Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP25_F_E23
(890 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 90 9e-18
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 90 9e-18
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 90 9e-18
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 90 9e-18
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 90 9e-18
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 90 9e-18
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 90 9e-18
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 90 9e-18
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 90 9e-18
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 90 9e-18
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 90 9e-18
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 90 9e-18
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 89 3e-17
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 89 3e-17
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 89 3e-17
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 89 3e-17
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 89 3e-17
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 89 3e-17
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 89 3e-17
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 89 3e-17
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 89 3e-17
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 89 3e-17
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 77 3e-17
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 77 3e-17
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 77 3e-17
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 88 5e-17
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 87 6e-17
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 87 6e-17
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 87 8e-17
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 87 8e-17
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 87 8e-17
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 87 8e-17
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 87 8e-17
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 87 8e-17
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 87 8e-17
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 87 8e-17
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 85 2e-16
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 85 2e-16
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 85 2e-16
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 85 2e-16
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 85 2e-16
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 85 2e-16
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 85 2e-16
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 85 2e-16
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 85 2e-16
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 85 2e-16
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 85 2e-16
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 85 2e-16
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 85 2e-16
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 85 3e-16
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 83 1e-15
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 83 1e-15
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 83 1e-15
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 83 1e-15
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 83 2e-15
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 83 2e-15
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 83 2e-15
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 83 2e-15
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 83 2e-15
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 83 2e-15
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 83 2e-15
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 83 2e-15
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 83 2e-15
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 82 3e-15
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 82 3e-15
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 81 4e-15
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 81 4e-15
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 81 4e-15
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 81 4e-15
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 81 4e-15
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 81 4e-15
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 81 4e-15
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 81 4e-15
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 81 5e-15
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 81 5e-15
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 81 5e-15
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 81 5e-15
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 81 5e-15
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 80 1e-14
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 78 4e-14
AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens ... 74 8e-13
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 56 6e-11
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 56 6e-11
BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 49 3e-05
BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 49 3e-05
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 49 3e-05
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 49 3e-05
AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 49 3e-05
AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 47 8e-05
AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto red... 46 2e-04
AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthas... 46 2e-04
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 38 0.049
BC054001-1|AAH54001.1| 438|Homo sapiens OLFML2A protein protein. 36 0.20
AY358185-1|AAQ88552.1| 613|Homo sapiens olfactomedin-like protein. 36 0.20
AL354928-5|CAI39636.2| 438|Homo sapiens olfactomedin-like 2A pr... 36 0.20
AL354928-4|CAI39635.2| 652|Homo sapiens olfactomedin-like 2A pr... 36 0.20
AL354928-3|CAI39634.1| 318|Homo sapiens olfactomedin-like 2A pr... 36 0.20
AK074709-1|BAC11152.1| 353|Homo sapiens protein ( Homo sapiens ... 36 0.20
AB119055-1|BAD38864.1| 652|Homo sapiens photomedin-1 protein. 36 0.20
BC029488-1|AAH29488.1| 294|Homo sapiens sperm acrosome associat... 31 5.6
AL136096-1|CAI19915.1| 294|Homo sapiens sperm acrosome associat... 31 5.6
AF203447-1|AAG31422.1| 294|Homo sapiens sperm acrosome membrane... 31 5.6
AK092420-1|BAC03884.1| 357|Homo sapiens protein ( Homo sapiens ... 30 9.8
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 90.2 bits (214), Expect = 9e-18
Identities = 51/119 (42%), Positives = 72/119 (60%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKS 600
L NL L+YVDLYLIH+P+++ EN +L D VD TW + K GL KS
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKS 162
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN+ Q++ I++ GL+ KP Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 46.0 bits (104), Expect = 2e-04
Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 39.1 bits (87), Expect = 0.021
Identities = 20/40 (50%), Positives = 26/40 (65%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW + H E V PAL +SL Q
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQ 107
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 90.2 bits (214), Expect = 9e-18
Identities = 51/119 (42%), Positives = 72/119 (60%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKS 600
L NL L+YVDLYLIH+P+++ EN +L D VD TW + K GL KS
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKS 162
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN+ Q++ I++ GL+ KP Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 46.0 bits (104), Expect = 2e-04
Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 39.1 bits (87), Expect = 0.021
Identities = 20/40 (50%), Positives = 26/40 (65%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW + H E V PAL +SL Q
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQ 107
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 90.2 bits (214), Expect = 9e-18
Identities = 51/119 (42%), Positives = 72/119 (60%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKS 600
L NL L+YVDLYLIH+P+++ EN +L D VD TW + K GL KS
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKS 162
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN+ Q++ I++ GL+ KP Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 46.0 bits (104), Expect = 2e-04
Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 39.1 bits (87), Expect = 0.021
Identities = 20/40 (50%), Positives = 26/40 (65%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW + H E V PAL +SL Q
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQ 107
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 90.2 bits (214), Expect = 9e-18
Identities = 51/119 (42%), Positives = 72/119 (60%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKS 600
L NL L+YVDLYLIH+P+++ EN +L D VD TW + K GL KS
Sbjct: 86 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKS 145
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN+ Q++ I++ GL+ KP Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 146 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 204
Score = 39.5 bits (88), Expect = 0.016
Identities = 24/66 (36%), Positives = 36/66 (54%), Gaps = 1/66 (1%)
Frame = +2
Query: 179 VVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQEIL 355
V+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+QVG A+ +I
Sbjct: 1 VLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQVGLAIRSKIA 53
Query: 356 RRTKKR 373
+ KR
Sbjct: 54 DGSVKR 59
Score = 39.1 bits (87), Expect = 0.021
Identities = 20/40 (50%), Positives = 26/40 (65%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW + H E V PAL +SL Q
Sbjct: 51 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQ 90
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 90.2 bits (214), Expect = 9e-18
Identities = 51/119 (42%), Positives = 72/119 (60%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKS 600
L NL L+YVDLYLIH+P+++ EN +L D VD TW + K GL KS
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKS 162
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN+ Q++ I++ GL+ KP Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 46.0 bits (104), Expect = 2e-04
Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 39.1 bits (87), Expect = 0.021
Identities = 20/40 (50%), Positives = 26/40 (65%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW + H E V PAL +SL Q
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQ 107
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 90.2 bits (214), Expect = 9e-18
Identities = 51/119 (42%), Positives = 72/119 (60%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKS 600
L NL L+YVDLYLIH+P+++ EN +L D VD TW + K GL KS
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKS 162
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN+ Q++ I++ GL+ KP Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 46.0 bits (104), Expect = 2e-04
Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 39.1 bits (87), Expect = 0.021
Identities = 20/40 (50%), Positives = 26/40 (65%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW + H E V PAL +SL Q
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQ 107
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 90.2 bits (214), Expect = 9e-18
Identities = 51/119 (42%), Positives = 72/119 (60%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKS 600
L NL L+YVDLYLIH+P+++ EN +L D VD TW + K GL KS
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKS 162
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN+ Q++ I++ GL+ KP Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 46.0 bits (104), Expect = 2e-04
Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 39.1 bits (87), Expect = 0.021
Identities = 20/40 (50%), Positives = 26/40 (65%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW + H E V PAL +SL Q
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQ 107
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 90.2 bits (214), Expect = 9e-18
Identities = 51/119 (42%), Positives = 72/119 (60%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKS 600
L NL L+YVDLYLIH+P+++ EN +L D VD TW + K GL KS
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKS 162
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN+ Q++ I++ GL+ KP Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 46.0 bits (104), Expect = 2e-04
Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 39.1 bits (87), Expect = 0.021
Identities = 20/40 (50%), Positives = 26/40 (65%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW + H E V PAL +SL Q
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQ 107
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 90.2 bits (214), Expect = 9e-18
Identities = 51/119 (42%), Positives = 72/119 (60%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKS 600
L NL L+YVDLYLIH+P+++ EN +L D VD TW + K GL KS
