Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= NRPG0631
(645 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein. 159 6e-39
M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein. 159 6e-39
M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein. 159 6e-39
CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein. 159 6e-39
BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal ... 159 6e-39
BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal ... 159 6e-39
BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein. 159 6e-39
BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic pepti... 143 4e-34
AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4 pro... 143 5e-34
AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor prot... 143 5e-34
AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein. 143 5e-34
BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein. 132 8e-31
AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3 pro... 132 8e-31
M26901-1|AAA60364.1| 403|Homo sapiens renin protein. 126 9e-29
M10152-1|AAD03461.1| 406|Homo sapiens renin protein. 126 9e-29
L00073-1|AAA60363.1| 406|Homo sapiens renin protein. 126 9e-29
CR536498-1|CAG38737.1| 406|Homo sapiens REN protein. 126 9e-29
BC047752-1|AAH47752.1| 406|Homo sapiens renin protein. 126 9e-29
BC033474-1|AAH33474.1| 406|Homo sapiens renin protein. 126 9e-29
AY436324-1|AAR03502.1| 403|Homo sapiens renin protein. 126 9e-29
AL592146-1|CAI16594.1| 406|Homo sapiens renin protein. 126 9e-29
AL592114-1|CAH71224.1| 406|Homo sapiens renin protein. 126 9e-29
J00287-1|AAA98529.1| 388|Homo sapiens PEP protein. 120 3e-27
BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I (... 120 3e-27
M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein. 119 8e-27
J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein. 119 8e-27
BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein. 119 8e-27
BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein. 119 8e-27
BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein. 119 8e-27
AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein. 119 8e-27
AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternativ... 119 8e-27
M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein. 119 1e-26
U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein. 117 3e-26
M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein. 117 3e-26
M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein. 117 3e-26
J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein. 117 3e-26
BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinog... 117 3e-26
AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinog... 117 3e-26
X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mR... 72 2e-12
BC042578-1|AAH42578.1| 104|Homo sapiens PGC protein protein. 60 7e-09
BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving ... 56 1e-07
AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein. 56 1e-07
AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein. 56 1e-07
AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic ... 56 1e-07
AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1 pro... 56 1e-07
AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein. 56 1e-07
AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein. 56 1e-07
AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein. 56 1e-07
AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein. 56 1e-07
AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease ... 56 1e-07
AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein. 56 1e-07
AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens ... 53 1e-06
DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving ... 44 6e-04
BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving ... 44 6e-04
AF338816-1|AAK38374.1| 476|Homo sapiens beta-site APP cleaving ... 44 6e-04
AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic ... 44 6e-04
AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase prot... 44 6e-04
AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2 pro... 44 6e-04
AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein. 44 6e-04
AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving ... 44 6e-04
AB050436-1|BAB40931.1| 476|Homo sapiens beta-site APP cleaving ... 44 6e-04
AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein. 44 6e-04
AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving ... 42 0.002
AB050438-1|BAB40933.1| 432|Homo sapiens beta-site APP cleaving ... 42 0.002
AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving ... 42 0.002
BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving ... 41 0.003
AL163285-1|CAB90554.1| 415|Homo sapiens beta-site APP-cleaving ... 39 0.013
AL365205-3|CAM16152.1| 86|Homo sapiens progastricsin (pepsinog... 39 0.017
AB089958-1|BAC81826.1| 127|Homo sapiens beta-site APP cleaving ... 37 0.071
AF141344-1|AAG49447.1| 119|Homo sapiens LYST-interacting protei... 32 1.5
AK055141-1|BAB70862.1| 260|Homo sapiens protein ( Homo sapiens ... 32 2.0
BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain cont... 31 4.6
BC035605-1|AAH35605.1| 578|Homo sapiens schlafen family member ... 25 5.9
AK001122-1|BAA91512.1| 578|Homo sapiens protein ( Homo sapiens ... 25 5.9
BC133035-1|AAI33036.1| 129|Homo sapiens keratin associated prot... 30 6.1
BC130399-1|AAI30400.1| 129|Homo sapiens keratin associated prot... 30 6.1
AB126075-1|BAD20202.1| 129|Homo sapiens keratin associated prot... 30 6.1
AK075015-1|BAC11354.1| 397|Homo sapiens protein ( Homo sapiens ... 24 8.0
AK096194-1|BAC04723.1| 138|Homo sapiens protein ( Homo sapiens ... 30 8.1
AB126079-1|BAD20206.1| 202|Homo sapiens keratin associated prot... 30 8.1
BC146666-1|AAI46667.1| 689|Homo sapiens SLC34A2 protein protein. 24 9.9
BC142704-1|AAI42705.1| 689|Homo sapiens SLC34A2 protein protein. 24 9.9
AF146796-1|AAF31328.1| 689|Homo sapiens sodium dependent phosph... 24 9.9
>X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 159 bits (387), Expect = 6e-39
Identities = 83/148 (56%), Positives = 97/148 (65%), Gaps = 11/148 (7%)
Frame = +1
Query: 226 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 372
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 373 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 552
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 553 YVANGTQFAIQYGSGSLSGFLSTDDVTV 636
YV NGT F I YGSGSLSG+LS D V+V
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSV 158
