Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP21_F_J01
(896 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 159 2e-38
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 159 2e-38
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 159 2e-38
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 159 2e-38
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 159 2e-38
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 159 2e-38
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 159 2e-38
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 159 2e-38
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 159 2e-38
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 159 2e-38
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 158 2e-38
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 158 2e-38
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 158 2e-38
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 158 2e-38
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 158 2e-38
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 158 2e-38
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 158 2e-38
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 158 2e-38
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 158 2e-38
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 158 2e-38
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 157 7e-38
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 157 7e-38
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 155 2e-37
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 155 2e-37
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 155 3e-37
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 154 4e-37
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 154 4e-37
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 154 4e-37
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 154 4e-37
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 154 4e-37
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 154 5e-37
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 154 5e-37
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 154 5e-37
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 154 5e-37
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 154 5e-37
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 154 5e-37
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 154 5e-37
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 153 6e-37
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 153 6e-37
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 153 1e-36
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 153 1e-36
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 153 1e-36
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 153 1e-36
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 153 1e-36
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 153 1e-36
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 153 1e-36
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 153 1e-36
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 152 1e-36
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 151 3e-36
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 151 3e-36
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 151 3e-36
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 151 3e-36
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 151 3e-36
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 151 3e-36
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 151 3e-36
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 151 3e-36
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 151 3e-36
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 151 3e-36
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 151 3e-36
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 151 3e-36
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 151 3e-36
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 151 4e-36
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 151 4e-36
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 151 4e-36
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 151 4e-36
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 151 4e-36
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 151 4e-36
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 151 4e-36
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 150 6e-36
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 150 8e-36
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 148 3e-35
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 92 5e-35
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 92 5e-35
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 92 5e-35
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 146 1e-34
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 142 2e-33
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 142 2e-33
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 142 2e-33
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 142 2e-33
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 129 1e-29
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 92 1e-28
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 92 1e-28
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 105 2e-22
AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 105 2e-22
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 105 2e-22
BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 94 5e-19
BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 94 5e-19
AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 94 5e-19
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 92 2e-18
AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto red... 87 8e-17
AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens ... 74 8e-13
U33429-1|AAC50955.1| 367|Homo sapiens K+ channel beta 2 subunit... 46 1e-04
CR542287-1|CAG47082.1| 353|Homo sapiens KCNAB2 protein. 46 1e-04
BC130413-1|AAI30414.1| 367|Homo sapiens potassium voltage-gated... 46 1e-04
BC126424-1|AAI26425.1| 367|Homo sapiens potassium voltage-gated... 46 1e-04
BC110351-1|AAI10352.1| 395|Homo sapiens KCNAB2 protein protein. 46 1e-04
AL035406-6|CAI19886.1| 253|Homo sapiens potassium voltage-gated... 46 1e-04
AL035406-5|CAI19887.1| 254|Homo sapiens potassium voltage-gated... 46 1e-04
AL035406-4|CAC08512.1| 367|Homo sapiens potassium voltage-gated... 46 1e-04
AL035406-3|CAI19885.1| 353|Homo sapiens potassium voltage-gated... 46 1e-04
AK131252-1|BAD18431.1| 415|Homo sapiens protein ( Homo sapiens ... 46 1e-04
AF044253-1|AAB99859.1| 353|Homo sapiens potassium channel beta ... 46 1e-04
AF029749-1|AAB84170.1| 367|Homo sapiens potassium channel beta ... 46 1e-04
AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthas... 46 2e-04
CR542264-1|CAG47060.1| 353|Homo sapiens KCNAB2 protein. 44 8e-04
BC099634-1|AAH99634.1| 404|Homo sapiens potassium voltage-gated... 43 0.002
BC096234-1|AAH96234.1| 404|Homo sapiens potassium voltage-gated... 43 0.002
BC096232-1|AAH96232.1| 404|Homo sapiens potassium voltage-gated... 43 0.002
AF016411-1|AAB92499.1| 404|Homo sapiens KCNA3.1B protein. 43 0.002
AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto red... 38 0.049
AF026947-1|AAC52104.1| 330|Homo sapiens aflatoxin aldehyde redu... 34 0.61
Y16675-1|CAA76347.1| 330|Homo sapiens aflatoxin B1-aldehyde red... 34 0.80
BT007347-1|AAP36011.1| 330|Homo sapiens aldo-keto reductase fam... 34 0.80
BC013996-1|AAH13996.1| 330|Homo sapiens AKR7A2 protein protein. 34 0.80
BC012171-1|AAH12171.1| 330|Homo sapiens AKR7A2 protein protein. 34 0.80
BC011586-1|AAH11586.1| 330|Homo sapiens AKR7A2 protein protein. 34 0.80
BC010852-1|AAH10852.1| 330|Homo sapiens AKR7A2 protein protein. 34 0.80
BC007352-1|AAH07352.2| 358|Homo sapiens AKR7A2 protein protein. 34 0.80
BC004111-1|AAH04111.3| 330|Homo sapiens AKR7A2 protein protein. 34 0.80
AL035413-8|CAB72321.1| 330|Homo sapiens aldo-keto reductase fam... 34 0.80
BX537954-1|CAD97921.1| 2210|Homo sapiens hypothetical protein pr... 32 3.2
M64590-1|AAA36463.1| 1020|Homo sapiens glycine decarboxylase pro... 31 5.7
M63635-1|AAA36478.1| 1020|Homo sapiens glycine decarboxylase pro... 31 5.7
D90239-1|BAA14286.1| 1020|Homo sapiens glycine decarboxylase pre... 31 5.7
BC111995-1|AAI11996.1| 1020|Homo sapiens glycine dehydrogenase (... 31 5.7
BC111993-1|AAI11994.1| 1020|Homo sapiens glycine dehydrogenase (... 31 5.7
AL353718-2|CAH74116.1| 1036|Homo sapiens glycine dehydrogenase (... 31 5.7
AL162411-3|CAH69992.1| 1036|Homo sapiens glycine dehydrogenase (... 31 5.7
AF246134-1|AAK28443.2| 331|Homo sapiens glycine decarboxylase P... 31 5.7
BC071744-1|AAH71744.1| 157|Homo sapiens UTY protein protein. 31 7.5
AK092420-1|BAC03884.1| 357|Homo sapiens protein ( Homo sapiens ... 30 9.9
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 159 bits (385), Expect = 2e-38
Identities = 93/216 (43%), Positives = 131/216 (60%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--- 507
K ++G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P+++
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 125
Query: 508 ------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++ GL+ K
Sbjct: 126 EEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 186 PVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 159 bits (385), Expect = 2e-38
Identities = 93/216 (43%), Positives = 131/216 (60%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--- 507
K ++G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P+++
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 125
Query: 508 ------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++ GL+ K
Sbjct: 126 EEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 186 PVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 159 bits (385), Expect = 2e-38
Identities = 93/216 (43%), Positives = 131/216 (60%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--- 507
K ++G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P+++
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 125
Query: 508 ------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++ GL+ K
Sbjct: 126 EEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 186 PVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 159 bits (385), Expect = 2e-38
Identities = 93/216 (43%), Positives = 131/216 (60%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--- 507
K ++G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P+++
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 125
Query: 508 ------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++ GL+ K
Sbjct: 126 EEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 186 PVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 159 bits (385), Expect = 2e-38
Identities = 93/216 (43%), Positives = 131/216 (60%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--- 507
K ++G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P+++
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 125
Query: 508 ------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++ GL+ K
Sbjct: 126 EEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 186 PVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 159 bits (385), Expect = 2e-38
Identities = 93/216 (43%), Positives = 131/216 (60%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--- 507
K ++G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P+++
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 125
Query: 508 ------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++ GL+ K
Sbjct: 126 EEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 186 PVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 159 bits (385), Expect = 2e-38
Identities = 93/216 (43%), Positives = 131/216 (60%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--- 507
K ++G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P+++
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 125
Query: 508 ------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++ GL+ K
Sbjct: 126 EEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 186 PVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 159 bits (385), Expect = 2e-38
Identities = 93/216 (43%), Positives = 131/216 (60%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--- 507
K ++G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P+++
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 125
Query: 508 ------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++ GL+ K
Sbjct: 126 EEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 186 PVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 159 bits (385), Expect = 2e-38
Identities = 93/216 (43%), Positives = 131/216 (60%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--- 507
K ++G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P+++
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 125
