Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP21_F_J23
(910 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein. 179 1e-44
M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein. 179 1e-44
M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein. 179 1e-44
CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein. 179 1e-44
BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal ... 179 1e-44
BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal ... 179 1e-44
BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein. 179 1e-44
BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic pepti... 159 2e-38
AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4 pro... 158 2e-38
AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor prot... 158 2e-38
AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein. 158 2e-38
BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein. 140 6e-33
AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3 pro... 140 6e-33
M26901-1|AAA60364.1| 403|Homo sapiens renin protein. 137 4e-32
M10152-1|AAD03461.1| 406|Homo sapiens renin protein. 137 4e-32
L00073-1|AAA60363.1| 406|Homo sapiens renin protein. 137 4e-32
CR536498-1|CAG38737.1| 406|Homo sapiens REN protein. 137 4e-32
BC047752-1|AAH47752.1| 406|Homo sapiens renin protein. 137 4e-32
BC033474-1|AAH33474.1| 406|Homo sapiens renin protein. 137 4e-32
AY436324-1|AAR03502.1| 403|Homo sapiens renin protein. 137 4e-32
AL592146-1|CAI16594.1| 406|Homo sapiens renin protein. 137 4e-32
AL592114-1|CAH71224.1| 406|Homo sapiens renin protein. 137 4e-32
M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein. 134 6e-31
J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein. 134 6e-31
BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein. 134 6e-31
BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein. 134 6e-31
BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein. 134 6e-31
AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein. 134 6e-31
AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternativ... 134 6e-31
U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein. 133 7e-31
M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein. 133 7e-31
M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein. 133 7e-31
J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein. 133 7e-31
BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinog... 133 7e-31
AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinog... 133 7e-31
J00287-1|AAA98529.1| 388|Homo sapiens PEP protein. 130 5e-30
BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I (... 130 5e-30
M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein. 129 2e-29
X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mR... 84 8e-16
BC042578-1|AAH42578.1| 104|Homo sapiens PGC protein protein. 60 1e-08
BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving ... 53 1e-06
AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein. 53 1e-06
AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein. 53 1e-06
AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic ... 53 1e-06
AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1 pro... 53 1e-06
AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein. 53 1e-06
AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein. 53 1e-06
AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein. 53 1e-06
AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein. 53 1e-06
AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease ... 53 1e-06
AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein. 53 1e-06
AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens ... 50 9e-06
DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving ... 44 0.001
BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving ... 44 0.001
AF338816-1|AAK38374.1| 476|Homo sapiens beta-site APP cleaving ... 44 0.001
AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic ... 44 0.001
AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase prot... 44 0.001
AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2 pro... 44 0.001
AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein. 44 0.001
AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving ... 44 0.001
AB050436-1|BAB40931.1| 476|Homo sapiens beta-site APP cleaving ... 44 0.001
AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein. 44 0.001
AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving ... 42 0.003
AB050438-1|BAB40933.1| 432|Homo sapiens beta-site APP cleaving ... 42 0.003
AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving ... 42 0.003
BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving ... 41 0.005
AL365205-3|CAM16152.1| 86|Homo sapiens progastricsin (pepsinog... 39 0.029
AL163285-1|CAB90554.1| 415|Homo sapiens beta-site APP-cleaving ... 37 0.12
AB089958-1|BAC81826.1| 127|Homo sapiens beta-site APP cleaving ... 37 0.12
BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain cont... 31 7.6
BC035605-1|AAH35605.1| 578|Homo sapiens schlafen family member ... 25 9.5
AK001122-1|BAA91512.1| 578|Homo sapiens protein ( Homo sapiens ... 25 9.5
>X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 179 bits (436), Expect = 1e-44
Identities = 100/192 (52%), Positives = 116/192 (60%), Gaps = 22/192 (11%)
Frame = +2
Query: 203 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 349
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 350 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 529
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 530 YVANGTXFAIQYGSGXLSGFLSTDDVTV-----------GGLKVRRXXFXXAVSXPGLAF 676
YV NGT F I YGSG LSG+LS D V+V GG+KV R F A PG+ F
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITF 190
Query: 677 XAAXFXGIPGMA 712
AA F GI GMA
Sbjct: 191 IAAKFDGILGMA 202
>M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 179 bits (436), Expect = 1e-44
Identities = 100/192 (52%), Positives = 116/192 (60%), Gaps = 22/192 (11%)
Frame = +2
Query: 203 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 349
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 350 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 529
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 530 YVANGTXFAIQYGSGXLSGFLSTDDVTV-----------GGLKVRRXXFXXAVSXPGLAF 676
YV NGT F I YGSG LSG+LS D V+V GG+KV R F A PG+ F
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITF 190
