Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP20_F_O05
(897 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC026179-1|AAH26179.1| 418|Homo sapiens SEC61A2 protein protein. 316 7e-86
AF346603-1|AAK29084.1| 476|Homo sapiens Sec61 alpha form 2 prot... 316 7e-86
AK022640-1|BAB14148.1| 437|Homo sapiens protein ( Homo sapiens ... 314 2e-85
AF346602-1|AAK29083.1| 476|Homo sapiens Sec61 alpha form 1 prot... 311 3e-84
AF084458-1|AAD39847.1| 476|Homo sapiens sec61 homolog protein. 311 3e-84
AK074928-1|BAC11298.1| 356|Homo sapiens protein ( Homo sapiens ... 265 2e-70
AK022027-1|BAB13955.1| 234|Homo sapiens protein ( Homo sapiens ... 157 4e-38
AK001440-1|BAA91692.1| 234|Homo sapiens protein ( Homo sapiens ... 157 4e-38
AL831940-1|CAD38592.1| 215|Homo sapiens hypothetical protein pr... 144 5e-34
AK075148-1|BAC11434.1| 170|Homo sapiens protein ( Homo sapiens ... 57 1e-07
AK074907-1|BAC11283.1| 170|Homo sapiens protein ( Homo sapiens ... 57 1e-07
U63623-1|AAB26958.1| 301|Homo sapiens aquaporin 4 protein. 33 1.1
U63622-1|AAB26957.1| 323|Homo sapiens aquaporin 4 protein. 33 1.1
U34846-1|AAC52112.1| 341|Homo sapiens mercurial-insensitive wat... 33 1.1
U34845-1|AAC50284.1| 301|Homo sapiens mercurial-insensitive wat... 33 1.1
D63412-1|BAA09715.1| 323|Homo sapiens aquaporin protein. 33 1.1
BC022286-1|AAH22286.1| 323|Homo sapiens aquaporin 4 protein. 33 1.1
AK222684-1|BAD96404.1| 323|Homo sapiens aquaporin 4 isoform a v... 33 1.1
BC139906-1|AAI39907.1| 450|Homo sapiens hypothetical protein LO... 31 4.3
AY358345-1|AAQ88711.1| 450|Homo sapiens WLKV305 protein. 31 4.3
AB128929-1|BAD22823.1| 218|Homo sapiens aquaporin type4 transcr... 30 9.9
>BC026179-1|AAH26179.1| 418|Homo sapiens SEC61A2 protein protein.
Length = 418
Score = 316 bits (776), Expect = 7e-86
Identities = 157/195 (80%), Positives = 170/195 (87%), Gaps = 7/195 (3%)
Frame = +1
Query: 70 KSFEVGDTPKDRALFNGAQKLFGMVITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFV 249
K EVGDTPKDRALFNGAQKLFGM+IT+GQAIVYVMTGMYG+P+E+GAG+CLLIIIQLFV
Sbjct: 98 KIIEVGDTPKDRALFNGAQKLFGMIITIGQAIVYVMTGMYGDPAEMGAGICLLIIIQLFV 157
Query: 250 AGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPATVNTGRGTEFEGAVIALF 429
AGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSP T+NTGRGTEFEGAVIALF
Sbjct: 158 AGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTINTGRGTEFEGAVIALF 217
Query: 430 HLLATRPDKVRALREAFYRQNLPNLMNLLATVLVFAIVIYFQG----LP---CRFAHQVC 588
HLLATR DKVRALREAFYRQNLPNLMNL+ATV VFA+VIYFQG LP R+ Q
Sbjct: 218 HLLATRTDKVRALREAFYRQNLPNLMNLIATVFVFAVVIYFQGFRVDLPIKSARYRGQYS 277
Query: 589 SLSWTVFFIPNQTIL 633
S +F+ N I+
Sbjct: 278 SYPIKLFYTSNIPII 292
Score = 157 bits (382), Expect = 4e-38
Identities = 74/86 (86%), Positives = 77/86 (89%)
Frame = +2
Query: 560 FRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAVKFXGNFLXNV 739
FRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQML+V+F GNFL N+
Sbjct: 261 FRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSVRFSGNFLVNL 320
Query: 740 LGVWADXGGGXPAXXAPVGGLCYYLS 817
LG WAD GG PA PVGGLCYYLS
Sbjct: 321 LGQWADVSGGGPARSYPVGGLCYYLS 346
>AF346603-1|AAK29084.1| 476|Homo sapiens Sec61 alpha form 2
protein.
