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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= NRPG0525
         (624 letters)

Database: nematostella 
           59,808 sequences; 16,821,457 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

SB_37033| Best HMM Match : Annexin (HMM E-Value=0)                    137   6e-33
SB_47771| Best HMM Match : Annexin (HMM E-Value=0)                     93   6e-22
SB_26806| Best HMM Match : Annexin (HMM E-Value=0)                     94   1e-19
SB_35578| Best HMM Match : Annexin (HMM E-Value=1e-19)                 91   5e-19
SB_7681| Best HMM Match : Annexin (HMM E-Value=0)                      66   2e-11
SB_6006| Best HMM Match : Annexin (HMM E-Value=2.4e-25)                57   1e-08
SB_32965| Best HMM Match : Kazal_1 (HMM E-Value=3.4e-19)               30   1.8  
SB_56182| Best HMM Match : No HMM Matches (HMM E-Value=.)              28   5.4  
SB_34906| Best HMM Match : Cadherin (HMM E-Value=0)                    28   7.1  

>SB_37033| Best HMM Match : Annexin (HMM E-Value=0)
          Length = 287

 Score =  137 bits (332), Expect = 6e-33
 Identities = 64/126 (50%), Positives = 90/126 (71%)
 Frame = +3

Query: 195 GTDEKSIIQVLTKRSNEQRLRIALEFKTLYGKDLISDIKSETSGKFEDLLIALLTPLPKF 374
           G D K+++ +L  R+N QR RI+LE+KT++G+DLI D+KSE  G FED +IAL+TP  ++
Sbjct: 101 GCDNKALMYLLCSRTNSQRQRISLEYKTMFGRDLIKDLKSEVGGYFEDTVIALMTPPAEY 160

Query: 375 YAKELHEAMVGIGTDEGVLIEVMCTMSNYEIHSIEQAYTAIYGKILEDDIRGDTSGNFNR 554
            A  L +A+ G+GTDE VLIEV+ T +N EI +I  AY  ++ + LE DI GDTSG F +
Sbjct: 161 DATLLRKAIKGLGTDEAVLIEVLTTRTNDEIIAIRNAYNTLFSRDLEKDIAGDTSGKFKK 220

Query: 555 LMTSLC 572
            + SLC
Sbjct: 221 FLISLC 226



 Score = 72.1 bits (169), Expect = 3e-13
 Identities = 35/71 (49%), Positives = 49/71 (69%)
 Frame = +3

Query: 159 DAGVLRKAMKGFGTDEKSIIQVLTKRSNEQRLRIALEFKTLYGKDLISDIKSETSGKFED 338
           DA +LRKA+KG GTDE  +I+VLT R+N++ + I   + TL+ +DL  DI  +TSGKF+ 
Sbjct: 161 DATLLRKAIKGLGTDEAVLIEVLTTRTNDEIIAIRNAYNTLFSRDLEKDIAGDTSGKFKK 220

Query: 339 LLIALLTPLPK 371
            LI+L   L K
Sbjct: 221 FLISLCNALYK 231


>SB_47771| Best HMM Match : Annexin (HMM E-Value=0)
          Length = 529

 Score = 93.1 bits (221), Expect(2) = 6e-22
 Identities = 48/93 (51%), Positives = 63/93 (67%)
 Frame = +3

Query: 123 TVFPVNPFNPREDAGVLRKAMKGFGTDEKSIIQVLTKRSNEQRLRIALEFKTLYGKDLIS 302
           TV     F+  + A  L+KAMKGFG+DE++II+VL   + EQRL IA  FK  Y KDL++
Sbjct: 295 TVVAAENFDAGDCAEKLKKAMKGFGSDEEAIIEVLQSCNLEQRLAIAQSFKQQYDKDLVN 354

Query: 303 DIKSETSGKFEDLLIALLTPLPKFYAKELHEAM 401
           ++KSE SGKFED ++ALL P  +  A  LH AM
Sbjct: 355 ELKSELSGKFEDAIVALLLPPEQLDANALHGAM 387



 Score = 54.8 bits (126), Expect = 5e-08
 Identities = 32/103 (31%), Positives = 59/103 (57%), Gaps = 2/103 (1%)
 Frame = +3

Query: 156 EDAGVLRKAMKGFGTDEKSIIQVLT-KRSNEQRLR-IALEFKTLYGKDLISDIKSETSGK 329
           +D   L+KA++   +D+K+  +V+    S+E +L+ ++ E+   Y KDL+  +  + +  
Sbjct: 47  DDITKLQKAIEK--SDKKTATEVIVCNASDEGKLKKLSDEYNKRYEKDLVEQLDGKVADD 104