Query: 508 ------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++ GL+ K
Sbjct: 126 EEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 186 PVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 159 bits (385), Expect = 2e-38
Identities = 93/216 (43%), Positives = 131/216 (60%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--- 507
K ++G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P+++
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 125
Query: 508 ------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++ GL+ K
Sbjct: 126 EEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 186 PVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 158 bits (384), Expect = 2e-38
Identities = 94/216 (43%), Positives = 131/216 (60%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--- 507
K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+YVDLYLIH+P+++
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 125
Query: 508 ------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
EN +L D VD TW M K GL KSIG+SNFN ++ I++ GL+ K
Sbjct: 126 EEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 186 PVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 158 bits (384), Expect = 2e-38
Identities = 94/216 (43%), Positives = 131/216 (60%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--- 507
K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+YVDLYLIH+P+++
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 125
Query: 508 ------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
EN +L D VD TW M K GL KSIG+SNFN ++ I++ GL+ K
Sbjct: 126 EEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 186 PVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 158 bits (384), Expect = 2e-38
Identities = 94/216 (43%), Positives = 131/216 (60%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--- 507
K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+YVDLYLIH+P+++
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 125
Query: 508 ------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
EN +L D VD TW M K GL KSIG+SNFN ++ I++ GL+ K
Sbjct: 126 EEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 186 PVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 158 bits (384), Expect = 2e-38
Identities = 94/216 (43%), Positives = 131/216 (60%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--- 507
K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+YVDLYLIH+P+++
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 125
Query: 508 ------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
EN +L D VD TW M K GL KSIG+SNFN ++ I++ GL+ K
Sbjct: 126 EEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 186 PVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 158 bits (384), Expect = 2e-38
Identities = 94/216 (43%), Positives = 131/216 (60%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--- 507
K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+YVDLYLIH+P+++
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 125
Query: 508 ------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
EN +L D VD TW M K GL KSIG+SNFN ++ I++ GL+ K
Sbjct: 126 EEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 186 PVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 158 bits (384), Expect = 2e-38
Identities = 94/216 (43%), Positives = 131/216 (60%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--- 507
K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+YVDLYLIH+P+++
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 125
Query: 508 ------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
EN +L D VD TW M K GL KSIG+SNFN ++ I++ GL+ K
Sbjct: 126 EEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 186 PVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 158 bits (384), Expect = 2e-38
Identities = 94/216 (43%), Positives = 131/216 (60%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+QVG A+
Sbjct: 26 GHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQVGLAI 78
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--- 507
K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+YVDLYLIH+P+++
Sbjct: 79 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 138
Query: 508 ------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
EN +L D VD TW M K GL KSIG+SNFN ++ I++ GL+ K
Sbjct: 139 EEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYK 198
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 199 PVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 234
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 158 bits (384), Expect = 2e-38
Identities = 94/216 (43%), Positives = 131/216 (60%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--- 507
K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+YVDLYLIH+P+++
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 125
Query: 508 ------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
EN +L D VD TW M K GL KSIG+SNFN ++ I++ GL+ K
Sbjct: 126 EEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 186 PVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 158 bits (384), Expect = 2e-38
Identities = 94/216 (43%), Positives = 131/216 (60%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--- 507
K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+YVDLYLIH+P+++
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 125
Query: 508 ------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
EN +L D VD TW M K GL KSIG+SNFN ++ I++ GL+ K
Sbjct: 126 EEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 186 PVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 158 bits (384), Expect = 2e-38
Identities = 94/216 (43%), Positives = 131/216 (60%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--- 507
K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+YVDLYLIH+P+++
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 125
Query: 508 ------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
EN +L D VD TW M K GL KSIG+SNFN ++ I++ GL+ K
Sbjct: 126 EEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 186 PVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 157 bits (380), Expect = 7e-38
Identities = 93/216 (43%), Positives = 131/216 (60%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--- 507
K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+YVDLYLIH+P+++
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 125
Query: 508 ------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII-DSGLE-K 660
EN +L D VD TW M K GL KSIG+SNFN ++ I+ + GL+ +
Sbjct: 126 EEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPGLKYE 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 186 PVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 157 bits (380), Expect = 7e-38
Identities = 93/216 (43%), Positives = 130/216 (60%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ PK K ++ AV A+EAGY HID+A+ Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGYHHIDSAHVYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--- 507
K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+Y DLYLIH+P+++
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYADLYLIHFPVSVKPG 125
Query: 508 ------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII-DSGLE-K 660
EN +L D VD TW M K GL KSIG+SNFN ++ I+ + GL+ +
Sbjct: 126 EEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPGLKYE 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 186 PVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 221
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 155 bits (376), Expect = 2e-37
Identities = 90/211 (42%), Positives = 128/211 (60%), Gaps = 14/211 (6%)
Frame = +1
Query: 178 VVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFS 354
V+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+QVG A+ K +
Sbjct: 1 VLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQVGLAIRSKIA 53
Query: 355 EG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM-------- 507
+G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P+++
Sbjct: 54 DGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIP 113
Query: 508 -FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQ 675
EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++ GL+ KP Q
Sbjct: 114 KDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQ 173
Query: 676 IELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
+E + Q +L FC+ DIV++AY+ GS
Sbjct: 174 VECHPYFNQRKLLDFCKSKDIVLVAYSALGS 204
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 155 bits (376), Expect = 2e-37
Identities = 89/216 (41%), Positives = 130/216 (60%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN 516
K ++G +KRE IF T+KLW ++ + + V PAL SL+ L L+YVDLYL+H+P+A+
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPG 125
Query: 517 DT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
+T + D VD TW M K GL KSIG+SNFN Q++ I++ GL+ K
Sbjct: 126 ETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + L Q +L FC+ DIV++A++ G+
Sbjct: 186 PVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGT 221
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 155 bits (375), Expect = 3e-37
Identities = 89/216 (41%), Positives = 130/216 (60%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN 516
K ++G +KRE IF T+KLW ++ + + V PAL SL+ L L+YVDLYL+H+P+A+
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPG 125
Query: 517 DT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
+T + D VD TW M K GL KSIG+SNFN Q++ I++ GL+ K
Sbjct: 126 ETPLPKDENGKVIFDTVDLCATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + L Q +L FC+ DIV++A++ G+
Sbjct: 186 PVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGT 221
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 154 bits (374), Expect = 4e-37
Identities = 89/216 (41%), Positives = 130/216 (60%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN 516
K ++G +KRE IF T+KLW ++ + + V PAL SL+ L L+YVDLYL+H+P+A+
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPG 125
Query: 517 DT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
+T + D VD TW M K GL KSIG+SNFN Q++ I++ GL+ K
Sbjct: 126 ETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + L Q +L FC+ DIV++A++ G+
Sbjct: 186 PVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGT 221
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 154 bits (374), Expect = 4e-37
Identities = 89/216 (41%), Positives = 130/216 (60%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+QVG A+
Sbjct: 11 GHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQVGLAI 63
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN 516
K ++G +KRE IF T+KLW ++ + + V PAL SL+ L L+YVDLYL+H+P+A+
Sbjct: 64 RSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPG 123
Query: 517 DT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
+T + D VD TW M K GL KSIG+SNFN Q++ I++ GL+ K
Sbjct: 124 ETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYK 183
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + L Q +L FC+ DIV++A++ G+
Sbjct: 184 PVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGT 219
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 154 bits (374), Expect = 4e-37
Identities = 89/216 (41%), Positives = 130/216 (60%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN 516
K ++G +KRE IF T+KLW ++ + + V PAL SL+ L L+YVDLYL+H+P+A+
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPG 125
Query: 517 DT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
+T + D VD TW M K GL KSIG+SNFN Q++ I++ GL+ K
Sbjct: 126 ETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + L Q +L FC+ DIV++A++ G+
Sbjct: 186 PVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGT 221
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 154 bits (374), Expect = 4e-37
Identities = 89/216 (41%), Positives = 130/216 (60%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN 516
K ++G +KRE IF T+KLW ++ + + V PAL SL+ L L+YVDLYL+H+P+A+
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPG 125
Query: 517 DT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
+T + D VD TW M K GL KSIG+SNFN Q++ I++ GL+ K
Sbjct: 126 ETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + L Q +L FC+ DIV++A++ G+
Sbjct: 186 PVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGT 221
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 154 bits (374), Expect = 4e-37
Identities = 89/216 (41%), Positives = 130/216 (60%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN 516
K ++G +KRE IF T+KLW ++ + + V PAL SL+ L L+YVDLYL+H+P+A+
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPG 125
Query: 517 DT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
+T + D VD TW M K GL KSIG+SNFN Q++ I++ GL+ K
Sbjct: 126 ETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + L Q +L FC+ DIV++A++ G+
Sbjct: 186 PVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGT 221
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 154 bits (373), Expect = 5e-37
Identities = 89/216 (41%), Positives = 128/216 (59%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+QVG A+
Sbjct: 15 GHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQVGLAI 67
