Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= NRPG0246
(621 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P41572 Cluster: 6-phosphogluconate dehydrogenase, decar... 280 2e-74
UniRef50_P52209 Cluster: 6-phosphogluconate dehydrogenase, decar... 278 9e-74
UniRef50_Q17761 Cluster: 6-phosphogluconate dehydrogenase, decar... 258 6e-68
UniRef50_Q64V77 Cluster: 6-phosphogluconate dehydrogenase, decar... 184 2e-45
UniRef50_P80859 Cluster: 6-phosphogluconate dehydrogenase, decar... 182 6e-45
UniRef50_P21577 Cluster: 6-phosphogluconate dehydrogenase, decar... 176 3e-43
UniRef50_P52208 Cluster: 6-phosphogluconate dehydrogenase, decar... 172 5e-42
UniRef50_A5K3L2 Cluster: 6-phosphogluconate dehydrogenase, decar... 160 2e-38
UniRef50_Q5HP42 Cluster: 6-phosphogluconate dehydrogenase, decar... 158 9e-38
UniRef50_Q836Q9 Cluster: 6-phosphogluconate dehydrogenase, decar... 155 8e-37
UniRef50_Q1DDR1 Cluster: 6-phosphogluconate dehydrogenase, decar... 154 1e-36
UniRef50_Q92P61 Cluster: 6-phosphogluconate dehydrogenase, decar... 153 2e-36
UniRef50_P37754 Cluster: 6-phosphogluconate dehydrogenase, decar... 153 2e-36
UniRef50_P31072 Cluster: 6-phosphogluconate dehydrogenase, decar... 150 3e-35
UniRef50_Q3J9H5 Cluster: 6-phosphogluconate dehydrogenase, decar... 147 2e-34
UniRef50_Q660W3 Cluster: 6-phosphogluconate dehydrogenase, decar... 146 3e-34
UniRef50_Q5FHQ8 Cluster: 6-phosphogluconate dehydrogenase, decar... 146 3e-34
UniRef50_A7BAU3 Cluster: Putative uncharacterized protein; n=1; ... 146 3e-34
UniRef50_Q68Y99 Cluster: 6-phosphogluconate dehydrogenase, decar... 146 3e-34
UniRef50_A2GAV3 Cluster: 6-phosphogluconate dehydrogenase, decar... 143 3e-33
UniRef50_A6ELE2 Cluster: 6-phosphogluconate dehydrogenase, decar... 141 1e-32
UniRef50_Q8CX65 Cluster: 6-phosphogluconate dehydrogenase, decar... 133 3e-30
UniRef50_Q7TZG1 Cluster: 6-phosphogluconate dehydrogenase, decar... 132 6e-30
UniRef50_O32911 Cluster: 6-phosphogluconate dehydrogenase, decar... 131 1e-29
UniRef50_Q5IWZ8 Cluster: Plastid 6-phosphogluconate 2-dehydrogen... 130 3e-29
UniRef50_Q11V91 Cluster: 6-phosphogluconate dehydrogenase, decar... 129 5e-29
UniRef50_A6W129 Cluster: 6-phosphogluconate dehydrogenase, decar... 126 6e-28
UniRef50_Q8SRX1 Cluster: 6-PHOSPHOGLUCONATE DEHYDROGENASE; n=1; ... 122 9e-27
UniRef50_A5JEL6 Cluster: 6-phosphogluconate dehydrogenase, decar... 117 3e-25
UniRef50_UPI000050FFB4 Cluster: COG0362: 6-phosphogluconate dehy... 114 1e-24
UniRef50_A6PJ87 Cluster: 6-phosphogluconate dehydrogenase, decar... 112 6e-24
UniRef50_A0Y665 Cluster: 6-phosphogluconate dehydrogenase; n=3; ... 110 3e-23
UniRef50_Q9K9H3 Cluster: 6-phosphogluconate dehydrogenase; n=7; ... 105 9e-22
UniRef50_Q7QWR3 Cluster: GLP_26_8052_6637; n=1; Giardia lamblia ... 103 3e-21
UniRef50_Q4UGE1 Cluster: 6-phosphogluconate dehydrogenase, putat... 100 3e-20
UniRef50_A7AQE8 Cluster: 6-phosphogluconate dehydrogenase, putat... 98 2e-19
UniRef50_P54448 Cluster: Uncharacterized protein yqeC; n=13; Bac... 96 7e-19
UniRef50_Q9CDN4 Cluster: 6-phosphogluconate dehydrogenase; n=12;... 91 2e-17
UniRef50_Q6N3Q8 Cluster: 6-phosphogluconate dehydrogenase; n=57;... 91 3e-17
UniRef50_A0PKN6 Cluster: 6-phosphogluconate dehydrogenase, decar... 89 8e-17
UniRef50_Q1IK90 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 86 7e-16
UniRef50_Q82ZC2 Cluster: 6-phosphogluconate dehydrogenase family... 85 2e-15
UniRef50_Q9RU02 Cluster: 6-phosphogluconate dehydrogenase; n=24;... 82 9e-15
UniRef50_O66788 Cluster: 6-phosphogluconate dehydrogenase; n=2; ... 82 1e-14
UniRef50_Q7SCJ4 Cluster: Putative uncharacterized protein NCU008... 79 8e-14
UniRef50_Q0W2D7 Cluster: Putative 6-phosphogluconate dehydrogena... 76 6e-13
UniRef50_Q2LGT9 Cluster: 6-phosphogluconate dehydrogenase; n=6; ... 76 8e-13
UniRef50_Q0V6D4 Cluster: Putative uncharacterized protein; n=1; ... 75 1e-12
UniRef50_A7QND8 Cluster: Chromosome chr2 scaffold_132, whole gen... 72 1e-11
UniRef50_Q0SAG5 Cluster: Phosphogluconate dehydrogenase; n=23; A... 71 2e-11
UniRef50_A2Y8G5 Cluster: Putative uncharacterized protein; n=1; ... 69 7e-11
UniRef50_Q1NQF2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 66 5e-10
UniRef50_A3PSD9 Cluster: 6-phosphogluconate dehydrogenase, decar... 66 8e-10
UniRef50_A6SUL3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 61 2e-08
UniRef50_Q3DYV4 Cluster: NADP oxidoreductase, coenzyme F420-depe... 59 1e-07
UniRef50_O66454 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 57 3e-07
UniRef50_Q05FV1 Cluster: 6-phosphogluconate dehydrogenase; n=1; ... 57 3e-07
UniRef50_A5LYV4 Cluster: 6-phosphogluconate dehydrogenase; n=1; ... 57 3e-07
UniRef50_A7R419 Cluster: Chromosome undetermined scaffold_607, w... 57 3e-07
UniRef50_A7ES77 Cluster: Putative uncharacterized protein; n=1; ... 55 2e-06
UniRef50_Q41DK0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 53 5e-06
UniRef50_Q97XZ7 Cluster: Oxidoreductase; n=6; Thermoprotei|Rep: ... 53 5e-06
UniRef50_A4IN46 Cluster: 3-hydroxyisobutyrate dehydrogenase-like... 51 2e-05
UniRef50_A2Y8G6 Cluster: 6-phosphogluconate dehydrogenase, decar... 50 3e-05
UniRef50_Q18X68 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 48 1e-04
UniRef50_Q73P00 Cluster: 3-hydroxyacid dehydrogenase family prot... 48 2e-04
UniRef50_Q47AR2 Cluster: NADP oxidoreductase, coenzyme F420-depe... 48 2e-04
UniRef50_Q0F1Y7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 48 2e-04
UniRef50_Q97ZE5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4... 48 2e-04
UniRef50_A4SWE8 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 47 3e-04
UniRef50_P77161 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 47 3e-04
UniRef50_Q67QX0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 47 4e-04
UniRef50_Q03UI4 Cluster: 3-hydroxyisobutyrate dehydrogenase rela... 47 4e-04
UniRef50_Q8UBW3 Cluster: Oxidoredutase; n=1; Agrobacterium tumef... 46 6e-04
UniRef50_Q6UCZ9 Cluster: Predicted oxidoreductase; n=2; environm... 46 6e-04
UniRef50_A6NVP0 Cluster: Putative uncharacterized protein; n=1; ... 46 6e-04
UniRef50_A3X9R7 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 46 7e-04
UniRef50_Q7VYY0 Cluster: Putative oxidoreductase; n=4; Bordetell... 46 0.001
UniRef50_A1UP64 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 46 0.001
UniRef50_Q5L168 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 45 0.001
UniRef50_A6P2M7 Cluster: Putative uncharacterized protein; n=2; ... 45 0.001
UniRef50_Q606G9 Cluster: Oxidoreductase, Gfo/Idh/MocA family; n=... 45 0.002
UniRef50_Q1AVA4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 45 0.002
UniRef50_Q92D17 Cluster: Lin1004 protein; n=10; Bacilli|Rep: Lin... 44 0.002
UniRef50_Q89M84 Cluster: Blr4309 protein; n=6; Bradyrhizobiaceae... 44 0.002
UniRef50_Q629W3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 44 0.002
UniRef50_A6LT11 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 44 0.002
UniRef50_Q8F4I7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4... 44 0.004
UniRef50_Q89R44 Cluster: Oxidoreductase; n=23; Bacteria|Rep: Oxi... 44 0.004
UniRef50_Q4FMJ3 Cluster: 6-phosphogluconate dehydrogenase; n=2; ... 44 0.004
UniRef50_A5V0D4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 44 0.004
UniRef50_A7IE35 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 43 0.007
UniRef50_Q9K9L1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 42 0.009
UniRef50_Q5WBB8 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 42 0.009
UniRef50_A5GPC0 Cluster: Hydroxyacid dehydrogenase/reductase fam... 42 0.009
UniRef50_A5BFV6 Cluster: Putative uncharacterized protein; n=1; ... 42 0.009
UniRef50_A6EH53 Cluster: Putative uncharacterized protein; n=1; ... 42 0.012
UniRef50_A0K0Z6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 42 0.012
UniRef50_UPI0000D56743 Cluster: PREDICTED: similar to 3-hydroxyi... 41 0.021
UniRef50_Q183P5 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 41 0.021
UniRef50_Q12CU4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 41 0.021
UniRef50_A6RYG0 Cluster: Putative uncharacterized protein; n=1; ... 41 0.021
UniRef50_O34948 Cluster: Uncharacterized oxidoreductase ykwC; n=... 41 0.021
UniRef50_Q0QLF5 Cluster: 2-hydroxymethyl glutarate dehydrogenase... 41 0.027
UniRef50_P31937 Cluster: 3-hydroxyisobutyrate dehydrogenase, mit... 41 0.027
UniRef50_Q98K09 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 40 0.036
UniRef50_Q830A7 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 40 0.036
UniRef50_A7PEG7 Cluster: Chromosome chr11 scaffold_13, whole gen... 40 0.036
UniRef50_Q0U6Q6 Cluster: Putative uncharacterized protein; n=5; ... 40 0.036
UniRef50_A7DSF1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 40 0.036
UniRef50_Q55702 Cluster: Uncharacterized oxidoreductase slr0229;... 40 0.036
UniRef50_Q0BTJ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 40 0.048
UniRef50_A5FVG0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 40 0.048
UniRef50_A4FKN9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 40 0.048
UniRef50_A0G5G5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 40 0.048
UniRef50_Q7NWA9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 40 0.063
UniRef50_Q01ZG6 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 40 0.063
UniRef50_A7JGH8 Cluster: Predicted protein; n=1; Francisella tul... 40 0.063
UniRef50_A3I4V2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 40 0.063
UniRef50_Q1QWU9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 39 0.084
UniRef50_A6LNV2 Cluster: Ribonuclease, Rne/Rng family; n=1; Ther... 39 0.084
UniRef50_Q1N6I0 Cluster: Putative oxidoreductase protein; n=1; O... 39 0.11
UniRef50_A3WAC4 Cluster: Dehydrogenase; n=4; Bacteria|Rep: Dehyd... 38 0.15
UniRef50_A3H5R1 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 38 0.15
UniRef50_Q39KK8 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 38 0.19
UniRef50_A1SIN3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 38 0.19
UniRef50_Q94B07 Cluster: Gamma hydroxybutyrate dehydrogenase; n=... 38 0.19
UniRef50_Q4Q7T9 Cluster: 2-hydroxy-3-oxopropionate reductase, pu... 38 0.19
UniRef50_Q6F842 Cluster: Putative 3-hydroxyisobutyrate dehydroge... 38 0.26
UniRef50_Q2JEV5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 38 0.26
UniRef50_A0UF54 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 38 0.26
UniRef50_UPI00015B4B33 Cluster: PREDICTED: similar to 3-hydroxyi... 37 0.34
UniRef50_Q13LQ9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 37 0.34
UniRef50_Q0SBQ9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 37 0.34
UniRef50_Q4ZQL5 Cluster: 3-hydroxyisobutyrate dehydrogenase prec... 37 0.45
UniRef50_Q1INE9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 36 0.59
UniRef50_A7H7Z5 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 36 0.59
UniRef50_A6VLT0 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 36 0.59
UniRef50_A4ECY9 Cluster: Putative uncharacterized protein; n=1; ... 36 0.59
UniRef50_A6GTB5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 36 0.78
UniRef50_A0LDJ3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 36 0.78
UniRef50_Q1EPJ1 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 36 0.78
UniRef50_UPI0000EBE4FC Cluster: PREDICTED: hypothetical protein;... 36 1.0
UniRef50_A5WG80 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 36 1.0
UniRef50_Q49A26 Cluster: Cytokine-like nuclear factor n-pac; n=4... 36 1.0
UniRef50_Q89HA0 Cluster: Oxidoreductase; n=1; Bradyrhizobium jap... 35 1.4
UniRef50_Q0EVH7 Cluster: Glutamyl-tRNA reductase; n=1; Thermoana... 35 1.4
UniRef50_Q6D9X4 Cluster: Putative 2-hydroxy-3-oxopropionate redu... 35 1.8
UniRef50_Q2JNP7 Cluster: Prephenate dehydrogenase; n=1; Synechoc... 35 1.8
UniRef50_Q01QM2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 35 1.8
UniRef50_A6F020 Cluster: Putative uncharacterized protein; n=1; ... 35 1.8
UniRef50_Q0VIN9 Cluster: AROM polypeptide; n=2; Tetrahymena ther... 35 1.8
UniRef50_A0NE61 Cluster: ENSANGP00000030787; n=1; Anopheles gamb... 35 1.8
UniRef50_Q8TT25 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 35 1.8
UniRef50_Q9JYH6 Cluster: 3-hydroxyacid dehydrogenase; n=5; Prote... 34 2.4
UniRef50_Q39FA8 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 34 2.4
UniRef50_Q392H4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 34 2.4
UniRef50_Q19TN0 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 34 2.4
UniRef50_A6LJ59 Cluster: NAD/NADP octopine/nopaline dehydrogenas... 34 2.4
UniRef50_Q84VC8 Cluster: Gamma hydroxybutyrate dehydrogenase-lik... 34 2.4
UniRef50_Q971W0 Cluster: Putative HTH-type transcriptional regul... 34 2.4
UniRef50_P0ABQ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 34 2.4
UniRef50_UPI0000E46E06 Cluster: PREDICTED: similar to MGC107852 ... 34 3.1
UniRef50_Q89RT2 Cluster: Bll2680 protein; n=1; Bradyrhizobium ja... 34 3.1
UniRef50_Q5LQR0 Cluster: 6-phosphogluconate dehydrogenase domain... 34 3.1
UniRef50_Q2JSE7 Cluster: Prephenate dehydrogenase; n=6; Cyanobac... 34 3.1
UniRef50_Q21ZN3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 34 3.1
UniRef50_Q1GJB9 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 34 3.1
UniRef50_UPI000155DAA0 Cluster: PREDICTED: similar to Transmembr... 33 4.2
UniRef50_Q98I20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 33 4.2
UniRef50_Q3W9W7 Cluster: 6-phosphogluconate dehydrogenase, NAD b... 33 4.2
UniRef50_Q0S5S3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 33 4.2
UniRef50_A0G5F9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 33 4.2
UniRef50_Q8RB99 Cluster: NAD/NADP octopine/nopaline dehydrogenas... 33 5.5
UniRef50_Q7JN85 Cluster: Twitchin; n=6; Bilateria|Rep: Twitchin ... 33 5.5
UniRef50_Q821V5 Cluster: UvrABC system protein C; n=9; Chlamydia... 33 5.5
UniRef50_UPI0001597301 Cluster: YfjR; n=1; Bacillus amyloliquefa... 33 7.3
UniRef50_Q1MPA3 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 33 7.3
UniRef50_Q1B326 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 33 7.3
UniRef50_Q13VQ8 Cluster: Putative dehydrogenase/oxidoreductase p... 33 7.3
UniRef50_A7DWL2 Cluster: Putative dehydrogenase; n=1; Streptomyc... 33 7.3
UniRef50_A3WMG5 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 33 7.3
UniRef50_Q0QZA7 Cluster: Gp121; n=1; Phage Syn9|Rep: Gp121 - Pha... 33 7.3
UniRef50_A6SMD9 Cluster: Predicted protein; n=1; Botryotinia fuc... 33 7.3
UniRef50_A1S4D3 Cluster: 23S rRNA (uracil-5-)-methyltransferase ... 33 7.3
UniRef50_Q8KL12 Cluster: Probable 6-phosphogluconate dehydrogena... 32 9.6
UniRef50_Q8EZ84 Cluster: K+ transport systems, NAD-binding compo... 32 9.6
UniRef50_Q31HA8 Cluster: GrpE chaparone protein; n=1; Thiomicros... 32 9.6
UniRef50_Q8IZN6 Cluster: ATP-binding cassette protein C4 splice ... 32 9.6
UniRef50_O67463 Cluster: tRNA (guanine-N(1)-)-methyltransferase;... 32 9.6
UniRef50_O15439 Cluster: Multidrug resistance-associated protein... 32 9.6
>UniRef50_P41572 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating; n=220; cellular organisms|Rep:
6-phosphogluconate dehydrogenase, decarboxylating -
Drosophila melanogaster (Fruit fly)
Length = 481
Score = 280 bits (687), Expect = 2e-74
Identities = 127/170 (74%), Positives = 153/170 (90%)
Frame = +3
Query: 111 EADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMV 290
+ADIALIGLAVMGQNLILNM++KG+VVCA+NRTV+KV+EFL NEAK TKVIGA SL+DMV
Sbjct: 4 QADIALIGLAVMGQNLILNMDEKGFVVCAYNRTVAKVKEFLANEAKDTKVIGADSLEDMV 63
Query: 291 SKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGIL 470
SKLK PRK++LLVKAG AVD+F+++L+PLLS GD+IIDGGNS+Y DT + C EL+ G+L
Sbjct: 64 SKLKSPRKVMLLVKAGSAVDDFIQQLVPLLSAGDVIIDGGNSEYQDTSRRCDELAKLGLL 123
Query: 471 YVGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAKANDEPCCDW 620
+VG GVSGGE+GAR+GPSLMPGGH AAWP I+ IFQAICAKA+ EPCC+W
Sbjct: 124 FVGSGVSGGEEGARHGPSLMPGGHEAAWPLIQPIFQAICAKADGEPCCEW 173
>UniRef50_P52209 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating; n=91; cellular organisms|Rep:
6-phosphogluconate dehydrogenase, decarboxylating - Homo
sapiens (Human)
Length = 483
Score = 278 bits (681), Expect = 9e-74
Identities = 128/171 (74%), Positives = 148/171 (86%), Gaps = 1/171 (0%)
Frame = +3
Query: 111 EADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMV 290
+ADIALIGLAVMGQNLILNMND G+VVCAFNRTVSKV++FL NEAKGTKV+GA SL +MV
Sbjct: 3 QADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKEMV 62
Query: 291 SKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGIL 470
SKLK+PR+I+LLVKAG AVD+F++KL+PLL GDIIIDGGNS+Y DT + C++L GIL
Sbjct: 63 SKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGIL 122
Query: 471 YVGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAK-ANDEPCCDW 620
+VG GVSGGE+GARYGPSLMPGG+ AWPHIK IFQ I AK EPCCDW
Sbjct: 123 FVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDW 173
>UniRef50_Q17761 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating; n=17; Fungi/Metazoa group|Rep:
6-phosphogluconate dehydrogenase, decarboxylating -
Caenorhabditis elegans
Length = 484
Score = 258 bits (633), Expect = 6e-68
Identities = 112/170 (65%), Positives = 143/170 (84%)
Frame = +3
Query: 111 EADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMV 290
EADIA+IGLAVMGQNLILNMND G+ VCAFNRTV V++FL NEAKGTK+IGA S+++M
Sbjct: 3 EADIAVIGLAVMGQNLILNMNDHGFTVCAFNRTVKLVDDFLANEAKGTKIIGAHSIEEMC 62
Query: 291 SKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGIL 470
KLKRPR++++L+KAG VD + ++P L +GDIIIDGGNS+Y D+ + ++L+ GI+
Sbjct: 63 KKLKRPRRVMMLIKAGTPVDMMIDAIVPHLEEGDIIIDGGNSEYTDSNRRSEQLAAKGIM 122
Query: 471 YVGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAKANDEPCCDW 620
+VG GVSGGE+GAR+GPSLMPGG+P AWPH+K+IFQ I AK+N EPCCDW
Sbjct: 123 FVGCGVSGGEEGARFGPSLMPGGNPKAWPHLKDIFQKIAAKSNGEPCCDW 172
>UniRef50_Q64V77 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating; n=10; cellular organisms|Rep:
6-phosphogluconate dehydrogenase, decarboxylating -
Bacteroides fragilis
Length = 491
Score = 184 bits (447), Expect = 2e-45
Identities = 91/178 (51%), Positives = 116/178 (65%), Gaps = 6/178 (3%)
Frame = +3
Query: 105 QNEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEE-----FLKNEAKGTKVIGA 269
QN+ DI LIGLAVMG+NL LNM +G+ V +NRTV VEE F+ AKG + G
Sbjct: 4 QNKTDIGLIGLAVMGENLALNMESRGWNVSVYNRTVPGVEEGVVERFINGRAKGKHIEGF 63
Query: 270 TSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKE 449
T ++ V + PRKI+++V+AG VDE +++L P LS GDI+IDGGNS Y DT + K
Sbjct: 64 TDIEAFVESIALPRKIMMMVRAGSPVDELMEQLFPYLSPGDILIDGGNSNYEDTNRRVKL 123
Query: 450 LSGTGILYVGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAKAND-EPCCDW 620
G L+VG GVSGGE+GA G S+MPGG AW +K I Q+I A+A D PCC W
Sbjct: 124 AESKGFLFVGAGVSGGEEGALNGASIMPGGSEKAWEEVKPILQSIAAQAPDGTPCCQW 181
>UniRef50_P80859 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating 2; n=27; cellular organisms|Rep:
6-phosphogluconate dehydrogenase, decarboxylating 2 -
Bacillus subtilis
Length = 469
Score = 182 bits (443), Expect = 6e-45
Identities = 88/168 (52%), Positives = 120/168 (71%)
Frame = +3
Query: 108 NEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDM 287
++ I +IGLAVMG+NL LN+ +G+ V +NR+ SK EEFL+ EAKG V+G S+++
Sbjct: 2 SKQQIGVIGLAVMGKNLALNIESRGFSVSVYNRSSSKTEEFLQ-EAKGKNVVGTYSIEEF 60
Query: 288 VSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGI 467
V L+ PRKI+L+VKAG A D ++ L+P L K DI+IDGGN+ Y DTQ+ KEL+ +GI
Sbjct: 61 VQSLETPRKILLMVKAGTATDATIQSLLPHLEKDDILIDGGNTYYKDTQRRNKELAESGI 120
Query: 468 LYVGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAKANDEPC 611
++G GVSGGE+GA GPS+MPGG A +K I +AI AK + EPC
Sbjct: 121 HFIGTGVSGGEEGALKGPSIMPGGQKEAHELVKPILEAISAKVDGEPC 168
>UniRef50_P21577 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating; n=65; cellular organisms|Rep:
6-phosphogluconate dehydrogenase, decarboxylating -
Synechococcus sp. (strain PCC 7942) (Anacystis nidulans
R2)
Length = 471
