Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP22_F_O21
(890 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AF019888-1|AAB71548.1| 168|Homo sapiens Arp2/3 complex 20 kDa s... 288 2e-77
AF006087-1|AAB64192.1| 168|Homo sapiens p20-Arc protein. 288 2e-77
BC012596-1|AAH12596.3| 78|Homo sapiens actin related protein 2... 145 2e-34
AK024110-1|BAB14828.1| 156|Homo sapiens protein ( Homo sapiens ... 143 9e-34
M23294-1|AAA52645.1| 556|Homo sapiens beta-hexosaminidase beta-... 33 1.8
M19735-1|AAA68620.1| 544|Homo sapiens beta-hexosaminidase beta-... 33 1.8
M13519-1|AAA51828.1| 572|Homo sapiens HEXB protein. 33 1.8
BT009919-1|AAP88921.1| 556|Homo sapiens hexosaminidase B (beta ... 33 1.8
BC017378-1|AAH17378.1| 556|Homo sapiens hexosaminidase B (beta ... 33 1.8
AF378118-1|AAM46114.1| 556|Homo sapiens cervical cancer proto-o... 33 1.8
AY317139-1|AAP84319.1| 983|Homo sapiens RAI14 isoform protein. 31 5.6
AF155135-1|AAF44722.1| 980|Homo sapiens novel retinal pigment e... 31 5.6
BC052988-1|AAH52988.1| 980|Homo sapiens retinoic acid induced 1... 31 7.4
AB037755-1|BAA92572.1| 989|Homo sapiens KIAA1334 protein protein. 31 7.4
>AF019888-1|AAB71548.1| 168|Homo sapiens Arp2/3 complex 20 kDa
subunit protein.
Length = 168
Score = 288 bits (706), Expect = 2e-77
Identities = 139/168 (82%), Positives = 153/168 (91%)
Frame = +2
Query: 116 MAATLKPYLTAVRHTLTAAMCLEHFSSQVVEKYTKPEVEVRTSKELLLNPVVISRNSNEK 295
M ATL+PYL+AVR TL AA+CLE+FSSQVVE++ KPEVEVR+SKELLL PV ISRN EK
Sbjct: 1 MTATLRPYLSAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVTISRNEKEK 60
Query: 296 VLIESSINSIRVSIMIKQADEIEKILCKKFMRFMMMRAENFIVLRRKPVDGYHISFLITN 475
VLIE SINS+RVSI +KQADEIEKILC KFMRFMMMRAENF +LRRKPV+GY ISFLITN
Sbjct: 61 VLIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITN 120
Query: 476 FHTEQMYKHKLVDFVIYFMEEIDKEISEMKLAVNARARICSEEFLKRF 619
FHTEQMYKHKLVDFVI+FMEEIDKEISEMKL+VNARARI +EEFLK F
Sbjct: 121 FHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF 168
>AF006087-1|AAB64192.1| 168|Homo sapiens p20-Arc protein.
Length = 168
Score = 288 bits (706), Expect = 2e-77
Identities = 139/168 (82%), Positives = 153/168 (91%)
Frame = +2
Query: 116 MAATLKPYLTAVRHTLTAAMCLEHFSSQVVEKYTKPEVEVRTSKELLLNPVVISRNSNEK 295
M ATL+PYL+AVR TL AA+CLE+FSSQVVE++ KPEVEVR+SKELLL PV ISRN EK
Sbjct: 1 MTATLRPYLSAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVTISRNEKEK 60
Query: 296 VLIESSINSIRVSIMIKQADEIEKILCKKFMRFMMMRAENFIVLRRKPVDGYHISFLITN 475
VLIE SINS+RVSI +KQADEIEKILC KFMRFMMMRAENF +LRRKPV+GY ISFLITN
Sbjct: 61 VLIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITN 120
Query: 476 FHTEQMYKHKLVDFVIYFMEEIDKEISEMKLAVNARARICSEEFLKRF 619
FHTEQMYKHKLVDFVI+FMEEIDKEISEMKL+VNARARI +EEFLK F
Sbjct: 121 FHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF 168
>BC012596-1|AAH12596.3| 78|Homo sapiens actin related protein 2/3
complex, subunit 4, 20kDa protein.
