Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= NRPG0400
(723 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein. 314 2e-85
CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein. 314 2e-85
BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein pr... 314 2e-85
BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein. 314 2e-85
AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitr... 314 2e-85
AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein. 314 2e-85
BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenas... 313 5e-85
CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein. 311 1e-84
AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitra... 309 8e-84
DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenas... 300 4e-81
X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase... 273 5e-73
U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase ... 272 8e-73
BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenas... 272 8e-73
BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenas... 272 8e-73
AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenas... 270 3e-72
AF197566-1|AAG43470.1| 127|Homo sapiens NADP+-specific isocitra... 128 3e-29
U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic NADP-d... 39 0.021
>CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 314 bits (771), Expect = 2e-85
Identities = 144/179 (80%), Positives = 157/179 (87%)
Frame = +3
Query: 24 QEYKKQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMT 203
++YK QFE IWYEHRLIDDMVA AMKSEGGF+WACKNYDGDVQSDSVAQGYGSLG+MT
Sbjct: 233 KQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMT 292
Query: 204 SVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDAL 383
SVL+CPDGKTVEAEAAHGTVTRH+R YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L
Sbjct: 293 SVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKEL 352
Query: 384 KNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYYETFEFMDKLAENLKVALGQ 560
FA LE+V IETIE+G MTKDLA CIKG+ NV+RSDY TFEFMDKL ENLK+ L Q
Sbjct: 353 AFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
>CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 314 bits (771), Expect = 2e-85
Identities = 144/179 (80%), Positives = 157/179 (87%)
Frame = +3
Query: 24 QEYKKQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMT 203
++YK QFE IWYEHRLIDDMVA AMKSEGGF+WACKNYDGDVQSDSVAQGYGSLG+MT
Sbjct: 233 KQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMT 292
Query: 204 SVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDAL 383
SVL+CPDGKTVEAEAAHGTVTRH+R YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L
Sbjct: 293 SVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKEL 352
Query: 384 KNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYYETFEFMDKLAENLKVALGQ 560
FA LE+V IETIE+G MTKDLA CIKG+ NV+RSDY TFEFMDKL ENLK+ L Q
Sbjct: 353 AFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
>BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein
protein.
Length = 414
Score = 314 bits (771), Expect = 2e-85
Identities = 144/179 (80%), Positives = 157/179 (87%)
Frame = +3
Query: 24 QEYKKQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMT 203
++YK QFE IWYEHRLIDDMVA AMKSEGGF+WACKNYDGDVQSDSVAQGYGSLG+MT
Sbjct: 233 KQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMT 292
Query: 204 SVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDAL 383
SVL+CPDGKTVEAEAAHGTVTRH+R YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L
Sbjct: 293 SVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKEL 352
Query: 384 KNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYYETFEFMDKLAENLKVALGQ 560
FA LE+V IETIE+G MTKDLA CIKG+ NV+RSDY TFEFMDKL ENLK+ L Q
Sbjct: 353 AFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
>BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein.
Length = 414
Score = 314 bits (771), Expect = 2e-85
Identities = 144/179 (80%), Positives = 157/179 (87%)
Frame = +3
Query: 24 QEYKKQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMT 203
++YK QFE IWYEHRLIDDMVA AMKSEGGF+WACKNYDGDVQSDSVAQGYGSLG+MT
Sbjct: 233 KQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMT 292
Query: 204 SVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDAL 383
SVL+CPDGKTVEAEAAHGTVTRH+R YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L
Sbjct: 293 SVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKEL 352
Query: 384 KNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYYETFEFMDKLAENLKVALGQ 560
FA LE+V IETIE+G MTKDLA CIKG+ NV+RSDY TFEFMDKL ENLK+ L Q
Sbjct: 353 AFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
>AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 314 bits (771), Expect = 2e-85
Identities = 144/179 (80%), Positives = 157/179 (87%)
Frame = +3
Query: 24 QEYKKQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMT 203
++YK QFE IWYEHRLIDDMVA AMKSEGGF+WACKNYDGDVQSDSVAQGYGSLG+MT
Sbjct: 233 KQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMT 292
Query: 204 SVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDAL 383
SVL+CPDGKTVEAEAAHGTVTRH+R YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L
Sbjct: 293 SVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKEL 352
Query: 384 KNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYYETFEFMDKLAENLKVALGQ 560
FA LE+V IETIE+G MTKDLA CIKG+ NV+RSDY TFEFMDKL ENLK+ L Q
Sbjct: 353 AFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
>AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein.