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN 516
K ++G +KRE IF T+KLW+++H E V PAL SL+ L+YVDLYLIH P+++
Sbjct: 68 RSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPG 127
Query: 517 DTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
+ L D VD TW M K GL KSIG+SNFN+ Q++ I++ GL+ K
Sbjct: 128 EELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYK 187
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + + +L FC+ DIV++AY+ GS
Sbjct: 188 PVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGS 223
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 154 bits (373), Expect = 5e-37
Identities = 89/216 (41%), Positives = 128/216 (59%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN 516
K ++G +KRE IF T+KLW+++H E V PAL SL+ L+YVDLYLIH P+++
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPG 125
Query: 517 DTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
+ L D VD TW M K GL KSIG+SNFN+ Q++ I++ GL+ K
Sbjct: 126 EELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + + +L FC+ DIV++AY+ GS
Sbjct: 186 PVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGS 221
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 154 bits (373), Expect = 5e-37
Identities = 89/216 (41%), Positives = 128/216 (59%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN 516
K ++G +KRE IF T+KLW+++H E V PAL SL+ L+YVDLYLIH P+++
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPG 125
Query: 517 DTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
+ L D VD TW M K GL KSIG+SNFN+ Q++ I++ GL+ K
Sbjct: 126 EELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + + +L FC+ DIV++AY+ GS
Sbjct: 186 PVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGS 221
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 154 bits (373), Expect = 5e-37
Identities = 89/216 (41%), Positives = 128/216 (59%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN 516
K ++G +KRE IF T+KLW+++H E V PAL SL+ L+YVDLYLIH P+++
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPG 125
Query: 517 DTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
+ L D VD TW M K GL KSIG+SNFN+ Q++ I++ GL+ K
Sbjct: 126 EELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + + +L FC+ DIV++AY+ GS
Sbjct: 186 PVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGS 221
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 154 bits (373), Expect = 5e-37
Identities = 89/216 (41%), Positives = 128/216 (59%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN 516
K ++G +KRE IF T+KLW+++H E V PAL SL+ L+YVDLYLIH P+++
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPG 125
Query: 517 DTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
+ L D VD TW M K GL KSIG+SNFN+ Q++ I++ GL+ K
Sbjct: 126 EELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + + +L FC+ DIV++AY+ GS
Sbjct: 186 PVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGS 221
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 154 bits (373), Expect = 5e-37
Identities = 89/216 (41%), Positives = 128/216 (59%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN 516
K ++G +KRE IF T+KLW+++H E V PAL SL+ L+YVDLYLIH P+++
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPG 125
Query: 517 DTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
+ L D VD TW M K GL KSIG+SNFN+ Q++ I++ GL+ K
Sbjct: 126 EELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + + +L FC+ DIV++AY+ GS
Sbjct: 186 PVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGS 221
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 154 bits (373), Expect = 5e-37
Identities = 89/216 (41%), Positives = 128/216 (59%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN 516
K ++G +KRE IF T+KLW+++H E V PAL SL+ L+YVDLYLIH P+++
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPG 125
Query: 517 DTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
+ L D VD TW M K GL KSIG+SNFN+ Q++ I++ GL+ K
Sbjct: 126 EELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + + +L FC+ DIV++AY+ GS
Sbjct: 186 PVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGS 221
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 153 bits (372), Expect = 6e-37
Identities = 87/212 (41%), Positives = 128/212 (60%), Gaps = 14/212 (6%)
Frame = +1
Query: 175 PVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF 351
PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+QVG A+ K
Sbjct: 2 PVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQVGLAIRSKI 54
Query: 352 SEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDT-- 522
++G +KRE IF T+KLW ++ + + V PAL SL+ L L+YVDLYL+H+P+A+ +T
Sbjct: 55 ADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPL 114
Query: 523 --------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSAL 672
+ D VD TW M K GL KSIG+SNFN Q++ I++ GL+ KP
Sbjct: 115 PKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCN 174
Query: 673 QIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
Q+E + L Q +L FC+ DIV++A++ G+
Sbjct: 175 QVECHPYLNQSKLLDFCKSKDIVLVAHSALGT 206
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 153 bits (372), Expect = 6e-37
Identities = 101/254 (39%), Positives = 142/254 (55%), Gaps = 15/254 (5%)
Frame = +1
Query: 163 GGHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALT 342
G P++ LGTW P G+V + AV A++ GY HID A+ Y E++VG A+
Sbjct: 10 GAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 343 KKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA----- 504
+K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWPI
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPIGFKPGK 120
Query: 505 -MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KP 663
F D + + + LDTW M + GL K+IGISNFN Q++ I++ GL+ KP
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 664 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFR--ASSTRRSSAED*R*TXRRYR 837
+ QIE + L Q +L ++C+ IVV AY+P GS R A S ED R +
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPR--IKAIA 238
Query: 838 PKIQQNVPQVALRF 879
K + QV +RF
Sbjct: 239 AKHNKTTAQVLIRF 252
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 153 bits (370), Expect = 1e-36
Identities = 87/218 (39%), Positives = 120/218 (55%), Gaps = 12/218 (5%)
Frame = +1
Query: 163 GGHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALT 342
G P++ LGTW K + QV + AV YAL GY HID A YG E ++G AL
Sbjct: 11 GQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGEALK 61
Query: 343 KKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN 516
+ G + RE +F+T+KLWN+ H E V PALRK+L +L LEY+DLYL+HWP A
Sbjct: 62 EDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG 121
Query: 517 DT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPS 666
D D+ + +TW+ + GL +++G+SNFN QI I+ +P+
Sbjct: 122 DNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPA 181
Query: 667 ALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFRA 780
LQ+E + L Q EL C+ + V AY+P GS RA
Sbjct: 182 VLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRA 219
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 153 bits (370), Expect = 1e-36
Identities = 87/218 (39%), Positives = 120/218 (55%), Gaps = 12/218 (5%)
Frame = +1
Query: 163 GGHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALT 342
G P++ LGTW K + QV + AV YAL GY HID A YG E ++G AL
Sbjct: 11 GQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGEALK 61
Query: 343 KKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN 516
+ G + RE +F+T+KLWN+ H E V PALRK+L +L LEY+DLYL+HWP A
Sbjct: 62 EDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG 121
Query: 517 DT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPS 666
D D+ + +TW+ + GL +++G+SNFN QI I+ +P+
Sbjct: 122 DNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPA 181
Query: 667 ALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFRA 780
LQ+E + L Q EL C+ + V AY+P GS RA
Sbjct: 182 VLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRA 219
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 153 bits (370), Expect = 1e-36
Identities = 87/218 (39%), Positives = 120/218 (55%), Gaps = 12/218 (5%)
Frame = +1
Query: 163 GGHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALT 342
G P++ LGTW K + QV + AV YAL GY HID A YG E ++G AL
Sbjct: 11 GQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGEALK 61
Query: 343 KKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN 516
+ G + RE +F+T+KLWN+ H E V PALRK+L +L LEY+DLYL+HWP A
Sbjct: 62 EDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG 121
Query: 517 DT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPS 666
D D+ + +TW+ + GL +++G+SNFN QI I+ +P+
Sbjct: 122 DNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPA 181
Query: 667 ALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFRA 780
LQ+E + L Q EL C+ + V AY+P GS RA
Sbjct: 182 VLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRA 219
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 153 bits (370), Expect = 1e-36
Identities = 87/218 (39%), Positives = 120/218 (55%), Gaps = 12/218 (5%)
Frame = +1
Query: 163 GGHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALT 342
G P++ LGTW K + QV + AV YAL GY HID A YG E ++G AL
Sbjct: 11 GQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGEALK 61
Query: 343 KKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN 516
+ G + RE +F+T+KLWN+ H E V PALRK+L +L LEY+DLYL+HWP A
Sbjct: 62 EDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG 121
Query: 517 DT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPS 666
D D+ + +TW+ + GL +++G+SNFN QI I+ +P+
Sbjct: 122 DNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPA 181
Query: 667 ALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFRA 780
LQ+E + L Q EL C+ + V AY+P GS RA
Sbjct: 182 VLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRA 219
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 153 bits (370), Expect = 1e-36
Identities = 87/218 (39%), Positives = 120/218 (55%), Gaps = 12/218 (5%)
Frame = +1
Query: 163 GGHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALT 342
G P++ LGTW K + QV + AV YAL GY HID A YG E ++G AL
Sbjct: 11 GQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGEALK 61
Query: 343 KKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN 516
+ G + RE +F+T+KLWN+ H E V PALRK+L +L LEY+DLYL+HWP A
Sbjct: 62 EDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG 121
Query: 517 DT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPS 666
D D+ + +TW+ + GL +++G+SNFN QI I+ +P+
Sbjct: 122 DNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPA 181
Query: 667 ALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFRA 780
LQ+E + L Q EL C+ + V AY+P GS RA
Sbjct: 182 VLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRA 219
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 153 bits (370), Expect = 1e-36
Identities = 87/218 (39%), Positives = 120/218 (55%), Gaps = 12/218 (5%)
Frame = +1
Query: 163 GGHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALT 342
G P++ LGTW K + QV + AV YAL GY HID A YG E ++G AL
Sbjct: 11 GQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGEALK 61
Query: 343 KKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN 516
+ G + RE +F+T+KLWN+ H E V PALRK+L +L LEY+DLYL+HWP A
Sbjct: 62 EDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG 121
Query: 517 DT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPS 666
D D+ + +TW+ + GL +++G+SNFN QI I+ +P+
Sbjct: 122 DNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPA 181
Query: 667 ALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFRA 780
LQ+E + L Q EL C+ + V AY+P GS RA
Sbjct: 182 VLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRA 219
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 153 bits (370), Expect = 1e-36
Identities = 87/218 (39%), Positives = 120/218 (55%), Gaps = 12/218 (5%)
Frame = +1
Query: 163 GGHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALT 342
G P++ LGTW K + QV + AV YAL GY HID A YG E ++G AL
Sbjct: 11 GQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGEALK 61
Query: 343 KKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN 516
+ G + RE +F+T+KLWN+ H E V PALRK+L +L LEY+DLYL+HWP A
Sbjct: 62 EDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG 121
Query: 517 DT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPS 666
D D+ + +TW+ + GL +++G+SNFN QI I+ +P+
Sbjct: 122 DNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPA 181
Query: 667 ALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFRA 780
LQ+E + L Q EL C+ + V AY+P GS RA
Sbjct: 182 VLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRA 219
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 153 bits (370), Expect = 1e-36
Identities = 87/218 (39%), Positives = 120/218 (55%), Gaps = 12/218 (5%)
Frame = +1
Query: 163 GGHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALT 342
G P++ LGTW K + QV + AV YAL GY HID A YG E ++G AL
Sbjct: 11 GQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGEALK 61
Query: 343 KKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN 516
+ G + RE +F+T+KLWN+ H E V PALRK+L +L LEY+DLYL+HWP A