Score = 176 bits (429), Expect = 3e-43
Identities = 82/162 (50%), Positives = 117/162 (72%)
Frame = +3
Query: 126 LIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKLKR 305
LIGLAVMG+NL LN+ G+ + +NRT K E F+ + A+G ++ A SL+D V+ L+R
Sbjct: 8 LIGLAVMGENLALNIERNGFSLTVYNRTAEKTEAFMADRAQGKNIVPAYSLEDFVASLER 67
Query: 306 PRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMG 485
PR+I+++VKAG VD V++L PLL GD+IIDGGNS + DT++ K+L G+ ++GMG
Sbjct: 68 PRRILVMVKAGGPVDAVVEQLKPLLDPGDLIIDGGNSLFTDTERRVKDLEALGLGFMGMG 127
Query: 486 VSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAKANDEPC 611
VSGGE+GA GPSLMPGG AA+ ++ I ++I A+ +D PC
Sbjct: 128 VSGGEEGALNGPSLMPGGTQAAYEAVEPIVRSIAAQVDDGPC 169
>UniRef50_P52208 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating; n=25; Cyanobacteria|Rep:
6-phosphogluconate dehydrogenase, decarboxylating -
Synechocystis sp. (strain PCC 6803)
Length = 482
Score = 172 bits (419), Expect = 5e-42
Identities = 82/165 (49%), Positives = 115/165 (69%), Gaps = 2/165 (1%)
Frame = +3
Query: 126 LIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKLKR 305
+IGLAVMG+NL LN+ +G+ + FNR+ +K E+F+ A G + A ++++ V L+R
Sbjct: 15 VIGLAVMGENLALNVESRGFPIAVFNRSPNKTEKFMAERAVGKDIKAAYTVEEFVQLLER 74
Query: 306 PRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMG 485
PRKI+++VKAG VD + +L PLL +GD+IIDGGNS Y DT++ K+L TG+ +VGMG
Sbjct: 75 PRKILVMVKAGGPVDAVINELKPLLEEGDMIIDGGNSLYEDTERRTKDLEATGLGFVGMG 134
Query: 486 VSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAKAN--DEPCC 614
VSGGE+GA GPSLMPGG PAA+ ++ I I A+ D P C
Sbjct: 135 VSGGEEGALLGPSLMPGGTPAAYKELEPILTKIAAQVEDPDNPAC 179
>UniRef50_A5K3L2 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating; n=5; Plasmodium|Rep: 6-phosphogluconate
dehydrogenase, decarboxylating - Plasmodium vivax
Length = 473
Score = 160 bits (389), Expect = 2e-38
Identities = 80/166 (48%), Positives = 107/166 (64%), Gaps = 1/166 (0%)
Frame = +3
Query: 117 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVI-GATSLDDMVS 293
DI LIGLAVMGQNL LN+ G+ + +NRT + E+ LK +G I G +L+ +++
Sbjct: 6 DIGLIGLAVMGQNLSLNIASNGFTIGVYNRTYERTEDTLKKAKEGNLPIQGYETLEQLIN 65
Query: 294 KLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILY 473
LK+PRKI+LL+KAG AVDE +K ++ +GDIIIDGGN YL+T++ + Y
Sbjct: 66 NLKKPRKIILLIKAGPAVDETIKNILKHFEEGDIIIDGGNEWYLNTERRITLCEEHKVEY 125
Query: 474 VGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAKANDEPC 611
+ MGVSGGE GARYG S MPGG A+ IK+I + AK PC
Sbjct: 126 LAMGVSGGEAGARYGCSFMPGGSKYAYDTIKDILEKCSAKVGTSPC 171
>UniRef50_Q5HP42 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating; n=17; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, decarboxylating - Staphylococcus
epidermidis (strain ATCC 35984 / RP62A)
Length = 468
Score = 158 bits (384), Expect = 9e-38
Identities = 79/165 (47%), Positives = 109/165 (66%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
I ++GLAVMG+NL N+ +GY V +NR+ K +E +K E+ G ++ SL++ V L
Sbjct: 5 IGVVGLAVMGKNLAWNIESRGYSVSVYNRSRQKTDEMVK-ESPGREIYPTYSLEEFVESL 63
Query: 300 KRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVG 479
++PRKI+L+VKAG A D + L+PLL DI+IDGGN+ Y DT + K L+ + I ++G
Sbjct: 64 EKPRKILLMVKAGPATDATIDGLLPLLDDDDILIDGGNTNYQDTIRRNKALAESSINFIG 123
Query: 480 MGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAKANDEPCC 614
MGVSGGE GA GPSLMPGG A+ + +I AI AKA D C
Sbjct: 124 MGVSGGEIGALTGPSLMPGGQKDAYNKVSDILDAIAAKAQDGASC 168
>UniRef50_Q836Q9 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating; n=11; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, decarboxylating - Enterococcus faecalis
(Streptococcus faecalis)
Length = 473
Score = 155 bits (376), Expect = 8e-37
Identities = 78/164 (47%), Positives = 114/164 (69%), Gaps = 2/164 (1%)
Frame = +3
Query: 126 LIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGAT-SLDDMVSKLK 302
++G+AVMG+NL LN+ +GY V +NRT SK E + E K AT S+++ V+ ++
Sbjct: 8 VVGMAVMGKNLALNIESRGYTVALYNRTGSKTTEVV--EEHPDKNFQATYSIEEFVNAIE 65
Query: 303 RPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGM 482
+PR+I+L+VKAG A D +++L+P L KGDI+IDGGN+ + DT + +EL+ +GI ++G
Sbjct: 66 KPRRIMLMVKAGPATDATIQELLPHLDKGDILIDGGNTFFKDTMRRNEELANSGINFIGT 125
Query: 483 GVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAKAND-EPC 611
GVSGGE+GA GPS+MPGG A+ + I + I AKA D EPC
Sbjct: 126 GVSGGEEGALKGPSIMPGGQKEAYELVAPILEKISAKAEDGEPC 169
>UniRef50_Q1DDR1 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating; n=2; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, decarboxylating - Myxococcus xanthus
(strain DK 1622)
Length = 474
Score = 154 bits (374), Expect = 1e-36
Identities = 70/166 (42%), Positives = 114/166 (68%)
Frame = +3
Query: 114 ADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVS 293
A + G+ VMG +L LN+ D G+ V ++R +++E + +V G SL+ V
Sbjct: 7 AQFGVAGMGVMGASLALNIADHGFRVAVWDRHAERIDEMHRKHGH-PEVWGTESLEAFVQ 65
Query: 294 KLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILY 473
+L+RPRK++L+V AG AVD +++L+PL+++GD+I+D GNS +LDT++ ++ GI +
Sbjct: 66 RLERPRKVLLMVTAGAAVDSMLERLLPLMAEGDVIMDAGNSWFLDTRRREEQCKAKGIHF 125
Query: 474 VGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAKANDEPC 611
+G+GVSGGE+GAR GPS+MPGG P+A+ ++ +F+AI A + PC
Sbjct: 126 LGVGVSGGEEGARNGPSIMPGGAPSAYELVRPVFEAIAANTDMGPC 171
>UniRef50_Q92P61 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating; n=25; Alphaproteobacteria|Rep:
6-phosphogluconate dehydrogenase, decarboxylating -
Rhizobium meliloti (Sinorhizobium meliloti)
Length = 476
Score = 153 bits (372), Expect = 2e-36
Identities = 69/172 (40%), Positives = 114/172 (66%), Gaps = 1/172 (0%)
Frame = +3
Query: 108 NEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNE-AKGTKVIGATSLDD 284
++A+I LIGL VMG NL LN+ +KG + FNRTV +F A +++ ++++
Sbjct: 2 SQAEIGLIGLGVMGSNLALNIAEKGNRIAVFNRTVDATRKFYAEAGALKDQIVPCETIEE 61
Query: 285 MVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTG 464
V+ ++ PR I++++KAG VD+ ++ L P L+KGDI+ID GN+ + DT + L +G
Sbjct: 62 FVAAIRPPRPIIIMIKAGDPVDQQMEALKPHLAKGDIMIDAGNANFRDTMRRFDALKDSG 121
Query: 465 ILYVGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAKANDEPCCDW 620
+ ++GMGVSGGE+GAR+GPS+M GG ++ ++++ +I AK + +PC W
Sbjct: 122 LTFIGMGVSGGEEGARHGPSIMVGGTEESYRRVEKVLTSIAAKYDSDPCVAW 173
>UniRef50_P37754 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating; n=292; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, decarboxylating - Escherichia coli
Length = 468
Score = 153 bits (372), Expect = 2e-36
Identities = 77/169 (45%), Positives = 108/169 (63%), Gaps = 1/169 (0%)
Frame = +3
Query: 108 NEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDM 287
++ I ++G+AVMG+NL LN+ +GY V FNR+ K EE + E G K++ ++ +
Sbjct: 2 SKQQIGVVGMAVMGRNLALNIESRGYTVSVFNRSREKTEEVIA-ENPGKKLVPYYTVQEF 60
Query: 288 VSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGI 467
V L+ PR+I+L+VKAG D + L P L KGDIIIDGGN+ + DT + +ELS G
Sbjct: 61 VESLETPRRILLMVKAGSGTDSAIDSLKPYLDKGDIIIDGGNTFFQDTIRRNRELSAEGF 120
Query: 468 LYVGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAKAND-EPC 611
++G GVSGGE+GA GPS+MPGG A+ + I + I A A D EPC
Sbjct: 121 NFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILKQIAAVAEDGEPC 169
>UniRef50_P31072 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating; n=43; Trypanosomatidae|Rep:
6-phosphogluconate dehydrogenase, decarboxylating -
Trypanosoma brucei brucei
Length = 479
Score = 150 bits (363), Expect = 3e-35
Identities = 72/169 (42%), Positives = 106/169 (62%), Gaps = 4/169 (2%)
Frame = +3
Query: 117 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDM--- 287
D+ ++GL VMG NL LN+ +KG+ V FNRT SK EEF+K A + + M
Sbjct: 4 DVGVVGLGVMGANLALNIAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETMEAF 63
Query: 288 VSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGI 467
+ LK+PRK ++LV+AG A D ++L + KGDI++D GN+ + D + ++L G+
Sbjct: 64 AASLKKPRKALILVQAGAATDSTTEQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEAAGL 123
Query: 468 LYVGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAKAND-EPC 611
++GMG+SGGE+GAR GP+ PGG + W I+ I +A AKA+D PC
Sbjct: 124 RFLGMGISGGEEGARKGPAFFPGGTLSVWEEIRPIVEAAAAKADDGRPC 172
>UniRef50_Q3J9H5 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating; n=2; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, decarboxylating - Nitrosococcus oceani
(strain ATCC 19707 / NCIMB 11848)
Length = 481
Score = 147 bits (357), Expect = 2e-34
Identities = 73/173 (42%), Positives = 106/173 (61%), Gaps = 4/173 (2%)
Frame = +3
Query: 114 ADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSK----VEEFLKNEAKGTKVIGATSLD 281
ADI +IGL VMG NL LN+ ++G+ V ++R K + K A+ + +
Sbjct: 10 ADIGIIGLGVMGANLGLNIAEQGFNVAGYDRNPEKGARLTQMAQKQLAEDAPMEAYHDIQ 69
Query: 282 DMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGT 461
++ L++PR I+LLV AG VD ++ L P L +G I+IDGGNS + DT + + L+
Sbjct: 70 PFIASLRQPRLILLLVPAGDPVDGVIQDLSPDLEQGTILIDGGNSHFRDTDRRIQTLAQQ 129
Query: 462 GILYVGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAKANDEPCCDW 620
+ +VGMGVSGGE GAR+GPS+MPGG AW ++ + +A AK +EPC DW
Sbjct: 130 NVHFVGMGVSGGEAGARHGPSMMPGGDSTAWERLRPMLEAAAAKVGEEPCVDW 182
>UniRef50_Q660W3 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating; n=3; Borrelia burgdorferi group|Rep:
6-phosphogluconate dehydrogenase, decarboxylating -
Borrelia garinii
Length = 464
Score = 146 bits (355), Expect = 3e-34
Identities = 74/166 (44%), Positives = 106/166 (63%)
Frame = +3
Query: 117 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSK 296
D+ + GL VMG NL LN+ D G+ V +NR K E F+K + K+ G ++ V
Sbjct: 2 DVGIYGLGVMGGNLALNIADNGFNVSVYNRDSEKTEIFVKQNSH-KKINGFKDVESFVKS 60
Query: 297 LKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYV 476
LK PRKI+L+V + AV++ V++++PLL+K DIIIDGGNS Y +T + KEL I +V
Sbjct: 61 LKPPRKIILMVTS-LAVEKVVEQILPLLNKSDIIIDGGNSHYKNTMRIEKELFAKDIYFV 119
Query: 477 GMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAKANDEPCC 614
G+G+SGGE GAR+GP+LM GG +A+ ++ I I AK + C
Sbjct: 120 GLGISGGERGARFGPALMYGGSKSAYEILEPILNKIAAKTKNNDVC 165
>UniRef50_Q5FHQ8 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating; n=5; Lactobacillus|Rep:
6-phosphogluconate dehydrogenase, decarboxylating -
Lactobacillus acidophilus
Length = 467
Score = 146 bits (355), Expect = 3e-34
Identities = 74/166 (44%), Positives = 109/166 (65%), Gaps = 1/166 (0%)
Frame = +3
Query: 126 LIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKLKR 305
+IGL+VMG+NL LN+ + G+ V ++ +V+ K E K+ +L++ V+ L++
Sbjct: 6 VIGLSVMGKNLALNVRNHGFSVSGYSIDKPEVDALAKYE--DDKLKPCYTLEEFVNSLEK 63
Query: 306 PRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMG 485
PRKI++ + AG VD+ + KL+PLL KGDI+IDGGNS Y DT + E+ GI ++GMG
Sbjct: 64 PRKILIQIMAGDPVDQTLHKLLPLLDKGDIVIDGGNSNYHDTNRRYHEMEKHGIHFIGMG 123
Query: 486 VSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAKAND-EPCCDW 620
VSGGE+GA GP+LMPGG A+ + I +AI AK D +PC +
Sbjct: 124 VSGGEEGALNGPALMPGGDEEAYKEVAPILEAIAAKNKDGKPCVSY 169
>UniRef50_A7BAU3 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 488
Score = 146 bits (355), Expect = 3e-34
Identities = 68/169 (40%), Positives = 106/169 (62%)
Frame = +3
Query: 114 ADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVS 293
ADI + GL VMG NL N+ GY FNRT ++ E+ + + A++L+D V+
Sbjct: 11 ADIGVYGLGVMGANLARNLARNGYATAVFNRTPARTEKLMAEHGDEATFVPASTLEDFVA 70
Query: 294 KLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILY 473
L+ PR +++V+AG + D +++L L+ +GDII+D GNS + DT + K + G+ +
Sbjct: 71 SLRAPRVAIMMVQAGPSTDAVMEQLADLMDEGDIIVDCGNSLFTDTIRREKWAAERGLHF 130
Query: 474 VGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAKANDEPCCDW 620
VG GVSGGE+GA +GPS+MPGG PA++ + +F+AI + PCC +
Sbjct: 131 VGAGVSGGEEGALWGPSIMPGGTPASYDRLGPMFEAIAGTYDGVPCCTY 179
>UniRef50_Q68Y99 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating; n=1; Cyanidioschyzon merolae|Rep:
6-phosphogluconate dehydrogenase, decarboxylating -
Cyanidioschyzon merolae (Red alga)
Length = 640
Score = 146 bits (355), Expect = 3e-34
Identities = 77/176 (43%), Positives = 105/176 (59%), Gaps = 10/176 (5%)
Frame = +3
Query: 114 ADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAK---------GTKVIG 266
+D +IGLAVMGQN LN+ G+ V +NRT ++ E ++ + V G
Sbjct: 100 SDAGVIGLAVMGQNFALNLASHGWRVSVYNRTYARTAETVERAQRELAADDTTASGSVTG 159
Query: 267 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 446
L V LKRPR++ LLVKAG AVD V+ L +L GDII+DGGN Y +T++
Sbjct: 160 FADLRSFVLSLKRPRRVFLLVKAGSAVDATVEALAEVLEPGDIIVDGGNEWYENTERRAA 219
Query: 447 ELSGTGILYVGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAKA-NDEPC 611
++ G+LYVGMGVSGGE+GARYGPSLMPGG A+ + + + + A+ PC
Sbjct: 220 SVAARGLLYVGMGVSGGEEGARYGPSLMPGGSREAYQQLAPLLEQVAAQVPGSGPC 275
>UniRef50_A2GAV3 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating; n=3; Trichomonas vaginalis|Rep:
6-phosphogluconate dehydrogenase, decarboxylating -
Trichomonas vaginalis G3
Length = 489
Score = 143 bits (347), Expect = 3e-33
Identities = 74/170 (43%), Positives = 107/170 (62%), Gaps = 2/170 (1%)
Frame = +3
Query: 117 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLK-NEAKGTKVIGATSLDDMVS 293
D+ + GL MG N+ N G+ V AFNRT ++ E LK NE + G +++++V
Sbjct: 4 DLCVFGLGTMGSNIARNFAHHGFKVAAFNRTWARTEALLKLNEPN---ITGYKTIEEVVE 60
Query: 294 KLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILY 473
LK+PR +++V A F VD +++L LL K D+IIDGGNS + DT++ K + TG+ +
Sbjct: 61 ALKKPRIFLIIVTAEF-VDNVIEQLKVLLEKDDVIIDGGNSHWPDTERRQKAIEPTGVHF 119
Query: 474 VGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAKA-NDEPCCDW 620
VGMG+SGGE+GA GPS+M GGH W + K + I AKA +D PC D+
Sbjct: 120 VGMGISGGEEGALNGPSMMFGGHSQDWDNCKRVLLPIAAKAPDDTPCVDY 169
>UniRef50_A6ELE2 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating; n=1; unidentified eubacterium
SCB49|Rep: 6-phosphogluconate dehydrogenase,
decarboxylating - unidentified eubacterium SCB49
Length = 628
Score = 141 bits (341), Expect = 1e-32
Identities = 75/175 (42%), Positives = 110/175 (62%), Gaps = 6/175 (3%)
Frame = +3
Query: 114 ADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEE--FLKNEAKGTKVIGATSLDDM 287
+D L GL VMG++L N+ + G+ + FNR V VEE + +A+ +++ A + DD+
Sbjct: 166 SDFGLFGLGVMGKSLCRNLANNGFKISMFNRHVDGVEEQVAVNFKAQFSELSTAAAFDDI 225
Query: 288 ---VSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSG 458
V+ L++PRKI+L+V AG +D ++ L+P LSK DI+IDGGNS YL T++ L
Sbjct: 226 SAFVNSLQQPRKIMLMVNAGKTIDFVIEDLLPHLSKNDILIDGGNSNYLKTKERFDYLKD 285
Query: 459 TGILYVGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAK-ANDEPCCDW 620
GI ++G GVSGGE+GA GPS+MP G A+ +K + I AK N PCC +
Sbjct: 286 KGIHFIGTGVSGGEEGALKGPSIMPSGAAEAYEDVKPFLETIAAKDQNGLPCCTY 340
>UniRef50_Q8CX65 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating; n=2; Bacillaceae|Rep:
6-phosphogluconate dehydrogenase, decarboxylating -
Oceanobacillus iheyensis
Length = 465
Score = 133 bits (322), Expect = 3e-30
Identities = 65/167 (38%), Positives = 97/167 (58%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
I + GL VMG NL +NM +KG V +N T E+F K+ L+ V+ L
Sbjct: 4 IGVFGLGVMGANLAMNMANKGEKVAVYNYTSDLTEKF-KSNFTSDNAEAHYDLERFVNSL 62
Query: 300 KRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVG 479
++PRK+ L+V AG +D + L+PLL K DI++DGGNS + D+ + L GI +V
Sbjct: 63 EKPRKVFLMVTAGPVIDSVIDSLVPLLDKDDIMMDGGNSNFNDSNRRYHRLKEAGIHFVS 122
Query: 480 MGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAKANDEPCCDW 620
+GVSGGE+GA +GP+LMP G + + I + I A+ + + CC +
Sbjct: 123 VGVSGGEEGALHGPALMPSGDEKVYQEVAPILEKIAAQVDGKACCGY 169
>UniRef50_Q7TZG1 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating; n=21; Actinobacteria (class)|Rep:
6-phosphogluconate dehydrogenase, decarboxylating -
Mycobacterium bovis
Length = 685
Score = 132 bits (319), Expect = 6e-30
Identities = 59/157 (37%), Positives = 95/157 (60%)
Frame = +3
Query: 144 MGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKLKRPRKIVL 323
MG N+ N GY V NR+V+K + LK + K + + ++ + ++ L++PR++++
Sbjct: 1 MGSNIARNFARHGYTVAVHNRSVAKTDALLKEHSSDGKFVRSETIPEFLAALEKPRRVLI 60
Query: 324 LVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSGGED 503
+VKAG A D + +L + GDIIIDGGN+ Y DT + K + G+ +VG G+SGGE+
Sbjct: 61 MVKAGEATDAVINELADAMEPGDIIIDGGNALYTDTMRREKAMRERGLHFVGAGISGGEE 120
Query: 504 GARYGPSLMPGGHPAAWPHIKEIFQAICAKANDEPCC 614
GA GPS+MPGG ++ + + + I A + PCC
Sbjct: 121 GALNGPSIMPGGPAESYQSLGPLLEEISAHVDGVPCC 157
>UniRef50_O32911 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating; n=30; cellular organisms|Rep:
6-phosphogluconate dehydrogenase, decarboxylating -
Mycobacterium leprae
Length = 486
Score = 131 bits (316), Expect = 1e-29
Identities = 61/167 (36%), Positives = 97/167 (58%)
Frame = +3
Query: 114 ADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVS 293
A I + GLAVMG N+ N GY V NR+++K + LK + ++ + ++
Sbjct: 14 AQIGVTGLAVMGSNIARNFARHGYTVALHNRSIAKTDTLLKEHGSEGNFVRTETIPEFLA 73
Query: 294 KLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILY 473
L+ PR+++++VKAG A D + +L ++ DIIIDGGNS + DT + K + G+ +
Sbjct: 74 ALQTPRRVLIMVKAGDATDAVINELADVMEPSDIIIDGGNSLFTDTIRREKAMRERGLHF 133
Query: 474 VGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAKANDEPCC 614
VG G+SGGE+GA GPS+MPGG ++ + + + I A + CC
Sbjct: 134 VGAGISGGEEGALNGPSIMPGGPAESYTSLGPLLEEISAHVDGVSCC 180
>UniRef50_Q5IWZ8 Cluster: Plastid 6-phosphogluconate
2-dehydrogenase; n=1; Prototheca wickerhamii|Rep:
Plastid 6-phosphogluconate 2-dehydrogenase - Prototheca
wickerhamii
Length = 507
Score = 130 bits (314), Expect = 3e-29
Identities = 65/158 (41%), Positives = 98/158 (62%), Gaps = 4/158 (2%)
Frame = +3
Query: 150 QNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAK---GTKVIGATSLDDMVSKLKRPRKIV 320
QNL LN+ +KG+ + +NR+ K + + K G ++ G D V LKRPR+I+
Sbjct: 168 QNLALNVAEKGFHISVYNRSGEKTDAAVSRAVKEGVGERLHGVQGAKDFVLSLKRPRRII 227
Query: 321 LLVKAGFAVDEFVKKLIP-LLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSGG 497
+LVKAG VD K+L ++ DIIIDGGN Y +T++ EL+ G ++GMGVSGG
Sbjct: 228 ILVKAGAPVDSTSKQLTEFVVEPRDIIIDGGNEWYENTERRQAELATKGSHHIGMGVSGG 287
Query: 498 EDGARYGPSLMPGGHPAAWPHIKEIFQAICAKANDEPC 611
E+GAR GP++MPGG A+ H++ + + + A+ +D C
Sbjct: 288 EEGARNGPAMMPGGDKGAYSHLRPVVEKVAAQTDDGAC 325
>UniRef50_Q11V91 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating; n=2; Bacteroidetes|Rep:
6-phosphogluconate dehydrogenase, decarboxylating -
Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Length = 627
Score = 129 bits (312), Expect = 5e-29
Identities = 68/171 (39%), Positives = 104/171 (60%), Gaps = 6/171 (3%)
Frame = +3
Query: 126 LIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNE--AKGTKVIGATSLDDM---V 290
L+GL VMG++L N G + +NR V EE + + A+ ++ A +D+
Sbjct: 170 LVGLGVMGKSLARNFAANGVALSLYNRFVKGSEEQVAEKCIAEYPELQSAKGFEDLKTFA 229
Query: 291 SKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGIL 470
+ L++PRKI L++KAG D F+++L+P L+ GD++IDGGNS Y DT++ + L+ GI
Sbjct: 230 ASLEQPRKIFLMIKAGEETDTFIEELVPYLNAGDVLIDGGNSYYGDTKRRIEFLARKGIY 289
Query: 471 YVGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAK-ANDEPCCDW 620
++G GVSGGE GA GPS+MP G P A+ +++ I AK E CC +
Sbjct: 290 FIGTGVSGGEQGALKGPSIMPSGDPDAYALVEKYLTLIAAKDKQGESCCTY 340
>UniRef50_A6W129 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating; n=8; Gammaproteobacteria|Rep:
6-phosphogluconate dehydrogenase, decarboxylating -
Marinomonas sp. MWYL1
Length = 507
Score = 126 bits (303), Expect = 6e-28
Identities = 70/177 (39%), Positives = 105/177 (59%), Gaps = 8/177 (4%)
Frame = +3
Query: 96 KMPQNEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNE-------AKGT 254
K QN +I +GL VMG+NL LN+ D GY V F+ K+++ L E +
Sbjct: 3 KTNQN-CNIGFVGLGVMGKNLALNLADHGYRVAGFDLDAHKIQDVLDTEKAERPDPSAEA 61
Query: 255 KVIGATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPL-LSKGDIIIDGGNSQYLDT 431
++IG ++++DM++ L +PR IV+LV AG VD LI L DI++D GNSQ+ DT
Sbjct: 62 RIIGCSNMEDMLANLVKPRVIVVLVPAGSPVDAVCNSLIDAGLEADDIVVDCGNSQWTDT 121
Query: 432 QKWCKELSGTGILYVGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAKAND 602
+ E + G VSGGE GAR+GPSLMPGG +W +++ +++A+ AK ++
Sbjct: 122 IRREAEYKEK-FKFFGTAVSGGEVGARFGPSLMPGGDADSWKYLQPMWEAVAAKVDE 177
