Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP24_F_P14
(898 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Y14487-1|CAB54840.1| 347|Homo sapiens cytosolic serine hydroxym... 385 e-106
Y14485-1|CAB54838.1| 483|Homo sapiens cytosolic serine hydroxym... 385 e-106
L23928-3|AAA36019.1| 403|Homo sapiens serine hydroxymethyltrans... 385 e-106
L23928-2|AAA36018.1| 444|Homo sapiens serine hydroxymethyltrans... 385 e-106
L23928-1|AAA36020.1| 483|Homo sapiens serine hydroxymethyltrans... 385 e-106
L11931-1|AAA63257.1| 483|Homo sapiens serine hydroxymethyltrans... 385 e-106
BC038598-1|AAH38598.1| 483|Homo sapiens serine hydroxymethyltra... 385 e-106
BC022874-1|AAH22874.1| 444|Homo sapiens serine hydroxymethyltra... 385 e-106
BC007979-1|AAH07979.1| 483|Homo sapiens serine hydroxymethyltra... 385 e-106
AK223552-1|BAD97272.1| 483|Homo sapiens serine hydroxymethyltra... 385 e-106
U23143-1|AAA64572.1| 483|Homo sapiens mitochondrial serine hydr... 355 2e-97
L11932-1|AAA63258.1| 474|Homo sapiens serine hydroxymethyltrans... 355 2e-97
BT006866-1|AAP35512.1| 504|Homo sapiens serine hydroxymethyltra... 355 2e-97
BC044211-1|AAH44211.1| 504|Homo sapiens serine hydroxymethyltra... 355 2e-97
BC013677-1|AAH13677.1| 504|Homo sapiens serine hydroxymethyltra... 355 2e-97
BC011911-1|AAH11911.1| 504|Homo sapiens serine hydroxymethyltra... 355 2e-97
AK223555-1|BAD97275.1| 504|Homo sapiens serine hydroxymethyltra... 355 2e-97
BC032584-1|AAH32584.1| 494|Homo sapiens SHMT2 protein protein. 326 7e-89
BC091501-1|AAH91501.1| 480|Homo sapiens SHMT2 protein protein. 289 7e-78
Y14486-1|CAB54839.1| 310|Homo sapiens cytosolic serine hydroxym... 147 4e-35
Y14488-1|CAB54841.1| 129|Homo sapiens 14 kDa protein protein. 55 3e-07
AK055053-1|BAB70847.1| 135|Homo sapiens protein. 40 0.016
>Y14487-1|CAB54840.1| 347|Homo sapiens cytosolic serine
hydroxymethyltransferase protein.
Length = 347
Score = 385 bits (947), Expect = e-106
Identities = 178/245 (72%), Positives = 207/245 (84%)
Frame = +3
Query: 153 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 332
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 333 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 512
QRYYGG E+IDE+E L Q R+L+AY+L + WGVNVQPYSGSPANFAVYT +VEPHGRIM
Sbjct: 80 QRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIM 139
Query: 513 GLDLPDGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLII 692
GLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P +G I+YD+L E A+LF P+LII
Sbjct: 140 GLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLII 199
Query: 693 AGMSCYSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYCDIVTTTTHKTL 872
AG SCYSR L+Y R R+IAD NGAYLMADMAH+SGLVAAGV+PSPFE+C +VTTTTHKTL
Sbjct: 200 AGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTL 259
Query: 873 RGPRA 887
RG RA
Sbjct: 260 RGCRA 264
>Y14485-1|CAB54838.1| 483|Homo sapiens cytosolic serine
hydroxymethyltransferase protein.