>M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 159 bits (387), Expect = 6e-39
Identities = 83/148 (56%), Positives = 97/148 (65%), Gaps = 11/148 (7%)
Frame = +1
Query: 226 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 372
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 373 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 552
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 553 YVANGTQFAIQYGSGSLSGFLSTDDVTV 636
YV NGT F I YGSGSLSG+LS D V+V
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSV 158
>M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 159 bits (387), Expect = 6e-39
Identities = 83/148 (56%), Positives = 97/148 (65%), Gaps = 11/148 (7%)
Frame = +1
Query: 226 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 372
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 373 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 552
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 553 YVANGTQFAIQYGSGSLSGFLSTDDVTV 636
YV NGT F I YGSGSLSG+LS D V+V
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSV 158
>CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 159 bits (387), Expect = 6e-39
Identities = 83/148 (56%), Positives = 97/148 (65%), Gaps = 11/148 (7%)
Frame = +1
Query: 226 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 372
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 373 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 552
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 553 YVANGTQFAIQYGSGSLSGFLSTDDVTV 636
YV NGT F I YGSGSLSG+LS D V+V
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSV 158
>BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 159 bits (387), Expect = 6e-39
Identities = 83/148 (56%), Positives = 97/148 (65%), Gaps = 11/148 (7%)
Frame = +1
Query: 226 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 372
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 373 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 552
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 553 YVANGTQFAIQYGSGSLSGFLSTDDVTV 636
YV NGT F I YGSGSLSG+LS D V+V
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSV 158
>BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 159 bits (387), Expect = 6e-39
Identities = 83/148 (56%), Positives = 97/148 (65%), Gaps = 11/148 (7%)
Frame = +1
Query: 226 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 372
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 373 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 552
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 553 YVANGTQFAIQYGSGSLSGFLSTDDVTV 636
YV NGT F I YGSGSLSG+LS D V+V
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSV 158
>BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 159 bits (387), Expect = 6e-39
Identities = 83/148 (56%), Positives = 97/148 (65%), Gaps = 11/148 (7%)
Frame = +1
Query: 226 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 372
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 373 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 552
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 553 YVANGTQFAIQYGSGSLSGFLSTDDVTV 636
YV NGT F I YGSGSLSG+LS D V+V
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSV 158
>BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic
peptidase protein.
Length = 420
Score = 143 bits (347), Expect = 4e-34
Identities = 67/142 (47%), Positives = 94/142 (66%), Gaps = 5/142 (3%)
Frame = +1
Query: 235 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 399
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRTLNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 400 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFA 579
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S ++ ANGT+FA
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFA 138
Query: 580 IQYGSGSLSGFLSTDDVTVGGL 645
IQYG+G + G LS D +T+GG+
Sbjct: 139 IQYGTGRVDGILSEDKLTIGGI 160
>AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4
protein.
Length = 420
Score = 143 bits (346), Expect = 5e-34
Identities = 67/142 (47%), Positives = 94/142 (66%), Gaps = 5/142 (3%)
Frame = +1
Query: 235 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 399
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 400 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFA 579
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S ++ ANGT+FA
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFA 138
Query: 580 IQYGSGSLSGFLSTDDVTVGGL 645
IQYG+G + G LS D +T+GG+
Sbjct: 139 IQYGTGRVDGILSEDKLTIGGI 160
>AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor
protein.
Length = 420
Score = 143 bits (346), Expect = 5e-34
Identities = 67/142 (47%), Positives = 94/142 (66%), Gaps = 5/142 (3%)
Frame = +1
Query: 235 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 399
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 400 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFA 579
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S ++ ANGT+FA
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFA 138
Query: 580 IQYGSGSLSGFLSTDDVTVGGL 645
IQYG+G + G LS D +T+GG+
Sbjct: 139 IQYGTGRVDGILSEDKLTIGGI 160
>AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein.
Length = 420
Score = 143 bits (346), Expect = 5e-34
Identities = 67/142 (47%), Positives = 94/142 (66%), Gaps = 5/142 (3%)
Frame = +1
Query: 235 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 399
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 400 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFA 579
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S ++ ANGT+FA
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFA 138
Query: 580 IQYGSGSLSGFLSTDDVTVGGL 645
IQYG+G + G LS D +T+GG+
Sbjct: 139 IQYGTGRVDGILSEDKLTIGGI 160
>BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein.
Length = 464
Score = 132 bits (320), Expect = 8e-31
Identities = 61/135 (45%), Positives = 89/135 (65%), Gaps = 5/135 (3%)
Frame = +1
Query: 256 LYRVPLHRMKTARTHFHEV---GTELELLRLKYDVTGPSPE--PLSNYLDAQYYGVISIG 420
L R+PL ++ R + + G EL +L G P PLS +LDAQY+G I +G
Sbjct: 22 LIRIPLRQVHPGRRTLNLLRGWGKPAELPKLGAPSPGDKPASVPLSKFLDAQYFGEIGLG 81
Query: 421 TPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGS 600
TPPQ+F V FDTGSSNLWVPS++CH+ ++ C H++++ S ++ +GT+FAIQYG+G
Sbjct: 82 TPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWFHHRFNPNASSSFKPSGTKFAIQYGTGR 141
Query: 601 LSGFLSTDDVTVGGL 645
+ G LS D +T+GG+
Sbjct: 142 VDGILSEDKLTIGGI 156
>AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3
protein.
