Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP22_F_E04
(883 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Z14093-1|CAA78475.1| 445|Homo sapiens branched chain decarboxyl... 263 7e-70
S62652-1|AAB20222.2| 443|Homo sapiens branched-chain alpha-keto... 263 7e-70
S38327-1|AAB19268.2| 387|Homo sapiens protein ( branched-chain ... 263 7e-70
J04474-1|AAB59549.1| 444|Homo sapiens branched-chain alpha-keto... 263 7e-70
BC023983-1|AAH23983.1| 445|Homo sapiens branched chain keto aci... 263 7e-70
BC008933-1|AAH08933.1| 445|Homo sapiens branched chain keto aci... 263 7e-70
BC007878-1|AAH07878.1| 445|Homo sapiens branched chain keto aci... 263 7e-70
AK127598-1|BAC87051.1| 479|Homo sapiens 1.2.4.4). protein. 263 7e-70
AB209828-1|BAD93065.1| 444|Homo sapiens branched chain keto aci... 260 4e-69
M22221-1|AAA35590.1| 378|Homo sapiens protein ( Human branched-... 248 2e-65
M86808-1|AAA60232.1| 388|Homo sapiens pyruvate dehydrogenase co... 47 1e-04
BC127638-1|AAI27639.1| 388|Homo sapiens pyruvate dehydrogenase ... 47 1e-04
BC127637-1|AAI27638.1| 388|Homo sapiens pyruvate dehydrogenase ... 47 1e-04
BC119657-1|AAI19658.1| 388|Homo sapiens pyruvate dehydrogenase ... 47 1e-04
BC119656-1|AAI19657.1| 388|Homo sapiens pyruvate dehydrogenase ... 47 1e-04
BC094760-1|AAH94760.1| 407|Homo sapiens PDHA2 protein protein. 47 1e-04
BC030697-1|AAH30697.3| 388|Homo sapiens pyruvate dehydrogenase ... 47 1e-04
BC066953-1|AAH66953.2| 388|Homo sapiens pyruvate dehydrogenase ... 45 3e-04
X52710-1|CAA36934.1| 390|Homo sapiens protein ( Human mRNA for ... 44 6e-04
X52709-1|CAA36933.1| 390|Homo sapiens protein ( Human mRNA for ... 44 6e-04
M27257-1|AAA60051.1| 390|Homo sapiens pyruvate dehydrogenase E1... 44 6e-04
M24848-1|AAA36533.1| 390|Homo sapiens protein ( Human pyruvate ... 44 6e-04
L13318-1|AAA60227.1| 390|Homo sapiens pyruvate dehydrogenase E1... 44 6e-04
J03575-1|AAA60050.1| 390|Homo sapiens pyruvate dehydrogenase al... 44 6e-04
J03503-1|AAA60055.1| 414|Homo sapiens PDHA1 protein. 44 6e-04
EF590117-1|ABQ59099.1| 428|Homo sapiens mitochondrial PDHA1 pro... 44 6e-04
D90084-1|BAA14121.1| 390|Homo sapiens pyruvate dehydrogenase al... 44 6e-04
BC002406-1|AAH02406.1| 390|Homo sapiens pyruvate dehydrogenase ... 44 6e-04
AL732326-7|CAI41291.1| 390|Homo sapiens pyruvate dehydrogenase ... 44 6e-04
AK222988-1|BAD96708.1| 390|Homo sapiens pyruvate dehydrogenase ... 44 6e-04
AK222740-1|BAD96460.1| 390|Homo sapiens pyruvate dehydrogenase ... 44 6e-04
L48690-1|AAB59581.1| 390|Homo sapiens pyruvate dehydrogenase E1... 43 0.001
AL732326-6|CAI41290.1| 204|Homo sapiens pyruvate dehydrogenase ... 39 0.028
AL732326-5|CAI41289.1| 180|Homo sapiens pyruvate dehydrogenase ... 35 0.45
AL732326-4|CAI41288.1| 205|Homo sapiens pyruvate dehydrogenase ... 35 0.45
CR541928-1|CAG46726.1| 274|Homo sapiens CCS protein. 32 2.4
BC112055-1|AAI12056.1| 274|Homo sapiens copper chaperone for su... 32 2.4
BC105016-1|AAI05017.1| 274|Homo sapiens copper chaperone for su... 32 2.4
AY113179-1|AAM50090.1| 274|Homo sapiens superoxide dismutase co... 32 2.4
AF002210-1|AAC51764.1| 274|Homo sapiens copper chaperone for su... 32 2.4
EF576990-1|ABQ58815.1| 261|Homo sapiens PDHA1 protein. 32 3.2
AM746210-1|CAN88919.1| 302|Homo sapiens PDHA1/LOC79064 protein ... 32 3.2
L23808-1|AAA58658.1| 470|Homo sapiens metalloproteinase protein. 30 9.7
BC112301-1|AAI12302.1| 470|Homo sapiens matrix metalloproteinas... 30 9.7
AY856072-1|AAW29944.1| 470|Homo sapiens matrix metalloproteinas... 30 9.7
>Z14093-1|CAA78475.1| 445|Homo sapiens branched chain decarboxylase
alpha subunit protein.
Length = 445
Score = 263 bits (644), Expect = 7e-70
Identities = 129/237 (54%), Positives = 154/237 (64%)
Frame = +2
Query: 173 EFPGARAPYVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQL 352
+FPGA A ++ +++F IPIYRVMD GQII+ +E+P+L K ++ +YK+M L
Sbjct: 53 QFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLL 112
Query: 353 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 532
+ MD+ILYESQRQGRISFYMTNYGEEG H+GSA+AL DLVF QYRE GV +YR +
Sbjct: 113 NTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLE 172
Query: 533 ELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPE*RPX 712
+ QCYGN D GKGRQMPVHYG K + VTISSPL TQ+PQAVGAAYA KR R
Sbjct: 173 LFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANR-V 231
Query: 713 XXXXXXXXXXXXXXXXXXFQLCRYVRLSCYMLCRNNGYAISTPPSEQYXGDGIASXG 883
F + CRNNGYAISTP SEQY GDGIA+ G
Sbjct: 232 VICYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARG 288
>S62652-1|AAB20222.2| 443|Homo sapiens branched-chain alpha-keto
acid dehydrogenase E1 alpha subunit protein.
