Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP21_F_J16
(908 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein. 204 3e-52
M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein. 204 3e-52
M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein. 204 3e-52
CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein. 204 3e-52
BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal ... 204 3e-52
BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal ... 204 3e-52
BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein. 204 3e-52
BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic pepti... 176 8e-44
AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4 pro... 176 1e-43
AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor prot... 176 1e-43
AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein. 176 1e-43
BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein. 159 1e-38
AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3 pro... 159 1e-38
M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein. 158 3e-38
J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein. 158 3e-38
BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein. 158 3e-38
BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein. 158 3e-38
BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein. 158 3e-38
AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein. 158 3e-38
AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternativ... 158 3e-38
U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein. 154 4e-37
M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein. 154 4e-37
M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein. 154 4e-37
J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein. 154 4e-37
BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinog... 154 4e-37
AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinog... 154 4e-37
M26901-1|AAA60364.1| 403|Homo sapiens renin protein. 153 8e-37
M10152-1|AAD03461.1| 406|Homo sapiens renin protein. 153 8e-37
L00073-1|AAA60363.1| 406|Homo sapiens renin protein. 153 8e-37
CR536498-1|CAG38737.1| 406|Homo sapiens REN protein. 153 8e-37
BC047752-1|AAH47752.1| 406|Homo sapiens renin protein. 153 8e-37
BC033474-1|AAH33474.1| 406|Homo sapiens renin protein. 153 8e-37
AY436324-1|AAR03502.1| 403|Homo sapiens renin protein. 153 8e-37
AL592146-1|CAI16594.1| 406|Homo sapiens renin protein. 153 8e-37
AL592114-1|CAH71224.1| 406|Homo sapiens renin protein. 153 8e-37
J00287-1|AAA98529.1| 388|Homo sapiens PEP protein. 147 4e-35
BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I (... 147 4e-35
M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein. 146 1e-34
X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mR... 100 1e-20
BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving ... 65 4e-10
AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein. 65 4e-10
AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein. 65 4e-10
AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic ... 65 4e-10
AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1 pro... 65 4e-10
AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein. 65 4e-10
AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein. 65 4e-10
AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein. 65 4e-10
AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein. 65 4e-10
AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease ... 65 4e-10
AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein. 65 4e-10
AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens ... 64 9e-10
BC042578-1|AAH42578.1| 104|Homo sapiens PGC protein protein. 60 1e-08
DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving ... 56 1e-07
BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving ... 56 1e-07
AF338816-1|AAK38374.1| 476|Homo sapiens beta-site APP cleaving ... 56 1e-07
AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic ... 56 1e-07
AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase prot... 56 1e-07
AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2 pro... 56 1e-07
AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein. 56 1e-07
AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving ... 56 1e-07
AB050436-1|BAB40931.1| 476|Homo sapiens beta-site APP cleaving ... 56 1e-07
AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein. 56 1e-07
BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving ... 54 7e-07
AL163285-1|CAB90554.1| 415|Homo sapiens beta-site APP-cleaving ... 48 4e-05
AL365205-2|CAI95135.1| 140|Homo sapiens progastricsin (pepsinog... 43 0.002
AB050438-1|BAB40933.1| 432|Homo sapiens beta-site APP cleaving ... 42 0.002
AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving ... 42 0.003
AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving ... 42 0.003
AL365205-3|CAM16152.1| 86|Homo sapiens progastricsin (pepsinog... 39 0.029
AB089958-1|BAC81826.1| 127|Homo sapiens beta-site APP cleaving ... 37 0.12
AF141344-1|AAG49447.1| 119|Homo sapiens LYST-interacting protei... 32 2.5
AK055141-1|BAB70862.1| 260|Homo sapiens protein ( Homo sapiens ... 32 3.3
BC126459-1|AAI26460.1| 257|Homo sapiens chromosome 10 open read... 31 5.8
AL121928-10|CAI12523.1| 257|Homo sapiens novel protein protein. 31 5.8
AK024342-1|BAB14892.1| 257|Homo sapiens protein ( Homo sapiens ... 31 5.8
BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain cont... 31 7.6
BC035605-1|AAH35605.1| 578|Homo sapiens schlafen family member ... 25 9.5
AK001122-1|BAA91512.1| 578|Homo sapiens protein ( Homo sapiens ... 25 9.5
>X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 204 bits (499), Expect = 3e-52
Identities = 109/203 (53%), Positives = 131/203 (64%), Gaps = 22/203 (10%)
Frame = +1
Query: 199 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 345
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 346 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 525
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 526 YVANGTQFAIQYGSGSLSGFLSTDDVTV-----------GGLKVRRQTFAXAVSEPGLAF 672
YV NGT F I YGSGSLSG+LS D V+V GG+KV RQ F A +PG+ F
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITF 190
Query: 673 VAAKFDGILGMAFSTIAVDHVXP 741
+AAKFDGILGMA+ I+V++V P
Sbjct: 191 IAAKFDGILGMAYPRISVNNVLP 213
Score = 32.7 bits (71), Expect = 1.9
Identities = 15/25 (60%), Positives = 19/25 (76%), Gaps = 1/25 (4%)
Frame = +2
Query: 740 PVFDNMVAQGLVXP-VFSFYLNRXP 811
PVFDN++ Q LV +FSFYL+R P
Sbjct: 213 PVFDNLMQQKLVDQNIFSFYLSRDP 237
>M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 204 bits (499), Expect = 3e-52
Identities = 109/203 (53%), Positives = 131/203 (64%), Gaps = 22/203 (10%)
Frame = +1
Query: 199 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 345
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 346 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 525
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 526 YVANGTQFAIQYGSGSLSGFLSTDDVTV-----------GGLKVRRQTFAXAVSEPGLAF 672
YV NGT F I YGSGSLSG+LS D V+V GG+KV RQ F A +PG+ F
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITF 190
Query: 673 VAAKFDGILGMAFSTIAVDHVXP 741
+AAKFDGILGMA+ I+V++V P
Sbjct: 191 IAAKFDGILGMAYPRISVNNVLP 213
Score = 32.7 bits (71), Expect = 1.9
Identities = 15/25 (60%), Positives = 19/25 (76%), Gaps = 1/25 (4%)
Frame = +2
Query: 740 PVFDNMVAQGLVXP-VFSFYLNRXP 811
PVFDN++ Q LV +FSFYL+R P
Sbjct: 213 PVFDNLMQQKLVDQNIFSFYLSRDP 237
>M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 204 bits (499), Expect = 3e-52
Identities = 109/203 (53%), Positives = 131/203 (64%), Gaps = 22/203 (10%)
Frame = +1
Query: 199 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 345