Sbjct: 69 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKS 128
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN+ Q++ I++ GL+ KP Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 129 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 187
Score = 39.1 bits (87), Expect = 0.021
Identities = 20/40 (50%), Positives = 26/40 (65%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW + H E V PAL +SL Q
Sbjct: 34 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQ 73
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 90.2 bits (214), Expect = 9e-18
Identities = 51/119 (42%), Positives = 72/119 (60%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKS 600
L NL L+YVDLYLIH+P+++ EN +L D VD TW + K GL KS
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKS 162
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN+ Q++ I++ GL+ KP Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 46.0 bits (104), Expect = 2e-04
Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 39.1 bits (87), Expect = 0.021
Identities = 20/40 (50%), Positives = 26/40 (65%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW + H E V PAL +SL Q
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQ 107
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 90.2 bits (214), Expect = 9e-18
Identities = 51/119 (42%), Positives = 72/119 (60%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKS 600
L NL L+YVDLYLIH+P+++ EN +L D VD TW + K GL KS
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKS 162
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN+ Q++ I++ GL+ KP Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 46.0 bits (104), Expect = 2e-04
Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 39.1 bits (87), Expect = 0.021
Identities = 20/40 (50%), Positives = 26/40 (65%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW + H E V PAL +SL Q
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQ 107
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 90.2 bits (214), Expect = 9e-18
Identities = 51/119 (42%), Positives = 72/119 (60%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKS 600
L NL L+YVDLYLIH+P+++ EN +L D VD TW + K GL KS
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKS 162
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN+ Q++ I++ GL+ KP Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 46.0 bits (104), Expect = 2e-04
Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 39.1 bits (87), Expect = 0.021
Identities = 20/40 (50%), Positives = 26/40 (65%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW + H E V PAL +SL Q
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQ 107
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 88.6 bits (210), Expect = 3e-17
Identities = 51/119 (42%), Positives = 70/119 (58%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKS 600
L NL L+YVDLYLIH+P+++ EN +L D VD TW M K GL KS
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKS 162
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN ++ I++ GL+ KP Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 163 IGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 45.6 bits (103), Expect = 2e-04
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 40.7 bits (91), Expect = 0.007
Identities = 20/40 (50%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW++ H E V PAL +SL Q
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQ 107
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 88.6 bits (210), Expect = 3e-17
Identities = 51/119 (42%), Positives = 70/119 (58%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKS 600
L NL L+YVDLYLIH+P+++ EN +L D VD TW M K GL KS
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKS 162
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN ++ I++ GL+ KP Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 163 IGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 45.6 bits (103), Expect = 2e-04
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 40.7 bits (91), Expect = 0.007
Identities = 20/40 (50%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW++ H E V PAL +SL Q
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQ 107
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 88.6 bits (210), Expect = 3e-17
Identities = 51/119 (42%), Positives = 70/119 (58%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKS 600
L NL L+YVDLYLIH+P+++ EN +L D VD TW M K GL KS
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKS 162
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN ++ I++ GL+ KP Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 163 IGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 45.6 bits (103), Expect = 2e-04
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 40.7 bits (91), Expect = 0.007
Identities = 20/40 (50%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW++ H E V PAL +SL Q
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQ 107
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 88.6 bits (210), Expect = 3e-17
Identities = 51/119 (42%), Positives = 70/119 (58%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKS 600
L NL L+YVDLYLIH+P+++ EN +L D VD TW M K GL KS
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKS 162
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN ++ I++ GL+ KP Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 163 IGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 45.6 bits (103), Expect = 2e-04
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 40.7 bits (91), Expect = 0.007
Identities = 20/40 (50%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW++ H E V PAL +SL Q
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQ 107
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 88.6 bits (210), Expect = 3e-17
Identities = 51/119 (42%), Positives = 70/119 (58%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKS 600
L NL L+YVDLYLIH+P+++ EN +L D VD TW M K GL KS
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKS 162
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN ++ I++ GL+ KP Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 163 IGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 45.6 bits (103), Expect = 2e-04
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 40.7 bits (91), Expect = 0.007
Identities = 20/40 (50%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW++ H E V PAL +SL Q
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQ 107
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 88.6 bits (210), Expect = 3e-17
Identities = 51/119 (42%), Positives = 70/119 (58%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKS 600
L NL L+YVDLYLIH+P+++ EN +L D VD TW M K GL KS
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKS 162
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN ++ I++ GL+ KP Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 163 IGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 45.6 bits (103), Expect = 2e-04
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 40.7 bits (91), Expect = 0.007
Identities = 20/40 (50%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW++ H E V PAL +SL Q
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQ 107
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 88.6 bits (210), Expect = 3e-17
Identities = 51/119 (42%), Positives = 70/119 (58%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKS 600
L NL L+YVDLYLIH+P+++ EN +L D VD TW M K GL KS
Sbjct: 116 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKS 175
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN ++ I++ GL+ KP Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 176 IGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 234
Score = 45.6 bits (103), Expect = 2e-04
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q
Sbjct: 21 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 73
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 74 VGLAIRSKIADGSVKR 89
Score = 40.7 bits (91), Expect = 0.007
Identities = 20/40 (50%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW++ H E V PAL +SL Q
Sbjct: 81 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQ 120
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 88.6 bits (210), Expect = 3e-17
Identities = 51/119 (42%), Positives = 70/119 (58%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKS 600
L NL L+YVDLYLIH+P+++ EN +L D VD TW M K GL KS
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKS 162
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN ++ I++ GL+ KP Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 163 IGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 45.6 bits (103), Expect = 2e-04
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 40.7 bits (91), Expect = 0.007
Identities = 20/40 (50%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW++ H E V PAL +SL Q
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQ 107
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 88.6 bits (210), Expect = 3e-17
Identities = 51/119 (42%), Positives = 70/119 (58%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKS 600
L NL L+YVDLYLIH+P+++ EN +L D VD TW M K GL KS
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKS 162
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN ++ I++ GL+ KP Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 163 IGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 45.6 bits (103), Expect = 2e-04
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 40.7 bits (91), Expect = 0.007
Identities = 20/40 (50%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW++ H E V PAL +SL Q
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQ 107
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 88.6 bits (210), Expect = 3e-17
Identities = 51/119 (42%), Positives = 70/119 (58%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKS 600
L NL L+YVDLYLIH+P+++ EN +L D VD TW M K GL KS
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKS 162
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN ++ I++ GL+ KP Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 163 IGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 45.6 bits (103), Expect = 2e-04
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 40.7 bits (91), Expect = 0.007
Identities = 20/40 (50%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW++ H E V PAL +SL Q
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQ 107
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 77.0 bits (181), Expect(2) = 3e-17
Identities = 39/86 (45%), Positives = 51/86 (59%), Gaps = 2/86 (2%)
Frame = +1
Query: 517 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIELN 690
N + + DFLDTW M D GL K+IG+SNFN EQ++R+++ GL KP QIE +
Sbjct: 139 NMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECH 198
Query: 691 LNLQQPELFKFCRENDIVVMAYTPFG 768
L Q L FC+ D+ V AY P G
Sbjct: 199 PYLTQKNLISFCQSRDVSVTAYRPLG 224
Score = 37.9 bits (84), Expect = 0.049
Identities = 26/73 (35%), Positives = 36/73 (49%)
Frame = +2
Query: 167 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQ 346
G+IP V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 347 EILRRTKKRIYLY 385
+I +R L+
Sbjct: 53 KIKEGAVRREDLF 65
Score = 36.7 bits (81), Expect = 0.11
Identities = 18/36 (50%), Positives = 24/36 (66%), Gaps = 1/36 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSL 452
K EG ++RE +FI TKLW + H++ V A RKSL
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSL 88
Score = 31.9 bits (69), Expect(2) = 3e-17
Identities = 12/18 (66%), Positives = 14/18 (77%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPI 504
L L L Y+DLYLIHWP+
Sbjct: 88 LKALKLNYLDLYLIHWPM 105
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 77.0 bits (181), Expect(2) = 3e-17
Identities = 39/86 (45%), Positives = 51/86 (59%), Gaps = 2/86 (2%)
Frame = +1
Query: 517 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIELN 690
N + + DFLDTW M D GL K+IG+SNFN EQ++R+++ GL KP QIE +
Sbjct: 139 NMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECH 198
Query: 691 LNLQQPELFKFCRENDIVVMAYTPFG 768
L Q L FC+ D+ V AY P G
Sbjct: 199 PYLTQKNLISFCQSRDVSVTAYRPLG 224
Score = 37.9 bits (84), Expect = 0.049
Identities = 26/73 (35%), Positives = 36/73 (49%)
Frame = +2
Query: 167 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQ 346
G+IP V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 347 EILRRTKKRIYLY 385
+I +R L+
Sbjct: 53 KIKEGAVRREDLF 65
Score = 36.7 bits (81), Expect = 0.11
Identities = 18/36 (50%), Positives = 24/36 (66%), Gaps = 1/36 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSL 452
K EG ++RE +FI TKLW + H++ V A RKSL
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSL 88
Score = 31.9 bits (69), Expect(2) = 3e-17
Identities = 12/18 (66%), Positives = 14/18 (77%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPI 504
L L L Y+DLYLIHWP+
Sbjct: 88 LKALKLNYLDLYLIHWPM 105
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 77.0 bits (181), Expect(2) = 3e-17
Identities = 39/86 (45%), Positives = 51/86 (59%), Gaps = 2/86 (2%)
Frame = +1
Query: 517 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIELN 690
N + + DFLDTW M D GL K+IG+SNFN EQ++R+++ GL KP QIE +