Query: 677 XAAXFXGIPGMA 712
AA F GI GMA
Sbjct: 191 IAAKFDGILGMA 202
>M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 179 bits (436), Expect = 1e-44
Identities = 100/192 (52%), Positives = 116/192 (60%), Gaps = 22/192 (11%)
Frame = +2
Query: 203 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 349
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 350 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 529
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 530 YVANGTXFAIQYGSGXLSGFLSTDDVTV-----------GGLKVRRXXFXXAVSXPGLAF 676
YV NGT F I YGSG LSG+LS D V+V GG+KV R F A PG+ F
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITF 190
Query: 677 XAAXFXGIPGMA 712
AA F GI GMA
Sbjct: 191 IAAKFDGILGMA 202
>CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 179 bits (436), Expect = 1e-44
Identities = 100/192 (52%), Positives = 116/192 (60%), Gaps = 22/192 (11%)
Frame = +2
Query: 203 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 349
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 350 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 529
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 530 YVANGTXFAIQYGSGXLSGFLSTDDVTV-----------GGLKVRRXXFXXAVSXPGLAF 676
YV NGT F I YGSG LSG+LS D V+V GG+KV R F A PG+ F
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITF 190
Query: 677 XAAXFXGIPGMA 712
AA F GI GMA
Sbjct: 191 IAAKFDGILGMA 202
>BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 179 bits (436), Expect = 1e-44
Identities = 100/192 (52%), Positives = 116/192 (60%), Gaps = 22/192 (11%)
Frame = +2
Query: 203 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 349
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 350 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 529
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 530 YVANGTXFAIQYGSGXLSGFLSTDDVTV-----------GGLKVRRXXFXXAVSXPGLAF 676
YV NGT F I YGSG LSG+LS D V+V GG+KV R F A PG+ F
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITF 190
Query: 677 XAAXFXGIPGMA 712
AA F GI GMA
Sbjct: 191 IAAKFDGILGMA 202
>BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 179 bits (436), Expect = 1e-44
Identities = 100/192 (52%), Positives = 116/192 (60%), Gaps = 22/192 (11%)
Frame = +2
Query: 203 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 349
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 350 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 529
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 530 YVANGTXFAIQYGSGXLSGFLSTDDVTV-----------GGLKVRRXXFXXAVSXPGLAF 676
YV NGT F I YGSG LSG+LS D V+V GG+KV R F A PG+ F
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITF 190
Query: 677 XAAXFXGIPGMA 712
AA F GI GMA
Sbjct: 191 IAAKFDGILGMA 202
>BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 179 bits (436), Expect = 1e-44
Identities = 100/192 (52%), Positives = 116/192 (60%), Gaps = 22/192 (11%)
Frame = +2
Query: 203 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 349
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 350 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 529
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 530 YVANGTXFAIQYGSGXLSGFLSTDDVTV-----------GGLKVRRXXFXXAVSXPGLAF 676
YV NGT F I YGSG LSG+LS D V+V GG+KV R F A PG+ F
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITF 190
Query: 677 XAAXFXGIPGMA 712
AA F GI GMA
Sbjct: 191 IAAKFDGILGMA 202
>BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic
peptidase protein.
Length = 420
Score = 159 bits (385), Expect = 2e-38
Identities = 78/171 (45%), Positives = 106/171 (61%), Gaps = 5/171 (2%)
Frame = +2
Query: 212 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 376
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRTLNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 377 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXFA 556
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S ++ ANGT FA
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFA 138
Query: 557 IQYGSGXLSGFLSTDDVTVGGLKVRRXXFXXAVSXPGLAFXAAXFXGIPGM 709
IQYG+G + G LS D +T+GG+K F A+ P L F A F GI G+
Sbjct: 139 IQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAHFDGILGL 189
>AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4
protein.
Length = 420
Score = 158 bits (384), Expect = 2e-38
Identities = 78/171 (45%), Positives = 106/171 (61%), Gaps = 5/171 (2%)
Frame = +2
Query: 212 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 376
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 377 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXFA 556
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S ++ ANGT FA
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFA 138
Query: 557 IQYGSGXLSGFLSTDDVTVGGLKVRRXXFXXAVSXPGLAFXAAXFXGIPGM 709
IQYG+G + G LS D +T+GG+K F A+ P L F A F GI G+
Sbjct: 139 IQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAHFDGILGL 189
>AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor
protein.
Length = 420
Score = 158 bits (384), Expect = 2e-38
Identities = 78/171 (45%), Positives = 106/171 (61%), Gaps = 5/171 (2%)
Frame = +2
Query: 212 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 376
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 377 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXFA 556
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S ++ ANGT FA
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFA 138
Query: 557 IQYGSGXLSGFLSTDDVTVGGLKVRRXXFXXAVSXPGLAFXAAXFXGIPGM 709
IQYG+G + G LS D +T+GG+K F A+ P L F A F GI G+
Sbjct: 139 IQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAHFDGILGL 189
>AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein.
Length = 420
Score = 158 bits (384), Expect = 2e-38
Identities = 78/171 (45%), Positives = 106/171 (61%), Gaps = 5/171 (2%)
Frame = +2
Query: 212 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 376
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 377 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXFA 556
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S ++ ANGT FA
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFA 138
Query: 557 IQYGSGXLSGFLSTDDVTVGGLKVRRXXFXXAVSXPGLAFXAAXFXGIPGM 709
IQYG+G + G LS D +T+GG+K F A+ P L F A F GI G+
Sbjct: 139 IQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAHFDGILGL 189
>BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein.
