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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= NRPG0323
         (650 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Z93242-1|CAI42724.1| 1630|Homo sapiens Nance-Horan syndrome (con...    34   0.51 
AY456993-1|AAS13456.1| 1473|Homo sapiens Nance-Horan syndrome pr...    34   0.51 
AY456992-1|AAS13455.1| 1474|Homo sapiens Nance-Horan syndrome pr...    34   0.51 
AY436752-1|AAR03104.1| 1630|Homo sapiens Nance-Horan syndrome pr...    34   0.51 
AL845433-1|CAI41241.1| 1630|Homo sapiens Nance-Horan syndrome (c...    34   0.51 
BC012780-1|AAH12780.1|  504|Homo sapiens C6orf111 protein protein.     33   0.88 
AL513550-4|CAI17194.1|  805|Homo sapiens RP11-98I9.2 protein.          33   0.88 
AK074628-1|BAC11098.1|  520|Homo sapiens protein ( Homo sapiens ...    33   0.88 
AK027898-1|BAB55440.1|  499|Homo sapiens protein ( Homo sapiens ...    33   0.88 
AF314186-1|AAL76165.1|  500|Homo sapiens SR rich protein protein.      33   0.88 
AF314184-1|AAL76163.1|  805|Homo sapiens SR rich protein protein.      33   0.88 
AY352048-1|AAR89465.1| 1800|Homo sapiens putative protein kinase...    32   1.5  
AY082340-1|AAL99253.1| 1800|Homo sapiens putative protein kinase...    32   1.5  
BC050328-1|AAH50328.2|  290|Homo sapiens neuroblastoma breakpoin...    31   4.7  
AF491813-1|AAM09558.1| 2113|Homo sapiens Down syndrome cell adhe...    31   4.7  
AF334384-1|AAL57166.1| 2053|Homo sapiens Down syndrome cell adhe...    31   4.7  
AF304305-1|AAN32614.1| 1842|Homo sapiens Down syndrome cell adhe...    31   4.7  
AF304304-1|AAN32613.1| 2053|Homo sapiens Down syndrome cell adhe...    31   4.7  
AB032958-1|BAA86446.2| 2092|Homo sapiens KIAA1132 protein protein.     31   4.7  
AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein.              30   6.2  
AK123607-1|BAC85660.1|  677|Homo sapiens protein ( Homo sapiens ...    30   8.2  

>Z93242-1|CAI42724.1| 1630|Homo sapiens Nance-Horan syndrome
            (congenital cataracts and dental anomalies) protein.
          Length = 1630

 Score = 33.9 bits (74), Expect = 0.51
 Identities = 42/167 (25%), Positives = 70/167 (41%), Gaps = 7/167 (4%)
 Frame = +1

Query: 169  QSEGPTVDMNAINPTLHKYNTAHLRGK-HDVINYDNSSKNQKEHQRFWTLPKRTAETNQL 345
            QS+ PT   +  N   H++  +    K    I+Y++   +        +  +  A     
Sbjct: 1305 QSDSPTRATDVSNQFKHQFVMSRHHDKVPGTISYESEITSVNSFPEKCSKQENIASGISA 1364

Query: 346  RPTSSN--LNQDPGQLSAGNSIKISPIDPRASRSFKSSTPSNKENVVDLSCKLLSPVKST 519
            +  S N    +  G +   +  + SP D          + +  E V       +SP K  
Sbjct: 1365 KSASDNSKAEETQGNVDEASLKESSPSDDSIISPLSEDSQAEAEGV------FVSPNKPR 1418

Query: 520  MTNEELYAVIHKSKKK-LNIKDAPE---RAESPALSNISLSPVSSET 648
             T E+L+AVIH+SK+K L  KD+ +   R++S A  + S S  SS T
Sbjct: 1419 -TTEDLFAVIHRSKRKVLGRKDSGDMSVRSKSRAPLSSSSSSASSIT 1464


