sbjct: 278 NCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISLEGK 320
>AB166671-1|BAD12267.1| 351|Homo sapiens p53-inducible
ribonucleotide reductase small subunit 2 protein.
Length = 351
Score = 221 bits (540), Expect = 2e-57
Identities = 100/123 (81%), Positives = 112/123 (91%)
Frame = +3
Query: 6 KEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDLSDWETLKDSERHFIK 185
+EPLLR++ RRFVIFPIQYPDIW+MYK+A+ASFWT EEVDLSKDL W LK E++FI
Sbjct: 31 EEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPHWNKLKADEKYFIS 90
Query: 186 HVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIRDPK 365
H+LAFFAASDGIVNENLVERFSQEVQV EARCFYGFQI +ENVHSEMYSLLIDTYIRDPK
Sbjct: 91 HILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPK 150
Query: 366 ERD 374
+R+
Sbjct: 151 KRE 153
Score = 141 bits (341), Expect = 2e-33
Identities = 70/103 (67%), Positives = 80/103 (77%)
Frame = +3
Query: 345 TYIRDPKERDEGLHTDFACLMFQHLVQKPTKECVLHIIKDAVVIEQEFLTDALPVRLLGM 524
T+ + RDEGLH DFACLMFQ+LV KP++E V II DAV IEQEFLT+ALPV L+GM
Sbjct: 218 TFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLTEALPVGLIGM 277
Query: 525 NCELMSQYIEFVADRLLVDLIGEKHYNTKNPFDFMNLISLEGK 653
NC LM QYIEFVADRLLV+L K + +NPFDFM ISLEGK
Sbjct: 278 NCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISLEGK 320
>AB036532-1|BAA92493.1| 351|Homo sapiens ribonucleotide reductase
protein.
Length = 351
Score = 221 bits (540), Expect = 2e-57
Identities = 100/123 (81%), Positives = 112/123 (91%)
Frame = +3
Query: 6 KEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDLSDWETLKDSERHFIK 185
+EPLLR++ RRFVIFPIQYPDIW+MYK+A+ASFWT EEVDLSKDL W LK E++FI
Sbjct: 31 EEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPHWNKLKADEKYFIS 90
Query: 186 HVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIRDPK 365
H+LAFFAASDGIVNENLVERFSQEVQV EARCFYGFQI +ENVHSEMYSLLIDTYIRDPK
Sbjct: 91 HILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPK 150
Query: 366 ERD 374
+R+
Sbjct: 151 KRE 153
Score = 141 bits (341), Expect = 2e-33
Identities = 70/103 (67%), Positives = 80/103 (77%)
Frame = +3
Query: 345 TYIRDPKERDEGLHTDFACLMFQHLVQKPTKECVLHIIKDAVVIEQEFLTDALPVRLLGM 524
T+ + RDEGLH DFACLMFQ+LV KP++E V II DAV IEQEFLT+ALPV L+GM
Sbjct: 218 TFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLTEALPVGLIGM 277
Query: 525 NCELMSQYIEFVADRLLVDLIGEKHYNTKNPFDFMNLISLEGK 653
NC LM QYIEFVADRLLV+L K + +NPFDFM ISLEGK
Sbjct: 278 NCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISLEGK 320
>AB036063-1|BAA92434.1| 351|Homo sapiens ribonucleotide reductase
protein.
Length = 351
Score = 221 bits (540), Expect = 2e-57
Identities = 100/123 (81%), Positives = 112/123 (91%)
Frame = +3
Query: 6 KEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDLSDWETLKDSERHFIK 185
+EPLLR++ RRFVIFPIQYPDIW+MYK+A+ASFWT EEVDLSKDL W LK E++FI
Sbjct: 31 EEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPHWNKLKADEKYFIS 90
Query: 186 HVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIRDPK 365
H+LAFFAASDGIVNENLVERFSQEVQV EARCFYGFQI +ENVHSEMYSLLIDTYIRDPK
Sbjct: 91 HILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPK 150
Query: 366 ERD 374
+R+
Sbjct: 151 KRE 153
Score = 141 bits (341), Expect = 2e-33
Identities = 70/103 (67%), Positives = 80/103 (77%)
Frame = +3
Query: 345 TYIRDPKERDEGLHTDFACLMFQHLVQKPTKECVLHIIKDAVVIEQEFLTDALPVRLLGM 524
T+ + RDEGLH DFACLMFQ+LV KP++E V II DAV IEQEFLT+ALPV L+GM
Sbjct: 218 TFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLTEALPVGLIGM 277
Query: 525 NCELMSQYIEFVADRLLVDLIGEKHYNTKNPFDFMNLISLEGK 653
NC LM QYIEFVADRLLV+L K + +NPFDFM ISLEGK
Sbjct: 278 NCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISLEGK 320
>AB163437-1|BAD11774.1| 299|Homo sapiens p53-inducible
ribonucleotide reductase small subunit 2 long form
protein.