Length = 464
Score = 140 bits (339), Expect = 6e-33
Identities = 69/164 (42%), Positives = 99/164 (60%), Gaps = 5/164 (3%)
Frame = +2
Query: 233 LYRVPLHRMKTARTHFHEV---GTELELLRLKYDVTGPSPE--PLSNYLDAQYYGVISIG 397
L R+PL ++ R + + G EL +L G P PLS +LDAQY+G I +G
Sbjct: 22 LIRIPLRQVHPGRRTLNLLRGWGKPAELPKLGAPSPGDKPASVPLSKFLDAQYFGEIGLG 81
Query: 398 TPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXFAIQYGSGX 577
TPPQ+F V FDTGSSNLWVPS++CH+ ++ C H++++ S ++ +GT FAIQYG+G
Sbjct: 82 TPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWFHHRFNPNASSSFKPSGTKFAIQYGTGR 141
Query: 578 LSGFLSTDDVTVGGLKVRRXXFXXAVSXPGLAFXAAXFXGIPGM 709
+ G LS D +T+GG+K F A+ L F + GI G+
Sbjct: 142 VDGILSEDKLTIGGIKGASVIFGEALWESSLVFTVSRPDGILGL 185
>AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3
protein.
Length = 450
Score = 140 bits (339), Expect = 6e-33
Identities = 69/164 (42%), Positives = 99/164 (60%), Gaps = 5/164 (3%)
Frame = +2
Query: 233 LYRVPLHRMKTARTHFHEV---GTELELLRLKYDVTGPSPE--PLSNYLDAQYYGVISIG 397
L R+PL ++ R + + G EL +L G P PLS +LDAQY+G I +G
Sbjct: 26 LIRIPLRQVHPGRRTLNLLRGWGKPAELPKLGAPSPGDKPASVPLSKFLDAQYFGEIGLG 85
Query: 398 TPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXFAIQYGSGX 577
TPPQ+F V FDTGSSNLWVPS++CH+ ++ C H++++ S ++ +GT FAIQYG+G
Sbjct: 86 TPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWFHHRFNPNASSSFKPSGTKFAIQYGTGR 145
Query: 578 LSGFLSTDDVTVGGLKVRRXXFXXAVSXPGLAFXAAXFXGIPGM 709
+ G LS D +T+GG+K F A+ L F + GI G+
Sbjct: 146 VDGILSEDKLTIGGIKGASVIFGEALWESSLVFTVSRPDGILGL 189
>M26901-1|AAA60364.1| 403|Homo sapiens renin protein.
Length = 403
Score = 137 bits (332), Expect = 4e-32
Identities = 63/120 (52%), Positives = 79/120 (65%)
Frame = +2
Query: 350 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 529
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 530 YVANGTXFAIQYGSGXLSGFLSTDDVTVGGLKVRRXXFXXAVSXPGLAFXAAXFXGIPGM 709
Y NGT ++Y +G +SGFLS D +TVGG+ V + F P L F A F G+ GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQ-MFGEVTEMPALPFMLAQFDGVVGM 196
>M10152-1|AAD03461.1| 406|Homo sapiens renin protein.
Length = 406
Score = 137 bits (332), Expect = 4e-32
Identities = 63/120 (52%), Positives = 79/120 (65%)
Frame = +2
Query: 350 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 529
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 530 YVANGTXFAIQYGSGXLSGFLSTDDVTVGGLKVRRXXFXXAVSXPGLAFXAAXFXGIPGM 709
Y NGT ++Y +G +SGFLS D +TVGG+ V + F P L F A F G+ GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQ-MFGEVTEMPALPFMLAEFDGVVGM 196
>L00073-1|AAA60363.1| 406|Homo sapiens renin protein.
Length = 406
Score = 137 bits (332), Expect = 4e-32
Identities = 63/120 (52%), Positives = 79/120 (65%)
Frame = +2
Query: 350 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 529
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 530 YVANGTXFAIQYGSGXLSGFLSTDDVTVGGLKVRRXXFXXAVSXPGLAFXAAXFXGIPGM 709
Y NGT ++Y +G +SGFLS D +TVGG+ V + F P L F A F G+ GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQ-MFGEVTEMPALPFMLAEFDGVVGM 196
>CR536498-1|CAG38737.1| 406|Homo sapiens REN protein.
Length = 406
Score = 137 bits (332), Expect = 4e-32
Identities = 63/120 (52%), Positives = 79/120 (65%)
Frame = +2
Query: 350 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 529
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 530 YVANGTXFAIQYGSGXLSGFLSTDDVTVGGLKVRRXXFXXAVSXPGLAFXAAXFXGIPGM 709
Y NGT ++Y +G +SGFLS D +TVGG+ V + F P L F A F G+ GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQ-MFGEVTEMPALPFMLAEFDGVVGM 196
>BC047752-1|AAH47752.1| 406|Homo sapiens renin protein.