Length = 476
Score = 316 bits (776), Expect = 7e-86
Identities = 157/195 (80%), Positives = 170/195 (87%), Gaps = 7/195 (3%)
Frame = +1
Query: 70 KSFEVGDTPKDRALFNGAQKLFGMVITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFV 249
K EVGDTPKDRALFNGAQKLFGM+IT+GQAIVYVMTGMYG+P+E+GAG+CLLIIIQLFV
Sbjct: 98 KIIEVGDTPKDRALFNGAQKLFGMIITIGQAIVYVMTGMYGDPAEMGAGICLLIIIQLFV 157
Query: 250 AGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPATVNTGRGTEFEGAVIALF 429
AGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSP T+NTGRGTEFEGAVIALF
Sbjct: 158 AGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTINTGRGTEFEGAVIALF 217
Query: 430 HLLATRPDKVRALREAFYRQNLPNLMNLLATVLVFAIVIYFQG----LP---CRFAHQVC 588
HLLATR DKVRALREAFYRQNLPNLMNL+ATV VFA+VIYFQG LP R+ Q
Sbjct: 218 HLLATRTDKVRALREAFYRQNLPNLMNLIATVFVFAVVIYFQGFRVDLPIKSARYRGQYS 277
Query: 589 SLSWTVFFIPNQTIL 633
S +F+ N I+
Sbjct: 278 SYPIKLFYTSNIPII 292
Score = 157 bits (382), Expect = 4e-38
Identities = 74/86 (86%), Positives = 77/86 (89%)
Frame = +2
Query: 560 FRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAVKFXGNFLXNV 739
FRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQML+V+F GNFL N+
Sbjct: 261 FRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSVRFSGNFLVNL 320
Query: 740 LGVWADXGGGXPAXXAPVGGLCYYLS 817
LG WAD GG PA PVGGLCYYLS
Sbjct: 321 LGQWADVSGGGPARSYPVGGLCYYLS 346
>AK022640-1|BAB14148.1| 437|Homo sapiens protein ( Homo sapiens
cDNA FLJ12578 fis, clone NT2RM4001054, moderately
similar to Homo sapiens sec61 homolog mRNA. ).
Length = 437
Score = 314 bits (772), Expect = 2e-85
Identities = 156/195 (80%), Positives = 170/195 (87%), Gaps = 7/195 (3%)
Frame = +1
Query: 70 KSFEVGDTPKDRALFNGAQKLFGMVITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFV 249
K EVGDTPKDRALFNGAQKLFGM+IT+GQAIVYV+TGMYG+P+E+GAG+CLLIIIQLFV
Sbjct: 98 KIIEVGDTPKDRALFNGAQKLFGMIITIGQAIVYVITGMYGDPAEMGAGICLLIIIQLFV 157
Query: 250 AGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPATVNTGRGTEFEGAVIALF 429
AGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSP T+NTGRGTEFEGAVIALF
Sbjct: 158 AGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTINTGRGTEFEGAVIALF 217
Query: 430 HLLATRPDKVRALREAFYRQNLPNLMNLLATVLVFAIVIYFQG----LP---CRFAHQVC 588
HLLATR DKVRALREAFYRQNLPNLMNL+ATV VFA+VIYFQG LP R+ Q
Sbjct: 218 HLLATRTDKVRALREAFYRQNLPNLMNLIATVFVFAVVIYFQGFRVDLPIKSARYRGQYS 277
Query: 589 SLSWTVFFIPNQTIL 633
S +F+ N I+
Sbjct: 278 SYPIKLFYTSNIPII 292
Score = 157 bits (382), Expect = 4e-38
Identities = 74/86 (86%), Positives = 77/86 (89%)
Frame = +2
Query: 560 FRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAVKFXGNFLXNV 739
FRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQML+V+F GNFL N+
Sbjct: 261 FRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSVRFSGNFLVNL 320
Query: 740 LGVWADXGGGXPAXXAPVGGLCYYLS 817
LG WAD GG PA PVGGLCYYLS
Sbjct: 321 LGQWADVSGGGPARSYPVGGLCYYLS 346
>AF346602-1|AAK29083.1| 476|Homo sapiens Sec61 alpha form 1
protein.