Length = 483
Score = 385 bits (947), Expect = e-106
Identities = 178/245 (72%), Positives = 207/245 (84%)
Frame = +3
Query: 153 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 332
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 333 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 512
QRYYGG E+IDE+E L Q R+L+AY+L + WGVNVQPYSGSPANFAVYT +VEPHGRIM
Sbjct: 80 QRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIM 139
Query: 513 GLDLPDGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLII 692
GLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P +G I+YD+L E A+LF P+LII
Sbjct: 140 GLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLII 199
Query: 693 AGMSCYSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYCDIVTTTTHKTL 872
AG SCYSR L+Y R R+IAD NGAYLMADMAH+SGLVAAGV+PSPFE+C +VTTTTHKTL
Sbjct: 200 AGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTL 259
Query: 873 RGPRA 887
RG RA
Sbjct: 260 RGCRA 264
>L23928-3|AAA36019.1| 403|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 403
Score = 385 bits (947), Expect = e-106
Identities = 178/245 (72%), Positives = 207/245 (84%)
Frame = +3
Query: 153 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 332
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 333 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 512
QRYYGG E+IDE+E L Q R+L+AY+L + WGVNVQPYSGSPANFAVYT +VEPHGRIM
Sbjct: 80 QRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIM 139
Query: 513 GLDLPDGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLII 692
GLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P +G I+YD+L E A+LF P+LII
Sbjct: 140 GLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLII 199
Query: 693 AGMSCYSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYCDIVTTTTHKTL 872
AG SCYSR L+Y R R+IAD NGAYLMADMAH+SGLVAAGV+PSPFE+C +VTTTTHKTL
Sbjct: 200 AGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTL 259
Query: 873 RGPRA 887
RG RA
Sbjct: 260 RGCRA 264
>L23928-2|AAA36018.1| 444|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 444
Score = 385 bits (947), Expect = e-106
Identities = 178/245 (72%), Positives = 207/245 (84%)
Frame = +3
Query: 153 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 332
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 333 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 512
QRYYGG E+IDE+E L Q R+L+AY+L + WGVNVQPYSGSPANFAVYT +VEPHGRIM
Sbjct: 80 QRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIM 139
Query: 513 GLDLPDGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLII 692
GLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P +G I+YD+L E A+LF P+LII
Sbjct: 140 GLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLII 199
Query: 693 AGMSCYSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYCDIVTTTTHKTL 872
AG SCYSR L+Y R R+IAD NGAYLMADMAH+SGLVAAGV+PSPFE+C +VTTTTHKTL
Sbjct: 200 AGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTL 259
Query: 873 RGPRA 887
RG RA
Sbjct: 260 RGCRA 264
>L23928-1|AAA36020.1| 483|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 483
Score = 385 bits (947), Expect = e-106
Identities = 178/245 (72%), Positives = 207/245 (84%)
Frame = +3
Query: 153 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 332
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 333 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 512
QRYYGG E+IDE+E L Q R+L+AY+L + WGVNVQPYSGSPANFAVYT +VEPHGRIM
Sbjct: 80 QRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIM 139
Query: 513 GLDLPDGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLII 692
GLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P +G I+YD+L E A+LF P+LII
Sbjct: 140 GLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLII 199
Query: 693 AGMSCYSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYCDIVTTTTHKTL 872
AG SCYSR L+Y R R+IAD NGAYLMADMAH+SGLVAAGV+PSPFE+C +VTTTTHKTL
Sbjct: 200 AGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTL 259
Query: 873 RGPRA 887
RG RA
Sbjct: 260 RGCRA 264
>L11931-1|AAA63257.1| 483|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 483
Score = 385 bits (947), Expect = e-106
Identities = 178/245 (72%), Positives = 207/245 (84%)
Frame = +3
Query: 153 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 332
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 333 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 512
QRYYGG E+IDE+E L Q R+L+AY+L + WGVNVQPYSGSPANFAVYT +VEPHGRIM
Sbjct: 80 QRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIM 139
Query: 513 GLDLPDGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLII 692
GLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P +G I+YD+L E A+LF P+LII
Sbjct: 140 GLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLII 199
Query: 693 AGMSCYSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYCDIVTTTTHKTL 872
AG SCYSR L+Y R R+IAD NGAYLMADMAH+SGLVAAGV+PSPFE+C +VTTTTHKTL
Sbjct: 200 AGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTL 259
Query: 873 RGPRA 887
RG RA
Sbjct: 260 RGCRA 264
>BC038598-1|AAH38598.1| 483|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) protein.
Length = 483
Score = 385 bits (947), Expect = e-106
Identities = 178/245 (72%), Positives = 207/245 (84%)
Frame = +3
Query: 153 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 332
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 333 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 512
QRYYGG E+IDE+E L Q R+L+AY+L + WGVNVQPYSGSPANFAVYT +VEPHGRIM
Sbjct: 80 QRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIM 139
Query: 513 GLDLPDGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLII 692
GLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P +G I+YD+L E A+LF P+LII
Sbjct: 140 GLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLII 199
Query: 693 AGMSCYSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYCDIVTTTTHKTL 872
AG SCYSR L+Y R R+IAD NGAYLMADMAH+SGLVAAGV+PSPFE+C +VTTTTHKTL
Sbjct: 200 AGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTL 259
Query: 873 RGPRA 887
RG RA
Sbjct: 260 RGCRA 264
>BC022874-1|AAH22874.1| 444|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) protein.
