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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= NRPG0154
         (714 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC002651-1|AAH02651.1|  348|Homo sapiens arsA arsenite transport...   241   3e-70
AY304483-1|AAP45050.1|  348|Homo sapiens arsA arsenite transport...   241   3e-70
AK223363-1|BAD97083.1|  348|Homo sapiens arsA arsenite transport...   241   3e-70
AF047469-1|AAC03551.1|  348|Homo sapiens arsenite translocating ...   240   5e-70
U60276-1|AAC50731.1|  332|Homo sapiens hASNA-I protein.               238   3e-68
U41221-1|AAA82080.1|  887|Homo sapiens hMSH2 protein.                  31   5.4  
U04045-1|AAA61870.1|  934|Homo sapiens hMSH2 protein.                  31   5.4  
U03911-1|AAA18643.1|  934|Homo sapiens hMSH2 protein.                  31   5.4  
L47583-1|AAB59564.1|  934|Homo sapiens DNA mismatch repair prote...    31   5.4  
L47582-1|AAB59565.1|  934|Homo sapiens DNA mismatch repair prote...    31   5.4  
L47581-1|AAA76858.1|  934|Homo sapiens DNA mismatch repair prote...    31   5.4  
L47580-1|AAB59572.1|  810|Homo sapiens MSH2 protein.                   31   5.4  
BC021566-1|AAH21566.1|  934|Homo sapiens mutS homolog 2, colon c...    31   5.4  
AY601851-1|AAS99351.1|  934|Homo sapiens mutS homolog 2, colon c...    31   5.4  
AK222860-1|BAD96580.1|  878|Homo sapiens mutS homolog 2 variant ...    31   5.4  

>BC002651-1|AAH02651.1|  348|Homo sapiens arsA arsenite transporter,
           ATP-binding, homolog 1 (bacterial) protein.
          Length = 348

 Score =  241 bits (589), Expect(2) = 3e-70
 Identities = 113/150 (75%), Positives = 135/150 (90%)
 Frame = +3

Query: 264 AVQLSKVRESVLIISTDPAHNISDAFDQKFSKVPTKVKGFDNLFAMEIDPNVGLTELPEE 443
           AVQLSK RESVLIISTDPAHNISDAFDQKFSKVPTKVKG+DNLFAMEIDP++G+ ELP+E
Sbjct: 58  AVQLSKGRESVLIISTDPAHNISDAFDQKFSKVPTKVKGYDNLFAMEIDPSLGVAELPDE 117

Query: 444 YFEGESEAMRLDKGVMQEIVGAFPGIDEAMSYAEVMKLVKGMNFSAVVFDTAPTGHTLRL 623
           +FE E   + + K +MQE + AFPGIDEAMSYAEVM+LVKGMNFS VVFDTAPTGHTLRL
Sbjct: 118 FFE-EDNMLSMGKKMMQEAMSAFPGIDEAMSYAEVMRLVKGMNFSVVVFDTAPTGHTLRL 176

Query: 624 LSFPQVVERGLGKLMRLKSKVXPFINQIAS 713
           L+FP +VERGLG+LM++K+++ PFI+Q+ +
Sbjct: 177 LNFPTIVERGLGRLMQIKNQISPFISQMCN 206



 Score = 44.8 bits (101), Expect(2) = 3e-70
 Identities = 17/26 (65%), Positives = 22/26 (84%)
 Frame = +3

Query: 66  EDTKDFEPLEPSLKNVIDQKSLRWIF 143
           ED  D EPLEP+L N+I+Q+SL+WIF
Sbjct: 16  EDAPDVEPLEPTLSNIIEQRSLKWIF 41


>AY304483-1|AAP45050.1|  348|Homo sapiens arsA arsenite transporter,
           ATP-binding, homolog 1 (bacterial) protein.
          Length = 348

 Score =  241 bits (589), Expect(2) = 3e-70
 Identities = 113/150 (75%), Positives = 135/150 (90%)
 Frame = +3