Length = 476
Score = 311 bits (763), Expect = 3e-84
Identities = 146/163 (89%), Positives = 156/163 (95%)
Frame = +1
Query: 70 KSFEVGDTPKDRALFNGAQKLFGMVITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFV 249
K EVGDTPKDRALFNGAQKLFGM+IT+GQ+IVYVMTGMYG+PSE+GAG+CLLI IQLFV
Sbjct: 98 KIIEVGDTPKDRALFNGAQKLFGMIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFV 157
Query: 250 AGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPATVNTGRGTEFEGAVIALF 429
AGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSP TVNTGRG EFEGA+IALF
Sbjct: 158 AGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVNTGRGMEFEGAIIALF 217
Query: 430 HLLATRPDKVRALREAFYRQNLPNLMNLLATVLVFAIVIYFQG 558
HLLATR DKVRALREAFYRQNLPNLMNL+AT+ VFA+VIYFQG
Sbjct: 218 HLLATRTDKVRALREAFYRQNLPNLMNLIATIFVFAVVIYFQG 260
Score = 146 bits (354), Expect = 1e-34
Identities = 67/86 (77%), Positives = 74/86 (86%)
Frame = +2
Query: 560 FRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAVKFXGNFLXNV 739
FRVDLPIKSARYRGQY++YPIKLFYTSNIPIILQSALVSNLYVISQML+ +F GN L ++
Sbjct: 261 FRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSARFSGNLLVSL 320
Query: 740 LGVWADXGGGXPAXXAPVGGLCYYLS 817
LG W+D G PA PVGGLCYYLS
Sbjct: 321 LGTWSDTSSGGPARAYPVGGLCYYLS 346
>AF084458-1|AAD39847.1| 476|Homo sapiens sec61 homolog protein.
Length = 476
Score = 311 bits (763), Expect = 3e-84
Identities = 146/163 (89%), Positives = 156/163 (95%)
Frame = +1
Query: 70 KSFEVGDTPKDRALFNGAQKLFGMVITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFV 249
K EVGDTPKDRALFNGAQKLFGM+IT+GQ+IVYVMTGMYG+PSE+GAG+CLLI IQLFV
Sbjct: 98 KIIEVGDTPKDRALFNGAQKLFGMIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFV 157
Query: 250 AGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPATVNTGRGTEFEGAVIALF 429
AGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSP TVNTGRG EFEGA+IALF
Sbjct: 158 AGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVNTGRGMEFEGAIIALF 217
Query: 430 HLLATRPDKVRALREAFYRQNLPNLMNLLATVLVFAIVIYFQG 558
HLLATR DKVRALREAFYRQNLPNLMNL+AT+ VFA+VIYFQG
Sbjct: 218 HLLATRTDKVRALREAFYRQNLPNLMNLIATIFVFAVVIYFQG 260
Score = 146 bits (354), Expect = 1e-34
Identities = 67/86 (77%), Positives = 74/86 (86%)
Frame = +2
Query: 560 FRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAVKFXGNFLXNV 739
FRVDLPIKSARYRGQY++YPIKLFYTSNIPIILQSALVSNLYVISQML+ +F GN L ++
Sbjct: 261 FRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSARFSGNLLVSL 320
Query: 740 LGVWADXGGGXPAXXAPVGGLCYYLS 817
LG W+D G PA PVGGLCYYLS
Sbjct: 321 LGTWSDTSSGGPARAYPVGGLCYYLS 346
>AK074928-1|BAC11298.1| 356|Homo sapiens protein ( Homo sapiens
cDNA FLJ90447 fis, clone NT2RP3001240, highly similar to
Canis familiaris sec61 homologue mRNA. ).
Length = 356
Score = 265 bits (649), Expect = 2e-70
Identities = 124/140 (88%), Positives = 134/140 (95%)
Frame = +1
Query: 139 MVITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSGIS 318
M+IT+GQ+IVYVMTGMYG+PSE+GAG+CLLI IQLFVAGLIVLLLDELLQKGYGLGSGIS
Sbjct: 1 MIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGIS 60
Query: 319 LFIATNICETIVWKAFSPATVNTGRGTEFEGAVIALFHLLATRPDKVRALREAFYRQNLP 498
LFIATNICETIVWKAFSP TVNTGRG EFEGA+IALFHLLATR DKVRALREA YRQNLP
Sbjct: 61 LFIATNICETIVWKAFSPTTVNTGRGMEFEGAIIALFHLLATRTDKVRALREALYRQNLP 120
Query: 499 NLMNLLATVLVFAIVIYFQG 558
NLMNL+AT+ VFA+VIYFQG
Sbjct: 121 NLMNLIATIFVFAVVIYFQG 140
Score = 146 bits (354), Expect = 1e-34
Identities = 67/86 (77%), Positives = 74/86 (86%)
Frame = +2
Query: 560 FRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAVKFXGNFLXNV 739
FRVDLPIKSARYRGQY++YPIKLFYTSNIPIILQSALVSNLYVISQML+ +F GN L ++
Sbjct: 141 FRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSARFSGNLLVSL 200
Query: 740 LGVWADXGGGXPAXXAPVGGLCYYLS 817
LG W+D G PA PVGGLCYYLS
Sbjct: 201 LGTWSDTSSGGPARAYPVGGLCYYLS 226
>AK022027-1|BAB13955.1| 234|Homo sapiens protein ( Homo sapiens
cDNA FLJ11965 fis, clone HEMBB1001112, moderately
similar to Homo sapiens sec61 homolog mRNA. ).