Sbjct: 139 NMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECH 198
Query: 691 LNLQQPELFKFCRENDIVVMAYTPFG 768
L Q L FC+ D+ V AY P G
Sbjct: 199 PYLTQKNLISFCQSRDVSVTAYRPLG 224
Score = 37.9 bits (84), Expect = 0.049
Identities = 26/73 (35%), Positives = 36/73 (49%)
Frame = +2
Query: 167 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQ 346
G+IP V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 347 EILRRTKKRIYLY 385
+I +R L+
Sbjct: 53 KIKEGAVRREDLF 65
Score = 36.7 bits (81), Expect = 0.11
Identities = 18/36 (50%), Positives = 24/36 (66%), Gaps = 1/36 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSL 452
K EG ++RE +FI TKLW + H++ V A RKSL
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSL 88
Score = 31.9 bits (69), Expect(2) = 3e-17
Identities = 12/18 (66%), Positives = 14/18 (77%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPI 504
L L L Y+DLYLIHWP+
Sbjct: 88 LKALKLNYLDLYLIHWPM 105
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 87.8 bits (208), Expect = 5e-17
Identities = 49/121 (40%), Positives = 71/121 (58%), Gaps = 12/121 (9%)
Frame = +1
Query: 445 SPLXNLNLEYVDLYLIHWPIAMFENDT----------LLDNVDFLDTWRGMIDAKKLGLT 594
S L L L+YVDLYL+H+P+A+ +T + D VD TW M K GL
Sbjct: 101 SSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLA 160
Query: 595 KSIGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 768
KSIG+SNFN Q++ I++ GL+ KP Q+E + L Q +L FC+ DIV++A++ G
Sbjct: 161 KSIGVSNFNYRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 220
Query: 769 S 771
+
Sbjct: 221 T 221
Score = 48.4 bits (110), Expect = 3e-05
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+Q
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 39.1 bits (87), Expect = 0.021
Identities = 19/40 (47%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW ++ + + V PAL SL K Q
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQ 107
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 87.4 bits (207), Expect = 6e-17
Identities = 51/119 (42%), Positives = 71/119 (59%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAM------FEND----TLLDNVDFLDTWRGMIDAKKLGLTKS 600
L +L L+Y+DLYLIHWPI F D + + + LDTW M + GL K+
Sbjct: 97 LSDLKLDYLDLYLIHWPIGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKA 156
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IGISNFN Q++ I++ GL+ KP+ QIE + L Q +L ++C+ IVV AY+P GS
Sbjct: 157 IGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGS 215
Score = 50.0 bits (114), Expect = 1e-05
Identities = 28/79 (35%), Positives = 46/79 (58%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 328
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 329 GRALXQEILRRTKKRIYLY 385
G A+ +++ + KR L+
Sbjct: 56 GVAIQEKLREQVVKREELF 74
Score = 35.5 bits (78), Expect = 0.26
Identities = 15/30 (50%), Positives = 22/30 (73%)
Frame = +3
Query: 363 LKRESIFITTKLWNSYHEREQVIPALRKSL 452
+KRE +FI +KLW +YHE+ V A +K+L
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTL 97
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 87.4 bits (207), Expect = 6e-17
Identities = 49/121 (40%), Positives = 71/121 (58%), Gaps = 12/121 (9%)
Frame = +1
Query: 445 SPLXNLNLEYVDLYLIHWPIAMFENDT----------LLDNVDFLDTWRGMIDAKKLGLT 594
S L L L+YVDLYL+H+P+A+ +T + D VD TW M K GL
Sbjct: 101 SSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLCATWEVMEKCKDAGLA 160
Query: 595 KSIGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 768
KSIG+SNFN Q++ I++ GL+ KP Q+E + L Q +L FC+ DIV++A++ G
Sbjct: 161 KSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 220
Query: 769 S 771
+
Sbjct: 221 T 221
Score = 48.4 bits (110), Expect = 3e-05
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+Q
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 39.1 bits (87), Expect = 0.021
Identities = 19/40 (47%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW ++ + + V PAL SL K Q
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQ 107
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 87.0 bits (206), Expect = 8e-17
Identities = 50/119 (42%), Positives = 70/119 (58%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKS 600
L NL L+YVDLYLIH+P+++ EN +L D VD TW M K GL KS
Sbjct: 103 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKS 162
Query: 601 IGISNFNQEQIQRII-DSGLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN ++ I+ + GL+ +P Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 163 IGVSNFNHRLLEMILNEPGLKYEPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 45.6 bits (103), Expect = 2e-04
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 40.7 bits (91), Expect = 0.007
Identities = 20/40 (50%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW++ H E V PAL +SL Q
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQ 107
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 87.0 bits (206), Expect = 8e-17
Identities = 51/123 (41%), Positives = 72/123 (58%), Gaps = 12/123 (9%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKS 600
L NL L+YVDLYLIH+P+++ EN +L D VD TW + K L KS
Sbjct: 100 LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAELAKS 159
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSL 774
IG+SNFN+ ++ I++ GL+ KP Q+E + Q +L FC+ DIV++AY+ GSL
Sbjct: 160 IGVSNFNRSTLEMILNKPGLQVKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSL 219
Query: 775 FPE 783
E
Sbjct: 220 REE 222
Score = 46.0 bits (104), Expect = 2e-04
Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 5 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 57
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 58 VGLAIRSKIADGSVKR 73
Score = 36.3 bits (80), Expect = 0.15
Identities = 19/40 (47%), Positives = 25/40 (62%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW + H E PAL +SL Q
Sbjct: 65 KIADGSVKREDIFYTSKLWCNSHRPELDRPALERSLKNLQ 104
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 87.0 bits (206), Expect = 8e-17
Identities = 49/121 (40%), Positives = 71/121 (58%), Gaps = 12/121 (9%)
Frame = +1
Query: 445 SPLXNLNLEYVDLYLIHWPIAMFENDT----------LLDNVDFLDTWRGMIDAKKLGLT 594
S L L L+YVDLYL+H+P+A+ +T + D VD TW M K GL
Sbjct: 101 SSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLA 160
Query: 595 KSIGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 768
KSIG+SNFN Q++ I++ GL+ KP Q+E + L Q +L FC+ DIV++A++ G
Sbjct: 161 KSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 220
Query: 769 S 771
+
Sbjct: 221 T 221
Score = 48.4 bits (110), Expect = 3e-05
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+Q
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 39.1 bits (87), Expect = 0.021
Identities = 19/40 (47%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW ++ + + V PAL SL K Q
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQ 107
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 87.0 bits (206), Expect = 8e-17
Identities = 49/121 (40%), Positives = 71/121 (58%), Gaps = 12/121 (9%)
Frame = +1
Query: 445 SPLXNLNLEYVDLYLIHWPIAMFENDT----------LLDNVDFLDTWRGMIDAKKLGLT 594
S L L L+YVDLYL+H+P+A+ +T + D VD TW M K GL
Sbjct: 86 SSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLA 145
Query: 595 KSIGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 768
KSIG+SNFN Q++ I++ GL+ KP Q+E + L Q +L FC+ DIV++A++ G
Sbjct: 146 KSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 205
Query: 769 S 771
+
Sbjct: 206 T 206
Score = 44.8 bits (101), Expect = 4e-04
Identities = 26/68 (38%), Positives = 39/68 (57%), Gaps = 1/68 (1%)
Frame = +2
Query: 173 IPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQE 349
+PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+QVG A+ +
Sbjct: 1 MPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQVGLAIRSK 53
Query: 350 ILRRTKKR 373
I + KR
Sbjct: 54 IADGSVKR 61
Score = 39.1 bits (87), Expect = 0.021
Identities = 19/40 (47%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW ++ + + V PAL SL K Q
Sbjct: 53 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQ 92
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 87.0 bits (206), Expect = 8e-17
Identities = 49/121 (40%), Positives = 71/121 (58%), Gaps = 12/121 (9%)
Frame = +1
Query: 445 SPLXNLNLEYVDLYLIHWPIAMFENDT----------LLDNVDFLDTWRGMIDAKKLGLT 594
S L L L+YVDLYL+H+P+A+ +T + D VD TW M K GL
Sbjct: 99 SSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLA 158
Query: 595 KSIGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 768
KSIG+SNFN Q++ I++ GL+ KP Q+E + L Q +L FC+ DIV++A++ G
Sbjct: 159 KSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 218
Query: 769 S 771
+
Sbjct: 219 T 219
Score = 48.4 bits (110), Expect = 3e-05
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+Q
Sbjct: 6 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 58
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 59 VGLAIRSKIADGSVKR 74
Score = 39.1 bits (87), Expect = 0.021
Identities = 19/40 (47%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW ++ + + V PAL SL K Q
Sbjct: 66 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQ 105
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 87.0 bits (206), Expect = 8e-17
Identities = 49/121 (40%), Positives = 71/121 (58%), Gaps = 12/121 (9%)
Frame = +1
Query: 445 SPLXNLNLEYVDLYLIHWPIAMFENDT----------LLDNVDFLDTWRGMIDAKKLGLT 594
S L L L+YVDLYL+H+P+A+ +T + D VD TW M K GL
Sbjct: 101 SSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLA 160
Query: 595 KSIGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 768
KSIG+SNFN Q++ I++ GL+ KP Q+E + L Q +L FC+ DIV++A++ G
Sbjct: 161 KSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 220
Query: 769 S 771
+
Sbjct: 221 T 221
Score = 48.4 bits (110), Expect = 3e-05
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+Q
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 39.1 bits (87), Expect = 0.021
Identities = 19/40 (47%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW ++ + + V PAL SL K Q
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQ 107
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 87.0 bits (206), Expect = 8e-17
Identities = 49/121 (40%), Positives = 71/121 (58%), Gaps = 12/121 (9%)
Frame = +1
Query: 445 SPLXNLNLEYVDLYLIHWPIAMFENDT----------LLDNVDFLDTWRGMIDAKKLGLT 594
S L L L+YVDLYL+H+P+A+ +T + D VD TW M K GL
Sbjct: 101 SSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLA 160
Query: 595 KSIGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 768
KSIG+SNFN Q++ I++ GL+ KP Q+E + L Q +L FC+ DIV++A++ G
Sbjct: 161 KSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 220
Query: 769 S 771
+
Sbjct: 221 T 221
Score = 48.4 bits (110), Expect = 3e-05
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+Q
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 39.1 bits (87), Expect = 0.021
Identities = 19/40 (47%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW ++ + + V PAL SL K Q
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQ 107
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 87.0 bits (206), Expect = 8e-17
Identities = 49/121 (40%), Positives = 71/121 (58%), Gaps = 12/121 (9%)
Frame = +1
Query: 445 SPLXNLNLEYVDLYLIHWPIAMFENDT----------LLDNVDFLDTWRGMIDAKKLGLT 594
S L L L+YVDLYL+H+P+A+ +T + D VD TW M K GL
Sbjct: 101 SSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLA 160
Query: 595 KSIGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 768
KSIG+SNFN Q++ I++ GL+ KP Q+E + L Q +L FC+ DIV++A++ G
Sbjct: 161 KSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 220
Query: 769 S 771
+
Sbjct: 221 T 221
Score = 48.4 bits (110), Expect = 3e-05
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+Q
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 39.1 bits (87), Expect = 0.021
Identities = 19/40 (47%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW ++ + + V PAL SL K Q
Sbjct: 68 KIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQ 107
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 85.4 bits (202), Expect = 2e-16
Identities = 50/119 (42%), Positives = 70/119 (58%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAM------FEND----TLLDNVDFLDTWRGMIDAKKLGLTKS 600
L +L L+Y+DLYLIHWP F D + + + LDTW M + GL K+
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKA 156
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IGISNFN Q++ I++ GL+ KP+ QIE + L Q +L ++C+ IVV AY+P GS
Sbjct: 157 IGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGS 215
Score = 50.0 bits (114), Expect = 1e-05
Identities = 28/79 (35%), Positives = 46/79 (58%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 328
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 329 GRALXQEILRRTKKRIYLY 385
G A+ +++ + KR L+
Sbjct: 56 GVAIQEKLREQVVKREELF 74
Score = 35.5 bits (78), Expect = 0.26
Identities = 15/30 (50%), Positives = 22/30 (73%)
Frame = +3
Query: 363 LKRESIFITTKLWNSYHEREQVIPALRKSL 452
+KRE +FI +KLW +YHE+ V A +K+L
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTL 97
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 85.4 bits (202), Expect = 2e-16
Identities = 50/119 (42%), Positives = 70/119 (58%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAM------FEND----TLLDNVDFLDTWRGMIDAKKLGLTKS 600
L +L L+Y+DLYLIHWP F D + + + LDTW M + GL K+
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKA 156