Length = 78
Score = 145 bits (352), Expect = 2e-34
Identities = 68/78 (87%), Positives = 73/78 (93%)
Frame = +2
Query: 386 MRFMMMRAENFIVLRRKPVDGYHISFLITNFHTEQMYKHKLVDFVIYFMEEIDKEISEMK 565
MRF MMRAENF +LRRKPV+GY ISFLITNFHTEQMYKHKLVDFVI+FMEEIDKEISEMK
Sbjct: 1 MRFTMMRAENFFILRRKPVEGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMK 60
Query: 566 LAVNARARICSEEFLKRF 619
L+VNARARI +EEFLK F
Sbjct: 61 LSVNARARIVAEEFLKNF 78
>AK024110-1|BAB14828.1| 156|Homo sapiens protein ( Homo sapiens
cDNA FLJ14048 fis, clone HEMBA1006650, weakly similar to
ARP2/3 COMPLEX 20 KD SUBUNIT. ).
Length = 156
Score = 143 bits (346), Expect = 9e-34
Identities = 74/111 (66%), Positives = 85/111 (76%)
Frame = +2
Query: 116 MAATLKPYLTAVRHTLTAAMCLEHFSSQVVEKYTKPEVEVRTSKELLLNPVVISRNSNEK 295
M ATL+PYL+AVR TL AA+CLE+FSSQVVE++ KPEVEVR+SKELLL PV ISRN EK
Sbjct: 1 MTATLRPYLSAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVTISRNGKEK 60
Query: 296 VLIESSINSIRVSIMIKQADEIEKILCKKFMRFMMMRAENFIVLRRKPVDG 448
VLIE SINS+RVSI +KQADEIEKILC K RA + L +DG
Sbjct: 61 VLIEGSINSVRVSIAVKQADEIEKILCHKLNSAGWPRAASRTCLSSLGLDG 111
>M23294-1|AAA52645.1| 556|Homo sapiens beta-hexosaminidase
beta-subunit protein.
Length = 556
Score = 32.7 bits (71), Expect = 1.8
Identities = 25/92 (27%), Positives = 43/92 (46%)
Frame = -1
Query: 761 YNLFVYEGNMNSITN*NYIVIKATNFSHEFILYVQ*RCFILSLKEVVKISSRILPNKFWL 582
++ VY+ + + T +I + FSH IL R + L +K ++K + NKF +
Sbjct: 175 FSQLVYQDSYGTFTINESTIIDSPRFSHRGILIDTSRHY-LPVKIILKTLDAMAFNKFNV 233
Query: 581 LH*QPISFH*FLYQFLP*SILQNRPIYAYTSV 486
LH + F YQ + L N+ Y+ + V
Sbjct: 234 LHWHIVDDQSFPYQSITFPELSNKGSYSLSHV 265
>M19735-1|AAA68620.1| 544|Homo sapiens beta-hexosaminidase
beta-subunit protein.
Length = 544
Score = 32.7 bits (71), Expect = 1.8
Identities = 25/92 (27%), Positives = 43/92 (46%)
Frame = -1
Query: 761 YNLFVYEGNMNSITN*NYIVIKATNFSHEFILYVQ*RCFILSLKEVVKISSRILPNKFWL 582
++ VY+ + + T +I + FSH IL R + L +K ++K + NKF +
Sbjct: 163 FSQLVYQDSYGTFTINESTIIDSPRFSHRGILIDTSRHY-LPVKIILKTLDAMAFNKFNV 221
Query: 581 LH*QPISFH*FLYQFLP*SILQNRPIYAYTSV 486
LH + F YQ + L N+ Y+ + V
Sbjct: 222 LHWHIVDDQSFPYQSITFPELSNKGSYSLSHV 253
>M13519-1|AAA51828.1| 572|Homo sapiens HEXB protein.