Length = 450
Score = 132 bits (320), Expect = 8e-31
Identities = 61/135 (45%), Positives = 89/135 (65%), Gaps = 5/135 (3%)
Frame = +1
Query: 256 LYRVPLHRMKTARTHFHEV---GTELELLRLKYDVTGPSPE--PLSNYLDAQYYGVISIG 420
L R+PL ++ R + + G EL +L G P PLS +LDAQY+G I +G
Sbjct: 26 LIRIPLRQVHPGRRTLNLLRGWGKPAELPKLGAPSPGDKPASVPLSKFLDAQYFGEIGLG 85
Query: 421 TPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGS 600
TPPQ+F V FDTGSSNLWVPS++CH+ ++ C H++++ S ++ +GT+FAIQYG+G
Sbjct: 86 TPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWFHHRFNPNASSSFKPSGTKFAIQYGTGR 145
Query: 601 LSGFLSTDDVTVGGL 645
+ G LS D +T+GG+
Sbjct: 146 VDGILSEDKLTIGGI 160
>M26901-1|AAA60364.1| 403|Homo sapiens renin protein.
Length = 403
Score = 126 bits (303), Expect = 9e-29
Identities = 53/91 (58%), Positives = 69/91 (75%)
Frame = +1
Query: 373 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 552
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 553 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 645
Y NGT+ ++Y +G++SGFLS D +TVGG+
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGI 168
>M10152-1|AAD03461.1| 406|Homo sapiens renin protein.
Length = 406
Score = 126 bits (303), Expect = 9e-29
Identities = 53/91 (58%), Positives = 69/91 (75%)
Frame = +1
Query: 373 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 552
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 553 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 645
Y NGT+ ++Y +G++SGFLS D +TVGG+
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGI 168
>L00073-1|AAA60363.1| 406|Homo sapiens renin protein.
Length = 406
Score = 126 bits (303), Expect = 9e-29
Identities = 53/91 (58%), Positives = 69/91 (75%)
Frame = +1
Query: 373 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 552
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 553 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 645
Y NGT+ ++Y +G++SGFLS D +TVGG+
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGI 168
>CR536498-1|CAG38737.1| 406|Homo sapiens REN protein.
Length = 406
Score = 126 bits (303), Expect = 9e-29
Identities = 53/91 (58%), Positives = 69/91 (75%)
Frame = +1
Query: 373 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 552
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 553 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 645
Y NGT+ ++Y +G++SGFLS D +TVGG+
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGI 168
>BC047752-1|AAH47752.1| 406|Homo sapiens renin protein.
Length = 406
Score = 126 bits (303), Expect = 9e-29
Identities = 53/91 (58%), Positives = 69/91 (75%)
Frame = +1
Query: 373 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 552
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 553 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 645
Y NGT+ ++Y +G++SGFLS D +TVGG+
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGI 168
>BC033474-1|AAH33474.1| 406|Homo sapiens renin protein.
Length = 406
Score = 126 bits (303), Expect = 9e-29
Identities = 53/91 (58%), Positives = 69/91 (75%)
Frame = +1
Query: 373 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 552
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 553 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 645
Y NGT+ ++Y +G++SGFLS D +TVGG+
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGI 168
>AY436324-1|AAR03502.1| 403|Homo sapiens renin protein.
Length = 403
Score = 126 bits (303), Expect = 9e-29
Identities = 53/91 (58%), Positives = 69/91 (75%)
Frame = +1
Query: 373 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 552
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 553 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 645
Y NGT+ ++Y +G++SGFLS D +TVGG+
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGI 168
>AL592146-1|CAI16594.1| 406|Homo sapiens renin protein.
Length = 406
Score = 126 bits (303), Expect = 9e-29
Identities = 53/91 (58%), Positives = 69/91 (75%)
Frame = +1
Query: 373 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 552
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 553 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 645
Y NGT+ ++Y +G++SGFLS D +TVGG+
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGI 168
>AL592114-1|CAH71224.1| 406|Homo sapiens renin protein.
Length = 406
Score = 126 bits (303), Expect = 9e-29
Identities = 53/91 (58%), Positives = 69/91 (75%)
Frame = +1
Query: 373 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 552
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 553 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 645
Y NGT+ ++Y +G++SGFLS D +TVGG+
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGI 168
>J00287-1|AAA98529.1| 388|Homo sapiens PEP protein.
Length = 388
Score = 120 bits (290), Expect = 3e-27
Identities = 67/155 (43%), Positives = 89/155 (57%), Gaps = 12/155 (7%)
Frame = +1
Query: 217 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 366
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLV 63
Query: 367 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSR 540
+PL NYLD +Y+G I IGTP Q F VVFDTGSSNLWVPS C +++AC HN+++
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYC--SSLACTNHNRFNPE 121
Query: 541 KSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 645
S TY + +I YG+GS++G L D V VGG+
Sbjct: 122 DSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGI 156
>BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I
(pepsinogen A) protein.