>UniRef50_Q8SRX1 Cluster: 6-PHOSPHOGLUCONATE DEHYDROGENASE; n=1;
Encephalitozoon cuniculi|Rep: 6-PHOSPHOGLUCONATE
DEHYDROGENASE - Encephalitozoon cuniculi
Length = 458
Score = 122 bits (293), Expect = 9e-27
Identities = 70/178 (39%), Positives = 105/178 (58%), Gaps = 4/178 (2%)
Frame = +3
Query: 99 MPQN-EADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATS 275
MPQ + +I LIGL VMG +L LN+ +GY + FNRT SK ++ ++ + S
Sbjct: 1 MPQTPKMEIGLIGLGVMGHSLALNIVSRGYRLHVFNRTSSKTDDLVRERRD---ICPHYS 57
Query: 276 LDDMVSKLKR-PRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 452
++D+V +K PR I+L++ +G VD F+++L L K D++IDGGNS Y DT + +
Sbjct: 58 VEDLVVGIKTSPRVILLMLTSGKVVDVFLEELSRYLGKDDVVIDGGNSSYKDTIRRNRYK 117
Query: 453 SGTGILYVGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICA--KANDEPCCDW 620
G +VG G+SGGE+GARYGPS+M G +W ++ I A + + CC W
Sbjct: 118 FG----FVGCGISGGEEGARYGPSIMVGCDKDSWEKVQGFLTDISAVEVSGSKRCCVW 171
>UniRef50_A5JEL6 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating; n=1; Nosema bombycis|Rep:
6-phosphogluconate dehydrogenase, decarboxylating -
Nosema bombycis
Length = 457
Score = 117 bits (281), Expect = 3e-25
Identities = 67/171 (39%), Positives = 100/171 (58%), Gaps = 3/171 (1%)
Frame = +3
Query: 117 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSK 296
+I LIG+ MG+ L LN+NDKGY + +NRT SK E +K +I +++D+V
Sbjct: 2 EIGLIGIGNMGRELALNINDKGYKLHVYNRTTSKTENLVKIR---DSIIPHYTVEDLVKC 58
Query: 297 LKR-PRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILY 473
L P+ I++L+ G A+D +K+L L++ DI+ID GNS Y DT + E +
Sbjct: 59 LPNDPKIIMVLLTTGDAIDLMLKELSNFLNETDIVIDLGNSYYKDTIRRNNEFK---FQF 115
Query: 474 VGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIF--QAICAKANDEPCCDW 620
VG G+SGGE GARYG S+M G W I++I ++ +K ++ CC W
Sbjct: 116 VGAGISGGEFGARYGASIMVGCATDVWSKIEKILFDLSVTSKFTNKKCCGW 166
>UniRef50_UPI000050FFB4 Cluster: COG0362: 6-phosphogluconate
dehydrogenase; n=1; Brevibacterium linens BL2|Rep:
COG0362: 6-phosphogluconate dehydrogenase -
Brevibacterium linens BL2
Length = 511
Score = 114 bits (275), Expect = 1e-24
Identities = 63/166 (37%), Positives = 94/166 (56%), Gaps = 5/166 (3%)
Frame = +3
Query: 114 ADIALIGLAVMGQNLILNMNDK-----GYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSL 278
A++ +IG VMG NL N+ G V ++R V + + L E + + A+S
Sbjct: 3 AEVGVIGTGVMGSNLARNLARNLAARSGARVAVYDRDVDRAQA-LAVEHPDAEFLVASSP 61
Query: 279 DDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSG 458
D+ SKL PR +L+V AG A D + L+ + GD+I+DGGNS + DT + +
Sbjct: 62 ADLASKLSGPRVAILMVNAGAATDSAINDLVEVFEPGDVIVDGGNSLFTDTIARGETVRQ 121
Query: 459 TGILYVGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAKA 596
GI +VG+G+SGGE GA GPS+M GG +AW ++ I + I A+A
Sbjct: 122 AGIEFVGVGISGGEVGALEGPSMMVGGTESAWSRLRPILEPIAARA 167
>UniRef50_A6PJ87 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating; n=3; Gammaproteobacteria|Rep:
6-phosphogluconate dehydrogenase, decarboxylating -
Shewanella sediminis HAW-EB3
Length = 517
Score = 112 bits (270), Expect = 6e-24
Identities = 69/174 (39%), Positives = 97/174 (55%), Gaps = 11/174 (6%)
Frame = +3
Query: 117 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGT----------KVIG 266
D+ +IGL VMG+NL LN+ D Y V AF+ K+E ++ E +V G
Sbjct: 9 DVGVIGLGVMGKNLSLNIADNRYRVAAFDLDTDKIEGLVQQERTERDRSQQIDFELRVNG 68
Query: 267 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPL-LSKGDIIIDGGNSQYLDTQKWC 443
++L +M+S L++PR ++L V AG VD LI + DI+ID GNS + DT +
Sbjct: 69 CSNLSEMLSILEKPRVLILSVPAGSPVDGVCNALIEAGIDHDDIVIDTGNSLWTDTVER- 127
Query: 444 KELSGTGILYVGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAKANDE 605
+ + + VSGGE GAR+GPSLMP G AW IK I++AI AK + E
Sbjct: 128 EARYASQFTFFSCAVSGGEMGARFGPSLMPSGDIKAWGRIKPIWEAIAAKVDPE 181
>UniRef50_A0Y665 Cluster: 6-phosphogluconate dehydrogenase; n=3;
Alteromonadales|Rep: 6-phosphogluconate dehydrogenase -
Alteromonadales bacterium TW-7
Length = 457
Score = 110 bits (264), Expect = 3e-23
Identities = 64/170 (37%), Positives = 95/170 (55%), Gaps = 6/170 (3%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFL---KNEAKGTKVIGATSLDDMV 290
+AL+GL VMG+NL LN+ DKG + A+++ EE + K++ K+ + L DMV
Sbjct: 3 VALVGLGVMGKNLALNLIDKGITLVAYDKNPHAGEELISCAKSQGMADKLHIVSDLGDMV 62
Query: 291 SKLKRPRKIVLLVKAGFAVDEFVKKLIPL-LSKGDIIIDGGNSQYLD--TQKWCKELSGT 461
+L+ PR I+LLV AG VD +L+ + DII+D GNS Y D T+K +
Sbjct: 63 RRLEAPRSILLLVPAGELVDTVCNELVNAGVECDDIIVDCGNSNYKDGITRKLKYQ---N 119
Query: 462 GILYVGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAKANDEPC 611
+ MG+SGG +GAR+GP++M G W I+ F+ + A N C
Sbjct: 120 KFEFATMGISGGAEGARHGPAMMASGSEGGWERIEPWFEKVAASYNGSSC 169
>UniRef50_Q9K9H3 Cluster: 6-phosphogluconate dehydrogenase; n=7;
Firmicutes|Rep: 6-phosphogluconate dehydrogenase -
Bacillus halodurans
Length = 298
Score = 105 bits (252), Expect = 9e-22
Identities = 61/141 (43%), Positives = 83/141 (58%)
Frame = +3
Query: 117 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSK 296
+I LIGL MG NL LN+ D + + A++ V+E AK A SL+++VSK
Sbjct: 2 EIGLIGLGRMGYNLGLNILDHEHQLVAYDVNREAVKEIGLAGAKE-----ADSLEELVSK 56
Query: 297 LKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYV 476
L PRKI ++V AG + V +L LL +GD++IDGGN+ Y DT + K+ G+ +V
Sbjct: 57 LSAPRKIWVMVPAGDITENVVSQLSSLLDEGDVVIDGGNANYKDTLRRAKQYEAKGLHFV 116
Query: 477 GMGVSGGEDGARYGPSLMPGG 539
G SGG DGAR G LM GG
Sbjct: 117 DAGTSGGIDGAREGACLMVGG 137
>UniRef50_Q7QWR3 Cluster: GLP_26_8052_6637; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_26_8052_6637 - Giardia lamblia ATCC
50803
Length = 471
Score = 103 bits (247), Expect = 3e-21
Identities = 59/160 (36%), Positives = 93/160 (58%), Gaps = 2/160 (1%)
Frame = +3
Query: 117 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSK 296
DI ++GL MG+NL LN + + V +NRT SK + + +E K + S+ D V+
Sbjct: 2 DIGIVGLGAMGKNLALNFHRNKFKVAIYNRTHSKAKA-VADELKSESLKAYESVSDFVAS 60
Query: 297 LKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQY-LDTQKWCKELSGTGILY 473
L +PR IVLLV+A AVD + + + + DIIID GNS Y L ++ + + +
Sbjct: 61 LVKPRVIVLLVQAD-AVDSVGEMMAKCMQEDDIIIDSGNSYYKLTEERKVRFHKNFKVHF 119
Query: 474 VGMGVSGGEDGARYGPSLMPGG-HPAAWPHIKEIFQAICA 590
G+G+SGGE+GA +GP++M GG +A + + + +CA
Sbjct: 120 YGIGISGGEEGALWGPAIMVGGDEESARKRLLPLLEKVCA 159
>UniRef50_Q4UGE1 Cluster: 6-phosphogluconate dehydrogenase,
putative; n=2; Theileria|Rep: 6-phosphogluconate
dehydrogenase, putative - Theileria annulata
Length = 443
Score = 100 bits (239), Expect = 3e-20
Identities = 61/167 (36%), Positives = 92/167 (55%), Gaps = 13/167 (7%)
Frame = +3
Query: 111 EADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEF---LKNEAKG---------- 251
E++ ++GL VM N+ +G+ V + R+ ++E F LK + K
Sbjct: 6 ESEFGIVGLGVMASAYATNLYFRGFKVSVWTRSQKEIEIFNEKLKEQPKFNGLDADSVDL 65
Query: 252 TKVIGATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDT 431
T+V +L++ V L RPR I++L+ AG AVD + KLIPLL + D+++DGGN Y +T
Sbjct: 66 TRVKCYMNLEEFVLSLNRPRMILILIIAGEAVDCVLDKLIPLLDRDDLVVDGGNEWYNNT 125
Query: 432 QKWCKELSGTGILYVGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEI 572
++ GI Y GMG+SGGE GA P LM GG+ + +K I
Sbjct: 126 ERRILRCKEEGIRYSGMGISGGERGALTHPCLMFGGNFEDYNKLKRI 172
>UniRef50_A7AQE8 Cluster: 6-phosphogluconate dehydrogenase,
putative; n=1; Babesia bovis|Rep: 6-phosphogluconate
dehydrogenase, putative - Babesia bovis
Length = 453
Score = 97.9 bits (233), Expect = 2e-19
Identities = 52/155 (33%), Positives = 85/155 (54%)
Frame = +3
Query: 114 ADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVS 293
++ +IGL VMG N+ +G V AF+ S++++ ++ T+ + +
Sbjct: 3 SEFGVIGLGVMGGAYTQNLTSRGIRVSAFSIQQSEIDKMESLRIPNLQLF--TNFGEYIE 60
Query: 294 KLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILY 473
L++PRKI++LV AG AVD+ + ++ LL GDI+IDGGN Y +T + G+ +
Sbjct: 61 SLEKPRKILMLVTAGKAVDQVLNCILGLLEVGDIVIDGGNEWYENTIGRIERCKQKGVHF 120
Query: 474 VGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQ 578
MGVSGGE GAR P +M G + +K+ +
Sbjct: 121 CAMGVSGGERGARISPCIMFSGERTVYDMVKQYIE 155
>UniRef50_P54448 Cluster: Uncharacterized protein yqeC; n=13;
Bacteria|Rep: Uncharacterized protein yqeC - Bacillus
subtilis
Length = 297
Score = 95.9 bits (228), Expect = 7e-19
Identities = 55/153 (35%), Positives = 86/153 (56%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
I LIGL MG N+ D+ + V ++ + V+E A+GT T+L + +S L
Sbjct: 3 IGLIGLGKMGINIGKQFIDRNHQVVGYDVNQAAVDELKAYGAEGT-----TNLKEFISLL 57
Query: 300 KRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVG 479
PR + ++V G VD ++ + PLLSKGD+II+ GNS Y ++ + ++ GI Y+
Sbjct: 58 HPPRILWVMVPHGI-VDAVLRDVSPLLSKGDMIIEAGNSHYKESIRRYNQMKEAGIHYLD 116
Query: 480 MGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQ 578
G SGG +GAR+G M GG AW ++ +F+
Sbjct: 117 AGTSGGMEGARHGACFMVGGDHEAWEIVEPLFR 149
>UniRef50_Q9CDN4 Cluster: 6-phosphogluconate dehydrogenase; n=12;
Firmicutes|Rep: 6-phosphogluconate dehydrogenase -
Lactococcus lactis subsp. lactis (Streptococcus lactis)
Length = 302
Score = 91.1 bits (216), Expect = 2e-17
Identities = 54/154 (35%), Positives = 85/154 (55%), Gaps = 1/154 (0%)
Frame = +3
Query: 126 LIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKLKR 305
+IGL MG NL+ N D V A++ VEE + K+ +++++++++L
Sbjct: 6 MIGLGKMGMNLVKNAVDHEIEVVAYDLNTKAVEEA---KDYSDKITAVSTIENLLTELPA 62
Query: 306 PRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMG 485
+ + L++ AG + ++ L LS GDI+IDGGNS Y D + K L+ GI + +G
Sbjct: 63 SKIVWLMLPAGTPTNSTIEMLSEKLSAGDILIDGGNSNYKDNLEQNKLLTEKGIKFFDVG 122
Query: 486 VSGGEDGARYGPSLMPGG-HPAAWPHIKEIFQAI 584
SGG GAR G + M GG +W I+ IF+AI
Sbjct: 123 TSGGMAGARQGGNFMIGGDDEKSWTIIEPIFKAI 156
>UniRef50_Q6N3Q8 Cluster: 6-phosphogluconate dehydrogenase; n=57;
Bacteria|Rep: 6-phosphogluconate dehydrogenase -
Rhodopseudomonas palustris
Length = 346
Score = 90.6 bits (215), Expect = 3e-17
Identities = 53/163 (32%), Positives = 82/163 (50%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
I +IGL MG N++ + G+ ++R +E + A G A L+D+V KL
Sbjct: 3 IGMIGLGRMGGNIVRRLMKDGHHAVVYDRDPQAIETLTREGATG-----AGGLEDLVRKL 57
Query: 300 KRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVG 479
PR + +++ AG + +++L LL+ GD++IDGGN+ + D + K L T I YV
Sbjct: 58 DAPRAVWVMLPAGQITETTIEQLAKLLAAGDVVIDGGNTFWQDDIRRAKTLKETSIDYVD 117
Query: 480 MGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAKANDEP 608
+G SGG G G +M GG A + IF + D P
Sbjct: 118 VGTSGGIWGFERGYCMMIGGDKAVVDRLDPIFATLAPGIGDIP 160
>UniRef50_A0PKN6 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating Gnd2; n=11; root|Rep: 6-phosphogluconate
dehydrogenase, decarboxylating Gnd2 - Mycobacterium
ulcerans (strain Agy99)
Length = 360
Score = 89.0 bits (211), Expect = 8e-17
Identities = 54/168 (32%), Positives = 80/168 (47%)
Frame = +3
Query: 105 QNEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDD 284
+ + + +IGL MG +++ + + G+ ++ V K A G +SL +
Sbjct: 18 RTDMQLGMIGLGRMGADIVRRVVNGGHECVVYDHNPDAV----KAMAGENNTTGVSSLSE 73
Query: 285 MVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTG 464
+ KL PR I ++V AG +++L L GDI+IDGGN+ Y D K K LSG G
Sbjct: 74 LRDKLSAPRVIWVMVPAGTITTGVIEELATTLDAGDIVIDGGNTYYRDDIKHAKLLSGKG 133
Query: 465 ILYVGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAKANDEP 608
I + G SGG G G LM GG P A+ H + I + P
Sbjct: 134 IHMLDCGTSGGVWGLDRGYCLMVGGEPDAFAHAEPILATVAPGVQAAP 181
>UniRef50_Q1IK90 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Acidobacteria bacterium Ellin345|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Acidobacteria bacterium (strain Ellin345)
Length = 211
Score = 85.8 bits (203), Expect = 7e-16
Identities = 51/123 (41%), Positives = 71/123 (57%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
IA+IGL MG N++ + G+ F+R+ ++E + A I A SL D+V KL
Sbjct: 49 IAMIGLGRMGSNMVRRLLRAGHECVVFDRSRQPIDELTRENA-----IPAASLGDVVEKL 103
Query: 300 KRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVG 479
K PR + L+V AG AVD +L+ L GD +IDGGNS Y+D + +EL+ GI YV
Sbjct: 104 KPPRAVWLMVPAG-AVDGTAVELLDFLEPGDTLIDGGNSYYVDDIRRARELALRGIHYVD 162
Query: 480 MGV 488
GV
Sbjct: 163 EGV 165
>UniRef50_Q82ZC2 Cluster: 6-phosphogluconate dehydrogenase family
protein; n=16; Bacteria|Rep: 6-phosphogluconate
dehydrogenase family protein - Enterococcus faecalis
(Streptococcus faecalis)
Length = 299
Score = 84.6 bits (200), Expect = 2e-15
Identities = 52/159 (32%), Positives = 83/159 (52%)
Frame = +3
Query: 117 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSK 296
DI IGL MG N+ LN++++G+ + F+ V+K E +G V+ SL +++
Sbjct: 2 DIGFIGLGKMGLNMALNVHEQGWPIIGFD--VTKEARATARE-QGLSVVD--SLSELLKA 56
Query: 297 LKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYV 476
L + + I L AG ++ V +L+ L+ DII+D GNS + D+ + GI ++
Sbjct: 57 LNKRKVIFLSTPAGQITNQLVAELVEQLAPEDIIVDSGNSNFHDSVANAQLAKEKGIYFI 116
Query: 477 GMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAK 593
G SGG GAR G LM GG P A + F+ + +
Sbjct: 117 DCGTSGGIKGAREGACLMVGGAPEAVKVLTPFFEDLACE 155
>UniRef50_Q9RU02 Cluster: 6-phosphogluconate dehydrogenase; n=24;
Bacteria|Rep: 6-phosphogluconate dehydrogenase -
Deinococcus radiodurans
Length = 368
Score = 82.2 bits (194), Expect = 9e-15
Identities = 50/158 (31%), Positives = 81/158 (51%), Gaps = 3/158 (1%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATS-LDDMVSK 296
I +IGL MG N+++ + + G V F+R+ ++ + ++G TS +D +
Sbjct: 5 IGMIGLGKMGGNMVIRLKNGGQDVVGFDRSQEAIDHLV---SQGVAADALTSDMDRFIEL 61
Query: 297 LKRP--RKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGIL 470
L P R + ++V AG + L LS GD+IIDGGNS + DTQ+ + L+ G+
Sbjct: 62 LGEPGQRAVWVMVPAGQITQSVIDDLAGRLSAGDVIIDGGNSNFHDTQRRGEALAAKGLH 121
Query: 471 YVGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAI 584
+V +G SGG G G +M GG I+ +A+
Sbjct: 122 FVDVGTSGGVWGITEGYGMMVGGPDEGVERIRPALEAL 159
>UniRef50_O66788 Cluster: 6-phosphogluconate dehydrogenase; n=2;
Aquifex aeolicus|Rep: 6-phosphogluconate dehydrogenase -
Aquifex aeolicus
Length = 300
Score = 81.8 bits (193), Expect = 1e-14
Identities = 51/151 (33%), Positives = 83/151 (54%)
Frame = +3
Query: 126 LIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKLKR 305
LIGL MG L + ++G+ + ++RT + E K+ G KV+ + + +
Sbjct: 6 LIGLGRMGSALAYRLKNRGWEIYGYSRTQTTRERAKKD--LGIKVLNSY---ENLKNFPS 60
Query: 306 PRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMG 485
P+ + L+V AVDE ++ L P L+KGD +IDGGNS Y D+Q+ +EL + ++ +G
Sbjct: 61 PKTVWLMVPHT-AVDEVLQNLKPFLNKGDTVIDGGNSYYKDSQRRYRELKEVDVNFLDVG 119
Query: 486 VSGGEDGARYGPSLMPGGHPAAWPHIKEIFQ 578
VSGG G G S M GG + +++F+
Sbjct: 120 VSGGILGKDTGFSFMIGGDEEVFKKHEKLFK 150
>UniRef50_Q7SCJ4 Cluster: Putative uncharacterized protein
NCU00837.1; n=1; Neurospora crassa|Rep: Putative
uncharacterized protein NCU00837.1 - Neurospora crassa
Length = 488
Score = 79.0 bits (186), Expect = 8e-14
Identities = 46/127 (36%), Positives = 63/127 (49%), Gaps = 1/127 (0%)
Frame = +3
Query: 234 KNEAKGTKVIGATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGN 413
K+E K T SL + + +P+ + + G D+ + L P L GDII+D N
Sbjct: 33 KHEDKITYHDDHKSLCEALEDGDKPKVFMFSIPHGGPADDSIDALEPYLKPGDIIMDASN 92
Query: 414 SQYLDTQKWCKELSGTGILYVGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAK 593
+ T++ L GI Y+GMGVSGG AR+GPS+ PGG A + Q I AK
Sbjct: 93 EHWKATERRQARLEPKGIHYIGMGVSGGYQSARHGPSISPGGSKEALDKVFPFLQKIAAK 152
Query: 594 AN-DEPC 611
N PC
Sbjct: 153 DNRGRPC 159
>UniRef50_Q0W2D7 Cluster: Putative 6-phosphogluconate dehydrogenase;
n=1; uncultured methanogenic archaeon RC-I|Rep: Putative
6-phosphogluconate dehydrogenase - Uncultured
methanogenic archaeon RC-I
Length = 310
Score = 76.2 bits (179), Expect = 6e-13
Identities = 48/140 (34%), Positives = 74/140 (52%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
+ +IGL MG +L L +KG V A ++ +F +G + A + ++ L
Sbjct: 3 LGIIGLGRMGGSLALQAVEKGVEVVAHSK--HSHPDFA---TRGIHI--ADTYEEFARLL 55
Query: 300 KRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVG 479
+ PR I L + AG +D+ ++ LIP L +GD+++DGGNS + D+ + L G +
Sbjct: 56 RTPRIIYLSLPAGQIIDQVIESLIPHLERGDVLMDGGNSFFRDSVAREEALRKKGFRLLD 115
Query: 480 MGVSGGEDGARYGPSLMPGG 539
G SGG DGAR G M GG
Sbjct: 116 CGTSGGVDGARTGACFMVGG 135
>UniRef50_Q2LGT9 Cluster: 6-phosphogluconate dehydrogenase; n=6;
Halobacteriaceae|Rep: 6-phosphogluconate dehydrogenase -
Haloquadratum walsbyi
Length = 306
Score = 75.8 bits (178), Expect = 8e-13
Identities = 51/155 (32%), Positives = 79/155 (50%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
+ ++GL MGQ ++ + G+ + AF+ V A A SLD ++ L
Sbjct: 3 LGVVGLGRMGQIVVDRLVTAGHDIVAFDLDAEAVAT-----AADIGATPADSLDTLLDTL 57
Query: 300 KRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVG 479
+++ L+V AG AVD + +L P L++ DII+DGGNS + + + + T Y+
Sbjct: 58 GETKRLWLMVPAGEAVDATLTQLEPSLTETDIIVDGGNSHFEASIRRAETSDAT---YLD 114
Query: 480 MGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAI 584
G SGG GA G SLM GG A+ + +F AI
Sbjct: 115 CGTSGGPAGAELGFSLMIGGQQWAYDELIPVFDAI 149
>UniRef50_Q0V6D4 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 508
Score = 74.9 bits (176), Expect = 1e-12
Identities = 35/89 (39%), Positives = 55/89 (61%), Gaps = 1/89 (1%)
Frame = +3
Query: 348 DEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGVSGGEDGARYGPSL 527
DE ++ L+P L + DII+D GN + +T++ ++ TGI Y+G GVSGG AR GPS+
Sbjct: 71 DEVLQGLMPHLERDDIILDCGNEHFANTERRQHKVKDTGIRYIGCGVSGGYQAARAGPSM 130
Query: 528 MPGGHPAAWPHIKEIFQAICAKAN-DEPC 611
PGG +A + + + + AK ++PC
Sbjct: 131 CPGGDRSALNEVLPLLEKVAAKDKIEKPC 159
>UniRef50_A7QND8 Cluster: Chromosome chr2 scaffold_132, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr2 scaffold_132, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 142
Score = 72.1 bits (169), Expect = 1e-11
Identities = 40/82 (48%), Positives = 54/82 (65%), Gaps = 2/82 (2%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFL-KNEAKG-TKVIGATSLDDMVS 293
I L GLAVMGQNL LN+ +KG+ + +NRT SKV+E L + +G + G S D V
Sbjct: 9 IGLAGLAVMGQNLALNIAEKGFPISVYNRTTSKVDETLDRAHREGHLPLSGHYSPRDFVL 68
Query: 294 KLKRPRKIVLLVKAGFAVDEFV 359
++RPR IV+LVKAG VD+ +
Sbjct: 69 SIQRPRSIVILVKAGAPVDQTI 90
>UniRef50_Q0SAG5 Cluster: Phosphogluconate dehydrogenase; n=23;
Actinobacteria (class)|Rep: Phosphogluconate
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 303
Score = 70.9 bits (166), Expect = 2e-11
Identities = 40/109 (36%), Positives = 58/109 (53%)
Frame = +3
Query: 258 VIGATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQK 437
V SL ++ +L+ PR + ++V AG + V +L +L GD++IDGGNS+Y D +
Sbjct: 35 VTDVASLAELARRLESPRVVWVMVPAGKITQDTVTELSSVLETGDLVIDGGNSRYTDDKV 94
Query: 438 WCKELSGTGILYVGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAI 584
+ L GI Y+ GVSGG G G +M GG A IF A+
Sbjct: 95 HGELLGSRGIGYLDCGVSGGVWGLEDGYGMMVGGSDADVERALPIFDAL 143
>UniRef50_A2Y8G5 Cluster: Putative uncharacterized protein; n=1;
Oryza sativa (indica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. indica
(Rice)
Length = 200
Score = 69.3 bits (162), Expect = 7e-11
Identities = 37/92 (40%), Positives = 56/92 (60%), Gaps = 2/92 (2%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKN-EAKGT-KVIGATSLDDMVS 293
I L GLAVMGQNL LN+ +KG+ + +NRT SKV+E ++ + +G V G V+
Sbjct: 109 IGLAGLAVMGQNLALNIAEKGFPISVYNRTTSKVDETVQRAKVEGNLPVYGFHDPASFVN 168
Query: 294 KLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKG 389
+++PR +++LVKAG VD+ + L G
Sbjct: 169 SIQKPRVVIMLVKAGAPVDQTIGNSCSTLGAG 200
>UniRef50_Q1NQF2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; delta proteobacterium MLMS-1|Rep:
6-phosphogluconate dehydrogenase, NAD-binding - delta
proteobacterium MLMS-1
Length = 178
Score = 66.5 bits (155), Expect = 5e-10
Identities = 36/101 (35%), Positives = 58/101 (57%)
Frame = +3
Query: 105 QNEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDD 284
+ I +IGL MG N+ + G+ V AFNR+ +K EE + A A S+ +
Sbjct: 43 EKRMQIGMIGLGRMGMNMARRLLQGGHQVVAFNRSPAKSEELAQEGATA-----AFSVKE 97
Query: 285 MVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDG 407
+V KL PR + L++ AG VD+ +++L LLS GD++++G
Sbjct: 98 LVGKLAAPRVVWLMLPAGETVDQHLEELAELLSPGDLVVEG 138
>UniRef50_A3PSD9 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating; n=11; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, decarboxylating - Mycobacterium sp.
