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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= NRPG0290
         (653 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for ...   175   9e-44
M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolas...   175   9e-44
AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin hydro...   175   9e-44
AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein.             175   9e-44
AY358729-1|AAQ89091.1|  567|Homo sapiens KPVW3022 protein.            157   4e-38
BC101829-1|AAI01830.1|  469|Homo sapiens cytosolic beta-glucosid...   154   3e-37
AK222963-1|BAD96683.1|  469|Homo sapiens cytosolic beta-glucosid...   154   3e-37
AJ278964-1|CAC08178.1|  469|Homo sapiens cytosolic beta-glucosid...   154   3e-37
AF323990-1|AAL37305.1|  469|Homo sapiens cytosolic beta-glucosid...   154   3e-37
AB017913-1|BAB18741.1|  469|Homo sapiens cytosolic beta-glucosid...   154   3e-37
AF317840-1|AAG39217.1|  469|Homo sapiens cytosolic beta-glucosid...   153   4e-37
BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein.         153   5e-37
BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein.         153   5e-37
AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protei...   153   5e-37
Z92540-2|CAC94767.1|  273|Homo sapiens 179I15.1 (klotho) protein.     140   3e-33
AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein.              140   3e-33
AB009667-2|BAA24941.1|  549|Homo sapiens Klotho protein (KL) pro...   140   3e-33
AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) pro...   140   3e-33
AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein.              140   3e-33
BC109377-1|AAI09378.1|  162|Homo sapiens GBA3 protein protein.         93   1e-18
BC029362-1|AAH29362.1|  162|Homo sapiens GBA3 protein protein.         93   1e-18
BC070188-1|AAH70188.1|  162|Homo sapiens GBA3 protein protein.         92   2e-18
Z84483-1|CAC94773.1|  739|Homo sapiens 46H23.1 (Klotho) protein.       61   3e-09

>X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for
            lactase-phlorizin hydrolase LPH (EC 3.2.1.23-62). ).
          Length = 1927

 Score =  175 bits (427), Expect = 9e-44
 Identities = 75/144 (52%), Positives = 97/144 (67%)
 Frame = +1

Query: 214  FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKRD 393
            F ++F++GVS++A QIEGAW+ DGK  SIWD+  H     VKD +  D+A DSYH    D
Sbjct: 903  FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962

Query: 394  AEMVHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEILKYNITPMITIYHWD 573
              M+  L V  YRFS+SW RI PTG  + IN  G+ YYN LIN ++  NI PM+T++HWD
Sbjct: 963  LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 1022

Query: 574  LPQKLQDIGGWSNAHIVDYYTDYA 645
            LPQ LQDIGGW N  ++D +  YA
Sbjct: 1023 LPQALQDIGGWENPALIDLFDSYA 1046



 Score =  166 bits (404), Expect = 5e-41
 Identities = 77/147 (52%), Positives = 95/147 (64%)
 Frame = +1

Query: 211  KFPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKR 390
            +FPE FI+  ++AA QIEGAW  DGK  SIWD   H  P  V++ +  DVA DSYH    
Sbjct: 1376 RFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSH-TPLRVENDAIGDVACDSYHKIAE 1434

Query: 391  DAEMVHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEILKYNITPMITIYHW 570
            D   +  LGV  YRFS+SW RILP G T  INE G+ YY  LI+ +L  +I P +TIYHW
Sbjct: 1435 DLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHW 1494

Query: 571  DLPQKLQDIGGWSNAHIVDYYTDYAKI 651
            DLPQ LQD+GGW N  IV  + +YA +
Sbjct: 1495 DLPQTLQDVGGWENETIVQRFKEYADV 1521



 Score =  138 bits (333), Expect = 2e-32
 Identities = 65/145 (44%), Positives = 86/145 (59%), Gaps = 1/145 (0%)
 Frame = +1

Query: 214 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDG-SNADVASDSYHLYKR 390
           FPE F++G ST A  +EG W   G+  SIWD    + P    +G +  +VASDSYH    
Sbjct: 382 FPEGFLWGASTGAFNVEGGWAEGGRGVSIWDP---RRPLNTTEGQATLEVASDSYHKVAS 438

Query: 391 DAEMVHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEILKYNITPMITIYHW 570
           D  ++  L    Y+FS+SW RI P G  +  +  G+AYYN LI+ +    I PM T++HW
Sbjct: 439 DVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATLFHW 498