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IGISNFN Q++ I++ GL+ KP+ QIE + L Q +L ++C+ IVV AY+P GS
Sbjct: 157 IGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGS 215
Score = 50.0 bits (114), Expect = 1e-05
Identities = 28/79 (35%), Positives = 46/79 (58%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 328
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 329 GRALXQEILRRTKKRIYLY 385
G A+ +++ + KR L+
Sbjct: 56 GVAIQEKLREQVVKREELF 74
Score = 35.5 bits (78), Expect = 0.26
Identities = 15/30 (50%), Positives = 22/30 (73%)
Frame = +3
Query: 363 LKRESIFITTKLWNSYHEREQVIPALRKSL 452
+KRE +FI +KLW +YHE+ V A +K+L
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTL 97
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 85.4 bits (202), Expect = 2e-16
Identities = 50/119 (42%), Positives = 70/119 (58%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAM------FEND----TLLDNVDFLDTWRGMIDAKKLGLTKS 600
L +L L+Y+DLYLIHWP F D + + + LDTW M + GL K+
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKA 156
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IGISNFN Q++ I++ GL+ KP+ QIE + L Q +L ++C+ IVV AY+P GS
Sbjct: 157 IGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGS 215
Score = 50.0 bits (114), Expect = 1e-05
Identities = 28/79 (35%), Positives = 46/79 (58%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 328
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 329 GRALXQEILRRTKKRIYLY 385
G A+ +++ + KR L+
Sbjct: 56 GVAIQEKLREQVVKREELF 74
Score = 35.5 bits (78), Expect = 0.26
Identities = 15/30 (50%), Positives = 22/30 (73%)
Frame = +3
Query: 363 LKRESIFITTKLWNSYHEREQVIPALRKSL 452
+KRE +FI +KLW +YHE+ V A +K+L
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTL 97
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 85.4 bits (202), Expect = 2e-16
Identities = 49/119 (41%), Positives = 69/119 (57%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMF---------ENDTLL-DNVDFLDTWRGMIDAKKLGLTKS 600
L NL L+Y DLYLIH+P+++ EN +L D VD TW M K GL KS
Sbjct: 103 LKNLQLDYADLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKS 162
Query: 601 IGISNFNQEQIQRII-DSGLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN ++ I+ + GL+ +P Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 163 IGVSNFNHRLLEMILNEPGLKYEPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
Score = 47.2 bits (107), Expect = 8e-05
Identities = 29/76 (38%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ PK K ++ AV A+EAGY HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGYHHIDSAHVYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 40.7 bits (91), Expect = 0.007
Identities = 20/40 (50%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW++ H E V PAL +SL Q
Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQ 107
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 85.4 bits (202), Expect = 2e-16
Identities = 50/119 (42%), Positives = 70/119 (58%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAM------FEND----TLLDNVDFLDTWRGMIDAKKLGLTKS 600
L +L L+Y+DLYLIHWP F D + + + LDTW M + GL K+
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKA 156
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IGISNFN Q++ I++ GL+ KP+ QIE + L Q +L ++C+ IVV AY+P GS
Sbjct: 157 IGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGS 215
Score = 50.0 bits (114), Expect = 1e-05
Identities = 28/79 (35%), Positives = 46/79 (58%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 328
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 329 GRALXQEILRRTKKRIYLY 385
G A+ +++ + KR L+
Sbjct: 56 GVAIQEKLREQVVKREELF 74
Score = 35.5 bits (78), Expect = 0.26
Identities = 15/30 (50%), Positives = 22/30 (73%)
Frame = +3
Query: 363 LKRESIFITTKLWNSYHEREQVIPALRKSL 452
+KRE +FI +KLW +YHE+ V A +K+L
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTL 97
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 85.4 bits (202), Expect = 2e-16
Identities = 50/119 (42%), Positives = 70/119 (58%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAM------FEND----TLLDNVDFLDTWRGMIDAKKLGLTKS 600
L +L L+Y+DLYLIHWP F D + + + LDTW M + GL K+
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKA 156
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IGISNFN Q++ I++ GL+ KP+ QIE + L Q +L ++C+ IVV AY+P GS
Sbjct: 157 IGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGS 215
Score = 49.2 bits (112), Expect = 2e-05
Identities = 27/77 (35%), Positives = 45/77 (58%)
Frame = +2
Query: 155 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 334
L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++VG
Sbjct: 7 LNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEVGV 57
Query: 335 ALXQEILRRTKKRIYLY 385
A+ +++ + KR L+
Sbjct: 58 AIQEKLREQVVKREELF 74
Score = 35.5 bits (78), Expect = 0.26
Identities = 15/30 (50%), Positives = 22/30 (73%)
Frame = +3
Query: 363 LKRESIFITTKLWNSYHEREQVIPALRKSL 452
+KRE +FI +KLW +YHE+ V A +K+L
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTL 97
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 85.4 bits (202), Expect = 2e-16
Identities = 50/119 (42%), Positives = 70/119 (58%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAM------FEND----TLLDNVDFLDTWRGMIDAKKLGLTKS 600
L +L L+Y+DLYLIHWP F D + + + LDTW M + GL K+
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKA 156
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IGISNFN Q++ I++ GL+ KP+ QIE + L Q +L ++C+ IVV AY+P GS
Sbjct: 157 IGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGS 215
Score = 50.0 bits (114), Expect = 1e-05
Identities = 28/79 (35%), Positives = 46/79 (58%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 328
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 329 GRALXQEILRRTKKRIYLY 385
G A+ +++ + KR L+
Sbjct: 56 GVAIQEKLREQVVKREELF 74
Score = 35.5 bits (78), Expect = 0.26
Identities = 15/30 (50%), Positives = 22/30 (73%)
Frame = +3
Query: 363 LKRESIFITTKLWNSYHEREQVIPALRKSL 452
+KRE +FI +KLW +YHE+ V A +K+L
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTL 97
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 85.4 bits (202), Expect = 2e-16
Identities = 50/119 (42%), Positives = 70/119 (58%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAM------FEND----TLLDNVDFLDTWRGMIDAKKLGLTKS 600
L +L L+Y+DLYLIHWP F D + + + LDTW M + GL K+
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKA 156
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IGISNFN Q++ I++ GL+ KP+ QIE + L Q +L ++C+ IVV AY+P GS
Sbjct: 157 IGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGS 215
Score = 50.0 bits (114), Expect = 1e-05
Identities = 28/79 (35%), Positives = 46/79 (58%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 328
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 329 GRALXQEILRRTKKRIYLY 385
G A+ +++ + KR L+
Sbjct: 56 GVAIQEKLREQVVKREELF 74
Score = 35.5 bits (78), Expect = 0.26
Identities = 15/30 (50%), Positives = 22/30 (73%)
Frame = +3
Query: 363 LKRESIFITTKLWNSYHEREQVIPALRKSL 452
+KRE +FI +KLW +YHE+ V A +K+L
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTL 97
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 85.4 bits (202), Expect = 2e-16
Identities = 50/119 (42%), Positives = 70/119 (58%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAM------FEND----TLLDNVDFLDTWRGMIDAKKLGLTKS 600
L +L L+Y+DLYLIHWP F D + + + LDTW M + GL K+
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKA 156
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IGISNFN Q++ I++ GL+ KP+ QIE + L Q +L ++C+ IVV AY+P GS
Sbjct: 157 IGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGS 215
Score = 50.0 bits (114), Expect = 1e-05
Identities = 28/79 (35%), Positives = 46/79 (58%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 328
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 329 GRALXQEILRRTKKRIYLY 385
G A+ +++ + KR L+
Sbjct: 56 GVAIQEKLREQVVKREELF 74
Score = 35.5 bits (78), Expect = 0.26
Identities = 15/30 (50%), Positives = 22/30 (73%)
Frame = +3
Query: 363 LKRESIFITTKLWNSYHEREQVIPALRKSL 452
+KRE +FI +KLW +YHE+ V A +K+L
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTL 97
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 85.4 bits (202), Expect = 2e-16
Identities = 50/119 (42%), Positives = 70/119 (58%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAM------FEND----TLLDNVDFLDTWRGMIDAKKLGLTKS 600
L +L L+Y+DLYLIHWP F D + + + LDTW M + GL K+
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKA 156
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IGISNFN Q++ I++ GL+ KP+ QIE + L Q +L ++C+ IVV AY+P GS
Sbjct: 157 IGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGS 215
Score = 50.0 bits (114), Expect = 1e-05
Identities = 28/79 (35%), Positives = 46/79 (58%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 328
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 329 GRALXQEILRRTKKRIYLY 385
G A+ +++ + KR L+
Sbjct: 56 GVAIQEKLREQVVKREELF 74
Score = 35.5 bits (78), Expect = 0.26
Identities = 15/30 (50%), Positives = 22/30 (73%)
Frame = +3
Query: 363 LKRESIFITTKLWNSYHEREQVIPALRKSL 452
+KRE +FI +KLW +YHE+ V A +K+L
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTL 97
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 85.4 bits (202), Expect = 2e-16
Identities = 50/119 (42%), Positives = 70/119 (58%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAM------FEND----TLLDNVDFLDTWRGMIDAKKLGLTKS 600
L +L L+Y+DLYLIHWP F D + + + LDTW M + GL K+
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKA 156
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IGISNFN Q++ I++ GL+ KP+ QIE + L Q +L ++C+ IVV AY+P GS
Sbjct: 157 IGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGS 215
Score = 50.0 bits (114), Expect = 1e-05
Identities = 28/79 (35%), Positives = 46/79 (58%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 328
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 329 GRALXQEILRRTKKRIYLY 385
G A+ +++ + KR L+
Sbjct: 56 GVAIQEKLREQVVKREELF 74
Score = 35.5 bits (78), Expect = 0.26
Identities = 15/30 (50%), Positives = 22/30 (73%)
Frame = +3
Query: 363 LKRESIFITTKLWNSYHEREQVIPALRKSL 452
+KRE +FI +KLW +YHE+ V A +K+L
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTL 97
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 85.4 bits (202), Expect = 2e-16
Identities = 50/119 (42%), Positives = 70/119 (58%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAM------FEND----TLLDNVDFLDTWRGMIDAKKLGLTKS 600
L +L L+Y+DLYLIHWP F D + + + LDTW M + GL K+
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKA 156
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IGISNFN Q++ I++ GL+ KP+ QIE + L Q +L ++C+ IVV AY+P GS
Sbjct: 157 IGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGS 215
Score = 50.0 bits (114), Expect = 1e-05
Identities = 28/79 (35%), Positives = 46/79 (58%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 328
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 329 GRALXQEILRRTKKRIYLY 385
G A+ +++ + KR L+
Sbjct: 56 GVAIQEKLREQVVKREELF 74
Score = 35.5 bits (78), Expect = 0.26
Identities = 15/30 (50%), Positives = 22/30 (73%)
Frame = +3
Query: 363 LKRESIFITTKLWNSYHEREQVIPALRKSL 452
+KRE +FI +KLW +YHE+ V A +K+L
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTL 97
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 85.4 bits (202), Expect = 2e-16
Identities = 50/119 (42%), Positives = 70/119 (58%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAM------FEND----TLLDNVDFLDTWRGMIDAKKLGLTKS 600
L +L L+Y+DLYLIHWP F D + + + LDTW M + GL K+
Sbjct: 94 LSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKA 153
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IGISNFN Q++ I++ GL+ KP+ QIE + L Q +L ++C+ IVV AY+P GS
Sbjct: 154 IGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGS 212
Score = 50.0 bits (114), Expect = 1e-05
Identities = 28/79 (35%), Positives = 46/79 (58%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 328
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 2 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 52
Query: 329 GRALXQEILRRTKKRIYLY 385
G A+ +++ + KR L+
Sbjct: 53 GVAIQEKLREQVVKREELF 71
Score = 35.5 bits (78), Expect = 0.26
Identities = 15/30 (50%), Positives = 22/30 (73%)
Frame = +3
Query: 363 LKRESIFITTKLWNSYHEREQVIPALRKSL 452
+KRE +FI +KLW +YHE+ V A +K+L
Sbjct: 65 VKREELFIVSKLWCTYHEKGLVKGACQKTL 94
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 85.0 bits (201), Expect = 3e-16
Identities = 50/119 (42%), Positives = 69/119 (57%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAM------FEND----TLLDNVDFLDTWRGMIDAKKLGLTKS 600
L +L L+Y+DLYLIHWP F D + + + LDTW M + GL K+
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFRPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKA 156
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IGISNFN Q++ I+ GL+ KP+ QIE + L Q +L ++C+ IVV AY+P GS
Sbjct: 157 IGISNFNHLQVEMILSKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGS 215
Score = 50.0 bits (114), Expect = 1e-05
Identities = 28/79 (35%), Positives = 46/79 (58%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 328
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 329 GRALXQEILRRTKKRIYLY 385
G A+ +++ + KR L+
Sbjct: 56 GVAIQEKLREQVVKREELF 74
Score = 35.5 bits (78), Expect = 0.26
Identities = 15/30 (50%), Positives = 22/30 (73%)