(strain JLS)
Length = 297
Score = 65.7 bits (153), Expect = 8e-10
Identities = 44/155 (28%), Positives = 71/155 (45%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
+ L+GL MG N+ + + G+ V F+ +V SL + L
Sbjct: 3 LGLVGLGKMGFNMRERLREGGHEVVGFDPR--------------PEVTDVPSLAALADAL 48
Query: 300 KRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVG 479
PR + ++V +G + + L +L +GD++IDGGNS++ + + L GI ++
Sbjct: 49 AAPRVVWVMVPSGPVTHDTIVSLAEVLGEGDLVIDGGNSRFTEDAPHAELLKAKGIGFID 108
Query: 480 MGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAI 584
GVSGG G G LM GG A + IF +
Sbjct: 109 AGVSGGVWGLAEGYGLMVGGDDADIERVMPIFDTL 143
>UniRef50_A6SUL3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Janthinobacterium sp. Marseille|Rep:
2-hydroxy-3-oxopropionate reductase - Janthinobacterium
sp. (strain Marseille) (Minibacterium massiliensis)
Length = 304
Score = 61.3 bits (142), Expect = 2e-08
Identities = 38/141 (26%), Positives = 73/141 (51%), Gaps = 1/141 (0%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
IA +G+ +MG+ + + GY V A+NRT SK +E +GA+ + + +
Sbjct: 10 IAFLGIGLMGKPMASRLLQAGYPVTAWNRTRSKADELAP--------LGASVAERVADAV 61
Query: 300 KRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVG 479
++ +++AG V + + +P L G ++ID +++ + Q+ +L+ G+ ++
Sbjct: 62 AAADIVITMLEAGPIVAQVIDAALPGLKHGALVIDMSSTRQSEAQEVHAKLAAQGVRFID 121
Query: 480 MGVSGGEDGARYGP-SLMPGG 539
VSGG GA G ++M GG
Sbjct: 122 APVSGGVVGAEAGSLAIMAGG 142
>UniRef50_Q3DYV4 Cluster: NADP oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Chloroflexus|Rep: NADP oxidoreductase,
coenzyme F420-dependent:6-phosphogluconate
dehydrogenase, NAD-binding - Chloroflexus aurantiacus
J-10-fl
Length = 289
Score = 58.8 bits (136), Expect = 1e-07
Identities = 48/156 (30%), Positives = 81/156 (51%), Gaps = 1/156 (0%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
IALIGL +MG+ + + G+ V +NR S ++ L +G + AT +++
Sbjct: 3 IALIGLGLMGRPMARTLLKAGFNVTGWNR--SPLDPAL---TEGIP-LAAT-----LAEA 51
Query: 300 KRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVG 479
+ ++L++ AV E + +L PLL +G +IID G+S +Q L+ GI +V
Sbjct: 52 AQAETLILMLSDSTAVAELLSRLDPLLREGQLIIDMGSSDPRHSQTHATTLANRGIGWVD 111
Query: 480 MGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAI 584
VSGG +GA G ++M GG + + I +A+
Sbjct: 112 APVSGGPEGAAAGTLAIMVGGTASDVERAEPILRAL 147
>UniRef50_O66454 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Aquifex aeolicus
Length = 288
Score = 57.2 bits (132), Expect = 3e-07
Identities = 46/157 (29%), Positives = 74/157 (47%), Gaps = 1/157 (0%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
+ IGL +G+ + + ++G + +NRT+SK EF K G +V +S D+++K+
Sbjct: 3 VGFIGLGHLGRAIAKRLIEQGVELIVWNRTLSKAHEFAKE--TGAEV--TSSPADLINKV 58
Query: 300 KRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVG 479
R IV +A V K L+ KG +ID + YL QK +EL G Y+
Sbjct: 59 DRVFVIVFDSQASEEVIFGEKGLVKGDIKGKTVIDMTTNHYLYAQKAYEELKKLGAFYLD 118
Query: 480 MGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAIC 587
V G A G +++ GG + K +F+ C
Sbjct: 119 APVLGSVIPALKGELTIVVGGDKEKFEENKPLFEKFC 155
>UniRef50_Q05FV1 Cluster: 6-phosphogluconate dehydrogenase; n=1;
Candidatus Carsonella ruddii PV|Rep: 6-phosphogluconate
dehydrogenase - Carsonella ruddii (strain PV)
Length = 433
Score = 57.2 bits (132), Expect = 3e-07
Identities = 40/141 (28%), Positives = 69/141 (48%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
I +IG MG+N+ LN+ K + +NR K+ +L + K+I +L ++
Sbjct: 6 IGIIGFGSMGKNISLNLIKKKIFLSVYNR--EKI--YLNKKFFNIKII-TNNLKKFINSF 60
Query: 300 KRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVG 479
+ I++L+K G V + + L+ DI+ID GNS + +T + ++
Sbjct: 61 SNYKIIIILIKPGLPVKNILFLIKDKLNISDILIDFGNSYFKNTYFNFLNIK-KKFSFIS 119
Query: 480 MGVSGGEDGARYGPSLMPGGH 542
G+SGG +GA G LM G+
Sbjct: 120 AGISGGSEGALRGLCLMIDGN 140
>UniRef50_A5LYV4 Cluster: 6-phosphogluconate dehydrogenase; n=1;
Streptococcus pneumoniae SP11-BS70|Rep:
6-phosphogluconate dehydrogenase - Streptococcus
pneumoniae SP11-BS70
Length = 96
Score = 57.2 bits (132), Expect = 3e-07
Identities = 24/74 (32%), Positives = 48/74 (64%)
Frame = +3
Query: 111 EADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMV 290
+A+ ++G+AVMG+NL LN+ +GY V +NR+ K E+ + + + + ++ V
Sbjct: 3 KANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIACHPE-KNFVPSYDVESFV 61
Query: 291 SKLKRPRKIVLLVK 332
+ +++PR+I+L+VK
Sbjct: 62 NSIEKPRRIMLMVK 75
>UniRef50_A7R419 Cluster: Chromosome undetermined scaffold_607,
whole genome shotgun sequence; n=1; Vitis vinifera|Rep:
Chromosome undetermined scaffold_607, whole genome
shotgun sequence - Vitis vinifera (Grape)
Length = 209
Score = 57.2 bits (132), Expect = 3e-07
Identities = 28/67 (41%), Positives = 40/67 (59%), Gaps = 1/67 (1%)
Frame = +3
Query: 405 GGNSQYLDTQKWCKELSGT-GILYVGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQA 581
GG+ ++ K+ + G Y+GMGVSG E+GAR+GPSL PGG A HI++I
Sbjct: 69 GGSGNFIKMHSPIKKATAELGPFYLGMGVSGDEEGARHGPSLTPGGSSKAHKHIEDILLK 128
Query: 582 ICAKAND 602
A+ +D
Sbjct: 129 RAAQVSD 135
Score = 52.8 bits (121), Expect = 6e-06
Identities = 25/53 (47%), Positives = 34/53 (64%)
Frame = +3
Query: 444 KELSGTGILYVGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAKAND 602
K + G Y+GMGVSG E+GAR+GPSL PGG A +I++I A+ +D
Sbjct: 6 KATAKLGPFYLGMGVSGDEEGARHGPSLTPGGSSKAHKNIEDILLKRAAQVSD 58
>UniRef50_A7ES77 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 329
Score = 54.8 bits (126), Expect = 2e-06
Identities = 25/53 (47%), Positives = 32/53 (60%), Gaps = 1/53 (1%)
Frame = +3
Query: 456 GTGILYVGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAKAND-EPC 611
G G+ Y+G GVSGG AR GPS+ PGG A + + + I AKA+D PC
Sbjct: 129 GNGVFYIGCGVSGGYQAARRGPSMCPGGQEQALDIVMPLLEKIAAKASDGTPC 181
>UniRef50_Q41DK0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Bacillaceae|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Exiguobacterium sibiricum
255-15
Length = 293
Score = 53.2 bits (122), Expect = 5e-06
Identities = 44/158 (27%), Positives = 77/158 (48%), Gaps = 3/158 (1%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVI--GATSLDDMVS 293
I IGL VMGQ ++ N+ G+ V +NRT K ++ A I T +D ++S
Sbjct: 5 IGFIGLGVMGQGMVRNLLKAGFSVKGYNRTKEKGLPLEQDGAVIVDTIQEAVTDVDVVIS 64
Query: 294 KLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILY 473
+ P+ + + A D + P G I+ID S + ++ + TG+
Sbjct: 65 IVGYPQDVEEIY---LAEDGILASANP----GTIVIDMTTSSPALAIRIAEQAAQTGLHA 117
Query: 474 VGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAI 584
+ V+GG+ GA+ G +++ GG AA+ +K +F+A+
Sbjct: 118 LDAPVTGGDLGAKNGTLAILVGGEEAAFDTVKPLFEAM 155
>UniRef50_Q97XZ7 Cluster: Oxidoreductase; n=6; Thermoprotei|Rep:
Oxidoreductase - Sulfolobus solfataricus
Length = 289
Score = 53.2 bits (122), Expect = 5e-06
Identities = 43/159 (27%), Positives = 77/159 (48%), Gaps = 4/159 (2%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
+ IGL +MG + N+ GY + +NRT+ K E+ K G KV + VS++
Sbjct: 3 VGFIGLGIMGFPMASNLLKAGYDLTVYNRTIEKAEKLGK---MGAKVAHSPKEVAEVSEI 59
Query: 300 KRPRKIVLLVKAGFAVDEFV---KKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGIL 470
++ +V V+E + ++ +G I +D + +K K LS G+
Sbjct: 60 -----VISMVTDAPDVEEVLFGENGVVKSNKRGLIFVDMSTNSPEFAKKVTKRLSEYGME 114
Query: 471 YVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAI 584
++ V+GG+ GAR G ++M GG + ++ IF+A+
Sbjct: 115 FLDAPVTGGDKGAREGTLTIMVGGKEDVFKRVEPIFKAM 153
>UniRef50_A4IN46 Cluster: 3-hydroxyisobutyrate dehydrogenase-like
protein; n=2; Geobacillus|Rep: 3-hydroxyisobutyrate
dehydrogenase-like protein - Geobacillus
thermodenitrificans (strain NG80-2)
Length = 304
Score = 51.2 bits (117), Expect = 2e-05
Identities = 37/159 (23%), Positives = 70/159 (44%), Gaps = 3/159 (1%)
Frame = +3
Query: 117 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIG--ATSLDDMV 290
++ IGL +MG + + D G+ V +NRT K +++ A+ + I A+ +D +
Sbjct: 3 NVGFIGLGMMGSRMAKRLLDAGFPVTVYNRTPEKAAILVESGARQAETIAALASEVDVIC 62
Query: 291 SKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGIL 470
+ L P ++ + V + +G I +D ++ G+
Sbjct: 63 TCLSMPDDVINVYTGEGGV-------LSAARRGVICLDFTTVGPKTSRFVAGRAGERGVA 115
Query: 471 YVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAI 584
Y+ VSGG +GA G ++M GG AAW ++ + +
Sbjct: 116 YLDAPVSGGPEGAEQGTLTIMVGGDQAAWERVRPLLSVL 154
>UniRef50_A2Y8G6 Cluster: 6-phosphogluconate dehydrogenase,
decarboxylating; n=1; Oryza sativa (indica
cultivar-group)|Rep: 6-phosphogluconate dehydrogenase,
decarboxylating - Oryza sativa subsp. indica (Rice)
Length = 446
Score = 50.4 bits (115), Expect = 3e-05
Identities = 25/45 (55%), Positives = 33/45 (73%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGT 254
I L GLAVMGQNL LN+ +KG+ + +NRT SKV+E ++ AK T
Sbjct: 6 IGLAGLAVMGQNLALNIAEKGFPISVYNRTTSKVDETVQG-AKHT 49
Score = 39.9 bits (89), Expect = 0.048
Identities = 20/47 (42%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
Frame = +3
Query: 474 VGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAKANDE-PC 611
+GM +GAR GPSLMPGG A+ +I++I + A+ D PC
Sbjct: 82 LGMVFPEEREGARNGPSLMPGGSFEAYKYIEDILLKVAAQVPDSGPC 128
>UniRef50_Q18X68 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Desulfitobacterium hafniense|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Desulfitobacterium hafniense (strain DCB-2)
Length = 298
Score = 48.4 bits (110), Expect = 1e-04
Identities = 40/159 (25%), Positives = 71/159 (44%), Gaps = 1/159 (0%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
+ IGL MG+++ LN+ G + +++ + EF + A+ I + D++
Sbjct: 3 LGFIGLGQMGKHMALNLLKSGEELIVYDQRPASYPEFEQRGARTAAQIRDVAEADIIFCS 62
Query: 300 KRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVG 479
++V V G + +KK+ L G II+D Y T + K+L G+ ++
Sbjct: 63 LPNSEVVCQVVLG---ETGLKKV---LRAGQIIVDTSTINYSTTLEIGKQLESVGVEFID 116
Query: 480 MGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAICAK 593
VSG E A+ G + M GG + ++K Q K
Sbjct: 117 APVSGMESRAKEGTLTTMCGGKQELFENVKPYLQCFADK 155
>UniRef50_Q73P00 Cluster: 3-hydroxyacid dehydrogenase family
protein; n=4; Bacteria|Rep: 3-hydroxyacid dehydrogenase
family protein - Treponema denticola
Length = 292
Score = 47.6 bits (108), Expect = 2e-04
Identities = 46/163 (28%), Positives = 65/163 (39%), Gaps = 4/163 (2%)
Frame = +3
Query: 99 MPQNEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSL 278
M D+ IGL VMG+++ + G + F RT EE L GA
Sbjct: 1 MKVENCDVGFIGLGVMGKSMAERLRAAGAKMHVFTRTKKSAEEILSK--------GAIWY 52
Query: 279 DDMVSKLKRPRKIVLLVKAGFAVDEFV---KKLIPLLSKGDIIIDGGNSQYLDTQKWCKE 449
DD S + I +V V+E K L+ G I D S + +K E
Sbjct: 53 DDPASLAPNCKIIFTIVGYPQDVEETYFGEKGLLKTAKPGTIFADMTTSSPILAKKIYDE 112
Query: 450 LSGTGILYVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIF 575
V VSGG+ GA+ G S+M GG +A+ ++ F
Sbjct: 113 AKKKECFSVDAPVSGGDIGAKNGTLSIMAGGDESAFKELEPFF 155
>UniRef50_Q47AR2 Cluster: NADP oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Dechloromonas aromatica RCB|Rep: NADP
oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding - Dechloromonas aromatica (strain RCB)
Length = 287
Score = 47.6 bits (108), Expect = 2e-04
Identities = 43/157 (27%), Positives = 73/157 (46%), Gaps = 2/157 (1%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
I IGL +MG+ + LN+ G+ V + R ++ L AK GA S ++
Sbjct: 3 IGFIGLGIMGRPMALNLIKGGHQVTVWARRAESMQPLLDAGAK-----GAAS----PAEA 53
Query: 300 KRPRKIVL-LVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYV 476
R ++V+ +V V E ++ + G + +D ++ ++L+ GI ++
Sbjct: 54 ARGNELVISMVADAPDVAEVMRGVASAGESGLVAVDMSTIAPAAARRIGEDLAAAGIDFI 113
Query: 477 GMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAI 584
VSGGE GA G S+M GG AA+ K F+ +
Sbjct: 114 DAPVSGGEVGAIAGSLSIMAGGSDAAFAKAKPAFECM 150
>UniRef50_Q0F1Y7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein; n=1; Mariprofundus ferrooxydans
PV-1|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
protein - Mariprofundus ferrooxydans PV-1
Length = 289
Score = 47.6 bits (108), Expect = 2e-04
Identities = 41/148 (27%), Positives = 69/148 (46%), Gaps = 3/148 (2%)
Frame = +3
Query: 117 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSK 296
+I IGL +MG+ + N+ +G+ + +NRTV K + G V SL S
Sbjct: 4 NIGFIGLGIMGEAMAANILKQGHPLIVYNRTVEKAAALVD---AGAMVADKPSLVADASD 60
Query: 297 LKRPRKIVLLVKAGFAVDEFVKKLIPLLS---KGDIIIDGGNSQYLDTQKWCKELSGTGI 467
+ I+L++ AVD + LLS +G +I+ +++W KEL+ G+
Sbjct: 61 V-----IILMLTGEEAVDAVLFGEEGLLSGDCEGKTVINMSTVPVECSKRWAKELADHGM 115
Query: 468 LYVGMGVSGGEDGARYGPSLMPGGHPAA 551
+ VSG + A+ G ++ G P A
Sbjct: 116 TLIDAPVSGSKVPAQTGTLVILAGGPEA 143
>UniRef50_Q97ZE5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4;
Sulfolobaceae|Rep: 3-hydroxyisobutyrate dehydrogenase -
Sulfolobus solfataricus
Length = 289
Score = 47.6 bits (108), Expect = 2e-04
Identities = 32/95 (33%), Positives = 50/95 (52%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
I LIGL +MG + N+ + ++RT K+E F+K KV G + D+V
Sbjct: 3 IGLIGLGIMGYRIAANLAKANKLNLVYDRTQEKIESFVKE----YKVNGVQNTKDLV--- 55
Query: 300 KRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIID 404
+ I+ ++ +AV V+ LIPL+ KG I+ID
Sbjct: 56 ESSDVIITMLADDYAVKSVVEPLIPLM-KGKILID 89
>UniRef50_A4SWE8 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=7; Proteobacteria|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 299
Score = 47.2 bits (107), Expect = 3e-04
Identities = 45/156 (28%), Positives = 79/156 (50%), Gaps = 4/156 (2%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
+ IGL +MG + ++ G+ + F T SKV E L N A V+ AT + V+K+
Sbjct: 6 LGFIGLGIMGAPMASHLMAAGHAL--FINTRSKVPEELANSAA---VVCATPAE--VAKM 58
Query: 300 KRPRKIVLLVKAGFAVDEFV---KKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGIL 470
I +V V++ + + LSKG I++D + + T+ + K+++ G
Sbjct: 59 ADI--IFTMVPDTPDVEKVLFGEHGVAHGLSKGKIVVDMSSISPIATKDFAKKINALGCE 116
Query: 471 YVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIF 575
Y+ VSGG+ GA+ G ++M GG + + +K +F
Sbjct: 117 YLDAPVSGGQVGAKGGTLTIMVGGKESVFQTVKPMF 152
>UniRef50_P77161 Cluster: 2-hydroxy-3-oxopropionate reductase; n=99;
Proteobacteria|Rep: 2-hydroxy-3-oxopropionate reductase
- Escherichia coli (strain K12)
Length = 292
Score = 47.2 bits (107), Expect = 3e-04
Identities = 40/159 (25%), Positives = 76/159 (47%), Gaps = 4/159 (2%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
+ IGL +MG + +N+ G+ + T+ V + L + +GA S++
Sbjct: 3 LGFIGLGIMGTPMAINLARAGHQLHV--TTIGPVADELLS-------LGAVSVETARQVT 53
Query: 300 KRPRKIVLLVKAGFAVDEFV---KKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGIL 470
+ I ++V V+E + KG I+D + ++T+++ ++++ G
Sbjct: 54 EASDIIFIMVPDTPQVEEVLFGENGCTKASLKGKTIVDMSSISPIETKRFARQVNELGGD 113
Query: 471 YVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAI 584
Y+ VSGGE GAR G S+M GG A + +K +F+ +
Sbjct: 114 YLDAPVSGGEIGAREGTLSIMVGGDEAVFERVKPLFELL 152
>UniRef50_Q67QX0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: 3-hydroxyisobutyrate
dehydrogenase - Symbiobacterium thermophilum
Length = 294
Score = 46.8 bits (106), Expect = 4e-04
Identities = 36/156 (23%), Positives = 69/156 (44%), Gaps = 1/156 (0%)
Frame = +3
Query: 114 ADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVS 293
A++ IGL MG+++ N+ G+ V +NR+ + V+E + G + G +
Sbjct: 3 ANLGFIGLGRMGRHMARNLIRAGHTVTLYNRSQAVVDELVAE--GGRRAAGPAEV----- 55
Query: 294 KLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILY 473
+ R + + V+ +++ + GDI +D D ++ + G+ +
Sbjct: 56 -ARDARVLFTCLTTPDVVESILRQALEGAQPGDIFVDHSTIGVRDAKRIAAMCAEKGVQF 114
Query: 474 VGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQ 578
+ VSGG GA G ++M GG AA+ + Q
Sbjct: 115 IDAPVSGGPWGAEAGTLTIMCGGDRAAFEAVLPYLQ 150
>UniRef50_Q03UI4 Cluster: 3-hydroxyisobutyrate dehydrogenase related
enzyme; n=2; Lactobacillales|Rep: 3-hydroxyisobutyrate
dehydrogenase related enzyme - Leuconostoc mesenteroides
subsp. mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 287
Score = 46.8 bits (106), Expect = 4e-04
Identities = 44/159 (27%), Positives = 67/159 (42%), Gaps = 3/159 (1%)
Frame = +3
Query: 117 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEA--KGTKVIGATSLDDMV 290
+I IG VMG +I N+ GY V FNRT SK L N A + T A D
Sbjct: 2 NIGFIGTGVMGTGIINNLLQAGYEVSVFNRTHSKANTVLNNGAIWRDTPAKVAQYSDITF 61
Query: 291 SKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGIL 470
+ + P+ + + + V K +G I++D S ++ + + G
Sbjct: 62 TMVGYPKDVEEVWTSEDGVFAGAK-------EGSILVDMTTSTPRLAEQLAQTGADLGFK 114
Query: 471 YVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAI 584
+ VSGG+ GA+ G ++M GG IK + I
Sbjct: 115 VLDAPVSGGDIGAKNGTLAIMVGGEQQVLDEIKPVLSVI 153
>UniRef50_Q8UBW3 Cluster: Oxidoredutase; n=1; Agrobacterium
tumefaciens str. C58|Rep: Oxidoredutase - Agrobacterium
tumefaciens (strain C58 / ATCC 33970)
Length = 300
Score = 46.4 bits (105), Expect = 6e-04
Identities = 40/160 (25%), Positives = 73/160 (45%), Gaps = 3/160 (1%)
Frame = +3
Query: 105 QNEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDD 284
+ + +A IG +MG + + G+ V +NR+V K + + + A V+ A+ +
Sbjct: 7 EKKRSVAFIGTGLMGGPMARRLLGTGFSVKVWNRSVDKAQALVADGA----VLAASPAE- 61
Query: 285 MVSKLKRPRKIVLLVKAGFAVDE--FVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSG 458
+ ++ ++ G AV E F + L+KG ++ID + ++ L
Sbjct: 62 ---AARGADIVITMLSDGNAVGEVLFEAGVAEALAKGAVVIDSSSIAPPIAREHSSRLQA 118
Query: 459 TGILYVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIF 575
GI +V VSGG GA G ++M GG A + ++F
Sbjct: 119 MGIHHVDAPVSGGVPGATAGTLAIMAGGDEALISGLVDVF 158
>UniRef50_Q6UCZ9 Cluster: Predicted oxidoreductase; n=2;
environmental samples|Rep: Predicted oxidoreductase -
uncultured marine proteobacterium ANT32C12
Length = 309
Score = 46.4 bits (105), Expect = 6e-04
Identities = 42/155 (27%), Positives = 74/155 (47%), Gaps = 4/155 (2%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
I IGL VMG + +++ + +C FNR+ KV ++L N+ G T+ D
Sbjct: 23 IGFIGLGVMGYPMAGHLSKEFSNICIFNRSQEKVTKWL-NQYSG------TAFDTPEELS 75
Query: 300 KRPRKIVLLVKAGFAVDEFV---KKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGIL 470
+ I L V V E + K ++ ++ G IIID + +++ + ++
Sbjct: 76 SQCNVIALCVGRDEDVREMMSGKKGILNSVNPGTIIIDHTTTSATLSKEMNELALQKDVI 135
Query: 471 YVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEI 572
++ +SGG+ GA G S+M GG A++ +K I
Sbjct: 136 FLDAPISGGQAGAESGQLSVMVGGDKASYESVKPI 170
>UniRef50_A6NVP0 Cluster: Putative uncharacterized protein; n=1;
Bacteroides capillosus ATCC 29799|Rep: Putative
uncharacterized protein - Bacteroides capillosus ATCC
29799
Length = 306
Score = 46.4 bits (105), Expect = 6e-04
Identities = 46/158 (29%), Positives = 67/158 (42%), Gaps = 3/158 (1%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
I IGL MG+ + N+ GY V AF+ + V+E E KG IG S +M +
Sbjct: 8 IGFIGLGAMGRPMATNLLTAGYEVHAFDVVEAAVKEM---EGKGA--IGHPSAGEMAGHV 62
Query: 300 KRPRKIVLLVKAGFAVDEFVKK--LIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILY 473
I L A K + +G +IID + T+ K+ + GI Y
Sbjct: 63 DVI--ICSLPNAKIVEGTMCGKNGVFENCKEGTVIIDMSSVAPNTTKAMAKKAAEKGIHY 120
Query: 474 VGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAI 584
+ VSGG GA G ++M G + +K IF +
Sbjct: 121 IDAPVSGGVSGAAAGTLTIMVGADDETFNKVKPIFDVL 158
>UniRef50_A3X9R7 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=2; Rhodobacterales|Rep: 3-hydroxyisobutyrate
dehydrogenase family protein - Roseobacter sp. MED193
Length = 300
Score = 46.0 bits (104), Expect = 7e-04
Identities = 40/159 (25%), Positives = 71/159 (44%), Gaps = 1/159 (0%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
I L+GL MG + + + + F+ + E + A G KV A SL D +
Sbjct: 17 IGLVGLGAMGGGYLSRLMAQNCDLMCFD---AMPEARARAAAAGAKV--ADSLADFSAC- 70
Query: 300 KRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVG 479
++L + V +++L P L KG I++D S+ T++ G ++
Sbjct: 71 ---DTVILSLPKAAIVSAVMEELGPYLKKGSIVVDTSTSEPDTTKRLAAAAESNGYTFLD 127
Query: 480 MGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAICAK 593
VSGG GAR G +++ GG A + ++ + + + K
Sbjct: 128 GPVSGGPLGARTGTMTMVVGGDEAGFTKVRPLLEKMTGK 166
>UniRef50_Q7VYY0 Cluster: Putative oxidoreductase; n=4;
Bordetella|Rep: Putative oxidoreductase - Bordetella
pertussis
Length = 305
Score = 45.6 bits (103), Expect = 0.001
Identities = 37/161 (22%), Positives = 74/161 (45%), Gaps = 4/161 (2%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNM-NDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVS- 293
+ +GL +MG ++ N+ D+ + + A++R+ + E + A G ++ A L ++ +
Sbjct: 5 LGFVGLGMMGLPMLENLAGDERWQILAYDRSPAPFERLAGHPAWGKRLRAAAGLQELAAC 64
Query: 294 -KLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGIL 470
+ + A + LI LL G I+D G+S DT++ ++L+ G+
Sbjct: 65 DTVITMLPNSAITNAVVLGGDGQPGLIDLLESGAAIVDMGSSNPADTRRLSEQLAARGLT 124
Query: 471 YVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAICA 590
+ VSG A G ++M G A ++ I + + A
Sbjct: 125 LIDAPVSGAVAKASTGTLAIMAGAAEADLRRVRPILERMGA 165
