Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP21_F_D24
(933 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
J04031-1|AAA59574.1| 935|Homo sapiens MTHFD protein. 317 3e-86
BC050420-1|AAH50420.1| 935|Homo sapiens methylenetetrahydrofola... 317 3e-86
BC009806-1|AAH09806.1| 935|Homo sapiens methylenetetrahydrofola... 317 3e-86
X16396-1|CAA34431.1| 344|Homo sapiens protein ( Human mRNA for ... 171 2e-42
BC017054-1|AAH17054.2| 350|Homo sapiens methylenetetrahydrofola... 171 2e-42
BC001548-1|AAH01548.1| 344|Homo sapiens methylene tetrahydrofol... 171 2e-42
AC073263-5|AAX93061.1| 344|Homo sapiens unknown protein. 171 2e-42
AK223041-1|BAD96761.1| 344|Homo sapiens methylene tetrahydrofol... 170 7e-42
AK222826-1|BAD96546.1| 344|Homo sapiens methylene tetrahydrofol... 170 7e-42
BC015062-1|AAH15062.1| 248|Homo sapiens methylenetetrahydrofola... 144 5e-34
AY374130-1|AAQ82696.1| 978|Homo sapiens C1-tetrahydrofolate syn... 118 3e-26
AL133260-2|CAI95678.1| 978|Homo sapiens methylenetetrahydrofola... 118 3e-26
AL117452-1|CAB55934.1| 917|Homo sapiens hypothetical protein pr... 118 3e-26
AL049694-3|CAI95774.1| 978|Homo sapiens methylenetetrahydrofola... 118 3e-26
AL035086-7|CAI42794.1| 978|Homo sapiens methylenetetrahydrofola... 118 3e-26
AB127387-1|BAD93193.1| 978|Homo sapiens mitochondrial C1-tetrah... 118 3e-26
BC110319-1|AAI10320.1| 900|Homo sapiens MTHFD1L protein protein. 118 4e-26
AL049694-4|CAI95775.1| 331|Homo sapiens methylenetetrahydrofola... 113 7e-25
AL035086-8|CAI42795.1| 331|Homo sapiens methylenetetrahydrofola... 113 7e-25
AK023167-1|BAB14441.1| 236|Homo sapiens ohydrolase (EC 1.5.1.15... 113 9e-25
AY374131-1|AAQ82697.1| 275|Homo sapiens truncated C1-tetrahydro... 96 2e-19
BC032771-1|AAH32771.1| 146|Homo sapiens MTHFD2L protein protein. 95 2e-19
AL035086-6|CAI42793.1| 114|Homo sapiens methylenetetrahydrofola... 75 5e-13
BC037529-1|AAH37529.2| 106|Homo sapiens MTHFD2L protein protein. 64 7e-10
AL035086-4|CAI42792.1| 120|Homo sapiens methylenetetrahydrofola... 54 1e-06
BC017477-1|AAH17477.2| 775|Homo sapiens MTHFD1L protein protein. 52 4e-06
AL035086-5|CAI42791.1| 120|Homo sapiens methylenetetrahydrofola... 49 2e-05
BC006399-1|AAH06399.2| 396|Homo sapiens reticulon 4 interacting... 34 0.85
AY063761-1|AAL40856.1| 396|Homo sapiens NOGO-interacting mitoch... 34 0.85
AL390074-5|CAH72095.1| 396|Homo sapiens reticulon 4 interacting... 34 0.85
BC065771-1|AAH65771.1| 70|Homo sapiens MTHFD2L protein protein. 33 2.0
AF336861-1|AAK64603.1| 396|Homo sapiens NOGO-interacting mitoch... 31 4.5
AK131318-1|BAD18481.1| 276|Homo sapiens protein ( Homo sapiens ... 31 6.0
AK095207-1|BAC04499.1| 296|Homo sapiens protein ( Homo sapiens ... 31 6.0
BC016821-1|AAH16821.1| 343|Homo sapiens MAP3K12 binding inhibit... 31 7.9
BC005197-1|AAH05197.1| 344|Homo sapiens MAP3K12 binding inhibit... 31 7.9
AB038523-1|BAA94083.1| 344|Homo sapiens MBIP protein. 31 7.9
>J04031-1|AAA59574.1| 935|Homo sapiens MTHFD protein.
Length = 935
Score = 317 bits (779), Expect = 3e-86
Identities = 148/253 (58%), Positives = 195/253 (77%), Gaps = 1/253 (0%)
Frame = +3
Query: 117 GIEVAGSIENDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYIRMKLKAAEKIGIAAE 296
G E++ I L+ QVT+L+ + GF PRLAI+QVG R+DSN+YI +KLKAAE+IGI A
Sbjct: 9 GKEISAQIRARLKNQVTQLKEQVPGFTPRLAILQVGNRDDSNLYINVKLKAAEEIGIKAT 68
Query: 297 HIRLPRDITEIELLAKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKDVDGLN 476
HI+LPR TE E++ ITSLNE +VHG +VQ+PLDS+++I+ V +A++P+KDVDGL
Sbjct: 69 HIKLPRTTTESEVMKYITSLNEDSTVHGFLVQLPLDSENSINTEEVINAIAPEKDVDGLT 128
Query: 477 TINEGRVAVGDLSG-FIPCTPAGCVELIKKTGVTIAGKNVVVLGRSRIVGTPVSELLKWE 653
+IN GR+A GDL+ FIPCTP GC+ELIK+TGV IAG++ VV+GRS+IVG P+ +LL W
Sbjct: 129 SINAGRLARGDLNDCFIPCTPKGCLELIKETGVPIAGRHAVVVGRSKIVGAPMHDLLLWN 188
Query: 654 HATVTVCHSKTKNLSEITKTAEILVVAIGRPEXVRGSWIKPGAVVIDCGINAIEDPTKKS 833
+ATVT CHSKT +L E +ILVVA G+PE V+G WIKPGA+VIDCGIN + D K +
Sbjct: 189 NATVTTCHSKTAHLDEEVNKGDILVVATGQPEMVKGEWIKPGAIVIDCGINYVPDDKKPN 248
Query: 834 GQRLXGDVAYQXA 872
G+++ GDVAY A
Sbjct: 249 GRKVVGDVAYDEA 261
>BC050420-1|AAH50420.1| 935|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1, methenyltetrahydro
protein.