Length = 444
Score = 385 bits (947), Expect = e-106
Identities = 178/245 (72%), Positives = 207/245 (84%)
Frame = +3
Query: 153 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 332
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 333 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 512
QRYYGG E+IDE+E L Q R+L+AY+L + WGVNVQPYSGSPANFAVYT +VEPHGRIM
Sbjct: 80 QRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIM 139
Query: 513 GLDLPDGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLII 692
GLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P +G I+YD+L E A+LF P+LII
Sbjct: 140 GLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLII 199
Query: 693 AGMSCYSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYCDIVTTTTHKTL 872
AG SCYSR L+Y R R+IAD NGAYLMADMAH+SGLVAAGV+PSPFE+C +VTTTTHKTL
Sbjct: 200 AGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTL 259
Query: 873 RGPRA 887
RG RA
Sbjct: 260 RGCRA 264
>BC007979-1|AAH07979.1| 483|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) protein.
Length = 483
Score = 385 bits (947), Expect = e-106
Identities = 178/245 (72%), Positives = 207/245 (84%)
Frame = +3
Query: 153 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 332
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 333 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 512
QRYYGG E+IDE+E L Q R+L+AY+L + WGVNVQPYSGSPANFAVYT +VEPHGRIM
Sbjct: 80 QRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIM 139
Query: 513 GLDLPDGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLII 692
GLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P +G I+YD+L E A+LF P+LII
Sbjct: 140 GLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLII 199
Query: 693 AGMSCYSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYCDIVTTTTHKTL 872
AG SCYSR L+Y R R+IAD NGAYLMADMAH+SGLVAAGV+PSPFE+C +VTTTTHKTL
Sbjct: 200 AGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTL 259
Query: 873 RGPRA 887
RG RA
Sbjct: 260 RGCRA 264
>AK223552-1|BAD97272.1| 483|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) isoform 1 variant
protein.
Length = 483
Score = 385 bits (947), Expect = e-106
Identities = 178/245 (72%), Positives = 207/245 (84%)
Frame = +3
Query: 153 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 332
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 333 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 512
QRYYGG E+IDE+E L Q R+L+AY+L + WGVNVQPYSGSPANFAVYT +VEPHGRIM
Sbjct: 80 QRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIM 139
Query: 513 GLDLPDGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLII 692
GLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P +G I+YD+L E A+LF P+LII
Sbjct: 140 GLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLII 199
Query: 693 AGMSCYSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYCDIVTTTTHKTL 872
AG SCYSR L+Y R R+IAD NGAYLMADMAH+SGLVAAGV+PSPFE+C +VTTTTHKTL
Sbjct: 200 AGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTL 259
Query: 873 RGPRA 887
RG RA
Sbjct: 260 RGCRA 264
>U23143-1|AAA64572.1| 483|Homo sapiens mitochondrial serine
hydroxymethyltransferase protein.