>UniRef50_A1UP64 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mycobacterium sp. (strain
KMS)
Length = 305
Score = 45.6 bits (103), Expect = 0.001
Identities = 46/162 (28%), Positives = 73/162 (45%), Gaps = 4/162 (2%)
Frame = +3
Query: 117 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSK 296
++ IGL VMG+ + ++ D G+ V FNR+ +KV+E EA+G +GATS K
Sbjct: 2 NVGFIGLGVMGKPMAGHLVDAGHHVVVFNRSRAKVDEL---EARG--AVGATSPAHAGEK 56
Query: 297 LKRPRKIVLLVKAGFAVDEFV---KKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGI 467
++ ++ V+E + + L G ++ID L+ I
Sbjct: 57 AD---VVITMLPDSPEVEEVLFGPAGVTTTLRPGSLVIDCSTISPDAAVAIGARLAEKDI 113
Query: 468 LYVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAICA 590
+V VSGGE GA G ++M GG A + A+ A
Sbjct: 114 AFVDAPVSGGEAGAIAGALAVMMGGDEDAVRRAATVLDAVAA 155
>UniRef50_Q5L168 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=15;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Geobacillus kaustophilus
Length = 288
Score = 45.2 bits (102), Expect = 0.001
Identities = 44/158 (27%), Positives = 70/158 (44%), Gaps = 3/158 (1%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEA--KGTKVIGATSLDDMVS 293
I IGL VMG+++ ++ GY + A+ RT K E+ L+ A K T A D +++
Sbjct: 4 IGFIGLGVMGKSMARHLLKAGYPLLAYTRTKEKAEDLLQEGAVWKETVADLAREADVVMT 63
Query: 294 KLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILY 473
+ PR + + F ++ P G +ID S Q + GI
Sbjct: 64 MVGDPRDV---EQVYFGEGGILENARP----GTYVIDMTTSTPTLAQSIYEAAKQKGIHA 116
Query: 474 VGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAI 584
+ VSGG+ GAR G ++M GG + K I + +
Sbjct: 117 LDAPVSGGDIGAREGTLTIMVGGDEDVFLACKPILERL 154
>UniRef50_A6P2M7 Cluster: Putative uncharacterized protein; n=2;
Bacteria|Rep: Putative uncharacterized protein -
Bacteroides capillosus ATCC 29799
Length = 321
Score = 45.2 bits (102), Expect = 0.001
Identities = 40/156 (25%), Positives = 74/156 (47%), Gaps = 1/156 (0%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
IA IG+ +MG++++ N+ GY + ++RT +K E+ + A+G + A ++ D V
Sbjct: 38 IAFIGVGIMGKSMVRNLMKAGYSLTIYSRTKAKCEDVI---AEG--AVWADTVADCVRDA 92
Query: 300 KRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVG 479
+ IV K V +I G +I+D S ++ + G+ +
Sbjct: 93 EAVFSIVGYPKDVEEVYFGDGGIISNAQPGALIVDMTTSSPALAERIWEAGKAKGLRPLD 152
Query: 480 MGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAI 584
V+GG+ GA+ G S++ GG + +FQA+
Sbjct: 153 APVTGGDTGAKAGTLSILVGGDKVDFDACLPLFQAM 188
>UniRef50_Q606G9 Cluster: Oxidoreductase, Gfo/Idh/MocA family; n=6;
Proteobacteria|Rep: Oxidoreductase, Gfo/Idh/MocA family
- Methylococcus capsulatus
Length = 289
Score = 44.8 bits (101), Expect = 0.002
Identities = 41/153 (26%), Positives = 63/153 (41%), Gaps = 1/153 (0%)
Frame = +3
Query: 129 IGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKLKRP 308
+GL MG + N+ G + +NRT K F A T +L +M
Sbjct: 6 VGLGAMGLGMARNLRRAGLLAGVWNRTPEKARAF----AAETGTPAWATLTEMAPACD-- 59
Query: 309 RKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVGMGV 488
IV V A V E + L P L G +I+D ++ + + G ++ V
Sbjct: 60 -VIVTCVSADADVLEVIAALTPGLRPGAVIVDCSTVGVATARRAAEVVRQAGGDFLDAPV 118
Query: 489 SGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAI 584
SGG +GAR G +LM GG ++ + A+
Sbjct: 119 SGGVEGARDGTLALMIGGRAETVEKVRPVLAAM 151
>UniRef50_Q1AVA4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=6;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 309
Score = 44.8 bits (101), Expect = 0.002
Identities = 41/160 (25%), Positives = 70/160 (43%), Gaps = 5/160 (3%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLK----NEAKGTKVIGATSLDDM 287
+ IGL +MG+ + N+ GY + NRT K EEF + AK K + S D +
Sbjct: 17 VGFIGLGIMGRPMAENLIRAGYSLTVHNRTHQKAEEFAQQTGARTAKSPKEVAGQS-DII 75
Query: 288 VSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGI 467
++ L + +V V E ++ +G ++ID ++ + G
Sbjct: 76 ITMLPDSPDVESVVAGEGGVLEGMR-------EGSLLIDMSTISPAVARQLAAKARERGA 128
Query: 468 LYVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAI 584
+ VSGG+ GAR G S+M GG + + +F+ +
Sbjct: 129 SMLDAPVSGGDVGAREGTLSIMVGGSEEDFGRARPLFEVM 168
>UniRef50_Q92D17 Cluster: Lin1004 protein; n=10; Bacilli|Rep:
Lin1004 protein - Listeria innocua
Length = 286
Score = 44.4 bits (100), Expect = 0.002
Identities = 42/160 (26%), Positives = 71/160 (44%), Gaps = 5/160 (3%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGA--TSLDDMVS 293
I +G VMG ++ ++ + GY V + RT K E L A G+ +D ++S
Sbjct: 4 IGFVGTGVMGSSMAKHLLEAGYEVHIYTRTKEKAEALLSQGALWESDPGSLGAKVDILIS 63
Query: 294 KLKRPRKI--VLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGI 467
+ P+ + + L + GF + L G + ID S +K + GI
Sbjct: 64 MVGYPKDVEQLYLGENGF---------LDNLKAGSVAIDMTTSSPALAKKIAEAGHEKGI 114
Query: 468 LYVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAI 584
+ VSGG+ GA+ G ++M GG + +K IF+ +
Sbjct: 115 GVLDAPVSGGDIGAKNGTLAIMVGGAEDVFLKVKPIFEIL 154
>UniRef50_Q89M84 Cluster: Blr4309 protein; n=6;
Bradyrhizobiaceae|Rep: Blr4309 protein - Bradyrhizobium
japonicum
Length = 293
Score = 44.4 bits (100), Expect = 0.002
Identities = 40/144 (27%), Positives = 62/144 (43%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
+A IGL MG + D G+ V +NR+ +K E+ + A+G ATS +D
Sbjct: 4 VAFIGLGRMGHGMAGRYLDAGFTVTLWNRSKTKAEDLI---ARGAH--WATSPEDAAIDA 58
Query: 300 KRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVG 479
+V +A AV K G I I+ Y ++ +EL+ G++Y+
Sbjct: 59 DAVVTMVADDEASRAVWLGPKGAAKTAKAGTIAIECSTVSYDHAREMGRELNARGLIYID 118
Query: 480 MGVSGGEDGARYGPSLMPGGHPAA 551
V+G D A G + G AA
Sbjct: 119 CPVTGLPDAAAAGKLTLLVGADAA 142
>UniRef50_Q629W3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=21;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Burkholderia mallei (Pseudomonas mallei)
Length = 295
Score = 44.4 bits (100), Expect = 0.002
Identities = 38/160 (23%), Positives = 65/160 (40%), Gaps = 4/160 (2%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
+ +GL VMGQ + LN+ G + +NRT + E + GA D
Sbjct: 3 LGFVGLGVMGQPMALNLARAGTELVVWNRTRERCEPL--------RAAGAQVADSAADVY 54
Query: 300 KRPRKIVLLVKAGFAVDEFVKKLIPLLSKG---DIIIDGGNSQYLDTQKWCKELSGTGIL 470
+R R ++L++ A+D + + P + I+ G ++ ++ G
Sbjct: 55 RRARIVILMMATDAAIDAVLDRGKPAFASNVAQHTIVQMGTVSAEYSRGLEADIRAAGGR 114
Query: 471 YVGMGVSGGEDGARYGPSL-MPGGHPAAWPHIKEIFQAIC 587
YV VSG A G + M G PAA ++ + +C
Sbjct: 115 YVEAPVSGSRQPAEAGRLVAMLAGEPAAVEEVRALLAPMC 154
>UniRef50_A6LT11 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Clostridiales|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Clostridium beijerinckii
NCIMB 8052
Length = 291
Score = 44.4 bits (100), Expect = 0.002
Identities = 45/159 (28%), Positives = 70/159 (44%), Gaps = 4/159 (2%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
I IG+ VMG++++ N+ KGY V + RT KV + + NE GA DD+ S
Sbjct: 4 IGFIGVGVMGKSMVRNLMKKGYEVSIYTRTKEKVLDVI-NE-------GAKWCDDVKSCA 55
Query: 300 KRPRKIVLLVKAGFAVDEFV---KKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGIL 470
I+ +V V+E ++ K IID + + K E I
Sbjct: 56 NNRDVIITIVGYPKDVEEVYFGENGILENAKKESCIIDMTTTSPKLSIKIYNEAKKREIY 115
Query: 471 YVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAI 584
+ VSGG+ GA+ S+M GG + K++ A+
Sbjct: 116 ALDAPVSGGDVGAKNATLSIMVGGDLEVFEKHKDVLSAL 154
>UniRef50_Q8F4I7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4;
Leptospira|Rep: 3-hydroxyisobutyrate dehydrogenase -
Leptospira interrogans
Length = 296
Score = 43.6 bits (98), Expect = 0.004
Identities = 41/164 (25%), Positives = 73/164 (44%), Gaps = 2/164 (1%)
Frame = +3
Query: 108 NEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDM 287
N+ I++IG +MG+ + +N+ G+ + + R +SK+++ K+ + D
Sbjct: 3 NKYTISIIGTGIMGRGMAVNLAKAGHSLRLYTRNLSKIQDLKKDNVQ--------IFDSP 54
Query: 288 VSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGI 467
+ K +VL + V++ L +K I+ID G + T K K S I
Sbjct: 55 IEAAKNSDLVVLCLTEDQIVEKETISSGLLDTKPPILIDCGTTSLSLTLKLSKLCSEKKI 114
Query: 468 LYVGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEI--FQAICAK 593
+ ++G ++ AR G L G A IK+I F +C K
Sbjct: 115 RFYDSPMTGSKNAARDGQILFMIG--AKQVDIKDIQFFFEVCGK 156
>UniRef50_Q89R44 Cluster: Oxidoreductase; n=23; Bacteria|Rep:
Oxidoreductase - Bradyrhizobium japonicum
Length = 305
Score = 43.6 bits (98), Expect = 0.004
Identities = 41/166 (24%), Positives = 72/166 (43%), Gaps = 3/166 (1%)
Frame = +3
Query: 105 QNEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTK--VIGATSL 278
QN+ IA++GL MG + ++ G+ V + + V F+K+ G K A
Sbjct: 7 QNQR-IAVVGLGSMGFGMATSLKRAGHAVTGCDVSADAVARFVKDGGAGAKTPAEAARGA 65
Query: 279 DDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSG 458
D +VS + + ++ F D V + +P K + + ++ K+L
Sbjct: 66 DVVVSVVVNAAQTETIL---FGKDG-VAETMP---KDSVFLSSATMDPDVARRLAKQLEA 118
Query: 459 TGILYVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAICAK 593
TG Y+ +SGG A G +++ G PAA+ + A+ AK
Sbjct: 119 TGRHYLDAPISGGAQRAAQGELTILASGSPAAFAKARPALDAMAAK 164
>UniRef50_Q4FMJ3 Cluster: 6-phosphogluconate dehydrogenase; n=2;
Candidatus Pelagibacter ubique|Rep: 6-phosphogluconate
dehydrogenase - Pelagibacter ubique
Length = 289
Score = 43.6 bits (98), Expect = 0.004
Identities = 38/144 (26%), Positives = 73/144 (50%), Gaps = 3/144 (2%)
Frame = +3
Query: 117 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSK 296
+I+ IG+ +MG + N+ G+ + A+NR+ K + + G ++ +TS+ D+V+
Sbjct: 3 NISFIGIGLMGFPMAKNLLKSGFNLRAYNRSQDKADRL---KEFGAEI--STSIKDVVT- 56
Query: 297 LKRPRKIVLLVKAGFAVDEFV--KKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGIL 470
I+ ++ AV++ + + I + +G +ID + + T+K+ K L I
Sbjct: 57 --NSDVIITMLTDDAAVEKVMGSDEFISNIKEGATVIDMSSVNPVITKKYFKILKEKNIN 114
Query: 471 YVGMGVSGGEDGARYGP-SLMPGG 539
Y+ VSGG GA ++M GG
Sbjct: 115 YLDAPVSGGTIGAEEASLAIMVGG 138
>UniRef50_A5V0D4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Chloroflexaceae|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Roseiflexus sp. RS-1
Length = 303
Score = 43.6 bits (98), Expect = 0.004
Identities = 45/167 (26%), Positives = 73/167 (43%), Gaps = 5/167 (2%)
Frame = +3
Query: 99 MPQNEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIG--AT 272
M Q E + IGL +MG+ + N+ G+ + +NRT S+++E A G A
Sbjct: 1 MDQRER-VGFIGLGIMGRGMARNILKAGFPLRVWNRTASRMDELAAEGAGPASSPGDLAF 59
Query: 273 SLDDMVSKLKRPRKI--VLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 446
D +++ + + VLL + G +I G ++ID TQ+
Sbjct: 60 HSDIIITCVSDTPDVEQVLLGEGG---------VIHGARPGSLVIDMSTISPRATQRIAA 110
Query: 447 ELSGTGILYVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAI 584
L+ I + VSGG +GA G S+M GG + +FQA+
Sbjct: 111 HLAERHIHMLDAPVSGGSEGAARGTLSIMVGGDVTQFERALPVFQAM 157
>UniRef50_A7IE35 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Xanthobacter sp. (strain Py2)
Length = 330
Score = 42.7 bits (96), Expect = 0.007
Identities = 38/160 (23%), Positives = 64/160 (40%), Gaps = 3/160 (1%)
Frame = +3
Query: 123 ALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTK--VIGATSLDDMVSK 296
A+IGL MG + ++ G+ V F+ + VE F +G A D +VS
Sbjct: 36 AVIGLGSMGYGMAQSLKRAGFDVAGFDVNAAAVERFAAEGGRGASSPAEAARDADVVVSV 95
Query: 297 LKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYV 476
+ + ++ F D + L + G + + + L TG LY+
Sbjct: 96 VVNAAQTETIL---FGADGVAQTL----ADGAVFLSSATMDPEIARTLAARLEATGRLYL 148
Query: 477 GMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAICAK 593
+SGG A G +++ G PAA+ + A+ AK
Sbjct: 149 DAPISGGAQRAAEGALTILASGSPAAFAKARPALDAMAAK 188
>UniRef50_Q9K9L1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Bacillus|Rep: 3-hydroxyisobutyrate dehydrogenase -
Bacillus halodurans
Length = 299
Score = 42.3 bits (95), Expect = 0.009
Identities = 38/155 (24%), Positives = 68/155 (43%), Gaps = 1/155 (0%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
+ +GL MG + ++ DKG+ +R+ +EE ++ A I S +++
Sbjct: 5 VGFVGLGTMGLPMTKHLVDKGFETYVKSRSRGPIEEAIQYGA-----IEVESYKELMETA 59
Query: 300 KRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVG 479
+ L + V E LI LS+G I+ID + +++ G ++
Sbjct: 60 DIVMTCLPLPETVIDVYEGEDGLIAGLSQGKILIDHSTVDRETNVRVAEQIKEKGGAFLD 119
Query: 480 MGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQA 581
VSGG GA+ G ++M GG ++ KE+ A
Sbjct: 120 APVSGGPMGAKAGTLTIMCGGEADSFERSKEVLGA 154
>UniRef50_Q5WBB8 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Bacillus clausii KSM-K16|Rep: 3-hydroxyisobutyrate
dehydrogenase - Bacillus clausii (strain KSM-K16)
Length = 283
Score = 42.3 bits (95), Expect = 0.009
Identities = 39/159 (24%), Positives = 70/159 (44%), Gaps = 4/159 (2%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
+ LIG MG+ + ++ GY V ++ +SK E L+ + GA +++ +
Sbjct: 4 VGLIGCGAMGKGMATSLLSAGYTVYIYD-DMSKWREPLEKQ-------GACFVENSAAVA 55
Query: 300 KRPRKIVL-LVKAGFAVDEFVKK--LIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGIL 470
K+ + ++L L D K ++ L G ++D + T K + GI
Sbjct: 56 KKAKYVLLSLPSPNIVADTVAGKEGVLCHLQTGGFLLDLSTTDVQTTLAMEKAAAAKGIY 115
Query: 471 YVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAI 584
Y+ VSGG GA G ++M GG A+ +K + +
Sbjct: 116 YLDCPVSGGPAGADAGTLTIMVGGDKQAYFSVKPLLDIL 154
>UniRef50_A5GPC0 Cluster: Hydroxyacid dehydrogenase/reductase family
protein; n=14; Cyanobacteria|Rep: Hydroxyacid
dehydrogenase/reductase family protein - Synechococcus
sp. (strain WH7803)
Length = 302
Score = 42.3 bits (95), Expect = 0.009
Identities = 34/159 (21%), Positives = 69/159 (43%), Gaps = 4/159 (2%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
+A +GL +G + N++ GY + R+ S + + +G +
Sbjct: 12 LAFVGLGALGLPIAANLHRAGYSLQVHTRSRSAEND--PSLHQGDPAAATLCCASPADAV 69
Query: 300 KRPRKIVLLVKAGFAVDEFV---KKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGIL 470
+ + +VL V AV+ + P L++G ++ID +Q+ + L+ G+
Sbjct: 70 QGCQALVLCVSDDAAVEAVLWGDNGAGPALAEGSLVIDCSTISPSTSQRMARRLAHRGVR 129
Query: 471 YVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAI 584
Y+ V+GG +GA+ G +++ GG A + + I
Sbjct: 130 YLDAPVTGGTEGAKAGTLTVLCGGSDADLDRAMPVLETI 168
>UniRef50_A5BFV6 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 304
Score = 42.3 bits (95), Expect = 0.009
Identities = 19/45 (42%), Positives = 28/45 (62%)
Frame = +3
Query: 468 LYVGMGVSGGEDGARYGPSLMPGGHPAAWPHIKEIFQAICAKAND 602
+Y+ G G E+GAR+GPSLMPGG +I++I A+ +D
Sbjct: 18 MYLDGGDDGDEEGARHGPSLMPGGSSKTHRYIEDILLERAAQVSD 62
>UniRef50_A6EH53 Cluster: Putative uncharacterized protein; n=1;
Pedobacter sp. BAL39|Rep: Putative uncharacterized
protein - Pedobacter sp. BAL39
Length = 292
Score = 41.9 bits (94), Expect = 0.012
Identities = 43/146 (29%), Positives = 65/146 (44%), Gaps = 4/146 (2%)
Frame = +3
Query: 129 IGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKLKRP 308
IGL MG + + +KGY + +NRT+SK E + A+G KV G ++++
Sbjct: 18 IGLGNMGVPMAGQVLNKGYSLTVYNRTLSKTEPLV---AQGAKVAGTPG--ELIAATD-- 70
Query: 309 RKIVLLVKAGFAVDEFVKKLIPLLSK---GDIIIDGGNSQYLDTQKWCKELSGTGILYVG 479
+ L+V AV + LLSK G +I++ + K S GI Y+
Sbjct: 71 -IVFLMVSDDHAVASLFEGADGLLSKELHGKVIVNMSTVSPAISIKMAAACSAVGIEYLD 129
Query: 480 MGVSGGEDGARYGP-SLMPGGHPAAW 554
VSG A G +M GG A+
Sbjct: 130 APVSGSVKQATDGQLVIMVGGEEQAF 155
>UniRef50_A0K0Z6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=2; Micrococcineae|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Arthrobacter sp. (strain FB24)
Length = 301
Score = 41.9 bits (94), Expect = 0.012
Identities = 45/157 (28%), Positives = 67/157 (42%), Gaps = 2/157 (1%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
IA+IGL MG + ++ G+ V F+ + E + A T + SLDD+
Sbjct: 7 IAVIGLGAMGGAMAATLHKAGWDVTGFDPS-----EAARTAAAQTGIATTASLDDVAGT- 60
Query: 300 KRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGT-GILYV 476
VL + A V+ V +L+ + G + I + T K L+ T G +V
Sbjct: 61 ---PYAVLSLPAASIVETTVPRLLAV--PGTVAIIDTTTSEPATSKQMAHLADTQGAAFV 115
Query: 477 GMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAI 584
VSGG DGA G S GG AA + + A+
Sbjct: 116 DAPVSGGRDGAASGSLSAFVGGTDAALAAAEPVLLAL 152
>UniRef50_UPI0000D56743 Cluster: PREDICTED: similar to
3-hydroxyisobutyrate dehydrogenase; n=1; Tribolium
castaneum|Rep: PREDICTED: similar to
3-hydroxyisobutyrate dehydrogenase - Tribolium castaneum
Length = 315
Score = 41.1 bits (92), Expect = 0.021
Identities = 40/149 (26%), Positives = 61/149 (40%), Gaps = 4/149 (2%)
Frame = +3
Query: 105 QNEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDD 284
+N +A IG+ MG + N+ KG V F+ T A V GA ++
Sbjct: 21 RNAGTLAFIGIGNMGSRMANNLVKKGETVRVFDLT----------PANAKSVPGAQVCNN 70
Query: 285 MVSKLKRPRKIVLLVKAGFAVDEFV---KKLIPLLSKGDIIIDGGNSQYLDTQKWCKELS 455
+K I+ ++ G V + V ++ SKG ++ID Q Q+ K
Sbjct: 71 QEEAVKDASVIITMLPNGDIVKDTVLGTNGILKHASKGSLLIDCSTIQPQVAQEVSKATY 130
Query: 456 GTGILYVGMGVSGGEDGARYGP-SLMPGG 539
G ++ VSGG GA G + M GG
Sbjct: 131 SAGFKFLDAPVSGGVTGAEAGTLTFMVGG 159
>UniRef50_Q183P5 Cluster: 2-hydroxy-3-oxopropionate reductase; n=5;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Clostridium difficile (strain 630)
Length = 296
Score = 41.1 bits (92), Expect = 0.021
Identities = 37/153 (24%), Positives = 66/153 (43%), Gaps = 1/153 (0%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
+ IGL +MG+ + N+ G + ++ S V+E + AK V+ D+V +
Sbjct: 3 LGFIGLGIMGKPMAKNLLKDGCNLLVYDINKSAVDELISCGAKYASVLEMGQECDIVFTI 62
Query: 300 KRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVG 479
IV + F +D K L +G I++D + ++ +L G+ ++
Sbjct: 63 LPNGTIVQDIL--FGMDGLAK----TLKEGSIVVDMSSVTPTESILCANKLKDMGLEFID 116
Query: 480 MGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIF 575
VSGGE A G + M GG + ++ F
Sbjct: 117 SPVSGGEPKAIDGTLAFMAGGKEEIYKKVEPFF 149
>UniRef50_Q12CU4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=17;
Proteobacteria|Rep: 2-hydroxy-3-oxopropionate reductase
- Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 298
Score = 41.1 bits (92), Expect = 0.021
Identities = 34/146 (23%), Positives = 62/146 (42%), Gaps = 3/146 (2%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
I +G MG + + + GY + +NRT ++ A +GAT + +
Sbjct: 12 ITFLGTGSMGLPMARRLCEAGYALQVWNRTPAR--------AASLAALGATIHEQARAAA 63
Query: 300 KRPRKIVLLVKAGFAVDE--FVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILY 473
+ +V +++ G V + F + + + G + +D + + + L GI +
Sbjct: 64 RDADIVVSMLENGAVVQDVLFAQGVAAAMKPGSLFLDMASITPREARDHAARLGALGIAH 123
Query: 474 VGMGVSGGEDGARYGP-SLMPGGHPA 548
+ VSGG GA G +M GG PA
Sbjct: 124 LDTPVSGGTVGAEQGTLVIMAGGKPA 149
>UniRef50_A6RYG0 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 159
Score = 41.1 bits (92), Expect = 0.021
Identities = 42/154 (27%), Positives = 68/154 (44%), Gaps = 5/154 (3%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYV---VCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMV 290
+A IG+ +MGQ + N+ +KG + +NRT S+ EE A+ I ++SL ++V
Sbjct: 5 LAFIGMGLMGQGITKNLVEKGEFEKPLILYNRTQSRAEE---QSARIGHSIVSSSLSEVV 61
Query: 291 SKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGIL 470
SK I ++ AV E K L +G + ++ K++ G
Sbjct: 62 SKAD---IIWSCIQNEEAVTEMFKSLSSFDIRGKLFVESSTIPAETADSLSKQILDAGAE 118
Query: 471 YVGMGVSGGEDGARYGPSL--MPGGHPAAWPHIK 566
+V M V GE Y +L +P G + IK
Sbjct: 119 FVSMPVF-GEPSLAYAGNLVCVPAGPRESVARIK 151
>UniRef50_O34948 Cluster: Uncharacterized oxidoreductase ykwC; n=19;
cellular organisms|Rep: Uncharacterized oxidoreductase
ykwC - Bacillus subtilis
Length = 288
Score = 41.1 bits (92), Expect = 0.021
Identities = 41/156 (26%), Positives = 67/156 (42%), Gaps = 4/156 (2%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
I IGL VMG+++ ++ + G+ V + RT K E L+ GA D +
Sbjct: 5 IGFIGLGVMGKSMASHILNDGHPVLVYTRTKEKAESILQK--------GAIWKDTVKDLS 56
Query: 300 KRPRKIVLLVKAGFAVDEFV---KKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGIL 470
K I+ +V V+E +I +G +ID S+ +K + +
Sbjct: 57 KEADVIITMVGYPSDVEEVYFGSNGIIENAKEGAYLIDMTTSKPSLAKKIAEAAKEKALF 116
Query: 471 YVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIF 575
+ VSGG+ GA+ G ++M GG A+ IF
Sbjct: 117 ALDAPVSGGDIGAQNGTLAIMVGGEKEAFEACMPIF 152
>UniRef50_Q0QLF5 Cluster: 2-hydroxymethyl glutarate dehydrogenase;
n=1; Eubacterium barkeri|Rep: 2-hydroxymethyl glutarate
dehydrogenase - Eubacterium barkeri (Clostridium
barkeri)
Length = 301
Score = 40.7 bits (91), Expect = 0.027
Identities = 42/159 (26%), Positives = 66/159 (41%), Gaps = 4/159 (2%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKG---TKVIGATSLDDMV 290
I IGL MG+ + +N+ +G V AF+ + V + A+ + + A S D++
Sbjct: 7 IGFIGLGAMGKPMAINLLKEGVTVYAFDLMEANVAAVVAQGAQACENNQKVAAAS--DII 64
Query: 291 SKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGIL 470
IV V G ++ G +I+D + T K K + GI
Sbjct: 65 FTSLPNAGIVETVMNGPG------GVLSACKAGTVIVDMSSVSPSSTLKMAKVAAEKGID 118
Query: 471 YVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAI 584
YV VSGG GA G ++M G A + I+ + I
Sbjct: 119 YVDAPVSGGTKGAEAGTLTIMVGASEAVFEKIQPVLSVI 157
>UniRef50_P31937 Cluster: 3-hydroxyisobutyrate dehydrogenase,
mitochondrial precursor; n=38; Eumetazoa|Rep:
3-hydroxyisobutyrate dehydrogenase, mitochondrial
precursor - Homo sapiens (Human)
Length = 336
Score = 40.7 bits (91), Expect = 0.027
Identities = 35/147 (23%), Positives = 68/147 (46%), Gaps = 3/147 (2%)
Frame = +3
Query: 108 NEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDM 287
++ + IGL MG + N+ GY + ++ +EF + G +V+ + + D+
Sbjct: 38 SKTPVGFIGLGNMGNPMAKNLMKHGYPLIIYDVFPDACKEF---QDAGEQVVSSPA--DV 92
Query: 288 VSKLKRPRKIVLLVKAGFAVDEF--VKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGT 461
K R I +L + A++ + ++ + KG ++ID +++ KE+
Sbjct: 93 AEKADRI--ITMLPTSINAIEAYSGANGILKKVKKGSLLIDSSTIDPAVSKELAKEVEKM 150
Query: 462 GILYVGMGVSGGEDGARYGP-SLMPGG 539
G +++ VSGG AR G + M GG
Sbjct: 151 GAVFMDAPVSGGVGAARSGNLTFMVGG 177
>UniRef50_Q98K09 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7;
Alphaproteobacteria|Rep: 3-hydroxyisobutyrate
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 312
Score = 40.3 bits (90), Expect = 0.036
Identities = 40/157 (25%), Positives = 65/157 (41%), Gaps = 4/157 (2%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSK-VEEFLKNEAK--GTKVIGATSLDDMV 290
I IGL +MG + N+ DKGY + R K E+ L A+ T A + D +
Sbjct: 10 IGFIGLGLMGHGIAKNIVDKGYPLTFLGRKNRKPAEDLLGRGAREASTSRDVAVASDIVF 69
Query: 291 SKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGIL 470
+ R++ +++ + E +K KG +++D S + T EL GI
Sbjct: 70 ICVTGSREVEAIIRGPGGLKEGLK-------KGSVVVDCSTSDPVSTVALAAELKALGID 122
Query: 471 YVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQ 578
YV +S A G M G A + +K + +
Sbjct: 123 YVDAPLSRTPKEAWEGTLDAMVGAPDAVFARVKPVIE 159
>UniRef50_Q830A7 Cluster: 2-hydroxy-3-oxopropionate reductase; n=7;
Firmicutes|Rep: 2-hydroxy-3-oxopropionate reductase -
Enterococcus faecalis (Streptococcus faecalis)
Length = 296
Score = 40.3 bits (90), Expect = 0.036
Identities = 41/156 (26%), Positives = 69/156 (44%), Gaps = 3/156 (1%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEA--KGTKVIGATSLDDMVS 293
I IG VMG+++I NM V +NRT SK ++ + A T A + D + +
Sbjct: 4 IGFIGTGVMGKSIIRNMMKNNLSVNVYNRTKSKTDDLVAEGAVWYDTPKAIAEASDIIFT 63
Query: 294 KLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILY 473
+ P + G +E + G I++D S +K K+ + G
Sbjct: 64 MVGFPSDV-----EGVYFNE--TGIFQADLTGKIVVDLTTSTPTLAEKIAKKAAEVGAHA 116
Query: 474 VGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQ 578
+ VSGG+ GA+ G ++M GG ++ + IF+
Sbjct: 117 LDAPVSGGDLGAKNGTLTIMVGGDQESYDTVLPIFK 152
>UniRef50_A7PEG7 Cluster: Chromosome chr11 scaffold_13, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr11 scaffold_13, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 348
Score = 40.3 bits (90), Expect = 0.036
Identities = 40/157 (25%), Positives = 67/157 (42%), Gaps = 5/157 (3%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEA-KGTKVIGATSLDDMV-S 293
+ IG VMG+++ ++ GY V FNRT+SK + L A + + S D+V S
Sbjct: 51 VGWIGTGVMGRSMCAHLMKAGYTVTIFNRTISKAQPLLDMGAHHASSPLALASQSDVVFS 110
Query: 294 KLKRPRKI--VLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGI 467
+ P + VLL + A+ L G +++D S + + G
Sbjct: 111 IVGFPSDVRSVLLDPSSGALSG--------LRPGGVLVDMTTSDPSLAAEIASSAASRGC 162
Query: 468 LYVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIF 575
V VSGG+ GA+ ++ GG + + +F
Sbjct: 163 FSVDAPVSGGDRGAKNATLAIFAGGDESVVRRLNPLF 199
>UniRef50_Q0U6Q6 Cluster: Putative uncharacterized protein; n=5;
Pezizomycotina|Rep: Putative uncharacterized protein -
Phaeosphaeria nodorum (Septoria nodorum)
Length = 311
Score = 40.3 bits (90), Expect = 0.036
Identities = 39/167 (23%), Positives = 75/167 (44%), Gaps = 5/167 (2%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYV---VCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMV 290
+A +GL MG+ + N+ +KG + + +NRT + ++ L ++ G T + D +
Sbjct: 5 LAWLGLGNMGRGMCKNLVEKGNLDKPLIIYNRTKKRSDD-LSDKIASDVGSGKTKVVDTI 63
Query: 291 SKLKRPRKIVLLVKAG-FAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGI 467
+ + I+ + AV+ V ++ +KG +I+D T K ++ G
Sbjct: 64 NAATKEADIIFMCLGDDAAVNSTVDTILQEDTKGKLIVDCSTVHPDTTNALEKRITEKGA 123
Query: 468 LYVGMGVSGGEDGARYGPSL-MPGGHPAAWPHIKEIFQAICAKANDE 605
+VGM V G A G + + G AA +K + + +A+ E
Sbjct: 124 EFVGMPVFGAPAMADNGQLVCVIAGTKAAVAKVKPYTKGVMGRADIE 170
>UniRef50_A7DSF1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
2-hydroxy-3-oxopropionate reductase - Candidatus
Nitrosopumilus maritimus SCM1
Length = 292
Score = 40.3 bits (90), Expect = 0.036
Identities = 39/162 (24%), Positives = 77/162 (47%), Gaps = 4/162 (2%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
I ++GL ++G + L++ + G+ V FNR+ K++ K GAT +D
Sbjct: 4 IGIVGLGMLGNAVGLHLLESGFEVTVFNRS--------KDKTIQAKEKGATVVDSPKEVA 55
Query: 300 KRPRKIVLLVKAGFAVDE--FVKK-LIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGIL 470
++ ++++VK AV E F ++ +I +K I+ D +++ + GI
Sbjct: 56 EKSDLVIIVVKDADAVKEVSFEREGIIKSENKKLIVADMSTIDPSESKNISDKFLEFGIH 115
Query: 471 YVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAICAK 593
+ + V GG + A G +M G+ ++ K++F+ I K
Sbjct: 116 KLDIPVMGGPNVAITGDLVMMASGNKESFEECKKVFEKIANK 157
>UniRef50_Q55702 Cluster: Uncharacterized oxidoreductase slr0229;
n=4; Cyanobacteria|Rep: Uncharacterized oxidoreductase
slr0229 - Synechocystis sp. (strain PCC 6803)
Length = 290
Score = 40.3 bits (90), Expect = 0.036
Identities = 39/167 (23%), Positives = 73/167 (43%), Gaps = 5/167 (2%)
Frame = +3
Query: 108 NEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSK--VEEFLKNEAK--GTKVIGATS 275
N + IA+ GL VMG + N+ GY +NRT+ + V+E K K + + A +
Sbjct: 2 NVSKIAVFGLGVMGSPMAQNLVKNGYQTVGYNRTLERPSVQEAAKAGVKVVTSIAVAAAN 61
Query: 276 LDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELS 455
D +++ + + + L+ + E+ K +IID + L
Sbjct: 62 ADIILTCVGDEKDVQQLILGSGGIAEYAKPQA-------LIIDCSTIGKTAAYELATNLK 114
Query: 456 GTGILYVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAICAK 593
G+ ++ V+GG+ GA G ++M GG + + + ++I K
Sbjct: 115 LQGLRFLDAPVTGGDVGAINGTLTIMVGGDISDFEEALPVLKSIGEK 161
>UniRef50_Q0BTJ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Granulibacter bethesdensis CGDNIH1|Rep:
2-hydroxy-3-oxopropionate reductase - Granulobacter
bethesdensis (strain ATCC BAA-1260 / CGDNIH1)
Length = 293
Score = 39.9 bits (89), Expect = 0.048
Identities = 41/157 (26%), Positives = 70/157 (44%), Gaps = 2/157 (1%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
IA++G +MG+ + + D G+ V +NR + E G V ATS D
Sbjct: 9 IAVLGTGIMGRWMACRLADAGHEVTVWNRNPVRAAEL------GLPV--ATSAPDAAHGA 60
Query: 300 KRPRKIVLLVKAGFAVDEFVKK-LIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYV 476
+L+V G A D ++ + +++ ++ + + + K++S YV
Sbjct: 61 D---VALLMVSDGPACDAVLETGFVDTMAQNGTVLVMSSIEPWRARAQAKKVSPR--FYV 115
Query: 477 GMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAI 584
VSGGE GAR G ++M GG A + +F A+
Sbjct: 116 DAPVSGGEGGARNGTLAIMAGGEEAVLNRLAPVFAAL 152
>UniRef50_A5FVG0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=1; Acidiphilium cryptum
JF-5|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
precursor - Acidiphilium cryptum (strain JF-5)
Length = 292
Score = 39.9 bits (89), Expect = 0.048
Identities = 40/157 (25%), Positives = 64/157 (40%), Gaps = 1/157 (0%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
I +IGL MG + + ++G+ VC +NRT ++ E AK + A S D ++ L
Sbjct: 5 IGVIGLGRMGAAMAARLIERGHQVCGWNRTAARAEAIQGLAAKASPAEVAMSADYVIVML 64
Query: 300 KRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVG 479
L A A L+ + ++ID + D Q + ++ G +V
Sbjct: 65 -------LDETASRAAYHGEGGLLSANLQQALVIDMSTLKPADMQANAEAVTAHGGRFVA 117
Query: 480 MGVSGGEDGARYGPSL-MPGGHPAAWPHIKEIFQAIC 587
V G AR G L + GG A K + +C
Sbjct: 118 CPVGGTVGPARSGKLLGLAGGDAATIDAAKPVLDELC 154
>UniRef50_A4FKN9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
2-hydroxy-3-oxopropionate reductase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 297
Score = 39.9 bits (89), Expect = 0.048
Identities = 42/162 (25%), Positives = 70/162 (43%), Gaps = 4/162 (2%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
+ +IGL MG NL L + + G V A +R+ E + +G +V+ +
Sbjct: 5 VGVIGLGPMGANLALRLAEAGLDVVATSRSQGTREAAAR---EGVRVVDDVRALAGRLRA 61
Query: 300 KRPRKIVLL-VKAGFAVDEFVKKLIPLLSKGD--IIIDGGNSQYLDTQKWCKELSGTGIL 470
P+ +V++ + +G V V + LL+ G +++D D + +L G
Sbjct: 62 ASPKPVVVVSLPSGPQVRAAV--VDGLLADGGEFVVVDTSTCAPADARSLADDLHARGCA 119
Query: 471 YVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAICAK 593
V VSGG AR G S+M GG A E+ +A +
Sbjct: 120 VVDAPVSGGPTAARAGSLSVMVGGTEADVAAADEVIRAFAGR 161
>UniRef50_A0G5G5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia phymatum
STM815
Length = 306
Score = 39.9 bits (89), Expect = 0.048
Identities = 39/163 (23%), Positives = 65/163 (39%), Gaps = 1/163 (0%)
Frame = +3
Query: 108 NEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDM 287
N+ I IGL MG + + D G V ++ +V+ A + + D+
Sbjct: 2 NKERIGFIGLGNMGGRMTRRLVDAGISVLGYDTAPERVKAAGAQAA--SSIADVMKFADV 59
Query: 288 VSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGI 467
V K+V V G ++ I++D + T + + + +G+
Sbjct: 60 VMMSLPDSKVVEAVVEGDG------GVLAHCRARQIVVDLSTAAASSTIRLARRFTQSGV 113
Query: 468 LYVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAICAK 593
YV G+SGG A G +LM GG +A +K F I +K
Sbjct: 114 QYVDAGISGGAAAAEKGALTLMVGGDASAVDALKWAFAPISSK 156
>UniRef50_Q7NWA9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Chromobacterium violaceum
Length = 296
Score = 39.5 bits (88), Expect = 0.063
Identities = 39/159 (24%), Positives = 68/159 (42%), Gaps = 3/159 (1%)
Frame = +3
Query: 117 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLK--NEAKGTKVIGATSLDDMV 290
+IA IGL MG + +N+ +KG+ V AF+ + + + A + A S ++
Sbjct: 3 NIAFIGLGNMGGPMAVNLLNKGFKVSAFDLSADALAKVAAAGGRAASSAADAAESASVVI 62
Query: 291 SKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGIL 470
S L + + AG + + L L KG ++ID +K + G+
Sbjct: 63 SMLPAGKHV-----AGLYLGD--NGLFARLPKGALVIDCSTIDAGTARKVAEGAREKGLS 115
Query: 471 YVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAI 584
+ VSGG GA G + + GG H + + +A+
Sbjct: 116 MLDAPVSGGTAGAAAGTLTFIVGGAAEDLAHARPVLEAM 154
>UniRef50_Q01ZG6 Cluster: 2-hydroxy-3-oxopropionate reductase; n=6;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Solibacter usitatus (strain Ellin6076)
Length = 298
Score = 39.5 bits (88), Expect = 0.063
Identities = 37/156 (23%), Positives = 67/156 (42%), Gaps = 3/156 (1%)
Frame = +3
Query: 114 ADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDD--M 287
ADI IGL +MG+ + N+ GY + ++ V E + A AT+ +
Sbjct: 2 ADIGFIGLGIMGKPMSRNLMKAGYSLVVYDIFPGPVAELKEAGAGAGASCAATAAAAPIV 61
Query: 288 VSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGI 467
++ L ++ V V E K G +++D + + +QK + G+
Sbjct: 62 ITMLPDGPEVETAVLGPGGVLEGAKA-------GTVVVDMSSISPMVSQKVAAACAAKGV 114
Query: 468 LYVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEI 572
++ VSGGE A G ++M GG P + ++ +
Sbjct: 115 EFLDAPVSGGEPKAIDGTLAIMVGGKPEVFERVQPV 150
>UniRef50_A7JGH8 Cluster: Predicted protein; n=1; Francisella
tularensis subsp. novicida GA99-3549|Rep: Predicted
protein - Francisella tularensis subsp. novicida
GA99-3549
Length = 293
Score = 39.5 bits (88), Expect = 0.063
Identities = 37/162 (22%), Positives = 66/162 (40%), Gaps = 3/162 (1%)
Frame = +3
Query: 117 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVI--GATSLDDMV 290
+IA IGL MG ++ N+ D GY V F+ ++ ++ + N K I D ++
Sbjct: 3 NIAFIGLGCMGLHMAKNLIDNGYKVYGFDMSLDQLNKHQNNGGIAAKSIKEACGYADAII 62
Query: 291 SKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGIL 470
L P ++ + + + + + G IIID + K+ +
Sbjct: 63 LSLPGPNQVSNVCDSSDGI-------LKIAKAGTIIIDTSTIDANTSVLLAKKAKQNNLH 115
Query: 471 YVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAICAK 593
+ VSGG GA+ + M GG + K +F ++ K
Sbjct: 116 MLDAPVSGGIIGAQNATLTFMVGGDKEIFERCKNLFNSMGKK 157
>UniRef50_A3I4V2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Bacillus sp. B14905|Rep: 3-hydroxyisobutyrate
dehydrogenase - Bacillus sp. B14905
Length = 316
Score = 39.5 bits (88), Expect = 0.063
Identities = 40/153 (26%), Positives = 61/153 (39%), Gaps = 1/153 (0%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
+ IGL MG + +N+ Y V F+ VE F EA G + A + +
Sbjct: 24 LGFIGLGNMGLPMSINLLKANYEVYGFDTNAKAVELF--TEAGGIGLASAKDVAKQCDVV 81
Query: 300 KRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVG 479
+V+ + +E + I KG +++D KE S G+ Y+G
Sbjct: 82 MTSLPTPQIVEMVYLSEEGI---IHHAKKGALLVDFSTVNPDLNDSLHKEASTLGLRYLG 138
Query: 480 MGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIF 575
VSGG GA ++M GG + EIF
Sbjct: 139 APVSGGVIGAVNATLTIMVGGGKDDYDSASEIF 171
>UniRef50_Q1QWU9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Chromohalobacter salexigens DSM 3043|Rep:
3-hydroxyisobutyrate dehydrogenase - Chromohalobacter
salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB13768)
Length = 310
Score = 39.1 bits (87), Expect = 0.084
Identities = 40/169 (23%), Positives = 75/169 (44%), Gaps = 4/169 (2%)
Frame = +3
Query: 99 MPQNEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSL 278
M ++ +I +IGL MG N+ + ++ G+ V T + V + ++ + + T L
Sbjct: 6 MNTDDMNIVVIGLGQMGGNMAMTLHAAGFTV-----TGTDVADAARDNL-AARGLSVTRL 59
Query: 279 DDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLS---KGDIIIDGGNSQYLDTQKWCKE 449
D L +L + V E ++ LL KG +I+D S T++ +
Sbjct: 60 D----ALPEADVYLLSLPTSAHVREVIETSPGLLQRAPKGSVIVDTSTSDPAVTRELAGK 115
Query: 450 LSGTGILYVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAICAK 593
+ G+ ++ VSGG GA G ++ GG A + + +A+ A+
Sbjct: 116 VVEAGLEWLDAPVSGGPAGAASGALGMLLGGESATIERLAPMLEAMSAR 164
>UniRef50_A6LNV2 Cluster: Ribonuclease, Rne/Rng family; n=1;
Thermosipho melanesiensis BI429|Rep: Ribonuclease,
Rne/Rng family - Thermosipho melanesiensis BI429
Length = 465
Score = 39.1 bits (87), Expect = 0.084
Identities = 27/102 (26%), Positives = 50/102 (49%), Gaps = 2/102 (1%)
Frame = +3
Query: 201 NRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLL 380
++ ++K+ E K + K + +L D + + K + + L++ F E ++K + +
Sbjct: 178 SKKINKIIESFKRKRKAQVLYKEENLLDYILREKLTKDVKLIITNNFKHVELIRKYLKIF 237
Query: 381 SKGDII--IDGGNSQYLDTQKWCKELSGTGILYVGMGVSGGE 500
SK I IDG + Y+D K+ +EL +L SGGE
Sbjct: 238 SKRPKIEIIDGDSFDYMDIYKYFRELLKRKVLL----PSGGE 275
>UniRef50_Q1N6I0 Cluster: Putative oxidoreductase protein; n=1;
Oceanobacter sp. RED65|Rep: Putative oxidoreductase
protein - Oceanobacter sp. RED65
Length = 289
Score = 38.7 bits (86), Expect = 0.11
Identities = 46/159 (28%), Positives = 69/159 (43%), Gaps = 4/159 (2%)
Frame = +3
Query: 117 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSK 296
+I+ IGL MG + ++ + + FNR+ SK E+F +N + T A SL D
Sbjct: 2 NISFIGLGKMGYPMAKHLVQANHQLEVFNRSPSKSEDFKRNFEQCTI---ANSLTDCG-- 56
Query: 297 LKRPRKIVLLVKAGFAVDEFV---KKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGI 467
K I+L + V + L L G ++ID + + +L +
Sbjct: 57 -KHSEIIILCIGNDEDVRNTLTGKDSLYSNLKPGTLVIDHTTTSAELACEMQAKLLEKQV 115
Query: 468 LYVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQA 581
YV VSGGE GA G ++M GG A + I QA
Sbjct: 116 DYVDAPVSGGEQGAISGQLTIMCGGQALAAERAQGITQA 154
>UniRef50_A3WAC4 Cluster: Dehydrogenase; n=4; Bacteria|Rep:
Dehydrogenase - Erythrobacter sp. NAP1
Length = 301
Score = 38.3 bits (85), Expect = 0.15
Identities = 38/162 (23%), Positives = 70/162 (43%), Gaps = 4/162 (2%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
IA +GL VMG + ++ G+ +NR +K EE+ ++ G + + A D + +
Sbjct: 7 IAFLGLGVMGGPMWGHLVRAGHEATGYNRNFAKAEEW--SDRLGDEGLVAPIESDAATAV 64
Query: 300 KRPRKIVLLVKAGFAVDEFV---KKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGIL 470
+ ++ + V + ++ + +G ID + ++ E G+
Sbjct: 65 RGKDVVLACLGNDDDVASVLFGENGVLAAMKRGATFIDHTSVSPGLARRIADECERLGLH 124
Query: 471 YVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAICAK 593
V VSGG+ GA G S+M GG A + + QA A+
Sbjct: 125 AVDAPVSGGQAGAENGKLSIMCGGSEEAMASAQPVMQAYAAR 166
>UniRef50_A3H5R1 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Caldivirga maquilingensis IC-167|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Caldivirga maquilingensis IC-167
Length = 295
Score = 38.3 bits (85), Expect = 0.15
Identities = 16/38 (42%), Positives = 24/38 (63%)
Frame = +3
Query: 117 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEF 230
++ LIGL MG + N+ D G ++ FNRT+SK +F
Sbjct: 3 NVGLIGLGTMGWRIAKNLKDDGLLIGVFNRTMSKAIKF 40
>UniRef50_Q39KK8 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=34; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia sp. (strain
383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
/ R18194))
Length = 289
Score = 37.9 bits (84), Expect = 0.19
Identities = 39/160 (24%), Positives = 61/160 (38%), Gaps = 1/160 (0%)
Frame = +3
Query: 117 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSK 296
D+ IGL MGQ + N+ G+ V +NR+ + A+ IGA +D
Sbjct: 2 DLGFIGLGEMGQAIATNLLKAGHTVRVWNRS--------RERAEPLAAIGAQIVDTPADA 53
Query: 297 LKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYV 476
+ +L A F L+ +G I ++ + + GI YV
Sbjct: 54 FRGDAVFSMLADDAAARAIFDDALLAQAPRGLIHVNMATVSVALAESLAHAHASRGIHYV 113
Query: 477 GMGVSGGED-GARYGPSLMPGGHPAAWPHIKEIFQAICAK 593
V G D A ++M GG A ++ +F AI K
Sbjct: 114 AAPVMGRPDVAAAARLTIMAGGPAEAIDRVQPLFDAIGQK 153
>UniRef50_A1SIN3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Nocardioides sp. JS614|Rep: 3-hydroxyisobutyrate
dehydrogenase - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 308
Score = 37.9 bits (84), Expect = 0.19
Identities = 39/152 (25%), Positives = 63/152 (41%), Gaps = 6/152 (3%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAK-GTKVIGATSLDDMVSK 296
IA IGL MG ++ N+ G+ V F+ + + V+ A + D+V
Sbjct: 4 IAFIGLGNMGNSMAKNLIAAGFDVVGFDADSRTNQRSAETGIPVAADVVDAVTGADVVIT 63
Query: 297 LKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYV 476
+ I+ V G + V + L+ G ++ID + + + + GI ++
Sbjct: 64 MLPNGDILRQVLLGAGAESGV---LNYLAPGALVIDSSSIDVANCLAVHESAASAGIAFL 120
Query: 477 GMGVSGGEDGARYGP-SLMPGGHPA----AWP 557
VSGG GA G + M GG A AWP
Sbjct: 121 DAPVSGGVGGAAAGTLTFMVGGDEAHVRRAWP 152
>UniRef50_Q94B07 Cluster: Gamma hydroxybutyrate dehydrogenase; n=16;
cellular organisms|Rep: Gamma hydroxybutyrate
dehydrogenase - Arabidopsis thaliana (Mouse-ear cress)
Length = 289
Score = 37.9 bits (84), Expect = 0.19
Identities = 14/43 (32%), Positives = 29/43 (67%)
Frame = +3
Query: 117 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEA 245
++ +GL +MG+ + +N+ G+ V +NRT+SK +E +++ A
Sbjct: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGA 44
>UniRef50_Q4Q7T9 Cluster: 2-hydroxy-3-oxopropionate reductase,
putative; n=6; Trypanosomatidae|Rep:
2-hydroxy-3-oxopropionate reductase, putative -
Leishmania major
Length = 299
Score = 37.9 bits (84), Expect = 0.19
Identities = 40/162 (24%), Positives = 71/162 (43%), Gaps = 4/162 (2%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAK--GTKVIGATSLDDMVS 293
+ IGL +MG+ + +N+ G+ V +NRT SK ++ + A T A + D + +
Sbjct: 3 VGYIGLGLMGKPMAVNILKAGFPVSVWNRTASKCDDLVAAGATACATPAELAAASDVVFT 62
Query: 294 KLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL-SGTGIL 470
L ++ +V V + +G I +D + Q+ + L +
Sbjct: 63 NLSDSPDVMEVVFGPNGVAAGI-------CEGAIFVDNSTIKPSVAQEIARRLWKEKKVR 115
Query: 471 YVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAICAK 593
+ VSGG+ GAR G ++M GG AA + + A+ K
Sbjct: 116 ALDAPVSGGDIGARNGTLTVMVGGDAAALATVLPVLLAVGKK 157
>UniRef50_Q6F842 Cluster: Putative 3-hydroxyisobutyrate
dehydrogenase or 2-hydroxy-3- oxopropionate reductase;
n=2; Acinetobacter|Rep: Putative 3-hydroxyisobutyrate
dehydrogenase or 2-hydroxy-3- oxopropionate reductase -
Acinetobacter sp. (strain ADP1)
Length = 291
Score = 37.5 bits (83), Expect = 0.26
Identities = 33/140 (23%), Positives = 60/140 (42%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
IA IG+ +MG + + G+ V +NRT S + L +GA +L + K+
Sbjct: 9 IAFIGMGLMGSRMATRLVQAGFSVAVWNRTQSACDVLLD--------MGAQALS--LEKI 58
Query: 300 KRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVG 479
I++ + AV+ +++ L+ II+D + T+ +++
Sbjct: 59 ADYPVILMCLADDQAVNHVYEQVHHLVRPQQIIVDFSSLSVNQTKYLADRAQQQQAIWID 118
Query: 480 MGVSGGEDGARYGPSLMPGG 539
VSGG GA G ++ G
Sbjct: 119 SPVSGGTSGAEQGTLVIFAG 138
>UniRef50_Q2JEV5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=6; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Frankia sp. (strain CcI3)
Length = 302
Score = 37.5 bits (83), Expect = 0.26
Identities = 39/158 (24%), Positives = 65/158 (41%), Gaps = 4/158 (2%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
+A +GL MG + ++ G+ AFNRT + + + + A + ++
Sbjct: 3 VAFVGLGTMGFPMAGHLVRAGFSTTAFNRTAATAARWAEEHSGRIAPSPAAAATEV---- 58
Query: 300 KRPRKIVLLVKAGFAVDEFV---KKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGIL 470
+ L V A V E V ++ L G II+D + ++ + G+
Sbjct: 59 ---DVVCLCVGADDDVREVVLGADGVLGALRPGAIIVDHTTTSAELAEEIAARTAEVGVG 115