Length = 935
Score = 317 bits (779), Expect = 3e-86
Identities = 148/253 (58%), Positives = 195/253 (77%), Gaps = 1/253 (0%)
Frame = +3
Query: 117 GIEVAGSIENDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYIRMKLKAAEKIGIAAE 296
G E++ I L+ QVT+L+ + GF PRLAI+QVG R+DSN+YI +KLKAAE+IGI A
Sbjct: 9 GKEISAQIRARLKNQVTQLKEQVPGFTPRLAILQVGNRDDSNLYINVKLKAAEEIGIKAT 68
Query: 297 HIRLPRDITEIELLAKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKDVDGLN 476
HI+LPR TE E++ ITSLNE +VHG +VQ+PLDS+++I+ V +A++P+KDVDGL
Sbjct: 69 HIKLPRTTTESEVMKYITSLNEDSTVHGFLVQLPLDSENSINTEEVINAIAPEKDVDGLT 128
Query: 477 TINEGRVAVGDLSG-FIPCTPAGCVELIKKTGVTIAGKNVVVLGRSRIVGTPVSELLKWE 653
+IN GR+A GDL+ FIPCTP GC+ELIK+TGV IAG++ VV+GRS+IVG P+ +LL W
Sbjct: 129 SINAGRLARGDLNDCFIPCTPKGCLELIKETGVPIAGRHAVVVGRSKIVGAPMHDLLLWN 188
Query: 654 HATVTVCHSKTKNLSEITKTAEILVVAIGRPEXVRGSWIKPGAVVIDCGINAIEDPTKKS 833
+ATVT CHSKT +L E +ILVVA G+PE V+G WIKPGA+VIDCGIN + D K +
Sbjct: 189 NATVTTCHSKTAHLDEEVNKGDILVVATGQPEMVKGEWIKPGAIVIDCGINYVPDDKKPN 248
Query: 834 GQRLXGDVAYQXA 872
G+++ GDVAY A
Sbjct: 249 GRKVVGDVAYDEA 261
>BC009806-1|AAH09806.1| 935|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1, methenyltetrahydro
protein.
Length = 935
Score = 317 bits (779), Expect = 3e-86
Identities = 148/253 (58%), Positives = 195/253 (77%), Gaps = 1/253 (0%)
Frame = +3
Query: 117 GIEVAGSIENDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYIRMKLKAAEKIGIAAE 296
G E++ I L+ QVT+L+ + GF PRLAI+QVG R+DSN+YI +KLKAAE+IGI A
Sbjct: 9 GKEISAQIRARLKNQVTQLKEQVPGFTPRLAILQVGNRDDSNLYINVKLKAAEEIGIKAT 68
Query: 297 HIRLPRDITEIELLAKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKDVDGLN 476
HI+LPR TE E++ ITSLNE +VHG +VQ+PLDS+++I+ V +A++P+KDVDGL
Sbjct: 69 HIKLPRTTTESEVMKYITSLNEDSTVHGFLVQLPLDSENSINTEEVINAIAPEKDVDGLT 128
Query: 477 TINEGRVAVGDLSG-FIPCTPAGCVELIKKTGVTIAGKNVVVLGRSRIVGTPVSELLKWE 653
+IN GR+A GDL+ FIPCTP GC+ELIK+TGV IAG++ VV+GRS+IVG P+ +LL W
Sbjct: 129 SINAGRLARGDLNDCFIPCTPKGCLELIKETGVPIAGRHAVVVGRSKIVGAPMHDLLLWN 188
Query: 654 HATVTVCHSKTKNLSEITKTAEILVVAIGRPEXVRGSWIKPGAVVIDCGINAIEDPTKKS 833
+ATVT CHSKT +L E +ILVVA G+PE V+G WIKPGA+VIDCGIN + D K +
Sbjct: 189 NATVTTCHSKTAHLDEEVNKGDILVVATGQPEMVKGEWIKPGAIVIDCGINYVPDDKKPN 248
Query: 834 GQRLXGDVAYQXA 872
G+++ GDVAY A
Sbjct: 249 GRKVVGDVAYDEA 261
>X16396-1|CAA34431.1| 344|Homo sapiens protein ( Human mRNA for
NAD-dependent methylene tetrahydrofolate dehydrogenase
cyclohydrolase (EC 1.5.1.15). ).
Length = 344
Score = 171 bits (417), Expect = 2e-42
Identities = 105/260 (40%), Positives = 152/260 (58%), Gaps = 10/260 (3%)
Frame = +3
Query: 117 GIEVAGSIENDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYIRMKLKAAEKIGIAAE 296
G ++A I+ ++RQ+V + + P L+++ VG S+ Y+ K +AA +GI +E
Sbjct: 36 GRKLAQQIKQEVRQEVEEWVASGNK-RPHLSVILVGENPASHSYVLNKTRAAAVVGINSE 94
Query: 297 HIRLPRDITEIELLAKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKDVDGLN 476
I P I+E ELL I LN +V G++VQ+PL +H ID R+ +AVSPDKDVDG +
Sbjct: 95 TIMKPASISEEELLNLINKLNNDDNVDGLLVQLPL-PEH-IDERRICNAVSPDKDVDGFH 152
Query: 477 TINEGRVAVGDLSGFIPCTPAGCVELIKKTGVTIAGKNVVVLGRSRIVGTPVSELLKWE- 653
IN GR+ + D +P TP G E+IK+TG+ GKNVVV GRS+ VG P++ LL +
Sbjct: 153 VINVGRMCL-DQYSMLPATPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDG 211
Query: 654 -------HATVTVCHSKT--KNLSEITKTAEILVVAIGRPEXVRGSWIKPGAVVIDCGIN 806
ATVT+ H T + L + T A+I++ A G P + IK GA VID GIN
Sbjct: 212 AHERPGGDATVTISHRYTPKEQLKKHTILADIVISAAGIPNLITADMIKEGAAVIDVGIN 271
Query: 807 AIEDPTKKSGQRLXGDVAYQ 866
+ DP + +L GDV ++
Sbjct: 272 RVHDPV-TAKPKLVGDVDFE 290
>BC017054-1|AAH17054.2| 350|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 2, methenyltetrahydro
protein.
Length = 350
Score = 171 bits (417), Expect = 2e-42
Identities = 105/260 (40%), Positives = 152/260 (58%), Gaps = 10/260 (3%)
Frame = +3
Query: 117 GIEVAGSIENDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYIRMKLKAAEKIGIAAE 296
G ++A I+ ++RQ+V + + P L+++ VG S+ Y+ K +AA +GI +E
Sbjct: 42 GRKLAQQIKQEVRQEVEEWVASGNK-RPHLSVILVGENPASHSYVLNKTRAAAVVGINSE 100
Query: 297 HIRLPRDITEIELLAKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKDVDGLN 476
I P I+E ELL I LN +V G++VQ+PL +H ID R+ +AVSPDKDVDG +
Sbjct: 101 TIMKPASISEEELLNLINKLNNDDNVDGLLVQLPL-PEH-IDERRICNAVSPDKDVDGFH 158
Query: 477 TINEGRVAVGDLSGFIPCTPAGCVELIKKTGVTIAGKNVVVLGRSRIVGTPVSELLKWE- 653
IN GR+ + D +P TP G E+IK+TG+ GKNVVV GRS+ VG P++ LL +
Sbjct: 159 VINVGRMCL-DQYSMLPATPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDG 217
Query: 654 -------HATVTVCHSKT--KNLSEITKTAEILVVAIGRPEXVRGSWIKPGAVVIDCGIN 806
ATVT+ H T + L + T A+I++ A G P + IK GA VID GIN
Sbjct: 218 AHERPGGDATVTISHRYTPKEQLKKHTILADIVISAAGIPNLITADMIKEGAAVIDVGIN 277
Query: 807 AIEDPTKKSGQRLXGDVAYQ 866
+ DP + +L GDV ++
Sbjct: 278 RVHDPV-TAKPKLVGDVDFE 296
>BC001548-1|AAH01548.1| 344|Homo sapiens methylene tetrahydrofolate
dehydrogenase 2, precursor protein.