>AY456993-1|AAS13456.1| 1473|Homo sapiens Nance-Horan syndrome protein
            isoform 2 protein.
          Length = 1473

 Score = 33.9 bits (74), Expect = 0.51
 Identities = 42/167 (25%), Positives = 70/167 (41%), Gaps = 7/167 (4%)
 Frame = +1

Query: 169  QSEGPTVDMNAINPTLHKYNTAHLRGK-HDVINYDNSSKNQKEHQRFWTLPKRTAETNQL 345
            QS+ PT   +  N   H++  +    K    I+Y++   +        +  +  A     
Sbjct: 1148 QSDSPTRATDVSNQFKHQFVMSRHHDKVPGTISYESEITSVNSFPEKCSKQENIASGISA 1207

Query: 346  RPTSSN--LNQDPGQLSAGNSIKISPIDPRASRSFKSSTPSNKENVVDLSCKLLSPVKST 519
            +  S N    +  G +   +  + SP D          + +  E V       +SP K  
Sbjct: 1208 KSASDNSKAEETQGNVDEASLKESSPSDDSIISPLSEDSQAEAEGV------FVSPNKPR 1261

Query: 520  MTNEELYAVIHKSKKK-LNIKDAPE---RAESPALSNISLSPVSSET 648
             T E+L+AVIH+SK+K L  KD+ +   R++S A  + S S  SS T
Sbjct: 1262 -TTEDLFAVIHRSKRKVLGRKDSGDMSVRSKSRAPLSSSSSSASSIT 1307


>AY456992-1|AAS13455.1| 1474|Homo sapiens Nance-Horan syndrome protein
            isoform 1 protein.
          Length = 1474

 Score = 33.9 bits (74), Expect = 0.51
 Identities = 42/167 (25%), Positives = 70/167 (41%), Gaps = 7/167 (4%)
 Frame = +1

Query: 169  QSEGPTVDMNAINPTLHKYNTAHLRGK-HDVINYDNSSKNQKEHQRFWTLPKRTAETNQL 345
            QS+ PT   +  N   H++  +    K    I+Y++   +        +  +  A     
Sbjct: 1149 QSDSPTRATDVSNQFKHQFVMSRHHDKVPGTISYESEITSVNSFPEKCSKQENIASGISA 1208

Query: 346  RPTSSN--LNQDPGQLSAGNSIKISPIDPRASRSFKSSTPSNKENVVDLSCKLLSPVKST 519
            +  S N    +  G +   +  + SP D          + +  E V       +SP K  
Sbjct: 1209 KSASDNSKAEETQGNVDEASLKESSPSDDSIISPLSEDSQAEAEGV------FVSPNKPR 1262

Query: 520  MTNEELYAVIHKSKKK-LNIKDAPE---RAESPALSNISLSPVSSET 648
             T E+L+AVIH+SK+K L  KD+ +   R++S A  + S S  SS T
Sbjct: 1263 -TTEDLFAVIHRSKRKVLGRKDSGDMSVRSKSRAPLSSSSSSASSIT 1308


>AY436752-1|AAR03104.1| 1630|Homo sapiens Nance-Horan syndrome protein
            protein.
          Length = 1630

 Score = 33.9 bits (74), Expect = 0.51
 Identities = 42/167 (25%), Positives = 70/167 (41%), Gaps = 7/167 (4%)
 Frame = +1

Query: 169  QSEGPTVDMNAINPTLHKYNTAHLRGK-HDVINYDNSSKNQKEHQRFWTLPKRTAETNQL 345
            QS+ PT   +  N   H++  +    K    I+Y++   +        +  +  A     
Sbjct: 1305 QSDSPTRATDVSNQFKHQFVMSRHHDKVPGTISYESEITSVNSFPEKCSKQENIASGISA 1364

Query: 346  RPTSSN--LNQDPGQLSAGNSIKISPIDPRASRSFKSSTPSNKENVVDLSCKLLSPVKST 519
            +  S N    +  G +   +  + SP D          + +  E V       +SP K  
Sbjct: 1365 KSASDNSKAEETQGNVDEASLKESSPSDDSIISPLSEDSQAEAEGV------FVSPNKPR 1418