Length = 299
Score = 156 bits (378), Expect = 7e-38
Identities = 73/97 (75%), Positives = 83/97 (85%)
Frame = +3
Query: 84 KKAEASFWTVEEVDLSKDLSDWETLKDSERHFIKHVLAFFAASDGIVNENLVERFSQEVQ 263
++ EA+ +EVDLSKDL W LK E++FI H+LAFFAASDGIVNENLVERFSQEVQ
Sbjct: 5 ERPEAAGLDQDEVDLSKDLPHWNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQ 64
Query: 264 VTEARCFYGFQIAMENVHSEMYSLLIDTYIRDPKERD 374
V EARCFYGFQI +ENVHSEMYSLLIDTYIRDPK+R+
Sbjct: 65 VPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKRE 101
Score = 141 bits (341), Expect = 2e-33
Identities = 70/103 (67%), Positives = 80/103 (77%)
Frame = +3
Query: 345 TYIRDPKERDEGLHTDFACLMFQHLVQKPTKECVLHIIKDAVVIEQEFLTDALPVRLLGM 524
T+ + RDEGLH DFACLMFQ+LV KP++E V II DAV IEQEFLT+ALPV L+GM
Sbjct: 166 TFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLTEALPVGLIGM 225
Query: 525 NCELMSQYIEFVADRLLVDLIGEKHYNTKNPFDFMNLISLEGK 653
NC LM QYIEFVADRLLV+L K + +NPFDFM ISLEGK
Sbjct: 226 NCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISLEGK 268
>BC042468-1|AAH42468.1| 285|Homo sapiens Similar to ribonucleotide
reductase M2 polypeptide protein.
Length = 285
Score = 155 bits (377), Expect = 1e-37
Identities = 72/87 (82%), Positives = 78/87 (89%)
Frame = +3
Query: 114 EEVDLSKDLSDWETLKDSERHFIKHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGF 293
EEVDLSKDL W LK E++FI H+LAFFAASDGIVNENLVERFSQEVQV EARCFYGF
Sbjct: 1 EEVDLSKDLPHWNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGF 60
Query: 294 QIAMENVHSEMYSLLIDTYIRDPKERD 374
QI +ENVHSEMYSLLIDTYIRDPK+R+
Sbjct: 61 QILIENVHSEMYSLLIDTYIRDPKKRE 87
Score = 141 bits (341), Expect = 2e-33
Identities = 70/103 (67%), Positives = 80/103 (77%)
Frame = +3
Query: 345 TYIRDPKERDEGLHTDFACLMFQHLVQKPTKECVLHIIKDAVVIEQEFLTDALPVRLLGM 524
T+ + RDEGLH DFACLMFQ+LV KP++E V II DAV IEQEFLT+ALPV L+GM
Sbjct: 152 TFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLTEALPVGLIGM 211
Query: 525 NCELMSQYIEFVADRLLVDLIGEKHYNTKNPFDFMNLISLEGK 653
NC LM QYIEFVADRLLV+L K + +NPFDFM ISLEGK
Sbjct: 212 NCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISLEGK 254
>BC028932-1|AAH28932.1| 172|Homo sapiens Similar to ribonucleotide
reductase protein r2 class I protein.