Length = 344
Score = 171 bits (417), Expect = 2e-42
Identities = 105/260 (40%), Positives = 152/260 (58%), Gaps = 10/260 (3%)
Frame = +3
Query: 117 GIEVAGSIENDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYIRMKLKAAEKIGIAAE 296
G ++A I+ ++RQ+V + + P L+++ VG S+ Y+ K +AA +GI +E
Sbjct: 36 GRKLAQQIKQEVRQEVEEWVASGNK-RPHLSVILVGENPASHSYVLNKTRAAAVVGINSE 94
Query: 297 HIRLPRDITEIELLAKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKDVDGLN 476
I P I+E ELL I LN +V G++VQ+PL +H ID R+ +AVSPDKDVDG +
Sbjct: 95 TIMKPASISEEELLNLINKLNNDDNVDGLLVQLPL-PEH-IDERRICNAVSPDKDVDGFH 152
Query: 477 TINEGRVAVGDLSGFIPCTPAGCVELIKKTGVTIAGKNVVVLGRSRIVGTPVSELLKWE- 653
IN GR+ + D +P TP G E+IK+TG+ GKNVVV GRS+ VG P++ LL +
Sbjct: 153 VINVGRMCL-DQYSMLPATPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDG 211
Query: 654 -------HATVTVCHSKT--KNLSEITKTAEILVVAIGRPEXVRGSWIKPGAVVIDCGIN 806
ATVT+ H T + L + T A+I++ A G P + IK GA VID GIN
Sbjct: 212 AHERPGGDATVTISHRYTPKEQLKKHTILADIVISAAGIPNLITADMIKEGAAVIDVGIN 271
Query: 807 AIEDPTKKSGQRLXGDVAYQ 866
+ DP + +L GDV ++
Sbjct: 272 RVHDPV-TAKPKLVGDVDFE 290
>AC073263-5|AAX93061.1| 344|Homo sapiens unknown protein.
Length = 344
Score = 171 bits (417), Expect = 2e-42
Identities = 105/260 (40%), Positives = 152/260 (58%), Gaps = 10/260 (3%)
Frame = +3
Query: 117 GIEVAGSIENDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYIRMKLKAAEKIGIAAE 296
G ++A I+ ++RQ+V + + P L+++ VG S+ Y+ K +AA +GI +E
Sbjct: 36 GRKLAQQIKQEVRQEVEEWVASGNK-RPHLSVILVGENPASHSYVLNKTRAAAVVGINSE 94
Query: 297 HIRLPRDITEIELLAKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKDVDGLN 476
I P I+E ELL I LN +V G++VQ+PL +H ID R+ +AVSPDKDVDG +
Sbjct: 95 TIMKPASISEEELLNLINKLNNDDNVDGLLVQLPL-PEH-IDERRICNAVSPDKDVDGFH 152
Query: 477 TINEGRVAVGDLSGFIPCTPAGCVELIKKTGVTIAGKNVVVLGRSRIVGTPVSELLKWE- 653
IN GR+ + D +P TP G E+IK+TG+ GKNVVV GRS+ VG P++ LL +
Sbjct: 153 VINVGRMCL-DQYSMLPATPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDG 211
Query: 654 -------HATVTVCHSKT--KNLSEITKTAEILVVAIGRPEXVRGSWIKPGAVVIDCGIN 806
ATVT+ H T + L + T A+I++ A G P + IK GA VID GIN
Sbjct: 212 AHERPGGDATVTISHRYTPKEQLKKHTILADIVISAAGIPNLITADMIKEGAAVIDVGIN 271
Query: 807 AIEDPTKKSGQRLXGDVAYQ 866
+ DP + +L GDV ++
Sbjct: 272 RVHDPV-TAKPKLVGDVDFE 290
>AK223041-1|BAD96761.1| 344|Homo sapiens methylene tetrahydrofolate
dehydrogenase 2 precursor variant protein.
Length = 344
Score = 170 bits (413), Expect = 7e-42
Identities = 105/260 (40%), Positives = 151/260 (58%), Gaps = 10/260 (3%)
Frame = +3
Query: 117 GIEVAGSIENDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYIRMKLKAAEKIGIAAE 296
G ++A I+ ++RQ+V + + P L+++ VG S+ Y+ K +AA GI +E
Sbjct: 36 GRKLAQQIKQEVRQEVEEWVASGNK-RPHLSVILVGENPASHSYVLNKTRAAAVAGINSE 94
Query: 297 HIRLPRDITEIELLAKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKDVDGLN 476
I P I+E ELL I LN +V G++VQ+PL +H ID R+ +AVSPDKDVDG +
Sbjct: 95 TIMKPASISEEELLNLINKLNNDDNVDGLLVQLPL-PEH-IDERRICNAVSPDKDVDGFH 152
Query: 477 TINEGRVAVGDLSGFIPCTPAGCVELIKKTGVTIAGKNVVVLGRSRIVGTPVSELLKWE- 653
IN GR+ + D +P TP G E+IK+TG+ GKNVVV GRS+ VG P++ LL +
Sbjct: 153 VINVGRMCL-DQYSMLPATPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDG 211
Query: 654 -------HATVTVCHSKT--KNLSEITKTAEILVVAIGRPEXVRGSWIKPGAVVIDCGIN 806
ATVT+ H T + L + T A+I++ A G P + IK GA VID GIN
Sbjct: 212 AHERPGGDATVTISHRYTPKEQLKKHTILADIVISAAGIPNLITADMIKEGAAVIDVGIN 271
Query: 807 AIEDPTKKSGQRLXGDVAYQ 866
+ DP + +L GDV ++
Sbjct: 272 RVHDPV-TAKPKLVGDVDFE 290
>AK222826-1|BAD96546.1| 344|Homo sapiens methylene tetrahydrofolate
dehydrogenase 2 precursor variant protein.
Length = 344
Score = 170 bits (413), Expect = 7e-42
Identities = 104/260 (40%), Positives = 151/260 (58%), Gaps = 10/260 (3%)
Frame = +3
Query: 117 GIEVAGSIENDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYIRMKLKAAEKIGIAAE 296
G ++A I+ ++RQ+V + + P L+++ G S+ Y+ K +AA +GI +E
Sbjct: 36 GRKLAQQIKQEVRQEVEEWVASGNK-RPHLSVILAGENPASHSYVLNKTRAAAVVGINSE 94
Query: 297 HIRLPRDITEIELLAKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKDVDGLN 476
I P I+E ELL I LN +V G++VQ+PL +H ID R+ +AVSPDKDVDG +
Sbjct: 95 TIMKPASISEEELLNLINKLNNDDNVDGLLVQLPL-PEH-IDERRICNAVSPDKDVDGFH 152
Query: 477 TINEGRVAVGDLSGFIPCTPAGCVELIKKTGVTIAGKNVVVLGRSRIVGTPVSELLKWE- 653
IN GR+ + D +P TP G E+IK+TG+ GKNVVV GRS+ VG P++ LL +
Sbjct: 153 VINVGRMCL-DQYSMLPATPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDG 211
Query: 654 -------HATVTVCHSKT--KNLSEITKTAEILVVAIGRPEXVRGSWIKPGAVVIDCGIN 806
ATVT+ H T + L + T A+I++ A G P + IK GA VID GIN
Sbjct: 212 AHERPGGDATVTISHRYTPKEQLKKHTILADIVISAAGIPNLITADMIKEGAAVIDVGIN 271
Query: 807 AIEDPTKKSGQRLXGDVAYQ 866
+ DP + +L GDV ++
Sbjct: 272 RVHDPV-TAKPKLVGDVDFE 290
>BC015062-1|AAH15062.1| 248|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 2, methenyltetrahydro
protein.