Length = 388
Score = 120 bits (290), Expect = 3e-27
Identities = 67/155 (43%), Positives = 89/155 (57%), Gaps = 12/155 (7%)
Frame = +1
Query: 217 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 366
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLV 63
Query: 367 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSR 540
+PL NYLD +Y+G I IGTP Q F VVFDTGSSNLWVPS C +++AC HN+++
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYC--SSLACTNHNRFNPE 121
Query: 541 KSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 645
S TY + +I YG+GS++G L D V VGG+
Sbjct: 122 DSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGI 156
>M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 119 bits (287), Expect = 8e-27
Identities = 66/153 (43%), Positives = 91/153 (59%), Gaps = 10/153 (6%)
Frame = +1
Query: 217 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 366
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 367 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 546
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 547 KTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 645
TY G F+IQYG+GSLSG + D V+V GL
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGL 158
>J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein.
Length = 396
Score = 119 bits (287), Expect = 8e-27
Identities = 66/153 (43%), Positives = 91/153 (59%), Gaps = 10/153 (6%)
Frame = +1
Query: 217 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 366
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 367 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 546
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 547 KTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 645
TY G F+IQYG+GSLSG + D V+V GL
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGL 158
>BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein.
Length = 363
Score = 119 bits (287), Expect = 8e-27
Identities = 66/153 (43%), Positives = 91/153 (59%), Gaps = 10/153 (6%)
Frame = +1
Query: 217 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 366
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 367 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 546
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 547 KTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 645
TY G F+IQYG+GSLSG + D V+V GL
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGL 158
>BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 119 bits (287), Expect = 8e-27
Identities = 66/153 (43%), Positives = 91/153 (59%), Gaps = 10/153 (6%)
Frame = +1
Query: 217 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 366
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 367 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 546
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 547 KTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 645
TY G F+IQYG+GSLSG + D V+V GL
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGL 158
>BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 119 bits (287), Expect = 8e-27
Identities = 66/153 (43%), Positives = 91/153 (59%), Gaps = 10/153 (6%)
Frame = +1
Query: 217 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 366
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 367 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 546
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 547 KTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 645
TY G F+IQYG+GSLSG + D V+V GL
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGL 158
>AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein.
Length = 396
Score = 119 bits (287), Expect = 8e-27
Identities = 66/153 (43%), Positives = 91/153 (59%), Gaps = 10/153 (6%)
Frame = +1
Query: 217 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 366
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 367 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 546
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 547 KTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 645
TY G F+IQYG+GSLSG + D V+V GL
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGL 158
>AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternative
protein.
Length = 363
Score = 119 bits (287), Expect = 8e-27
Identities = 66/153 (43%), Positives = 91/153 (59%), Gaps = 10/153 (6%)
Frame = +1
Query: 217 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 366
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 367 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 546
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 547 KTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 645
TY G F+IQYG+GSLSG + D V+V GL
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGL 158
>M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein.
Length = 388
Score = 119 bits (286), Expect = 1e-26
Identities = 66/155 (42%), Positives = 89/155 (57%), Gaps = 12/155 (7%)
Frame = +1
Query: 217 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 366
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSFRRTLSERGLLKDFLKKHNLNPARKYFPQWKAPTLV 63
Query: 367 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSR 540
+PL NYLD +Y+G I IGTP Q F V+FDTGSSNLWVPS C +++AC HN+++
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVLFDTGSSNLWVPSVYC--SSLACTNHNRFNPE 121
Query: 541 KSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGL 645
S TY + +I YG+GS++G L D V VGG+
Sbjct: 122 DSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGI 156
>U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein.
Length = 388
Score = 117 bits (282), Expect = 3e-26
Identities = 65/137 (47%), Positives = 86/137 (62%), Gaps = 9/137 (6%)
Frame = +1
Query: 253 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 405
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 406 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQ 585
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 586 YGSGSLSGFLSTDDVTV 636
YGSGSL+GF D +TV
Sbjct: 134 YGSGSLTGFFGYDTLTV 150
>M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein.
Length = 388
Score = 117 bits (282), Expect = 3e-26
Identities = 65/137 (47%), Positives = 86/137 (62%), Gaps = 9/137 (6%)
Frame = +1
Query: 253 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 405
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 406 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQ 585
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 586 YGSGSLSGFLSTDDVTV 636
YGSGSL+GF D +TV
Sbjct: 134 YGSGSLTGFFGYDTLTV 150
>M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein.
Length = 385
Score = 117 bits (282), Expect = 3e-26
Identities = 65/137 (47%), Positives = 86/137 (62%), Gaps = 9/137 (6%)
Frame = +1
Query: 253 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 405
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 14 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 72
Query: 406 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQ 585
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 73 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 130
Query: 586 YGSGSLSGFLSTDDVTV 636
YGSGSL+GF D +TV
Sbjct: 131 YGSGSLTGFFGYDTLTV 147
>J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein.
Length = 388
Score = 117 bits (282), Expect = 3e-26
Identities = 65/137 (47%), Positives = 86/137 (62%), Gaps = 9/137 (6%)
Frame = +1
Query: 253 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 405
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 406 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQ 585
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 586 YGSGSLSGFLSTDDVTV 636
YGSGSL+GF D +TV
Sbjct: 134 YGSGSLTGFFGYDTLTV 150
>BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 117 bits (282), Expect = 3e-26
Identities = 65/137 (47%), Positives = 86/137 (62%), Gaps = 9/137 (6%)
Frame = +1
Query: 253 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 405
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 406 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQ 585
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 586 YGSGSLSGFLSTDDVTV 636
YGSGSL+GF D +TV
Sbjct: 134 YGSGSLTGFFGYDTLTV 150
>AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 117 bits (282), Expect = 3e-26
Identities = 65/137 (47%), Positives = 86/137 (62%), Gaps = 9/137 (6%)
Frame = +1
Query: 253 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 405
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 406 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQ 585
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 586 YGSGSLSGFLSTDDVTV 636
YGSGSL+GF D +TV
Sbjct: 134 YGSGSLTGFFGYDTLTV 150
>X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mRNA
fragment for renin (aa 105-401). ).
