Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP27_F_N21
(860 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC026179-1|AAH26179.1| 418|Homo sapiens SEC61A2 protein protein. 248 3e-65
AF346603-1|AAK29084.1| 476|Homo sapiens Sec61 alpha form 2 prot... 248 3e-65
AK022640-1|BAB14148.1| 437|Homo sapiens protein ( Homo sapiens ... 245 2e-64
AF346602-1|AAK29083.1| 476|Homo sapiens Sec61 alpha form 1 prot... 243 6e-64
AF084458-1|AAD39847.1| 476|Homo sapiens sec61 homolog protein. 243 6e-64
AK074928-1|BAC11298.1| 356|Homo sapiens protein ( Homo sapiens ... 97 1e-19
AK127681-1|BAC87083.1| 126|Homo sapiens protein ( Homo sapiens ... 32 3.1
BC012885-1|AAH12885.1| 480|Homo sapiens PLXDC2 protein protein. 30 9.4
AY358486-1|AAQ88850.1| 529|Homo sapiens ARFP2514 protein. 30 9.4
AL353147-3|CAH71084.1| 480|Homo sapiens plexin domain containin... 30 9.4
AL353147-2|CAH71083.1| 529|Homo sapiens plexin domain containin... 30 9.4
AK127356-1|BAC86941.1| 170|Homo sapiens protein ( Homo sapiens ... 30 9.4
AF378757-1|AAL11994.1| 529|Homo sapiens tumor endothelial marke... 30 9.4
>BC026179-1|AAH26179.1| 418|Homo sapiens SEC61A2 protein protein.
Length = 418
Score = 248 bits (606), Expect = 3e-65
Identities = 117/121 (96%), Positives = 120/121 (99%)
Frame = +1
Query: 193 MGIKFLEVIKPFCSILPEIAKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 372
MGIKFLEVIKPFC++LPEI KPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD
Sbjct: 1 MGIKFLEVIKPFCAVLPEIQKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 60
Query: 373 PFYWIRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 552
PFYW+RVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG
Sbjct: 61 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 120
Query: 553 M 555
M
Sbjct: 121 M 121
Score = 101 bits (243), Expect = 3e-21
Identities = 54/85 (63%), Positives = 64/85 (75%), Gaps = 1/85 (1%)
Frame = +3
Query: 609 NPVKLVPEVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSWYPSG*LLQTSV-KPLXGKAF 785
+P ++ +CLLIIIQLFVAGLIVLLLDELLQKGYGLGS + T++ + + KAF
Sbjct: 139 DPAEMGAGICLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISL--FIATNICETIVWKAF 196
Query: 786 SPATVNTGRGTXFXGAVIXWFHLLA 860
SP T+NTGRGT F GAVI FHLLA
Sbjct: 197 SPTTINTGRGTEFEGAVIALFHLLA 221
Score = 58.4 bits (135), Expect = 3e-08
Identities = 33/74 (44%), Positives = 45/74 (60%)
Frame = +2
Query: 557 VITVGXAIVYVMTGMYGEPSEIGARSVPPHYHTTVCGRSYCVVAR*IAPERIWIGVLVSL 736
+IT+G AIVYVMTGMYG+P+E+GA ++ + + +G +SL
Sbjct: 122 IITIGQAIVYVMTGMYGDPAEMGAGICLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISL 181
Query: 737 WLIATNICETIVWK 778
+ IATNICETIVWK
Sbjct: 182 F-IATNICETIVWK 194
>AF346603-1|AAK29084.1| 476|Homo sapiens Sec61 alpha form 2
protein.