Length = 443
Score = 263 bits (644), Expect = 7e-70
Identities = 129/237 (54%), Positives = 154/237 (64%)
Frame = +2
Query: 173 EFPGARAPYVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQL 352
+FPGA A ++ +++F IPIYRVMD GQII+ +E+P+L K ++ +YK+M L
Sbjct: 51 QFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLL 110
Query: 353 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 532
+ MD+ILYESQRQGRISFYMTNYGEEG H+GSA+AL DLVF QYRE GV +YR +
Sbjct: 111 NTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLE 170
Query: 533 ELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPE*RPX 712
+ QCYGN D GKGRQMPVHYG K + VTISSPL TQ+PQAVGAAYA KR R
Sbjct: 171 LFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANR-V 229
Query: 713 XXXXXXXXXXXXXXXXXXFQLCRYVRLSCYMLCRNNGYAISTPPSEQYXGDGIASXG 883
F + CRNNGYAISTP SEQY GDGIA+ G
Sbjct: 230 VICYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARG 286
>S38327-1|AAB19268.2| 387|Homo sapiens protein ( branched-chain
alpha-keto acid dehydrogenase complex E1 alpha subunit
[human, Genomic, 195 nt, segment 8 of 8]. ).
Length = 387
Score = 263 bits (644), Expect = 7e-70
Identities = 129/237 (54%), Positives = 154/237 (64%)
Frame = +2
Query: 173 EFPGARAPYVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQL 352
+FPGA A ++ +++F IPIYRVMD GQII+ +E+P+L K ++ +YK+M L
Sbjct: 51 QFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLL 110
Query: 353 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 532
+ MD+ILYESQRQGRISFYMTNYGEEG H+GSA+AL DLVF QYRE GV +YR +
Sbjct: 111 NTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLE 170
Query: 533 ELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPE*RPX 712
+ QCYGN D GKGRQMPVHYG K + VTISSPL TQ+PQAVGAAYA KR R
Sbjct: 171 LFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANR-V 229
Query: 713 XXXXXXXXXXXXXXXXXXFQLCRYVRLSCYMLCRNNGYAISTPPSEQYXGDGIASXG 883
F + CRNNGYAISTP SEQY GDGIA+ G
Sbjct: 230 VICYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARG 286
>J04474-1|AAB59549.1| 444|Homo sapiens branched-chain alpha-keto
acid dehydrogenase protein.
Length = 444
Score = 263 bits (644), Expect = 7e-70
Identities = 129/237 (54%), Positives = 154/237 (64%)
Frame = +2
Query: 173 EFPGARAPYVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQL 352
+FPGA A ++ +++F IPIYRVMD GQII+ +E+P+L K ++ +YK+M L
Sbjct: 52 QFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLL 111
Query: 353 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 532
+ MD+ILYESQRQGRISFYMTNYGEEG H+GSA+AL DLVF QYRE GV +YR +
Sbjct: 112 NTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLE 171
Query: 533 ELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPE*RPX 712
+ QCYGN D GKGRQMPVHYG K + VTISSPL TQ+PQAVGAAYA KR R
Sbjct: 172 LFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANR-V 230
Query: 713 XXXXXXXXXXXXXXXXXXFQLCRYVRLSCYMLCRNNGYAISTPPSEQYXGDGIASXG 883
F + CRNNGYAISTP SEQY GDGIA+ G
Sbjct: 231 VICYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARG 287
>BC023983-1|AAH23983.1| 445|Homo sapiens branched chain keto acid
dehydrogenase E1, alpha polypeptide protein.
Length = 445
Score = 263 bits (644), Expect = 7e-70
Identities = 129/237 (54%), Positives = 154/237 (64%)
Frame = +2
Query: 173 EFPGARAPYVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQL 352
+FPGA A ++ +++F IPIYRVMD GQII+ +E+P+L K ++ +YK+M L
Sbjct: 53 QFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLL 112
Query: 353 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 532
+ MD+ILYESQRQGRISFYMTNYGEEG H+GSA+AL DLVF QYRE GV +YR +
Sbjct: 113 NTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLE 172
Query: 533 ELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPE*RPX 712
+ QCYGN D GKGRQMPVHYG K + VTISSPL TQ+PQAVGAAYA KR R
Sbjct: 173 LFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANR-V 231
Query: 713 XXXXXXXXXXXXXXXXXXFQLCRYVRLSCYMLCRNNGYAISTPPSEQYXGDGIASXG 883
F + CRNNGYAISTP SEQY GDGIA+ G
Sbjct: 232 VICYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARG 288
>BC008933-1|AAH08933.1| 445|Homo sapiens branched chain keto acid
dehydrogenase E1, alpha polypeptide protein.
Length = 445
Score = 263 bits (644), Expect = 7e-70
Identities = 129/237 (54%), Positives = 154/237 (64%)
Frame = +2
Query: 173 EFPGARAPYVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQL 352
+FPGA A ++ +++F IPIYRVMD GQII+ +E+P+L K ++ +YK+M L
Sbjct: 53 QFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLL 112
Query: 353 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 532
+ MD+ILYESQRQGRISFYMTNYGEEG H+GSA+AL DLVF QYRE GV +YR +
Sbjct: 113 NTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLE 172
Query: 533 ELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPE*RPX 712
+ QCYGN D GKGRQMPVHYG K + VTISSPL TQ+PQAVGAAYA KR R
Sbjct: 173 LFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANR-V 231
Query: 713 XXXXXXXXXXXXXXXXXXFQLCRYVRLSCYMLCRNNGYAISTPPSEQYXGDGIASXG 883
F + CRNNGYAISTP SEQY GDGIA+ G
Sbjct: 232 VICYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARG 288
>BC007878-1|AAH07878.1| 445|Homo sapiens branched chain keto acid
dehydrogenase E1, alpha polypeptide protein.
Length = 445
Score = 263 bits (644), Expect = 7e-70
Identities = 129/237 (54%), Positives = 154/237 (64%)
Frame = +2
Query: 173 EFPGARAPYVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQL 352
+FPGA A ++ +++F IPIYRVMD GQII+ +E+P+L K ++ +YK+M L
Sbjct: 53 QFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLL 112
Query: 353 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 532
+ MD+ILYESQRQGRISFYMTNYGEEG H+GSA+AL DLVF QYRE GV +YR +
Sbjct: 113 NTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLE 172
Query: 533 ELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPE*RPX 712
+ QCYGN D GKGRQMPVHYG K + VTISSPL TQ+PQAVGAAYA KR R
Sbjct: 173 LFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANR-V 231
Query: 713 XXXXXXXXXXXXXXXXXXFQLCRYVRLSCYMLCRNNGYAISTPPSEQYXGDGIASXG 883
F + CRNNGYAISTP SEQY GDGIA+ G
Sbjct: 232 VICYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARG 288
>AK127598-1|BAC87051.1| 479|Homo sapiens 1.2.4.4). protein.