Length = 406
Score = 137 bits (332), Expect = 4e-32
Identities = 63/120 (52%), Positives = 79/120 (65%)
Frame = +2
Query: 350 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 529
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 530 YVANGTXFAIQYGSGXLSGFLSTDDVTVGGLKVRRXXFXXAVSXPGLAFXAAXFXGIPGM 709
Y NGT ++Y +G +SGFLS D +TVGG+ V + F P L F A F G+ GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQ-MFGEVTEMPALPFMLAEFDGVVGM 196
>BC033474-1|AAH33474.1| 406|Homo sapiens renin protein.
Length = 406
Score = 137 bits (332), Expect = 4e-32
Identities = 63/120 (52%), Positives = 79/120 (65%)
Frame = +2
Query: 350 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 529
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 530 YVANGTXFAIQYGSGXLSGFLSTDDVTVGGLKVRRXXFXXAVSXPGLAFXAAXFXGIPGM 709
Y NGT ++Y +G +SGFLS D +TVGG+ V + F P L F A F G+ GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQ-MFGEVTEMPALPFMLAEFDGVVGM 196
>AY436324-1|AAR03502.1| 403|Homo sapiens renin protein.
Length = 403
Score = 137 bits (332), Expect = 4e-32
Identities = 63/120 (52%), Positives = 79/120 (65%)
Frame = +2
Query: 350 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 529
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 530 YVANGTXFAIQYGSGXLSGFLSTDDVTVGGLKVRRXXFXXAVSXPGLAFXAAXFXGIPGM 709
Y NGT ++Y +G +SGFLS D +TVGG+ V + F P L F A F G+ GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQ-MFGEVTEMPALPFMLAEFDGVVGM 196
>AL592146-1|CAI16594.1| 406|Homo sapiens renin protein.
Length = 406
Score = 137 bits (332), Expect = 4e-32
Identities = 63/120 (52%), Positives = 79/120 (65%)
Frame = +2
Query: 350 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 529
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 530 YVANGTXFAIQYGSGXLSGFLSTDDVTVGGLKVRRXXFXXAVSXPGLAFXAAXFXGIPGM 709
Y NGT ++Y +G +SGFLS D +TVGG+ V + F P L F A F G+ GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQ-MFGEVTEMPALPFMLAEFDGVVGM 196
>AL592114-1|CAH71224.1| 406|Homo sapiens renin protein.
Length = 406
Score = 137 bits (332), Expect = 4e-32
Identities = 63/120 (52%), Positives = 79/120 (65%)
Frame = +2
Query: 350 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 529
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 530 YVANGTXFAIQYGSGXLSGFLSTDDVTVGGLKVRRXXFXXAVSXPGLAFXAAXFXGIPGM 709
Y NGT ++Y +G +SGFLS D +TVGG+ V + F P L F A F G+ GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQ-MFGEVTEMPALPFMLAEFDGVVGM 196
>M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 134 bits (323), Expect = 6e-31
Identities = 76/182 (41%), Positives = 104/182 (57%), Gaps = 10/182 (5%)
Frame = +2
Query: 194 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 343
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 344 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 523
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 524 KTYVANGTXFAIQYGSGXLSGFLSTDDVTVGGLKVRRXXFXXAVSXPGLAFXAAXFXGIP 703
TY G F+IQYG+G LSG + D V+V GL V F +V+ PG F A F GI
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGIL 185
Query: 704 GM 709
G+
Sbjct: 186 GL 187
>J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein.
Length = 396
Score = 134 bits (323), Expect = 6e-31
Identities = 76/182 (41%), Positives = 104/182 (57%), Gaps = 10/182 (5%)
Frame = +2
Query: 194 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 343
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 344 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 523
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 524 KTYVANGTXFAIQYGSGXLSGFLSTDDVTVGGLKVRRXXFXXAVSXPGLAFXAAXFXGIP 703
TY G F+IQYG+G LSG + D V+V GL V F +V+ PG F A F GI
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGIL 185
Query: 704 GM 709
G+
Sbjct: 186 GL 187
>BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein.
Length = 363
Score = 134 bits (323), Expect = 6e-31
Identities = 76/182 (41%), Positives = 104/182 (57%), Gaps = 10/182 (5%)
Frame = +2
Query: 194 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 343
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 344 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 523
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 524 KTYVANGTXFAIQYGSGXLSGFLSTDDVTVGGLKVRRXXFXXAVSXPGLAFXAAXFXGIP 703
TY G F+IQYG+G LSG + D V+V GL V F +V+ PG F A F GI
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGIL 185
Query: 704 GM 709
G+
Sbjct: 186 GL 187
>BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 134 bits (323), Expect = 6e-31
Identities = 76/182 (41%), Positives = 104/182 (57%), Gaps = 10/182 (5%)
Frame = +2
Query: 194 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 343
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 344 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 523
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 524 KTYVANGTXFAIQYGSGXLSGFLSTDDVTVGGLKVRRXXFXXAVSXPGLAFXAAXFXGIP 703
TY G F+IQYG+G LSG + D V+V GL V F +V+ PG F A F GI
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGIL 185
Query: 704 GM 709
G+
Sbjct: 186 GL 187
>BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 134 bits (323), Expect = 6e-31
Identities = 76/182 (41%), Positives = 104/182 (57%), Gaps = 10/182 (5%)
Frame = +2
Query: 194 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 343
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 344 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 523
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 524 KTYVANGTXFAIQYGSGXLSGFLSTDDVTVGGLKVRRXXFXXAVSXPGLAFXAAXFXGIP 703
TY G F+IQYG+G LSG + D V+V GL V F +V+ PG F A F GI
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGIL 185
Query: 704 GM 709
G+
Sbjct: 186 GL 187
>AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein.