Query: 330 FEDLLIALLTPLPKFYAKELHEAMVGIGTDEGVLIEVMCTMSN 458
             + + +LL P  +   + L+ AM G+GT E  LIE +CT SN
Sbjct: 105 VHEAVTSLLLPATQADVRSLYYAMKGLGTKEAQLIETLCTRSN 147



 Score = 40.3 bits (90), Expect = 0.001
 Identities = 20/64 (31%), Positives = 39/64 (60%)
 Frame = +3

Query: 378 AKELHEAMVGIGTDEGVLIEVMCTMSNYEIHSIEQAYTAIYGKILEDDIRGDTSGNFNRL 557
           A++L +AM G G+DE  +IEV+ + +  +  +I Q++   Y K L ++++ + SG F   
Sbjct: 308 AEKLKKAMKGFGSDEEAIIEVLQSCNLEQRLAIAQSFKQQYDKDLVNELKSELSGKFEDA 367

Query: 558 MTSL 569
           + +L
Sbjct: 368 IVAL 371



 Score = 33.9 bits (74), Expect = 0.11
 Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 1/74 (1%)
 Frame = +3

Query: 135 VNPFNPREDAGVLRKA-MKGFGTDEKSIIQVLTKRSNEQRLRIALEFKTLYGKDLISDIK 311
           VN     EDA  L +A  K +GTDE    ++LT RS+ Q   +   ++ +   D++  I 
Sbjct: 398 VNEDQAYEDAKNLYEAGEKKWGTDESVFTKILTCRSDLQLRALYQAYQHVAKCDILETID 457

Query: 312 SETSGKFEDLLIAL 353
            E +G + D + A+
Sbjct: 458 DELTGDYHDAVKAI 471



 Score = 32.3 bits (70), Expect = 0.33
 Identities = 18/36 (50%), Positives = 20/36 (55%)
 Frame = +3

Query: 159 DAGVLRKAMKGFGTDEKSIIQVLTKRSNEQRLRIAL 266
           D   L  AMKG GT E  +I+ L  RSN   LR AL
Sbjct: 120 DVRSLYYAMKGLGTKEAQLIETLCTRSNTGDLRDAL 155



 Score = 28.7 bits (61), Expect(2) = 6e-22
 Identities = 17/57 (29%), Positives = 32/57 (56%), Gaps = 5/57 (8%)
 Frame = +3

Query: 378 AKELHEA-MVGIGTDEGVLIEVMCTMSNYEIHSIEQAYTAIYG----KILEDDIRGD 533
           AK L+EA     GTDE V  +++   S+ ++ ++ QAY  +      + ++D++ GD
Sbjct: 407 AKNLYEAGEKKWGTDESVFTKILTCRSDLQLRALYQAYQHVAKCDILETIDDELTGD 463


>SB_26806| Best HMM Match : Annexin (HMM E-Value=0)
          Length = 829

 Score = 93.9 bits (223), Expect = 1e-19
 Identities = 52/153 (33%), Positives = 88/153 (57%), Gaps = 2/153 (1%)
 Frame = +3

Query: 156 EDAGVLRKAMKGFGTDEKSIIQVLTKR-SNEQRLR-IALEFKTLYGKDLISDIKSETSGK 329
           +D   L+KA+    +D+K+   ++    S+E +L+ +  E+   Y KDL+  +  + +  
Sbjct: 444 DDITKLQKAIDK--SDKKTTTAIIVSNASDEGKLKKLNDEYNKRYKKDLVEQLDGKVAID 501

Query: 330 FEDLLIALLTPLPKFYAKELHEAMVGIGTDEGVLIEVMCTMSNYEIHSIEQAYTAIYGKI 509
             + + +LL P  K   + L+ AM G+GT E  LIE++CT SN EI  I+Q Y   YG+ 
Sbjct: 502 VHEAVTSLLLPATKADVRSLYYAMKGLGTKEAQLIEILCTRSNAEIQEIKQEYNKKYGRS 561

Query: 510 LEDDIRGDTSGNFNRLMTSLCVGNRSEDFTVDQ 608
           L DD++ +TSG+F  L+ +L  G+R E   V++
Sbjct: 562 LTDDMKSETSGDFENLLETLLKGSRDESTDVNK 594



 Score = 70.9 bits (166), Expect = 8e-13
 Identities = 53/169 (31%), Positives = 81/169 (47%), Gaps = 14/169 (8%)
 Frame = +3