Length = 172
Score = 139 bits (337), Expect = 7e-33
Identities = 67/103 (65%), Positives = 81/103 (78%)
Frame = +3
Query: 345 TYIRDPKERDEGLHTDFACLMFQHLVQKPTKECVLHIIKDAVVIEQEFLTDALPVRLLGM 524
T+ + RDEGLH DFACLMF+HLV KP++E V II +AV IEQEFLT+ALPV+L+GM
Sbjct: 39 TFSNELISRDEGLHCDFACLMFKHLVHKPSEERVREIIINAVRIEQEFLTEALPVKLIGM 98
Query: 525 NCELMSQYIEFVADRLLVDLIGEKHYNTKNPFDFMNLISLEGK 653
NC LM QYIEFVADRL+++L K + +NPFDFM ISLEGK
Sbjct: 99 NCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFMENISLEGK 141
>AB166670-1|BAD12266.1| 139|Homo sapiens p53-inducible
ribonucleotide reductase small subunit 2 short form
gamma protein.
Length = 139
Score = 139 bits (337), Expect = 7e-33
Identities = 68/96 (70%), Positives = 78/96 (81%)
Frame = +3
Query: 366 ERDEGLHTDFACLMFQHLVQKPTKECVLHIIKDAVVIEQEFLTDALPVRLLGMNCELMSQ 545
++DEGLH DFACLMFQ+LV KP++E V II DAV IEQEFLT+ALPV L+GMNC LM Q
Sbjct: 13 DQDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLTEALPVGLIGMNCILMKQ 72
Query: 546 YIEFVADRLLVDLIGEKHYNTKNPFDFMNLISLEGK 653
YIEFVADRLLV+L K + +NPFDFM ISLEGK
Sbjct: 73 YIEFVADRLLVELGFSKVFQAENPFDFMENISLEGK 108
>BC068260-1|AAH68260.1| 601|Homo sapiens PRODH protein protein.
Length = 601
Score = 34.3 bits (75), Expect = 0.39
Identities = 24/89 (26%), Positives = 42/89 (47%), Gaps = 3/89 (3%)
Frame = +3
Query: 87 KAEASFW-TVEEVDLS--KDLSDWETLKDSERHFIKHVLAFFAASDGIVNENLVERFSQE 257
+AE W T E + +S DL DW +L DS KH++ A + + E+L+ RF++E
Sbjct: 295 RAEIEDWFTAETLGVSGTMDLLDWSSLIDSRTKLSKHLVVPNAQTGQL--EHLLSRFTEE 352
Query: 258 VQVTEARCFYGFQIAMENVHSEMYSLLID 344
++ R + + L++D
Sbjct: 353 EELQMTRMLQRMDVLAKKATEMGVRLMVD 381
>U82381-1|AAB88789.1| 516|Homo sapiens proline
dehydrogenase/proline oxidase protein.
Length = 516
Score = 33.1 bits (72), Expect = 0.89
Identities = 24/89 (26%), Positives = 41/89 (46%), Gaps = 3/89 (3%)
Frame = +3
Query: 87 KAEASFW-TVEEVDLS--KDLSDWETLKDSERHFIKHVLAFFAASDGIVNENLVERFSQE 257
+AE W T E + +S DL DW +L DS KH++ A + + E L+ RF++E
Sbjct: 210 RAEIEDWFTAETLGVSGTMDLLDWSSLIDSRTKLSKHLVVPNAQTGQL--EPLLSRFTEE 267
Query: 258 VQVTEARCFYGFQIAMENVHSEMYSLLID 344
++ R + + L++D
Sbjct: 268 EELQMTRMLQRMDVLAKKATEMGVRLMVD 296
>BC121809-1|AAI21810.1| 492|Homo sapiens PRODH protein protein.
Length = 492
Score = 33.1 bits (72), Expect = 0.89
Identities = 24/89 (26%), Positives = 41/89 (46%), Gaps = 3/89 (3%)
Frame = +3
Query: 87 KAEASFW-TVEEVDLS--KDLSDWETLKDSERHFIKHVLAFFAASDGIVNENLVERFSQE 257
+AE W T E + +S DL DW +L DS KH++ A + + E L+ RF++E
Sbjct: 186 RAEIEDWFTAETLGVSGTMDLLDWSSLIDSRTKLSKHLVVPNAQTGQL--EPLLSRFTEE 243
Query: 258 VQVTEARCFYGFQIAMENVHSEMYSLLID 344
++ R + + L++D
Sbjct: 244 EELQMTRMLQRMDVLAKKATEMGVRLMVD 272
>BC118597-1|AAI18598.1| 492|Homo sapiens PRODH protein protein.