Query: 520  MTNEELYAVIHKSKKK-LNIKDAPE---RAESPALSNISLSPVSSET 648
             T E+L+AVIH+SK+K L  KD+ +   R++S A  + S S  SS T
Sbjct: 1419 -TTEDLFAVIHRSKRKVLGRKDSGDMSVRSKSRAPLSSSSSSASSIT 1464


>AL845433-1|CAI41241.1| 1630|Homo sapiens Nance-Horan syndrome
            (congenital cataracts and dental anomalies) protein.
          Length = 1630

 Score = 33.9 bits (74), Expect = 0.51
 Identities = 42/167 (25%), Positives = 70/167 (41%), Gaps = 7/167 (4%)
 Frame = +1

Query: 169  QSEGPTVDMNAINPTLHKYNTAHLRGK-HDVINYDNSSKNQKEHQRFWTLPKRTAETNQL 345
            QS+ PT   +  N   H++  +    K    I+Y++   +        +  +  A     
Sbjct: 1305 QSDSPTRATDVSNQFKHQFVMSRHHDKVPGTISYESEITSVNSFPEKCSKQENIASGISA 1364

Query: 346  RPTSSN--LNQDPGQLSAGNSIKISPIDPRASRSFKSSTPSNKENVVDLSCKLLSPVKST 519
            +  S N    +  G +   +  + SP D          + +  E V       +SP K  
Sbjct: 1365 KSASDNSKAEETQGNVDEASLKESSPSDDSIISPLSEDSQAEAEGV------FVSPNKPR 1418

Query: 520  MTNEELYAVIHKSKKK-LNIKDAPE---RAESPALSNISLSPVSSET 648
             T E+L+AVIH+SK+K L  KD+ +   R++S A  + S S  SS T
Sbjct: 1419 -TTEDLFAVIHRSKRKVLGRKDSGDMSVRSKSRAPLSSSSSSASSIT 1464


>BC012780-1|AAH12780.1|  504|Homo sapiens C6orf111 protein protein.
          Length = 504

 Score = 33.1 bits (72), Expect = 0.88
 Identities = 27/95 (28%), Positives = 47/95 (49%), Gaps = 5/95 (5%)
 Frame = +1

Query: 355 SSNLNQDPGQLSAGNSIKI----SPIDPRASRSFKSSTPSNKENVVDLSCK-LLSPVKST 519
           S    +D   + A +S K+    SP+ P+   S    T   KE  + L  K LL+ +   
Sbjct: 290 SDEEEEDTENVEAASSGKVTRSPSPV-PQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLD 348

Query: 520 MTNEELYAVIHKSKKKLNIKDAPERAESPALSNIS 624
           +T+EE+Y V   + +K     A + A+S AL++++
Sbjct: 349 VTDEEIYYVAKDAHRKATKAPAKQLAQSSALASLT 383


>AL513550-4|CAI17194.1|  805|Homo sapiens RP11-98I9.2 protein.
          Length = 805

 Score = 33.1 bits (72), Expect = 0.88
 Identities = 27/95 (28%), Positives = 47/95 (49%), Gaps = 5/95 (5%)
 Frame = +1

Query: 355 SSNLNQDPGQLSAGNSIKI----SPIDPRASRSFKSSTPSNKENVVDLSCK-LLSPVKST 519
           S    +D   + A +S K+    SP+ P+   S    T   KE  + L  K LL+ +   
Sbjct: 290 SDEEEEDTENVEAASSGKVTRSPSPV-PQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLD 348

Query: 520 MTNEELYAVIHKSKKKLNIKDAPERAESPALSNIS 624
           +T+EE+Y V   + +K     A + A+S AL++++
Sbjct: 349 VTDEEIYYVAKDAHRKATKAPAKQLAQSSALASLT 383