Query: 264 AVQLSKVRESVLIISTDPAHNISDAFDQKFSKVPTKVKGFDNLFAMEIDPNVGLTELPEE 443
           AVQLSK RESVLIISTDPAHNISDAFDQKFSKVPTKVKG+DNLFAMEIDP++G+ ELP+E
Sbjct: 58  AVQLSKGRESVLIISTDPAHNISDAFDQKFSKVPTKVKGYDNLFAMEIDPSLGVAELPDE 117

Query: 444 YFEGESEAMRLDKGVMQEIVGAFPGIDEAMSYAEVMKLVKGMNFSAVVFDTAPTGHTLRL 623
           +FE E   + + K +MQE + AFPGIDEAMSYAEVM+LVKGMNFS VVFDTAPTGHTLRL
Sbjct: 118 FFE-EDNMLSMGKKMMQEAMSAFPGIDEAMSYAEVMRLVKGMNFSVVVFDTAPTGHTLRL 176

Query: 624 LSFPQVVERGLGKLMRLKSKVXPFINQIAS 713
           L+FP +VERGLG+LM++K+++ PFI+Q+ +
Sbjct: 177 LNFPTIVERGLGRLMQIKNQISPFISQMCN 206



 Score = 44.8 bits (101), Expect(2) = 3e-70
 Identities = 17/26 (65%), Positives = 22/26 (84%)
 Frame = +3

Query: 66  EDTKDFEPLEPSLKNVIDQKSLRWIF 143
           ED  D EPLEP+L N+I+Q+SL+WIF
Sbjct: 16  EDAPDVEPLEPTLSNIIEQRSLKWIF 41


>AK223363-1|BAD97083.1|  348|Homo sapiens arsA arsenite transporter,
           ATP-binding, homolog 1 variant protein.
          Length = 348

 Score =  241 bits (589), Expect(2) = 3e-70
 Identities = 113/150 (75%), Positives = 135/150 (90%)
 Frame = +3

Query: 264 AVQLSKVRESVLIISTDPAHNISDAFDQKFSKVPTKVKGFDNLFAMEIDPNVGLTELPEE 443
           AVQLSK RESVLIISTDPAHNISDAFDQKFSKVPTKVKG+DNLFAMEIDP++G+ ELP+E
Sbjct: 58  AVQLSKGRESVLIISTDPAHNISDAFDQKFSKVPTKVKGYDNLFAMEIDPSLGVAELPDE 117

Query: 444 YFEGESEAMRLDKGVMQEIVGAFPGIDEAMSYAEVMKLVKGMNFSAVVFDTAPTGHTLRL 623
           +FE E   + + K +MQE + AFPGIDEAMSYAEVM+LVKGMNFS VVFDTAPTGHTLRL
Sbjct: 118 FFE-EDNMLSMGKKMMQEAMSAFPGIDEAMSYAEVMRLVKGMNFSVVVFDTAPTGHTLRL 176

Query: 624 LSFPQVVERGLGKLMRLKSKVXPFINQIAS 713
           L+FP +VERGLG+LM++K+++ PFI+Q+ +
Sbjct: 177 LNFPTIVERGLGRLMQIKNQISPFISQMCN 206



 Score = 44.8 bits (101), Expect(2) = 3e-70
 Identities = 17/26 (65%), Positives = 22/26 (84%)
 Frame = +3

Query: 66  EDTKDFEPLEPSLKNVIDQKSLRWIF 143
           ED  D EPLEP+L N+I+Q+SL+WIF
Sbjct: 16  EDAPDVEPLEPTLSNIIEQRSLKWIF 41


>AF047469-1|AAC03551.1|  348|Homo sapiens arsenite translocating
           ATPase protein.
          Length = 348

 Score =  240 bits (588), Expect(2) = 5e-70
 Identities = 113/148 (76%), Positives = 134/148 (90%)
 Frame = +3