Length = 572
Score = 32.7 bits (71), Expect = 1.8
Identities = 25/92 (27%), Positives = 43/92 (46%)
Frame = -1
Query: 761 YNLFVYEGNMNSITN*NYIVIKATNFSHEFILYVQ*RCFILSLKEVVKISSRILPNKFWL 582
++ VY+ + + T +I + FSH IL R + L +K ++K + NKF +
Sbjct: 191 FSQLVYQDSYGTFTINESTIIDSPRFSHRGILIDTSRHY-LPVKIILKTLDAMAFNKFNV 249
Query: 581 LH*QPISFH*FLYQFLP*SILQNRPIYAYTSV 486
LH + F YQ + L N+ Y+ + V
Sbjct: 250 LHWHIVDDQSFPYQSITFPELSNKGSYSLSHV 281
>BT009919-1|AAP88921.1| 556|Homo sapiens hexosaminidase B (beta
polypeptide) protein.
Length = 556
Score = 32.7 bits (71), Expect = 1.8
Identities = 25/92 (27%), Positives = 43/92 (46%)
Frame = -1
Query: 761 YNLFVYEGNMNSITN*NYIVIKATNFSHEFILYVQ*RCFILSLKEVVKISSRILPNKFWL 582
++ VY+ + + T +I + FSH IL R + L +K ++K + NKF +
Sbjct: 175 FSQLVYQDSYGTFTINESTIIDSPRFSHRGILIDTSRHY-LPVKIILKTLDAMAFNKFNV 233
Query: 581 LH*QPISFH*FLYQFLP*SILQNRPIYAYTSV 486
LH + F YQ + L N+ Y+ + V
Sbjct: 234 LHWHIVDDQSFPYQSITFPELSNKGSYSLSHV 265
>BC017378-1|AAH17378.1| 556|Homo sapiens hexosaminidase B (beta
polypeptide) protein.
Length = 556
Score = 32.7 bits (71), Expect = 1.8
Identities = 25/92 (27%), Positives = 43/92 (46%)
Frame = -1
Query: 761 YNLFVYEGNMNSITN*NYIVIKATNFSHEFILYVQ*RCFILSLKEVVKISSRILPNKFWL 582
++ VY+ + + T +I + FSH IL R + L +K ++K + NKF +
Sbjct: 175 FSQLVYQDSYGTFTINESTIIDSPRFSHRGILIDTSRHY-LPVKIILKTLDAMAFNKFNV 233
Query: 581 LH*QPISFH*FLYQFLP*SILQNRPIYAYTSV 486
LH + F YQ + L N+ Y+ + V
Sbjct: 234 LHWHIVDDQSFPYQSITFPELSNKGSYSLSHV 265
>AF378118-1|AAM46114.1| 556|Homo sapiens cervical cancer
proto-oncogene 7 protein.
Length = 556
Score = 32.7 bits (71), Expect = 1.8
Identities = 25/92 (27%), Positives = 43/92 (46%)
Frame = -1
Query: 761 YNLFVYEGNMNSITN*NYIVIKATNFSHEFILYVQ*RCFILSLKEVVKISSRILPNKFWL 582
++ VY+ + + T +I + FSH IL R + L +K ++K + NKF +
Sbjct: 175 FSQLVYQDSYGTFTINESTIIDSPRFSHRGILIDTSRHY-LPVKIILKTLDAMAFNKFNV 233
Query: 581 LH*QPISFH*FLYQFLP*SILQNRPIYAYTSV 486
LH + F YQ + L N+ Y+ + V
Sbjct: 234 LHWHIVDDQSFPYQSITFPELSNKGSYSLSHV 265
>AY317139-1|AAP84319.1| 983|Homo sapiens RAI14 isoform protein.