Length = 479
Score = 263 bits (644), Expect = 7e-70
Identities = 129/237 (54%), Positives = 154/237 (64%)
Frame = +2
Query: 173 EFPGARAPYVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQL 352
+FPGA A ++ +++F IPIYRVMD GQII+ +E+P+L K ++ +YK+M L
Sbjct: 87 QFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLL 146
Query: 353 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 532
+ MD+ILYESQRQGRISFYMTNYGEEG H+GSA+AL DLVF QYRE GV +YR +
Sbjct: 147 NTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLE 206
Query: 533 ELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPE*RPX 712
+ QCYGN D GKGRQMPVHYG K + VTISSPL TQ+PQAVGAAYA KR R
Sbjct: 207 LFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANR-V 265
Query: 713 XXXXXXXXXXXXXXXXXXFQLCRYVRLSCYMLCRNNGYAISTPPSEQYXGDGIASXG 883
F + CRNNGYAISTP SEQY GDGIA+ G
Sbjct: 266 VICYFGGGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARG 322
>AB209828-1|BAD93065.1| 444|Homo sapiens branched chain keto acid
dehydrogenase E1, alpha polypeptide variant protein.
Length = 444
Score = 260 bits (638), Expect = 4e-69
Identities = 128/234 (54%), Positives = 152/234 (64%)
Frame = +2
Query: 173 EFPGARAPYVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQL 352
+FPGA A ++ +++F IPIYRVMD GQII+ +E+P+L K ++ +YK+M L
Sbjct: 53 QFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLL 112
Query: 353 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 532
+ MD+ILYESQRQGRISFYMTNYGEEG H+GSA+AL DLVF QYRE GV +YR +
Sbjct: 113 NTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLE 172
Query: 533 ELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPE*RPX 712
+ QCYGN D GKGRQMPVHYG K + VTISSPL TQ+PQAVGAAYA KR R
Sbjct: 173 LFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANR-V 231
Query: 713 XXXXXXXXXXXXXXXXXXFQLCRYVRLSCYMLCRNNGYAISTPPSEQYXGDGIA 874
F + CRNNGYAISTP SEQY GDGIA
Sbjct: 232 VICYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIA 285
>M22221-1|AAA35590.1| 378|Homo sapiens protein ( Human
branched-chain alpha-keto acid dehydrogenase E1-alpha
subunit (BCKDH) mRNA, partial cds. ).
Length = 378
Score = 248 bits (607), Expect = 2e-65
Identities = 123/214 (57%), Positives = 142/214 (66%)
Frame = +2
Query: 242 IPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQLSHMDKILYESQRQGRISFYMTNY 421
IPIYRVMD GQII+ +E+P+L K ++ +YK+M L+ MD+ILYESQRQGRISFYMTNY
Sbjct: 9 IPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLLNTMDRILYESQRQGRISFYMTNY 68
Query: 422 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 601
GEEG H+GSA+AL DLVF QYRE GV +YR + + QCYGN D GKGRQMPVHY
Sbjct: 69 GEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLELFMAQCYGNISDLGKGRQMPVHY 128
Query: 602 GSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPE*RPXXXXXXXXXXXXXXXXXXXFQLCR 781
G K + VTISSPL TQ+PQAVGAAYA KR R F
Sbjct: 129 GCKERHFVTISSPLATQIPQAVGAAYAAKRANANR-VVICYFGEGAASEGDAHDGFNFAA 187
Query: 782 YVRLSCYMLCRNNGYAISTPPSEQYXGDGIASXG 883
+ CRNNGYAISTP SEQY GDGIA+ G
Sbjct: 188 TLECPIIFFCRNNGYAISTPTSEQYRGDGIAARG 221
>M86808-1|AAA60232.1| 388|Homo sapiens pyruvate dehydrogenase
complex protein.
Length = 388
Score = 46.8 bits (106), Expect = 1e-04
Identities = 42/179 (23%), Positives = 70/179 (39%), Gaps = 1/179 (0%)
Frame = +2
Query: 305 LDKATLINMYKTMVQLSHMDKILYESQRQGRI-SFYMTNYGEEGIHIGSASALSPKDLVF 481
L +A + Y+ M+ + M+ + +Q I F G+E +G + ++P D V
Sbjct: 54 LTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVI 113
Query: 482 SQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQ 661
+ YR GV RG++V ++ + G KG+ +H +K N + +G Q P
Sbjct: 114 TSYRAHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYTK--NFYGGNGIVGAQGPL 171
Query: 662 AVGAAYAYKRVPE*RPXXXXXXXXXXXXXXXXXXXFQLCRYVRLSCYMLCRNNGYAIST 838
G A A K F + +L C +C NN Y + T
Sbjct: 172 GAGIALACKYKGN-DEICLTLYGDGAANQGQIAEAFNMAALWKLPCVFICENNLYGMGT 229
Score = 35.9 bits (79), Expect = 0.19
Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 2/41 (4%)
Frame = +3
Query: 690 EFPNNDRCVICYFGDGAASEGDAHAAFNFAA--TLDCPVIC 806
++ ND + +GDGAA++G AFN AA L C IC
Sbjct: 180 KYKGNDEICLTLYGDGAANQGQIAEAFNMAALWKLPCVFIC 220
>BC127638-1|AAI27639.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 46.8 bits (106), Expect = 1e-04