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 346 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 525
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 526 YVANGTQFAIQYGSGSLSGFLSTDDVTV-----------GGLKVRRQTFAXAVSEPGLAF 672
YV NGT F I YGSGSLSG+LS D V+V GG+KV RQ F A +PG+ F
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITF 190
Query: 673 VAAKFDGILGMAFSTIAVDHVXP 741
+AAKFDGILGMA+ I+V++V P
Sbjct: 191 IAAKFDGILGMAYPRISVNNVLP 213
Score = 32.7 bits (71), Expect = 1.9
Identities = 15/25 (60%), Positives = 19/25 (76%), Gaps = 1/25 (4%)
Frame = +2
Query: 740 PVFDNMVAQGLVXP-VFSFYLNRXP 811
PVFDN++ Q LV +FSFYL+R P
Sbjct: 213 PVFDNLMQQKLVDQNIFSFYLSRDP 237
>CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 204 bits (499), Expect = 3e-52
Identities = 109/203 (53%), Positives = 131/203 (64%), Gaps = 22/203 (10%)
Frame = +1
Query: 199 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 345
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 346 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 525
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 526 YVANGTQFAIQYGSGSLSGFLSTDDVTV-----------GGLKVRRQTFAXAVSEPGLAF 672
YV NGT F I YGSGSLSG+LS D V+V GG+KV RQ F A +PG+ F
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITF 190
Query: 673 VAAKFDGILGMAFSTIAVDHVXP 741
+AAKFDGILGMA+ I+V++V P
Sbjct: 191 IAAKFDGILGMAYPRISVNNVLP 213
Score = 32.7 bits (71), Expect = 1.9
Identities = 15/25 (60%), Positives = 19/25 (76%), Gaps = 1/25 (4%)
Frame = +2
Query: 740 PVFDNMVAQGLVXP-VFSFYLNRXP 811
PVFDN++ Q LV +FSFYL+R P
Sbjct: 213 PVFDNLMQQKLVDQNIFSFYLSRDP 237
>BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 204 bits (499), Expect = 3e-52
Identities = 109/203 (53%), Positives = 131/203 (64%), Gaps = 22/203 (10%)
Frame = +1
Query: 199 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 345
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 346 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 525
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 526 YVANGTQFAIQYGSGSLSGFLSTDDVTV-----------GGLKVRRQTFAXAVSEPGLAF 672
YV NGT F I YGSGSLSG+LS D V+V GG+KV RQ F A +PG+ F
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITF 190
Query: 673 VAAKFDGILGMAFSTIAVDHVXP 741
+AAKFDGILGMA+ I+V++V P
Sbjct: 191 IAAKFDGILGMAYPRISVNNVLP 213
Score = 32.7 bits (71), Expect = 1.9
Identities = 15/25 (60%), Positives = 19/25 (76%), Gaps = 1/25 (4%)
Frame = +2
Query: 740 PVFDNMVAQGLVXP-VFSFYLNRXP 811
PVFDN++ Q LV +FSFYL+R P
Sbjct: 213 PVFDNLMQQKLVDQNIFSFYLSRDP 237
>BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 204 bits (499), Expect = 3e-52
Identities = 109/203 (53%), Positives = 131/203 (64%), Gaps = 22/203 (10%)
Frame = +1
Query: 199 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 345
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 346 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 525
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 526 YVANGTQFAIQYGSGSLSGFLSTDDVTV-----------GGLKVRRQTFAXAVSEPGLAF 672
YV NGT F I YGSGSLSG+LS D V+V GG+KV RQ F A +PG+ F
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITF 190
Query: 673 VAAKFDGILGMAFSTIAVDHVXP 741
+AAKFDGILGMA+ I+V++V P
Sbjct: 191 IAAKFDGILGMAYPRISVNNVLP 213
Score = 32.7 bits (71), Expect = 1.9
Identities = 15/25 (60%), Positives = 19/25 (76%), Gaps = 1/25 (4%)
Frame = +2
Query: 740 PVFDNMVAQGLVXP-VFSFYLNRXP 811
PVFDN++ Q LV +FSFYL+R P
Sbjct: 213 PVFDNLMQQKLVDQNIFSFYLSRDP 237
>BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 204 bits (499), Expect = 3e-52
Identities = 109/203 (53%), Positives = 131/203 (64%), Gaps = 22/203 (10%)
Frame = +1
Query: 199 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 345
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 346 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 525
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 526 YVANGTQFAIQYGSGSLSGFLSTDDVTV-----------GGLKVRRQTFAXAVSEPGLAF 672
YV NGT F I YGSGSLSG+LS D V+V GG+KV RQ F A +PG+ F
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITF 190
Query: 673 VAAKFDGILGMAFSTIAVDHVXP 741
+AAKFDGILGMA+ I+V++V P
Sbjct: 191 IAAKFDGILGMAYPRISVNNVLP 213
Score = 32.7 bits (71), Expect = 1.9
Identities = 15/25 (60%), Positives = 19/25 (76%), Gaps = 1/25 (4%)
Frame = +2
Query: 740 PVFDNMVAQGLVXP-VFSFYLNRXP 811
PVFDN++ Q LV +FSFYL+R P
Sbjct: 213 PVFDNLMQQKLVDQNIFSFYLSRDP 237
>BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic
peptidase protein.
Length = 420
Score = 176 bits (429), Expect = 8e-44
Identities = 85/183 (46%), Positives = 117/183 (63%), Gaps = 5/183 (2%)
Frame = +1
Query: 208 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 372
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRTLNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 373 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFA 552
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S ++ ANGT+FA
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFA 138
Query: 553 IQYGSGSLSGFLSTDDVTVGGLKVRRQTFAXAVSEPGLAFVAAKFDGILGMAFSTIAVDH 732
IQYG+G + G LS D +T+GG+K F A+ EP L F A FDGILG+ F ++V+
Sbjct: 139 IQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAHFDGILGLGFPILSVEG 198
Query: 733 VXP 741
V P
Sbjct: 199 VRP 201
Score = 38.7 bits (86), Expect = 0.029
Identities = 24/53 (45%), Positives = 27/53 (50%), Gaps = 1/53 (1%)
Frame = +2
Query: 740 PVFDNMVAQGLVX-PVFSFYLNRXPXXXXXXXXXXXXXSXPAHYRXDLVRVPL 895
P D +V QGL+ PVFSFYLNR P S PAHY L VP+
Sbjct: 201 PPMDVLVEQGLLDKPVFSFYLNRDP-EEPDGGELVLGGSDPAHYIPPLTFVPV 252
>AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4
protein.
Length = 420
Score = 176 bits (428), Expect = 1e-43
Identities = 85/183 (46%), Positives = 117/183 (63%), Gaps = 5/183 (2%)
Frame = +1
Query: 208 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 372
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 373 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFA 552
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S ++ ANGT+FA
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFA 138
Query: 553 IQYGSGSLSGFLSTDDVTVGGLKVRRQTFAXAVSEPGLAFVAAKFDGILGMAFSTIAVDH 732
IQYG+G + G LS D +T+GG+K F A+ EP L F A FDGILG+ F ++V+
Sbjct: 139 IQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAHFDGILGLGFPILSVEG 198
Query: 733 VXP 741
V P
Sbjct: 199 VRP 201
Score = 38.7 bits (86), Expect = 0.029
Identities = 24/53 (45%), Positives = 27/53 (50%), Gaps = 1/53 (1%)
Frame = +2
Query: 740 PVFDNMVAQGLVX-PVFSFYLNRXPXXXXXXXXXXXXXSXPAHYRXDLVRVPL 895
P D +V QGL+ PVFSFYLNR P S PAHY L VP+
Sbjct: 201 PPMDVLVEQGLLDKPVFSFYLNRDP-EEPDGGELVLGGSDPAHYIPPLTFVPV 252
>AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor
protein.
Length = 420
Score = 176 bits (428), Expect = 1e-43
Identities = 85/183 (46%), Positives = 117/183 (63%), Gaps = 5/183 (2%)
Frame = +1
Query: 208 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 372
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 373 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFA 552
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S ++ ANGT+FA
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFA 138
Query: 553 IQYGSGSLSGFLSTDDVTVGGLKVRRQTFAXAVSEPGLAFVAAKFDGILGMAFSTIAVDH 732
IQYG+G + G LS D +T+GG+K F A+ EP L F A FDGILG+ F ++V+
Sbjct: 139 IQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAHFDGILGLGFPILSVEG 198
Query: 733 VXP 741
V P
Sbjct: 199 VRP 201
Score = 38.7 bits (86), Expect = 0.029
Identities = 24/53 (45%), Positives = 27/53 (50%), Gaps = 1/53 (1%)
Frame = +2
Query: 740 PVFDNMVAQGLVX-PVFSFYLNRXPXXXXXXXXXXXXXSXPAHYRXDLVRVPL 895
P D +V QGL+ PVFSFYLNR P S PAHY L VP+
Sbjct: 201 PPMDVLVEQGLLDKPVFSFYLNRDP-EEPDGGELVLGGSDPAHYIPPLTFVPV 252
>AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein.