Length = 248
Score = 144 bits (348), Expect = 5e-34
Identities = 86/196 (43%), Positives = 117/196 (59%), Gaps = 10/196 (5%)
Frame = +3
Query: 309 PRDITEIELLAKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKDVDGLNTINE 488
P I+E ELL I LN +V G++VQ+PL +H ID R+ +AVSPDKDVDG + IN
Sbjct: 3 PASISEEELLNLINKLNNDDNVDGLLVQLPLP-EH-IDERRICNAVSPDKDVDGFHVINV 60
Query: 489 GRVAVGDLSGFIPCTPAGCVELIKKTGVTIAGKNVVVLGRSRIVGTPVSELLKWE----- 653
GR+ + S +P TP G E+IK+TG+ GKNVVV GRS+ VG P++ LL +
Sbjct: 61 GRMCLDQYS-MLPATPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDGAHER 119
Query: 654 ---HATVTVCHSKT--KNLSEITKTAEILVVAIGRPEXVRGSWIKPGAVVIDCGINAIED 818
ATVT+ H T + L + T A+I++ A G P + IK GA VID GIN + D
Sbjct: 120 PGGDATVTISHRYTPKEQLKKHTILADIVISAAGIPNLITADMIKEGAAVIDVGINRVHD 179
Query: 819 PTKKSGQRLXGDVAYQ 866
P + +L GDV ++
Sbjct: 180 PV-TAKPKLVGDVDFE 194
>AY374130-1|AAQ82696.1| 978|Homo sapiens C1-tetrahydrofolate
synthase protein.
Length = 978
Score = 118 bits (284), Expect = 3e-26
Identities = 68/221 (30%), Positives = 122/221 (55%), Gaps = 1/221 (0%)
Frame = +3
Query: 138 IENDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYIRMKLKAAEKIGIAAEHIRLPRD 317
I+N ++ ++ L+ K F+P LAI+Q G D N+ + AE+ G+ HI LP D
Sbjct: 79 IQNS-KEVLSLLQEKNPAFKPVLAIIQAG---DDNLMQEINQNLAEEAGLNITHICLPPD 134
Query: 318 ITEIELLAKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKDVDGLNTINEGRV 497
+E E++ +I +NE VHG+ +Q+ + +++V +A+ P+KDVDG+ IN G++
Sbjct: 135 SSEAEIIDEILKINEDTRVHGLALQI----SENLFSNKVLNALKPEKDVDGVTDINLGKL 190
Query: 498 AVGDL-SGFIPCTPAGCVELIKKTGVTIAGKNVVVLGRSRIVGTPVSELLKWEHATVTVC 674
GD F+ +EL++K+GV + GK ++V+G + + L + + +
Sbjct: 191 VRGDAHECFVSPVAKAVIELLEKSGVNLDGKKILVVGAHGSLEAALQCLFQRKGSMTMSI 250
Query: 675 HSKTKNLSEITKTAEILVVAIGRPEXVRGSWIKPGAVVIDC 797
KT+ L A+I+V+ +PE + +WI+PG V++C
Sbjct: 251 QWKTRQLQSKLHEADIVVLGSPKPEEIPLTWIQPGTTVLNC 291
>AL133260-2|CAI95678.1| 978|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1-like protein.
Length = 978
Score = 118 bits (284), Expect = 3e-26
Identities = 68/221 (30%), Positives = 122/221 (55%), Gaps = 1/221 (0%)
Frame = +3
Query: 138 IENDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYIRMKLKAAEKIGIAAEHIRLPRD 317
I+N ++ ++ L+ K F+P LAI+Q G D N+ + AE+ G+ HI LP D
Sbjct: 79 IQNS-KEVLSLLQEKNPAFKPVLAIIQAG---DDNLMQEINQNLAEEAGLNITHICLPPD 134
Query: 318 ITEIELLAKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKDVDGLNTINEGRV 497
+E E++ +I +NE VHG+ +Q+ + +++V +A+ P+KDVDG+ IN G++
Sbjct: 135 SSEAEIIDEILKINEDTRVHGLALQI----SENLFSNKVLNALKPEKDVDGVTDINLGKL 190
Query: 498 AVGDL-SGFIPCTPAGCVELIKKTGVTIAGKNVVVLGRSRIVGTPVSELLKWEHATVTVC 674
GD F+ +EL++K+GV + GK ++V+G + + L + + +
Sbjct: 191 VRGDAHECFVSPVAKAVIELLEKSGVNLDGKKILVVGAHGSLEAALQCLFQRKGSMTMSI 250
Query: 675 HSKTKNLSEITKTAEILVVAIGRPEXVRGSWIKPGAVVIDC 797
KT+ L A+I+V+ +PE + +WI+PG V++C
Sbjct: 251 QWKTRQLQSKLHEADIVVLGSPKPEEIPLTWIQPGTTVLNC 291
>AL117452-1|CAB55934.1| 917|Homo sapiens hypothetical protein
protein.
Length = 917
Score = 118 bits (284), Expect = 3e-26
Identities = 68/221 (30%), Positives = 122/221 (55%), Gaps = 1/221 (0%)
Frame = +3
Query: 138 IENDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYIRMKLKAAEKIGIAAEHIRLPRD 317
I+N ++ ++ L+ K F+P LAI+Q G D N+ + AE+ G+ HI LP D
Sbjct: 18 IQNS-KEVLSLLQEKNPAFKPVLAIIQAG---DDNLMQEINQNLAEEAGLNITHICLPPD 73
Query: 318 ITEIELLAKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKDVDGLNTINEGRV 497
+E E++ +I +NE VHG+ +Q+ + +++V +A+ P+KDVDG+ IN G++
Sbjct: 74 SSEAEIIDEILKINEDTRVHGLALQI----SENLFSNKVLNALKPEKDVDGVTDINLGKL 129
Query: 498 AVGDL-SGFIPCTPAGCVELIKKTGVTIAGKNVVVLGRSRIVGTPVSELLKWEHATVTVC 674
GD F+ +EL++K+GV + GK ++V+G + + L + + +
Sbjct: 130 VRGDAHECFVSPVAKAVIELLEKSGVNLDGKKILVVGAHGSLEAALQCLFQRKGSMTMSI 189
Query: 675 HSKTKNLSEITKTAEILVVAIGRPEXVRGSWIKPGAVVIDC 797
KT+ L A+I+V+ +PE + +WI+PG V++C
Sbjct: 190 QWKTRQLQSKLHEADIVVLGSPKPEEIPLTWIQPGTTVLNC 230
>AL049694-3|CAI95774.1| 978|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1-like protein.