Identities = 42/179 (23%), Positives = 70/179 (39%), Gaps = 1/179 (0%)
Frame = +2
Query: 305 LDKATLINMYKTMVQLSHMDKILYESQRQGRI-SFYMTNYGEEGIHIGSASALSPKDLVF 481
L +A + Y+ M+ + M+ + +Q I F G+E +G + ++P D V
Sbjct: 54 LTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVI 113
Query: 482 SQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQ 661
+ YR GV RG++V ++ + G KG+ +H +K N + +G Q P
Sbjct: 114 TSYRAHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYTK--NFYGGNGIVGAQGPL 171
Query: 662 AVGAAYAYKRVPE*RPXXXXXXXXXXXXXXXXXXXFQLCRYVRLSCYMLCRNNGYAIST 838
G A A K F + +L C +C NN Y + T
Sbjct: 172 GAGIALACKYKGN-DEICLTLYGDGAANQGQIAEAFNMAALWKLPCVFICENNLYGMGT 229
Score = 35.9 bits (79), Expect = 0.19
Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 2/41 (4%)
Frame = +3
Query: 690 EFPNNDRCVICYFGDGAASEGDAHAAFNFAA--TLDCPVIC 806
++ ND + +GDGAA++G AFN AA L C IC
Sbjct: 180 KYKGNDEICLTLYGDGAANQGQIAEAFNMAALWKLPCVFIC 220
>BC127637-1|AAI27638.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 46.8 bits (106), Expect = 1e-04
Identities = 42/179 (23%), Positives = 70/179 (39%), Gaps = 1/179 (0%)
Frame = +2
Query: 305 LDKATLINMYKTMVQLSHMDKILYESQRQGRI-SFYMTNYGEEGIHIGSASALSPKDLVF 481
L +A + Y+ M+ + M+ + +Q I F G+E +G + ++P D V
Sbjct: 54 LTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVI 113
Query: 482 SQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQ 661
+ YR GV RG++V ++ + G KG+ +H +K N + +G Q P
Sbjct: 114 TSYRAHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYTK--NFYGGNGIVGAQGPL 171
Query: 662 AVGAAYAYKRVPE*RPXXXXXXXXXXXXXXXXXXXFQLCRYVRLSCYMLCRNNGYAIST 838
G A A K F + +L C +C NN Y + T
Sbjct: 172 GAGIALACKYKGN-DEICLTLYGDGAANQGQIAEAFNMAALWKLPCVFICENNLYGMGT 229
Score = 35.9 bits (79), Expect = 0.19
Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 2/41 (4%)
Frame = +3
Query: 690 EFPNNDRCVICYFGDGAASEGDAHAAFNFAA--TLDCPVIC 806
++ ND + +GDGAA++G AFN AA L C IC
Sbjct: 180 KYKGNDEICLTLYGDGAANQGQIAEAFNMAALWKLPCVFIC 220
>BC119657-1|AAI19658.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 46.8 bits (106), Expect = 1e-04
Identities = 42/179 (23%), Positives = 70/179 (39%), Gaps = 1/179 (0%)
Frame = +2
Query: 305 LDKATLINMYKTMVQLSHMDKILYESQRQGRI-SFYMTNYGEEGIHIGSASALSPKDLVF 481
L +A + Y+ M+ + M+ + +Q I F G+E +G + ++P D V
Sbjct: 54 LTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVI 113
Query: 482 SQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQ 661
+ YR GV RG++V ++ + G KG+ +H +K N + +G Q P
Sbjct: 114 TSYRAHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYTK--NFYGGNGIVGAQGPL 171
Query: 662 AVGAAYAYKRVPE*RPXXXXXXXXXXXXXXXXXXXFQLCRYVRLSCYMLCRNNGYAIST 838
G A A K F + +L C +C NN Y + T
Sbjct: 172 GAGIALACKYKGN-DEICLTLYGDGAANQGQIAEAFNMAALWKLPCVFICENNLYGMGT 229
Score = 35.9 bits (79), Expect = 0.19
Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 2/41 (4%)
Frame = +3
Query: 690 EFPNNDRCVICYFGDGAASEGDAHAAFNFAA--TLDCPVIC 806
++ ND + +GDGAA++G AFN AA L C IC
Sbjct: 180 KYKGNDEICLTLYGDGAANQGQIAEAFNMAALWKLPCVFIC 220
>BC119656-1|AAI19657.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 46.8 bits (106), Expect = 1e-04
Identities = 42/179 (23%), Positives = 70/179 (39%), Gaps = 1/179 (0%)
Frame = +2
Query: 305 LDKATLINMYKTMVQLSHMDKILYESQRQGRI-SFYMTNYGEEGIHIGSASALSPKDLVF 481
L +A + Y+ M+ + M+ + +Q I F G+E +G + ++P D V
Sbjct: 54 LTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVI 113
Query: 482 SQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQ 661
+ YR GV RG++V ++ + G KG+ +H +K N + +G Q P
Sbjct: 114 TSYRAHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYTK--NFYGGNGIVGAQGPL 171
Query: 662 AVGAAYAYKRVPE*RPXXXXXXXXXXXXXXXXXXXFQLCRYVRLSCYMLCRNNGYAIST 838
G A A K F + +L C +C NN Y + T
Sbjct: 172 GAGIALACKYKGN-DEICLTLYGDGAANQGQIAEAFNMAALWKLPCVFICENNLYGMGT 229
Score = 35.9 bits (79), Expect = 0.19
Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 2/41 (4%)
Frame = +3
Query: 690 EFPNNDRCVICYFGDGAASEGDAHAAFNFAA--TLDCPVIC 806
++ ND + +GDGAA++G AFN AA L C IC
Sbjct: 180 KYKGNDEICLTLYGDGAANQGQIAEAFNMAALWKLPCVFIC 220
>BC094760-1|AAH94760.1| 407|Homo sapiens PDHA2 protein protein.