Length = 983
Score = 31.1 bits (67), Expect = 5.6
Identities = 39/164 (23%), Positives = 74/164 (45%), Gaps = 6/164 (3%)
Frame = +2
Query: 119 AATLKPYLTAVRHTLTAAMCLEHFSSQVVEKYTKPEVEV-RTSKELL-----LNPVVISR 280
+ ++ +L + TAA +E S + E EVEV + K+LL + ++ R
Sbjct: 730 SVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPR 789
Query: 281 NSNEKVLIESSINSIRVSIMIKQADEIEKILCKKFMRFMMMRAENFIVLRRKPVDGYHIS 460
+S EK ++SS+ S VS++ + E K K + +R+E V R K
Sbjct: 790 SSYEK--LQSSLES-EVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREK-------- 838
Query: 461 FLITNFHTEQMYKHKLVDFVIYFMEEIDKEISEMKLAVNARARI 592
N T K + V+ ++ ++ +E++EMK + +++
Sbjct: 839 ---ENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKL 879
>AF155135-1|AAF44722.1| 980|Homo sapiens novel retinal pigment
epithelial cell protein protein.
Length = 980
Score = 31.1 bits (67), Expect = 5.6
Identities = 39/164 (23%), Positives = 74/164 (45%), Gaps = 6/164 (3%)
Frame = +2
Query: 119 AATLKPYLTAVRHTLTAAMCLEHFSSQVVEKYTKPEVEV-RTSKELL-----LNPVVISR 280
+ ++ +L + TAA +E S + E EVEV + K+LL + ++ R
Sbjct: 727 SVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPR 786
Query: 281 NSNEKVLIESSINSIRVSIMIKQADEIEKILCKKFMRFMMMRAENFIVLRRKPVDGYHIS 460
+S EK ++SS+ S VS++ + E K K + +R+E V R K
Sbjct: 787 SSYEK--LQSSLES-EVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREK-------- 835
Query: 461 FLITNFHTEQMYKHKLVDFVIYFMEEIDKEISEMKLAVNARARI 592
N T K + V+ ++ ++ +E++EMK + +++
Sbjct: 836 ---ENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKL 876
>BC052988-1|AAH52988.1| 980|Homo sapiens retinoic acid induced 14
protein.
Length = 980
Score = 30.7 bits (66), Expect = 7.4
Identities = 39/155 (25%), Positives = 70/155 (45%), Gaps = 6/155 (3%)
Frame = +2
Query: 119 AATLKPYLTAVRHTLTAAMCLEHFSSQVVEKYTKPEVEV-RTSKELL-----LNPVVISR 280
+ ++ +L + TAA +E S + E EVEV + K+LL + ++ R
Sbjct: 727 SVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPR 786
Query: 281 NSNEKVLIESSINSIRVSIMIKQADEIEKILCKKFMRFMMMRAENFIVLRRKPVDGYHIS 460
+S EK ++SS+ S VS++ + E K K + +R+E V R K
Sbjct: 787 SSYEK--LQSSLES-EVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREK-------- 835
Query: 461 FLITNFHTEQMYKHKLVDFVIYFMEEIDKEISEMK 565
N T K + V+ ++ ++ +E++EMK
Sbjct: 836 ---ENIQTLLKSKEQEVNELLQKFQQAQEELAEMK 867
>AB037755-1|BAA92572.1| 989|Homo sapiens KIAA1334 protein protein.
Length = 989
Score = 30.7 bits (66), Expect = 7.4
Identities = 39/155 (25%), Positives = 70/155 (45%), Gaps = 6/155 (3%)
Frame = +2
Query: 119 AATLKPYLTAVRHTLTAAMCLEHFSSQVVEKYTKPEVEV-RTSKELL-----LNPVVISR 280
+ ++ +L + TAA +E S + E EVEV + K+LL + ++ R
Sbjct: 736 SVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPR 795
Query: 281 NSNEKVLIESSINSIRVSIMIKQADEIEKILCKKFMRFMMMRAENFIVLRRKPVDGYHIS 460
+S EK ++SS+ S VS++ + E K K + +R+E V R K
Sbjct: 796 SSYEK--LQSSLES-EVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREK-------- 844
Query: 461 FLITNFHTEQMYKHKLVDFVIYFMEEIDKEISEMK 565
N T K + V+ ++ ++ +E++EMK
Sbjct: 845 ---ENIQTLLKSKEQEVNELLQKFQQAQEELAEMK 876
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 107,602,230
Number of Sequences: 237096
Number of extensions: 2086740
Number of successful extensions: 3305
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 3113
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3305
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11437206932
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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