BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= NRPG0109 (698 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q4S0T0 Cluster: Chromosome undetermined SCAF14779, whol... 202 9e-51 UniRef50_Q9GKX2 Cluster: Dehydrogenase/reductase SDR family memb... 196 3e-49 UniRef50_Q8WNV7 Cluster: Dehydrogenase/reductase SDR family memb... 193 4e-48 UniRef50_Q9S9W2 Cluster: T1J24.9 protein; n=13; Magnoliophyta|Re... 177 2e-43 UniRef50_Q93790 Cluster: Putative uncharacterized protein; n=2; ... 176 4e-43 UniRef50_O16619 Cluster: Dehydrogenases, short chain protein 13;... 175 9e-43 UniRef50_UPI0000E81F13 Cluster: PREDICTED: similar to MGC108363 ... 173 5e-42 UniRef50_Q13268 Cluster: Dehydrogenase/reductase SDR family memb... 172 6e-42 UniRef50_Q22RY4 Cluster: Oxidoreductase, short chain dehydrogena... 160 3e-38 UniRef50_Q2LE81 Cluster: NADP(H)-dependent retinol dehydrogenase... 88 3e-36 UniRef50_UPI0001555327 Cluster: PREDICTED: similar to NADPH-depe... 151 1e-35 UniRef50_Q0LC46 Cluster: Short-chain dehydrogenase/reductase SDR... 129 6e-29 UniRef50_A2TZ19 Cluster: Oxidoreductase, short-chain dehydrogena... 127 2e-28 UniRef50_Q8F682 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 125 9e-28 UniRef50_Q46NA7 Cluster: Short-chain dehydrogenase/reductase SDR... 121 2e-26 UniRef50_Q89UK7 Cluster: Blr1409 protein; n=7; Proteobacteria|Re... 120 5e-26 UniRef50_A3TVX6 Cluster: Probable dehydrogenase; n=1; Oceanicola... 119 6e-26 UniRef50_A6G1V5 Cluster: Short chain dehydrogenase; n=1; Plesioc... 117 2e-25 UniRef50_Q931B7 Cluster: Putative; n=2; Sinorhizobium|Rep: Putat... 113 3e-24 UniRef50_Q390G9 Cluster: Short-chain dehydrogenase/reductase SDR... 113 3e-24 UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR... 110 4e-23 UniRef50_Q5NW77 Cluster: Short-chain alcohol dehydrogenase; n=2;... 109 6e-23 UniRef50_A3SFH7 Cluster: Oxidoreductase, short-chain dehydrogena... 109 6e-23 UniRef50_Q46UH8 Cluster: Short-chain dehydrogenase/reductase SDR... 107 2e-22 UniRef50_A0NRY8 Cluster: Short-chain dehydrogenase/reductase SDR... 107 2e-22 UniRef50_Q5V0V4 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 107 3e-22 UniRef50_Q8UDS8 Cluster: Short chain dehydrogenase; n=1; Agrobac... 107 3e-22 UniRef50_Q1V2Q8 Cluster: Short chain dehydrogenase; n=2; Candida... 107 3e-22 UniRef50_Q0K243 Cluster: Short chain dehydrogenase; n=3; Cupriav... 107 3e-22 UniRef50_Q023X9 Cluster: Short-chain dehydrogenase/reductase SDR... 107 3e-22 UniRef50_P50162 Cluster: Tropinone reductase 1; n=77; Viridiplan... 107 3e-22 UniRef50_Q8LFZ4 Cluster: Short chain alcohol dehydrogenase-like;... 106 5e-22 UniRef50_Q0FK50 Cluster: Putative uncharacterized protein; n=1; ... 106 6e-22 UniRef50_Q3ACJ4 Cluster: Oxidoreductase, short chain dehydrogena... 105 8e-22 UniRef50_A6F000 Cluster: Putative short-chain dehydrogenase/redu... 105 8e-22 UniRef50_A5V310 Cluster: Short-chain dehydrogenase/reductase SDR... 105 8e-22 UniRef50_Q0IBU9 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 105 1e-21 UniRef50_Q6N3Z1 Cluster: Putative oxidoreductase, short-chain de... 105 1e-21 UniRef50_Q39TG1 Cluster: Short-chain dehydrogenase/reductase SDR... 104 2e-21 UniRef50_Q62E13 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 104 2e-21 UniRef50_Q7W2M6 Cluster: Alcohol dehydrogenase; n=15; cellular o... 103 3e-21 UniRef50_Q1IPD7 Cluster: Short-chain dehydrogenase/reductase SDR... 103 3e-21 UniRef50_Q4IUB1 Cluster: Short-chain dehydrogenase/reductase SDR... 103 4e-21 UniRef50_Q1AYL3 Cluster: Short-chain dehydrogenase/reductase SDR... 103 6e-21 UniRef50_Q0TU60 Cluster: Oxidoreductase, short-chain dehydrogena... 103 6e-21 UniRef50_Q2NIC9 Cluster: Predicted short chain dehydrogenase; n=... 103 6e-21 UniRef50_Q0B254 Cluster: Short-chain dehydrogenase/reductase SDR... 102 1e-20 UniRef50_A3YE37 Cluster: Short-chain dehydrogenase/reductase SDR... 102 1e-20 UniRef50_A1IED1 Cluster: Short-chain dehydrogenase/reductase SDR... 102 1e-20 UniRef50_UPI000051AB3C Cluster: PREDICTED: similar to CG10672-PA... 101 1e-20 UniRef50_Q1IU02 Cluster: Short-chain dehydrogenase/reductase SDR... 101 1e-20 UniRef50_Q0LSE4 Cluster: Short-chain dehydrogenase/reductase SDR... 101 1e-20 UniRef50_UPI00015BAF2E Cluster: short-chain dehydrogenase/reduct... 101 2e-20 UniRef50_A0YD08 Cluster: Short chain dehydrogenase; n=2; Gammapr... 100 3e-20 UniRef50_Q39TG6 Cluster: Short-chain dehydrogenase/reductase SDR... 100 4e-20 UniRef50_Q1D6R5 Cluster: Oxidoreductase, short chain dehydrogena... 100 4e-20 UniRef50_Q8R9W0 Cluster: Dehydrogenases with different specifici... 99 5e-20 UniRef50_A6WB74 Cluster: Short-chain dehydrogenase/reductase SDR... 99 5e-20 UniRef50_A7EQI6 Cluster: Putative uncharacterized protein; n=1; ... 100 7e-20 UniRef50_P55541 Cluster: Uncharacterized short-chain type dehydr... 100 7e-20 UniRef50_Q39ME1 Cluster: Short-chain dehydrogenase/reductase SDR... 99 9e-20 UniRef50_Q39A64 Cluster: Short-chain dehydrogenase/reductase SDR... 99 9e-20 UniRef50_Q0VQZ0 Cluster: Oxidoreductase; n=4; Gammaproteobacteri... 99 9e-20 UniRef50_O61709 Cluster: Putative uncharacterized protein; n=4; ... 99 9e-20 UniRef50_Q08632 Cluster: Short-chain type dehydrogenase/reductas... 99 9e-20 UniRef50_Q1ASB7 Cluster: Short-chain dehydrogenase/reductase SDR... 99 1e-19 UniRef50_A0HIJ6 Cluster: Short-chain dehydrogenase/reductase SDR... 99 1e-19 UniRef50_Q9PCQ2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 98 2e-19 UniRef50_Q89JB0 Cluster: Bll5373 protein; n=4; Bacteria|Rep: Bll... 98 2e-19 UniRef50_Q0RIJ2 Cluster: Putative short chain dehydrogenase/redu... 98 2e-19 UniRef50_A0GVX4 Cluster: Short-chain dehydrogenase/reductase SDR... 98 2e-19 UniRef50_Q21BL9 Cluster: Short-chain dehydrogenase/reductase SDR... 98 2e-19 UniRef50_Q1ARQ7 Cluster: Short-chain dehydrogenase/reductase SDR... 98 2e-19 UniRef50_A1SC90 Cluster: Short-chain dehydrogenase/reductase SDR... 97 3e-19 UniRef50_A0VRR7 Cluster: Short-chain dehydrogenase/reductase SDR... 97 3e-19 UniRef50_Q39TK3 Cluster: Short-chain dehydrogenase/reductase SDR... 97 4e-19 UniRef50_Q2I772 Cluster: PlaU; n=2; Streptomyces|Rep: PlaU - Str... 97 4e-19 UniRef50_Q0SD55 Cluster: Possible short chain oxidoreductase; n=... 97 4e-19 UniRef50_A7AZH2 Cluster: Putative uncharacterized protein; n=1; ... 97 4e-19 UniRef50_A3D6S9 Cluster: Short-chain dehydrogenase/reductase SDR... 97 4e-19 UniRef50_A0X2N7 Cluster: Short-chain dehydrogenase/reductase SDR... 97 4e-19 UniRef50_Q12HD3 Cluster: Short-chain dehydrogenase/reductase SDR... 97 5e-19 UniRef50_Q029B5 Cluster: Short-chain dehydrogenase/reductase SDR... 97 5e-19 UniRef50_A5CFS4 Cluster: Short-chain dehydrogenase/reductase SDR... 96 6e-19 UniRef50_Q8YCL4 Cluster: 3-OXOACYL-(ACYL-CARRIER PROTEIN) REDUCT... 96 6e-19 UniRef50_Q6LH36 Cluster: Hypothetical oxidoreductase, short-chai... 96 6e-19 UniRef50_Q3E0W7 Cluster: NAD-dependent epimerase/dehydratase:Sho... 96 6e-19 UniRef50_Q15TE7 Cluster: Short-chain dehydrogenase/reductase SDR... 96 6e-19 UniRef50_A7DQI5 Cluster: Short-chain dehydrogenase/reductase SDR... 96 6e-19 UniRef50_Q8CUW5 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 96 8e-19 UniRef50_Q2G8A5 Cluster: Short-chain dehydrogenase/reductase SDR... 96 8e-19 UniRef50_A3Z051 Cluster: Short-chain dehydrogenase/reductase SDR... 96 8e-19 UniRef50_Q81RT0 Cluster: Oxidoreductase, short-chain dehydrogena... 95 1e-18 UniRef50_Q3WFP9 Cluster: Short-chain dehydrogenase/reductase SDR... 95 1e-18 UniRef50_Q2VQT1 Cluster: Ketoacyl ACP/CoA reductase-like protein... 95 1e-18 UniRef50_A1SNH6 Cluster: Short-chain dehydrogenase/reductase SDR... 95 1e-18 UniRef50_Q5L166 Cluster: Oxidoreductase; n=8; Bacteria|Rep: Oxid... 95 1e-18 UniRef50_Q126E9 Cluster: Short-chain dehydrogenase/reductase SDR... 95 1e-18 UniRef50_A3WIC9 Cluster: Oxidoreductase, short chain dehydrogena... 95 1e-18 UniRef50_A3I0R2 Cluster: Short chain dehydrogenase; n=2; Bactero... 95 1e-18 UniRef50_A1CGP4 Cluster: Oxidoreductase, short-chain dehydrogena... 95 1e-18 UniRef50_A7DM07 Cluster: Short-chain dehydrogenase/reductase SDR... 95 2e-18 UniRef50_A3ZQM3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 95 2e-18 UniRef50_Q9HLN6 Cluster: Probable glucose 1-dehydrogenase; n=4; ... 95 2e-18 UniRef50_Q987X7 Cluster: Probable short-chain dehydrogenase; n=1... 94 3e-18 UniRef50_Q1GNJ7 Cluster: Short-chain dehydrogenase/reductase SDR... 94 3e-18 UniRef50_A3Q331 Cluster: Short-chain dehydrogenase/reductase SDR... 94 3e-18 UniRef50_A3Q0B5 Cluster: Short-chain dehydrogenase/reductase SDR... 94 3e-18 UniRef50_A3I4P3 Cluster: Short-chain dehydrogenase/reductase SDR... 94 3e-18 UniRef50_A2U8H9 Cluster: Short-chain dehydrogenase/reductase SDR... 94 3e-18 UniRef50_A1ULZ8 Cluster: Short-chain dehydrogenase/reductase SDR... 94 3e-18 UniRef50_Q3EBS2 Cluster: Uncharacterized protein At2g29340.1; n=... 94 3e-18 UniRef50_UPI000045C1E7 Cluster: COG1028: Dehydrogenases with dif... 94 3e-18 UniRef50_Q8F0K8 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 94 3e-18 UniRef50_Q2SJ12 Cluster: Short-chain alcohol dehydrogenase-like ... 94 3e-18 UniRef50_Q1DAW1 Cluster: Oxidoreductase, short-chain dehydrogena... 94 3e-18 UniRef50_Q0SGL9 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 94 3e-18 UniRef50_P94681 Cluster: Toluenesulfonate zinc-independent alcoh... 94 3e-18 UniRef50_A7HFH2 Cluster: Short-chain dehydrogenase/reductase SDR... 94 3e-18 UniRef50_A6CL44 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 94 3e-18 UniRef50_A5FEZ2 Cluster: Short-chain dehydrogenase/reductase SDR... 94 3e-18 UniRef50_A3VK91 Cluster: Putative 3-ketoacyl-CoA reductase; n=1;... 94 3e-18 UniRef50_A1K895 Cluster: Short-chain dehydrogenase family protei... 94 3e-18 UniRef50_A0TW00 Cluster: Short-chain dehydrogenase/reductase SDR... 94 3e-18 UniRef50_A0TVV4 Cluster: Short-chain dehydrogenase/reductase SDR... 94 3e-18 UniRef50_Q9WYS2 Cluster: Oxidoreductase, short chain dehydrogena... 93 4e-18 UniRef50_Q88LI6 Cluster: Oxidoreductase, short chain dehydrogena... 93 4e-18 UniRef50_O34782 Cluster: YvrD protein; n=3; Bacillus|Rep: YvrD p... 93 4e-18 UniRef50_Q1YS84 Cluster: Short-chain dehydrogenase/reductase SDR... 93 4e-18 UniRef50_Q1NCY5 Cluster: Dehydrogenase; n=1; Sphingomonas sp. SK... 93 4e-18 UniRef50_Q97SL2 Cluster: Oxidoreductase, short chain dehydrogena... 93 6e-18 UniRef50_Q89E38 Cluster: Oxidoreductase; n=2; Proteobacteria|Rep... 93 6e-18 UniRef50_Q1VR66 Cluster: 3-oxoacyl-[ACP] reductase; n=1; Psychro... 93 6e-18 UniRef50_Q4A054 Cluster: Uncharacterized oxidoreductase SSP0419;... 93 6e-18 UniRef50_Q9RUC2 Cluster: Oxidoreductase, short-chain dehydrogena... 93 8e-18 UniRef50_Q8EMX3 Cluster: Hypothetical conserved protein; n=1; Oc... 93 8e-18 UniRef50_Q62GI3 Cluster: Oxidoreductase, short-chain dehydrogena... 93 8e-18 UniRef50_Q1ARM4 Cluster: Short-chain dehydrogenase/reductase SDR... 93 8e-18 UniRef50_Q143V4 Cluster: Putative dehydrogenase; n=1; Burkholder... 93 8e-18 UniRef50_Q12AF9 Cluster: Short-chain dehydrogenase/reductase SDR... 93 8e-18 UniRef50_A4Z1Y9 Cluster: Putative short-chain dehydrogenases/red... 93 8e-18 UniRef50_A3XPW3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 93 8e-18 UniRef50_A0JAB3 Cluster: Short-chain dehydrogenase/reductase SDR... 93 8e-18 UniRef50_A3CU09 Cluster: Short-chain dehydrogenase/reductase SDR... 93 8e-18 UniRef50_Q8YNV5 Cluster: Alr4456 protein; n=14; Bacteria|Rep: Al... 92 1e-17 UniRef50_Q826D4 Cluster: Putative 3-oxoacyl-ACP reductase; n=1; ... 92 1e-17 UniRef50_Q7D6M3 Cluster: Oxidoreductase, short-chain dehydrogena... 92 1e-17 UniRef50_Q7D960 Cluster: Oxidoreductase, short-chain dehydrogena... 92 1e-17 UniRef50_Q24N77 Cluster: Putative uncharacterized protein; n=1; ... 92 1e-17 UniRef50_Q1YP85 Cluster: Short chain dehydrogenase; n=1; gamma p... 92 1e-17 UniRef50_Q1IIJ1 Cluster: Short-chain dehydrogenase/reductase SDR... 92 1e-17 UniRef50_Q0SBS0 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 92 1e-17 UniRef50_Q094I4 Cluster: NAD-dependent epimerase/dehydratase; n=... 92 1e-17 UniRef50_A5FRC2 Cluster: Short-chain dehydrogenase/reductase SDR... 92 1e-17 UniRef50_A3HW24 Cluster: Oxidoreductase, short-chain dehydrogena... 92 1e-17 UniRef50_Q97CM7 Cluster: Glucose 1-dehydrogenase; n=6; Archaea|R... 92 1e-17 UniRef50_Q9K636 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 92 1e-17 UniRef50_Q67M07 Cluster: Short-chain dehydrogenase; n=2; Bacteri... 92 1e-17 UniRef50_Q62GY7 Cluster: Oxidoreductase, short-chain dehydrogena... 92 1e-17 UniRef50_Q0SJQ9 Cluster: Probable carveol dehydrogenase; n=1; Rh... 92 1e-17 UniRef50_Q0RCN5 Cluster: Putative dehydrogenase/reductase; n=2; ... 92 1e-17 UniRef50_A6EED4 Cluster: Short-chain dehydrogenase/reductase SDR... 92 1e-17 UniRef50_A5VAV2 Cluster: Short-chain dehydrogenase/reductase SDR... 92 1e-17 UniRef50_A3I6G4 Cluster: Putative 7-alpha-hydroxysteroid dehydro... 92 1e-17 UniRef50_A1ATN3 Cluster: Short-chain dehydrogenase/reductase SDR... 92 1e-17 UniRef50_A0TVU3 Cluster: Short-chain dehydrogenase/reductase SDR... 92 1e-17 UniRef50_Q9F5J1 Cluster: SimJ1; n=5; Actinomycetales|Rep: SimJ1 ... 91 2e-17 UniRef50_Q0LZD3 Cluster: NAD-dependent epimerase/dehydratase:Sho... 91 2e-17 UniRef50_A5VEF9 Cluster: Short-chain dehydrogenase/reductase SDR... 91 2e-17 UniRef50_A5UWJ6 Cluster: Short-chain dehydrogenase/reductase SDR... 91 2e-17 UniRef50_A5CY54 Cluster: Dehydrogenases with different specifici... 91 2e-17 UniRef50_A3Q7E9 Cluster: Short-chain dehydrogenase/reductase SDR... 91 2e-17 UniRef50_A3PW05 Cluster: Short-chain dehydrogenase/reductase SDR... 91 2e-17 UniRef50_A0Z5Q6 Cluster: Short chain dehydrogenase; n=1; marine ... 91 2e-17 UniRef50_Q8TUG0 Cluster: Gluconate 5-dehydrogenase; n=7; cellula... 91 2e-17 UniRef50_O67610 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 91 2e-17 UniRef50_Q62AB7 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=... 91 2e-17 UniRef50_Q1IU03 Cluster: Short-chain dehydrogenase/reductase SDR... 91 2e-17 UniRef50_Q12DF3 Cluster: Short-chain dehydrogenase/reductase SDR... 91 2e-17 UniRef50_Q03906 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 91 2e-17 UniRef50_A5UYE2 Cluster: Short-chain dehydrogenase/reductase SDR... 91 2e-17 UniRef50_A5P1L6 Cluster: Short-chain dehydrogenase/reductase SDR... 91 2e-17 UniRef50_A0YDP4 Cluster: Short chain dehydrogenase; n=1; marine ... 91 2e-17 UniRef50_Q2U8E2 Cluster: Dehydrogenases with different specifici... 91 2e-17 UniRef50_P16544 Cluster: Putative ketoacyl reductase; n=42; Bact... 91 2e-17 UniRef50_Q3W9J0 Cluster: Short-chain dehydrogenase/reductase SDR... 91 3e-17 UniRef50_Q0S4C7 Cluster: Reductase; n=4; Bacteria|Rep: Reductase... 91 3e-17 UniRef50_A6AFC6 Cluster: Oxidoreductase, short chain dehydrogena... 91 3e-17 UniRef50_A4FCN3 Cluster: Short-chain dehydrogenase/reductase SDR... 91 3e-17 UniRef50_Q5NPD9 Cluster: Dehydrogenase; n=1; Zymomonas mobilis|R... 90 4e-17 UniRef50_Q1BBB6 Cluster: Short-chain dehydrogenase/reductase SDR... 90 4e-17 UniRef50_Q182R6 Cluster: Probable short chain dehydrogenase prec... 90 4e-17 UniRef50_A3JBQ4 Cluster: Short-chain dehydrogenase/reductase SDR... 90 4e-17 UniRef50_A1WEP3 Cluster: Short-chain dehydrogenase/reductase SDR... 90 4e-17 UniRef50_Q9LW35 Cluster: Alcohol dehydrogenase-like protein; n=6... 90 4e-17 UniRef50_Q0DM18 Cluster: Os03g0833100 protein; n=5; Oryza sativa... 90 4e-17 UniRef50_Q5V623 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 90 4e-17 UniRef50_A5UJ48 Cluster: Short chain dehydrogenase; n=1; Methano... 90 4e-17 UniRef50_Q8ELN8 Cluster: Glucose 1-dehydrogenase; n=6; cellular ... 90 6e-17 UniRef50_Q7WAF7 Cluster: Putative oxidoreductase; n=3; Bordetell... 90 6e-17 UniRef50_Q39TJ1 Cluster: Short-chain dehydrogenase/reductase SDR... 90 6e-17 UniRef50_Q1VHF4 Cluster: Probable oxidoreductase protein, short-... 90 6e-17 UniRef50_Q1AYK3 Cluster: Short-chain dehydrogenase/reductase SDR... 90 6e-17 UniRef50_Q0LQE1 Cluster: Short-chain dehydrogenase/reductase SDR... 90 6e-17 UniRef50_Q04DL8 Cluster: Acetoin reductase; n=2; Oenococcus oeni... 90 6e-17 UniRef50_A7GTG0 Cluster: Amino acid adenylation domain; n=2; Fir... 90 6e-17 UniRef50_A6UFI1 Cluster: Short-chain dehydrogenase/reductase SDR... 90 6e-17 UniRef50_A5VEF2 Cluster: Short-chain dehydrogenase/reductase SDR... 90 6e-17 UniRef50_A4AAT7 Cluster: Short-chain dehydrogenase/reductase SDR... 90 6e-17 UniRef50_A3JWC2 Cluster: Dehydrogenase; n=1; Rhodobacterales bac... 90 6e-17 UniRef50_A1WLZ9 Cluster: Short-chain dehydrogenase/reductase SDR... 90 6e-17 UniRef50_A1B0V7 Cluster: Short-chain dehydrogenase/reductase SDR... 90 6e-17 UniRef50_A0QXD6 Cluster: L-xylulose reductase; n=2; Actinomyceta... 90 6e-17 UniRef50_A5A7R3 Cluster: 17beta-hydroxysteroid dehydrogenase typ... 90 6e-17 UniRef50_A2QS57 Cluster: Contig An08c0220, complete genome; n=2;... 90 6e-17 UniRef50_Q8EMP9 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 89 7e-17 UniRef50_Q7NCW8 Cluster: Gll2858 protein; n=6; Bacteria|Rep: Gll... 89 7e-17 UniRef50_Q4JXS5 Cluster: Dehydrogenase related to short-chain al... 89 7e-17 UniRef50_Q2CH74 Cluster: Short-chain alcohol dehydrogenase; n=1;... 89 7e-17 UniRef50_Q026E7 Cluster: Short-chain dehydrogenase/reductase SDR... 89 7e-17 UniRef50_A1WNV5 Cluster: Short-chain dehydrogenase/reductase SDR... 89 7e-17 UniRef50_Q8U3B3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 89 7e-17 UniRef50_Q65F37 Cluster: Putative uncharacterized protein; n=1; ... 89 1e-16 UniRef50_Q39YK9 Cluster: Short-chain dehydrogenase/reductase SDR... 89 1e-16 UniRef50_Q9RLV7 Cluster: Diacetyl(Acetoin) reductase; n=4; Lacto... 89 1e-16 UniRef50_Q8GR61 Cluster: Xylitol dehydrogenase; n=2; Gluconobact... 89 1e-16 UniRef50_Q1NH65 Cluster: Dehydrogenase; n=1; Sphingomonas sp. SK... 89 1e-16 UniRef50_Q11C03 Cluster: Short-chain dehydrogenase/reductase SDR... 89 1e-16 UniRef50_A5FBH9 Cluster: Short-chain dehydrogenase/reductase SDR... 89 1e-16 UniRef50_A4AN22 Cluster: Probable glucose 1-dehydrogenase; n=1; ... 89 1e-16 UniRef50_A3IK59 Cluster: Oxidoreductase, short chain dehydrogena... 89 1e-16 UniRef50_Q5BII6 Cluster: RH05486p; n=4; Sophophora|Rep: RH05486p... 89 1e-16 UniRef50_Q9WYG0 Cluster: Uncharacterized oxidoreductase TM_0325;... 89 1e-16 UniRef50_P50198 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 89 1e-16 UniRef50_Q98C97 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 89 1e-16 UniRef50_Q47PW7 Cluster: Short-chain alcohol dehydrogenase; n=1;... 89 1e-16 UniRef50_Q391K0 Cluster: Short-chain dehydrogenase/reductase SDR... 89 1e-16 UniRef50_Q52JK0 Cluster: PhaB; n=16; Bacteria|Rep: PhaB - Bacill... 89 1e-16 UniRef50_Q1AYM3 Cluster: Short-chain dehydrogenase/reductase SDR... 89 1e-16 UniRef50_A5MZ18 Cluster: FabG2; n=2; Clostridia|Rep: FabG2 - Clo... 89 1e-16 UniRef50_A1UPQ1 Cluster: Short-chain dehydrogenase/reductase SDR... 89 1e-16 UniRef50_A0QV78 Cluster: Cyclopentanol dehydrogenase; n=2; Bacte... 89 1e-16 UniRef50_Q56318 Cluster: Uncharacterized oxidoreductase TM_0019;... 89 1e-16 UniRef50_Q05528 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=... 89 1e-16 UniRef50_UPI000023E6B9 Cluster: hypothetical protein FG02829.1; ... 88 2e-16 UniRef50_Q929J7 Cluster: Lin2278 protein; n=14; Bacteria|Rep: Li... 88 2e-16 UniRef50_Q8U9R1 Cluster: Short-chain dehydrogenase; n=3; Rhizobi... 88 2e-16 UniRef50_Q7WM80 Cluster: Probable short chain dehydrogenase; n=1... 88 2e-16 UniRef50_Q5KZB7 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 88 2e-16 UniRef50_Q3WK27 Cluster: Short-chain dehydrogenase/reductase SDR... 88 2e-16 UniRef50_Q1QUQ5 Cluster: Short-chain dehydrogenase/reductase SDR... 88 2e-16 UniRef50_Q1M4Y0 Cluster: Putative short-chain dehydrogenase; n=1... 88 2e-16 UniRef50_Q1GUS2 Cluster: Short-chain dehydrogenase/reductase SDR... 88 2e-16 UniRef50_A7C9E6 Cluster: Short-chain dehydrogenase/reductase SDR... 88 2e-16 UniRef50_A3UA16 Cluster: Acetoin(Diacetyl)reductase; n=6; Bacter... 88 2e-16 UniRef50_Q9N5G3 Cluster: Dehydrogenases, short chain protein 14;... 88 2e-16 UniRef50_Q5KF96 Cluster: Peroxisomal hydratase-dehydrogenase-epi... 88 2e-16 UniRef50_Q9KQH7 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 88 2e-16 UniRef50_Q3M1E6 Cluster: NAD-dependent epimerase/dehydratase pre... 88 2e-16 UniRef50_Q1VPL8 Cluster: Oxidoreductase, short chain dehydrogena... 88 2e-16 UniRef50_Q1LC88 Cluster: Short-chain dehydrogenase/reductase SDR... 88 2e-16 UniRef50_A6T0X0 Cluster: Glucose-1-dehydrogenase, (3-oxoacyl-(Ac... 88 2e-16 UniRef50_A5WE64 Cluster: Short-chain dehydrogenase/reductase SDR... 88 2e-16 UniRef50_A1SJV4 Cluster: Short-chain dehydrogenase/reductase SDR... 88 2e-16 UniRef50_A3H6D0 Cluster: Short-chain dehydrogenase/reductase SDR... 88 2e-16 UniRef50_Q9RH24 Cluster: Putative uncharacterized protein; n=1; ... 87 3e-16 UniRef50_Q3MGE9 Cluster: Short-chain dehydrogenase/reductase SDR... 87 3e-16 UniRef50_Q13GE7 Cluster: Putative short-chain dehydrogenase/redu... 87 3e-16 UniRef50_Q11G59 Cluster: Short-chain dehydrogenase/reductase SDR... 87 3e-16 UniRef50_A7HBZ0 Cluster: Short-chain dehydrogenase/reductase SDR... 87 3e-16 UniRef50_A1TC76 Cluster: Short-chain dehydrogenase/reductase SDR... 87 3e-16 UniRef50_A0YDQ1 Cluster: Short chain dehydrogenase; n=1; marine ... 87 3e-16 UniRef50_Q64BR1 Cluster: 3-oxoacyl-acyl carrier protein reductas... 87 3e-16 UniRef50_P14802 Cluster: Uncharacterized oxidoreductase yoxD; n=... 87 3e-16 UniRef50_P0A2D1 Cluster: Oxidoreductase ucpA; n=21; Bacteria|Rep... 87 3e-16 UniRef50_Q9L2C9 Cluster: Putative dehydrogenase; n=2; Streptomyc... 87 4e-16 UniRef50_Q93H96 Cluster: Putative oxidoreductase; n=1; Streptomy... 87 4e-16 UniRef50_Q46PX5 Cluster: NAD-dependent epimerase/dehydratase:Sho... 87 4e-16 UniRef50_Q46MD0 Cluster: Short-chain dehydrogenase/reductase SDR... 87 4e-16 UniRef50_Q3WJ90 Cluster: Short-chain dehydrogenase/reductase SDR... 87 4e-16 UniRef50_Q12H60 Cluster: Short-chain dehydrogenase/reductase SDR... 87 4e-16 UniRef50_Q0RV59 Cluster: Probable 3-oxoacyl-[acyl-carrier-protei... 87 4e-16 UniRef50_A6C1B7 Cluster: Putative uncharacterized protein; n=1; ... 87 4e-16 UniRef50_A5VCG8 Cluster: Short-chain dehydrogenase/reductase SDR... 87 4e-16 UniRef50_A1WKP5 Cluster: Short-chain dehydrogenase/reductase SDR... 87 4e-16 UniRef50_A1R350 Cluster: Oxidoreductase, short chain dehydrogena... 87 4e-16 UniRef50_A6SL65 Cluster: Putative uncharacterized protein; n=1; ... 87 4e-16 UniRef50_Q9UY54 Cluster: Short-chain alcohol dehydrogenase, puta... 87 4e-16 UniRef50_UPI000038D860 Cluster: COG1028: Dehydrogenases with dif... 87 5e-16 UniRef50_Q9KA03 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 87 5e-16 UniRef50_Q8KKW9 Cluster: Putative oxidoreductase protein; n=1; R... 87 5e-16 UniRef50_Q3IEM3 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 87 5e-16 UniRef50_Q7CZN0 Cluster: AGR_C_2317p; n=3; Proteobacteria|Rep: A... 87 5e-16 UniRef50_Q1YNT8 Cluster: Oxidoreductase, short chain dehydrogena... 87 5e-16 UniRef50_Q1NH34 Cluster: Putative uncharacterized protein; n=1; ... 87 5e-16 UniRef50_Q1GNJ2 Cluster: Short-chain dehydrogenase/reductase SDR... 87 5e-16 UniRef50_Q1AZ56 Cluster: Short-chain dehydrogenase/reductase SDR... 87 5e-16 UniRef50_Q0RBT2 Cluster: Short-chain dehydrogenase; n=1; Frankia... 87 5e-16 UniRef50_A5UP93 Cluster: Short-chain dehydrogenase/reductase SDR... 87 5e-16 UniRef50_A4FF21 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 87 5e-16 UniRef50_A3VC22 Cluster: Short-chain dehydrogenase/reductase SDR... 87 5e-16 UniRef50_Q4J9S4 Cluster: Glucose 1-dehydrogenase; n=6; Thermopro... 87 5e-16 UniRef50_P76633 Cluster: Uncharacterized oxidoreductase ygcW; n=... 87 5e-16 UniRef50_Q92GE0 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 87 5e-16 UniRef50_Q897E2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 86 7e-16 UniRef50_Q7ND89 Cluster: Gll4347 protein; n=3; Cyanobacteria|Rep... 86 7e-16 UniRef50_Q6NDJ6 Cluster: Putative 3-oxoacyl-(Acyl carrier ptn) r... 86 7e-16 UniRef50_Q3M510 Cluster: Short-chain dehydrogenase/reductase SDR... 86 7e-16 UniRef50_Q9KHD1 Cluster: Putative beta-ketoacyl reductase; n=1; ... 86 7e-16 UniRef50_Q1YNT9 Cluster: Putative 3-ketoacyl-CoA reductase; n=2;... 86 7e-16 UniRef50_Q1LDG6 Cluster: Short-chain dehydrogenase/reductase SDR... 86 7e-16 UniRef50_Q1ARM3 Cluster: Short-chain dehydrogenase/reductase SDR... 86 7e-16 UniRef50_A5UX97 Cluster: Short-chain dehydrogenase/reductase SDR... 86 7e-16 UniRef50_A4AA34 Cluster: Short-chain dehydrogenase/reductase SDR... 86 7e-16 UniRef50_A1WWM8 Cluster: Short-chain dehydrogenase/reductase SDR... 86 7e-16 UniRef50_A1UJQ6 Cluster: Short-chain dehydrogenase/reductase SDR... 86 7e-16 UniRef50_Q8TMH3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 86 7e-16 UniRef50_Q97M39 Cluster: 2 deoxy-D-gluconate 3-dehydrogenase; n=... 86 9e-16 UniRef50_Q8ELC2 Cluster: Oxidoreductase; n=2; Bacillaceae|Rep: O... 86 9e-16 UniRef50_Q7MAW1 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 86 9e-16 UniRef50_Q39DX6 Cluster: Short-chain dehydrogenase/reductase SDR... 86 9e-16 UniRef50_Q7D5G1 Cluster: Oxidoreductase, short-chain dehydrogena... 86 9e-16 UniRef50_Q74T42 Cluster: Gluconate 5-dehydrogenase; n=17; Gammap... 86 9e-16 UniRef50_A7CX22 Cluster: Short-chain dehydrogenase/reductase SDR... 86 9e-16 UniRef50_A4FIJ5 Cluster: Oxidoreductase, short chain dehydrogena... 86 9e-16 UniRef50_A1ULI4 Cluster: Short-chain dehydrogenase/reductase SDR... 86 9e-16 UniRef50_A1R613 Cluster: Oxidoreductase, short chain dehydrogena... 86 9e-16 UniRef50_A0QH10 Cluster: Short-chain dehydrogenase/reductase SDR... 86 9e-16 UniRef50_Q7RV91 Cluster: TETRAHYDROXYNAPHTHALENE REDUCTASE; n=12... 86 9e-16 UniRef50_O29061 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=... 86 9e-16 UniRef50_P16543 Cluster: Granaticin polyketide synthase putative... 86 9e-16 UniRef50_Q3KDE6 Cluster: Short-chain dehydrogenase/reductase SDR... 85 1e-15 UniRef50_Q9S3U5 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 85 1e-15 UniRef50_Q01PN9 Cluster: Short-chain dehydrogenase/reductase SDR... 85 1e-15 UniRef50_A7IEE4 Cluster: Short-chain dehydrogenase/reductase SDR... 85 1e-15 UniRef50_A7A2R8 Cluster: Putative uncharacterized protein; n=1; ... 85 1e-15 UniRef50_A6DLZ1 Cluster: Glucose-1-dehydrogenase; n=1; Lentispha... 85 1e-15 UniRef50_A6CM25 Cluster: Oxidoreductase, short chain dehydrogena... 85 1e-15 UniRef50_A1UGA4 Cluster: Short-chain dehydrogenase/reductase SDR... 85 1e-15 UniRef50_A0QZR1 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=... 85 1e-15 UniRef50_Q1EPL7 Cluster: Putative uncharacterized protein; n=6; ... 85 1e-15 UniRef50_Q3IRP1 Cluster: Probable dehydrogenase/ reductase 11; n... 85 1e-15 UniRef50_Q396Q4 Cluster: Short-chain dehydrogenase/reductase SDR... 85 2e-15 UniRef50_Q01TL3 Cluster: Short-chain dehydrogenase/reductase SDR... 85 2e-15 UniRef50_A0YDM1 Cluster: Putative 3-ketoacyl-CoA reductase; n=3;... 85 2e-15 UniRef50_A0GP81 Cluster: Short-chain dehydrogenase/reductase SDR... 85 2e-15 UniRef50_Q5BLE6 Cluster: Zgc:113054; n=8; Euteleostomi|Rep: Zgc:... 85 2e-15 UniRef50_Q7WNC7 Cluster: Probable short chain dehydrogenase; n=1... 85 2e-15 UniRef50_Q7NFL8 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 85 2e-15 UniRef50_Q6D4I9 Cluster: 2-keto-3-deoxygluconate oxidoreductase;... 85 2e-15 UniRef50_Q47QE8 Cluster: Probable short-chain type dehydrogenase... 85 2e-15 UniRef50_Q2S4K7 Cluster: Oxidoreductase, short chain dehydrogena... 85 2e-15 UniRef50_Q2CEL1 Cluster: Short chain dehydrogenase; n=1; Oceanic... 85 2e-15 UniRef50_Q28S70 Cluster: Twin-arginine translocation pathway sig... 85 2e-15 UniRef50_Q1NH63 Cluster: Dehydrogenase; n=1; Sphingomonas sp. SK... 85 2e-15 UniRef50_Q1MNW8 Cluster: Dehydrogenases with different specifici... 85 2e-15 UniRef50_Q0RGH3 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=... 85 2e-15 UniRef50_Q0AVP7 Cluster: Short-chain dehydrogenase/reductase SDR... 85 2e-15 UniRef50_Q01XW0 Cluster: Short-chain dehydrogenase/reductase SDR... 85 2e-15 UniRef50_A4T9G9 Cluster: Short-chain dehydrogenase/reductase SDR... 85 2e-15 UniRef50_A1W2L0 Cluster: Short-chain dehydrogenase/reductase SDR... 85 2e-15 UniRef50_Q98H65 Cluster: Short chain dehydrogenase or 3-ketoacyl... 84 3e-15 UniRef50_Q7NLK9 Cluster: Glucose 1-dehydrogenase; n=18; Bacteria... 84 3e-15 UniRef50_Q9EX74 Cluster: SDR-like enzyme; n=1; Rhodococcus eryth... 84 3e-15 UniRef50_Q6JHM5 Cluster: Putative oxidoreductase, short chain de... 84 3e-15 UniRef50_Q3VYE5 Cluster: Short-chain dehydrogenase/reductase SDR... 84 3e-15 UniRef50_Q03U43 Cluster: Short-chain alcohol dehydrogenase; n=4;... 84 3e-15 UniRef50_A6W2Y5 Cluster: Short-chain dehydrogenase/reductase SDR... 84 3e-15 UniRef50_A6EZZ8 Cluster: Short chain dehydrogenase; n=1; Marinob... 84 3e-15 UniRef50_A1G626 Cluster: Short-chain dehydrogenase/reductase SDR... 84 3e-15 UniRef50_A0QDR7 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 84 3e-15 UniRef50_A0J1E4 Cluster: Short-chain dehydrogenase/reductase SDR... 84 3e-15 UniRef50_Q9EWT4 Cluster: Putative oxidoreductase; n=2; Streptomy... 84 4e-15 UniRef50_Q9A326 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=... 84 4e-15 UniRef50_Q883G7 Cluster: Oxidoreductase, short chain dehydrogena... 84 4e-15 UniRef50_Q7VV50 Cluster: Probable short chain dehydrogenase; n=1... 84 4e-15 UniRef50_Q39MU4 Cluster: Short-chain dehydrogenase/reductase SDR... 84 4e-15 UniRef50_Q2Y990 Cluster: Short-chain dehydrogenase/reductase SDR... 84 4e-15 UniRef50_Q3WC70 Cluster: Short-chain dehydrogenase/reductase SDR... 84 4e-15 UniRef50_Q1YP86 Cluster: Oxidoreductase; n=2; unclassified Gamma... 84 4e-15 UniRef50_Q1PVP3 Cluster: Similar to 3-oxoacyl-[acyl carrier prot... 84 4e-15 UniRef50_Q1NA92 Cluster: Gluconate 5-dehydrogenase; n=1; Sphingo... 84 4e-15 UniRef50_Q1GUT4 Cluster: Short-chain dehydrogenase/reductase SDR... 84 4e-15 UniRef50_Q160J4 Cluster: Oxidoreductase, putative; n=2; Alphapro... 84 4e-15 UniRef50_Q143W5 Cluster: Putative dehydrogenase; n=1; Burkholder... 84 4e-15 UniRef50_Q11BT8 Cluster: Short-chain dehydrogenase/reductase SDR... 84 4e-15 UniRef50_A5V545 Cluster: Short-chain dehydrogenase/reductase SDR... 84 4e-15 UniRef50_A4SZ40 Cluster: Short-chain dehydrogenase/reductase SDR... 84 4e-15 UniRef50_A1BEI7 Cluster: Short-chain dehydrogenase/reductase SDR... 84 4e-15 UniRef50_P50200 Cluster: NADP-dependent 7-alpha-hydroxysteroid d... 84 4e-15 UniRef50_Q88LH9 Cluster: Oxidoreductase, short chain dehydrogena... 64 4e-15 UniRef50_Q93HC0 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 83 5e-15 UniRef50_Q8FV67 Cluster: 2-deoxy-d-gluconate 3-dehydrogenase, pu... 83 5e-15 UniRef50_Q8EXX5 Cluster: 3-ketoacyl-acyl carrier protein reducta... 83 5e-15 UniRef50_Q5NRE0 Cluster: Dehydrogenase; n=67; Bacteria|Rep: Dehy... 83 5e-15 UniRef50_Q39TR6 Cluster: Short-chain dehydrogenase/reductase SDR... 83 5e-15 UniRef50_Q2K0D6 Cluster: Probable oxidoreductase protein, dehydr... 83 5e-15 UniRef50_Q2G4C1 Cluster: Short-chain dehydrogenase/reductase SDR... 83 5e-15 UniRef50_Q6W1J2 Cluster: Putative uncharacterized protein; n=1; ... 83 5e-15 UniRef50_Q3W8G5 Cluster: Short-chain dehydrogenase/reductase SDR... 83 5e-15 UniRef50_Q0LUS2 Cluster: Short-chain dehydrogenase/reductase SDR... 83 5e-15 UniRef50_A4M3J4 Cluster: Short-chain dehydrogenase/reductase SDR... 83 5e-15 UniRef50_A0HM20 Cluster: Short-chain dehydrogenase/reductase SDR... 83 5e-15 UniRef50_A0G4K1 Cluster: Short-chain dehydrogenase/reductase SDR... 83 5e-15 UniRef50_Q88ZY4 Cluster: Short-chain dehydrogenase/oxidoreductas... 83 6e-15 UniRef50_Q2JDM5 Cluster: Short-chain dehydrogenase/reductase SDR... 83 6e-15 UniRef50_Q83ZE7 Cluster: Short-chain dehydrogenase/redutase; n=1... 83 6e-15 UniRef50_Q1GNJ8 Cluster: Short-chain dehydrogenase/reductase SDR... 83 6e-15 UniRef50_Q1FP38 Cluster: Short-chain dehydrogenase/reductase SDR... 83 6e-15 UniRef50_Q1CYK0 Cluster: Putative 3-oxoacyl-(Acyl-carrier-protei... 83 6e-15 UniRef50_Q142X0 Cluster: Short-chain dehydrogenase/reductase SDR... 83 6e-15 UniRef50_Q0SU93 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 83 6e-15 UniRef50_O33454 Cluster: P-cumic alcohol dehydrogenase; n=3; Pro... 83 6e-15 UniRef50_A7U537 Cluster: Short-chain dehydrogenase/reductase; n=... 