Length = 414
Score = 314 bits (771), Expect = 2e-85
Identities = 144/179 (80%), Positives = 157/179 (87%)
Frame = +3
Query: 24 QEYKKQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMT 203
++YK QFE IWYEHRLIDDMVA AMKSEGGF+WACKNYDGDVQSDSVAQGYGSLG+MT
Sbjct: 233 KQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMT 292
Query: 204 SVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDAL 383
SVL+CPDGKTVEAEAAHGTVTRH+R YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L
Sbjct: 293 SVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKEL 352
Query: 384 KNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYYETFEFMDKLAENLKVALGQ 560
FA LE+V IETIE+G MTKDLA CIKG+ NV+RSDY TFEFMDKL ENLK+ L Q
Sbjct: 353 AFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
>BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenase 1
(NADP+), soluble protein.
Length = 414
Score = 313 bits (768), Expect = 5e-85
Identities = 143/179 (79%), Positives = 157/179 (87%)
Frame = +3
Query: 24 QEYKKQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMT 203
++YK QFE IWYEHRLIDDMVA AMKSEGGF+WACKNYDGDVQSDSVAQGYGSLG+MT
Sbjct: 233 KQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMT 292
Query: 204 SVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDAL 383
SVL+CPDGKTVEAE+AHGTVTRH+R YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L
Sbjct: 293 SVLVCPDGKTVEAESAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKEL 352
Query: 384 KNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYYETFEFMDKLAENLKVALGQ 560
FA LE+V IETIE+G MTKDLA CIKG+ NV+RSDY TFEFMDKL ENLK+ L Q
Sbjct: 353 AFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
>CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 311 bits (764), Expect = 1e-84
Identities = 143/179 (79%), Positives = 156/179 (87%)
Frame = +3
Query: 24 QEYKKQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMT 203
++YK QFE IWYEHRLIDDMVA AMKSEGGF+WACKNYDGDVQSDSVAQGYGSLG+MT
Sbjct: 233 KQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMT 292
Query: 204 SVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDAL 383
SVL+CPDGKTVEAEAAHGTVTRH+R YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L
Sbjct: 293 SVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKEL 352
Query: 384 KNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYYETFEFMDKLAENLKVALGQ 560
FA LE+V IETIE+G MTK LA CIKG+ NV+RSDY TFEFMDKL ENLK+ L Q
Sbjct: 353 AFFANALEEVSIETIEAGFMTKGLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
>AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 309 bits (758), Expect = 8e-84
Identities = 142/179 (79%), Positives = 156/179 (87%)
Frame = +3
Query: 24 QEYKKQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMT 203
++YK QFE IWYEHRLIDDMVA AMKSEGGF+WACKNYDGDVQSDSVAQGYGSLG+MT
Sbjct: 233 KQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMT 292
Query: 204 SVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDAL 383
SVL+CPDGKTVEAEAAHGTVTRH+R YQ+G+ETSTN IASIFAWTRGL HRAKLDNN L
Sbjct: 293 SVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNLIASIFAWTRGLAHRAKLDNNKEL 352
Query: 384 KNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYYETFEFMDKLAENLKVALGQ 560
FA LE+V IETIE+G MTKDLA CI+G+ NV+RSDY TFEFMDKL ENLK+ L Q
Sbjct: 353 AFFANALEEVSIETIEAGFMTKDLAACIRGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
>DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenase 1
protein.
Length = 371
Score = 300 bits (736), Expect = 4e-81
Identities = 137/168 (81%), Positives = 149/168 (88%)
Frame = +3
Query: 24 QEYKKQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMT 203
++YK QFE IWYEHRLIDDMVA AMKSEGGF+WACKNYDGDVQSDSVAQGYGSLG+MT
Sbjct: 204 KQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMT 263
Query: 204 SVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDAL 383
SVL+CPDGKTVEAEAAHGTVTRH+R YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L
Sbjct: 264 SVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKEL 323
Query: 384 KNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYYETFEFMDK 527
FA LE+V IETIE+G MTKDLA CIKG+ NV+RSDY TFEFMDK
Sbjct: 324 AFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDK 371
>X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase
(NADP+) protein.
Length = 452
Score = 273 bits (669), Expect = 5e-73
Identities = 124/180 (68%), Positives = 148/180 (82%), Gaps = 1/180 (0%)
Frame = +3
Query: 24 QEYKKQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMT 203
+ YK F+ IWYEHRLIDDMVA +KS GGFVWACKNYDGDVQSD +AQG+GSLGLMT
Sbjct: 272 KHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMT 331
Query: 204 SVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDAL 383
SVL+CPDGKT+EAEAAHGTVTRH+R +Q+G+ TSTNPIASIFAWTRGL HR KLD N L
Sbjct: 332 SVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDL 391
Query: 384 KNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYY-ETFEFMDKLAENLKVALGQ 560
FA+ LEKVC+ET+ESG MTKDLA CI G++NVK ++++ T +F+D + NL ALG+
Sbjct: 392 IRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTMDFLDTIKSNLDRALGR 451
>U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase
protein.