Length = 420
Score = 176 bits (428), Expect = 1e-43
Identities = 85/183 (46%), Positives = 117/183 (63%), Gaps = 5/183 (2%)
Frame = +1
Query: 208 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 372
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 373 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFA 552
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S ++ ANGT+FA
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFA 138
Query: 553 IQYGSGSLSGFLSTDDVTVGGLKVRRQTFAXAVSEPGLAFVAAKFDGILGMAFSTIAVDH 732
IQYG+G + G LS D +T+GG+K F A+ EP L F A FDGILG+ F ++V+
Sbjct: 139 IQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAHFDGILGLGFPILSVEG 198
Query: 733 VXP 741
V P
Sbjct: 199 VRP 201
Score = 38.7 bits (86), Expect = 0.029
Identities = 24/53 (45%), Positives = 27/53 (50%), Gaps = 1/53 (1%)
Frame = +2
Query: 740 PVFDNMVAQGLVX-PVFSFYLNRXPXXXXXXXXXXXXXSXPAHYRXDLVRVPL 895
P D +V QGL+ PVFSFYLNR P S PAHY L VP+
Sbjct: 201 PPMDVLVEQGLLDKPVFSFYLNRDP-EEPDGGELVLGGSDPAHYIPPLTFVPV 252
>BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein.
Length = 464
Score = 159 bits (386), Expect = 1e-38
Identities = 76/176 (43%), Positives = 111/176 (63%), Gaps = 5/176 (2%)
Frame = +1
Query: 229 LYRVPLHRMKTARTHFHEV---GTELELLRLKYDVTGPSPE--PLSNYLDAQYYGVISIG 393
L R+PL ++ R + + G EL +L G P PLS +LDAQY+G I +G
Sbjct: 22 LIRIPLRQVHPGRRTLNLLRGWGKPAELPKLGAPSPGDKPASVPLSKFLDAQYFGEIGLG 81
Query: 394 TPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGS 573
TPPQ+F V FDTGSSNLWVPS++CH+ ++ C H++++ S ++ +GT+FAIQYG+G
Sbjct: 82 TPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWFHHRFNPNASSSFKPSGTKFAIQYGTGR 141
Query: 574 LSGFLSTDDVTVGGLKVRRQTFAXAVSEPGLAFVAAKFDGILGMAFSTIAVDHVXP 741
+ G LS D +T+GG+K F A+ E L F ++ DGILG+ F ++V+ V P
Sbjct: 142 VDGILSEDKLTIGGIKGASVIFGEALWESSLVFTVSRPDGILGLGFPILSVEGVRP 197
Score = 37.1 bits (82), Expect = 0.088
Identities = 23/53 (43%), Positives = 26/53 (49%), Gaps = 1/53 (1%)
Frame = +2
Query: 740 PVFDNMVAQGLVX-PVFSFYLNRXPXXXXXXXXXXXXXSXPAHYRXDLVRVPL 895
P D +V QGL+ PVFSFY NR P S PAHY L VP+
Sbjct: 197 PPLDVLVEQGLLDKPVFSFYFNRDP-EVADGGELVLGGSDPAHYIPPLTFVPV 248
>AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3
protein.
Length = 450
Score = 159 bits (386), Expect = 1e-38
Identities = 76/176 (43%), Positives = 111/176 (63%), Gaps = 5/176 (2%)
Frame = +1
Query: 229 LYRVPLHRMKTARTHFHEV---GTELELLRLKYDVTGPSPE--PLSNYLDAQYYGVISIG 393
L R+PL ++ R + + G EL +L G P PLS +LDAQY+G I +G
Sbjct: 26 LIRIPLRQVHPGRRTLNLLRGWGKPAELPKLGAPSPGDKPASVPLSKFLDAQYFGEIGLG 85
Query: 394 TPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGS 573
TPPQ+F V FDTGSSNLWVPS++CH+ ++ C H++++ S ++ +GT+FAIQYG+G
Sbjct: 86 TPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWFHHRFNPNASSSFKPSGTKFAIQYGTGR 145
Query: 574 LSGFLSTDDVTVGGLKVRRQTFAXAVSEPGLAFVAAKFDGILGMAFSTIAVDHVXP 741
+ G LS D +T+GG+K F A+ E L F ++ DGILG+ F ++V+ V P
Sbjct: 146 VDGILSEDKLTIGGIKGASVIFGEALWESSLVFTVSRPDGILGLGFPILSVEGVRP 201
Score = 37.1 bits (82), Expect = 0.088
Identities = 23/53 (43%), Positives = 26/53 (49%), Gaps = 1/53 (1%)
Frame = +2
Query: 740 PVFDNMVAQGLVX-PVFSFYLNRXPXXXXXXXXXXXXXSXPAHYRXDLVRVPL 895
P D +V QGL+ PVFSFY NR P S PAHY L VP+
Sbjct: 201 PPLDVLVEQGLLDKPVFSFYFNRDP-EVADGGELVLGGSDPAHYIPPLTFVPV 252
>M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 158 bits (383), Expect = 3e-38
Identities = 86/194 (44%), Positives = 118/194 (60%), Gaps = 10/194 (5%)
Frame = +1
Query: 190 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 339
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 340 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 519
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 520 KTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAXAVSEPGLAFVAAKFDGIL 699
TY G F+IQYG+GSLSG + D V+V GL V Q F +V+EPG FV A+FDGIL
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGIL 185
Query: 700 GMAFSTIAVDHVXP 741
G+ + ++AV V P
Sbjct: 186 GLGYPSLAVGGVTP 199
Score = 33.1 bits (72), Expect = 1.4
Identities = 15/25 (60%), Positives = 19/25 (76%), Gaps = 1/25 (4%)
Frame = +2
Query: 740 PVFDNMVAQGLV-XPVFSFYLNRXP 811
PVFDNM+AQ LV P+FS Y++ P
Sbjct: 199 PVFDNMMAQNLVDLPMFSVYMSSNP 223
>J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein.
Length = 396
Score = 158 bits (383), Expect = 3e-38
Identities = 86/194 (44%), Positives = 118/194 (60%), Gaps = 10/194 (5%)
Frame = +1
Query: 190 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 339
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 340 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 519
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 520 KTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAXAVSEPGLAFVAAKFDGIL 699
TY G F+IQYG+GSLSG + D V+V GL V Q F +V+EPG FV A+FDGIL
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGIL 185
Query: 700 GMAFSTIAVDHVXP 741
G+ + ++AV V P
Sbjct: 186 GLGYPSLAVGGVTP 199
Score = 33.1 bits (72), Expect = 1.4
Identities = 15/25 (60%), Positives = 19/25 (76%), Gaps = 1/25 (4%)
Frame = +2
Query: 740 PVFDNMVAQGLV-XPVFSFYLNRXP 811
PVFDNM+AQ LV P+FS Y++ P
Sbjct: 199 PVFDNMMAQNLVDLPMFSVYMSSNP 223
>BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein.