83 6e-15 UniRef50_A6W2Z2 Cluster: Short-chain dehydrogenase/reductase SDR... 83 6e-15 UniRef50_A5V384 Cluster: Short-chain dehydrogenase/reductase SDR... 83 6e-15 UniRef50_A5V339 Cluster: Short-chain dehydrogenase/reductase SDR... 83 6e-15 UniRef50_A7D4R4 Cluster: Short-chain dehydrogenase/reductase SDR... 83 6e-15 UniRef50_Q9ABX6 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 83 8e-15 UniRef50_Q988B7 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 83 8e-15 UniRef50_P71079 Cluster: Unidentfied dehydrogenase; n=23; Bacill... 83 8e-15 UniRef50_Q3W9H8 Cluster: Short-chain dehydrogenase/reductase SDR... 83 8e-15 UniRef50_Q0RV77 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 83 8e-15 UniRef50_Q0RTV1 Cluster: Short-chain dehydrogenase, SDR family; ... 83 8e-15 UniRef50_A6WAY7 Cluster: Short-chain dehydrogenase/reductase SDR... 83 8e-15 UniRef50_A5VBG4 Cluster: Short-chain dehydrogenase/reductase SDR... 83 8e-15 UniRef50_A5CSQ5 Cluster: Short chain dehydrogenase/oxidoreductas... 83 8e-15 UniRef50_A4FED8 Cluster: Short-chain dehydrogenase/reductase SDR... 83 8e-15 UniRef50_A3ZNA3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 83 8e-15 UniRef50_A3KJN1 Cluster: Putative 3-oxoacyl-acyl-carrier protein... 83 8e-15 UniRef50_A3I573 Cluster: Short chain dehydrogenase; n=2; Bacillu... 83 8e-15 UniRef50_A0Z7K1 Cluster: Short-chain dehydrogenase/reductase SDR... 83 8e-15 UniRef50_A0Z4N7 Cluster: Short chain dehydrogenase; n=2; Bacteri... 83 8e-15 UniRef50_A4QV37 Cluster: Putative uncharacterized protein; n=1; ... 83 8e-15 UniRef50_Q6FBA5 Cluster: Putative oxidoreductase, short-chain de... 82 1e-14 UniRef50_Q5P5I4 Cluster: (S)-1-Phenylethanol dehydrogenase; n=1;... 82 1e-14 UniRef50_Q3KCL1 Cluster: Short-chain dehydrogenase/reductase SDR... 82 1e-14 UniRef50_Q396I4 Cluster: Short-chain dehydrogenase/reductase SDR... 82 1e-14 UniRef50_Q393N0 Cluster: Short-chain dehydrogenase/reductase SDR... 82 1e-14 UniRef50_Q9XDF5 Cluster: Putative ketoacyl reductase; n=1; Strep... 82 1e-14 UniRef50_Q1YII7 Cluster: Possible short-chain dehydrogenase/redu... 82 1e-14 UniRef50_Q1B6I2 Cluster: Short-chain dehydrogenase/reductase SDR... 82 1e-14 UniRef50_A7IFR8 Cluster: Short-chain dehydrogenase/reductase SDR... 82 1e-14 UniRef50_A0R386 Cluster: Dehydrogenase/reductase SDR family prot... 82 1e-14 UniRef50_A1CDI4 Cluster: Short chain dehydrogenase/reductase fam... 82 1e-14 UniRef50_P33368 Cluster: Uncharacterized oxidoreductase yohF; n=... 82 1e-14 UniRef50_Q98BT6 Cluster: Mll5433 protein; n=40; Bacteria|Rep: Ml... 82 1e-14 UniRef50_Q89UV5 Cluster: Dehydrogenase; n=12; Alphaproteobacteri... 82 1e-14 UniRef50_Q89P10 Cluster: Oxidoreductase; n=1; Bradyrhizobium jap... 82 1e-14 UniRef50_Q89HU1 Cluster: Bll5898 protein; n=36; Proteobacteria|R... 82 1e-14 UniRef50_Q5WBW4 Cluster: Oxidoreductase; n=1; Bacillus clausii K... 82 1e-14 UniRef50_Q5LMX2 Cluster: 20-beta-hydroxysteroid dehydrogenase, p... 82 1e-14 UniRef50_Q2RLD2 Cluster: Short-chain dehydrogenase/reductase SDR... 82 1e-14 UniRef50_Q5KRC1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 82 1e-14 UniRef50_Q3WGS3 Cluster: Short-chain dehydrogenase/reductase SDR... 82 1e-14 UniRef50_Q3WAU6 Cluster: Short-chain dehydrogenase/reductase SDR... 82 1e-14 UniRef50_Q2CJE1 Cluster: Short-chain dehydrogenase/reductase SDR... 82 1e-14 UniRef50_Q21D49 Cluster: Short-chain dehydrogenase/reductase SDR... 82 1e-14 UniRef50_Q1U845 Cluster: NAD-dependent epimerase/dehydratase:Sho... 82 1e-14 UniRef50_Q1ITR9 Cluster: Short-chain dehydrogenase/reductase SDR... 82 1e-14 UniRef50_Q0JZY8 Cluster: 3-Oxoacyl-[acyl-carrier-protein] reduct... 82 1e-14 UniRef50_A7NQP2 Cluster: Short-chain dehydrogenase/reductase SDR... 82 1e-14 UniRef50_A7H6A6 Cluster: Short-chain dehydrogenase/reductase SDR... 82 1e-14 UniRef50_A6M088 Cluster: Short-chain dehydrogenase/reductase SDR... 82 1e-14 UniRef50_A3W7Y7 Cluster: Putative uncharacterized protein; n=3; ... 82 1e-14 UniRef50_A3J7V6 Cluster: Short-chain dehydrogenase/reductase SDR... 82 1e-14 UniRef50_A1SP95 Cluster: Short-chain dehydrogenase/reductase SDR... 82 1e-14 UniRef50_A0K1M9 Cluster: Short-chain dehydrogenase/reductase SDR... 82 1e-14 UniRef50_Q5V3M2 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 82 1e-14 UniRef50_Q4J9F2 Cluster: Short chain dehydrogenase; n=1; Sulfolo... 82 1e-14 UniRef50_P50160 Cluster: Sex determination protein tasselseed-2;... 82 1e-14 UniRef50_P80869 Cluster: Glucose 1-dehydrogenase 2; n=39; Bacill... 82 1e-14 UniRef50_Q9A322 Cluster: D-beta-hydroxybutyrate dehydrogenase; n... 81 2e-14 UniRef50_Q930L3 Cluster: Putative; n=2; Sinorhizobium|Rep: Putat... 81 2e-14 UniRef50_Q8YHX9 Cluster: SHORT-CHAIN DEHYDROGENASE; n=10; Bacter... 81 2e-14 UniRef50_Q629N6 Cluster: Putative polyketide synthase; n=11; Bur... 81 2e-14 UniRef50_Q28P30 Cluster: Short-chain dehydrogenase/reductase SDR... 81 2e-14 UniRef50_Q140J4 Cluster: Putative 3-oxoacyl-(Acyl-carrier protei... 81 2e-14 UniRef50_O84991 Cluster: Putative short-chain dehydrogenase/redu... 81 2e-14 UniRef50_A5V309 Cluster: Short-chain dehydrogenase/reductase SDR... 81 2e-14 UniRef50_A4XYR7 Cluster: Short-chain dehydrogenase/reductase SDR... 81 2e-14 UniRef50_A0GHU7 Cluster: Short-chain dehydrogenase/reductase SDR... 81 2e-14 UniRef50_Q16VA4 Cluster: Short-chain dehydrogenase; n=2; Culicid... 81 2e-14 UniRef50_Q8TTL5 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 81 2e-14 UniRef50_Q89NC8 Cluster: Oxidoreductase; n=1; Bradyrhizobium jap... 81 3e-14 UniRef50_Q65SP1 Cluster: FabG protein; n=10; Bacteria|Rep: FabG ... 81 3e-14 UniRef50_Q397Q8 Cluster: Short-chain dehydrogenase/reductase SDR... 81 3e-14 UniRef50_Q3E3J6 Cluster: Short-chain dehydrogenase/reductase SDR... 81 3e-14 UniRef50_Q2CJB6 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 81 3e-14 UniRef50_Q1NHE9 Cluster: Putative short chain dehydrogenase; n=1... 81 3e-14 UniRef50_A6WBU5 Cluster: Short-chain dehydrogenase/reductase SDR... 81 3e-14 UniRef50_A6D230 Cluster: Short-chain dehydrogenase; n=1; Vibrio ... 81 3e-14 UniRef50_A5V1Y0 Cluster: Short-chain dehydrogenase/reductase SDR... 81 3e-14 UniRef50_A3WFK2 Cluster: Glucose dehydrogenase; n=1; Erythrobact... 81 3e-14 UniRef50_A3SDF7 Cluster: Short-chain dehydrogenase/reductase SDR... 81 3e-14 UniRef50_A3PXP3 Cluster: Short-chain dehydrogenase/reductase SDR... 81 3e-14 UniRef50_A3PQM4 Cluster: Short-chain dehydrogenase/reductase SDR... 81 3e-14 UniRef50_A3K7W9 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=... 81 3e-14 UniRef50_A1SPQ9 Cluster: Short-chain dehydrogenase/reductase SDR... 81 3e-14 UniRef50_Q2UEK6 Cluster: Dehydrogenases with different specifici... 81 3e-14 >UniRef50_Q4S0T0 Cluster: Chromosome undetermined SCAF14779, whole genome shotgun sequence; n=4; Bilateria|Rep: Chromosome undetermined SCAF14779, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 295 Score = 202 bits (492), Expect = 9e-51 Identities = 103/196 (52%), Positives = 130/196 (66%), Gaps = 3/196 (1%) Frame = +1 Query: 118 ANPV---RAIQSTRFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQS 288 +NPV R + + +GKVAIVTAST+GIG A A+ LGS GA VV+ SR+++NV KAV Sbjct: 11 SNPVAGQRNMSQSSLTGKVAIVTASTDGIGLAAAQALGSRGAHVVVSSRRQANVDKAVAL 70 Query: 289 LRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWD 468 LRS+ I V G C+V E R +L + A + GG+DIL LD+ E+VWD Sbjct: 71 LRSQDIQVTGTTCNVGKGEDREKLIQTALDRCGGIDILVSNAAVNPFFGNTLDSTEEVWD 130 Query: 469 KIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKA 648 KI VNVKS++LL K P + KRGGG+I+F+SS+ AYQP + LG Y VSKT LLGLTK Sbjct: 131 KILSVNVKSAFLLTKLVVPHMEKRGGGNIIFVSSVGAYQPMQGLGPYCVSKTALLGLTKV 190 Query: 649 IANETVHENIRVNCVA 696 +A E NIRVNCVA Sbjct: 191 LAPELAQSNIRVNCVA 206 >UniRef50_Q9GKX2 Cluster: Dehydrogenase/reductase SDR family member 4; n=11; Coelomata|Rep: Dehydrogenase/reductase SDR family member 4 - Oryctolagus cuniculus (Rabbit) Length = 260 Score = 196 bits (479), Expect = 3e-49 Identities = 96/181 (53%), Positives = 124/181 (68%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 + KVAIVTAST+GIG AIA+RL +GA VVI SRK+ NV +AV +L++EG++V G VCHV Sbjct: 13 ANKVAIVTASTDGIGLAIARRLAQDGAHVVISSRKQQNVDRAVAALQAEGLSVTGTVCHV 72 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 E R RL A + GG+DIL ++D E+VWDKI D+NVK+ L+ K Sbjct: 73 GKAEDRERLVATALNLHGGIDILVSNAAVNPFFGKLMDVTEEVWDKILDINVKAMALMTK 132 Query: 514 EAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 PE+ KRGGGS+V ++SIAA+ P LG Y VSKT L+GLTK +A E +NIRVNC+ Sbjct: 133 AVVPEMEKRGGGSVVIVASIAAFNPFSGLGPYNVSKTALVGLTKNLALELAAQNIRVNCL 192 Query: 694 A 696 A Sbjct: 193 A 193 >UniRef50_Q8WNV7 Cluster: Dehydrogenase/reductase SDR family member 4; n=9; Eutheria|Rep: Dehydrogenase/reductase SDR family member 4 - Sus scrofa (Pig) Length = 260 Score = 193 bits (470), Expect = 4e-48 Identities = 95/179 (53%), Positives = 120/179 (67%) Frame = +1 Query: 160 KVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVAN 339 KVA+VTAST+GIG AIA+RL +GA VV+ SRK+ NV + V +L+ EG++V G VCHV Sbjct: 15 KVALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQGEGLSVTGTVCHVGK 74 Query: 340 HEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKEA 519 E R RL +A + GGVDIL I+D E+VWDKI VNVK++ L+ K Sbjct: 75 AEDRERLVAMAVNLHGGVDILVSNAAVNPFFGNIIDATEEVWDKILHVNVKATVLMTKAV 134 Query: 520 YPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVA 696 PE+ KRGGGS++ +SS+ AY P LG Y VSKT LLGLTK +A E NIRVNC+A Sbjct: 135 VPEMEKRGGGSVLIVSSVGAYHPFPNLGPYNVSKTALLGLTKNLAVELAPRNIRVNCLA 193 >UniRef50_Q9S9W2 Cluster: T1J24.9 protein; n=13; Magnoliophyta|Rep: T1J24.9 protein - Arabidopsis thaliana (Mouse-ear cress) Length = 254 Score = 177 bits (432), Expect = 2e-43 Identities = 92/183 (50%), Positives = 122/183 (66%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 R GKVAIVTAST+GIG+ I +R G EGASVV+ SRK++NV +AV L+S+GI G+VC Sbjct: 8 RLEGKVAIVTASTQGIGFGITERFGLEGASVVVSSRKQANVDEAVAKLKSKGIDAYGIVC 67 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 HV+N +HRR L E K+G +DI+ IL + E V DK++++NVKSS LL Sbjct: 68 HVSNAQHRRNLVEKTVQKYGKIDIVVCNAAANPSTDPILSSKEAVLDKLWEINVKSSILL 127 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 ++ P L K G S++FI+SIA + P + YGV+KT LLGLTKA+A E + RVN Sbjct: 128 LQDMAPHLEK--GSSVIFITSIAGFSPQGAMAMYGVTKTALLGLTKALAAEMAPDT-RVN 184 Query: 688 CVA 696 VA Sbjct: 185 AVA 187 >UniRef50_Q93790 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 260 Score = 176 bits (429), Expect = 4e-43 Identities = 86/184 (46%), Positives = 128/184 (69%), Gaps = 1/184 (0%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGIT-VEGVV 324 RF GKVAIVTA+T+GIG AIA+RL EGASVVI SR + NV +A++ L+++G+T V G+ Sbjct: 7 RFEGKVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLTKVAGIA 66 Query: 325 CHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWL 504 H+A+ + +++L + KFG ++IL IL+ +QVWDK+F+VNVK+ + Sbjct: 67 GHIASTDDQKKLVDFTLQKFGKINILVNNHGINPAFGHILEVSDQVWDKLFEVNVKAGFQ 126 Query: 505 LAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRV 684 + K +P + K GGG+I+F +S +AY+ + AYGV+KTTL+GLT+A+A +NIRV Sbjct: 127 MTKLVHPHIAKEGGGAIIFNASYSAYKSPPGIAAYGVTKTTLVGLTRALAMGLAKDNIRV 186 Query: 685 NCVA 696 N +A Sbjct: 187 NGIA 190 >UniRef50_O16619 Cluster: Dehydrogenases, short chain protein 13; n=4; Bilateria|Rep: Dehydrogenases, short chain protein 13 - Caenorhabditis elegans Length = 257 Score = 175 bits (426), Expect = 9e-43 Identities = 87/189 (46%), Positives = 120/189 (63%), Gaps = 1/189 (0%) Frame = +1 Query: 133 AIQSTRF-SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGIT 309 A +T+F + +VA+VTAST+GIG+AIAK+LG+ GASVV+CSRK+ NV +AV +LR E I Sbjct: 2 ASPATKFLTDRVALVTASTKGIGFAIAKQLGAAGASVVVCSRKKENVDEAVAALRLENID 61 Query: 310 VEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNV 489 G HV N R +L + +F +DIL ++ + WDK+ D+NV Sbjct: 62 AHGTTAHVGNKSDRTKLIDFTLDRFTKLDILVSNAAVNPHYGDLMKVTDSQWDKLLDLNV 121 Query: 490 KSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVH 669 KS++ L KEA P L G G++VF+SS+A Y P +GAY V KTTL GL+K++A Sbjct: 122 KSAFELTKEAVPHLEASGRGNVVFVSSVAGYSPMNEIGAYSVMKTTLTGLSKSLALNLAR 181 Query: 670 ENIRVNCVA 696 NIRVN +A Sbjct: 182 RNIRVNSIA 190 >UniRef50_UPI0000E81F13 Cluster: PREDICTED: similar to MGC108363 protein; n=2; Gallus gallus|Rep: PREDICTED: similar to MGC108363 protein - Gallus gallus Length = 310 Score = 173 bits (420), Expect = 5e-42 Identities = 81/180 (45%), Positives = 115/180 (63%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVA 336 GKVA+VTA+T+GIG A+A+RLG GA V++ SR++ NV AVQ LR++G+ V GVVCHV Sbjct: 27 GKVAVVTAATDGIGLAVAQRLGEAGARVLLSSRRQPNVDAAVQKLRAQGLEVSGVVCHVG 86 Query: 337 NHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKE 516 + R+ L + A +G +DIL L+ +E W+KIF VNV ++ +L K Sbjct: 87 QPQDRQHLVQTALDTYGAIDILVSNAAVNPVMGSTLEVEESAWEKIFQVNVTAAAMLVKL 146 Query: 517 AYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVA 696 P + KRGGG++V ++S+A + P LG Y VSKT+LLGL +A E +R+N VA Sbjct: 147 VVPHMEKRGGGAVVLVTSVAGFMPFPALGPYSVSKTSLLGLVNVLAPELRARGVRINAVA 206 >UniRef50_Q13268 Cluster: Dehydrogenase/reductase SDR family member 2; n=64; Eumetazoa|Rep: Dehydrogenase/reductase SDR family member 2 - Homo sapiens (Human) Length = 258 Score = 172 bits (419), Expect = 6e-42 Identities = 88/180 (48%), Positives = 113/180 (62%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 + +VA+VT ST GIG+AIA+RL +GA VVI SRK+ NV +A+ L+ EG++V G+VCHV Sbjct: 13 ANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHV 72 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 E R +L A GGVD L L T EQ+WDKI VNVKS LL Sbjct: 73 GKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLS 132 Query: 514 EAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 + P + R G+++ +SSIAAY P LG Y VSKT LLGLT+ +A E ++IRVNCV Sbjct: 133 QLLPYMENR-RGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCV 191 >UniRef50_Q22RY4 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein; n=2; Oligohymenophorea|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein - Tetrahymena thermophila SB210 Length = 255 Score = 160 bits (388), Expect = 3e-38 Identities = 79/183 (43%), Positives = 112/183 (61%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 RF KVAIVTAS+ GIG I+KRL EGA+V+I SR + NV +AV+ +R G EG+VC Sbjct: 8 RFENKVAIVTASSTGIGLDISKRLALEGATVIINSRSQKNVTEAVEMIRQLGGKAEGLVC 67 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 H E R++L + A KFGGVDIL DT EQ DK++++N K L Sbjct: 68 HAGKPEDRQKLLQFAKDKFGGVDILIPNAAVSTFMGAFTDTPEQAMDKMYEINFKGVLFL 127 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 ++A P + R G +++ +SS++ Y+ +G YG++KT +L + K +A E + IRVN Sbjct: 128 VRDALPFMRGRKGANVILVSSLSGYEQENLIGFYGITKTMVLVMNKLLARELQSDGIRVN 187 Query: 688 CVA 696 CVA Sbjct: 188 CVA 190 >UniRef50_Q2LE81 Cluster: NADP(H)-dependent retinol dehydrogenase/reductase B1 isoform; n=14; Eutheria|Rep: NADP(H)-dependent retinol dehydrogenase/reductase B1 isoform - Homo sapiens (Human) Length = 244 Score = 87.8 bits (208), Expect(2) = 3e-36 Identities = 41/73 (56%), Positives = 51/73 (69%) Frame = +1 Query: 478 DVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIAN 657 D+NVK+ L+ K PE+ KRGGGS+V +SSIAA+ P+ Y VSKT LLGLTK +A Sbjct: 105 DINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAI 164 Query: 658 ETVHENIRVNCVA 696 E NIRVNC+A Sbjct: 165 ELAPRNIRVNCLA 177 Score = 87.4 bits (207), Expect(2) = 3e-36 Identities = 43/75 (57%), Positives = 57/75 (76%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 + KVA+VTAST+GIG+AIA+RL +GA VV+ SRK+ NV +AV +L+ EG++V G VCHV Sbjct: 31 ANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHV 90 Query: 334 ANHEHRRRLFEVATS 378 E R RL VAT+ Sbjct: 91 GKAEDRERL--VATT 103 >UniRef50_UPI0001555327 Cluster: PREDICTED: similar to NADPH-dependent retinol dehydrogenase/reductase, partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to NADPH-dependent retinol dehydrogenase/reductase, partial - Ornithorhynchus anatinus Length = 496 Score = 151 bits (367), Expect = 1e-35 Identities = 72/148 (48%), Positives = 99/148 (66%) Frame = +1 Query: 190 GIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEV 369 GIG A+A+RLG +GA VV+ SRK+ NV +AV +L++EG++V G VCHV E R RL Sbjct: 29 GIGLAVARRLGRDGAHVVLSSRKQKNVDRAVAALQAEGLSVSGTVCHVGKAEDRERLVAT 88 Query: 370 ATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGG 549 A ++GG+DIL +LD E+VWDKI D+NVK++ LL K PE+ KRGGG Sbjct: 89 ALERYGGIDILVSNAAVNPFFGNLLDASEEVWDKILDINVKATVLLVKAVVPEMEKRGGG 148 Query: 550 SIVFISSIAAYQPTEPLGAYGVSKTTLL 633 S++ +SSIAA+ P PL ++ T+LL Sbjct: 149 SVIIVSSIAAFSPL-PLFSFSPFSTSLL 175 >UniRef50_Q0LC46 Cluster: Short-chain dehydrogenase/reductase SDR; n=9; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Herpetosiphon aurantiacus ATCC 23779 Length = 257 Score = 129 bits (312), Expect = 6e-29 Identities = 64/181 (35%), Positives = 100/181 (55%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 SGKVAIVT ++ GIG AIA+ GA VV+C+RK ++ S+ G T + CH Sbjct: 7 SGKVAIVTGASRGIGEAIAQHFAQAGAKVVVCARKLESLQTVADSINQAGGTALAMACHT 66 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 E + + +++G +DI+ +L++D WDK ++VNVK + L + Sbjct: 67 GKPEQVQAVVAQTLAEWGRIDIVVNNAATNPHFGPLLNSDASQWDKTYEVNVKGYFWLIQ 126 Query: 514 EAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 A + +GGGSI+ ++S+A QP +G Y +SK ++ +TK +A E NIRVN + Sbjct: 127 AAAEAMQAQGGGSIINVASVAGLQPATAMGIYSISKAAVIAMTKQLAQELGPMNIRVNAL 186 Query: 694 A 696 A Sbjct: 187 A 187 >UniRef50_A2TZ19 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family protein; n=3; Bacteroidetes|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family protein - Polaribacter dokdonensis MED152 Length = 257 Score = 127 bits (307), Expect = 2e-28 Identities = 64/180 (35%), Positives = 94/180 (52%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 SGKVA++T S++GIG AIAK L +GA VVI SR + + + + +G+ G+ CH+ Sbjct: 10 SGKVAVITGSSKGIGKAIAKGLAEQGAQVVISSRNQEACDEVAKEFKEQGLDTIGIACHI 69 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 + R+ L + FG +DIL I + +++DKI DVNVK+ W L+ Sbjct: 70 GKEDQRKNLVDKTIESFGRIDILVNNAAINPVFGPIEEVSPEIFDKIMDVNVKAPWSLSN 129 Query: 514 EAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 P GSI+ I+S+ A P LG Y SK +L LTK A E ++ N + Sbjct: 130 LVLPHFQTNKNGSIINIASVEALTPGLGLGIYSTSKAAILMLTKNQAKEWGKYGVKANAI 189 >UniRef50_Q8F682 Cluster: 3-oxoacyl-(Acyl carrier protein) reductase; n=4; Leptospira|Rep: 3-oxoacyl-(Acyl carrier protein) reductase - Leptospira interrogans Length = 256 Score = 125 bits (302), Expect = 9e-28 Identities = 65/178 (36%), Positives = 96/178 (53%) Frame = +1 Query: 160 KVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVAN 339 KVAIVT + GIG A+ K S+G VV C R+ K +R+EG V VVC V + Sbjct: 8 KVAIVTGGSTGIGKAVVKEFVSKGVKVVFCGRRLEEGKKLESEIRAEGGDVYFVVCDVTS 67 Query: 340 HEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKEA 519 E +++ + A KFG +D + + E VWDK+ +VN+K +WL K Sbjct: 68 GEQVKKVVDAALEKFGRLDFGINNAGIMGLNHLLHEYPEDVWDKVVNVNLKGTWLSMKYQ 127 Query: 520 YPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 PE++K GGG +V +SSI+ + Y +K ++GLTK+ A E +NIR+N + Sbjct: 128 IPEMIKMGGGVVVNVSSISGINGVVGINPYAAAKHGVVGLTKSAALEYAKKNIRINAI 185 >UniRef50_Q46NA7 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Ralstonia eutropha JMP134|Rep: Short-chain dehydrogenase/reductase SDR - Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) Length = 255 Score = 121 bits (291), Expect = 2e-26 Identities = 65/181 (35%), Positives = 102/181 (56%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 +G+VA+VT ST G+G AIA+ L GA VV+ S +S+ A L SEG V+G+ C + Sbjct: 9 TGRVAVVTGSTSGMGLAIARGLAQCGAQVVVSSHLQSDTDSAASLLASEGFDVKGIPCDI 68 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 N ++ + E + FG VDI+ I +TD + D + V+++ +L + Sbjct: 69 TNLDNVKNFSEESKRAFGHVDIVVCHAAGPVPVGPIAETDIDLLDSLLLTTVRNNLVLIR 128 Query: 514 EAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 + PE+ +R GS++ SSIA+ + + LGAYG +K L G+ ++IA E NIR N + Sbjct: 129 QFLPEMAERRYGSVLMTSSIASERASPALGAYGAAKAALNGVVRSIAAEWGQWNIRANAL 188 Query: 694 A 696 A Sbjct: 189 A 189 >UniRef50_Q89UK7 Cluster: Blr1409 protein; n=7; Proteobacteria|Rep: Blr1409 protein - Bradyrhizobium japonicum Length = 266 Score = 120 bits (288), Expect = 5e-26 Identities = 64/181 (35%), Positives = 99/181 (54%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 +GKVAIVT S+ GIG + A+ L GA VV+ SRK + + + G + C++ Sbjct: 18 TGKVAIVTGSSRGIGRSSAELLARLGAKVVVSSRKADACKEVADGINAAGGDAIVIPCNI 77 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 A L AT+ +G +DIL +LD ++ +DKI NVKS+ L+ Sbjct: 78 ARKAEVEALIAGATTHYGKIDILVCNAAVNPYYGPLLDITDEAFDKIMGSNVKSNIWLSA 137 Query: 514 EAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 A P++ +RG GS++ ISSI + + +GAYG+SK L +++A E + +RVNC+ Sbjct: 138 LAIPQMAERGNGSVIIISSIGGLRGSTVIGAYGISKAADFALCRSLAGEWGPKGVRVNCI 197 Query: 694 A 696 A Sbjct: 198 A 198 >UniRef50_A3TVX6 Cluster: Probable dehydrogenase; n=1; Oceanicola batsensis HTCC2597|Rep: Probable dehydrogenase - Oceanicola batsensis HTCC2597 Length = 254 Score = 119 bits (287), Expect = 6e-26 Identities = 61/182 (33%), Positives = 98/182 (53%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 R KV ++T S+ GIG A+A+ GA VV+ SRK +++R +G V C Sbjct: 6 RLKDKVVVITGSSRGIGRAMAEMFAEAGARVVVSSRKREACKPVAEAIREKGGEAIVVPC 65 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 H+ N E + L + ++G +D+L + D D+ V+DK+ NV++ + Sbjct: 66 HIGNPEDLQNLVDTTIREWGRIDVLVPNAAINPVYGPMQDLDDAVFDKMLVTNVRTINTM 125 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 K P + + GGG++V ISS+AA + + LGAYGV+K + +A+A E +NIRVN Sbjct: 126 CKMVLPRMAENGGGAVVIISSVAAIKGSTTLGAYGVTKAADAAVARALALEWGPQNIRVN 185 Query: 688 CV 693 + Sbjct: 186 AI 187 >UniRef50_A6G1V5 Cluster: Short chain dehydrogenase; n=1; Plesiocystis pacifica SIR-1|Rep: Short chain dehydrogenase - Plesiocystis pacifica SIR-1 Length = 267 Score = 117 bits (282), Expect = 2e-25 Identities = 69/193 (35%), Positives = 96/193 (49%), Gaps = 1/193 (0%) Frame = +1 Query: 118 ANPVRAIQSTRFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRS 297 + P A S + KVAIVT + GIG A A L GA VVI SRK + +A +R Sbjct: 2 SEPSSASSSFDLNSKVAIVTGGSRGIGLATATALSRAGAKVVIASRKPEPLEQAAAHIRE 61 Query: 298 E-GITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKI 474 + G V V H + E +R+ FGGVD+L I+ + + WDK Sbjct: 62 QTGGEVLAVPAHTGDDEAVQRVVAKTVEAFGGVDVLVNNAATNPHFGPIMSSQDSHWDKT 121 Query: 475 FDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIA 654 +DVNVK + + K PE+ RGGG I+ I+S+A + +G Y VSK + LT+ +A Sbjct: 122 YDVNVKGYFRMVKACVPEMQTRGGGRIINIASVAGRRVQPGMGVYCVSKAAVCMLTQVLA 181 Query: 655 NETVHENIRVNCV 693 E I VN + Sbjct: 182 VELADAKINVNAL 194 >UniRef50_Q931B7 Cluster: Putative; n=2; Sinorhizobium|Rep: Putative - Rhizobium meliloti (Sinorhizobium meliloti) Length = 261 Score = 113 bits (273), Expect = 3e-24 Identities = 66/181 (36%), Positives = 98/181 (54%) Frame = +1 Query: 151 FSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCH 330 F+GK +VT + G+G A A R + G V I + +++V +AV S+ G G V Sbjct: 4 FNGKSIVVTGGSLGMGLACAHRFAAGGGKVTIVANDKASVDEAVTSI---GDNAAGFVGD 60 Query: 331 VANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLA 510 V + + A S+ GGVDIL ++DT ++VWD + D+N+K +L + Sbjct: 61 VRSKADMNAAVQAAVSRHGGVDILACCAGIQRYGT-VVDTADEVWDDVLDINLKGIFLAS 119 Query: 511 KEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNC 690 K A PE+ KRGGG+IV ISS+ AY + AY SK + L +A+A + +NI VN Sbjct: 120 KFAIPEMRKRGGGAIVAISSVQAYASQTGVAAYTASKGAINALVRAMALDHAGDNITVNA 179 Query: 691 V 693 V Sbjct: 180 V 180 >UniRef50_Q390G9 Cluster: Short-chain dehydrogenase/reductase SDR; n=33; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 254 Score = 113 bits (273), Expect = 3e-24 Identities = 62/180 (34%), Positives = 94/180 (52%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 +GK+A+VT ++ GIG IAK L +GA V++ SRK + + + G E + CHV Sbjct: 9 TGKIALVTGASRGIGEEIAKLLAEQGAHVIVSSRKLDDCQAVADEIVAAGGRAEALACHV 68 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 + FE K G +DIL ILDTD ++K DVN++ + ++ Sbjct: 69 GRLDDIAATFEHIRGKHGRLDILVNNAAANPYFGHILDTDLAAYEKTVDVNIRGYFFMSV 128 Query: 514 EAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 EA + GGG+IV +S+ A QP + G Y ++K ++ +TKA A E IRVN + Sbjct: 129 EAGKLMKANGGGAIVNTASVNALQPGDRQGIYSITKAAVVNMTKAFAKECGPLGIRVNAL 188 >UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Chloroflexus|Rep: Short-chain dehydrogenase/reductase SDR - Chloroflexus aggregans DSM 9485 Length = 256 Score = 110 bits (264), Expect = 4e-23 Identities = 63/181 (34%), Positives = 96/181 (53%) Frame = +1 Query: 151 FSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCH 330 F GKVAIVT +GIG A A L EGA+VVI R + V+ + + G V+ Sbjct: 3 FQGKVAIVTGGAQGIGRATALALAREGAAVVIADRDAAATTALVEGINAWGGRALAVIAD 62 Query: 331 VANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLA 510 V++ R+ +FGG+D+L I T Q+W +I +VN+ +L++ Sbjct: 63 VSDESDAARIANDTVLEFGGIDLLVNNAGIQQPGT-IESTTLQLWQEIINVNLTGVFLVS 121 Query: 511 KEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNC 690 + PEL +RGGG+IV ++S+ + AY SK ++ LT+A+A + + IRVNC Sbjct: 122 RFVMPELRRRGGGAIVNVASVYGLRAEAGWAAYAASKGGVIALTRAMALDGAPDGIRVNC 181 Query: 691 V 693 V Sbjct: 182 V 182 >UniRef50_Q5NW77 Cluster: Short-chain alcohol dehydrogenase; n=2; Azoarcus sp. EbN1|Rep: Short-chain alcohol dehydrogenase - Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) Length = 247 Score = 109 bits (262), Expect = 6e-23 Identities = 66/185 (35%), Positives = 95/185 (51%), Gaps = 2/185 (1%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKE-SNVGKAVQSLRSEGITVEGVV 324 R K+AIVT + GIG A A RL EGA V K + KA+++ +G V Sbjct: 2 RLEKKIAIVTGAASGIGQATALRLAKEGAHVACFDFKSLDSTMKAIEAAGGNASAFQGDV 61 Query: 325 CHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXX-ILDTDEQVWDKIFDVNVKSSW 501 ++ + + +FG VD+L ILD E+ WD+I D+NVK +W Sbjct: 62 KRASDWAE---MVKQTVERFGRVDVLANIAGVVSIGSDNILDQTEEGWDRIMDINVKGTW 118 Query: 502 LLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIR 681 L KE P ++K GGG IV ++S+AA+ L AY SK ++ LT+ A E +NI+ Sbjct: 119 LGMKEVMPVMMKNGGGKIVNVASLAAHVGLTNLAAYSASKGAVVALTRYAAMEYAKDNIQ 178 Query: 682 VNCVA 696 VN V+ Sbjct: 179 VNAVS 183 >UniRef50_A3SFH7 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family protein; n=2; Sulfitobacter|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family protein - Sulfitobacter sp. EE-36 Length = 255 Score = 109 bits (262), Expect = 6e-23 Identities = 58/181 (32%), Positives = 100/181 (55%), Gaps = 1/181 (0%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGI-TVEGVVCH 330 +GKVA++T +++G+G A+AK L GA+VVI +RK+ + A + + G GV C+ Sbjct: 7 TGKVALLTGASKGMGLAMAKGLAEHGATVVISARKQDQLDAAAAEINALGKGKAFGVACN 66 Query: 331 VANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLA 510 V E + L + G +DI+ + + ++K + NV S+ LA Sbjct: 67 VGYKEQLQALVDETHKLAGKIDIVIGNAGVNPYYGPTSEIPDDAYEKTMNANVLSNLWLA 126 Query: 511 KEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNC 690 + P+++++G GS+ F SSI A++P+ LG YG+SK L+GL + +A E + +R N Sbjct: 127 QMVAPDMIEKGAGSMAFTSSIGAFKPSVMLGTYGMSKLALIGLVRNLAAEFGPKGLRFNA 186 Query: 691 V 693 + Sbjct: 187 I 187 >UniRef50_Q46UH8 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Ralstonia eutropha JMP134|Rep: Short-chain dehydrogenase/reductase SDR - Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) Length = 256 Score = 107 bits (258), Expect = 2e-22 Identities = 61/176 (34%), Positives = 89/176 (50%) Frame = +1 Query: 160 KVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVAN 339 KVA++T + GIG AIA S GA+VV R E+++ + +R G VA+ Sbjct: 26 KVAVITGAGRGIGRAIAMAYASAGAAVVCSGRGEADIAQTAAMIREAGGRAIAQTADVAD 85 Query: 340 HEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKEA 519 +E + LF+ A+ FGGVDI+ I D D +W K D+N+ ++ A A Sbjct: 86 YESVKTLFQRASDAFGGVDIVVANAGVALEQRRIADGDPALWRKTIDINLTGAYHTAHAA 145 Query: 520 YPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 L +RG G I+ I S +P AY SK+ L LT+++A E +NI VN Sbjct: 146 IAHLRRRGAGKIIMIGSGQRKRPAPGFSAYSCSKSGLWMLTQSLATELQEDNISVN 201 >UniRef50_A0NRY8 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Stappia aggregata IAM 12614|Rep: Short-chain dehydrogenase/reductase SDR - Stappia aggregata IAM 12614 Length = 270 Score = 107 bits (258), Expect = 2e-22 Identities = 60/189 (31%), Positives = 95/189 (50%) Frame = +1 Query: 118 ANPVRAIQSTRFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRS 297 A+P R +G+VA+VT ++ GIG A A+ L GA VV+ +R + ++ + +R+ Sbjct: 10 AHPERKRYMFDLTGQVALVTGASRGIGEAAARSLAKYGAKVVLAARSDKDIERIAGEIRA 69 Query: 298 EGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIF 477 EG VVC VA+++ + + A +GG+DIL I D+D W K+ Sbjct: 70 EGQDATAVVCDVADYDDVVKAVQTAVDTYGGLDILVNNAGVIEPIARIEDSDPAEWGKVI 129 Query: 478 DVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIAN 657 D+NVK + A ++ +G G++V ISS AA E Y SK L LT+ Sbjct: 130 DINVKGVYYGLHAAAKHMLAKGAGTVVNISSGAAVSALEGWSHYCASKAAALSLTRCADK 189 Query: 658 ETVHENIRV 684 E + +R+ Sbjct: 190 EFGDKGLRI 198 >UniRef50_Q5V0V4 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=4; Halobacteriaceae|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Haloarcula marismortui (Halobacterium marismortui) Length = 269 Score = 107 bits (257), Expect = 3e-22 Identities = 58/185 (31%), Positives = 91/185 (49%), Gaps = 2/185 (1%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVV- 324 R + AI+T ++ GIG AIA+ ++GA VV+CSR++ NVG + E V Sbjct: 17 RLENQRAIITGASSGIGRAIAEEFAADGADVVVCSREQDNVGPVADEINDSDRPGEAVAI 76 Query: 325 -CHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSW 501 C V + E L E +FGG+D+L D E W I D+N+ ++ Sbjct: 77 ECDVTDREAVEALVEATVDEFGGLDVLVNNAGASFMSGFD-DISENGWKTIVDINLHGTY 135 Query: 502 LLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIR 681 + A L GGG+++ +SS+A Q + YG +K + LT ++ E +IR Sbjct: 136 HCTQAAGDALAADGGGTVINLSSVAGEQGAPYMSHYGAAKAGVSNLTSTLSAEWADRDIR 195 Query: 682 VNCVA 696 +NC+A Sbjct: 196 INCIA 200 >UniRef50_Q8UDS8 Cluster: Short chain dehydrogenase; n=1; Agrobacterium tumefaciens str. C58|Rep: Short chain dehydrogenase - Agrobacterium tumefaciens (strain C58 / ATCC 33970) Length = 249 Score = 107 bits (256), Expect = 3e-22 Identities = 62/179 (34%), Positives = 90/179 (50%), Gaps = 1/179 (0%) Frame = +1 Query: 160 KVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVAN 339 KVAI+T ++ GIG A A ++GA+VVI +R E + + +R G V V Sbjct: 7 KVAIITGASSGIGRATAMLFVTQGAAVVINARGEKALQEVAADIRDAGGRVHAVAGDAGV 66 Query: 340 HEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKEA 519 E RL + A FGG+DI + + + WD + +VN+ S++L A+ Sbjct: 67 AETHSRLADAAVGVFGGLDIAINNAGAVGAMKPLAEISPEEWDHVLNVNLTSAFLGARYQ 126 Query: 520 YPELVKRGGGSIVFISSIAAYQPTEP-LGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 P ++KRGGGSIVF SS P + AYG +K L+GL K I + IR N + Sbjct: 127 IPPMLKRGGGSIVFTSSFVGTSAGIPGMSAYGTAKAALMGLVKGITADYAINGIRANAL 185 >UniRef50_Q1V2Q8 Cluster: Short chain dehydrogenase; n=2; Candidatus Pelagibacter ubique|Rep: Short chain dehydrogenase - Candidatus Pelagibacter ubique HTCC1002 Length = 258 Score = 107 bits (256), Expect = 3e-22 Identities = 64/185 (34%), Positives = 93/185 (50%), Gaps = 3/185 (1%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESN---VGKAVQSLRSEGITVEG 318 + ++AIVT +GIG I RL SEGA +VI N + K +Q E I VE Sbjct: 2 KLKDRIAIVTGGGKGIGAEICVRLASEGAKIVIAEMDIENGEKISKKIQGNNGEAIVVE- 60 Query: 319 VVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSS 498 +VA + + +VA KFG +DIL ILD +Q WD + VN+ Sbjct: 61 --TNVAEEDSANNMADVAIKKFGKIDILVNNAGIRHINN-ILDHTKQQWDDMISVNLTGP 117 Query: 499 WLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENI 678 +L K P ++K G G I+ SIA++ AY +K+ +LGLT+A+A + +NI Sbjct: 118 YLCCKSVIPHMIKNGKGKIINFGSIASFMGRPDRVAYVAAKSGILGLTRALAVDLTGKNI 177 Query: 679 RVNCV 693 VN + Sbjct: 178 NVNTI 182 >UniRef50_Q0K243 Cluster: Short chain dehydrogenase; n=3; Cupriavidus|Rep: Short chain dehydrogenase - Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)(Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier337)) Length = 255 Score = 107 bits (256), Expect = 3e-22 Identities = 58/179 (32%), Positives = 93/179 (51%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVA 336 G+VA++T ST G+G +A+ LG+ GA+VV+ R A L +EGI G+ C +A Sbjct: 9 GRVAVITGSTRGMGLEMARALGAAGAAVVVSGRDAGAARDAASQLEAEGIRATGIACDIA 68 Query: 337 NHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKE 516 + + R E A + +G VD L +L +V+D NV+ + +L Sbjct: 69 DVDSVRAFAEQALAAYGRVDALVLNAAASGQPGSMLSQGPEVFDAAMAGNVRGNLVLVNA 128 Query: 517 AYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 P+++ R GSI+F+SSIAA + + LG Y V+K + +++A E I VN + Sbjct: 129 LAPQMISRHDGSIIFMSSIAAKRGSAFLGMYSVTKAAIDQAVRSLALELGPSGINVNAI 187 >UniRef50_Q023X9 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Solibacter usitatus Ellin6076|Rep: Short-chain dehydrogenase/reductase SDR - Solibacter usitatus (strain Ellin6076) Length = 240 Score = 107 bits (256), Expect = 3e-22 Identities = 65/180 (36%), Positives = 93/180 (51%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 +GK AIVT T GIG A+A+RL EGA+V IC+R + V +AV ++ G V G V Sbjct: 5 NGKFAIVTGGTRGIGRAVAERLLREGAAVAICARDAAGVARAVDEMKQYG-KVFGAAADV 63 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 + E R F +FGG+DIL T E+ W + D+N+ ++ A Sbjct: 64 SQIESVRAFFHAVDREFGGLDILVNNAGQAAYRKVAEMTPEE-WHRNIDLNLSGAFYCAH 122 Query: 514 EAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 EA + RGGG IV ISS+A Y SK L G T+A+ + ++N+RV+ + Sbjct: 123 EALARFLPRGGGFIVNISSLAGRNAFTGGAGYNASKFGLNGFTEALMLDHRNDNVRVSSI 182 >UniRef50_P50162 Cluster: Tropinone reductase 1; n=77; Viridiplantae|Rep: Tropinone reductase 1 - Datura stramonium (Jimsonweed) (Common thornapple) Length = 273 Score = 107 bits (256), Expect = 3e-22 Identities = 58/180 (32%), Positives = 93/180 (51%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVA 336 G A+VT ++GIGYAI + L GA V CSR E + + ++ R +G+ VEG VC + Sbjct: 21 GTTALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDECLEIWREKGLNVEGSVCDLL 80 Query: 337 NHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKE 516 + R +L + F G + D E+ ++ I N ++++ L++ Sbjct: 81 SRTERDKLMQTVAHVFDGKLNILVNNAGVVIHKEAKDFTEKDYNIIMGTNFEAAYHLSQI 140 Query: 517 AYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVA 696 AYP L G+++F+SSIA + + Y SK + +TK++A E +NIRVN VA Sbjct: 141 AYPLLKASQNGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKSLACEWAKDNIRVNSVA 200 >UniRef50_Q8LFZ4 Cluster: Short chain alcohol dehydrogenase-like; n=5; Magnoliophyta|Rep: Short chain alcohol dehydrogenase-like - Arabidopsis thaliana (Mouse-ear cress) Length = 264 Score = 106 bits (255), Expect = 5e-22 Identities = 60/181 (33%), Positives = 92/181 (50%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 +GK A+VT T GIG A+ + L A V CSR + + + ++ G+ V G VC Sbjct: 10 AGKTALVTGGTRGIGRAVVEELAKFCAKVHTCSRNQEELNACLNDWKANGLVVSGSVCDA 69 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 + + R +L + A+S F G + ++ + + KI N++S++ L++ Sbjct: 70 SVRDQREKLIQEASSAFSGKLNILINNVGTNVRKPTVEYSSEEYAKIMSTNLESAFHLSQ 129 Query: 514 EAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 A+P L G GSIVFISS+A YG +K L LT+ +A E +NIR NCV Sbjct: 130 IAHPLLKASGVGSIVFISSVAGLVHLSSGSIYGATKGALNQLTRNLACEWASDNIRTNCV 189 Query: 694 A 696 A Sbjct: 190 A 190 >UniRef50_Q0FK50 Cluster: Putative uncharacterized protein; n=1; Roseovarius sp. HTCC2601|Rep: Putative uncharacterized protein - Roseovarius sp. HTCC2601 Length = 258 Score = 106 bits (254), Expect = 6e-22 Identities = 58/183 (31%), Positives = 93/183 (50%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 R +GK A++T + GIG A A EGA+V + + + V+++R+ G T EG Sbjct: 9 RLAGKTAVITGAGSGIGRAAASIFAREGAAVAVWDIVPERIAETVEAVRAAGGTAEGFTV 68 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 +++ + G V +L L TDE +WD+I V++K WL+ Sbjct: 69 DISDSASIAEAARATENSLGPVRVLFNNAGILDDYADALTTDEALWDRIMGVDLKGMWLV 128 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 +K P ++ GGG+IV ++SIAA+ AY +K ++G T+ +A E + IRVN Sbjct: 129 SKALLPGMIDAGGGAIVNVASIAAFIAGGGGIAYTTAKHGVVGFTRQLALEYAPKGIRVN 188 Query: 688 CVA 696 VA Sbjct: 189 AVA 191 >UniRef50_Q3ACJ4 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=1; Carboxydothermus hydrogenoformans Z-2901|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Carboxydothermus hydrogenoformans (strain Z-2901 / DSM 6008) Length = 249 Score = 105 bits (253), Expect = 8e-22 Identities = 62/181 (34%), Positives = 95/181 (52%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 +GKV IVT ++GIG+A AKR+ EGA VVI +R + KA LR +G+ V + C V Sbjct: 5 TGKVGIVTGGSKGIGFATAKRIAEEGAKVVIANRNKEEGEKAALQLREKGLEVYSIPCDV 64 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 ++L ++G +DIL I + E+ W+ + D+N+K ++ Sbjct: 65 GKVADIKKLVSEVYGRYGRIDIL-VNCAGVNVRKPIEEYTEEDWNYMVDINLKGTFFACI 123 Query: 514 EAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 EA ++ + G IV ++SI A + G Y +K + LTKA+A E NIRVN V Sbjct: 124 EAGKHMIAQKEGVIVNLASIQAEEVLPERGIYATTKGGVKQLTKALAVEWAKYNIRVNAV 183 Query: 694 A 696 + Sbjct: 184 S 184 >UniRef50_A6F000 Cluster: Putative short-chain dehydrogenase/reductase; n=1; Marinobacter algicola DG893|Rep: Putative short-chain dehydrogenase/reductase - Marinobacter algicola DG893 Length = 255 Score = 105 bits (253), Expect = 8e-22 Identities = 66/189 (34%), Positives = 90/189 (47%), Gaps = 4/189 (2%) Frame = +1 Query: 142 STRFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGV 321 S+R G+VAIVT GIG A A+RL EGASVVI A + L EG V Sbjct: 2 SSRLKGRVAIVTGGGHGIGRAYARRLAEEGASVVIAEIDVKAATSAAEELEKEGFEALAV 61 Query: 322 VCHVANHEHRRRLFEVATSKFGGVDIL----XXXXXXXXXXXXILDTDEQVWDKIFDVNV 489 V + + + +A KFG +DIL + D + WD++ VNV Sbjct: 62 HTDVTKPDSVKEMARLAAEKFGRIDILVNNAAIFISVPMSRAPFDEIDPEEWDRMMAVNV 121 Query: 490 KSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVH 669 K +WL + P + + G I+ ISS A + + Y SK +LG TK +ANE Sbjct: 122 KGAWLSSCAVAPYMRDQQYGKIINISSGTALKGADNRIHYVASKAAILGFTKTLANELGK 181 Query: 670 ENIRVNCVA 696 E + VNC+A Sbjct: 182 EGVCVNCIA 190 >UniRef50_A5V310 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Sphingomonas wittichii RW1|Rep: Short-chain dehydrogenase/reductase SDR precursor - Sphingomonas wittichii RW1 Length = 248 Score = 105 bits (253), Expect = 8e-22 Identities = 62/183 (33%), Positives = 96/183 (52%), Gaps = 1/183 (0%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 RF GKVAIVT + GIG A RL SEGA VV + N K ++ + G G++C Sbjct: 4 RFEGKVAIVTGAGAGIGRACMARLASEGAIVV---GTDVNQAKLDDAVAAAGANAHGMIC 60 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXIL-DTDEQVWDKIFDVNVKSSWL 504 VA+ + ++FGGV +L L + + WDK+ VNV+ +L Sbjct: 61 DVADQAAIDAMVADVVARFGGVHVLINNAGIGNPRRLRLHEQPPEDWDKVMGVNVRGVYL 120 Query: 505 LAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRV 684 + + P ++++GGGSIV ++S +++ T Y SK +L +T+A A + +NIR+ Sbjct: 121 MQRAVIPHMLRQGGGSIVNMASTGSFRATALSSPYITSKGAVLMMTRAAAADYARDNIRI 180 Query: 685 NCV 693 N V Sbjct: 181 NAV 183 >UniRef50_Q0IBU9 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase BH0932; n=3; Bacteria|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase BH0932 - Synechococcus sp. (strain CC9311) Length = 258 Score = 105 bits (252), Expect = 1e-21 Identities = 62/183 (33%), Positives = 93/183 (50%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 + GKVA+VT + GIG A A R GSEG +V IC+R E + K + L+ G+ GVV Sbjct: 4 QLKGKVALVTGGSRGIGRATALRFGSEGCNVAICARGEEGLNKTLGELKDLGVMTFGVVA 63 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 ++ R + A GGVD+L DE W K F++N+ + Sbjct: 64 DMSIAGEAARFVDEAADALGGVDMLVNNVGGSSNSTFSEACDED-WLKAFNLNLFHAVRA 122 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 + + P KR GGS+V I+SI+ ++P YG +K + L+ ++A E +N RVN Sbjct: 123 TRASLPYFRKRRGGSVVTIASISGWRPAPDKAIYGATKAAEIFLSSSLAWELSPQNERVN 182 Query: 688 CVA 696 V+ Sbjct: 183 TVS 185 >UniRef50_Q6N3Z1 Cluster: Putative oxidoreductase, short-chain dehydrogenase/reductase family precursor; n=1; Rhodopseudomonas palustris|Rep: Putative oxidoreductase, short-chain dehydrogenase/reductase family precursor - Rhodopseudomonas palustris Length = 239 Score = 105 bits (251), Expect = 1e-21 Identities = 66/183 (36%), Positives = 97/183 (53%), Gaps = 2/183 (1%) Frame = +1 Query: 151 FSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGI--TVEGVV 324 F+GK A+VT ++GIG+AIA+ L GASV+IC+R ES + +A+ +LR+ G+ V G+ Sbjct: 3 FAGKAALVTGGSKGIGFAIAQALAQAGASVMICARDESEIAQALPALRN-GVRGRVHGLA 61 Query: 325 CHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWL 504 C V + R+L + + F G+DIL E W D N+ ++ Sbjct: 62 CDVRDEAEVRQLVDHTVTAFDGLDILVNNAGVGLLGPVETFPPEH-WRLTLDTNLTGAFY 120 Query: 505 LAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRV 684 A P L RGGG+IV I S ++ AY SK LLGL++++ E IRV Sbjct: 121 CCHYAIPALKARGGGAIVNIGSRSSVNAYGGGAAYCASKFGLLGLSESLLQELHPFGIRV 180 Query: 685 NCV 693 +CV Sbjct: 181 SCV 183 >UniRef50_Q39TG1 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Geobacter metallireducens GS-15|Rep: Short-chain dehydrogenase/reductase SDR - Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210) Length = 266 Score = 104 bits (250), Expect = 2e-21 Identities = 68/182 (37%), Positives = 96/182 (52%), Gaps = 2/182 (1%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 SGK A+VT + GIGYAIAKRL GA+V+I + +A L S V+ +V Sbjct: 16 SGKRAVVTGAAAGIGYAIAKRLAEAGATVLITDINREAIEEAEHRLSSMKCKVKSLVSDA 75 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 + LF FGGVDIL ILD + W ++ +N++S++L ++ Sbjct: 76 GREADIKSLFSYVADSFGGVDIL-VNNAGIYPATKILDMSLEQWREVIRINLESAFLCSQ 134 Query: 514 EAYPELVKRG-GGSIVFISSIAAYQPTEP-LGAYGVSKTTLLGLTKAIANETVHENIRVN 687 EA +V++G GG IV ISS+AA +P P L YG SK ++ LT++ A E IR Sbjct: 135 EAGRIMVRQGTGGVIVNISSMAALKPCFPGLAHYGASKGGVVNLTRSTALELAPHKIRAV 194 Query: 688 CV 693 V Sbjct: 195 AV 196 >UniRef50_Q62E13 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n=23; Proteobacteria|Rep: 7-alpha-hydroxysteroid dehydrogenase - Burkholderia mallei (Pseudomonas mallei) Length = 256 Score = 104 bits (249), Expect = 2e-21 Identities = 55/180 (30%), Positives = 89/180 (49%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 SGK+A+VT + GIG +AK LG+ GA VV+ SR+ + + + G + E CH+ Sbjct: 10 SGKIAVVTGGSRGIGAEVAKLLGAFGAHVVVTSRRLDDCRAIADEIVAAGGSAEAAACHI 69 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 E L+ + G +D+L I+DTD + K DVN++ + ++ Sbjct: 70 GELEQIDALYASLEGRHGRLDVLVNNAATNPYYGPIVDTDLGAFQKTVDVNIRGYFFMSS 129 Query: 514 EAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 + K GGGSIV ++S+ P G Y ++K ++ +TKA A E +R N + Sbjct: 130 RGAKLMGKNGGGSIVNVASVNGVIPGYWQGIYSITKAAVISMTKAFAIECAASGVRCNAL 189 >UniRef50_Q7W2M6 Cluster: Alcohol dehydrogenase; n=15; cellular organisms|Rep: Alcohol dehydrogenase - Bordetella parapertussis Length = 252 Score = 103 bits (248), Expect = 3e-21 Identities = 60/182 (32%), Positives = 91/182 (50%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 R +GK AIVT + G G IA EGA VV+ E+ + ++ + G V Sbjct: 2 RLNGKTAIVTGAGSGFGEGIAATFAREGAKVVVADINEAGGQRVAAAINAAGGQAVFVRA 61 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 V+++ L FGG+DI+ +L+ +E +D+I+ +NVKS +L Sbjct: 62 DVSDNAAVANLLAATLKAFGGLDIVVNNAGTTHRNRPMLEVEEDEFDRIYAINVKSIYLT 121 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 A+ P GGGS + I+S AA +P L Y SK ++ +K++A E +NIRVN Sbjct: 122 ARHMVPHFRAHGGGSFINIASTAAIRPRPGLTWYNGSKGAVVTTSKSMAAELGPDNIRVN 181 Query: 688 CV 693 CV Sbjct: 182 CV 183 >UniRef50_Q1IPD7 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Acidobacteria bacterium Ellin345|Rep: Short-chain dehydrogenase/reductase SDR - Acidobacteria bacterium (strain Ellin345) Length = 244 Score = 103 bits (248), Expect = 3e-21 Identities = 57/179 (31%), Positives = 88/179 (49%) Frame = +1 Query: 160 KVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVAN 339 +V++VT S+ G+G AIA+RL GA+VVI +R + QS+R G E V C V N Sbjct: 14 QVSVVTGSSRGMGAAIARRLAIMGAAVVITARHAEGLSATAQSIRENGGQCEAVPCDVTN 73 Query: 340 HEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKEA 519 + KFG +DIL + + W+++ N++ + L + Sbjct: 74 LAQVEAVGRAVEKKFGRIDILVNNAGIGSMGRKLWEFPPDEWERVMSTNLRGPYYLIRTF 133 Query: 520 YPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVA 696 P +++ G I+ ISS+A P AY SK L GLT ++A E N+RV+ V+ Sbjct: 134 APMMIRANSGHIINISSLAGKNPLPNGAAYSASKWGLNGLTLSVAEELRSHNVRVSLVS 192 >UniRef50_Q4IUB1 Cluster: Short-chain dehydrogenase/reductase SDR; n=5; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Azotobacter vinelandii AvOP Length = 263 Score = 103 bits (247), Expect = 4e-21 Identities = 62/179 (34%), Positives = 94/179 (52%), Gaps = 1/179 (0%) Frame = +1 Query: 160 KVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNV-GKAVQSLRSEGITVEGVVCHVA 336 KVA++T S+ GIG +A+ L +EG VV+ +R V +A + + G+ GV C V+ Sbjct: 8 KVAVITGSSTGIGLTVAEGLATEGVRVVLSARGADRVIVEAARIADTYGVETLGVACDVS 67 Query: 337 NHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKE 516 + E L T +FGG DIL + DE+ W +D++V ++ LA+ Sbjct: 68 SKEGVETLIAAVTDRFGGADILINNAGTGSNETVMQAPDEK-WQHYWDLHVMAAVRLARG 126 Query: 517 AYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 P + RGGG I+ +SI A QP Y V+K L+ +K +A E + +NIRVN V Sbjct: 127 LAPGMKMRGGGVILHNASICAVQPLGYEPIYNVTKAALMMFSKNLATELIKDNIRVNTV 185 >UniRef50_Q1AYL3 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain dehydrogenase/reductase SDR - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 251 Score = 103 bits (246), Expect = 6e-21 Identities = 61/182 (33%), Positives = 88/182 (48%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 R GKV +VT GIG A A L EGA VV+ K V+ ++ EG V C Sbjct: 2 RLEGKVCVVTGGATGIGEASALALAREGARVVVGDVNVEEGRKTVEDIKKEGGEALFVEC 61 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 V+ E RRL E FG +D+L + + + W + F VNV + Sbjct: 62 DVSREEGARRLVEETVGAFGRIDVLFNNAGINITEGSVPEMKVEDWRRTFAVNVDGIFWC 121 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 ++ A PE+ K GGG I+ +S +++ AY SK ++ LT+A+A + ENIRVN Sbjct: 122 SRYAIPEMRKNGGGRIINTASPSSFVGWAGNAAYIASKGAVMSLTRAMAMDHAKENIRVN 181 Query: 688 CV 693 + Sbjct: 182 AI 183 >UniRef50_Q0TU60 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family; n=3; Clostridium perfringens|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family - Clostridium perfringens (strain ATCC 13124 / NCTC 8237 / Type A) Length = 272 Score = 103 bits (246), Expect = 6e-21 Identities = 59/183 (32%), Positives = 96/183 (52%), Gaps = 1/183 (0%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 RFS KV I+T + GIG A+A R EGA +V+ RKE + ++ +R VE ++C Sbjct: 8 RFSDKVMIITGAAGGIGKAVALRAAKEGAKLVLADRKEEMSKETLKEIREITSNVEFLIC 67 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 + E+ +++ + A KFGG+DIL + + E+++ + D N+ ++ Sbjct: 68 DLREGENCKKVIDTAIKKFGGLDILINNAGITGTPAPVHEMSEEMFRNVLDCNIMIAFHC 127 Query: 508 AKEAYPELVKRG-GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRV 684 + E++K+ GG+IV +SS+A AY SK L GLT+ +A + IRV Sbjct: 128 SHYGIQEMIKQNKGGAIVNVSSVAGLTGFPGHSAYVTSKHGLNGLTRNMALDYARYGIRV 187 Query: 685 NCV 693 N V Sbjct: 188 NAV 190 >UniRef50_Q2NIC9 Cluster: Predicted short chain dehydrogenase; n=2; Euryarchaeota|Rep: Predicted short chain dehydrogenase - Methanosphaera stadtmanae (strain DSM 3091) Length = 253 Score = 103 bits (246), Expect = 6e-21 Identities = 56/183 (30%), Positives = 88/183 (48%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 + GKVAI+T +T GIG +IA EGAS ++ +R++ + + + S G + Sbjct: 2 KLKGKVAIITGATAGIGKSIAYLFAEEGASTILIARRKERLEQITNEINSNGGDASACIG 61 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 V E + ++A K+G +DI+ + D+ +WDK DVN+ L Sbjct: 62 DVTKQEDIDNVVKLALDKYGKIDIIVNNAGIMDDFVSVKHIDDDLWDKTIDVNLTGPMRL 121 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 + PE++K GG+I+ ISS+ AY SK ++GL K A NIR N Sbjct: 122 IRAVIPEMIKNNGGNIITISSVGGLIGKISGAAYTASKHGVIGLAKHTAWVYGKHNIRSN 181 Query: 688 CVA 696 +A Sbjct: 182 VIA 184 >UniRef50_Q0B254 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Burkholderia ambifaria AMMD|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia cepacia (strain ATCC 53795 / AMMD) Length = 252 Score = 102 bits (244), Expect = 1e-20 Identities = 66/184 (35%), Positives = 89/184 (48%), Gaps = 2/184 (1%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 R KVA+VT +T GIG A A EGA V I +R+E + V+ + G V Sbjct: 3 RLFDKVALVTGATSGIGKATAMLFAREGAKVAIAARREEEGRQVVREILDHGGEAIFVRT 62 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 VA E + FG +DI + DTDEQ W + DVN+ ++L Sbjct: 63 DVAQAEDCAAAVARTVASFGKLDIAFNNAGITSFGRPVADTDEQAWSTVIDVNLTGTFLS 122 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGA--YGVSKTTLLGLTKAIANETVHENIR 681 K PE++K GGGSI+ +SS A GA Y SK ++GLT+A A E E +R Sbjct: 123 MKYEIPEILKAGGGSIINMSS-AYGLAGSAFGACSYHASKHGVIGLTRAAALEYAKEKLR 181 Query: 682 VNCV 693 VN + Sbjct: 182 VNAI 185 >UniRef50_A3YE37 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Marinomonas sp. MED121|Rep: Short-chain dehydrogenase/reductase SDR - Marinomonas sp. MED121 Length = 255 Score = 102 bits (244), Expect = 1e-20 Identities = 51/181 (28%), Positives = 91/181 (50%) Frame = +1 Query: 151 FSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCH 330 F +V ++T ++ G+G AK+ +GA + +C + + L +G V C Sbjct: 4 FKDQVVLITGASGGLGKEAAKQFAQQGAKLALCDLNVAALNDLGTELIEQGYEVFSQPCD 63 Query: 331 VANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLA 510 V+N + + + + FG +D+ + D D + ++++ D+NVK +L Sbjct: 64 VSNEQEVQSFIDNTAAHFGRLDVAINNAGIDPKHSTLADMDTRDFERVMDINVKGVYLCM 123 Query: 511 KEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNC 690 K P ++K+GGG+I +SS+A + AY SK ++GLTK++A+E IRVN Sbjct: 124 KYQIPHMIKQGGGAICNMSSVAGISGAPFMSAYAASKHAVIGLTKSVAHEYGRAGIRVNS 183 Query: 691 V 693 V Sbjct: 184 V 184 >UniRef50_A1IED1 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep: Short-chain dehydrogenase/reductase SDR precursor - Candidatus Desulfococcus oleovorans Hxd3 Length = 266 Score = 102 bits (244), Expect = 1e-20 Identities = 56/180 (31%), Positives = 90/180 (50%), Gaps = 1/180 (0%) Frame = +1 Query: 160 KVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVAN 339 K A+VT + GIG A A GA V I SRK N+ + ++++G V HV Sbjct: 12 KTALVTGGSMGIGRATALAFADAGADVAIVSRKMENLAPVAEEIKAKGKRCLPVAAHVGR 71 Query: 340 HEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKEA 519 + + E ++FG +DIL I + E++WD I +N+K + L++ Sbjct: 72 MDQLPAIVEQVVAEFGQIDILVNNAATSPAYATIFEAQEKLWDSIIGLNLKGLYFLSQAV 131 Query: 520 YPELVKRG-GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVA 696 + ++G GGSI+ +SSI + P +G Y +SK + T+++A E IRVN +A Sbjct: 132 ARVMEEKGAGGSIINVSSIDGFAPQAQVGIYSISKAGVNMATRSMALELAPHKIRVNAIA 191 >UniRef50_UPI000051AB3C Cluster: PREDICTED: similar to CG10672-PA, partial; n=1; Apis mellifera|Rep: PREDICTED: similar to CG10672-PA, partial - Apis mellifera Length = 121 Score = 101 bits (243), Expect = 1e-20 Identities = 50/89 (56%), Positives = 63/89 (70%) Frame = +1 Query: 136 IQSTRFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVE 315 I+ R KVAIVTAST GIG+AIAKRL EGA VVI SRKESNV +A++ L+S+ + V Sbjct: 23 IKCKRLEEKVAIVTASTSGIGFAIAKRLAEEGAKVVISSRKESNVQQALKQLKSKDLNVY 82 Query: 316 GVVCHVANHEHRRRLFEVATSKFGGVDIL 402 G +CHV +E R+ L E +FG +DIL Sbjct: 83 GTICHVGKNEDRKSLLEKTIQEFGSLDIL 111 >UniRef50_Q1IU02 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Acidobacteria bacterium Ellin345|Rep: Short-chain dehydrogenase/reductase SDR precursor - Acidobacteria bacterium (strain Ellin345) Length = 271 Score = 101 bits (243), Expect = 1e-20 Identities = 58/180 (32%), Positives = 92/180 (51%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 SGKVA+VT GIG A A+++ GASV I E K ++R+ G + C V Sbjct: 6 SGKVAVVTGGAMGIGEACARKIALAGASVAILDPNEDAGTKTAAAIRAHGGECKFFRCDV 65 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 + + + +K +DIL ++ T E WD++ VN+K +L++K Sbjct: 66 SKSKDVEQAVGDVITKHSQIDILVSNAGIQYYGD-VITTPEDDWDRVIGVNLKGCFLISK 124 Query: 514 EAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 P ++ GG +IV + S+ ++ + AY SK +LGL +A+A + H+ IRVNCV Sbjct: 125 FCVPHMISNGG-AIVVLGSVQSFTAIQNSAAYVTSKHAVLGLARAMALDYAHKGIRVNCV 183 >UniRef50_Q0LSE4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Caulobacter sp. K31|Rep: Short-chain dehydrogenase/reductase SDR - Caulobacter sp. K31 Length = 277 Score = 101 bits (243), Expect = 1e-20 Identities = 61/186 (32%), Positives = 93/186 (50%) Frame = +1 Query: 136 IQSTRFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVE 315 +Q+ R GK+AIVT + G+G AIAKR EGA+VV+ E + L G Sbjct: 1 MQAQRLQGKIAIVTGAARGLGAAIAKRYLEEGATVVLADLSEEKTTERAAEL---GAGAH 57 Query: 316 GVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKS 495 G C V + E L + ++FG +DIL + Q WD + VNV S Sbjct: 58 GRRCDVGDWEAFSTLIDATVAEFGRLDILVNNAGINRAGL-VPGFSLQHWDDLLRVNVSS 116 Query: 496 SWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHEN 675 + + A P + ++GGG+I+ ++SIA + AY SK ++ T+++A + EN Sbjct: 117 VFYGCRAAIPHMRRQGGGAIINVASIAGLRGETLAAAYSASKAAVVNFTRSLALDHADEN 176 Query: 676 IRVNCV 693 IRVN + Sbjct: 177 IRVNAI 182 >UniRef50_UPI00015BAF2E Cluster: short-chain dehydrogenase/reductase SDR; n=1; Ignicoccus hospitalis KIN4/I|Rep: short-chain dehydrogenase/reductase SDR - Ignicoccus hospitalis KIN4/I Length = 261 Score = 101 bits (241), Expect = 2e-20 Identities = 61/180 (33%), Positives = 92/180 (51%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 +GK +VTAST+GIG A+A+ EGA V I SR+E NV +A++ L G V G + Sbjct: 6 AGKRVLVTASTKGIGLAVAREFLKEGAKVFISSRREENVKRALEELSPLG-EVRGTTADL 64 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 + E R RL A GGVD+ +T + W++ + + ++S+ L K Sbjct: 65 RSKEDRERLVGEARKALGGVDVF-VFNSGGPPAKAFEETTLEDWEEAYKLLLESAAHLTK 123 Query: 514 EAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 PE+V+RG G +V+I+S+A P E L + + GL K + E + I N V Sbjct: 124 LVLPEMVERGWGRVVYITSVAIKMPLEGLVLSNAVRVGIAGLMKTLVKEYAGKGITFNSV 183 >UniRef50_A0YD08 Cluster: Short chain dehydrogenase; n=2; Gammaproteobacteria|Rep: Short chain dehydrogenase - marine gamma proteobacterium HTCC2143 Length = 259 Score = 100 bits (240), Expect = 3e-20 Identities = 59/184 (32%), Positives = 83/184 (45%) Frame = +1 Query: 142 STRFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGV 321 ST FSG+VA+VT GIG A EG +VV+ + + V ++++ G V Sbjct: 2 STTFSGQVALVTGGAAGIGRTTAAAFAREGLNVVVADMDKDGGEETVAAIKAAGGNAIFV 61 Query: 322 VCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSW 501 C V + L E S +G VD + E +D I VNVK W Sbjct: 62 PCDVTKESDVQWLIETTCSTYGSVDYAFNNAGIDIEKGELSKGTEDEFDSIMAVNVKGVW 121 Query: 502 LLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIR 681 L K +++ +GGG+IV SSI + Y SK ++GLTK+ A E IR Sbjct: 122 LCMKHQITQMITQGGGTIVNTSSIGGLGAAPNMSIYCASKHAVIGLTKSAAVENARNGIR 181 Query: 682 VNCV 693 +N V Sbjct: 182 INAV 185 >UniRef50_Q39TG6 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Geobacter metallireducens GS-15|Rep: Short-chain dehydrogenase/reductase SDR - Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210) Length = 257 Score = 100 bits (239), Expect = 4e-20 Identities = 52/184 (28%), Positives = 91/184 (49%), Gaps = 4/184 (2%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVA 336 GK AI+T + G+G +A+ GAS+V+CSR A ++R G+ + + C + Sbjct: 11 GKTAIITGGSRGLGLMMAEGFAEAGASLVLCSRNLEQCEDAAANIRKLGVECDALRCDIG 70 Query: 337 NHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKE 516 + + + ++FG +DIL + DT + WD+++ NV+ ++ E Sbjct: 71 EQDEVKAVVAHTMNRFGKIDIL-VNNAGISWGGELQDTPLKKWDQLYSTNVRGNYFFTTE 129 Query: 517 AYPELVKRGGGSIVFISSIAAYQPTEP----LGAYGVSKTTLLGLTKAIANETVHENIRV 684 ++ GGG+I+ I SI + T+P AY +K ++ LTK ++ NIRV Sbjct: 130 VVSPMIAGGGGNIINIVSIGGVRSTDPKVVTFPAYASTKGAIIALTKHLSRNWAKHNIRV 189 Query: 685 NCVA 696 N +A Sbjct: 190 NAIA 193 >UniRef50_Q1D6R5 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=1; Myxococcus xanthus DK 1622|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Myxococcus xanthus (strain DK 1622) Length = 501 Score = 100 bits (239), Expect = 4e-20 Identities = 65/183 (35%), Positives = 90/183 (49%), Gaps = 1/183 (0%) Frame = +1 Query: 151 FSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVG-KAVQSLRSEGITVEGVVC 327 F+GKVA VT S +GIG IA RL GA+VV+ S + G + VQ + G Sbjct: 219 FAGKVAFVTGSGKGIGKVIAARLAGSGATVVVNSFHSRDEGERTVQEIVDAGGKAFHAWG 278 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 VA EH R+F ++FGG+D L T WDK F + ++ Sbjct: 279 SVAQEEHLDRMFASIEAQFGGLDFLVCNASNGLIGPFDRITPRD-WDKAFRTCITGTYEC 337 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 A A P + +RGGGSIV +S+ + + LG GV K + LT+ +A E + IR N Sbjct: 338 AMRARPLMARRGGGSIVTMSTSMSQRYMHDLGCQGVVKAGVESLTRYLAAELAPDGIRTN 397 Query: 688 CVA 696 CV+ Sbjct: 398 CVS 400 >UniRef50_Q8R9W0 Cluster: Dehydrogenases with different specificities; n=4; Bacteria|Rep: Dehydrogenases with different specificities - Thermoanaerobacter tengcongensis Length = 247 Score = 99 bits (238), Expect = 5e-20 Identities = 54/180 (30%), Positives = 91/180 (50%), Gaps = 1/180 (0%) Frame = +1 Query: 160 KVAIVTASTEGIGYAIAKRLGSEGASVVICSRKES-NVGKAVQSLRSEGITVEGVVCHVA 336 +VA VT + GIG AIA RL +G ++ I K+ + + V+ ++ G+ + C V+ Sbjct: 6 RVAFVTGGSRGIGRAIAVRLAKDGFNIAITYVKDDKSAEEVVEEVKKHGVDALAIKCDVS 65 Query: 337 NHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKE 516 + + E +FG +D++ IL +E+ WD++ DVN+K ++ + K Sbjct: 66 KYHEVEKAVEKVIEEFGSIDVVVNNAGITKDNL-ILKMEEEEWDQVIDVNLKGAFNVIKF 124 Query: 517 AYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVA 696 A ++K+ G I+ ISS+ Y SK ++GLTK++A E I VN VA Sbjct: 125 ASKYMIKKRKGKIINISSVVGLMGNVGQANYAASKAGIIGLTKSVAKELASRGITVNAVA 184 >UniRef50_A6WB74 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Kineococcus radiotolerans SRS30216|Rep: Short-chain dehydrogenase/reductase SDR precursor - Kineococcus radiotolerans SRS30216 Length = 247 Score = 99 bits (238), Expect = 5e-20 Identities = 63/183 (34%), Positives = 99/183 (54%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 R G+ A+VT ST GIG A+A L + GA V++ R ++ AVQSL + G T E + Sbjct: 4 RLEGRTALVTGSTSGIGRAVAAVLAARGAHVLVSGRDDTRGRDAVQSLVNAGGTAEYLPA 63 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 ++ R L + A G VDIL +++ + D+++ +NVK+ +LL Sbjct: 64 DLSAASGVRELADAALDLAGTVDILVNNAGVFSFGSTAGNSEIDI-DRMYAINVKAPYLL 122 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 + P++V++G G+IV + + AA++ + G YG SK LL LT A A E +RVN Sbjct: 123 VQALAPKMVEQGSGTIVNVLTGAAHRGSVTAGLYGSSKAALLLLTTAWAAEFGPSGVRVN 182 Query: 688 CVA 696 V+ Sbjct: 183 AVS 185 >UniRef50_A7EQI6 Cluster: Putative uncharacterized protein; n=1; Sclerotinia sclerotiorum 1980|Rep: Putative uncharacterized protein - Sclerotinia sclerotiorum 1980 Length = 249 Score = 99.5 bits (237), Expect = 7e-20 Identities = 62/187 (33%), Positives = 93/187 (49%), Gaps = 1/187 (0%) Frame = +1 Query: 136 IQSTRFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVE 315 + +R KVAIVT G G AIA+R EG V I ++ G+ V ++ + Sbjct: 9 VLGSRLKNKVAIVTGGGSGFGEAIARRFAGEGCKVTIADI-DAVGGERVANVHPHSMLF- 66 Query: 316 GVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKS 495 V V N E R+ E +K+G VD+ LD E +DK+F+VNVKS Sbjct: 67 -VKMDVTNEEDWERVLETTLAKWGRVDVCVNNAGTSYRNKPTLDVIEDEFDKVFNVNVKS 125 Query: 496 SWLLAKEAYPELVKRG-GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHE 672 + + P ++ +G GGS++ I+SI A +P L Y SK ++ TK +A E + Sbjct: 126 IFYATRHFIPNVINQGEGGSMINIASIGASRPRAGLVWYNASKAAVVNATKGLAAEYGPK 185 Query: 673 NIRVNCV 693 NIR+N + Sbjct: 186 NIRINSI 192 >UniRef50_P55541 Cluster: Uncharacterized short-chain type dehydrogenase/reductase y4lA; n=5; Rhizobiales|Rep: Uncharacterized short-chain type dehydrogenase/reductase y4lA - Rhizobium sp. (strain NGR234) Length = 278 Score = 99.5 bits (237), Expect = 7e-20 Identities = 61/186 (32%), Positives = 88/186 (47%), Gaps = 3/186 (1%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 RF GKVA+VT + GIG A A + EG VV+ S + +E + Sbjct: 3 RFEGKVAVVTGAGAGIGKACALAIAREGGRVVVADLDGSAAIACTAQIAAEAGNALAMAM 62 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXX---ILDTDEQVWDKIFDVNVKSS 498 +A+ + LFE A FGGVD+L ILD D VWD+ N++ + Sbjct: 63 DIADAQAVAALFETAERHFGGVDLLVNNASAMHLTPRDRAILDLDLAVWDQTMATNLRGT 122 Query: 499 WLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENI 678 L ++A P ++ RGGG+IV +SS +Y VSK + L+ ++A + H I Sbjct: 123 LLCCRQAIPRMIARGGGAIVNMSSCQGLSGDTAQTSYAVSKAAMNMLSASLATQYGHAQI 182 Query: 679 RVNCVA 696 R N VA Sbjct: 183 RCNAVA 188 >UniRef50_Q39ME1 Cluster: Short-chain dehydrogenase/reductase SDR; n=6; Burkholderiales|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 249 Score = 99.1 bits (236), Expect = 9e-20 Identities = 61/183 (33%), Positives = 93/183 (50%), Gaps = 2/183 (1%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 +GKVAIVT S G+G A A+RL EGASVVI ++L+ EG+ +V + Sbjct: 6 TGKVAIVTGSARGLGAATARRLAQEGASVVITDINAELAQATAKALQDEGLAAHCIVGDI 65 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXI-LDTDEQVWDKIFDVNVKSSWLLA 510 +RL + + FGGV IL + + D+ WD + +V +K ++L A Sbjct: 66 TQEADVQRLVDETVAHFGGVHILVNNAGAPRDKYLVKMSADD--WDFVMNVMLKGAFLAA 123 Query: 511 KEAYPELVKRGGGSIVFISSIAAY-QPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 + P +++G G ++ ISS A PT+ Y +K L+G+ KA++ E I N Sbjct: 124 RAVMPHFIEQGWGRLINISSRAHLGNPTQ--ANYSAAKAGLIGMAKALSMEEGRYGITAN 181 Query: 688 CVA 696 CVA Sbjct: 182 CVA 184 >UniRef50_Q39A64 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Burkholderia sp. 383|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 257 Score = 99.1 bits (236), Expect = 9e-20 Identities = 63/183 (34%), Positives = 95/183 (51%), Gaps = 1/183 (0%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 R +GKVA+VT + GIG +IA R +EGASVV + + + L +G+ V Sbjct: 8 RLAGKVAVVTGAASGIGRSIALRFANEGASVVATTSRNTAQLDETCRLAGDGVIVARQA- 66 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 + E L + +FG +D++ ++DT E WD + DVN+K +L Sbjct: 67 DAGSAEQVEALIDFVERRFGRLDVMCNNAGVIREAR-LVDTTEADWDAVMDVNLKGVFLG 125 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPL-GAYGVSKTTLLGLTKAIANETVHENIRV 684 K A P +++ GGGSIV + S +++ EPL AY SK +L LT+ +A E + IR Sbjct: 126 CKYAIPAMIRAGGGSIVNLGSTSSF-VGEPLHAAYCASKGGVLMLTRCVAIEHAKDRIRA 184 Query: 685 NCV 693 N V Sbjct: 185 NAV 187 >UniRef50_Q0VQZ0 Cluster: Oxidoreductase; n=4; Gammaproteobacteria|Rep: Oxidoreductase - Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) Length = 256 Score = 99.1 bits (236), Expect = 9e-20 Identities = 55/181 (30%), Positives = 90/181 (49%) Frame = +1 Query: 151 FSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCH 330 F+GK A++T + G G +A+ LG GA++V+ + +L +G+ V + C Sbjct: 7 FTGKTALITGAASGFGKLLAQELGKRGAALVLGDINMDALNPLADTLAEQGVKVAALRCD 66 Query: 331 VANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLA 510 V++ + + + A S+FG +D+ E+V D+ +VNVK Sbjct: 67 VSSEADCKAMVDAALSQFGHLDLAVNNAGIAHGFIPFTQLSEEVLDQQMNVNVKGVMFGM 126 Query: 511 KEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNC 690 K + +K GGGSIV +SS+A +GAY +K ++GLT+ A E NIRVN Sbjct: 127 KHQI-DAMKVGGGSIVNVSSMAGLGGAPKIGAYSAAKHAVIGLTRTAAVEYAKRNIRVNA 185 Query: 691 V 693 + Sbjct: 186 I 186 >UniRef50_O61709 Cluster: Putative uncharacterized protein; n=4; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 253 Score = 99.1 bits (236), Expect = 9e-20 Identities = 53/176 (30%), Positives = 89/176 (50%) Frame = +1 Query: 166 AIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHE 345 A+V +T +G A+ +RL G V + ++VGK + G V VAN E Sbjct: 4 ALVIGATSTLGKAVVRRLAFTGYKVAAAADCPNSVGKVAEDNIKVGGDVTAFSLDVANAE 63 Query: 346 HRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKEAYP 525 HR+ L K GG+D L I++T + +DK+F N+ + + L++ A Sbjct: 64 HRKELITKVAEKLGGLDTLIIVPPQNEVLGEIIETSGEDFDKLFANNLTTPFRLSQAAMS 123 Query: 526 ELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 L K GSI++++S + P+ +G Y V+ +++L LTK++A + +RVN V Sbjct: 124 TLAKSQNGSIIYLTSCFGFTPSIDMGLYSVASSSVLSLTKSVAQSAAKQGVRVNSV 179 >UniRef50_Q08632 Cluster: Short-chain type dehydrogenase/reductase; n=9; Spermatophyta|Rep: Short-chain type dehydrogenase/reductase - Picea abies (Norway spruce) (Picea excelsa) Length = 271 Score = 99.1 bits (236), Expect = 9e-20 Identities = 65/188 (34%), Positives = 92/188 (48%), Gaps = 8/188 (4%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSL-----RSEGITVEGV 321 G+VAIVT ++ GIG IA + +GA VVI + + V S+ S G V + Sbjct: 21 GRVAIVTGASRGIGREIALNMAEKGAKVVIHYSSNQHAAEEVASIINNKSPSSGDGVRAI 80 Query: 322 VCH--VANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXIL-DTDEQVWDKIFDVNVK 492 VC VA +LF+ A FG + I+ L T ++ WD+IF VN K Sbjct: 81 VCKADVAEPSQVAQLFDTAEHAFGPLHIVVNNAGVTDSKYPTLAQTSDEEWDRIFQVNCK 140 Query: 493 SSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHE 672 ++L ++EA +V+ GGG I+ ISS P GAY SK + +T+ +A E Sbjct: 141 GAFLCSREAAKRVVRGGGGRIINISSSLVAMPIPRYGAYTASKAAVEMMTRILAQELRGT 200 Query: 673 NIRVNCVA 696 I NCVA Sbjct: 201 QITANCVA 208 >UniRef50_Q1ASB7 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain dehydrogenase/reductase SDR - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 235 Score = 98.7 bits (235), Expect = 1e-19 Identities = 58/179 (32%), Positives = 91/179 (50%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVA 336 GKVA+VT +++G+G A+A GA + I +R+E ++ + + G V V V+ Sbjct: 4 GKVALVTGASQGLGRALALAYAQAGARLAINARREESIRPVAEEIARAGAQVLAVAADVS 63 Query: 337 NHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKE 516 E R A +FG +DIL I++ E+ W ++ DVN+ ++L++K Sbjct: 64 RSEDVGRFVGEAVERFGRIDILVNNAGLLGPRVPIVEYPEEEWRRVIDVNLTGAFLVSKA 123 Query: 517 AYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 A P + G SI+ + S + + GAY VSK L GLT+ +A E IRVN V Sbjct: 124 AIPHMPP--GSSIINVVSGVSVEGRPRWGAYSVSKFGLEGLTQILAAELKDRGIRVNAV 180 >UniRef50_A0HIJ6 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Comamonas testosteroni KF-1 Length = 258 Score = 98.7 bits (235), Expect = 1e-19 Identities = 56/180 (31%), Positives = 94/180 (52%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVA 336 GKVA+VT +T G+G AI + L ++GAS++ C R + + LR+ + +A Sbjct: 10 GKVALVTGATGGLGAAICRVLAAQGASILACDRDSDACQRMAEELRNGQGQALALPADLA 69 Query: 337 NHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKE 516 + L + A + G VDIL + D + W ++ D+N+++S L++ Sbjct: 70 DIPGITTLVQKALAWKGQVDILVCNAGIQGPAGSLSDIGDIDWQQVMDINLRASVELSRH 129 Query: 517 AYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVA 696 P + GGGS++ +SSIA + + +G YG+SK L L + +A E + IRVN V+ Sbjct: 130 LLPAMALAGGGSVILMSSIAGIRGNKAIGLYGLSKAALAQLARNLAVEWGPQAIRVNAVS 189 >UniRef50_Q9PCQ2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=11; Bacteria|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Xylella fastidiosa Length = 255 Score = 98.3 bits (234), Expect = 2e-19 Identities = 54/181 (29%), Positives = 89/181 (49%) Frame = +1 Query: 151 FSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCH 330 F G+VA+VT + G+G A A+ GASVV+ R + ++ +EG T G+ C Sbjct: 7 FKGQVALVTGAAAGMGLATARGFAQGGASVVLADRDGERAAQEAAAIVAEGGTAIGLACD 66 Query: 331 VANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLA 510 V++ L E +++G +D + + +D++ +N++ WL Sbjct: 67 VSDEAQVAALVEKTVAEYGRLDFAFNNAGVMAKIAPFAEATSEEFDRVIGINLRGVWLCM 126 Query: 511 KEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNC 690 K ++ ++G G IV +S+ A +GAY SK +LGLT+A A E + IRVN Sbjct: 127 KYELQQMQRQGSGVIVNNASVGALTGNVGIGAYIASKHGVLGLTRAAALEYCKKGIRVNA 186 Query: 691 V 693 V Sbjct: 187 V 187 >UniRef50_Q89JB0 Cluster: Bll5373 protein; n=4; Bacteria|Rep: Bll5373 protein - Bradyrhizobium japonicum Length = 262 Score = 98.3 bits (234), Expect = 2e-19 Identities = 66/180 (36%), Positives = 90/180 (50%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 SGK A+VT ST GIG+AIA+ L + GASVVI R + V AV+ L + G V G+ V Sbjct: 6 SGKTALVTGSTAGIGHAIARGLAASGASVVINGRGQDKVDAAVRKLEAAGGKVRGIAADV 65 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 + + L S VDIL D ++ W + F+VNV S L++ Sbjct: 66 STAAGCKAL----VSALPEVDIL-INNAGIFEPKDFFDIPDEDWSRFFEVNVMSGVRLSR 120 Query: 514 EAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 E ++KR G IVFISS + + YGVSKT L + + +A T + VN V Sbjct: 121 EYLKGMLKRNWGRIVFISSESGLNIPVEMIHYGVSKTAQLSVARGLAQLTRGTGVTVNSV 180 >UniRef50_Q0RIJ2 Cluster: Putative short chain dehydrogenase/reductase; n=1; Frankia alni ACN14a|Rep: Putative short chain dehydrogenase/reductase - Frankia alni (strain ACN14a) Length = 261 Score = 98.3 bits (234), Expect = 2e-19 Identities = 65/187 (34%), Positives = 91/187 (48%), Gaps = 4/187 (2%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 RF G+VA +T G G A A+ L GAS+V+ + ++ +L G V V C Sbjct: 13 RFDGRVAFITGGAAGFGLAFARELAERGASIVLADIDAAAAERSAAALTEAGHPVLPVRC 72 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXI----LDTDEQVWDKIFDVNVKS 495 VA + A +FGG+DIL + L D+ ++FDVNV Sbjct: 73 DVAAEDTVDAAVAAAVERFGGIDILVNNAGRHLTRYNLPFQTLARDDV--RELFDVNVMG 130 Query: 496 SWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHEN 675 + A P + RGGGSI+ ISS+A++ T P Y VSK + GLT A A E +N Sbjct: 131 VVNCSLAARPSMAARGGGSIINISSMASHLGTSP---YAVSKLAVRGLTVAFATEFAPDN 187 Query: 676 IRVNCVA 696 IRVN ++ Sbjct: 188 IRVNAIS 194 >UniRef50_A0GVX4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Burkholderia phytofirmans PsJN|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia phytofirmans PsJN Length = 259 Score = 98.3 bits (234), Expect = 2e-19 Identities = 56/181 (30%), Positives = 94/181 (51%), Gaps = 1/181 (0%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRS-EGITVEGVVCH 330 +GKVAIV ++GIG+ IA+ L +EGA VVI +R+E ++ +A +R G V + Sbjct: 6 TGKVAIVGGGSQGIGFGIARTLAAEGAQVVISARREEDLKRAAYEIRELTGNAVTWIAAD 65 Query: 331 VANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLA 510 E R+ +A ++FGG+DIL +L D+ W + + N+ + Sbjct: 66 CRKAEDCERVATIARAEFGGIDIL-VNNDGAPPVGPVLSFDDAAWHRAVEQNLMYPVRMV 124 Query: 511 KEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNC 690 ++ + +RGGGSI+ I++I+A QP LG + ++G K ++ E I VN Sbjct: 125 RQVADSMKERGGGSILNITAISAIQPIRDLGLSVATWGGVIGYAKTLSMELAEFGINVNT 184 Query: 691 V 693 + Sbjct: 185 I 185 >UniRef50_Q21BL9 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Rhodopseudomonas palustris BisB18|Rep: Short-chain dehydrogenase/reductase SDR - Rhodopseudomonas palustris (strain BisB18) Length = 252 Score = 97.9 bits (233), Expect = 2e-19 Identities = 59/180 (32%), Positives = 91/180 (50%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 R GK+AIVT S+ GIG A+ EGA+VV+ +R+E+ + + + G E +V Sbjct: 3 RLKGKIAIVTGSSSGIGKTTAEVFAREGATVVLVARRENRLSDLRAGIEANGGEAEYIVA 62 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 +A ++ + +KFG +DIL T +++WD + V++ S + L Sbjct: 63 DLALRSECEKVVDDVIAKFGRIDILVNNAGIPDRHMPTSRTSDELWDSVIAVDLTSVFYL 122 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 + + +RG GSIV ISSI A AY +K LL LT+ IA + +NIR N Sbjct: 123 CRATLKHMEERGSGSIVNISSIGARGLAG--AAYSSAKAGLLSLTRNIAIQYAGKNIRCN 180 >UniRef50_Q1ARQ7 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain dehydrogenase/reductase SDR - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 251 Score = 97.9 bits (233), Expect = 2e-19 Identities = 61/183 (33%), Positives = 95/183 (51%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 R GK IVT + GIG AIA R +EGA V + E K + EG V+ Sbjct: 3 RLEGKRTIVTGAGSGIGRAIALRFAAEGARVALADVDEGAARKVAAEI-GEGCLVQRTDV 61 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 VA E L +AT ++GG++++ T E+ ++++ VN++ ++L Sbjct: 62 TVA--EEVEGLVRLATERWGGLEVMVNNAGVGVAATAP-QTSEEDFERVLAVNLRGTFLG 118 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 K A P + GGG+++ +SSIAA + AY +K +L LT+A A + +HE +RVN Sbjct: 119 MKYAIPAIRDSGGGAVINMSSIAALVGLKDRAAYSAAKGGILALTRAGAIDHIHEGVRVN 178 Query: 688 CVA 696 C+A Sbjct: 179 CIA 181 >UniRef50_A1SC90 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=2; Nocardioides sp. JS614|Rep: Short-chain dehydrogenase/reductase SDR precursor - Nocardioides sp. (strain BAA-499 / JS614) Length = 258 Score = 97.5 bits (232), Expect = 3e-19 Identities = 55/186 (29%), Positives = 94/186 (50%) Frame = +1 Query: 136 IQSTRFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVE 315 ++STRF KVA++T + GIG A A+ L SEGA+V + + + + V ++ G Sbjct: 1 MKSTRFDNKVAVITGAGSGIGRAAAELLASEGAAVGVLDLRAESAEETVAAIVDSGGRAI 60 Query: 316 GVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKS 495 + +VA+ +++GG+++L TDE W++ F VN K Sbjct: 61 ALAANVADSAEVEAAIAKVVAEYGGLNVLYNNAGCDSRGSVADATDED-WERAFSVNAKG 119 Query: 496 SWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHEN 675 +++ ++ A P L GGG+IV S+AA AY +K ++ LT+++A + Sbjct: 120 TFVCSRAAVPHLTASGGGAIVNQGSVAALVGVPNFAAYCAAKGAVVALTRSMAIDLAPRK 179 Query: 676 IRVNCV 693 IRVN + Sbjct: 180 IRVNVI 185 >UniRef50_A0VRR7 Cluster: Short-chain dehydrogenase/reductase SDR; n=4; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Dinoroseobacter shibae DFL 12 Length = 303 Score = 97.5 bits (232), Expect = 3e-19 Identities = 55/180 (30%), Positives = 94/180 (52%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVA 336 GK A++T ++ GIG +A LG GA V++ +R+ + ++LR+EGI + V Sbjct: 63 GKRALITGASSGIGAHLALTLGQAGAEVILAARRADRLEAVAETLRAEGIVAQTAALDVT 122 Query: 337 NHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKE 516 + A + G +DIL ++DT E WD++ D N+K +W +++ Sbjct: 123 D----AASVAAAVTTVGPLDIL-INNSGVSGQDMVIDTTEADWDRVLDTNLKGAWRVSRA 177 Query: 517 AYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVA 696 P L+ R G+I+ ++SI + +G Y SK L+ LT+A+A E + +RVN +A Sbjct: 178 FAPGLIAR-QGTILNVASILGIGVLKTVGPYAASKAGLIQLTRAMALELARDGVRVNALA 236 >UniRef50_Q39TK3 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210) Length = 255 Score = 97.1 bits (231), Expect = 4e-19 Identities = 55/185 (29%), Positives = 98/185 (52%), Gaps = 2/185 (1%) Frame = +1 Query: 148 RFS--GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGV 321 RFS GK AIVT +++G+G A+A L GA++V+ SR E+++ K + S+G+ V Sbjct: 5 RFSLKGKTAIVTGASQGLGEAMALGLAEAGANLVLASRNEASMAKVASEVTSKGVQCLTV 64 Query: 322 VCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSW 501 + + + + + ++FG +DIL + T+E WD + D N+K + Sbjct: 65 KTDMLKADDIQAMVDKGIAQFGTIDILVNNAGINLVKPFVNLTEED-WDSVVDTNLKGYF 123 Query: 502 LLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIR 681 L ++ E++K G ++ +S+ + + +Y SK ++ LT+ +A E NIR Sbjct: 124 LCSQVVGREMIKNKNGCVINNASVFGLRGFPNIASYIASKGGVVQLTRGLAVEWARHNIR 183 Query: 682 VNCVA 696 VNC+A Sbjct: 184 VNCIA 188 >UniRef50_Q2I772 Cluster: PlaU; n=2; Streptomyces|Rep: PlaU - Streptomyces sp. Tu6071 Length = 244 Score = 97.1 bits (231), Expect = 4e-19 Identities = 57/180 (31%), Positives = 86/180 (47%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 +G A+VT T GIG A A GA V + R E + V+++ G + + + Sbjct: 2 AGVKALVTGGTSGIGLATAMAFAGRGADVAVTGRDEQRGRQVVKAIAEAGGVADFIAAEL 61 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 RRL + A ++FG +D+L T+ +D +F +NV+ + L Sbjct: 62 RGESSARRLAQAAVARFGRIDVLVNNAGVFPFGPTERTTEAD-FDAVFGLNVRVPYFLVA 120 Query: 514 EAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 E P + +RG G+IV +++ AA LG YG SK L+ LTKA A E +RVN V Sbjct: 121 ELAPAMARRGHGAIVNVTTAAAAYGAAGLGLYGASKAALVLLTKAWAAEYGPRGVRVNAV 180 >UniRef50_Q0SD55 Cluster: Possible short chain oxidoreductase; n=7; Actinomycetales|Rep: Possible short chain oxidoreductase - Rhodococcus sp. (strain RHA1) Length = 252 Score = 97.1 bits (231), Expect = 4e-19 Identities = 61/183 (33%), Positives = 97/183 (53%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 RF GK AIVT ++ GIG AIA+RL ++GA VVI +RK+ + +AV L + + V Sbjct: 4 RFEGKTAIVTGASRGIGLAIAERLVADGARVVITARKKEALDEAVTHLGGPDVAL-AVAG 62 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 + +H+ A FG +D L ++D D KI +VN ++ Sbjct: 63 RADDADHQGDAVRQAVETFGSIDFLVNNTGINPVYGSLVDLDLAAARKIVEVNCIAALSW 122 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 ++ + +K GG+IV +SS+++ + +G YG SK L LT+ +A E + +IR+N Sbjct: 123 VQQVHKAWMKEHGGAIVNVSSLSSIRTAPGIGFYGASKAMLNSLTELMAVE-LGPDIRIN 181 Query: 688 CVA 696 VA Sbjct: 182 GVA 184 >UniRef50_A7AZH2 Cluster: Putative uncharacterized protein; n=1; Ruminococcus gnavus ATCC 29149|Rep: Putative uncharacterized protein - Ruminococcus gnavus ATCC 29149 Length = 276 Score = 97.1 bits (231), Expect = 4e-19 Identities = 55/182 (30%), Positives = 90/182 (49%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 RF K+ +VT +T GIG A+A R EGA+VV R E V ++ G E + C Sbjct: 10 RFDEKIMLVTGATSGIGRAVAIRAAKEGATVVAVGRNEERGAAVVAAMEEAGGKGEFMKC 69 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 V+N + + LF K+G +D+ + + ++ W ++ D N+ S + Sbjct: 70 DVSNKDAVKALFAEIQEKYGKLDVAVNNAGIVGASKTVEELEDDDWFQVIDANLNSCFFC 129 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 +E +L++ GG+IV +SS+A + AY SK + GLTKA+A + + I N Sbjct: 130 CREEV-KLMQPSGGAIVNVSSVAGMRGFPSAAAYVASKHAVSGLTKAVAVDYATKGITCN 188 Query: 688 CV 693 + Sbjct: 189 AI 190 >UniRef50_A3D6S9 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Shewanella baltica OS155|Rep: Short-chain dehydrogenase/reductase SDR - Shewanella baltica OS155 Length = 251 Score = 97.1 bits (231), Expect = 4e-19 Identities = 60/184 (32%), Positives = 88/184 (47%), Gaps = 1/184 (0%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVG-KAVQSLRSEGITVEGVV 324 R +GKVA++T ++ GIG IA+ EGA ++I R + + V L++ G V + Sbjct: 3 RLTGKVALITGASRGIGAGIAEAFAIEGADLIINYRTNDDAAFRVVSKLKNLGRKVVAIR 62 Query: 325 CHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWL 504 V+ + L +A +FG +DIL TDE WD I N+K ++ Sbjct: 63 ADVSKRSEIQNLIHLAQIEFGRIDILVNNAGINQRGWFNEVTDE-AWDMIMGTNLKGPFM 121 Query: 505 LAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRV 684 +E +P + GGG I+ ISS+A Y VSK L LTK +A N+ V Sbjct: 122 CCQEVFPLMKANGGGRIINISSVAGQYHGPKTVHYAVSKAGLNSLTKVLARYGAEYNVLV 181 Query: 685 NCVA 696 N VA Sbjct: 182 NAVA 185 >UniRef50_A0X2N7 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=3; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR precursor - Shewanella pealeana ATCC 700345 Length = 262 Score = 97.1 bits (231), Expect = 4e-19 Identities = 60/187 (32%), Positives = 89/187 (47%) Frame = +1 Query: 133 AIQSTRFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITV 312 +I R GKVA +T + GIG A A RL +EGA V+IC R + + V ++ G Sbjct: 5 SINHARLLGKVAFITGAGSGIGAATAVRLAAEGAKVMICGRNQPPLDLVVAQIKQAGGVA 64 Query: 313 EGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVK 492 V+ V+N E S++G +DI+ I + D Q W + F +V Sbjct: 65 TAVIADVSNETELVAAIERCASEYGSLDIM-VNNAMAFTWGSIEEMDTQAWHENFKTSVD 123 Query: 493 SSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHE 672 ++ K A +L+K GGSI+ +SSI T + Y +K + ++A A E Sbjct: 124 GTFWGTKAAM-KLMKSNGGSIINLSSICGELGTPWMSGYSAAKAAVTNFSRAAAAEGAAS 182 Query: 673 NIRVNCV 693 NIRVN V Sbjct: 183 NIRVNTV 189 >UniRef50_Q12HD3 Cluster: Short-chain dehydrogenase/reductase SDR; n=28; cellular organisms|Rep: Short-chain dehydrogenase/reductase SDR - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 253 Score = 96.7 bits (230), Expect = 5e-19 Identities = 57/182 (31%), Positives = 88/182 (48%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 + +VAI+T + G G IAK GA VV+ + + ++ S G V Sbjct: 3 KLQDRVAIITGAGGGFGEGIAKHFAELGAKVVVADLRAEAAQQVAAAIESAGGQAIAVHV 62 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 V + A +FG +DIL +L+TDE+ +D+++ NVKS +L Sbjct: 63 DVTQDASVADMVAAAVKRFGRLDILVNNAGTTHKNQPMLETDEKTFDRVYATNVKSIYLG 122 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 A+ A P ++GGG I+ I+S A +P L Y +K + LTKA+A E + IRVN Sbjct: 123 ARHAVPLFRQQGGGVIINIASTAGLRPRPGLSWYAGTKGAAITLTKAMAVELAPDKIRVN 182 Query: 688 CV 693 + Sbjct: 183 AI 184 >UniRef50_Q029B5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Solibacter usitatus Ellin6076|Rep: Short-chain dehydrogenase/reductase SDR - Solibacter usitatus (strain Ellin6076) Length = 252 Score = 96.7 bits (230), Expect = 5e-19 Identities = 55/178 (30%), Positives = 86/178 (48%) Frame = +1 Query: 160 KVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVAN 339 +VA++T GIG A+A+ +GA V I R QS+ ++G + V + Sbjct: 10 RVALITGGATGIGEAVARLFACQGAHVHILDRDVEGCNSVAQSICADGGSAVASGGDVCS 69 Query: 340 HEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKEA 519 +R E A + G +DIL L EQ WD + D N+KS + + Sbjct: 70 TNDVQRWVEGAAQRSGRIDILINNAGIYPRQQ-FLGMSEQQWDAMQDTNLKSMFRTLQAV 128 Query: 520 YPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 P +VKRG G +V ISS+ + P+ Y SK ++GLT+++A E N+ +NC+ Sbjct: 129 LPHMVKRGSGKVVNISSVTFHLGMAPMSHYVTSKGGVIGLTRSLAREMGGHNVHINCI 186 >UniRef50_A5CFS4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; uncultured marine microorganism|Rep: Short-chain dehydrogenase/reductase SDR - uncultured marine microorganism Length = 203 Score = 96.3 bits (229), Expect = 6e-19 Identities = 56/182 (30%), Positives = 82/182 (45%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 R GKVAI+T +T GIG A A+ +GA V++ +R + + + L G + + Sbjct: 6 RLEGKVAIITGATGGIGEATARLYLDQGAKVMLVARSQEKLTALTKKLGG-GENIAQAIA 64 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 N + + FGGVDIL I + + W ++ +VNV WL Sbjct: 65 EADNEQQTANAVQATIDAFGGVDILMANAGTEGLVSPIENQTYENWQQVLNVNVIGVWLS 124 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 K + RGGGS++ ISS+A + Y SK + GL K A E IRVN Sbjct: 125 MKYCVAPMKARGGGSMIAISSVAGMTGFPGVSPYTASKHAVFGLVKTSAMELAESRIRVN 184 Query: 688 CV 693 + Sbjct: 185 AI 186 >UniRef50_Q8YCL4 Cluster: 3-OXOACYL-(ACYL-CARRIER PROTEIN) REDUCTASE; n=6; Brucellaceae|Rep: 3-OXOACYL-(ACYL-CARRIER PROTEIN) REDUCTASE - Brucella melitensis Length = 249 Score = 96.3 bits (229), Expect = 6e-19 Identities = 56/182 (30%), Positives = 88/182 (48%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 R KVAI+T + G G +A+R +EGA VV+ V + + S GI+++ Sbjct: 3 RLQDKVAIITGAGSGFGLGMARRFAAEGARVVLADVNVKRVEDGLADISSNGISIQA--- 59 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 V+ R+ A +FG +DI+ + D DE +D I VN+K+ + Sbjct: 60 DVSRKNDMERVARTAFEEFGRIDIMVNNAGFTHRNMPLTDVDEHNFDLIVAVNMKALYYS 119 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 + P + +GGG I+ +S P + L Y SK+ ++ TKA+A E NIRVN Sbjct: 120 TQLVVPIMEHQGGGVIINTASATGLHPRKGLTWYCASKSWVVSATKAMALELAERNIRVN 179 Query: 688 CV 693 C+ Sbjct: 180 CL 181 >UniRef50_Q6LH36 Cluster: Hypothetical oxidoreductase, short-chain dehydrogenase/reductase family; n=1; Photobacterium profundum|Rep: Hypothetical oxidoreductase, short-chain dehydrogenase/reductase family - Photobacterium profundum (Photobacterium sp. (strain SS9)) Length = 255 Score = 96.3 bits (229), Expect = 6e-19 Identities = 51/181 (28%), Positives = 94/181 (51%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 +GKVA+++ T GIG A A+ +GAS+V+ +R E+ + L ++ T+ + + Sbjct: 8 AGKVALISGITSGIGEATARLFSQQGASLVLVARNENKGQMLAEELNAQYPTLF-IKADI 66 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 ++FE ++FGG+D I +T +++W++I + N+ +W + Sbjct: 67 TQANQVDQVFEQTMAEFGGIDCAFNNAGIDGSKQPISETSDEIWNQIINTNLNGTWNMLN 126 Query: 514 EAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 + K+G G+IV ++SI + AY S+ +LGLT++ A E + +RVN V Sbjct: 127 RQLSIMSKQGHGTIVNMASICSVLARPNRAAYNTSRHAVLGLTRSAAVEYAKQGVRVNAV 186 Query: 694 A 696 A Sbjct: 187 A 187 >UniRef50_Q3E0W7 Cluster: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR; n=2; Chloroflexus|Rep: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR - Chloroflexus aurantiacus J-10-fl Length = 272 Score = 96.3 bits (229), Expect = 6e-19 Identities = 53/175 (30%), Positives = 87/175 (49%), Gaps = 1/175 (0%) Frame = +1 Query: 166 AIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANHE 345 A+VT + GIG AIA+ L GA V+I S +N+ +A ++L++ G+ V G+ C VAN Sbjct: 13 AVVTGGSRGIGRAIAEALARAGAQVIISSTNPTNLTEAERALQAAGLNVTGIRCDVANRN 72 Query: 346 HRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKEAYP 525 L A + G +D+ LD W+++ VN+ ++ + A P Sbjct: 73 EVEALASAAVERMGRIDLWVNNAGISGPFGYALDIPPDAWEQVIRVNLLGTYYGCRAALP 132 Query: 526 ELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANE-TVHENIRVN 687 ++K+ G I+ +S A + L AY SK ++ LT+A A + H +R N Sbjct: 133 YMIKQRNGQIINLSGGGAKRAQRFLSAYSTSKAAIVRLTEAFARDYQDHPYLRFN 187 >UniRef50_Q15TE7 Cluster: Short-chain dehydrogenase/reductase SDR; n=8; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Pseudoalteromonas atlantica (strain T6c / BAA-1087) Length = 266 Score = 96.3 bits (229), Expect = 6e-19 Identities = 60/182 (32%), Positives = 90/182 (49%), Gaps = 2/182 (1%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVA 336 GKVA+VT +T G A+ +G+ G ++++ + + +SLR EGI V + Sbjct: 16 GKVALVTGATGAFGQVAARVIGNSGCNLLLTGGNKEALESLAESLRQEGIHVATRNTRPS 75 Query: 337 NHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKE 516 + + E A S +G +DIL I D + W K+ D NV+ SWLL K Sbjct: 76 TEQECDAMVEQAVSTYGKLDIL-VVGSGVNDVDPIQDLSTERWQKVMDANVRDSWLLCKA 134 Query: 517 AYPELVKRGGGSIVFISSIAAYQPTEPLG--AYGVSKTTLLGLTKAIANETVHENIRVNC 690 A + + +GGG V + S A + P G AY SK+ + GLT+A+ E NI VN Sbjct: 135 AGKQFMSQGGGGKVVLVSSARGKLGHPAGYSAYCPSKSAVDGLTRALGCEWGKHNITVNA 194 Query: 691 VA 696 +A Sbjct: 195 IA 196 >UniRef50_A7DQI5 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: Short-chain dehydrogenase/reductase SDR precursor - Candidatus Nitrosopumilus maritimus SCM1 Length = 269 Score = 96.3 bits (229), Expect = 6e-19 Identities = 64/183 (34%), Positives = 93/183 (50%), Gaps = 3/183 (1%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 SGKVA+VT + GIG+A AK L GA+V I + V + ++ + SE +V V Sbjct: 26 SGKVALVTGGSRGIGFATAKVLSENGANVAITGK----VQERLEKVSSEISNSFAIVADV 81 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 E + + KFG +DIL + + D++ W+++ DVN+ + + K Sbjct: 82 RKTEDVKNAIKKIVEKFGRLDILVNNAGVFPKIKKLHEIDDEEWNEVLDVNLTGQFRVTK 141 Query: 514 EAYPELVKRGGGSIVFISS---IAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRV 684 EA P L K GSI+ ISS + AYQ AY +K L+ LTK A E + IRV Sbjct: 142 EAIPHLQKT-SGSIINISSDAGLKAYQGFN-ADAYSATKAALIVLTKCWALEYSKDKIRV 199 Query: 685 NCV 693 NC+ Sbjct: 200 NCI 202 >UniRef50_Q8CUW5 Cluster: 3-oxoacyl-(Acyl carrier protein) reductase; n=9; Firmicutes|Rep: 3-oxoacyl-(Acyl carrier protein) reductase - Oceanobacillus iheyensis Length = 253 Score = 95.9 bits (228), Expect = 8e-19 Identities = 53/183 (28%), Positives = 82/183 (44%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 + KVAIVT + G+G AIA SEGA V++ E V+ + S + Sbjct: 2 KLKDKVAIVTGAASGMGKAIATLYASEGAKVIVADLNEEGAQSVVEEITSNNGVATAIKV 61 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 ++A E ++ + A +G +DIL + D ++ WD IFD+N K Sbjct: 62 NIAQKEDIDKMIDTAVDTYGTLDILVNNAGIMDGFEAVGDVEDDRWDLIFDINTKGVMRA 121 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 ++A P +++ G IV +S AYG SK ++GLTK + IR N Sbjct: 122 MRKAIPIFLEKESGVIVNTASTGGLNGAHAGAAYGASKHAVIGLTKNTGYMYANSGIRCN 181 Query: 688 CVA 696 +A Sbjct: 182 AIA 184 >UniRef50_Q2G8A5 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=2; Sphingomonadaceae|Rep: Short-chain dehydrogenase/reductase SDR precursor - Novosphingobium aromaticivorans (strain DSM 12444) Length = 266 Score = 95.9 bits (228), Expect = 8e-19 Identities = 57/185 (30%), Positives = 89/185 (48%), Gaps = 4/185 (2%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 R GKV IVT S G+G A A + +G VV+ S + V+++R+E + C Sbjct: 4 RLDGKVCIVTGSGSGMGRASAMEMARQGGRVVVTDINTSAGEETVEAIRAEKGDAIFIAC 63 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXX----ILDTDEQVWDKIFDVNVKS 495 ++ + L + FGG+D+L I D E++WD +++VN+K+ Sbjct: 64 NLRKAHEIKVLMQKTADHFGGIDVLHNNAAIHETDLTDKTSIEDLPEEIWDAVYEVNLKA 123 Query: 496 SWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHEN 675 WL + A P L G +IV ++S ++ GAY +K +L LTKA A + Sbjct: 124 LWLTTRYAVPWLKLSKGAAIVNVASTGSFVSYPQAGAYCATKGGVLLLTKATAVDLAKYG 183 Query: 676 IRVNC 690 IR NC Sbjct: 184 IRCNC 188 >UniRef50_A3Z051 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Synechococcus sp. WH 5701|Rep: Short-chain dehydrogenase/reductase SDR - Synechococcus sp. WH 5701 Length = 256 Score = 95.9 bits (228), Expect = 8e-19 Identities = 58/182 (31%), Positives = 95/182 (52%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 R GK A+++ ++G+G AIA+R GA + + R +G+ + + + Sbjct: 5 RLDGKRALISGGSKGLGAAIAERFSEAGADIGVIGRDREGLGRIQGIVENNHRNCWVIEE 64 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 V++ E RR + A + D+L IL+T + W+ IF VN++S+ LL Sbjct: 65 DVSSIEGARRAGDKALALDPEWDVLVNNAGIARVQS-ILETTQDNWNDIFSVNLRSALLL 123 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 ++ P+++KRG G +V ISSI A+ T LGAY SK L LT+ +A E N++VN Sbjct: 124 SQAIVPQMIKRGHGKVVNISSIGAFIGTPGLGAYAASKAALNQLTRTMAVEWGPHNVQVN 183 Query: 688 CV 693 + Sbjct: 184 AL 185 >UniRef50_Q81RT0 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family; n=19; Bacteria|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family - Bacillus anthracis Length = 242 Score = 95.5 bits (227), Expect = 1e-18 Identities = 54/179 (30%), Positives = 87/179 (48%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVA 336 GK A++T + GIG A+A L EG +V + +R E N+ + + +EG+ V+ Sbjct: 10 GKNALITGAGRGIGRAVAIALAKEGVNVGLLARSEENLKAVAKEVEAEGVKAVIATADVS 69 Query: 337 NHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKE 516 ++E E + G +DIL L+ D W+KI VN+ + + Sbjct: 70 SYEEVTTAIETLKNGLGSIDILINNAGISKFGK-FLELDVADWEKIIQVNLMGVYYATRA 128 Query: 517 AYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 A P ++++ G I+ ISS A + AY SK +LGLT+++A E NIRV + Sbjct: 129 ALPSMIEQQSGDIINISSTAGQKGAPVTSAYSASKFGVLGLTESLAMEVRKHNIRVTAL 187 >UniRef50_Q3WFP9 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Frankia sp. EAN1pec|Rep: Short-chain dehydrogenase/reductase SDR - Frankia sp. EAN1pec Length = 262 Score = 95.5 bits (227), Expect = 1e-18 Identities = 61/182 (33%), Positives = 87/182 (47%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 R KVA++T + GIG AIA R +EGASVV S G+AV G GV Sbjct: 2 RLKDKVAVITGAGSGIGKAIAHRFAAEGASVVCASVS----GRAVDVAAEIGDGALGVKA 57 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 V++ RR+ A FG +DIL I + + WD++ VN++ + Sbjct: 58 DVSDEADVRRMIGAAEEAFGRIDILVNNAGFGGKLKPIHEQSTEDWDRVHGVNLRGVFFC 117 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 K + + GGGS+V +SS A + G YG +K + LT+ A + +NIRVN Sbjct: 118 MKYGIMSMRRTGGGSVVNVSSTTAVIGWKHHGIYGAAKAGVNQLTRVAALDYADDNIRVN 177 Query: 688 CV 693 V Sbjct: 178 AV 179 >UniRef50_Q2VQT1 Cluster: Ketoacyl ACP/CoA reductase-like protein; n=2; Streptomyces|Rep: Ketoacyl ACP/CoA reductase-like protein - Streptomyces natalensis Length = 257 Score = 95.5 bits (227), Expect = 1e-18 Identities = 60/183 (32%), Positives = 89/183 (48%), Gaps = 2/183 (1%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 SGKV+++T ++ GIG A A+ EGA+VV+ +R+ + V +R G + V Sbjct: 9 SGKVSLITGASSGIGAATARLFAREGAAVVLAARRVDRLRALVSEIRRTGAEAAYIATDV 68 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 + E RR E K+G +D+ + + +D + NV+ W + Sbjct: 69 SQEEDVRRAVEFTVEKYGRLDLAFNNAGVGCDHESMHLMQQDTYDDVMGTNVRGVWHCLQ 128 Query: 514 EAYPELVKRG-GGSIVFISSIAAYQPTEPLGA-YGVSKTTLLGLTKAIANETVHENIRVN 687 ++ G GGSIV SS+A Q P GA Y SK ++GLTKA A E + IRVN Sbjct: 129 HEISAMLHNGVGGSIVNNSSVAGLQAI-PAGAPYIASKHAVIGLTKAAAAEYAPQGIRVN 187 Query: 688 CVA 696 VA Sbjct: 188 SVA 190 >UniRef50_A1SNH6 Cluster: Short-chain dehydrogenase/reductase SDR; n=4; Actinomycetales|Rep: Short-chain dehydrogenase/reductase SDR - Nocardioides sp. (strain BAA-499 / JS614) Length = 250 Score = 95.5 bits (227), Expect = 1e-18 Identities = 63/184 (34%), Positives = 96/184 (52%), Gaps = 3/184 (1%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSL--RSEGITVEGVVC 327 +GKVAIVT ++ GIG IA+RL EGA V + +RK+ + AV+SL I V G Sbjct: 5 AGKVAIVTGASRGIGLGIAQRLVDEGAKVCVTARKQEALDAAVESLGGAEHAIAVAGKAD 64 Query: 328 HVANHEHR-RRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWL 504 A+ E RR E FG +D+L ++D D KI +VN + Sbjct: 65 DPAHREDAVRRTIET----FGSLDLLVNNAGINPVLAHLVDIDLDAARKIVEVNALGALA 120 Query: 505 LAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRV 684 + A+ + GG++V ISS++ +P + YG SK ++ LT+++A E + ++RV Sbjct: 121 WVQSAHRAWMAEHGGAVVNISSVSGVRPAPGIAMYGASKAMMISLTESLAVE-LGPSVRV 179 Query: 685 NCVA 696 N VA Sbjct: 180 NAVA 183 >UniRef50_Q5L166 Cluster: Oxidoreductase; n=8; Bacteria|Rep: Oxidoreductase - Geobacillus kaustophilus Length = 260 Score = 95.1 bits (226), Expect = 1e-18 Identities = 59/188 (31%), Positives = 92/188 (48%), Gaps = 5/188 (2%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 + GK AIVT G+G IA L GA+VV+CSRK + + L G+ + C Sbjct: 8 KIEGKTAIVTGGGRGLGEQIAVGLAEAGANVVVCSRKVEACEQVKEKLEQLGVRSLALRC 67 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 V N E + + E +FGG+DIL + + + W K+ +VNV ++L+ Sbjct: 68 DVTNPEEVKHVVETTVKEFGGIDIL-VNNSGATWGAPVEEMPLEAWQKVINVNVTGTFLM 126 Query: 508 AKEAYPELV-KRGGGSIVFISSIAAYQPTEP----LGAYGVSKTTLLGLTKAIANETVHE 672 ++ ++ K+ GGSI+ I+S+A T P Y SK ++ T+ +A + Sbjct: 127 SQAVGKVMIAKQTGGSIINIASVAGLGGTHPDILNTIGYNTSKGAVITFTRDLAAKWGKH 186 Query: 673 NIRVNCVA 696 IRVN VA Sbjct: 187 GIRVNAVA 194 >UniRef50_Q126E9 Cluster: Short-chain dehydrogenase/reductase SDR; n=42; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 256 Score = 95.1 bits (226), Expect = 1e-18 Identities = 56/181 (30%), Positives = 92/181 (50%), Gaps = 1/181 (0%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVA 336 G+ +VT + G+G++ A+ L GA VV+ +E + ++V +LR+EG GV V Sbjct: 12 GRRILVTGAARGLGFSFARTLCESGARVVLADLREELLQQSVATLRAEGFDASGVAVDVG 71 Query: 337 NHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQV-WDKIFDVNVKSSWLLAK 513 + + E A + GG+D L +D E WD++ +VNV+ +WL+ + Sbjct: 72 DPASIQCCAEQAVANLGGLDGLVNNAAVTDSGGRGMDDIEIAKWDQVMNVNVRGTWLMTR 131 Query: 514 EAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 P L G G+IV ++S A L AY SK ++ +T ++A E +NI VN + Sbjct: 132 ACRPALRAGGRGAIVNLASDTAMWGAPNLLAYVASKGAVIAMTHSLARELGPDNITVNAI 191 Query: 694 A 696 A Sbjct: 192 A 192 >UniRef50_A3WIC9 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein; n=3; Proteobacteria|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein - Erythrobacter sp. NAP1 Length = 267 Score = 95.1 bits (226), Expect = 1e-18 Identities = 62/186 (33%), Positives = 93/186 (50%), Gaps = 4/186 (2%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSE-GITVEGVV 324 RF+GK I+T S+ GIG IA+R +EGA+VVI +R K +L ++ +T G Sbjct: 6 RFAGKTVIITGSSAGIGEGIARRFHAEGANVVINARNAEKCAKVADTLDADRTLTCPG-- 63 Query: 325 CHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWL 504 V++ + + +FGG+D L + TD++ D+I D+NVK Sbjct: 64 -DVSSSDFANEIVAKTVERFGGLDCL-VNNAGVGGSSMLHKTDDEEIDRIIDINVKGVIY 121 Query: 505 LAKEAYPELVKR---GGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHEN 675 L + A P L K GGGSI+ ISS++ L Y SK + LT+ +A + Sbjct: 122 LCRAAIPHLRKSEAVGGGSIINISSVSGIGGDSMLPIYNASKGAMTNLTRGLAQQIGGMG 181 Query: 676 IRVNCV 693 IRVN + Sbjct: 182 IRVNAI 187 >UniRef50_A3I0R2 Cluster: Short chain dehydrogenase; n=2; Bacteroidetes|Rep: Short chain dehydrogenase - Algoriphagus sp. PR1 Length = 252 Score = 95.1 bits (226), Expect = 1e-18 Identities = 61/180 (33%), Positives = 90/180 (50%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 R GK AI+T +T G+G AIAKR EGA +++ R + N + +SL G V Sbjct: 2 RLKGKTAIITGATSGMGKAIAKRFSEEGAFLILSGRNQENGIELERSLNEAGGKAVFVKG 61 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 V E L + A S FG +DI+ + + W + + N + + L Sbjct: 62 DVGIIETNEALVKAAISNFGKLDIV-VTNAGKLGLGSVTEISLAEWQETMNTNFNAVFFL 120 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 ++ A PE++K GGG+I+ SSIAA++ AY SK L+ L K +A + NIRVN Sbjct: 121 SRFAIPEMIKSGGGTILANSSIAAFKSFPNHAAYCASKAALVALVKEMAVD-YGPNIRVN 179 >UniRef50_A1CGP4 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family; n=8; Pezizomycotina|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family - Aspergillus clavatus Length = 328 Score = 95.1 bits (226), Expect = 1e-18 Identities = 60/202 (29%), Positives = 99/202 (49%), Gaps = 3/202 (1%) Frame = +1 Query: 97 SLNISTSANPVRAIQST-RFSGKVAIVTASTEGIGYAIAKRLGSEGAS--VVICSRKESN 267 S I T N + ++ + +GK AI+T GIG A+A EGAS +V +ES+ Sbjct: 63 STRIPTDDNGYQTYKAAGKLAGKRAIITGGDSGIGRAVAILFAMEGASSLIVYLPDEESD 122 Query: 268 VGKAVQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILD 447 + + ++ G + + E+ R++ +VA GGVD+L I + Sbjct: 123 AQETKRRVQEIGKECHCLAIDLRKKENCRKVVDVALQYMGGVDVLVNNAAFQHMVQDISE 182 Query: 448 TDEQVWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTT 627 DE W++ FD N+ + LAK P + R G +I+ SS+ Y L Y +K Sbjct: 183 LDEAQWERTFDTNIHPFFYLAKYTLPHM--RSGSTIINCSSVNHYIGRSDLLDYTSTKGA 240 Query: 628 LLGLTKAIANETVHENIRVNCV 693 ++ T+A++N+ + + IRVNCV Sbjct: 241 IVAFTRALSNQQIGKGIRVNCV 262 >UniRef50_A7DM07 Cluster: Short-chain dehydrogenase/reductase SDR; n=4; Alphaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Methylobacterium extorquens PA1 Length = 282 Score = 94.7 bits (225), Expect = 2e-18 Identities = 55/182 (30%), Positives = 85/182 (46%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 RF+GKVA +T + GIG A A EGA V I R E + + + G V + C Sbjct: 37 RFNGKVAFITGAASGIGRAAAIAFAREGAQVAITDRTEEALERLRAEIEGNGGAVIAIRC 96 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 V+ E +FG +D + + WD+I D+N++ +++ Sbjct: 97 DVSLPEDVAAAVARTVERFGRLDCAFNNAGVENKAAPVHEIALDEWDRILDINLRGTFVC 156 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 K +++++GGG +V SS A + +Y SK L+GLTK+ A + NIRVN Sbjct: 157 MKHEIAQMLRQGGGVVVNTSSGAGIRGVAGGASYAASKHALIGLTKSAALDYAKANIRVN 216 Query: 688 CV 693 V Sbjct: 217 AV 218 >UniRef50_A3ZQM3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=1; Blastopirellula marina DSM 3645|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Blastopirellula marina DSM 3645 Length = 258 Score = 94.7 bits (225), Expect = 2e-18 Identities = 59/182 (32%), Positives = 91/182 (50%), Gaps = 1/182 (0%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSE-GITVEGVVCH 330 SG+ A+VT ++GIG AIA+ L GASV I +R + + A Q + + + V +C Sbjct: 10 SGRTALVTGGSKGIGKAIARGLAEAGASVCITARHQQELETAAQEIGAGLDVRVAWRICD 69 Query: 331 VANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLA 510 +A+ L + +FG VDIL + TDE WD + ++N S LA Sbjct: 70 MADRAAVDALADGVLEEFGQVDILFNNAGTNQPQLLVETTDES-WDHVLEINFTSCMRLA 128 Query: 511 KEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNC 690 ++ P +++R G I+ +SS+ A G Y +K L +T+A A E I VNC Sbjct: 129 RKLAPGMIERRWGRIIHLSSVLAVVSNPGRGNYSGTKGALSAMTRAHALELGPHGITVNC 188 Query: 691 VA 696 +A Sbjct: 189 LA 190 >UniRef50_Q9HLN6 Cluster: Probable glucose 1-dehydrogenase; n=4; cellular organisms|Rep: Probable glucose 1-dehydrogenase - Thermoplasma acidophilum Length = 268 Score = 94.7 bits (225), Expect = 2e-18 Identities = 58/182 (31%), Positives = 89/182 (48%), Gaps = 1/182 (0%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKA-VQSLRSEGITVEGVVCH 330 +GK+A+VT S+ G+G AIAK + GA V + R + A V ++++G Sbjct: 14 TGKIALVTGSSSGLGAAIAKYMARAGAKVAVHYRSGKDRADAIVDEIKNDGGFAMAFYGD 73 Query: 331 VANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLA 510 V+ E ++LF SK G VDIL + + D W+K+ +VN+ + A Sbjct: 74 VSKKEDVQKLFSEIDSKLGTVDILVNNAGIDGKRELVGEDDPDDWEKVIEVNLMGPYYCA 133 Query: 511 KEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNC 690 +EA + + G I+ I+S+ Y P AY +K L TKA+A E NIRV Sbjct: 134 REAVKRMKPKKSGVIINITSVHEYVPWSGYTAYSSAKAGLSMFTKALAQELSDYNIRVVA 193 Query: 691 VA 696 +A Sbjct: 194 IA 195 >UniRef50_Q987X7 Cluster: Probable short-chain dehydrogenase; n=1; Mesorhizobium loti|Rep: Probable short-chain dehydrogenase - Rhizobium loti (Mesorhizobium loti) Length = 261 Score = 94.3 bits (224), Expect = 3e-18 Identities = 55/182 (30%), Positives = 90/182 (49%) Frame = +1 Query: 151 FSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCH 330 F KVA++T +T GI A A+RL GA+++ C + +SL G Sbjct: 4 FENKVALITGTT-GIALATARRLAQGGAAIIACGIDRAANAAMQESLAKAGADALVQTVD 62 Query: 331 VANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLA 510 V+ + R +KFGG+D++ TD + W++ VNV S +L A Sbjct: 63 VSISDQVRDAVVAGVAKFGGIDVIVNSAAVHPYGTATT-TDWETWNRAMSVNVGSIYLTA 121 Query: 511 KEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNC 690 PE++KRGGG+IV ++S+ + + + AY +K + LT+++A + IRVN Sbjct: 122 HFGIPEMIKRGGGAIVNVASVQGFACQQNVAAYATTKGAIHTLTRSLALDYAAAGIRVNS 181 Query: 691 VA 696 V+ Sbjct: 182 VS 183 >UniRef50_Q1GNJ7 Cluster: Short-chain dehydrogenase/reductase SDR; n=23; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Sphingopyxis alaskensis (Sphingomonas alaskensis) Length = 258 Score = 94.3 bits (224), Expect = 3e-18 Identities = 57/185 (30%), Positives = 97/185 (52%), Gaps = 4/185 (2%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRS---EGITVEGVV 324 +G+VA++T S+ GIG A A+ + +GA VVI SRK+ + + EG + V Sbjct: 7 TGQVALITGSSRGIGKATAEAMAEQGAKVVISSRKQDACDATAAEINARFGEGTAI-AVA 65 Query: 325 CHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSS-W 501 ++++ + + L + FG + L L ++ + KI D N+ S+ W Sbjct: 66 ANISSKDDLQNLVNETRAAFGKITALVCNAASNPYYGPGLGISDEQFRKIMDNNILSNHW 125 Query: 502 LLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIR 681 L++ A PE+++RG GSI ISSI + + +GAYG+SK + + + + E +R Sbjct: 126 LISMVA-PEMLERGDGSITIISSIGGLKGSPIIGAYGISKAADMQVARNFSVEFGPRGVR 184 Query: 682 VNCVA 696 VNC+A Sbjct: 185 VNCIA 189 >UniRef50_A3Q331 Cluster: Short-chain dehydrogenase/reductase SDR; n=10; Mycobacterium|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium sp. (strain JLS) Length = 282 Score = 94.3 bits (224), Expect = 3e-18 Identities = 59/181 (32%), Positives = 91/181 (50%), Gaps = 1/181 (0%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVA 336 G+VAIVT GIG +A+R +EGA VVI ++ +G+A+ V Sbjct: 11 GRVAIVTGGASGIGRGVAERFVAEGAKVVIADVQDE-LGEALAEQCGPNALFHHT--DVG 67 Query: 337 NHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXX-ILDTDEQVWDKIFDVNVKSSWLLAK 513 + E RRL +VA +FG +D++ + + D + +D++ VN+ S + Sbjct: 68 DQEQMRRLVDVAVERFGALDVMVNNAGISSPLRRGLFNEDLEEFDRVMRVNLLSVMAGTR 127 Query: 514 EAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 +A + + GGGSI+ +SSI Q + Y SK +L TK A E H +IRVNC+ Sbjct: 128 DAGRYMSEHGGGSIINLSSIGGIQAGGGVPVYRASKAAILHFTKCAAIELAHYDIRVNCI 187 Query: 694 A 696 A Sbjct: 188 A 188 >UniRef50_A3Q0B5 Cluster: Short-chain dehydrogenase/reductase SDR; n=7; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium sp. (strain JLS) Length = 255 Score = 94.3 bits (224), Expect = 3e-18 Identities = 59/183 (32%), Positives = 86/183 (46%), Gaps = 2/183 (1%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 +G+ A+VT +G+G A A L GA+V I R K V+ +EG + + + Sbjct: 10 TGRTALVTGGNQGLGRAFAFGLAQAGATVAISGRSAERNAKVVEEAAAEGFALHPITADI 69 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 + R+ A S G +DIL D E+ WD +FD+NVK+ W + Sbjct: 70 TRQDDVDRMTAEAISALGHLDILVNNAGTCYHAES-WDVTEEQWDSVFDLNVKALWACSL 128 Query: 514 EAYPELVKRGGGSIVFISSIAAYQPTEP--LGAYGVSKTTLLGLTKAIANETVHENIRVN 687 A + +RG GSIV I S++ P AY SK + LTK++A E IRVN Sbjct: 129 AAGAHMRERGSGSIVNIGSMSGLIVNRPQMQPAYNASKAAVHHLTKSLAAEWGPLGIRVN 188 Query: 688 CVA 696 +A Sbjct: 189 ALA 191 >UniRef50_A3I4P3 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Bacillus sp. B14905|Rep: Short-chain dehydrogenase/reductase SDR - Bacillus sp. B14905 Length = 260 Score = 94.3 bits (224), Expect = 3e-18 Identities = 61/180 (33%), Positives = 91/180 (50%), Gaps = 1/180 (0%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSE-GITVEGVVCHV 333 GKVAI+T S++GIGY A +L EGA VV+C+R E + A +++E G+ V V + Sbjct: 7 GKVAIITGSSKGIGYYTAMQLVKEGAQVVLCARGEKQLQVAAGCIKNETGVDVLIVPTDI 66 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 + + L E FG VDIL ++W D+ V + +K Sbjct: 67 TKEKDCKNLIERTVEHFGHVDIL-INNAGTASANPFETVSSELWQADLDLKVFGAIHCSK 125 Query: 514 EAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 A P + K GGG+IV ++++ A P VS+ L LTKA++ + +NIRVN V Sbjct: 126 YAAPYMRKAGGGAIVNVTAVMAKTPPASSLPTTVSRAAGLALTKAMSKDLGKDNIRVNSV 185 >UniRef50_A2U8H9 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Bacillus coagulans 36D1|Rep: Short-chain dehydrogenase/reductase SDR - Bacillus coagulans 36D1 Length = 262 Score = 94.3 bits (224), Expect = 3e-18 Identities = 55/186 (29%), Positives = 89/186 (47%) Frame = +1 Query: 136 IQSTRFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVE 315 +Q+ F+GKVAIVT GIG +L + GA+VV+ + + +R G Sbjct: 1 MQTFDFTGKVAIVTGGGGGIGREACLKLAAGGANVVVADLSDELGEETAGKIRENGGEAI 60 Query: 316 GVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKS 495 V V+ + + A +G +DIL ++D E+V+DK+ +NV+ Sbjct: 61 FVRTDVSKSKDVQHYVRTALDTYGKIDILLNNAGWEGKMKPLIDYPEEVFDKLMGINVRG 120 Query: 496 SWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHEN 675 +L K P ++ + G+IV +S+A T + AYG SK ++G+TK E Sbjct: 121 VFLGMKYVLPHMISQKSGTIVNTASVAGLVGTPEMVAYGASKHAVIGMTKTAGIEAAPSG 180 Query: 676 IRVNCV 693 +RVN V Sbjct: 181 VRVNAV 186 >UniRef50_A1ULZ8 Cluster: Short-chain dehydrogenase/reductase SDR; n=18; Corynebacterineae|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium sp. (strain KMS) Length = 253 Score = 94.3 bits (224), Expect = 3e-18 Identities = 59/184 (32%), Positives = 91/184 (49%), Gaps = 2/184 (1%) Frame = +1 Query: 151 FSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCH 330 F KVAIVT + GIG A A+ L EGA+VV+ K ++ EG V Sbjct: 8 FKDKVAIVTGAGGGIGQAYAEALAREGAAVVVADINVDGAQKVADGIKGEGGNALAVRVD 67 Query: 331 VANHEHRRRLFEVATSKFGGVDIL--XXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWL 504 V++ + + + S+FGG+D L ++ D + K VN+ + + Sbjct: 68 VSDPDSAKEMAAQTLSEFGGIDYLVNNAAIFGGMKLDFLITVDWDYYKKFMSVNLDGALV 127 Query: 505 LAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRV 684 + Y ++ KRGGG+IV SS AA+ + YG++K + GLT+ +A E +NIRV Sbjct: 128 CTRAVYRKMAKRGGGAIVNQSSTAAWLYS---NFYGLAKVGINGLTQQLATELGGQNIRV 184 Query: 685 NCVA 696 N +A Sbjct: 185 NAIA 188 >UniRef50_Q3EBS2 Cluster: Uncharacterized protein At2g29340.1; n=5; core eudicotyledons|Rep: Uncharacterized protein At2g29340.1 - Arabidopsis thaliana (Mouse-ear cress) Length = 307 Score = 94.3 bits (224), Expect = 3e-18 Identities = 57/181 (31%), Positives = 91/181 (50%), Gaps = 1/181 (0%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVA 336 G A+VT GIGYAI + L GA + +C E+ + +++ +G V G VC VA Sbjct: 9 GMTALVTGGASGIGYAIVEELAGFGARIHVCDISEAKLNQSLSEWEKKGFQVSGSVCDVA 68 Query: 337 NHEHRRRLFEVATSKFGG-VDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 + R L + +S+F G ++IL T++ I NV++++ ++ Sbjct: 69 SRPEREELMQTVSSQFDGKLNILVSNVGVIRSKPTTEYTEDDFAFHI-SSNVEAAYHFSQ 127 Query: 514 EAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 ++P L G GSI+F+SSIA + YG++K L+ L K +A E + IR N V Sbjct: 128 LSHPLLKASGYGSIIFVSSIAGVISFDAGSIYGLTKGALIQLAKNLACEWAKDGIRANAV 187 Query: 694 A 696 A Sbjct: 188 A 188 >UniRef50_UPI000045C1E7 Cluster: COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); n=1; Nostoc punctiforme PCC 73102|Rep: COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - Nostoc punctiforme PCC 73102 Length = 247 Score = 93.9 bits (223), Expect = 3e-18 Identities = 57/183 (31%), Positives = 87/183 (47%) Frame = +1 Query: 139 QSTRFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEG 318 ++ ++GKVA VT + GIG A A EGA+VV+ E + V+ + G V Sbjct: 5 ENGNYTGKVAFVTGAANGIGRATALAFAREGANVVVADVSEQGNQETVRLIEDLGGRVLA 64 Query: 319 VVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSS 498 V C V E FG +D + +E WD+I + +++S Sbjct: 65 VKCDVTRTEDVTAALSKTIETFGRLDFAFNNAGVEQKKAATAELEEAEWDRIVNTDLRSV 124 Query: 499 WLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENI 678 +L K P ++K+GGG+IV SS A + AY +K ++GLTKA A + +NI Sbjct: 125 FLCLKHEIPLMLKQGGGAIVNTSSGAGVIGIKGGAAYTAAKHGVIGLTKAAALDYASQNI 184 Query: 679 RVN 687 R+N Sbjct: 185 RIN 187 >UniRef50_Q8F0K8 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=4; Leptospira|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Leptospira interrogans Length = 259 Score = 93.9 bits (223), Expect = 3e-18 Identities = 63/192 (32%), Positives = 90/192 (46%), Gaps = 3/192 (1%) Frame = +1 Query: 127 VRAIQSTRFSGKVAIVT--ASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSE 300 +R I S +F GKVA+VT AS G+G AIA + EG +V+ + + +A + E Sbjct: 1 MREIMSKQFEGKVALVTGAASPRGLGRAIANTIAKEGGDIVLVDLNKEQIEQAAADVAKE 60 Query: 301 -GITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIF 477 G+ G+ C+V E + KFG +D L I EQ +D + Sbjct: 61 FGVKTLGLSCNVTKPEDCDSVIAGVKEKFGKLDFLVNNAGVLKDNLFIR-MSEQEFDFVL 119 Query: 478 DVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIAN 657 DVN+K +L+ K A L+K G IV ISS++ Y SK ++ LTK A Sbjct: 120 DVNLKGVFLMTKYASKLLLKAESGRIVNISSVSGLTGQPGQANYSSSKAGVIALTKVAAR 179 Query: 658 ETVHENIRVNCV 693 E N+ VN V Sbjct: 180 EFAGRNVLVNAV 191 >UniRef50_Q2SJ12 Cluster: Short-chain alcohol dehydrogenase-like protein; n=1; Hahella chejuensis KCTC 2396|Rep: Short-chain alcohol dehydrogenase-like protein - Hahella chejuensis (strain KCTC 2396) Length = 251 Score = 93.9 bits (223), Expect = 3e-18 Identities = 54/183 (29%), Positives = 84/183 (45%), Gaps = 1/183 (0%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 + GKV +VT ++ GIG A +L + GA V + +R+ V+ + G + Sbjct: 2 KLDGKVVMVTGASSGIGRTTAIKLANYGAKVAVIARRSRESEDTVRHITEAGGQAISIPA 61 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 V++ + FG +D + + EQ WD++F +N K +WL Sbjct: 62 DVSSESDIKNALAQIIETFGKLDGAFNNAGAAEPVGPLTELSEQEWDRVFSINTKGAWLC 121 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPT-EPLGAYGVSKTTLLGLTKAIANETVHENIRV 684 K P L+ G+IV +SSI T L AY SK ++GLTKA + E NIR+ Sbjct: 122 MKHQIPALLSNKSGAIVNMSSIYGLVGTGMGLAAYVASKHAIIGLTKAASLEYAARNIRI 181 Query: 685 NCV 693 N + Sbjct: 182 NAI 184 >UniRef50_Q1DAW1 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family; n=1; Myxococcus xanthus DK 1622|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family - Myxococcus xanthus (strain DK 1622) Length = 275 Score = 93.9 bits (223), Expect = 3e-18 Identities = 59/191 (30%), Positives = 97/191 (50%), Gaps = 1/191 (0%) Frame = +1 Query: 127 VRAIQSTR-FSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEG 303 VRA T+ F G+V ++T ++ GIG A+ + GA VV+ +R+ + A + + S G Sbjct: 2 VRAGMKTQPFKGRVVLITGASGGIGRTAARAYAAAGADVVLAARRLPELEDAAREVASLG 61 Query: 304 ITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDV 483 + V C V + RL + FGG+D+L +EQ+ ++F++ Sbjct: 62 VRALPVRCDVTVGDDVTRLVRETDAAFGGLDVLVNNAGQGLYGPLEGVGEEQL-RQVFEL 120 Query: 484 NVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANET 663 NV S W + +EA P L KR G +V +SS+ ++ LG Y SK + +T+++ E Sbjct: 121 NVFSLWRMTREALPLLRKRRGAQVVNVSSVLGHRGLPLLGGYCASKAAVNAMTESLRAEL 180 Query: 664 VHENIRVNCVA 696 E IRV V+ Sbjct: 181 AAEGIRVLLVS 191 >UniRef50_Q0SGL9 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=4; Actinomycetales|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Rhodococcus sp. (strain RHA1) Length = 260 Score = 93.9 bits (223), Expect = 3e-18 Identities = 57/181 (31%), Positives = 89/181 (49%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 +G+ AIVT ++ GIG A+AK + + G +VV+ SR + + A + G T G+ H Sbjct: 7 TGRTAIVTGASRGIGLAVAKAIAAAGGNVVLTSRSQESADAAAAQV---GGTAIGIAAHA 63 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 + E RR +V +FG +DIL ++D D + K FDVN+ + L Sbjct: 64 VDEEAARRCVDVTLERFGSLDILVNNAGTNPSFGPVIDQDHARFAKTFDVNLWAPVLWTG 123 Query: 514 EAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 + GG++V +SI +G Y SK L+ +TK +A E + +RVN V Sbjct: 124 LVTKAWMGEHGGAVVNTASIGGMAFEANIGLYNASKAALIHVTKQLALE-LSPKVRVNAV 182 Query: 694 A 696 A Sbjct: 183 A 183 >UniRef50_P94681 Cluster: Toluenesulfonate zinc-independent alcohol dehydrogenase TsaC; n=5; Proteobacteria|Rep: Toluenesulfonate zinc-independent alcohol dehydrogenase TsaC - Comamonas testosteroni (Pseudomonas testosteroni) Length = 252 Score = 93.9 bits (223), Expect = 3e-18 Identities = 52/178 (29%), Positives = 85/178 (47%) Frame = +1 Query: 160 KVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVAN 339 +VAIVT G G AIA+RL GA+V++ + L + G G+ C V+ Sbjct: 6 QVAIVTGGASGFGAAIARRLSQAGAAVLVADLNAEGAQRMATELNAAGGRALGMACDVSK 65 Query: 340 HEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKEA 519 R + + A ++ GG+ I+ L E +D+++ VN+KS + A+ A Sbjct: 66 EADYRAVVDAAIAQLGGLHIVVNNAGTTHRNKPALAVTEDEFDRVYRVNLKSVYWSAQCA 125 Query: 520 YPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 P ++G G +V ++S +P L Y SK ++ LTK +A E +R+N V Sbjct: 126 LPHFAQQGHGVMVNVASTTGVRPGPGLTWYSGSKAAMINLTKGLALEFARSGVRINAV 183 >UniRef50_A7HFH2 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Anaeromyxobacter sp. Fw109-5|Rep: Short-chain dehydrogenase/reductase SDR - Anaeromyxobacter sp. Fw109-5 Length = 276 Score = 93.9 bits (223), Expect = 3e-18 Identities = 56/182 (30%), Positives = 92/182 (50%) Frame = +1 Query: 151 FSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCH 330 F+GKVA+V ++ GIG A A+ + GA+V + +R + + V+S+R+EG + Sbjct: 12 FAGKVAMVAGASRGIGAATARAFAAAGAAVALAARDGAALNGVVESIRAEGGDAMAIPTD 71 Query: 331 VANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLA 510 V + L T FG +D + D D +D+ +V+ ++L Sbjct: 72 VGDAGAVAHLVAETTRVFGRLDAAFNNATDGPPPAPLADLDPDDFDRGIRADVRGTFLGM 131 Query: 511 KEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNC 690 K P +++ GGG+IV ++S+AA LGAY K+ ++GLT+ A + IRVN Sbjct: 132 KYEIPAMLRSGGGAIVNMASLAALYGFTGLGAYVAGKSGIIGLTRVAALDYADRGIRVNV 191 Query: 691 VA 696 VA Sbjct: 192 VA 193 >UniRef50_A6CL44 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reductase; n=1; Bacillus sp. SG-1|Rep: 3-oxoacyl-(Acyl-carrier-protein) reductase - Bacillus sp. SG-1 Length = 254 Score = 93.9 bits (223), Expect = 3e-18 Identities = 52/181 (28%), Positives = 90/181 (49%), Gaps = 1/181 (0%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 S KV ++T +++G+G +A EGA + IC+R E + + + L G V V V Sbjct: 15 SDKVVMITGASKGLGRELAFAFAKEGAKLAICARGEEKLKEVQRDLERIGAEVLAVAADV 74 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXIL-DTDEQVWDKIFDVNVKSSWLLA 510 +N R + +G VD+L +L D + ++ + VNV ++ ++ Sbjct: 75 SNQRDVDRFVSITEGVYGRVDVLINNASVFGKGPCLLLDYLNEEFEDVLRVNVMNTLMMT 134 Query: 511 KEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNC 690 K P ++ RGGGS++ ++S A GAYG+SK + G+T+ A+E +R+N Sbjct: 135 KRVLPGMLSRGGGSVINLTSEAGKTGFAEWGAYGISKFAVEGMTQTWADELSETGVRMNM 194 Query: 691 V 693 V Sbjct: 195 V 195 >UniRef50_A5FEZ2 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Bacteroidetes|Rep: Short-chain dehydrogenase/reductase SDR - Flavobacterium johnsoniae UW101 Length = 263 Score = 93.9 bits (223), Expect = 3e-18 Identities = 57/184 (30%), Positives = 93/184 (50%), Gaps = 2/184 (1%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSE--GITVEGV 321 + GK A ++ ST+GIG+AIAK+L +E A V+I R E AVQ L+ E V G+ Sbjct: 4 KLEGKKAFISGSTQGIGFAIAKQLLNEKAEVIINGRNEEKTNLAVQKLKDEFPNAAVSGI 63 Query: 322 VCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSW 501 VC N L ++ +DIL DE W +IF++NV SS Sbjct: 64 VCDFGNKAEVTALL----NQLNDIDILINNVGIFELKDFETIEDED-WYRIFEINVMSSV 118 Query: 502 LLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIR 681 L+K+ P+++++ G I+FISS + + YG++K ++ + ++ T+ + Sbjct: 119 KLSKKLLPQMLQKKSGRIIFISSESGVNIPGNMIHYGMTKAAMMAVGNGLSKLTLGTEVT 178 Query: 682 VNCV 693 VN + Sbjct: 179 VNTI 182 >UniRef50_A3VK91 Cluster: Putative 3-ketoacyl-CoA reductase; n=1; Rhodobacterales bacterium HTCC2654|Rep: Putative 3-ketoacyl-CoA reductase - Rhodobacterales bacterium HTCC2654 Length = 253 Score = 93.9 bits (223), Expect = 3e-18 Identities = 58/179 (32%), Positives = 84/179 (46%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVA 336 G A VT + GIG AIA L EG V IC+R E + + +EG+ G Sbjct: 7 GMKAAVTGGSRGIGKAIAMHLAQEGCDVSICARGEEGIAATRAEIEAEGVRSFGTALQGR 66 Query: 337 NHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKE 516 + + R FGG+D+L +E W + F+++V S+ E Sbjct: 67 DGDAVRGWMRETCDVFGGLDLLVCSLSGGGGT-----NEEGYWRRSFEIDVMSATRAVDE 121 Query: 517 AYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 AYP L K G GSI+ ISS+AA + AY K +L+ +K +A + + IRVNC+ Sbjct: 122 AYPHLKKSGKGSILVISSMAAAETFVSPMAYNAMKASLVTWSKQLAEQYAPKGIRVNCL 180 >UniRef50_A1K895 Cluster: Short-chain dehydrogenase family protein; n=16; Bacteria|Rep: Short-chain dehydrogenase family protein - Azoarcus sp. (strain BH72) Length = 264 Score = 93.9 bits (223), Expect = 3e-18 Identities = 63/182 (34%), Positives = 85/182 (46%), Gaps = 2/182 (1%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSE--GITVEGVVC 327 SGK A+VT ST GIGYAIA+RL +EGA VV+ R V A LR++ V G Sbjct: 6 SGKRALVTGSTAGIGYAIARRLAAEGAEVVVNGRDAGRVDAACARLRADLPAARVSGHAA 65 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 VAN L S VD+L D D+ W F+ NV S L Sbjct: 66 DVANASGVASLLAACDS----VDLLVNNFSLYVPRP-FEDIDDAEWQHFFEANVMSGVRL 120 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 A+ P + G G +VFISS + P + YG++K+ L +++ +A + VN Sbjct: 121 ARHYLPRMKAAGWGRVVFISSESGLNPPGDMVHYGMTKSAQLSISRGLAETCAGTGVTVN 180 Query: 688 CV 693 V Sbjct: 181 AV 182 >UniRef50_A0TW00 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Burkholderia cenocepacia MC0-3|Rep: Short-chain dehydrogenase/reductase SDR precursor - Burkholderia cenocepacia MC0-3 Length = 277 Score = 93.9 bits (223), Expect = 3e-18 Identities = 62/187 (33%), Positives = 86/187 (45%), Gaps = 4/187 (2%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 R GK+AIVT + GIG A A RL EGASVV+ + V+ + G Sbjct: 3 RVKGKIAIVTGAASGIGAACAARLAHEGASVVVADLNLEGAQEQVRHIADSGGHAVAARV 62 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXX----ILDTDEQVWDKIFDVNVKS 495 + + LF++ +GG+DIL I D VWD +N++ Sbjct: 63 DIGDECSIEALFDLTLKTWGGLDILHNNAAATSLSSTADAAIEAIDVAVWDDTMRINLRG 122 Query: 496 SWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHEN 675 + L ++ A P + RGGGSI+ SS AA AYGV K + LT+ IA + E Sbjct: 123 TMLASRRALPLMRSRGGGSIINTSSGAAQAGALGYSAYGVCKAGIENLTRYIAAQYGKEG 182 Query: 676 IRVNCVA 696 IR N +A Sbjct: 183 IRCNAIA 189 >UniRef50_A0TVV4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Burkholderia cenocepacia MC0-3|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia cenocepacia MC0-3 Length = 259 Score = 93.9 bits (223), Expect = 3e-18 Identities = 54/181 (29%), Positives = 87/181 (48%), Gaps = 2/181 (1%) Frame = +1 Query: 160 KVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSL--RSEGITVEGVVCHV 333 KVAIVT S+ GIGYA A + GA VVI R A Q++ R C++ Sbjct: 11 KVAIVTGSSRGIGYASALGMAEHGAKVVISGRNGDVCETAAQAINERIGSRAAMPFACNI 70 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 + L + A ++G VDI+ +LD ++ ++K VNV+S+ LA+ Sbjct: 71 GRKAELQNLVDAANGEWGRVDIVMANAAIHPWVGSVLDLQDETFNKFMQVNVQSNIWLAQ 130 Query: 514 EAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 P +++RG G + ++S+ G YG++K + L + +A E + I NC+ Sbjct: 131 MTMPGMIERGYGRFISVASVVGLFGDPVTGTYGLTKAADMQLVRNLATEFAAKGITANCI 190 Query: 694 A 696 A Sbjct: 191 A 191 >UniRef50_Q9WYS2 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=2; Thermotoga|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Thermotoga maritima Length = 255 Score = 93.5 bits (222), Expect = 4e-18 Identities = 58/183 (31%), Positives = 93/183 (50%), Gaps = 3/183 (1%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSE-GITVEGVVCHV 333 G+VA+VT + G+G+ IA+ L G SVV+ SR +A Q L + G+ C V Sbjct: 9 GRVALVTGGSRGLGFGIAQGLAEAGCSVVVASRNLEEASEAAQKLTEKYGVETMAFRCDV 68 Query: 334 ANHEHRRRLFEVATSKFGGVD-ILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLA 510 +N+E ++L E KFG +D ++ DE + ++ +VN+ ++ + Sbjct: 69 SNYEEVKKLLEAVKEKFGKLDTVVNAAGINRRHPAEEFPLDE--FRQVIEVNLFGTYYVC 126 Query: 511 KEAYPELVKRGGGSIVFISSIAAYQPTEP-LGAYGVSKTTLLGLTKAIANETVHENIRVN 687 +EA+ L + SI+ I S+ + T P + AY SK + LTKA+A E IRVN Sbjct: 127 REAFSLLRESDNPSIINIGSLTVEEVTMPNISAYAASKGGVASLTKALAKEWGRYGIRVN 186 Query: 688 CVA 696 +A Sbjct: 187 VIA 189 >UniRef50_Q88LI6 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=2; Bacteria|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Pseudomonas putida (strain KT2440) Length = 262 Score = 93.5 bits (222), Expect = 4e-18 Identities = 55/181 (30%), Positives = 87/181 (48%) Frame = +1 Query: 151 FSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCH 330 FSGKV +VT + GIG A A GASV + + K V+ +++EG Sbjct: 7 FSGKVVLVTGAGSGIGRATALAFAQSGASVAVADISTDHGLKTVELVKAEGGEATFFHVD 66 Query: 331 VANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLA 510 V + + + + +GG+DI + + D W ++ DVN+ S + Sbjct: 67 VGSEPSVQSMLAGVVAHYGGLDIAHNNAGIEANIVPLAELDSDNWRRVIDVNLSSVFYCL 126 Query: 511 KEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNC 690 K P ++KRGGG+IV +S + L Y +K ++GLTKA A + ++NIR+N Sbjct: 127 KGEIPLMLKRGGGAIVNTASASGLIGGYRLSGYTATKHGVVGLTKAAAIDYANQNIRINA 186 Query: 691 V 693 V Sbjct: 187 V 187 >UniRef50_O34782 Cluster: YvrD protein; n=3; Bacillus|Rep: YvrD protein - Bacillus subtilis Length = 263 Score = 93.5 bits (222), Expect = 4e-18 Identities = 54/178 (30%), Positives = 92/178 (51%) Frame = +1 Query: 160 KVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVAN 339 K+ ++T ST GIG A AK EGA+V++ RK+ V + ++ L G TV G ++ Sbjct: 8 KLVLITGSTSGIGKAAAKSFLQEGAAVIVNGRKQETVDRTIEELSGYG-TVHGAAADLSK 66 Query: 340 HEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKEA 519 + E ++ G +DIL TDE+ W++ F+VNV S+ ++ Sbjct: 67 TDEAAAFIE-KVNEIGDIDILVNNLGFFEVKDFADVTDEE-WNQYFEVNVMSAVRTSRHF 124 Query: 520 YPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 P+++ + G I+ I+S A +P + Y ++KT L+ L++ +A T N+ VN V Sbjct: 125 LPKMLAKNSGRILNIASEAGVKPLPTMIPYSMTKTALISLSRGMAEMTKGTNVTVNSV 182 >UniRef50_Q1YS84 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; gamma proteobacterium HTCC2207|Rep: Short-chain dehydrogenase/reductase SDR - gamma proteobacterium HTCC2207 Length = 255 Score = 93.5 bits (222), Expect = 4e-18 Identities = 59/181 (32%), Positives = 88/181 (48%), Gaps = 1/181 (0%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 SGKVA+VT ++ G G AK L + GA VV+ +R+ + V +++ G V V Sbjct: 8 SGKVAMVTGASSGFGVNFAKILAARGAKVVVAARRVDRLEALVAEIQAAGGEACAVAMDV 67 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 + E F+ + FG + ++ L DE WD + D N+K W++A+ Sbjct: 68 TSAESVTAAFDKGEAAFGTITVV-SNNAGVADGKSALKADEASWDWVVDTNLKGVWMVAQ 126 Query: 514 EAYPELVKRG-GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNC 690 EA +V G GGSIV +SI + Y SK ++ LTKA A E + IRVN Sbjct: 127 EAAKRMVAAGVGGSIVNTASILGLRVAFAQSVYSASKAGVIQLTKAQALEWGRKGIRVNA 186 Query: 691 V 693 + Sbjct: 187 L 187 >UniRef50_Q1NCY5 Cluster: Dehydrogenase; n=1; Sphingomonas sp. SKA58|Rep: Dehydrogenase - Sphingomonas sp. SKA58 Length = 258 Score = 93.5 bits (222), Expect = 4e-18 Identities = 61/186 (32%), Positives = 91/186 (48%), Gaps = 4/186 (2%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 R GKVAIVT GIG A+RLG EGA VVI R + + + S G + V Sbjct: 3 RLDGKVAIVTGGAAGIGAGTAERLGQEGAKVVIADRNIAGAEQVAHGI-SNGQAL-AVQF 60 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXX----ILDTDEQVWDKIFDVNVKS 495 + ++L A FG +DIL +LDT + D + +N++S Sbjct: 61 DATDEGSIQKLIATAKDHFGRIDILHNNVAMTAEAWSRDTNLLDTTVETLDLSYAINLRS 120 Query: 496 SWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHEN 675 ++ K A P ++ +GGGSI+ +SS + L AYG +K ++ LTK +A + N Sbjct: 121 MFIACKAALPIMIDQGGGSIINMSSGSGEAGAPTLIAYGTTKGGVITLTKYLAVQYGRAN 180 Query: 676 IRVNCV 693 +R NC+ Sbjct: 181 VRSNCI 186 >UniRef50_Q97SL2 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=55; root|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Streptococcus pneumoniae Length = 271 Score = 93.1 bits (221), Expect = 6e-18 Identities = 51/185 (27%), Positives = 95/185 (51%) Frame = +1 Query: 133 AIQSTRFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITV 312 +I+ GK+A++T ++ GIG+AIAK GA++V + V K +++ R GI Sbjct: 7 SIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVFNDINQDLVNKGIEAYREVGIQA 66 Query: 313 EGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVK 492 G VC V + + + + + + G +DIL + + + K+ D+++ Sbjct: 67 HGYVCDVTDEDGIQAMVKQIEQEVGVIDIL-VNNAGIIRRVPMCEMSAADFRKVIDIDLN 125 Query: 493 SSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHE 672 + ++++K P ++K+G G I+ I S+ + E + AY +K L LT+ IA+E Sbjct: 126 APFIVSKAVIPSMIKKGHGKIINICSMMSELGRETVSAYAAAKGGLKMLTRNIASEYGGA 185 Query: 673 NIRVN 687 NI+ N Sbjct: 186 NIQCN 190 >UniRef50_Q89E38 Cluster: Oxidoreductase; n=2; Proteobacteria|Rep: Oxidoreductase - Bradyrhizobium japonicum Length = 258 Score = 93.1 bits (221), Expect = 6e-18 Identities = 50/185 (27%), Positives = 89/185 (48%), Gaps = 2/185 (1%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGA-SVVICSRKESNVGKAVQSLRSEGITVEGVV 324 R G+V +VT GIG A A R+ SEGA +++I R+E+ + + R G + Sbjct: 10 RMRGRVCLVTGGGSGIGRATALRMASEGAEALIIAGRREAEIEATAAACREIGAAAIALK 69 Query: 325 CHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWL 504 + + RL +A + G +D+ + + +++D +FD NV++ +L Sbjct: 70 TDITREDDVARLVGIAVERCGRLDVAFNNAGFQERRAPLEEQGTEIYDSVFDTNVRALFL 129 Query: 505 LAKEAYPELVKRGGGSIVFISSIAAYQ-PTEPLGAYGVSKTTLLGLTKAIANETVHENIR 681 + P ++ +G GSIV +S++ + P Y SK + LT++ A E IR Sbjct: 130 CLRHQLPAMLAQGRGSIVVNASVSGVRNPNPGFSLYSASKAAAISLTRSAAMENAPRGIR 189 Query: 682 VNCVA 696 +N +A Sbjct: 190 INAIA 194 >UniRef50_Q1VR66 Cluster: 3-oxoacyl-[ACP] reductase; n=1; Psychroflexus torquis ATCC 700755|Rep: 3-oxoacyl-[ACP] reductase - Psychroflexus torquis ATCC 700755 Length = 251 Score = 93.1 bits (221), Expect = 6e-18 Identities = 53/183 (28%), Positives = 91/183 (49%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 + GK AI+T ++GIG +IA L EG ++ IC+R + + K L +G+ V C Sbjct: 4 QLKGKNAIITGGSKGIGKSIALHLAEEGVNIAICARGKEALQKTKNELLEKGVKVFTQTC 63 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 V + E ++FG VDIL + + Q W+ +++ +S Sbjct: 64 DVGDSEQFNLFLTAVKNEFGSVDIL-----VNNASALTMGDEYQDWEASLQIDLMASVRA 118 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 K+ P + + G G+I+FISS++ + P AY +K L+ +K +A + ++IRVN Sbjct: 119 TKKVVPWMSESGSGNILFISSVSGLESGSP-PAYAAAKAALISYSKTMAVQLAPQHIRVN 177 Query: 688 CVA 696 +A Sbjct: 178 TIA 180 >UniRef50_Q4A054 Cluster: Uncharacterized oxidoreductase SSP0419; n=15; Staphylococcus|Rep: Uncharacterized oxidoreductase SSP0419 - Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 /DSM 20229) Length = 234 Score = 93.1 bits (221), Expect = 6e-18 Identities = 50/180 (27%), Positives = 90/180 (50%), Gaps = 1/180 (0%) Frame = +1 Query: 160 KVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLR-SEGITVEGVVCHVA 336 KVA+VT ++ GIG +IA+ L ++G VV+ R ES + + + ++ ++ VE + V Sbjct: 7 KVAVVTGASSGIGASIAETLANQGVKVVLTGRDESRLAEVAKRIQDNKQAVVETSIVDVT 66 Query: 337 NHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKE 516 + E L E KFG +DIL I + D + W+ + DVN+K + Sbjct: 67 HKEEVTELVEKTKEKFGQIDILVNSAGLMLSSA-ITEGDVEAWEAMIDVNIKGTLYTINA 125 Query: 517 AYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVA 696 P ++ + G I+ I+SI+ ++ T+ Y SK + +T+ + E +RV ++ Sbjct: 126 VLPSMLNQSSGHIINIASISGFEVTKKSTLYSASKAAVHSITQGLEKELAKTGVRVTSIS 185 >UniRef50_Q9RUC2 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family; n=10; Bacteria|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family - Deinococcus radiodurans Length = 255 Score = 92.7 bits (220), Expect = 8e-18 Identities = 58/166 (34%), Positives = 85/166 (51%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 +GK A VT +++GIGYA+A+ L +EG V I SRK+ + +A Q L G V GVVC V Sbjct: 22 AGKSAFVTGASKGIGYAVAQALAAEGYRVTITSRKQGEIDEAAQQL---GENVRGVVCDV 78 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 + + + FG +D+L + EQ W + D N+ ++ K Sbjct: 79 KDAAAVQSAVDAHVEAFGSLDVLFVNAGVGHFANIEQLSIEQ-WQDVIDTNLSGAFYTIK 137 Query: 514 EAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAI 651 A P L K+ GG I+ +SS+A P E AY SK L GL++ + Sbjct: 138 AAIPAL-KKQGGYILTLSSLAGKNPFEGGAAYNASKFGLNGLSEVV 182 >UniRef50_Q8EMX3 Cluster: Hypothetical conserved protein; n=1; Oceanobacillus iheyensis|Rep: Hypothetical conserved protein - Oceanobacillus iheyensis Length = 254 Score = 92.7 bits (220), Expect = 8e-18 Identities = 58/180 (32%), Positives = 86/180 (47%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVA 336 GKV ++T GIG A AK L GA V + E ++ KA +SL E V + +V Sbjct: 3 GKVVLITGGAGGIGQATAKLLLDYGAKVALVDINEDSLVKAKESLHVEDDRVFTITGNVT 62 Query: 337 NHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKE 516 E + +FG +D+ I + D+ ++KI +NV +L K Sbjct: 63 VEEDVENYVKQTVDRFGKIDVFFNNAGVNGPVSPITELDQATFEKIMSINVTGVFLGLKH 122 Query: 517 AYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVA 696 ++ K+G GSIV +S AAY + + +Y SK + G+TK A E + IRVN VA Sbjct: 123 VMKQMKKQGYGSIVNTASNAAYIGSAGMVSYIASKHAVAGITKTAALEVASDGIRVNAVA 182 >UniRef50_Q62GI3 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family; n=26; Proteobacteria|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family - Burkholderia mallei (Pseudomonas mallei) Length = 265 Score = 92.7 bits (220), Expect = 8e-18 Identities = 58/181 (32%), Positives = 94/181 (51%) Frame = +1 Query: 151 FSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCH 330 F+ KVA++T GIG A+A++ G VV+ R+ + + L + I V G Sbjct: 4 FNDKVALITGGGTGIGAAVARKFVEAGGRVVLLGRRREPLDAVAKPLGAAAIAVAG---D 60 Query: 331 VANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLA 510 A+ RR + A + FG VD+L LDTD+ W + VN+ ++++ A Sbjct: 61 AADAHDVRRALDDARAAFGRVDVL-VANAGGHGVGSALDTDDASWAQSTRVNLDTAFVCA 119 Query: 511 KEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNC 690 +E PEL++R GSIV +SS+A + + Y +K L+GLT+++A + +RVN Sbjct: 120 RELLPELIER-RGSIVILSSLAGHFAGPNVIGYVTTKHALIGLTRSLARDYGRAGVRVNA 178 Query: 691 V 693 V Sbjct: 179 V 179 >UniRef50_Q1ARM4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain dehydrogenase/reductase SDR - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 252 Score = 92.7 bits (220), Expect = 8e-18 Identities = 55/179 (30%), Positives = 90/179 (50%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVA 336 GKVA++T GIG A A EGA V+I E + V+++R+ G C V+ Sbjct: 6 GKVALITGGATGIGRATALLFAREGACVLIGDINEEGASETVEAVRAAGGDAAFRRCDVS 65 Query: 337 NHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKE 516 E L A ++G +D++ + D + ++ +N+ +++LL K Sbjct: 66 GEEEIAALVAAAGEEYGRLDVVFGNAGLLRTRP-LEDLSTKEFELHLRINLTANFLLTKY 124 Query: 517 AYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 A P + + GGSI+F++S + T AY SK L+ +T+++A+E NIRVNCV Sbjct: 125 AAPVMRRHEGGSIIFMASAGGLRGTRGSVAYNASKGGLVNMTRSLADELAPHNIRVNCV 183 >UniRef50_Q143V4 Cluster: Putative dehydrogenase; n=1; Burkholderia xenovorans LB400|Rep: Putative dehydrogenase - Burkholderia xenovorans (strain LB400) Length = 281 Score = 92.7 bits (220), Expect = 8e-18 Identities = 60/179 (33%), Positives = 81/179 (45%) Frame = +1 Query: 160 KVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVAN 339 KVA +T + G+G IAKRL GASV + + L G TV V C+V + Sbjct: 10 KVAAITGAAGGLGTGIAKRLAGLGASVALLEPGIERLVSLASELTDSGATVLNVACNVTD 69 Query: 340 HEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKEA 519 R S FG +D+L + + WD+ VN+ + L Sbjct: 70 AASTRYAAAQVLSSFGRIDVLVNNAGVLARPSALESISLEDWDRSLAVNLTGALLCTASF 129 Query: 520 YPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVA 696 +++ G GSIV I+SIAAY P + AY VSK LL LT+ A E IR N V+ Sbjct: 130 GAAMLEAGAGSIVNIASIAAYSPNTSV-AYSVSKAGLLALTRHTAVEWAPRGIRANSVS 187 >UniRef50_Q12AF9 Cluster: Short-chain dehydrogenase/reductase SDR; n=22; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 267 Score = 92.7 bits (220), Expect = 8e-18 Identities = 57/198 (28%), Positives = 98/198 (49%), Gaps = 4/198 (2%) Frame = +1 Query: 112 TSANPVRAIQSTRFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSL 291 T++ P Q +GK A+VT + G+G +A+ LG GA V++ SRK ++ ++ L Sbjct: 2 TASKPRSIQQLFDLTGKTALVTGGSRGLGLQLAQALGEAGAKVILSSRKAEDLIESAAEL 61 Query: 292 RSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDK 471 ++ GI V+ + + E R L + A + G VDIL D + WDK Sbjct: 62 KAAGIDVDWIAADCSKEEDIRALADEAIKRLGHVDIL-VNNAGAAWGAPAEDHPVEAWDK 120 Query: 472 IFDVNVKSSWLLAKE-AYPELVKRGGGSIVFISSIAAY---QPTEPLGAYGVSKTTLLGL 639 + ++N++ ++L++ A ++ R G I+ ++SIA P AY SK ++ Sbjct: 121 VMNLNIRGYFILSQHIAKHSMIARKSGRIINVASIAGLGGNPPEMTTVAYNTSKGAVINF 180 Query: 640 TKAIANETVHENIRVNCV 693 T+A+ E NI VN + Sbjct: 181 TRALGCEWGKYNITVNAI 198 >UniRef50_A4Z1Y9 Cluster: Putative short-chain dehydrogenases/reductase; n=1; Bradyrhizobium sp. ORS278|Rep: Putative short-chain dehydrogenases/reductase - Bradyrhizobium sp. (strain ORS278) Length = 305 Score = 92.7 bits (220), Expect = 8e-18 Identities = 55/183 (30%), Positives = 91/183 (49%), Gaps = 1/183 (0%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQS-LRSEGITVEGVV 324 RF GK +VT +T GIG A A +GA+VV C R+E+ +G+ V++ +++EG + Sbjct: 50 RFGGKTVLVTGATSGIGRAAAIAFARQGAAVVFCGRREA-LGREVEAEIKAEGGRARFIR 108 Query: 325 CHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWL 504 V R L A + FGG+DI + + D W + D N++ + Sbjct: 109 ADVRVEAEMRDLVVQAIATFGGLDI-ALNNAGITIEKPLHELDAADWADVVDTNLRGVFF 167 Query: 505 LAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRV 684 K E++ RGGG+I+ SS ++ AY +K L+G+ ++ A + NIR+ Sbjct: 168 AMKYEIAEMLPRGGGTILVTSSSVVHRTGPRRSAYTATKAGLVGMVRSAALDYADNNIRI 227 Query: 685 NCV 693 N + Sbjct: 228 NAI 230 >UniRef50_A3XPW3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=3; Flavobacteriaceae|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Leeuwenhoekiella blandensis MED217 Length = 246 Score = 92.7 bits (220), Expect = 8e-18 Identities = 61/179 (34%), Positives = 89/179 (49%) Frame = +1 Query: 160 KVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVAN 339 + A+VT G+GYAIA++ G V I R E +A +L G V +V + N Sbjct: 4 QTAVVTGGNSGLGYAIARKFCDAGYKVYIIGRNEEKTRQAADNL---GELVVPIVFDLNN 60 Query: 340 HEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKEA 519 E +L + G +D+L TD + +D+I NVKS + +++E Sbjct: 61 LEAIPKLIDELLQATGKIDVLVNNAGINMKKDFAEVTDAE-FDRILHTNVKSVFAISREV 119 Query: 520 YPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVA 696 + GGSIV ISS+AA + AY SKT + G+T+A+A + NIRVNCVA Sbjct: 120 VKSMKGNYGGSIVNISSMAAQYGIPQVIAYTASKTAIEGMTRAMAVDLAQYNIRVNCVA 178 >UniRef50_A0JAB3 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Shewanella woodyi ATCC 51908|Rep: Short-chain dehydrogenase/reductase SDR precursor - Shewanella woodyi ATCC 51908 Length = 278 Score = 92.7 bits (220), Expect = 8e-18 Identities = 56/185 (30%), Positives = 98/185 (52%), Gaps = 6/185 (3%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSE-GITVEGVVCHV 333 GK+A++T + G+GYAIAK L S+G +++ +R E+ + +A L ++ G+ V V Sbjct: 8 GKLAVITGGSSGLGYAIAKELASKGFDLLLVARNEAQLKEASSKLIADSGVKVHTTSVDV 67 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 + E L E S DI+ ++DT WD++++VNV+ + K Sbjct: 68 SKEEDVLSLKETVRSLAPCADII-VNSAGIVSGGFLVDTPLAEWDRLYNVNVRGLVSVLK 126 Query: 514 EAYPELVKRGGGS-----IVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENI 678 P+++++GG IV I+S AAY T + AYG +K +L L++++A+E ++ Sbjct: 127 SLLPDMIEQGGSDGQERHIVNIASAAAYTATGGMSAYGSTKAGVLALSESLAHEVAPSHV 186 Query: 679 RVNCV 693 V V Sbjct: 187 GVTTV 191 >UniRef50_A3CU09 Cluster: Short-chain dehydrogenase/reductase SDR; n=5; cellular organisms|Rep: Short-chain dehydrogenase/reductase SDR - Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1) Length = 249 Score = 92.7 bits (220), Expect = 8e-18 Identities = 55/184 (29%), Positives = 88/184 (47%), Gaps = 1/184 (0%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 R KV ++T ST GIG A AK + +EG VV+ R E + V ++ G V + Sbjct: 3 RMENKVCVITGSTSGIGEACAKDMAAEGGKVVVSGRNEKEGARIVNEIKEAGGEVIFIRA 62 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 V + R L FG +D+ + + + WD++ DVN+K +L Sbjct: 63 DVTVEDDVRNLVAKTVEAFGRLDVFVANSGVGSLGDP-HEVETEEWDRVLDVNLKGIFLC 121 Query: 508 AKEAYPELVKRG-GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRV 684 K A +++K+G GG+IV SI ++ + + AYG +K + LT+ + + IR Sbjct: 122 DKYAVQQMLKQGQGGAIVNTGSIHSFVAKQGVTAYGAAKGGVAMLTRTLGTSYAAQGIRA 181 Query: 685 NCVA 696 N VA Sbjct: 182 NFVA 185 >UniRef50_Q8YNV5 Cluster: Alr4456 protein; n=14; Bacteria|Rep: Alr4456 protein - Anabaena sp. (strain PCC 7120) Length = 267 Score = 92.3 bits (219), Expect = 1e-17 Identities = 58/181 (32%), Positives = 94/181 (51%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 +G+ A++T +T+GIG AIA+ + GA VVI +R + + +++ S G V GV V Sbjct: 21 AGRKALITGATKGIGLAIAQEFLALGAEVVIVARNAEAIEQQMKAWHSAG-KVHGVAADV 79 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 + E R+ + + + FG +DIL D E+ + IF +N+ S + L++ Sbjct: 80 STSEGRQMMLDYVSKTFGELDILVNNVGTNIRKKAT-DYTEEEFAAIFQINLTSIFELSR 138 Query: 514 EAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 YP L SIV I S+A YG++K L+ LT+++A E + IRVN + Sbjct: 139 LFYPLLKTSKNSSIVNIGSVAGLISVRTGAPYGMTKAALVQLTRSLAVEWADDGIRVNAI 198 Query: 694 A 696 A Sbjct: 199 A 199 >UniRef50_Q826D4 Cluster: Putative 3-oxoacyl-ACP reductase; n=1; Streptomyces avermitilis|Rep: Putative 3-oxoacyl-ACP reductase - Streptomyces avermitilis Length = 268 Score = 92.3 bits (219), Expect = 1e-17 Identities = 56/180 (31%), Positives = 93/180 (51%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVA 336 G+VA+VT ++ GIG A+A+ + GA V + +R V +A + L G+ VA Sbjct: 9 GRVAVVTGASRGIGRAVAEAFAAAGAHVCVTARDADGVRRAAEELGGVGLAGS-----VA 63 Query: 337 NHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKE 516 + H R L E+A + FG +D++ ++D D W + F +NV++ L + Sbjct: 64 DPAHPRELTELALAAFGRLDVVVNNAATNEPYGPLMDADPDRWREAFTINVEAPLRLVQC 123 Query: 517 AYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVA 696 A+ + GG++V I + A +GAYG +K LL LT+ +A E + +RVN V+ Sbjct: 124 AWRAWMGEHGGAVVNICTEGAGHVGPNVGAYGTTKAALLHLTRQLAGE-LAPKVRVNSVS 182 >UniRef50_Q7D6M3 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family; n=8; Actinomycetales|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family - Mycobacterium tuberculosis Length = 260 Score = 92.3 bits (219), Expect = 1e-17 Identities = 54/184 (29%), Positives = 92/184 (50%) Frame = +1 Query: 142 STRFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGV 321 S +G+ AI+T ++ GIG AIA++L + GA VV+ +R++ +A + + GV Sbjct: 3 SLDLTGRTAIITGASRGIGLAIAQQLAAAGAHVVLTARRQEAADEAAAQVGDRAL---GV 59 Query: 322 VCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSW 501 H + + RR ++ +FG VDIL +L+ D + KIFDVN+ + Sbjct: 60 GAHAVDEDAARRCVDLTLERFGSVDILINNAGTNPAYGPLLEQDHARFAKIFDVNLWAPL 119 Query: 502 LLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIR 681 + + GG++V +SI + +G Y +K L+ +TK +A E + IR Sbjct: 120 MWTSLVVTAWMGEHGGAVVNTASIGGMHQSPAMGMYNATKAALIHVTKQLALE-LSPRIR 178 Query: 682 VNCV 693 VN + Sbjct: 179 VNAI 182 >UniRef50_Q7D960 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family; n=11; Mycobacterium|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family - Mycobacterium tuberculosis Length = 278 Score = 92.3 bits (219), Expect = 1e-17 Identities = 56/180 (31%), Positives = 87/180 (48%), Gaps = 1/180 (0%) Frame = +1 Query: 151 FSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCH 330 F G+ A++T GIG A GA VV+ + + +AV LR+EG V V+C Sbjct: 7 FPGRGAVITGGASGIGLATGTEFARRGARVVLGDVDKPGLRQAVNHLRAEGFDVHSVMCD 66 Query: 331 VANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLA 510 V + E L + A G VD++ I++ W + DV++ S Sbjct: 67 VRHREEVTHLADEAFRLLGHVDVV-FSNAGIVVGGPIVEMTHDDWRWVIDVDLWGSIHTV 125 Query: 511 KEAYPELVKRG-GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 + P L+++G GG +VF +S A P LGAYGV+K ++GL + +A E + I V+ Sbjct: 126 EAFLPRLLEQGTGGHVVFTASFAGLVPNAGLGAYGVAKYGVVGLAETLAREVTADGIGVS 185 >UniRef50_Q24N77 Cluster: Putative uncharacterized protein; n=1; Desulfitobacterium hafniense Y51|Rep: Putative uncharacterized protein - Desulfitobacterium hafniense (strain Y51) Length = 262 Score = 92.3 bits (219), Expect = 1e-17 Identities = 56/182 (30%), Positives = 88/182 (48%), Gaps = 2/182 (1%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRS-EGITVEGVVCH 330 +GKVAIVT T+GIGYA+A G + I SR ++ + + + + G+ G+ Sbjct: 13 TGKVAIVTGGTKGIGYAVAATFAMYGCDLAITSRTPADCERIAKDIETLYGVKCLGISAD 72 Query: 331 VANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLA 510 +N + R+ FG +DIL +LD E + + + N+K + A Sbjct: 73 SSNKDDIDRVVAQTVETFGKIDILINNAGISGKTAALLDQTEDDFMNVINTNLKGVFQFA 132 Query: 511 KEAYPELVKRG-GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 + ++ K+G GG IV I+S+ + + YG SK +L LTK +ANE I VN Sbjct: 133 QAVAAQIAKQGKGGRIVNIASVGGLIGGKSVAPYGASKAGVLSLTKTMANEWARYGITVN 192 Query: 688 CV 693 V Sbjct: 193 AV 194 >UniRef50_Q1YP85 Cluster: Short chain dehydrogenase; n=1; gamma proteobacterium HTCC2207|Rep: Short chain dehydrogenase - gamma proteobacterium HTCC2207 Length = 249 Score = 92.3 bits (219), Expect = 1e-17 Identities = 49/181 (27%), Positives = 88/181 (48%) Frame = +1 Query: 151 FSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCH 330 F +V ++T + G+GYA A+ G+ GA +VI + + KAV+ L G V G++ Sbjct: 5 FHDQVVLITGAAGGLGYACAQAFGAAGAKLVITDISKEPLDKAVEELEQAGAEVLGLIND 64 Query: 331 VANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLA 510 V++ + ++FG +DI + E +D++ VN+K WL Sbjct: 65 VSDSADVSAMMSAIVARFGRLDIAVNNAGTATPLQEFHEVGEAEFDRVMAVNLKGVWLCM 124 Query: 511 KEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNC 690 + +++++GGG IV ++S + Y SK + GLT+ +A E +IR+N Sbjct: 125 QAEIRQMLEQGGGRIVNMASATSRNTYPNASPYVTSKFAVAGLTRTVAVEYADRDIRINA 184 Query: 691 V 693 + Sbjct: 185 I 185 >UniRef50_Q1IIJ1 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Acidobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Acidobacteria bacterium (strain Ellin345) Length = 257 Score = 92.3 bits (219), Expect = 1e-17 Identities = 57/181 (31%), Positives = 85/181 (46%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 SGKVA+V T GIG AI+ L GA VV +R+E V A + G V V Sbjct: 8 SGKVAVVVGGTTGIGRAISFGLADAGADVVSTARREEQVNAAADEIERRGRQTLRVCSDV 67 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 + + L +KF VDIL L E W+KI D N+ + + Sbjct: 68 TSRASIQSLCNAVLAKFQKVDILVNCAGTTKRTPT-LTVSEDEWNKILDTNLTGALRACQ 126 Query: 514 EAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 +++RG G I+ I+S++++ + AY SK LL LT+++A E + + VN + Sbjct: 127 VFGKHMIERGYGRIINIASLSSFVALHEVAAYSASKAALLSLTRSLAVEWSKKGVTVNAI 186 Query: 694 A 696 A Sbjct: 187 A 187 >UniRef50_Q0SBS0 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=9; Bacteria|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Rhodococcus sp. (strain RHA1) Length = 249 Score = 92.3 bits (219), Expect = 1e-17 Identities = 53/180 (29%), Positives = 89/180 (49%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVA 336 G+ AIVT + GIG AIA +EGA +++ R E + AV GVV V Sbjct: 6 GRTAIVTGAASGIGAAIADAYAAEGAHLLLADRDEERLAAAVSRYSEGEAKAVGVVVDVT 65 Query: 337 NHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKE 516 + + + + + ++FG +DIL + + D WD++ V+++S +L + Sbjct: 66 DPDQTKMMVDRCLAEFGALDILVNCAGLLTEVP-LAEMDVATWDEMISVDLRSVFLCCRW 124 Query: 517 AYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVA 696 A P ++ +G G I+ ISS + L Y +K ++GLT+A+A E + VN +A Sbjct: 125 AVPHMLAQGSGRIINISSQLGIKGGVGLVHYCAAKAGVIGLTRALARELAPSGVLVNAIA 184 >UniRef50_Q094I4 Cluster: NAD-dependent epimerase/dehydratase; n=1; Stigmatella aurantiaca DW4/3-1|Rep: NAD-dependent epimerase/dehydratase - Stigmatella aurantiaca DW4/3-1 Length = 263 Score = 92.3 bits (219), Expect = 1e-17 Identities = 54/179 (30%), Positives = 92/179 (51%) Frame = +1 Query: 160 KVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVAN 339 KVA+VT ++ GIG+A A L +EGA VV C+R+E + + ++++G V V + Sbjct: 7 KVALVTGASSGIGWATALTLAAEGAKVVACARREDKGRELIALIQAQGGQATWVTADVLS 66 Query: 340 HEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKEA 519 + + A + +G +D I T+++ +D + NV+S++ K Sbjct: 67 ERDVEAMVQAALTTYGRLDGAFNNAGTSLSKPFIEMTNDE-YDTVMATNVRSAFWCMKYQ 125 Query: 520 YPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVA 696 ++ GGG+IV +S++A + L AY SK L LT+ +A E +NIR N V+ Sbjct: 126 LKAMLAGGGGAIVNCASVSAVRAMPGLSAYSASKAGLAALTRGVAVEYAQKNIRANTVS 184 >UniRef50_A5FRC2 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Dehalococcoides|Rep: Short-chain dehydrogenase/reductase SDR - Dehalococcoides sp. BAV1 Length = 265 Score = 92.3 bits (219), Expect = 1e-17 Identities = 58/181 (32%), Positives = 87/181 (48%), Gaps = 1/181 (0%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVA 336 GKVAIVT GIG I+ RL GAS++I K V +++ G + V+ Sbjct: 12 GKVAIVTGGAMGIGKGISMRLAEAGASIMIPDLNLEVAQKTVAEIKALGGKATAIQADVS 71 Query: 337 NHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKE 516 N +++ + FG +DI+ I D E +WDK +N+K ++ Sbjct: 72 NINDTQKVIDATLKAFGDLDIMVNNAGIYRFMPAI-DMTEAMWDKTLGINLKGLMFFSQA 130 Query: 517 AYPELV-KRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 A ++ + GG I+ I+SI ++PT L Y SK ++ LTKA+A E I VN V Sbjct: 131 AAKAMMAAKHGGKIINIASIDGFRPTGNLAHYDASKGGVIMLTKAMAQEWAPHGILVNAV 190 Query: 694 A 696 A Sbjct: 191 A 191 >UniRef50_A3HW24 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family protein; n=1; Algoriphagus sp. PR1|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family protein - Algoriphagus sp. PR1 Length = 265 Score = 92.3 bits (219), Expect = 1e-17 Identities = 60/181 (33%), Positives = 98/181 (54%), Gaps = 1/181 (0%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 R +GKV IVT ST GIG AIAK++ SEGA V+I +E + V L ++ + + Sbjct: 2 RLTGKVIIVTGSTTGIGKAIAKKVVSEGAKVIIHGLEEDLGQQVVSELGADNAKLH--IE 59 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 ++N +RL ++A +G +D + + DTD+ ++I +VN S +LL Sbjct: 60 DISNEGAAQRLVDIAVKTWGKLDSI-VNNAAIVAASTLFDTDKAFLNRILEVNTISPFLL 118 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHEN-IRV 684 + A +L+ + G+++ I SI AY L AY +SK L+ +T+ + + EN +RV Sbjct: 119 TQAAISQLI-QNKGAVLNIGSINAYSGEHNLLAYSISKGALMTMTRNLGDSLFRENGVRV 177 Query: 685 N 687 N Sbjct: 178 N 178 >UniRef50_Q97CM7 Cluster: Glucose 1-dehydrogenase; n=6; Archaea|Rep: Glucose 1-dehydrogenase - Thermoplasma volcanium Length = 261 Score = 92.3 bits (219), Expect = 1e-17 Identities = 64/181 (35%), Positives = 89/181 (49%) Frame = +1 Query: 151 FSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCH 330 F+ KVAIVT + GIG A+ L GA VV S E +S+ + Sbjct: 4 FTDKVAIVTGGSSGIGLAVVDALVRYGAKVVSVSLDE----------KSDVNVSDHFKID 53 Query: 331 VANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLA 510 V N E + E T K+G +DIL L T ++W +I DVNV S+L+A Sbjct: 54 VTNEEEVKEAVEKTTKKYGRIDILVNNAGIEQYSPLHL-TPTEIWRRIIDVNVNGSYLMA 112 Query: 511 KEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNC 690 K P ++ G GSI+ I+S+ +Y T+ AY SK LLGLT+++A + IR N Sbjct: 113 KYTIPVMLAIGHGSIINIASVQSYAATKNAAAYVTSKHALLGLTRSVAIDYA-PKIRCNA 171 Query: 691 V 693 V Sbjct: 172 V 172 >UniRef50_Q9K636 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=17; Bacteria|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Bacillus halodurans Length = 246 Score = 91.9 bits (218), Expect = 1e-17 Identities = 56/183 (30%), Positives = 86/183 (46%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 R +GKVA++T + GIG A AK+ EGA V++C +E V K V ++ G G V Sbjct: 2 RLNGKVAMITGAGRGIGAATAKKFAREGAKVIVCDVREEEVAKTVAEIQDGGGEALGSVV 61 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 V + + + +F +D++ TD Q WD + DVN+K +++ Sbjct: 62 DVTQRKDVKNVINQVIERFETLDVVVNNAGITADAQLTNMTDAQ-WDDVIDVNLKGVFIV 120 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 +E + ++ G I+ SS+ Y SK + G+TK A E NIRVN Sbjct: 121 TQEVTTIMKEQKRGVILNASSVVGSYGNFGQTNYAASKWGVNGMTKTWAKELGRYNIRVN 180 Query: 688 CVA 696 VA Sbjct: 181 AVA 183 >UniRef50_Q67M07 Cluster: Short-chain dehydrogenase; n=2; Bacteria|Rep: Short-chain dehydrogenase - Symbiobacterium thermophilum Length = 254 Score = 91.9 bits (218), Expect = 1e-17 Identities = 60/182 (32%), Positives = 90/182 (49%), Gaps = 2/182 (1%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKA-VQSLRSEGITVEGVVCHV 333 GKVAI+T + G+G A A+ EGA VVI E +G+A + ++ G V V Sbjct: 6 GKVAIITGAAMGMGAATAELFAREGARVVIADLNEE-LGRAQARKIQDAGGAAAFVRADV 64 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 + + + A FG +D+ + D DE VWD + V++K L K Sbjct: 65 SRAGDVEAMVQFAVDTFGRLDVAVNNAAHSPDTRPLADLDEAVWDAVIGVDLKGVALCLK 124 Query: 514 EAYPELVKR-GGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNC 690 +++K+ GGGSI+ ISS++ +P AY +K ++GLTK A + IRVN Sbjct: 125 YELRQMLKQGGGGSIINISSVSGIRPQPGTPAYVAAKHGVIGLTKQAAMDYSPHGIRVNA 184 Query: 691 VA 696 VA Sbjct: 185 VA 186 >UniRef50_Q62GY7 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family; n=36; Proteobacteria|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family - Burkholderia mallei (Pseudomonas mallei) Length = 269 Score = 91.9 bits (218), Expect = 1e-17 Identities = 63/193 (32%), Positives = 93/193 (48%), Gaps = 2/193 (1%) Frame = +1 Query: 124 PVRAIQSTRFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSE- 300 P R+ R +GKVAIVT + GIG AIA+ EGA+V I + ++ ++ + Sbjct: 5 PPRSGTVNRLAGKVAIVTGAGRGIGAAIARAFVREGAAVAIAELDAALAEESADAIARDT 64 Query: 301 -GITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIF 477 G V V VA E FG +D+L + TDE W + F Sbjct: 65 AGARVLAVPTDVARAESVAAALARTERAFGPLDVLVNNAGVNVFGDPLALTDED-WRRCF 123 Query: 478 DVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIAN 657 +++ W + A P +V+RG GSIV I+S A++ Y V+K +LGLT+A+ Sbjct: 124 AIDLDGVWNGCRAALPGMVERGRGSIVNIASTHAFKIIPGCFPYPVAKHGVLGLTRALGI 183 Query: 658 ETVHENIRVNCVA 696 E N+RVN +A Sbjct: 184 EYAPRNVRVNAIA 196 >UniRef50_Q0SJQ9 Cluster: Probable carveol dehydrogenase; n=1; Rhodococcus sp. RHA1|Rep: Probable carveol dehydrogenase - Rhodococcus sp. (strain RHA1) Length = 273 Score = 91.9 bits (218), Expect = 1e-17 Identities = 55/192 (28%), Positives = 88/192 (45%), Gaps = 13/192 (6%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVICS------------RKESNVGKAVQSLRSE 300 GKVA++T G G + A L + GA +V+C ++ + +Q ++ Sbjct: 9 GKVAVITGGARGQGRSHALTLAAAGAKIVVCDIAAPIGEVQYALATSDDIEETIQLVKEA 68 Query: 301 GITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFD 480 G + G+ V + R + ++A S+FG +DIL ++ ++ W + D Sbjct: 69 GGEIAGIQADVRSSADMRAVADLAVSQFGRIDILLANAGIHDHAESTIEIEDDAWQTMLD 128 Query: 481 VNVKSSWLLAKEAYPELVKRG-GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIAN 657 V V +W K P +++ G GGSIV SS+ + G YG +K L GL +A Sbjct: 129 VKVTGAWKACKAVVPVMIEGGRGGSIVITSSVDGLGASPSWGHYGAAKHGLQGLKDTLAF 188 Query: 658 ETVHENIRVNCV 693 E NIRVN V Sbjct: 189 ELADHNIRVNTV 200 >UniRef50_Q0RCN5 Cluster: Putative dehydrogenase/reductase; n=2; Frankia|Rep: Putative dehydrogenase/reductase - Frankia alni (strain ACN14a) Length = 295 Score = 91.9 bits (218), Expect = 1e-17 Identities = 55/181 (30%), Positives = 89/181 (49%), Gaps = 1/181 (0%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 +G++A++T T+GIG +A+ + GA V + R ++ + V+SL G + G+ V Sbjct: 50 AGRIALITGGTQGIGLGVAEAFLAAGARVAVVGRDKAKMDAVVESLAPLGEII-GIQADV 108 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 R+ FGG+DIL +LD E +D FD+NVK ++ A+ Sbjct: 109 TVVAEAARIVSATVDHFGGLDILATVAGVFEGAP-LLDATEADYDIQFDLNVKGTYFCAQ 167 Query: 514 EAYPELVKRGG-GSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNC 690 A LV +G G I+ + S+A + + YG +K + LT+ +A E I VNC Sbjct: 168 AAARHLVDQGRRGKIITVGSVAGLRAFPGVSVYGATKAAVGFLTQVLAGELAPHGINVNC 227 Query: 691 V 693 V Sbjct: 228 V 228 >UniRef50_A6EED4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Pedobacter sp. BAL39|Rep: Short-chain dehydrogenase/reductase SDR - Pedobacter sp. BAL39 Length = 250 Score = 91.9 bits (218), Expect = 1e-17 Identities = 54/183 (29%), Positives = 88/183 (48%) Frame = +1 Query: 145 TRFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVV 324 ++ KVA++T GIG+ IA+ + GAS I R + + +A L I + G Sbjct: 2 SKLKNKVAVITGGNSGIGFGIAEAFKNAGASGAIVGRNQETLKRAASQLGDGFIAING-- 59 Query: 325 CHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWL 504 V N R+ + +FG +DIL + D E +DK D+N+KS + Sbjct: 60 -DVTNPGDLERMMRNTSEQFGKIDIL-VANAGAGTTGTVADISESDYDKTMDLNLKSVYF 117 Query: 505 LAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRV 684 ++A P + G SI+ I S AA++ G YG +K ++ L K+ +N+ + IRV Sbjct: 118 TVQKALPYMA--DGSSIILIGSNAAHRAYPSFGLYGAAKAAVIFLAKSFSNDLLDRKIRV 175 Query: 685 NCV 693 N + Sbjct: 176 NVI 178 >UniRef50_A5VAV2 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Sphingomonas wittichii RW1|Rep: Short-chain dehydrogenase/reductase SDR precursor - Sphingomonas wittichii RW1 Length = 253 Score = 91.9 bits (218), Expect = 1e-17 Identities = 60/183 (32%), Positives = 87/183 (47%), Gaps = 4/183 (2%) Frame = +1 Query: 160 KVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVAN 339 K AIVT S GIG+ +A L GA V++C + AV LR EG+ +G+V VA+ Sbjct: 7 KAAIVTGSASGIGFDLAADLARRGAKVMLCDVADPMA--AVARLRDEGLDADGMVADVAD 64 Query: 340 HEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXI----LDTDEQVWDKIFDVNVKSSWLL 507 + +FG +DIL LD DE W ++ DVNV +L Sbjct: 65 PSAFAGVVAGCVDRFGRLDILVNNAGLFTTIGRAPFEELDVDE--WRRVLDVNVTGPFLC 122 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 ++ A P+L GGG I+ I S + + Y SK L +T+++A E + I VN Sbjct: 123 SRAALPQLRAAGGGRIINIGSATVFSAPPNMLHYVASKGALTAMTRSMAREVGKDGITVN 182 Query: 688 CVA 696 +A Sbjct: 183 LIA 185 >UniRef50_A3I6G4 Cluster: Putative 7-alpha-hydroxysteroid dehydrogenase; n=1; Bacillus sp. B14905|Rep: Putative 7-alpha-hydroxysteroid dehydrogenase - Bacillus sp. B14905 Length = 267 Score = 91.9 bits (218), Expect = 1e-17 Identities = 56/185 (30%), Positives = 86/185 (46%), Gaps = 2/185 (1%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 R KVA+VT GIG + A L EGA VVI +A SL EG + Sbjct: 3 RVQNKVALVTGGASGIGLSAATLLAKEGAKVVIADFNIEGAQEAAHSLVKEGYEASAIFL 62 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXX--ILDTDEQVWDKIFDVNVKSSW 501 + ++G + +L +++ D WD++ +VN+KS Sbjct: 63 DAGDASSIEAAVNFTVEQYGTLTVLFNNVGLTNLQKDLDVVNIDLDEWDRLVNVNLKSIL 122 Query: 502 LLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIR 681 L ++ A P + K GGGSI+ +S+AA+ + AYG +K ++ +TK IA + + IR Sbjct: 123 LGSRFAIPHMQKAGGGSIINTASMAAFASDQIRTAYGATKAGVVNMTKNIATQYGKDKIR 182 Query: 682 VNCVA 696 N VA Sbjct: 183 CNAVA 187 >UniRef50_A1ATN3 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Pelobacter|Rep: Short-chain dehydrogenase/reductase SDR - Pelobacter propionicus (strain DSM 2379) Length = 283 Score = 91.9 bits (218), Expect = 1e-17 Identities = 59/190 (31%), Positives = 94/190 (49%), Gaps = 7/190 (3%) Frame = +1 Query: 139 QSTRFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEG 318 ++ + GKVAI+T + GIG AIA RLG++GA++V+ N K + +++ G Sbjct: 17 ENMKLDGKVAIITGAGRGIGRAIALRLGADGAAMVVSDVNGDNATKVAEEIKARGGKAMA 76 Query: 319 VVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSS 498 + V + + L + A + G +DI+ I T + WD+I VN K + Sbjct: 77 LRTDVTSEADVKDLIDTAVRQHGRLDIMVANAGIANIKMSIEMTGAE-WDQIMAVNTKGA 135 Query: 499 WLLAKEAYPELVKRG-------GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIAN 657 +L A +++K+G GG I+ +SIAA+ L AY SK + G T+A+A Sbjct: 136 FLCDTMAARQMIKQGHSETPGSGGKIINCASIAAHSGFSILAAYSASKFAVRGFTQALAK 195 Query: 658 ETVHENIRVN 687 E I VN Sbjct: 196 ELGPYKINVN 205 >UniRef50_A0TVU3 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Burkholderia cenocepacia MC0-3|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia cenocepacia MC0-3 Length = 261 Score = 91.9 bits (218), Expect = 1e-17 Identities = 60/180 (33%), Positives = 86/180 (47%), Gaps = 2/180 (1%) Frame = +1 Query: 160 KVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVAN 339 KVA+VT + GIG A L S GA+VV E + V+ + V + N Sbjct: 14 KVAVVTGAGSGIGRETALLLASAGAAVVAADLNEEAAQETVKQIELSSGKAIAVKVDIGN 73 Query: 340 HEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKEA 519 ++E +K G +D+L + +T + WDK+ VN++ ++L +EA Sbjct: 74 ESSILAMYETVQAKLGRLDVLVNNAGIYPKTHFV-ETSAEKWDKVLGVNLRGTFLCMREA 132 Query: 520 YPELVKRG-GGSIVFISSIAAYQPT-EPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 + G GGSIV ISS+A+ QP G YG SK + LTK A E + IRVN V Sbjct: 133 IKRMQATGNGGSIVNISSVASQQPVIFDNGDYGASKAGVNNLTKVAALEFAGDRIRVNAV 192 >UniRef50_Q9F5J1 Cluster: SimJ1; n=5; Actinomycetales|Rep: SimJ1 - Streptomyces antibioticus Length = 273 Score = 91.5 bits (217), Expect = 2e-17 Identities = 56/178 (31%), Positives = 89/178 (50%) Frame = +1 Query: 163 VAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVANH 342 VAIVT + GIG A A+RL +EGA+V + R E++ V S+R+ G G+ C V Sbjct: 29 VAIVTGAGRGIGAATAQRLAAEGATVAVVDRTEADTADTVASIRAAGGRALGIGCDVTVT 88 Query: 343 EHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKEAY 522 + + ++FG +D+L + DE WD + DV++ + + A Sbjct: 89 DLVEAAVDRTVAEFGRLDVLVNNAGVTRDSLVFMMGDED-WDTVIDVHLNGAARTVRAAR 147 Query: 523 PELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVA 696 ++V++G G IV +SSIAA + Y +K + G T+ +A E I VN +A Sbjct: 148 RQMVRQGSGRIVNLSSIAAL-GNQGQANYATAKAAIQGYTRTLAVELGPHGITVNAIA 204 >UniRef50_Q0LZD3 Cluster: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR:Male sterility-like precursor; n=1; Caulobacter sp. K31|Rep: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR:Male sterility-like precursor - Caulobacter sp. K31 Length = 275 Score = 91.5 bits (217), Expect = 2e-17 Identities = 57/183 (31%), Positives = 86/183 (46%), Gaps = 3/183 (1%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVA 336 GKVA+VT + IG A L +GA VV+ + + L++EG V + Sbjct: 6 GKVALVTGAAGSIGSETALALAEQGARVVLTDLRAPELSAVTDRLKAEGHDVACKAGDIT 65 Query: 337 NHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDE---QVWDKIFDVNVKSSWLL 507 + + R + + A FGGVDIL LD + ++WD++ +N + L Sbjct: 66 SEDDIRAVVDFAAETFGGVDILDNNAGATGFSSRDLDIPDMPVELWDQVQSINARGPMLF 125 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 K A P ++ RGGGSIV ISS + AY SK + LT+ +A + +RVN Sbjct: 126 CKYAIPSMLARGGGSIVNISSGQSLSGDVSNFAYASSKAAVNALTRHLATAYSPKGVRVN 185 Query: 688 CVA 696 +A Sbjct: 186 AIA 188 >UniRef50_A5VEF9 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Sphingomonas wittichii RW1|Rep: Short-chain dehydrogenase/reductase SDR - Sphingomonas wittichii RW1 Length = 250 Score = 91.5 bits (217), Expect = 2e-17 Identities = 61/184 (33%), Positives = 87/184 (47%) Frame = +1 Query: 145 TRFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVV 324 TRF KV ++T GIG +R + GA VV R+ G+ Q R G+ V V Sbjct: 2 TRFEDKVVVITGGLGGIGLEACERFAAGGARVVAVDRRRDAGGRIAQGFRERGLDVRCRV 61 Query: 325 CHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWL 504 V + L + S +G DIL I+ D WD++ VN KS++L Sbjct: 62 ADVTSAVQVATLGQHVRSAYGRADIL-VNNAGMLSFAPIVGADANEWDRVQKVNCKSAFL 120 Query: 505 LAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRV 684 + + P + G G+I+ ISS A +PT AY ++K LL LT+ A E + IRV Sbjct: 121 MIRTFAP--LMAGKGAIINISSSAGLKPTANTAAYSIAKAGLLMLTQIAAME-LGPGIRV 177 Query: 685 NCVA 696 N +A Sbjct: 178 NAIA 181 >UniRef50_A5UWJ6 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Roseiflexus|Rep: Short-chain dehydrogenase/reductase SDR - Roseiflexus sp. RS-1 Length = 253 Score = 91.5 bits (217), Expect = 2e-17 Identities = 53/178 (29%), Positives = 83/178 (46%) Frame = +1 Query: 160 KVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVAN 339 K A +T GIG AIA GA+V + R + + ++ G V+C VA+ Sbjct: 7 KTAFITGGGRGIGRAIALTFSGAGATVAVAGRNREALDEVCATIEQRGGRAIAVICDVAD 66 Query: 340 HEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKEA 519 A + G DIL + DTD+ +W++I VN+ ++ K Sbjct: 67 PMQVYAAVSQARAAVGPFDILVNNAGVTYSAK-LTDTDDALWERIIQVNLNGAYYCCKAI 125 Query: 520 YPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 P+++ RGGG I+ I+S+AA AY +K LLGLT+++A E +I N + Sbjct: 126 VPDMIARGGGRIINIASMAALVGMPFSAAYSAAKHGLLGLTRSLALELQRYHITANAI 183 >UniRef50_A5CY54 Cluster: Dehydrogenases with different specificities; n=1; Pelotomaculum thermopropionicum SI|Rep: Dehydrogenases with different specificities - Pelotomaculum thermopropionicum SI Length = 254 Score = 91.5 bits (217), Expect = 2e-17 Identities = 61/181 (33%), Positives = 85/181 (46%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 SGKVA+VT GIG AIA L GA V + SR + + Q + +G + V Sbjct: 9 SGKVALVTGGGRGIGRAIAVALAGCGARVAVASRTLKEIEETRQIIAEKGGECLAIPADV 68 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 E L E A S +DIL + D E+ WD++ D N+K ++ + Sbjct: 69 TRVEAIYELVEKAYSWHNRLDILVNCAGINIAKFAV-DVTEEDWDRVLDTNLKGTFFCCQ 127 Query: 514 EAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 A +++ GGG I+ ISS A+ AY SK + LTK +A E N+ VNCV Sbjct: 128 AAGKKMIAGGGGRIINISSQMAHVGYYKRAAYCSSKGGVAQLTKVLAVEWAPHNVNVNCV 187 Query: 694 A 696 A Sbjct: 188 A 188 >UniRef50_A3Q7E9 Cluster: Short-chain dehydrogenase/reductase SDR; n=8; Actinomycetales|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium sp. (strain JLS) Length = 256 Score = 91.5 bits (217), Expect = 2e-17 Identities = 56/187 (29%), Positives = 91/187 (48%), Gaps = 2/187 (1%) Frame = +1 Query: 142 STRFS--GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVE 315 S RFS G+VA++T GIG A A L GA VV+ R+E + + + G Sbjct: 2 SDRFSMEGRVAVITGGGTGIGRASALVLAEHGADVVLAGRREEPLKATAADVEALGRRAI 61 Query: 316 GVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKS 495 V V + + L + +FG +D+L + TDE+ W ++ ++N+ S Sbjct: 62 AVPTDVTKADQCQALVDATLGEFGRLDVLLNNAGGGETKSLMKWTDEE-WHEVLELNLSS 120 Query: 496 SWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHEN 675 +W L++ A ++ +G G+IV ISS A+ Y +K L LT ++A + Sbjct: 121 AWYLSRAAAKPMIAQGKGAIVNISSGASLLAMPQAPVYAAAKAGLNNLTGSMAAAWTRKG 180 Query: 676 IRVNCVA 696 +RVNC+A Sbjct: 181 VRVNCIA 187 >UniRef50_A3PW05 Cluster: Short-chain dehydrogenase/reductase SDR; n=7; Corynebacterineae|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium sp. (strain JLS) Length = 256 Score = 91.5 bits (217), Expect = 2e-17 Identities = 53/181 (29%), Positives = 83/181 (45%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 +G+ A+VT T GIG A+A+ GA VV+ SRK +A + LR G GV H+ Sbjct: 13 TGRTAVVTGGTRGIGLALAEGFALAGARVVVASRKPDAYERAAEHLRGLGAQAVGVPTHL 72 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 + + L +FGG+DIL + + + W K +DVN++ L + Sbjct: 73 GDIDSLESLVNRTVEEFGGIDIL-VNNAANALAQPLGEMTPEAWTKSYDVNLRGPVFLVQ 131 Query: 514 EAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 A P L +++ S+ A+ + Y K LL T+++A IRVN + Sbjct: 132 HALPHLKASAHAAVLNTVSVGAFNFAPNVSMYAAGKAALLSFTRSMAAAYAPYGIRVNAL 191 Query: 694 A 696 A Sbjct: 192 A 192 >UniRef50_A0Z5Q6 Cluster: Short chain dehydrogenase; n=1; marine gamma proteobacterium HTCC2080|Rep: Short chain dehydrogenase - marine gamma proteobacterium HTCC2080 Length = 251 Score = 91.5 bits (217), Expect = 2e-17 Identities = 52/183 (28%), Positives = 86/183 (46%) Frame = +1 Query: 145 TRFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVV 324 + GKVA+VT GIG A A RL G +V + + +A L S+G +V Sbjct: 3 SELKGKVAVVTGGGAGIGLACAARLAEAGVAVGVADIDSAAAHQAAADLTSQGHRCVAIV 62 Query: 325 CHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWL 504 V+ + +LF++ FG ++I + DT+E+ +D++ VN+K WL Sbjct: 63 TDVSKAKEVEKLFQITNEAFGPINIAVNNAGVGAPLTPLGDTEEEDFDRVMAVNLKGVWL 122 Query: 505 LAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRV 684 + A + + GSI+ ++S + G Y SK + GLT++ A E IR+ Sbjct: 123 CMRAALRHMAPQKSGSIINMASALSTTTFPGSGLYTASKHGVAGLTRSAAVEYGESGIRI 182 Query: 685 NCV 693 N + Sbjct: 183 NAI 185 >UniRef50_Q8TUG0 Cluster: Gluconate 5-dehydrogenase; n=7; cellular organisms|Rep: Gluconate 5-dehydrogenase - Methanosarcina acetivorans Length = 255 Score = 91.5 bits (217), Expect = 2e-17 Identities = 54/182 (29%), Positives = 91/182 (50%), Gaps = 2/182 (1%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 +GKVAIVT ++ G+G A+ L ++GA++ I +R+E + + + + G+T +C V Sbjct: 8 TGKVAIVTGASSGLGVEFARALANQGANIAIIARREEKLKEVQKEIEKLGVTCRYYLCDV 67 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 E + E FG +DIL TDE +W + D N+ + A+ Sbjct: 68 MKTEQIKNAVEQVVKDFGRIDILVNNAGLGLVDAADKTTDE-MWHNMIDTNLNGVYFFAR 126 Query: 514 EAYPELVKRGGGSIVFISSIAAYQPTE--PLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 E ++++ G I+ I SI + + P+ AY +K +L LTK++A E E I VN Sbjct: 127 EVGKIMLRQKHGRIINIGSIHSTVSMKGLPVTAYCSTKGGVLMLTKSLATEWAKEGITVN 186 Query: 688 CV 693 + Sbjct: 187 AI 188 >UniRef50_O67610 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=9; Bacteria|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Aquifex aeolicus Length = 248 Score = 91.5 bits (217), Expect = 2e-17 Identities = 53/184 (28%), Positives = 92/184 (50%), Gaps = 1/184 (0%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSE-GITVEGVV 324 + GKV++VT ST GIG AIA++L S G++V+I + + ++ G+ GV Sbjct: 4 KLQGKVSLVTGSTRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEEIANKYGVKAHGVE 63 Query: 325 CHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWL 504 ++ + E + FE + G+DIL L W+++ VN+ ++L Sbjct: 64 MNLLSEESINKAFEEIYNLVDGIDILVNNAGITRDKL-FLRMSLLDWEEVLKVNLTGTFL 122 Query: 505 LAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRV 684 + + + +++K+ G IV ISS+ + Y +K L+G TK++A E N+ V Sbjct: 123 VTQNSLRKMIKQRWGRIVNISSVVGFTGNVGQVNYSTTKAGLIGFTKSLAKELAPRNVLV 182 Query: 685 NCVA 696 N VA Sbjct: 183 NAVA 186 >UniRef50_Q62AB7 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=14; Burkholderiales|Rep: 2-deoxy-D-gluconate 3-dehydrogenase - Burkholderia mallei (Pseudomonas mallei) Length = 256 Score = 91.1 bits (216), Expect = 2e-17 Identities = 60/182 (32%), Positives = 90/182 (49%), Gaps = 1/182 (0%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 +G+VA+VT GIG+A A+ L GASV + R G A +L G+ + Sbjct: 12 TGRVALVTGGAAGIGHACARLLAQRGASVALVDRHPETAGIAA-TLEGGAARHSGMSLDL 70 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 + + +A S+FGGVD+L LD E WD +NVK+S+ +A+ Sbjct: 71 RDCSAAQAGVALAASRFGGVDML-VNSAGVALLDKALDVGEAAWDATMAINVKASFFVAQ 129 Query: 514 EAYPELVKRG-GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNC 690 A +++ GG IV ++S A+ E AY SK ++G+TKA+A E I VN Sbjct: 130 AAARQMIAGARGGRIVNLASQASVVGLERHAAYCASKAAIVGMTKALALEWAPHGITVNA 189 Query: 691 VA 696 V+ Sbjct: 190 VS 191 >UniRef50_Q1IU03 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Acidobacteria bacterium Ellin345|Rep: Short-chain dehydrogenase/reductase