Query: 153  REDAGVLRKAMKGFGTDEKSIIQVLTKRSNEQRLRIALEFKTLYGKDLISDIKSETSGKF 332
            + D   L  AMKG GT E  +I++L  RSN +   I  E+   YG+ L  D+KSETSG F
Sbjct: 515  KADVRSLYYAMKGLGTKEAQLIEILCTRSNAEIQEIKQEYNKKYGRSLTDDMKSETSGDF 574

Query: 333  EDLLIALL-------TPLPKFYAKELHEAMV--GI---GTDEGVLIEVMCTMSNYEIHSI 476
            E+LL  LL       T + K    +   A+V  G+   GTDE   I ++   S+  + ++
Sbjct: 575  ENLLETLLKGSRDESTDVNKELVTKDAAALVSAGVARWGTDEDQFITILSQRSSAHVQAV 634

Query: 477  EQAYTAIYGKI-LEDDIRGDTSGNF-NRLMTSLCVGNRSEDFTVDQNRA 617
               Y  + G + L D +R +  G+  + L+  +  G        D+  A
Sbjct: 635  LAEYKTLSGGVSLADTVRDEMKGDLRDALLVLISYGQDPSQAAADKLNA 683



 Score = 39.9 bits (89), Expect = 0.002
 Identities = 17/31 (54%), Positives = 23/31 (74%)
 Frame = +3

Query: 267 EFKTLYGKDLISDIKSETSGKFEDLLIALLT 359
           E++  YG  L  D+K ETSG FEDLL+AL++
Sbjct: 94  EYQKKYGCSLEDDVKEETSGDFEDLLVALMS 124



 Score = 38.3 bits (85), Expect = 0.005
 Identities = 35/115 (30%), Positives = 55/115 (47%), Gaps = 2/115 (1%)
 Frame = +3

Query: 231 KRSNEQRLRIALEFKTLYGKDLISDIKSETSGKFEDLLIALLTPLPKFYAKELHEAMVG- 407
           K+  E  ++ A++ K L  K L  D K +      D L   L        ++LHEA+   
Sbjct: 19  KKIKELVMKAAVDKKKL--KKLGDDYKKQYKQDLTDALDGKLE-------EDLHEAVAAM 69

Query: 408 -IGTDEGVLIEVMCTMSNYEIHSIEQAYTAIYGKILEDDIRGDTSGNFNRLMTSL 569
            +  +E     +   M N  I SI++ Y   YG  LEDD++ +TSG+F  L+ +L
Sbjct: 70  LLPGNEADARTLYFAMKN--IDSIKEEYQKKYGCSLEDDVKEETSGDFEDLLVAL 122



 Score = 31.5 bits (68), Expect = 0.57
 Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
 Frame = +3

Query: 156 EDAGVLRKA-MKGFGTDEKSIIQVLTKRSNEQRLRIALEFKTLYGKDLISD 305
           +DA  L  A +  +GT+E   I +LT+RS+     +  E++TL G   ++D
Sbjct: 772 QDAAALVSAGVARWGTEEDQFITILTQRSSAHVQAVLAEYRTLSGGVTLAD 822


>SB_35578| Best HMM Match : Annexin (HMM E-Value=1e-19)
          Length = 146

 Score = 91.5 bits (217), Expect = 5e-19
 Identities = 42/87 (48%), Positives = 59/87 (67%)
 Frame = +3

Query: 198 TDEKSIIQVLTKRSNEQRLRIALEFKTLYGKDLISDIKSETSGKFEDLLIALLTPLPKFY 377
           T+E  +I +L  RSN QR+ I   +KT+YGKDL++D+KSE SG  E+ L+A++ P   + 
Sbjct: 2   TNEAELIGILANRSNAQRVEIRKRYKTMYGKDLMNDLKSELSGNLEECLLAMMEPSVLYD 61

Query: 378 AKELHEAMVGIGTDEGVLIEVMCTMSN 458
           AK L   M G GTDE  LI+++CT SN
Sbjct: 62  AKCLRRGMRGAGTDEETLIDILCTRSN 88



 Score = 37.1 bits (82), Expect = 0.012
 Identities = 16/52 (30%), Positives = 29/52 (55%)
 Frame = +3

Query: 414 TDEGVLIEVMCTMSNYEIHSIEQAYTAIYGKILEDDIRGDTSGNFNRLMTSL 569
           T+E  LI ++   SN +   I + Y  +YGK L +D++ + SGN    + ++
Sbjct: 2   TNEAELIGILANRSNAQRVEIRKRYKTMYGKDLMNDLKSELSGNLEECLLAM 53



