Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP22_F_K09
(891 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC094795-1|AAH94795.1| 724|Homo sapiens phosphoinositide-3-kina... 140 6e-33
BC030815-1|AAH30815.1| 454|Homo sapiens phosphoinositide-3-kina... 140 6e-33
AK223613-1|BAD97333.1| 454|Homo sapiens phosphoinositide-3-kina... 140 6e-33
AF279367-1|AAO15359.1| 424|Homo sapiens phosphoinositide 3-kina... 140 6e-33
X80907-1|CAA56868.1| 728|Homo sapiens p85 beta subunit of phosp... 139 1e-32
BC090249-1|AAH90249.1| 728|Homo sapiens phosphoinositide-3-kina... 139 1e-32
BC070082-1|AAH70082.1| 728|Homo sapiens phosphoinositide-3-kina... 139 1e-32
BC032647-1|AAH32647.1| 481|Homo sapiens PIK3R2 protein protein. 139 1e-32
AC007192-2|AAD22671.1| 728|Homo sapiens P85B_HUMAN protein. 139 1e-32
D88532-1|BAA13636.1| 461|Homo sapiens p55pik protein. 138 2e-32
BX537388-1|CAD97630.1| 494|Homo sapiens hypothetical protein pr... 138 2e-32
BC021622-1|AAH21622.1| 461|Homo sapiens phosphoinositide-3-kina... 138 2e-32
BC005381-1|AAH05381.1| 283|Homo sapiens Unknown (protein for IM... 138 2e-32
AL358075-3|CAI21703.1| 402|Homo sapiens phosphoinositide-3-kina... 138 2e-32
AL358075-2|CAI21702.1| 461|Homo sapiens phosphoinositide-3-kina... 138 2e-32
AL358075-1|CAI21701.1| 206|Homo sapiens phosphoinositide-3-kina... 138 2e-32
AF028785-1|AAC39696.1| 402|Homo sapiens phosphatidylinositol 3-... 138 2e-32
BC011917-1|AAH11917.2| 388|Homo sapiens PIK3R2 protein protein. 106 9e-23
BC014170-1|AAH14170.2| 324|Homo sapiens PIK3R2 protein protein. 65 4e-10
X83931-1|CAA58783.1| 539|Homo sapiens VAV protein. 59 2e-08
BC013361-1|AAH13361.2| 790|Homo sapiens VAV1 protein protein. 59 2e-08
AF030227-1|AAC25011.1| 845|Homo sapiens vav protein protein. 59 2e-08
BC010399-1|AAH10399.1| 198|Homo sapiens suppressor of cytokine ... 58 3e-08
AF037989-1|AAC34745.1| 198|Homo sapiens STAT-induced STAT inhib... 58 3e-08
AF020590-1|AAC98896.1| 197|Homo sapiens suppressor of cytokine ... 58 3e-08
AB006966-1|BAA22536.1| 198|Homo sapiens CIS2 protein. 58 3e-08
AB004903-1|BAA22429.1| 198|Homo sapiens STAT induced STAT inhib... 58 3e-08
BC020082-1|AAH20082.1| 535|Homo sapiens suppressor of cytokine ... 58 4e-08
AB006968-1|BAA22538.1| 535|Homo sapiens CIS4 protein. 58 4e-08
X14034-1|CAA32194.1| 1252|Homo sapiens protein ( Human mRNA for ... 57 1e-07
M37238-1|AAA60112.1| 1252|Homo sapiens PLC1 protein. 57 1e-07
AY364256-1|AAQ76815.1| 1252|Homo sapiens phospholipase C gamma 2... 57 1e-07
BC018646-1|AAH18646.1| 1265|Homo sapiens PLCG2 protein protein. 56 1e-07
BC014561-1|AAH14561.1| 1265|Homo sapiens PLCG2 protein protein. 56 1e-07
BC011772-1|AAH11772.1| 1265|Homo sapiens PLCG2 protein protein. 56 1e-07
BC007565-1|AAH07565.1| 1265|Homo sapiens PLCG2 protein protein. 56 1e-07
AB208914-1|BAD92151.1| 1278|Homo sapiens 1-phosphatidylinositol-... 56 1e-07
K03218-1|AAA60584.1| 536|Homo sapiens SRC protein. 55 3e-07
BC051270-1|AAH51270.2| 536|Homo sapiens v-src sarcoma (Schmidt-... 55 3e-07
BC011566-1|AAH11566.1| 536|Homo sapiens SRC protein protein. 55 3e-07
AL133293-2|CAC34523.1| 536|Homo sapiens v-src sarcoma (Schmidt-... 55 3e-07
AL133293-1|CAC10573.1| 542|Homo sapiens v-src sarcoma (Schmidt-... 55 3e-07
X16316-1|CAA34383.1| 797|Homo sapiens VAV protein. 55 4e-07
M34667-1|AAA36452.1| 1290|Homo sapiens protein ( Human phospholi... 54 5e-07
DQ297143-1|ABB84466.1| 1291|Homo sapiens phospholipase C, gamma ... 54 5e-07
AL591042-2|CAI14458.1| 753|Homo sapiens vav 3 oncogene protein. 54 5e-07
AL591042-1|CAI14457.1| 847|Homo sapiens vav 3 oncogene protein. 54 5e-07
AL513206-2|CAH73196.1| 753|Homo sapiens vav 3 oncogene protein. 54 5e-07
AL513206-1|CAH73195.1| 847|Homo sapiens vav 3 oncogene protein. 54 5e-07
AL391235-1|CAH72458.1| 847|Homo sapiens vav 3 oncogene protein. 54 5e-07
AL353892-1|CAI21786.1| 847|Homo sapiens vav 3 oncogene protein. 54 5e-07
AL022394-3|CAA18537.1| 1290|Homo sapiens phospholipase C, gamma ... 54 5e-07
AL022394-2|CAM28260.1| 1291|Homo sapiens phospholipase C, gamma ... 54 5e-07
AF118887-1|AAD20349.1| 847|Homo sapiens VAV-3 protein protein. 54 5e-07
AF118886-1|AAD20348.1| 753|Homo sapiens VAV-3 protein beta isof... 54 5e-07
AF067817-1|AAC79695.1| 847|Homo sapiens VAV-3 protein protein. 54 5e-07
AB210028-1|BAE06110.1| 1412|Homo sapiens PLCG1 variant protein p... 54 5e-07
X74765-1|CAB58562.1| 450|Homo sapiens protein tyrosine kinase p... 54 9e-07
X60114-1|CAA42713.1| 450|Homo sapiens put. cytoplasmic tyrosine... 54 9e-07
X59932-1|CAA42556.1| 450|Homo sapiens c-src-kinase protein. 54 9e-07
DQ075211-1|AAY57329.1| 450|Homo sapiens c-src tyrosine kinase p... 54 9e-07
CR541960-1|CAG46758.1| 450|Homo sapiens CSK protein. 54 9e-07
BC106073-1|AAI06074.1| 450|Homo sapiens c-src tyrosine kinase p... 54 9e-07
BC104875-1|AAI04876.1| 450|Homo sapiens c-src tyrosine kinase p... 54 9e-07
BC104847-1|AAI04848.1| 450|Homo sapiens c-src tyrosine kinase p... 54 9e-07
AK223626-1|BAD97346.1| 449|Homo sapiens c-src tyrosine kinase v... 54 9e-07
M19722-1|AAA52451.1| 529|Homo sapiens FGR protein. 51 6e-06
M12724-1|AAA52762.1| 306|Homo sapiens FGR protein. 51 6e-06
BC064382-1|AAH64382.1| 529|Homo sapiens Gardner-Rasheed feline ... 51 6e-06
AL031729-3|CAB62998.1| 529|Homo sapiens Gardner-Rasheed feline ... 51 6e-06
AL031729-2|CAI19617.1| 313|Homo sapiens Gardner-Rasheed feline ... 51 6e-06
X77278-1|CAA54493.1| 507|Homo sapiens HYL tyrosine kinase protein. 50 9e-06
S75164-1|AAC60645.1| 507|Homo sapiens megakaryocyte-associated ... 50 9e-06
L18974-1|AAA16703.1| 527|Homo sapiens tyrosine kinase protein. 50 9e-06
BC003109-1|AAH03109.1| 507|Homo sapiens megakaryocyte-associate... 50 9e-06
BC000114-1|AAH00114.1| 507|Homo sapiens megakaryocyte-associate... 50 9e-06
AC005777-1|AAC62843.1| 507|Homo sapiens MATK_HUMAN protein. 50 9e-06
S71669-1|AAB30995.1| 465|Homo sapiens lsk protein. 50 1e-05
Z97989-4|CAI22300.1| 537|Homo sapiens FYN oncogene related to S... 49 2e-05
M14676-1|AAA36615.1| 537|Homo sapiens protein ( Human src-like ... 49 2e-05
M14333-1|AAC08285.1| 537|Homo sapiens protein ( Homo sapiens c-... 49 2e-05
Z97989-5|CAI22301.1| 534|Homo sapiens FYN oncogene related to S... 48 5e-05
Z46940-6|CAB92528.1| 211|Homo sapiens suppressor of cytokine si... 48 5e-05
U88326-1|AAB62401.1| 211|Homo sapiens suppressor of cytokine si... 48 5e-05
S74774-1|AAB33113.2| 534|Homo sapiens tyrosine kinase p59fyn(T)... 48 5e-05
DQ086801-1|AAY87931.1| 211|Homo sapiens suppressor of cytokine ... 48 5e-05
AF132440-1|AAD27709.1| 211|Homo sapiens suppressor of cytokine ... 48 5e-05
AB005043-1|BAA22431.1| 211|Homo sapiens STAT induced STAT inhib... 48 5e-05
AB000734-1|BAA23521.1| 211|Homo sapiens TIP3 protein. 48 5e-05
AB000676-1|BAA21537.1| 197|Homo sapiens JAB protein. 48 5e-05
BC117210-1|AAI17211.1| 495|Homo sapiens Src homology 2 domain c... 48 6e-05
AL162591-2|CAH72851.1| 495|Homo sapiens Src homology 2 domain c... 48 6e-05
AK074067-1|BAB84893.1| 309|Homo sapiens FLJ00138 protein protein. 48 6e-05
BC128607-1|AAI28608.1| 440|Homo sapiens SOCS7 protein protein. 47 8e-05
AB005216-1|BAA22432.1| 485|Homo sapiens Nck, Ash and phospholip... 47 8e-05
X78549-1|CAA55295.1| 451|Homo sapiens tyrosine kinase protein. 47 1e-04
U61412-1|AAC34935.1| 451|Homo sapiens non-receptor type protein... 47 1e-04
S76992-1|AAB34377.1| 878|Homo sapiens VAV2 protein. 47 1e-04
BX640754-1|CAE45861.1| 801|Homo sapiens hypothetical protein pr... 47 1e-04
BC132967-1|AAI32968.1| 839|Homo sapiens vav 2 guanine nucleotid... 47 1e-04
BC132965-1|AAI32966.1| 839|Homo sapiens vav 2 guanine nucleotid... 47 1e-04
BC128448-1|AAI28449.1| 474|Homo sapiens VAV2 protein protein. 47 1e-04
BC035843-1|AAH35843.1| 451|Homo sapiens PTK6 protein tyrosine k... 47 1e-04
BC033187-1|AAH33187.1| 369|Homo sapiens VAV2 protein protein. 47 1e-04
AL590710-7|CAI12280.1| 839|Homo sapiens vav 2 oncogene protein. 47 1e-04
AL590710-6|CAI12278.1| 868|Homo sapiens vav 2 oncogene protein. 47 1e-04
AL590710-5|CAI12279.1| 878|Homo sapiens vav 2 oncogene protein. 47 1e-04
AL445931-3|CAI13724.1| 839|Homo sapiens vav 2 oncogene protein. 47 1e-04
AL445931-2|CAI13723.1| 868|Homo sapiens vav 2 oncogene protein. 47 1e-04
AL445931-1|CAI13722.1| 878|Homo sapiens vav 2 oncogene protein. 47 1e-04
AL357934-3|CAI15782.1| 839|Homo sapiens vav 2 oncogene protein. 47 1e-04
AL357934-2|CAI15781.1| 868|Homo sapiens vav 2 oncogene protein. 47 1e-04
AL357934-1|CAI15783.1| 878|Homo sapiens vav 2 oncogene protein. 47 1e-04
AL121829-13|CAC15525.1| 451|Homo sapiens PTK6 protein. 47 1e-04
X70766-1|CAA50045.1| 593|Homo sapiens protein-tyrosine phosphat... 46 1e-04
L07527-1|AAA17022.1| 593|Homo sapiens protein-tyrosine phosphat... 46 1e-04
L03535-1|AAA36611.1| 593|Homo sapiens phosphotyrosyl-protein ph... 46 1e-04
D13540-1|BAA02740.2| 593|Homo sapiens protein-tyrosine phosphat... 46 1e-04
BT007106-1|AAP35770.1| 460|Homo sapiens protein tyrosine phosph... 46 1e-04
BC008692-1|AAH08692.1| 460|Homo sapiens PTPN11 protein protein. 46 1e-04
D83532-1|BAA92328.1| 258|Homo sapiens cytokine-inducible SH2-co... 46 2e-04
BC064354-1|AAH64354.1| 258|Homo sapiens cytokine inducible SH2-... 46 2e-04
BC031590-1|AAH31590.1| 258|Homo sapiens cytokine inducible SH2-... 46 2e-04
AF132297-1|AAD28471.2| 258|Homo sapiens cytokine-inducible SH2-... 46 2e-04
AF035947-1|AAF97410.1| 264|Homo sapiens cytokine-inducible inhi... 46 2e-04
AF035946-1|AAQ13420.1| 264|Homo sapiens cytokine-inducible inhi... 46 2e-04
D10656-1|BAA01505.1| 304|Homo sapiens CRK-II protein. 45 3e-04
BT007277-1|AAP35941.1| 304|Homo sapiens v-crk sarcoma virus CT1... 45 3e-04
BC009837-1|AAH09837.1| 204|Homo sapiens v-crk sarcoma virus CT1... 45 3e-04
BC008506-1|AAH08506.1| 304|Homo sapiens v-crk sarcoma virus CT1... 45 3e-04
BC007195-1|AAH07195.1| 380|Homo sapiens NCK adaptor protein 2 p... 45 3e-04
BC001718-1|AAH01718.1| 304|Homo sapiens v-crk sarcoma virus CT1... 45 3e-04
BC000103-1|AAH00103.1| 380|Homo sapiens NCK adaptor protein 2 p... 45 3e-04
AF047487-1|AAC80284.1| 380|Homo sapiens Nck-2 protein. 45 3e-04
AF043119-1|AAC04831.1| 381|Homo sapiens SH2/SH3 adaptor protein... 45 3e-04
AC009505-1|AAY24332.1| 304|Homo sapiens unknown protein. 45 3e-04
D84361-2|BAA12323.1| 474|Homo sapiens p52 isoform of N-Shc prot... 45 4e-04
D84361-1|BAA12322.1| 594|Homo sapiens p64 isoform of N-Shc prot... 45 4e-04
BC032496-1|AAH32496.1| 482|Homo sapiens FYN oncogene related to... 45 4e-04
BC026314-1|AAH26314.1| 594|Homo sapiens SHC (Src homology 2 dom... 45 4e-04
AL583849-1|CAH73120.1| 509|Homo sapiens Src homology 2 domain c... 45 4e-04
AL353150-2|CAI16865.1| 594|Homo sapiens SHC (Src homology 2 dom... 45 4e-04
AL161448-1|CAH73192.1| 509|Homo sapiens Src homology 2 domain c... 45 4e-04
AL160054-4|CAI41366.1| 594|Homo sapiens SHC (Src homology 2 dom... 45 4e-04
AL138752-4|CAI13876.1| 509|Homo sapiens Src homology 2 domain c... 45 4e-04
U22322-1|AAC50116.1| 505|Homo sapiens Rak protein. 44 6e-04
M15990-1|AAA35735.1| 543|Homo sapiens protein ( Human c-yes-1 m... 44 6e-04
BC048960-1|AAH48960.1| 543|Homo sapiens v-yes-1 Yamaguchi sarco... 44 6e-04
X75342-1|CAA53091.1| 596|Homo sapiens Shb protein. 44 7e-04
X17576-1|CAA35599.1| 377|Homo sapiens protein ( Human melanoma ... 44 7e-04
U34379-1|AAB60412.1| 527|Homo sapiens tyrosine kinase protein. 44 7e-04
U00803-1|AAA18284.1| 505|Homo sapiens SRC-like tyrosine kinase ... 44 7e-04
L27071-1|AAA74557.1| 527|Homo sapiens tyrosine kinase protein. 44 7e-04
BC012916-1|AAH12916.1| 505|Homo sapiens fyn-related kinase prot... 44 7e-04
BC006403-1|AAH06403.1| 377|Homo sapiens NCK adaptor protein 1 p... 44 7e-04
AL357141-2|CAI16469.1| 505|Homo sapiens fyn-related kinase prot... 44 7e-04
AL121963-8|CAB87592.2| 505|Homo sapiens fyn-related kinase prot... 44 7e-04
U44403-1|AAC27662.1| 276|Homo sapiens Src-like adapter protein ... 44 0.001
U30473-1|AAC50357.1| 276|Homo sapiens src-like adapter protein ... 44 0.001
D89077-1|BAA13758.1| 276|Homo sapiens Src-like adapter protein ... 44 0.001
CR536537-1|CAG38774.1| 276|Homo sapiens SLA protein. 44 0.001
BC007586-1|AAH07586.1| 233|Homo sapiens SHF protein protein. 44 0.001
BC007042-1|AAH07042.1| 276|Homo sapiens Src-like-adaptor protein. 44 0.001
AB110420-1|BAC76765.1| 428|Homo sapiens MIST protein. 43 0.001
U20158-1|AAC50135.1| 533|Homo sapiens SLP-76 protein. 43 0.002
BT007273-1|AAP35937.1| 533|Homo sapiens lymphocyte cytosolic pr... 43 0.002
BC016618-1|AAH16618.1| 533|Homo sapiens lymphocyte cytosolic pr... 43 0.002
Z97989-6|CAI22299.1| 485|Homo sapiens FYN oncogene related to S... 42 0.002
S65186-1|AAB28072.2| 620|Homo sapiens EMT protein. 42 0.002
L10717-1|AAA36748.1| 620|Homo sapiens tyrosine kinase protein. 42 0.002
D13720-1|BAA02873.1| 620|Homo sapiens ITK protein. 42 0.002
BT019994-1|AAV38797.1| 276|Homo sapiens Src-like-adaptor protein. 42 0.002
BC109078-1|AAI09079.1| 620|Homo sapiens IL2-inducible T-cell ki... 42 0.002
BC109077-1|AAI09078.1| 620|Homo sapiens IL2-inducible T-cell ki... 42 0.002
BC033907-1|AAH33907.1| 630|Homo sapiens SHC (Src homology 2 dom... 42 0.002
AY464565-1|AAR19363.1| 630|Homo sapiens rai-like protein RaLP p... 42 0.002
AY358250-1|AAQ88617.1| 387|Homo sapiens LPAL6438 protein. 42 0.002
AB209622-1|BAD92859.1| 376|Homo sapiens IL2-inducible T-cell ki... 42 0.002
X62852-1|CAA44664.1| 160|Homo sapiens ash protein protein. 42 0.003
M96995-1|AAA58448.1| 217|Homo sapiens epidermal growth factor r... 42 0.003
CR541942-1|CAG46740.1| 217|Homo sapiens GRB2 protein. 42 0.003
CR450363-1|CAG29359.1| 217|Homo sapiens GRB2 protein. 42 0.003
BC000631-1|AAH00631.1| 217|Homo sapiens growth factor receptor-... 42 0.003
AF498925-1|AAM21073.1| 217|Homo sapiens growth factor receptor-... 42 0.003
AF063618-1|AAC72075.1| 217|Homo sapiens growth factor receptor-... 42 0.003
AJ012793-1|CAB42642.1| 576|Homo sapiens lymphocyte adaptor prot... 42 0.004
AF055581-1|AAC71695.1| 575|Homo sapiens adaptor protein Lnk pro... 42 0.004
AB208911-1|BAD92148.1| 439|Homo sapiens lymphocyte adaptor prot... 42 0.004
AB032369-1|BAA96241.1| 376|Homo sapiens MIST protein. 42 0.004
X59656-1|CAA42199.1| 303|Homo sapiens CRKL protein. 41 0.005
M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein. 41 0.005
CR541694-1|CAG46495.1| 225|Homo sapiens SOCS3 protein. 41 0.005
CR536497-1|CAG38736.1| 225|Homo sapiens SOCS3 protein. 41 0.005
CR456423-1|CAG30309.1| 303|Homo sapiens CRKL protein. 41 0.005
BT019544-1|AAV38351.1| 225|Homo sapiens suppressor of cytokine ... 41 0.005
BC060858-1|AAH60858.1| 225|Homo sapiens suppressor of cytokine ... 41 0.005
BC043500-1|AAH43500.1| 303|Homo sapiens v-crk sarcoma virus CT1... 41 0.005
BC012924-1|AAH12924.1| 280|Homo sapiens DAPP1 protein protein. 41 0.005
AF186022-1|AAF14578.1| 280|Homo sapiens B lymphocyte adapter pr... 41 0.005
AF178987-1|AAF44351.1| 280|Homo sapiens protein-tyrosine phosph... 41 0.005
AF163254-1|AAD49697.1| 280|Homo sapiens adaptor protein DAPP1 p... 41 0.005
AF159854-1|AAD42231.1| 225|Homo sapiens cytokine signaling supp... 41 0.005
AB006967-1|BAA22537.1| 225|Homo sapiens CIS3 protein. 41 0.005
X83107-1|CAA58169.1| 675|Homo sapiens bmx protein. 40 0.009
BC016652-1|AAH16652.1| 675|Homo sapiens BMX non-receptor tyrosi... 40 0.009
AL731544-3|CAI14998.1| 431|Homo sapiens novel SH2 domain-contai... 40 0.009
AF045459-1|AAC08966.1| 697|Homo sapiens Etk/Bmx cytosolic tyros... 40 0.009
AM491363-1|CAM33013.1| 498|Homo sapiens bcr-abl1 e19a2 chimeric... 40 0.012
AL353150-1|CAI16864.1| 105|Homo sapiens SHC (Src homology 2 dom... 40 0.012
AM491359-1|CAM33009.1| 235|Homo sapiens bcr-abl1 e13a3 chimeric... 40 0.016
X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRN... 39 0.021
U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene tyrosine-p... 39 0.021
U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene tyrosine-p... 39 0.021
M35296-1|AAA35553.1| 1182|Homo sapiens protein ( Human tyrosine ... 39 0.021
DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine le... 39 0.021
DQ009672-1|AAY16984.1| 1182|Homo sapiens v-abl Abelson murine le... 39 0.021
BX538317-1|CAD98092.1| 1092|Homo sapiens hypothetical protein pr... 39 0.021
BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine le... 39 0.021
BC065912-1|AAH65912.1| 1167|Homo sapiens ABL2 protein protein. 39 0.021
AM491362-1|CAM33012.1| 585|Homo sapiens bcr-abl1 e6a2 chimeric ... 39 0.021
AM491361-1|CAM33011.1| 313|Homo sapiens bcr-abl1 e1a3 chimeric ... 39 0.021
AM491360-1|CAM33010.1| 260|Homo sapiens bcr-abl1 e14a3 chimeric... 39 0.021
AL512326-6|CAI13570.1| 1182|Homo sapiens v-abl Abelson murine le... 39 0.021
AL512326-2|CAI13566.1| 1064|Homo sapiens v-abl Abelson murine le... 39 0.021
AL359179-2|CAI15585.1| 1182|Homo sapiens v-abl Abelson murine le... 39 0.021
AL359179-1|CAI15584.1| 1064|Homo sapiens v-abl Abelson murine le... 39 0.021
AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine l... 39 0.021
AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine le... 39 0.021
AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine le... 39 0.021
AL139132-5|CAH70925.1| 1182|Homo sapiens v-abl Abelson murine le... 39 0.021
AL139132-1|CAH70921.1| 1064|Homo sapiens v-abl Abelson murine le... 39 0.021
AJ131467-1|CAA10377.1| 307|Homo sapiens BCR/ABL chimeric fusion... 39 0.021
AJ131466-1|CAA10376.1| 332|Homo sapiens BCR/ABL (major breakpoi... 39 0.021
AF113911-1|AAD04633.1| 359|Homo sapiens BCR-ABL minor breakpoin... 39 0.021
AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine le... 39 0.021
AB004904-1|BAA22430.1| 225|Homo sapiens STAT induced STAT inhib... 39 0.021
X58957-1|CAA41728.1| 659|Homo sapiens agammaglobulinaemia tyros... 39 0.028
U78027-4|AAB64205.1| 659|Homo sapiens Bruton's tyrosine kinase ... 39 0.028
U10087-1|AAB60639.1| 659|Homo sapiens Bruton agammaglobulinemia... 39 0.028
M79321-1|AAB50019.1| 491|Homo sapiens Lyn B protein protein. 39 0.028
M16038-1|AAA59540.1| 512|Homo sapiens LYN protein. 39 0.028
L31572-1|AAA61479.1| 659|Homo sapiens Bruton agammaglobulinemia... 39 0.028
BC126458-1|AAI26459.1| 512|Homo sapiens LYN protein protein. 39 0.028
BC126456-1|AAI26457.1| 512|Homo sapiens LYN protein protein. 39 0.028
BC109080-1|AAI09081.1| 659|Homo sapiens Bruton agammaglobulinem... 39 0.028
BC109079-1|AAI09080.1| 659|Homo sapiens Bruton agammaglobulinem... 39 0.028
BC075002-1|AAH75002.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 39 0.028
BC075001-1|AAH75001.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 39 0.028
BC068551-1|AAH68551.1| 582|Homo sapiens LYN protein protein. 39 0.028
BC059394-1|AAH59394.1| 582|Homo sapiens LYN protein protein. 39 0.028
AL035422-3|CAB55876.1| 659|Homo sapiens Bruton agammaglobulinem... 39 0.028
Z22641-1|CAA80354.1| 459|Homo sapiens a2-chimaerin protein. 38 0.065
BC011393-1|AAH11393.1| 459|Homo sapiens chimerin (chimaerin) 1 ... 38 0.065
AC020596-1|AAY14940.1| 176|Homo sapiens unknown protein. 38 0.065
BC032862-1|AAH32862.1| 536|Homo sapiens SOCS5 protein protein. 37 0.085
AF073958-1|AAD40484.1| 536|Homo sapiens cytokine-inducible SH2 ... 37 0.085
AC020604-1|AAY24289.1| 536|Homo sapiens unknown protein. 37 0.085
AB014571-1|BAA31646.2| 537|Homo sapiens KIAA0671 protein protein. 37 0.085
AY190323-1|AAO41715.1| 298|Homo sapiens SH2A protein. 36 0.15
AL035422-4|CAI42359.1| 483|Homo sapiens Bruton agammaglobulinem... 36 0.15
Y14385-1|CAA74743.1| 1258|Homo sapiens inositol polyphosphate 5-... 36 0.20
U28926-1|AAA86528.1| 468|Homo sapiens beta2-chimaerin protein. 36 0.20
U07223-1|AAA16836.1| 466|Homo sapiens beta2-chimaerin protein. 36 0.20
L29126-1|AAA19191.1| 466|Homo sapiens beta2-chimaerin protein. 36 0.20
BC112155-1|AAI12156.1| 468|Homo sapiens chimerin (chimaerin) 2 ... 36 0.20
BC082982-1|AAH82982.1| 454|Homo sapiens SH2D4A protein protein. 36 0.20
BC018906-1|AAH18906.1| 456|Homo sapiens B-cell linker protein. 36 0.20
BC014525-1|AAH14525.2| 338|Homo sapiens SH2D4A protein protein. 36 0.20
AM180334-1|CAJ55328.1| 433|Homo sapiens B-cell linker protein p... 36 0.20
AM180333-1|CAJ55327.1| 433|Homo sapiens B-cell linker protein p... 36 0.20
AK024799-1|BAB15010.1| 454|Homo sapiens protein ( Homo sapiens ... 36 0.20
AK024620-1|BAB14935.1| 272|Homo sapiens protein ( Homo sapiens ... 36 0.20
AF180756-2|AAF20383.1| 433|Homo sapiens B cell linker protein B... 36 0.20
AF180756-1|AAF20382.1| 456|Homo sapiens B cell linker protein B... 36 0.20
AF068181-1|AAC39937.1| 433|Homo sapiens B cell linker protein B... 36 0.20
AF068180-1|AAC39936.1| 456|Homo sapiens B cell linker protein B... 36 0.20
AC004417-1|AAC06177.1| 175|Homo sapiens unknown protein. 36 0.20
U52518-1|AAC50541.1| 217|Homo sapiens Grb2-related adaptor prot... 36 0.26
CR541966-1|CAG46764.1| 217|Homo sapiens GRAP protein. 36 0.26
CR541941-1|CAG46739.1| 217|Homo sapiens GRAP protein. 36 0.26
BT019981-1|AAV38784.1| 217|Homo sapiens GRB2-related adaptor pr... 36 0.26
BC063035-1|AAH63035.1| 217|Homo sapiens GRB2-related adaptor pr... 36 0.26
BC035856-1|AAH35856.1| 217|Homo sapiens GRB2-related adaptor pr... 36 0.26
AF417489-1|AAN32667.1| 1445|Homo sapiens tensin 3 protein. 36 0.26
AF378756-1|AAL11993.1| 1205|Homo sapiens tumor endothelial marke... 36 0.26
AC073341-1|AAQ96841.1| 1205|Homo sapiens unknown protein. 36 0.26
AB062750-1|BAB60681.1| 627|Homo sapiens thyroid specific PTB do... 36 0.26
AL121829-14|CAC15526.1| 488|Homo sapiens protein ( ne kinase, t... 35 0.34
AJ865079-1|CAI23831.1| 516|Homo sapiens proto-oncogene tyrosine... 35 0.46
X98429-1|CAA67071.1| 1188|Homo sapiens inositol polyphosphate 5-... 34 0.60
X14055-1|CAA32211.1| 509|Homo sapiens protein ( Human lymphocyt... 34 0.60
X13529-1|CAA31884.1| 509|Homo sapiens protein ( Human lck mRNA ... 34 0.60
U57650-1|AAB53573.1| 1188|Homo sapiens SH2-containing inositol 5... 34 0.60
U53470-1|AAD00081.1| 1189|Homo sapiens signaling inositol polyph... 34 0.60
U50041-1|AAC50454.1| 1179|Homo sapiens signaling inositol polyph... 34 0.60
U23852-1|AAC50287.1| 363|Homo sapiens p56lck protein. 34 0.60
U07236-1|AAA18225.1| 512|Homo sapiens lymphocyte-specific prote... 34 0.60
M36881-1|AAA59502.1| 509|Homo sapiens lymphocyte-specific prote... 34 0.60
M16592-1|AAA52644.1| 505|Homo sapiens HCK protein. 34 0.60
M16591-1|AAA52643.1| 505|Homo sapiens HCK protein. 34 0.60
BC114463-1|AAI14464.2| 526|Homo sapiens hemopoietic cell kinase... 34 0.60
BC113854-1|AAI13855.2| 504|Homo sapiens HCK protein protein. 34 0.60
BC113582-1|AAI13583.1| 1188|Homo sapiens inositol polyphosphate-... 34 0.60
BC113580-1|AAI13581.1| 1188|Homo sapiens inositol polyphosphate-... 34 0.60
BC108931-1|AAI08932.2| 526|Homo sapiens hemopoietic cell kinase... 34 0.60
BC108930-1|AAI08931.2| 526|Homo sapiens hemopoietic cell kinase... 34 0.60
BC099920-1|AAH99920.1| 1188|Homo sapiens inositol polyphosphate-... 34 0.60
BC094847-1|AAH94847.2| 526|Homo sapiens hemopoietic cell kinase... 34 0.60
BC014435-1|AAH14435.2| 526|Homo sapiens hemopoietic cell kinase... 34 0.60
BC013200-1|AAH13200.1| 539|Homo sapiens LCK protein protein. 34 0.60
AL353092-2|CAI19694.1| 505|Homo sapiens hemopoietic cell kinase... 34 0.60
AL353092-1|CAI19695.1| 504|Homo sapiens hemopoietic cell kinase... 34 0.60
AL121991-3|CAI22320.1| 496|Homo sapiens lymphocyte-specific pro... 34 0.60
AL121991-2|CAI22321.1| 526|Homo sapiens lymphocyte-specific pro... 34 0.60
AL049539-2|CAI22966.1| 505|Homo sapiens hemopoietic cell kinase... 34 0.60
AL049539-1|CAI22967.1| 504|Homo sapiens hemopoietic cell kinase... 34 0.60
AF228313-1|AAF34794.1| 496|Homo sapiens tyrosine kinase LCK pro... 34 0.60
BC025237-1|AAH25237.1| 352|Homo sapiens hematopoietic SH2 domai... 34 0.80
AY319652-1|AAQ81285.1| 352|Homo sapiens ALX protein. 34 0.80
AK027792-1|BAB55372.1| 352|Homo sapiens protein ( Homo sapiens ... 34 0.80
X05027-1|CAA28691.1| 507|Homo sapiens protein ( Human T cell-sp... 33 1.4
BC060790-1|AAH60790.1| 440|Homo sapiens suppressor of cytokine ... 33 1.4
AF424815-1|AAL60517.1| 440|Homo sapiens SH2 domain containing S... 33 1.4
AB000520-1|BAA22514.1| 632|Homo sapiens APS protein. 33 1.4
AL390078-1|CAB98202.1| 247|Homo sapiens similar to (NP_033194.1... 33 1.8
AK055673-1|BAB70981.1| 340|Homo sapiens protein ( Homo sapiens ... 33 1.8
U13433-1|AAC51347.1| 657|Homo sapiens Bruton's agammaglobulinem... 32 2.4
M27454-1|AAA35679.1| 177|Homo sapiens tyrosine kinase protein. 32 2.4
BC032365-1|AAH32365.1| 860|Homo sapiens SH2 domain containing 3... 32 2.4
BC027962-1|AAH27962.1| 703|Homo sapiens SH2D3C protein protein. 32 2.4
BC018706-1|AAH18706.1| 480|Homo sapiens TNS4 protein protein. 32 2.4
BC007206-1|AAH07206.1| 340|Homo sapiens Src homology 2 domain c... 32 2.4
AY358440-1|AAQ89948.1| 703|Homo sapiens NSP3 protein. 32 2.4
AY358089-1|AAQ88456.1| 688|Homo sapiens NSP3 protein. 32 2.4
AL162586-7|CAI39766.1| 860|Homo sapiens SH2 domain containing 3... 32 2.4
AL162586-4|CAI39763.1| 703|Homo sapiens SH2 domain containing 3... 32 2.4
AL162586-3|CAI39762.1| 324|Homo sapiens SH2 domain containing 3... 32 2.4
AL162586-2|CAI39761.1| 702|Homo sapiens SH2 domain containing 3... 32 2.4
AL162586-1|CAI39760.1| 196|Homo sapiens SH2 domain containing 3... 32 2.4
AL162426-7|CAI41182.1| 860|Homo sapiens SH2 domain containing 3... 32 2.4
AL162426-4|CAI41179.1| 703|Homo sapiens SH2 domain containing 3... 32 2.4
AL162426-3|CAI41178.1| 324|Homo sapiens SH2 domain containing 3... 32 2.4
AL162426-2|CAI41177.1| 702|Homo sapiens SH2 domain containing 3... 32 2.4
AL162426-1|CAI41176.1| 196|Homo sapiens SH2 domain containing 3... 32 2.4
AK027856-1|BAB55413.1| 480|Homo sapiens protein ( Homo sapiens ... 32 2.4
AF417488-1|AAN32666.1| 715|Homo sapiens C-terminal tensin-like ... 32 2.4
AF124251-1|AAD28246.1| 703|Homo sapiens SH2-containing protein ... 32 2.4
BC150259-1|AAI50260.1| 1409|Homo sapiens tensin like C1 domain c... 32 3.2
BC142712-1|AAI42713.1| 1409|Homo sapiens tensin like C1 domain c... 32 3.2
BC142668-1|AAI42669.1| 1409|Homo sapiens tensin like C1 domain c... 32 3.2
BC129829-1|AAI29830.1| 1285|Homo sapiens TENC1 protein protein. 32 3.2
BC129828-1|AAI29829.1| 1285|Homo sapiens TENC1 protein protein. 32 3.2
BC110854-1|AAI10855.1| 1291|Homo sapiens TENC1 protein protein. 32 3.2
AF518729-1|AAM74225.1| 1409|Homo sapiens C1 domain-containing ph... 32 3.2
AF518728-1|AAN03866.1| 1419|Homo sapiens C1 domain-containing ph... 32 3.2
AF417490-1|AAL14641.1| 1285|Homo sapiens tensin2 protein. 32 3.2
AB028998-1|BAA83027.2| 1505|Homo sapiens KIAA1075 protein protein. 32 3.2
BC126910-1|AAI26911.2| 1768|Homo sapiens TNS1 protein protein. 31 4.2
BC116188-1|AAI16189.1| 1713|Homo sapiens TNS1 protein protein. 31 4.2
BC116187-1|AAI16188.1| 1721|Homo sapiens TNS1 protein protein. 31 4.2
BC014042-1|AAH14042.1| 438|Homo sapiens TNS1 protein protein. 31 4.2
AF225896-1|AAG33700.1| 1735|Homo sapiens tensin protein. 31 4.2
AC009469-1|AAX88952.1| 1735|Homo sapiens unknown protein. 31 4.2
AB209238-1|BAD92475.1| 873|Homo sapiens tensin variant protein. 31 4.2
D29767-1|BAA06171.1| 631|Homo sapiens Tec protein-tyrosine kina... 31 5.6
BC101713-1|AAI01714.1| 631|Homo sapiens tec protein tyrosine ki... 31 5.6
BC101711-1|AAI01712.1| 631|Homo sapiens tec protein tyrosine ki... 31 5.6
BC053878-1|AAH53878.1| 619|Homo sapiens zeta-chain (TCR) associ... 31 5.6
BC039039-1|AAH39039.1| 493|Homo sapiens ZAP70 protein protein. 31 5.6
AC016699-1|AAX93187.1| 493|Homo sapiens unknown protein. 31 5.6
BC067117-1|AAH67117.1| 380|Homo sapiens SH2D4A protein protein. 31 7.4
BC066658-1|AAH66658.1| 344|Homo sapiens centromere protein L pr... 31 7.4
BC042041-1|AAH42041.1| 261|Homo sapiens Src-like-adaptor 2 prot... 31 7.4
BC033154-1|AAH33154.1| 390|Homo sapiens CENPL protein protein. 31 7.4
BC007071-1|AAH07071.1| 344|Homo sapiens centromere protein L pr... 31 7.4
AL109921-3|CAI20378.1| 390|Homo sapiens novel protein protein. 31 7.4
AL109921-2|CAI20379.1| 344|Homo sapiens novel protein protein. 31 7.4
AL050318-2|CAI23504.1| 261|Homo sapiens Src-like-adaptor 2 prot... 31 7.4
AL031662-2|CAI21397.1| 261|Homo sapiens Src-like-adaptor 2 prot... 31 7.4
AK025645-1|BAB15201.1| 261|Homo sapiens protein ( Homo sapiens ... 31 7.4
AF326353-1|AAL29204.1| 261|Homo sapiens Src-like adapter protei... 31 7.4
AF290985-1|AAL38197.1| 261|Homo sapiens Src-like adaptor protei... 31 7.4
>BC094795-1|AAH94795.1| 724|Homo sapiens phosphoinositide-3-kinase,
regulatory subunit 1 (p85 alpha) protein.