Length = 978
Score = 118 bits (284), Expect = 3e-26
Identities = 68/221 (30%), Positives = 122/221 (55%), Gaps = 1/221 (0%)
Frame = +3
Query: 138 IENDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYIRMKLKAAEKIGIAAEHIRLPRD 317
I+N ++ ++ L+ K F+P LAI+Q G D N+ + AE+ G+ HI LP D
Sbjct: 79 IQNS-KEVLSLLQEKNPAFKPVLAIIQAG---DDNLMQEINQNLAEEAGLNITHICLPPD 134
Query: 318 ITEIELLAKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKDVDGLNTINEGRV 497
+E E++ +I +NE VHG+ +Q+ + +++V +A+ P+KDVDG+ IN G++
Sbjct: 135 SSEAEIIDEILKINEDTRVHGLALQI----SENLFSNKVLNALKPEKDVDGVTDINLGKL 190
Query: 498 AVGDL-SGFIPCTPAGCVELIKKTGVTIAGKNVVVLGRSRIVGTPVSELLKWEHATVTVC 674
GD F+ +EL++K+GV + GK ++V+G + + L + + +
Sbjct: 191 VRGDAHECFVSPVAKAVIELLEKSGVNLDGKKILVVGAHGSLEAALQCLFQRKGSMTMSI 250
Query: 675 HSKTKNLSEITKTAEILVVAIGRPEXVRGSWIKPGAVVIDC 797
KT+ L A+I+V+ +PE + +WI+PG V++C
Sbjct: 251 QWKTRQLQSKLHEADIVVLGSPKPEEIPLTWIQPGTTVLNC 291
>AL035086-7|CAI42794.1| 978|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1-like protein.
Length = 978
Score = 118 bits (284), Expect = 3e-26
Identities = 68/221 (30%), Positives = 122/221 (55%), Gaps = 1/221 (0%)
Frame = +3
Query: 138 IENDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYIRMKLKAAEKIGIAAEHIRLPRD 317
I+N ++ ++ L+ K F+P LAI+Q G D N+ + AE+ G+ HI LP D
Sbjct: 79 IQNS-KEVLSLLQEKNPAFKPVLAIIQAG---DDNLMQEINQNLAEEAGLNITHICLPPD 134
Query: 318 ITEIELLAKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKDVDGLNTINEGRV 497
+E E++ +I +NE VHG+ +Q+ + +++V +A+ P+KDVDG+ IN G++
Sbjct: 135 SSEAEIIDEILKINEDTRVHGLALQI----SENLFSNKVLNALKPEKDVDGVTDINLGKL 190
Query: 498 AVGDL-SGFIPCTPAGCVELIKKTGVTIAGKNVVVLGRSRIVGTPVSELLKWEHATVTVC 674
GD F+ +EL++K+GV + GK ++V+G + + L + + +
Sbjct: 191 VRGDAHECFVSPVAKAVIELLEKSGVNLDGKKILVVGAHGSLEAALQCLFQRKGSMTMSI 250
Query: 675 HSKTKNLSEITKTAEILVVAIGRPEXVRGSWIKPGAVVIDC 797
KT+ L A+I+V+ +PE + +WI+PG V++C
Sbjct: 251 QWKTRQLQSKLHEADIVVLGSPKPEEIPLTWIQPGTTVLNC 291
>AB127387-1|BAD93193.1| 978|Homo sapiens mitochondrial
C1-tetrahydrofolate synthetase protein.
Length = 978
Score = 118 bits (284), Expect = 3e-26
Identities = 68/221 (30%), Positives = 122/221 (55%), Gaps = 1/221 (0%)
Frame = +3
Query: 138 IENDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYIRMKLKAAEKIGIAAEHIRLPRD 317
I+N ++ ++ L+ K F+P LAI+Q G D N+ + AE+ G+ HI LP D
Sbjct: 79 IQNS-KEVLSLLQEKNPAFKPVLAIIQAG---DDNLMQEINQNLAEEAGLNITHICLPPD 134
Query: 318 ITEIELLAKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKDVDGLNTINEGRV 497
+E E++ +I +NE VHG+ +Q+ + +++V +A+ P+KDVDG+ IN G++
Sbjct: 135 SSEAEIIDEILKINEDTRVHGLALQI----SENLFSNKVLNALKPEKDVDGVTDINLGKL 190
Query: 498 AVGDL-SGFIPCTPAGCVELIKKTGVTIAGKNVVVLGRSRIVGTPVSELLKWEHATVTVC 674
GD F+ +EL++K+GV + GK ++V+G + + L + + +
Sbjct: 191 VRGDAHECFVSPVAKAVIELLEKSGVNLDGKKILVVGAHGSLEAALQCLFQRKGSMTMSI 250
Query: 675 HSKTKNLSEITKTAEILVVAIGRPEXVRGSWIKPGAVVIDC 797
KT+ L A+I+V+ +PE + +WI+PG V++C
Sbjct: 251 QWKTRQLQSKLHEADIVVLGSPKPEEIPLTWIQPGTTVLNC 291
>BC110319-1|AAI10320.1| 900|Homo sapiens MTHFD1L protein protein.
Length = 900
Score = 118 bits (283), Expect = 4e-26
Identities = 66/216 (30%), Positives = 119/216 (55%), Gaps = 1/216 (0%)
Frame = +3
Query: 153 RQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYIRMKLKAAEKIGIAAEHIRLPRDITEIE 332
++ ++ L+ K F+P LAI+Q G D N+ + AE+ G+ HI LP D +E E
Sbjct: 5 KEVLSLLQEKNPAFKPVLAIIQAG---DDNLMQEINQNLAEEAGLNITHICLPPDSSEAE 61
Query: 333 LLAKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKDVDGLNTINEGRVAVGDL 512
++ +I +NE VHG+ +Q+ + +++V +A+ P+KDVDG+ IN G++ GD
Sbjct: 62 IIDEILKINEDTRVHGLALQI----SENLFSNKVLNALKPEKDVDGVTDINLGKLVRGDA 117
Query: 513 -SGFIPCTPAGCVELIKKTGVTIAGKNVVVLGRSRIVGTPVSELLKWEHATVTVCHSKTK 689
F+ +EL++K+GV + GK ++V+G + + L + + + KT+
Sbjct: 118 HECFVSPVAKAVIELLEKSGVNLDGKKILVVGAHGSLEAALQCLFQRKGSMTMSIQWKTR 177
Query: 690 NLSEITKTAEILVVAIGRPEXVRGSWIKPGAVVIDC 797
L A+I+V+ +PE + +WI+PG V++C
Sbjct: 178 QLQSKLHEADIVVLGSPKPEEIPLTWIQPGTTVLNC 213
>AL049694-4|CAI95775.1| 331|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1-like protein.