Query: 571 DLPQKLQDIGGWSNAHIVDYYTDYA 645
           DLPQ LQD GGW N  +VD + DYA
Sbjct: 499 DLPQALQDHGGWQNESVVDAFLDYA 523



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 16/59 (27%), Positives = 30/59 (50%)
 Frame = +1

Query: 403 VHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEILKYNITPMITIYHWDLP 579
           +H   +  Y+  +SW ++LP G T   +E  +  Y  L+  +    + PM+ ++H  LP
Sbjct: 79  LHASQITHYKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLP 137


>M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolase
            protein.
          Length = 1927

 Score =  175 bits (427), Expect = 9e-44
 Identities = 75/144 (52%), Positives = 97/144 (67%)
 Frame = +1

Query: 214  FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKRD 393
            F ++F++GVS++A QIEGAW+ DGK  SIWD+  H     VKD +  D+A DSYH    D
Sbjct: 903  FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962

Query: 394  AEMVHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEILKYNITPMITIYHWD 573
              M+  L V  YRFS+SW RI PTG  + IN  G+ YYN LIN ++  NI PM+T++HWD
Sbjct: 963  LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 1022

Query: 574  LPQKLQDIGGWSNAHIVDYYTDYA 645
            LPQ LQDIGGW N  ++D +  YA
Sbjct: 1023 LPQALQDIGGWENPALIDLFDSYA 1046



 Score =  166 bits (404), Expect = 5e-41
 Identities = 77/147 (52%), Positives = 95/147 (64%)
 Frame = +1

Query: 211  KFPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKR 390
            +FPE FI+  ++AA QIEGAW  DGK  SIWD   H  P  V++ +  DVA DSYH    
Sbjct: 1376 RFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSH-TPLRVENDAIGDVACDSYHKIAE 1434

Query: 391  DAEMVHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEILKYNITPMITIYHW 570
            D   +  LGV  YRFS+SW RILP G T  INE G+ YY  LI+ +L  +I P +TIYHW
Sbjct: 1435 DLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHW 1494

Query: 571  DLPQKLQDIGGWSNAHIVDYYTDYAKI 651
            DLPQ LQD+GGW N  IV  + +YA +
Sbjct: 1495 DLPQTLQDVGGWENETIVQRFKEYADV 1521



 Score =  138 bits (333), Expect = 2e-32
 Identities = 65/145 (44%), Positives = 86/145 (59%), Gaps = 1/145 (0%)
 Frame = +1

Query: 214 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDG-SNADVASDSYHLYKR 390
           FPE F++G ST A  +EG W   G+  SIWD    + P    +G +  +VASDSYH    
Sbjct: 382 FPEGFLWGASTGAFNVEGGWAEGGRGVSIWDP---RRPLNTTEGQATLEVASDSYHKVAS 438

Query: 391 DAEMVHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEILKYNITPMITIYHW 570
           D  ++  L    Y+FS+SW RI P G  +  +  G+AYYN LI+ +    I PM T++HW
Sbjct: 439 DVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATLFHW 498

Query: 571 DLPQKLQDIGGWSNAHIVDYYTDYA 645
           DLPQ LQD GGW N  +VD + DYA
Sbjct: 499 DLPQALQDHGGWQNESVVDAFLDYA 523



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 16/59 (27%), Positives = 30/59 (50%)
 Frame = +1

Query: 403 VHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEILKYNITPMITIYHWDLP 579
           +H   +  Y+  +SW ++LP G T   +E  +  Y  L+  +    + PM+ ++H  LP
Sbjct: 79  LHASQITHYKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLP 137


>AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin
           hydrolase-1 protein.
          Length = 1003

 Score =  175 bits (427), Expect = 9e-44
 Identities = 75/144 (52%), Positives = 97/144 (67%)
 Frame = +1

Query: 214 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKRD 393
           F ++F++GVS++A QIEGAW+ DGK  SIWD+  H     VKD +  D+A DSYH    D
Sbjct: 335 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 394

Query: 394 AEMVHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEILKYNITPMITIYHWD 573
             M+  L V  YRFS+SW RI PTG  + IN  G+ YYN LIN ++  NI PM+T++HWD
Sbjct: 395 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 454

Query: 574 LPQKLQDIGGWSNAHIVDYYTDYA 645
           LPQ LQDIGGW N  ++D +  YA
Sbjct: 455 LPQALQDIGGWENPALIDLFDSYA 478



 Score =  166 bits (404), Expect = 5e-41
 Identities = 77/147 (52%), Positives = 95/147 (64%)
 Frame = +1