Length = 724
Score = 140 bits (339), Expect = 6e-33
Identities = 65/102 (63%), Positives = 79/102 (77%), Gaps = 1/102 (0%)
Frame = +1
Query: 334 SLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSG-YTLTVRKGGANKLIKIYHH 510
SL+ AEWYWGDI+R+E NEKLRDT DGTFLVR+AS K G YTLT+RKGG NKLIKI+H
Sbjct: 327 SLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHR 386
Query: 511 EGRYGFREPFEFKSVVDLVCYYSEYSLATCNSSLDIKLLXSI 636
+G+YGF +P F SVV+L+ +Y SLA N LD+KLL +
Sbjct: 387 DGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPV 428
Score = 64.5 bits (150), Expect = 5e-10
Identities = 43/130 (33%), Positives = 65/130 (50%), Gaps = 1/130 (0%)
Frame = +1
Query: 238 VKQRKLDNYTAPSSPDDEIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKLRDTRDGT 417
V+Q+KL+ + + +D+ + + + P H + W G R++A LR RDGT
Sbjct: 589 VRQKKLNEWLGNENTEDQYSL-VEDDEDLPHH--DEKTWNVGSSNRNKAENLLRGKRDGT 645
Query: 418 FLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFE-FKSVVDLVCYYSEYSLA 594
FLVR S+K Y +V G K I YGF EP+ + S+ +LV +Y SL
Sbjct: 646 FLVRE-SSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLV 704
Query: 595 TCNSSLDIKL 624
N SL++ L
Sbjct: 705 QHNDSLNVTL 714
Score = 33.1 bits (72), Expect = 1.4
Identities = 13/35 (37%), Positives = 22/35 (62%)
Frame = +2
Query: 758 KYTRLXEEVTLKRQALXAFREAVKMCEDPLNYXEK 862
+YTR +E+ +KR A+ AF E +K+ E+ E+
Sbjct: 469 EYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQER 503
>BC030815-1|AAH30815.1| 454|Homo sapiens phosphoinositide-3-kinase,
regulatory subunit 1 (p85 alpha) protein.
Length = 454
Score = 140 bits (339), Expect = 6e-33
Identities = 65/102 (63%), Positives = 79/102 (77%), Gaps = 1/102 (0%)
Frame = +1
Query: 334 SLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSG-YTLTVRKGGANKLIKIYHH 510
SL+ AEWYWGDI+R+E NEKLRDT DGTFLVR+AS K G YTLT+RKGG NKLIKI+H
Sbjct: 57 SLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHR 116
Query: 511 EGRYGFREPFEFKSVVDLVCYYSEYSLATCNSSLDIKLLXSI 636
+G+YGF +P F SVV+L+ +Y SLA N LD+KLL +
Sbjct: 117 DGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPV 158
Score = 64.5 bits (150), Expect = 5e-10
Identities = 43/130 (33%), Positives = 65/130 (50%), Gaps = 1/130 (0%)
Frame = +1
Query: 238 VKQRKLDNYTAPSSPDDEIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKLRDTRDGT 417
V+Q+KL+ + + +D+ + + + P H + W G R++A LR RDGT
Sbjct: 319 VRQKKLNEWLGNENTEDQYSL-VEDDEDLPHH--DEKTWNVGSSNRNKAENLLRGKRDGT 375
Query: 418 FLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFE-FKSVVDLVCYYSEYSLA 594
FLVR S+K Y +V G K I YGF EP+ + S+ +LV +Y SL
Sbjct: 376 FLVRE-SSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLV 434
Query: 595 TCNSSLDIKL 624
N SL++ L
Sbjct: 435 QHNDSLNVTL 444
Score = 33.1 bits (72), Expect = 1.4
Identities = 13/35 (37%), Positives = 22/35 (62%)
Frame = +2
Query: 758 KYTRLXEEVTLKRQALXAFREAVKMCEDPLNYXEK 862
+YTR +E+ +KR A+ AF E +K+ E+ E+
Sbjct: 199 EYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQER 233
>AK223613-1|BAD97333.1| 454|Homo sapiens phosphoinositide-3-kinase,
regulatory subunit, polypeptide 1 isoform 2 variant
protein.
Length = 454
Score = 140 bits (339), Expect = 6e-33
Identities = 65/102 (63%), Positives = 79/102 (77%), Gaps = 1/102 (0%)
Frame = +1
Query: 334 SLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSG-YTLTVRKGGANKLIKIYHH 510
SL+ AEWYWGDI+R+E NEKLRDT DGTFLVR+AS K G YTLT+RKGG NKLIKI+H
Sbjct: 57 SLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHR 116
Query: 511 EGRYGFREPFEFKSVVDLVCYYSEYSLATCNSSLDIKLLXSI 636
+G+YGF +P F SVV+L+ +Y SLA N LD+KLL +
Sbjct: 117 DGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPV 158
Score = 64.5 bits (150), Expect = 5e-10
Identities = 43/130 (33%), Positives = 65/130 (50%), Gaps = 1/130 (0%)
Frame = +1
Query: 238 VKQRKLDNYTAPSSPDDEIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKLRDTRDGT 417
V+Q+KL+ + + +D+ + + + P H + W G R++A LR RDGT
Sbjct: 319 VRQKKLNEWLGNENTEDQYSL-VEDDEDLPHH--DEKTWNVGSSNRNKAENLLRGKRDGT 375
Query: 418 FLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFE-FKSVVDLVCYYSEYSLA 594
FLVR S+K Y +V G K I YGF EP+ + S+ +LV +Y SL
Sbjct: 376 FLVRE-SSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLV 434
Query: 595 TCNSSLDIKL 624
N SL++ L
Sbjct: 435 QHNDSLNVTL 444
Score = 33.1 bits (72), Expect = 1.4
Identities = 13/35 (37%), Positives = 22/35 (62%)
Frame = +2
Query: 758 KYTRLXEEVTLKRQALXAFREAVKMCEDPLNYXEK 862
+YTR +E+ +KR A+ AF E +K+ E+ E+
Sbjct: 199 EYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQER 233
>AF279367-1|AAO15359.1| 424|Homo sapiens phosphoinositide 3-kinase
p85 subunit splicing variant p46 protein.
Length = 424
Score = 140 bits (339), Expect = 6e-33
Identities = 65/102 (63%), Positives = 79/102 (77%), Gaps = 1/102 (0%)
Frame = +1
Query: 334 SLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSG-YTLTVRKGGANKLIKIYHH 510
SL+ AEWYWGDI+R+E NEKLRDT DGTFLVR+AS K G YTLT+RKGG NKLIKI+H
Sbjct: 27 SLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHR 86
Query: 511 EGRYGFREPFEFKSVVDLVCYYSEYSLATCNSSLDIKLLXSI 636
+G+YGF +P F SVV+L+ +Y SLA N LD+KLL +
Sbjct: 87 DGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPV 128
Score = 64.5 bits (150), Expect = 5e-10
Identities = 43/130 (33%), Positives = 65/130 (50%), Gaps = 1/130 (0%)
Frame = +1
Query: 238 VKQRKLDNYTAPSSPDDEIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKLRDTRDGT 417
V+Q+KL+ + + +D+ + + + P H + W G R++A LR RDGT
Sbjct: 289 VRQKKLNEWLGNENTEDQYSL-VEDDEDLPHH--DEKTWNVGSSNRNKAENLLRGKRDGT 345
Query: 418 FLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFE-FKSVVDLVCYYSEYSLA 594
FLVR S+K Y +V G K I YGF EP+ + S+ +LV +Y SL
Sbjct: 346 FLVRE-SSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLV 404
Query: 595 TCNSSLDIKL 624
N SL++ L
Sbjct: 405 QHNDSLNVTL 414
Score = 33.1 bits (72), Expect = 1.4
Identities = 13/35 (37%), Positives = 22/35 (62%)
Frame = +2
Query: 758 KYTRLXEEVTLKRQALXAFREAVKMCEDPLNYXEK 862
+YTR +E+ +KR A+ AF E +K+ E+ E+
Sbjct: 169 EYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQER 203
>X80907-1|CAA56868.1| 728|Homo sapiens p85 beta subunit of
phosphatidyl-inositol-3-kinase protein.
Length = 728
Score = 139 bits (336), Expect = 1e-32
Identities = 65/102 (63%), Positives = 79/102 (77%), Gaps = 1/102 (0%)
Frame = +1
Query: 334 SLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSG-YTLTVRKGGANKLIKIYHH 510
SL+ AEWYWGDI+R+E NEKLRDT DGTFLVR+AS+K G YTLT+RKGG NKLIK++H
Sbjct: 324 SLQDAEWYWGDISREEVNEKLRDTPDGTFLVRDASSKIQGEYTLTLRKGGNNKLIKVFHR 383
Query: 511 EGRYGFREPFEFKSVVDLVCYYSEYSLATCNSSLDIKLLXSI 636
+G YGF EP F SVVDL+ +Y SLA N+ LD +LL +
Sbjct: 384 DGHYGFSEPLTFCSVVDLINHYRHESLAQYNAKLDTRLLYPV 425
Score = 64.9 bits (151), Expect = 4e-10
Identities = 40/129 (31%), Positives = 62/129 (48%), Gaps = 1/129 (0%)
Frame = +1
Query: 241 KQRKLDNYTAPSSPDDEIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKLRDTRDGTF 420
+Q+K++ + + ++ + P H E WY G I R +A E L RDGTF
Sbjct: 587 RQKKINEWLGIKNETEDQYALMEDEDDLPHH--EERTWYVGKINRTQAEEMLSGKRDGTF 644
Query: 421 LVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFE-FKSVVDLVCYYSEYSLAT 597
L+R +S + Y +V G K IY +GF EP+ + S+ +LV +Y SL
Sbjct: 645 LIRESSQRGC-YACSVVVDGDTKHCVIYRTATGFGFAEPYNLYGSLKELVLHYQHASLVQ 703
Query: 598 CNSSLDIKL 624
N +L + L
Sbjct: 704 HNDALTVTL 712
Score = 32.3 bits (70), Expect = 2.4
Identities = 14/35 (40%), Positives = 22/35 (62%)
Frame = +2
Query: 758 KYTRLXEEVTLKRQALXAFREAVKMCEDPLNYXEK 862
+YTR +E+ +KR A+ AF E +K+ E+ EK
Sbjct: 466 EYTRTSQELQMKRTAIEAFNETIKIFEEQGQTQEK 500
>BC090249-1|AAH90249.1| 728|Homo sapiens phosphoinositide-3-kinase,
regulatory subunit 2 (p85 beta) protein.
Length = 728
Score = 139 bits (336), Expect = 1e-32
Identities = 65/102 (63%), Positives = 79/102 (77%), Gaps = 1/102 (0%)
Frame = +1
Query: 334 SLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSG-YTLTVRKGGANKLIKIYHH 510
SL+ AEWYWGDI+R+E NEKLRDT DGTFLVR+AS+K G YTLT+RKGG NKLIK++H
Sbjct: 324 SLQDAEWYWGDISREEVNEKLRDTPDGTFLVRDASSKIQGEYTLTLRKGGNNKLIKVFHR 383
Query: 511 EGRYGFREPFEFKSVVDLVCYYSEYSLATCNSSLDIKLLXSI 636
+G YGF EP F SVVDL+ +Y SLA N+ LD +LL +
Sbjct: 384 DGHYGFSEPLTFCSVVDLINHYRHESLAQYNAKLDTRLLYPV 425
Score = 64.9 bits (151), Expect = 4e-10
Identities = 40/129 (31%), Positives = 62/129 (48%), Gaps = 1/129 (0%)
Frame = +1
Query: 241 KQRKLDNYTAPSSPDDEIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKLRDTRDGTF 420
+Q+K++ + + ++ + P H E WY G I R +A E L RDGTF
Sbjct: 587 RQKKINEWLGIKNETEDQYALMEDEDDLPHH--EERTWYVGKINRTQAEEMLSGKRDGTF 644
Query: 421 LVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFE-FKSVVDLVCYYSEYSLAT 597
L+R +S + Y +V G K IY +GF EP+ + S+ +LV +Y SL
Sbjct: 645 LIRESSQRGC-YACSVVVDGDTKHCVIYRTATGFGFAEPYNLYGSLKELVLHYQHASLVQ 703
Query: 598 CNSSLDIKL 624
N +L + L
Sbjct: 704 HNDALTVTL 712
Score = 32.3 bits (70), Expect = 2.4
Identities = 14/35 (40%), Positives = 22/35 (62%)
Frame = +2
Query: 758 KYTRLXEEVTLKRQALXAFREAVKMCEDPLNYXEK 862
+YTR +E+ +KR A+ AF E +K+ E+ EK
Sbjct: 466 EYTRTSQELQMKRTAIEAFNETIKIFEEQGQTQEK 500
>BC070082-1|AAH70082.1| 728|Homo sapiens phosphoinositide-3-kinase,
regulatory subunit 2 (p85 beta) protein.
Length = 728
Score = 139 bits (336), Expect = 1e-32
Identities = 65/102 (63%), Positives = 79/102 (77%), Gaps = 1/102 (0%)
Frame = +1
Query: 334 SLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSG-YTLTVRKGGANKLIKIYHH 510
SL+ AEWYWGDI+R+E NEKLRDT DGTFLVR+AS+K G YTLT+RKGG NKLIK++H
Sbjct: 324 SLQDAEWYWGDISREEVNEKLRDTPDGTFLVRDASSKIQGEYTLTLRKGGNNKLIKVFHR 383
Query: 511 EGRYGFREPFEFKSVVDLVCYYSEYSLATCNSSLDIKLLXSI 636
+G YGF EP F SVVDL+ +Y SLA N+ LD +LL +
Sbjct: 384 DGHYGFSEPLTFCSVVDLINHYRHESLAQYNAKLDTRLLYPV 425
Score = 64.9 bits (151), Expect = 4e-10
Identities = 40/129 (31%), Positives = 62/129 (48%), Gaps = 1/129 (0%)
Frame = +1
Query: 241 KQRKLDNYTAPSSPDDEIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKLRDTRDGTF 420
+Q+K++ + + ++ + P H E WY G I R +A E L RDGTF
Sbjct: 587 RQKKINEWLGIKNETEDQYALMEDEDDLPHH--EERTWYVGKINRTQAEEMLSGKRDGTF 644
Query: 421 LVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFE-FKSVVDLVCYYSEYSLAT 597
L+R +S + Y +V G K IY +GF EP+ + S+ +LV +Y SL
Sbjct: 645 LIRESSQRGC-YACSVVVDGDTKHCVIYRTATGFGFAEPYNLYGSLKELVLHYQHASLVQ 703
Query: 598 CNSSLDIKL 624
N +L + L
Sbjct: 704 HNDALTVTL 712
Score = 32.3 bits (70), Expect = 2.4
Identities = 14/35 (40%), Positives = 22/35 (62%)
Frame = +2
Query: 758 KYTRLXEEVTLKRQALXAFREAVKMCEDPLNYXEK 862
+YTR +E+ +KR A+ AF E +K+ E+ EK
Sbjct: 466 EYTRTSQELQMKRTAIEAFNETIKIFEEQGQTQEK 500
>BC032647-1|AAH32647.1| 481|Homo sapiens PIK3R2 protein protein.
Length = 481
Score = 139 bits (336), Expect = 1e-32
Identities = 65/102 (63%), Positives = 79/102 (77%), Gaps = 1/102 (0%)
Frame = +1
Query: 334 SLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSG-YTLTVRKGGANKLIKIYHH 510
SL+ AEWYWGDI+R+E NEKLRDT DGTFLVR+AS+K G YTLT+RKGG NKLIK++H
Sbjct: 324 SLQDAEWYWGDISREEVNEKLRDTPDGTFLVRDASSKIQGEYTLTLRKGGNNKLIKVFHR 383
Query: 511 EGRYGFREPFEFKSVVDLVCYYSEYSLATCNSSLDIKLLXSI 636
+G YGF EP F SVVDL+ +Y SLA N+ LD +LL +
Sbjct: 384 DGHYGFSEPLTFCSVVDLINHYRHESLAQYNAKLDTRLLYPV 425
>AC007192-2|AAD22671.1| 728|Homo sapiens P85B_HUMAN protein.
Length = 728
Score = 139 bits (336), Expect = 1e-32
Identities = 65/102 (63%), Positives = 79/102 (77%), Gaps = 1/102 (0%)
Frame = +1
Query: 334 SLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSG-YTLTVRKGGANKLIKIYHH 510
SL+ AEWYWGDI+R+E NEKLRDT DGTFLVR+AS+K G YTLT+RKGG NKLIK++H
Sbjct: 324 SLQDAEWYWGDISREEVNEKLRDTPDGTFLVRDASSKIQGEYTLTLRKGGNNKLIKVFHR 383
Query: 511 EGRYGFREPFEFKSVVDLVCYYSEYSLATCNSSLDIKLLXSI 636
+G YGF EP F SVVDL+ +Y SLA N+ LD +LL +
Sbjct: 384 DGHYGFSEPLTFCSVVDLINHYRHESLAQYNAKLDTRLLYPV 425
Score = 64.9 bits (151), Expect = 4e-10
Identities = 40/129 (31%), Positives = 62/129 (48%), Gaps = 1/129 (0%)
Frame = +1
Query: 241 KQRKLDNYTAPSSPDDEIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKLRDTRDGTF 420
+Q+K++ + + ++ + P H E WY G I R +A E L RDGTF
Sbjct: 587 RQKKINEWLGIKNETEDQYALMEDEDDLPHH--EERTWYVGKINRTQAEEMLSGKRDGTF 644
Query: 421 LVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFE-FKSVVDLVCYYSEYSLAT 597
L+R +S + Y +V G K IY +GF EP+ + S+ +LV +Y SL
Sbjct: 645 LIRESSQRGC-YACSVVVDGDTKHCVIYRTATGFGFAEPYNLYGSLKELVLHYQHASLVQ 703
Query: 598 CNSSLDIKL 624
N +L + L
Sbjct: 704 HNDALTVTL 712
Score = 32.3 bits (70), Expect = 2.4
Identities = 14/35 (40%), Positives = 22/35 (62%)
Frame = +2
Query: 758 KYTRLXEEVTLKRQALXAFREAVKMCEDPLNYXEK 862
+YTR +E+ +KR A+ AF E +K+ E+ EK
Sbjct: 466 EYTRTSQELQMKRTAIEAFNETIKIFEEQGQTQEK 500
>D88532-1|BAA13636.1| 461|Homo sapiens p55pik protein.
Length = 461
Score = 138 bits (335), Expect = 2e-32
Identities = 66/130 (50%), Positives = 86/130 (66%), Gaps = 1/130 (0%)
Frame = +1
Query: 250 KLDNYTAPSSPDDEIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVR 429
++D P P + + + SL+ AEWYWGDI+R+E N+KLRD DGTFLVR
Sbjct: 31 EMDPPALPPKPPKPMTSAVPNGMKDSSVSLQDAEWYWGDISREEVNDKLRDMPDGTFLVR 90
Query: 430 NASNKDSG-YTLTVRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSLATCNS 606
+AS K G YTLT+RKGG NKLIKIYH +G+YGF +P F SVV+L+ +Y SLA N
Sbjct: 91 DASTKMQGDYTLTLRKGGNNKLIKIYHRDGKYGFSDPLTFNSVVELINHYHHESLAQYNP 150
Query: 607 SLDIKLLXSI 636
LD+KL+ +
Sbjct: 151 KLDVKLMYPV 160
Score = 61.7 bits (143), Expect = 3e-09
Identities = 41/130 (31%), Positives = 65/130 (50%), Gaps = 1/130 (0%)
Frame = +1
Query: 238 VKQRKLDNYTAPSSPDDEIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKLRDTRDGT 417
V+Q++L+ + + D + I ++ H E W+ DI R +A + L DG
Sbjct: 321 VRQKRLNVWLGIKNEDADENYFINEEDENLPHYDEKT-WFVEDINRVQAEDLLYGKPDGA 379
Query: 418 FLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFE-FKSVVDLVCYYSEYSLA 594
FL+R +S K Y +V G K IY YGF EP+ + S+ +LV +Y + SL
Sbjct: 380 FLIRESSKKGC-YACSVVADGEVKHCVIYSTARGYGFAEPYNLYSSLKELVLHYQQTSLV 438
Query: 595 TCNSSLDIKL 624
N SL+++L
Sbjct: 439 QHNDSLNVRL 448
Score = 33.1 bits (72), Expect = 1.4
Identities = 13/35 (37%), Positives = 23/35 (65%)
Frame = +2
Query: 758 KYTRLXEEVTLKRQALXAFREAVKMCEDPLNYXEK 862
+YTR +E+ +KR A+ AF E +K+ E+ + E+
Sbjct: 201 EYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQ 235
>BX537388-1|CAD97630.1| 494|Homo sapiens hypothetical protein
protein.
Length = 494
Score = 138 bits (335), Expect = 2e-32
Identities = 66/130 (50%), Positives = 86/130 (66%), Gaps = 1/130 (0%)
Frame = +1
Query: 250 KLDNYTAPSSPDDEIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVR 429
++D P P + + + SL+ AEWYWGDI+R+E N+KLRD DGTFLVR
Sbjct: 64 EMDPPALPPKPPKPMTSAVPNGMKDSSVSLQDAEWYWGDISREEVNDKLRDMPDGTFLVR 123
Query: 430 NASNKDSG-YTLTVRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSLATCNS 606
+AS K G YTLT+RKGG NKLIKIYH +G+YGF +P F SVV+L+ +Y SLA N
Sbjct: 124 DASTKMQGDYTLTLRKGGNNKLIKIYHRDGKYGFSDPLTFNSVVELINHYHHESLAQYNP 183
Query: 607 SLDIKLLXSI 636
LD+KL+ +
Sbjct: 184 KLDVKLMYPV 193
Score = 61.3 bits (142), Expect = 5e-09
Identities = 41/130 (31%), Positives = 65/130 (50%), Gaps = 1/130 (0%)
Frame = +1
Query: 238 VKQRKLDNYTAPSSPDDEIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKLRDTRDGT 417
V+Q++L+ + + D + I ++ H E W+ DI R +A + L DG
Sbjct: 354 VRQKRLNVWLGIRNEDADENYFINEEDENLPHYDEKT-WFVEDINRVQAEDLLYGKPDGA 412
Query: 418 FLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFE-FKSVVDLVCYYSEYSLA 594
FL+R +S K Y +V G K IY YGF EP+ + S+ +LV +Y + SL
Sbjct: 413 FLIRESSKKGC-YACSVVADGEVKHCVIYSTARGYGFAEPYNLYSSLKELVLHYQQTSLV 471
Query: 595 TCNSSLDIKL 624
N SL+++L
Sbjct: 472 QHNDSLNVRL 481
Score = 33.1 bits (72), Expect = 1.4
Identities = 13/35 (37%), Positives = 23/35 (65%)
Frame = +2
Query: 758 KYTRLXEEVTLKRQALXAFREAVKMCEDPLNYXEK 862
+YTR +E+ +KR A+ AF E +K+ E+ + E+
Sbjct: 234 EYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQ 268
>BC021622-1|AAH21622.1| 461|Homo sapiens phosphoinositide-3-kinase,
regulatory subunit 3 (p55, gamma) protein.
Length = 461
Score = 138 bits (335), Expect = 2e-32
Identities = 66/130 (50%), Positives = 86/130 (66%), Gaps = 1/130 (0%)
Frame = +1
Query: 250 KLDNYTAPSSPDDEIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVR 429
++D P P + + + SL+ AEWYWGDI+R+E N+KLRD DGTFLVR
Sbjct: 31 EMDPPALPPKPPKPMTSAVPNGMKDSSVSLQDAEWYWGDISREEVNDKLRDMPDGTFLVR 90
Query: 430 NASNKDSG-YTLTVRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSLATCNS 606
+AS K G YTLT+RKGG NKLIKIYH +G+YGF +P F SVV+L+ +Y SLA N
Sbjct: 91 DASTKMQGDYTLTLRKGGNNKLIKIYHRDGKYGFSDPLTFNSVVELINHYHHESLAQYNP 150
Query: 607 SLDIKLLXSI 636
LD+KL+ +
Sbjct: 151 KLDVKLMYPV 160
Score = 60.5 bits (140), Expect = 8e-09
Identities = 41/130 (31%), Positives = 64/130 (49%), Gaps = 1/130 (0%)
Frame = +1
Query: 238 VKQRKLDNYTAPSSPDDEIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKLRDTRDGT 417
V+Q++L+ + + D I ++ H E W+ DI R +A + L DG
Sbjct: 321 VRQKRLNVWLGIKNEDAAENYFINEEDENLPHYDEKT-WFVEDINRVQAEDLLYGKPDGA 379
Query: 418 FLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFE-FKSVVDLVCYYSEYSLA 594
FL+R +S K Y +V G K IY YGF EP+ + S+ +LV +Y + SL
Sbjct: 380 FLIRESSKKGC-YACSVVADGEVKHCVIYSTARGYGFAEPYNLYSSLKELVLHYQQTSLV 438
Query: 595 TCNSSLDIKL 624
N SL+++L
Sbjct: 439 QHNDSLNVRL 448
Score = 33.1 bits (72), Expect = 1.4
Identities = 13/35 (37%), Positives = 23/35 (65%)
Frame = +2
Query: 758 KYTRLXEEVTLKRQALXAFREAVKMCEDPLNYXEK 862
+YTR +E+ +KR A+ AF E +K+ E+ + E+
Sbjct: 201 EYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQ 235
>BC005381-1|AAH05381.1| 283|Homo sapiens Unknown (protein for
IMAGE:3935147) protein.