Sbjct: 62 EDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG 121
Query: 517 DT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPS 666
D D+ + +TW+ + GL +++G+SNFN QI I+ +P+
Sbjct: 122 DNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPA 181
Query: 667 ALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFRA 780
LQ+E + L Q EL C+ + V AY+P GS RA
Sbjct: 182 VLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRA 219
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 152 bits (369), Expect = 1e-36
Identities = 91/217 (41%), Positives = 129/217 (59%), Gaps = 15/217 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+QVG A+
Sbjct: 10 GHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQVGLAI 62
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--- 507
K ++G +KRE IF T+KLW + H E PAL +SL+NL L+YVDLYLIH+P+++
Sbjct: 63 RSKIADGSVKREDIFYTSKLWCNSHRPELDRPALERSLKNLQLDYVDLYLIHFPVSVKPG 122
Query: 508 ------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
EN +L D VD TW + K L KSIG+SNFN+ ++ I++ GL+ K
Sbjct: 123 EEVIPKDENGKILFDTVDLCATWEAVEKCKDAELAKSIGVSNFNRSTLEMILNKPGLQVK 182
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSL 771
P Q+E + Q +L FC+ DIV++AY+ GSL
Sbjct: 183 PVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSL 219
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 151 bits (367), Expect = 3e-36
Identities = 100/254 (39%), Positives = 141/254 (55%), Gaps = 15/254 (5%)
Frame = +1
Query: 163 GGHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALT 342
G P++ LGTW P G+V + AV A++ GY HID A+ Y E++VG A+
Sbjct: 10 GAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 343 KKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA----- 504
+K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 505 -MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KP 663
F D + + + LDTW M + GL K+IGISNFN Q++ I++ GL+ KP
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 664 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFR--ASSTRRSSAED*R*TXRRYR 837
+ QIE + L Q +L ++C+ IVV AY+P GS R A S ED R +
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPR--IKAIA 238
Query: 838 PKIQQNVPQVALRF 879
K + QV +RF
Sbjct: 239 AKHNKTTAQVLIRF 252
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 151 bits (367), Expect = 3e-36
Identities = 88/216 (40%), Positives = 128/216 (59%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN 516
K ++G ++RE IF T+KLW+++H E V PAL SL+ L+YVDLYLIH P+++
Sbjct: 66 RSKIADGSVEREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPG 125
Query: 517 DTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
+ L D VD TW M K GL KSIG+SNFN+ Q++ I++ GL+ K
Sbjct: 126 EELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + + +L FC+ DIV++AY+ GS
Sbjct: 186 PVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGS 221
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 151 bits (367), Expect = 3e-36
Identities = 100/254 (39%), Positives = 141/254 (55%), Gaps = 15/254 (5%)
Frame = +1
Query: 163 GGHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALT 342
G P++ LGTW P G+V + AV A++ GY HID A+ Y E++VG A+
Sbjct: 10 GAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 343 KKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA----- 504
+K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 505 -MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KP 663
F D + + + LDTW M + GL K+IGISNFN Q++ I++ GL+ KP
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 664 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFR--ASSTRRSSAED*R*TXRRYR 837
+ QIE + L Q +L ++C+ IVV AY+P GS R A S ED R +
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPR--IKAIA 238
Query: 838 PKIQQNVPQVALRF 879
K + QV +RF
Sbjct: 239 AKHNKTTAQVLIRF 252
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 151 bits (367), Expect = 3e-36
Identities = 100/254 (39%), Positives = 141/254 (55%), Gaps = 15/254 (5%)
Frame = +1
Query: 163 GGHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALT 342
G P++ LGTW P G+V + AV A++ GY HID A+ Y E++VG A+
Sbjct: 10 GAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 343 KKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA----- 504
+K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 505 -MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KP 663
F D + + + LDTW M + GL K+IGISNFN Q++ I++ GL+ KP
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 664 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFR--ASSTRRSSAED*R*TXRRYR 837
+ QIE + L Q +L ++C+ IVV AY+P GS R A S ED R +
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPR--IKAIA 238
Query: 838 PKIQQNVPQVALRF 879
K + QV +RF
Sbjct: 239 AKHNKTTAQVLIRF 252
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 151 bits (367), Expect = 3e-36
Identities = 100/254 (39%), Positives = 141/254 (55%), Gaps = 15/254 (5%)
Frame = +1
Query: 163 GGHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALT 342
G P++ LGTW P G+V + AV A++ GY HID A+ Y E++VG A+
Sbjct: 10 GAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 343 KKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA----- 504
+K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 505 -MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KP 663
F D + + + LDTW M + GL K+IGISNFN Q++ I++ GL+ KP
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 664 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFR--ASSTRRSSAED*R*TXRRYR 837
+ QIE + L Q +L ++C+ IVV AY+P GS R A S ED R +
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPR--IKAIA 238
Query: 838 PKIQQNVPQVALRF 879
K + QV +RF
Sbjct: 239 AKHNKTTAQVLIRF 252
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 151 bits (367), Expect = 3e-36
Identities = 100/254 (39%), Positives = 141/254 (55%), Gaps = 15/254 (5%)
Frame = +1
Query: 163 GGHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALT 342
G P++ LGTW P G+V + AV A++ GY HID A+ Y E++VG A+
Sbjct: 10 GAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 343 KKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA----- 504
+K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 505 -MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KP 663
F D + + + LDTW M + GL K+IGISNFN Q++ I++ GL+ KP
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 664 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFR--ASSTRRSSAED*R*TXRRYR 837
+ QIE + L Q +L ++C+ IVV AY+P GS R A S ED R +
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPR--IKAIA 238
Query: 838 PKIQQNVPQVALRF 879
K + QV +RF
Sbjct: 239 AKHNKTTAQVLIRF 252
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 151 bits (367), Expect = 3e-36
Identities = 100/254 (39%), Positives = 141/254 (55%), Gaps = 15/254 (5%)
Frame = +1
Query: 163 GGHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALT 342
G P++ LGTW P G+V + AV A++ GY HID A+ Y E++VG A+
Sbjct: 10 GAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 343 KKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA----- 504
+K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 505 -MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KP 663
F D + + + LDTW M + GL K+IGISNFN Q++ I++ GL+ KP
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 664 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFR--ASSTRRSSAED*R*TXRRYR 837
+ QIE + L Q +L ++C+ IVV AY+P GS R A S ED R +
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPR--IKAIA 238
Query: 838 PKIQQNVPQVALRF 879
K + QV +RF
Sbjct: 239 AKHNKTTAQVLIRF 252
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 151 bits (367), Expect = 3e-36
Identities = 100/254 (39%), Positives = 141/254 (55%), Gaps = 15/254 (5%)
Frame = +1
Query: 163 GGHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALT 342
G P++ LGTW P G+V + AV A++ GY HID A+ Y E++VG A+
Sbjct: 10 GAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 343 KKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA----- 504
+K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 505 -MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KP 663
F D + + + LDTW M + GL K+IGISNFN Q++ I++ GL+ KP
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 664 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFR--ASSTRRSSAED*R*TXRRYR 837
+ QIE + L Q +L ++C+ IVV AY+P GS R A S ED R +
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPR--IKAIA 238
Query: 838 PKIQQNVPQVALRF 879
K + QV +RF
Sbjct: 239 AKHNKTTAQVLIRF 252
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 151 bits (367), Expect = 3e-36
Identities = 100/254 (39%), Positives = 141/254 (55%), Gaps = 15/254 (5%)
Frame = +1
Query: 163 GGHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALT 342
G P++ LGTW P G+V + AV A++ GY HID A+ Y E++VG A+
Sbjct: 10 GAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 343 KKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA----- 504
+K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 505 -MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KP 663
F D + + + LDTW M + GL K+IGISNFN Q++ I++ GL+ KP
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 664 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFR--ASSTRRSSAED*R*TXRRYR 837
+ QIE + L Q +L ++C+ IVV AY+P GS R A S ED R +
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPR--IKAIA 238
Query: 838 PKIQQNVPQVALRF 879
K + QV +RF
Sbjct: 239 AKHNKTTAQVLIRF 252
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 151 bits (367), Expect = 3e-36
Identities = 100/254 (39%), Positives = 141/254 (55%), Gaps = 15/254 (5%)
Frame = +1
Query: 163 GGHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALT 342
G P++ LGTW P G+V + AV A++ GY HID A+ Y E++VG A+
Sbjct: 10 GAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 343 KKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA----- 504
+K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 505 -MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KP 663
F D + + + LDTW M + GL K+IGISNFN Q++ I++ GL+ KP
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 664 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFR--ASSTRRSSAED*R*TXRRYR 837
+ QIE + L Q +L ++C+ IVV AY+P GS R A S ED R +
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPR--IKAIA 238
Query: 838 PKIQQNVPQVALRF 879
K + QV +RF
Sbjct: 239 AKHNKTTAQVLIRF 252
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 151 bits (367), Expect = 3e-36
Identities = 100/254 (39%), Positives = 141/254 (55%), Gaps = 15/254 (5%)
Frame = +1
Query: 163 GGHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALT 342
G P++ LGTW P G+V + AV A++ GY HID A+ Y E++VG A+
Sbjct: 10 GAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 343 KKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA----- 504
+K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 505 -MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KP 663
F D + + + LDTW M + GL K+IGISNFN Q++ I++ GL+ KP
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 664 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFR--ASSTRRSSAED*R*TXRRYR 837
+ QIE + L Q +L ++C+ IVV AY+P GS R A S ED R +
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPR--IKAIA 238
Query: 838 PKIQQNVPQVALRF 879
K + QV +RF
Sbjct: 239 AKHNKTTAQVLIRF 252
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 151 bits (367), Expect = 3e-36
Identities = 100/254 (39%), Positives = 141/254 (55%), Gaps = 15/254 (5%)
Frame = +1
Query: 163 GGHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALT 342
G P++ LGTW P G+V + AV A++ GY HID A+ Y E++VG A+
Sbjct: 10 GAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 343 KKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA----- 504
+K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 505 -MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KP 663
F D + + + LDTW M + GL K+IGISNFN Q++ I++ GL+ KP
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 664 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFR--ASSTRRSSAED*R*TXRRYR 837
+ QIE + L Q +L ++C+ IVV AY+P GS R A S ED R +
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPR--IKAIA 238
Query: 838 PKIQQNVPQVALRF 879
K + QV +RF
Sbjct: 239 AKHNKTTAQVLIRF 252
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 151 bits (366), Expect = 3e-36
Identities = 100/254 (39%), Positives = 140/254 (55%), Gaps = 15/254 (5%)
Frame = +1
Query: 163 GGHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALT 342
G P++ LGTW P G+V + AV A++ GY HID A+ Y E++VG A+
Sbjct: 10 GAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 343 KKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA----- 504
+K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFRPGK 120
Query: 505 -MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KP 663
F D + + + LDTW M + GL K+IGISNFN Q++ I+ GL+ KP
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILSKPGLKYKP 180
Query: 664 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFR--ASSTRRSSAED*R*TXRRYR 837
+ QIE + L Q +L ++C+ IVV AY+P GS R A S ED R +
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPR--IKAIA 238
Query: 838 PKIQQNVPQVALRF 879
K + QV +RF
Sbjct: 239 AKHNKTTAQVLIRF 252