 Score = 36.7 bits (81), Expect = 0.015
 Identities = 15/29 (51%), Positives = 22/29 (75%)
 Frame = +3

Query: 159 DAGVLRKAMKGFGTDEKSIIQVLTKRSNE 245
           DA  LR+ M+G GTDE+++I +L  RSN+
Sbjct: 61  DAKCLRRGMRGAGTDEETLIDILCTRSNQ 89


>SB_7681| Best HMM Match : Annexin (HMM E-Value=0)
          Length = 426

 Score = 66.5 bits (155), Expect = 2e-11
 Identities = 46/153 (30%), Positives = 78/153 (50%), Gaps = 1/153 (0%)
 Frame = +3

Query: 114 SRPTVFPVNPFNPREDAGVLRKA-MKGFGTDEKSIIQVLTKRSNEQRLRIALEFKTLYGK 290
           +R T   V+     ++A  L KA  K +GTDE     VL  RS  Q      E+  +  +
Sbjct: 2   NRDTNMTVDMAKATKEAQDLYKAGEKKWGTDESRFNVVLASRSFPQLQATFNEYIKISQR 61

Query: 291 DLISDIKSETSGKFEDLLIALLTPLPKFYAKELHEAMVGIGTDEGVLIEVMCTMSNYEIH 470
           D+++ I  E SG  +  L     P  +++A  L ++M G GTD+ +LI V+ + S  ++ 
Sbjct: 62  DIMNSIDREMSGDLKAGLQCARNPA-EYFADRLWKSMKGAGTDDSLLIRVVVSRSEVDLV 120

Query: 471 SIEQAYTAIYGKILEDDIRGDTSGNFNRLMTSL 569
            I+ ++   Y K +   I GD SG++ +L+ +L
Sbjct: 121 EIKASFLQKYHKTVYKMIEGDCSGDYKKLLMAL 153



 Score = 47.6 bits (108), Expect = 8e-06
 Identities = 28/73 (38%), Positives = 41/73 (56%), Gaps = 1/73 (1%)
 Frame = +3

Query: 147 NPRED-AGVLRKAMKGFGTDEKSIIQVLTKRSNEQRLRIALEFKTLYGKDLISDIKSETS 323
           NP E  A  L K+MKG GTD+  +I+V+  RS    + I   F   Y K +   I+ + S
Sbjct: 84  NPAEYFADRLWKSMKGAGTDDSLLIRVVVSRSEVDLVEIKASFLQKYHKTVYKMIEGDCS 143

Query: 324 GKFEDLLIALLTP 362
           G ++ LL+AL +P
Sbjct: 144 GDYKKLLMALPSP 156


>SB_6006| Best HMM Match : Annexin (HMM E-Value=2.4e-25)
          Length = 803

 Score = 57.2 bits (132), Expect = 1e-08
 Identities = 31/106 (29%), Positives = 62/106 (58%), Gaps = 4/106 (3%)
 Frame = +3

Query: 153 REDAGVLRKAMKGFGTD--EKSIIQVLTKRSNEQRL--RIALEFKTLYGKDLISDIKSET 320
           +EDA  L +A++G  ++  + +II +L +  +E+    R+  ++K  + +D++  ++   
Sbjct: 347 KEDADELHQAIQGMVSEGNKDAIIDILARNCDERSKLDRLKDKYKDQHDQDILEALQPHL 406

Query: 321 SGKFEDLLIALLTPLPKFYAKELHEAMVGIGTDEGVLIEVMCTMSN 458
               +D + +  +    F AK LH+A+ G+GTDE +LIE++CT  N
Sbjct: 407 GDDVKDPVESFFSSSSAFDAKCLHDAIKGLGTDEDLLIEIICTRKN 452



 Score = 54.0 bits (124), Expect = 9e-08
 Identities = 30/87 (34%), Positives = 49/87 (56%), Gaps = 1/87 (1%)
 Frame = +3

Query: 201 DEKSIIQVLTKRSNEQRL-RIALEFKTLYGKDLISDIKSETSGKFEDLLIALLTPLPKFY 377
           D++ I+ +L + S + ++ ++  ++K LY KDL  ++KS    +    L +L        
Sbjct: 21  DKERIMGILGRTSEKDKMNKLEDKYKDLYKKDLNEELKSVLDEEIMKALESLAEEAAMKD 80