Query: 471 YVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQA 581
+V VSGGE GA G S+M GG P + + A
Sbjct: 116 FVDAPVSGGEAGAMAGRLSIMCGGDPETIERARPVLAA 153
>UniRef50_A0UF54 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia multivorans ATCC
17616|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
- Burkholderia multivorans ATCC 17616
Length = 289
Score = 37.5 bits (83), Expect = 0.26
Identities = 36/161 (22%), Positives = 66/161 (40%), Gaps = 3/161 (1%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIG--ATSLDDMVS 293
+ +IGL MG+ + ++ G+ V F+ V + + + A+++D ++
Sbjct: 4 VGVIGLGNMGRGIASSLKRAGFDVLGFDANAESVRQLADEGVRPCASVAEIASAVDVLIL 63
Query: 294 KLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILY 473
L + +V V K+ G I+ID + T+K L GI +
Sbjct: 64 SLPTSAIVEAVVLGDGGVASHAKR-------GLIVIDTTTADPNSTRKVAAALDAHGIGF 116
Query: 474 VGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAICAK 593
+ VSGG GA +++ GG ++ + AI AK
Sbjct: 117 IDGPVSGGPKGAATATMTMVLGGADEHIAAVQPVLSAISAK 157
>UniRef50_UPI00015B4B33 Cluster: PREDICTED: similar to
3-hydroxyisobutyrate dehydrogenase; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to
3-hydroxyisobutyrate dehydrogenase - Nasonia vitripennis
Length = 512
Score = 37.1 bits (82), Expect = 0.34
Identities = 16/52 (30%), Positives = 28/52 (53%)
Frame = +3
Query: 93 KKMPQNEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAK 248
K + + +GL +MG ++ N+ + G+ V +NRT K +FLK A+
Sbjct: 220 KNIRASSLKFGFLGLGIMGSGIVKNLLNSGHKVVVWNRTQEKCADFLKAGAE 271
>UniRef50_Q13LQ9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=11;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Burkholderia xenovorans (strain LB400)
Length = 296
Score = 37.1 bits (82), Expect = 0.34
Identities = 35/157 (22%), Positives = 67/157 (42%), Gaps = 2/157 (1%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGT-KVIGATSLDDMVSK 296
+ IGL +MG ++ + G+ + + ++ + + A SLD +++
Sbjct: 7 VGFIGLGMMGAPMVQCLRKAGFELFIDDADAARADTLAEQSGSHRLNADNAGSLDALITM 66
Query: 297 LKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYV 476
L P + V+A D L+KG ++ID +S+ ++ K L + Y+
Sbjct: 67 L--PNSAI--VEAVVLGDGNNTGWAARLAKGAVVIDMSSSEPERSRALGKTLEAQRLAYL 122
Query: 477 GMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAI 584
VSGG A+ G +++ GGH K + A+
Sbjct: 123 DAPVSGGVKRAKEGTLAILVGGHADVLARCKPLLDAM 159
>UniRef50_Q0SBQ9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=12;
Actinomycetales|Rep: 2-hydroxy-3-oxopropionate reductase
- Rhodococcus sp. (strain RHA1)
Length = 294
Score = 37.1 bits (82), Expect = 0.34
Identities = 42/159 (26%), Positives = 67/159 (42%), Gaps = 4/159 (2%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGT---KVIGATSLDDMV 290
IA IGL +MG + N+ G+ V +N + + EA GT + A + D+V
Sbjct: 4 IAFIGLGIMGSPMACNLAKAGHQVVGYNLIPDRTAALV--EAGGTAADSIAKAVAGADVV 61
Query: 291 SKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGIL 470
+ + V V G ++ V + P G +IID + + T + + G
Sbjct: 62 AVMVPDSPDVQAVLTG---EDGVFEHTP---SGALIIDFSSIRPDVTTALAAQATERGFR 115
Query: 471 YVGMGVSGGEDGA-RYGPSLMPGGHPAAWPHIKEIFQAI 584
+ VSGGE GA S+M GG P + + I +
Sbjct: 116 LIDAPVSGGEAGAVNAALSIMVGGAPEDFESARPILDVV 154
>UniRef50_Q4ZQL5 Cluster: 3-hydroxyisobutyrate dehydrogenase
precursor; n=11; Proteobacteria|Rep:
3-hydroxyisobutyrate dehydrogenase precursor -
Pseudomonas syringae pv. syringae (strain B728a)
Length = 296
Score = 36.7 bits (81), Expect = 0.45
Identities = 37/140 (26%), Positives = 62/140 (44%), Gaps = 5/140 (3%)
Frame = +3
Query: 126 LIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTK-VIGATSL----DDMV 290
+IGL MG + + KG+ V F+ + + + + E+KG K V T L D ++
Sbjct: 7 VIGLGNMGGGMAATLAGKGFDVSGFDLSQAALAQA---ESKGVKPVADRTQLIQGVDILI 63
Query: 291 SKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGIL 470
L + + + ++E +K G I++D S ++K EL+ GI
Sbjct: 64 LSLPKAEHVESVCLGAGGINEVGRK-------GLIVVDTTTSTPEMSRKVAAELAKNGIA 116
Query: 471 YVGMGVSGGEDGARYGPSLM 530
++ VSGG GA G M
Sbjct: 117 FIDAPVSGGPKGAATGSMSM 136
>UniRef50_Q1INE9 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Acidobacteria bacterium Ellin345|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Acidobacteria bacterium (strain Ellin345)
Length = 313
Score = 36.3 bits (80), Expect = 0.59
Identities = 36/157 (22%), Positives = 67/157 (42%), Gaps = 2/157 (1%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
+ +GL MG+ + N+ G+ V +NRT +K E + +G KV AT + D V
Sbjct: 25 VGFLGLGNMGEPMAANLIAAGHQVTVWNRTAAKAEPL---KERGVKV--ATEIKDAV--- 76
Query: 300 KRPRKIVLLVKAGFAVDEFVK-KLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYV 476
+ + +V A+ ++ L+ L KG + + ++ +E G ++
Sbjct: 77 QNQDVVCTMVADDHALRTILEGGLLEALPKGAVHVSHSTVSVAMAEELKREHGKRGQAFI 136
Query: 477 GMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAI 584
V G + A+ ++ G PA +K + AI
Sbjct: 137 SAPVFGRPEAAQAKKLFVVVSGDPAVIEKVKPVLDAI 173
>UniRef50_A7H7Z5 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding; n=2; Anaeromyxobacter|Rep:
6-phosphogluconate dehydrogenase NAD-binding -
Anaeromyxobacter sp. Fw109-5
Length = 293
Score = 36.3 bits (80), Expect = 0.59
Identities = 33/143 (23%), Positives = 58/143 (40%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
I +GL +G+ + N+ G+ + +NRT SK + +KG K+ G S + +
Sbjct: 5 IGFVGLGTIGEPIANNLRKAGHDLTVWNRTPSKAAHIV---SKGGKLAG--SARECATGR 59
Query: 300 KRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVG 479
V KA V E ++ L GD+++D + + + + G +V
Sbjct: 60 DLVITCVSDEKALDTVLEGPDGVLEALRDGDVLVDMSTAGVRAARSVSERAAARGAGFVA 119
Query: 480 MGVSGGEDGARYGPSLMPGGHPA 548
V G A ++ G PA
Sbjct: 120 CPVLGSRSAAEQAQLVLVAGGPA 142
>UniRef50_A6VLT0 Cluster: 2-hydroxy-3-oxopropionate reductase; n=2;
Pasteurellaceae|Rep: 2-hydroxy-3-oxopropionate reductase
- Actinobacillus succinogenes 130Z
Length = 289
Score = 36.3 bits (80), Expect = 0.59
Identities = 35/160 (21%), Positives = 67/160 (41%), Gaps = 2/160 (1%)
Frame = +3
Query: 108 NEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDM 287
N ++ IGL MG+ + ++ + G V +NRT K + AKG V +
Sbjct: 5 NTREVGWIGLGQMGEPMAAHLLEHGVKVGVYNRTAEKCQNV---AAKGASVYSS------ 55
Query: 288 VSKLKRPRKIVLLVKAGF-AVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTG 464
V +L + ++ ++ A F ++ + + + KG ++++ Q+ L+ G
Sbjct: 56 VLELVKAYDVIFVMVADFPVIESLLSEEVLTALKGKLVVNMSTVSPTQNQQLEFLLAKHG 115
Query: 465 ILYVGMGVSGGEDGARYGPSL-MPGGHPAAWPHIKEIFQA 581
++ VSG A G L + G +K +F A
Sbjct: 116 AEFIEAPVSGSSKVAEAGKLLVLAAGKEEIVEQLKPLFAA 155
>UniRef50_A4ECY9 Cluster: Putative uncharacterized protein; n=1;
Collinsella aerofaciens ATCC 25986|Rep: Putative
uncharacterized protein - Collinsella aerofaciens ATCC
25986
Length = 359
Score = 36.3 bits (80), Expect = 0.59
Identities = 35/139 (25%), Positives = 57/139 (41%), Gaps = 2/139 (1%)
Frame = +3
Query: 108 NEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEA--KGTKVIGATSLD 281
N+ +A IG +MG + ++ D GY V NRT SK ++ A T + D
Sbjct: 3 NKLSVAFIGTGIMGAPIAGHILDAGYPVTVNNRTKSKAAALIERGAVWAETPADAVVNAD 62
Query: 282 DMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGT 461
+ + + P ++ L AG L+ G ++ID S + + +
Sbjct: 63 VVFTMVGYPSEVEELYLAG-------DGLLTCTKPGAVLIDLTTSSPELARDIAEAAQVS 115
Query: 462 GILYVGMGVSGGEDGARYG 518
G + V+GGE GA G
Sbjct: 116 GRMAFDCPVTGGESGAIAG 134
>UniRef50_A6GTB5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein; n=1; Limnobacter sp. MED105|Rep:
6-phosphogluconate dehydrogenase, NAD-binding protein -
Limnobacter sp. MED105
Length = 299
Score = 35.9 bits (79), Expect = 0.78
Identities = 40/167 (23%), Positives = 65/167 (38%), Gaps = 4/167 (2%)
Frame = +3
Query: 90 LKKMPQNEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGA 269
+ P I IGL MG + ++ GY V A+ R S E ++
Sbjct: 1 MNSTPPTLNTIGFIGLGNMGAAMAGHLCKAGYTVLAWARNASTFEALAD-----IPLVPQ 55
Query: 270 TSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKK---LIPLLSKGDIIIDGGNSQYLDTQKW 440
S++ + + R + L V V + + + G II+D
Sbjct: 56 PSIEALCAST---RLVALNVTNTADVQSLLFRDGGIAQHAQPGSIIVDFSTIDAAAVADI 112
Query: 441 CKELSGTGILYVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQ 578
++L G+ Y+ VSGG GAR S+M GG AA+ I+ + +
Sbjct: 113 ARQLKSRGVDYIDCPVSGGAAGARAATLSMMAGGDLAAFNRIEPMLK 159
>UniRef50_A0LDJ3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Magnetococcus sp. MC-1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Magnetococcus sp. (strain MC-1)
Length = 292
Score = 35.9 bits (79), Expect = 0.78
Identities = 33/146 (22%), Positives = 62/146 (42%), Gaps = 3/146 (2%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNE--AKGTKVIGATSLDDMVS 293
I IGL +MG + + + GY +C +NR ++++ F+ T AT D MV
Sbjct: 4 IGFIGLGIMGSAMANSCHHAGYQLCVYNRGHARLKPFIDRSIPTAATPQALATQSDYMVI 63
Query: 294 KLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILY 473
+ P ++ +++ V G ++I+ +Q+ + G +
Sbjct: 64 MVSDPAALLEVLQGPVGV-------CSADLTGKVVINASTVSVEASQQAATLVEQVGGAF 116
Query: 474 VGMGVSGGEDGARYGPSL-MPGGHPA 548
+ VSG + A+ G + + GGH A
Sbjct: 117 LDAPVSGSKIPAQTGKLVFLAGGHHA 142
>UniRef50_Q1EPJ1 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding domain-containing protein; n=8;
Magnoliophyta|Rep: 6-phosphogluconate dehydrogenase
NAD-binding domain-containing protein - Musa acuminata
(Banana)
Length = 314
Score = 35.9 bits (79), Expect = 0.78
Identities = 38/160 (23%), Positives = 65/160 (40%), Gaps = 5/160 (3%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAK--GTKVIGATSLDDMVS 293
+ IG VMG + + GY V + RT SK + + A + A S D + +
Sbjct: 18 VGWIGAGVMGAAMAARLQTAGYAVAIYARTPSKADHLRRLGAHLVPSPADAARSADVLFT 77
Query: 294 KLKRPRKI--VLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGI 467
+ P + LL A A + + G +++D +S ++ G
Sbjct: 78 MVGHPFDVREALLDPASGA--------LAAIPPGGVLVDCTSSDPALAREVAAAARARGC 129
Query: 468 LYVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAI 584
V VSGG+ GAR G +++ GG + +F+A+
Sbjct: 130 WAVDAPVSGGDVGARDGTLAILAGGDEGVVHWLSPLFEAL 169
>UniRef50_UPI0000EBE4FC Cluster: PREDICTED: hypothetical protein;
n=1; Bos taurus|Rep: PREDICTED: hypothetical protein -
Bos taurus
Length = 351
Score = 35.5 bits (78), Expect = 1.0
Identities = 14/43 (32%), Positives = 25/43 (58%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAK 248
I +GL +MG ++ N+ G+ V +NRT K + F++ A+
Sbjct: 20 IGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQEGAR 62
>UniRef50_A5WG80 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Moraxellaceae|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Psychrobacter sp. PRwf-1
Length = 309
Score = 35.5 bits (78), Expect = 1.0
Identities = 36/150 (24%), Positives = 64/150 (42%), Gaps = 1/150 (0%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
++ IGL MG ++ ++ V +NR K GT+ A SL+ VS
Sbjct: 18 VSFIGLGAMGHHMAKHLVGSFDTVMVYNRNFDKATAHAAE--FGTQ---AVSLEQAVS-- 70
Query: 300 KRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVG 479
I + VD+ +++ +P L+ G + +D + + + +L+ G ++
Sbjct: 71 --ADVIFSCLPTSQVVDDLIEQALPHLNDGSVWVDCTSGVPENAKASQAKLNAAGCEFLD 128
Query: 480 MGVSGGEDGARYGP-SLMPGGHPAAWPHIK 566
VSG GA G ++M GG A + K
Sbjct: 129 APVSGQTSGADSGTLTVMVGGSAKALAYAK 158
>UniRef50_Q49A26 Cluster: Cytokine-like nuclear factor n-pac; n=46;
Euteleostomi|Rep: Cytokine-like nuclear factor n-pac -
Homo sapiens (Human)
Length = 553
Score = 35.5 bits (78), Expect = 1.0
Identities = 14/43 (32%), Positives = 25/43 (58%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAK 248
I +GL +MG ++ N+ G+ V +NRT K + F++ A+
Sbjct: 270 IGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQEGAR 312
>UniRef50_Q89HA0 Cluster: Oxidoreductase; n=1; Bradyrhizobium
japonicum|Rep: Oxidoreductase - Bradyrhizobium japonicum
Length = 313
Score = 35.1 bits (77), Expect = 1.4
Identities = 40/156 (25%), Positives = 65/156 (41%), Gaps = 7/156 (4%)
Frame = +3
Query: 93 KKMPQNEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGAT 272
K PQ + +GL +MG + + GY V +NR+ KV ++ A+ GA+
Sbjct: 17 KANPQRDERFGYLGLGLMGTPMTRRLLKAGYQVSVWNRSEGKVVPIVEAGARH----GAS 72
Query: 273 SLDDMVSKLKRPRKIVLLVKAGFAVDEFV---KKLIPLLSKGDIIIDGGN---SQYLDTQ 434
D M + + V AV+E + + L G +++D + D
Sbjct: 73 PRDVMAGS----DIVFMCVTDAAAVEEVIFGAEGLSTAPGAGKLVVDFSSIHPDAARDLA 128
Query: 435 KWCKELSGTGILYVGMGVSGGEDGARYGP-SLMPGG 539
K +G G ++ VSGG GA G ++M GG
Sbjct: 129 TRLKAANGAG--WIDAPVSGGTKGAEEGTLAIMAGG 162
>UniRef50_Q0EVH7 Cluster: Glutamyl-tRNA reductase; n=1;
Thermoanaerobacter ethanolicus X514|Rep: Glutamyl-tRNA
reductase - Thermoanaerobacter ethanolicus X514
Length = 395
Score = 35.1 bits (77), Expect = 1.4
Identities = 20/46 (43%), Positives = 26/46 (56%)
Frame = +3
Query: 126 LIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVI 263
+IGL MGQN + N+ DKG V NRT SK E LK + ++
Sbjct: 183 VIGLGEMGQNAMKNLLDKGADVFVTNRTFSKAIE-LKEQIPQINIV 227
>UniRef50_Q6D9X4 Cluster: Putative 2-hydroxy-3-oxopropionate
reductase; n=1; Pectobacterium atrosepticum|Rep:
Putative 2-hydroxy-3-oxopropionate reductase - Erwinia
carotovora subsp. atroseptica (Pectobacterium
atrosepticum)
Length = 297
Score = 34.7 bits (76), Expect = 1.8
Identities = 35/137 (25%), Positives = 66/137 (48%), Gaps = 4/137 (2%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
++L+G+ V+G+ + L + + + + FNRT SK + GA ++ ++
Sbjct: 5 VSLVGVGVLGKAISLRLLQRHFSLSVFNRTHSKTNDVAAE--------GAQAVPELHQLF 56
Query: 300 KRPRKIVLL-VKAGFAV-DEFVKK-LIPLLSKGDIIIDGGNSQYLDTQKWCKE-LSGTGI 467
+ ++IVL+ +K A+ D F + +I LS + ++ + +W + G
Sbjct: 57 TQEKQIVLICLKDAEAIRDVFQSEDVIHKLSLYRPLFLNISTIGPEESRWMETFFHQHGA 116
Query: 468 LYVGMGVSGGEDGARYG 518
YV VSGG +GAR G
Sbjct: 117 HYVECPVSGGPEGARQG 133
>UniRef50_Q2JNP7 Cluster: Prephenate dehydrogenase; n=1;
Synechococcus sp. JA-2-3B'a(2-13)|Rep: Prephenate
dehydrogenase - Synechococcus sp. (strain
JA-2-3B'a(2-13)) (Cyanobacteria bacteriumYellowstone
B-Prime)
Length = 296
Score = 34.7 bits (76), Expect = 1.8
Identities = 27/101 (26%), Positives = 48/101 (47%), Gaps = 3/101 (2%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAK---GTKVIGATSLDDMV 290
IA++GL ++G +L L + +KGY V +R + ++ L+ A GT++ D +
Sbjct: 3 IAIVGLGLIGGSLALKLTEKGYSVWGISRNPATCKQALERGAVQGCGTELAQLARFDPQM 62
Query: 291 SKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGN 413
+ P + VL A L+P LS ++ D G+
Sbjct: 63 VLICTPLEQVLATLAA---------LLPYLSAETVVSDVGS 94
>UniRef50_Q01QM2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Solibacter usitatus Ellin6076|Rep: 3-hydroxyisobutyrate
dehydrogenase - Solibacter usitatus (strain Ellin6076)
Length = 298
Score = 34.7 bits (76), Expect = 1.8
Identities = 40/165 (24%), Positives = 70/165 (42%), Gaps = 5/165 (3%)
Frame = +3
Query: 114 ADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVS 293
A++ +GL +MG + N+ G+ V ++ T K + L +E KG V AT D
Sbjct: 2 ANLGFLGLGLMGYPMARNLLRAGHNVAVWSHTSDKARK-LADEEKG--VFCATPRD---- 54
Query: 294 KLKRPRKIVLLVKAGFAVDEFV----KKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGT 461
+ +V L A+ V + LI L G +++D D+++ L
Sbjct: 55 -VGAGADVVFLCVGDTAMAREVILGGQGLIQGLRAGAVVVDCSTIAVADSREIGAALKAK 113
Query: 462 GILYVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAICAK 593
+ ++ V+G GA G + M GG A + I+ + + K
Sbjct: 114 SVDFLDAPVTGSTPGAESGNLTFMIGGDEAVFSKIRPLLDPMGKK 158
>UniRef50_A6F020 Cluster: Putative uncharacterized protein; n=1;
Marinobacter algicola DG893|Rep: Putative
uncharacterized protein - Marinobacter algicola DG893
Length = 286
Score = 34.7 bits (76), Expect = 1.8
Identities = 32/134 (23%), Positives = 65/134 (48%), Gaps = 1/134 (0%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
+++IG+ MG+++ +++ DKG+ V A++ + + + KN G KV+ SL + V+K
Sbjct: 3 VSIIGVGDMGRDIAVHVRDKGHDVIAYDISEERRSDVAKN---GIKVV--ESLAEAVAK- 56
Query: 300 KRPRKIVLLVKAGFAVDEFV-KKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYV 476
++ L++ A E V ++++ G ++ + Q E G+ +V
Sbjct: 57 ---AEVHLVIVATDEQSETVTREILESGPAGSTVVILATNSPKTMQVLAAECEDKGLGFV 113
Query: 477 GMGVSGGEDGARYG 518
V G GA+ G
Sbjct: 114 DAPVVFGRQGAKEG 127
>UniRef50_Q0VIN9 Cluster: AROM polypeptide; n=2; Tetrahymena
thermophila|Rep: AROM polypeptide - Tetrahymena
thermophila
Length = 1577
Score = 34.7 bits (76), Expect = 1.8
Identities = 23/78 (29%), Positives = 40/78 (51%), Gaps = 1/78 (1%)
Frame = +3
Query: 105 QNEADIAL-IGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLD 281
Q++ AL IG ++ +N G+ +NRT K+E+F+ + + G +S+D
Sbjct: 1413 QSKQKFALVIGAGATTLTMVYCLNMLGFQTLIYNRTYQKIEKFI---GRNGVIKGFSSID 1469
Query: 282 DMVSKLKRPRKIVLLVKA 335
D+V LK+ + L V A
Sbjct: 1470 DLVLYLKQNLHVQLSVIA 1487
>UniRef50_A0NE61 Cluster: ENSANGP00000030787; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000030787 - Anopheles gambiae
str. PEST
Length = 49
Score = 34.7 bits (76), Expect = 1.8
Identities = 12/19 (63%), Positives = 16/19 (84%)
Frame = +3
Query: 561 IKEIFQAICAKANDEPCCD 617
+KE+F AICAK+N PCC+
Sbjct: 1 MKEMFPAICAKSNGNPCCE 19
>UniRef50_Q8TT25 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Methanosarcina|Rep: 3-hydroxyisobutyrate dehydrogenase -
Methanosarcina acetivorans
Length = 300
Score = 34.7 bits (76), Expect = 1.8
Identities = 14/42 (33%), Positives = 24/42 (57%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEA 245
+ +IGL +MG + N+ +GY V +NRT K + ++ A
Sbjct: 12 VGVIGLGIMGSSFASNLLSRGYNVHVYNRTKEKAQPLIERGA 53
>UniRef50_Q9JYH6 Cluster: 3-hydroxyacid dehydrogenase; n=5;
Proteobacteria|Rep: 3-hydroxyacid dehydrogenase -
Neisseria meningitidis serogroup B
Length = 289
Score = 34.3 bits (75), Expect = 2.4
Identities = 45/168 (26%), Positives = 71/168 (42%), Gaps = 3/168 (1%)
Frame = +3
Query: 99 MPQNE-ADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATS 275
M NE A I IGL MG ++ + D G V +NR+ K AKG KV G T
Sbjct: 1 MSANEYAQIGWIGLGQMGLPMVTRLLDGGIEVGVYNRSPDKTAPI---SAKGAKVYGNT- 56
Query: 276 LDDMVSKLKRPRKIVLLVKAGF-AVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKEL 452
++L R ++ L+ + + AV + + + L+ G II++ + +
Sbjct: 57 -----AELVRDYPVIFLMVSDYAAVCDILNGVRDGLA-GKIIVNMSTISPTENLAVKALV 110
Query: 453 SGTGILYVGMGVSGGEDGARYGPSL-MPGGHPAAWPHIKEIFQAICAK 593
G + VSG A G L + GG A +++IF + K
Sbjct: 111 EAAGGQFAEAPVSGSVGPATNGTLLILFGGSEAVLNPLQKIFSLVGKK 158
>UniRef50_Q39FA8 Cluster: 2-hydroxy-3-oxopropionate reductase; n=22;
Burkholderiales|Rep: 2-hydroxy-3-oxopropionate reductase
- Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 287
Score = 34.3 bits (75), Expect = 2.4
Identities = 40/158 (25%), Positives = 69/158 (43%), Gaps = 8/158 (5%)
Frame = +3
Query: 144 MGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKLKRPRKIVL 323
MG +I ++ G+ V +NR+ K E +K+ G +V+G +R + +
Sbjct: 1 MGAPMIRHLLAAGHRVSVWNRSRDKAEALVKD---GAQVVGTPR-----ELAERVDTVFV 52
Query: 324 LVKAGFAVDEFVKKLIPLLSKGDI-------IIDGGNSQYLDTQKWCKELSGTGILYVGM 482
V G AV + V LLS GD I+D + T+ + + G+ +V
Sbjct: 53 CVLDGRAVGDVVFGEHGLLS-GDAAARRLQRIVDHSSIPPAATRDYAARATALGVGWVDA 111
Query: 483 GVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAICAK 593
VSGG GA+ G ++M GG A ++ + ++
Sbjct: 112 PVSGGVPGAQAGTLAVMAGGRAADLDAVRPLIDTYASR 149
>UniRef50_Q392H4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=8; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia sp. (strain
383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
/ R18194))
Length = 292
Score = 34.3 bits (75), Expect = 2.4
Identities = 14/40 (35%), Positives = 26/40 (65%)
Frame = +3
Query: 105 QNEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVE 224
+N +A++G+ VMG + N+ +G+ V A+NRT +K +
Sbjct: 7 RNATTVAVLGIGVMGAPIARNLARQGFTVRAWNRTRAKAD 46
>UniRef50_Q19TN0 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=11; Francisella tularensis|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Francisella tularensis subsp. mediasiatica
Length = 295
Score = 34.3 bits (75), Expect = 2.4
Identities = 16/47 (34%), Positives = 27/47 (57%)
Frame = +3
Query: 99 MPQNEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKN 239
M + + +IGL MG +I ++ GY + NRT +K E++L+N
Sbjct: 1 MAKMSKQVGIIGLGNMGSVVIDHLLTSGYEIFIHNRTKAKAEKWLRN 47
>UniRef50_A6LJ59 Cluster: NAD/NADP octopine/nopaline dehydrogenase;
n=1; Thermosipho melanesiensis BI429|Rep: NAD/NADP
octopine/nopaline dehydrogenase - Thermosipho
melanesiensis BI429
Length = 359
Score = 34.3 bits (75), Expect = 2.4
Identities = 21/100 (21%), Positives = 48/100 (48%), Gaps = 5/100 (5%)
Frame = +3
Query: 117 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKN-----EAKGTKVIGATSLD 281
+I++IG G L + +G+ V +NR++ ++ F+K+ E + + ++
Sbjct: 2 NISVIGAGNGGLALAGFLTLRGFKVTLYNRSIKRISSFMKSKIIRLEGEINATVKIFNVT 61
Query: 282 DMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIII 401
+ + + K+V++V FA + +K+ P + I I
Sbjct: 62 NDIKEALEDAKLVMIVVPAFAHADIAEKIYPYVEDDQIFI 101
>UniRef50_Q84VC8 Cluster: Gamma hydroxybutyrate dehydrogenase-like
protein; n=3; Magnoliophyta|Rep: Gamma hydroxybutyrate
dehydrogenase-like protein - Oryza sativa subsp.