Length = 476
Score = 248 bits (606), Expect = 3e-65
Identities = 117/121 (96%), Positives = 120/121 (99%)
Frame = +1
Query: 193 MGIKFLEVIKPFCSILPEIAKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 372
MGIKFLEVIKPFC++LPEI KPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD
Sbjct: 1 MGIKFLEVIKPFCAVLPEIQKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 60
Query: 373 PFYWIRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 552
PFYW+RVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG
Sbjct: 61 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 120
Query: 553 M 555
M
Sbjct: 121 M 121
Score = 101 bits (243), Expect = 3e-21
Identities = 54/85 (63%), Positives = 64/85 (75%), Gaps = 1/85 (1%)
Frame = +3
Query: 609 NPVKLVPEVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSWYPSG*LLQTSV-KPLXGKAF 785
+P ++ +CLLIIIQLFVAGLIVLLLDELLQKGYGLGS + T++ + + KAF
Sbjct: 139 DPAEMGAGICLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISL--FIATNICETIVWKAF 196
Query: 786 SPATVNTGRGTXFXGAVIXWFHLLA 860
SP T+NTGRGT F GAVI FHLLA
Sbjct: 197 SPTTINTGRGTEFEGAVIALFHLLA 221
Score = 58.4 bits (135), Expect = 3e-08
Identities = 33/74 (44%), Positives = 45/74 (60%)
Frame = +2
Query: 557 VITVGXAIVYVMTGMYGEPSEIGARSVPPHYHTTVCGRSYCVVAR*IAPERIWIGVLVSL 736
+IT+G AIVYVMTGMYG+P+E+GA ++ + + +G +SL
Sbjct: 122 IITIGQAIVYVMTGMYGDPAEMGAGICLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISL 181
Query: 737 WLIATNICETIVWK 778
+ IATNICETIVWK
Sbjct: 182 F-IATNICETIVWK 194
>AK022640-1|BAB14148.1| 437|Homo sapiens protein ( Homo sapiens
cDNA FLJ12578 fis, clone NT2RM4001054, moderately
similar to Homo sapiens sec61 homolog mRNA. ).
Length = 437
Score = 245 bits (599), Expect = 2e-64
Identities = 116/121 (95%), Positives = 119/121 (98%)
Frame = +1
Query: 193 MGIKFLEVIKPFCSILPEIAKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 372
MGIKFLEVIKPFC++ PEI KPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD
Sbjct: 1 MGIKFLEVIKPFCAVPPEIQKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 60
Query: 373 PFYWIRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 552
PFYW+RVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG
Sbjct: 61 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 120
Query: 553 M 555
M
Sbjct: 121 M 121
Score = 101 bits (243), Expect = 3e-21
Identities = 54/85 (63%), Positives = 64/85 (75%), Gaps = 1/85 (1%)
Frame = +3
Query: 609 NPVKLVPEVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSWYPSG*LLQTSV-KPLXGKAF 785
+P ++ +CLLIIIQLFVAGLIVLLLDELLQKGYGLGS + T++ + + KAF
Sbjct: 139 DPAEMGAGICLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISL--FIATNICETIVWKAF 196
Query: 786 SPATVNTGRGTXFXGAVIXWFHLLA 860
SP T+NTGRGT F GAVI FHLLA
Sbjct: 197 SPTTINTGRGTEFEGAVIALFHLLA 221
Score = 56.8 bits (131), Expect = 9e-08
Identities = 32/74 (43%), Positives = 45/74 (60%)
Frame = +2
Query: 557 VITVGXAIVYVMTGMYGEPSEIGARSVPPHYHTTVCGRSYCVVAR*IAPERIWIGVLVSL 736
+IT+G AIVYV+TGMYG+P+E+GA ++ + + +G +SL
Sbjct: 122 IITIGQAIVYVITGMYGDPAEMGAGICLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISL 181
Query: 737 WLIATNICETIVWK 778
+ IATNICETIVWK
Sbjct: 182 F-IATNICETIVWK 194
>AF346602-1|AAK29083.1| 476|Homo sapiens Sec61 alpha form 1
protein.
Length = 476
Score = 243 bits (595), Expect = 6e-64
Identities = 116/121 (95%), Positives = 118/121 (97%)
Frame = +1
Query: 193 MGIKFLEVIKPFCSILPEIAKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 372
M IKFLEVIKPFC ILPEI KPERKIQF+EKVLWTAITLFIFLVCCQIPLFGIMSSDSAD
Sbjct: 1 MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 60
Query: 373 PFYWIRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 552
PFYW+RVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG
Sbjct: 61 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 120
Query: 553 M 555
M
Sbjct: 121 M 121
Score = 96.7 bits (230), Expect = 1e-19
Identities = 52/85 (61%), Positives = 62/85 (72%), Gaps = 1/85 (1%)
Frame = +3
Query: 609 NPVKLVPEVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSWYPSG*LLQTSV-KPLXGKAF 785
+P ++ +CLLI IQLFVAGLIVLLLDELLQKGYGLGS + T++ + + KAF
Sbjct: 139 DPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGISL--FIATNICETIVWKAF 196
Query: 786 SPATVNTGRGTXFXGAVIXWFHLLA 860
SP TVNTGRG F GA+I FHLLA
Sbjct: 197 SPTTVNTGRGMEFEGAIIALFHLLA 221
Score = 58.8 bits (136), Expect = 2e-08
Identities = 35/75 (46%), Positives = 48/75 (64%), Gaps = 1/75 (1%)
Frame = +2
Query: 557 VITVGXAIVYVMTGMYGEPSEIGAR-SVPPHYHTTVCGRSYCVVAR*IAPERIWIGVLVS 733
+IT+G +IVYVMTGMYG+PSE+GA + V G ++ + + +G +S
Sbjct: 122 IITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDE-LLQKGYGLGSGIS 180
Query: 734 LWLIATNICETIVWK 778
L+ IATNICETIVWK
Sbjct: 181 LF-IATNICETIVWK 194
>AF084458-1|AAD39847.1| 476|Homo sapiens sec61 homolog protein.