SDR precursor - Acidobacteria bacterium (strain Ellin345) Length = 252 Score = 91.1 bits (216), Expect = 2e-17 Identities = 54/182 (29%), Positives = 83/182 (45%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 + GK AIVT + GIG A + SEGA ++ + + S G + Sbjct: 2 KLKGKTAIVTGAAAGIGKASTELFASEGAHILAIDLDGGKLEHLASKITSSGGICLALRG 61 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 V+ + A +FG +DIL + T+EQ WD+ +NVKS +L Sbjct: 62 DVSQSADVQNALNTAIGRFGKIDILFNNAGIVPAGKIDVTTEEQ-WDRAMAINVKSMYLF 120 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 P + GGG I+ +S A + Y +K ++GLTK++A + V +NIRVN Sbjct: 121 CHAIVPHFKEHGGGVILNTASATALRAVVDRACYTATKAAVVGLTKSMALDYVRDNIRVN 180 Query: 688 CV 693 C+ Sbjct: 181 CL 182 >UniRef50_Q12DF3 Cluster: Short-chain dehydrogenase/reductase SDR; n=38; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 250 Score = 91.1 bits (216), Expect = 2e-17 Identities = 49/178 (27%), Positives = 88/178 (49%) Frame = +1 Query: 160 KVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVAN 339 +VA++T +G+GYA A+R+ + GA+V + + +A ++L+ G + VV + + Sbjct: 9 RVAVITGGAQGMGYATAQRMLASGAAVALWDIDAQRLAQARETLKPSGKVITAVV-ELTD 67 Query: 340 HEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKEA 519 + + FG +DIL + +VW ++ +VN+ +L ++ Sbjct: 68 EASVEAATQATLAAFGRIDILVNNAGITGGNGTTWELAPEVWRRVIEVNLIGPYLTSRAI 127 Query: 520 YPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 P +VK+G G IV I+S+A + Y SK L+GLTK++ E + VN V Sbjct: 128 VPHMVKQGYGRIVNIASVAGKEGNPNASHYSASKAGLIGLTKSLGKELAKTGVLVNAV 185 >UniRef50_Q03906 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n=3; Clostridium|Rep: 7-alpha-hydroxysteroid dehydrogenase - Eubacterium sp. (strain VPI 12708) Length = 266 Score = 91.1 bits (216), Expect = 2e-17 Identities = 60/184 (32%), Positives = 86/184 (46%), Gaps = 2/184 (1%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 R KV +VTAST GIG AIA+ EGA V + +R + + G V+ V Sbjct: 2 RLKDKVILVTASTRGIGLAIAQACAKEGAKVYMGARNLERAKARADEMNAAGGNVKYVYN 61 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXX--ILDTDEQVWDKIFDVNVKSSW 501 E + E + G +D+L I +TD +V+ K ++N+KS + Sbjct: 62 DATKEETYVTMIEEIIEQEGRIDVLVNNFGSSNPKKDLGIANTDPEVFIKTVNINLKSVF 121 Query: 502 LLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIR 681 + ++ A + + GGGSI+ ISS+ P AYG SK + LTK IA NIR Sbjct: 122 IASQTAVKYMAENGGGSIINISSVGGLIPDISQIAYGTSKAAINYLTKLIAVHEARHNIR 181 Query: 682 VNCV 693 N V Sbjct: 182 CNAV 185 >UniRef50_A5UYE2 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Roseiflexus|Rep: Short-chain dehydrogenase/reductase SDR - Roseiflexus sp. RS-1 Length = 248 Score = 91.1 bits (216), Expect = 2e-17 Identities = 55/183 (30%), Positives = 88/183 (48%), Gaps = 1/183 (0%) Frame = +1 Query: 151 FSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCH 330 F+ V ++T GIG A A G GA VVI +R S + V ++R+ G T V Sbjct: 2 FNESVVVITGGGSGIGRATALAFGRHGARVVIGNRNASTGEETVAAIRATGGTALFVPTD 61 Query: 331 VANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLA 510 V R L + + FG +DI + D DE+ +D +FD NV+ ++L Sbjct: 62 VTQPVAVRALIDTTVATFGRLDIAFNNAGWFGPVAPLADQDEREFDPVFDTNVRGTFLCM 121 Query: 511 KEAYPELVKRGGGSIV-FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 K +++K+G G I+ S+ A T + Y +K ++ LT++ A E + +R+N Sbjct: 122 KYELAQMLKQGQGIIINNASTTGARNSTVGVALYAAAKAAVISLTRSAAMEYAAQGVRIN 181 Query: 688 CVA 696 VA Sbjct: 182 AVA 184 >UniRef50_A5P1L6 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=2; Alphaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR precursor - Methylobacterium sp. 4-46 Length = 275 Score = 91.1 bits (216), Expect = 2e-17 Identities = 57/183 (31%), Positives = 89/183 (48%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 R + KVA+VT GIG A+A+ EGA++VI + A L G V Sbjct: 4 RLADKVALVTGGARGIGLAVARAFAREGAALVIADVNRAGAEAAAAGLAEAGGRAMAVAV 63 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 VA+ + E ++ G +DIL L+T + W++I +N+ ++L+ Sbjct: 64 DVADPASIAAMVEAILARHGRLDILVNNAGVGGNTP-FLETRLEDWNRIIGINLTGAFLV 122 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 A+ E+V+ GGG IV I+S++ + + AYG +K L LTK +A E I VN Sbjct: 123 AQACAREMVRGGGGKIVNIASLSGQRGGDGRAAYGAAKAGLELLTKVMAVELSEHGINVN 182 Query: 688 CVA 696 +A Sbjct: 183 NIA 185 >UniRef50_A0YDP4 Cluster: Short chain dehydrogenase; n=1; marine gamma proteobacterium HTCC2143|Rep: Short chain dehydrogenase - marine gamma proteobacterium HTCC2143 Length = 264 Score = 91.1 bits (216), Expect = 2e-17 Identities = 59/184 (32%), Positives = 92/184 (50%), Gaps = 3/184 (1%) Frame = +1 Query: 151 FSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQS---LRSEGITVEGV 321 F K+ ++T + GIG A GA+V S++ ++V + L IT+EG Sbjct: 10 FDDKIVLITGAAGGIGLATTLAFVRSGATVFAMDLLGSSLAESVAAMTDLSGSIITIEG- 68 Query: 322 VCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSW 501 V + +R + T +FGG+DIL + DE V+D++ VN K ++ Sbjct: 69 --DVTQADDWQRAVDTITGEFGGLDILVNNAGIIEAGSRLEKFDENVFDRVMAVNTKGTF 126 Query: 502 LLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIR 681 L K P + KR GG+IV +SSI+ + + AY SK +LG+TK+ A + +IR Sbjct: 127 LGMKAVIPAMRKRHGGAIVNVSSISGHCGSAVATAYTASKHAVLGMTKSAALDLAEYDIR 186 Query: 682 VNCV 693 VN V Sbjct: 187 VNAV 190 >UniRef50_Q2U8E2 Cluster: Dehydrogenases with different specificities; n=4; Aspergillus|Rep: Dehydrogenases with different specificities - Aspergillus oryzae Length = 273 Score = 91.1 bits (216), Expect = 2e-17 Identities = 62/187 (33%), Positives = 94/187 (50%), Gaps = 8/187 (4%) Frame = +1 Query: 157 GKVAIVTASTE-------GIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVE 315 GKVA+VT + G G A A+ L GA + C + + + L +EG E Sbjct: 13 GKVALVTGIGQMGDPQMWGNGAATARVLSRNGAKIFGCDLQLESALHTKKRLEAEGGVCE 72 Query: 316 GVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKS 495 +V + E +R+ EV +KFG +DIL + E+VWD D+N+KS Sbjct: 73 VTTANVTSSEDVKRMVEVCVAKFGRIDILINNVGRSEPGGPA-EMTEKVWDAQTDINLKS 131 Query: 496 SWLLAKEAYPELVKRGGGSIVFISSIAAYQPT-EPLGAYGVSKTTLLGLTKAIANETVHE 672 +L E P + K+GGG+IV ++SIA + +P AY +K+ ++ TKA A + Sbjct: 132 VYLSCHEVLPIMEKQGGGAIVNVASIAGIRYIGKPQVAYSAAKSAVIQFTKATAVIYANR 191 Query: 673 NIRVNCV 693 NIR+N V Sbjct: 192 NIRLNVV 198 >UniRef50_P16544 Cluster: Putative ketoacyl reductase; n=42; Bacteria|Rep: Putative ketoacyl reductase - Streptomyces coelicolor Length = 261 Score = 91.1 bits (216), Expect = 2e-17 Identities = 55/180 (30%), Positives = 84/180 (46%), Gaps = 2/180 (1%) Frame = +1 Query: 160 KVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVAN 339 +VA+VT +T GIG IA+RLG EG V +C+R E + ++ LR G+ +G C V + Sbjct: 7 EVALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRTTLKELREAGVEADGRTCDVRS 66 Query: 340 HEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKEA 519 L ++G VD+L DE +W + + N+ + + K+ Sbjct: 67 VPEIEALVAAVVERYGPVDVLVNNAGRPGGGATAELADE-LWLDVVETNLTGVFRVTKQV 125 Query: 520 YPE--LVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 +++RG G IV I+S Q Y SK ++G TKA+ E I VN V Sbjct: 126 LKAGGMLERGTGRIVNIASTGGKQGVVHAAPYSASKHGVVGFTKALGLELARTGITVNAV 185 >UniRef50_Q3W9J0 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Frankia sp. EAN1pec|Rep: Short-chain dehydrogenase/reductase SDR - Frankia sp. EAN1pec Length = 259 Score = 90.6 bits (215), Expect = 3e-17 Identities = 58/182 (31%), Positives = 87/182 (47%), Gaps = 1/182 (0%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 +GK+A+VT IG A+ RL EGA VV+ E+ ++ I GV V Sbjct: 6 TGKIAVVTGGAGVIGAAVCDRLAREGAKVVVADLDEAAAKHVADTVGGGAI---GVAADV 62 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 + + +VA + FG +D+L + D D + K+F VNV ++L A+ Sbjct: 63 STPDGATACVDVAVAAFGRLDLLHANAGVECVVQPVADFDPGDYHKVFGVNVLGAFLSAQ 122 Query: 514 EAYPELVKR-GGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNC 690 A +L + GGG I+F +SIAA T Y SK + G+ + +A E IRVN Sbjct: 123 AAVRQLTAQGGGGQILFTASIAALMGTGGTSVYNASKHAVHGIARCLALEVAGTGIRVNT 182 Query: 691 VA 696 +A Sbjct: 183 LA 184 >UniRef50_Q0S4C7 Cluster: Reductase; n=4; Bacteria|Rep: Reductase - Rhodococcus sp. (strain RHA1) Length = 253 Score = 90.6 bits (215), Expect = 3e-17 Identities = 59/184 (32%), Positives = 86/184 (46%), Gaps = 1/184 (0%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 + GKVA++T + +GIG IA L EGA + + R ES + + L G E VVC Sbjct: 3 KLDGKVALITGAGQGIGQGIALALAREGAVIAVAGRTESKLHGTCERLTELGARSEPVVC 62 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 V+ E FGGVDIL + DE+ +++ F ++ + Sbjct: 63 DVSRRADIASAVERTVDVFGGVDILVNNANDCTPGPILSVIDEE-YERSFATGPLATLRM 121 Query: 508 AKEAYPELVKRGGGSIV-FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRV 684 + +P +V RGGG IV ++S A GAYG K + LT++ A E + IRV Sbjct: 122 MQSCHPHMVSRGGGVIVNLVTSAAVRWDASNYGAYGSIKEGMRSLTRSAACEWGRDGIRV 181 Query: 685 NCVA 696 VA Sbjct: 182 LSVA 185 >UniRef50_A6AFC6 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=1; Vibrio cholerae 623-39|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Vibrio cholerae 623-39 Length = 256 Score = 90.6 bits (215), Expect = 3e-17 Identities = 54/180 (30%), Positives = 91/180 (50%), Gaps = 1/180 (0%) Frame = +1 Query: 160 KVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVAN 339 K +VT ++ GIG I++ +GA V+I R + + + L G ++C++ N Sbjct: 13 KKVLVTGASSGIGRIISQVFSVQGARVIIVGRDSERLTQTLDIL--SGDEHHAIICNLTN 70 Query: 340 HEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKEA 519 E RLF+ A S G +D + + E +D++F NVKS+ +AK Sbjct: 71 PEDIERLFDEAFSLVGEIDAVVHCAGIQKTLP-LQAIKEIDFDEVFSTNVKSAQFIAKSY 129 Query: 520 YPEL-VKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVA 696 + + G S++F+SS+AA + Y SK LLGL++++A+E IRVNC++ Sbjct: 130 RKKSRYNKSGSSLIFLSSVAAACGEPAISTYSASKAALLGLSRSLASELARNKIRVNCIS 189 >UniRef50_A4FCN3 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Actinomycetales|Rep: Short-chain dehydrogenase/reductase SDR - Saccharopolyspora erythraea (strain NRRL 23338) Length = 267 Score = 90.6 bits (215), Expect = 3e-17 Identities = 57/182 (31%), Positives = 88/182 (48%), Gaps = 1/182 (0%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 +GKVA +T + GIG A A+ EGA V++ +R E+ + + +R+ G T VVC + Sbjct: 20 AGKVAFITGAGRGIGAAAARLFAREGARVLLAARTEAQLKTVAEEIRAAGGTANYVVCDL 79 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWL-LA 510 A+ R + A + +G +DI + E +D I+DVN+K WL + Sbjct: 80 ADATSVRAAVDRAVNLYGRLDIAFNNGATIQQPGPMDQMPEADFDHIYDVNLKGVWLAMV 139 Query: 511 KEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNC 690 E G G++V SS+ + L AYG K + LT++ A E IRVN Sbjct: 140 AEIAAIRTTAGTGAVVNNSSVGSLMGNPELPAYGAMKRAVNSLTESAAVTYGPEGIRVNA 199 Query: 691 VA 696 +A Sbjct: 200 IA 201 >UniRef50_Q5NPD9 Cluster: Dehydrogenase; n=1; Zymomonas mobilis|Rep: Dehydrogenase - Zymomonas mobilis Length = 261 Score = 90.2 bits (214), Expect = 4e-17 Identities = 55/182 (30%), Positives = 93/182 (51%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 + +GK A+VT ST GIG AIA+R EGA+V+IC R +S + A+++ + V+ V+ Sbjct: 4 QLTGKTALVTGSTSGIGLAIAQRFAEEGANVIICGRSQSKLEAALKTFPAPE-KVKAVLA 62 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 + + T + VDIL TD++ W IF+VNV S L Sbjct: 63 DAGSQAG----IDALTKEVPAVDILINNLGIFEPKAFSDITDDE-WHHIFEVNVMSGVRL 117 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 ++ +P+++++ G I+F+SS Y ++KT L +++ +A ET + VN Sbjct: 118 SRYYFPKMIEKNWGRIIFVSSECGVVTPGDTIHYAMTKTAQLAISRGLAEETKGTAVTVN 177 Query: 688 CV 693 + Sbjct: 178 TI 179 >UniRef50_Q1BBB6 Cluster: Short-chain dehydrogenase/reductase SDR; n=5; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium sp. (strain MCS) Length = 266 Score = 90.2 bits (214), Expect = 4e-17 Identities = 61/199 (30%), Positives = 93/199 (46%) Frame = +1 Query: 100 LNISTSANPVRAIQSTRFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKA 279 ++ T++N V + R GK A++T + GIG A A EGA +V+ + + Sbjct: 1 MSTETTSNAVTR-EHGRLHGKSAVITGAAFGIGRATAVLFAREGARLVVTDIQSEPLLAL 59 Query: 280 VQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQ 459 LR G VE VV V+ R+ A +FG +D+L L+ Sbjct: 60 ADELRHAGADVEPVVGDVSVEYDAGRMIGAAVDRFGRLDVLVANAGIIPLGDA-LEMTAA 118 Query: 460 VWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGL 639 WD++ ++ + +L K A ++ GGG+IV +SSI+ + AYG +K GL Sbjct: 119 GWDEVMAIDGRGMFLCCKFAIEAMLPTGGGAIVCLSSISGLAGQKRQAAYGPAKFIATGL 178 Query: 640 TKAIANETVHENIRVNCVA 696 TK +A E IRVN VA Sbjct: 179 TKHLAVEWADRGIRVNAVA 197 >UniRef50_Q182R6 Cluster: Probable short chain dehydrogenase precursor; n=2; Clostridium difficile|Rep: Probable short chain dehydrogenase precursor - Clostridium difficile (strain 630) Length = 245 Score = 90.2 bits (214), Expect = 4e-17 Identities = 51/180 (28%), Positives = 90/180 (50%), Gaps = 1/180 (0%) Frame = +1 Query: 160 KVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSE-GITVEGVVCHVA 336 K ++T GIG A++K EG +V++ K N K + ++ +E +V+ +++ Sbjct: 4 KTVLITGGARGIGKAMSKAFAKEGYNVLVNFNKSENEAKELYTILNEKNFSVKLFKANIS 63 Query: 337 NHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKE 516 N E + + +FGG+D+L TDE WD + ++N+K S+ ++ Sbjct: 64 NREDVEDMVDYCIKEFGGLDVLVNNAGVSQDKLFTDITDED-WDNMMNINLKGSFYCSQV 122 Query: 517 AYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVA 696 A ++ G+I+ ISSI Y ++K ++G+TKA+A E NIRVN +A Sbjct: 123 ALKYMISEKKGNIINISSIWGISGASCEVHYSITKAGIIGMTKALAKEVGPSNIRVNSIA 182 >UniRef50_A3JBQ4 Cluster: Short-chain dehydrogenase/reductase SDR; n=4; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Marinobacter sp. ELB17 Length = 264 Score = 90.2 bits (214), Expect = 4e-17 Identities = 61/185 (32%), Positives = 85/185 (45%), Gaps = 3/185 (1%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 RF G+ AIVT + GIG A A RL EGA V++ E + + +L EG + Sbjct: 3 RFDGRAAIVTGAGSGIGRATALRLACEGAQVIMADTSELGLAET-GNLMPEGAEYLRRLV 61 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXX---ILDTDEQVWDKIFDVNVKSS 498 VA+ + L A FG +DIL +++ + WDK+ VN+ + Sbjct: 62 DVADEAQVKELVSDAMDAFGKIDILCNIAGIASTGKGHPPVIENERDEWDKVLSVNLIGT 121 Query: 499 WLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENI 678 LL K P + R GSIV +SIA + AY SK ++ LT A + NI Sbjct: 122 MLLIKHVAPHMQARKLGSIVNTASIAGIRSGAGGNAYSASKAGVINLTMTAACDLGDHNI 181 Query: 679 RVNCV 693 RVN V Sbjct: 182 RVNAV 186 >UniRef50_A1WEP3 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Verminephrobacter eiseniae EF01-2|Rep: Short-chain dehydrogenase/reductase SDR precursor - Verminephrobacter eiseniae (strain EF01-2) Length = 254 Score = 90.2 bits (214), Expect = 4e-17 Identities = 56/182 (30%), Positives = 88/182 (48%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 RF+ KVA VT + G+G A A L +EGA +++ R E+ + + ++ ++ G Sbjct: 4 RFAHKVAAVTGAASGLGRATALALAAEGARILLFDRDEAGLAETARACPG-AVSAVGDAS 62 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 A+ R A + G V++L ++ EQ WD++F VNVK WL Sbjct: 63 SAADIA---RAEAQALRELGPVELLVPAAGMLGPAKPAIELQEQEWDRLFAVNVKGPWLA 119 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 A+ P + + G G+I SS A + L Y SK ++ L +++A E IRVN Sbjct: 120 ARAFVPHMRQIGHGAICMFSSTAGLAGSPFLSGYSASKGAVVLLARSLALNHAAEKIRVN 179 Query: 688 CV 693 CV Sbjct: 180 CV 181 >UniRef50_Q9LW35 Cluster: Alcohol dehydrogenase-like protein; n=6; rosids|Rep: Alcohol dehydrogenase-like protein - Arabidopsis thaliana (Mouse-ear cress) Length = 300 Score = 90.2 bits (214), Expect = 4e-17 Identities = 56/187 (29%), Positives = 89/187 (47%), Gaps = 2/187 (1%) Frame = +1 Query: 142 STRFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGV 321 S + GKVA++T GIG A A+ S+GA V+I E G V + G + Sbjct: 33 SRKLEGKVAVITGGASGIGKATAEEFVSQGAQVIIVDIDEE-AGHMVAT--ELGSAAHFL 89 Query: 322 VCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXX--ILDTDEQVWDKIFDVNVKS 495 C V E + E A ++ G +D++ I D D +DK+ +NV+ Sbjct: 90 RCDVTEEEQIAKAVETAVTRHGKLDVMLNSAGISCSISPPSIADLDMDTYDKVMRLNVRG 149 Query: 496 SWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHEN 675 + L K A ++ G GSI+ +SSI+ AY +SK T+ G+ K +A+E Sbjct: 150 TVLGIKHAARAMIPAGSGSILCLSSISGLMGGLGPHAYSISKFTIPGVVKTVASELCKHG 209 Query: 676 IRVNCVA 696 +R+NC++ Sbjct: 210 LRINCIS 216 >UniRef50_Q0DM18 Cluster: Os03g0833100 protein; n=5; Oryza sativa|Rep: Os03g0833100 protein - Oryza sativa subsp. japonica (Rice) Length = 274 Score = 90.2 bits (214), Expect = 4e-17 Identities = 61/188 (32%), Positives = 91/188 (48%), Gaps = 1/188 (0%) Frame = +1 Query: 136 IQSTRFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVE 315 + TR GKVAIVT GIG A A+ S GA+VVI ++ +G+AV + + G Sbjct: 10 MSKTRMDGKVAIVTGGASGIGEAAARLFASCGATVVIADVQDE-LGEAVAASVAGG-GCR 67 Query: 316 GVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKS 495 V C V + A ++ G +D++ ++D D D++ VN + Sbjct: 68 YVRCDVTDEAQVEAAVAAAVAEHGRLDVMVSNAGVLLPTGPVVDMDLAALDRVMSVNFRG 127 Query: 496 SWLLAKEAYPELVKRGG-GSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHE 672 + K A +V RG G+IV +S+A+ Q AY SK +LGL +A A E Sbjct: 128 AAACVKHAARAMVSRGTRGAIVCTASVASCQGGFGPAAYTASKHAVLGLVRAAAGELGRH 187 Query: 673 NIRVNCVA 696 +RVNCV+ Sbjct: 188 GVRVNCVS 195 >UniRef50_Q5V623 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=1; Haloarcula marismortui|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Haloarcula marismortui (Halobacterium marismortui) Length = 280 Score = 90.2 bits (214), Expect = 4e-17 Identities = 57/179 (31%), Positives = 89/179 (49%), Gaps = 2/179 (1%) Frame = +1 Query: 166 AIVTASTEGIGYAIAKRLGSEGASVVICSRKESNV-GKAVQSLRSEGITVEGVVCHVANH 342 AIVT ++ GIG IA R G VV+CSR +V A + ++ V V C V + Sbjct: 11 AIVTGASRGIGREIAARFAEAGGDVVVCSRTYEDVEAVATELTQTHDGRVVPVECDVTDR 70 Query: 343 EHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDT-DEQVWDKIFDVNVKSSWLLAKEA 519 E R L + +FG + +L +L DE+ ++ + D+N+KS +LL+KE Sbjct: 71 EAVRDLVDTTIQEFGDIRVLVNNAGGADESANLLHRCDEETFESMVDLNLKSQFLLSKEV 130 Query: 520 YPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVA 696 P +V GGGSI+ + S+ L Y +K+ LL L++ IA +R N ++ Sbjct: 131 LPAMVAAGGGSIIHMGSVNGLFGI-GLSGYSEAKSGLLALSRNIAAHYGQHGVRSNVIS 188 >UniRef50_A5UJ48 Cluster: Short chain dehydrogenase; n=1; Methanobrevibacter smithii ATCC 35061|Rep: Short chain dehydrogenase - Methanobrevibacter smithii (strain PS / ATCC 35061 / DSM 861) Length = 269 Score = 90.2 bits (214), Expect = 4e-17 Identities = 60/184 (32%), Positives = 87/184 (47%), Gaps = 2/184 (1%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 R K+AIVT ST GIG IAK +EGA VVIC R+E V ++ EG Sbjct: 5 RLKDKIAIVTGSTSGIGIGIAKLYAAEGAKVVICGRREEKGQAVVDNITKEGGESSYHFF 64 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILD-TDEQVWDKIFDVNVKSSWL 504 + N +L + K+G +DIL +D +WD IF+ +++ ++ Sbjct: 65 DITNTNSIEKLIDDTAEKYGKIDILVNNAANVALKDGNIDELTIDMWDAIFESDLRGTFY 124 Query: 505 LAKEAYPELVK-RGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIR 681 K P L K GGSI+ I S+A+ AY +K+ + T+ A + +NIR Sbjct: 125 ATKCVIPYLQKNENGGSIINIGSMASCGGDLGSTAYACAKSGVDMFTQYTALQYGKDNIR 184 Query: 682 VNCV 693 NCV Sbjct: 185 CNCV 188 >UniRef50_Q8ELN8 Cluster: Glucose 1-dehydrogenase; n=6; cellular organisms|Rep: Glucose 1-dehydrogenase - Oceanobacillus iheyensis Length = 256 Score = 89.8 bits (213), Expect = 6e-17 Identities = 56/180 (31%), Positives = 90/180 (50%), Gaps = 1/180 (0%) Frame = +1 Query: 160 KVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVAN 339 KVAIVT + G+G A A A VVI E + V+ ++ G + +++ Sbjct: 9 KVAIVTGAAMGMGKATAILFAESKAKVVIADFNEEKGQEVVEEVKQAGGQAAFIKVDISD 68 Query: 340 HEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKEA 519 +++ + A +FG +DI + DE WDK+ V++ + L K Sbjct: 69 SAQVKQMVQFAVDQFGKLDIAVNNAALTPDDKPASEFDEDYWDKLISVDLTGTALCMKYE 128 Query: 520 YPELVKRG-GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVA 696 +L+++G GGSIV ISS++ ++P AY +K ++G+TK A E +NIRVN VA Sbjct: 129 LQQLLEQGNGGSIVNISSVSGFRPQPNNIAYVAAKHGVVGMTKVAALENGPQNIRVNTVA 188 >UniRef50_Q7WAF7 Cluster: Putative oxidoreductase; n=3; Bordetella|Rep: Putative oxidoreductase - Bordetella parapertussis Length = 262 Score = 89.8 bits (213), Expect = 6e-17 Identities = 51/183 (27%), Positives = 92/183 (50%), Gaps = 1/183 (0%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 R +G+VA++T + GIG A A R +EGA++ + R+ + + + +G GV Sbjct: 13 RLAGRVALITGAAGGIGSAAALRFAAEGAALALLDRRPDAIEQLAGRICGQGGQAIGVAA 72 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILD-TDEQVWDKIFDVNVKSSWL 504 V + + R+ A FG +D L +D D +W++ +++ S+ L Sbjct: 73 DVTDDDSVRQAVRRAVEHFGRIDTLFNCAGGSVAGDTAVDKVDLALWNRTLRLDLDSTML 132 Query: 505 LAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRV 684 + A P +V+ GGG++V +SS A + + AY +K ++ LT+A+A E +RV Sbjct: 133 CCRHAVPAIVRAGGGAVVNMSSGAGLRGSFGGHAYTAAKGAVIALTRALAAEYAPHGVRV 192 Query: 685 NCV 693 N + Sbjct: 193 NAI 195 >UniRef50_Q39TJ1 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Geobacter metallireducens GS-15|Rep: Short-chain dehydrogenase/reductase SDR - Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210) Length = 254 Score = 89.8 bits (213), Expect = 6e-17 Identities = 57/180 (31%), Positives = 82/180 (45%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVA 336 GKVAIVT + G G AIA L GA VV+ SR ++++ + +R+ G V + Sbjct: 10 GKVAIVTGGSRGFGKAIALGLAQAGADVVVASRTQADLDAVAEEIRALGRKSLAVATDML 69 Query: 337 NHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKE 516 + L FG +DIL + TDEQ WD+I DVN+K +L + Sbjct: 70 DRGSIENLAAKTMEAFGKIDILVNNAGQGWTVPFLKWTDEQ-WDQILDVNLKGYFLCTQI 128 Query: 517 AYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVA 696 + K G ++ ISS P + Y SK + +TK +A E I VN +A Sbjct: 129 VGQHMFKAKAGRVINISSAMGSYPLPYMVPYAASKGGINAMTKCLAQEWATRGITVNAIA 188 >UniRef50_Q1VHF4 Cluster: Probable oxidoreductase protein, short-chain dehydrogenase-reductase (SDR) family; n=1; Psychroflexus torquis ATCC 700755|Rep: Probable oxidoreductase protein, short-chain dehydrogenase-reductase (SDR) family - Psychroflexus torquis ATCC 700755 Length = 245 Score = 89.8 bits (213), Expect = 6e-17 Identities = 57/189 (30%), Positives = 97/189 (51%), Gaps = 2/189 (1%) Frame = +1 Query: 136 IQSTRFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVE 315 ++ + + KVAIVT T GIG AIA LG GA +V+ SR + G + SL+ G V Sbjct: 3 LERFKITDKVAIVTGGTRGIGLAIAHALGEAGAKLVVTSRTDKFGG--LDSLKEAGHDVS 60 Query: 316 GVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKS 495 + + +++ + K G +DIL + + ++++ DKI ++NV S Sbjct: 61 FFESDITDKSVPQKIIDYTLDKHGVIDIL-VNNAGVAQHGEMEEFNDELLDKIMNINVDS 119 Query: 496 SWLLAKEAYPELVKRGGGSIVFISSIAAYQPT--EPLGAYGVSKTTLLGLTKAIANETVH 669 + + + + K+G G I+ I SI+ +P AY SK + +TK++A++ Sbjct: 120 VFRMCRSVLTPMKKQGSGVILNIGSISGLVSNIPQPQVAYNASKAAVHMMTKSLASDFAD 179 Query: 670 ENIRVNCVA 696 +NIRVN +A Sbjct: 180 QNIRVNAIA 188 >UniRef50_Q1AYK3 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain dehydrogenase/reductase SDR precursor - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 259 Score = 89.8 bits (213), Expect = 6e-17 Identities = 61/183 (33%), Positives = 92/183 (50%), Gaps = 3/183 (1%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVIC---SRKESNVGKAVQSLRSEGITVEGVV 324 +GK A+VT + GIG AIA L GA V + + + VG+ ++ R V G + Sbjct: 5 AGKRALVTGAGMGIGQAIAVELARCGADVAVHYAHTPPDETVGEVERAGR-RAHPVRGDL 63 Query: 325 CHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWL 504 V E R+ E A GG+D+L LDTDE+ +D IFD+N+K + Sbjct: 64 SRVPECE---RVVEEAAEALGGLDVLVNNAGITRALD-FLDTDEETYDAIFDLNMKGYFF 119 Query: 505 LAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRV 684 A+ A P +++ GGGSIV I+S+ + AY +K ++ T+ +A E IRV Sbjct: 120 CARSAVPHMLEAGGGSIVNITSVHGFAGFPHHTAYAATKGAIIAFTRQLAIELAGRGIRV 179 Query: 685 NCV 693 N + Sbjct: 180 NAI 182 >UniRef50_Q0LQE1 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: Short-chain dehydrogenase/reductase SDR precursor - Herpetosiphon aurantiacus ATCC 23779 Length = 254 Score = 89.8 bits (213), Expect = 6e-17 Identities = 48/182 (26%), Positives = 87/182 (47%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 R V I+T + G+G A+A R +EGA +V+ + AV ++++ G V G Sbjct: 2 RLHDNVVIITGAASGMGLAMATRFAAEGAKLVLGDWNAQRLEAAVATIQASGAAVVGAQG 61 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 ++A+ L ++A S +G +D+L + + + +W ++ +N++ Sbjct: 62 NIADQATAEALVDLAISSYGQLDVLCNNAGVMDSMQGVAEVSDDMWRRVLGINLEGPMFT 121 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 ++ A +++RG G IV ++S A AY SK L+GLT+ A NIR N Sbjct: 122 SRRALKYMLERGSGVIVNVASTAGIHGGSAGAAYTASKHALVGLTRNTAWIYAKRNIRCN 181 Query: 688 CV 693 + Sbjct: 182 AI 183 >UniRef50_Q04DL8 Cluster: Acetoin reductase; n=2; Oenococcus oeni|Rep: Acetoin reductase - Oenococcus oeni (strain BAA-331 / PSU-1) Length = 257 Score = 89.8 bits (213), Expect = 6e-17 Identities = 59/180 (32%), Positives = 92/180 (51%), Gaps = 2/180 (1%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 + KVAIVT +GIG IA RL +G SV+I R + + K + +++ V V V Sbjct: 2 TNKVAIVTGGGQGIGRGIALRLSKDGYSVIINGRTQEKLDKVAEEIKNNNGKVITFVGDV 61 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 ++ +L + A S+FG +D+ +QV D + ++N+KS + A Sbjct: 62 SSKSANEQLVKKAESEFGRLDVFVANAGIDWVDTIEGTPADQV-DNVININLKSQ-IWAL 119 Query: 514 EAYPELVKRG--GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 + P+++++ GGSIV SSIA + E LG Y +K GL +A A E + IRVN Sbjct: 120 QTAPKVMRKSGDGGSIVLASSIAGMEGFEMLGIYSATKFATRGLVQAAAKELAVDKIRVN 179 >UniRef50_A7GTG0 Cluster: Amino acid adenylation domain; n=2; Firmicutes|Rep: Amino acid adenylation domain - Bacillus cereus subsp. cytotoxis NVH 391-98 Length = 2031 Score = 89.8 bits (213), Expect = 6e-17 Identities = 56/178 (31%), Positives = 88/178 (49%) Frame = +1 Query: 160 KVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVAN 339 KVAIVT GIG AIA + EGASV I SR E + + +R GI + + Sbjct: 1786 KVAIVTGGGRGIGRAIAISMAQEGASVAIVSRTEHQLDETACEIRKLGIEPLVIPGDIGE 1845 Query: 340 HEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKEA 519 + + + + +FG +DI+ + D + W +I VNV ++ + + Sbjct: 1846 WNDVQHIVKTVSKQFGKIDIV-VNNAGITKVGSVTDVTSEEWKEIIRVNVFGTYHMCRAT 1904 Query: 520 YPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 P L+++ G I+ I S +++ + AY SK +LGLTK++A E NI+VN V Sbjct: 1905 IPYLIEQKCGKIINIGSDSSFIGYPFMSAYAASKHGVLGLTKSLAEEMKPYNIQVNAV 1962 >UniRef50_A6UFI1 Cluster: Short-chain dehydrogenase/reductase SDR; n=6; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Sinorhizobium medicae WSM419 Length = 259 Score = 89.8 bits (213), Expect = 6e-17 Identities = 53/185 (28%), Positives = 91/185 (49%) Frame = +1 Query: 142 STRFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGV 321 S R GK +VT + +GIG AIA+ SEGA++++ R + + L+ +G + Sbjct: 2 SARLQGKRIMVTGAAQGIGLAIAEVFLSEGAALLLVDRDGPLLEREASRLQEQGWELVYA 61 Query: 322 VCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSW 501 + + + A + G ++ L + +D W + FDVN++ +W Sbjct: 62 QADITDAQAISVAVSSAATSIGRINALVNNAGINVFSEPLAMSDAD-WQRCFDVNLRGAW 120 Query: 502 LLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIR 681 K P L+++GGG+I+ I+S A+ Y V+K LLG+TKA+ E + +R Sbjct: 121 NCCKAVLPNLIEQGGGAILNIASTHAFTIIPHTFPYPVAKHALLGMTKALGIEYASKGVR 180 Query: 682 VNCVA 696 VN +A Sbjct: 181 VNALA 185 >UniRef50_A5VEF2 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Sphingomonas wittichii RW1|Rep: Short-chain dehydrogenase/reductase SDR - Sphingomonas wittichii RW1 Length = 263 Score = 89.8 bits (213), Expect = 6e-17 Identities = 54/178 (30%), Positives = 83/178 (46%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 +GK AIVT + G G AIA+ L + GA V +R E + + V + ++G + V Sbjct: 15 NGKGAIVTGAGRGCGRAIARGLAAAGARVCCAARSEKELAETVALIEADGGSAMAFAVDV 74 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 + + E AT+ FGG+D+L I D W + +VN+ S+ + Sbjct: 75 TDLAAVEAMTETATAAFGGLDLLVLSHGVALAVAPIEGGDPADWRRTIEVNLIGSYHCIR 134 Query: 514 EAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 A P + RG G I+ + S + T AY SK LT+++A E + NI VN Sbjct: 135 AAVPPMKARGAGKIIVVGSGQGHNGTAATSAYASSKAGTWALTRSVAAELIGFNISVN 192 >UniRef50_A4AAT7 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; unclassified Gammaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Congregibacter litoralis KT71 Length = 254 Score = 89.8 bits (213), Expect = 6e-17 Identities = 54/178 (30%), Positives = 79/178 (44%) Frame = +1 Query: 160 KVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVAN 339 K I+T I A+R GA V++ ES++ R + + V V + Sbjct: 7 KTVILTGGAGDIAKVAARRFVDAGAKVMLVDLDESSLRDIASECREDDLRY--TVADVTS 64 Query: 340 HEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKEA 519 FGGVD+L + + D Q + K+ DVNV +L K Sbjct: 65 ETDTAAYVAATVGAFGGVDVLLANAGVEGPSAPVSEFDLQSFQKVLDVNVMGVFLGIKHV 124 Query: 520 YPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 +P + GGGS+V SS+A T + AYG SK ++GL +A A E +NIRVN + Sbjct: 125 FPVMAAGGGGSVVITSSVAGVSATPGICAYGTSKHAVIGLMRACAKEGGPQNIRVNTI 182 >UniRef50_A3JWC2 Cluster: Dehydrogenase; n=1; Rhodobacterales bacterium HTCC2150|Rep: Dehydrogenase - Rhodobacterales bacterium HTCC2150 Length = 279 Score = 89.8 bits (213), Expect = 6e-17 Identities = 56/193 (29%), Positives = 96/193 (49%), Gaps = 1/193 (0%) Frame = +1 Query: 109 STSANPVRAIQSTRFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQS 288 ST PV+ + + K IVT + +G+GYA A R +GA+VV+ + ++VQ Sbjct: 8 STICWPVKQEATMKLKNKTVIVTGAAQGLGYACALRFLQDGANVVMADVNAEKLAESVQD 67 Query: 289 LRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWD 468 L V +VC V E+ + L +A S +G +D++ + +D++ +D Sbjct: 68 LIEFDGAVSSMVCDVTKRENLQALVGLAVSNYGNLDVMINNAGIAKVQDFLEISDDE-YD 126 Query: 469 KIFDVNVKSSWLLAKEAYPELVKRG-GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTK 645 + DVN++ +++ + A +++ +G GG I+ +SSI A L Y +SK + LT Sbjct: 127 AVMDVNLRGAFIGTQIAGKQMIAQGKGGVIINMSSINALVANPMLSTYAISKGGMNQLTN 186 Query: 646 AIANETVHENIRV 684 A NIRV Sbjct: 187 IAAVGLAPHNIRV 199 >UniRef50_A1WLZ9 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Verminephrobacter eiseniae EF01-2|Rep: Short-chain dehydrogenase/reductase SDR precursor - Verminephrobacter eiseniae (strain EF01-2) Length = 252 Score = 89.8 bits (213), Expect = 6e-17 Identities = 56/180 (31%), Positives = 87/180 (48%), Gaps = 1/180 (0%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVA 336 GK A VT + GIG A A GA V++ R ES + A+ +LR G +VC V Sbjct: 5 GKTAFVTGAGSGIGQATAMAFAQAGAWVLLVDRDESALAGALAALRQGGGQGATMVCDVR 64 Query: 337 NHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSW-LLAK 513 + R A + G +D +LD DE +++++ D+N++ W L Sbjct: 65 QGDAVRAAVACAVQQRGALDCAVNAAGVEGASKTLLDEDEALFEQVMDINLRGVWHCLRA 124 Query: 514 EAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 + L +R GG+IV I+S A + AY SK +LGLT++ A + + +R+N V Sbjct: 125 QIGQMLSQRAGGAIVNIASAAGLVGSRRCAAYSASKHGVLGLTRSAALQYGGQRVRINAV 184 >UniRef50_A1B0V7 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=6; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR precursor - Paracoccus denitrificans (strain Pd 1222) Length = 253 Score = 89.8 bits (213), Expect = 6e-17 Identities = 62/181 (34%), Positives = 90/181 (49%), Gaps = 2/181 (1%) Frame = +1 Query: 160 KVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSE-GITVEGVVCHVA 336 KV ++T + GIG A AK EGA VV+ +G A + + +E G V+ Sbjct: 8 KVVLITGAGAGIGAATAKLFIEEGARVVVADY----LGDAAEQVAAELGENARAFTVDVS 63 Query: 337 NHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKE 516 E + + + ++FGG+D+L + DE W I DVN+ +L +K Sbjct: 64 KAEACKAMVDFTVAEFGGLDVLVNNAGRGSLGT-VETQDENDWRSIIDVNLTGVYLCSKY 122 Query: 517 AYPELVKRGGGSIV-FISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 A PEL KRGGG+IV S+IA AY +K + LT+A+A + +NIRVN V Sbjct: 123 AVPELRKRGGGAIVNTASNIAMAMAIRDRAAYVAAKGGVASLTRAMALDFAADNIRVNSV 182 Query: 694 A 696 A Sbjct: 183 A 183 >UniRef50_A0QXD6 Cluster: L-xylulose reductase; n=2; Actinomycetales|Rep: L-xylulose reductase - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 262 Score = 89.8 bits (213), Expect = 6e-17 Identities = 61/184 (33%), Positives = 91/184 (49%), Gaps = 2/184 (1%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSE-GITVEGVV 324 R GK A++T +T+GIG IA+ + GA +V+ R S + A ++L + G V V Sbjct: 13 RLDGKRALITGATKGIGADIARAFAAAGARLVLSGRDVSELDAARRALGEQFGTDVHTVA 72 Query: 325 CHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWL 504 +A + L A FGG+D+L ++DTD Q++D VN+++ L Sbjct: 73 IDLAEPDAPAELARRAAEAFGGLDVLVNNAGISHPQP-VVDTDPQLFDATIAVNLRAPAL 131 Query: 505 LAKEAYPELVKRG-GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIR 681 LA +V G GG+I+ ++S AA P AY SK L+ TK +A E IR Sbjct: 132 LASAVGKAMVAAGEGGAIITVASAAALAPLPDHYAYCTSKAGLVMATKVLARELGPHGIR 191 Query: 682 VNCV 693 N V Sbjct: 192 ANSV 195 >UniRef50_A5A7R3 Cluster: 17beta-hydroxysteroid dehydrogenase type 8; n=1; Branchiostoma belcheri|Rep: 17beta-hydroxysteroid dehydrogenase type 8 - Branchiostoma belcheri (Amphioxus) Length = 258 Score = 89.8 bits (213), Expect = 6e-17 Identities = 54/185 (29%), Positives = 91/185 (49%), Gaps = 3/185 (1%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 R +GK+A+VTA GIG A+ + EGA VV+ + + SL + + V Sbjct: 8 RLTGKLALVTAGGGGIGRAVCQAFAREGAKVVVSDINGTTAKDTLSSLEGDPSSHRDYVA 67 Query: 328 HVANHEHRRRLFEVATSKF-GGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWL 504 V++ E +++F+ ++ D++ +L+ E V+D +VNVK ++L Sbjct: 68 DVSSSEDVQKMFDFVCHEYKAAPDVVAQIAGGCKAIGPLLELSEDVFDHAMNVNVKGTFL 127 Query: 505 LAKEAYPELVKRG--GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENI 678 + + A ++K GSI+ + S+AA P E L YG +K ++ LT+ A E I Sbjct: 128 VVQAAARAMLKHNVQNGSIITVGSLAANTPEETLSHYGAAKAGVVQLTRTAALELAPHGI 187 Query: 679 RVNCV 693 R N V Sbjct: 188 RCNAV 192 >UniRef50_A2QS57 Cluster: Contig An08c0220, complete genome; n=2; cellular organisms|Rep: Contig An08c0220, complete genome - Aspergillus niger Length = 253 Score = 89.8 bits (213), Expect = 6e-17 Identities = 61/182 (33%), Positives = 90/182 (49%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 R K+AIVT G G I + EGA+VVI + N GK VQ + +G V V Sbjct: 5 RLQDKIAIVTGGGFGFGEGIVHKFILEGANVVIVDLDQEN-GKRVQCAQPKGRAVF-VQG 62 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 V++ R+ EVA F +DI+ L+T E + D+++ VNVKS + Sbjct: 63 DVSSESDWERVREVALENFKKIDIVVNNAGIVHVVQPSLETSETMLDRMYKVNVKSIYHS 122 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 AK P +GGG V ISS+++ +P Y +K + TK++A E + +IR+N Sbjct: 123 AKTIAPYFQAQGGGVFVNISSMSSIRPRPKYAWYSATKGAVSAATKSLAAEFANNHIRLN 182 Query: 688 CV 693 V Sbjct: 183 TV 184 >UniRef50_Q8EMP9 Cluster: 3-oxoacyl-(Acyl carrier protein) reductase; n=10; Firmicutes|Rep: 3-oxoacyl-(Acyl carrier protein) reductase - Oceanobacillus iheyensis Length = 263 Score = 89.4 bits (212), Expect = 7e-17 Identities = 54/181 (29%), Positives = 90/181 (49%), Gaps = 2/181 (1%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSE--GITVEGVVCH 330 GK IV AS++G+G A AK+ +EGA V+I SR + + KA + +RSE V +VC Sbjct: 7 GKSVIVAASSKGLGKATAKQFAAEGAKVIISSRSQEELEKAQEEIRSETGNNNVSYIVCD 66 Query: 331 VANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLA 510 + N + L +D+L D ++ W F++N+ S L Sbjct: 67 ITNPASVKELVVKTIELNETIDVL-VNNAGGPPAGNFDDVSDEEWTNAFELNLLSFVRLI 125 Query: 511 KEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNC 690 +E P + ++G G IV I+S + QP + L + ++GL K+++ E +NI +N Sbjct: 126 REVLPYMRRQGSGHIVNIASSSIKQPIDNLILSNTFRAGIVGLAKSLSQELAPDNILINT 185 Query: 691 V 693 + Sbjct: 186 I 186 >UniRef50_Q7NCW8 Cluster: Gll2858 protein; n=6; Bacteria|Rep: Gll2858 protein - Gloeobacter violaceus Length = 268 Score = 89.4 bits (212), Expect = 7e-17 Identities = 55/178 (30%), Positives = 87/178 (48%) Frame = +1 Query: 160 KVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVAN 339 KVAIVT ++ GIG A A L GA VV +R+ + V+++R+EG V V + Sbjct: 24 KVAIVTGASSGIGRATALELARRGAKVVASARRVGPTLELVEAIRAEGHEATFVQADVTD 83 Query: 340 HEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKEA 519 + RL A + +G +DI +L+ ++ +D +FD NV+S + K Sbjct: 84 EAYVERLVAEAIATYGKLDIAFNNAGTEGVFAPLLEQTKETYDLVFDANVRSVFYSMKHQ 143 Query: 520 YPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 ++ GGG IV +S+ E Y +K +LG+TK+ A E +RVN + Sbjct: 144 AQAMLCAGGGVIVNNASMGGVIGFENAALYIATKHAVLGMTKSAALEWYRRGVRVNAI 201 >UniRef50_Q4JXS5 Cluster: Dehydrogenase related to short-chain alcohol dehydrogenases; n=3; Corynebacterineae|Rep: Dehydrogenase related to short-chain alcohol dehydrogenases - Corynebacterium jeikeium (strain K411) Length = 290 Score = 89.4 bits (212), Expect = 7e-17 Identities = 63/195 (32%), Positives = 96/195 (49%), Gaps = 13/195 (6%) Frame = +1 Query: 151 FSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRS-------EGIT 309 ++G IVT T GIG+A A +L + GA+VVI RK VG A + L++ + Sbjct: 6 YAGLTVIVTGGTRGIGHATALQLAASGANVVITGRKPETVGPAAEELQAAARKQNPDAGR 65 Query: 310 VEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNV 489 V G+ HVA+ E ++ A +FG +D+L + ++ K+F +N Sbjct: 66 VIGIAAHVADPEAAKKACTQAVEEFGRLDVLINNAGTNPAFGPVHKQSAEIMTKVFQINT 125 Query: 490 KSS--WLLAK-EA-YPELVKRGG--GSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAI 651 W A EA + + GG G++V +SSI A + +G Y SK LL LTK + Sbjct: 126 IGPVIWTSAAIEADLGKAARNGGPAGAVVNVSSIGALSMEDYIGVYNASKAALLHLTKQM 185 Query: 652 ANETVHENIRVNCVA 696 A E + IRVN ++ Sbjct: 186 ARE-LAPRIRVNSIS 199 >UniRef50_Q2CH74 Cluster: Short-chain alcohol dehydrogenase; n=1; Oceanicola granulosus HTCC2516|Rep: Short-chain alcohol dehydrogenase - Oceanicola granulosus HTCC2516 Length = 245 Score = 89.4 bits (212), Expect = 7e-17 Identities = 58/182 (31%), Positives = 88/182 (48%), Gaps = 1/182 (0%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEG-ITVEGVVCH 330 +GK +VT + +GIG A A+ GA +V+ R + +A G + VE V Sbjct: 6 AGKCILVTGAGDGIGRAAARLFAEAGAHLVLVDRHGA---QATADAHCPGALAVEMDVRD 62 Query: 331 VANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLA 510 A + RL AT++FGG+D L + D E++WD I D+N K WL Sbjct: 63 GAGWD---RLVAEATARFGGIDALVNNAGIAVPGDTVTDASEEMWDDILDINAKGVWLGM 119 Query: 511 KEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNC 690 + P +V+RGGG I ++S AA+ AY SK +L LT+ + I++N Sbjct: 120 RAVLPGMVERGGGHICNVASTAAHIGLPGAAAYCASKGAVLALTRQAGVQYAPLGIKINS 179 Query: 691 VA 696 V+ Sbjct: 180 VS 181 >UniRef50_Q026E7 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Solibacter usitatus Ellin6076|Rep: Short-chain dehydrogenase/reductase SDR - Solibacter usitatus (strain Ellin6076) Length = 251 Score = 89.4 bits (212), Expect = 7e-17 Identities = 52/185 (28%), Positives = 93/185 (50%) Frame = +1 Query: 142 STRFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGV 321 S + +VA++T +++G+G A+A L +EG + + SR E+ + + L + G Sbjct: 2 SGKLKDRVAVITGASKGLGKAMAMALAAEGTRIALVSRDEARLNEVAAELIAAGGDAAIF 61 Query: 322 VCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSW 501 V + E R+ + +G VDIL + T E+ W ++ D NV +++ Sbjct: 62 RADVTSEEQVRQAERAILATYGKVDILINNAGVNVRKPVVEFTVEE-WHRVMDTNVTAAF 120 Query: 502 LLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIR 681 L+ + P + RG G I+ ++SI ++ AY SKT LLG+T+ +A E + I Sbjct: 121 LMCRSFVPAMSGRGYGRILNMTSIMSHVSLPGRIAYSTSKTALLGMTRTLALELAPQGIT 180 Query: 682 VNCVA 696 VN ++ Sbjct: 181 VNGIS 185 >UniRef50_A1WNV5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Verminephrobacter eiseniae EF01-2|Rep: Short-chain dehydrogenase/reductase SDR - Verminephrobacter eiseniae (strain EF01-2) Length = 261 Score = 89.4 bits (212), Expect = 7e-17 Identities = 47/183 (25%), Positives = 93/183 (50%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 R GK A++T + +GIG+AIA+ + EGA V + ++ + LR+ G + + C Sbjct: 3 RLEGKTAVITGAADGIGHAIAQAMAREGAHVFLSDISDAQGERCAAQLRAAGHLADYLHC 62 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 VA + RL + A + G +D++ + + ++ W ++ ++N+ S + Sbjct: 63 DVAKADDIARLVDTAVRQTGHLDVMVNNAAIAIGGMPVHEMTDEQWQRLIEINLTSVFRG 122 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 K A P ++ + GSI+ ++S + + AY +K ++ +T+ +A E NIRVN Sbjct: 123 CKCALPHMIAQKSGSIINMASAQGHIGLDGWTAYAGAKGAVMAMTRQMAVEFGPVNIRVN 182 Query: 688 CVA 696 ++ Sbjct: 183 SIS 185 >UniRef50_Q8U3B3 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=3; cellular organisms|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Pyrococcus furiosus Length = 260 Score = 89.4 bits (212), Expect = 7e-17 Identities = 58/179 (32%), Positives = 85/179 (47%) Frame = +1 Query: 160 KVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVAN 339 KVAIVT +GIG AIA+ GA VV+ E + LR G+ V + VA+ Sbjct: 9 KVAIVTGGGQGIGAAIAQLFAENGAKVVLAEIDEEAGLEREAMLRERGLDVTFIKTDVAD 68 Query: 340 HEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKEA 519 E + + + +GGVDIL T E+ W+++ VN+ ++ ++ A Sbjct: 69 EESVKNMVKKTVELYGGVDILVNNAAIMSVKSIFERTLEE-WERVIRVNLTGPYICSRYA 127 Query: 520 YPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVA 696 E++KRGGG I+ I+S A Y SK LL LT ++A IRV V+ Sbjct: 128 AEEMIKRGGGVIINIASTRALMSEPDTEPYSASKGGLLALTHSLAISLAKYRIRVVAVS 186 >UniRef50_Q65F37 Cluster: Putative uncharacterized protein; n=1; Bacillus licheniformis ATCC 14580|Rep: Putative uncharacterized protein - Bacillus licheniformis (strain DSM 13 / ATCC 14580) Length = 248 Score = 89.0 bits (211), Expect = 1e-16 Identities = 57/182 (31%), Positives = 87/182 (47%), Gaps = 1/182 (0%) Frame = +1 Query: 151 FSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCH 330 F+ + AI+T ++ GIG AIA+ L +GA+VVI E + L +E V Sbjct: 3 FNQQTAIITGASRGIGRAIAELLADKGANVVINGTNEELLKSLCTQLNTERKCASYVAGD 62 Query: 331 VANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLA 510 + E L A +FG +DIL + DT + W ++ D+N+ ++L+ Sbjct: 63 ASLPETASLLIAEAKQRFGRIDILVNNAGVNLRKTTV-DTSLEEWKRVIDLNLTGTFLMC 121 Query: 511 KEAYPELVKRGGGSIVFISSIAAYQPTEPLG-AYGVSKTTLLGLTKAIANETVHENIRVN 687 + PE++ +GGG IV +SS + P AYG SK + LT +A E I VN Sbjct: 122 QAVIPEMITQGGGKIVNMSSTTSKTPHHNASPAYGASKAGINYLTMHLAKELAEHRIHVN 181 Query: 688 CV 693 V Sbjct: 182 GV 183 >UniRef50_Q39YK9 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Geobacter metallireducens GS-15|Rep: Short-chain dehydrogenase/reductase SDR - Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210) Length = 259 Score = 89.0 bits (211), Expect = 1e-16 Identities = 56/177 (31%), Positives = 80/177 (45%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVA 336 GK AIVT + G+G A A L EGA +VI SR + + + G TV VA Sbjct: 5 GKTAIVTGAGRGLGRASAMALAREGADLVILSRTPKELEETATLVMEAGGTVVIQEGDVA 64 Query: 337 NHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKE 516 N RR+ A F VDIL + + W VN+ WL A+E Sbjct: 65 NPADVRRVVGTAVETFESVDILMNNAAVIGPVRALHQLAPEEWAYAMAVNLTGPWLFARE 124 Query: 517 AYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 P ++++ G I+ + S P GAY ++K L+ +T+ +A E NI+VN Sbjct: 125 VIPHMIRQKRGKIINVISGLGEIVISPFGAYAIAKAGLIHMTRYLAEELKVHNIQVN 181 >UniRef50_Q9RLV7 Cluster: Diacetyl(Acetoin) reductase; n=4; Lactobacillales|Rep: Diacetyl(Acetoin) reductase - Lactococcus lactis Length = 256 Score = 89.0 bits (211), Expect = 1e-16 Identities = 55/178 (30%), Positives = 89/178 (50%), Gaps = 1/178 (0%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVA 336 GK+AIVT S +GIG I RL +G +V + ++L +G + V VA Sbjct: 2 GKLAIVTGSGQGIGEGIVYRLAKDGFAVAVADINPQTAKNVAKTLIDKGFEAKAYVLDVA 61 Query: 337 NHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKE 516 N +L E A S FG + + I+D+D + +++FDVN+K ++ + Sbjct: 62 NRSAVFQLIEQAVSDFGELAVF-VNNAGVAFIDSIIDSDSERVERLFDVNIKGTYWGIQA 120 Query: 517 AYPELVKRG-GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 A + K+G GG I+ +S+A+ + + AY SK + GLT++ A E + I VN Sbjct: 121 AATQFKKQGHGGRIINAASLASVEGSALQSAYSASKFAIRGLTQSAAKELAKDYITVN 178 >UniRef50_Q8GR61 Cluster: Xylitol dehydrogenase; n=2; Gluconobacter oxydans|Rep: Xylitol dehydrogenase - Gluconobacter oxydans (Gluconobacter suboxydans) Length = 262 Score = 89.0 bits (211), Expect = 1e-16 Identities = 50/185 (27%), Positives = 86/185 (46%) Frame = +1 Query: 142 STRFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGV 321 S +F+GKV +VT + IG A A RL EG ++ + + KA S+R +G+ Sbjct: 2 SKKFNGKVCLVTGAGGNIGLATALRLAEEGTAIALLDMNREALEKAEASVREKGVEARSY 61 Query: 322 VCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSW 501 VC V + E + FG +D L + D + ++ +NV ++ Sbjct: 62 VCDVTSEEAVIGTVDSVVRDFGKIDFLFNNAGYQGAFAPVQDYPSDDFARVLTINVTGAF 121 Query: 502 LLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIR 681 + K +++ + G IV +S+A + + AYG SK ++ LT+ A + NIR Sbjct: 122 HVLKAVSRQMITQNYGRIVNTASMAGVKGPPNMAAYGTSKGAIIALTETAALDLAPYNIR 181 Query: 682 VNCVA 696 VN ++ Sbjct: 182 VNAIS 186 >UniRef50_Q1NH65 Cluster: Dehydrogenase; n=1; Sphingomonas sp. SKA58|Rep: Dehydrogenase - Sphingomonas sp. SKA58 Length = 275 Score = 89.0 bits (211), Expect = 1e-16 Identities = 56/185 (30%), Positives = 83/185 (44%), Gaps = 5/185 (2%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVA 336 G+VAIVT + +GIG +A L GA+V++ V A SLR + + E + Sbjct: 7 GRVAIVTGAAQGIGLEVATVLAERGATVILSDILADRVEAAADSLRGKNLRAEAETFDLT 66 Query: 337 NHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTD-----EQVWDKIFDVNVKSSW 501 + + + G +DIL LD D WDK F VN + Sbjct: 67 DEDSVSAAVARIAGRHGRIDILHNNAAYQTTEQRRLDRDVVHLDTGAWDKAFAVNARGPM 126 Query: 502 LLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIR 681 LL K A P ++ GGGS++ +S L AYG SK L+ L++ +A + + IR Sbjct: 127 LLCKHALPVMIAGGGGSLIHSASGFGLLGEMTLTAYGASKAALINLSRFLATQYGKQGIR 186 Query: 682 VNCVA 696 N +A Sbjct: 187 SNVIA 191 >UniRef50_Q11C03 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Mesorhizobium sp. BNC1|Rep: Short-chain dehydrogenase/reductase SDR - Mesorhizobium sp. (strain BNC1) Length = 257 Score = 89.0 bits (211), Expect = 1e-16 Identities = 49/181 (27%), Positives = 88/181 (48%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 SGKVA+VT + G+G AIA L ++GA V + + + ++++ C + Sbjct: 5 SGKVALVTGAARGLGEAIAVELAAQGARVALLDVLDELGAEVAENIKKSSGNAYYRNCDI 64 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 + E R + S +G +D+L I + E+ W+ IF+VNV S + + Sbjct: 65 RDTEEVRSAVDEVYSTYGKLDVLVNNAAVSTAPTSIPELSEETWNNIFNVNVSSIYRFCR 124 Query: 514 EAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 P + + GGG+++ +SS+ AY +K ++ +++ +A E NIRVN V Sbjct: 125 FVLPRMQEAGGGAVINMSSVHQSHSLTGWTAYAATKGAIISMSRQLAAEWGRFNIRVNTV 184 Query: 694 A 696 + Sbjct: 185 S 185 >UniRef50_A5FBH9 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Flavobacterium johnsoniae UW101|Rep: Short-chain dehydrogenase/reductase SDR precursor - Flavobacterium johnsoniae UW101 Length = 250 Score = 89.0 bits (211), Expect = 1e-16 Identities = 52/183 (28%), Positives = 88/183 (48%), Gaps = 1/183 (0%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQS-LRSEGITVEGVV 324 + + K A++T S G+G AIA+R + GA +VI K+ AV S +++ G+ V Sbjct: 3 KLNNKTAVITGSVRGLGKAIAERYAAMGADIVINYSKDKASADAVLSTIKAMGVKAIAVQ 62 Query: 325 CHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWL 504 V+ RLF A + FG +DI+ + + E+ +DK+F +N K ++ Sbjct: 63 ADVSKVADLERLFAEAKAAFGKIDIVVANAGIEMVEVPVTEFTEEQFDKVFSINTKGTYF 122 Query: 505 LAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRV 684 ++A + G I++I+S P + YG SKTT L ++ E H + V Sbjct: 123 TLQQAAKHI--EDNGRIIYIASSTTSFPVPGMAVYGGSKTTPRYLVDILSKEIGHRGVTV 180 Query: 685 NCV 693 N + Sbjct: 181 NSI 183 >UniRef50_A4AN22 Cluster: Probable glucose 1-dehydrogenase; n=1; Flavobacteriales bacterium HTCC2170|Rep: Probable glucose 1-dehydrogenase - Flavobacteriales bacterium HTCC2170 Length = 268 Score = 89.0 bits (211), Expect = 1e-16 Identities = 63/183 (34%), Positives = 93/183 (50%), Gaps = 3/183 (1%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVIC--SRKESNVGKAVQSLRSEGITVEGVVC- 327 GK +VT + GIG I ++L + GA V I S ++S A + S G+ G+ C Sbjct: 8 GKRVLVTGGSRGIGAEICRKLAACGAEVFINYNSNEQSAQDLANEISNSYGVRT-GIACA 66 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 V+ E +++F GG+DIL +LD E+ WD++ +VN+K +L Sbjct: 67 DVSKAEQVKQMFLKMDGVMGGIDILVNNAGTESIHH-VLDLVEEEWDRVINVNLKGPFLC 125 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 +KEA + K GGG I+ ISSI P + L Y +K L L+K ++ E NIRV Sbjct: 126 SKEAGDRMEKNGGGVIINISSIHDVVPRKGLIHYCSAKAGLKMLSKCLSLELAENNIRVV 185 Query: 688 CVA 696 VA Sbjct: 186 SVA 188 >UniRef50_A3IK59 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein; n=2; Chroococcales|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein - Cyanothece sp. CCY 0110 Length = 250 Score = 89.0 bits (211), Expect = 1e-16 Identities = 46/185 (24%), Positives = 95/185 (51%), Gaps = 2/185 (1%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 + + K+A++T ++ GIG AIA RL E +V+C+R++ + K ++LR + + + Sbjct: 5 KLTSKIALITGASSGIGEAIAYRLVEENYRLVVCARRQEKLNKLTETLREKNSKILSLKV 64 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 + +F K+GGVD+L ++ + + W ++ +VNV + + Sbjct: 65 DLRQEAEIMNMFNTIRDKWGGVDVLINNAGLGHKEPLMIG-ETEAWREMLEVNVLALCIC 123 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANE--TVHENIR 681 +EA ++ R G I+ ISS++ ++ G Y SK + LT+ + E ++NI+ Sbjct: 124 TREAIKDMSDRNEGHIIHISSMSGHRVPLYSGVYAASKYAVRALTEGLRQELREANKNIK 183 Query: 682 VNCVA 696 ++ ++ Sbjct: 184 ISSIS 188 >UniRef50_Q5BII6 Cluster: RH05486p; n=4; Sophophora|Rep: RH05486p - Drosophila melanogaster (Fruit fly) Length = 255 Score = 89.0 bits (211), Expect = 1e-16 Identities = 60/180 (33%), Positives = 93/180 (51%) Frame = +1 Query: 154 SGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHV 333 S KV IVT ++ GIG AIA+ L EGA++ + R +N+ +SL+ G E VV V Sbjct: 8 SNKVVIVTGASSGIGAAIAQVLAREGATLALVGRNVANLEATKKSLK--GTQAEIVVADV 65 Query: 334 ANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAK 513 + + + +KFG +D+L ++D D + +D + + N++ LL K Sbjct: 66 T--KDADAIVQQTLAKFGRIDVL-VNNAGILGKGGLIDLDIEEFDAVLNTNLRGVILLTK 122 Query: 514 EAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCV 693 P L+K G++V +SS A +P +YGVSK L TK +A E + +RVN V Sbjct: 123 AVLPHLLKT-KGAVVNVSSCAGIRPFAGALSYGVSKAALDQFTKIVALEMAPQGVRVNSV 181 >UniRef50_Q9WYG0 Cluster: Uncharacterized oxidoreductase TM_0325; n=2; Thermotoga|Rep: Uncharacterized oxidoreductase TM_0325 - Thermotoga maritima Length = 251 Score = 89.0 bits (211), Expect = 1e-16 Identities = 62/181 (34%), Positives = 88/181 (48%) Frame = +1 Query: 151 FSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCH 330 F GKV ++T + GIG A GA V I E + V+ ++S G + Sbjct: 3 FQGKVVLITGAGSGIGKKAAVMFAERGAKVAINDISEEKGKETVELIKSMGGEAAFIFGD 62 Query: 331 VANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLA 510 VA + ++ + FG +DIL I +T E+ +DK VNVK +LL+ Sbjct: 63 VA--KDAEQIVKKTVETFGRLDILVNNAGIVPYGN-IEETSEEDFDKTMAVNVKGPFLLS 119 Query: 511 KEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNC 690 K A ++ K+GGG IV +SS A Y VSK LLGLT+++A + V IRVN Sbjct: 120 KYAVEQMKKQGGGVIVNVSSEAGLIGIPRRCVYSVSKAALLGLTRSLAVDYVDYGIRVNA 179 Query: 691 V 693 V Sbjct: 180 V 180 >UniRef50_P50198 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=4; Sphingomonas|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Pseudomonas paucimobilis (Sphingomonas paucimobilis) Length = 250 Score = 89.0 bits (211), Expect = 1e-16 Identities = 60/184 (32%), Positives = 85/184 (46%) Frame = +1 Query: 142 STRFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGV 321 + R +GKVA++T G+G A AKR EGA VVI E V +R+ G + Sbjct: 2 ANRLAGKVALITGGASGLGAAQAKRFAEEGAKVVIGDLNEEMAKGVVAEIRAAGGDALFI 61 Query: 322 VCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSW 501 V + A FGG+ L ++ E W+K+ VN + + Sbjct: 62 RLDVTDAASWNNAIAAAVDGFGGLTTLSNTAGIIHPGGFEEESIEG-WNKMVAVNQTAIF 120 Query: 502 LLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIR 681 L K A PELVK G GSI+ ISS+ PT +Y +K + ++KA A E V +R Sbjct: 121 LGIKAAIPELVKSGNGSIINISSLIGMFPTAGNASYCATKAAVRIMSKAAALEFVDRGVR 180 Query: 682 VNCV 693 VN + Sbjct: 181 VNTI 184 >UniRef50_Q98C97 Cluster: 3-oxoacyl-(Acyl carrier protein) reductase; n=5; Alphaproteobacteria|Rep: 3-oxoacyl-(Acyl carrier protein) reductase - Rhizobium loti (Mesorhizobium loti) Length = 249 Score = 88.6 bits (210), Expect = 1e-16 Identities = 51/182 (28%), Positives = 82/182 (45%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 RF+G+ A++T GIG A+A+R+ EG + + R + + +A + + GV Sbjct: 7 RFAGRSAVITGGASGIGLAVAQRIVEEGGRISVWDRDPAQIEQAKTVIPG----LHGVAI 62 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 VA+ GGVDIL + W K+ D+N+ + Sbjct: 63 DVADAAGVEGAAARTIEALGGVDILVTSAAITGPNMTTWAYSTEDWQKVIDININGVFYC 122 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 + P +++R G IV I+SIA + AY SK ++GLTK++ E + VN Sbjct: 123 NRALVPHMLERNYGRIVNIASIAGKEGNPNASAYSTSKAAVIGLTKSLGKELAKTKVTVN 182 Query: 688 CV 693 CV Sbjct: 183 CV 184 >UniRef50_Q47PW7 Cluster: Short-chain alcohol dehydrogenase; n=1; Thermobifida fusca YX|Rep: Short-chain alcohol dehydrogenase - Thermobifida fusca (strain YX) Length = 267 Score = 88.6 bits (210), Expect = 1e-16 Identities = 51/184 (27%), Positives = 84/184 (45%) Frame = +1 Query: 142 STRFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGV 321 S R + K+A++T + G G A A R +EGASVV R A + + G T + Sbjct: 4 SGRLTDKIALITGAGSGFGRASALRFAAEGASVVCVDRNADAAHSAADDIAAAGGTALAL 63 Query: 322 VCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSW 501 V++ R+ FG +DI+ T+E+ WD++ +N+K W Sbjct: 64 TADVSSAADAERMTTTTLEHFGRIDIVFANAGIPGSGDAHTTTEEE-WDRVIAINLKGVW 122 Query: 502 LLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIR 681 L +K A P +V+R G I +S+ + Y +K ++ +T+ +A NIR Sbjct: 123 LTSKYALPHMVERRSGVITNQASVGGLIGIPGIFPYAAAKGGVISMTRQMAAAYAPHNIR 182 Query: 682 VNCV 693 VN + Sbjct: 183 VNAI 186 >UniRef50_Q391K0 Cluster: Short-chain dehydrogenase/reductase SDR; n=9; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 259 Score = 88.6 bits (210), Expect = 1e-16 Identities = 57/183 (31%), Positives = 83/183 (45%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 R +GKVA+V+ G G A ++ ++GA V I R LR G+ G Sbjct: 8 RLAGKVAVVSGGAGGCGGAASELFAAQGAKVAIIDRDGDAAETLASRLRDAGLQAIGFGA 67 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 V+ ++ A ++G DIL LD +E WD + VNVKS +L+ Sbjct: 68 DVSKQAEVQQAVNAAREQYGNADILFNHAGTLIVKP-FLDIEESEWDWLMGVNVKSMFLM 126 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 K P+++++G GSIV SSI+A T Y +K +AIA E IR N Sbjct: 127 TKAVLPQMLEKGRGSIVCTSSISAVCATPGEVLYDATKGACHMFARAIAVEYRDRGIRCN 186 Query: 688 CVA 696 +A Sbjct: 187 ALA 189 >UniRef50_Q52JK0 Cluster: PhaB; n=16; Bacteria|Rep: PhaB - Bacillus thuringiensis Length = 247 Score = 88.6 bits (210), Expect = 1e-16 Identities = 63/184 (34%), Positives = 85/184 (46%), Gaps = 2/184 (1%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVI--CSRKESNVGKAVQSLRSEGITVEGV 321 + +GKVAIVT +GIG AI L EGA VVI S KE+ V L EG V V Sbjct: 3 QLNGKVAIVTGGAKGIGKAITVALAQEGAKVVINYNSSKEA-AENLVNELGKEGHDVYAV 61 Query: 322 VCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSW 501 V+ E RL E A + FG VDIL + + W+++ DVN+ S + Sbjct: 62 QADVSKVEDANRLVEEAVNHFGKVDIL-VNNAGITRDRTFKKLNREDWERVIDVNLSSVF 120 Query: 502 LLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIR 681 P + + G I+ ISSI Y +K +LG TK++A E N+ Sbjct: 121 NTTSAVLPYITEAEEGRIISISSIIGQAGGFGQTNYSAAKAGMLGFTKSLALELAKTNVT 180 Query: 682 VNCV 693 VN + Sbjct: 181 VNAI 184 >UniRef50_Q1AYM3 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain dehydrogenase/reductase SDR - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 250 Score = 88.6 bits (210), Expect = 1e-16 Identities = 54/180 (30%), Positives = 84/180 (46%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVA 336 GKVA+VT G+G I L + GA+V + + + G V V+ Sbjct: 6 GKVAVVTGGGGGLGEGICAGLAAAGAAVAAVDVDLEKARRVERLVAGRGGRCVAVEADVS 65 Query: 337 NHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKE 516 + R+ E + GG+DIL + DE+ WD++ VN+K +L A+ Sbjct: 66 SRRSVERMAERVAGELGGIDILVNNAAIYPLRPWT-EIDEEEWDRVLAVNIKGYFLCARA 124 Query: 517 AYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVA 696 AYP + +RGGG I+ ++SI + Y SK ++G T+ +A E E I VN V+ Sbjct: 125 AYPYMRERGGGRIINVASITFFIGWAGFLDYVSSKGAVVGFTRTLAREVGPEGITVNAVS 184 >UniRef50_A5MZ18 Cluster: FabG2; n=2; Clostridia|Rep: FabG2 - Clostridium kluyveri DSM 555 Length = 250 Score = 88.6 bits (210), Expect = 1e-16 Identities = 52/187 (27%), Positives = 91/187 (48%), Gaps = 4/187 (2%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVI----CSRKESNVGKAVQSLRSEGITVE 315 + KVAIVT ++ GIG AIA + EGA +++ +K V K ++ ++ I V+ Sbjct: 2 KLKDKVAIVTGASRGIGKAIAIEMAKEGARIIVNYNNSKKKALEVVKEIEDIKGTSIAVK 61 Query: 316 GVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKS 495 V+ +++ ++A FG + IL TD++ WDK+F VN+K Sbjct: 62 A---DVSKRNEVKKMIDIAVENFGEIHILVNNAGILQQKPFESITDDE-WDKMFQVNMKG 117 Query: 496 SWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHEN 675 +++ +E P ++K G I+ ISSI Y +K ++ L +++A + Sbjct: 118 AFICTQECIPYMLKNNFGRIINISSIGGQWGGNLAVHYSATKAGIISLARSLARIYSKDG 177 Query: 676 IRVNCVA 696 I NC+A Sbjct: 178 INTNCIA 184 >UniRef50_A1UPQ1 Cluster: Short-chain dehydrogenase/reductase SDR; n=12; Mycobacterium|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium sp. (strain KMS) Length = 275 Score = 88.6 bits (210), Expect = 1e-16 Identities = 60/179 (33%), Positives = 86/179 (48%) Frame = +1 Query: 160 KVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVAN 339 +VAIVTA+ GIG AIA R EG V+ + AV L G V GV V Sbjct: 22 RVAIVTAAAAGIGKAIALRWCREGGCCVMADTDGEGLDAAVHELAESGAAVCGVAGDVCL 81 Query: 340 HEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKEA 519 + + E A ++FG +D L + + E+ W D+N+ S + ++K Sbjct: 82 SDVANSVVERALTEFGRLDTLFNVVGGSLARN-VEEISEEQWRSQIDMNLGSVFQMSKPV 140 Query: 520 YPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVA 696 P L + GGGSIV ++S A AY SK ++ LTK +A + +NIRVN +A Sbjct: 141 IPLLRQGGGGSIVNVASTAGILAENRCSAYSASKGGVVLLTKNMALDFARDNIRVNAIA 199 >UniRef50_A0QV78 Cluster: Cyclopentanol dehydrogenase; n=2; Bacteria|Rep: Cyclopentanol dehydrogenase - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 355 Score = 88.6 bits (210), Expect = 1e-16 Identities = 59/182 (32%), Positives = 79/182 (43%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 R +GKVA++T G G A A+ GA V IC E K LR G+ + Sbjct: 98 RLAGKVALITGGARGQGEAEARLFAQHGAHVYICDVLEEEGEKLAAELRGSGLQADFRFL 157 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 V + E R + G +D+L + DT + WD+I VN K L Sbjct: 158 DVTDAEQWSRTVAHIDAGAGRLDVL-INNAGINVRHQLTDTTSEEWDRIVAVNTKGQMLG 216 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 + P + + G GSI+ I S A P+ AY SK + GLTKA A E IRVN Sbjct: 217 MQACAPLMKRSGNGSIINIGSTAGIM-GHPVAAYSASKWAVRGLTKAAAMELASSGIRVN 275 Query: 688 CV 693 + Sbjct: 276 AM 277 >UniRef50_Q56318 Cluster: Uncharacterized oxidoreductase TM_0019; n=11; cellular organisms|Rep: Uncharacterized oxidoreductase TM_0019 - Thermotoga maritima Length = 256 Score = 88.6 bits (210), Expect = 1e-16 Identities = 54/176 (30%), Positives = 84/176 (47%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVA 336 GKVA+VT +GIG AIA+ G VVI E + + LR G+ V V VA Sbjct: 4 GKVAVVTGGGQGIGAAIAQLFAENGMKVVIAEIDEEAGVEREEMLRERGLDVTFVKTDVA 63 Query: 337 NHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKE 516 + + + +GGVD+L I + + W+++ VN+ ++ ++ Sbjct: 64 DENSVKNMVRKTVEIYGGVDVL-VNNAAVMSVKSIFERPLEEWERVIRVNLTGPYICSRY 122 Query: 517 AYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRV 684 E++KRGGG I+ I+S A+Q Y SK L+ LT ++A +IRV Sbjct: 123 CAEEMIKRGGGVIINIASTRAFQSEPDTEPYSASKGGLVALTHSLAVSLSRYHIRV 178 >UniRef50_Q05528 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=93; Bacteria|Rep: 2-deoxy-D-gluconate 3-dehydrogenase - Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937)) Length = 253 Score = 88.6 bits (210), Expect = 1e-16 Identities = 51/188 (27%), Positives = 96/188 (51%), Gaps = 1/188 (0%) Frame = +1 Query: 136 IQSTRFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVE 315 + + GKVA++T G+G +A L G +V + E + ++ + + G Sbjct: 3 LNTFNLQGKVALITGCDTGLGQGMAVGLAEAGCDIVGVNIVEPK--ETIEKVTAVGRRFL 60 Query: 316 GVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKS 495 + +++ L E A ++FG VDIL I + E+ WD + ++N+KS Sbjct: 61 SLTADMSDISGHAALVEKAVAEFGKVDILVNNAGIIRREDAI-EFSEKNWDDVMNLNIKS 119 Query: 496 SWLLAKEAYPELVKRG-GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHE 672 + +++ + +K+G GG I+ I+S+ ++Q P+ +Y SK ++G+T+ +ANE Sbjct: 120 VFFMSQTVARQFIKQGHGGKIINIASMLSFQGGIPVPSYTASKKRVMGITRIVANEWAKH 179 Query: 673 NIRVNCVA 696 NI VN +A Sbjct: 180 NINVNAIA 187 >UniRef50_UPI000023E6B9 Cluster: hypothetical protein FG02829.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG02829.1 - Gibberella zeae PH-1 Length = 264 Score = 88.2 bits (209), Expect = 2e-16 Identities = 57/199 (28%), Positives = 93/199 (46%), Gaps = 2/199 (1%) Frame = +1 Query: 106 ISTSANPVRAIQSTRFS--GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKA 279 ++ SA V + S+ FS GKVA++T + GIG +A LG G +V+ +R+ + Sbjct: 1 MAPSAQAVSSYLSSLFSLAGKVAVITGGSSGIGREMAIALGRAGCRIVLIARRPKPLQDT 60 Query: 280 VQSLRSEGITVEGVVCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQ 459 + L +T E +V + N R + + G DIL + D + Sbjct: 61 IDHLADLHVTAEAIVADLGNPASVRDAIQAIKATVGSPDILINAAAVNYRPH-MNDLSQG 119 Query: 460 VWDKIFDVNVKSSWLLAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGL 639 WD+ VN+ + + L + P++ + G G I+ I S A++ GAYG SK LLGL Sbjct: 120 AWDETIAVNLTAPFALGQAFGPKMAENGWGRIINIISQQAFRCYGNSGAYGASKAGLLGL 179 Query: 640 TKAIANETVHENIRVNCVA 696 T++ A + N +A Sbjct: 180 TRSQAEAWSRHGVLCNAIA 198 >UniRef50_Q929J7 Cluster: Lin2278 protein; n=14; Bacteria|Rep: Lin2278 protein - Listeria innocua Length = 253 Score = 88.2 bits (209), Expect = 2e-16 Identities = 52/183 (28%), Positives = 83/183 (45%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 + +GKVA+VT + G+G IA EGA VV+ K V + E T VV Sbjct: 3 KLAGKVAVVTGAASGMGQQIAVLFAKEGAKVVVADLNLEAAQKTVALIEDEQGTALAVVA 62 Query: 328 HVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLL 507 +V + + AT +G +DIL + +++WDK+F +N Sbjct: 63 NVTKQDDIESMINKATETYGTLDILVNNAGIMDNFVPAGELTDELWDKVFAINTTGVMRA 122 Query: 508 AKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVN 687 ++A ++G G IV I+S + AY SK ++G TK + + ++NIR N Sbjct: 123 TRKALHIFEEKGQGVIVNIASAGGLFGSRAGAAYTASKHAVVGFTKNVGFQYANKNIRCN 182 Query: 688 CVA 696 +A Sbjct: 183 AIA 185 >UniRef50_Q8U9R1 Cluster: Short-chain dehydrogenase; n=3; Rhizobium/Agrobacterium group|Rep: Short-chain dehydrogenase - Agrobacterium tumefaciens (strain C58 / ATCC 33970) Length = 248 Score = 88.2 bits (209), Expect = 2e-16 Identities = 56/183 (30%), Positives = 84/183 (45%), Gaps = 1/183 (0%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVC 327 R GKVAIVT + GIG A AK L +EGA V + S +NV V + + G T G+ Sbjct: 3 RLEGKVAIVTGAGRGIGRATAKLLATEGAKVAVLSLTPANVDAVVADIEAAGGTALGIAI 62 Query: 328 HVANHEHRRRLFEVATSKFGGVDIL-XXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWL 504 V++ + + + + +GG+DIL +LD + + FD + Sbjct: 63 DVSDADAIKPAIDTVVATWGGIDILVNNAFDPSVVQSSVLDLSVEQLQRNFDTGPIAFLR 122 Query: 505 LAKEAYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRV 684 + + AYP L G G I+ S+A P Y ++K + LT+ A E + I V Sbjct: 123 MMQAAYPHLKTSGEGRIINFGSMAGVTGMVPYAPYNMAKEAIRALTRVAAREWGADKITV 182 Query: 685 NCV 693 N V Sbjct: 183 NNV 185 >UniRef50_Q7WM80 Cluster: Probable short chain dehydrogenase; n=1; Bordetella bronchiseptica|Rep: Probable short chain dehydrogenase - Bordetella bronchiseptica (Alcaligenes bronchisepticus) Length = 259 Score = 88.2 bits (209), Expect = 2e-16 Identities = 49/180 (27%), Positives = 85/180 (47%) Frame = +1 Query: 157 GKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGITVEGVVCHVA 336 G+ +VT G+G +A G GA V++ +++ +AV+ LR++GI G V V+ Sbjct: 14 GRTVLVTGGASGLGLCMAATAGQAGARVIVNDVRDAACNEAVEGLRAQGIDARGAVFDVS 73 Query: 337 NHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSWLLAKE 516 + + D+L +++ D VW IFDV+V ++ A+ Sbjct: 74 SAAAVSDAVAALAAARWSPDVLVSNAGNQNRAP-VVEQDPAVWQSIFDVHVNGAFHCARA 132 Query: 517 AYPELVKRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETVHENIRVNCVA 696 P ++ +GGG I+ SS+AA + AY +K L T+A+A E + + N +A Sbjct: 133 VLPGMISQGGGRIIITSSVAALACMPGIAAYSAAKGALAAFTRALAVEYGGQGVTCNALA 192 >UniRef50_Q5KZB7 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=2; Geobacillus|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Geobacillus kaustophilus Length = 256 Score = 88.2 bits (209), Expect = 2e-16 Identities = 56/190 (29%), Positives = 95/190 (50%), Gaps = 7/190 (3%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVICSRKESNVGKAVQSLRSEGI--TVEGV 321 RF+ VA++T GIG A A RL EGA+VV+ R + + VQ + G+ + Sbjct: 2 RFANTVAVITGGGSGIGRATAVRLAQEGATVVLVGRTAVKLEETVQDITRLGVPGVADRF 61 Query: 322 VCHVANHEHRRRLFEVATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDKIFDVNVKSSW 501 V +HE R L +++G + +L L+ EQ WD + VN+KS + Sbjct: 62 AADVTDHEQVRALAAYVQNRYGDLHVLVNNAGISTHTKW-LELTEQEWDDVQRVNMKSVF 120 Query: 502 LLAKEAYPELV-----KRGGGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKAIANETV 666 L+++ P ++ +R +IV ++S++ +Q + Y +K ++ LTK++A E Sbjct: 121 LVSQTLAPLMIEGAKRERANRAIVNVASLSGHQAGAEIPHYSAAKAGVINLTKSLALELA 180 Query: 667 HENIRVNCVA 696 IRVN V+ Sbjct: 181 PYGIRVNSVS 190 >UniRef50_Q3WK27 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Actinomycetales|Rep: Short-chain dehydrogenase/reductase SDR - Frankia sp. EAN1pec Length = 280 Score = 88.2 bits (209), Expect = 2e-16 Identities = 64/196 (32%), Positives = 93/196 (47%), Gaps = 13/196 (6%) Frame = +1 Query: 148 RFSGKVAIVTASTEGIGYAIAKRLGSEGASVVIC--SRKESNVGKAVQS---LRSEGITV 312 + SGKVA++T + G G + A L EGA +V +R+ +V + + LR V Sbjct: 6 QLSGKVALITGAARGQGRSHAMLLAQEGADIVAVDIARQIDSVRYPLATEDELRETAEAV 65 Query: 313 EG----VVCHVANHEHRRRLFEV---ATSKFGGVDILXXXXXXXXXXXXILDTDEQVWDK 471 G V+C VA+ +L V A +FG +DIL + + +Q W Sbjct: 66 SGLGRQVMCKVADVRSSEQLSAVVDKAMERFGHIDILCVNAGIAQFAKAVWELTDQEWRD 125 Query: 472 IFDVNVKSSWLLAKEAYPELVKRG-GGSIVFISSIAAYQPTEPLGAYGVSKTTLLGLTKA 648 I DVN+ +W K P + G GGSI+ +S + +P LGAY SK L GL + Sbjct: 126 ILDVNLTGAWKTVKAVAPAMTGTGRGGSIIVTASSTSLKPRPNLGAYNTSKHGLTGLVGS 185 Query: 649 IANETVHENIRVNCVA 696 +A E IRVN +A Sbjct: 186 LAIELAPAGIRVNAIA 201 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.317 0.132 0.376 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 718,230,826 Number of Sequences: 1657284 Number of extensions: 14759946 Number of successful extensions: 49580 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 45683 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 47566 length of database: 575,637,011 effective HSP length: 98 effective length of database: 413,223,179 effective search space used: 55371905986 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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