Frame = +3
Query: 363 LKRESIFITTKLWNSYHEREQVIPALRKSL 452
+KRE +FI +KLW +YHE+ V A +K+L
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTL 97
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 83.4 bits (197), Expect = 1e-15
Identities = 47/116 (40%), Positives = 71/116 (61%), Gaps = 12/116 (10%)
Frame = +1
Query: 460 LNLEYVDLYLIHWPIAMFENDTLL---DNVDFL-------DTWRGMIDAKKLGLTKSIGI 609
L L+YVDLY+I P+A D + +N +L TW M K GL KS+G+
Sbjct: 109 LQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGV 168
Query: 610 SNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
SNFN+ Q++ I++ GL+ KP + Q+E + QP+L KFC+++DIV+ AY+P G+
Sbjct: 169 SNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGT 224
Score = 45.6 bits (103), Expect = 2e-04
Identities = 26/75 (34%), Positives = 40/75 (53%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 328
+ LS G +IP++ LGT+ + K T+ V A++ GY HID AY Y E +V
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATS-----VKVAIDTGYRHIDGAYIYQNEHEV 64
Query: 329 GRALXQEILRRTKKR 373
G A+ ++I +R
Sbjct: 65 GEAIREKIAEGKVRR 79
Score = 32.7 bits (71), Expect = 1.8
Identities = 16/37 (43%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
Frame = +3
Query: 345 KKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSL 452
+K +EG ++RE IF KLW + H E V P L ++L
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTL 106
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 83.4 bits (197), Expect = 1e-15
Identities = 47/116 (40%), Positives = 71/116 (61%), Gaps = 12/116 (10%)
Frame = +1
Query: 460 LNLEYVDLYLIHWPIAMFENDTLL---DNVDFL-------DTWRGMIDAKKLGLTKSIGI 609
L L+YVDLY+I P+A D + +N +L TW M K GL KS+G+
Sbjct: 109 LQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGV 168
Query: 610 SNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
SNFN+ Q++ I++ GL+ KP + Q+E + QP+L KFC+++DIV+ AY+P G+
Sbjct: 169 SNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGT 224
Score = 45.6 bits (103), Expect = 2e-04
Identities = 26/75 (34%), Positives = 40/75 (53%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 328
+ LS G +IP++ LGT+ + K T+ V A++ GY HID AY Y E +V
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATS-----VKVAIDTGYRHIDGAYIYQNEHEV 64
Query: 329 GRALXQEILRRTKKR 373
G A+ ++I +R
Sbjct: 65 GEAIREKIAEGKVRR 79
Score = 32.7 bits (71), Expect = 1.8
Identities = 16/37 (43%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
Frame = +3
Query: 345 KKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSL 452
+K +EG ++RE IF KLW + H E V P L ++L
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTL 106
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 83.4 bits (197), Expect = 1e-15
Identities = 47/116 (40%), Positives = 71/116 (61%), Gaps = 12/116 (10%)
Frame = +1
Query: 460 LNLEYVDLYLIHWPIAMFENDTLL---DNVDFL-------DTWRGMIDAKKLGLTKSIGI 609
L L+YVDLY+I P+A D + +N +L TW M K GL KS+G+
Sbjct: 109 LQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGV 168
Query: 610 SNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
SNFN+ Q++ I++ GL+ KP + Q+E + QP+L KFC+++DIV+ AY+P G+
Sbjct: 169 SNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGT 224
Score = 45.6 bits (103), Expect = 2e-04
Identities = 26/75 (34%), Positives = 40/75 (53%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 328
+ LS G +IP++ LGT+ + K T+ V A++ GY HID AY Y E +V
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATS-----VKVAIDTGYRHIDGAYIYQNEHEV 64
Query: 329 GRALXQEILRRTKKR 373
G A+ ++I +R
Sbjct: 65 GEAIREKIAEGKVRR 79
Score = 32.7 bits (71), Expect = 1.8
Identities = 16/37 (43%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
Frame = +3
Query: 345 KKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSL 452
+K +EG ++RE IF KLW + H E V P L ++L
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTL 106
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 83.4 bits (197), Expect = 1e-15
Identities = 47/116 (40%), Positives = 71/116 (61%), Gaps = 12/116 (10%)
Frame = +1
Query: 460 LNLEYVDLYLIHWPIAMFENDTLL---DNVDFL-------DTWRGMIDAKKLGLTKSIGI 609
L L+YVDLY+I P+A D + +N +L TW M K GL KS+G+
Sbjct: 109 LQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGV 168
Query: 610 SNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
SNFN+ Q++ I++ GL+ KP + Q+E + QP+L KFC+++DIV+ AY+P G+
Sbjct: 169 SNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGT 224
Score = 45.6 bits (103), Expect = 2e-04
Identities = 26/75 (34%), Positives = 40/75 (53%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 328
+ LS G +IP++ LGT+ + K T+ V A++ GY HID AY Y E +V
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATS-----VKVAIDTGYRHIDGAYIYQNEHEV 64
Query: 329 GRALXQEILRRTKKR 373
G A+ ++I +R
Sbjct: 65 GEAIREKIAEGKVRR 79
Score = 32.7 bits (71), Expect = 1.8
Identities = 16/37 (43%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
Frame = +3
Query: 345 KKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSL 452
+K +EG ++RE IF KLW + H E V P L ++L
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTL 106
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 82.6 bits (195), Expect = 2e-15
Identities = 47/119 (39%), Positives = 67/119 (56%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKS 600
L L+YVDLYLIH P+++ + L D VD TW M K GL KS
Sbjct: 105 LKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKS 164
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN+ Q++ I++ GL+ KP Q+E + + +L FC+ DIV++AY+ GS
Sbjct: 165 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGS 223
Score = 46.0 bits (104), Expect = 2e-04
Identities = 27/76 (35%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q
Sbjct: 10 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 62
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 63 VGLAIRSKIADGSVKR 78
Score = 45.2 bits (102), Expect = 3e-04
Identities = 21/40 (52%), Positives = 29/40 (72%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW+++H E V PAL SL K+Q
Sbjct: 70 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQ 109
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 82.6 bits (195), Expect = 2e-15
Identities = 47/119 (39%), Positives = 67/119 (56%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKS 600
L L+YVDLYLIH P+++ + L D VD TW M K GL KS
Sbjct: 103 LKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKS 162
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN+ Q++ I++ GL+ KP Q+E + + +L FC+ DIV++AY+ GS
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGS 221
Score = 45.6 bits (103), Expect = 2e-04
Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAVRSKIADGSVKR 76
Score = 42.3 bits (95), Expect = 0.002
Identities = 21/40 (52%), Positives = 28/40 (70%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW + H E V PAL +SL K+Q
Sbjct: 68 KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKKAQ 107
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 82.6 bits (195), Expect = 2e-15
Identities = 47/119 (39%), Positives = 67/119 (56%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKS 600
L L+YVDLYLIH P+++ + L D VD TW M K GL KS
Sbjct: 103 LKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKS 162
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN+ Q++ I++ GL+ KP Q+E + + +L FC+ DIV++AY+ GS
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGS 221
Score = 46.0 bits (104), Expect = 2e-04
Identities = 27/76 (35%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 45.2 bits (102), Expect = 3e-04
Identities = 21/40 (52%), Positives = 29/40 (72%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW+++H E V PAL SL K+Q
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQ 107
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 82.6 bits (195), Expect = 2e-15
Identities = 47/119 (39%), Positives = 67/119 (56%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKS 600
L L+YVDLYLIH P+++ + L D VD TW M K GL KS
Sbjct: 103 LKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKS 162
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN+ Q++ I++ GL+ KP Q+E + + +L FC+ DIV++AY+ GS
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGS 221
Score = 46.0 bits (104), Expect = 2e-04
Identities = 27/76 (35%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 45.2 bits (102), Expect = 3e-04
Identities = 21/40 (52%), Positives = 29/40 (72%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW+++H E V PAL SL K+Q
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQ 107
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 82.6 bits (195), Expect = 2e-15
Identities = 47/119 (39%), Positives = 67/119 (56%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKS 600
L L+YVDLYLIH P+++ + L D VD TW M K GL KS
Sbjct: 103 LKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKS 162
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN+ Q++ I++ GL+ KP Q+E + + +L FC+ DIV++AY+ GS
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGS 221
Score = 46.0 bits (104), Expect = 2e-04
Identities = 27/76 (35%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 45.2 bits (102), Expect = 3e-04
Identities = 21/40 (52%), Positives = 29/40 (72%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW+++H E V PAL SL K+Q
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQ 107
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 82.6 bits (195), Expect = 2e-15
Identities = 47/119 (39%), Positives = 67/119 (56%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKS 600
L L+YVDLYLIH P+++ + L D VD TW M K GL KS
Sbjct: 103 LKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKS 162
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN+ Q++ I++ GL+ KP Q+E + + +L FC+ DIV++AY+ GS
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGS 221
Score = 46.0 bits (104), Expect = 2e-04
Identities = 27/76 (35%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 45.2 bits (102), Expect = 3e-04
Identities = 21/40 (52%), Positives = 29/40 (72%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW+++H E V PAL SL K+Q
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQ 107
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 82.6 bits (195), Expect = 2e-15
Identities = 47/119 (39%), Positives = 67/119 (56%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKS 600
L L+YVDLYLIH P+++ + L D VD TW M K GL KS
Sbjct: 103 LKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKS 162
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN+ Q++ I++ GL+ KP Q+E + + +L FC+ DIV++AY+ GS
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGS 221
Score = 44.4 bits (100), Expect = 6e-04
Identities = 26/76 (34%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ P+ K ++V+ A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVSK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 43.2 bits (97), Expect = 0.001
Identities = 21/40 (52%), Positives = 28/40 (70%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW++ H E V PAL SL K+Q
Sbjct: 68 KIADGSVKREDIFYTSKLWSTSHRPELVRPALENSLKKAQ 107
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 82.6 bits (195), Expect = 2e-15
Identities = 47/119 (39%), Positives = 67/119 (56%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKS 600
L L+YVDLYLIH P+++ + L D VD TW M K GL KS
Sbjct: 103 LKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKS 162
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN+ Q++ I++ GL+ KP Q+E + + +L FC+ DIV++AY+ GS
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGS 221
Score = 46.0 bits (104), Expect = 2e-04
Identities = 27/76 (35%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 45.2 bits (102), Expect = 3e-04
Identities = 21/40 (52%), Positives = 29/40 (72%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW+++H E V PAL SL K+Q
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQ 107
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 82.6 bits (195), Expect = 2e-15
Identities = 47/119 (39%), Positives = 67/119 (56%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKS 600
L L+YVDLYLIH P+++ + L D VD TW M K GL KS
Sbjct: 103 LKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKS 162
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN+ Q++ I++ GL+ KP Q+E + + +L FC+ DIV++AY+ GS
Sbjct: 163 IGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGS 221
Score = 46.0 bits (104), Expect = 2e-04
Identities = 27/76 (35%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 326 VGRALXQEILRRTKKR 373
VG A+ +I + KR
Sbjct: 61 VGLAIRSKIADGSVKR 76
Score = 45.2 bits (102), Expect = 3e-04
Identities = 21/40 (52%), Positives = 29/40 (72%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G +KRE IF T+KLW+++H E V PAL SL K+Q
Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQ 107
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 81.8 bits (193), Expect = 3e-15
Identities = 47/119 (39%), Positives = 67/119 (56%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKS 600
L L+YVDLYLIH P+++ + L D VD TW M K GL KS
Sbjct: 103 LKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKS 162
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN+ Q++ I++ GL+ KP Q+E + + +L FC+ DIV++AY+ GS
Sbjct: 163 IGVSNFNRRQLEIILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGS 221
Score = 44.4 bits (100), Expect = 6e-04