Length = 300
Score = 72.1 bits (169), Expect = 2e-12
Identities = 29/61 (47%), Positives = 42/61 (68%)
Frame = +1
Query: 463 SNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGG 642
SN+WVPS KC AC+ H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG
Sbjct: 1 SNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGG 60
Query: 643 L 645
+
Sbjct: 61 I 61
>BC042578-1|AAH42578.1| 104|Homo sapiens PGC protein protein.
Length = 104
Score = 60.1 bits (139), Expect = 7e-09
Identities = 38/82 (46%), Positives = 49/82 (59%), Gaps = 9/82 (10%)
Frame = +1
Query: 253 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 405
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 406 VISIGTPPQSFKVVFDTGSSNL 471
ISIGTPPQ+F V+FDTGSS L
Sbjct: 76 EISIGTPPQNFLVLFDTGSSPL 97
>BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving
enzyme 2 protein.
Length = 518
Score = 55.6 bits (128), Expect = 1e-07
Identities = 29/80 (36%), Positives = 43/80 (53%)
Frame = +1
Query: 397 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 576
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 577 AIQYGSGSLSGFLSTDDVTV 636
++Y GS +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein.
Length = 518
Score = 55.6 bits (128), Expect = 1e-07
Identities = 29/80 (36%), Positives = 43/80 (53%)
Frame = +1
Query: 397 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 576
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 577 AIQYGSGSLSGFLSTDDVTV 636
++Y GS +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein.
Length = 439
Score = 55.6 bits (128), Expect = 1e-07
Identities = 29/80 (36%), Positives = 43/80 (53%)
Frame = +1
Query: 397 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 576
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 13 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 66
Query: 577 AIQYGSGSLSGFLSTDDVTV 636
++Y GS +GF+ D VT+
Sbjct: 67 TVKYTQGSWTGFVGEDLVTI 86
>AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic
proteinase Asp 1 protein.
Length = 518
Score = 55.6 bits (128), Expect = 1e-07
Identities = 29/80 (36%), Positives = 43/80 (53%)
Frame = +1
Query: 397 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 576
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 577 AIQYGSGSLSGFLSTDDVTV 636
++Y GS +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1
protein.
Length = 518
Score = 55.6 bits (128), Expect = 1e-07
Identities = 29/80 (36%), Positives = 43/80 (53%)
Frame = +1
Query: 397 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 576
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 577 AIQYGSGSLSGFLSTDDVTV 636
++Y GS +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein.
Length = 518
Score = 55.6 bits (128), Expect = 1e-07
Identities = 29/80 (36%), Positives = 43/80 (53%)
Frame = +1
Query: 397 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 576
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 577 AIQYGSGSLSGFLSTDDVTV 636
++Y GS +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein.
Length = 396
Score = 55.6 bits (128), Expect = 1e-07
Identities = 29/80 (36%), Positives = 43/80 (53%)
Frame = +1
Query: 397 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 576
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 577 AIQYGSGSLSGFLSTDDVTV 636
++Y GS +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein.
Length = 468
Score = 55.6 bits (128), Expect = 1e-07
Identities = 29/80 (36%), Positives = 43/80 (53%)
Frame = +1
Query: 397 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 576
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 577 AIQYGSGSLSGFLSTDDVTV 636
++Y GS +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 55.6 bits (128), Expect = 1e-07
Identities = 29/80 (36%), Positives = 43/80 (53%)
Frame = +1
Query: 397 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 576
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 577 AIQYGSGSLSGFLSTDDVTV 636
++Y GS +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease
protein.
Length = 518
Score = 55.6 bits (128), Expect = 1e-07
Identities = 29/80 (36%), Positives = 43/80 (53%)
Frame = +1
Query: 397 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 576
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 577 AIQYGSGSLSGFLSTDDVTV 636
++Y GS +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 55.6 bits (128), Expect = 1e-07
Identities = 29/80 (36%), Positives = 43/80 (53%)
Frame = +1
Query: 397 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 576
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 577 AIQYGSGSLSGFLSTDDVTV 636
++Y GS +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens
cDNA PSEC0239 fis, clone OVARC1000363, highly similar to
Homo sapiens aspartyl protease mRNA. ).
Length = 423
Score = 52.8 bits (121), Expect = 1e-06
Identities = 27/74 (36%), Positives = 40/74 (54%)
Frame = +1
Query: 415 IGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGS 594
IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G ++Y
Sbjct: 3 IGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDVTVKYTQ 56
Query: 595 GSLSGFLSTDDVTV 636
GS +GF+ D VT+
Sbjct: 57 GSWTGFVGEDLVTI 70
>DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 43.6 bits (98), Expect = 6e-04
Identities = 26/80 (32%), Positives = 39/80 (48%)
Frame = +1
Query: 397 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 576
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 577 AIQYGSGSLSGFLSTDDVTV 636
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 43.6 bits (98), Expect = 6e-04
Identities = 26/80 (32%), Positives = 39/80 (48%)
Frame = +1
Query: 397 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 576
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 577 AIQYGSGSLSGFLSTDDVTV 636
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>AF338816-1|AAK38374.1| 476|Homo sapiens beta-site APP cleaving
enzyme type B protein.