Length = 483
Score = 355 bits (872), Expect = 2e-97
Identities = 161/240 (67%), Positives = 201/240 (83%)
Frame = +3
Query: 168 NLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPNQRYYG 347
+L ++DPE+++++ +EKDRQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 27 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 86
Query: 348 GNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMGLDLP 527
G E +DEIE+L Q R+LEA+ L +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLP
Sbjct: 87 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 146
Query: 528 DGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGMSC 707
DGGHLTHG+ + K+ISATSIFFESMPYK++PK+GLIDY++LA TA+LF+PRLIIAG S
Sbjct: 147 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 206
Query: 708 YSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYCDIVTTTTHKTLRGPRA 887
Y+R +DY R RE+ D A+L+ADMAH+SGLVAA VIPSPF++ DIVTTTTHKTLRG R+
Sbjct: 207 YARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARS 266
>L11932-1|AAA63258.1| 474|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 474
Score = 355 bits (872), Expect = 2e-97
Identities = 161/240 (67%), Positives = 201/240 (83%)
Frame = +3
Query: 168 NLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPNQRYYG 347
+L ++DPE+++++ +EKDRQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 18 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 77
Query: 348 GNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMGLDLP 527
G E +DEIE+L Q R+LEA+ L +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLP
Sbjct: 78 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 137
Query: 528 DGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGMSC 707
DGGHLTHG+ + K+ISATSIFFESMPYK++PK+GLIDY++LA TA+LF+PRLIIAG S
Sbjct: 138 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 197
Query: 708 YSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYCDIVTTTTHKTLRGPRA 887
Y+R +DY R RE+ D A+L+ADMAH+SGLVAA VIPSPF++ DIVTTTTHKTLRG R+
Sbjct: 198 YARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARS 257
>BT006866-1|AAP35512.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 355 bits (872), Expect = 2e-97
Identities = 161/240 (67%), Positives = 201/240 (83%)
Frame = +3
Query: 168 NLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPNQRYYG 347
+L ++DPE+++++ +EKDRQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 348 GNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMGLDLP 527
G E +DEIE+L Q R+LEA+ L +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLP
Sbjct: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 167
Query: 528 DGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGMSC 707
DGGHLTHG+ + K+ISATSIFFESMPYK++PK+GLIDY++LA TA+LF+PRLIIAG S
Sbjct: 168 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 227
Query: 708 YSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYCDIVTTTTHKTLRGPRA 887
Y+R +DY R RE+ D A+L+ADMAH+SGLVAA VIPSPF++ DIVTTTTHKTLRG R+
Sbjct: 228 YARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARS 287
>BC044211-1|AAH44211.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 355 bits (872), Expect = 2e-97
Identities = 161/240 (67%), Positives = 201/240 (83%)
Frame = +3
Query: 168 NLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPNQRYYG 347
+L ++DPE+++++ +EKDRQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 348 GNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMGLDLP 527
G E +DEIE+L Q R+LEA+ L +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLP
Sbjct: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 167
Query: 528 DGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGMSC 707
DGGHLTHG+ + K+ISATSIFFESMPYK++PK+GLIDY++LA TA+LF+PRLIIAG S
Sbjct: 168 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 227
Query: 708 YSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYCDIVTTTTHKTLRGPRA 887
Y+R +DY R RE+ D A+L+ADMAH+SGLVAA VIPSPF++ DIVTTTTHKTLRG R+
Sbjct: 228 YARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARS 287
>BC013677-1|AAH13677.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 355 bits (872), Expect = 2e-97
Identities = 161/240 (67%), Positives = 201/240 (83%)
Frame = +3
Query: 168 NLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPNQRYYG 347
+L ++DPE+++++ +EKDRQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 348 GNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMGLDLP 527
G E +DEIE+L Q R+LEA+ L +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLP
Sbjct: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 167
Query: 528 DGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGMSC 707
DGGHLTHG+ + K+ISATSIFFESMPYK++PK+GLIDY++LA TA+LF+PRLIIAG S
Sbjct: 168 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 227
Query: 708 YSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYCDIVTTTTHKTLRGPRA 887
Y+R +DY R RE+ D A+L+ADMAH+SGLVAA VIPSPF++ DIVTTTTHKTLRG R+
Sbjct: 228 YARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARS 287
>BC011911-1|AAH11911.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 355 bits (872), Expect = 2e-97
Identities = 161/240 (67%), Positives = 201/240 (83%)
Frame = +3
Query: 168 NLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPNQRYYG 347
+L ++DPE+++++ +EKDRQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 348 GNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMGLDLP 527
G E +DEIE+L Q R+LEA+ L +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLP
Sbjct: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 167
Query: 528 DGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGMSC 707
DGGHLTHG+ + K+ISATSIFFESMPYK++PK+GLIDY++LA TA+LF+PRLIIAG S
Sbjct: 168 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 227
Query: 708 YSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYCDIVTTTTHKTLRGPRA 887
Y+R +DY R RE+ D A+L+ADMAH+SGLVAA VIPSPF++ DIVTTTTHKTLRG R+
Sbjct: 228 YARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARS 287
>AK223555-1|BAD97275.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) variant
protein.