Length = 363
Score = 158 bits (383), Expect = 3e-38
Identities = 86/194 (44%), Positives = 118/194 (60%), Gaps = 10/194 (5%)
Frame = +1
Query: 190 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 339
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 340 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 519
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 520 KTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAXAVSEPGLAFVAAKFDGIL 699
TY G F+IQYG+GSLSG + D V+V GL V Q F +V+EPG FV A+FDGIL
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGIL 185
Query: 700 GMAFSTIAVDHVXP 741
G+ + ++AV V P
Sbjct: 186 GLGYPSLAVGGVTP 199
Score = 33.1 bits (72), Expect = 1.4
Identities = 15/25 (60%), Positives = 19/25 (76%), Gaps = 1/25 (4%)
Frame = +2
Query: 740 PVFDNMVAQGLV-XPVFSFYLNRXP 811
PVFDNM+AQ LV P+FS Y++ P
Sbjct: 199 PVFDNMMAQNLVDLPMFSVYMSSNP 223
>BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 158 bits (383), Expect = 3e-38
Identities = 86/194 (44%), Positives = 118/194 (60%), Gaps = 10/194 (5%)
Frame = +1
Query: 190 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 339
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 340 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 519
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 520 KTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAXAVSEPGLAFVAAKFDGIL 699
TY G F+IQYG+GSLSG + D V+V GL V Q F +V+EPG FV A+FDGIL
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGIL 185
Query: 700 GMAFSTIAVDHVXP 741
G+ + ++AV V P
Sbjct: 186 GLGYPSLAVGGVTP 199
Score = 33.1 bits (72), Expect = 1.4
Identities = 15/25 (60%), Positives = 19/25 (76%), Gaps = 1/25 (4%)
Frame = +2
Query: 740 PVFDNMVAQGLV-XPVFSFYLNRXP 811
PVFDNM+AQ LV P+FS Y++ P
Sbjct: 199 PVFDNMMAQNLVDLPMFSVYMSSNP 223
>BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 158 bits (383), Expect = 3e-38
Identities = 86/194 (44%), Positives = 118/194 (60%), Gaps = 10/194 (5%)
Frame = +1
Query: 190 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 339
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 340 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 519
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 520 KTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAXAVSEPGLAFVAAKFDGIL 699
TY G F+IQYG+GSLSG + D V+V GL V Q F +V+EPG FV A+FDGIL
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGIL 185
Query: 700 GMAFSTIAVDHVXP 741
G+ + ++AV V P
Sbjct: 186 GLGYPSLAVGGVTP 199
Score = 33.1 bits (72), Expect = 1.4
Identities = 15/25 (60%), Positives = 19/25 (76%), Gaps = 1/25 (4%)
Frame = +2
Query: 740 PVFDNMVAQGLV-XPVFSFYLNRXP 811
PVFDNM+AQ LV P+FS Y++ P
Sbjct: 199 PVFDNMMAQNLVDLPMFSVYMSSNP 223
>AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein.
Length = 396
Score = 158 bits (383), Expect = 3e-38
Identities = 86/194 (44%), Positives = 118/194 (60%), Gaps = 10/194 (5%)
Frame = +1
Query: 190 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 339
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 340 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 519
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 520 KTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAXAVSEPGLAFVAAKFDGIL 699
TY G F+IQYG+GSLSG + D V+V GL V Q F +V+EPG FV A+FDGIL
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGIL 185
Query: 700 GMAFSTIAVDHVXP 741
G+ + ++AV V P
Sbjct: 186 GLGYPSLAVGGVTP 199
Score = 33.1 bits (72), Expect = 1.4
Identities = 15/25 (60%), Positives = 19/25 (76%), Gaps = 1/25 (4%)
Frame = +2
Query: 740 PVFDNMVAQGLV-XPVFSFYLNRXP 811
PVFDNM+AQ LV P+FS Y++ P
Sbjct: 199 PVFDNMMAQNLVDLPMFSVYMSSNP 223
>AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternative
protein.
Length = 363
Score = 158 bits (383), Expect = 3e-38
Identities = 86/194 (44%), Positives = 118/194 (60%), Gaps = 10/194 (5%)
Frame = +1
Query: 190 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 339
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 340 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 519
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 520 KTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAXAVSEPGLAFVAAKFDGIL 699
TY G F+IQYG+GSLSG + D V+V GL V Q F +V+EPG FV A+FDGIL
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGIL 185
Query: 700 GMAFSTIAVDHVXP 741
G+ + ++AV V P
Sbjct: 186 GLGYPSLAVGGVTP 199
Score = 33.1 bits (72), Expect = 1.4
Identities = 15/25 (60%), Positives = 19/25 (76%), Gaps = 1/25 (4%)
Frame = +2
Query: 740 PVFDNMVAQGLV-XPVFSFYLNRXP 811
PVFDNM+AQ LV P+FS Y++ P
Sbjct: 199 PVFDNMMAQNLVDLPMFSVYMSSNP 223
>U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein.
Length = 388
Score = 154 bits (374), Expect = 4e-37
Identities = 87/205 (42%), Positives = 123/205 (60%), Gaps = 12/205 (5%)
Frame = +1
Query: 226 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 378
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 379 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQ 558
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 559 YGSGSLSGFLSTDDVTVGGLKVRRQTFAXAVSEPGLAFVAAKFDGILGMAFSTIAVDH-- 732
YGSGSL+GF D +TV ++V Q F + +EPG FV A+FDGI+G+A+ ++VD
Sbjct: 134 YGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEAT 193
Query: 733 -VXPGVRQHGGSGTRAXRLLVLSQQ 804
G+ Q G + + + +QQ
Sbjct: 194 TAMQGMVQEGALTSPVFSVYLSNQQ 218
>M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein.
Length = 388
Score = 154 bits (374), Expect = 4e-37
Identities = 87/205 (42%), Positives = 123/205 (60%), Gaps = 12/205 (5%)
Frame = +1
Query: 226 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 378
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 379 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQ 558
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 559 YGSGSLSGFLSTDDVTVGGLKVRRQTFAXAVSEPGLAFVAAKFDGILGMAFSTIAVDH-- 732
YGSGSL+GF D +TV ++V Q F + +EPG FV A+FDGI+G+A+ ++VD
Sbjct: 134 YGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEAT 193
Query: 733 -VXPGVRQHGGSGTRAXRLLVLSQQ 804
G+ Q G + + + +QQ
Sbjct: 194 TAMQGMVQEGALTSPVFSVYLSNQQ 218
>M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein.
Length = 385
Score = 154 bits (374), Expect = 4e-37
Identities = 87/205 (42%), Positives = 123/205 (60%), Gaps = 12/205 (5%)
Frame = +1
Query: 226 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 378
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 14 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 72
Query: 379 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQ 558
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 73 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 130
Query: 559 YGSGSLSGFLSTDDVTVGGLKVRRQTFAXAVSEPGLAFVAAKFDGILGMAFSTIAVDH-- 732
YGSGSL+GF D +TV ++V Q F + +EPG FV A+FDGI+G+A+ ++VD
Sbjct: 131 YGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEAT 190
Query: 733 -VXPGVRQHGGSGTRAXRLLVLSQQ 804
G+ Q G + + + +QQ
Sbjct: 191 TAMQGMVQEGALTSPVFSVYLSNQQ 215
>J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein.
Length = 388
Score = 154 bits (374), Expect = 4e-37
Identities = 87/205 (42%), Positives = 123/205 (60%), Gaps = 12/205 (5%)
Frame = +1
Query: 226 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 378
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 379 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQ 558
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 559 YGSGSLSGFLSTDDVTVGGLKVRRQTFAXAVSEPGLAFVAAKFDGILGMAFSTIAVDH-- 732
YGSGSL+GF D +TV ++V Q F + +EPG FV A+FDGI+G+A+ ++VD
Sbjct: 134 YGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEAT 193
Query: 733 -VXPGVRQHGGSGTRAXRLLVLSQQ 804
G+ Q G + + + +QQ
Sbjct: 194 TAMQGMVQEGALTSPVFSVYLSNQQ 218
>BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 154 bits (374), Expect = 4e-37
Identities = 87/205 (42%), Positives = 123/205 (60%), Gaps = 12/205 (5%)
Frame = +1
Query: 226 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 378
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 379 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQ 558
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 559 YGSGSLSGFLSTDDVTVGGLKVRRQTFAXAVSEPGLAFVAAKFDGILGMAFSTIAVDH-- 732
YGSGSL+GF D +TV ++V Q F + +EPG FV A+FDGI+G+A+ ++VD
Sbjct: 134 YGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEAT 193
Query: 733 -VXPGVRQHGGSGTRAXRLLVLSQQ 804
G+ Q G + + + +QQ
Sbjct: 194 TAMQGMVQEGALTSPVFSVYLSNQQ 218
>AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 154 bits (374), Expect = 4e-37
Identities = 87/205 (42%), Positives = 123/205 (60%), Gaps = 12/205 (5%)
Frame = +1
Query: 226 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 378
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 379 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQ 558
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 559 YGSGSLSGFLSTDDVTVGGLKVRRQTFAXAVSEPGLAFVAAKFDGILGMAFSTIAVDH-- 732
YGSGSL+GF D +TV ++V Q F + +EPG FV A+FDGI+G+A+ ++VD
Sbjct: 134 YGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEAT 193
Query: 733 -VXPGVRQHGGSGTRAXRLLVLSQQ 804
G+ Q G + + + +QQ
Sbjct: 194 TAMQGMVQEGALTSPVFSVYLSNQQ 218
>M26901-1|AAA60364.1| 403|Homo sapiens renin protein.