Length = 476
Score = 43.6 bits (98), Expect = 6e-04
Identities = 26/80 (32%), Positives = 39/80 (48%)
Frame = +1
Query: 397 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 576
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 577 AIQYGSGSLSGFLSTDDVTV 636
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic
proteinase Asp 2 protein.
Length = 501
Score = 43.6 bits (98), Expect = 6e-04
Identities = 26/80 (32%), Positives = 39/80 (48%)
Frame = +1
Query: 397 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 576
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 577 AIQYGSGSLSGFLSTDDVTV 636
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase
protein.
Length = 501
Score = 43.6 bits (98), Expect = 6e-04
Identities = 26/80 (32%), Positives = 39/80 (48%)
Frame = +1
Query: 397 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 576
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 577 AIQYGSGSLSGFLSTDDVTV 636
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2
protein.
Length = 501
Score = 43.6 bits (98), Expect = 6e-04
Identities = 26/80 (32%), Positives = 39/80 (48%)
Frame = +1
Query: 397 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 576
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 577 AIQYGSGSLSGFLSTDDVTV 636
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein.
Length = 488
Score = 43.6 bits (98), Expect = 6e-04
Identities = 26/80 (32%), Positives = 39/80 (48%)
Frame = +1
Query: 397 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 576
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 62 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 115
Query: 577 AIQYGSGSLSGFLSTDDVTV 636
+ Y G G L TD V++
Sbjct: 116 YVPYTQGKWEGELGTDLVSI 135
>AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving
enzyme protein.
Length = 501
Score = 43.6 bits (98), Expect = 6e-04
Identities = 26/80 (32%), Positives = 39/80 (48%)
Frame = +1
Query: 397 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 576
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 577 AIQYGSGSLSGFLSTDDVTV 636
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>AB050436-1|BAB40931.1| 476|Homo sapiens beta-site APP cleaving
enzyme I-476 protein.
Length = 476
Score = 43.6 bits (98), Expect = 6e-04
Identities = 26/80 (32%), Positives = 39/80 (48%)
Frame = +1
Query: 397 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 576
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 577 AIQYGSGSLSGFLSTDDVTV 636
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein.
Length = 532
Score = 43.6 bits (98), Expect = 6e-04
Identities = 26/80 (32%), Positives = 39/80 (48%)
Frame = +1
Query: 397 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 576
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 106 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 159
Query: 577 AIQYGSGSLSGFLSTDDVTV 636
+ Y G G L TD V++
Sbjct: 160 YVPYTQGKWEGELGTDLVSI 179
>AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving
enzyme type C protein.
Length = 457
Score = 41.9 bits (94), Expect = 0.002
Identities = 25/76 (32%), Positives = 36/76 (47%)
Frame = +1
Query: 397 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 576
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 577 AIQYGSGSLSGFLSTD 624
+ Y G G L TD
Sbjct: 129 YVPYTQGKWEGELGTD 144
>AB050438-1|BAB40933.1| 432|Homo sapiens beta-site APP cleaving
enzyme I-432 protein.
Length = 432
Score = 41.9 bits (94), Expect = 0.002
Identities = 25/76 (32%), Positives = 36/76 (47%)
Frame = +1
Query: 397 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 576
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 577 AIQYGSGSLSGFLSTD 624
+ Y G G L TD
Sbjct: 129 YVPYTQGKWEGELGTD 144
>AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving
enzyme I-457 protein.
Length = 457
Score = 41.9 bits (94), Expect = 0.002
Identities = 25/76 (32%), Positives = 36/76 (47%)
Frame = +1
Query: 397 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 576
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 577 AIQYGSGSLSGFLSTD 624
+ Y G G L TD
Sbjct: 129 YVPYTQGKWEGELGTD 144
>BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 41.1 bits (92), Expect = 0.003
Identities = 25/80 (31%), Positives = 38/80 (47%)
Frame = +1
Query: 397 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 576
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLFSTYRDLRKGV 128
Query: 577 AIQYGSGSLSGFLSTDDVTV 636
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>AL163285-1|CAB90554.1| 415|Homo sapiens beta-site APP-cleaving
enzyme 2, EC 3.4.23. protein.
Length = 415
Score = 39.1 bits (87), Expect = 0.013
Identities = 21/66 (31%), Positives = 34/66 (51%)
Frame = +1
Query: 439 KVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLS 618
+++ DTGSSN V Y + +D+ +S TY + G ++Y GS +GF+
Sbjct: 3 QILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVG 56
Query: 619 TDDVTV 636
D VT+
Sbjct: 57 EDLVTI 62
>AL365205-3|CAM16152.1| 86|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 86
Score = 38.7 bits (86), Expect = 0.017
Identities = 28/70 (40%), Positives = 37/70 (52%), Gaps = 9/70 (12%)
Frame = +1
Query: 244 SVMALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQ 396
+V+ RVPL + K+ R E G E LR KYD + EP++ Y+DA
Sbjct: 18 AVICKQRVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAA 76
Query: 397 YYGVISIGTP 426
Y+G ISIGTP
Sbjct: 77 YFGEISIGTP 86
>AB089958-1|BAC81826.1| 127|Homo sapiens beta-site APP cleaving
enzyme isoform I-127 protein.