Length = 283
Score = 138 bits (335), Expect = 2e-32
Identities = 66/130 (50%), Positives = 86/130 (66%), Gaps = 1/130 (0%)
Frame = +1
Query: 250 KLDNYTAPSSPDDEIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVR 429
++D P P + + + SL+ AEWYWGDI+R+E N+KLRD DGTFLVR
Sbjct: 31 EMDPPALPPKPPKPMTSAVPNGMKDSSVSLQDAEWYWGDISREEVNDKLRDMPDGTFLVR 90
Query: 430 NASNKDSG-YTLTVRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSLATCNS 606
+AS K G YTLT+RKGG NKLIKIYH +G+YGF +P F SVV+L+ +Y SLA N
Sbjct: 91 DASTKMQGDYTLTLRKGGNNKLIKIYHRDGKYGFSDPLTFNSVVELINHYHHESLAQYNP 150
Query: 607 SLDIKLLXSI 636
LD+KL+ +
Sbjct: 151 KLDVKLMYPV 160
Score = 33.1 bits (72), Expect = 1.4
Identities = 13/35 (37%), Positives = 23/35 (65%)
Frame = +2
Query: 758 KYTRLXEEVTLKRQALXAFREAVKMCEDPLNYXEK 862
+YTR +E+ +KR A+ AF E +K+ E+ + E+
Sbjct: 201 EYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQ 235
>AL358075-3|CAI21703.1| 402|Homo sapiens phosphoinositide-3-kinase,
regulatory subunit 3 (p55, gamma) protein.
Length = 402
Score = 138 bits (335), Expect = 2e-32
Identities = 66/130 (50%), Positives = 86/130 (66%), Gaps = 1/130 (0%)
Frame = +1
Query: 250 KLDNYTAPSSPDDEIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVR 429
++D P P + + + SL+ AEWYWGDI+R+E N+KLRD DGTFLVR
Sbjct: 31 EMDPPALPPKPPKPMTSAVPNGMKDSSVSLQDAEWYWGDISREEVNDKLRDMPDGTFLVR 90
Query: 430 NASNKDSG-YTLTVRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSLATCNS 606
+AS K G YTLT+RKGG NKLIKIYH +G+YGF +P F SVV+L+ +Y SLA N
Sbjct: 91 DASTKMQGDYTLTLRKGGNNKLIKIYHRDGKYGFSDPLTFNSVVELINHYHHESLAQYNP 150
Query: 607 SLDIKLLXSI 636
LD+KL+ +
Sbjct: 151 KLDVKLMYPV 160
Score = 61.7 bits (143), Expect = 3e-09
Identities = 41/130 (31%), Positives = 65/130 (50%), Gaps = 1/130 (0%)
Frame = +1
Query: 238 VKQRKLDNYTAPSSPDDEIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKLRDTRDGT 417
V+Q++L+ + + D + I ++ H E W+ DI R +A + L DG
Sbjct: 262 VRQKRLNVWLGIKNEDADENYFINEEDENLPHYDEKT-WFVEDINRVQAEDLLYGKPDGA 320
Query: 418 FLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFE-FKSVVDLVCYYSEYSLA 594
FL+R +S K Y +V G K IY YGF EP+ + S+ +LV +Y + SL
Sbjct: 321 FLIRESSKKGC-YACSVVADGEVKHCVIYSTARGYGFAEPYNLYSSLKELVLHYQQTSLV 379
Query: 595 TCNSSLDIKL 624
N SL+++L
Sbjct: 380 QHNDSLNVRL 389
Score = 33.1 bits (72), Expect = 1.4
Identities = 13/35 (37%), Positives = 23/35 (65%)
Frame = +2
Query: 758 KYTRLXEEVTLKRQALXAFREAVKMCEDPLNYXEK 862
+YTR +E+ +KR A+ AF E +K+ E+ + E+
Sbjct: 201 EYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQ 235
>AL358075-2|CAI21702.1| 461|Homo sapiens phosphoinositide-3-kinase,
regulatory subunit 3 (p55, gamma) protein.
Length = 461
Score = 138 bits (335), Expect = 2e-32
Identities = 66/130 (50%), Positives = 86/130 (66%), Gaps = 1/130 (0%)
Frame = +1
Query: 250 KLDNYTAPSSPDDEIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVR 429
++D P P + + + SL+ AEWYWGDI+R+E N+KLRD DGTFLVR
Sbjct: 31 EMDPPALPPKPPKPMTSAVPNGMKDSSVSLQDAEWYWGDISREEVNDKLRDMPDGTFLVR 90
Query: 430 NASNKDSG-YTLTVRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSLATCNS 606
+AS K G YTLT+RKGG NKLIKIYH +G+YGF +P F SVV+L+ +Y SLA N
Sbjct: 91 DASTKMQGDYTLTLRKGGNNKLIKIYHRDGKYGFSDPLTFNSVVELINHYHHESLAQYNP 150
Query: 607 SLDIKLLXSI 636
LD+KL+ +
Sbjct: 151 KLDVKLMYPV 160
Score = 61.7 bits (143), Expect = 3e-09
Identities = 41/130 (31%), Positives = 65/130 (50%), Gaps = 1/130 (0%)
Frame = +1
Query: 238 VKQRKLDNYTAPSSPDDEIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKLRDTRDGT 417
V+Q++L+ + + D + I ++ H E W+ DI R +A + L DG
Sbjct: 321 VRQKRLNVWLGIKNEDADENYFINEEDENLPHYDEKT-WFVEDINRVQAEDLLYGKPDGA 379
Query: 418 FLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFE-FKSVVDLVCYYSEYSLA 594
FL+R +S K Y +V G K IY YGF EP+ + S+ +LV +Y + SL
Sbjct: 380 FLIRESSKKGC-YACSVVADGEVKHCVIYSTARGYGFAEPYNLYSSLKELVLHYQQTSLV 438
Query: 595 TCNSSLDIKL 624
N SL+++L
Sbjct: 439 QHNDSLNVRL 448
Score = 33.1 bits (72), Expect = 1.4
Identities = 13/35 (37%), Positives = 23/35 (65%)
Frame = +2
Query: 758 KYTRLXEEVTLKRQALXAFREAVKMCEDPLNYXEK 862
+YTR +E+ +KR A+ AF E +K+ E+ + E+
Sbjct: 201 EYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQ 235
>AL358075-1|CAI21701.1| 206|Homo sapiens phosphoinositide-3-kinase,
regulatory subunit 3 (p55, gamma) protein.
Length = 206
Score = 138 bits (335), Expect = 2e-32
Identities = 66/130 (50%), Positives = 86/130 (66%), Gaps = 1/130 (0%)
Frame = +1
Query: 250 KLDNYTAPSSPDDEIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVR 429
++D P P + + + SL+ AEWYWGDI+R+E N+KLRD DGTFLVR
Sbjct: 31 EMDPPALPPKPPKPMTSAVPNGMKDSSVSLQDAEWYWGDISREEVNDKLRDMPDGTFLVR 90
Query: 430 NASNKDSG-YTLTVRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSLATCNS 606
+AS K G YTLT+RKGG NKLIKIYH +G+YGF +P F SVV+L+ +Y SLA N
Sbjct: 91 DASTKMQGDYTLTLRKGGNNKLIKIYHRDGKYGFSDPLTFNSVVELINHYHHESLAQYNP 150
Query: 607 SLDIKLLXSI 636
LD+KL+ +
Sbjct: 151 KLDVKLMYPV 160
>AF028785-1|AAC39696.1| 402|Homo sapiens phosphatidylinositol
3-kinase p55 gamma regulatory subunit protein.
Length = 402
Score = 138 bits (335), Expect = 2e-32
Identities = 66/130 (50%), Positives = 86/130 (66%), Gaps = 1/130 (0%)
Frame = +1
Query: 250 KLDNYTAPSSPDDEIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVR 429
++D P P + + + SL+ AEWYWGDI+R+E N+KLRD DGTFLVR
Sbjct: 31 EMDPPALPPKPPKPMTSAVPNGMKDSSVSLQDAEWYWGDISREEVNDKLRDMPDGTFLVR 90
Query: 430 NASNKDSG-YTLTVRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSLATCNS 606
+AS K G YTLT+RKGG NKLIKIYH +G+YGF +P F SVV+L+ +Y SLA N
Sbjct: 91 DASTKMQGDYTLTLRKGGNNKLIKIYHRDGKYGFSDPLTFNSVVELINHYHHESLAQYNP 150
Query: 607 SLDIKLLXSI 636
LD+KL+ +
Sbjct: 151 KLDVKLMYPV 160
Score = 61.7 bits (143), Expect = 3e-09
Identities = 41/130 (31%), Positives = 65/130 (50%), Gaps = 1/130 (0%)
Frame = +1
Query: 238 VKQRKLDNYTAPSSPDDEIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKLRDTRDGT 417
V+Q++L+ + + D + I ++ H E W+ DI R +A + L DG
Sbjct: 262 VRQKRLNVWLGIKNEDADENYFINEEDENLPHYDEKT-WFVEDINRVQAEDLLYGKPDGA 320
Query: 418 FLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFE-FKSVVDLVCYYSEYSLA 594
FL+R +S K Y +V G K IY YGF EP+ + S+ +LV +Y + SL
Sbjct: 321 FLIRESSKKGC-YACSVVADGEVKHCVIYSTARGYGFAEPYNLYSSLKELVLHYQQTSLV 379
Query: 595 TCNSSLDIKL 624
N SL+++L
Sbjct: 380 QHNDSLNVRL 389
Score = 33.1 bits (72), Expect = 1.4
Identities = 13/35 (37%), Positives = 23/35 (65%)
Frame = +2
Query: 758 KYTRLXEEVTLKRQALXAFREAVKMCEDPLNYXEK 862
+YTR +E+ +KR A+ AF E +K+ E+ + E+
Sbjct: 201 EYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQ 235
>BC011917-1|AAH11917.2| 388|Homo sapiens PIK3R2 protein protein.
Length = 388
Score = 106 bits (255), Expect = 9e-23
Identities = 52/84 (61%), Positives = 63/84 (75%), Gaps = 1/84 (1%)
Frame = +1
Query: 388 EKLRDTRDGTFLVRNASNKDSG-YTLTVRKGGANKLIKIYHHEGRYGFREPFEFKSVVDL 564
EKLRDT DGTFLVR+AS+K G YTLT+RKGG NKLIK++H +G YGF EP F SVVDL
Sbjct: 2 EKLRDTPDGTFLVRDASSKIQGEYTLTLRKGGNNKLIKVFHRDGHYGFSEPLTFCSVVDL 61
Query: 565 VCYYSEYSLATCNSSLDIKLLXSI 636
+ +Y SLA N+ LD +LL +
Sbjct: 62 INHYRHESLAQYNAKLDTRLLYPV 85
Score = 64.9 bits (151), Expect = 4e-10
Identities = 40/129 (31%), Positives = 62/129 (48%), Gaps = 1/129 (0%)
Frame = +1
Query: 241 KQRKLDNYTAPSSPDDEIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKLRDTRDGTF 420
+Q+K++ + + ++ + P H E WY G I R +A E L RDGTF
Sbjct: 247 RQKKINEWLGIKNETEDQYALMEDEDDLPHH--EERTWYVGKINRTQAEEMLSGKRDGTF 304
Query: 421 LVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFE-FKSVVDLVCYYSEYSLAT 597
L+R +S + Y +V G K IY +GF EP+ + S+ +LV +Y SL
Sbjct: 305 LIRESSQRGC-YACSVVVDGDTKHCVIYRTATGFGFAEPYNLYGSLKELVLHYQHASLVQ 363
Query: 598 CNSSLDIKL 624
N +L + L
Sbjct: 364 HNDALTVTL 372
Score = 32.3 bits (70), Expect = 2.4
Identities = 14/35 (40%), Positives = 22/35 (62%)
Frame = +2
Query: 758 KYTRLXEEVTLKRQALXAFREAVKMCEDPLNYXEK 862
+YTR +E+ +KR A+ AF E +K+ E+ EK
Sbjct: 126 EYTRTSQELQMKRTAIEAFNETIKIFEEQGQTQEK 160
>BC014170-1|AAH14170.2| 324|Homo sapiens PIK3R2 protein protein.
Length = 324
Score = 64.9 bits (151), Expect = 4e-10
Identities = 40/129 (31%), Positives = 62/129 (48%), Gaps = 1/129 (0%)
Frame = +1
Query: 241 KQRKLDNYTAPSSPDDEIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKLRDTRDGTF 420
+Q+K++ + + ++ + P H E WY G I R +A E L RDGTF
Sbjct: 183 RQKKINEWLGIKNETEDQYALMEDEDDLPHH--EERTWYVGKINRTQAEEMLSGKRDGTF 240
Query: 421 LVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFE-FKSVVDLVCYYSEYSLAT 597
L+R +S + Y +V G K IY +GF EP+ + S+ +LV +Y SL
Sbjct: 241 LIRESSQRGC-YACSVVVDGDTKHCVIYRTATGFGFAEPYNLYGSLKELVLHYQHASLVQ 299
Query: 598 CNSSLDIKL 624
N +L + L
Sbjct: 300 HNDALTVTL 308
Score = 32.3 bits (70), Expect = 2.4
Identities = 14/35 (40%), Positives = 22/35 (62%)
Frame = +2
Query: 758 KYTRLXEEVTLKRQALXAFREAVKMCEDPLNYXEK 862
+YTR +E+ +KR A+ AF E +K+ E+ EK
Sbjct: 62 EYTRTSQELQMKRTAIEAFNETIKIFEEQGQTQEK 96
>X83931-1|CAA58783.1| 539|Homo sapiens VAV protein.
Length = 539
Score = 58.8 bits (136), Expect = 2e-08
Identities = 34/100 (34%), Positives = 47/100 (47%)
Frame = +1
Query: 325 PEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIY 504
P L WY G + R A L + DGTFLVR + + ++++ K IKI
Sbjct: 364 PPQDLSVHLWYAGPMERAGAESILANRSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKIM 423
Query: 505 HHEGRYGFREPFEFKSVVDLVCYYSEYSLATCNSSLDIKL 624
EG Y E F+ + +LV +Y + SL C SLD L
Sbjct: 424 TAEGLYRITEKKAFRGLTELVEFYQQNSLKDCFKSLDTTL 463
>BC013361-1|AAH13361.2| 790|Homo sapiens VAV1 protein protein.
Length = 790
Score = 58.8 bits (136), Expect = 2e-08
Identities = 34/100 (34%), Positives = 47/100 (47%)
Frame = +1
Query: 325 PEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIY 504
P L WY G + R A L + DGTFLVR + + ++++ K IKI
Sbjct: 607 PPQDLSVHLWYAGPMERAGAESILANRSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKIM 666
Query: 505 HHEGRYGFREPFEFKSVVDLVCYYSEYSLATCNSSLDIKL 624
EG Y E F+ + +LV +Y + SL C SLD L
Sbjct: 667 TAEGLYRITEKKAFRGLTELVEFYQQNSLKDCFKSLDTTL 706
>AF030227-1|AAC25011.1| 845|Homo sapiens vav protein protein.
Length = 845
Score = 58.8 bits (136), Expect = 2e-08
Identities = 34/100 (34%), Positives = 47/100 (47%)
Frame = +1
Query: 325 PEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIY 504
P L WY G + R A L + DGTFLVR + + ++++ K IKI
Sbjct: 662 PPQDLSVHLWYAGPMERAGAESILANRSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKIM 721
Query: 505 HHEGRYGFREPFEFKSVVDLVCYYSEYSLATCNSSLDIKL 624
EG Y E F+ + +LV +Y + SL C SLD L
Sbjct: 722 TAEGLYRITEKKAFRGLTELVEFYQQNSLKDCFKSLDTTL 761
>BC010399-1|AAH10399.1| 198|Homo sapiens suppressor of cytokine
signaling 2 protein.
Length = 198
Score = 58.4 bits (135), Expect = 3e-08
Identities = 28/82 (34%), Positives = 48/82 (58%), Gaps = 7/82 (8%)
Frame = +1
Query: 352 WYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFR 531
WYWG +T +EA EKL++ +GTFL+R++S+ D T++V+ ++I + +G++
Sbjct: 48 WYWGSMTVNEAKEKLKEAPEGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGKFRLD 107
Query: 532 EPF-------EFKSVVDLVCYY 576
+F SVV L+ YY
Sbjct: 108 SIICVKSKLKQFDSVVHLIDYY 129
>AF037989-1|AAC34745.1| 198|Homo sapiens STAT-induced STAT
inhibitor-2 protein.
Length = 198
Score = 58.4 bits (135), Expect = 3e-08
Identities = 28/82 (34%), Positives = 48/82 (58%), Gaps = 7/82 (8%)
Frame = +1
Query: 352 WYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFR 531
WYWG +T +EA EKL++ +GTFL+R++S+ D T++V+ ++I + +G++
Sbjct: 48 WYWGSMTVNEAKEKLKEAPEGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGKFRLD 107
Query: 532 EPF-------EFKSVVDLVCYY 576
+F SVV L+ YY
Sbjct: 108 SIICVKSKLKQFDSVVHLIDYY 129
>AF020590-1|AAC98896.1| 197|Homo sapiens suppressor of cytokine
signalling-2 protein.
Length = 197
Score = 58.4 bits (135), Expect = 3e-08
Identities = 28/82 (34%), Positives = 48/82 (58%), Gaps = 7/82 (8%)
Frame = +1
Query: 352 WYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFR 531
WYWG +T +EA EKL++ +GTFL+R++S+ D T++V+ ++I + +G++
Sbjct: 47 WYWGSMTVNEAKEKLKEAPEGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGKFRLD 106
Query: 532 EPF-------EFKSVVDLVCYY 576
+F SVV L+ YY
Sbjct: 107 SIICVKSKLKQFDSVVHLIDYY 128
>AB006966-1|BAA22536.1| 198|Homo sapiens CIS2 protein.
Length = 198
Score = 58.4 bits (135), Expect = 3e-08
Identities = 28/82 (34%), Positives = 48/82 (58%), Gaps = 7/82 (8%)
Frame = +1
Query: 352 WYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFR 531
WYWG +T +EA EKL++ +GTFL+R++S+ D T++V+ ++I + +G++
Sbjct: 48 WYWGSMTVNEAKEKLKEAPEGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGKFRLD 107
Query: 532 EPF-------EFKSVVDLVCYY 576
+F SVV L+ YY
Sbjct: 108 SIICVKSKLKQFDSVVHLIDYY 129
>AB004903-1|BAA22429.1| 198|Homo sapiens STAT induced STAT
inhibitor-2 protein.
Length = 198
Score = 58.4 bits (135), Expect = 3e-08
Identities = 28/82 (34%), Positives = 48/82 (58%), Gaps = 7/82 (8%)
Frame = +1
Query: 352 WYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFR 531
WYWG +T +EA EKL++ +GTFL+R++S+ D T++V+ ++I + +G++
Sbjct: 48 WYWGSMTVNEAKEKLKEAPEGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGKFRLD 107
Query: 532 EPF-------EFKSVVDLVCYY 576
+F SVV L+ YY
Sbjct: 108 SIICVKSKLKQFDSVVHLIDYY 129
>BC020082-1|AAH20082.1| 535|Homo sapiens suppressor of cytokine
signaling 6 protein.
Length = 535
Score = 58.0 bits (134), Expect = 4e-08
Identities = 31/75 (41%), Positives = 44/75 (58%), Gaps = 3/75 (4%)
Frame = +1
Query: 352 WYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFR 531
WYWG ITR EA KL + DG+FLVR++S+ +L+ R G +I H GR+ F
Sbjct: 384 WYWGPITRWEAEGKLANVPDGSFLVRDSSDDRYLLSLSFRSHGKTLHTRIEHSNGRFSFY 443
Query: 532 EPFEFK---SVVDLV 567
E + + S+VDL+
Sbjct: 444 EQPDVEGHTSIVDLI 458
>AB006968-1|BAA22538.1| 535|Homo sapiens CIS4 protein.
Length = 535
Score = 58.0 bits (134), Expect = 4e-08
Identities = 31/75 (41%), Positives = 44/75 (58%), Gaps = 3/75 (4%)
Frame = +1
Query: 352 WYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFR 531
WYWG ITR EA KL + DG+FLVR++S+ +L+ R G +I H GR+ F
Sbjct: 384 WYWGPITRWEAEGKLANVPDGSFLVRDSSDDRYLLSLSFRSHGKTLHTRIEHSNGRFSFY 443
Query: 532 EPFEFK---SVVDLV 567
E + + S+VDL+
Sbjct: 444 EQPDVEGHTSIVDLI 458
>X14034-1|CAA32194.1| 1252|Homo sapiens protein ( Human mRNA for
phospholipase C. ).
Length = 1252
Score = 56.8 bits (131), Expect = 1e-07
Identities = 36/114 (31%), Positives = 55/114 (48%), Gaps = 1/114 (0%)
Frame = +1
Query: 253 LDNYTAPSSPDDEIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKL-RDTRDGTFLVR 429
+ +Y P E + + P +P E+ WY+ ++R EA + L R RDG FL+R
Sbjct: 614 IQHYRETHLPCAEFELRLTDPVPNPNPH-ESKPWYYDSLSRGEAEDMLMRIPRDGAFLIR 672
Query: 430 NASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSL 591
DS Y +T R G K +I + F+S+V+LV YY ++SL
Sbjct: 673 KREGSDS-YAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYEKHSL 725
Score = 37.1 bits (82), Expect = 0.085
Identities = 34/117 (29%), Positives = 52/117 (44%), Gaps = 12/117 (10%)
Frame = +1
Query: 277 SPDDEIMVEIGVPQQSPEHSLEAAE-WYWGDITRDEANEKLRDT-------RDGTFLVRN 432
S D E +E VPQ P L E W+ + + + EKL +DGTFLVR
Sbjct: 506 SDDIEQTMEEEVPQDIPPTELHFGEKWFHKKVEKRTSAEKLLQEYCMETGGKDGTFLVRE 565
Query: 433 ASNKDSGYTLTVRKGGANKLIKIYH-HEG---RYGFREPFEFKSVVDLVCYYSEYSL 591
+ + YTL+ + G + +I EG +Y + F+ + L+ +Y E L
Sbjct: 566 SETFPNDYTLSFWRSGRVQHCRIRSTMEGGTLKYYLTDNLRFRRMYALIQHYRETHL 622
>M37238-1|AAA60112.1| 1252|Homo sapiens PLC1 protein.
Length = 1252
Score = 56.8 bits (131), Expect = 1e-07
Identities = 36/114 (31%), Positives = 55/114 (48%), Gaps = 1/114 (0%)
Frame = +1
Query: 253 LDNYTAPSSPDDEIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKL-RDTRDGTFLVR 429
+ +Y P E + + P +P E+ WY+ ++R EA + L R RDG FL+R
Sbjct: 614 IQHYRETHLPCAEFELRLTDPVPNPNPH-ESKPWYYDSLSRGEAEDMLMRIPRDGAFLIR 672
Query: 430 NASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSL 591
DS Y +T R G K +I + F+S+V+LV YY ++SL
Sbjct: 673 KREGSDS-YAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYEKHSL 725
Score = 37.1 bits (82), Expect = 0.085
Identities = 34/117 (29%), Positives = 52/117 (44%), Gaps = 12/117 (10%)
Frame = +1
Query: 277 SPDDEIMVEIGVPQQSPEHSLEAAE-WYWGDITRDEANEKLRDT-------RDGTFLVRN 432
S D E +E VPQ P L E W+ + + + EKL +DGTFLVR
Sbjct: 506 SDDIEQTMEEEVPQDIPPTELHFGEKWFHKKVEKRTSAEKLLQEYCMETGGKDGTFLVRE 565
Query: 433 ASNKDSGYTLTVRKGGANKLIKIYH-HEG---RYGFREPFEFKSVVDLVCYYSEYSL 591
+ + YTL+ + G + +I EG +Y + F+ + L+ +Y E L
Sbjct: 566 SETFPNDYTLSFWRSGRVQHCRIRSTMEGGTLKYYLTDNLRFRRMYALIQHYRETHL 622
>AY364256-1|AAQ76815.1| 1252|Homo sapiens phospholipase C gamma 2
protein.
Length = 1252
Score = 56.8 bits (131), Expect = 1e-07
Identities = 36/114 (31%), Positives = 55/114 (48%), Gaps = 1/114 (0%)
Frame = +1
Query: 253 LDNYTAPSSPDDEIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKL-RDTRDGTFLVR 429
+ +Y P E + + P +P E+ WY+ ++R EA + L R RDG FL+R
Sbjct: 614 IQHYRETHLPCAEFELRLTDPVPNPNPH-ESKPWYYDSLSRGEAEDMLMRIPRDGAFLIR 672
Query: 430 NASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSL 591
DS Y +T R G K +I + F+S+V+LV YY ++SL
Sbjct: 673 KREGSDS-YAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYEKHSL 725
Score = 37.1 bits (82), Expect = 0.085
Identities = 34/117 (29%), Positives = 52/117 (44%), Gaps = 12/117 (10%)
Frame = +1
Query: 277 SPDDEIMVEIGVPQQSPEHSLEAAE-WYWGDITRDEANEKLRDT-------RDGTFLVRN 432
S D E +E VPQ P L E W+ + + + EKL +DGTFLVR
Sbjct: 506 SDDIEQTMEEEVPQDIPPTELHFGEKWFHKKVEKRTSAEKLLQEYCMETGGKDGTFLVRE 565
Query: 433 ASNKDSGYTLTVRKGGANKLIKIYH-HEG---RYGFREPFEFKSVVDLVCYYSEYSL 591
+ + YTL+ + G + +I EG +Y + F+ + L+ +Y E L
Sbjct: 566 SETFPNDYTLSFWRSGRVQHCRIRSTMEGGTLKYYLTDNLRFRRMYALIQHYRETHL 622
>BC018646-1|AAH18646.1| 1265|Homo sapiens PLCG2 protein protein.
Length = 1265
Score = 56.4 bits (130), Expect = 1e-07
Identities = 35/102 (34%), Positives = 52/102 (50%), Gaps = 1/102 (0%)
Frame = +1
Query: 289 EIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKL-RDTRDGTFLVRNASNKDSGYTLT 465
E+ + VP +P E+ WY+ ++R EA + L R RDG FL+R DS Y +T
Sbjct: 628 ELRLTDPVPNPNPH---ESKPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREGSDS-YAIT 683
Query: 466 VRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSL 591
R G K +I + F+S+V+LV YY ++SL
Sbjct: 684 FRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYEKHSL 725
Score = 38.7 bits (86), Expect = 0.028
Identities = 35/117 (29%), Positives = 52/117 (44%), Gaps = 12/117 (10%)
Frame = +1
Query: 277 SPDDEIMVEIGVPQQSPEHSLEAAE-WYWGDITRDEANEKLRDT-------RDGTFLVRN 432
S D E +E VPQ P L E W+ + + + EKL +DGTFLVR
Sbjct: 506 SDDIEQTMEEEVPQDIPPTELHFGEKWFHKKVEKRTSAEKLLQEYCMETGGKDGTFLVRE 565
Query: 433 ASNKDSGYTLTVRKGGANKLIKIYH-HEG---RYGFREPFEFKSVVDLVCYYSEYSL 591
+ + YTL+ + G + +I EG +Y + F S+ L+ +Y E L
Sbjct: 566 SETFPNDYTLSFWRSGRVQHCRIRSTMEGGTLKYYLTDNLTFSSIYALIQHYRETHL 622
>BC014561-1|AAH14561.1| 1265|Homo sapiens PLCG2 protein protein.
Length = 1265
Score = 56.4 bits (130), Expect = 1e-07
Identities = 35/102 (34%), Positives = 52/102 (50%), Gaps = 1/102 (0%)
Frame = +1
Query: 289 EIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKL-RDTRDGTFLVRNASNKDSGYTLT 465
E+ + VP +P E+ WY+ ++R EA + L R RDG FL+R DS Y +T
Sbjct: 628 ELRLTDPVPNPNPH---ESKPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREGSDS-YAIT 683
Query: 466 VRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSL 591
R G K +I + F+S+V+LV YY ++SL
Sbjct: 684 FRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYEKHSL 725
Score = 38.7 bits (86), Expect = 0.028
Identities = 35/117 (29%), Positives = 52/117 (44%), Gaps = 12/117 (10%)
Frame = +1
Query: 277 SPDDEIMVEIGVPQQSPEHSLEAAE-WYWGDITRDEANEKLRDT-------RDGTFLVRN 432
S D E +E VPQ P L E W+ + + + EKL +DGTFLVR
Sbjct: 506 SDDIEQTMEEEVPQDIPPTELHFGEKWFHKKVEKRTSAEKLLQEYCMETGGKDGTFLVRE 565
Query: 433 ASNKDSGYTLTVRKGGANKLIKIYH-HEG---RYGFREPFEFKSVVDLVCYYSEYSL 591
+ + YTL+ + G + +I EG +Y + F S+ L+ +Y E L
Sbjct: 566 SETFPNDYTLSFWRSGRVQHCRIRSTMEGGTLKYYLTDNLTFSSIYALIQHYRETHL 622
>BC011772-1|AAH11772.1| 1265|Homo sapiens PLCG2 protein protein.
Length = 1265
Score = 56.4 bits (130), Expect = 1e-07
Identities = 35/102 (34%), Positives = 52/102 (50%), Gaps = 1/102 (0%)
Frame = +1
Query: 289 EIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKL-RDTRDGTFLVRNASNKDSGYTLT 465
E+ + VP +P E+ WY+ ++R EA + L R RDG FL+R DS Y +T
Sbjct: 628 ELRLTDPVPNPNPH---ESKPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREGSDS-YAIT 683
Query: 466 VRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSL 591
R G K +I + F+S+V+LV YY ++SL
Sbjct: 684 FRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYEKHSL 725
Score = 38.7 bits (86), Expect = 0.028
Identities = 35/117 (29%), Positives = 52/117 (44%), Gaps = 12/117 (10%)
Frame = +1
Query: 277 SPDDEIMVEIGVPQQSPEHSLEAAE-WYWGDITRDEANEKLRDT-------RDGTFLVRN 432
S D E +E VPQ P L E W+ + + + EKL +DGTFLVR
Sbjct: 506 SDDIEQTMEEEVPQDIPPTELHFGEKWFHKKVEKRTSAEKLLQEYCMETGGKDGTFLVRE 565
Query: 433 ASNKDSGYTLTVRKGGANKLIKIYH-HEG---RYGFREPFEFKSVVDLVCYYSEYSL 591
+ + YTL+ + G + +I EG +Y + F S+ L+ +Y E L
Sbjct: 566 SETFPNDYTLSFWRSGRVQHCRIRSTMEGGTLKYYLTDNLTFSSIYALIQHYRETHL 622
>BC007565-1|AAH07565.1| 1265|Homo sapiens PLCG2 protein protein.
Length = 1265
Score = 56.4 bits (130), Expect = 1e-07
Identities = 35/102 (34%), Positives = 52/102 (50%), Gaps = 1/102 (0%)
Frame = +1
Query: 289 EIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKL-RDTRDGTFLVRNASNKDSGYTLT 465
E+ + VP +P E+ WY+ ++R EA + L R RDG FL+R DS Y +T
Sbjct: 628 ELRLTDPVPNPNPH---ESKPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREGSDS-YAIT 683
Query: 466 VRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSL 591
R G K +I + F+S+V+LV YY ++SL
Sbjct: 684 FRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYEKHSL 725
Score = 38.7 bits (86), Expect = 0.028
Identities = 35/117 (29%), Positives = 52/117 (44%), Gaps = 12/117 (10%)
Frame = +1
Query: 277 SPDDEIMVEIGVPQQSPEHSLEAAE-WYWGDITRDEANEKLRDT-------RDGTFLVRN 432
S D E +E VPQ P L E W+ + + + EKL +DGTFLVR
Sbjct: 506 SDDIEQTMEEEVPQDIPPTELHFGEKWFHKKVEKRTSAEKLLQEYCMETGGKDGTFLVRE 565
Query: 433 ASNKDSGYTLTVRKGGANKLIKIYH-HEG---RYGFREPFEFKSVVDLVCYYSEYSL 591
+ + YTL+ + G + +I EG +Y + F S+ L+ +Y E L
Sbjct: 566 SETFPNDYTLSFWRSGRVQHCRIRSTMEGGTLKYYLTDNLTFSSIYALIQHYRETHL 622
>AB208914-1|BAD92151.1| 1278|Homo sapiens
1-phosphatidylinositol-4,5-bisphosphate
phosphodiesterase gamma 2 variant protein.