Length = 331
Score = 113 bits (273), Expect = 7e-25
Identities = 68/222 (30%), Positives = 122/222 (54%), Gaps = 2/222 (0%)
Frame = +3
Query: 138 IENDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYIRMKLKAAEKIGIAAEHIRLPRD 317
I+N ++ ++ L+ K F+P LAI+Q G D N+ + AE+ G+ HI LP D
Sbjct: 38 IQNS-KEVLSLLQEKNPAFKPVLAIIQAG---DDNLMQEINQNLAEEAGLNITHICLPPD 93
Query: 318 ITEIELLAKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKDVDGLNTINEGRV 497
+E E++ +I +NE VHG+ +Q+ + +++V +A+ P+KDVDG+ IN G++
Sbjct: 94 SSEAEIIDEILKINEDTRVHGLALQI----SENLFSNKVLNALKPEKDVDGVTDINLGKL 149
Query: 498 AVGDL-SGFIPCTPAGCVELIKKT-GVTIAGKNVVVLGRSRIVGTPVSELLKWEHATVTV 671
GD F+ +EL++K+ GV + GK ++V+G + + L + + +
Sbjct: 150 VRGDAHECFVSPVAKAVIELLEKSVGVNLDGKKILVVGAHGSLEAALQCLFQRKGSMTMS 209
Query: 672 CHSKTKNLSEITKTAEILVVAIGRPEXVRGSWIKPGAVVIDC 797
KT+ L A+I+V+ +PE + +WI+PG V++C
Sbjct: 210 IQWKTRQLQSKLHEADIVVLGSPKPEEIPLTWIQPGTTVLNC 251
>AL035086-8|CAI42795.1| 331|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1-like protein.
Length = 331
Score = 113 bits (273), Expect = 7e-25
Identities = 68/222 (30%), Positives = 122/222 (54%), Gaps = 2/222 (0%)
Frame = +3
Query: 138 IENDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYIRMKLKAAEKIGIAAEHIRLPRD 317
I+N ++ ++ L+ K F+P LAI+Q G D N+ + AE+ G+ HI LP D
Sbjct: 38 IQNS-KEVLSLLQEKNPAFKPVLAIIQAG---DDNLMQEINQNLAEEAGLNITHICLPPD 93
Query: 318 ITEIELLAKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKDVDGLNTINEGRV 497
+E E++ +I +NE VHG+ +Q+ + +++V +A+ P+KDVDG+ IN G++
Sbjct: 94 SSEAEIIDEILKINEDTRVHGLALQI----SENLFSNKVLNALKPEKDVDGVTDINLGKL 149
Query: 498 AVGDL-SGFIPCTPAGCVELIKKT-GVTIAGKNVVVLGRSRIVGTPVSELLKWEHATVTV 671
GD F+ +EL++K+ GV + GK ++V+G + + L + + +
Sbjct: 150 VRGDAHECFVSPVAKAVIELLEKSVGVNLDGKKILVVGAHGSLEAALQCLFQRKGSMTMS 209
Query: 672 CHSKTKNLSEITKTAEILVVAIGRPEXVRGSWIKPGAVVIDC 797
KT+ L A+I+V+ +PE + +WI+PG V++C
Sbjct: 210 IQWKTRQLQSKLHEADIVVLGSPKPEEIPLTWIQPGTTVLNC 251
>AK023167-1|BAB14441.1| 236|Homo sapiens ohydrolase (EC 1.5.1.15).
protein.
Length = 236
Score = 113 bits (272), Expect = 9e-25
Identities = 68/164 (41%), Positives = 97/164 (59%), Gaps = 10/164 (6%)
Frame = +3
Query: 417 IDAHRVTDAVSPDKDVDGLNTINEGRVAVGDLSGFIPCTPAGCVELIKKTGVTIAGKNVV 596
+D + + ++P+KDVDG + IN GR+ + D IP T + E+IK+TG+ GKNVV
Sbjct: 42 VDERTICNGIAPEKDVDGFHIINIGRLCL-DQHSLIPATASAVWEIIKRTGIQTFGKNVV 100
Query: 597 VLGRSRIVGTPVSELL--KWEH------ATVTVCHSKT--KNLSEITKTAEILVVAIGRP 746
V GRS+ VG P++ LL EH ATVT+ H T + L T+ A+I++VA G P
Sbjct: 101 VAGRSKNVGMPIAMLLHTDGEHERPGGDATVTIAHRYTPKEQLKIHTQLADIIIVAAGIP 160
Query: 747 EXVRGSWIKPGAVVIDCGINAIEDPTKKSGQRLXGDVAYQXAVK 878
+ + +K GA VID GIN + DP +L GDV ++ AVK
Sbjct: 161 KLITSDMVKEGAAVIDVGINYVHDPV-TGKTKLVGDVDFE-AVK 202
>AY374131-1|AAQ82697.1| 275|Homo sapiens truncated
C1-tetrahydrofolate synthase protein.
Length = 275
Score = 95.9 bits (228), Expect = 2e-19
Identities = 58/196 (29%), Positives = 106/196 (54%), Gaps = 1/196 (0%)
Frame = +3
Query: 138 IENDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYIRMKLKAAEKIGIAAEHIRLPRD 317
I+N ++ ++ L+ K F+P LAI+Q G D N+ + AE+ G+ HI LP D
Sbjct: 79 IQNS-KEVLSLLQEKNPAFKPVLAIIQAG---DDNLMQEINQNLAEEAGLNITHICLPPD 134
Query: 318 ITEIELLAKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKDVDGLNTINEGRV 497
+E E++ +I +NE VHG+ +Q+ + +++V +A+ P+KDVDG+ IN G++
Sbjct: 135 SSEAEIIDEILKINEDTRVHGLALQI----SENLFSNKVLNALKPEKDVDGVTDINLGKL 190
Query: 498 AVGDL-SGFIPCTPAGCVELIKKTGVTIAGKNVVVLGRSRIVGTPVSELLKWEHATVTVC 674
GD F+ +EL++K+GV + GK ++V+G + + L + + +
Sbjct: 191 VRGDAHECFVSPVAKAVIELLEKSGVNLDGKKILVVGAHGSLEAALQCLFQRKGSMTMSI 250
Query: 675 HSKTKNLSEITKTAEI 722
KT+ L T++ +
Sbjct: 251 QWKTRQLQSKTESRSV 266
>BC032771-1|AAH32771.1| 146|Homo sapiens MTHFD2L protein protein.
Length = 146
Score = 95.5 bits (227), Expect = 2e-19
Identities = 59/136 (43%), Positives = 83/136 (61%), Gaps = 10/136 (7%)
Frame = +3
Query: 366 PSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKDVDGLNTINEGRVAVGDLSGFIPCTPAGC 545
P V GI+VQ+PL DH +D + + ++P+KDVDG + IN GR+ + D IP T +
Sbjct: 3 PRVSGILVQLPLP-DH-VDERTICNGIAPEKDVDGFHIINIGRLCL-DQHSLIPATASAV 59
Query: 546 VELIKKTGVTIAGKNVVVLGRSRIVGTPVSELL--KWEH------ATVTVCHSKT--KNL 695
E+IK+TG+ GKNVVV GRS+ VG P++ LL EH ATVT+ H T + L
Sbjct: 60 WEIIKRTGIQTFGKNVVVAGRSKNVGMPIAMLLHTDGEHERPGGDATVTIAHRYTPKEQL 119
Query: 696 SEITKTAEILVVAIGR 743
T+ A+I++VA R
Sbjct: 120 KIHTQLADIIIVAAER 135
>AL035086-6|CAI42793.1| 114|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1-like protein.