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 151 bits (365), Expect = 4e-36
Identities = 96/250 (38%), Positives = 136/250 (54%), Gaps = 15/250 (6%)
Frame = +1
Query: 175 PVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFS 354
P+V LGTW P GKV ++AV A++AGY HID AY Y E +VG A+ +K
Sbjct: 14 PIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQ 64
Query: 355 E-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLD 531
E +KRE +FI +KLW ++ ER V A K+L++L L Y+D+YLIHWP D L
Sbjct: 65 EKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFP 124
Query: 532 NVD----------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQ 675
D FLD W M + GL K++G+SNF+ QI+++++ GL+ KP Q
Sbjct: 125 KDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQ 184
Query: 676 IELNLNLQQPELFKFCRENDIVVMAYTPFGSLFR--ASSTRRSSAED*R*TXRRYRPKIQ 849
+E + L Q +L ++C I V AY+P GS R A S ED + + K +
Sbjct: 185 VECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPK--IKEIAAKHK 242
Query: 850 QNVPQVALRF 879
+ QV +RF
Sbjct: 243 KTAAQVLIRF 252
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 151 bits (365), Expect = 4e-36
Identities = 88/216 (40%), Positives = 127/216 (58%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN 516
K ++G + RE IF T+KLW+++H E V PAL SL+ L+YVDLYLIH P+++
Sbjct: 66 RSKIADGSVMREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPG 125
Query: 517 DTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
+ L D VD TW M K GL KSIG+SNFN+ Q++ I++ GL+ K
Sbjct: 126 EELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + + +L FC+ DIV++AY+ GS
Sbjct: 186 PVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGS 221
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 151 bits (365), Expect = 4e-36
Identities = 89/216 (41%), Positives = 126/216 (58%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQVGLAV 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN 516
K ++G +KRE IF T+KLW + H E V PAL +SL+ L+YVDLYLIH P+++
Sbjct: 66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKKAQLDYVDLYLIHSPMSLKPG 125
Query: 517 DTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
+ L D VD TW M K GL KSIG+SNFN+ Q++ I++ GL+ K
Sbjct: 126 EELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + + +L FC+ DIV++AY+ GS
Sbjct: 186 PVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGS 221
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 151 bits (365), Expect = 4e-36
Identities = 96/250 (38%), Positives = 136/250 (54%), Gaps = 15/250 (6%)
Frame = +1
Query: 175 PVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFS 354
P+V LGTW P GKV ++AV A++AGY HID AY Y E +VG A+ +K
Sbjct: 14 PIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQ 64
Query: 355 E-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLD 531
E +KRE +FI +KLW ++ ER V A K+L++L L Y+D+YLIHWP D L
Sbjct: 65 EKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFP 124
Query: 532 NVD----------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQ 675
D FLD W M + GL K++G+SNF+ QI+++++ GL+ KP Q
Sbjct: 125 KDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQ 184
Query: 676 IELNLNLQQPELFKFCRENDIVVMAYTPFGSLFR--ASSTRRSSAED*R*TXRRYRPKIQ 849
+E + L Q +L ++C I V AY+P GS R A S ED + + K +
Sbjct: 185 VECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPK--IKEIAAKHK 242
Query: 850 QNVPQVALRF 879
+ QV +RF
Sbjct: 243 KTAAQVLIRF 252
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 151 bits (365), Expect = 4e-36
Identities = 96/250 (38%), Positives = 136/250 (54%), Gaps = 15/250 (6%)
Frame = +1
Query: 175 PVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFS 354
P+V LGTW P GKV ++AV A++AGY HID AY Y E +VG A+ +K
Sbjct: 14 PIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQ 64
Query: 355 E-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLD 531
E +KRE +FI +KLW ++ ER V A K+L++L L Y+D+YLIHWP D L
Sbjct: 65 EKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFP 124
Query: 532 NVD----------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQ 675
D FLD W M + GL K++G+SNF+ QI+++++ GL+ KP Q
Sbjct: 125 KDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQ 184
Query: 676 IELNLNLQQPELFKFCRENDIVVMAYTPFGSLFR--ASSTRRSSAED*R*TXRRYRPKIQ 849
+E + L Q +L ++C I V AY+P GS R A S ED + + K +
Sbjct: 185 VECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPK--IKEIAAKHK 242
Query: 850 QNVPQVALRF 879
+ QV +RF
Sbjct: 243 KTAAQVLIRF 252
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 151 bits (365), Expect = 4e-36
Identities = 96/250 (38%), Positives = 136/250 (54%), Gaps = 15/250 (6%)
Frame = +1
Query: 175 PVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFS 354
P+V LGTW P GKV ++AV A++AGY HID AY Y E +VG A+ +K
Sbjct: 14 PIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQ 64
Query: 355 E-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLD 531
E +KRE +FI +KLW ++ ER V A K+L++L L Y+D+YLIHWP D L
Sbjct: 65 EKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFP 124
Query: 532 NVD----------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQ 675
D FLD W M + GL K++G+SNF+ QI+++++ GL+ KP Q
Sbjct: 125 KDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQ 184
Query: 676 IELNLNLQQPELFKFCRENDIVVMAYTPFGSLFR--ASSTRRSSAED*R*TXRRYRPKIQ 849
+E + L Q +L ++C I V AY+P GS R A S ED + + K +
Sbjct: 185 VECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPK--IKEIAAKHK 242
Query: 850 QNVPQVALRF 879
+ QV +RF
Sbjct: 243 KTAAQVLIRF 252
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 151 bits (365), Expect = 4e-36
Identities = 96/250 (38%), Positives = 136/250 (54%), Gaps = 15/250 (6%)
Frame = +1
Query: 175 PVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFS 354
P+V LGTW P GKV ++AV A++AGY HID AY Y E +VG A+ +K
Sbjct: 14 PIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQ 64
Query: 355 E-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLD 531
E +KRE +FI +KLW ++ ER V A K+L++L L Y+D+YLIHWP D L
Sbjct: 65 EKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFP 124
Query: 532 NVD----------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQ 675
D FLD W M + GL K++G+SNF+ QI+++++ GL+ KP Q
Sbjct: 125 KDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQ 184
Query: 676 IELNLNLQQPELFKFCRENDIVVMAYTPFGSLFR--ASSTRRSSAED*R*TXRRYRPKIQ 849
+E + L Q +L ++C I V AY+P GS R A S ED + + K +
Sbjct: 185 VECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPK--IKEIAAKHK 242
Query: 850 QNVPQVALRF 879
+ QV +RF
Sbjct: 243 KTAAQVLIRF 252
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 150 bits (364), Expect = 6e-36
Identities = 88/216 (40%), Positives = 127/216 (58%), Gaps = 15/216 (6%)
Frame = +1
Query: 166 GHX-PVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
GH PV+ GT+ P+ K ++V+ A+EAG+ HID+A+ Y E+QVG A+
Sbjct: 13 GHFMPVLGFGTYAPPEVPRSKALEVSK-------LAIEAGFRHIDSAHLYNNEEQVGLAI 65
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN 516
K ++G +KRE IF T+KLW++ H E V PAL SL+ L+YVDLYLIH P+++
Sbjct: 66 RSKIADGSVKREDIFYTSKLWSTSHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPG 125
Query: 517 DTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-K 660
+ L D VD TW M K GL KSIG+SNFN+ Q++ I++ GL+ K
Sbjct: 126 EELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYK 185
Query: 661 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
P Q+E + + +L FC+ DIV++AY+ GS
Sbjct: 186 PVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGS 221
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 150 bits (363), Expect = 8e-36
Identities = 89/215 (41%), Positives = 127/215 (59%), Gaps = 13/215 (6%)
Frame = +1
Query: 163 GGHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALT 342
G P++ LGTW P G+V + AV A++ GY HID A+ Y E++VG A+
Sbjct: 7 GAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 57
Query: 343 KKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA----- 504
+K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 58 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 117
Query: 505 -MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KP 663
F D + + + LDTW M + GL K+IGISNFN Q++ I++ GL+ KP
Sbjct: 118 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 177
Query: 664 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
+ QIE + L Q +L ++C+ IVV AY+P GS
Sbjct: 178 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGS 212
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 148 bits (358), Expect = 3e-35
Identities = 95/250 (38%), Positives = 135/250 (54%), Gaps = 15/250 (6%)
Frame = +1
Query: 175 PVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFS 354
P+V LGTW P GKV ++AV A++AGY HID AY Y E +VG A+ +K
Sbjct: 14 PIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQ 64
Query: 355 E-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLD 531
E +KRE +FI +KLW ++ ER V A K+L++ L Y+D+YLIHWP D L
Sbjct: 65 EKAVKREDLFIASKLWPTFFERPLVRKAFEKTLKDPKLSYLDVYLIHWPQGFKSGDDLFP 124
Query: 532 NVD----------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQ 675
D FLD W M + GL K++G+SNF+ QI+++++ GL+ KP Q
Sbjct: 125 KDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQ 184
Query: 676 IELNLNLQQPELFKFCRENDIVVMAYTPFGSLFR--ASSTRRSSAED*R*TXRRYRPKIQ 849
+E + L Q +L ++C I V AY+P GS R A S ED + + K +
Sbjct: 185 VECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPK--IKEIAAKHK 242
Query: 850 QNVPQVALRF 879
+ QV +RF
Sbjct: 243 KTAAQVLIRF 252
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 91.9 bits (218), Expect(2) = 5e-35
Identities = 51/113 (45%), Positives = 66/113 (58%), Gaps = 1/113 (0%)
Frame = +1
Query: 166 GHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 345
G P V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 346 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 501
K EG ++RE +FI TKLW + H++ V A RKSL+ L L Y+DLYLIHWP+
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105
Score = 77.0 bits (181), Expect(2) = 5e-35
Identities = 39/86 (45%), Positives = 51/86 (59%), Gaps = 2/86 (2%)
Frame = +1
Query: 514 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIELN 687
N + + DFLDTW M D GL K+IG+SNFN EQ++R+++ GL KP QIE +
Sbjct: 139 NMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECH 198
Query: 688 LNLQQPELFKFCRENDIVVMAYTPFG 765
L Q L FC+ D+ V AY P G
Sbjct: 199 PYLTQKNLISFCQSRDVSVTAYRPLG 224
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 91.9 bits (218), Expect(2) = 5e-35
Identities = 51/113 (45%), Positives = 66/113 (58%), Gaps = 1/113 (0%)
Frame = +1
Query: 166 GHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 345
G P V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 346 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 501
K EG ++RE +FI TKLW + H++ V A RKSL+ L L Y+DLYLIHWP+
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105
Score = 77.0 bits (181), Expect(2) = 5e-35
Identities = 39/86 (45%), Positives = 51/86 (59%), Gaps = 2/86 (2%)
Frame = +1
Query: 514 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIELN 687
N + + DFLDTW M D GL K+IG+SNFN EQ++R+++ GL KP QIE +
Sbjct: 139 NMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECH 198
Query: 688 LNLQQPELFKFCRENDIVVMAYTPFG 765
L Q L FC+ D+ V AY P G
Sbjct: 199 PYLTQKNLISFCQSRDVSVTAYRPLG 224
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 91.9 bits (218), Expect(2) = 5e-35
Identities = 51/113 (45%), Positives = 66/113 (58%), Gaps = 1/113 (0%)
Frame = +1
Query: 166 GHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 345
G P V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 346 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 501
K EG ++RE +FI TKLW + H++ V A RKSL+ L L Y+DLYLIHWP+
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105
Score = 77.0 bits (181), Expect(2) = 5e-35
Identities = 39/86 (45%), Positives = 51/86 (59%), Gaps = 2/86 (2%)
Frame = +1
Query: 514 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIELN 687
N + + DFLDTW M D GL K+IG+SNFN EQ++R+++ GL KP QIE +
Sbjct: 139 NMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECH 198
Query: 688 LNLQQPELFKFCRENDIVVMAYTPFG 765
L Q L FC+ D+ V AY P G
Sbjct: 199 PYLTQKNLISFCQSRDVSVTAYRPLG 224
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 146 bits (353), Expect = 1e-34
Identities = 99/254 (38%), Positives = 140/254 (55%), Gaps = 15/254 (5%)
Frame = +1
Query: 163 GGHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALT 342
G P++ LGTW P G+V + AV A++ GY HID A+ Y E++VG A+
Sbjct: 10 GAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 343 KKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA----- 504
+K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 505 -MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KP 663
F D + + + LDT M + GL K+IGISNFN Q++ I++ GL+ KP
Sbjct: 121 EFFPLDESGNVVPSDTNILDTRAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 664 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFR--ASSTRRSSAED*R*TXRRYR 837
+ QIE + L Q +L ++C+ IVV AY+P GS R A S ED R +
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPR--IKAIA 238
Query: 838 PKIQQNVPQVALRF 879
K + QV +RF
Sbjct: 239 AKHNKTTAQVLIRF 252
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 142 bits (344), Expect = 2e-33