Length = 403
Score = 153 bits (371), Expect = 8e-37
Identities = 69/132 (52%), Positives = 90/132 (68%)
Frame = +1
Query: 346 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 525
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 526 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAXAVSEPGLAFVAAKFDGILGM 705
Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F P L F+ A+FDG++GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPFMLAQFDGVVGM 196
Query: 706 AFSTIAVDHVXP 741
F A+ V P
Sbjct: 197 GFIEQAIGRVTP 208
Score = 33.1 bits (72), Expect = 1.4
Identities = 19/55 (34%), Positives = 27/55 (49%), Gaps = 1/55 (1%)
Frame = +2
Query: 740 PVFDNMVAQG-LVXPVFSFYLNRXPXXXXXXXXXXXXXSXPAHYRXDLVRVPLLR 901
P+FDN+++QG L VFSFY NR S P HY + + L++
Sbjct: 208 PIFDNIISQGVLKEDVFSFYYNR--NSQSLGGQIVLGGSDPQHYEGNFHYINLIK 260
>M10152-1|AAD03461.1| 406|Homo sapiens renin protein.
Length = 406
Score = 153 bits (371), Expect = 8e-37
Identities = 69/132 (52%), Positives = 90/132 (68%)
Frame = +1
Query: 346 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 525
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 526 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAXAVSEPGLAFVAAKFDGILGM 705
Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F P L F+ A+FDG++GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPFMLAEFDGVVGM 196
Query: 706 AFSTIAVDHVXP 741
F A+ V P
Sbjct: 197 GFIEQAIGRVTP 208
Score = 33.1 bits (72), Expect = 1.4
Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
Frame = +2
Query: 740 PVFDNMVAQG-LVXPVFSFYLNR-XPXXXXXXXXXXXXXSXPAHYRXDLVRVPLLR 901
P+FDN+++QG L VFSFY NR S P HY + + L++
Sbjct: 208 PIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIK 263
>L00073-1|AAA60363.1| 406|Homo sapiens renin protein.
Length = 406
Score = 153 bits (371), Expect = 8e-37
Identities = 69/132 (52%), Positives = 90/132 (68%)
Frame = +1
Query: 346 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 525
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 526 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAXAVSEPGLAFVAAKFDGILGM 705
Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F P L F+ A+FDG++GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPFMLAEFDGVVGM 196
Query: 706 AFSTIAVDHVXP 741
F A+ V P
Sbjct: 197 GFIEQAIGRVTP 208
Score = 33.1 bits (72), Expect = 1.4
Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
Frame = +2
Query: 740 PVFDNMVAQG-LVXPVFSFYLNR-XPXXXXXXXXXXXXXSXPAHYRXDLVRVPLLR 901
P+FDN+++QG L VFSFY NR S P HY + + L++
Sbjct: 208 PIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIK 263
>CR536498-1|CAG38737.1| 406|Homo sapiens REN protein.
Length = 406
Score = 153 bits (371), Expect = 8e-37
Identities = 69/132 (52%), Positives = 90/132 (68%)
Frame = +1
Query: 346 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 525
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 526 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAXAVSEPGLAFVAAKFDGILGM 705
Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F P L F+ A+FDG++GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPFMLAEFDGVVGM 196
Query: 706 AFSTIAVDHVXP 741
F A+ V P
Sbjct: 197 GFIEQAIGRVTP 208
Score = 33.1 bits (72), Expect = 1.4
Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
Frame = +2
Query: 740 PVFDNMVAQG-LVXPVFSFYLNR-XPXXXXXXXXXXXXXSXPAHYRXDLVRVPLLR 901
P+FDN+++QG L VFSFY NR S P HY + + L++
Sbjct: 208 PIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIK 263
>BC047752-1|AAH47752.1| 406|Homo sapiens renin protein.
Length = 406
Score = 153 bits (371), Expect = 8e-37
Identities = 69/132 (52%), Positives = 90/132 (68%)
Frame = +1
Query: 346 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 525
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 526 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAXAVSEPGLAFVAAKFDGILGM 705
Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F P L F+ A+FDG++GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPFMLAEFDGVVGM 196
Query: 706 AFSTIAVDHVXP 741
F A+ V P
Sbjct: 197 GFIEQAIGRVTP 208
Score = 33.1 bits (72), Expect = 1.4
Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
Frame = +2
Query: 740 PVFDNMVAQG-LVXPVFSFYLNR-XPXXXXXXXXXXXXXSXPAHYRXDLVRVPLLR 901
P+FDN+++QG L VFSFY NR S P HY + + L++
Sbjct: 208 PIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIK 263
>BC033474-1|AAH33474.1| 406|Homo sapiens renin protein.
Length = 406
Score = 153 bits (371), Expect = 8e-37
Identities = 69/132 (52%), Positives = 90/132 (68%)
Frame = +1
Query: 346 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 525
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 526 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAXAVSEPGLAFVAAKFDGILGM 705
Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F P L F+ A+FDG++GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPFMLAEFDGVVGM 196
Query: 706 AFSTIAVDHVXP 741
F A+ V P
Sbjct: 197 GFIEQAIGRVTP 208
Score = 33.1 bits (72), Expect = 1.4
Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
Frame = +2
Query: 740 PVFDNMVAQG-LVXPVFSFYLNR-XPXXXXXXXXXXXXXSXPAHYRXDLVRVPLLR 901
P+FDN+++QG L VFSFY NR S P HY + + L++
Sbjct: 208 PIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIK 263
>AY436324-1|AAR03502.1| 403|Homo sapiens renin protein.
Length = 403
Score = 153 bits (371), Expect = 8e-37
Identities = 69/132 (52%), Positives = 90/132 (68%)
Frame = +1
Query: 346 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 525
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 526 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAXAVSEPGLAFVAAKFDGILGM 705
Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F P L F+ A+FDG++GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPFMLAEFDGVVGM 196
Query: 706 AFSTIAVDHVXP 741
F A+ V P
Sbjct: 197 GFIEQAIGRVTP 208
Score = 33.1 bits (72), Expect = 1.4
Identities = 19/55 (34%), Positives = 27/55 (49%), Gaps = 1/55 (1%)
Frame = +2
Query: 740 PVFDNMVAQG-LVXPVFSFYLNRXPXXXXXXXXXXXXXSXPAHYRXDLVRVPLLR 901
P+FDN+++QG L VFSFY NR S P HY + + L++
Sbjct: 208 PIFDNIISQGVLKEDVFSFYYNR--NSQSLGGQIVLGGSDPQHYEGNFHYINLIK 260
>AL592146-1|CAI16594.1| 406|Homo sapiens renin protein.
Length = 406
Score = 153 bits (371), Expect = 8e-37
Identities = 69/132 (52%), Positives = 90/132 (68%)
Frame = +1
Query: 346 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 525
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 526 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAXAVSEPGLAFVAAKFDGILGM 705
Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F P L F+ A+FDG++GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPFMLAEFDGVVGM 196
Query: 706 AFSTIAVDHVXP 741
F A+ V P
Sbjct: 197 GFIEQAIGRVTP 208
Score = 33.1 bits (72), Expect = 1.4
Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
Frame = +2
Query: 740 PVFDNMVAQG-LVXPVFSFYLNR-XPXXXXXXXXXXXXXSXPAHYRXDLVRVPLLR 901
P+FDN+++QG L VFSFY NR S P HY + + L++
Sbjct: 208 PIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIK 263
>AL592114-1|CAH71224.1| 406|Homo sapiens renin protein.