Query: 264 AVQLSKVRESVLIISTDPAHNISDAFDQKFSKVPTKVKGFDNLFAMEIDPNVGLTELPEE 443
           AVQLSK RESVLIISTDPAHNISDAFDQKFSKVPTKVKG+DNLFAMEIDP++G+ ELP+E
Sbjct: 58  AVQLSKGRESVLIISTDPAHNISDAFDQKFSKVPTKVKGYDNLFAMEIDPSLGVAELPDE 117

Query: 444 YFEGESEAMRLDKGVMQEIVGAFPGIDEAMSYAEVMKLVKGMNFSAVVFDTAPTGHTLRL 623
           +FE E   + + K +MQE + AFPGIDEAMSYAEVM+LVKGMNFS VVFDTAPTGHTLRL
Sbjct: 118 FFE-EDNMLSMGKKMMQEAMSAFPGIDEAMSYAEVMRLVKGMNFSVVVFDTAPTGHTLRL 176

Query: 624 LSFPQVVERGLGKLMRLKSKVXPFINQI 707
           L+FP +VERGLG+LM++K+++ PFI+Q+
Sbjct: 177 LNFPTIVERGLGRLMQIKNQISPFISQM 204



 Score = 44.8 bits (101), Expect(2) = 5e-70
 Identities = 17/26 (65%), Positives = 22/26 (84%)
 Frame = +3

Query: 66  EDTKDFEPLEPSLKNVIDQKSLRWIF 143
           ED  D EPLEP+L N+I+Q+SL+WIF
Sbjct: 16  EDAPDVEPLEPTLSNIIEQRSLKWIF 41


>U60276-1|AAC50731.1|  332|Homo sapiens hASNA-I protein.
          Length = 332

 Score =  238 bits (583), Expect(2) = 3e-68
 Identities = 111/150 (74%), Positives = 135/150 (90%)
 Frame = +3

Query: 264 AVQLSKVRESVLIISTDPAHNISDAFDQKFSKVPTKVKGFDNLFAMEIDPNVGLTELPEE 443
           AVQLSK RESVLIISTDPAHNISDAFDQKFSKVPTKVKG+DNLFAMEIDP++G+ ++P+E
Sbjct: 42  AVQLSKGRESVLIISTDPAHNISDAFDQKFSKVPTKVKGYDNLFAMEIDPSLGVADVPDE 101

Query: 444 YFEGESEAMRLDKGVMQEIVGAFPGIDEAMSYAEVMKLVKGMNFSAVVFDTAPTGHTLRL 623
           +FE E   + + K +MQE + AFPGIDEAMSYAEVM+LVKGMNFS VVFDTAPTGHTLRL
Sbjct: 102 FFE-EDNMLSMGKKMMQEAMSAFPGIDEAMSYAEVMRLVKGMNFSVVVFDTAPTGHTLRL 160

Query: 624 LSFPQVVERGLGKLMRLKSKVXPFINQIAS 713
           L+FP +VERGLG+LM++K+++ PFI+Q+ +
Sbjct: 161 LNFPTIVERGLGRLMQIKNQISPFISQMCN 190



 Score = 40.7 bits (91), Expect(2) = 3e-68
 Identities = 15/22 (68%), Positives = 20/22 (90%)
 Frame = +3

Query: 78  DFEPLEPSLKNVIDQKSLRWIF 143
           D EPLEP+L N+I+Q+SL+WIF
Sbjct: 4   DVEPLEPTLSNIIEQRSLKWIF 25


>U41221-1|AAA82080.1|  887|Homo sapiens hMSH2 protein.
          Length = 887

 Score = 30.7 bits (66), Expect = 5.4
 Identities = 24/91 (26%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
 Frame = +3