Length = 1278
Score = 56.4 bits (130), Expect = 1e-07
Identities = 35/102 (34%), Positives = 52/102 (50%), Gaps = 1/102 (0%)
Frame = +1
Query: 289 EIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKL-RDTRDGTFLVRNASNKDSGYTLT 465
E+ + VP +P E+ WY+ ++R EA + L R RDG FL+R DS Y +T
Sbjct: 641 ELRLTDPVPNPNPH---ESKPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREGSDS-YAIT 696
Query: 466 VRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSL 591
R G K +I + F+S+V+LV YY ++SL
Sbjct: 697 FRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYEKHSL 738
Score = 38.7 bits (86), Expect = 0.028
Identities = 35/117 (29%), Positives = 52/117 (44%), Gaps = 12/117 (10%)
Frame = +1
Query: 277 SPDDEIMVEIGVPQQSPEHSLEAAE-WYWGDITRDEANEKLRDT-------RDGTFLVRN 432
S D E +E VPQ P L E W+ + + + EKL +DGTFLVR
Sbjct: 519 SDDIEQTMEEEVPQDIPPTELHFGEKWFHKKVEKRTSAEKLLQEYCMETGGKDGTFLVRE 578
Query: 433 ASNKDSGYTLTVRKGGANKLIKIYH-HEG---RYGFREPFEFKSVVDLVCYYSEYSL 591
+ + YTL+ + G + +I EG +Y + F S+ L+ +Y E L
Sbjct: 579 SETFPNDYTLSFWRSGRVQHCRIRSTMEGGTLKYYLTDNLTFSSIYALIQHYRETHL 635
>K03218-1|AAA60584.1| 536|Homo sapiens SRC protein.
Length = 536
Score = 55.2 bits (127), Expect = 3e-07
Identities = 32/102 (31%), Positives = 52/102 (50%), Gaps = 8/102 (7%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRD--GTFLVRNASNKDSGYTLTVRKGGANKLI 495
+P S++A EWY+G ITR E+ L + + GTFLVR + Y L+V K +
Sbjct: 141 APSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGL 200
Query: 496 KIYHHE------GRYGFREPFEFKSVVDLVCYYSEYSLATCN 603
+ H++ G + +F S+ LV YYS+++ C+
Sbjct: 201 NVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCH 242
>BC051270-1|AAH51270.2| 536|Homo sapiens v-src sarcoma
(Schmidt-Ruppin A-2) viral oncogene homolog (avian)
protein.
Length = 536
Score = 55.2 bits (127), Expect = 3e-07
Identities = 32/102 (31%), Positives = 52/102 (50%), Gaps = 8/102 (7%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRD--GTFLVRNASNKDSGYTLTVRKGGANKLI 495
+P S++A EWY+G ITR E+ L + + GTFLVR + Y L+V K +
Sbjct: 141 APSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGL 200
Query: 496 KIYHHE------GRYGFREPFEFKSVVDLVCYYSEYSLATCN 603
+ H++ G + +F S+ LV YYS+++ C+
Sbjct: 201 NVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCH 242
>BC011566-1|AAH11566.1| 536|Homo sapiens SRC protein protein.
Length = 536
Score = 55.2 bits (127), Expect = 3e-07
Identities = 32/102 (31%), Positives = 52/102 (50%), Gaps = 8/102 (7%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRD--GTFLVRNASNKDSGYTLTVRKGGANKLI 495
+P S++A EWY+G ITR E+ L + + GTFLVR + Y L+V K +
Sbjct: 141 APSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGL 200
Query: 496 KIYHHE------GRYGFREPFEFKSVVDLVCYYSEYSLATCN 603
+ H++ G + +F S+ LV YYS+++ C+
Sbjct: 201 NVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCH 242
>AL133293-2|CAC34523.1| 536|Homo sapiens v-src sarcoma
(Schmidt-Ruppin A-2) viral oncogenem exchanger), member
2 protein.
Length = 536
Score = 55.2 bits (127), Expect = 3e-07
Identities = 32/102 (31%), Positives = 52/102 (50%), Gaps = 8/102 (7%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRD--GTFLVRNASNKDSGYTLTVRKGGANKLI 495
+P S++A EWY+G ITR E+ L + + GTFLVR + Y L+V K +
Sbjct: 141 APSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGL 200
Query: 496 KIYHHE------GRYGFREPFEFKSVVDLVCYYSEYSLATCN 603
+ H++ G + +F S+ LV YYS+++ C+
Sbjct: 201 NVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCH 242
>AL133293-1|CAC10573.1| 542|Homo sapiens v-src sarcoma
(Schmidt-Ruppin A-2) viral oncogenem exchanger), member
2 protein.
Length = 542
Score = 55.2 bits (127), Expect = 3e-07
Identities = 32/102 (31%), Positives = 52/102 (50%), Gaps = 8/102 (7%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRD--GTFLVRNASNKDSGYTLTVRKGGANKLI 495
+P S++A EWY+G ITR E+ L + + GTFLVR + Y L+V K +
Sbjct: 147 APSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGL 206
Query: 496 KIYHHE------GRYGFREPFEFKSVVDLVCYYSEYSLATCN 603
+ H++ G + +F S+ LV YYS+++ C+
Sbjct: 207 NVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCH 248
>X16316-1|CAA34383.1| 797|Homo sapiens VAV protein.
Length = 797
Score = 54.8 bits (126), Expect = 4e-07
Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 1/101 (0%)
Frame = +1
Query: 325 PEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANK-LIKI 501
P L WY G + R A L + DGTFLVR + + ++++ K +KI
Sbjct: 613 PPQDLSVHLWYAGPMERAGAESILANRSDGTFLVRQRVKDAAEFAISIKYNVEVKHTVKI 672
Query: 502 YHHEGRYGFREPFEFKSVVDLVCYYSEYSLATCNSSLDIKL 624
EG Y E F+ + +LV +Y + SL C SLD L
Sbjct: 673 MTAEGLYRITEKKAFRGLTELVEFYQQNSLKDCFKSLDTTL 713
>M34667-1|AAA36452.1| 1290|Homo sapiens protein ( Human
phospholipase C-gamma mRNA, complete cds. ).
Length = 1290
Score = 54.4 bits (125), Expect = 5e-07
Identities = 36/102 (35%), Positives = 53/102 (51%), Gaps = 1/102 (0%)
Frame = +1
Query: 289 EIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKL-RDTRDGTFLVRNASNKDSGYTLT 465
E+ + VPQ + E+ EWY +TR +A L R RDG FLVR N+ + Y ++
Sbjct: 650 EMRLSEPVPQTNAH---ESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKR-NEPNSYAIS 705
Query: 466 VRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSL 591
R G K ++ EG+ EF S+VDL+ YY ++ L
Sbjct: 706 FRAEGKIKHCRV-QQEGQTVMLGNSEFDSLVDLISYYEKHPL 746
Score = 31.1 bits (67), Expect = 5.6
Identities = 19/69 (27%), Positives = 34/69 (49%), Gaps = 4/69 (5%)
Frame = +1
Query: 409 DGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEG----RYGFREPFEFKSVVDLVCYY 576
DG+FLVR + YTL+ + G + +I+ + ++ + F S+ DL+ +Y
Sbjct: 580 DGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHY 639
Query: 577 SEYSLATCN 603
+ L CN
Sbjct: 640 QQVPL-RCN 647
>DQ297143-1|ABB84466.1| 1291|Homo sapiens phospholipase C, gamma 1
protein.
Length = 1291
Score = 54.4 bits (125), Expect = 5e-07
Identities = 36/102 (35%), Positives = 53/102 (51%), Gaps = 1/102 (0%)
Frame = +1
Query: 289 EIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKL-RDTRDGTFLVRNASNKDSGYTLT 465
E+ + VPQ + E+ EWY +TR +A L R RDG FLVR N+ + Y ++
Sbjct: 650 EMRLSEPVPQTNAH---ESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKR-NEPNSYAIS 705
Query: 466 VRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSL 591
R G K ++ EG+ EF S+VDL+ YY ++ L
Sbjct: 706 FRAEGKIKHCRV-QQEGQTVMLGNSEFDSLVDLISYYEKHPL 746
Score = 31.1 bits (67), Expect = 5.6
Identities = 19/69 (27%), Positives = 34/69 (49%), Gaps = 4/69 (5%)
Frame = +1
Query: 409 DGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEG----RYGFREPFEFKSVVDLVCYY 576
DG+FLVR + YTL+ + G + +I+ + ++ + F S+ DL+ +Y
Sbjct: 580 DGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHY 639
Query: 577 SEYSLATCN 603
+ L CN
Sbjct: 640 QQVPL-RCN 647
>AL591042-2|CAI14458.1| 753|Homo sapiens vav 3 oncogene protein.
Length = 753
Score = 54.4 bits (125), Expect = 5e-07
Identities = 29/91 (31%), Positives = 50/91 (54%)
Frame = +1
Query: 352 WYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFR 531
WY G + R +A +L + + T+LVR+ + + Y ++++ K IKI +G +
Sbjct: 578 WYAGAMERLQAETELINRVNSTYLVRHRTKESGEYAISIKYNNEAKHIKILTRDGFFHIA 637
Query: 532 EPFEFKSVVDLVCYYSEYSLATCNSSLDIKL 624
E +FKS+++LV YY +SL +LD L
Sbjct: 638 ENRKFKSLMELVEYYKHHSLKEGFRTLDTTL 668
>AL591042-1|CAI14457.1| 847|Homo sapiens vav 3 oncogene protein.
Length = 847
Score = 54.4 bits (125), Expect = 5e-07
Identities = 29/91 (31%), Positives = 50/91 (54%)
Frame = +1
Query: 352 WYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFR 531
WY G + R +A +L + + T+LVR+ + + Y ++++ K IKI +G +
Sbjct: 672 WYAGAMERLQAETELINRVNSTYLVRHRTKESGEYAISIKYNNEAKHIKILTRDGFFHIA 731
Query: 532 EPFEFKSVVDLVCYYSEYSLATCNSSLDIKL 624
E +FKS+++LV YY +SL +LD L
Sbjct: 732 ENRKFKSLMELVEYYKHHSLKEGFRTLDTTL 762
>AL513206-2|CAH73196.1| 753|Homo sapiens vav 3 oncogene protein.
Length = 753
Score = 54.4 bits (125), Expect = 5e-07
Identities = 29/91 (31%), Positives = 50/91 (54%)
Frame = +1
Query: 352 WYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFR 531
WY G + R +A +L + + T+LVR+ + + Y ++++ K IKI +G +
Sbjct: 578 WYAGAMERLQAETELINRVNSTYLVRHRTKESGEYAISIKYNNEAKHIKILTRDGFFHIA 637
Query: 532 EPFEFKSVVDLVCYYSEYSLATCNSSLDIKL 624
E +FKS+++LV YY +SL +LD L
Sbjct: 638 ENRKFKSLMELVEYYKHHSLKEGFRTLDTTL 668
>AL513206-1|CAH73195.1| 847|Homo sapiens vav 3 oncogene protein.
Length = 847
Score = 54.4 bits (125), Expect = 5e-07
Identities = 29/91 (31%), Positives = 50/91 (54%)
Frame = +1
Query: 352 WYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFR 531
WY G + R +A +L + + T+LVR+ + + Y ++++ K IKI +G +
Sbjct: 672 WYAGAMERLQAETELINRVNSTYLVRHRTKESGEYAISIKYNNEAKHIKILTRDGFFHIA 731
Query: 532 EPFEFKSVVDLVCYYSEYSLATCNSSLDIKL 624
E +FKS+++LV YY +SL +LD L
Sbjct: 732 ENRKFKSLMELVEYYKHHSLKEGFRTLDTTL 762
>AL391235-1|CAH72458.1| 847|Homo sapiens vav 3 oncogene protein.
Length = 847
Score = 54.4 bits (125), Expect = 5e-07
Identities = 29/91 (31%), Positives = 50/91 (54%)
Frame = +1
Query: 352 WYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFR 531
WY G + R +A +L + + T+LVR+ + + Y ++++ K IKI +G +
Sbjct: 672 WYAGAMERLQAETELINRVNSTYLVRHRTKESGEYAISIKYNNEAKHIKILTRDGFFHIA 731
Query: 532 EPFEFKSVVDLVCYYSEYSLATCNSSLDIKL 624
E +FKS+++LV YY +SL +LD L
Sbjct: 732 ENRKFKSLMELVEYYKHHSLKEGFRTLDTTL 762
>AL353892-1|CAI21786.1| 847|Homo sapiens vav 3 oncogene protein.
Length = 847
Score = 54.4 bits (125), Expect = 5e-07
Identities = 29/91 (31%), Positives = 50/91 (54%)
Frame = +1
Query: 352 WYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFR 531
WY G + R +A +L + + T+LVR+ + + Y ++++ K IKI +G +
Sbjct: 672 WYAGAMERLQAETELINRVNSTYLVRHRTKESGEYAISIKYNNEAKHIKILTRDGFFHIA 731
Query: 532 EPFEFKSVVDLVCYYSEYSLATCNSSLDIKL 624
E +FKS+++LV YY +SL +LD L
Sbjct: 732 ENRKFKSLMELVEYYKHHSLKEGFRTLDTTL 762
>AL022394-3|CAA18537.1| 1290|Homo sapiens phospholipase C, gamma 1
protein.
Length = 1290
Score = 54.4 bits (125), Expect = 5e-07
Identities = 36/102 (35%), Positives = 53/102 (51%), Gaps = 1/102 (0%)
Frame = +1
Query: 289 EIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKL-RDTRDGTFLVRNASNKDSGYTLT 465
E+ + VPQ + E+ EWY +TR +A L R RDG FLVR N+ + Y ++
Sbjct: 650 EMRLSEPVPQTNAH---ESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKR-NEPNSYAIS 705
Query: 466 VRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSL 591
R G K ++ EG+ EF S+VDL+ YY ++ L
Sbjct: 706 FRAEGKIKHCRV-QQEGQTVMLGNSEFDSLVDLISYYEKHPL 746
Score = 31.1 bits (67), Expect = 5.6
Identities = 19/69 (27%), Positives = 34/69 (49%), Gaps = 4/69 (5%)
Frame = +1
Query: 409 DGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEG----RYGFREPFEFKSVVDLVCYY 576
DG+FLVR + YTL+ + G + +I+ + ++ + F S+ DL+ +Y
Sbjct: 580 DGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHY 639
Query: 577 SEYSLATCN 603
+ L CN
Sbjct: 640 QQVPL-RCN 647
>AL022394-2|CAM28260.1| 1291|Homo sapiens phospholipase C, gamma 1
protein.
Length = 1291
Score = 54.4 bits (125), Expect = 5e-07
Identities = 36/102 (35%), Positives = 53/102 (51%), Gaps = 1/102 (0%)
Frame = +1
Query: 289 EIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKL-RDTRDGTFLVRNASNKDSGYTLT 465
E+ + VPQ + E+ EWY +TR +A L R RDG FLVR N+ + Y ++
Sbjct: 650 EMRLSEPVPQTNAH---ESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKR-NEPNSYAIS 705
Query: 466 VRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSL 591
R G K ++ EG+ EF S+VDL+ YY ++ L
Sbjct: 706 FRAEGKIKHCRV-QQEGQTVMLGNSEFDSLVDLISYYEKHPL 746
Score = 31.1 bits (67), Expect = 5.6
Identities = 19/69 (27%), Positives = 34/69 (49%), Gaps = 4/69 (5%)
Frame = +1
Query: 409 DGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEG----RYGFREPFEFKSVVDLVCYY 576
DG+FLVR + YTL+ + G + +I+ + ++ + F S+ DL+ +Y
Sbjct: 580 DGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHY 639
Query: 577 SEYSLATCN 603
+ L CN
Sbjct: 640 QQVPL-RCN 647
>AF118887-1|AAD20349.1| 847|Homo sapiens VAV-3 protein protein.
Length = 847
Score = 54.4 bits (125), Expect = 5e-07
Identities = 29/91 (31%), Positives = 50/91 (54%)
Frame = +1
Query: 352 WYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFR 531
WY G + R +A +L + + T+LVR+ + + Y ++++ K IKI +G +
Sbjct: 672 WYAGAMERLQAETELINRVNSTYLVRHRTKESGEYAISIKYNNEAKHIKILTRDGFFHIA 731
Query: 532 EPFEFKSVVDLVCYYSEYSLATCNSSLDIKL 624
E +FKS+++LV YY +SL +LD L
Sbjct: 732 ENRKFKSLMELVEYYKHHSLKEGFRTLDTTL 762
>AF118886-1|AAD20348.1| 753|Homo sapiens VAV-3 protein beta isoform
protein.
Length = 753
Score = 54.4 bits (125), Expect = 5e-07
Identities = 29/91 (31%), Positives = 50/91 (54%)
Frame = +1
Query: 352 WYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFR 531
WY G + R +A +L + + T+LVR+ + + Y ++++ K IKI +G +
Sbjct: 578 WYAGAMERLQAETELINRVNSTYLVRHRTKESGEYAISIKYNNEAKHIKILTRDGFFHIA 637
Query: 532 EPFEFKSVVDLVCYYSEYSLATCNSSLDIKL 624
E +FKS+++LV YY +SL +LD L
Sbjct: 638 ENRKFKSLMELVEYYKHHSLKEGFRTLDTTL 668
>AF067817-1|AAC79695.1| 847|Homo sapiens VAV-3 protein protein.
Length = 847
Score = 54.4 bits (125), Expect = 5e-07
Identities = 29/91 (31%), Positives = 50/91 (54%)
Frame = +1
Query: 352 WYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFR 531
WY G + R +A +L + + T+LVR+ + + Y ++++ K IKI +G +
Sbjct: 672 WYAGAMERLQAETELINRVNSTYLVRHRTKESGEYAISIKYNNEAKHIKILTRDGFFHIA 731
Query: 532 EPFEFKSVVDLVCYYSEYSLATCNSSLDIKL 624
E +FKS+++LV YY +SL +LD L
Sbjct: 732 ENRKFKSLMELVEYYKHHSLKEGFRTLDTTL 762
>AB210028-1|BAE06110.1| 1412|Homo sapiens PLCG1 variant protein
protein.
Length = 1412
Score = 54.4 bits (125), Expect = 5e-07
Identities = 36/102 (35%), Positives = 53/102 (51%), Gaps = 1/102 (0%)
Frame = +1
Query: 289 EIMVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKL-RDTRDGTFLVRNASNKDSGYTLT 465
E+ + VPQ + E+ EWY +TR +A L R RDG FLVR N+ + Y ++
Sbjct: 772 EMRLSEPVPQTNAH---ESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKR-NEPNSYAIS 827
Query: 466 VRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSL 591
R G K ++ EG+ EF S+VDL+ YY ++ L
Sbjct: 828 FRAEGKIKHCRV-QQEGQTVMLGNSEFDSLVDLISYYEKHPL 868
Score = 31.1 bits (67), Expect = 5.6
Identities = 19/69 (27%), Positives = 34/69 (49%), Gaps = 4/69 (5%)
Frame = +1
Query: 409 DGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEG----RYGFREPFEFKSVVDLVCYY 576
DG+FLVR + YTL+ + G + +I+ + ++ + F S+ DL+ +Y
Sbjct: 702 DGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHY 761
Query: 577 SEYSLATCN 603
+ L CN
Sbjct: 762 QQVPL-RCN 769
>X74765-1|CAB58562.1| 450|Homo sapiens protein tyrosine kinase
protein.
Length = 450
Score = 53.6 bits (123), Expect = 9e-07
Identities = 29/101 (28%), Positives = 48/101 (47%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEG 516
L W+ G ITR++A L G FLVR ++N YTL V G + +I +H
Sbjct: 77 LSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHAS 136
Query: 517 RYGFREPFEFKSVVDLVCYYSEYSLATCNSSLDIKLLXSIV 639
+ E F++++ LV +Y+ + C + K++ V
Sbjct: 137 KLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVMEGTV 177
>X60114-1|CAA42713.1| 450|Homo sapiens put. cytoplasmic tyrosine
kinase protein.
Length = 450
Score = 53.6 bits (123), Expect = 9e-07
Identities = 29/101 (28%), Positives = 48/101 (47%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEG 516
L W+ G ITR++A L G FLVR ++N YTL V G + +I +H
Sbjct: 77 LSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHAS 136
Query: 517 RYGFREPFEFKSVVDLVCYYSEYSLATCNSSLDIKLLXSIV 639
+ E F++++ LV +Y+ + C + K++ V
Sbjct: 137 KLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVMEGTV 177
>X59932-1|CAA42556.1| 450|Homo sapiens c-src-kinase protein.
Length = 450
Score = 53.6 bits (123), Expect = 9e-07
Identities = 29/101 (28%), Positives = 48/101 (47%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEG 516
L W+ G ITR++A L G FLVR ++N YTL V G + +I +H
Sbjct: 77 LSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHAS 136
Query: 517 RYGFREPFEFKSVVDLVCYYSEYSLATCNSSLDIKLLXSIV 639
+ E F++++ LV +Y+ + C + K++ V
Sbjct: 137 KLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVMEGTV 177
>DQ075211-1|AAY57329.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 53.6 bits (123), Expect = 9e-07
Identities = 29/101 (28%), Positives = 48/101 (47%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEG 516
L W+ G ITR++A L G FLVR ++N YTL V G + +I +H
Sbjct: 77 LSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHAS 136
Query: 517 RYGFREPFEFKSVVDLVCYYSEYSLATCNSSLDIKLLXSIV 639
+ E F++++ LV +Y+ + C + K++ V
Sbjct: 137 KLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVMEGTV 177
>CR541960-1|CAG46758.1| 450|Homo sapiens CSK protein.
Length = 450
Score = 53.6 bits (123), Expect = 9e-07
Identities = 29/101 (28%), Positives = 48/101 (47%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEG 516
L W+ G ITR++A L G FLVR ++N YTL V G + +I +H
Sbjct: 77 LSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHAS 136
Query: 517 RYGFREPFEFKSVVDLVCYYSEYSLATCNSSLDIKLLXSIV 639
+ E F++++ LV +Y+ + C + K++ V
Sbjct: 137 KLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVMEGTV 177
>BC106073-1|AAI06074.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 53.6 bits (123), Expect = 9e-07
Identities = 29/101 (28%), Positives = 48/101 (47%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEG 516
L W+ G ITR++A L G FLVR ++N YTL V G + +I +H
Sbjct: 77 LSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHAS 136
Query: 517 RYGFREPFEFKSVVDLVCYYSEYSLATCNSSLDIKLLXSIV 639
+ E F++++ LV +Y+ + C + K++ V
Sbjct: 137 KLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVMEGTV 177
>BC104875-1|AAI04876.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 53.6 bits (123), Expect = 9e-07
Identities = 29/101 (28%), Positives = 48/101 (47%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEG 516
L W+ G ITR++A L G FLVR ++N YTL V G + +I +H
Sbjct: 77 LSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHAS 136
Query: 517 RYGFREPFEFKSVVDLVCYYSEYSLATCNSSLDIKLLXSIV 639
+ E F++++ LV +Y+ + C + K++ V
Sbjct: 137 KLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVMEGTV 177
>BC104847-1|AAI04848.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 53.6 bits (123), Expect = 9e-07
Identities = 29/101 (28%), Positives = 48/101 (47%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEG 516
L W+ G ITR++A L G FLVR ++N YTL V G + +I +H
Sbjct: 77 LSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHAS 136
Query: 517 RYGFREPFEFKSVVDLVCYYSEYSLATCNSSLDIKLLXSIV 639
+ E F++++ LV +Y+ + C + K++ V
Sbjct: 137 KLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVMEGTV 177
>AK223626-1|BAD97346.1| 449|Homo sapiens c-src tyrosine kinase
variant protein.
Length = 449
Score = 53.6 bits (123), Expect = 9e-07
Identities = 29/101 (28%), Positives = 48/101 (47%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEG 516
L W+ G ITR++A L G FLVR ++N YTL V G + +I +H
Sbjct: 77 LSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHAS 136
Query: 517 RYGFREPFEFKSVVDLVCYYSEYSLATCNSSLDIKLLXSIV 639
+ E F++++ LV +Y+ + C + K++ V
Sbjct: 137 KLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVMEGTV 177
>M19722-1|AAA52451.1| 529|Homo sapiens FGR protein.
Length = 529
Score = 50.8 bits (116), Expect = 6e-06
Identities = 30/102 (29%), Positives = 49/102 (48%), Gaps = 8/102 (7%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRD--TRDGTFLVRNASNKDSGYTLTVRKGGANKLI 495
+P S++A EWY+G I R +A +L G FL+R + Y+L++R +
Sbjct: 134 APVDSIQAEEWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRDWDQTRGD 193
Query: 496 KIYHHE------GRYGFREPFEFKSVVDLVCYYSEYSLATCN 603
+ H++ G Y +F SV +LV +Y E + CN
Sbjct: 194 HVKHYKIRKLDMGGYYITTRVQFNSVQELVQHYMEVNDGLCN 235
>M12724-1|AAA52762.1| 306|Homo sapiens FGR protein.
Length = 306
Score = 50.8 bits (116), Expect = 6e-06
Identities = 30/102 (29%), Positives = 49/102 (48%), Gaps = 8/102 (7%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRD--TRDGTFLVRNASNKDSGYTLTVRKGGANKLI 495
+P S++A EWY+G I R +A +L G FL+R + Y+L++R +
Sbjct: 24 APVDSIQAEEWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRDWDQTRGD 83
Query: 496 KIYHHE------GRYGFREPFEFKSVVDLVCYYSEYSLATCN 603
+ H++ G Y +F SV +LV +Y E + CN
Sbjct: 84 HVKHYKIRKLDMGGYYITTRVQFNSVQELVQHYMEVNDGLCN 125
>BC064382-1|AAH64382.1| 529|Homo sapiens Gardner-Rasheed feline
sarcoma viral (v-fgr) oncogene homolog protein.
Length = 529
Score = 50.8 bits (116), Expect = 6e-06
Identities = 30/102 (29%), Positives = 49/102 (48%), Gaps = 8/102 (7%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRD--TRDGTFLVRNASNKDSGYTLTVRKGGANKLI 495
+P S++A EWY+G I R +A +L G FL+R + Y+L++R +
Sbjct: 134 APVDSIQAEEWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRDWDQTRGD 193
Query: 496 KIYHHE------GRYGFREPFEFKSVVDLVCYYSEYSLATCN 603
+ H++ G Y +F SV +LV +Y E + CN
Sbjct: 194 HVKHYKIRKLDMGGYYITTRVQFNSVQELVQHYMEVNDGLCN 235
>AL031729-3|CAB62998.1| 529|Homo sapiens Gardner-Rasheed feline
sarcoma viral (v-fgr) oncogene homolog protein.
Length = 529
Score = 50.8 bits (116), Expect = 6e-06
Identities = 30/102 (29%), Positives = 49/102 (48%), Gaps = 8/102 (7%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRD--TRDGTFLVRNASNKDSGYTLTVRKGGANKLI 495
+P S++A EWY+G I R +A +L G FL+R + Y+L++R +
Sbjct: 134 APVDSIQAEEWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRDWDQTRGD 193
Query: 496 KIYHHE------GRYGFREPFEFKSVVDLVCYYSEYSLATCN 603
+ H++ G Y +F SV +LV +Y E + CN
Sbjct: 194 HVKHYKIRKLDMGGYYITTRVQFNSVQELVQHYMEVNDGLCN 235
>AL031729-2|CAI19617.1| 313|Homo sapiens Gardner-Rasheed feline
sarcoma viral (v-fgr) oncogene homolog protein.
Length = 313
Score = 50.8 bits (116), Expect = 6e-06
Identities = 30/102 (29%), Positives = 49/102 (48%), Gaps = 8/102 (7%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRD--TRDGTFLVRNASNKDSGYTLTVRKGGANKLI 495
+P S++A EWY+G I R +A +L G FL+R + Y+L++R +
Sbjct: 134 APVDSIQAEEWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRDWDQTRGD 193
Query: 496 KIYHHE------GRYGFREPFEFKSVVDLVCYYSEYSLATCN 603
+ H++ G Y +F SV +LV +Y E + CN
Sbjct: 194 HVKHYKIRKLDMGGYYITTRVQFNSVQELVQHYMEVNDGLCN 235
>X77278-1|CAA54493.1| 507|Homo sapiens HYL tyrosine kinase protein.
Length = 507
Score = 50.4 bits (115), Expect = 9e-06
Identities = 28/93 (30%), Positives = 45/93 (48%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
S + L W+ G I+ EA ++L+ DG FLVR ++ Y L V G ++
Sbjct: 112 SADPKLSLMPWFHGKISGQEAVQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRV 171
Query: 502 YHHEGRYGFREPFEFKSVVDLVCYYSEYSLATC 600
H +G E F +++D+V +YS+ A C
Sbjct: 172 LHRDGHLTIDEAVFFCNLMDMVEHYSKDKGAIC 204
>S75164-1|AAC60645.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 50.4 bits (115), Expect = 9e-06
Identities = 28/93 (30%), Positives = 45/93 (48%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
S + L W+ G I+ EA ++L+ DG FLVR ++ Y L V G ++
Sbjct: 112 SADPKLSLMPWFHGKISGQEAVQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRV 171
Query: 502 YHHEGRYGFREPFEFKSVVDLVCYYSEYSLATC 600
H +G E F +++D+V +YS+ A C
Sbjct: 172 LHRDGHLTIDEAVFFCNLMDMVEHYSKDKGAIC 204
>L18974-1|AAA16703.1| 527|Homo sapiens tyrosine kinase protein.
Length = 527
Score = 50.4 bits (115), Expect = 9e-06
Identities = 28/93 (30%), Positives = 45/93 (48%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
S + L W+ G I+ EA ++L+ DG FLVR ++ Y L V G ++
Sbjct: 112 SADPKLSLMPWFHGKISGQEAVQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRV 171
Query: 502 YHHEGRYGFREPFEFKSVVDLVCYYSEYSLATC 600
H +G E F +++D+V +YS+ A C
Sbjct: 172 LHRDGHLTIDEAVFFCNLMDMVEHYSKDKGAIC 204
>BC003109-1|AAH03109.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 50.4 bits (115), Expect = 9e-06
Identities = 28/93 (30%), Positives = 45/93 (48%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
S + L W+ G I+ EA ++L+ DG FLVR ++ Y L V G ++
Sbjct: 112 SADPKLSLMPWFHGKISGQEAVQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRV 171
Query: 502 YHHEGRYGFREPFEFKSVVDLVCYYSEYSLATC 600
H +G E F +++D+V +YS+ A C
Sbjct: 172 LHRDGHLTIDEAVFFCNLMDMVEHYSKDKGAIC 204
>BC000114-1|AAH00114.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 50.4 bits (115), Expect = 9e-06
Identities = 28/93 (30%), Positives = 45/93 (48%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
S + L W+ G I+ EA ++L+ DG FLVR ++ Y L V G ++
Sbjct: 112 SADPKLSLMPWFHGKISGQEAVQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRV 171
Query: 502 YHHEGRYGFREPFEFKSVVDLVCYYSEYSLATC 600
H +G E F +++D+V +YS+ A C
Sbjct: 172 LHRDGHLTIDEAVFFCNLMDMVEHYSKDKGAIC 204
>AC005777-1|AAC62843.1| 507|Homo sapiens MATK_HUMAN protein.
Length = 507
Score = 50.4 bits (115), Expect = 9e-06
Identities = 28/93 (30%), Positives = 45/93 (48%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
S + L W+ G I+ EA ++L+ DG FLVR ++ Y L V G ++
Sbjct: 112 SADPKLSLMPWFHGKISGQEAVQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRV 171
Query: 502 YHHEGRYGFREPFEFKSVVDLVCYYSEYSLATC 600
H +G E F +++D+V +YS+ A C
Sbjct: 172 LHRDGHLTIDEAVFFCNLMDMVEHYSKDKGAIC 204
>S71669-1|AAB30995.1| 465|Homo sapiens lsk protein.