Identities = 84/215 (39%), Positives = 124/215 (57%), Gaps = 13/215 (6%)
Frame = +1
Query: 163 GGHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALT 342
G P++ LGT+ + K T+ V A++ GY HID AY Y E +VG A+
Sbjct: 15 GNSIPIIGLGTYSEPKSTPKGACATS-----VKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69
Query: 343 KKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEND 519
+K +EG ++RE IF KLW + H E V P L ++L L L+YVDLY+I P+A D
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129
Query: 520 TLL---DNVDFL-------DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KP 663
+ +N +L TW M K GL KS+G+SNFN+ Q++ I++ GL+ KP
Sbjct: 130 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKP 189
Query: 664 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
+ Q+E + QP+L KFC+++DIV+ AY+P G+
Sbjct: 190 VSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGT 224
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 142 bits (344), Expect = 2e-33
Identities = 84/215 (39%), Positives = 124/215 (57%), Gaps = 13/215 (6%)
Frame = +1
Query: 163 GGHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALT 342
G P++ LGT+ + K T+ V A++ GY HID AY Y E +VG A+
Sbjct: 15 GNSIPIIGLGTYSEPKSTPKGACATS-----VKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69
Query: 343 KKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEND 519
+K +EG ++RE IF KLW + H E V P L ++L L L+YVDLY+I P+A D
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129
Query: 520 TLL---DNVDFL-------DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KP 663
+ +N +L TW M K GL KS+G+SNFN+ Q++ I++ GL+ KP
Sbjct: 130 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKP 189
Query: 664 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
+ Q+E + QP+L KFC+++DIV+ AY+P G+
Sbjct: 190 VSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGT 224
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 142 bits (344), Expect = 2e-33
Identities = 84/215 (39%), Positives = 124/215 (57%), Gaps = 13/215 (6%)
Frame = +1
Query: 163 GGHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALT 342
G P++ LGT+ + K T+ V A++ GY HID AY Y E +VG A+
Sbjct: 15 GNSIPIIGLGTYSEPKSTPKGACATS-----VKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69
Query: 343 KKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEND 519
+K +EG ++RE IF KLW + H E V P L ++L L L+YVDLY+I P+A D
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129
Query: 520 TLL---DNVDFL-------DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KP 663
+ +N +L TW M K GL KS+G+SNFN+ Q++ I++ GL+ KP
Sbjct: 130 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKP 189
Query: 664 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
+ Q+E + QP+L KFC+++DIV+ AY+P G+
Sbjct: 190 VSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGT 224
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 142 bits (344), Expect = 2e-33
Identities = 84/215 (39%), Positives = 124/215 (57%), Gaps = 13/215 (6%)
Frame = +1
Query: 163 GGHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALT 342
G P++ LGT+ + K T+ V A++ GY HID AY Y E +VG A+
Sbjct: 15 GNSIPIIGLGTYSEPKSTPKGACATS-----VKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69
Query: 343 KKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEND 519
+K +EG ++RE IF KLW + H E V P L ++L L L+YVDLY+I P+A D
Sbjct: 70 EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129
Query: 520 TLL---DNVDFL-------DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KP 663
+ +N +L TW M K GL KS+G+SNFN+ Q++ I++ GL+ KP
Sbjct: 130 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKP 189
Query: 664 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
+ Q+E + QP+L KFC+++DIV+ AY+P G+
Sbjct: 190 VSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGT 224
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 129 bits (312), Expect = 1e-29
Identities = 72/162 (44%), Positives = 102/162 (62%), Gaps = 13/162 (8%)
Frame = +1
Query: 322 QVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 498
+VG A+ K ++G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P
Sbjct: 26 EVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 85
Query: 499 IAM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS 648
+++ EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++
Sbjct: 86 VSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNK 145
Query: 649 -GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
GL+ KP Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 146 PGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGS 187
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 91.9 bits (218), Expect(2) = 1e-28
Identities = 51/113 (45%), Positives = 66/113 (58%), Gaps = 1/113 (0%)
Frame = +1
Query: 166 GHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 345
G P V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 346 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 501
K EG ++RE +FI TKLW + H++ V A RKSL+ L L Y+DLYLIHWP+
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105
Score = 55.6 bits (128), Expect(2) = 1e-28
Identities = 28/65 (43%), Positives = 40/65 (61%), Gaps = 2/65 (3%)
Frame = +1
Query: 514 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIELN 687
N + + DFLDTW M D GL K+IG+SNFN EQ++R+++ GL KP QI +
Sbjct: 139 NMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQILIR 198
Query: 688 LNLQQ 702
+Q+
Sbjct: 199 FQIQR 203
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 91.9 bits (218), Expect(2) = 1e-28
Identities = 51/113 (45%), Positives = 66/113 (58%), Gaps = 1/113 (0%)
Frame = +1
Query: 166 GHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 345
G P V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 346 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 501
K EG ++RE +FI TKLW + H++ V A RKSL+ L L Y+DLYLIHWP+
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105
Score = 55.6 bits (128), Expect(2) = 1e-28
Identities = 28/65 (43%), Positives = 40/65 (61%), Gaps = 2/65 (3%)
Frame = +1
Query: 514 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIELN 687
N + + DFLDTW M D GL K+IG+SNFN EQ++R+++ GL KP QI +
Sbjct: 139 NMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQILIR 198
Query: 688 LNLQQ 702
+Q+
Sbjct: 199 FQIQR 203
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 105 bits (253), Expect = 2e-22
Identities = 73/216 (33%), Positives = 111/216 (51%), Gaps = 14/216 (6%)
Frame = +1
Query: 163 GGHXPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
G PV+ GT+ H PK + + T A++ G+ HID+AY Y E++VG+A+
Sbjct: 16 GPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEEEVGQAI 68
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE- 513
+K ++G +KRE IF T KLW ++ E V PAL +SL+ L +YVDL++IH P AM +
Sbjct: 69 WEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKQP 128
Query: 514 ----------NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKP 663
+ +L+ V+ DTW + K GL KP
Sbjct: 129 GKELLPKDASGEIILETVELCDTWELELILNKPGLR---------------------YKP 167
Query: 664 SALQ-IELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
+ Q +E + L Q +L +FC+ DIV++AY+ GS
Sbjct: 168 TCNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALGS 203
>AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydela) protein.
Length = 147
Score = 105 bits (253), Expect = 2e-22
Identities = 57/121 (47%), Positives = 73/121 (60%), Gaps = 2/121 (1%)
Frame = +1
Query: 163 GGHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALT 342
G P++ LGTW K + QV + AV YAL GY HID A YG E ++G AL
Sbjct: 11 GQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGEALK 61
Query: 343 KKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN 516
+ G + RE +F+T+KLWN+ H E V PALRK+L +L LEY+DLYL+HWP A
Sbjct: 62 EDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG 121
Query: 517 D 519
D
Sbjct: 122 D 122
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 105 bits (253), Expect = 2e-22
Identities = 73/216 (33%), Positives = 111/216 (51%), Gaps = 14/216 (6%)
Frame = +1
Query: 163 GGHXPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
G PV+ GT+ H PK + + T A++ G+ HID+AY Y E++VG+A+
Sbjct: 16 GPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEEEVGQAI 68
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE- 513
+K ++G +KRE IF T KLW ++ E V PAL +SL+ L +YVDL++IH P AM +
Sbjct: 69 WEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKQP 128
Query: 514 ----------NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKP 663
+ +L+ V+ DTW + K GL KP
Sbjct: 129 GKELLPKDASGEIILETVELCDTWELELILNKPGLR---------------------YKP 167
Query: 664 SALQ-IELNLNLQQPELFKFCRENDIVVMAYTPFGS 768
+ Q +E + L Q +L +FC+ DIV++AY+ GS
Sbjct: 168 TCNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALGS 203
>BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 94.3 bits (224), Expect = 5e-19
Identities = 49/117 (41%), Positives = 72/117 (61%), Gaps = 2/117 (1%)
Frame = +1
Query: 163 GGHXPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
G PV+ GT+ H PK + + T A++ G+ HID+AY Y E++VG+A+
Sbjct: 16 GPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEEEVGQAI 68
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 507
+K ++G +KRE IF T KLW ++ E V PAL +SL+ L +YVDL++IH P AM
Sbjct: 69 WEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAM 125
>BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 94.3 bits (224), Expect = 5e-19
Identities = 49/117 (41%), Positives = 72/117 (61%), Gaps = 2/117 (1%)
Frame = +1
Query: 163 GGHXPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
G PV+ GT+ H PK + + T A++ G+ HID+AY Y E++VG+A+
Sbjct: 16 GPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEEEVGQAI 68
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 507
+K ++G +KRE IF T KLW ++ E V PAL +SL+ L +YVDL++IH P AM
Sbjct: 69 WEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAM 125
>AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ16347 fis, clone TESTI2036288, moderately
similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
Length = 129
Score = 94.3 bits (224), Expect = 5e-19
Identities = 49/117 (41%), Positives = 72/117 (61%), Gaps = 2/117 (1%)
Frame = +1
Query: 163 GGHXPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 339
G PV+ GT+ H PK + + T A++ G+ HID+AY Y E++VG+A+
Sbjct: 16 GPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEEEVGQAI 68
Query: 340 TKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 507
+K ++G +KRE IF T KLW ++ E V PAL +SL+ L +YVDL++IH P AM
Sbjct: 69 WEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAM 125
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 91.9 bits (218), Expect(2) = 2e-18
Identities = 51/113 (45%), Positives = 66/113 (58%), Gaps = 1/113 (0%)
Frame = +1
Query: 166 GHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 345
G P V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 346 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 501
K EG ++RE +FI TKLW + H++ V A RKSL+ L L Y+DLYLIHWP+
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105
Score = 21.4 bits (43), Expect(2) = 2e-18
Identities = 8/18 (44%), Positives = 11/18 (61%)
Frame = +1
Query: 514 NDTLLDNVDFLDTWRGMI 567
N + + DFLDTW +I
Sbjct: 139 NMVIPSDTDFLDTWEILI 156
>AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto
reductase protein.
Length = 130
Score = 87.0 bits (206), Expect = 8e-17
Identities = 45/116 (38%), Positives = 71/116 (61%), Gaps = 1/116 (0%)
Frame = +1
Query: 163 GGHXPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALT 342
G P++ GT + + V ++N E+AV A++ GY HID+AY + E+ +G+A+
Sbjct: 14 GKFMPILGFGTSVARK-----VAMSN-VEEAVQVAIDVGYRHIDSAYTHLNEEGIGQAIR 67
Query: 343 KKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 507
KK + G +KR+ IF TTK+W ++ E V L SL+ L L Y+DLYL H+P+ +
Sbjct: 68 KKIANGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVPL 123
>AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens
cDNA FLJ25413 fis, clone TST03402, highly similar to
3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ).
Length = 146
Score = 73.7 bits (173), Expect = 8e-13
Identities = 34/75 (45%), Positives = 52/75 (69%), Gaps = 2/75 (2%)
Frame = +1
Query: 550 TWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFC 723
TW M K GL KS+G+SNFN+ Q++ I++ GL+ KP + Q+E + QP+L KFC
Sbjct: 28 TWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFC 87
Query: 724 RENDIVVMAYTPFGS 768
+++DIV+ AY+P G+
Sbjct: 88 QQHDIVITAYSPLGT 102
>U33429-1|AAC50955.1| 367|Homo sapiens K+ channel beta 2 subunit
protein.
Length = 367
Score = 46.4 bits (105), Expect = 1e-04
Identities = 40/117 (34%), Positives = 57/117 (48%), Gaps = 11/117 (9%)
Frame = +1
Query: 181 VALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQVGRALTKK 348
+ LGTW+ Q+T++ EQ + A + G DTA Y E +G + KK
Sbjct: 52 LGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK 106
Query: 349 FSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYLIHWP 498
G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+ + P
Sbjct: 107 ---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP 160
>CR542287-1|CAG47082.1| 353|Homo sapiens KCNAB2 protein.