Length = 476
Score = 243 bits (595), Expect = 6e-64
Identities = 116/121 (95%), Positives = 118/121 (97%)
Frame = +1
Query: 193 MGIKFLEVIKPFCSILPEIAKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 372
M IKFLEVIKPFC ILPEI KPERKIQF+EKVLWTAITLFIFLVCCQIPLFGIMSSDSAD
Sbjct: 1 MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 60
Query: 373 PFYWIRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 552
PFYW+RVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG
Sbjct: 61 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 120
Query: 553 M 555
M
Sbjct: 121 M 121
Score = 96.7 bits (230), Expect = 1e-19
Identities = 52/85 (61%), Positives = 62/85 (72%), Gaps = 1/85 (1%)
Frame = +3
Query: 609 NPVKLVPEVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSWYPSG*LLQTSV-KPLXGKAF 785
+P ++ +CLLI IQLFVAGLIVLLLDELLQKGYGLGS + T++ + + KAF
Sbjct: 139 DPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGISL--FIATNICETIVWKAF 196
Query: 786 SPATVNTGRGTXFXGAVIXWFHLLA 860
SP TVNTGRG F GA+I FHLLA
Sbjct: 197 SPTTVNTGRGMEFEGAIIALFHLLA 221
Score = 58.8 bits (136), Expect = 2e-08
Identities = 35/75 (46%), Positives = 48/75 (64%), Gaps = 1/75 (1%)
Frame = +2
Query: 557 VITVGXAIVYVMTGMYGEPSEIGAR-SVPPHYHTTVCGRSYCVVAR*IAPERIWIGVLVS 733
+IT+G +IVYVMTGMYG+PSE+GA + V G ++ + + +G +S
Sbjct: 122 IITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDE-LLQKGYGLGSGIS 180
Query: 734 LWLIATNICETIVWK 778
L+ IATNICETIVWK
Sbjct: 181 LF-IATNICETIVWK 194
>AK074928-1|BAC11298.1| 356|Homo sapiens protein ( Homo sapiens
cDNA FLJ90447 fis, clone NT2RP3001240, highly similar to
Canis familiaris sec61 homologue mRNA. ).
Length = 356
Score = 96.7 bits (230), Expect = 1e-19
Identities = 52/85 (61%), Positives = 62/85 (72%), Gaps = 1/85 (1%)
Frame = +3
Query: 609 NPVKLVPEVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSWYPSG*LLQTSV-KPLXGKAF 785
+P ++ +CLLI IQLFVAGLIVLLLDELLQKGYGLGS + T++ + + KAF
Sbjct: 19 DPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGISL--FIATNICETIVWKAF 76
Query: 786 SPATVNTGRGTXFXGAVIXWFHLLA 860
SP TVNTGRG F GA+I FHLLA
Sbjct: 77 SPTTVNTGRGMEFEGAIIALFHLLA 101
Score = 58.8 bits (136), Expect = 2e-08
Identities = 35/75 (46%), Positives = 48/75 (64%), Gaps = 1/75 (1%)
Frame = +2
Query: 557 VITVGXAIVYVMTGMYGEPSEIGAR-SVPPHYHTTVCGRSYCVVAR*IAPERIWIGVLVS 733
+IT+G +IVYVMTGMYG+PSE+GA + V G ++ + + +G +S
Sbjct: 2 IITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDE-LLQKGYGLGSGIS 60
Query: 734 LWLIATNICETIVWK 778
L+ IATNICETIVWK
Sbjct: 61 LF-IATNICETIVWK 74
>AK127681-1|BAC87083.1| 126|Homo sapiens protein ( Homo sapiens
cDNA FLJ45779 fis, clone NETRP2005282. ).