Length = 406
Score = 153 bits (371), Expect = 8e-37
Identities = 69/132 (52%), Positives = 90/132 (68%)
Frame = +1
Query: 346 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 525
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 526 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAXAVSEPGLAFVAAKFDGILGM 705
Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F P L F+ A+FDG++GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPFMLAEFDGVVGM 196
Query: 706 AFSTIAVDHVXP 741
F A+ V P
Sbjct: 197 GFIEQAIGRVTP 208
Score = 33.1 bits (72), Expect = 1.4
Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
Frame = +2
Query: 740 PVFDNMVAQG-LVXPVFSFYLNR-XPXXXXXXXXXXXXXSXPAHYRXDLVRVPLLR 901
P+FDN+++QG L VFSFY NR S P HY + + L++
Sbjct: 208 PIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIK 263
>J00287-1|AAA98529.1| 388|Homo sapiens PEP protein.
Length = 388
Score = 147 bits (357), Expect = 4e-35
Identities = 82/196 (41%), Positives = 110/196 (56%), Gaps = 12/196 (6%)
Frame = +1
Query: 190 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 339
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLV 63
Query: 340 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSR 513
+PL NYLD +Y+G I IGTP Q F VVFDTGSSNLWVPS C +++AC HN+++
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYC--SSLACTNHNRFNPE 121
Query: 514 KSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAXAVSEPGLAFVAAKFDG 693
S TY + +I YG+GS++G L D V VGG+ Q F + +EPG A FDG
Sbjct: 122 DSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDG 181
Query: 694 ILGMAFSTIAVDHVXP 741
ILG+A+ +I+ P
Sbjct: 182 ILGLAYPSISSSGATP 197
>BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I
(pepsinogen A) protein.
Length = 388
Score = 147 bits (357), Expect = 4e-35
Identities = 82/196 (41%), Positives = 110/196 (56%), Gaps = 12/196 (6%)
Frame = +1
Query: 190 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 339
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLV 63
Query: 340 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSR 513
+PL NYLD +Y+G I IGTP Q F VVFDTGSSNLWVPS C +++AC HN+++
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYC--SSLACTNHNRFNPE 121
Query: 514 KSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAXAVSEPGLAFVAAKFDG 693
S TY + +I YG+GS++G L D V VGG+ Q F + +EPG A FDG
Sbjct: 122 DSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDG 181
Query: 694 ILGMAFSTIAVDHVXP 741
ILG+A+ +I+ P
Sbjct: 182 ILGLAYPSISSSGATP 197
>M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein.
Length = 388
Score = 146 bits (353), Expect = 1e-34
Identities = 81/196 (41%), Positives = 110/196 (56%), Gaps = 12/196 (6%)
Frame = +1
Query: 190 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 339
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSFRRTLSERGLLKDFLKKHNLNPARKYFPQWKAPTLV 63
Query: 340 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSR 513
+PL NYLD +Y+G I IGTP Q F V+FDTGSSNLWVPS C +++AC HN+++
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVLFDTGSSNLWVPSVYC--SSLACTNHNRFNPE 121
Query: 514 KSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAXAVSEPGLAFVAAKFDG 693
S TY + +I YG+GS++G L D V VGG+ Q F + +EPG A FDG
Sbjct: 122 DSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDG 181
Query: 694 ILGMAFSTIAVDHVXP 741
ILG+A+ +I+ P
Sbjct: 182 ILGLAYPSISSSGATP 197
>X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mRNA
fragment for renin (aa 105-401). ).
Length = 300
Score = 99.5 bits (237), Expect = 1e-20
Identities = 45/102 (44%), Positives = 63/102 (61%)
Frame = +1
Query: 436 SNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGG 615
SN+WVPS KC AC+ H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG
Sbjct: 1 SNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGG 60
Query: 616 LKVRRQTFAXAVSEPGLAFVAAKFDGILGMAFSTIAVDHVXP 741
+ V Q F P L F+ A+FDG++GM F A+ V P
Sbjct: 61 ITV-TQMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTP 101
Score = 33.1 bits (72), Expect = 1.4
Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
Frame = +2
Query: 740 PVFDNMVAQG-LVXPVFSFYLNR-XPXXXXXXXXXXXXXSXPAHYRXDLVRVPLLR 901
P+FDN+++QG L VFSFY NR S P HY + + L++
Sbjct: 101 PIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIK 156
>BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving
enzyme 2 protein.
Length = 518
Score = 64.9 bits (151), Expect = 4e-10
Identities = 40/120 (33%), Positives = 62/120 (51%), Gaps = 2/120 (1%)
Frame = +1
Query: 370 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 549
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 550 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAXAVSEPGLAFV-AAKFDGILGMAFSTIA 723
++Y GS +GF+ D VT+ G + E F+ K++GILG+A++T+A
Sbjct: 146 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLA 205
>AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein.
Length = 518
Score = 64.9 bits (151), Expect = 4e-10
Identities = 40/120 (33%), Positives = 62/120 (51%), Gaps = 2/120 (1%)
Frame = +1
Query: 370 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 549
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 550 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAXAVSEPGLAFV-AAKFDGILGMAFSTIA 723
++Y GS +GF+ D VT+ G + E F+ K++GILG+A++T+A
Sbjct: 146 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLA 205
>AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein.
Length = 439
Score = 64.9 bits (151), Expect = 4e-10
Identities = 40/120 (33%), Positives = 62/120 (51%), Gaps = 2/120 (1%)
Frame = +1
Query: 370 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 549
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 13 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 66
Query: 550 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAXAVSEPGLAFV-AAKFDGILGMAFSTIA 723
++Y GS +GF+ D VT+ G + E F+ K++GILG+A++T+A
Sbjct: 67 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLA 126
>AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic
proteinase Asp 1 protein.
Length = 518
Score = 64.9 bits (151), Expect = 4e-10
Identities = 40/120 (33%), Positives = 62/120 (51%), Gaps = 2/120 (1%)
Frame = +1
Query: 370 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 549
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 550 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAXAVSEPGLAFV-AAKFDGILGMAFSTIA 723
++Y GS +GF+ D VT+ G + E F+ K++GILG+A++T+A
Sbjct: 146 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLA 205
>AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1
protein.
Length = 518
Score = 64.9 bits (151), Expect = 4e-10
Identities = 40/120 (33%), Positives = 62/120 (51%), Gaps = 2/120 (1%)
Frame = +1
Query: 370 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 549
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 550 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAXAVSEPGLAFV-AAKFDGILGMAFSTIA 723
++Y GS +GF+ D VT+ G + E F+ K++GILG+A++T+A
Sbjct: 146 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLA 205
>AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein.
Length = 518
Score = 64.9 bits (151), Expect = 4e-10
Identities = 40/120 (33%), Positives = 62/120 (51%), Gaps = 2/120 (1%)
Frame = +1
Query: 370 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 549
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 550 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAXAVSEPGLAFV-AAKFDGILGMAFSTIA 723
++Y GS +GF+ D VT+ G + E F+ K++GILG+A++T+A
Sbjct: 146 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLA 205
>AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein.
Length = 396
Score = 64.9 bits (151), Expect = 4e-10
Identities = 40/120 (33%), Positives = 62/120 (51%), Gaps = 2/120 (1%)
Frame = +1
Query: 370 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 549
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 550 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAXAVSEPGLAFV-AAKFDGILGMAFSTIA 723
++Y GS +GF+ D VT+ G + E F+ K++GILG+A++T+A
Sbjct: 146 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLA 205
>AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein.
Length = 468
Score = 64.9 bits (151), Expect = 4e-10
Identities = 40/120 (33%), Positives = 62/120 (51%), Gaps = 2/120 (1%)
Frame = +1
Query: 370 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 549
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 550 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAXAVSEPGLAFV-AAKFDGILGMAFSTIA 723
++Y GS +GF+ D VT+ G + E F+ K++GILG+A++T+A
Sbjct: 146 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLA 205
>AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 64.9 bits (151), Expect = 4e-10
Identities = 40/120 (33%), Positives = 62/120 (51%), Gaps = 2/120 (1%)
Frame = +1
Query: 370 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 549
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 550 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAXAVSEPGLAFV-AAKFDGILGMAFSTIA 723
++Y GS +GF+ D VT+ G + E F+ K++GILG+A++T+A
Sbjct: 146 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLA 205
>AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease
protein.