Query: 211  KFPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKR 390
            +FPE FI+  ++AA QIEGAW  DGK  SIWD   H  P  V++ +  DVA DSYH    
Sbjct: 808  RFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSH-TPLRVENDAIGDVACDSYHKIAE 866

Query: 391  DAEMVHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEILKYNITPMITIYHW 570
            D   +  LGV  YRFS+SW RILP G T  INE G+ YY  LI+ +L  +I P +TIYHW
Sbjct: 867  DLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHW 926

Query: 571  DLPQKLQDIGGWSNAHIVDYYTDYAKI 651
            DLPQ LQD+GGW N  IV  + +YA +
Sbjct: 927  DLPQTLQDVGGWENETIVQRFKEYADV 953


>AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein.
          Length = 1927

 Score =  175 bits (427), Expect = 9e-44
 Identities = 75/144 (52%), Positives = 97/144 (67%)
 Frame = +1

Query: 214  FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKRD 393
            F ++F++GVS++A QIEGAW+ DGK  SIWD+  H     VKD +  D+A DSYH    D
Sbjct: 903  FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962

Query: 394  AEMVHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEILKYNITPMITIYHWD 573
              M+  L V  YRFS+SW RI PTG  + IN  G+ YYN LIN ++  NI PM+T++HWD
Sbjct: 963  LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 1022

Query: 574  LPQKLQDIGGWSNAHIVDYYTDYA 645
            LPQ LQDIGGW N  ++D +  YA
Sbjct: 1023 LPQALQDIGGWENPALIDLFDSYA 1046



 Score =  166 bits (404), Expect = 5e-41
 Identities = 77/147 (52%), Positives = 95/147 (64%)
 Frame = +1

Query: 211  KFPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKR 390
            +FPE FI+  ++AA QIEGAW  DGK  SIWD   H  P  V++ +  DVA DSYH    
Sbjct: 1376 RFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSH-TPLRVENDAIGDVACDSYHKIAE 1434

Query: 391  DAEMVHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEILKYNITPMITIYHW 570
            D   +  LGV  YRFS+SW RILP G T  INE G+ YY  LI+ +L  +I P +TIYHW
Sbjct: 1435 DLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHW 1494

Query: 571  DLPQKLQDIGGWSNAHIVDYYTDYAKI 651
            DLPQ LQD+GGW N  IV  + +YA +
Sbjct: 1495 DLPQTLQDVGGWENETIVQRFKEYADV 1521



 Score =  138 bits (333), Expect = 2e-32
 Identities = 65/145 (44%), Positives = 86/145 (59%), Gaps = 1/145 (0%)
 Frame = +1

Query: 214 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDG-SNADVASDSYHLYKR 390
           FPE F++G ST A  +EG W   G+  SIWD    + P    +G +  +VASDSYH    
Sbjct: 382 FPEGFLWGASTGAFNVEGGWAEGGRGVSIWDP---RRPLNTTEGQATLEVASDSYHKVAS 438

Query: 391 DAEMVHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEILKYNITPMITIYHW 570
           D  ++  L    Y+FS+SW RI P G  +  +  G+AYYN LI+ +    I PM T++HW
Sbjct: 439 DVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATLFHW 498

Query: 571 DLPQKLQDIGGWSNAHIVDYYTDYA 645
           DLPQ LQD GGW N  +VD + DYA
Sbjct: 499 DLPQALQDHGGWQNESVVDAFLDYA 523



 Score = 40.7 bits (91), Expect = 0.004
 Identities = 16/59 (27%), Positives = 30/59 (50%)
 Frame = +1

Query: 403 VHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEILKYNITPMITIYHWDLP 579
           +H   +  Y+  +SW ++LP G T   +E  +  Y  L+  +    + PM+ ++H  LP
Sbjct: 79  LHASQITHYKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLP 137


>AY358729-1|AAQ89091.1|  567|Homo sapiens KPVW3022 protein.
          Length = 567

 Score =  157 bits (380), Expect = 4e-38
 Identities = 70/148 (47%), Positives = 98/148 (66%), Gaps = 2/148 (1%)
 Frame = +1

Query: 214 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKRD 393
           FP  F +GV ++A Q EGAW+ DGK  SIWD   H     V     ADVA D Y+  + D
Sbjct: 37  FPLGFSWGVGSSAYQTEGAWDQDGKGPSIWDVFTHSGKGKVLGNETADVACDGYYKVQED 96