Length = 492
Score = 33.1 bits (72), Expect = 0.89
Identities = 24/89 (26%), Positives = 41/89 (46%), Gaps = 3/89 (3%)
Frame = +3
Query: 87 KAEASFW-TVEEVDLS--KDLSDWETLKDSERHFIKHVLAFFAASDGIVNENLVERFSQE 257
+AE W T E + +S DL DW +L DS KH++ A + + E L+ RF++E
Sbjct: 186 RAEIEDWFTAETLGVSGTMDLLDWSSLIDSRTKLSKHLVVPNAQTGQL--EPLLSRFTEE 243
Query: 258 VQVTEARCFYGFQIAMENVHSEMYSLLID 344
++ R + + L++D
Sbjct: 244 EELQMTRMLQRMDVLAKKATEMGVRLMVD 272
>BC094736-1|AAH94736.1| 544|Homo sapiens PRODH protein protein.
Length = 544
Score = 33.1 bits (72), Expect = 0.89
Identities = 24/89 (26%), Positives = 41/89 (46%), Gaps = 3/89 (3%)
Frame = +3
Query: 87 KAEASFW-TVEEVDLS--KDLSDWETLKDSERHFIKHVLAFFAASDGIVNENLVERFSQE 257
+AE W T E + +S DL DW +L DS KH++ A + + E L+ RF++E
Sbjct: 238 RAEIEDWFTAETLGVSGTMDLLDWSSLIDSRTKLSKHLVVPNAQTGQL--EPLLSRFTEE 295
Query: 258 VQVTEARCFYGFQIAMENVHSEMYSLLID 344
++ R + + L++D
Sbjct: 296 EELQMTRMLQRMDVLAKKATEMGVRLMVD 324
>AF120278-1|AAD24775.1| 516|Homo sapiens proline dehydrogenase
protein.
Length = 516
Score = 33.1 bits (72), Expect = 0.89
Identities = 24/89 (26%), Positives = 41/89 (46%), Gaps = 3/89 (3%)
Frame = +3
Query: 87 KAEASFW-TVEEVDLS--KDLSDWETLKDSERHFIKHVLAFFAASDGIVNENLVERFSQE 257
+AE W T E + +S DL DW +L DS KH++ A + + E L+ RF++E
Sbjct: 210 RAEIEDWFTAETLGVSGTMDLLDWSSLIDSRTKLSKHLVVPNAQTGQL--EPLLSRFTEE 267
Query: 258 VQVTEARCFYGFQIAMENVHSEMYSLLID 344
++ R + + L++D
Sbjct: 268 EELQMTRMLQRMDVLAKKATEMGVRLMVD 296
>U79754-1|AAF21464.1| 600|Homo sapiens proline oxidase 2 protein.
Length = 600
Score = 30.3 bits (65), Expect = 6.3
Identities = 23/89 (25%), Positives = 40/89 (44%), Gaps = 3/89 (3%)
Frame = +3
Query: 87 KAEASFW-TVEEVDLS--KDLSDWETLKDSERHFIKHVLAFFAASDGIVNENLVERFSQE 257
+AE W T E + +S DL DW +L DS KH++ A + + E L+ F++E
Sbjct: 294 RAEIEDWFTAETLGVSGTMDLLDWSSLIDSRTKLSKHLVVPNAQTGQL--EPLLSGFTEE 351
Query: 258 VQVTEARCFYGFQIAMENVHSEMYSLLID 344
++ R + + L++D
Sbjct: 352 EELQMTRMLQRMDVLAKKATEMGVRLMVD 380
>AB166669-1|BAD12265.1| 66|Homo sapiens p53-inducible
ribonucleotide reductase small subunit 2 short form beta
protein.
Length = 66
Score = 30.3 bits (65), Expect = 6.3
Identities = 12/18 (66%), Positives = 14/18 (77%)
Frame = +3
Query: 600 YNTKNPFDFMNLISLEGK 653
+ +NPFDFM ISLEGK
Sbjct: 18 FQAENPFDFMENISLEGK 35
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 93,093,850
Number of Sequences: 237096
Number of extensions: 1909983
Number of successful extensions: 3734
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 3628
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3734
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7310122300
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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