Length = 396
Score = 134 bits (323), Expect = 6e-31
Identities = 76/182 (41%), Positives = 104/182 (57%), Gaps = 10/182 (5%)
Frame = +2
Query: 194 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 343
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 344 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 523
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 524 KTYVANGTXFAIQYGSGXLSGFLSTDDVTVGGLKVRRXXFXXAVSXPGLAFXAAXFXGIP 703
TY G F+IQYG+G LSG + D V+V GL V F +V+ PG F A F GI
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGIL 185
Query: 704 GM 709
G+
Sbjct: 186 GL 187
>AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternative
protein.
Length = 363
Score = 134 bits (323), Expect = 6e-31
Identities = 76/182 (41%), Positives = 104/182 (57%), Gaps = 10/182 (5%)
Frame = +2
Query: 194 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 343
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 344 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 523
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 524 KTYVANGTXFAIQYGSGXLSGFLSTDDVTVGGLKVRRXXFXXAVSXPGLAFXAAXFXGIP 703
TY G F+IQYG+G LSG + D V+V GL V F +V+ PG F A F GI
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGIL 185
Query: 704 GM 709
G+
Sbjct: 186 GL 187
>U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein.
Length = 388
Score = 133 bits (322), Expect = 7e-31
Identities = 75/170 (44%), Positives = 101/170 (59%), Gaps = 9/170 (5%)
Frame = +2
Query: 230 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 382
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 383 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXFAIQ 562
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 563 YGSGXLSGFLSTDDVTVGGLKVRRXXFXXAVSXPGLAFXAAXFXGIPGMA 712
YGSG L+GF D +TV ++V F + + PG F A F GI G+A
Sbjct: 134 YGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLA 183
>M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein.
Length = 388
Score = 133 bits (322), Expect = 7e-31
Identities = 75/170 (44%), Positives = 101/170 (59%), Gaps = 9/170 (5%)
Frame = +2
Query: 230 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 382
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 383 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXFAIQ 562
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 563 YGSGXLSGFLSTDDVTVGGLKVRRXXFXXAVSXPGLAFXAAXFXGIPGMA 712
YGSG L+GF D +TV ++V F + + PG F A F GI G+A
Sbjct: 134 YGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLA 183
>M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein.
Length = 385
Score = 133 bits (322), Expect = 7e-31
Identities = 75/170 (44%), Positives = 101/170 (59%), Gaps = 9/170 (5%)
Frame = +2
Query: 230 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 382
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 14 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 72
Query: 383 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXFAIQ 562
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 73 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 130
Query: 563 YGSGXLSGFLSTDDVTVGGLKVRRXXFXXAVSXPGLAFXAAXFXGIPGMA 712
YGSG L+GF D +TV ++V F + + PG F A F GI G+A
Sbjct: 131 YGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLA 180
>J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein.
Length = 388
Score = 133 bits (322), Expect = 7e-31
Identities = 75/170 (44%), Positives = 101/170 (59%), Gaps = 9/170 (5%)
Frame = +2
Query: 230 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 382
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 383 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXFAIQ 562
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 563 YGSGXLSGFLSTDDVTVGGLKVRRXXFXXAVSXPGLAFXAAXFXGIPGMA 712
YGSG L+GF D +TV ++V F + + PG F A F GI G+A
Sbjct: 134 YGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLA 183
>BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 133 bits (322), Expect = 7e-31
Identities = 75/170 (44%), Positives = 101/170 (59%), Gaps = 9/170 (5%)
Frame = +2
Query: 230 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 382
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 383 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXFAIQ 562
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 563 YGSGXLSGFLSTDDVTVGGLKVRRXXFXXAVSXPGLAFXAAXFXGIPGMA 712
YGSG L+GF D +TV ++V F + + PG F A F GI G+A
Sbjct: 134 YGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLA 183
>AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 133 bits (322), Expect = 7e-31
Identities = 75/170 (44%), Positives = 101/170 (59%), Gaps = 9/170 (5%)
Frame = +2
Query: 230 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 382
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 383 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXFAIQ 562
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 563 YGSGXLSGFLSTDDVTVGGLKVRRXXFXXAVSXPGLAFXAAXFXGIPGMA 712
YGSG L+GF D +TV ++V F + + PG F A F GI G+A
Sbjct: 134 YGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLA 183
>J00287-1|AAA98529.1| 388|Homo sapiens PEP protein.