Query: 394 AEMVHELGVDTYRFSVSWPRILPTGL-TNEINELGIAYYNNLINEILKYNITPMITIYHW 570
             ++ EL V+ YRFS+SWPR+LPTG+   ++N+ GI +Y++LI+ +L  NITP++T++HW
Sbjct: 97  IILLRELHVNHYRFSLSWPRLLPTGIRAEQVNKKGIEFYSDLIDALLSSNITPIVTLHHW 156

Query: 571 DLPQKLQ-DIGGWSNAHIVDYYTDYAKI 651
           DLPQ LQ   GGW N  + +Y+ DYA +
Sbjct: 157 DLPQLLQVKYGGWQNVSMANYFRDYANL 184


>BC101829-1|AAI01830.1|  469|Homo sapiens cytosolic beta-glucosidase
           protein.
          Length = 469

 Score =  154 bits (373), Expect = 3e-37
 Identities = 65/145 (44%), Positives = 95/145 (65%)
 Frame = +1

Query: 214 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKRD 393
           FP  F +  +TAA Q+EG W+ DGK   +WD   H+  E V      DVA  SY L++ D
Sbjct: 3   FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62

Query: 394 AEMVHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEILKYNITPMITIYHWD 573
            + + +LG+  YRFS+SW R+LP G T  IN+ GI YYN +I+++LK  +TP++T+YH+D
Sbjct: 63  LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122

Query: 574 LPQKLQDIGGWSNAHIVDYYTDYAK 648
           LPQ L+D GGW +  I++ +  YA+
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQ 147


>AK222963-1|BAD96683.1|  469|Homo sapiens cytosolic beta-glucosidase
           variant protein.
          Length = 469

 Score =  154 bits (373), Expect = 3e-37
 Identities = 65/145 (44%), Positives = 95/145 (65%)
 Frame = +1

Query: 214 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKRD 393
           FP  F +  +TAA Q+EG W+ DGK   +WD   H+  E V      DVA  SY L++ D
Sbjct: 3   FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62

Query: 394 AEMVHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEILKYNITPMITIYHWD 573
            + + +LG+  YRFS+SW R+LP G T  IN+ GI YYN +I+++LK  +TP++T+YH+D
Sbjct: 63  LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122

Query: 574 LPQKLQDIGGWSNAHIVDYYTDYAK 648
           LPQ L+D GGW +  I++ +  YA+
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQ 147


>AJ278964-1|CAC08178.1|  469|Homo sapiens cytosolic beta-glucosidase
           protein.
          Length = 469

 Score =  154 bits (373), Expect = 3e-37
 Identities = 65/145 (44%), Positives = 95/145 (65%)
 Frame = +1

Query: 214 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKRD 393
           FP  F +  +TAA Q+EG W+ DGK   +WD   H+  E V      DVA  SY L++ D
Sbjct: 3   FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62

Query: 394 AEMVHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEILKYNITPMITIYHWD 573
            + + +LG+  YRFS+SW R+LP G T  IN+ GI YYN +I+++LK  +TP++T+YH+D
Sbjct: 63  LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122

Query: 574 LPQKLQDIGGWSNAHIVDYYTDYAK 648
           LPQ L+D GGW +  I++ +  YA+
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQ 147


>AF323990-1|AAL37305.1|  469|Homo sapiens cytosolic beta-glucosidase
           protein.
          Length = 469

 Score =  154 bits (373), Expect = 3e-37
 Identities = 65/145 (44%), Positives = 95/145 (65%)
 Frame = +1

Query: 214 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKRD 393
           FP  F +  +TAA Q+EG W+ DGK   +WD   H+  E V      DVA  SY L++ D
Sbjct: 3   FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62

Query: 394 AEMVHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEILKYNITPMITIYHWD 573
            + + +LG+  YRFS+SW R+LP G T  IN+ GI YYN +I+++LK  +TP++T+YH+D
Sbjct: 63  LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122

Query: 574 LPQKLQDIGGWSNAHIVDYYTDYAK 648
           LPQ L+D GGW +  I++ +  YA+
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQ 147


>AB017913-1|BAB18741.1|  469|Homo sapiens cytosolic
           beta-glucosidase-like protein-1 protein.
          Length = 469

 Score =  154 bits (373), Expect = 3e-37
 Identities = 65/145 (44%), Positives = 95/145 (65%)
 Frame = +1