Length = 419
Score = 272 bits (667), Expect = 8e-73
Identities = 124/180 (68%), Positives = 148/180 (82%), Gaps = 1/180 (0%)
Frame = +3
Query: 24 QEYKKQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMT 203
+ YK F+ IWYEHRLIDDMVA +KS GGFVWACKNYDGDVQSD +AQG+GSLGLMT
Sbjct: 239 KHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMT 298
Query: 204 SVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDAL 383
SVL+CPDGKT+EAEAAHGTVTRH+R +Q+G+ TSTNPIASIFAWTRGL HR KLD N L
Sbjct: 299 SVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDL 358
Query: 384 KNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYY-ETFEFMDKLAENLKVALGQ 560
FA+ LEKVC+ET+ESG MTKDLA CI G++NVK ++++ T +F+D + NL ALG+
Sbjct: 359 IRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGR 418
>BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 272 bits (667), Expect = 8e-73
Identities = 124/180 (68%), Positives = 148/180 (82%), Gaps = 1/180 (0%)
Frame = +3
Query: 24 QEYKKQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMT 203
+ YK F+ IWYEHRLIDDMVA +KS GGFVWACKNYDGDVQSD +AQG+GSLGLMT
Sbjct: 272 KHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMT 331
Query: 204 SVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDAL 383
SVL+CPDGKT+EAEAAHGTVTRH+R +Q+G+ TSTNPIASIFAWTRGL HR KLD N L
Sbjct: 332 SVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDL 391
Query: 384 KNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYY-ETFEFMDKLAENLKVALGQ 560
FA+ LEKVC+ET+ESG MTKDLA CI G++NVK ++++ T +F+D + NL ALG+
Sbjct: 392 IRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGR 451
>BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 272 bits (667), Expect = 8e-73
Identities = 124/180 (68%), Positives = 148/180 (82%), Gaps = 1/180 (0%)
Frame = +3
Query: 24 QEYKKQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMT 203
+ YK F+ IWYEHRLIDDMVA +KS GGFVWACKNYDGDVQSD +AQG+GSLGLMT
Sbjct: 272 KHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMT 331
Query: 204 SVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDAL 383
SVL+CPDGKT+EAEAAHGTVTRH+R +Q+G+ TSTNPIASIFAWTRGL HR KLD N L
Sbjct: 332 SVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDL 391
Query: 384 KNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYY-ETFEFMDKLAENLKVALGQ 560
FA+ LEKVC+ET+ESG MTKDLA CI G++NVK ++++ T +F+D + NL ALG+
Sbjct: 392 IRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGR 451
>AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial precursor variant protein.
Length = 452
Score = 270 bits (663), Expect = 3e-72
Identities = 123/180 (68%), Positives = 148/180 (82%), Gaps = 1/180 (0%)
Frame = +3
Query: 24 QEYKKQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMT 203
+ Y+ F+ IWYEHRLIDDMVA +KS GGFVWACKNYDGDVQSD +AQG+GSLGLMT
Sbjct: 272 KHYETDFDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMT 331
Query: 204 SVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDAL 383
SVL+CPDGKT+EAEAAHGTVTRH+R +Q+G+ TSTNPIASIFAWTRGL HR KLD N L
Sbjct: 332 SVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDL 391
Query: 384 KNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYY-ETFEFMDKLAENLKVALGQ 560
FA+ LEKVC+ET+ESG MTKDLA CI G++NVK ++++ T +F+D + NL ALG+
Sbjct: 392 IRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGR 451
>AF197566-1|AAG43470.1| 127|Homo sapiens NADP+-specific isocitrate
dehydrogenase protein.
Length = 127
Score = 128 bits (308), Expect = 3e-29
Identities = 61/89 (68%), Positives = 69/89 (77%)
Frame = +3
Query: 294 KETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKG 473
+E STNPIASIFAWTRGL RAK DNN L FA LE+VCIETIE+G MTKDLA CIKG
Sbjct: 1 QEISTNPIASIFAWTRGLALRAKTDNNKELAFFANALEEVCIETIEAGFMTKDLAACIKG 60
Query: 474 MNNVKRSDYYETFEFMDKLAENLKVALGQ 560
+ + + SDY TFEFM+KL ENLK+ L Q
Sbjct: 61 LPSAQCSDYLNTFEFMEKLGENLKIKLAQ 89
>U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic
NADP-dependent isocitrate dehydrogenase protein.
Length = 154
Score = 38.7 bits (86), Expect = 0.021
Identities = 15/21 (71%), Positives = 17/21 (80%)
Frame = +3
Query: 24 QEYKKQFEDAGIWYEHRLIDD 86
++YK QFE IWYEHRLIDD
Sbjct: 134 KQYKSQFEAQKIWYEHRLIDD 154
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 98,224,155
Number of Sequences: 237096
Number of extensions: 2020314
Number of successful extensions: 3064
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 2960
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3058
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8511181328
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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