Length = 465
Score = 50.0 bits (114), Expect = 1e-05
Identities = 28/93 (30%), Positives = 44/93 (47%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
S + L W+ G I+ EA ++L+ DG FLVR + Y L V G ++
Sbjct: 71 SADPKLSLMPWFHGKISGQEAVQQLQPPEDGLFLVRESGGHPGDYVLCVTFGRDVIHYRV 130
Query: 502 YHHEGRYGFREPFEFKSVVDLVCYYSEYSLATC 600
H +G E F +++D+V +YS+ A C
Sbjct: 131 LHRDGHLTIDEAVFFCNLMDMVEHYSKDKGAIC 163
>Z97989-4|CAI22300.1| 537|Homo sapiens FYN oncogene related to SRC,
FGR, YES protein.
Length = 537
Score = 49.2 bits (112), Expect = 2e-05
Identities = 32/101 (31%), Positives = 51/101 (50%), Gaps = 8/101 (7%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRD--GTFLVRNASNKDSGYTLTVR-----KGG 480
+P S++A EWY+G + R +A +L + GTFL+R + Y+L++R KG
Sbjct: 139 APVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGD 198
Query: 481 ANKLIKIYH-HEGRYGFREPFEFKSVVDLVCYYSEYSLATC 600
K KI G Y +F+++ LV +YSE + C
Sbjct: 199 HVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLC 239
>M14676-1|AAA36615.1| 537|Homo sapiens protein ( Human src-like
kinase (slk) mRNA, complete cds. ).
Length = 537
Score = 49.2 bits (112), Expect = 2e-05
Identities = 32/101 (31%), Positives = 51/101 (50%), Gaps = 8/101 (7%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRD--GTFLVRNASNKDSGYTLTVR-----KGG 480
+P S++A EWY+G + R +A +L + GTFL+R + Y+L++R KG
Sbjct: 139 APVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGSYSLSIRDWDDMKGD 198
Query: 481 ANKLIKIYH-HEGRYGFREPFEFKSVVDLVCYYSEYSLATC 600
K KI G Y +F+++ LV +YSE + C
Sbjct: 199 HVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLC 239
>M14333-1|AAC08285.1| 537|Homo sapiens protein ( Homo sapiens c-syn
protooncogene mRNA, complete cds. ).
Length = 537
Score = 49.2 bits (112), Expect = 2e-05
Identities = 32/101 (31%), Positives = 51/101 (50%), Gaps = 8/101 (7%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRD--GTFLVRNASNKDSGYTLTVR-----KGG 480
+P S++A EWY+G + R +A +L + GTFL+R + Y+L++R KG
Sbjct: 139 APVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGD 198
Query: 481 ANKLIKIYH-HEGRYGFREPFEFKSVVDLVCYYSEYSLATC 600
K KI G Y +F+++ LV +YSE + C
Sbjct: 199 HVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLC 239
>Z97989-5|CAI22301.1| 534|Homo sapiens FYN oncogene related to SRC,
FGR, YES protein.
Length = 534
Score = 48.0 bits (109), Expect = 5e-05
Identities = 32/101 (31%), Positives = 51/101 (50%), Gaps = 8/101 (7%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRD--GTFLVRNASNKDSGYTLTVR-----KGG 480
+P S++A EWY+G + R +A +L + GTFL+R + Y+L++R KG
Sbjct: 139 APVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGD 198
Query: 481 ANKLIKIYH-HEGRYGFREPFEFKSVVDLVCYYSEYSLATC 600
K KI G Y +F+++ LV +YSE + C
Sbjct: 199 HVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSEKADGLC 239
>Z46940-6|CAB92528.1| 211|Homo sapiens suppressor of cytokine
signalling protein protein.
Length = 211
Score = 48.0 bits (109), Expect = 5e-05
Identities = 24/72 (33%), Positives = 42/72 (58%), Gaps = 3/72 (4%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEG 516
L+A +YWG ++ A+E+LR GTFLVR++ ++ + L+V+ I+++ G
Sbjct: 74 LDACGFYWGPLSVHGAHERLRAEPVGTFLVRDSRQRNCFFALSVKMASGPTSIRVHFQAG 133
Query: 517 RY---GFREPFE 543
R+ G RE F+
Sbjct: 134 RFHLDGSRESFD 145
>U88326-1|AAB62401.1| 211|Homo sapiens suppressor of cytokine
signalling-1 protein.
Length = 211
Score = 48.0 bits (109), Expect = 5e-05
Identities = 24/72 (33%), Positives = 42/72 (58%), Gaps = 3/72 (4%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEG 516
L+A +YWG ++ A+E+LR GTFLVR++ ++ + L+V+ I+++ G
Sbjct: 74 LDACGFYWGPLSVHGAHERLRAEPVGTFLVRDSRQRNCFFALSVKMASGPTSIRVHFQAG 133
Query: 517 RY---GFREPFE 543
R+ G RE F+
Sbjct: 134 RFHLDGSRESFD 145
>S74774-1|AAB33113.2| 534|Homo sapiens tyrosine kinase p59fyn(T)
protein.
Length = 534
Score = 48.0 bits (109), Expect = 5e-05
Identities = 32/101 (31%), Positives = 51/101 (50%), Gaps = 8/101 (7%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRD--GTFLVRNASNKDSGYTLTVR-----KGG 480
+P S++A EWY+G + R +A +L + GTFL+R + Y+L++R KG
Sbjct: 139 APVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGD 198
Query: 481 ANKLIKIYH-HEGRYGFREPFEFKSVVDLVCYYSEYSLATC 600
K KI G Y +F+++ LV +YSE + C
Sbjct: 199 HVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSEKADGLC 239
>DQ086801-1|AAY87931.1| 211|Homo sapiens suppressor of cytokine
signaling 1 protein.
Length = 211
Score = 48.0 bits (109), Expect = 5e-05
Identities = 24/72 (33%), Positives = 42/72 (58%), Gaps = 3/72 (4%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEG 516
L+A +YWG ++ A+E+LR GTFLVR++ ++ + L+V+ I+++ G
Sbjct: 74 LDACGFYWGPLSVHGAHERLRAEPVGTFLVRDSRQRNCFFALSVKMASGPTSIRVHFQAG 133
Query: 517 RY---GFREPFE 543
R+ G RE F+
Sbjct: 134 RFHLDGSRESFD 145
>AF132440-1|AAD27709.1| 211|Homo sapiens suppressor of cytokine
signalling-1 SOCS-1 protein.
Length = 211
Score = 48.0 bits (109), Expect = 5e-05
Identities = 24/72 (33%), Positives = 42/72 (58%), Gaps = 3/72 (4%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEG 516
L+A +YWG ++ A+E+LR GTFLVR++ ++ + L+V+ I+++ G
Sbjct: 74 LDACGFYWGPLSVHGAHERLRAEPVGTFLVRDSRQRNCFFALSVKMASGPTSIRVHFQAG 133
Query: 517 RY---GFREPFE 543
R+ G RE F+
Sbjct: 134 RFHLDGSRESFD 145
>AB005043-1|BAA22431.1| 211|Homo sapiens STAT induced STAT
inhibitor-1 protein.
Length = 211
Score = 48.0 bits (109), Expect = 5e-05
Identities = 24/72 (33%), Positives = 42/72 (58%), Gaps = 3/72 (4%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEG 516
L+A +YWG ++ A+E+LR GTFLVR++ ++ + L+V+ I+++ G
Sbjct: 74 LDACGFYWGPLSVHGAHERLRAEPVGTFLVRDSRQRNCFFALSVKMASGPTSIRVHFQAG 133
Query: 517 RY---GFREPFE 543
R+ G RE F+
Sbjct: 134 RFHLDGSRESFD 145
>AB000734-1|BAA23521.1| 211|Homo sapiens TIP3 protein.
Length = 211
Score = 48.0 bits (109), Expect = 5e-05
Identities = 24/72 (33%), Positives = 42/72 (58%), Gaps = 3/72 (4%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEG 516
L+A +YWG ++ A+E+LR GTFLVR++ ++ + L+V+ I+++ G
Sbjct: 74 LDACGFYWGPLSVHGAHERLRAEPVGTFLVRDSRQRNCFFALSVKMASGPTSIRVHFQAG 133
Query: 517 RY---GFREPFE 543
R+ G RE F+
Sbjct: 134 RFHLDGSRESFD 145
>AB000676-1|BAA21537.1| 197|Homo sapiens JAB protein.
Length = 197
Score = 48.0 bits (109), Expect = 5e-05
Identities = 24/72 (33%), Positives = 42/72 (58%), Gaps = 3/72 (4%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEG 516
L+A +YWG ++ A+E+LR GTFLVR++ ++ + L+V+ I+++ G
Sbjct: 60 LDACGFYWGPLSVHGAHERLRAEPVGTFLVRDSRQRNCFFALSVKMASGPTSIRVHFQAG 119
Query: 517 RY---GFREPFE 543
R+ G RE F+
Sbjct: 120 RFHLDGSRESFD 131
>BC117210-1|AAI17211.1| 495|Homo sapiens Src homology 2 domain
containing E protein.
Length = 495
Score = 47.6 bits (108), Expect = 6e-05
Identities = 27/91 (29%), Positives = 47/91 (51%), Gaps = 2/91 (2%)
Frame = +1
Query: 325 PEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKG-GANKLIKI 501
P LE WY G I+R EA +L+ ++ +LVRN+ + +S Y++ ++ G +I
Sbjct: 386 PGLPLEKQPWYHGAISRAEAESRLQPCKEAGYLVRNSESGNSRYSIALKTSQGCVHIIVA 445
Query: 502 YHHEGRYGFREPFE-FKSVVDLVCYYSEYSL 591
+ +Y + F S+ ++V YYS L
Sbjct: 446 QTKDNKYTLNQTSAVFDSIPEVVHYYSNEKL 476
>AL162591-2|CAH72851.1| 495|Homo sapiens Src homology 2 domain
containing E protein.
Length = 495
Score = 47.6 bits (108), Expect = 6e-05
Identities = 27/91 (29%), Positives = 47/91 (51%), Gaps = 2/91 (2%)
Frame = +1
Query: 325 PEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKG-GANKLIKI 501
P LE WY G I+R EA +L+ ++ +LVRN+ + +S Y++ ++ G +I
Sbjct: 386 PGLPLEKQPWYHGAISRAEAESRLQPCKEAGYLVRNSESGNSRYSIALKTSQGCVHIIVA 445
Query: 502 YHHEGRYGFREPFE-FKSVVDLVCYYSEYSL 591
+ +Y + F S+ ++V YYS L
Sbjct: 446 QTKDNKYTLNQTSAVFDSIPEVVHYYSNEKL 476
>AK074067-1|BAB84893.1| 309|Homo sapiens FLJ00138 protein protein.
Length = 309
Score = 47.6 bits (108), Expect = 6e-05
Identities = 27/91 (29%), Positives = 47/91 (51%), Gaps = 2/91 (2%)
Frame = +1
Query: 325 PEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKG-GANKLIKI 501
P LE WY G I+R EA +L+ ++ +LVRN+ + +S Y++ ++ G +I
Sbjct: 200 PGLPLEKQPWYHGAISRAEAESRLQPCKEAGYLVRNSESGNSRYSIALKTSQGCVHIIVA 259
Query: 502 YHHEGRYGFREPFE-FKSVVDLVCYYSEYSL 591
+ +Y + F S+ ++V YYS L
Sbjct: 260 QTKDNKYTLNQTSAVFDSIPEVVHYYSNEKL 290
>BC128607-1|AAI28608.1| 440|Homo sapiens SOCS7 protein protein.
Length = 440
Score = 47.2 bits (107), Expect = 8e-05
Identities = 21/62 (33%), Positives = 35/62 (56%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEG 516
LE WYWG + ++A KL+ DG+FLVR++S+ +L+ R G ++ H+ G
Sbjct: 254 LEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRG 313
Query: 517 RY 522
+
Sbjct: 314 TF 315
>AB005216-1|BAA22432.1| 485|Homo sapiens Nck, Ash and phospholipase
C gamma-binding protein NAP4 protein.
Length = 485
Score = 47.2 bits (107), Expect = 8e-05
Identities = 21/62 (33%), Positives = 35/62 (56%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEG 516
LE WYWG + ++A KL+ DG+FLVR++S+ +L+ R G ++ H+ G
Sbjct: 272 LEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRG 331
Query: 517 RY 522
+
Sbjct: 332 TF 333
>X78549-1|CAA55295.1| 451|Homo sapiens tyrosine kinase protein.
Length = 451
Score = 46.8 bits (106), Expect = 1e-04
Identities = 29/90 (32%), Positives = 47/90 (52%), Gaps = 3/90 (3%)
Frame = +1
Query: 334 SLEAAEWYWGDITRDEANEKLR--DTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYH 507
++E+ W++G I+R EA +L+ G FL+R + + Y L+VR A + KI+
Sbjct: 72 TVESEPWFFGCISRSEAVRRLQAEGNATGAFLIRVSEKPSADYVLSVRDTQAVRHYKIWR 131
Query: 508 HE-GRYGFREPFEFKSVVDLVCYYSEYSLA 594
GR E F S+ +LV Y+ SL+
Sbjct: 132 RAGGRLHLNEAVSFLSLPELVNYHRAQSLS 161
>U61412-1|AAC34935.1| 451|Homo sapiens non-receptor type protein
tyrosine kinase protein.
Length = 451
Score = 46.8 bits (106), Expect = 1e-04
Identities = 29/90 (32%), Positives = 47/90 (52%), Gaps = 3/90 (3%)
Frame = +1
Query: 334 SLEAAEWYWGDITRDEANEKLR--DTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYH 507
++E+ W++G I+R EA +L+ G FL+R + + Y L+VR A + KI+
Sbjct: 72 TVESEPWFFGCISRSEAVRRLQAEGNATGAFLIRVSEKPSADYVLSVRDTQAVRHYKIWR 131
Query: 508 HE-GRYGFREPFEFKSVVDLVCYYSEYSLA 594
GR E F S+ +LV Y+ SL+
Sbjct: 132 RAGGRLHLNEAVSFLSLPELVNYHRAQSLS 161
>S76992-1|AAB34377.1| 878|Homo sapiens VAV2 protein.
Length = 878
Score = 46.8 bits (106), Expect = 1e-04
Identities = 35/134 (26%), Positives = 60/134 (44%), Gaps = 3/134 (2%)
Frame = +1
Query: 232 RVVKQRKLDNYTAPSSPDDEIMVEIGVPQQSP---EHSLEAAEWYWGDITRDEANEKLRD 402
R+V+ RK + PSS V+ P P E A W+ G++ R + + L+
Sbjct: 632 RLVQTRKSGYF--PSSSVKPCPVDGRPPISRPPSREIDYTAYPWFAGNMERQQTDNLLKS 689
Query: 403 TRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSE 582
GT+L+R + + ++++ K IK+ + E +F S+++LV YY
Sbjct: 690 HASGTYLIRERPAEAERFAISIKFNDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQC 749
Query: 583 YSLATCNSSLDIKL 624
+SL LD L
Sbjct: 750 HSLKESFKQLDTTL 763
>BX640754-1|CAE45861.1| 801|Homo sapiens hypothetical protein
protein.
Length = 801
Score = 46.8 bits (106), Expect = 1e-04
Identities = 35/134 (26%), Positives = 60/134 (44%), Gaps = 3/134 (2%)
Frame = +1
Query: 232 RVVKQRKLDNYTAPSSPDDEIMVEIGVPQQSP---EHSLEAAEWYWGDITRDEANEKLRD 402
R+V+ RK + PSS V+ P P E A W+ G++ R + + L+
Sbjct: 584 RLVQTRKSGYF--PSSSVKPCPVDGRPPISRPPSREIDYTAYPWFAGNMERQQTDNLLKS 641
Query: 403 TRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSE 582
GT+L+R + + ++++ K IK+ + E +F S+++LV YY
Sbjct: 642 HASGTYLIRERPAEAERFAISIKFNDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQC 701
Query: 583 YSLATCNSSLDIKL 624
+SL LD L
Sbjct: 702 HSLKESFKQLDTTL 715
>BC132967-1|AAI32968.1| 839|Homo sapiens vav 2 guanine nucleotide
exchange factor protein.
Length = 839
Score = 46.8 bits (106), Expect = 1e-04
Identities = 35/134 (26%), Positives = 60/134 (44%), Gaps = 3/134 (2%)
Frame = +1
Query: 232 RVVKQRKLDNYTAPSSPDDEIMVEIGVPQQSP---EHSLEAAEWYWGDITRDEANEKLRD 402
R+V+ RK + PSS V+ P P E A W+ G++ R + + L+
Sbjct: 622 RLVQTRKSGYF--PSSSVKPCPVDGRPPISRPPSREIDYTAYPWFAGNMERQQTDNLLKS 679
Query: 403 TRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSE 582
GT+L+R + + ++++ K IK+ + E +F S+++LV YY
Sbjct: 680 HASGTYLIRERPAEAERFAISIKFNDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQC 739
Query: 583 YSLATCNSSLDIKL 624
+SL LD L
Sbjct: 740 HSLKESFKQLDTTL 753
>BC132965-1|AAI32966.1| 839|Homo sapiens vav 2 guanine nucleotide
exchange factor protein.
Length = 839
Score = 46.8 bits (106), Expect = 1e-04
Identities = 35/134 (26%), Positives = 60/134 (44%), Gaps = 3/134 (2%)
Frame = +1
Query: 232 RVVKQRKLDNYTAPSSPDDEIMVEIGVPQQSP---EHSLEAAEWYWGDITRDEANEKLRD 402
R+V+ RK + PSS V+ P P E A W+ G++ R + + L+
Sbjct: 622 RLVQTRKSGYF--PSSSVKPCPVDGRPPISRPPSREIDYTAYPWFAGNMERQQTDNLLKS 679
Query: 403 TRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSE 582
GT+L+R + + ++++ K IK+ + E +F S+++LV YY
Sbjct: 680 HASGTYLIRERPAEAERFAISIKFNDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQC 739
Query: 583 YSLATCNSSLDIKL 624
+SL LD L
Sbjct: 740 HSLKESFKQLDTTL 753
>BC128448-1|AAI28449.1| 474|Homo sapiens VAV2 protein protein.
Length = 474
Score = 46.8 bits (106), Expect = 1e-04
Identities = 35/134 (26%), Positives = 60/134 (44%), Gaps = 3/134 (2%)
Frame = +1
Query: 232 RVVKQRKLDNYTAPSSPDDEIMVEIGVPQQSP---EHSLEAAEWYWGDITRDEANEKLRD 402
R+V+ RK + PSS V+ P P E A W+ G++ R + + L+
Sbjct: 257 RLVQTRKSGYF--PSSSVKPCPVDGRPPISRPPSREIDYTAYPWFAGNMERQQTDNLLKS 314
Query: 403 TRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSE 582
GT+L+R + + ++++ K IK+ + E +F S+++LV YY
Sbjct: 315 HASGTYLIRERPAEAERFAISIKFNDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQC 374
Query: 583 YSLATCNSSLDIKL 624
+SL LD L
Sbjct: 375 HSLKESFKQLDTTL 388
>BC035843-1|AAH35843.1| 451|Homo sapiens PTK6 protein tyrosine
kinase 6 protein.
Length = 451
Score = 46.8 bits (106), Expect = 1e-04
Identities = 29/90 (32%), Positives = 47/90 (52%), Gaps = 3/90 (3%)
Frame = +1
Query: 334 SLEAAEWYWGDITRDEANEKLR--DTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYH 507
++E+ W++G I+R EA +L+ G FL+R + + Y L+VR A + KI+
Sbjct: 72 TVESEPWFFGCISRSEAVRRLQAEGNATGAFLIRVSEKPSADYVLSVRDTQAVRHYKIWR 131
Query: 508 HE-GRYGFREPFEFKSVVDLVCYYSEYSLA 594
GR E F S+ +LV Y+ SL+
Sbjct: 132 RAGGRLHLNEAVSFLSLPELVNYHRAQSLS 161
>BC033187-1|AAH33187.1| 369|Homo sapiens VAV2 protein protein.
Length = 369
Score = 46.8 bits (106), Expect = 1e-04
Identities = 35/134 (26%), Positives = 60/134 (44%), Gaps = 3/134 (2%)
Frame = +1
Query: 232 RVVKQRKLDNYTAPSSPDDEIMVEIGVPQQSP---EHSLEAAEWYWGDITRDEANEKLRD 402
R+V+ RK + PSS V+ P P E A W+ G++ R + + L+
Sbjct: 152 RLVQTRKSGYF--PSSSVKPCPVDGRPPISRPPSREIDYTAYPWFAGNMERQQTDNLLKS 209
Query: 403 TRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSE 582
GT+L+R + + ++++ K IK+ + E +F S+++LV YY
Sbjct: 210 HASGTYLIRERPAEAERFAISIKFNDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQC 269
Query: 583 YSLATCNSSLDIKL 624
+SL LD L
Sbjct: 270 HSLKESFKQLDTTL 283
>AL590710-7|CAI12280.1| 839|Homo sapiens vav 2 oncogene protein.
Length = 839
Score = 46.8 bits (106), Expect = 1e-04
Identities = 35/134 (26%), Positives = 60/134 (44%), Gaps = 3/134 (2%)
Frame = +1
Query: 232 RVVKQRKLDNYTAPSSPDDEIMVEIGVPQQSP---EHSLEAAEWYWGDITRDEANEKLRD 402
R+V+ RK + PSS V+ P P E A W+ G++ R + + L+
Sbjct: 622 RLVQTRKSGYF--PSSSVKPCPVDGRPPISRPPSREIDYTAYPWFAGNMERQQTDNLLKS 679
Query: 403 TRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSE 582
GT+L+R + + ++++ K IK+ + E +F S+++LV YY
Sbjct: 680 HASGTYLIRERPAEAERFAISIKFNDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQC 739
Query: 583 YSLATCNSSLDIKL 624
+SL LD L
Sbjct: 740 HSLKESFKQLDTTL 753
>AL590710-6|CAI12278.1| 868|Homo sapiens vav 2 oncogene protein.
Length = 868
Score = 46.8 bits (106), Expect = 1e-04
Identities = 35/134 (26%), Positives = 60/134 (44%), Gaps = 3/134 (2%)
Frame = +1
Query: 232 RVVKQRKLDNYTAPSSPDDEIMVEIGVPQQSP---EHSLEAAEWYWGDITRDEANEKLRD 402
R+V+ RK + PSS V+ P P E A W+ G++ R + + L+
Sbjct: 622 RLVQTRKSGYF--PSSSVKPCPVDGRPPISRPPSREIDYTAYPWFAGNMERQQTDNLLKS 679
Query: 403 TRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSE 582
GT+L+R + + ++++ K IK+ + E +F S+++LV YY
Sbjct: 680 HASGTYLIRERPAEAERFAISIKFNDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQC 739
Query: 583 YSLATCNSSLDIKL 624
+SL LD L
Sbjct: 740 HSLKESFKQLDTTL 753
>AL590710-5|CAI12279.1| 878|Homo sapiens vav 2 oncogene protein.
Length = 878
Score = 46.8 bits (106), Expect = 1e-04
Identities = 35/134 (26%), Positives = 60/134 (44%), Gaps = 3/134 (2%)
Frame = +1
Query: 232 RVVKQRKLDNYTAPSSPDDEIMVEIGVPQQSP---EHSLEAAEWYWGDITRDEANEKLRD 402
R+V+ RK + PSS V+ P P E A W+ G++ R + + L+
Sbjct: 632 RLVQTRKSGYF--PSSSVKPCPVDGRPPISRPPSREIDYTAYPWFAGNMERQQTDNLLKS 689
Query: 403 TRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSE 582
GT+L+R + + ++++ K IK+ + E +F S+++LV YY
Sbjct: 690 HASGTYLIRERPAEAERFAISIKFNDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQC 749
Query: 583 YSLATCNSSLDIKL 624
+SL LD L
Sbjct: 750 HSLKESFKQLDTTL 763
>AL445931-3|CAI13724.1| 839|Homo sapiens vav 2 oncogene protein.
Length = 839
Score = 46.8 bits (106), Expect = 1e-04
Identities = 35/134 (26%), Positives = 60/134 (44%), Gaps = 3/134 (2%)
Frame = +1
Query: 232 RVVKQRKLDNYTAPSSPDDEIMVEIGVPQQSP---EHSLEAAEWYWGDITRDEANEKLRD 402
R+V+ RK + PSS V+ P P E A W+ G++ R + + L+
Sbjct: 622 RLVQTRKSGYF--PSSSVKPCPVDGRPPISRPPSREIDYTAYPWFAGNMERQQTDNLLKS 679
Query: 403 TRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSE 582
GT+L+R + + ++++ K IK+ + E +F S+++LV YY
Sbjct: 680 HASGTYLIRERPAEAERFAISIKFNDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQC 739
Query: 583 YSLATCNSSLDIKL 624
+SL LD L
Sbjct: 740 HSLKESFKQLDTTL 753
>AL445931-2|CAI13723.1| 868|Homo sapiens vav 2 oncogene protein.
Length = 868
Score = 46.8 bits (106), Expect = 1e-04
Identities = 35/134 (26%), Positives = 60/134 (44%), Gaps = 3/134 (2%)
Frame = +1
Query: 232 RVVKQRKLDNYTAPSSPDDEIMVEIGVPQQSP---EHSLEAAEWYWGDITRDEANEKLRD 402
R+V+ RK + PSS V+ P P E A W+ G++ R + + L+
Sbjct: 622 RLVQTRKSGYF--PSSSVKPCPVDGRPPISRPPSREIDYTAYPWFAGNMERQQTDNLLKS 679
Query: 403 TRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSE 582
GT+L+R + + ++++ K IK+ + E +F S+++LV YY
Sbjct: 680 HASGTYLIRERPAEAERFAISIKFNDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQC 739
Query: 583 YSLATCNSSLDIKL 624
+SL LD L
Sbjct: 740 HSLKESFKQLDTTL 753
>AL445931-1|CAI13722.1| 878|Homo sapiens vav 2 oncogene protein.
Length = 878
Score = 46.8 bits (106), Expect = 1e-04
Identities = 35/134 (26%), Positives = 60/134 (44%), Gaps = 3/134 (2%)
Frame = +1
Query: 232 RVVKQRKLDNYTAPSSPDDEIMVEIGVPQQSP---EHSLEAAEWYWGDITRDEANEKLRD 402
R+V+ RK + PSS V+ P P E A W+ G++ R + + L+
Sbjct: 632 RLVQTRKSGYF--PSSSVKPCPVDGRPPISRPPSREIDYTAYPWFAGNMERQQTDNLLKS 689
Query: 403 TRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSE 582
GT+L+R + + ++++ K IK+ + E +F S+++LV YY
Sbjct: 690 HASGTYLIRERPAEAERFAISIKFNDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQC 749
Query: 583 YSLATCNSSLDIKL 624
+SL LD L
Sbjct: 750 HSLKESFKQLDTTL 763
>AL357934-3|CAI15782.1| 839|Homo sapiens vav 2 oncogene protein.
Length = 839
Score = 46.8 bits (106), Expect = 1e-04
Identities = 35/134 (26%), Positives = 60/134 (44%), Gaps = 3/134 (2%)
Frame = +1
Query: 232 RVVKQRKLDNYTAPSSPDDEIMVEIGVPQQSP---EHSLEAAEWYWGDITRDEANEKLRD 402
R+V+ RK + PSS V+ P P E A W+ G++ R + + L+
Sbjct: 622 RLVQTRKSGYF--PSSSVKPCPVDGRPPISRPPSREIDYTAYPWFAGNMERQQTDNLLKS 679
Query: 403 TRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSE 582
GT+L+R + + ++++ K IK+ + E +F S+++LV YY
Sbjct: 680 HASGTYLIRERPAEAERFAISIKFNDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQC 739
Query: 583 YSLATCNSSLDIKL 624
+SL LD L
Sbjct: 740 HSLKESFKQLDTTL 753
>AL357934-2|CAI15781.1| 868|Homo sapiens vav 2 oncogene protein.
Length = 868
Score = 46.8 bits (106), Expect = 1e-04
Identities = 35/134 (26%), Positives = 60/134 (44%), Gaps = 3/134 (2%)
Frame = +1
Query: 232 RVVKQRKLDNYTAPSSPDDEIMVEIGVPQQSP---EHSLEAAEWYWGDITRDEANEKLRD 402
R+V+ RK + PSS V+ P P E A W+ G++ R + + L+
Sbjct: 622 RLVQTRKSGYF--PSSSVKPCPVDGRPPISRPPSREIDYTAYPWFAGNMERQQTDNLLKS 679
Query: 403 TRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSE 582
GT+L+R + + ++++ K IK+ + E +F S+++LV YY
Sbjct: 680 HASGTYLIRERPAEAERFAISIKFNDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQC 739
Query: 583 YSLATCNSSLDIKL 624
+SL LD L
Sbjct: 740 HSLKESFKQLDTTL 753
>AL357934-1|CAI15783.1| 878|Homo sapiens vav 2 oncogene protein.
Length = 878
Score = 46.8 bits (106), Expect = 1e-04
Identities = 35/134 (26%), Positives = 60/134 (44%), Gaps = 3/134 (2%)
Frame = +1
Query: 232 RVVKQRKLDNYTAPSSPDDEIMVEIGVPQQSP---EHSLEAAEWYWGDITRDEANEKLRD 402
R+V+ RK + PSS V+ P P E A W+ G++ R + + L+
Sbjct: 632 RLVQTRKSGYF--PSSSVKPCPVDGRPPISRPPSREIDYTAYPWFAGNMERQQTDNLLKS 689
Query: 403 TRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSE 582
GT+L+R + + ++++ K IK+ + E +F S+++LV YY
Sbjct: 690 HASGTYLIRERPAEAERFAISIKFNDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQC 749
Query: 583 YSLATCNSSLDIKL 624
+SL LD L
Sbjct: 750 HSLKESFKQLDTTL 763
>AL121829-13|CAC15525.1| 451|Homo sapiens PTK6 protein.
Length = 451
Score = 46.8 bits (106), Expect = 1e-04
Identities = 29/90 (32%), Positives = 47/90 (52%), Gaps = 3/90 (3%)
Frame = +1
Query: 334 SLEAAEWYWGDITRDEANEKLR--DTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYH 507
++E+ W++G I+R EA +L+ G FL+R + + Y L+VR A + KI+
Sbjct: 72 TVESEPWFFGCISRSEAVRRLQAEGNATGAFLIRVSEKPSADYVLSVRDTQAVRHYKIWR 131
Query: 508 HE-GRYGFREPFEFKSVVDLVCYYSEYSLA 594
GR E F S+ +LV Y+ SL+
Sbjct: 132 RAGGRLHLNEAVSFLSLPELVNYHRAQSLS 161
>X70766-1|CAA50045.1| 593|Homo sapiens protein-tyrosine phosphatase
protein.
Length = 593
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/85 (35%), Positives = 46/85 (54%), Gaps = 2/85 (2%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTR--DGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHH 510
+ + W+ +IT EA E L TR DG+FL R + + +TL+VR+ GA IKI +
Sbjct: 1 MTSRRWFHPNITGVEA-ENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNT 59
Query: 511 EGRYGFREPFEFKSVVDLVCYYSEY 585
Y +F ++ +LV YY E+
Sbjct: 60 GDYYDLYGGEKFATLAELVQYYMEH 84
Score = 33.9 bits (74), Expect = 0.80
Identities = 31/121 (25%), Positives = 57/121 (47%), Gaps = 12/121 (9%)
Frame = +1
Query: 295 MVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKLRDT-RDGTFLVRNASNKDSGYTLTVR 471
++E+ P + + E W+ G ++ EA + L + + G+FLVR + + + L+VR
Sbjct: 95 VIELKYPLNCADPTSE--RWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVR 152
Query: 472 KG--------GANKL--IKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSLA-TCNSSLDI 618
G G +K+ + I E +Y F S+ DLV +Y + + T + L +
Sbjct: 153 TGDDKGESNDGKSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQL 212
Query: 619 K 621
K
Sbjct: 213 K 213
>L07527-1|AAA17022.1| 593|Homo sapiens protein-tyrosine phosphatase
protein.