>AK074628-1|BAC11098.1|  520|Homo sapiens protein ( Homo sapiens
           cDNA FLJ90147 fis, clone HEMBB1001847, weakly similar to
           NEUROGENIC PROTEIN BIG BRAIN. ).
          Length = 520

 Score = 33.1 bits (72), Expect = 0.88
 Identities = 27/95 (28%), Positives = 47/95 (49%), Gaps = 5/95 (5%)
 Frame = +1

Query: 355 SSNLNQDPGQLSAGNSIKI----SPIDPRASRSFKSSTPSNKENVVDLSCK-LLSPVKST 519
           S    +D   + A +S K+    SP+ P+   S    T   KE  + L  K LL+ +   
Sbjct: 290 SDEEEEDTENVEAASSGKVTRSPSPV-PQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLD 348

Query: 520 MTNEELYAVIHKSKKKLNIKDAPERAESPALSNIS 624
           +T+EE+Y V   + +K     A + A+S AL++++
Sbjct: 349 VTDEEIYYVAKDAHRKATKAPAKQLAQSSALASLT 383


>AK027898-1|BAB55440.1|  499|Homo sapiens protein ( Homo sapiens
           cDNA FLJ14992 fis, clone Y79AA1001805. ).
          Length = 499

 Score = 33.1 bits (72), Expect = 0.88
 Identities = 27/95 (28%), Positives = 47/95 (49%), Gaps = 5/95 (5%)
 Frame = +1

Query: 355 SSNLNQDPGQLSAGNSIKI----SPIDPRASRSFKSSTPSNKENVVDLSCK-LLSPVKST 519
           S    +D   + A +S K+    SP+ P+   S    T   KE  + L  K LL+ +   
Sbjct: 290 SDEEEEDTENVEAASSGKVTRSPSPV-PQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLD 348

Query: 520 MTNEELYAVIHKSKKKLNIKDAPERAESPALSNIS 624
           +T+EE+Y V   + +K     A + A+S AL++++
Sbjct: 349 VTDEEIYYVAKDAHRKATKAPAKQLAQSSALASLT 383


>AF314186-1|AAL76165.1|  500|Homo sapiens SR rich protein protein.
          Length = 500

 Score = 33.1 bits (72), Expect = 0.88
 Identities = 27/95 (28%), Positives = 47/95 (49%), Gaps = 5/95 (5%)
 Frame = +1

Query: 355 SSNLNQDPGQLSAGNSIKI----SPIDPRASRSFKSSTPSNKENVVDLSCK-LLSPVKST 519
           S    +D   + A +S K+    SP+ P+   S    T   KE  + L  K LL+ +   
Sbjct: 290 SDEEEEDTENVEAASSGKVTRSPSPV-PQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLD 348

Query: 520 MTNEELYAVIHKSKKKLNIKDAPERAESPALSNIS 624
           +T+EE+Y V   + +K     A + A+S AL++++
Sbjct: 349 VTDEEIYYVAKDAHRKATKAPAKQLAQSSALASLT 383


>AF314184-1|AAL76163.1|  805|Homo sapiens SR rich protein protein.
          Length = 805

 Score = 33.1 bits (72), Expect = 0.88
 Identities = 27/95 (28%), Positives = 47/95 (49%), Gaps = 5/95 (5%)
 Frame = +1

Query: 355 SSNLNQDPGQLSAGNSIKI----SPIDPRASRSFKSSTPSNKENVVDLSCK-LLSPVKST 519
           S    +D   + A +S K+    SP+ P+   S    T   KE  + L  K LL+ +   
Sbjct: 290 SDEEEEDTENVEAASSGKVTRSPSPV-PQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLD 348

Query: 520 MTNEELYAVIHKSKKKLNIKDAPERAESPALSNIS 624
           +T+EE+Y V   + +K     A + A+S AL++++
Sbjct: 349 VTDEEIYYVAKDAHRKATKAPAKQLAQSSALASLT 383