Identities = 25/69 (36%), Positives = 41/69 (59%), Gaps = 1/69 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 326 VGRALXQEI 352
VG A+ +I
Sbjct: 61 VGLAIRSKI 69
Score = 43.6 bits (98), Expect = 0.001
Identities = 20/40 (50%), Positives = 29/40 (72%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G ++RE IF T+KLW+++H E V PAL SL K+Q
Sbjct: 68 KIADGSVEREDIFYTSKLWSTFHRPELVRPALENSLKKAQ 107
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 81.8 bits (193), Expect = 3e-15
Identities = 47/119 (39%), Positives = 67/119 (56%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKS 600
L L+YVDLYLIH P+++ + L D VD TW M K GL KS
Sbjct: 103 LKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKS 162
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IG+SNFN+ Q++ I++ GL+ KP Q+E + + +L FC+ DIV++AY+ GS
Sbjct: 163 IGVSNFNRRQLEIILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGS 221
Score = 44.4 bits (100), Expect = 6e-04
Identities = 25/69 (36%), Positives = 41/69 (59%), Gaps = 1/69 (1%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 326 VGRALXQEI 352
VG A+ +I
Sbjct: 61 VGLAIRSKI 69
Score = 42.7 bits (96), Expect = 0.002
Identities = 20/40 (50%), Positives = 28/40 (70%), Gaps = 1/40 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
K ++G + RE IF T+KLW+++H E V PAL SL K+Q
Sbjct: 68 KIADGSVMREDIFYTSKLWSTFHRPELVRPALENSLKKAQ 107
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 81.4 bits (192), Expect = 4e-15
Identities = 42/117 (35%), Positives = 62/117 (52%), Gaps = 10/117 (8%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMFENDT----------LLDNVDFLDTWRGMIDAKKLGLTKS 600
L +L LEY+DLYL+HWP A D D+ + +TW+ + GL ++
Sbjct: 99 LADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQA 158
Query: 601 IGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
+G+SNFN QI I+ +P+ LQ+E + L Q EL C+ + V AY+P GS
Sbjct: 159 LGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGS 215
Score = 47.2 bits (107), Expect = 8e-05
Identities = 27/66 (40%), Positives = 38/66 (57%)
Frame = +2
Query: 155 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 334
L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G
Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58
Query: 335 ALXQEI 352
AL +++
Sbjct: 59 ALKEDV 64
Score = 42.7 bits (96), Expect = 0.002
Identities = 18/36 (50%), Positives = 25/36 (69%)
Frame = +3
Query: 357 EGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
+ + RE +F+T+KLWN+ H E V PALRK+L Q
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQ 103
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 81.4 bits (192), Expect = 4e-15
Identities = 42/117 (35%), Positives = 62/117 (52%), Gaps = 10/117 (8%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMFENDT----------LLDNVDFLDTWRGMIDAKKLGLTKS 600
L +L LEY+DLYL+HWP A D D+ + +TW+ + GL ++
Sbjct: 99 LADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQA 158
Query: 601 IGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
+G+SNFN QI I+ +P+ LQ+E + L Q EL C+ + V AY+P GS
Sbjct: 159 LGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGS 215
Score = 47.2 bits (107), Expect = 8e-05
Identities = 27/66 (40%), Positives = 38/66 (57%)
Frame = +2
Query: 155 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 334
L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G
Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58
Query: 335 ALXQEI 352
AL +++
Sbjct: 59 ALKEDV 64
Score = 42.7 bits (96), Expect = 0.002
Identities = 18/36 (50%), Positives = 25/36 (69%)
Frame = +3
Query: 357 EGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
+ + RE +F+T+KLWN+ H E V PALRK+L Q
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQ 103
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 81.4 bits (192), Expect = 4e-15
Identities = 42/117 (35%), Positives = 62/117 (52%), Gaps = 10/117 (8%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMFENDT----------LLDNVDFLDTWRGMIDAKKLGLTKS 600
L +L LEY+DLYL+HWP A D D+ + +TW+ + GL ++
Sbjct: 99 LADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQA 158
Query: 601 IGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
+G+SNFN QI I+ +P+ LQ+E + L Q EL C+ + V AY+P GS
Sbjct: 159 LGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGS 215
Score = 47.2 bits (107), Expect = 8e-05
Identities = 27/66 (40%), Positives = 38/66 (57%)
Frame = +2
Query: 155 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 334
L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G
Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58
Query: 335 ALXQEI 352
AL +++
Sbjct: 59 ALKEDV 64
Score = 42.7 bits (96), Expect = 0.002
Identities = 18/36 (50%), Positives = 25/36 (69%)
Frame = +3
Query: 357 EGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
+ + RE +F+T+KLWN+ H E V PALRK+L Q
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQ 103
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 81.4 bits (192), Expect = 4e-15
Identities = 42/117 (35%), Positives = 62/117 (52%), Gaps = 10/117 (8%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMFENDT----------LLDNVDFLDTWRGMIDAKKLGLTKS 600
L +L LEY+DLYL+HWP A D D+ + +TW+ + GL ++
Sbjct: 99 LADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQA 158
Query: 601 IGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
+G+SNFN QI I+ +P+ LQ+E + L Q EL C+ + V AY+P GS
Sbjct: 159 LGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGS 215
Score = 47.2 bits (107), Expect = 8e-05
Identities = 27/66 (40%), Positives = 38/66 (57%)
Frame = +2
Query: 155 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 334
L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G
Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58
Query: 335 ALXQEI 352
AL +++
Sbjct: 59 ALKEDV 64
Score = 42.7 bits (96), Expect = 0.002
Identities = 18/36 (50%), Positives = 25/36 (69%)
Frame = +3
Query: 357 EGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
+ + RE +F+T+KLWN+ H E V PALRK+L Q
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQ 103
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 81.4 bits (192), Expect = 4e-15
Identities = 42/117 (35%), Positives = 62/117 (52%), Gaps = 10/117 (8%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMFENDT----------LLDNVDFLDTWRGMIDAKKLGLTKS 600
L +L LEY+DLYL+HWP A D D+ + +TW+ + GL ++
Sbjct: 99 LADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQA 158
Query: 601 IGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
+G+SNFN QI I+ +P+ LQ+E + L Q EL C+ + V AY+P GS
Sbjct: 159 LGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGS 215
Score = 47.2 bits (107), Expect = 8e-05
Identities = 27/66 (40%), Positives = 38/66 (57%)
Frame = +2
Query: 155 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 334
L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G
Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58
Query: 335 ALXQEI 352
AL +++
Sbjct: 59 ALKEDV 64
Score = 42.7 bits (96), Expect = 0.002
Identities = 18/36 (50%), Positives = 25/36 (69%)
Frame = +3
Query: 357 EGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
+ + RE +F+T+KLWN+ H E V PALRK+L Q
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQ 103
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 81.4 bits (192), Expect = 4e-15
Identities = 42/117 (35%), Positives = 62/117 (52%), Gaps = 10/117 (8%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMFENDT----------LLDNVDFLDTWRGMIDAKKLGLTKS 600
L +L LEY+DLYL+HWP A D D+ + +TW+ + GL ++
Sbjct: 99 LADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQA 158
Query: 601 IGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
+G+SNFN QI I+ +P+ LQ+E + L Q EL C+ + V AY+P GS
Sbjct: 159 LGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGS 215
Score = 47.2 bits (107), Expect = 8e-05
Identities = 27/66 (40%), Positives = 38/66 (57%)
Frame = +2
Query: 155 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 334
L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G
Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58
Query: 335 ALXQEI 352
AL +++
Sbjct: 59 ALKEDV 64
Score = 42.7 bits (96), Expect = 0.002
Identities = 18/36 (50%), Positives = 25/36 (69%)
Frame = +3
Query: 357 EGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
+ + RE +F+T+KLWN+ H E V PALRK+L Q
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQ 103
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 81.4 bits (192), Expect = 4e-15
Identities = 42/117 (35%), Positives = 62/117 (52%), Gaps = 10/117 (8%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMFENDT----------LLDNVDFLDTWRGMIDAKKLGLTKS 600
L +L LEY+DLYL+HWP A D D+ + +TW+ + GL ++
Sbjct: 99 LADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQA 158
Query: 601 IGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
+G+SNFN QI I+ +P+ LQ+E + L Q EL C+ + V AY+P GS
Sbjct: 159 LGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGS 215
Score = 47.2 bits (107), Expect = 8e-05
Identities = 27/66 (40%), Positives = 38/66 (57%)
Frame = +2
Query: 155 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 334
L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G
Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58
Query: 335 ALXQEI 352
AL +++
Sbjct: 59 ALKEDV 64
Score = 42.7 bits (96), Expect = 0.002
Identities = 18/36 (50%), Positives = 25/36 (69%)
Frame = +3
Query: 357 EGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
+ + RE +F+T+KLWN+ H E V PALRK+L Q
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQ 103
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 81.4 bits (192), Expect = 4e-15
Identities = 42/117 (35%), Positives = 62/117 (52%), Gaps = 10/117 (8%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMFENDT----------LLDNVDFLDTWRGMIDAKKLGLTKS 600
L +L LEY+DLYL+HWP A D D+ + +TW+ + GL ++
Sbjct: 99 LADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQA 158
Query: 601 IGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
+G+SNFN QI I+ +P+ LQ+E + L Q EL C+ + V AY+P GS
Sbjct: 159 LGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGS 215
Score = 47.2 bits (107), Expect = 8e-05
Identities = 27/66 (40%), Positives = 38/66 (57%)
Frame = +2
Query: 155 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 334
L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G
Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58
Query: 335 ALXQEI 352
AL +++
Sbjct: 59 ALKEDV 64
Score = 42.7 bits (96), Expect = 0.002
Identities = 18/36 (50%), Positives = 25/36 (69%)
Frame = +3
Query: 357 EGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
+ + RE +F+T+KLWN+ H E V PALRK+L Q
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQ 103
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 81.0 bits (191), Expect = 5e-15
Identities = 45/119 (37%), Positives = 65/119 (54%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMFENDTLLDNVD----------FLDTWRGMIDAKKLGLTKS 600
L +L L Y+D+YLIHWP D L D FLD W M + GL K+
Sbjct: 97 LKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKA 156
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
+G+SNF+ QI+++++ GL+ KP Q+E + L Q +L ++C I V AY+P GS
Sbjct: 157 LGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGS 215
Score = 56.0 bits (129), Expect = 2e-07
Identities = 32/79 (40%), Positives = 47/79 (59%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 328
++LS+ +P+V LGTW P GKV ++AV A++AGY HID AY Y E +V
Sbjct: 5 VELSTKAKMPIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 329 GRALXQEILRRTKKRIYLY 385
G A+ ++I + KR L+
Sbjct: 56 GEAIQEKIQEKAVKREDLF 74
Score = 33.9 bits (74), Expect = 0.80
Identities = 16/45 (35%), Positives = 27/45 (60%)
Frame = +3
Query: 357 EGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQPGIRRSVFD 491
+ +KRE +FI +KLW ++ ER P +RK+ K+ ++ S D
Sbjct: 66 KAVKREDLFIVSKLWPTFFER----PLVRKAFEKTLKDLKLSYLD 106
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 81.0 bits (191), Expect = 5e-15
Identities = 45/119 (37%), Positives = 65/119 (54%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMFENDTLLDNVD----------FLDTWRGMIDAKKLGLTKS 600
L +L L Y+D+YLIHWP D L D FLD W M + GL K+
Sbjct: 97 LKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKA 156
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
+G+SNF+ QI+++++ GL+ KP Q+E + L Q +L ++C I V AY+P GS
Sbjct: 157 LGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGS 215
Score = 56.0 bits (129), Expect = 2e-07
Identities = 32/79 (40%), Positives = 47/79 (59%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 328
++LS+ +P+V LGTW P GKV ++AV A++AGY HID AY Y E +V
Sbjct: 5 VELSTKAKMPIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 329 GRALXQEILRRTKKRIYLY 385
G A+ ++I + KR L+
Sbjct: 56 GEAIQEKIQEKAVKREDLF 74
Score = 33.9 bits (74), Expect = 0.80
Identities = 16/45 (35%), Positives = 27/45 (60%)
Frame = +3
Query: 357 EGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQPGIRRSVFD 491
+ +KRE +FI +KLW ++ ER P +RK+ K+ ++ S D
Sbjct: 66 KAVKREDLFIVSKLWPTFFER----PLVRKAFEKTLKDLKLSYLD 106
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 81.0 bits (191), Expect = 5e-15
Identities = 45/119 (37%), Positives = 65/119 (54%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMFENDTLLDNVD----------FLDTWRGMIDAKKLGLTKS 600
L +L L Y+D+YLIHWP D L D FLD W M + GL K+
Sbjct: 97 LKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKA 156