Query: 214 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKRD 393
           FP  F +  +TAA Q+EG W+ DGK   +WD   H+  E V      DVA  SY L++ D
Sbjct: 3   FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62

Query: 394 AEMVHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEILKYNITPMITIYHWD 573
            + + +LG+  YRFS+SW R+LP G T  IN+ GI YYN +I+++LK  +TP++T+YH+D
Sbjct: 63  LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122

Query: 574 LPQKLQDIGGWSNAHIVDYYTDYAK 648
           LPQ L+D GGW +  I++ +  YA+
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQ 147


>AF317840-1|AAG39217.1|  469|Homo sapiens cytosolic beta-glucosidase
           protein.
          Length = 469

 Score =  153 bits (372), Expect = 4e-37
 Identities = 65/145 (44%), Positives = 95/145 (65%)
 Frame = +1

Query: 214 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKRD 393
           FP  F +  +TAA Q+EG W+ DGK   +WD   H+  E V      DVA  SY L++ D
Sbjct: 3   FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62

Query: 394 AEMVHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEILKYNITPMITIYHWD 573
            + + +LG+  YRFS+SW R+LP G T  IN+ GI YYN +I+++LK  +TP++T+YH+D
Sbjct: 63  LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122

Query: 574 LPQKLQDIGGWSNAHIVDYYTDYAK 648
           LPQ L+D GGW +  I++ +  YA+
Sbjct: 123 LPQTLEDQGGWWSEAIIESFDKYAQ 147


>BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein.
          Length = 1044

 Score =  153 bits (371), Expect = 5e-37
 Identities = 64/145 (44%), Positives = 96/145 (66%), Gaps = 1/145 (0%)
 Frame = +1

Query: 214 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKRD 393
           FP+NF +G+ T A Q+EG+W  DGK  SIWDH +H +   +K+ S+ + +SDSY   ++D
Sbjct: 81  FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTH---LKNVSSTNGSSDSYIFLEKD 137

Query: 394 AEMVHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEILKYNITPMITIYHWD 573
              +  +GV  Y+FS+SWPR+ P G+    N  G+ YY+ L++ ++  NI P++T+YHWD
Sbjct: 138 LSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWD 197

Query: 574 LPQKLQD-IGGWSNAHIVDYYTDYA 645
           LP  LQ+  GGW N  I+D + DYA
Sbjct: 198 LPLALQEKYGGWKNDTIIDIFNDYA 222



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 44/157 (28%), Positives = 79/157 (50%), Gaps = 12/157 (7%)
 Frame = +1

Query: 211 KFPENFIFGVSTAAAQIEGAWNVDGKSES---IWD----HLVHKNPEFVKDGSNADVASD 369
           +FP +F +GV+ +  + E   +    S+    +W+     L+H+  E V+  +     +D
Sbjct: 520 QFPCDFSWGVTESVLKPESVASSPQFSDPHLYVWNATGNRLLHR-VEGVRLKTRPAQCTD 578

Query: 370 SYHLYKRDAEMVHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEILKYNITP 549
             ++ K+  EM+  + V  YRF++ W  +LPTG  + +N   + YY  +++E LK  I+ 
Sbjct: 579 FVNI-KKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISA 637

Query: 550 MITIY-----HWDLPQKLQDIGGWSNAHIVDYYTDYA 645
           M+T+Y     H  LP+ L    GW N    + +  YA
Sbjct: 638 MVTLYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYA 674


>BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein.
          Length = 1044

 Score =  153 bits (371), Expect = 5e-37
 Identities = 64/145 (44%), Positives = 96/145 (66%), Gaps = 1/145 (0%)
 Frame = +1

Query: 214 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKRD 393
           FP+NF +G+ T A Q+EG+W  DGK  SIWDH +H +   +K+ S+ + +SDSY   ++D
Sbjct: 81  FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTH---LKNVSSTNGSSDSYIFLEKD 137

Query: 394 AEMVHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEILKYNITPMITIYHWD 573
              +  +GV  Y+FS+SWPR+ P G+    N  G+ YY+ L++ ++  NI P++T+YHWD
Sbjct: 138 LSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWD 197

Query: 574 LPQKLQD-IGGWSNAHIVDYYTDYA 645
           LP  LQ+  GGW N  I+D + DYA
Sbjct: 198 LPLALQEKYGGWKNDTIIDIFNDYA 222



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 44/157 (28%), Positives = 79/157 (50%), Gaps = 12/157 (7%)
 Frame = +1