Length = 114
Score = 74.5 bits (175), Expect = 5e-13
Identities = 38/110 (34%), Positives = 66/110 (60%), Gaps = 1/110 (0%)
Frame = +3
Query: 270 AEKIGIAAEHIRLPRDITEIELLAKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVS 449
AE+ G+ HI LP D +E E++ +I +NE VHG+ +Q+ + +++V +A+
Sbjct: 9 AEEAGLNITHICLPPDSSEAEIIDEILKINEDTRVHGLALQI----SENLFSNKVLNALK 64
Query: 450 PDKDVDGLNTINEGRVAVGDL-SGFIPCTPAGCVELIKKTGVTIAGKNVV 596
P+KDVDG+ IN G++ GD F+ +EL++K+GV + GK ++
Sbjct: 65 PEKDVDGVTDINLGKLVRGDAHECFVSPVAKAVIELLEKSGVNLDGKKIL 114
>BC037529-1|AAH37529.2| 106|Homo sapiens MTHFD2L protein protein.
Length = 106
Score = 64.1 bits (149), Expect = 7e-10
Identities = 30/68 (44%), Positives = 44/68 (64%)
Frame = +3
Query: 198 PRLAIVQVGGREDSNVYIRMKLKAAEKIGIAAEHIRLPRDITEIELLAKITSLNESPSVH 377
P L+I+ VG S+ Y+R K++AA +GI +E I P+D+++ ELL LN P V
Sbjct: 24 PHLSIILVGDNPASHTYVRNKIRAASAVGICSELILKPKDVSQEELLDVTDQLNMDPRVS 83
Query: 378 GIIVQMPL 401
GI+VQ+PL
Sbjct: 84 GILVQLPL 91
>AL035086-4|CAI42792.1| 120|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1-like protein.
Length = 120
Score = 53.6 bits (123), Expect = 1e-06
Identities = 28/101 (27%), Positives = 55/101 (54%), Gaps = 1/101 (0%)
Frame = +3
Query: 423 AHRVTDAVSPDKDVDGLNTINEGRVAVGDL-SGFIPCTPAGCVELIKKTGVTIAGKNVVV 599
+++V +A+ P+KDVDG+ IN G++ GD F+ +EL++K+GV + GK ++V
Sbjct: 11 SNKVLNALKPEKDVDGVTDINLGKLVRGDAHECFVSPVAKAVIELLEKSGVNLDGKKILV 70
Query: 600 LGRSRIVGTPVSELLKWEHATVTVCHSKTKNLSEITKTAEI 722
+G + + L + + + KT+ L T++ +
Sbjct: 71 VGAHGSLEAALQCLFQRKGSMTMSIQWKTRQLQSKTESRSV 111
>BC017477-1|AAH17477.2| 775|Homo sapiens MTHFD1L protein protein.
Length = 775
Score = 51.6 bits (118), Expect = 4e-06
Identities = 24/84 (28%), Positives = 47/84 (55%)
Frame = +3
Query: 546 VELIKKTGVTIAGKNVVVLGRSRIVGTPVSELLKWEHATVTVCHSKTKNLSEITKTAEIL 725
+EL++K+GV + GK ++V+G + + L + + + KT+ L A+I+
Sbjct: 5 IELLEKSGVNLDGKKILVVGAHGSLEAALQCLFQRKGSMTMSIQWKTRQLQSKLHEADIV 64
Query: 726 VVAIGRPEXVRGSWIKPGAVVIDC 797
V+ +PE + +WI+PG V++C
Sbjct: 65 VLGSPKPEEIPLTWIQPGTTVLNC 88
>AL035086-5|CAI42791.1| 120|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1-like protein.
Length = 120
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/102 (27%), Positives = 55/102 (53%), Gaps = 2/102 (1%)
Frame = +3
Query: 423 AHRVTDAVSPDKDVDGLNTINEGRVAVGDL-SGFIPCTPAGCVELIKKT-GVTIAGKNVV 596
+++V +A+ P+KDVDG+ IN G++ GD F+ +EL++K+ GV + GK ++
Sbjct: 10 SNKVLNALKPEKDVDGVTDINLGKLVRGDAHECFVSPVAKAVIELLEKSVGVNLDGKKIL 69
Query: 597 VLGRSRIVGTPVSELLKWEHATVTVCHSKTKNLSEITKTAEI 722
V+G + + L + + + KT+ L T++ +
Sbjct: 70 VVGAHGSLEAALQCLFQRKGSMTMSIQWKTRQLQSKTESRSV 111
>BC006399-1|AAH06399.2| 396|Homo sapiens reticulon 4 interacting
protein 1 protein.
Length = 396
Score = 33.9 bits (74), Expect = 0.85
Identities = 40/184 (21%), Positives = 68/184 (36%), Gaps = 13/184 (7%)
Frame = +3
Query: 282 GIAAEHIRLPRDITEIELLAKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKD 461
G A + + RD +++ + L V G++++ LD + V AV P K
Sbjct: 93 GYGATALNMKRDPLHVKIKGEEFPLTLGRDVSGVVMECGLDVKYFKPGDEVWAAVPPWKQ 152
Query: 462 --------VDGLNTINEGRVAVGDLSGFIPCTPAGCVELIKKTG----VTIAGKNVVVLG 605
V G ++ + + +P I K G GK V++LG
Sbjct: 153 GTLSEFVVVSGNEVSHKPKSLTHTQAASLPYVALTAWSAINKVGGLNDKNCTGKRVLILG 212
Query: 606 RSRIVGTPVSELLK-WEHATVTVCHSKTKNLSEITKTAEILVVAIGRPEXVRGSWIKPGA 782
S VGT +++K W+ VC L +++ G E S +KP
Sbjct: 213 ASGGVGTFAIQVMKAWDAHVTAVCSQDASELVRKLGADDVIDYKSGSVEEQLKS-LKPFD 271
Query: 783 VVID 794
++D
Sbjct: 272 FILD 275
>AY063761-1|AAL40856.1| 396|Homo sapiens NOGO-interacting
mitochondrial protein protein.
Length = 396
Score = 33.9 bits (74), Expect = 0.85
Identities = 40/184 (21%), Positives = 68/184 (36%), Gaps = 13/184 (7%)
Frame = +3
Query: 282 GIAAEHIRLPRDITEIELLAKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKD 461
G A + + RD +++ + L V G++++ LD + V AV P K
Sbjct: 93 GYGATALNMKRDPLHVKIKGEEFPLTLGRDVSGVVMECGLDVKYFKPGDEVWAAVPPWKQ 152
Query: 462 --------VDGLNTINEGRVAVGDLSGFIPCTPAGCVELIKKTG----VTIAGKNVVVLG 605
V G ++ + + +P I K G GK V++LG
Sbjct: 153 GTLSEFVVVSGNEVSHKPKSLTHTQAASLPYVALTAWSAINKVGGLNDKNCTGKRVLILG 212
Query: 606 RSRIVGTPVSELLK-WEHATVTVCHSKTKNLSEITKTAEILVVAIGRPEXVRGSWIKPGA 782
S VGT +++K W+ VC L +++ G E S +KP
Sbjct: 213 ASGGVGTFAIQVMKAWDAHVTAVCSQDASELVRKLGADDVIDYKSGSVEEQLKS-LKPFD 271
Query: 783 VVID 794
++D
Sbjct: 272 FILD 275
>AL390074-5|CAH72095.1| 396|Homo sapiens reticulon 4 interacting
protein 1 protein.