Length = 593
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/85 (35%), Positives = 46/85 (54%), Gaps = 2/85 (2%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTR--DGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHH 510
+ + W+ +IT EA E L TR DG+FL R + + +TL+VR+ GA IKI +
Sbjct: 1 MTSRRWFHPNITGVEA-ENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNT 59
Query: 511 EGRYGFREPFEFKSVVDLVCYYSEY 585
Y +F ++ +LV YY E+
Sbjct: 60 GDYYDLYGGEKFATLAELVQYYMEH 84
Score = 33.9 bits (74), Expect = 0.80
Identities = 31/121 (25%), Positives = 57/121 (47%), Gaps = 12/121 (9%)
Frame = +1
Query: 295 MVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKLRDT-RDGTFLVRNASNKDSGYTLTVR 471
++E+ P + + E W+ G ++ EA + L + + G+FLVR + + + L+VR
Sbjct: 95 VIELKYPLNCADPTSE--RWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVR 152
Query: 472 KG--------GANKL--IKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSLA-TCNSSLDI 618
G G +K+ + I E +Y F S+ DLV +Y + + T + L +
Sbjct: 153 TGDDKGESNDGKSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQL 212
Query: 619 K 621
K
Sbjct: 213 K 213
>L03535-1|AAA36611.1| 593|Homo sapiens phosphotyrosyl-protein
phosphatase protein.
Length = 593
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/85 (35%), Positives = 46/85 (54%), Gaps = 2/85 (2%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTR--DGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHH 510
+ + W+ +IT EA E L TR DG+FL R + + +TL+VR+ GA IKI +
Sbjct: 1 MTSRRWFHPNITGVEA-ENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNT 59
Query: 511 EGRYGFREPFEFKSVVDLVCYYSEY 585
Y +F ++ +LV YY E+
Sbjct: 60 GDYYDLYGGEKFATLAELVQYYMEH 84
Score = 33.9 bits (74), Expect = 0.80
Identities = 31/121 (25%), Positives = 57/121 (47%), Gaps = 12/121 (9%)
Frame = +1
Query: 295 MVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKLRDT-RDGTFLVRNASNKDSGYTLTVR 471
++E+ P + + E W+ G ++ EA + L + + G+FLVR + + + L+VR
Sbjct: 95 VIELKYPLNCADPTSE--RWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVR 152
Query: 472 KG--------GANKL--IKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSLA-TCNSSLDI 618
G G +K+ + I E +Y F S+ DLV +Y + + T + L +
Sbjct: 153 TGDDKGESNDGKSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQL 212
Query: 619 K 621
K
Sbjct: 213 K 213
>D13540-1|BAA02740.2| 593|Homo sapiens protein-tyrosine phosphatase
protein.
Length = 593
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/85 (35%), Positives = 46/85 (54%), Gaps = 2/85 (2%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTR--DGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHH 510
+ + W+ +IT EA E L TR DG+FL R + + +TL+VR+ GA IKI +
Sbjct: 1 MTSRRWFHPNITGVEA-ENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNT 59
Query: 511 EGRYGFREPFEFKSVVDLVCYYSEY 585
Y +F ++ +LV YY E+
Sbjct: 60 GDYYDLYGGEKFATLAELVQYYMEH 84
Score = 33.9 bits (74), Expect = 0.80
Identities = 31/121 (25%), Positives = 57/121 (47%), Gaps = 12/121 (9%)
Frame = +1
Query: 295 MVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKLRDT-RDGTFLVRNASNKDSGYTLTVR 471
++E+ P + + E W+ G ++ EA + L + + G+FLVR + + + L+VR
Sbjct: 95 VIELKYPLNCADPTSE--RWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVR 152
Query: 472 KG--------GANKL--IKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSLA-TCNSSLDI 618
G G +K+ + I E +Y F S+ DLV +Y + + T + L +
Sbjct: 153 TGDDKGESNDGKSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQL 212
Query: 619 K 621
K
Sbjct: 213 K 213
>BT007106-1|AAP35770.1| 460|Homo sapiens protein tyrosine
phosphatase, non-receptor type 11 (Noonan syndrome 1)
protein.
Length = 460
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/85 (35%), Positives = 46/85 (54%), Gaps = 2/85 (2%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTR--DGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHH 510
+ + W+ +IT EA E L TR DG+FL R + + +TL+VR+ GA IKI +
Sbjct: 1 MTSRRWFHPNITGVEA-ENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNT 59
Query: 511 EGRYGFREPFEFKSVVDLVCYYSEY 585
Y +F ++ +LV YY E+
Sbjct: 60 GDYYDLYGGEKFATLAELVQYYMEH 84
Score = 33.9 bits (74), Expect = 0.80
Identities = 31/121 (25%), Positives = 57/121 (47%), Gaps = 12/121 (9%)
Frame = +1
Query: 295 MVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKLRDT-RDGTFLVRNASNKDSGYTLTVR 471
++E+ P + + E W+ G ++ EA + L + + G+FLVR + + + L+VR
Sbjct: 95 VIELKYPLNCADPTSE--RWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVR 152
Query: 472 KG--------GANKL--IKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSLA-TCNSSLDI 618
G G +K+ + I E +Y F S+ DLV +Y + + T + L +
Sbjct: 153 TGDDKGESNDGKSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQL 212
Query: 619 K 621
K
Sbjct: 213 K 213
>BC008692-1|AAH08692.1| 460|Homo sapiens PTPN11 protein protein.
Length = 460
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/85 (35%), Positives = 46/85 (54%), Gaps = 2/85 (2%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTR--DGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHH 510
+ + W+ +IT EA E L TR DG+FL R + + +TL+VR+ GA IKI +
Sbjct: 1 MTSRRWFHPNITGVEA-ENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNT 59
Query: 511 EGRYGFREPFEFKSVVDLVCYYSEY 585
Y +F ++ +LV YY E+
Sbjct: 60 GDYYDLYGGEKFATLAELVQYYMEH 84
Score = 33.9 bits (74), Expect = 0.80
Identities = 31/121 (25%), Positives = 57/121 (47%), Gaps = 12/121 (9%)
Frame = +1
Query: 295 MVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKLRDT-RDGTFLVRNASNKDSGYTLTVR 471
++E+ P + + E W+ G ++ EA + L + + G+FLVR + + + L+VR
Sbjct: 95 VIELKYPLNCADPTSE--RWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVR 152
Query: 472 KG--------GANKL--IKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSLA-TCNSSLDI 618
G G +K+ + I E +Y F S+ DLV +Y + + T + L +
Sbjct: 153 TGDDKGESNDGKSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQL 212
Query: 619 K 621
K
Sbjct: 213 K 213
>D83532-1|BAA92328.1| 258|Homo sapiens cytokine-inducible
SH2-containing protein protein.
Length = 258
Score = 46.0 bits (104), Expect = 2e-04
Identities = 19/45 (42%), Positives = 30/45 (66%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVR 471
L + WYWG IT EA + L+ +GTFLVR++++ +TL+V+
Sbjct: 77 LRESGWYWGSITASEARQHLQKMPEGTFLVRDSTHPSYLFTLSVK 121
>BC064354-1|AAH64354.1| 258|Homo sapiens cytokine inducible
SH2-containing protein protein.
Length = 258
Score = 46.0 bits (104), Expect = 2e-04
Identities = 19/45 (42%), Positives = 30/45 (66%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVR 471
L + WYWG IT EA + L+ +GTFLVR++++ +TL+V+
Sbjct: 77 LRESGWYWGSITASEARQHLQKMPEGTFLVRDSTHPSYLFTLSVK 121
>BC031590-1|AAH31590.1| 258|Homo sapiens cytokine inducible
SH2-containing protein protein.
Length = 258
Score = 46.0 bits (104), Expect = 2e-04
Identities = 19/45 (42%), Positives = 30/45 (66%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVR 471
L + WYWG IT EA + L+ +GTFLVR++++ +TL+V+
Sbjct: 77 LRESGWYWGSITASEARQHLQKMPEGTFLVRDSTHPSYLFTLSVK 121
>AF132297-1|AAD28471.2| 258|Homo sapiens cytokine-inducible
SH2-containing protein protein.
Length = 258
Score = 46.0 bits (104), Expect = 2e-04
Identities = 19/45 (42%), Positives = 30/45 (66%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVR 471
L + WYWG IT EA + L+ +GTFLVR++++ +TL+V+
Sbjct: 77 LRESGWYWGSITASEARQHLQKMPEGTFLVRDSTHPSYLFTLSVK 121
>AF035947-1|AAF97410.1| 264|Homo sapiens cytokine-inducible
inhibitor of signalling type 1b protein.
Length = 264
Score = 46.0 bits (104), Expect = 2e-04
Identities = 19/45 (42%), Positives = 30/45 (66%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVR 471
L + WYWG IT EA + L+ +GTFLVR++++ +TL+V+
Sbjct: 83 LRESGWYWGSITASEARQHLQKMPEGTFLVRDSTHPSYLFTLSVK 127
>AF035946-1|AAQ13420.1| 264|Homo sapiens cytokine-inducible
inhibitor of signalling type IV protein.
Length = 264
Score = 46.0 bits (104), Expect = 2e-04
Identities = 19/45 (42%), Positives = 30/45 (66%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVR 471
L + WYWG IT EA + L+ +GTFLVR++++ +TL+V+
Sbjct: 83 LRESGWYWGSITASEARQHLQKMPEGTFLVRDSTHPSYLFTLSVK 127
>D10656-1|BAA01505.1| 304|Homo sapiens CRK-II protein.
Length = 304
Score = 45.2 bits (102), Expect = 3e-04
Identities = 20/45 (44%), Positives = 27/45 (60%)
Frame = +1
Query: 334 SLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTV 468
S E + WYWG ++R EA L+ R G FLVR++S Y L+V
Sbjct: 7 SEERSSWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSV 51
>BT007277-1|AAP35941.1| 304|Homo sapiens v-crk sarcoma virus CT10
oncogene homolog (avian) protein.
Length = 304
Score = 45.2 bits (102), Expect = 3e-04
Identities = 20/45 (44%), Positives = 27/45 (60%)
Frame = +1
Query: 334 SLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTV 468
S E + WYWG ++R EA L+ R G FLVR++S Y L+V
Sbjct: 7 SEERSSWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSV 51
>BC009837-1|AAH09837.1| 204|Homo sapiens v-crk sarcoma virus CT10
oncogene homolog (avian) protein.
Length = 204
Score = 45.2 bits (102), Expect = 3e-04
Identities = 20/45 (44%), Positives = 27/45 (60%)
Frame = +1
Query: 334 SLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTV 468
S E + WYWG ++R EA L+ R G FLVR++S Y L+V
Sbjct: 7 SEERSSWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSV 51
>BC008506-1|AAH08506.1| 304|Homo sapiens v-crk sarcoma virus CT10
oncogene homolog (avian) protein.
Length = 304
Score = 45.2 bits (102), Expect = 3e-04
Identities = 20/45 (44%), Positives = 27/45 (60%)
Frame = +1
Query: 334 SLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTV 468
S E + WYWG ++R EA L+ R G FLVR++S Y L+V
Sbjct: 7 SEERSSWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSV 51
>BC007195-1|AAH07195.1| 380|Homo sapiens NCK adaptor protein 2
protein.
Length = 380
Score = 45.2 bits (102), Expect = 3e-04
Identities = 24/97 (24%), Positives = 53/97 (54%), Gaps = 1/97 (1%)
Frame = +1
Query: 349 EWYWGDITRDEANEKLRDTR-DGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYG 525
EWY+G++TR +A L + +G FL+R++ + S ++++++ G NK K+ + Y
Sbjct: 284 EWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNKHFKVQLVDNVYC 343
Query: 526 FREPFEFKSVVDLVCYYSEYSLATCNSSLDIKLLXSI 636
+ F ++ +LV +Y + + T + L+ ++
Sbjct: 344 IGQR-RFHTMDELVEHYKKAPIFTSEHGEKLYLVRAL 379
>BC001718-1|AAH01718.1| 304|Homo sapiens v-crk sarcoma virus CT10
oncogene homolog (avian) protein.
Length = 304
Score = 45.2 bits (102), Expect = 3e-04
Identities = 20/45 (44%), Positives = 27/45 (60%)
Frame = +1
Query: 334 SLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTV 468
S E + WYWG ++R EA L+ R G FLVR++S Y L+V
Sbjct: 7 SEERSSWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSV 51
>BC000103-1|AAH00103.1| 380|Homo sapiens NCK adaptor protein 2
protein.
Length = 380
Score = 45.2 bits (102), Expect = 3e-04
Identities = 24/97 (24%), Positives = 53/97 (54%), Gaps = 1/97 (1%)
Frame = +1
Query: 349 EWYWGDITRDEANEKLRDTR-DGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYG 525
EWY+G++TR +A L + +G FL+R++ + S ++++++ G NK K+ + Y
Sbjct: 284 EWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNKHFKVQLVDNVYC 343
Query: 526 FREPFEFKSVVDLVCYYSEYSLATCNSSLDIKLLXSI 636
+ F ++ +LV +Y + + T + L+ ++
Sbjct: 344 IGQR-RFHTMDELVEHYKKAPIFTSEHGEKLYLVRAL 379
>AF047487-1|AAC80284.1| 380|Homo sapiens Nck-2 protein.
Length = 380
Score = 45.2 bits (102), Expect = 3e-04
Identities = 24/97 (24%), Positives = 53/97 (54%), Gaps = 1/97 (1%)
Frame = +1
Query: 349 EWYWGDITRDEANEKLRDTR-DGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYG 525
EWY+G++TR +A L + +G FL+R++ + S ++++++ G NK K+ + Y
Sbjct: 284 EWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNKHFKVQLVDNVYC 343
Query: 526 FREPFEFKSVVDLVCYYSEYSLATCNSSLDIKLLXSI 636
+ F ++ +LV +Y + + T + L+ ++
Sbjct: 344 IGQR-RFHTMDELVEHYKKAPIFTSEHGEKLYLVRAL 379
>AF043119-1|AAC04831.1| 381|Homo sapiens SH2/SH3 adaptor protein
NCK-beta protein.
Length = 381
Score = 45.2 bits (102), Expect = 3e-04
Identities = 24/97 (24%), Positives = 53/97 (54%), Gaps = 1/97 (1%)
Frame = +1
Query: 349 EWYWGDITRDEANEKLRDTR-DGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYG 525
EWY+G++TR +A L + +G FL+R++ + S ++++++ G NK K+ + Y
Sbjct: 285 EWYYGNVTRHQAQCALNERGVEGDFLIRDSESSPSDFSVSLKASGKNKHFKVQLVDNVYC 344
Query: 526 FREPFEFKSVVDLVCYYSEYSLATCNSSLDIKLLXSI 636
+ F ++ +LV +Y + + T + L+ ++
Sbjct: 345 IGQR-RFHTMDELVEHYKKAPIFTSEHGEKLYLVRAL 380
>AC009505-1|AAY24332.1| 304|Homo sapiens unknown protein.
Length = 304
Score = 45.2 bits (102), Expect = 3e-04
Identities = 24/97 (24%), Positives = 53/97 (54%), Gaps = 1/97 (1%)
Frame = +1
Query: 349 EWYWGDITRDEANEKLRDTR-DGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYG 525
EWY+G++TR +A L + +G FL+R++ + S ++++++ G NK K+ + Y
Sbjct: 208 EWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNKHFKVQLVDNVYC 267
Query: 526 FREPFEFKSVVDLVCYYSEYSLATCNSSLDIKLLXSI 636
+ F ++ +LV +Y + + T + L+ ++
Sbjct: 268 IGQR-RFHTMDELVEHYKKAPIFTSEHGEKLYLVRAL 303
>D84361-2|BAA12323.1| 474|Homo sapiens p52 isoform of N-Shc
protein.
Length = 474
Score = 44.8 bits (101), Expect = 4e-04
Identities = 29/104 (27%), Positives = 49/104 (47%)
Frame = +1
Query: 313 PQQSPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKL 492
P L+A WY G+++R EA L +DG FLVR ++ + LT G K
Sbjct: 366 PDAKMLEELQAETWYQGEMSRKEAEGLLE--KDGDFLVRKSTTNPGSFVLTGMHNGQAKH 423
Query: 493 IKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSLATCNSSLDIKL 624
+ + EG ++ F S+ L+ ++ E SL ++ ++ L
Sbjct: 424 LLLVDPEGTIRTKDRV-FDSISHLINHHLESSLPIVSAGSELCL 466
>D84361-1|BAA12322.1| 594|Homo sapiens p64 isoform of N-Shc
protein.
Length = 594
Score = 44.8 bits (101), Expect = 4e-04
Identities = 29/104 (27%), Positives = 49/104 (47%)
Frame = +1
Query: 313 PQQSPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKL 492
P L+A WY G+++R EA L +DG FLVR ++ + LT G K
Sbjct: 486 PDAKMLEELQAETWYQGEMSRKEAEGLLE--KDGDFLVRKSTTNPGSFVLTGMHNGQAKH 543
Query: 493 IKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSLATCNSSLDIKL 624
+ + EG ++ F S+ L+ ++ E SL ++ ++ L
Sbjct: 544 LLLVDPEGTIRTKDRV-FDSISHLINHHLESSLPIVSAGSELCL 586
>BC032496-1|AAH32496.1| 482|Homo sapiens FYN oncogene related to
SRC, FGR, YES protein.
Length = 482
Score = 44.8 bits (101), Expect = 4e-04
Identities = 30/94 (31%), Positives = 48/94 (51%), Gaps = 8/94 (8%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRD--GTFLVRNASNKDSGYTLTVR-----KGG 480
+P S++A EWY+G + R +A +L + GTFL+R + Y+L++R KG
Sbjct: 139 APVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGD 198
Query: 481 ANKLIKIYH-HEGRYGFREPFEFKSVVDLVCYYS 579
K KI G Y +F+++ LV +YS
Sbjct: 199 HVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYS 232
>BC026314-1|AAH26314.1| 594|Homo sapiens SHC (Src homology 2 domain
containing) transforming protein 3 protein.
Length = 594
Score = 44.8 bits (101), Expect = 4e-04
Identities = 29/104 (27%), Positives = 49/104 (47%)
Frame = +1
Query: 313 PQQSPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKL 492
P L+A WY G+++R EA L +DG FLVR ++ + LT G K
Sbjct: 486 PDAKMLEELQAETWYQGEMSRKEAEGLLE--KDGDFLVRKSTTNPGSFVLTGMHNGQAKH 543
Query: 493 IKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSLATCNSSLDIKL 624
+ + EG ++ F S+ L+ ++ E SL ++ ++ L
Sbjct: 544 LLLVDPEGTIQTKDRV-FDSISHLINHHLESSLPIVSAGSELCL 586
>AL583849-1|CAH73120.1| 509|Homo sapiens Src homology 2 domain
containing adaptor protein B protein.
Length = 509
Score = 44.8 bits (101), Expect = 4e-04
Identities = 28/91 (30%), Positives = 46/91 (50%), Gaps = 2/91 (2%)
Frame = +1
Query: 325 PEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIY 504
P LE WY G I+R +A LR ++ ++LVRN+ Y+L++R +K+
Sbjct: 401 PAVPLEKQIWYHGAISRGDAENLLRLCKECSYLVRNSQTSKHDYSLSLRSNQGFMHMKLA 460
Query: 505 HHEGRY--GFREPFEFKSVVDLVCYYSEYSL 591
+ +Y G P F SV +++ YY+ L
Sbjct: 461 KTKEKYVLGQNSP-PFDSVPEVIHYYTTRKL 490
>AL353150-2|CAI16865.1| 594|Homo sapiens SHC (Src homology 2 domain
containing) transforming protein 3 protein.
Length = 594
Score = 44.8 bits (101), Expect = 4e-04
Identities = 29/104 (27%), Positives = 49/104 (47%)
Frame = +1
Query: 313 PQQSPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKL 492
P L+A WY G+++R EA L +DG FLVR ++ + LT G K
Sbjct: 486 PDAKMLEELQAETWYQGEMSRKEAEGLLE--KDGDFLVRKSTTNPGSFVLTGMHNGQAKH 543
Query: 493 IKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSLATCNSSLDIKL 624
+ + EG ++ F S+ L+ ++ E SL ++ ++ L
Sbjct: 544 LLLVDPEGTIRTKDRV-FDSISHLINHHLESSLPIVSAGSELCL 586
>AL161448-1|CAH73192.1| 509|Homo sapiens Src homology 2 domain
containing adaptor protein B protein.
Length = 509
Score = 44.8 bits (101), Expect = 4e-04
Identities = 28/91 (30%), Positives = 46/91 (50%), Gaps = 2/91 (2%)
Frame = +1
Query: 325 PEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIY 504
P LE WY G I+R +A LR ++ ++LVRN+ Y+L++R +K+
Sbjct: 401 PAVPLEKQIWYHGAISRGDAENLLRLCKECSYLVRNSQTSKHDYSLSLRSNQGFMHMKLA 460
Query: 505 HHEGRY--GFREPFEFKSVVDLVCYYSEYSL 591
+ +Y G P F SV +++ YY+ L
Sbjct: 461 KTKEKYVLGQNSP-PFDSVPEVIHYYTTRKL 490
>AL160054-4|CAI41366.1| 594|Homo sapiens SHC (Src homology 2 domain
containing) transforming protein 3 protein.
Length = 594
Score = 44.8 bits (101), Expect = 4e-04
Identities = 29/104 (27%), Positives = 49/104 (47%)
Frame = +1
Query: 313 PQQSPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKL 492
P L+A WY G+++R EA L +DG FLVR ++ + LT G K
Sbjct: 486 PDAKMLEELQAETWYQGEMSRKEAEGLLE--KDGDFLVRKSTTNPGSFVLTGMHNGQAKH 543
Query: 493 IKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSLATCNSSLDIKL 624
+ + EG ++ F S+ L+ ++ E SL ++ ++ L
Sbjct: 544 LLLVDPEGTIRTKDRV-FDSISHLINHHLESSLPIVSAGSELCL 586
>AL138752-4|CAI13876.1| 509|Homo sapiens Src homology 2 domain
containing adaptor protein B protein.
Length = 509
Score = 44.8 bits (101), Expect = 4e-04
Identities = 28/91 (30%), Positives = 46/91 (50%), Gaps = 2/91 (2%)
Frame = +1
Query: 325 PEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIY 504
P LE WY G I+R +A LR ++ ++LVRN+ Y+L++R +K+
Sbjct: 401 PAVPLEKQIWYHGAISRGDAENLLRLCKECSYLVRNSQTSKHDYSLSLRSNQGFMHMKLA 460
Query: 505 HHEGRY--GFREPFEFKSVVDLVCYYSEYSL 591
+ +Y G P F SV +++ YY+ L
Sbjct: 461 KTKEKYVLGQNSP-PFDSVPEVIHYYTTRKL 490
>U22322-1|AAC50116.1| 505|Homo sapiens Rak protein.
Length = 505
Score = 44.4 bits (100), Expect = 6e-04
Identities = 25/94 (26%), Positives = 50/94 (53%), Gaps = 3/94 (3%)
Frame = +1
Query: 328 EHSLEAAEWYWGDITRDEANEKL--RDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
+ SL+A W++G I R +A ++L + + G+FL+R + ++ ++L+V G K +I
Sbjct: 108 DRSLQAEAWFFGAIRRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGAVVKHYRI 167
Query: 502 YH-HEGRYGFREPFEFKSVVDLVCYYSEYSLATC 600
EG + F ++ + V +Y++ S C
Sbjct: 168 KRLDEGGFFLTRRRIFSTLNEFVSHYTKTSDGLC 201
>M15990-1|AAA35735.1| 543|Homo sapiens protein ( Human c-yes-1
mRNA. ).
Length = 543
Score = 44.4 bits (100), Expect = 6e-04
Identities = 30/102 (29%), Positives = 51/102 (50%), Gaps = 8/102 (7%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRD--TRDGTFLVRNASNKDSGYTLTVR-----KGG 480
+P S++A EWY+G + R +A L + + G FLVR + Y+L++R +G
Sbjct: 148 APADSIQAEEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDWDEIRGD 207
Query: 481 ANKLIKIYH-HEGRYGFREPFEFKSVVDLVCYYSEYSLATCN 603
K KI G Y +F ++ LV +Y+E++ C+
Sbjct: 208 NVKHYKIRKLDNGGYYITTRAQFDTLQKLVKHYTEHADGLCH 249
>BC048960-1|AAH48960.1| 543|Homo sapiens v-yes-1 Yamaguchi sarcoma
viral oncogene homolog 1 protein.
Length = 543
Score = 44.4 bits (100), Expect = 6e-04
Identities = 30/102 (29%), Positives = 51/102 (50%), Gaps = 8/102 (7%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRD--TRDGTFLVRNASNKDSGYTLTVR-----KGG 480
+P S++A EWY+G + R +A L + + G FLVR + Y+L++R +G
Sbjct: 148 APADSIQAEEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDWDEIRGD 207
Query: 481 ANKLIKIYH-HEGRYGFREPFEFKSVVDLVCYYSEYSLATCN 603
K KI G Y +F ++ LV +Y+E++ C+
Sbjct: 208 NVKHYKIRKLDNGGYYITTRAQFDTLQKLVKHYTEHADGLCH 249
>X75342-1|CAA53091.1| 596|Homo sapiens Shb protein.
Length = 596
Score = 44.0 bits (99), Expect = 7e-04
Identities = 28/91 (30%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
Frame = +1
Query: 325 PEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIY 504
P LE WY G I+R +A LR ++ ++LVRN+ Y L++R +K+
Sbjct: 488 PAVPLEKQIWYHGAISRGDAENLLRLCKECSYLVRNSQTSKHDYPLSLRSNQGFMHMKLA 547
Query: 505 HHEGRY--GFREPFEFKSVVDLVCYYSEYSL 591
+ +Y G P F SV +++ YY+ L
Sbjct: 548 KTKEKYVLGQNSP-PFDSVPEVIHYYTTRKL 577
>X17576-1|CAA35599.1| 377|Homo sapiens protein ( Human melanoma
mRNA for nck protein, showing homology to src. ).
Length = 377
Score = 44.0 bits (99), Expect = 7e-04
Identities = 22/83 (26%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
Frame = +1
Query: 352 WYWGDITRDEANEKLRDT-RDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGF 528
WY+G +TR +A L + +G FL+R++ + + ++++++ G NK K+ E Y
Sbjct: 282 WYYGKVTRHQAEMALNERGHEGDFLIRDSESSPNDFSVSLKAQGKNKHFKVQLKETVYCI 341
Query: 529 REPFEFKSVVDLVCYYSEYSLAT 597
+ +F ++ +LV +Y + + T
Sbjct: 342 GQR-KFSTMEELVEHYKKAPIFT 363
>U34379-1|AAB60412.1| 527|Homo sapiens tyrosine kinase protein.
Length = 527
Score = 44.0 bits (99), Expect = 7e-04
Identities = 29/89 (32%), Positives = 51/89 (57%), Gaps = 8/89 (8%)
Frame = +1
Query: 334 SLEAAEWYWGDITRDEANEKLR-DTRDGTFLVRNASNKDSGYTLTVRKG---GANKLIKI 501
+LE EWY +ITR++A LR ++++G F+VR++ + S YT++V G IK
Sbjct: 144 NLEIYEWYHRNITRNQAEHLLRQESKEGAFIVRDSRHLGS-YTISVFMGARRSTEAAIKH 202
Query: 502 Y----HHEGRYGFREPFEFKSVVDLVCYY 576
Y + G++ E F+S+ +L+ Y+
Sbjct: 203 YQIKKNDSGQWYVAERHAFQSIPELIWYH 231
>U00803-1|AAA18284.1| 505|Homo sapiens SRC-like tyrosine kinase
protein.
Length = 505
Score = 44.0 bits (99), Expect = 7e-04
Identities = 25/94 (26%), Positives = 50/94 (53%), Gaps = 3/94 (3%)
Frame = +1
Query: 328 EHSLEAAEWYWGDITRDEANEKL--RDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
+ SL+A W++G I R +A ++L + + G+FL+R + ++ ++L+V G K +I
Sbjct: 108 DRSLQAEPWFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGAVVKHYRI 167
Query: 502 YH-HEGRYGFREPFEFKSVVDLVCYYSEYSLATC 600
EG + F ++ + V +Y++ S C
Sbjct: 168 KRLDEGGFFLTRRRIFSTLNEFVSHYTKTSDGLC 201
>L27071-1|AAA74557.1| 527|Homo sapiens tyrosine kinase protein.
Length = 527
Score = 44.0 bits (99), Expect = 7e-04
Identities = 29/89 (32%), Positives = 51/89 (57%), Gaps = 8/89 (8%)
Frame = +1
Query: 334 SLEAAEWYWGDITRDEANEKLR-DTRDGTFLVRNASNKDSGYTLTVRKG---GANKLIKI 501
+LE EWY +ITR++A LR ++++G F+VR++ + S YT++V G IK
Sbjct: 144 NLEIYEWYHRNITRNQAEHLLRQESKEGAFIVRDSRHLGS-YTISVFMGARRSTEAAIKH 202
Query: 502 Y----HHEGRYGFREPFEFKSVVDLVCYY 576
Y + G++ E F+S+ +L+ Y+
Sbjct: 203 YQIKKNDSGQWYVAERHAFQSIPELIWYH 231
>BC012916-1|AAH12916.1| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 44.0 bits (99), Expect = 7e-04
Identities = 25/94 (26%), Positives = 50/94 (53%), Gaps = 3/94 (3%)
Frame = +1
Query: 328 EHSLEAAEWYWGDITRDEANEKL--RDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
+ SL+A W++G I R +A ++L + + G+FL+R + ++ ++L+V G K +I
Sbjct: 108 DRSLQAEPWFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGAVVKHYRI 167
Query: 502 YH-HEGRYGFREPFEFKSVVDLVCYYSEYSLATC 600
EG + F ++ + V +Y++ S C
Sbjct: 168 KRLDEGGFFLTRRRIFSTLNEFVSHYTKTSDGLC 201
>BC006403-1|AAH06403.1| 377|Homo sapiens NCK adaptor protein 1
protein.
Length = 377
Score = 44.0 bits (99), Expect = 7e-04
Identities = 22/83 (26%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
Frame = +1
Query: 352 WYWGDITRDEANEKLRDT-RDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGF 528
WY+G +TR +A L + +G FL+R++ + + ++++++ G NK K+ E Y
Sbjct: 282 WYYGKVTRHQAEMALNERGHEGDFLIRDSESSPNDFSVSLKAQGKNKHFKVQLKETVYCI 341
Query: 529 REPFEFKSVVDLVCYYSEYSLAT 597
+ +F ++ +LV +Y + + T
Sbjct: 342 GQR-KFSTMEELVEHYKKAPIFT 363
>AL357141-2|CAI16469.1| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 44.0 bits (99), Expect = 7e-04
Identities = 25/94 (26%), Positives = 50/94 (53%), Gaps = 3/94 (3%)
Frame = +1
Query: 328 EHSLEAAEWYWGDITRDEANEKL--RDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
+ SL+A W++G I R +A ++L + + G+FL+R + ++ ++L+V G K +I
Sbjct: 108 DRSLQAEPWFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGAVVKHYRI 167
Query: 502 YH-HEGRYGFREPFEFKSVVDLVCYYSEYSLATC 600
EG + F ++ + V +Y++ S C
Sbjct: 168 KRLDEGGFFLTRRRIFSTLNEFVSHYTKTSDGLC 201
>AL121963-8|CAB87592.2| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 44.0 bits (99), Expect = 7e-04
Identities = 25/94 (26%), Positives = 50/94 (53%), Gaps = 3/94 (3%)
Frame = +1
Query: 328 EHSLEAAEWYWGDITRDEANEKL--RDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
+ SL+A W++G I R +A ++L + + G+FL+R + ++ ++L+V G K +I
Sbjct: 108 DRSLQAEPWFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGAVVKHYRI 167
Query: 502 YH-HEGRYGFREPFEFKSVVDLVCYYSEYSLATC 600
EG + F ++ + V +Y++ S C
Sbjct: 168 KRLDEGGFFLTRRRIFSTLNEFVSHYTKTSDGLC 201
>U44403-1|AAC27662.1| 276|Homo sapiens Src-like adapter protein
protein.
Length = 276
Score = 43.6 bits (98), Expect = 0.001
Identities = 27/86 (31%), Positives = 46/86 (53%), Gaps = 3/86 (3%)
Frame = +1
Query: 352 WYWGDITRDEANEKLR--DTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYG 525
W + + RD+A E L+ DT+ G+F++R + K Y+L+VR K +I+ +
Sbjct: 84 WLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRHRQV-KHYRIFRLPNNWY 142
Query: 526 FREP-FEFKSVVDLVCYYSEYSLATC 600
+ P F+ + DLV +YSE + C
Sbjct: 143 YISPRLTFQCLEDLVNHYSEVADGLC 168
>U30473-1|AAC50357.1| 276|Homo sapiens src-like adapter protein
protein.