Query: 211 KFPENFIFGVSTAAAQIEGAWNVDGKSES---IWD----HLVHKNPEFVKDGSNADVASD 369
           +FP +F +GV+ +  + E   +    S+    +W+     L+H+  E V+  +     +D
Sbjct: 520 QFPCDFSWGVTESVLKPESVASSPQFSDPHLYVWNATGNRLLHR-VEGVRLKTRPAQCTD 578

Query: 370 SYHLYKRDAEMVHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEILKYNITP 549
             ++ K+  EM+  + V  YRF++ W  +LPTG  + +N   + YY  +++E LK  I+ 
Sbjct: 579 FVNI-KKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISA 637

Query: 550 MITIY-----HWDLPQKLQDIGGWSNAHIVDYYTDYA 645
           M+T+Y     H  LP+ L    GW N    + +  YA
Sbjct: 638 MVTLYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYA 674


>AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protein
           protein.
          Length = 1044

 Score =  153 bits (371), Expect = 5e-37
 Identities = 64/145 (44%), Positives = 96/145 (66%), Gaps = 1/145 (0%)
 Frame = +1

Query: 214 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKRD 393
           FP+NF +G+ T A Q+EG+W  DGK  SIWDH +H +   +K+ S+ + +SDSY   ++D
Sbjct: 81  FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTH---LKNVSSTNGSSDSYIFLEKD 137

Query: 394 AEMVHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEILKYNITPMITIYHWD 573
              +  +GV  Y+FS+SWPR+ P G+    N  G+ YY+ L++ ++  NI P++T+YHWD
Sbjct: 138 LSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWD 197

Query: 574 LPQKLQD-IGGWSNAHIVDYYTDYA 645
           LP  LQ+  GGW N  I+D + DYA
Sbjct: 198 LPLALQEKYGGWKNDTIIDIFNDYA 222



 Score = 66.1 bits (154), Expect = 1e-10
 Identities = 44/157 (28%), Positives = 79/157 (50%), Gaps = 12/157 (7%)
 Frame = +1

Query: 211 KFPENFIFGVSTAAAQIEGAWNVDGKSES---IWD----HLVHKNPEFVKDGSNADVASD 369
           +FP +F +GV+ +  + E   +    S+    +W+     L+H+  E V+  +     +D
Sbjct: 520 QFPCDFSWGVTESVLKPESVASSPQFSDPHLYVWNATGNRLLHR-VEGVRLKTRPAQCTD 578

Query: 370 SYHLYKRDAEMVHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEILKYNITP 549
             ++ K+  EM+  + V  YRF++ W  +LPTG  + +N   + YY  +++E LK  I+ 
Sbjct: 579 FVNI-KKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISA 637

Query: 550 MITIY-----HWDLPQKLQDIGGWSNAHIVDYYTDYA 645
           M+T+Y     H  LP+ L    GW N    + +  YA
Sbjct: 638 MVTLYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYA 674


>Z92540-2|CAC94767.1|  273|Homo sapiens 179I15.1 (klotho) protein.
          Length = 273

 Score =  140 bits (340), Expect = 3e-33
 Identities = 69/162 (42%), Positives = 92/162 (56%), Gaps = 16/162 (9%)
 Frame = +1

Query: 214 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNA------------- 354
           FP+ F++ V +AA Q EG W   GK  SIWD   H       D  NA             
Sbjct: 61  FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPA 120

Query: 355 --DVASDSYHLYKRDAEMVHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEI 528
             DVASDSY+   RD E + ELGV  YRFS+SW R+LP G     N  G+ YY  L+  +
Sbjct: 121 TGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERL 180

Query: 529 LKYNITPMITIYHWDLPQKLQD-IGGWSNAHIVDYYTDYAKI 651
            +  + P++T+YHWDLPQ+LQD  GGW+N  + D++ DYA++
Sbjct: 181 RELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAEL 222


>AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein.
          Length = 1012

 Score =  140 bits (340), Expect = 3e-33
 Identities = 69/162 (42%), Positives = 92/162 (56%), Gaps = 16/162 (9%)
 Frame = +1

Query: 214 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNA------------- 354
           FP+ F++ V +AA Q EG W   GK  SIWD   H       D  NA             
Sbjct: 61  FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPA 120

Query: 355 --DVASDSYHLYKRDAEMVHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEI 528
             DVASDSY+   RD E + ELGV  YRFS+SW R+LP G     N  G+ YY  L+  +
Sbjct: 121 TGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERL 180