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
+G+SNF+ QI+++++ GL+ KP Q+E + L Q +L ++C I V AY+P GS
Sbjct: 157 LGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGS 215
Score = 56.0 bits (129), Expect = 2e-07
Identities = 32/79 (40%), Positives = 47/79 (59%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 328
++LS+ +P+V LGTW P GKV ++AV A++AGY HID AY Y E +V
Sbjct: 5 VELSTKAKMPIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 329 GRALXQEILRRTKKRIYLY 385
G A+ ++I + KR L+
Sbjct: 56 GEAIQEKIQEKAVKREDLF 74
Score = 33.9 bits (74), Expect = 0.80
Identities = 16/45 (35%), Positives = 27/45 (60%)
Frame = +3
Query: 357 EGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQPGIRRSVFD 491
+ +KRE +FI +KLW ++ ER P +RK+ K+ ++ S D
Sbjct: 66 KAVKREDLFIVSKLWPTFFER----PLVRKAFEKTLKDLKLSYLD 106
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 81.0 bits (191), Expect = 5e-15
Identities = 45/119 (37%), Positives = 65/119 (54%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMFENDTLLDNVD----------FLDTWRGMIDAKKLGLTKS 600
L +L L Y+D+YLIHWP D L D FLD W M + GL K+
Sbjct: 97 LKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKA 156
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
+G+SNF+ QI+++++ GL+ KP Q+E + L Q +L ++C I V AY+P GS
Sbjct: 157 LGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGS 215
Score = 56.0 bits (129), Expect = 2e-07
Identities = 32/79 (40%), Positives = 47/79 (59%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 328
++LS+ +P+V LGTW P GKV ++AV A++AGY HID AY Y E +V
Sbjct: 5 VELSTKAKMPIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 329 GRALXQEILRRTKKRIYLY 385
G A+ ++I + KR L+
Sbjct: 56 GEAIQEKIQEKAVKREDLF 74
Score = 33.9 bits (74), Expect = 0.80
Identities = 16/45 (35%), Positives = 27/45 (60%)
Frame = +3
Query: 357 EGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQPGIRRSVFD 491
+ +KRE +FI +KLW ++ ER P +RK+ K+ ++ S D
Sbjct: 66 KAVKREDLFIVSKLWPTFFER----PLVRKAFEKTLKDLKLSYLD 106
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 81.0 bits (191), Expect = 5e-15
Identities = 45/119 (37%), Positives = 65/119 (54%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMFENDTLLDNVD----------FLDTWRGMIDAKKLGLTKS 600
L +L L Y+D+YLIHWP D L D FLD W M + GL K+
Sbjct: 97 LKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKA 156
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
+G+SNF+ QI+++++ GL+ KP Q+E + L Q +L ++C I V AY+P GS
Sbjct: 157 LGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGS 215
Score = 56.0 bits (129), Expect = 2e-07
Identities = 32/79 (40%), Positives = 47/79 (59%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 328
++LS+ +P+V LGTW P GKV ++AV A++AGY HID AY Y E +V
Sbjct: 5 VELSTKAKMPIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 329 GRALXQEILRRTKKRIYLY 385
G A+ ++I + KR L+
Sbjct: 56 GEAIQEKIQEKAVKREDLF 74
Score = 33.9 bits (74), Expect = 0.80
Identities = 16/45 (35%), Positives = 27/45 (60%)
Frame = +3
Query: 357 EGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQPGIRRSVFD 491
+ +KRE +FI +KLW ++ ER P +RK+ K+ ++ S D
Sbjct: 66 KAVKREDLFIVSKLWPTFFER----PLVRKAFEKTLKDLKLSYLD 106
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 79.8 bits (188), Expect = 1e-14
Identities = 49/119 (41%), Positives = 69/119 (57%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAM------FEND----TLLDNVDFLDTWRGMIDAKKLGLTKS 600
L +L L+Y+DLYLIHWP F D + + + LDT M + GL K+
Sbjct: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTRAAMEELVDEGLVKA 156
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
IGISNFN Q++ I++ GL+ KP+ QIE + L Q +L ++C+ IVV AY+P GS
Sbjct: 157 IGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGS 215
Score = 50.0 bits (114), Expect = 1e-05
Identities = 28/79 (35%), Positives = 46/79 (58%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 328
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 329 GRALXQEILRRTKKRIYLY 385
G A+ +++ + KR L+
Sbjct: 56 GVAIQEKLREQVVKREELF 74
Score = 35.5 bits (78), Expect = 0.26
Identities = 15/30 (50%), Positives = 22/30 (73%)
Frame = +3
Query: 363 LKRESIFITTKLWNSYHEREQVIPALRKSL 452
+KRE +FI +KLW +YHE+ V A +K+L
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTL 97
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 78.2 bits (184), Expect = 4e-14
Identities = 44/119 (36%), Positives = 64/119 (53%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMFENDTLLDNVD----------FLDTWRGMIDAKKLGLTKS 600
L + L Y+D+YLIHWP D L D FLD W M + GL K+
Sbjct: 97 LKDPKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKA 156
Query: 601 IGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
+G+SNF+ QI+++++ GL+ KP Q+E + L Q +L ++C I V AY+P GS
Sbjct: 157 LGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGS 215
Score = 56.0 bits (129), Expect = 2e-07
Identities = 32/79 (40%), Positives = 47/79 (59%)
Frame = +2
Query: 149 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 328
++LS+ +P+V LGTW P GKV ++AV A++AGY HID AY Y E +V
Sbjct: 5 VELSTKAKMPIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 329 GRALXQEILRRTKKRIYLY 385
G A+ ++I + KR L+
Sbjct: 56 GEAIQEKIQEKAVKREDLF 74
Score = 33.1 bits (72), Expect = 1.4
Identities = 14/32 (43%), Positives = 21/32 (65%)
Frame = +3
Query: 357 EGLKRESIFITTKLWNSYHEREQVIPALRKSL 452
+ +KRE +FI +KLW ++ ER V A K+L
Sbjct: 66 KAVKREDLFIASKLWPTFFERPLVRKAFEKTL 97
>AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens
cDNA FLJ25413 fis, clone TST03402, highly similar to
3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ).
Length = 146
Score = 73.7 bits (173), Expect = 8e-13
Identities = 34/75 (45%), Positives = 52/75 (69%), Gaps = 2/75 (2%)
Frame = +1
Query: 553 TWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFC 726
TW M K GL KS+G+SNFN+ Q++ I++ GL+ KP + Q+E + QP+L KFC
Sbjct: 28 TWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFC 87
Query: 727 RENDIVVMAYTPFGS 771
+++DIV+ AY+P G+
Sbjct: 88 QQHDIVITAYSPLGT 102
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 55.6 bits (128), Expect(2) = 6e-11
Identities = 28/65 (43%), Positives = 40/65 (61%), Gaps = 2/65 (3%)
Frame = +1
Query: 517 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIELN 690
N + + DFLDTW M D GL K+IG+SNFN EQ++R+++ GL KP QI +
Sbjct: 139 NMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQILIR 198
Query: 691 LNLQQ 705
+Q+
Sbjct: 199 FQIQR 203
Score = 37.9 bits (84), Expect = 0.049
Identities = 26/73 (35%), Positives = 36/73 (49%)
Frame = +2
Query: 167 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQ 346
G+IP V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 347 EILRRTKKRIYLY 385
+I +R L+
Sbjct: 53 KIKEGAVRREDLF 65
Score = 36.7 bits (81), Expect = 0.11
Identities = 18/36 (50%), Positives = 24/36 (66%), Gaps = 1/36 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSL 452
K EG ++RE +FI TKLW + H++ V A RKSL
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSL 88
Score = 31.9 bits (69), Expect(2) = 6e-11
Identities = 12/18 (66%), Positives = 14/18 (77%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPI 504
L L L Y+DLYLIHWP+
Sbjct: 88 LKALKLNYLDLYLIHWPM 105
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 55.6 bits (128), Expect(2) = 6e-11
Identities = 28/65 (43%), Positives = 40/65 (61%), Gaps = 2/65 (3%)
Frame = +1
Query: 517 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIELN 690
N + + DFLDTW M D GL K+IG+SNFN EQ++R+++ GL KP QI +
Sbjct: 139 NMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQILIR 198
Query: 691 LNLQQ 705
+Q+
Sbjct: 199 FQIQR 203
Score = 37.9 bits (84), Expect = 0.049
Identities = 26/73 (35%), Positives = 36/73 (49%)
Frame = +2
Query: 167 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQ 346
G+IP V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 347 EILRRTKKRIYLY 385
+I +R L+
Sbjct: 53 KIKEGAVRREDLF 65
Score = 36.7 bits (81), Expect = 0.11
Identities = 18/36 (50%), Positives = 24/36 (66%), Gaps = 1/36 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSL 452
K EG ++RE +FI TKLW + H++ V A RKSL
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSL 88
Score = 31.9 bits (69), Expect(2) = 6e-11
Identities = 12/18 (66%), Positives = 14/18 (77%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPI 504
L L L Y+DLYLIHWP+
Sbjct: 88 LKALKLNYLDLYLIHWPM 105
>BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 48.8 bits (111), Expect = 3e-05
Identities = 26/77 (33%), Positives = 45/77 (58%), Gaps = 1/77 (1%)
Frame = +2
Query: 146 TLQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 322
+++L+ G +PV+ GT+ H PK + + T A++ G+ HID+AY Y E+
Sbjct: 10 SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEE 62
Query: 323 QVGRALXQEILRRTKKR 373
+VG+A+ ++I T KR
Sbjct: 63 EVGQAIWEKIADGTVKR 79
Score = 39.9 bits (89), Expect = 0.012
Identities = 20/42 (47%), Positives = 27/42 (64%), Gaps = 1/42 (2%)
Frame = +3
Query: 345 KKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQP 467
+K ++G +KRE IF T KLW ++ E V PAL +SL K P
Sbjct: 70 EKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGP 111
>BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 48.8 bits (111), Expect = 3e-05
Identities = 26/77 (33%), Positives = 45/77 (58%), Gaps = 1/77 (1%)
Frame = +2
Query: 146 TLQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 322
+++L+ G +PV+ GT+ H PK + + T A++ G+ HID+AY Y E+
Sbjct: 10 SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEE 62
Query: 323 QVGRALXQEILRRTKKR 373
+VG+A+ ++I T KR
Sbjct: 63 EVGQAIWEKIADGTVKR 79
Score = 39.9 bits (89), Expect = 0.012
Identities = 20/42 (47%), Positives = 27/42 (64%), Gaps = 1/42 (2%)
Frame = +3
Query: 345 KKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQP 467
+K ++G +KRE IF T KLW ++ E V PAL +SL K P
Sbjct: 70 EKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGP 111
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 48.8 bits (111), Expect = 3e-05
Identities = 26/77 (33%), Positives = 45/77 (58%), Gaps = 1/77 (1%)
Frame = +2
Query: 146 TLQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 322
+++L+ G +PV+ GT+ H PK + + T A++ G+ HID+AY Y E+
Sbjct: 10 SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEE 62
Query: 323 QVGRALXQEILRRTKKR 373
+VG+A+ ++I T KR
Sbjct: 63 EVGQAIWEKIADGTVKR 79
Score = 39.9 bits (89), Expect = 0.012
Identities = 20/42 (47%), Positives = 27/42 (64%), Gaps = 1/42 (2%)
Frame = +3
Query: 345 KKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQP 467
+K ++G +KRE IF T KLW ++ E V PAL +SL K P
Sbjct: 70 EKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGP 111
Score = 38.7 bits (86), Expect = 0.028
Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMFE-----------NDTLLDNVDFLDTWRGMIDAKKLGLTK 597
L L +YVDL++IH P AM + + +L+ V+ DTW + K GL
Sbjct: 106 LKKLGPDYVDLFIIHVPFAMKQPGKELLPKDASGEIILETVELCDTWELELILNKPGLRY 165
Query: 598 SIGISNFNQEQIQRIIDSGLEKPSALQI-ELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
KP+ Q+ E + L Q +L +FC+ DIV++AY+ GS
Sbjct: 166 ---------------------KPTCNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALGS 203
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 48.8 bits (111), Expect = 3e-05
Identities = 26/77 (33%), Positives = 45/77 (58%), Gaps = 1/77 (1%)
Frame = +2
Query: 146 TLQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 322
+++L+ G +PV+ GT+ H PK + + T A++ G+ HID+AY Y E+
Sbjct: 10 SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEE 62
Query: 323 QVGRALXQEILRRTKKR 373
+VG+A+ ++I T KR
Sbjct: 63 EVGQAIWEKIADGTVKR 79
Score = 39.9 bits (89), Expect = 0.012
Identities = 20/42 (47%), Positives = 27/42 (64%), Gaps = 1/42 (2%)
Frame = +3
Query: 345 KKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQP 467
+K ++G +KRE IF T KLW ++ E V PAL +SL K P
Sbjct: 70 EKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGP 111
Score = 38.7 bits (86), Expect = 0.028
Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 12/119 (10%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMFE-----------NDTLLDNVDFLDTWRGMIDAKKLGLTK 597
L L +YVDL++IH P AM + + +L+ V+ DTW + K GL
Sbjct: 106 LKKLGPDYVDLFIIHVPFAMKQPGKELLPKDASGEIILETVELCDTWELELILNKPGLRY 165
Query: 598 SIGISNFNQEQIQRIIDSGLEKPSALQI-ELNLNLQQPELFKFCRENDIVVMAYTPFGS 771
KP+ Q+ E + L Q +L +FC+ DIV++AY+ GS
Sbjct: 166 ---------------------KPTCNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALGS 203
>AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ16347 fis, clone TESTI2036288, moderately
similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
Length = 129
Score = 48.8 bits (111), Expect = 3e-05
Identities = 26/77 (33%), Positives = 45/77 (58%), Gaps = 1/77 (1%)
Frame = +2
Query: 146 TLQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 322
+++L+ G +PV+ GT+ H PK + + T A++ G+ HID+AY Y E+
Sbjct: 10 SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEE 62
Query: 323 QVGRALXQEILRRTKKR 373
+VG+A+ ++I T KR
Sbjct: 63 EVGQAIWEKIADGTVKR 79
Score = 39.9 bits (89), Expect = 0.012
Identities = 20/42 (47%), Positives = 27/42 (64%), Gaps = 1/42 (2%)
Frame = +3
Query: 345 KKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQP 467
+K ++G +KRE IF T KLW ++ E V PAL +SL K P
Sbjct: 70 EKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGP 111
>AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydela) protein.