Length = 388
Score = 130 bits (315), Expect = 5e-30
Identities = 75/185 (40%), Positives = 100/185 (54%), Gaps = 12/185 (6%)
Frame = +2
Query: 194 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 343
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLV 63
Query: 344 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSR 517
+PL NYLD +Y+G I IGTP Q F VVFDTGSSNLWVPS C +++AC HN+++
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYC--SSLACTNHNRFNPE 121
Query: 518 KSKTYVANGTXFAIQYGSGXLSGFLSTDDVTVGGLKVRRXXFXXAVSXPGLAFXAAXFXG 697
S TY + +I YG+G ++G L D V VGG+ F + + PG A F G
Sbjct: 122 DSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDG 181
Query: 698 IPGMA 712
I G+A
Sbjct: 182 ILGLA 186
>BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I
(pepsinogen A) protein.
Length = 388
Score = 130 bits (315), Expect = 5e-30
Identities = 75/185 (40%), Positives = 100/185 (54%), Gaps = 12/185 (6%)
Frame = +2
Query: 194 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 343
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLV 63
Query: 344 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSR 517
+PL NYLD +Y+G I IGTP Q F VVFDTGSSNLWVPS C +++AC HN+++
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYC--SSLACTNHNRFNPE 121
Query: 518 KSKTYVANGTXFAIQYGSGXLSGFLSTDDVTVGGLKVRRXXFXXAVSXPGLAFXAAXFXG 697
S TY + +I YG+G ++G L D V VGG+ F + + PG A F G
Sbjct: 122 DSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDG 181
Query: 698 IPGMA 712
I G+A
Sbjct: 182 ILGLA 186
>M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein.
Length = 388
Score = 129 bits (311), Expect = 2e-29
Identities = 74/185 (40%), Positives = 100/185 (54%), Gaps = 12/185 (6%)
Frame = +2
Query: 194 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 343
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSFRRTLSERGLLKDFLKKHNLNPARKYFPQWKAPTLV 63
Query: 344 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSR 517
+PL NYLD +Y+G I IGTP Q F V+FDTGSSNLWVPS C +++AC HN+++
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVLFDTGSSNLWVPSVYC--SSLACTNHNRFNPE 121
Query: 518 KSKTYVANGTXFAIQYGSGXLSGFLSTDDVTVGGLKVRRXXFXXAVSXPGLAFXAAXFXG 697
S TY + +I YG+G ++G L D V VGG+ F + + PG A F G
Sbjct: 122 DSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDG 181
Query: 698 IPGMA 712
I G+A
Sbjct: 182 ILGLA 186
>X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mRNA
fragment for renin (aa 105-401). ).
Length = 300
Score = 83.8 bits (198), Expect = 8e-16
Identities = 39/90 (43%), Positives = 52/90 (57%)
Frame = +2
Query: 440 SNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXFAIQYGSGXLSGFLSTDDVTVGG 619
SN+WVPS KC AC+ H +D+ S +Y NGT ++Y +G +SGFLS D +TVGG
Sbjct: 1 SNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGG 60
Query: 620 LKVRRXXFXXAVSXPGLAFXAAXFXGIPGM 709
+ V + F P L F A F G+ GM
Sbjct: 61 ITVTQ-MFGEVTEMPALPFMLAEFDGVVGM 89
>BC042578-1|AAH42578.1| 104|Homo sapiens PGC protein protein.
Length = 104
Score = 60.1 bits (139), Expect = 1e-08
Identities = 38/82 (46%), Positives = 49/82 (59%), Gaps = 9/82 (10%)
Frame = +2
Query: 230 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 382
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 383 VISIGTPPQSFKVVFDTGSSNL 448
ISIGTPPQ+F V+FDTGSS L
Sbjct: 76 EISIGTPPQNFLVLFDTGSSPL 97
>BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving
enzyme 2 protein.
Length = 518
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/80 (35%), Positives = 42/80 (52%)
Frame = +2
Query: 374 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXF 553
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 554 AIQYGSGXLSGFLSTDDVTV 613
++Y G +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein.
Length = 518
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/80 (35%), Positives = 42/80 (52%)
Frame = +2
Query: 374 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXF 553
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 554 AIQYGSGXLSGFLSTDDVTV 613
++Y G +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein.
Length = 439
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/80 (35%), Positives = 42/80 (52%)
Frame = +2
Query: 374 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXF 553
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 13 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 66
Query: 554 AIQYGSGXLSGFLSTDDVTV 613
++Y G +GF+ D VT+
Sbjct: 67 TVKYTQGSWTGFVGEDLVTI 86
>AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic
proteinase Asp 1 protein.
Length = 518
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/80 (35%), Positives = 42/80 (52%)
Frame = +2
Query: 374 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXF 553
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 554 AIQYGSGXLSGFLSTDDVTV 613
++Y G +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1
protein.
Length = 518
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/80 (35%), Positives = 42/80 (52%)
Frame = +2
Query: 374 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXF 553
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 554 AIQYGSGXLSGFLSTDDVTV 613
++Y G +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein.
Length = 518
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/80 (35%), Positives = 42/80 (52%)
Frame = +2
Query: 374 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXF 553
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 554 AIQYGSGXLSGFLSTDDVTV 613
++Y G +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein.
Length = 396
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/80 (35%), Positives = 42/80 (52%)
Frame = +2
Query: 374 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXF 553
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 554 AIQYGSGXLSGFLSTDDVTV 613
++Y G +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein.