>AY352048-1|AAR89465.1| 1800|Homo sapiens putative protein kinase WNK3
            protein.
          Length = 1800

 Score = 32.3 bits (70), Expect = 1.5
 Identities = 17/70 (24%), Positives = 31/70 (44%)
 Frame = +1

Query: 322  RTAETNQLRPTSSNLNQDPGQLSAGNSIKISPIDPRASRSFKSSTPSNKENVVDLSCKLL 501
            +T +  +L+     L       +    I + P  PR  RSFKS   S  +++  +   ++
Sbjct: 1552 QTQQNKELQELYERLRSIKDSKTQSTEIPLPPASPRRPRSFKSKLRSRPQSLTHVDNGIV 1611

Query: 502  SPVKSTMTNE 531
            +  KS + NE
Sbjct: 1612 ATGKSCLINE 1621


>AY082340-1|AAL99253.1| 1800|Homo sapiens putative protein kinase WNK3
            protein.
          Length = 1800

 Score = 32.3 bits (70), Expect = 1.5
 Identities = 17/70 (24%), Positives = 31/70 (44%)
 Frame = +1

Query: 322  RTAETNQLRPTSSNLNQDPGQLSAGNSIKISPIDPRASRSFKSSTPSNKENVVDLSCKLL 501
            +T +  +L+     L       +    I + P  PR  RSFKS   S  +++  +   ++
Sbjct: 1552 QTQQNKELQELYERLRSIKDSKTQSTEIPLPPASPRRPRSFKSKLRSRPQSLTHVDNGIV 1611

Query: 502  SPVKSTMTNE 531
            +  KS + NE
Sbjct: 1612 ATGKSCLINE 1621


>BC050328-1|AAH50328.2|  290|Homo sapiens neuroblastoma breakpoint
           family, member 22 (pseudogene) protein.
          Length = 290

 Score = 30.7 bits (66), Expect = 4.7
 Identities = 20/54 (37%), Positives = 28/54 (51%)
 Frame = +2

Query: 356 PLISTRIQVNFLPVIP*KYHQ*IPERLDLSNHQLRPTKKTLLISVANCYRPSNQ 517
           PL S R ++N L +     +Q +  +L  SN Q R  K+  LIS A  Y  +NQ
Sbjct: 7   PLSSERAEMNILEI-----NQELRSQLAESNQQFRDLKEKFLISQATAYSLANQ 55


>AF491813-1|AAM09558.1| 2113|Homo sapiens Down syndrome cell adhesion
            molecule 2 protein.
          Length = 2113

 Score = 30.7 bits (66), Expect = 4.7
 Identities = 19/58 (32%), Positives = 30/58 (51%)
 Frame = +1

Query: 163  LVQSEGPTVDMNAINPTLHKYNTAHLRGKHDVINYDNSSKNQKEHQRFWTLPKRTAET 336
            L+QS GP +DM+ I P  +  +  +++  H       S++N+   Q  WTL K  A T
Sbjct: 1769 LIQSTGPLIDMSDIRPGTNPVSRKNVKSAH-------STRNRYSSQ--WTLTKCQAST 1817


>AF334384-1|AAL57166.1| 2053|Homo sapiens Down syndrome cell adhesion
            molecule DSCAML1 protein.
          Length = 2053

 Score = 30.7 bits (66), Expect = 4.7
 Identities = 19/58 (32%), Positives = 30/58 (51%)
 Frame = +1

Query: 163  LVQSEGPTVDMNAINPTLHKYNTAHLRGKHDVINYDNSSKNQKEHQRFWTLPKRTAET 336
            L+QS GP +DM+ I P  +  +  +++  H       S++N+   Q  WTL K  A T
Sbjct: 1709 LIQSTGPLIDMSDIRPGTNPVSRKNVKSAH-------STRNRYSSQ--WTLTKCQAST 1757


>AF304305-1|AAN32614.1| 1842|Homo sapiens Down syndrome cell adhesion
            molecule like-protein 1b protein.
          Length = 1842