Length = 518
Score = 64.9 bits (151), Expect = 4e-10
Identities = 40/120 (33%), Positives = 62/120 (51%), Gaps = 2/120 (1%)
Frame = +1
Query: 370 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 549
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 550 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAXAVSEPGLAFV-AAKFDGILGMAFSTIA 723
++Y GS +GF+ D VT+ G + E F+ K++GILG+A++T+A
Sbjct: 146 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLA 205
>AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 64.9 bits (151), Expect = 4e-10
Identities = 40/120 (33%), Positives = 62/120 (51%), Gaps = 2/120 (1%)
Frame = +1
Query: 370 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 549
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 550 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAXAVSEPGLAFV-AAKFDGILGMAFSTIA 723
++Y GS +GF+ D VT+ G + E F+ K++GILG+A++T+A
Sbjct: 146 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLA 205
>AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens
cDNA PSEC0239 fis, clone OVARC1000363, highly similar to
Homo sapiens aspartyl protease mRNA. ).
Length = 423
Score = 63.7 bits (148), Expect = 9e-10
Identities = 38/114 (33%), Positives = 60/114 (52%), Gaps = 2/114 (1%)
Frame = +1
Query: 388 IGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGS 567
IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G ++Y
Sbjct: 3 IGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDVTVKYTQ 56
Query: 568 GSLSGFLSTDDVTV-GGLKVRRQTFAXAVSEPGLAFV-AAKFDGILGMAFSTIA 723
GS +GF+ D VT+ G + E G F+ +++GILG+A++T+A
Sbjct: 57 GSWTGFVGEDLVTIPKGFNTSFLVNIATIFESGNFFLPGIQWNGILGLAYATLA 110
>BC042578-1|AAH42578.1| 104|Homo sapiens PGC protein protein.
Length = 104
Score = 60.1 bits (139), Expect = 1e-08
Identities = 38/82 (46%), Positives = 49/82 (59%), Gaps = 9/82 (10%)
Frame = +1
Query: 226 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 378
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 379 VISIGTPPQSFKVVFDTGSSNL 444
ISIGTPPQ+F V+FDTGSS L
Sbjct: 76 EISIGTPPQNFLVLFDTGSSPL 97
>DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 56.4 bits (130), Expect = 1e-07
Identities = 38/120 (31%), Positives = 61/120 (50%), Gaps = 2/120 (1%)
Frame = +1
Query: 370 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 549
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 550 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAXAVSEPGLAFV-AAKFDGILGMAFSTIA 723
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A++ IA
Sbjct: 129 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA 188
>BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 56.4 bits (130), Expect = 1e-07
Identities = 38/120 (31%), Positives = 61/120 (50%), Gaps = 2/120 (1%)
Frame = +1
Query: 370 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 549
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 550 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAXAVSEPGLAFV-AAKFDGILGMAFSTIA 723
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A++ IA
Sbjct: 129 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA 188
>AF338816-1|AAK38374.1| 476|Homo sapiens beta-site APP cleaving
enzyme type B protein.
Length = 476
Score = 56.4 bits (130), Expect = 1e-07
Identities = 38/120 (31%), Positives = 61/120 (50%), Gaps = 2/120 (1%)
Frame = +1
Query: 370 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 549
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 550 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAXAVSEPGLAFV-AAKFDGILGMAFSTIA 723
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A++ IA
Sbjct: 129 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA 188
>AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic
proteinase Asp 2 protein.
Length = 501
Score = 56.4 bits (130), Expect = 1e-07
Identities = 38/120 (31%), Positives = 61/120 (50%), Gaps = 2/120 (1%)
Frame = +1
Query: 370 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 549
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 550 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAXAVSEPGLAFV-AAKFDGILGMAFSTIA 723
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A++ IA
Sbjct: 129 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA 188
>AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase
protein.
Length = 501
Score = 56.4 bits (130), Expect = 1e-07
Identities = 38/120 (31%), Positives = 61/120 (50%), Gaps = 2/120 (1%)
Frame = +1
Query: 370 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 549
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 550 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAXAVSEPGLAFV-AAKFDGILGMAFSTIA 723
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A++ IA
Sbjct: 129 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA 188
>AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2
protein.
Length = 501
Score = 56.4 bits (130), Expect = 1e-07
Identities = 38/120 (31%), Positives = 61/120 (50%), Gaps = 2/120 (1%)
Frame = +1
Query: 370 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 549
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 550 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAXAVSEPGLAFV-AAKFDGILGMAFSTIA 723
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A++ IA
Sbjct: 129 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA 188
>AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein.
Length = 488
Score = 56.4 bits (130), Expect = 1e-07
Identities = 38/120 (31%), Positives = 61/120 (50%), Gaps = 2/120 (1%)
Frame = +1
Query: 370 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 549
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 62 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 115
Query: 550 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAXAVSEPGLAFV-AAKFDGILGMAFSTIA 723
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A++ IA
Sbjct: 116 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA 175
>AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving
enzyme protein.
Length = 501
Score = 56.4 bits (130), Expect = 1e-07
Identities = 38/120 (31%), Positives = 61/120 (50%), Gaps = 2/120 (1%)
Frame = +1
Query: 370 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 549
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 550 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAXAVSEPGLAFV-AAKFDGILGMAFSTIA 723
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A++ IA
Sbjct: 129 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA 188
>AB050436-1|BAB40931.1| 476|Homo sapiens beta-site APP cleaving
enzyme I-476 protein.
Length = 476
Score = 56.4 bits (130), Expect = 1e-07
Identities = 38/120 (31%), Positives = 61/120 (50%), Gaps = 2/120 (1%)
Frame = +1
Query: 370 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 549
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 550 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAXAVSEPGLAFV-AAKFDGILGMAFSTIA 723
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A++ IA
Sbjct: 129 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA 188
>AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein.
Length = 532
Score = 56.4 bits (130), Expect = 1e-07
Identities = 38/120 (31%), Positives = 61/120 (50%), Gaps = 2/120 (1%)
Frame = +1
Query: 370 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 549
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 106 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 159
Query: 550 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAXAVSEPGLAFV-AAKFDGILGMAFSTIA 723
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A++ IA
Sbjct: 160 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA 219
>BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 54.0 bits (124), Expect = 7e-07
Identities = 37/120 (30%), Positives = 60/120 (50%), Gaps = 2/120 (1%)
Frame = +1
Query: 370 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 549
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLFSTYRDLRKGV 128
Query: 550 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAXAVSEPGLAFV-AAKFDGILGMAFSTIA 723
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A++ IA
Sbjct: 129 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA 188
>AL163285-1|CAB90554.1| 415|Homo sapiens beta-site APP-cleaving
enzyme 2, EC 3.4.23. protein.
Length = 415
Score = 48.4 bits (110), Expect = 4e-05
Identities = 32/106 (30%), Positives = 53/106 (50%), Gaps = 2/106 (1%)
Frame = +1
Query: 412 KVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLS 591
+++ DTGSSN V Y + +D+ +S TY + G ++Y GS +GF+
Sbjct: 3 QILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVG 56
Query: 592 TDDVTV-GGLKVRRQTFAXAVSEPGLAFV-AAKFDGILGMAFSTIA 723
D VT+ G + E F+ K++GILG+A++T+A
Sbjct: 57 EDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLA 102
>AL365205-2|CAI95135.1| 140|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 140
Score = 42.7 bits (96), Expect = 0.002
Identities = 23/69 (33%), Positives = 38/69 (55%), Gaps = 3/69 (4%)
Frame = +1
Query: 607 VGGLKVRRQTFAXAVSEPGLAFVAAKFDGILGMAFSTIAVDH---VXPGVRQHGGSGTRA 777
V ++V Q F + +EPG FV A+FDGI+G+A+ ++VD G+ Q G +
Sbjct: 71 VQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEATTAMQGMVQEGALTSPV 130
Query: 778 XRLLVLSQQ 804
+ + +QQ
Sbjct: 131 FSVYLSNQQ 139
>AB050438-1|BAB40933.1| 432|Homo sapiens beta-site APP cleaving
enzyme I-432 protein.