Length = 407
Score = 46.8 bits (106), Expect = 1e-04
Identities = 42/179 (23%), Positives = 70/179 (39%), Gaps = 1/179 (0%)
Frame = +2
Query: 305 LDKATLINMYKTMVQLSHMDKILYESQRQGRI-SFYMTNYGEEGIHIGSASALSPKDLVF 481
L +A + Y+ M+ + M+ + +Q I F G+E +G + ++P D V
Sbjct: 73 LTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVI 132
Query: 482 SQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQ 661
+ YR GV RG++V ++ + G KG+ +H +K N + +G Q P
Sbjct: 133 TSYRAHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYTK--NFYGGNGIVGAQGPL 190
Query: 662 AVGAAYAYKRVPE*RPXXXXXXXXXXXXXXXXXXXFQLCRYVRLSCYMLCRNNGYAIST 838
G A A K F + +L C +C NN Y + T
Sbjct: 191 GAGIALACKYKGN-DEICLTLYGDGAANQGQIAEAFNMAALWKLPCVFICENNLYGMGT 248
Score = 35.9 bits (79), Expect = 0.19
Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 2/41 (4%)
Frame = +3
Query: 690 EFPNNDRCVICYFGDGAASEGDAHAAFNFAA--TLDCPVIC 806
++ ND + +GDGAA++G AFN AA L C IC
Sbjct: 199 KYKGNDEICLTLYGDGAANQGQIAEAFNMAALWKLPCVFIC 239
>BC030697-1|AAH30697.3| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 46.8 bits (106), Expect = 1e-04
Identities = 42/179 (23%), Positives = 70/179 (39%), Gaps = 1/179 (0%)
Frame = +2
Query: 305 LDKATLINMYKTMVQLSHMDKILYESQRQGRI-SFYMTNYGEEGIHIGSASALSPKDLVF 481
L +A + Y+ M+ + M+ + +Q I F G+E +G + ++P D V
Sbjct: 54 LTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVI 113
Query: 482 SQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQ 661
+ YR GV RG++V ++ + G KG+ +H +K N + +G Q P
Sbjct: 114 TSYRAHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYTK--NFYGGNGIVGAQGPL 171
Query: 662 AVGAAYAYKRVPE*RPXXXXXXXXXXXXXXXXXXXFQLCRYVRLSCYMLCRNNGYAIST 838
G A A K F + +L C +C NN Y + T
Sbjct: 172 GAGIALACKYKGN-DEICLTLYGDGAANQGQIAEAFNMAALWKLPCVFICENNLYGMGT 229
Score = 35.9 bits (79), Expect = 0.19
Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 2/41 (4%)
Frame = +3
Query: 690 EFPNNDRCVICYFGDGAASEGDAHAAFNFAA--TLDCPVIC 806
++ ND + +GDGAA++G AFN AA L C IC
Sbjct: 180 KYKGNDEICLTLYGDGAANQGQIAEAFNMAALWKLPCVFIC 220
>BC066953-1|AAH66953.2| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 45.2 bits (102), Expect = 3e-04
Identities = 42/179 (23%), Positives = 69/179 (38%), Gaps = 1/179 (0%)
Frame = +2
Query: 305 LDKATLINMYKTMVQLSHMDKILYESQRQGRI-SFYMTNYGEEGIHIGSASALSPKDLVF 481
L +A + Y+ M+ + M+ + +Q I F G+E +G + ++P D V
Sbjct: 54 LTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVI 113
Query: 482 SQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQ 661
+ YR GV RG +V ++ + G KG+ +H +K N + +G Q P
Sbjct: 114 TSYRAHGVCYTRGPSVRSILAELTGRRGGCAKGKGGSMHMYTK--NFYGGNGIVGAQGPL 171
Query: 662 AVGAAYAYKRVPE*RPXXXXXXXXXXXXXXXXXXXFQLCRYVRLSCYMLCRNNGYAIST 838
G A A K F + +L C +C NN Y + T
Sbjct: 172 GAGIALACKYKGN-DEICLTLYGDGAANQGQIAEAFNMAALWKLPCVFICENNLYGMGT 229
Score = 35.9 bits (79), Expect = 0.19
Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 2/41 (4%)
Frame = +3
Query: 690 EFPNNDRCVICYFGDGAASEGDAHAAFNFAA--TLDCPVIC 806
++ ND + +GDGAA++G AFN AA L C IC
Sbjct: 180 KYKGNDEICLTLYGDGAANQGQIAEAFNMAALWKLPCVFIC 220
>X52710-1|CAA36934.1| 390|Homo sapiens protein ( Human mRNA for
liver pyruvate dehydrogenase (EC 1.2.4.1) E1' subunit.
).
Length = 390
Score = 44.4 bits (100), Expect = 6e-04
Identities = 32/139 (23%), Positives = 56/139 (40%)
Frame = +2
Query: 422 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 601
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 602 GSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPE*RPXXXXXXXXXXXXXXXXXXXFQLCR 781
+K N + +G Q+P G A A K + + +
Sbjct: 156 YAK--NFYGGNGIVGAQVPLGAGIALACKYNGK-DEVCLTLYGDGAANQGQIFEAYNMAA 212
Query: 782 YVRLSCYMLCRNNGYAIST 838
+L C +C NN Y + T
Sbjct: 213 LWKLPCIFICENNRYGMGT 231
Score = 31.9 bits (69), Expect = 3.2
Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 2/41 (4%)
Frame = +3
Query: 690 EFPNNDRCVICYFGDGAASEGDAHAAFNFAA--TLDCPVIC 806
++ D + +GDGAA++G A+N AA L C IC
Sbjct: 182 KYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFIC 222
>X52709-1|CAA36933.1| 390|Homo sapiens protein ( Human mRNA for
brain pyruvate dehydrogenase (EC 1.2.4.1). ).
Length = 390
Score = 44.4 bits (100), Expect = 6e-04
Identities = 32/139 (23%), Positives = 56/139 (40%)
Frame = +2
Query: 422 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 601
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 602 GSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPE*RPXXXXXXXXXXXXXXXXXXXFQLCR 781
+K N + +G Q+P G A A K + + +
Sbjct: 156 YAK--NFYGGNGIVGAQVPLGAGIALACKYNGK-DEVCLTLYGDGAANQGQIFEAYNMAA 212
Query: 782 YVRLSCYMLCRNNGYAIST 838
+L C +C NN Y + T
Sbjct: 213 LWKLPCIFICENNRYGMGT 231
Score = 31.9 bits (69), Expect = 3.2
Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 2/41 (4%)
Frame = +3
Query: 690 EFPNNDRCVICYFGDGAASEGDAHAAFNFAA--TLDCPVIC 806
++ D + +GDGAA++G A+N AA L C IC
Sbjct: 182 KYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFIC 222
>M27257-1|AAA60051.1| 390|Homo sapiens pyruvate dehydrogenase
E1-alpha subunit protein.
Length = 390
Score = 44.4 bits (100), Expect = 6e-04
Identities = 32/139 (23%), Positives = 56/139 (40%)
Frame = +2
Query: 422 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 601
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 602 GSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPE*RPXXXXXXXXXXXXXXXXXXXFQLCR 781
+K N + +G Q+P G A A K + + +
Sbjct: 156 YAK--NFYGGNGIVGAQVPLGAGIALACKYNGK-DEVCLTLYGDGAANQGQIFEAYNMAA 212
Query: 782 YVRLSCYMLCRNNGYAIST 838
+L C +C NN Y + T
Sbjct: 213 LWKLPCIFICENNRYGMGT 231
Score = 31.9 bits (69), Expect = 3.2
Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 2/41 (4%)
Frame = +3
Query: 690 EFPNNDRCVICYFGDGAASEGDAHAAFNFAA--TLDCPVIC 806
++ D + +GDGAA++G A+N AA L C IC
Sbjct: 182 KYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFIC 222
>M24848-1|AAA36533.1| 390|Homo sapiens protein ( Human pyruvate
dehydrogenase alpha subunit mRNA, complete cds. ).