Length = 468
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/80 (35%), Positives = 42/80 (52%)
Frame = +2
Query: 374 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXF 553
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 554 AIQYGSGXLSGFLSTDDVTV 613
++Y G +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/80 (35%), Positives = 42/80 (52%)
Frame = +2
Query: 374 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXF 553
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 554 AIQYGSGXLSGFLSTDDVTV 613
++Y G +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease
protein.
Length = 518
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/80 (35%), Positives = 42/80 (52%)
Frame = +2
Query: 374 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXF 553
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 554 AIQYGSGXLSGFLSTDDVTV 613
++Y G +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/80 (35%), Positives = 42/80 (52%)
Frame = +2
Query: 374 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXF 553
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 554 AIQYGSGXLSGFLSTDDVTV 613
++Y G +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens
cDNA PSEC0239 fis, clone OVARC1000363, highly similar to
Homo sapiens aspartyl protease mRNA. ).
Length = 423
Score = 50.4 bits (115), Expect = 9e-06
Identities = 26/74 (35%), Positives = 39/74 (52%)
Frame = +2
Query: 392 IGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXFAIQYGS 571
IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G ++Y
Sbjct: 3 IGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDVTVKYTQ 56
Query: 572 GXLSGFLSTDDVTV 613
G +GF+ D VT+
Sbjct: 57 GSWTGFVGEDLVTI 70
>DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 43.6 bits (98), Expect = 0.001
Identities = 26/80 (32%), Positives = 39/80 (48%)
Frame = +2
Query: 374 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXF 553
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 554 AIQYGSGXLSGFLSTDDVTV 613
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 43.6 bits (98), Expect = 0.001
Identities = 26/80 (32%), Positives = 39/80 (48%)
Frame = +2
Query: 374 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXF 553
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 554 AIQYGSGXLSGFLSTDDVTV 613
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>AF338816-1|AAK38374.1| 476|Homo sapiens beta-site APP cleaving
enzyme type B protein.
Length = 476
Score = 43.6 bits (98), Expect = 0.001
Identities = 26/80 (32%), Positives = 39/80 (48%)
Frame = +2
Query: 374 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXF 553
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 554 AIQYGSGXLSGFLSTDDVTV 613
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic
proteinase Asp 2 protein.
Length = 501
Score = 43.6 bits (98), Expect = 0.001
Identities = 26/80 (32%), Positives = 39/80 (48%)
Frame = +2
Query: 374 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXF 553
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 554 AIQYGSGXLSGFLSTDDVTV 613
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase
protein.
Length = 501
Score = 43.6 bits (98), Expect = 0.001
Identities = 26/80 (32%), Positives = 39/80 (48%)
Frame = +2
Query: 374 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXF 553
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 554 AIQYGSGXLSGFLSTDDVTV 613
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2
protein.
Length = 501
Score = 43.6 bits (98), Expect = 0.001
Identities = 26/80 (32%), Positives = 39/80 (48%)
Frame = +2
Query: 374 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXF 553
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 554 AIQYGSGXLSGFLSTDDVTV 613
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein.
Length = 488
Score = 43.6 bits (98), Expect = 0.001
Identities = 26/80 (32%), Positives = 39/80 (48%)
Frame = +2
Query: 374 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXF 553
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 62 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 115
Query: 554 AIQYGSGXLSGFLSTDDVTV 613
+ Y G G L TD V++
Sbjct: 116 YVPYTQGKWEGELGTDLVSI 135
>AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving
enzyme protein.
Length = 501
Score = 43.6 bits (98), Expect = 0.001
Identities = 26/80 (32%), Positives = 39/80 (48%)
Frame = +2
Query: 374 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXF 553
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 554 AIQYGSGXLSGFLSTDDVTV 613
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>AB050436-1|BAB40931.1| 476|Homo sapiens beta-site APP cleaving
enzyme I-476 protein.
Length = 476
Score = 43.6 bits (98), Expect = 0.001
Identities = 26/80 (32%), Positives = 39/80 (48%)
Frame = +2
Query: 374 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXF 553
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 554 AIQYGSGXLSGFLSTDDVTV 613
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein.
Length = 532
Score = 43.6 bits (98), Expect = 0.001
Identities = 26/80 (32%), Positives = 39/80 (48%)
Frame = +2
Query: 374 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXF 553
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 106 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 159
Query: 554 AIQYGSGXLSGFLSTDDVTV 613
+ Y G G L TD V++
Sbjct: 160 YVPYTQGKWEGELGTDLVSI 179
>AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving
enzyme type C protein.
Length = 457
Score = 41.9 bits (94), Expect = 0.003
Identities = 25/76 (32%), Positives = 36/76 (47%)
Frame = +2
Query: 374 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXF 553
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 554 AIQYGSGXLSGFLSTD 601
+ Y G G L TD
Sbjct: 129 YVPYTQGKWEGELGTD 144
>AB050438-1|BAB40933.1| 432|Homo sapiens beta-site APP cleaving
enzyme I-432 protein.