Query: 414 NVGLTELPEEYFEGESEAMRLDKGVMQEIVGAFPGIDEAM-SYAEVMKLVKGMNFSAVVF 590
           N  LT L EEY + ++E       +++EIV    G  E M +  +V+  +  +   A V 
Sbjct: 553 NSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAHVS 612

Query: 591 DTAPTGHTLRLLSFPQVVERGLGKLMRLKSK 683
           + AP  +       P ++E+G G+++   S+
Sbjct: 613 NGAPVPYVR-----PAILEKGQGRIILKASR 638


>U04045-1|AAA61870.1|  934|Homo sapiens hMSH2 protein.
          Length = 934

 Score = 30.7 bits (66), Expect = 5.4
 Identities = 24/91 (26%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
 Frame = +3

Query: 414 NVGLTELPEEYFEGESEAMRLDKGVMQEIVGAFPGIDEAM-SYAEVMKLVKGMNFSAVVF 590
           N  LT L EEY + ++E       +++EIV    G  E M +  +V+  +  +   A V 
Sbjct: 553 NSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAHVS 612

Query: 591 DTAPTGHTLRLLSFPQVVERGLGKLMRLKSK 683
           + AP  +       P ++E+G G+++   S+
Sbjct: 613 NGAPVPYVR-----PAILEKGQGRIILKASR 638


>U03911-1|AAA18643.1|  934|Homo sapiens hMSH2 protein.
          Length = 934

 Score = 30.7 bits (66), Expect = 5.4
 Identities = 24/91 (26%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
 Frame = +3

Query: 414 NVGLTELPEEYFEGESEAMRLDKGVMQEIVGAFPGIDEAM-SYAEVMKLVKGMNFSAVVF 590
           N  LT L EEY + ++E       +++EIV    G  E M +  +V+  +  +   A V 
Sbjct: 553 NSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAHVS 612

Query: 591 DTAPTGHTLRLLSFPQVVERGLGKLMRLKSK 683
           + AP  +       P ++E+G G+++   S+
Sbjct: 613 NGAPVPYVR-----PAILEKGQGRIILKASR 638


>L47583-1|AAB59564.1|  934|Homo sapiens DNA mismatch repair protein
           protein.
          Length = 934

 Score = 30.7 bits (66), Expect = 5.4
 Identities = 24/91 (26%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
 Frame = +3

Query: 414 NVGLTELPEEYFEGESEAMRLDKGVMQEIVGAFPGIDEAM-SYAEVMKLVKGMNFSAVVF 590
           N  LT L EEY + ++E       +++EIV    G  E M +  +V+  +  +   A V 
Sbjct: 553 NSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAHVS 612

Query: 591 DTAPTGHTLRLLSFPQVVERGLGKLMRLKSK 683
           + AP  +       P ++E+G G+++   S+
Sbjct: 613 NGAPVPYVR-----PAILEKGQGRIILKASR 638


>L47582-1|AAB59565.1|  934|Homo sapiens DNA mismatch repair protein
           protein.
          Length = 934

 Score = 30.7 bits (66), Expect = 5.4
 Identities = 24/91 (26%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
 Frame = +3

Query: 414 NVGLTELPEEYFEGESEAMRLDKGVMQEIVGAFPGIDEAM-SYAEVMKLVKGMNFSAVVF 590
           N  LT L EEY + ++E       +++EIV    G  E M +  +V+  +  +   A V 
Sbjct: 553 NSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAHVS 612

Query: 591 DTAPTGHTLRLLSFPQVVERGLGKLMRLKSK 683
           + AP  +       P ++E+G G+++   S+
Sbjct: 613 NGAPVPYVR-----PAILEKGQGRIILKASR 638


>L47581-1|AAA76858.1|  934|Homo sapiens DNA mismatch repair protein
           protein.
          Length = 934

 Score = 30.7 bits (66), Expect = 5.4
 Identities = 24/91 (26%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
 Frame = +3