Length = 396
Score = 33.9 bits (74), Expect = 0.85
Identities = 40/184 (21%), Positives = 68/184 (36%), Gaps = 13/184 (7%)
Frame = +3
Query: 282 GIAAEHIRLPRDITEIELLAKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKD 461
G A + + RD +++ + L V G++++ LD + V AV P K
Sbjct: 93 GYGATALNMKRDPLHVKIKGEEFPLTLGRDVSGVVMECGLDVKYFKPGDEVWAAVPPWKQ 152
Query: 462 --------VDGLNTINEGRVAVGDLSGFIPCTPAGCVELIKKTG----VTIAGKNVVVLG 605
V G ++ + + +P I K G GK V++LG
Sbjct: 153 GTLSEFVVVSGNEVSHKPKSLTHTQAASLPYVALTAWSAINKVGGLNDKNCTGKRVLILG 212
Query: 606 RSRIVGTPVSELLK-WEHATVTVCHSKTKNLSEITKTAEILVVAIGRPEXVRGSWIKPGA 782
S VGT +++K W+ VC L +++ G E S +KP
Sbjct: 213 ASGGVGTFAIQVMKAWDAHVTAVCSQDASELVRKLGADDVIDYKSGSVEEQLKS-LKPFD 271
Query: 783 VVID 794
++D
Sbjct: 272 FILD 275
>BC065771-1|AAH65771.1| 70|Homo sapiens MTHFD2L protein protein.
Length = 70
Score = 32.7 bits (71), Expect = 2.0
Identities = 18/37 (48%), Positives = 23/37 (62%)
Frame = +3
Query: 768 IKPGAVVIDCGINAIEDPTKKSGQRLXGDVAYQXAVK 878
+K GA VID GIN + DP +L GDV ++ AVK
Sbjct: 2 VKEGAAVIDVGINYVHDPV-TGKTKLVGDVDFE-AVK 36
>AF336861-1|AAK64603.1| 396|Homo sapiens NOGO-interacting
mitochondrial protein protein.
Length = 396
Score = 31.5 bits (68), Expect = 4.5
Identities = 32/144 (22%), Positives = 55/144 (38%), Gaps = 13/144 (9%)
Frame = +3
Query: 282 GIAAEHIRLPRDITEIELLAKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKD 461
G A + + RD +++ + L V G++++ LD + V AV P K
Sbjct: 93 GYGATALNMKRDPLHVKIKGEEFPLTLGRDVSGVVMECGLDVKYFKPGDEVWAAVPPWKQ 152
Query: 462 --------VDGLNTINEGRVAVGDLSGFIPCTPAGCVELIKKTG----VTIAGKNVVVLG 605
V G ++ + + +P I K G GK V++LG
Sbjct: 153 GTLSEFVVVSGNEVSHKPKSLTHTQAASLPYVALTAWSAINKVGGLNDKNCTGKRVLILG 212
Query: 606 RSRIVGTPVSELLK-WEHATVTVC 674
S +GT +++K W+ VC
Sbjct: 213 ASGGIGTFAIQVMKAWDAHVTAVC 236
>AK131318-1|BAD18481.1| 276|Homo sapiens protein ( Homo sapiens
cDNA FLJ16314 fis, clone SPLEN2030847, highly similar
to Mus musculus Kif21b (Kif21b) mRNA. ).
Length = 276
Score = 31.1 bits (67), Expect = 6.0
Identities = 36/124 (29%), Positives = 49/124 (39%)
Frame = -3
Query: 814 SIALIPQSITTAPGLIQEPRTISGRPIATTSISAVLVISLKFLVFEWHTVTVACSHFSNS 635
+I L + T P L+ E ++G P T S ++ KF H V +A S
Sbjct: 13 TIHLCQMRMCTQPDLVNE--AVTGLPDGTPPSSEYETLTAKF-----HFVDLAGSERLKR 65
Query: 634 DTGVPTMRLRPSTTTFLPAIVTPVFLMSSTHPAGVQGINPDRSPTATRPSLIVFKPSTSL 455
TG R + + + T + STH A Q SPT SL + S SL
Sbjct: 66 -TGATGERAKEGISINCGLVGTWWVISPSTHTAQSQTPPRPCSPTPAESSLDILPISPSL 124
Query: 454 SGET 443
SG T
Sbjct: 125 SGVT 128
>AK095207-1|BAC04499.1| 296|Homo sapiens protein ( Homo sapiens
cDNA FLJ37888 fis, clone BRTHA2000474. ).
Length = 296
Score = 31.1 bits (67), Expect = 6.0
Identities = 38/176 (21%), Positives = 65/176 (36%), Gaps = 13/176 (7%)
Frame = +3
Query: 306 LPRDITEIELLAKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKD-------- 461
+ RD +++ + L V G++++ LD + V AV P K
Sbjct: 1 MKRDPLHVKIKGEEFPLTLGRDVSGVVMECGLDVKYFKPGDEVWAAVPPWKQGTLSEFVV 60
Query: 462 VDGLNTINEGRVAVGDLSGFIPCTPAGCVELIKKTG----VTIAGKNVVVLGRSRIVGTP 629
V G ++ + + +P I K G GK V++LG S VGT
Sbjct: 61 VSGSEVSHKPKSLTHTQAASLPYVALTAWSAINKVGGLNDKNCTGKRVLILGASGGVGTF 120
Query: 630 VSELLK-WEHATVTVCHSKTKNLSEITKTAEILVVAIGRPEXVRGSWIKPGAVVID 794
+++K W+ VC L +++ G E S +KP ++D
Sbjct: 121 AIQVMKAWDAHVTAVCSQDASELVRKLGADDVIDYKSGSVEEQLKS-LKPFDFILD 175
>BC016821-1|AAH16821.1| 343|Homo sapiens MAP3K12 binding inhibitory
protein 1 protein.
Length = 343
Score = 30.7 bits (66), Expect = 7.9
Identities = 12/26 (46%), Positives = 18/26 (69%)
Frame = +3
Query: 741 RPEXVRGSWIKPGAVVIDCGINAIED 818
RPE + GS KP +++ DCG A+E+
Sbjct: 225 RPEGIPGSGHKPNSMLRDCGNQAVEE 250
>BC005197-1|AAH05197.1| 344|Homo sapiens MAP3K12 binding inhibitory
protein 1 protein.
Length = 344
Score = 30.7 bits (66), Expect = 7.9
Identities = 12/26 (46%), Positives = 18/26 (69%)
Frame = +3
Query: 741 RPEXVRGSWIKPGAVVIDCGINAIED 818
RPE + GS KP +++ DCG A+E+
Sbjct: 225 RPEGIPGSGHKPNSMLRDCGNQAVEE 250
>AB038523-1|BAA94083.1| 344|Homo sapiens MBIP protein.
Length = 344
Score = 30.7 bits (66), Expect = 7.9
Identities = 12/26 (46%), Positives = 18/26 (69%)
Frame = +3
Query: 741 RPEXVRGSWIKPGAVVIDCGINAIED 818
RPE + GS KP +++ DCG A+E+
Sbjct: 225 RPEGIPGSGHKPNSMLRDCGNQAVEE 250
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 130,297,906
Number of Sequences: 237096
Number of extensions: 2672417
Number of successful extensions: 7594
Number of sequences better than 10.0: 37
Number of HSP's better than 10.0 without gapping: 7183
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7513
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 12214492840
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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