Length = 432
Score = 41.9 bits (94), Expect = 0.003
Identities = 25/76 (32%), Positives = 36/76 (47%)
Frame = +2
Query: 374 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXF 553
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 554 AIQYGSGXLSGFLSTD 601
+ Y G G L TD
Sbjct: 129 YVPYTQGKWEGELGTD 144
>AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving
enzyme I-457 protein.
Length = 457
Score = 41.9 bits (94), Expect = 0.003
Identities = 25/76 (32%), Positives = 36/76 (47%)
Frame = +2
Query: 374 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXF 553
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 554 AIQYGSGXLSGFLSTD 601
+ Y G G L TD
Sbjct: 129 YVPYTQGKWEGELGTD 144
>BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 41.1 bits (92), Expect = 0.005
Identities = 25/80 (31%), Positives = 38/80 (47%)
Frame = +2
Query: 374 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXF 553
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLFSTYRDLRKGV 128
Query: 554 AIQYGSGXLSGFLSTDDVTV 613
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>AL365205-3|CAM16152.1| 86|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 86
Score = 38.7 bits (86), Expect = 0.029
Identities = 28/70 (40%), Positives = 37/70 (52%), Gaps = 9/70 (12%)
Frame = +2
Query: 221 SVMALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQ 373
+V+ RVPL + K+ R E G E LR KYD + EP++ Y+DA
Sbjct: 18 AVICKQRVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAA 76
Query: 374 YYGVISIGTP 403
Y+G ISIGTP
Sbjct: 77 YFGEISIGTP 86
>AL163285-1|CAB90554.1| 415|Homo sapiens beta-site APP-cleaving
enzyme 2, EC 3.4.23. protein.
Length = 415
Score = 36.7 bits (81), Expect = 0.12
Identities = 20/66 (30%), Positives = 33/66 (50%)
Frame = +2
Query: 416 KVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTXFAIQYGSGXLSGFLS 595
+++ DTGSSN V Y + +D+ +S TY + G ++Y G +GF+
Sbjct: 3 QILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVG 56
Query: 596 TDDVTV 613
D VT+
Sbjct: 57 EDLVTI 62
>AB089958-1|BAC81826.1| 127|Homo sapiens beta-site APP cleaving
enzyme isoform I-127 protein.
Length = 127
Score = 36.7 bits (81), Expect = 0.12
Identities = 19/53 (35%), Positives = 29/53 (54%)
Frame = +2
Query: 374 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTY 532
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 121
>BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain
containing 11 protein.
Length = 514
Score = 30.7 bits (66), Expect = 7.6
Identities = 12/26 (46%), Positives = 18/26 (69%)
Frame = -1
Query: 439 GSGVEYHLERLRRRADTDHSVVLSIK 362
G G E+HLER+RR ++++ SIK
Sbjct: 30 GQGAEHHLERIRRSHQKHNAILASIK 55
>BC035605-1|AAH35605.1| 578|Homo sapiens schlafen family member 12
protein.
Length = 578
Score = 25.4 bits (53), Expect(2) = 9.5
Identities = 12/51 (23%), Positives = 23/51 (45%)
Frame = -3
Query: 365 QDNLTMVRVKGQSHRILISTAPVQCQPHESGFSQFSYDVMAPYIVPLRSWR 213
+DN M + + + ++ P +E SQ + + AP+ PL W+
Sbjct: 325 KDNRVMQLTRKEWIQFMVEAEPKFSSSYEEVISQINTSLPAPHSWPLLEWQ 375
Score = 23.4 bits (48), Expect(2) = 9.5
Identities = 8/27 (29%), Positives = 11/27 (40%)
Frame = -3
Query: 512 CRTCCAANKRCWCSGTFWKAPRGWRIR 432
C CA +C F K P W ++
Sbjct: 299 CGYVCALRVERFCCAVFAKEPDSWHVK 325
>AK001122-1|BAA91512.1| 578|Homo sapiens protein ( Homo sapiens
cDNA FLJ10260 fis, clone HEMBB1000973, moderately
similar to Mus musculus schlafen3 mRNA. ).
Length = 578
Score = 25.4 bits (53), Expect(2) = 9.5
Identities = 12/51 (23%), Positives = 23/51 (45%)
Frame = -3
Query: 365 QDNLTMVRVKGQSHRILISTAPVQCQPHESGFSQFSYDVMAPYIVPLRSWR 213
+DN M + + + ++ P +E SQ + + AP+ PL W+
Sbjct: 325 KDNRVMQLTRKEWIQFMVEAEPKFSSSYEEVISQINASLPAPHSWPLLEWQ 375
Score = 23.4 bits (48), Expect(2) = 9.5
Identities = 8/27 (29%), Positives = 11/27 (40%)
Frame = -3
Query: 512 CRTCCAANKRCWCSGTFWKAPRGWRIR 432
C CA +C F K P W ++
Sbjct: 299 CGYVCALRVERFCCAVFAKEPDSWHVK 325
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 93,744,559
Number of Sequences: 237096
Number of extensions: 1912633
Number of successful extensions: 3735
Number of sequences better than 10.0: 72
Number of HSP's better than 10.0 without gapping: 3542
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3675
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11770329464
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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