Query: 529 LKYNITPMITIYHWDLPQKLQD-IGGWSNAHIVDYYTDYAKI 651
            +  + P++T+YHWDLPQ+LQD  GGW+N  + D++ DYA++
Sbjct: 181 RELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAEL 222



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 39/156 (25%), Positives = 75/156 (48%), Gaps = 10/156 (6%)
 Frame = +1

Query: 214 FPENFIFGVSTAAAQIEGAWN-VDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHL--- 381
           FP +F +GV     Q++   +     +  +WD  VH +   +K          SY +   
Sbjct: 519 FPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIKVDGVVTKKRKSYCVDFA 576

Query: 382 -YKRDAEMVHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEILKYNITPMIT 558
             +    ++ E+ V  +RFS+ W  ILP G  +++N   + YY  + +E+++ NITP++ 
Sbjct: 577 AIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVA 636

Query: 559 IY-----HWDLPQKLQDIGGWSNAHIVDYYTDYAKI 651
           ++     +  LP+ L   G W N +    + +YA++
Sbjct: 637 LWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARL 672


>AB009667-2|BAA24941.1|  549|Homo sapiens Klotho protein (KL)
           protein.
          Length = 549

 Score =  140 bits (340), Expect = 3e-33
 Identities = 69/162 (42%), Positives = 92/162 (56%), Gaps = 16/162 (9%)
 Frame = +1

Query: 214 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNA------------- 354
           FP+ F++ V +AA Q EG W   GK  SIWD   H       D  NA             
Sbjct: 61  FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPA 120

Query: 355 --DVASDSYHLYKRDAEMVHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEI 528
             DVASDSY+   RD E + ELGV  YRFS+SW R+LP G     N  G+ YY  L+  +
Sbjct: 121 TGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERL 180

Query: 529 LKYNITPMITIYHWDLPQKLQD-IGGWSNAHIVDYYTDYAKI 651
            +  + P++T+YHWDLPQ+LQD  GGW+N  + D++ DYA++
Sbjct: 181 RELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAEL 222


>AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL)
           protein.
          Length = 1012

 Score =  140 bits (340), Expect = 3e-33
 Identities = 69/162 (42%), Positives = 92/162 (56%), Gaps = 16/162 (9%)
 Frame = +1

Query: 214 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNA------------- 354
           FP+ F++ V +AA Q EG W   GK  SIWD   H       D  NA             
Sbjct: 61  FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPA 120

Query: 355 --DVASDSYHLYKRDAEMVHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEI 528
             DVASDSY+   RD E + ELGV  YRFS+SW R+LP G     N  G+ YY  L+  +
Sbjct: 121 TGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERL 180

Query: 529 LKYNITPMITIYHWDLPQKLQD-IGGWSNAHIVDYYTDYAKI 651
            +  + P++T+YHWDLPQ+LQD  GGW+N  + D++ DYA++
Sbjct: 181 RELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAEL 222



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 39/156 (25%), Positives = 75/156 (48%), Gaps = 10/156 (6%)
 Frame = +1

Query: 214 FPENFIFGVSTAAAQIEGAWN-VDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHL--- 381
           FP +F +GV     Q++   +     +  +WD  VH +   +K          SY +   
Sbjct: 519 FPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIKVDGVVTKKRKSYCVDFA 576

Query: 382 -YKRDAEMVHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEILKYNITPMIT 558
             +    ++ E+ V  +RFS+ W  ILP G  +++N   + YY  + +E+++ NITP++ 
Sbjct: 577 AIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVA 636

Query: 559 IY-----HWDLPQKLQDIGGWSNAHIVDYYTDYAKI 651
           ++     +  LP+ L   G W N +    + +YA++
Sbjct: 637 LWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARL 672


>AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein.
          Length = 1012

 Score =  140 bits (340), Expect = 3e-33
 Identities = 69/162 (42%), Positives = 92/162 (56%), Gaps = 16/162 (9%)
 Frame = +1

Query: 214 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNA------------- 354
           FP+ F++ V +AA Q EG W   GK  SIWD   H       D  NA             
Sbjct: 61  FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPA 120

Query: 355 --DVASDSYHLYKRDAEMVHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEI 528
             DVASDSY+   RD E + ELGV  YRFS+SW R+LP G     N  G+ YY  L+  +
Sbjct: 121 TGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERL 180