Length = 126
Score = 31.9 bits (69), Expect = 3.1
Identities = 16/47 (34%), Positives = 22/47 (46%), Gaps = 5/47 (10%)
Frame = +1
Query: 565 CWSXYCLCNDWN-VWRTQ*NW----CPKCASSLSYNCLWPVLLCCCS 690
CWS +CL W + N+ P+ ++ NCLW LLC S
Sbjct: 77 CWSLHCLIEPWGFALQIHLNYKYQSSPESVLAVERNCLWVSLLCLFS 123
>BC012885-1|AAH12885.1| 480|Homo sapiens PLXDC2 protein protein.
Length = 480
Score = 30.3 bits (65), Expect = 9.4
Identities = 15/37 (40%), Positives = 17/37 (45%), Gaps = 1/37 (2%)
Frame = +1
Query: 613 Q*NWCPKCASS-LSYNCLWPVLLCCCSMNCSRKDMDW 720
Q N C C SS + +NC W L CS R DW
Sbjct: 281 QFNRCGPCVSSQIGFNCSWCSKLQRCSSGFDRHRQDW 317
>AY358486-1|AAQ88850.1| 529|Homo sapiens ARFP2514 protein.
Length = 529
Score = 30.3 bits (65), Expect = 9.4
Identities = 15/37 (40%), Positives = 17/37 (45%), Gaps = 1/37 (2%)
Frame = +1
Query: 613 Q*NWCPKCASS-LSYNCLWPVLLCCCSMNCSRKDMDW 720
Q N C C SS + +NC W L CS R DW
Sbjct: 330 QFNRCGPCVSSQIGFNCSWCSKLQRCSSGFDRHRQDW 366
>AL353147-3|CAH71084.1| 480|Homo sapiens plexin domain containing 2
protein.
Length = 480
Score = 30.3 bits (65), Expect = 9.4
Identities = 15/37 (40%), Positives = 17/37 (45%), Gaps = 1/37 (2%)
Frame = +1
Query: 613 Q*NWCPKCASS-LSYNCLWPVLLCCCSMNCSRKDMDW 720
Q N C C SS + +NC W L CS R DW
Sbjct: 281 QFNRCGPCVSSQIGFNCSWCSKLQRCSSGFDRHRQDW 317
>AL353147-2|CAH71083.1| 529|Homo sapiens plexin domain containing 2
protein.
Length = 529
Score = 30.3 bits (65), Expect = 9.4
Identities = 15/37 (40%), Positives = 17/37 (45%), Gaps = 1/37 (2%)
Frame = +1
Query: 613 Q*NWCPKCASS-LSYNCLWPVLLCCCSMNCSRKDMDW 720
Q N C C SS + +NC W L CS R DW
Sbjct: 330 QFNRCGPCVSSQIGFNCSWCSKLQRCSSGFDRHRQDW 366
>AK127356-1|BAC86941.1| 170|Homo sapiens protein ( Homo sapiens
cDNA FLJ45430 fis, clone BRHIP3039430. ).
Length = 170
Score = 30.3 bits (65), Expect = 9.4
Identities = 13/37 (35%), Positives = 22/37 (59%), Gaps = 3/37 (8%)
Frame = -1
Query: 554 IPNNFCAPLNKALSFGVSPTSM---ILAPASNCMMSP 453
+P F AP+N + + G+SP ++ P + C+MSP
Sbjct: 52 VPYWFVAPINSSFTLGISPNAIPPPFPHPMTGCVMSP 88
>AF378757-1|AAL11994.1| 529|Homo sapiens tumor endothelial marker
7-related precursor protein.
Length = 529
Score = 30.3 bits (65), Expect = 9.4
Identities = 15/37 (40%), Positives = 17/37 (45%), Gaps = 1/37 (2%)
Frame = +1
Query: 613 Q*NWCPKCASS-LSYNCLWPVLLCCCSMNCSRKDMDW 720
Q N C C SS + +NC W L CS R DW
Sbjct: 330 QFNRCGPCVSSQIGFNCSWCSKLQRCSSGFDRHRQDW 366
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 127,383,098
Number of Sequences: 237096
Number of extensions: 2836258
Number of successful extensions: 5659
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 5419
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5640
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10984231046
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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