Length = 276
Score = 43.6 bits (98), Expect = 0.001
Identities = 27/86 (31%), Positives = 46/86 (53%), Gaps = 3/86 (3%)
Frame = +1
Query: 352 WYWGDITRDEANEKLR--DTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYG 525
W + + RD+A E L+ DT+ G+F++R + K Y+L+VR K +I+ +
Sbjct: 84 WLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRHRQV-KHYRIFRLPNNWY 142
Query: 526 FREP-FEFKSVVDLVCYYSEYSLATC 600
+ P F+ + DLV +YSE + C
Sbjct: 143 YISPRLTFQCLEDLVNHYSEVADGLC 168
>D89077-1|BAA13758.1| 276|Homo sapiens Src-like adapter protein
protein.
Length = 276
Score = 43.6 bits (98), Expect = 0.001
Identities = 27/86 (31%), Positives = 46/86 (53%), Gaps = 3/86 (3%)
Frame = +1
Query: 352 WYWGDITRDEANEKLR--DTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYG 525
W + + RD+A E L+ DT+ G+F++R + K Y+L+VR K +I+ +
Sbjct: 84 WLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRHRQV-KHYRIFRLPNNWY 142
Query: 526 FREP-FEFKSVVDLVCYYSEYSLATC 600
+ P F+ + DLV +YSE + C
Sbjct: 143 YISPRLTFQCLEDLVNHYSEVADGLC 168
>CR536537-1|CAG38774.1| 276|Homo sapiens SLA protein.
Length = 276
Score = 43.6 bits (98), Expect = 0.001
Identities = 27/86 (31%), Positives = 46/86 (53%), Gaps = 3/86 (3%)
Frame = +1
Query: 352 WYWGDITRDEANEKLR--DTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYG 525
W + + RD+A E L+ DT+ G+F++R + K Y+L+VR K +I+ +
Sbjct: 84 WLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRHRQV-KHYRIFRLPNNWY 142
Query: 526 FREP-FEFKSVVDLVCYYSEYSLATC 600
+ P F+ + DLV +YSE + C
Sbjct: 143 YISPRLTFQCLEDLVNHYSEVADGLC 168
>BC007586-1|AAH07586.1| 233|Homo sapiens SHF protein protein.
Length = 233
Score = 43.6 bits (98), Expect = 0.001
Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 3/92 (3%)
Frame = +1
Query: 325 PEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGA---NKLI 495
P LE WY G I+R +A LR ++ ++LVRN+ + ++L+++ KL
Sbjct: 124 PALPLENQVWYHGAISRTDAENLLRLCKEASYLVRNSETSKNDFSLSLKSSQGFMHMKLS 183
Query: 496 KIYHHEGRYGFREPFEFKSVVDLVCYYSEYSL 591
+ H+ G P F SV ++V +Y+ L
Sbjct: 184 RTKEHKYVLGQNSP-PFSSVPEIVHHYASRKL 214
>BC007042-1|AAH07042.1| 276|Homo sapiens Src-like-adaptor protein.
Length = 276
Score = 43.6 bits (98), Expect = 0.001
Identities = 27/86 (31%), Positives = 46/86 (53%), Gaps = 3/86 (3%)
Frame = +1
Query: 352 WYWGDITRDEANEKLR--DTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYG 525
W + + RD+A E L+ DT+ G+F++R + K Y+L+VR K +I+ +
Sbjct: 84 WLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRHRQV-KHYRIFRLPNNWY 142
Query: 526 FREP-FEFKSVVDLVCYYSEYSLATC 600
+ P F+ + DLV +YSE + C
Sbjct: 143 YISPRLTFQCLEDLVNHYSEVADGLC 168
>AB110420-1|BAC76765.1| 428|Homo sapiens MIST protein.
Length = 428
Score = 43.2 bits (97), Expect = 0.001
Identities = 28/102 (27%), Positives = 51/102 (50%), Gaps = 9/102 (8%)
Frame = +1
Query: 313 PQQSPEHSLEAAEWYWGDITRDEANEK-LRDTRDGTFLVRNAS--NKDSGYTLTV--RKG 477
P++S ++ EWY G+ +R E +++ +DG+FLVR+ S +K+ Y L V
Sbjct: 296 PKRSDRKDVQHNEWYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVFYENK 355
Query: 478 GANKLIKIYHHEGRY----GFREPFEFKSVVDLVCYYSEYSL 591
N I+ ++ G R +F SV D++ +Y + +
Sbjct: 356 VYNVKIRFLERNQQFALGTGLRGDEKFDSVEDIIEHYKNFPI 397
>U20158-1|AAC50135.1| 533|Homo sapiens SLP-76 protein.
Length = 533
Score = 42.7 bits (96), Expect = 0.002
Identities = 36/102 (35%), Positives = 49/102 (48%), Gaps = 9/102 (8%)
Frame = +1
Query: 313 PQQSPEHSLEAAEWYWGDITRDEANEKLRD-TRDGTFLVRNASNK--DSGYTLTVRKGGA 483
P + E + EWY ITR EA LR +DGTFLVR++S K + Y L V
Sbjct: 409 PSPAEEENSLNEEWYVSYITRPEAEAALRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDK 468
Query: 484 NKLIKI-YHHEGRY-----GFREPFEFKSVVDLVCYYSEYSL 591
I+I Y E + G R +F SV D++ Y+ + L
Sbjct: 469 VYNIQIRYQKESQVYLLGTGLRGKEDFLSVSDIIDYFRKMPL 510
>BT007273-1|AAP35937.1| 533|Homo sapiens lymphocyte cytosolic
protein 2 (SH2 domain containing leukocyte protein of
76kD protein.
Length = 533
Score = 42.7 bits (96), Expect = 0.002
Identities = 36/102 (35%), Positives = 49/102 (48%), Gaps = 9/102 (8%)
Frame = +1
Query: 313 PQQSPEHSLEAAEWYWGDITRDEANEKLRD-TRDGTFLVRNASNK--DSGYTLTVRKGGA 483
P + E + EWY ITR EA LR +DGTFLVR++S K + Y L V
Sbjct: 409 PSPAEEENSLNEEWYVSYITRPEAEAALRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDK 468
Query: 484 NKLIKI-YHHEGRY-----GFREPFEFKSVVDLVCYYSEYSL 591
I+I Y E + G R +F SV D++ Y+ + L
Sbjct: 469 VYNIQIRYQKESQVYLLGTGLRGKEDFLSVSDIIDYFRKMPL 510
>BC016618-1|AAH16618.1| 533|Homo sapiens lymphocyte cytosolic
protein 2 (SH2 domain containing leukocyte protein of
76kD protein.
Length = 533
Score = 42.7 bits (96), Expect = 0.002
Identities = 36/102 (35%), Positives = 49/102 (48%), Gaps = 9/102 (8%)
Frame = +1
Query: 313 PQQSPEHSLEAAEWYWGDITRDEANEKLRD-TRDGTFLVRNASNK--DSGYTLTVRKGGA 483
P + E + EWY ITR EA LR +DGTFLVR++S K + Y L V
Sbjct: 409 PSPAEEENSLNEEWYVSYITRPEAEAALRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDK 468
Query: 484 NKLIKI-YHHEGRY-----GFREPFEFKSVVDLVCYYSEYSL 591
I+I Y E + G R +F SV D++ Y+ + L
Sbjct: 469 VYNIQIRYQKESQVYLLGTGLRGKEDFLSVSDIIDYFRKMPL 510
>Z97989-6|CAI22299.1| 485|Homo sapiens FYN oncogene related to SRC,
FGR, YES protein.
Length = 485
Score = 42.3 bits (95), Expect = 0.002
Identities = 29/99 (29%), Positives = 47/99 (47%), Gaps = 8/99 (8%)
Frame = +1
Query: 328 EHSLEAAEWYWGDITRDEANEKLRDTRD--GTFLVRNASNKDSGYTLTVR-----KGGAN 486
++ EWY+G + R +A +L + GTFL+R + Y+L++R KG
Sbjct: 92 DYEARTEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHV 151
Query: 487 KLIKIYH-HEGRYGFREPFEFKSVVDLVCYYSEYSLATC 600
K KI G Y +F+++ LV +YSE + C
Sbjct: 152 KHYKIRKLDNGGYYITTRAQFETLQQLVQHYSEKADGLC 190
>S65186-1|AAB28072.2| 620|Homo sapiens EMT protein.
Length = 620
Score = 42.3 bits (95), Expect = 0.002
Identities = 34/98 (34%), Positives = 52/98 (53%), Gaps = 11/98 (11%)
Frame = +1
Query: 316 QQSPEHSLEAAEWYWGDITRDEANEKLRDT-RDGTFLVRNASNKDSGYTLTVRKGGA--- 483
++SP ++LE EWY I+RD+A + L DT ++G F+VR+ S YT++V
Sbjct: 228 EKSP-NNLETYEWYNKSISRDKAEKLLLDTGKEGAFMVRD-SRTAGTYTVSVFTKAVVSE 285
Query: 484 -NKLIKIYH------HEGRYGFREPFEFKSVVDLVCYY 576
N IK YH + RY E + F S+ L+ Y+
Sbjct: 286 NNPCIKHYHIKETNDNPKRYYVAEKYVFDSIPLLINYH 323
>L10717-1|AAA36748.1| 620|Homo sapiens tyrosine kinase protein.
Length = 620
Score = 42.3 bits (95), Expect = 0.002
Identities = 34/98 (34%), Positives = 52/98 (53%), Gaps = 11/98 (11%)
Frame = +1
Query: 316 QQSPEHSLEAAEWYWGDITRDEANEKLRDT-RDGTFLVRNASNKDSGYTLTVRKGGA--- 483
++SP ++LE EWY I+RD+A + L DT ++G F+VR+ S YT++V
Sbjct: 228 EKSP-NNLETYEWYNKSISRDKAEKLLLDTGKEGAFMVRD-SRTAGTYTVSVFTKAVVSE 285
Query: 484 -NKLIKIYH------HEGRYGFREPFEFKSVVDLVCYY 576
N IK YH + RY E + F S+ L+ Y+
Sbjct: 286 NNPCIKHYHIKETNDNPKRYYVAEKYVFDSIPLLINYH 323
>D13720-1|BAA02873.1| 620|Homo sapiens ITK protein.
Length = 620
Score = 42.3 bits (95), Expect = 0.002
Identities = 34/98 (34%), Positives = 52/98 (53%), Gaps = 11/98 (11%)
Frame = +1
Query: 316 QQSPEHSLEAAEWYWGDITRDEANEKLRDT-RDGTFLVRNASNKDSGYTLTVRKGGA--- 483
++SP ++LE EWY I+RD+A + L DT ++G F+VR+ S YT++V
Sbjct: 228 EKSP-NNLETYEWYNKSISRDKAEKLLLDTGKEGAFMVRD-SRTAGTYTVSVFTKAVVSE 285
Query: 484 -NKLIKIYH------HEGRYGFREPFEFKSVVDLVCYY 576
N IK YH + RY E + F S+ L+ Y+
Sbjct: 286 NNPCIKHYHIKETNDNPKRYYVAEKYVFDSIPLLINYH 323
>BT019994-1|AAV38797.1| 276|Homo sapiens Src-like-adaptor protein.
Length = 276
Score = 42.3 bits (95), Expect = 0.002
Identities = 26/86 (30%), Positives = 46/86 (53%), Gaps = 3/86 (3%)
Frame = +1
Query: 352 WYWGDITRDEANEKLR--DTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYG 525
W + + RD+A E L+ DT+ G+F++R + K Y+L+VR K +I+ +
Sbjct: 84 WLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYSLSVRHRQV-KHYRIFRLPNNWY 142
Query: 526 FREP-FEFKSVVDLVCYYSEYSLATC 600
+ P F+ + DL+ +YSE + C
Sbjct: 143 YISPRLTFQCLEDLMNHYSEVADGLC 168
>BC109078-1|AAI09079.1| 620|Homo sapiens IL2-inducible T-cell
kinase protein.
Length = 620
Score = 42.3 bits (95), Expect = 0.002
Identities = 34/98 (34%), Positives = 52/98 (53%), Gaps = 11/98 (11%)
Frame = +1
Query: 316 QQSPEHSLEAAEWYWGDITRDEANEKLRDT-RDGTFLVRNASNKDSGYTLTVRKGGA--- 483
++SP ++LE EWY I+RD+A + L DT ++G F+VR+ S YT++V
Sbjct: 228 EKSP-NNLETYEWYNKSISRDKAEKLLLDTGKEGAFMVRD-SRTAGTYTVSVFTKAVVSE 285
Query: 484 -NKLIKIYH------HEGRYGFREPFEFKSVVDLVCYY 576
N IK YH + RY E + F S+ L+ Y+
Sbjct: 286 NNPCIKHYHIKETNDNPKRYYVAEKYVFDSIPLLINYH 323
>BC109077-1|AAI09078.1| 620|Homo sapiens IL2-inducible T-cell
kinase protein.
Length = 620
Score = 42.3 bits (95), Expect = 0.002
Identities = 34/98 (34%), Positives = 52/98 (53%), Gaps = 11/98 (11%)
Frame = +1
Query: 316 QQSPEHSLEAAEWYWGDITRDEANEKLRDT-RDGTFLVRNASNKDSGYTLTVRKGGA--- 483
++SP ++LE EWY I+RD+A + L DT ++G F+VR+ S YT++V
Sbjct: 228 EKSP-NNLETYEWYNKSISRDKAEKLLLDTGKEGAFMVRD-SRTAGTYTVSVFTKAVVSE 285
Query: 484 -NKLIKIYH------HEGRYGFREPFEFKSVVDLVCYY 576
N IK YH + RY E + F S+ L+ Y+
Sbjct: 286 NNPCIKHYHIKETNDNPKRYYVAEKYVFDSIPLLINYH 323
>BC033907-1|AAH33907.1| 630|Homo sapiens SHC (Src homology 2 domain
containing) family, member 4 protein.
Length = 630
Score = 42.3 bits (95), Expect = 0.002
Identities = 28/99 (28%), Positives = 49/99 (49%)
Frame = +1
Query: 328 EHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYH 507
+ L + E Y G ++R A L +DG FLVR ++ Y L+ +GG K + +
Sbjct: 518 KQQLWSEECYHGKLSRKAAESLL--VKDGDFLVRESATSPGQYVLSGLQGGQAKHLLLVD 575
Query: 508 HEGRYGFREPFEFKSVVDLVCYYSEYSLATCNSSLDIKL 624
EG+ ++ F +V L+ Y+ + SL +S ++ L
Sbjct: 576 PEGKVRTKD-HVFDNVGHLIRYHMDNSLPIISSGSEVSL 613
>AY464565-1|AAR19363.1| 630|Homo sapiens rai-like protein RaLP
protein.
Length = 630
Score = 42.3 bits (95), Expect = 0.002
Identities = 28/99 (28%), Positives = 49/99 (49%)
Frame = +1
Query: 328 EHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYH 507
+ L + E Y G ++R A L +DG FLVR ++ Y L+ +GG K + +
Sbjct: 518 KQQLWSEECYHGKLSRKAAESLL--VKDGDFLVRESATSPGQYVLSGLQGGQAKHLLLVD 575
Query: 508 HEGRYGFREPFEFKSVVDLVCYYSEYSLATCNSSLDIKL 624
EG+ ++ F +V L+ Y+ + SL +S ++ L
Sbjct: 576 PEGKVRTKD-HVFDNVGHLIRYHMDNSLPIISSGSEVSL 613
>AY358250-1|AAQ88617.1| 387|Homo sapiens LPAL6438 protein.
Length = 387
Score = 42.3 bits (95), Expect = 0.002
Identities = 28/99 (28%), Positives = 49/99 (49%)
Frame = +1
Query: 328 EHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYH 507
+ L + E Y G ++R A L +DG FLVR ++ Y L+ +GG K + +
Sbjct: 275 KQQLWSEECYHGKLSRKAAESLL--VKDGDFLVRESATSPGQYVLSGLQGGQAKHLLLVD 332
Query: 508 HEGRYGFREPFEFKSVVDLVCYYSEYSLATCNSSLDIKL 624
EG+ ++ F +V L+ Y+ + SL +S ++ L
Sbjct: 333 PEGKVRTKD-HVFDNVGHLIRYHMDNSLPIISSGSEVSL 370
>AB209622-1|BAD92859.1| 376|Homo sapiens IL2-inducible T-cell
kinase variant protein.
Length = 376
Score = 42.3 bits (95), Expect = 0.002
Identities = 34/98 (34%), Positives = 52/98 (53%), Gaps = 11/98 (11%)
Frame = +1
Query: 316 QQSPEHSLEAAEWYWGDITRDEANEKLRDT-RDGTFLVRNASNKDSGYTLTVRKGGA--- 483
++SP ++LE EWY I+RD+A + L DT ++G F+VR+ S YT++V
Sbjct: 273 EKSP-NNLETYEWYNKSISRDKAEKLLLDTGKEGAFMVRD-SRTAGTYTVSVFTKAVVSE 330
Query: 484 -NKLIKIYH------HEGRYGFREPFEFKSVVDLVCYY 576
N IK YH + RY E + F S+ L+ Y+
Sbjct: 331 NNPCIKHYHIKETNDNPKRYYVAEKYVFDSIPLLINYH 368
>X62852-1|CAA44664.1| 160|Homo sapiens ash protein protein.
Length = 160
Score = 41.9 bits (94), Expect = 0.003
Identities = 26/83 (31%), Positives = 45/83 (54%), Gaps = 2/83 (2%)
Frame = +1
Query: 352 WYWGDITRDEANEKLRDTR-DGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHH-EGRYG 525
W++G I R +A E L R DG FL+R + + ++L+V+ G + K+ G+Y
Sbjct: 3 WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKY- 61
Query: 526 FREPFEFKSVVDLVCYYSEYSLA 594
F +F S+ +LV Y+ S++
Sbjct: 62 FLWVVKFNSLNELVDYHRSTSVS 84
>M96995-1|AAA58448.1| 217|Homo sapiens epidermal growth factor
receptor-binding protein GRB2 protein.
Length = 217
Score = 41.9 bits (94), Expect = 0.003
Identities = 26/83 (31%), Positives = 45/83 (54%), Gaps = 2/83 (2%)
Frame = +1
Query: 352 WYWGDITRDEANEKLRDTR-DGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHH-EGRYG 525
W++G I R +A E L R DG FL+R + + ++L+V+ G + K+ G+Y
Sbjct: 60 WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKY- 118
Query: 526 FREPFEFKSVVDLVCYYSEYSLA 594
F +F S+ +LV Y+ S++
Sbjct: 119 FLWVVKFNSLNELVDYHRSTSVS 141
>CR541942-1|CAG46740.1| 217|Homo sapiens GRB2 protein.
Length = 217
Score = 41.9 bits (94), Expect = 0.003
Identities = 26/83 (31%), Positives = 45/83 (54%), Gaps = 2/83 (2%)
Frame = +1
Query: 352 WYWGDITRDEANEKLRDTR-DGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHH-EGRYG 525
W++G I R +A E L R DG FL+R + + ++L+V+ G + K+ G+Y
Sbjct: 60 WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKY- 118
Query: 526 FREPFEFKSVVDLVCYYSEYSLA 594
F +F S+ +LV Y+ S++
Sbjct: 119 FLWVVKFNSLNELVDYHRSTSVS 141
>CR450363-1|CAG29359.1| 217|Homo sapiens GRB2 protein.
Length = 217
Score = 41.9 bits (94), Expect = 0.003
Identities = 26/83 (31%), Positives = 45/83 (54%), Gaps = 2/83 (2%)
Frame = +1
Query: 352 WYWGDITRDEANEKLRDTR-DGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHH-EGRYG 525
W++G I R +A E L R DG FL+R + + ++L+V+ G + K+ G+Y
Sbjct: 60 WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKY- 118
Query: 526 FREPFEFKSVVDLVCYYSEYSLA 594
F +F S+ +LV Y+ S++
Sbjct: 119 FLWVVKFNSLNELVDYHRSTSVS 141
>BC000631-1|AAH00631.1| 217|Homo sapiens growth factor
receptor-bound protein 2 protein.
Length = 217
Score = 41.9 bits (94), Expect = 0.003
Identities = 26/83 (31%), Positives = 45/83 (54%), Gaps = 2/83 (2%)
Frame = +1
Query: 352 WYWGDITRDEANEKLRDTR-DGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHH-EGRYG 525
W++G I R +A E L R DG FL+R + + ++L+V+ G + K+ G+Y
Sbjct: 60 WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKY- 118
Query: 526 FREPFEFKSVVDLVCYYSEYSLA 594
F +F S+ +LV Y+ S++
Sbjct: 119 FLWVVKFNSLNELVDYHRSTSVS 141
>AF498925-1|AAM21073.1| 217|Homo sapiens growth factor
receptor-bound protein 2 protein.
Length = 217
Score = 41.9 bits (94), Expect = 0.003
Identities = 26/83 (31%), Positives = 45/83 (54%), Gaps = 2/83 (2%)
Frame = +1
Query: 352 WYWGDITRDEANEKLRDTR-DGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHH-EGRYG 525
W++G I R +A E L R DG FL+R + + ++L+V+ G + K+ G+Y
Sbjct: 60 WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKY- 118
Query: 526 FREPFEFKSVVDLVCYYSEYSLA 594
F +F S+ +LV Y+ S++
Sbjct: 119 FLWVVKFNSLNELVDYHRSTSVS 141
>AF063618-1|AAC72075.1| 217|Homo sapiens growth factor
receptor-bound protein 2 protein.
Length = 217
Score = 41.9 bits (94), Expect = 0.003
Identities = 26/83 (31%), Positives = 45/83 (54%), Gaps = 2/83 (2%)
Frame = +1
Query: 352 WYWGDITRDEANEKLRDTR-DGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHH-EGRYG 525
W++G I R +A E L R DG FL+R + + ++L+V+ G + K+ G+Y
Sbjct: 60 WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKY- 118
Query: 526 FREPFEFKSVVDLVCYYSEYSLA 594
F +F S+ +LV Y+ S++
Sbjct: 119 FLWVVKFNSLNELVDYHRSTSVS 141
>AJ012793-1|CAB42642.1| 576|Homo sapiens lymphocyte adaptor protein
(Lnk) protein.
Length = 576
Score = 41.5 bits (93), Expect = 0.004
Identities = 28/111 (25%), Positives = 51/111 (45%), Gaps = 4/111 (3%)
Frame = +1
Query: 319 QSPEHSLEAAEWYWGDITRDEANEKLR---DTRDGTFLVRNASNKDSGYTLTVRKGGANK 489
Q +H L W+ G I+R +A + ++ G FLVR + + Y LT G K
Sbjct: 354 QKTDHFLSCYPWFHGPISRVKAAQLVQLQGPDAHGVFLVRQSETRRGEYVLTFNFQGIAK 413
Query: 490 LIKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSL-ATCNSSLDIKLLXSIV 639
+++ E + F SVVD++ ++ + C ++ D++L +V
Sbjct: 414 HLRLSLTERGQCRVQHLHFPSVVDMLHHFQRSPIPLECGAACDVRLSSYVV 464
>AF055581-1|AAC71695.1| 575|Homo sapiens adaptor protein Lnk
protein.
Length = 575
Score = 41.5 bits (93), Expect = 0.004
Identities = 28/111 (25%), Positives = 51/111 (45%), Gaps = 4/111 (3%)
Frame = +1
Query: 319 QSPEHSLEAAEWYWGDITRDEANEKLR---DTRDGTFLVRNASNKDSGYTLTVRKGGANK 489
Q +H L W+ G I+R +A + ++ G FLVR + + Y LT G K
Sbjct: 353 QKTDHFLSCYPWFHGPISRVKAAQLVQLQGPDAHGVFLVRQSETRRGEYVLTFNFQGIAK 412
Query: 490 LIKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSL-ATCNSSLDIKLLXSIV 639
+++ E + F SVVD++ ++ + C ++ D++L +V
Sbjct: 413 HLRLSLTERGQCRVQHLHFPSVVDMLHHFQRSPIPLECGAACDVRLSSYVV 463
>AB208911-1|BAD92148.1| 439|Homo sapiens lymphocyte adaptor protein
variant protein.
Length = 439
Score = 41.5 bits (93), Expect = 0.004
Identities = 28/111 (25%), Positives = 51/111 (45%), Gaps = 4/111 (3%)
Frame = +1
Query: 319 QSPEHSLEAAEWYWGDITRDEANEKLR---DTRDGTFLVRNASNKDSGYTLTVRKGGANK 489
Q +H L W+ G I+R +A + ++ G FLVR + + Y LT G K
Sbjct: 217 QKTDHFLSCYPWFHGPISRVKAAQLVQLQGPDAHGVFLVRQSETRRGEYVLTFNFQGIAK 276
Query: 490 LIKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSL-ATCNSSLDIKLLXSIV 639
+++ E + F SVVD++ ++ + C ++ D++L +V
Sbjct: 277 HLRLSLTERGQCRVQHLHFPSVVDMLHHFQRSPIPLECGAACDVRLSSYVV 327
>AB032369-1|BAA96241.1| 376|Homo sapiens MIST protein.
Length = 376
Score = 41.5 bits (93), Expect = 0.004
Identities = 28/97 (28%), Positives = 49/97 (50%), Gaps = 9/97 (9%)
Frame = +1
Query: 313 PQQSPEHSLEAAEWYWGDITRDEANEK-LRDTRDGTFLVRNAS--NKDSGYTLTV--RKG 477
P++S ++ EWY G+ +R E +++ +DG+FLVR+ S +K+ Y L V
Sbjct: 278 PKRSDRKDVQHNEWYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVFYENK 337
Query: 478 GANKLIKIYHHEGRY----GFREPFEFKSVVDLVCYY 576
N I+ ++ G R +F SV D++ +Y
Sbjct: 338 VYNVKIRFLERNQQFALGTGLRGDEKFDSVEDIIEHY 374
>X59656-1|CAA42199.1| 303|Homo sapiens CRKL protein.
Length = 303
Score = 41.1 bits (92), Expect = 0.005
Identities = 18/45 (40%), Positives = 27/45 (60%)
Frame = +1
Query: 334 SLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTV 468
S + + WY G ++R EA +L+ R G FLVR++S Y L+V
Sbjct: 8 SSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSV 52
>M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein.
Length = 1130
Score = 41.1 bits (92), Expect = 0.005
Identities = 25/92 (27%), Positives = 48/92 (52%), Gaps = 6/92 (6%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
+P +SLE WY G ++R+ A L +G+FLVR + + S ++++R G ++
Sbjct: 117 TPVNSLEKHSWYHGPVSRNAAEYPLSSGINGSFLVRESESSPSQRSISLRYEG-----RV 171
Query: 502 YHH------EGRYGFREPFEFKSVVDLVCYYS 579
YH+ +G+ F ++ +LV ++S
Sbjct: 172 YHYRINTASDGKLYVSSESRFNTLAELVHHHS 203
>CR541694-1|CAG46495.1| 225|Homo sapiens SOCS3 protein.
Length = 225
Score = 41.1 bits (92), Expect = 0.005
Identities = 20/65 (30%), Positives = 36/65 (55%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEG 516
L+ + +YW +T EAN L GTFL+R++S++ +TL+V+ K ++I G
Sbjct: 41 LQESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGG 100
Query: 517 RYGFR 531
+ +
Sbjct: 101 SFSLQ 105
>CR536497-1|CAG38736.1| 225|Homo sapiens SOCS3 protein.
Length = 225
Score = 41.1 bits (92), Expect = 0.005
Identities = 20/65 (30%), Positives = 36/65 (55%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEG 516
L+ + +YW +T EAN L GTFL+R++S++ +TL+V+ K ++I G
Sbjct: 41 LQESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGG 100
Query: 517 RYGFR 531
+ +
Sbjct: 101 SFSLQ 105
>CR456423-1|CAG30309.1| 303|Homo sapiens CRKL protein.
Length = 303
Score = 41.1 bits (92), Expect = 0.005
Identities = 18/45 (40%), Positives = 27/45 (60%)
Frame = +1
Query: 334 SLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTV 468
S + + WY G ++R EA +L+ R G FLVR++S Y L+V
Sbjct: 8 SSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSV 52
>BT019544-1|AAV38351.1| 225|Homo sapiens suppressor of cytokine
signaling 3 protein.
Length = 225
Score = 41.1 bits (92), Expect = 0.005
Identities = 20/65 (30%), Positives = 36/65 (55%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEG 516
L+ + +YW +T EAN L GTFL+R++S++ +TL+V+ K ++I G
Sbjct: 41 LQESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGG 100
Query: 517 RYGFR 531
+ +
Sbjct: 101 SFSLQ 105
>BC060858-1|AAH60858.1| 225|Homo sapiens suppressor of cytokine
signaling 3 protein.
Length = 225
Score = 41.1 bits (92), Expect = 0.005
Identities = 20/65 (30%), Positives = 36/65 (55%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEG 516
L+ + +YW +T EAN L GTFL+R++S++ +TL+V+ K ++I G
Sbjct: 41 LQESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGG 100
Query: 517 RYGFR 531
+ +
Sbjct: 101 SFSLQ 105
>BC043500-1|AAH43500.1| 303|Homo sapiens v-crk sarcoma virus CT10
oncogene homolog (avian)-like protein.
Length = 303
Score = 41.1 bits (92), Expect = 0.005
Identities = 18/45 (40%), Positives = 27/45 (60%)
Frame = +1
Query: 334 SLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTV 468
S + + WY G ++R EA +L+ R G FLVR++S Y L+V
Sbjct: 8 SSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSV 52
>BC012924-1|AAH12924.1| 280|Homo sapiens DAPP1 protein protein.
Length = 280
Score = 41.1 bits (92), Expect = 0.005
Identities = 29/88 (32%), Positives = 47/88 (53%), Gaps = 3/88 (3%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTR-DGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHE 513
L+ WY G++TR A L DG++L+R+++ Y+L+VR A +K +H E
Sbjct: 30 LQDLGWYHGNLTRHAAEALLLSNGCDGSYLLRDSNETTGLYSLSVR---AKDSVKHFHVE 86
Query: 514 -GRYGFREPF-EFKSVVDLVCYYSEYSL 591
Y F+ F EF S+ D V +++ L
Sbjct: 87 YTGYSFKFGFNEFSSLKDFVKHFANQPL 114
>AF186022-1|AAF14578.1| 280|Homo sapiens B lymphocyte adapter
protein BAM32 protein.
Length = 280
Score = 41.1 bits (92), Expect = 0.005
Identities = 29/88 (32%), Positives = 47/88 (53%), Gaps = 3/88 (3%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTR-DGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHE 513
L+ WY G++TR A L DG++L+R+++ Y+L+VR A +K +H E
Sbjct: 30 LQDLGWYHGNLTRHAAEALLLSNGCDGSYLLRDSNETTGLYSLSVR---AKDSVKHFHVE 86
Query: 514 -GRYGFREPF-EFKSVVDLVCYYSEYSL 591
Y F+ F EF S+ D V +++ L
Sbjct: 87 YTGYSFKFGFNEFSSLKDFVKHFANQPL 114
>AF178987-1|AAF44351.1| 280|Homo sapiens protein-tyrosine
phosphatase D protein.
Length = 280
Score = 41.1 bits (92), Expect = 0.005
Identities = 29/88 (32%), Positives = 47/88 (53%), Gaps = 3/88 (3%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTR-DGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHE 513
L+ WY G++TR A L DG++L+R+++ Y+L+VR A +K +H E
Sbjct: 30 LQDLGWYHGNLTRHAAEALLLSNGCDGSYLLRDSNETTGLYSLSVR---AKDSVKHFHVE 86
Query: 514 -GRYGFREPF-EFKSVVDLVCYYSEYSL 591
Y F+ F EF S+ D V +++ L
Sbjct: 87 YTGYSFKFGFNEFSSLKDFVKHFANQPL 114
>AF163254-1|AAD49697.1| 280|Homo sapiens adaptor protein DAPP1
protein.
Length = 280
Score = 41.1 bits (92), Expect = 0.005
Identities = 29/88 (32%), Positives = 47/88 (53%), Gaps = 3/88 (3%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTR-DGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHE 513
L+ WY G++TR A L DG++L+R+++ Y+L+VR A +K +H E
Sbjct: 30 LQDLGWYHGNLTRHAAEALLLSNGCDGSYLLRDSNETTGLYSLSVR---AKDSVKHFHVE 86
Query: 514 -GRYGFREPF-EFKSVVDLVCYYSEYSL 591
Y F+ F EF S+ D V +++ L
Sbjct: 87 YTGYSFKFGFNEFSSLKDFVKHFANQPL 114
>AF159854-1|AAD42231.1| 225|Homo sapiens cytokine signaling
suppressor protein.