Length = 390
Score = 44.4 bits (100), Expect = 6e-04
Identities = 32/139 (23%), Positives = 56/139 (40%)
Frame = +2
Query: 422 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 601
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 602 GSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPE*RPXXXXXXXXXXXXXXXXXXXFQLCR 781
+K N + +G Q+P G A A K + + +
Sbjct: 156 YAK--NFYGGNGIVGAQVPLGAGIALACKYNGK-DEVCLTLYGDGAANQGQIFEAYNMAA 212
Query: 782 YVRLSCYMLCRNNGYAIST 838
+L C +C NN Y + T
Sbjct: 213 LWKLPCIFICENNRYGMGT 231
Score = 31.9 bits (69), Expect = 3.2
Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 2/41 (4%)
Frame = +3
Query: 690 EFPNNDRCVICYFGDGAASEGDAHAAFNFAA--TLDCPVIC 806
++ D + +GDGAA++G A+N AA L C IC
Sbjct: 182 KYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFIC 222
>L13318-1|AAA60227.1| 390|Homo sapiens pyruvate dehydrogenase
E1-alpha subunit protein.
Length = 390
Score = 44.4 bits (100), Expect = 6e-04
Identities = 32/139 (23%), Positives = 56/139 (40%)
Frame = +2
Query: 422 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 601
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 602 GSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPE*RPXXXXXXXXXXXXXXXXXXXFQLCR 781
+K N + +G Q+P G A A K + + +
Sbjct: 156 YAK--NFYGGNGIVGAQVPLGAGIALACKYNGK-DEVCLTLYGDGAANQGQIFEAYNMAA 212
Query: 782 YVRLSCYMLCRNNGYAIST 838
+L C +C NN Y + T
Sbjct: 213 LWKLPCIFICENNRYGMGT 231
Score = 31.9 bits (69), Expect = 3.2
Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 2/41 (4%)
Frame = +3
Query: 690 EFPNNDRCVICYFGDGAASEGDAHAAFNFAA--TLDCPVIC 806
++ D + +GDGAA++G A+N AA L C IC
Sbjct: 182 KYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFIC 222
>J03575-1|AAA60050.1| 390|Homo sapiens pyruvate dehydrogenase alpha
subunit protein.
Length = 390
Score = 44.4 bits (100), Expect = 6e-04
Identities = 32/139 (23%), Positives = 56/139 (40%)
Frame = +2
Query: 422 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 601
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 602 GSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPE*RPXXXXXXXXXXXXXXXXXXXFQLCR 781
+K N + +G Q+P G A A K + + +
Sbjct: 156 YAK--NFYGGNGIVGAQVPLGAGIALACKYNGK-DEVCLTLYGDGAANQGQIFEAYNMAA 212
Query: 782 YVRLSCYMLCRNNGYAIST 838
+L C +C NN Y + T
Sbjct: 213 LWKLPCIFICENNRYGMGT 231
Score = 31.9 bits (69), Expect = 3.2
Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 2/41 (4%)
Frame = +3
Query: 690 EFPNNDRCVICYFGDGAASEGDAHAAFNFAA--TLDCPVIC 806
++ D + +GDGAA++G A+N AA L C IC
Sbjct: 182 KYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFIC 222
>J03503-1|AAA60055.1| 414|Homo sapiens PDHA1 protein.
Length = 414
Score = 44.4 bits (100), Expect = 6e-04
Identities = 32/139 (23%), Positives = 56/139 (40%)
Frame = +2
Query: 422 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 601
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 120 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 179
Query: 602 GSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPE*RPXXXXXXXXXXXXXXXXXXXFQLCR 781
+K N + +G Q+P G A A K + + +
Sbjct: 180 YAK--NFYGGNGIVGAQVPLGAGIALACKYNGK-DEVCLTLYGDGAANQGQIFEAYNMAA 236
Query: 782 YVRLSCYMLCRNNGYAIST 838
+L C +C NN Y + T
Sbjct: 237 LWKLPCIFICENNRYGMGT 255
Score = 31.9 bits (69), Expect = 3.2
Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 2/41 (4%)
Frame = +3
Query: 690 EFPNNDRCVICYFGDGAASEGDAHAAFNFAA--TLDCPVIC 806
++ D + +GDGAA++G A+N AA L C IC
Sbjct: 206 KYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFIC 246
>EF590117-1|ABQ59099.1| 428|Homo sapiens mitochondrial PDHA1
protein.
Length = 428
Score = 44.4 bits (100), Expect = 6e-04
Identities = 32/139 (23%), Positives = 56/139 (40%)
Frame = +2
Query: 422 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 601
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 134 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 193
Query: 602 GSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPE*RPXXXXXXXXXXXXXXXXXXXFQLCR 781
+K N + +G Q+P G A A K + + +
Sbjct: 194 YAK--NFYGGNGIVGAQVPLGAGIALACKYNGK-DEVCLTLYGDGAANQGQIFEAYNMAA 250
Query: 782 YVRLSCYMLCRNNGYAIST 838
+L C +C NN Y + T
Sbjct: 251 LWKLPCIFICENNRYGMGT 269
Score = 31.9 bits (69), Expect = 3.2
Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 2/41 (4%)
Frame = +3
Query: 690 EFPNNDRCVICYFGDGAASEGDAHAAFNFAA--TLDCPVIC 806
++ D + +GDGAA++G A+N AA L C IC
Sbjct: 220 KYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFIC 260
>D90084-1|BAA14121.1| 390|Homo sapiens pyruvate dehydrogenase alpha
subunit protein.