 Score = 30.7 bits (66), Expect = 4.7
 Identities = 19/58 (32%), Positives = 30/58 (51%)
 Frame = +1

Query: 163  LVQSEGPTVDMNAINPTLHKYNTAHLRGKHDVINYDNSSKNQKEHQRFWTLPKRTAET 336
            L+QS GP +DM+ I P  +  +  +++  H       S++N+   Q  WTL K  A T
Sbjct: 1498 LIQSTGPLIDMSDIRPGTNPVSRKNVKSAH-------STRNRYSSQ--WTLTKCQAST 1546


>AF304304-1|AAN32613.1| 2053|Homo sapiens Down syndrome cell adhesion
            molecule like-protein 1a protein.
          Length = 2053

 Score = 30.7 bits (66), Expect = 4.7
 Identities = 19/58 (32%), Positives = 30/58 (51%)
 Frame = +1

Query: 163  LVQSEGPTVDMNAINPTLHKYNTAHLRGKHDVINYDNSSKNQKEHQRFWTLPKRTAET 336
            L+QS GP +DM+ I P  +  +  +++  H       S++N+   Q  WTL K  A T
Sbjct: 1709 LIQSTGPLIDMSDIRPGTNPVSRKNVKSAH-------STRNRYSSQ--WTLTKCQAST 1757


>AB032958-1|BAA86446.2| 2092|Homo sapiens KIAA1132 protein protein.
          Length = 2092

 Score = 30.7 bits (66), Expect = 4.7
 Identities = 19/58 (32%), Positives = 30/58 (51%)
 Frame = +1

Query: 163  LVQSEGPTVDMNAINPTLHKYNTAHLRGKHDVINYDNSSKNQKEHQRFWTLPKRTAET 336
            L+QS GP +DM+ I P  +  +  +++  H       S++N+   Q  WTL K  A T
Sbjct: 1748 LIQSTGPLIDMSDIRPGTNPVSRKNVKSAH-------STRNRYSSQ--WTLTKCQAST 1796


>AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein.
          Length = 2828

 Score = 30.3 bits (65), Expect = 6.2
 Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 4/72 (5%)
 Frame = +1

Query: 136 KACLNIPHNLVQSEGPTV---DMNAINPTLH-KYNTAHLRGKHDVINYDNSSKNQKEHQR 303
           KA   +  ++V+ EG +    + N     LH K     L+ K D IN D  +K  +   +
Sbjct: 686 KALSRVREDIVEDEGGSGMGDEENTSRRLLHPKDQEVFLKTKDDAINGDKKAKKGRRKLK 745

Query: 304 FWTLPKRTAETN 339
            W   ++  ETN
Sbjct: 746 LWKHSEKEPETN 757


>AK123607-1|BAC85660.1|  677|Homo sapiens protein ( Homo sapiens
           cDNA FLJ41613 fis, clone CTONG3002412, moderately
           similar to Human DOCK180 protein mRNA. ).
          Length = 677

 Score = 29.9 bits (64), Expect = 8.2
 Identities = 15/61 (24%), Positives = 33/61 (54%), Gaps = 2/61 (3%)
 Frame = +1

Query: 244 GKHDVINYDNSSKNQKEHQRFWTLP--KRTAETNQLRPTSSNLNQDPGQLSAGNSIKISP 417
           G+HD++ Y   +K  ++ + + TLP  K   E  +L+ + + +   P + S  +S +I+ 
Sbjct: 11  GRHDLVVYKGDNKKMEDAKFYLTLPGTKMEMEEKELQASKNLVTFTPSKDSTKDSFQIAT 70

Query: 418 I 420
           +
Sbjct: 71  L 71


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.311    0.128    0.366 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 84,219,668
Number of Sequences: 237096
Number of extensions: 1687874
Number of successful extensions: 2921
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 2863
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2920
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7253890590
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.2 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (21.8 bits)

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