Length = 147
Score = 47.2 bits (107), Expect = 8e-05
Identities = 27/66 (40%), Positives = 38/66 (57%)
Frame = +2
Query: 155 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 334
L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G
Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58
Query: 335 ALXQEI 352
AL +++
Sbjct: 59 ALKEDV 64
Score = 42.7 bits (96), Expect = 0.002
Identities = 18/36 (50%), Positives = 25/36 (69%)
Frame = +3
Query: 357 EGLKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
+ + RE +F+T+KLWN+ H E V PALRK+L Q
Sbjct: 68 KAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQ 103
Score = 35.9 bits (79), Expect = 0.20
Identities = 14/24 (58%), Positives = 17/24 (70%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPIAMFEND 522
L +L LEY+DLYL+HWP A D
Sbjct: 99 LADLQLEYLDLYLMHWPYAFERGD 122
>AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto
reductase protein.
Length = 130
Score = 46.0 bits (104), Expect = 2e-04
Identities = 25/76 (32%), Positives = 47/76 (61%)
Frame = +2
Query: 146 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 325
+++L+ G +P++ GT + + V ++N E+AV A++ GY HID+AY + E+
Sbjct: 8 SVKLNDGKFMPILGFGTSVARK-----VAMSN-VEEAVQVAIDVGYRHIDSAYTHLNEEG 61
Query: 326 VGRALXQEILRRTKKR 373
+G+A+ ++I T KR
Sbjct: 62 IGQAIRKKIANGTVKR 77
Score = 34.3 bits (75), Expect = 0.60
Identities = 18/41 (43%), Positives = 24/41 (58%), Gaps = 1/41 (2%)
Frame = +3
Query: 345 KKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLXKSQ 464
KK + G +KR+ IF TTK+W ++ E V L SL K Q
Sbjct: 68 KKIANGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKKLQ 108
>AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthase
protein.
Length = 67
Score = 46.0 bits (104), Expect = 2e-04
Identities = 23/49 (46%), Positives = 31/49 (63%), Gaps = 2/49 (4%)
Frame = +1
Query: 526 LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KP 666
+ D VD TW M K GL KSIG+SNFN+ Q++ I++ GL+ KP
Sbjct: 15 IFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKP 63
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 37.9 bits (84), Expect = 0.049
Identities = 26/73 (35%), Positives = 36/73 (49%)
Frame = +2
Query: 167 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALXQ 346
G+IP V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 347 EILRRTKKRIYLY 385
+I +R L+
Sbjct: 53 KIKEGAVRREDLF 65
Score = 36.7 bits (81), Expect = 0.11
Identities = 18/36 (50%), Positives = 24/36 (66%), Gaps = 1/36 (2%)
Frame = +3
Query: 348 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSL 452
K EG ++RE +FI TKLW + H++ V A RKSL
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSL 88
Score = 31.9 bits (69), Expect(2) = 0.55
Identities = 12/18 (66%), Positives = 14/18 (77%)
Frame = +1
Query: 451 LXNLNLEYVDLYLIHWPI 504
L L L Y+DLYLIHWP+
Sbjct: 88 LKALKLNYLDLYLIHWPM 105
Score = 21.4 bits (43), Expect(2) = 0.55
Identities = 8/18 (44%), Positives = 11/18 (61%)
Frame = +1
Query: 517 NDTLLDNVDFLDTWRGMI 570
N + + DFLDTW +I
Sbjct: 139 NMVIPSDTDFLDTWEILI 156
>BC054001-1|AAH54001.1| 438|Homo sapiens OLFML2A protein protein.
Length = 438
Score = 35.9 bits (79), Expect = 0.20
Identities = 20/50 (40%), Positives = 25/50 (50%)
Frame = +3
Query: 672 FADRVKPQPATTRALQVLPRKRHSGDGVHSLRVAVPRAXLNQTLLRRGLT 821
FADR P+P + LQV ++ SG G A PRA Q + RG T
Sbjct: 29 FADRGLPKPPKEKLLQVEKLRKESGKGSFLQPTAKPRALAQQQAVIRGFT 78
>AY358185-1|AAQ88552.1| 613|Homo sapiens olfactomedin-like protein.
Length = 613
Score = 35.9 bits (79), Expect = 0.20
Identities = 20/50 (40%), Positives = 25/50 (50%)
Frame = +3
Query: 672 FADRVKPQPATTRALQVLPRKRHSGDGVHSLRVAVPRAXLNQTLLRRGLT 821
FADR P+P + LQV ++ SG G A PRA Q + RG T
Sbjct: 204 FADRGLPKPPKEKLLQVEKLRKESGKGSFLQPTAKPRALAQQQAVIRGFT 253
>AL354928-5|CAI39636.2| 438|Homo sapiens olfactomedin-like 2A
protein.
Length = 438
Score = 35.9 bits (79), Expect = 0.20
Identities = 20/50 (40%), Positives = 25/50 (50%)
Frame = +3
Query: 672 FADRVKPQPATTRALQVLPRKRHSGDGVHSLRVAVPRAXLNQTLLRRGLT 821
FADR P+P + LQV ++ SG G A PRA Q + RG T
Sbjct: 29 FADRGLPKPPKEKLLQVEKLRKESGKGSFLQPTAKPRALAQQQAVIRGFT 78
>AL354928-4|CAI39635.2| 652|Homo sapiens olfactomedin-like 2A
protein.
Length = 652
Score = 35.9 bits (79), Expect = 0.20
Identities = 20/50 (40%), Positives = 25/50 (50%)
Frame = +3
Query: 672 FADRVKPQPATTRALQVLPRKRHSGDGVHSLRVAVPRAXLNQTLLRRGLT 821
FADR P+P + LQV ++ SG G A PRA Q + RG T
Sbjct: 243 FADRGLPKPPKEKLLQVEKLRKESGKGSFLQPTAKPRALAQQQAVIRGFT 292
>AL354928-3|CAI39634.1| 318|Homo sapiens olfactomedin-like 2A
protein.
Length = 318
Score = 35.9 bits (79), Expect = 0.20
Identities = 20/50 (40%), Positives = 25/50 (50%)
Frame = +3
Query: 672 FADRVKPQPATTRALQVLPRKRHSGDGVHSLRVAVPRAXLNQTLLRRGLT 821
FADR P+P + LQV ++ SG G A PRA Q + RG T
Sbjct: 207 FADRGLPKPPKEKLLQVEKLRKESGKGSFLQPTAKPRALAQQQAVIRGFT 256
>AK074709-1|BAC11152.1| 353|Homo sapiens protein ( Homo sapiens
cDNA FLJ90228 fis, clone NT2RM2000241. ).
Length = 353
Score = 35.9 bits (79), Expect = 0.20
Identities = 20/50 (40%), Positives = 25/50 (50%)
Frame = +3
Query: 672 FADRVKPQPATTRALQVLPRKRHSGDGVHSLRVAVPRAXLNQTLLRRGLT 821
FADR P+P + LQV ++ SG G A PRA Q + RG T
Sbjct: 207 FADRGLPKPPKEKLLQVEKLRKESGKGSFLQPTAKPRALAQQQAVIRGFT 256
>AB119055-1|BAD38864.1| 652|Homo sapiens photomedin-1 protein.
Length = 652
Score = 35.9 bits (79), Expect = 0.20
Identities = 20/50 (40%), Positives = 25/50 (50%)
Frame = +3
Query: 672 FADRVKPQPATTRALQVLPRKRHSGDGVHSLRVAVPRAXLNQTLLRRGLT 821
FADR P+P + LQV ++ SG G A PRA Q + RG T
Sbjct: 243 FADRGLPKPPKEKLLQVEKLRKESGKGSFLQPTAKPRALAQQQAVIRGFT 292
>BC029488-1|AAH29488.1| 294|Homo sapiens sperm acrosome associated
1 protein.
Length = 294
Score = 31.1 bits (67), Expect = 5.6
Identities = 17/56 (30%), Positives = 25/56 (44%)
Frame = +2
Query: 101 CLSALCFTSAELIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYA 268
C + L T L++ LQ + G N+ L H +G+ ND+E A YA
Sbjct: 8 CSAGLLMTVGWLLLAGLQSARGTNVTAAVQDAGLAHEGEGEEETENNDSETAENYA 63
>AL136096-1|CAI19915.1| 294|Homo sapiens sperm acrosome associated
1 protein.
Length = 294
Score = 31.1 bits (67), Expect = 5.6
Identities = 17/56 (30%), Positives = 25/56 (44%)
Frame = +2
Query: 101 CLSALCFTSAELIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYA 268
C + L T L++ LQ + G N+ L H +G+ ND+E A YA
Sbjct: 8 CSAGLLMTVGWLLLAGLQSARGTNVTAAVQDAGLAHEGEGEEETENNDSETAENYA 63
>AF203447-1|AAG31422.1| 294|Homo sapiens sperm acrosome membrane
protein SAMP32 protein.
Length = 294
Score = 31.1 bits (67), Expect = 5.6
Identities = 17/56 (30%), Positives = 25/56 (44%)
Frame = +2
Query: 101 CLSALCFTSAELIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYA 268
C + L T L++ LQ + G N+ L H +G+ ND+E A YA
Sbjct: 8 CSAGLLMTVGWLLLAGLQSARGTNVTAAVQDAGLAHEGEGEEETENNDSETAENYA 63
>AK092420-1|BAC03884.1| 357|Homo sapiens protein ( Homo sapiens
cDNA FLJ35101 fis, clone PLACE6006418, weakly similar to
PUTATIVE PRE-MRNA SPLICING FACTOR ATP-DEPENDENT RNA
HELICASE. ).
Length = 357
Score = 30.3 bits (65), Expect = 9.8
Identities = 15/40 (37%), Positives = 25/40 (62%)
Frame = +1
Query: 568 IDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 687
+DA+K+ +T + +F+ IQ +IDSGLE S + E+
Sbjct: 315 MDARKVVVTHWLADFSFSLPSIQHVIDSGLELRSVSEREI 354
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 133,335,815
Number of Sequences: 237096
Number of extensions: 3048553
Number of successful extensions: 12195
Number of sequences better than 10.0: 103
Number of HSP's better than 10.0 without gapping: 11514
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 12034
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11437206932
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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