Query: 378 AKELHEAMVGIGTDEGVLIEVMCTMSN 458
           AK L+EA  G GTDE  LI ++CT SN
Sbjct: 81  AKTLYEATKGFGTDEDALISILCTRSN 107



 Score = 39.5 bits (88), Expect = 0.002
 Identities = 32/128 (25%), Positives = 62/128 (48%), Gaps = 3/128 (2%)
 Frame = +3

Query: 153 REDAGVLRKA-MKGFGTDEKSIIQVLTKRSNEQRLRIALEFKTLYGKDLISDIKSETSGK 329
           ++DA  L +A +  +GTDE + I+V T+RS  Q   +  E+K L   ++   I  E  G 
Sbjct: 123 KKDAKDLMEAGVASWGTDEGAFIRVFTQRSFTQISAMCAEYKKLTKVEIEESIDKEMDGD 182

Query: 330 FEDLLIAL--LTPLPKFYAKELHEAMVGIGTDEGVLIEVMCTMSNYEIHSIEQAYTAIYG 503
            +   + L  ++  P  +  +  +A V  G   G + +++  M+  +++ +  +Y     
Sbjct: 183 MQKAFLTLVKISRDPTGFQGDKLKAAVKDG-HLGAVAKILLPMNKAKLNEVSASYKKDTK 241

Query: 504 KILEDDIR 527
             L DDI+
Sbjct: 242 HELADDIQ 249



 Score = 36.7 bits (81), Expect = 0.015
 Identities = 16/30 (53%), Positives = 22/30 (73%)
 Frame = +3

Query: 156 EDAGVLRKAMKGFGTDEKSIIQVLTKRSNE 245
           +DA  L +A KGFGTDE ++I +L  RSN+
Sbjct: 79  KDAKTLYEATKGFGTDEDALISILCTRSNK 108



 Score = 32.7 bits (71), Expect = 0.25
 Identities = 15/41 (36%), Positives = 23/41 (56%)
 Frame = +3

Query: 159 DAGVLRKAMKGFGTDEKSIIQVLTKRSNEQRLRIALEFKTL 281
           DA  L  A+KG GTDE  +I+++  R N   + I++    L
Sbjct: 425 DAKCLHDAIKGLGTDEDLLIEIICTRKNTVSILISIVLSPL 465


>SB_32965| Best HMM Match : Kazal_1 (HMM E-Value=3.4e-19)
          Length = 69

 Score = 29.9 bits (64), Expect = 1.8
 Identities = 14/40 (35%), Positives = 23/40 (57%)
 Frame = -3

Query: 220 WIIDFSSVPKPFMALRRTPASSRGLNGFTGKTVGLDC*LG 101
           ++ DF ++P+    +R  PA +  + G  GKT G +C LG
Sbjct: 11  FLFDFKALPQVDKCVRPCPAINDPVCGTDGKTYGNECMLG 50


>SB_56182| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 525

 Score = 28.3 bits (60), Expect = 5.4
 Identities = 11/19 (57%), Positives = 13/19 (68%)
 Frame = +3

Query: 84  EGKIMFPNQQSRPTVFPVN 140
           EGKI FPN++ R  V P N
Sbjct: 419 EGKIQFPNEEFREIVLPCN 437


>SB_34906| Best HMM Match : Cadherin (HMM E-Value=0)
          Length = 3922

 Score = 27.9 bits (59), Expect = 7.1
 Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 5/83 (6%)
 Frame = +3

Query: 51   LISCFISKDIGEGKIMFPNQQSRPTVFPVNPFNPREDAGVLRKAMKGFGTDEKS-----I 215
            +I   I++D  +  I    ++ R +V     FN   + GVL  A K   T  KS     I
Sbjct: 1406 MIGAVIARDQDQDDI----EKVRYSVVSGTEFNVNTETGVLTVA-KDLSTGAKSEYSMEI 1460

Query: 216  IQVLTKRSNEQRLRIALEFKTLY 284
                + +SN+ R+R+ +E+K +Y
Sbjct: 1461 RATDSTKSNDARVRVNVEYKNMY 1483


  Database: nematostella
    Posted date:  Oct 22, 2007  1:22 PM
  Number of letters in database: 16,821,457
  Number of sequences in database:  59,808
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 19,056,762
Number of Sequences: 59808
Number of extensions: 388740
Number of successful extensions: 1273
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 1203
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1272
length of database: 16,821,457
effective HSP length: 79
effective length of database: 12,096,625
effective search space used: 1548368000
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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