Length = 127
Score = 36.7 bits (81), Expect = 0.071
Identities = 19/53 (35%), Positives = 29/53 (54%)
Frame = +1
Query: 397 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTY 555
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 121
>AF141344-1|AAG49447.1| 119|Homo sapiens LYST-interacting protein
LIP8 protein.
Length = 119
Score = 32.3 bits (70), Expect = 1.5
Identities = 13/33 (39%), Positives = 16/33 (48%)
Frame = -3
Query: 619 WRGSRRGCRSRTVSRTGCHSRRTSWTCGCRTCC 521
W GS+R C + V + S SW CR CC
Sbjct: 8 WPGSKRECANCRVGTSSWRSSGWSWWKDCRPCC 40
>AK055141-1|BAB70862.1| 260|Homo sapiens protein ( Homo sapiens
cDNA FLJ30579 fis, clone BRAWH2006989, weakly similar to
DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT (EC
2.7.7.6). ).
Length = 260
Score = 31.9 bits (69), Expect = 2.0
Identities = 17/35 (48%), Positives = 18/35 (51%)
Frame = -3
Query: 628 HHQWRGSRRGCRSRTVSRTGCHSRRTSWTCGCRTC 524
H+ W GS R C S T S G HS SWT R C
Sbjct: 26 HNSWTGSNRACSSWTGSTRG-HS---SWTGSSRAC 56
>BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain
containing 11 protein.
Length = 514
Score = 30.7 bits (66), Expect = 4.6
Identities = 12/26 (46%), Positives = 18/26 (69%)
Frame = -1
Query: 462 GSGVEYHLERLRRRADTDHSVVLSIK 385
G G E+HLER+RR ++++ SIK
Sbjct: 30 GQGAEHHLERIRRSHQKHNAILASIK 55
>BC035605-1|AAH35605.1| 578|Homo sapiens schlafen family member 12
protein.
Length = 578
Score = 25.4 bits (53), Expect(2) = 5.9
Identities = 12/51 (23%), Positives = 23/51 (45%)
Frame = -3
Query: 388 QDNLTMVRVKGQSHRILISTAPVQCQPHESGFSQFSYDVMAPYIVPLRSWR 236
+DN M + + + ++ P +E SQ + + AP+ PL W+
Sbjct: 325 KDNRVMQLTRKEWIQFMVEAEPKFSSSYEEVISQINTSLPAPHSWPLLEWQ 375
Score = 23.4 bits (48), Expect(2) = 5.9
Identities = 8/27 (29%), Positives = 11/27 (40%)
Frame = -3
Query: 535 CRTCCAANKRCWCSGTFWKAPRGWRIR 455
C CA +C F K P W ++
Sbjct: 299 CGYVCALRVERFCCAVFAKEPDSWHVK 325
>AK001122-1|BAA91512.1| 578|Homo sapiens protein ( Homo sapiens
cDNA FLJ10260 fis, clone HEMBB1000973, moderately
similar to Mus musculus schlafen3 mRNA. ).
Length = 578
Score = 25.4 bits (53), Expect(2) = 5.9
Identities = 12/51 (23%), Positives = 23/51 (45%)
Frame = -3
Query: 388 QDNLTMVRVKGQSHRILISTAPVQCQPHESGFSQFSYDVMAPYIVPLRSWR 236
+DN M + + + ++ P +E SQ + + AP+ PL W+
Sbjct: 325 KDNRVMQLTRKEWIQFMVEAEPKFSSSYEEVISQINASLPAPHSWPLLEWQ 375
Score = 23.4 bits (48), Expect(2) = 5.9
Identities = 8/27 (29%), Positives = 11/27 (40%)
Frame = -3
Query: 535 CRTCCAANKRCWCSGTFWKAPRGWRIR 455
C CA +C F K P W ++
Sbjct: 299 CGYVCALRVERFCCAVFAKEPDSWHVK 325
>BC133035-1|AAI33036.1| 129|Homo sapiens keratin associated protein
5-6 protein.
Length = 129
Score = 30.3 bits (65), Expect = 6.1
Identities = 17/40 (42%), Positives = 20/40 (50%)
Frame = -3
Query: 613 GSRRGCRSRTVSRTGCHSRRTSWTCGCRTCCAANKRCWCS 494
GS+ GC S S+ GC S CGC C K C+CS
Sbjct: 65 GSKGGCGSCGGSKGGCGS------CGCSQCSCC-KPCYCS 97
>BC130399-1|AAI30400.1| 129|Homo sapiens keratin associated protein
5-6 protein.
Length = 129
Score = 30.3 bits (65), Expect = 6.1
Identities = 17/40 (42%), Positives = 20/40 (50%)
Frame = -3
Query: 613 GSRRGCRSRTVSRTGCHSRRTSWTCGCRTCCAANKRCWCS 494
GS+ GC S S+ GC S CGC C K C+CS
Sbjct: 65 GSKGGCGSCGGSKGGCGS------CGCSQCSCC-KPCYCS 97
>AB126075-1|BAD20202.1| 129|Homo sapiens keratin associated protein
protein.