Query: 529 LKYNITPMITIYHWDLPQKLQD-IGGWSNAHIVDYYTDYAKI 651
            +  + P++T+YHWDLPQ+LQD  GGW+N  + D++ DYA++
Sbjct: 181 RELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAEL 222



 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 39/156 (25%), Positives = 75/156 (48%), Gaps = 10/156 (6%)
 Frame = +1

Query: 214 FPENFIFGVSTAAAQIEGAWN-VDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHL--- 381
           FP +F +GV     Q++   +     +  +WD  VH +   +K          SY +   
Sbjct: 519 FPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIKVDGVVTKKRKSYCVDFA 576

Query: 382 -YKRDAEMVHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEILKYNITPMIT 558
             +    ++ E+ V  +RFS+ W  ILP G  +++N   + YY  + +E+++ NITP++ 
Sbjct: 577 AIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVA 636

Query: 559 IY-----HWDLPQKLQDIGGWSNAHIVDYYTDYAKI 651
           ++     +  LP+ L   G W N +    + +YA++
Sbjct: 637 LWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARL 672


>BC109377-1|AAI09378.1|  162|Homo sapiens GBA3 protein protein.
          Length = 162

 Score = 92.7 bits (220), Expect = 1e-18
 Identities = 41/95 (43%), Positives = 56/95 (58%)
 Frame = +1

Query: 214 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKRD 393
           FP  F +  +TAA Q+EG W+ DGK   +WD   H+  E V      DVA  SY L++ D
Sbjct: 3   FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62

Query: 394 AEMVHELGVDTYRFSVSWPRILPTGLTNEINELGI 498
            + + +LG+  YRFS+SW R+LP G T  IN+  I
Sbjct: 63  LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97


>BC029362-1|AAH29362.1|  162|Homo sapiens GBA3 protein protein.
          Length = 162

 Score = 92.7 bits (220), Expect = 1e-18
 Identities = 41/95 (43%), Positives = 56/95 (58%)
 Frame = +1

Query: 214 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKRD 393
           FP  F +  +TAA Q+EG W+ DGK   +WD   H+  E V      DVA  SY L++ D
Sbjct: 3   FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62

Query: 394 AEMVHELGVDTYRFSVSWPRILPTGLTNEINELGI 498
            + + +LG+  YRFS+SW R+LP G T  IN+  I
Sbjct: 63  LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97


>BC070188-1|AAH70188.1|  162|Homo sapiens GBA3 protein protein.
          Length = 162

 Score = 91.9 bits (218), Expect = 2e-18
 Identities = 41/95 (43%), Positives = 56/95 (58%)
 Frame = +1

Query: 214 FPENFIFGVSTAAAQIEGAWNVDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHLYKRD 393
           FP  F +  +TAA Q+EG W+ DGK   +WD   H+  E V      DVA  SY L++ D
Sbjct: 3   FPAGFGWAAATAAYQVEGGWDADGKGLCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62

Query: 394 AEMVHELGVDTYRFSVSWPRILPTGLTNEINELGI 498
            + + +LG+  YRFS+SW R+LP G T  IN+  I
Sbjct: 63  LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97


>Z84483-1|CAC94773.1|  739|Homo sapiens 46H23.1 (Klotho) protein.
          Length = 739

 Score = 61.3 bits (142), Expect = 3e-09
 Identities = 39/156 (25%), Positives = 75/156 (48%), Gaps = 10/156 (6%)
 Frame = +1

Query: 214 FPENFIFGVSTAAAQIEGAWN-VDGKSESIWDHLVHKNPEFVKDGSNADVASDSYHL--- 381
           FP +F +GV     Q++   +     +  +WD  VH +   +K          SY +   
Sbjct: 246 FPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIKVDGVVTKKRKSYCVDFA 303

Query: 382 -YKRDAEMVHELGVDTYRFSVSWPRILPTGLTNEINELGIAYYNNLINEILKYNITPMIT 558
             +    ++ E+ V  +RFS+ W  ILP G  +++N   + YY  + +E+++ NITP++ 
Sbjct: 304 AIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVA 363

Query: 559 IY-----HWDLPQKLQDIGGWSNAHIVDYYTDYAKI 651
           ++     +  LP+ L   G W N +    + +YA++
Sbjct: 364 LWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARL 399


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 92,495,788
Number of Sequences: 237096
Number of extensions: 1874159
Number of successful extensions: 6990
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 6833
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6963
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7310122300
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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