Length = 353
Score = 46.4 bits (105), Expect = 1e-04
Identities = 40/117 (34%), Positives = 57/117 (48%), Gaps = 11/117 (9%)
Frame = +1
Query: 181 VALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQVGRALTKK 348
+ LGTW+ Q+T++ EQ + A + G DTA Y E +G + KK
Sbjct: 38 LGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK 92
Query: 349 FSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYLIHWP 498
G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+ + P
Sbjct: 93 ---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP 146
>BC130413-1|AAI30414.1| 367|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 367
Score = 46.4 bits (105), Expect = 1e-04
Identities = 40/117 (34%), Positives = 57/117 (48%), Gaps = 11/117 (9%)
Frame = +1
Query: 181 VALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQVGRALTKK 348
+ LGTW+ Q+T++ EQ + A + G DTA Y E +G + KK
Sbjct: 52 LGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK 106
Query: 349 FSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYLIHWP 498
G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+ + P
Sbjct: 107 ---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP 160
>BC126424-1|AAI26425.1| 367|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 367
Score = 46.4 bits (105), Expect = 1e-04
Identities = 40/117 (34%), Positives = 57/117 (48%), Gaps = 11/117 (9%)
Frame = +1
Query: 181 VALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQVGRALTKK 348
+ LGTW+ Q+T++ EQ + A + G DTA Y E +G + KK
Sbjct: 52 LGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK 106
Query: 349 FSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYLIHWP 498
G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+ + P
Sbjct: 107 ---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP 160
>BC110351-1|AAI10352.1| 395|Homo sapiens KCNAB2 protein protein.
Length = 395
Score = 46.4 bits (105), Expect = 1e-04
Identities = 40/117 (34%), Positives = 57/117 (48%), Gaps = 11/117 (9%)
Frame = +1
Query: 181 VALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQVGRALTKK 348
+ LGTW+ Q+T++ EQ + A + G DTA Y E +G + KK
Sbjct: 52 LGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK 106
Query: 349 FSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYLIHWP 498
G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+ + P
Sbjct: 107 ---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP 160
>AL035406-6|CAI19886.1| 253|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 253
Score = 46.4 bits (105), Expect = 1e-04
Identities = 40/117 (34%), Positives = 57/117 (48%), Gaps = 11/117 (9%)
Frame = +1
Query: 181 VALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQVGRALTKK 348
+ LGTW+ Q+T++ EQ + A + G DTA Y E +G + KK
Sbjct: 52 LGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK 106
Query: 349 FSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYLIHWP 498
G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+ + P
Sbjct: 107 ---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP 160
>AL035406-5|CAI19887.1| 254|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 254
Score = 46.4 bits (105), Expect = 1e-04
Identities = 40/117 (34%), Positives = 57/117 (48%), Gaps = 11/117 (9%)
Frame = +1
Query: 181 VALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQVGRALTKK 348
+ LGTW+ Q+T++ EQ + A + G DTA Y E +G + KK
Sbjct: 38 LGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK 92
Query: 349 FSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYLIHWP 498
G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+ + P
Sbjct: 93 ---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP 146
>AL035406-4|CAC08512.1| 367|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 367
Score = 46.4 bits (105), Expect = 1e-04
Identities = 40/117 (34%), Positives = 57/117 (48%), Gaps = 11/117 (9%)
Frame = +1
Query: 181 VALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQVGRALTKK 348
+ LGTW+ Q+T++ EQ + A + G DTA Y E +G + KK
Sbjct: 52 LGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK 106
Query: 349 FSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYLIHWP 498
G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+ + P
Sbjct: 107 ---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP 160
>AL035406-3|CAI19885.1| 353|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 353
Score = 46.4 bits (105), Expect = 1e-04
Identities = 40/117 (34%), Positives = 57/117 (48%), Gaps = 11/117 (9%)
Frame = +1
Query: 181 VALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQVGRALTKK 348
+ LGTW+ Q+T++ EQ + A + G DTA Y E +G + KK
Sbjct: 38 LGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK 92
Query: 349 FSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYLIHWP 498
G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+ + P
Sbjct: 93 ---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP 146
>AK131252-1|BAD18431.1| 415|Homo sapiens protein ( Homo sapiens
cDNA FLJ16180 fis, clone BRHIP3000240, highly similar
to Homo sapiens potassium channel beta 2 subunit
(HKvbeta2.2) mRNA. ).
Length = 415
Score = 46.4 bits (105), Expect = 1e-04
Identities = 40/117 (34%), Positives = 57/117 (48%), Gaps = 11/117 (9%)
Frame = +1
Query: 181 VALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQVGRALTKK 348
+ LGTW+ Q+T++ EQ + A + G DTA Y E +G + KK
Sbjct: 85 LGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK 139
Query: 349 FSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYLIHWP 498
G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+ + P
Sbjct: 140 ---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP 193
>AF044253-1|AAB99859.1| 353|Homo sapiens potassium channel beta 2
subunit protein.
Length = 353
Score = 46.4 bits (105), Expect = 1e-04
Identities = 40/117 (34%), Positives = 57/117 (48%), Gaps = 11/117 (9%)
Frame = +1
Query: 181 VALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQVGRALTKK 348
+ LGTW+ Q+T++ EQ + A + G DTA Y E +G + KK
Sbjct: 38 LGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK 92
Query: 349 FSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYLIHWP 498
G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+ + P
Sbjct: 93 ---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP 146
>AF029749-1|AAB84170.1| 367|Homo sapiens potassium channel beta 2
subunit protein.
Length = 367
Score = 46.4 bits (105), Expect = 1e-04
Identities = 40/117 (34%), Positives = 57/117 (48%), Gaps = 11/117 (9%)
Frame = +1
Query: 181 VALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQVGRALTKK 348
+ LGTW+ Q+T++ EQ + A + G DTA Y E +G + KK
Sbjct: 52 LGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK 106
Query: 349 FSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYLIHWP 498
G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+ + P
Sbjct: 107 ---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRP 160
>AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthase
protein.
Length = 67
Score = 46.0 bits (104), Expect = 2e-04
Identities = 23/49 (46%), Positives = 31/49 (63%), Gaps = 2/49 (4%)
Frame = +1
Query: 523 LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KP 663
+ D VD TW M K GL KSIG+SNFN+ Q++ I++ GL+ KP
Sbjct: 15 IFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKP 63
>CR542264-1|CAG47060.1| 353|Homo sapiens KCNAB2 protein.
Length = 353
Score = 44.0 bits (99), Expect = 8e-04
Identities = 39/117 (33%), Positives = 56/117 (47%), Gaps = 11/117 (9%)
Frame = +1
Query: 181 VALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQVGRALTKK 348
+ LGTW+ Q+T++ EQ + A + G DTA Y E +G + KK
Sbjct: 38 LGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK 92
Query: 349 FSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYLIHWP 498
G +R S+ ITTK+ W E R+ +I L+ SLE LEYVD+ + P
Sbjct: 93 ---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERRQLEYVDVVFANRP 146
>BC099634-1|AAH99634.1| 404|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 3
protein.
Length = 404
Score = 42.7 bits (96), Expect = 0.002
Identities = 39/111 (35%), Positives = 53/111 (47%), Gaps = 11/111 (9%)
Frame = +1
Query: 181 VALGTWLGHRPKGKVVQVTNDTEQAVI-YALEAGYTHIDTAYKYGI---EDQVGRALTKK 348
+ LGTW+ Q++++T + V+ A E G DTA Y E +G L K
Sbjct: 93 LGLGTWVTFGS-----QISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTLGNILKSK 147
Query: 349 FSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDL 480
G +R S ITTK+ W E R+ +I LR SLE L L YVD+
Sbjct: 148 ---GWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDI 195
>BC096234-1|AAH96234.1| 404|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 3
protein.
Length = 404
Score = 42.7 bits (96), Expect = 0.002
Identities = 39/111 (35%), Positives = 53/111 (47%), Gaps = 11/111 (9%)
Frame = +1
Query: 181 VALGTWLGHRPKGKVVQVTNDTEQAVI-YALEAGYTHIDTAYKYGI---EDQVGRALTKK 348
+ LGTW+ Q++++T + V+ A E G DTA Y E +G L K
Sbjct: 93 LGLGTWVTFGS-----QISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTLGNILKSK 147
Query: 349 FSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDL 480
G +R S ITTK+ W E R+ +I LR SLE L L YVD+
Sbjct: 148 ---GWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDI 195
>BC096232-1|AAH96232.1| 404|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 3
protein.
Length = 404
Score = 42.7 bits (96), Expect = 0.002
Identities = 39/111 (35%), Positives = 53/111 (47%), Gaps = 11/111 (9%)
Frame = +1
Query: 181 VALGTWLGHRPKGKVVQVTNDTEQAVI-YALEAGYTHIDTAYKYGI---EDQVGRALTKK 348
+ LGTW+ Q++++T + V+ A E G DTA Y E +G L K
Sbjct: 93 LGLGTWVTFGS-----QISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTLGNILKSK 147
Query: 349 FSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDL 480
G +R S ITTK+ W E R+ +I LR SLE L L YVD+
Sbjct: 148 ---GWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDI 195
>AF016411-1|AAB92499.1| 404|Homo sapiens KCNA3.1B protein.
Length = 404
Score = 42.7 bits (96), Expect = 0.002
Identities = 39/111 (35%), Positives = 53/111 (47%), Gaps = 11/111 (9%)
Frame = +1
Query: 181 VALGTWLGHRPKGKVVQVTNDTEQAVI-YALEAGYTHIDTAYKYGI---EDQVGRALTKK 348
+ LGTW+ Q++++T + V+ A E G DTA Y E +G L K
Sbjct: 93 LGLGTWVTFGS-----QISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTLGNILKSK 147
Query: 349 FSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDL 480
G +R S ITTK+ W E R+ +I LR SLE L L YVD+
Sbjct: 148 ---GWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDI 195
>AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto
reductase protein.
Length = 45
Score = 37.9 bits (84), Expect = 0.049
Identities = 15/38 (39%), Positives = 23/38 (60%)
Frame = +1
Query: 394 LWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 507
+W ++ E V L SL+ L L Y+DLYL H+P+ +
Sbjct: 1 VWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVPL 38
>AF026947-1|AAC52104.1| 330|Homo sapiens aflatoxin aldehyde
reductase AFAR protein.
Length = 330
Score = 34.3 bits (75), Expect = 0.61
Identities = 45/178 (25%), Positives = 71/178 (39%), Gaps = 9/178 (5%)
Frame = +1
Query: 253 AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 423
AV LE G+T +DTA+ Y G + + L G R I W+ + +
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89
Query: 424 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 603
V L SL+ L VDL+ +H P ++ T ++ +T + G +G
Sbjct: 90 VRSQLETSLKRLQCPQVDLFYLHTP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140
Query: 604 ISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTP 759
+SN+ ++ I +G P+ Q N +Q ELF R + AY P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNP 198
>Y16675-1|CAA76347.1| 330|Homo sapiens aflatoxin B1-aldehyde
reductase protein.
Length = 330
Score = 33.9 bits (74), Expect = 0.80
Identities = 45/178 (25%), Positives = 71/178 (39%), Gaps = 9/178 (5%)
Frame = +1
Query: 253 AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 423
AV LE G+T +DTA+ Y G + + L G R I W+ + +
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89
Query: 424 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 603
V L SL+ L VDL+ +H P ++ T ++ +T + G +G
Sbjct: 90 VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140
Query: 604 ISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTP 759
+SN+ ++ I +G P+ Q N +Q ELF R + AY P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNP 198
>BT007347-1|AAP36011.1| 330|Homo sapiens aldo-keto reductase family
7, member A2 (aflatoxin aldehyde reductase) protein.