Length = 129
Score = 30.3 bits (65), Expect = 6.1
Identities = 17/40 (42%), Positives = 20/40 (50%)
Frame = -3
Query: 613 GSRRGCRSRTVSRTGCHSRRTSWTCGCRTCCAANKRCWCS 494
GS+ GC S S+ GC S CGC C K C+CS
Sbjct: 65 GSKGGCGSCGGSKGGCGS------CGCSQCSCC-KPCYCS 97
>AK075015-1|BAC11354.1| 397|Homo sapiens protein ( Homo sapiens
cDNA FLJ90534 fis, clone OVARC1000003, highly similar to
Homo sapiens sodium dependent phosphate transporter
isoform ).
Length = 397
Score = 24.2 bits (50), Expect(2) = 8.0
Identities = 13/41 (31%), Positives = 16/41 (39%)
Frame = -3
Query: 637 PR*HHQWRGSRRGCRSRTVSRTGCHSRRTSWTCGCRTCCAA 515
P+ W S + + TGC R C CR CC A
Sbjct: 297 PKKLQNWMRSLKPWDAVVSKFTGCFQMRCC--CCCRVCCRA 335
Score = 24.2 bits (50), Expect(2) = 8.0
Identities = 7/13 (53%), Positives = 8/13 (61%)
Frame = -3
Query: 541 CGCRTCCAANKRC 503
CGC CC +K C
Sbjct: 340 CGCPKCCRCSKCC 352
>AK096194-1|BAC04723.1| 138|Homo sapiens protein ( Homo sapiens
cDNA FLJ38875 fis, clone MESAN2013936. ).
Length = 138
Score = 29.9 bits (64), Expect = 8.1
Identities = 14/45 (31%), Positives = 19/45 (42%)
Frame = -3
Query: 598 CRSRTVSRTGCHSRRTSWTCGCRTCCAANKRCWCSGTFWKAPRGW 464
C S T C R + C +CC + + C CS T+W W
Sbjct: 75 CLSEEAGETAC--RASPGQCYVTSCCLS-RHCTCSLTWWDVLLNW 116
>AB126079-1|BAD20206.1| 202|Homo sapiens keratin associated protein
protein.
Length = 202
Score = 29.9 bits (64), Expect = 8.1
Identities = 18/66 (27%), Positives = 29/66 (43%)
Frame = -3
Query: 613 GSRRGCRSRTVSRTGCHSRRTSWTCGCRTCCAANKRCWCSGTFWKAPRGWRIRCRIPP*T 434
GS+ GC S S+ GC S S C+ CC ++ C + P + C +P
Sbjct: 119 GSKGGCGSCGGSKGGCGSCGCSQCNCCKPCCCSSGCGSCCQSSCCNPCCCQSSCCVPVCC 178
Query: 433 TAAACR 416
++ C+
Sbjct: 179 QSSCCK 184
>BC146666-1|AAI46667.1| 689|Homo sapiens SLC34A2 protein protein.
Length = 689
Score = 24.2 bits (50), Expect(2) = 9.9
Identities = 7/13 (53%), Positives = 8/13 (61%)
Frame = -3
Query: 541 CGCRTCCAANKRC 503
CGC CC +K C
Sbjct: 632 CGCPKCCRCSKCC 644
Score = 23.8 bits (49), Expect(2) = 9.9
Identities = 10/20 (50%), Positives = 10/20 (50%)
Frame = -3
Query: 574 TGCHSRRTSWTCGCRTCCAA 515
TGC R C CR CC A
Sbjct: 610 TGCFQMRCC--CCCRVCCRA 627
>BC142704-1|AAI42705.1| 689|Homo sapiens SLC34A2 protein protein.
Length = 689
Score = 24.2 bits (50), Expect(2) = 9.9
Identities = 7/13 (53%), Positives = 8/13 (61%)
Frame = -3
Query: 541 CGCRTCCAANKRC 503
CGC CC +K C
Sbjct: 632 CGCPKCCRCSKCC 644
Score = 23.8 bits (49), Expect(2) = 9.9
Identities = 10/20 (50%), Positives = 10/20 (50%)
Frame = -3
Query: 574 TGCHSRRTSWTCGCRTCCAA 515
TGC R C CR CC A
Sbjct: 610 TGCFQMRCC--CCCRVCCRA 627
>AF146796-1|AAF31328.1| 689|Homo sapiens sodium dependent phosphate
transporter isoform NaPi-IIb protein.
Length = 689
Score = 24.2 bits (50), Expect(2) = 9.9
Identities = 7/13 (53%), Positives = 8/13 (61%)
Frame = -3
Query: 541 CGCRTCCAANKRC 503
CGC CC +K C
Sbjct: 632 CGCPKCCRCSKCC 644
Score = 23.8 bits (49), Expect(2) = 9.9
Identities = 10/20 (50%), Positives = 10/20 (50%)
Frame = -3
Query: 574 TGCHSRRTSWTCGCRTCCAA 515
TGC R C CR CC A
Sbjct: 610 TGCFQMRCC--CCCRVCCRA 627
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 92,894,330
Number of Sequences: 237096
Number of extensions: 2069803
Number of successful extensions: 4514
Number of sequences better than 10.0: 83
Number of HSP's better than 10.0 without gapping: 4263
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4475
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7141427170
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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