Length = 504
Score = 355 bits (872), Expect = 2e-97
Identities = 161/240 (67%), Positives = 201/240 (83%)
Frame = +3
Query: 168 NLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPNQRYYG 347
+L ++DPE+++++ +EKDRQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 348 GNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMGLDLP 527
G E +DEIE+L Q R+LEA+ L +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLP
Sbjct: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 167
Query: 528 DGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGMSC 707
DGGHLTHG+ + K+ISATSIFFESMPYK++PK+GLIDY++LA TA+LF+PRLIIAG S
Sbjct: 168 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 227
Query: 708 YSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYCDIVTTTTHKTLRGPRA 887
Y+R +DY R RE+ D A+L+ADMAH+SGLVAA VIPSPF++ DIVTTTTHKTLRG R+
Sbjct: 228 YARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARS 287
>BC032584-1|AAH32584.1| 494|Homo sapiens SHMT2 protein protein.
Length = 494
Score = 326 bits (801), Expect = 7e-89
Identities = 154/240 (64%), Positives = 191/240 (79%)
Frame = +3
Query: 168 NLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPNQRYYG 347
+L ++DPE+++++ +EKDRQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 348 GNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMGLDLP 527
G E +DEIE+L Q R+LEA+ L +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLP
Sbjct: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 167
Query: 528 DGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGMSC 707
DGGHLTHG+ + K+ISATSIFFESMPYK++ LA TA+LF+PRLIIAG S
Sbjct: 168 DGGHLTHGYMSDVKRISATSIFFESMPYKLN----------LALTARLFRPRLIIAGTSA 217
Query: 708 YSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYCDIVTTTTHKTLRGPRA 887
Y+R +DY R RE+ D A+L+ADMAH+SGLVAA VIPSPF++ DIVTTTTHKTLRG R+
Sbjct: 218 YARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARS 277
>BC091501-1|AAH91501.1| 480|Homo sapiens SHMT2 protein protein.
Length = 480
Score = 289 bits (710), Expect = 7e-78
Identities = 131/185 (70%), Positives = 158/185 (85%)
Frame = +3
Query: 333 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 512
QRYYGG E +DEIE+L Q R+LEA+ L +WGVNVQPYSGSPAN AVYT +++PH RIM
Sbjct: 79 QRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIM 138
Query: 513 GLDLPDGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLII 692
GLDLPDGGHLTHG+ + K+ISATSIFFESMPYK++PK+GLIDY++LA TA+LF+PRLII
Sbjct: 139 GLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLII 198
Query: 693 AGMSCYSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYCDIVTTTTHKTL 872
AG S Y+R +DY R RE+ D A+L+ADMAH+SGLVAA VIPSPF++ DIVTTTTHKTL
Sbjct: 199 AGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTL 258
Query: 873 RGPRA 887
RG R+
Sbjct: 259 RGARS 263
>Y14486-1|CAB54839.1| 310|Homo sapiens cytosolic serine
hydroxymethyltransferase protein.
Length = 310
Score = 147 bits (357), Expect = 4e-35
Identities = 67/91 (73%), Positives = 79/91 (86%)
Frame = +3
Query: 615 VDPKSGLIDYDKLAETAKLFKPRLIIAGMSCYSRCLDYKRFREIADANGAYLMADMAHVS 794
V+P +G I+YD+L E A+LF P+LIIAG SCYSR L+Y R R+IAD NGAYLMADMAH+S
Sbjct: 1 VNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHIS 60
Query: 795 GLVAAGVIPSPFEYCDIVTTTTHKTLRGPRA 887
GLVAAGV+PSPFE+C +VTTTTHKTLRG RA
Sbjct: 61 GLVAAGVVPSPFEHCHVVTTTTHKTLRGCRA 91
>Y14488-1|CAB54841.1| 129|Homo sapiens 14 kDa protein protein.
Length = 129
Score = 55.2 bits (127), Expect = 3e-07
Identities = 22/37 (59%), Positives = 29/37 (78%)
Frame = +3
Query: 336 RYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQP 446
RYYGG E+IDE+E L Q R+L+AY+L + WGV+V P
Sbjct: 65 RYYGGTEFIDELETLCQKRALQAYKLDPQCWGVDVHP 101
>AK055053-1|BAB70847.1| 135|Homo sapiens protein.
Length = 135
Score = 39.5 bits (88), Expect = 0.016
Identities = 16/30 (53%), Positives = 26/30 (86%)
Frame = +3
Query: 168 NLWEADPELFDIIVKEKDRQRAGLEMIASE 257
+L ++DPE+++++ +EKDRQ GLE+IASE
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASE 77
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 126,591,331
Number of Sequences: 237096
Number of extensions: 2647656
Number of successful extensions: 5176
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 4964
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5175
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11548247776
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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