Query: 414 NVGLTELPEEYFEGESEAMRLDKGVMQEIVGAFPGIDEAM-SYAEVMKLVKGMNFSAVVF 590
           N  LT L EEY + ++E       +++EIV    G  E M +  +V+  +  +   A V 
Sbjct: 553 NSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAHVS 612

Query: 591 DTAPTGHTLRLLSFPQVVERGLGKLMRLKSK 683
           + AP  +       P ++E+G G+++   S+
Sbjct: 613 NGAPVPYVR-----PAILEKGQGRIILKASR 638


>L47580-1|AAB59572.1|  810|Homo sapiens MSH2 protein.
          Length = 810

 Score = 30.7 bits (66), Expect = 5.4
 Identities = 24/91 (26%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
 Frame = +3

Query: 414 NVGLTELPEEYFEGESEAMRLDKGVMQEIVGAFPGIDEAM-SYAEVMKLVKGMNFSAVVF 590
           N  LT L EEY + ++E       +++EIV    G  E M +  +V+  +  +   A V 
Sbjct: 553 NSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAHVS 612

Query: 591 DTAPTGHTLRLLSFPQVVERGLGKLMRLKSK 683
           + AP  +       P ++E+G G+++   S+
Sbjct: 613 NGAPVPYVR-----PAILEKGQGRIILKASR 638


>BC021566-1|AAH21566.1|  934|Homo sapiens mutS homolog 2, colon
           cancer, nonpolyposis type 1 (E. coli) protein.
          Length = 934

 Score = 30.7 bits (66), Expect = 5.4
 Identities = 24/91 (26%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
 Frame = +3

Query: 414 NVGLTELPEEYFEGESEAMRLDKGVMQEIVGAFPGIDEAM-SYAEVMKLVKGMNFSAVVF 590
           N  LT L EEY + ++E       +++EIV    G  E M +  +V+  +  +   A V 
Sbjct: 553 NSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAHVS 612

Query: 591 DTAPTGHTLRLLSFPQVVERGLGKLMRLKSK 683
           + AP  +       P ++E+G G+++   S+
Sbjct: 613 NGAPVPYVR-----PAILEKGQGRIILKASR 638


>AY601851-1|AAS99351.1|  934|Homo sapiens mutS homolog 2, colon
           cancer, nonpolyposis type 1 (E. coli) protein.
          Length = 934

 Score = 30.7 bits (66), Expect = 5.4
 Identities = 24/91 (26%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
 Frame = +3

Query: 414 NVGLTELPEEYFEGESEAMRLDKGVMQEIVGAFPGIDEAM-SYAEVMKLVKGMNFSAVVF 590
           N  LT L EEY + ++E       +++EIV    G  E M +  +V+  +  +   A V 
Sbjct: 553 NSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAHVS 612

Query: 591 DTAPTGHTLRLLSFPQVVERGLGKLMRLKSK 683
           + AP  +       P ++E+G G+++   S+
Sbjct: 613 NGAPVPYVR-----PAILEKGQGRIILKASR 638


>AK222860-1|BAD96580.1|  878|Homo sapiens mutS homolog 2 variant
           protein.
          Length = 878

 Score = 30.7 bits (66), Expect = 5.4
 Identities = 24/91 (26%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
 Frame = +3

Query: 414 NVGLTELPEEYFEGESEAMRLDKGVMQEIVGAFPGIDEAM-SYAEVMKLVKGMNFSAVVF 590
           N  LT L EEY + ++E       +++EIV    G  E M +  +V+  +  +   A V 
Sbjct: 553 NSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAHVS 612

Query: 591 DTAPTGHTLRLLSFPQVVERGLGKLMRLKSK 683
           + AP  +       P ++E+G G+++   S+
Sbjct: 613 NGAPVPYVR-----PAILEKGQGRIILKASR 638


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 85,343,785
Number of Sequences: 237096
Number of extensions: 1538006
Number of successful extensions: 3666
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 3584
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3661
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8343197486
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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