Length = 390
Score = 44.4 bits (100), Expect = 6e-04
Identities = 32/139 (23%), Positives = 56/139 (40%)
Frame = +2
Query: 422 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 601
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 602 GSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPE*RPXXXXXXXXXXXXXXXXXXXFQLCR 781
+K N + +G Q+P G A A K + + +
Sbjct: 156 YAK--NFYGGNGIVGAQVPLGAGIALACKYNGK-DEVCLTLYGDGAANQGQIFEAYNMAA 212
Query: 782 YVRLSCYMLCRNNGYAIST 838
+L C +C NN Y + T
Sbjct: 213 LWKLPCIFICENNRYGMGT 231
Score = 31.9 bits (69), Expect = 3.2
Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 2/41 (4%)
Frame = +3
Query: 690 EFPNNDRCVICYFGDGAASEGDAHAAFNFAA--TLDCPVIC 806
++ D + +GDGAA++G A+N AA L C IC
Sbjct: 182 KYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFIC 222
>BC002406-1|AAH02406.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 390
Score = 44.4 bits (100), Expect = 6e-04
Identities = 32/139 (23%), Positives = 56/139 (40%)
Frame = +2
Query: 422 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 601
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 602 GSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPE*RPXXXXXXXXXXXXXXXXXXXFQLCR 781
+K N + +G Q+P G A A K + + +
Sbjct: 156 YAK--NFYGGNGIVGAQVPLGAGIALACKYNGK-DEVCLTLYGDGAANQGQIFEAYNMAA 212
Query: 782 YVRLSCYMLCRNNGYAIST 838
+L C +C NN Y + T
Sbjct: 213 LWKLPCIFICENNRYGMGT 231
Score = 31.9 bits (69), Expect = 3.2
Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 2/41 (4%)
Frame = +3
Query: 690 EFPNNDRCVICYFGDGAASEGDAHAAFNFAA--TLDCPVIC 806
++ D + +GDGAA++G A+N AA L C IC
Sbjct: 182 KYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFIC 222
>AL732326-7|CAI41291.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 390
Score = 44.4 bits (100), Expect = 6e-04
Identities = 32/139 (23%), Positives = 56/139 (40%)
Frame = +2
Query: 422 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 601
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 602 GSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPE*RPXXXXXXXXXXXXXXXXXXXFQLCR 781
+K N + +G Q+P G A A K + + +
Sbjct: 156 YAK--NFYGGNGIVGAQVPLGAGIALACKYNGK-DEVCLTLYGDGAANQGQIFEAYNMAA 212
Query: 782 YVRLSCYMLCRNNGYAIST 838
+L C +C NN Y + T
Sbjct: 213 LWKLPCIFICENNRYGMGT 231
Score = 31.9 bits (69), Expect = 3.2
Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 2/41 (4%)
Frame = +3
Query: 690 EFPNNDRCVICYFGDGAASEGDAHAAFNFAA--TLDCPVIC 806
++ D + +GDGAA++G A+N AA L C IC
Sbjct: 182 KYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFIC 222
>AK222988-1|BAD96708.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 variant protein.
Length = 390
Score = 44.4 bits (100), Expect = 6e-04
Identities = 32/139 (23%), Positives = 56/139 (40%)
Frame = +2
Query: 422 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 601
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 602 GSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPE*RPXXXXXXXXXXXXXXXXXXXFQLCR 781
+K N + +G Q+P G A A K + + +
Sbjct: 156 YAK--NFYGGNGIVGAQVPLGAGIALACKYNGK-DEVCLTLYGDGAANQGQIFEAYNMAA 212
Query: 782 YVRLSCYMLCRNNGYAIST 838
+L C +C NN Y + T
Sbjct: 213 LWKLPCIFICENNRYGMGT 231
Score = 31.9 bits (69), Expect = 3.2
Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 2/41 (4%)
Frame = +3
Query: 690 EFPNNDRCVICYFGDGAASEGDAHAAFNFAA--TLDCPVIC 806
++ D + +GDGAA++G A+N AA L C IC
Sbjct: 182 KYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFIC 222
>AK222740-1|BAD96460.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 variant protein.
Length = 390
Score = 44.4 bits (100), Expect = 6e-04
Identities = 32/139 (23%), Positives = 56/139 (40%)
Frame = +2
Query: 422 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 601
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 602 GSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPE*RPXXXXXXXXXXXXXXXXXXXFQLCR 781
+K N + +G Q+P G A A K + + +
Sbjct: 156 YAK--NFYGGNGIVGAQVPLGAGIALACKYNGK-DEVCLTLYGDGAANQGQIFEAYNMAA 212
Query: 782 YVRLSCYMLCRNNGYAIST 838
+L C +C NN Y + T
Sbjct: 213 LWKLPCIFICENNRYGMGT 231
Score = 31.9 bits (69), Expect = 3.2
Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 2/41 (4%)
Frame = +3
Query: 690 EFPNNDRCVICYFGDGAASEGDAHAAFNFAA--TLDCPVIC 806
++ D + +GDGAA++G A+N AA L C IC
Sbjct: 182 KYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFIC 222
>L48690-1|AAB59581.1| 390|Homo sapiens pyruvate dehydrogenase
E1-alpha subunit precursor protein.
Length = 390
Score = 43.2 bits (97), Expect = 0.001
Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Frame = +3
Query: 567 IRGKGDRCRSITEASTTTWSQYLVH*EHKCPRLLEPLMPTKEFPNNDRCVICYFGDGAAS 746
++GK DRC + ST + + E +CP + K ++ C+ Y GDGAA+
Sbjct: 146 LKGKEDRCTCMPRTSTGAMASW----ERRCPWAAGIALACKYNGKDEVCLTLY-GDGAAN 200
Query: 747 EGDAHAAFNFAA--TLDCPVIC 806
+G A+N AA L C IC
Sbjct: 201 QGQIFEAYNMAALWKLPCIFIC 222
>AL732326-6|CAI41290.1| 204|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 204
Score = 38.7 bits (86), Expect = 0.028
Identities = 24/88 (27%), Positives = 42/88 (47%)
Frame = +2
Query: 425 EEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHYG 604
+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 104 QEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMY 163
Query: 605 SKHHNMVTISSPLGTQMPQAVGAAYAYK 688
+K N + +G Q+P G A A K
Sbjct: 164 AK--NFYGGNGIVGAQVPLGAGIALACK 189
>AL732326-5|CAI41289.1| 180|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 180
Score = 34.7 bits (76), Expect = 0.45
Identities = 17/64 (26%), Positives = 33/64 (51%)
Frame = +2
Query: 422 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 601
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 602 GSKH 613
+K+
Sbjct: 156 YAKN 159
>AL732326-4|CAI41288.1| 205|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 205
Score = 34.7 bits (76), Expect = 0.45
Identities = 17/64 (26%), Positives = 33/64 (51%)
Frame = +2
Query: 422 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 601
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 134 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 193
Query: 602 GSKH 613
+K+
Sbjct: 194 YAKN 197
>CR541928-1|CAG46726.1| 274|Homo sapiens CCS protein.