Length = 330
Score = 33.9 bits (74), Expect = 0.80
Identities = 45/178 (25%), Positives = 71/178 (39%), Gaps = 9/178 (5%)
Frame = +1
Query: 253 AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 423
AV LE G+T +DTA+ Y G + + L G R I W+ + +
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89
Query: 424 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 603
V L SL+ L VDL+ +H P ++ T ++ +T + G +G
Sbjct: 90 VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140
Query: 604 ISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTP 759
+SN+ ++ I +G P+ Q N +Q ELF R + AY P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNP 198
>BC013996-1|AAH13996.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 33.9 bits (74), Expect = 0.80
Identities = 45/178 (25%), Positives = 71/178 (39%), Gaps = 9/178 (5%)
Frame = +1
Query: 253 AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 423
AV LE G+T +DTA+ Y G + + L G R I W+ + +
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89
Query: 424 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 603
V L SL+ L VDL+ +H P ++ T ++ +T + G +G
Sbjct: 90 VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140
Query: 604 ISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTP 759
+SN+ ++ I +G P+ Q N +Q ELF R + AY P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNP 198
>BC012171-1|AAH12171.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 33.9 bits (74), Expect = 0.80
Identities = 45/178 (25%), Positives = 71/178 (39%), Gaps = 9/178 (5%)
Frame = +1
Query: 253 AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 423
AV LE G+T +DTA+ Y G + + L G R I W+ + +
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89
Query: 424 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 603
V L SL+ L VDL+ +H P ++ T ++ +T + G +G
Sbjct: 90 VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140
Query: 604 ISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTP 759
+SN+ ++ I +G P+ Q N +Q ELF R + AY P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNP 198
>BC011586-1|AAH11586.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 33.9 bits (74), Expect = 0.80
Identities = 45/178 (25%), Positives = 71/178 (39%), Gaps = 9/178 (5%)
Frame = +1
Query: 253 AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 423
AV LE G+T +DTA+ Y G + + L G R I W+ + +
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89
Query: 424 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 603
V L SL+ L VDL+ +H P ++ T ++ +T + G +G
Sbjct: 90 VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140
Query: 604 ISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTP 759
+SN+ ++ I +G P+ Q N +Q ELF R + AY P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNP 198
>BC010852-1|AAH10852.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 33.9 bits (74), Expect = 0.80
Identities = 45/178 (25%), Positives = 71/178 (39%), Gaps = 9/178 (5%)
Frame = +1
Query: 253 AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 423
AV LE G+T +DTA+ Y G + + L G R I W+ + +
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89
Query: 424 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 603
V L SL+ L VDL+ +H P ++ T ++ +T + G +G
Sbjct: 90 VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140
Query: 604 ISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTP 759
+SN+ ++ I +G P+ Q N +Q ELF R + AY P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNP 198
>BC007352-1|AAH07352.2| 358|Homo sapiens AKR7A2 protein protein.
Length = 358
Score = 33.9 bits (74), Expect = 0.80
Identities = 45/178 (25%), Positives = 71/178 (39%), Gaps = 9/178 (5%)
Frame = +1
Query: 253 AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 423
AV LE G+T +DTA+ Y G + + L G R I W+ + +
Sbjct: 58 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 117
Query: 424 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 603
V L SL+ L VDL+ +H P ++ T ++ +T + G +G
Sbjct: 118 VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 168
Query: 604 ISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTP 759
+SN+ ++ I +G P+ Q N +Q ELF R + AY P
Sbjct: 169 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNP 226
>BC004111-1|AAH04111.3| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 33.9 bits (74), Expect = 0.80
Identities = 45/178 (25%), Positives = 71/178 (39%), Gaps = 9/178 (5%)
Frame = +1
Query: 253 AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 423
AV LE G+T +DTA+ Y G + + L G R I W+ + +
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89
Query: 424 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 603
V L SL+ L VDL+ +H P ++ T ++ +T + G +G
Sbjct: 90 VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140
Query: 604 ISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTP 759
+SN+ ++ I +G P+ Q N +Q ELF R + AY P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNP 198
>AL035413-8|CAB72321.1| 330|Homo sapiens aldo-keto reductase family
7, member A2 (aflatoxin aldehyde reductase) protein.
Length = 330
Score = 33.9 bits (74), Expect = 0.80
Identities = 45/178 (25%), Positives = 71/178 (39%), Gaps = 9/178 (5%)
Frame = +1
Query: 253 AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 423
AV LE G+T +DTA+ Y G + + L G R I W+ + +
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89
Query: 424 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 603
V L SL+ L VDL+ +H P ++ T ++ +T + G +G
Sbjct: 90 VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140
Query: 604 ISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTP 759
+SN+ ++ I +G P+ Q N +Q ELF R + AY P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNP 198
>BX537954-1|CAD97921.1| 2210|Homo sapiens hypothetical protein
protein.
Length = 2210
Score = 31.9 bits (69), Expect = 3.2
Identities = 18/57 (31%), Positives = 31/57 (54%), Gaps = 1/57 (1%)
Frame = -1
Query: 815 RQSSAEERLVELARNSDPKGVYAITTMSFSRQNLKS-SGCCRLRFNSICKAEGFSSP 648
+Q+ ++R E+ + P GV + + S+ L+S S C L N + + +GFSSP
Sbjct: 1434 KQNDLQKRKGEIEEDLKPNGVLSRSAKERSKLKLQSNSNSCHL-VNGVVRIDGFSSP 1489
>M64590-1|AAA36463.1| 1020|Homo sapiens glycine decarboxylase
protein.
Length = 1020
Score = 31.1 bits (67), Expect = 5.7
Identities = 14/37 (37%), Positives = 24/37 (64%)
Frame = +1
Query: 364 KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 474
KR S F+T +++NSYH ++ ++K LEN ++ V
Sbjct: 514 KRTSPFLTHQVFNSYHSETNIVRYMKK-LENKDISLV 549
>M63635-1|AAA36478.1| 1020|Homo sapiens glycine decarboxylase
protein.
Length = 1020
Score = 31.1 bits (67), Expect = 5.7
Identities = 14/37 (37%), Positives = 24/37 (64%)
Frame = +1
Query: 364 KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 474
KR S F+T +++NSYH ++ ++K LEN ++ V
Sbjct: 514 KRTSPFLTHQVFNSYHSETNIVRYMKK-LENKDISLV 549
>D90239-1|BAA14286.1| 1020|Homo sapiens glycine decarboxylase
precursor protein.
Length = 1020
Score = 31.1 bits (67), Expect = 5.7
Identities = 14/37 (37%), Positives = 24/37 (64%)
Frame = +1
Query: 364 KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 474
KR S F+T +++NSYH ++ ++K LEN ++ V
Sbjct: 514 KRTSPFLTHQVFNSYHSETNIVRYMKK-LENKDISLV 549
>BC111995-1|AAI11996.1| 1020|Homo sapiens glycine dehydrogenase
(decarboxylating) protein.
Length = 1020
Score = 31.1 bits (67), Expect = 5.7
Identities = 14/37 (37%), Positives = 24/37 (64%)
Frame = +1
Query: 364 KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 474
KR S F+T +++NSYH ++ ++K LEN ++ V
Sbjct: 514 KRTSPFLTHQVFNSYHSETNIVRYMKK-LENKDISLV 549
>BC111993-1|AAI11994.1| 1020|Homo sapiens glycine dehydrogenase
(decarboxylating) protein.
Length = 1020
Score = 31.1 bits (67), Expect = 5.7
Identities = 14/37 (37%), Positives = 24/37 (64%)
Frame = +1
Query: 364 KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 474
KR S F+T +++NSYH ++ ++K LEN ++ V
Sbjct: 514 KRTSPFLTHQVFNSYHSETNIVRYMKK-LENKDISLV 549
>AL353718-2|CAH74116.1| 1036|Homo sapiens glycine dehydrogenase
(decarboxylating) protein.
Length = 1036
Score = 31.1 bits (67), Expect = 5.7
Identities = 14/37 (37%), Positives = 24/37 (64%)
Frame = +1
Query: 364 KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 474
KR S F+T +++NSYH ++ ++K LEN ++ V
Sbjct: 514 KRTSPFLTHQVFNSYHSETNIVRYMKK-LENKDISLV 549
>AL162411-3|CAH69992.1| 1036|Homo sapiens glycine dehydrogenase
(decarboxylating) protein.
Length = 1036
Score = 31.1 bits (67), Expect = 5.7
Identities = 14/37 (37%), Positives = 24/37 (64%)
Frame = +1
Query: 364 KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 474
KR S F+T +++NSYH ++ ++K LEN ++ V
Sbjct: 514 KRTSPFLTHQVFNSYHSETNIVRYMKK-LENKDISLV 549
>AF246134-1|AAK28443.2| 331|Homo sapiens glycine decarboxylase
P-protein protein.
Length = 331
Score = 31.1 bits (67), Expect = 5.7
Identities = 14/37 (37%), Positives = 24/37 (64%)
Frame = +1
Query: 364 KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 474
KR S F+T +++NSYH ++ ++K LEN ++ V
Sbjct: 276 KRTSPFLTHQVFNSYHSETNIVRYMKK-LENKDISLV 311
>BC071744-1|AAH71744.1| 157|Homo sapiens UTY protein protein.
Length = 157
Score = 30.7 bits (66), Expect = 7.5
Identities = 15/43 (34%), Positives = 20/43 (46%), Gaps = 2/43 (4%)
Frame = +1
Query: 16 LXHSRAPFHLWAIWSFHSQWPSG--PVSCFACARCVXLALPCS 138
L R P+ +I+ + WP G VSC C R + PCS
Sbjct: 87 LPRPRVPYRPASIYFGSAPWPRGRKSVSCLCCPRTLEYFAPCS 129
>AK092420-1|BAC03884.1| 357|Homo sapiens protein ( Homo sapiens
cDNA FLJ35101 fis, clone PLACE6006418, weakly similar to
PUTATIVE PRE-MRNA SPLICING FACTOR ATP-DEPENDENT RNA
HELICASE. ).
Length = 357
Score = 30.3 bits (65), Expect = 9.9
Identities = 15/40 (37%), Positives = 25/40 (62%)
Frame = +1
Query: 565 IDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 684
+DA+K+ +T + +F+ IQ +IDSGLE S + E+
Sbjct: 315 MDARKVVVTHWLADFSFSLPSIQHVIDSGLELRSVSEREI 354
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 130,661,675
Number of Sequences: 237096
Number of extensions: 2953410
Number of successful extensions: 12638
Number of sequences better than 10.0: 131
Number of HSP's better than 10.0 without gapping: 11837
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 12383
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11548247776
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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