Length = 432
Score = 42.3 bits (95), Expect = 0.002
Identities = 27/94 (28%), Positives = 42/94 (44%)
Frame = +1
Query: 370 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 549
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 550 AIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAXAV 651
+ Y G G L TD + G + + +V
Sbjct: 129 YVPYTQGKWEGELGTDLLCGAGFPLNQSEVLASV 162
>AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving
enzyme type C protein.
Length = 457
Score = 41.9 bits (94), Expect = 0.003
Identities = 25/76 (32%), Positives = 36/76 (47%)
Frame = +1
Query: 370 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 549
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 550 AIQYGSGSLSGFLSTD 597
+ Y G G L TD
Sbjct: 129 YVPYTQGKWEGELGTD 144
>AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving
enzyme I-457 protein.
Length = 457
Score = 41.9 bits (94), Expect = 0.003
Identities = 25/76 (32%), Positives = 36/76 (47%)
Frame = +1
Query: 370 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 549
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 550 AIQYGSGSLSGFLSTD 597
+ Y G G L TD
Sbjct: 129 YVPYTQGKWEGELGTD 144
>AL365205-3|CAM16152.1| 86|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 86
Score = 38.7 bits (86), Expect = 0.029
Identities = 28/70 (40%), Positives = 37/70 (52%), Gaps = 9/70 (12%)
Frame = +1
Query: 217 SVMALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQ 369
+V+ RVPL + K+ R E G E LR KYD + EP++ Y+DA
Sbjct: 18 AVICKQRVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAA 76
Query: 370 YYGVISIGTP 399
Y+G ISIGTP
Sbjct: 77 YFGEISIGTP 86
>AB089958-1|BAC81826.1| 127|Homo sapiens beta-site APP cleaving
enzyme isoform I-127 protein.
Length = 127
Score = 36.7 bits (81), Expect = 0.12
Identities = 19/53 (35%), Positives = 29/53 (54%)
Frame = +1
Query: 370 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTY 528
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 121
>AF141344-1|AAG49447.1| 119|Homo sapiens LYST-interacting protein
LIP8 protein.
Length = 119
Score = 32.3 bits (70), Expect = 2.5
Identities = 13/33 (39%), Positives = 16/33 (48%)
Frame = -2
Query: 592 WRGSRRGCRSRTVSRTGCHSRRTSWTCGCRTCC 494
W GS+R C + V + S SW CR CC
Sbjct: 8 WPGSKRECANCRVGTSSWRSSGWSWWKDCRPCC 40
>AK055141-1|BAB70862.1| 260|Homo sapiens protein ( Homo sapiens
cDNA FLJ30579 fis, clone BRAWH2006989, weakly similar to
DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT (EC
2.7.7.6). ).
Length = 260
Score = 31.9 bits (69), Expect = 3.3
Identities = 17/35 (48%), Positives = 18/35 (51%)
Frame = -2
Query: 601 HHQWRGSRRGCRSRTVSRTGCHSRRTSWTCGCRTC 497
H+ W GS R C S T S G HS SWT R C
Sbjct: 26 HNSWTGSNRACSSWTGSTRG-HS---SWTGSSRAC 56
>BC126459-1|AAI26460.1| 257|Homo sapiens chromosome 10 open reading
frame 95 protein.
Length = 257
Score = 31.1 bits (67), Expect = 5.8
Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 1/54 (1%)
Frame = +3
Query: 657 ARACLRGRQVRRDPRDGLQHYRSGPCXPRCS-TTWWLRDSCXPSSRSISTGXPG 815
+R C R R+ RR PR G + R+G C P C+ W R + S R+ G G
Sbjct: 140 SRDC-RCRRPRRWPRAGRRGRRAGACKPSCAGAAWSARGAPLCSYRTSCAGSCG 192
>AL121928-10|CAI12523.1| 257|Homo sapiens novel protein protein.
Length = 257
Score = 31.1 bits (67), Expect = 5.8
Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 1/54 (1%)
Frame = +3
Query: 657 ARACLRGRQVRRDPRDGLQHYRSGPCXPRCS-TTWWLRDSCXPSSRSISTGXPG 815
+R C R R+ RR PR G + R+G C P C+ W R + S R+ G G
Sbjct: 140 SRDC-RCRRPRRWPRAGRRGRRAGACKPSCAGAAWSARGAPLCSYRTSCAGSCG 192
>AK024342-1|BAB14892.1| 257|Homo sapiens protein ( Homo sapiens
cDNA FLJ14280 fis, clone PLACE1005584, weakly similar to
TRANS-ACTING TRANSCRIPTIONAL PROTEIN ICP0. ).
Length = 257
Score = 31.1 bits (67), Expect = 5.8
Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 1/54 (1%)
Frame = +3
Query: 657 ARACLRGRQVRRDPRDGLQHYRSGPCXPRCS-TTWWLRDSCXPSSRSISTGXPG 815
+R C R R+ RR PR G + R+G C P C+ W R + S R+ G G
Sbjct: 140 SRDC-RCRRPRRWPRAGRRGRRAGACKPSCAGAAWSARGAPLCSYRTSCAGSCG 192
>BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain
containing 11 protein.
Length = 514
Score = 30.7 bits (66), Expect = 7.6
Identities = 12/26 (46%), Positives = 18/26 (69%)
Frame = -3
Query: 435 GSGVEYHLERLRRRADTDHSVVLSIK 358
G G E+HLER+RR ++++ SIK
Sbjct: 30 GQGAEHHLERIRRSHQKHNAILASIK 55
>BC035605-1|AAH35605.1| 578|Homo sapiens schlafen family member 12
protein.
Length = 578
Score = 25.4 bits (53), Expect(2) = 9.5
Identities = 12/51 (23%), Positives = 23/51 (45%)
Frame = -2
Query: 361 QDNLTMVRVKGQSHRILISTAPVQCQPHESGFSQFSYDVMAPYIVPLRSWR 209
+DN M + + + ++ P +E SQ + + AP+ PL W+
Sbjct: 325 KDNRVMQLTRKEWIQFMVEAEPKFSSSYEEVISQINTSLPAPHSWPLLEWQ 375
Score = 23.4 bits (48), Expect(2) = 9.5
Identities = 8/27 (29%), Positives = 11/27 (40%)
Frame = -2
Query: 508 CRTCCAANKRCWCSGTFWKAPRGWRIR 428
C CA +C F K P W ++
Sbjct: 299 CGYVCALRVERFCCAVFAKEPDSWHVK 325
>AK001122-1|BAA91512.1| 578|Homo sapiens protein ( Homo sapiens
cDNA FLJ10260 fis, clone HEMBB1000973, moderately
similar to Mus musculus schlafen3 mRNA. ).
Length = 578
Score = 25.4 bits (53), Expect(2) = 9.5
Identities = 12/51 (23%), Positives = 23/51 (45%)
Frame = -2
Query: 361 QDNLTMVRVKGQSHRILISTAPVQCQPHESGFSQFSYDVMAPYIVPLRSWR 209
+DN M + + + ++ P +E SQ + + AP+ PL W+
Sbjct: 325 KDNRVMQLTRKEWIQFMVEAEPKFSSSYEEVISQINASLPAPHSWPLLEWQ 375
Score = 23.4 bits (48), Expect(2) = 9.5
Identities = 8/27 (29%), Positives = 11/27 (40%)
Frame = -2
Query: 508 CRTCCAANKRCWCSGTFWKAPRGWRIR 428
C CA +C F K P W ++
Sbjct: 299 CGYVCALRVERFCCAVFAKEPDSWHVK 325
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 119,158,622
Number of Sequences: 237096
Number of extensions: 2606288
Number of successful extensions: 6765
Number of sequences better than 10.0: 78
Number of HSP's better than 10.0 without gapping: 6020
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6677
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11770329464
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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