Length = 274
Score = 32.3 bits (70), Expect = 2.4
Identities = 24/67 (35%), Positives = 30/67 (44%), Gaps = 5/67 (7%)
Frame = +1
Query: 412 DQLRRGGHPHRQRLGTLTERFGLQSIQRSRSVF-IPRD--DCDGTC--EPVLRKLRGSGE 576
D L RGGHP + G ER I RS +F P+ CDG E R + G G
Sbjct: 205 DDLGRGGHPLSKITGNSGERLACGIIARSAGLFQNPKQICSCDGLTIWEERGRPIAGKGR 264
Query: 577 RETDAGP 597
+E+ P
Sbjct: 265 KESAQPP 271
>BC112055-1|AAI12056.1| 274|Homo sapiens copper chaperone for
superoxide dismutase protein.
Length = 274
Score = 32.3 bits (70), Expect = 2.4
Identities = 24/67 (35%), Positives = 30/67 (44%), Gaps = 5/67 (7%)
Frame = +1
Query: 412 DQLRRGGHPHRQRLGTLTERFGLQSIQRSRSVF-IPRD--DCDGTC--EPVLRKLRGSGE 576
D L RGGHP + G ER I RS +F P+ CDG E R + G G
Sbjct: 205 DDLGRGGHPLSKITGNSGERLACGIIARSAGLFQNPKQICSCDGLTIWEERGRPIAGKGR 264
Query: 577 RETDAGP 597
+E+ P
Sbjct: 265 KESAQPP 271
>BC105016-1|AAI05017.1| 274|Homo sapiens copper chaperone for
superoxide dismutase protein.
Length = 274
Score = 32.3 bits (70), Expect = 2.4
Identities = 24/67 (35%), Positives = 30/67 (44%), Gaps = 5/67 (7%)
Frame = +1
Query: 412 DQLRRGGHPHRQRLGTLTERFGLQSIQRSRSVF-IPRD--DCDGTC--EPVLRKLRGSGE 576
D L RGGHP + G ER I RS +F P+ CDG E R + G G
Sbjct: 205 DDLGRGGHPLSKITGNSGERLACGIIARSAGLFQNPKQICSCDGLTIWEERGRPIAGKGR 264
Query: 577 RETDAGP 597
+E+ P
Sbjct: 265 KESAQPP 271
>AY113179-1|AAM50090.1| 274|Homo sapiens superoxide dismutase
copper chaperone protein.
Length = 274
Score = 32.3 bits (70), Expect = 2.4
Identities = 24/67 (35%), Positives = 30/67 (44%), Gaps = 5/67 (7%)
Frame = +1
Query: 412 DQLRRGGHPHRQRLGTLTERFGLQSIQRSRSVF-IPRD--DCDGTC--EPVLRKLRGSGE 576
D L RGGHP + G ER I RS +F P+ CDG E R + G G
Sbjct: 205 DDLGRGGHPLSKITGNSGERLACGIIARSAGLFQNPKQICSCDGLTIWEERGRPIAGKGR 264
Query: 577 RETDAGP 597
+E+ P
Sbjct: 265 KESAQPP 271
>AF002210-1|AAC51764.1| 274|Homo sapiens copper chaperone for
superoxide dismutase protein.
Length = 274
Score = 32.3 bits (70), Expect = 2.4
Identities = 24/67 (35%), Positives = 30/67 (44%), Gaps = 5/67 (7%)
Frame = +1
Query: 412 DQLRRGGHPHRQRLGTLTERFGLQSIQRSRSVF-IPRD--DCDGTC--EPVLRKLRGSGE 576
D L RGGHP + G ER I RS +F P+ CDG E R + G G
Sbjct: 205 DDLGRGGHPLSKITGNSGERLACGIIARSAGLFQNPKQICSCDGLTIWEERGRPIAGKGR 264
Query: 577 RETDAGP 597
+E+ P
Sbjct: 265 KESAQPP 271
>EF576990-1|ABQ58815.1| 261|Homo sapiens PDHA1 protein.
Length = 261
Score = 31.9 bits (69), Expect = 3.2
Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 2/41 (4%)
Frame = +3
Query: 690 EFPNNDRCVICYFGDGAASEGDAHAAFNFAA--TLDCPVIC 806
++ D + +GDGAA++G A+N AA L C IC
Sbjct: 53 KYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFIC 93
>AM746210-1|CAN88919.1| 302|Homo sapiens PDHA1/LOC79064 protein
protein.
Length = 302
Score = 31.9 bits (69), Expect = 3.2
Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 2/41 (4%)
Frame = +3
Query: 690 EFPNNDRCVICYFGDGAASEGDAHAAFNFAA--TLDCPVIC 806
++ D + +GDGAA++G A+N AA L C IC
Sbjct: 94 KYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFIC 134
>L23808-1|AAA58658.1| 470|Homo sapiens metalloproteinase protein.
Length = 470
Score = 30.3 bits (65), Expect = 9.7
Identities = 18/82 (21%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Frame = +2
Query: 353 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 532
+H D+ + + G + ++T E G +G + PK ++F Y+ V + +R ++
Sbjct: 195 AHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFR-LSAD 253
Query: 533 EL--VNQCYGNCEDPGKGRQMP 592
++ + YG DP + +++P
Sbjct: 254 DIRGIQSLYG---DPKENQRLP 272
>BC112301-1|AAI12302.1| 470|Homo sapiens matrix metalloproteinase
12, preproprotein protein.
Length = 470
Score = 30.3 bits (65), Expect = 9.7
Identities = 18/82 (21%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Frame = +2
Query: 353 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 532
+H D+ + + G + ++T E G +G + PK ++F Y+ V + +R ++
Sbjct: 195 AHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFR-LSAD 253
Query: 533 EL--VNQCYGNCEDPGKGRQMP 592
++ + YG DP + +++P
Sbjct: 254 DIRGIQSLYG---DPKENQRLP 272
>AY856072-1|AAW29944.1| 470|Homo sapiens matrix metalloproteinase
12 (macrophage elastase) protein.
Length = 470
Score = 30.3 bits (65), Expect = 9.7
Identities = 18/82 (21%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Frame = +2
Query: 353 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 532
+H D+ + + G + ++T E G +G + PK ++F Y+ V + +R ++
Sbjct: 195 AHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFR-LSAD 253
Query: 533 EL--VNQCYGNCEDPGKGRQMP 592
++ + YG DP + +++P
Sbjct: 254 DIRGIQSLYG---DPKENQRLP 272
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 125,526,614
Number of Sequences: 237096
Number of extensions: 2690140
Number of successful extensions: 9752
Number of sequences better than 10.0: 45
Number of HSP's better than 10.0 without gapping: 9425
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 9732
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11270645666
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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