Length = 225
Score = 41.1 bits (92), Expect = 0.005
Identities = 20/65 (30%), Positives = 36/65 (55%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEG 516
L+ + +YW +T EAN L GTFL+R++S++ +TL+V+ K ++I G
Sbjct: 41 LQESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGG 100
Query: 517 RYGFR 531
+ +
Sbjct: 101 SFSLQ 105
>AB006967-1|BAA22537.1| 225|Homo sapiens CIS3 protein.
Length = 225
Score = 41.1 bits (92), Expect = 0.005
Identities = 20/65 (30%), Positives = 36/65 (55%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEG 516
L+ + +YW +T EAN L GTFL+R++S++ +TL+V+ K ++I G
Sbjct: 41 LQESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGG 100
Query: 517 RYGFR 531
+ +
Sbjct: 101 SFSLQ 105
>X83107-1|CAA58169.1| 675|Homo sapiens bmx protein.
Length = 675
Score = 40.3 bits (90), Expect = 0.009
Identities = 28/95 (29%), Positives = 50/95 (52%), Gaps = 8/95 (8%)
Frame = +1
Query: 328 EHSLEAAEWYWGDITRDEANEKLRDT-RDGTFLVRNASNKDSGYTLTVRKGGANK---LI 495
E +L+ +W+ G+I+R ++ + LR ++G F+VRN+S YT+++ N +
Sbjct: 288 EENLDDYDWFAGNISRSQSEQLLRQKGKEGAFMVRNSSQVGM-YTVSLFSKAVNDKKGTV 346
Query: 496 KIYH-H---EGRYGFREPFEFKSVVDLVCYYSEYS 588
K YH H E + E + F S+ L+ Y+ S
Sbjct: 347 KHYHVHTNAENKLYLAENYCFDSIPKLIHYHQHNS 381
>BC016652-1|AAH16652.1| 675|Homo sapiens BMX non-receptor tyrosine
kinase protein.
Length = 675
Score = 40.3 bits (90), Expect = 0.009
Identities = 28/95 (29%), Positives = 50/95 (52%), Gaps = 8/95 (8%)
Frame = +1
Query: 328 EHSLEAAEWYWGDITRDEANEKLRDT-RDGTFLVRNASNKDSGYTLTVRKGGANK---LI 495
E +L+ +W+ G+I+R ++ + LR ++G F+VRN+S YT+++ N +
Sbjct: 288 EENLDDYDWFAGNISRSQSEQLLRQKGKEGAFMVRNSSQVGM-YTVSLFSKAVNDKKGTV 346
Query: 496 KIYH-H---EGRYGFREPFEFKSVVDLVCYYSEYS 588
K YH H E + E + F S+ L+ Y+ S
Sbjct: 347 KHYHVHTNAENKLYLAENYCFDSIPKLIHYHQHNS 381
>AL731544-3|CAI14998.1| 431|Homo sapiens novel SH2
domain-containing protein protein.
Length = 431
Score = 40.3 bits (90), Expect = 0.009
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 2/91 (2%)
Frame = +1
Query: 346 AEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYG 525
A W+ G I+R++A L + +G FLVR S K GYTL+ R K + Y
Sbjct: 323 APWFHGIISREDAEALLENMTEGAFLVR-VSEKIWGYTLSYRLQKGFKHFLVDASGDFYS 381
Query: 526 FR--EPFEFKSVVDLVCYYSEYSLATCNSSL 612
F +P ++ DLV ++ E + L
Sbjct: 382 FLGVDPNRHATLTDLVDFHKEEIITVSGGEL 412
>AF045459-1|AAC08966.1| 697|Homo sapiens Etk/Bmx cytosolic tyrosine
kinase protein.
Length = 697
Score = 40.3 bits (90), Expect = 0.009
Identities = 28/95 (29%), Positives = 50/95 (52%), Gaps = 8/95 (8%)
Frame = +1
Query: 328 EHSLEAAEWYWGDITRDEANEKLRDT-RDGTFLVRNASNKDSGYTLTVRKGGANK---LI 495
E +L+ +W+ G+I+R ++ + LR ++G F+VRN+S YT+++ N +
Sbjct: 311 EENLDDYDWFAGNISRSQSEQLLRQKGKEGAFMVRNSSQVGM-YTVSLFSKAVNDKKGTV 369
Query: 496 KIYH-H---EGRYGFREPFEFKSVVDLVCYYSEYS 588
K YH H E + E + F S+ L+ Y+ S
Sbjct: 370 KHYHVHTNAENKLYLAENYCFDSIPKLIHYHQHNS 404
>AM491363-1|CAM33013.1| 498|Homo sapiens bcr-abl1 e19a2 chimeric
protein protein.
Length = 498
Score = 39.9 bits (89), Expect = 0.012
Identities = 24/92 (26%), Positives = 47/92 (51%), Gaps = 6/92 (6%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
+P +SLE WY G ++R+ A L +G+FLVR + + ++++R G ++
Sbjct: 369 TPVNSLEKHSWYHGPVSRNAAEHLLSSGINGSFLVRESESSPGQRSISLRYEG-----RV 423
Query: 502 YHH------EGRYGFREPFEFKSVVDLVCYYS 579
YH+ +G+ F ++ +LV ++S
Sbjct: 424 YHYRINTASDGKLYVSSESRFNTLAELVHHHS 455
>AL353150-1|CAI16864.1| 105|Homo sapiens SHC (Src homology 2 domain
containing) transforming protein 3 protein.
Length = 105
Score = 39.9 bits (89), Expect = 0.012
Identities = 22/68 (32%), Positives = 32/68 (47%)
Frame = +1
Query: 313 PQQSPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKL 492
P L+A WY G+++R EA L +DG FLVR ++ + LT G K
Sbjct: 34 PDAKMLEELQAETWYQGEMSRKEAEGLLE--KDGDFLVRKSTTNPGSFVLTGMHNGQAKH 91
Query: 493 IKIYHHEG 516
+ + EG
Sbjct: 92 LLLVDPEG 99
>AM491359-1|CAM33009.1| 235|Homo sapiens bcr-abl1 e13a3 chimeric
protein protein.
Length = 235
Score = 39.5 bits (88), Expect = 0.016
Identities = 24/92 (26%), Positives = 47/92 (51%), Gaps = 6/92 (6%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
+P +SLE WY G ++R+ A L +G+FLVR + + ++++R G ++
Sbjct: 106 TPANSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEG-----RV 160
Query: 502 YHH------EGRYGFREPFEFKSVVDLVCYYS 579
YH+ +G+ F ++ +LV ++S
Sbjct: 161 YHYRINTASDGKLYVSSESRFNTLAELVHHHS 192
>X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRNA
encoding p150 protein. ).
Length = 1130
Score = 39.1 bits (87), Expect = 0.021
Identities = 24/92 (26%), Positives = 47/92 (51%), Gaps = 6/92 (6%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
+P +SLE WY G ++R+ A L +G+FLVR + + ++++R G ++
Sbjct: 117 TPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEG-----RV 171
Query: 502 YHH------EGRYGFREPFEFKSVVDLVCYYS 579
YH+ +G+ F ++ +LV ++S
Sbjct: 172 YHYRINTASDGKLYVSSESRFNTLAELVHHHS 203
>U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene
tyrosine-protein kinase protein.
Length = 1130
Score = 39.1 bits (87), Expect = 0.021
Identities = 24/92 (26%), Positives = 47/92 (51%), Gaps = 6/92 (6%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
+P +SLE WY G ++R+ A L +G+FLVR + + ++++R G ++
Sbjct: 117 TPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEG-----RV 171
Query: 502 YHH------EGRYGFREPFEFKSVVDLVCYYS 579
YH+ +G+ F ++ +LV ++S
Sbjct: 172 YHYRINTASDGKLYVSSESRFNTLAELVHHHS 203
>U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene
tyrosine-protein kinase protein.
Length = 1149
Score = 39.1 bits (87), Expect = 0.021
Identities = 24/92 (26%), Positives = 47/92 (51%), Gaps = 6/92 (6%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
+P +SLE WY G ++R+ A L +G+FLVR + + ++++R G ++
Sbjct: 136 TPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEG-----RV 190
Query: 502 YHH------EGRYGFREPFEFKSVVDLVCYYS 579
YH+ +G+ F ++ +LV ++S
Sbjct: 191 YHYRINTASDGKLYVSSESRFNTLAELVHHHS 222
>M35296-1|AAA35553.1| 1182|Homo sapiens protein ( Human tyrosine
kinase arg gene mRNA. ).
Length = 1182
Score = 39.1 bits (87), Expect = 0.021
Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 6/92 (6%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
+P +SLE WY G ++R A L +G+FLVR + + ++++R G ++
Sbjct: 163 TPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEG-----RV 217
Query: 502 YHH------EGRYGFREPFEFKSVVDLVCYYS 579
YH+ +G+ F ++ +LV ++S
Sbjct: 218 YHYRINTTADGKVYVTAESRFSTLAELVHHHS 249
>DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 39.1 bits (87), Expect = 0.021
Identities = 24/92 (26%), Positives = 47/92 (51%), Gaps = 6/92 (6%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
+P +SLE WY G ++R+ A L +G+FLVR + + ++++R G ++
Sbjct: 136 TPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEG-----RV 190
Query: 502 YHH------EGRYGFREPFEFKSVVDLVCYYS 579
YH+ +G+ F ++ +LV ++S
Sbjct: 191 YHYRINTASDGKLYVSSESRFNTLAELVHHHS 222
>DQ009672-1|AAY16984.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 39.1 bits (87), Expect = 0.021
Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 6/92 (6%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
+P +SLE WY G ++R A L +G+FLVR + + ++++R G ++
Sbjct: 163 TPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEG-----RV 217
Query: 502 YHH------EGRYGFREPFEFKSVVDLVCYYS 579
YH+ +G+ F ++ +LV ++S
Sbjct: 218 YHYRINTTADGKVYVTAESRFSTLAELVHHHS 249
>BX538317-1|CAD98092.1| 1092|Homo sapiens hypothetical protein
protein.
Length = 1092
Score = 39.1 bits (87), Expect = 0.021
Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 6/92 (6%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
+P +SLE WY G ++R A L +G+FLVR + + ++++R G ++
Sbjct: 176 TPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEG-----RV 230
Query: 502 YHH------EGRYGFREPFEFKSVVDLVCYYS 579
YH+ +G+ F ++ +LV ++S
Sbjct: 231 YHYRINTTADGKVYVTAESRFSTLAELVHHHS 262
>BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 39.1 bits (87), Expect = 0.021
Identities = 24/92 (26%), Positives = 47/92 (51%), Gaps = 6/92 (6%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
+P +SLE WY G ++R+ A L +G+FLVR + + ++++R G ++
Sbjct: 136 TPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEG-----RV 190
Query: 502 YHH------EGRYGFREPFEFKSVVDLVCYYS 579
YH+ +G+ F ++ +LV ++S
Sbjct: 191 YHYRINTASDGKLYVSSESRFNTLAELVHHHS 222
>BC065912-1|AAH65912.1| 1167|Homo sapiens ABL2 protein protein.
Length = 1167
Score = 39.1 bits (87), Expect = 0.021
Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 6/92 (6%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
+P +SLE WY G ++R A L +G+FLVR + + ++++R G ++
Sbjct: 148 TPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEG-----RV 202
Query: 502 YHH------EGRYGFREPFEFKSVVDLVCYYS 579
YH+ +G+ F ++ +LV ++S
Sbjct: 203 YHYRINTTADGKVYVTAESRFSTLAELVHHHS 234
>AM491362-1|CAM33012.1| 585|Homo sapiens bcr-abl1 e6a2 chimeric
protein protein.
Length = 585
Score = 39.1 bits (87), Expect = 0.021
Identities = 24/92 (26%), Positives = 47/92 (51%), Gaps = 6/92 (6%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
+P +SLE WY G ++R+ A L +G+FLVR + + ++++R G ++
Sbjct: 456 TPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEG-----RV 510
Query: 502 YHH------EGRYGFREPFEFKSVVDLVCYYS 579
YH+ +G+ F ++ +LV ++S
Sbjct: 511 YHYRINTASDGKLYVSSESRFNTLAELVHHHS 542
>AM491361-1|CAM33011.1| 313|Homo sapiens bcr-abl1 e1a3 chimeric
protein protein.
Length = 313
Score = 39.1 bits (87), Expect = 0.021
Identities = 24/92 (26%), Positives = 47/92 (51%), Gaps = 6/92 (6%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
+P +SLE WY G ++R+ A L +G+FLVR + + ++++R G ++
Sbjct: 184 TPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEG-----RV 238
Query: 502 YHH------EGRYGFREPFEFKSVVDLVCYYS 579
YH+ +G+ F ++ +LV ++S
Sbjct: 239 YHYRINTASDGKLYVSSESRFNTLAELVHHHS 270
>AM491360-1|CAM33010.1| 260|Homo sapiens bcr-abl1 e14a3 chimeric
protein protein.
Length = 260
Score = 39.1 bits (87), Expect = 0.021
Identities = 24/92 (26%), Positives = 47/92 (51%), Gaps = 6/92 (6%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
+P +SLE WY G ++R+ A L +G+FLVR + + ++++R G ++
Sbjct: 131 TPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEG-----RV 185
Query: 502 YHH------EGRYGFREPFEFKSVVDLVCYYS 579
YH+ +G+ F ++ +LV ++S
Sbjct: 186 YHYRINTASDGKLYVSSESRFNTLAELVHHHS 217
>AL512326-6|CAI13570.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 39.1 bits (87), Expect = 0.021
Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 6/92 (6%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
+P +SLE WY G ++R A L +G+FLVR + + ++++R G ++
Sbjct: 163 TPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEG-----RV 217
Query: 502 YHH------EGRYGFREPFEFKSVVDLVCYYS 579
YH+ +G+ F ++ +LV ++S
Sbjct: 218 YHYRINTTADGKVYVTAESRFSTLAELVHHHS 249
>AL512326-2|CAI13566.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 39.1 bits (87), Expect = 0.021
Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 6/92 (6%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
+P +SLE WY G ++R A L +G+FLVR + + ++++R G ++
Sbjct: 148 TPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEG-----RV 202
Query: 502 YHH------EGRYGFREPFEFKSVVDLVCYYS 579
YH+ +G+ F ++ +LV ++S
Sbjct: 203 YHYRINTTADGKVYVTAESRFSTLAELVHHHS 234
>AL359179-2|CAI15585.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 39.1 bits (87), Expect = 0.021
Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 6/92 (6%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
+P +SLE WY G ++R A L +G+FLVR + + ++++R G ++
Sbjct: 163 TPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEG-----RV 217
Query: 502 YHH------EGRYGFREPFEFKSVVDLVCYYS 579
YH+ +G+ F ++ +LV ++S
Sbjct: 218 YHYRINTTADGKVYVTAESRFSTLAELVHHHS 249
>AL359179-1|CAI15584.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 39.1 bits (87), Expect = 0.021
Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 6/92 (6%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
+P +SLE WY G ++R A L +G+FLVR + + ++++R G ++
Sbjct: 148 TPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEG-----RV 202
Query: 502 YHH------EGRYGFREPFEFKSVVDLVCYYS 579
YH+ +G+ F ++ +LV ++S
Sbjct: 203 YHYRINTTADGKVYVTAESRFSTLAELVHHHS 234
>AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 39.1 bits (87), Expect = 0.021
Identities = 24/92 (26%), Positives = 47/92 (51%), Gaps = 6/92 (6%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
+P +SLE WY G ++R+ A L +G+FLVR + + ++++R G ++
Sbjct: 136 TPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEG-----RV 190
Query: 502 YHH------EGRYGFREPFEFKSVVDLVCYYS 579
YH+ +G+ F ++ +LV ++S
Sbjct: 191 YHYRINTASDGKLYVSSESRFNTLAELVHHHS 222
>AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 39.1 bits (87), Expect = 0.021
Identities = 24/92 (26%), Positives = 47/92 (51%), Gaps = 6/92 (6%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
+P +SLE WY G ++R+ A L +G+FLVR + + ++++R G ++
Sbjct: 136 TPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEG-----RV 190
Query: 502 YHH------EGRYGFREPFEFKSVVDLVCYYS 579
YH+ +G+ F ++ +LV ++S
Sbjct: 191 YHYRINTASDGKLYVSSESRFNTLAELVHHHS 222
>AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1130
Score = 39.1 bits (87), Expect = 0.021
Identities = 24/92 (26%), Positives = 47/92 (51%), Gaps = 6/92 (6%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
+P +SLE WY G ++R+ A L +G+FLVR + + ++++R G ++
Sbjct: 117 TPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEG-----RV 171
Query: 502 YHH------EGRYGFREPFEFKSVVDLVCYYS 579
YH+ +G+ F ++ +LV ++S
Sbjct: 172 YHYRINTASDGKLYVSSESRFNTLAELVHHHS 203
>AL139132-5|CAH70925.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 39.1 bits (87), Expect = 0.021
Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 6/92 (6%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
+P +SLE WY G ++R A L +G+FLVR + + ++++R G ++
Sbjct: 163 TPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEG-----RV 217
Query: 502 YHH------EGRYGFREPFEFKSVVDLVCYYS 579
YH+ +G+ F ++ +LV ++S
Sbjct: 218 YHYRINTTADGKVYVTAESRFSTLAELVHHHS 249
>AL139132-1|CAH70921.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 39.1 bits (87), Expect = 0.021
Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 6/92 (6%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
+P +SLE WY G ++R A L +G+FLVR + + ++++R G ++
Sbjct: 148 TPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEG-----RV 202
Query: 502 YHH------EGRYGFREPFEFKSVVDLVCYYS 579
YH+ +G+ F ++ +LV ++S
Sbjct: 203 YHYRINTTADGKVYVTAESRFSTLAELVHHHS 234
>AJ131467-1|CAA10377.1| 307|Homo sapiens BCR/ABL chimeric fusion
peptide protein.
Length = 307
Score = 39.1 bits (87), Expect = 0.021
Identities = 24/92 (26%), Positives = 47/92 (51%), Gaps = 6/92 (6%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
+P +SLE WY G ++R+ A L +G+FLVR + + ++++R G ++
Sbjct: 190 TPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEG-----RV 244
Query: 502 YHH------EGRYGFREPFEFKSVVDLVCYYS 579
YH+ +G+ F ++ +LV ++S
Sbjct: 245 YHYRINTASDGKLYVSSESRFNTLAELVHHHS 276
>AJ131466-1|CAA10376.1| 332|Homo sapiens BCR/ABL (major breakpoint)
fusion peptide protein.
Length = 332
Score = 39.1 bits (87), Expect = 0.021
Identities = 24/92 (26%), Positives = 47/92 (51%), Gaps = 6/92 (6%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
+P +SLE WY G ++R+ A L +G+FLVR + + ++++R G ++
Sbjct: 215 TPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEG-----RV 269
Query: 502 YHH------EGRYGFREPFEFKSVVDLVCYYS 579
YH+ +G+ F ++ +LV ++S
Sbjct: 270 YHYRINTASDGKLYVSSESRFNTLAELVHHHS 301
>AF113911-1|AAD04633.1| 359|Homo sapiens BCR-ABL minor breakpoint
peptide protein.
Length = 359
Score = 39.1 bits (87), Expect = 0.021
Identities = 24/92 (26%), Positives = 47/92 (51%), Gaps = 6/92 (6%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
+P +SLE WY G ++R+ A L +G+FLVR + + ++++R G ++
Sbjct: 242 TPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEG-----RV 296
Query: 502 YHH------EGRYGFREPFEFKSVVDLVCYYS 579
YH+ +G+ F ++ +LV ++S
Sbjct: 297 YHYRINTASDGKLYVSSESRFNTLAELVHHHS 328
>AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 isoform b variant
protein.
Length = 1167
Score = 39.1 bits (87), Expect = 0.021
Identities = 24/92 (26%), Positives = 47/92 (51%), Gaps = 6/92 (6%)
Frame = +1
Query: 322 SPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKI 501
+P +SLE WY G ++R+ A L +G+FLVR + + ++++R G ++
Sbjct: 154 TPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEG-----RV 208
Query: 502 YHH------EGRYGFREPFEFKSVVDLVCYYS 579
YH+ +G+ F ++ +LV ++S
Sbjct: 209 YHYRINTASDGKLYVSSESRFNTLAELVHHHS 240
>AB004904-1|BAA22430.1| 225|Homo sapiens STAT induced STAT
inhibitor-3 protein.
Length = 225
Score = 39.1 bits (87), Expect = 0.021
Identities = 19/65 (29%), Positives = 35/65 (53%)
Frame = +1
Query: 337 LEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEG 516
L+ + +YW +T EAN L GTFL+R++S++ + L+V+ K ++I G
Sbjct: 41 LQESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHFFALSVKTQSGTKNLRIQCEGG 100
Query: 517 RYGFR 531
+ +
Sbjct: 101 SFSLQ 105
>X58957-1|CAA41728.1| 659|Homo sapiens agammaglobulinaemia tyrosine
kinase protein.
Length = 659
Score = 38.7 bits (86), Expect = 0.028
Identities = 28/95 (29%), Positives = 50/95 (52%), Gaps = 8/95 (8%)
Frame = +1
Query: 328 EHSLEAAEWYWGDITRDEANEKLR-DTRDGTFLVRNASNKDSGYTLTV---RKGGANKLI 495
E S+E EWY +TR +A + L+ + ++G F+VR+ S+K YT++V G +I
Sbjct: 273 EDSIEMYEWYSKHMTRSQAEQLLKQEGKEGGFIVRD-SSKAGKYTVSVFAKSTGDPQGVI 331
Query: 496 KIY----HHEGRYGFREPFEFKSVVDLVCYYSEYS 588
+ Y + +Y E F ++ +L+ Y+ S
Sbjct: 332 RHYVVCSTPQSQYYLAEKHLFSTIPELINYHQHNS 366
>U78027-4|AAB64205.1| 659|Homo sapiens Bruton's tyrosine kinase
protein.
Length = 659
Score = 38.7 bits (86), Expect = 0.028
Identities = 28/95 (29%), Positives = 50/95 (52%), Gaps = 8/95 (8%)
Frame = +1
Query: 328 EHSLEAAEWYWGDITRDEANEKLR-DTRDGTFLVRNASNKDSGYTLTV---RKGGANKLI 495
E S+E EWY +TR +A + L+ + ++G F+VR+ S+K YT++V G +I
Sbjct: 273 EDSIEMYEWYSKHMTRSQAEQLLKQEGKEGGFIVRD-SSKAGKYTVSVFAKSTGDPQGVI 331
Query: 496 KIY----HHEGRYGFREPFEFKSVVDLVCYYSEYS 588
+ Y + +Y E F ++ +L+ Y+ S
Sbjct: 332 RHYVVCSTPQSQYYLAEKHLFSTIPELINYHQHNS 366
>U10087-1|AAB60639.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 38.7 bits (86), Expect = 0.028
Identities = 28/95 (29%), Positives = 50/95 (52%), Gaps = 8/95 (8%)
Frame = +1
Query: 328 EHSLEAAEWYWGDITRDEANEKLR-DTRDGTFLVRNASNKDSGYTLTV---RKGGANKLI 495
E S+E EWY +TR +A + L+ + ++G F+VR+ S+K YT++V G +I
Sbjct: 273 EDSIEMYEWYSKHMTRSQAEQLLKQEGKEGGFIVRD-SSKAGKYTVSVFAKSTGDPQGVI 331
Query: 496 KIY----HHEGRYGFREPFEFKSVVDLVCYYSEYS 588
+ Y + +Y E F ++ +L+ Y+ S
Sbjct: 332 RHYVVCSTPQSQYYLAEKHLFSTIPELINYHQHNS 366
>M79321-1|AAB50019.1| 491|Homo sapiens Lyn B protein protein.
Length = 491
Score = 38.7 bits (86), Expect = 0.028
Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 8/98 (8%)
Frame = +1
Query: 331 HSLEAAEWYWGDITRDEANEKL--RDTRDGTFLVRNASNKDSGYTLTVR-----KGGANK 489
++LE EW++ DITR +A +L G FL+R + ++L+VR G K
Sbjct: 101 NTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIK 160
Query: 490 LIKIYH-HEGRYGFREPFEFKSVVDLVCYYSEYSLATC 600
KI G Y F + D++ +Y + + C
Sbjct: 161 HYKIRSLDNGGYYISPRITFPCISDMIKHYQKQADGLC 198
>M16038-1|AAA59540.1| 512|Homo sapiens LYN protein.
Length = 512
Score = 38.7 bits (86), Expect = 0.028
Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 8/98 (8%)
Frame = +1
Query: 331 HSLEAAEWYWGDITRDEANEKL--RDTRDGTFLVRNASNKDSGYTLTVR-----KGGANK 489
++LE EW++ DITR +A +L G FL+R + ++L+VR G K
Sbjct: 122 NTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIK 181
Query: 490 LIKIYH-HEGRYGFREPFEFKSVVDLVCYYSEYSLATC 600
KI G Y F + D++ +Y + + C
Sbjct: 182 HYKIRSLDNGGYYISPRITFPCISDMIKHYQKQADGLC 219
>L31572-1|AAA61479.1| 659|Homo sapiens Bruton agammaglobulinemia
protein.
Length = 659
Score = 38.7 bits (86), Expect = 0.028
Identities = 28/95 (29%), Positives = 50/95 (52%), Gaps = 8/95 (8%)
Frame = +1
Query: 328 EHSLEAAEWYWGDITRDEANEKLR-DTRDGTFLVRNASNKDSGYTLTV---RKGGANKLI 495
E S+E EWY +TR +A + L+ + ++G F+VR+ S+K YT++V G +I
Sbjct: 273 EDSIEMYEWYSKHMTRSQAEQLLKQEGKEGGFIVRD-SSKAGKYTVSVFAKSTGDPQGVI 331
Query: 496 KIY----HHEGRYGFREPFEFKSVVDLVCYYSEYS 588
+ Y + +Y E F ++ +L+ Y+ S
Sbjct: 332 RHYVVCSTPQSQYYLAEKHLFSTIPELINYHQHNS 366
>BC126458-1|AAI26459.1| 512|Homo sapiens LYN protein protein.
Length = 512
Score = 38.7 bits (86), Expect = 0.028
Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 8/98 (8%)
Frame = +1
Query: 331 HSLEAAEWYWGDITRDEANEKL--RDTRDGTFLVRNASNKDSGYTLTVR-----KGGANK 489
++LE EW++ DITR +A +L G FL+R + ++L+VR G K
Sbjct: 122 NTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIK 181
Query: 490 LIKIYH-HEGRYGFREPFEFKSVVDLVCYYSEYSLATC 600
KI G Y F + D++ +Y + + C
Sbjct: 182 HYKIRSLDNGGYYISPRITFPCISDMIKHYQKQADGLC 219
>BC126456-1|AAI26457.1| 512|Homo sapiens LYN protein protein.
Length = 512
Score = 38.7 bits (86), Expect = 0.028
Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 8/98 (8%)
Frame = +1
Query: 331 HSLEAAEWYWGDITRDEANEKL--RDTRDGTFLVRNASNKDSGYTLTVR-----KGGANK 489
++LE EW++ DITR +A +L G FL+R + ++L+VR G K
Sbjct: 122 NTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIK 181
Query: 490 LIKIYH-HEGRYGFREPFEFKSVVDLVCYYSEYSLATC 600
KI G Y F + D++ +Y + + C
Sbjct: 182 HYKIRSLDNGGYYISPRITFPCISDMIKHYQKQADGLC 219
>BC109080-1|AAI09081.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 38.7 bits (86), Expect = 0.028
Identities = 28/95 (29%), Positives = 50/95 (52%), Gaps = 8/95 (8%)
Frame = +1
Query: 328 EHSLEAAEWYWGDITRDEANEKLR-DTRDGTFLVRNASNKDSGYTLTV---RKGGANKLI 495
E S+E EWY +TR +A + L+ + ++G F+VR+ S+K YT++V G +I
Sbjct: 273 EDSIEMYEWYSKHMTRSQAEQLLKQEGKEGGFIVRD-SSKAGKYTVSVFAKSTGDPQGVI 331
Query: 496 KIY----HHEGRYGFREPFEFKSVVDLVCYYSEYS 588
+ Y + +Y E F ++ +L+ Y+ S
Sbjct: 332 RHYVVCSTPQSQYYLAEKHLFSTIPELINYHQHNS 366
>BC109079-1|AAI09080.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 38.7 bits (86), Expect = 0.028
Identities = 28/95 (29%), Positives = 50/95 (52%), Gaps = 8/95 (8%)
Frame = +1
Query: 328 EHSLEAAEWYWGDITRDEANEKLR-DTRDGTFLVRNASNKDSGYTLTV---RKGGANKLI 495
E S+E EWY +TR +A + L+ + ++G F+VR+ S+K YT++V G +I
Sbjct: 273 EDSIEMYEWYSKHMTRSQAEQLLKQEGKEGGFIVRD-SSKAGKYTVSVFAKSTGDPQGVI 331
Query: 496 KIY----HHEGRYGFREPFEFKSVVDLVCYYSEYS 588
+ Y + +Y E F ++ +L+ Y+ S
Sbjct: 332 RHYVVCSTPQSQYYLAEKHLFSTIPELINYHQHNS 366
>BC075002-1|AAH75002.1| 512|Homo sapiens v-yes-1 Yamaguchi sarcoma
viral related oncogene homolog protein.
Length = 512
Score = 38.7 bits (86), Expect = 0.028
Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 8/98 (8%)
Frame = +1
Query: 331 HSLEAAEWYWGDITRDEANEKL--RDTRDGTFLVRNASNKDSGYTLTVR-----KGGANK 489
++LE EW++ DITR +A +L G FL+R + ++L+VR G K
Sbjct: 122 NTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIK 181
Query: 490 LIKIYH-HEGRYGFREPFEFKSVVDLVCYYSEYSLATC 600
KI G Y F + D++ +Y + + C
Sbjct: 182 HYKIRSLDNGGYYISPRITFPCISDMIKHYQKQADGLC 219
>BC075001-1|AAH75001.1| 512|Homo sapiens v-yes-1 Yamaguchi sarcoma
viral related oncogene homolog protein.
Length = 512
Score = 38.7 bits (86), Expect = 0.028
Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 8/98 (8%)
Frame = +1
Query: 331 HSLEAAEWYWGDITRDEANEKL--RDTRDGTFLVRNASNKDSGYTLTVR-----KGGANK 489
++LE EW++ DITR +A +L G FL+R + ++L+VR G K
Sbjct: 122 NTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIK 181
Query: 490 LIKIYH-HEGRYGFREPFEFKSVVDLVCYYSEYSLATC 600
KI G Y F + D++ +Y + + C
Sbjct: 182 HYKIRSLDNGGYYISPRITFPCISDMIKHYQKQADGLC 219
>BC068551-1|AAH68551.1| 582|Homo sapiens LYN protein protein.
Length = 582
Score = 38.7 bits (86), Expect = 0.028
Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 8/98 (8%)
Frame = +1
Query: 331 HSLEAAEWYWGDITRDEANEKL--RDTRDGTFLVRNASNKDSGYTLTVR-----KGGANK 489
++LE EW++ DITR +A +L G FL+R + ++L+VR G K
Sbjct: 192 NTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIK 251
Query: 490 LIKIYH-HEGRYGFREPFEFKSVVDLVCYYSEYSLATC 600
KI G Y F + D++ +Y + + C
Sbjct: 252 HYKIRSLDNGGYYISPRITFPCISDMIKHYQKQADGLC 289
>BC059394-1|AAH59394.1| 582|Homo sapiens LYN protein protein.
Length = 582
Score = 38.7 bits (86), Expect = 0.028
Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 8/98 (8%)
Frame = +1
Query: 331 HSLEAAEWYWGDITRDEANEKL--RDTRDGTFLVRNASNKDSGYTLTVR-----KGGANK 489
++LE EW++ DITR +A +L G FL+R + ++L+VR G K
Sbjct: 192 NTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIK 251
Query: 490 LIKIYH-HEGRYGFREPFEFKSVVDLVCYYSEYSLATC 600
KI G Y F + D++ +Y + + C
Sbjct: 252 HYKIRSLDNGGYYISPRITFPCISDMIKHYQKQADGLC 289
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 105,875,366
Number of Sequences: 237096
Number of extensions: 2090701
Number of successful extensions: 11521
Number of sequences better than 10.0: 382
Number of HSP's better than 10.0 without gapping: 11213
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 11430
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11437206932
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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