japonica (Rice)
Length = 293
Score = 34.3 bits (75), Expect = 2.4
Identities = 13/39 (33%), Positives = 25/39 (64%)
Frame = +3
Query: 117 DIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFL 233
++ +GL +MG+ + N+ G+ V +NRT+SK +E +
Sbjct: 2 EVGFLGLGIMGKAMAANLLRHGFRVTVWNRTLSKCQELV 40
>UniRef50_Q971W0 Cluster: Putative HTH-type transcriptional
regulatory protein ST1268; n=1; Sulfolobus tokodaii|Rep:
Putative HTH-type transcriptional regulatory protein
ST1268 - Sulfolobus tokodaii
Length = 299
Score = 34.3 bits (75), Expect = 2.4
Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Frame = +3
Query: 108 NEADIAL-IGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDD 284
+E DI L A + ++LN+N+KGY V N T + KN+ K + A ++
Sbjct: 190 DEKDINLETQTASLSDKIMLNLNEKGYKVVKMNFTAVDIIA-SKNDKKLLFSVEADNVSK 248
Query: 285 MVSKLKRPRKIVLLVKAGFAV 347
+ K +KI +KA V
Sbjct: 249 SLRKFNEAKKITSKIKASLIV 269
>UniRef50_P0ABQ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=25;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Escherichia coli O6
Length = 294
Score = 34.3 bits (75), Expect = 2.4
Identities = 36/158 (22%), Positives = 66/158 (41%), Gaps = 3/158 (1%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLK--NEAKGTKVIGATSLDDMVS 293
+ IGL +MG+ + N+ GY + +R + + + E T A D +++
Sbjct: 3 VGFIGLGIMGKPMSKNLLKAGYSLVVADRNPEAIADVIAAGAETASTAKAIAEQCDVIIT 62
Query: 294 KLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILY 473
L + + + E K G ++ID + L +++ + L GI
Sbjct: 63 MLPNSPHVKEVALGENGIIEGAK-------PGTVLIDMSSIAPLASREISEALKAKGIDM 115
Query: 474 VGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAI 584
+ VSGGE A G S+M GG A + ++ +A+
Sbjct: 116 LDAPVSGGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAM 153
>UniRef50_UPI0000E46E06 Cluster: PREDICTED: similar to MGC107852
protein; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to MGC107852 protein -
Strongylocentrotus purpuratus
Length = 432
Score = 33.9 bits (74), Expect = 3.1
Identities = 16/43 (37%), Positives = 23/43 (53%)
Frame = +3
Query: 93 KKMPQNEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKV 221
K + E I IGL +MG + +N+ G+ V +NRT KV
Sbjct: 355 KDIKPTEKKIGFIGLGLMGTGMAMNLIKAGHKVTVWNRTSEKV 397
>UniRef50_Q89RT2 Cluster: Bll2680 protein; n=1; Bradyrhizobium
japonicum|Rep: Bll2680 protein - Bradyrhizobium
japonicum
Length = 300
Score = 33.9 bits (74), Expect = 3.1
Identities = 37/165 (22%), Positives = 68/165 (41%), Gaps = 4/165 (2%)
Frame = +3
Query: 99 MPQNEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSL 278
M ++A IG+ MG + + + GY V AF+R+ ++ NEA+ + A S
Sbjct: 1 MTDASRNVAFIGIGKMGLPMSVLVAKAGYAVTAFDRSAART-----NEARAQGISIAASP 55
Query: 279 DDMVSKLKRPRKIVLLVKAGFAVDEFV---KKLIPLLSKGDIIIDGGNSQYLDTQKWCKE 449
DD VS ++ + A+ + +I ++ G ++I+ + +
Sbjct: 56 DDAVS---GKEAVITSLPDDTALRGALLGPAGVIAAMAPGAVLIETSTVSVEASTEVAAS 112
Query: 450 LSGTGILYVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQA 581
G+LY+ VSG G + G A+ + K +F A
Sbjct: 113 AQARGVLYLRAPVSGNASIVHTGALTCFVSGPKDAFDNAKPLFAA 157
>UniRef50_Q5LQR0 Cluster: 6-phosphogluconate dehydrogenase domain
protein; n=14; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase domain protein - Silicibacter pomeroyi
Length = 302
Score = 33.9 bits (74), Expect = 3.1
Identities = 38/167 (22%), Positives = 72/167 (43%), Gaps = 2/167 (1%)
Frame = +3
Query: 90 LKKMPQNEADIALIGLAVMGQNLILNMNDKGYVVCAF-NRTVSKVEEFLKNEAKGTKVIG 266
+K+ ++A I IGL +MG ++ + G+ V NR + VE L A T+
Sbjct: 1 MKENNMDKAHIGFIGLGLMGAAMVECLQKAGHAVTVLGNRDRTGVEAALARGA--TEAAH 58
Query: 267 ATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCK 446
A ++ + + V++ D+ V + +G ++ID G S T++
Sbjct: 59 ARAVAEASDIVMLCMGTSAQVESRIYGDDGV---LAGTREGQVVIDFGTSLPASTRRIGG 115
Query: 447 ELSGTGILYVGMGVSGGEDGARYG-PSLMPGGHPAAWPHIKEIFQAI 584
+L+G G Y+ + AR G ++M G A + +K + +
Sbjct: 116 DLAGKGATYLDAPLGRTPAHARDGLLNIMCSGDKATFDRVKPVLHTL 162
>UniRef50_Q2JSE7 Cluster: Prephenate dehydrogenase; n=6;
Cyanobacteria|Rep: Prephenate dehydrogenase -
Synechococcus sp. (strain JA-3-3Ab) (Cyanobacteria
bacteriumYellowstone A-Prime)
Length = 286
Score = 33.9 bits (74), Expect = 3.1
Identities = 27/101 (26%), Positives = 48/101 (47%), Gaps = 3/101 (2%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAK---GTKVIGATSLDDMV 290
IA++GL ++G +L L ++++GY V +R + + L+ A GT + D V
Sbjct: 3 IAIVGLGLIGGSLALKLSEEGYPVWGISRNRATCQAVLERGALQGCGTDLAQLADFDPQV 62
Query: 291 SKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGN 413
+ P + VL+ A L+P LS ++ D G+
Sbjct: 63 VVICTPLEQVLVTLAA---------LVPHLSPQTVVSDVGS 94
>UniRef50_Q21ZN3 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Rhodoferax ferrireducens T118|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Rhodoferax ferrireducens (strain DSM 15236 / ATCC
BAA-621 / T118)
Length = 292
Score = 33.9 bits (74), Expect = 3.1
Identities = 35/160 (21%), Positives = 61/160 (38%), Gaps = 4/160 (2%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
I LIGL +MG + N+ G+ + + L + +GA + +
Sbjct: 9 IGLIGLGLMGHGIGRNLLKNGFALTVMGNVNRAPVDSLVS-------LGANESKSVAELV 61
Query: 300 KRPRKIVLLVKAGFAVDEFVKK---LIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGIL 470
++L V V+ + + ++ + G I+ID SQ + L G L
Sbjct: 62 DASDVVMLCVTGSPQVESLMNRDQGILQSIRPGQIVIDCSTSQPSSSAIINAALLEAGAL 121
Query: 471 YVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAIC 587
+V + A G ++M G P HI+ + QA C
Sbjct: 122 FVDAPLGRTPAEAEAGKLNVMVGATPQLLEHIRPVLQAFC 161
>UniRef50_Q1GJB9 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding; n=1; Silicibacter sp. TM1040|Rep:
6-phosphogluconate dehydrogenase NAD-binding -
Silicibacter sp. (strain TM1040)
Length = 304
Score = 33.9 bits (74), Expect = 3.1
Identities = 38/159 (23%), Positives = 63/159 (39%), Gaps = 3/159 (1%)
Frame = +3
Query: 126 LIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKLKR 305
+IGL MG + ++ G+ V ++ + E T A D V L
Sbjct: 11 VIGLGAMGLGMARSLLKAGFAVSGYDPAETARENAAAAGVWLTADTDAVFADCDVIVLSL 70
Query: 306 P--RKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVG 479
P + ++ +V+A A + +I+D S+ ++ ELS G ++
Sbjct: 71 PTAQHVLAVVQAAQAAGHLAQT-----GAARVIVDTSTSEAATSRTLAAELSALGHGFLD 125
Query: 480 MGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAICAK 593
VSGG GA G S+M GG + +A+ AK
Sbjct: 126 APVSGGPAGAASGQLSVMLGGETQWLEAARPALEAMAAK 164
>UniRef50_UPI000155DAA0 Cluster: PREDICTED: similar to Transmembrane
protein 61; n=2; Eutheria|Rep: PREDICTED: similar to
Transmembrane protein 61 - Equus caballus
Length = 239
Score = 33.5 bits (73), Expect = 4.2
Identities = 25/82 (30%), Positives = 42/82 (51%), Gaps = 5/82 (6%)
Frame = +3
Query: 315 IVLLVKAGF-AVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVG---- 479
+V+++ G A+ V ++ L+ ++ DG S+ T ++C LSGT +L G
Sbjct: 54 VVMVMMVGVTALGLMVVVVVVLMVIMAVVCDG--SRAASTLRYCLTLSGTVLLVAGTLCF 111
Query: 480 MGVSGGEDGARYGPSLMPGGHP 545
S G+ GA+ G +P GHP
Sbjct: 112 AWWSEGDAGAQPGQPALPTGHP 133
>UniRef50_Q98I20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Alphaproteobacteria|Rep: 3-hydroxyisobutyrate
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 305
Score = 33.5 bits (73), Expect = 4.2
Identities = 40/161 (24%), Positives = 67/161 (41%), Gaps = 3/161 (1%)
Frame = +3
Query: 123 ALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEF--LKNEAKGTKVIGATSLDDMVSK 296
A IGL +G NL ++ G+ + F+R + VE L A + A + ++
Sbjct: 6 AFIGLGHLGGNLAPSLIRNGFAITVFDRDPAAVERLVTLGATAANSPAEAAARAGNAITC 65
Query: 297 LKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYV 476
L P KI V AG L+ L KG I+ + + + S G+ +
Sbjct: 66 LPSP-KISEAVLAG------PGGLLEGLPKGGTWIEMSTNGRDEIMRLAALASAEGVETL 118
Query: 477 GMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAICAKA 596
V+GG A G + + GG A + + +A+CA++
Sbjct: 119 ECPVTGGVHLAAVGKITALVGGDAALYERHRAAIEAMCARS 159
>UniRef50_Q3W9W7 Cluster: 6-phosphogluconate dehydrogenase, NAD
binding domain; n=2; Frankia sp. EAN1pec|Rep:
6-phosphogluconate dehydrogenase, NAD binding domain -
Frankia sp. EAN1pec
Length = 286
Score = 33.5 bits (73), Expect = 4.2
Identities = 27/109 (24%), Positives = 47/109 (43%), Gaps = 2/109 (1%)
Frame = +3
Query: 264 GATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDI-IIDGGNSQYLDTQKW 440
G T LDD+ + + +VL + G ++ + L + ++D Q+
Sbjct: 43 GTTHLDDLAAVARHAEVVVLSLPDGVISEKVARGLAETADRRVTHVVDTSTIGVSAAQRI 102
Query: 441 CKELSGTGILYVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAI 584
L+ +GI YV VSGG GAR ++M G A ++ + A+
Sbjct: 103 TDLLAASGIGYVDAPVSGGVTGARARTLTVMYAGTDDACARVEPVLAAL 151
>UniRef50_Q0S5S3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 299
Score = 33.5 bits (73), Expect = 4.2
Identities = 28/145 (19%), Positives = 63/145 (43%), Gaps = 1/145 (0%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
+ +GL +G ++ ++ G+ V ++ + V+ + +GA S+
Sbjct: 5 VGFVGLGNIGGRVVAHLVKAGHDVAVYDLNTAAVDAAV--------ALGARSVASPGEAA 56
Query: 300 KRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVG 479
++ + L + V+ V ++ ++G +I+D T++ ++ G ++
Sbjct: 57 RKAEALFLSLPTPAIVEGVVADVLQQGNQGLVIVDHSTIDPDTTRRLAQDAQVAGACFLD 116
Query: 480 MGVSGGEDGARYGP-SLMPGGHPAA 551
VSGG GA G ++M GG A+
Sbjct: 117 APVSGGVQGAEAGTLAVMLGGDEAS 141
>UniRef50_A0G5F9 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Burkholderia|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia phymatum
STM815
Length = 307
Score = 33.5 bits (73), Expect = 4.2
Identities = 35/160 (21%), Positives = 66/160 (41%), Gaps = 5/160 (3%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIG--ATSLDDMVS 293
+ +G+ MG+ + + + G+ + F+R + V E A+ + A S + +
Sbjct: 15 LGFVGVGTMGRPMARRLIEAGHALVVFDRDEAAVAELKAIGAQAAASVREIADSARIVFT 74
Query: 294 KLKRPR--KIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGI 467
L P + V L G +K L+ L + G + ++ + L G+
Sbjct: 75 SLPTPAIFRQVALGDGGLIEGSAIKVLVDLSTVGSRV----------EKEVAQGLLAKGV 124
Query: 468 LYVGMGVSGGEDGARYGP-SLMPGGHPAAWPHIKEIFQAI 584
V VSGG GA+ G ++M G P A ++ +F +
Sbjct: 125 ETVDAPVSGGAAGAKKGTLAIMAAGSPVALEEVRGLFDVL 164
>UniRef50_Q8RB99 Cluster: NAD/NADP octopine/nopaline dehydrogenas;
n=5; Bacteria|Rep: NAD/NADP octopine/nopaline
dehydrogenas - Thermoanaerobacter tengcongensis
Length = 366
Score = 33.1 bits (72), Expect = 5.5
Identities = 26/98 (26%), Positives = 49/98 (50%), Gaps = 5/98 (5%)
Frame = +3
Query: 123 ALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKN---EAKG-TKVIGATSL-DDM 287
A+IG GQ + ++ KG+ V +NRT K+ ++ E +G + G +L D
Sbjct: 7 AVIGAGNGGQAIAGHLALKGFKVNLYNRTYEKLIPIIQRGGIELEGEVEGFGKLNLVTDD 66
Query: 288 VSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIII 401
+SK + ++L+ A ++L+P L +G I++
Sbjct: 67 ISKAVKDVDMILVAVPASAHAMIAEELLPYLQRGQIVV 104
>UniRef50_Q7JN85 Cluster: Twitchin; n=6; Bilateria|Rep: Twitchin -
Caenorhabditis elegans
Length = 6048
Score = 33.1 bits (72), Expect = 5.5
Identities = 17/47 (36%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Frame = +3
Query: 324 LVKAGFAVDEFVKKLIPLLSKGDII-IDGGNSQYLDTQKWCKELSGT 461
++K G +DE ++KL+ ++ K D+ I N Q DT KW EL +
Sbjct: 423 ILKNGKPIDEEMRKLVEVIIKDDVAEIVFKNPQLADTGKWALELGNS 469
>UniRef50_Q821V5 Cluster: UvrABC system protein C; n=9;
Chlamydiaceae|Rep: UvrABC system protein C -
Chlamydophila caviae
Length = 605
Score = 33.1 bits (72), Expect = 5.5
Identities = 15/30 (50%), Positives = 20/30 (66%)
Frame = +3
Query: 393 IIIDGGNSQYLDTQKWCKELSGTGILYVGM 482
I+IDGG +QY +K KEL+ TGI V +
Sbjct: 453 IVIDGGRAQYSQAKKTLKELNLTGIQVVSL 482
>UniRef50_UPI0001597301 Cluster: YfjR; n=1; Bacillus
amyloliquefaciens FZB42|Rep: YfjR - Bacillus
amyloliquefaciens FZB42
Length = 286
Score = 32.7 bits (71), Expect = 7.3
Identities = 15/43 (34%), Positives = 24/43 (55%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAK 248
IA++GL MG+ + N+ GY + +NRT K + L A+
Sbjct: 3 IAIVGLGNMGRPIAENIMKAGYSLTVYNRTKEKAADLLDKGAE 45
>UniRef50_Q1MPA3 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Lawsonia intracellularis PHE/MN1-00|Rep:
Pyrroline-5-carboxylate reductase - Lawsonia
intracellularis (strain PHE/MN1-00)
Length = 278
Score = 32.7 bits (71), Expect = 7.3
Identities = 25/91 (27%), Positives = 42/91 (46%)
Frame = +3
Query: 129 IGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKLKRP 308
+G A++ + + D G ++ +NRT K+ E KG + I D + L +
Sbjct: 20 MGSAILSSLVPMAHPDNGLILSGYNRTPEKLAPL---EEKGVQSI------DTIPNLIQQ 70
Query: 309 RKIVLLVKAGFAVDEFVKKLIPLLSKGDIII 401
I++L AV +K+ +P L G III
Sbjct: 71 NDIIILGTKPSAVVPILKECLPFLRPGHIII 101
>UniRef50_Q1B326 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein precursor; n=7; Bacteria|Rep:
6-phosphogluconate dehydrogenase, NAD-binding protein
precursor - Mycobacterium sp. (strain MCS)
Length = 299
Score = 32.7 bits (71), Expect = 7.3
Identities = 17/57 (29%), Positives = 27/57 (47%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMV 290
I IGL MG + N+ G+ V A+NR+ KV+ A+ + + D+V
Sbjct: 6 IGFIGLGNMGSAMAANLLAAGHDVTAYNRSPDKVDALSAEGARPARTVAEACQGDVV 62
>UniRef50_Q13VQ8 Cluster: Putative dehydrogenase/oxidoreductase
protein; n=2; Burkholderiales|Rep: Putative
dehydrogenase/oxidoreductase protein - Burkholderia
xenovorans (strain LB400)
Length = 300
Score = 32.7 bits (71), Expect = 7.3
Identities = 28/125 (22%), Positives = 56/125 (44%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
+ +IG+ +G + N+ D GY V + R ++ + F+ G +++ SL +V +
Sbjct: 9 VGIIGIGQLGSAIASNLLDMGYRVVGYRRNRNEAQAFVD---AGGELVDTPSL--VVQQA 63
Query: 300 KRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYVG 479
+ A AV E V ++PLL G +++ G + +++ TG +
Sbjct: 64 DFIFLCLPNESASNAVLEGVGGILPLLKDGKTVVEVGTYRKSFKLMQAEKIQATGANILE 123
Query: 480 MGVSG 494
+SG
Sbjct: 124 AELSG 128
>UniRef50_A7DWL2 Cluster: Putative dehydrogenase; n=1; Streptomyces
tendae|Rep: Putative dehydrogenase - Streptomyces tendae
Length = 293
Score = 32.7 bits (71), Expect = 7.3
Identities = 32/134 (23%), Positives = 56/134 (41%), Gaps = 1/134 (0%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
+A+IGL MG + L + G+ V FNR+ K E+ + A GA
Sbjct: 5 VAVIGLGGMGSGMALALLRAGFQVTVFNRSPQKAEQAARAGAAVAPSAGAAG-------- 56
Query: 300 KRPRKIVLLVKAGFAVDEFV-KKLIPLLSKGDIIIDGGNSQYLDTQKWCKELSGTGILYV 476
R ++L + AVDE + +++ L G +++D + L+ +G+ +
Sbjct: 57 AAARVVLLSLADEPAVDEVLFGEVVWQLQPGTVLVDTTTVSPSFARNTAVRLAASGVERL 116
Query: 477 GMGVSGGEDGARYG 518
V G + A G
Sbjct: 117 EACVMGNPEMAESG 130
>UniRef50_A3WMG5 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase; n=1; Idiomarina baltica OS145|Rep:
Probable 3-hydroxyisobutyrate dehydrogenase - Idiomarina
baltica OS145
Length = 284
Score = 32.7 bits (71), Expect = 7.3
Identities = 15/43 (34%), Positives = 25/43 (58%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAK 248
IA +GL MG + ++ D G+ + +NRT S+ E L+ A+
Sbjct: 4 IAFLGLGAMGIRMAQHLIDAGHSLTVWNRTESRAEPLLEQGAQ 46
>UniRef50_Q0QZA7 Cluster: Gp121; n=1; Phage Syn9|Rep: Gp121 - Phage
Syn9
Length = 218
Score = 32.7 bits (71), Expect = 7.3
Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 3/100 (3%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKL 299
+ +IGL MG+ + + G+ V F V K E + SL +V
Sbjct: 3 VGMIGLGRMGEGMSRRLITAGHEVHGFRNNVKKSEAQYEAGYISGYTTSLESLVQVVHSN 62
Query: 300 KRPRK---IVLLVKAGFAVDEFVKKLIPLLSKGDIIIDGG 410
K + + ++V V++ + +L+ +GDIIID G
Sbjct: 63 KTTGETPGVFMMVVPAETVEDTLNELLQFCVEGDIIIDHG 102
>UniRef50_A6SMD9 Cluster: Predicted protein; n=1; Botryotinia
fuckeliana B05.10|Rep: Predicted protein - Botryotinia
fuckeliana B05.10
Length = 663
Score = 32.7 bits (71), Expect = 7.3
Identities = 22/75 (29%), Positives = 40/75 (53%), Gaps = 3/75 (4%)
Frame = +3
Query: 183 YVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLDDMVSKLKRPR---KIVLLVKAGFAVDE 353
+V+ A T +++E LK E K ++ TS DM++++KR R +I +++ +
Sbjct: 183 HVINAMEATHQRIQE-LKKEVKSKELASTTSNSDMINEMKRKREEQRISSVIQGSPGLRR 241
Query: 354 FVKKLIPLLSKGDII 398
+ K P+ S G II
Sbjct: 242 NISK-HPVTSSGKII 255
>UniRef50_A1S4D3 Cluster: 23S rRNA (uracil-5-)-methyltransferase
rumA (EC 2.1.1.-) (23S rRNA(M-
5-U1939)-methyltransferase); n=5; Shewanella|Rep: 23S
rRNA (uracil-5-)-methyltransferase rumA (EC 2.1.1.-)
(23S rRNA(M- 5-U1939)-methyltransferase) - Shewanella
amazonensis (strain ATCC BAA-1098 / SB2B)
Length = 443
Score = 32.7 bits (71), Expect = 7.3
Identities = 21/80 (26%), Positives = 40/80 (50%), Gaps = 3/80 (3%)
Frame = +3
Query: 246 KGTKVIGATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLI--PLLSKGD-IIIDGGNS 416
+G +V+G + +MV++ K+ I L F + + L P L K D +++D +
Sbjct: 318 QGAEVVGVEGVPEMVAQAKQNAAINGLDNLSFYCADLSEDLAAEPWLGKIDKLLLDPARA 377
Query: 417 QYLDTQKWCKELSGTGILYV 476
++ KW K++ +LYV
Sbjct: 378 GAYESLKWLKKMKPAKVLYV 397
>UniRef50_Q8KL12 Cluster: Probable 6-phosphogluconate dehydrogenase
protein; n=1; Rhizobium etli CFN 42|Rep: Probable
6-phosphogluconate dehydrogenase protein - Rhizobium
etli (strain CFN 42 / ATCC 51251)
Length = 294
Score = 32.3 bits (70), Expect = 9.6
Identities = 35/149 (23%), Positives = 59/149 (39%), Gaps = 3/149 (2%)
Frame = +3
Query: 102 PQNEADIALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEEFLKNEAKGTKVIGATSLD 281
P+ +A IGL MG + ++ + V F+ + E F +G +
Sbjct: 3 PRKNLRVAFIGLGAMGGPMAQHLLSAQFEVTGFDLSAEARERFA--------AVGGVPAE 54
Query: 282 DMVSKLKRPRKIVLLVKAGFAVDEFVKK--LIPLLSKGDIIIDGGNSQYLDTQKWCKELS 455
+ V ++ G V + + K LS ++ID +S DT++ + L
Sbjct: 55 TVAEAFNGADVAVTMLPNGKIVQDALFKDGAWQSLSADALVIDMSSSAPNDTRELAERLH 114
Query: 456 GTGILYVGMGVSGGEDGARYGP-SLMPGG 539
G+ V VSGG A G ++M GG
Sbjct: 115 QKGLRLVDAPVSGGVKRAVEGSLTIMAGG 143
>UniRef50_Q8EZ84 Cluster: K+ transport systems, NAD-binding
component; n=4; Leptospira|Rep: K+ transport systems,
NAD-binding component - Leptospira interrogans
Length = 236
Score = 32.3 bits (70), Expect = 9.6
Identities = 13/36 (36%), Positives = 24/36 (66%)
Frame = +3
Query: 120 IALIGLAVMGQNLILNMNDKGYVVCAFNRTVSKVEE 227
IA+IGL G+ L++ +N+ G+ V A ++ + +EE
Sbjct: 14 IAVIGLGEFGKALVVYLNENGHEVTAIDKDIKIIEE 49
>UniRef50_Q31HA8 Cluster: GrpE chaparone protein; n=1;
Thiomicrospira crunogena XCL-2|Rep: GrpE chaparone
protein - Thiomicrospira crunogena (strain XCL-2)
Length = 186
Score = 32.3 bits (70), Expect = 9.6
Identities = 18/65 (27%), Positives = 36/65 (55%)
Frame = +3
Query: 225 EFLKNEAKGTKVIGATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPLLSKGDIIID 404
E + EA+ K + +L DM LKR ++ + FA+++FV +L+P+L ++ +D
Sbjct: 41 EEARKEAESQKELALRTLADM-ENLKRRTRMDVESAHKFALEKFVNELLPVLDSMEMGLD 99
Query: 405 GGNSQ 419
+ +
Sbjct: 100 ASSKE 104
>UniRef50_Q8IZN6 Cluster: ATP-binding cassette protein C4 splice
variant A; n=14; Tetrapoda|Rep: ATP-binding cassette
protein C4 splice variant A - Homo sapiens (Human)
Length = 1278
Score = 32.3 bits (70), Expect = 9.6
Identities = 15/45 (33%), Positives = 25/45 (55%)
Frame = -3
Query: 331 FTKRTIFLGLFSLDTMSSKEVAPITFVPLASFFRNSSTFDTVLLN 197
+ K + LG+F+L S+K + PI + ++F N D+V LN
Sbjct: 88 YWKSYLVLGIFTLIEESAKVIQPIFLGKIINYFENYDPMDSVALN 132
>UniRef50_O67463 Cluster: tRNA (guanine-N(1)-)-methyltransferase;
n=2; Aquifex aeolicus|Rep: tRNA
(guanine-N(1)-)-methyltransferase - Aquifex aeolicus
Length = 257
Score = 32.3 bits (70), Expect = 9.6
Identities = 20/65 (30%), Positives = 35/65 (53%), Gaps = 1/65 (1%)
Frame = +3
Query: 219 VEEFLKNEAKGTKVIGATSLDDMVSKLKRPRKIVLLVKAGFAVDEFVKKLIPL-LSKGDI 395
VE + K T+ G +V++L + +I+++ VDE VKK++ + +S GD
Sbjct: 78 VENYGKPFVLITEPWGEKLNQKLVNELSKKERIMIICGRYEGVDERVKKIVDMEISLGDF 137
Query: 396 IIDGG 410
I+ GG
Sbjct: 138 ILSGG 142
>UniRef50_O15439 Cluster: Multidrug resistance-associated protein 4;
n=105; Eumetazoa|Rep: Multidrug resistance-associated
protein 4 - Homo sapiens (Human)
Length = 1325
Score = 32.3 bits (70), Expect = 9.6
Identities = 15/45 (33%), Positives = 25/45 (55%)
Frame = -3
Query: 331 FTKRTIFLGLFSLDTMSSKEVAPITFVPLASFFRNSSTFDTVLLN 197
+ K + LG+F+L S+K + PI + ++F N D+V LN
Sbjct: 88 YWKSYLVLGIFTLIEESAKVIQPIFLGKIINYFENYDPMDSVALN 132
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 615,437,901
Number of Sequences: 1657284
Number of extensions: 11981198
Number of successful extensions: 32056
Number of sequences better than 10.0: 191
Number of HSP's better than 10.0 without gapping: 31019
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 31962
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 45221970467
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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