Length = 234
Score = 157 bits (382), Expect = 4e-38
Identities = 74/86 (86%), Positives = 77/86 (89%)
Frame = +2
Query: 560 FRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAVKFXGNFLXNV 739
FRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQML+V+F GNFL N+
Sbjct: 19 FRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSVRFSGNFLVNL 78
Query: 740 LGVWADXGGGXPAXXAPVGGLCYYLS 817
LG WAD GG PA PVGGLCYYLS
Sbjct: 79 LGQWADVSGGGPARSYPVGGLCYYLS 104
Score = 36.3 bits (80), Expect = 0.15
Identities = 23/50 (46%), Positives = 29/50 (58%), Gaps = 7/50 (14%)
Frame = +1
Query: 505 MNLLATVLVFAIVIYFQG----LP---CRFAHQVCSLSWTVFFIPNQTIL 633
MNL+ATV VFA+VIYFQG LP R+ Q S +F+ N I+
Sbjct: 1 MNLIATVFVFAVVIYFQGFRVDLPIKSARYRGQYSSYPIKLFYTSNIPII 50
>AK001440-1|BAA91692.1| 234|Homo sapiens protein ( Homo sapiens
cDNA FLJ10578 fis, clone NT2RP2003433, highly similar to
PROTEIN TRANSPORT PROTEIN SEC61 ALPHA SUBUNIT. ).
Length = 234
Score = 157 bits (382), Expect = 4e-38
Identities = 74/86 (86%), Positives = 77/86 (89%)
Frame = +2
Query: 560 FRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAVKFXGNFLXNV 739
FRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQML+V+F GNFL N+
Sbjct: 19 FRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSVRFSGNFLVNL 78
Query: 740 LGVWADXGGGXPAXXAPVGGLCYYLS 817
LG WAD GG PA PVGGLCYYLS
Sbjct: 79 LGQWADVSGGGPARSYPVGGLCYYLS 104
Score = 36.3 bits (80), Expect = 0.15
Identities = 23/50 (46%), Positives = 29/50 (58%), Gaps = 7/50 (14%)
Frame = +1
Query: 505 MNLLATVLVFAIVIYFQG----LP---CRFAHQVCSLSWTVFFIPNQTIL 633
MNL+ATV VFA+VIYFQG LP R+ Q S +F+ N I+
Sbjct: 1 MNLIATVFVFAVVIYFQGFRVDLPIKSARYRGQYSSYPIKLFYTSNIPII 50
>AL831940-1|CAD38592.1| 215|Homo sapiens hypothetical protein
protein.
Length = 215
Score = 144 bits (348), Expect = 5e-34
Identities = 66/85 (77%), Positives = 73/85 (85%)
Frame = +2
Query: 563 RVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLAVKFXGNFLXNVL 742
RVDLPIKSARYRGQY++YPIKLFYTSNIPIILQSALVSNLYVISQML+ +F GN L ++L
Sbjct: 1 RVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSARFSGNLLVSLL 60
Query: 743 GVWADXGGGXPAXXAPVGGLCYYLS 817
G W+D G PA PVGGLCYYLS
Sbjct: 61 GTWSDTSSGGPARAYPVGGLCYYLS 85
>AK075148-1|BAC11434.1| 170|Homo sapiens protein ( Homo sapiens
cDNA FLJ90667 fis, clone PLACE1005410, highly similar to
Protein transport protein Sec61 alpha subunitisoform 1.
).
Length = 170
Score = 56.8 bits (131), Expect = 1e-07
Identities = 23/40 (57%), Positives = 28/40 (70%)
Frame = +2
Query: 698 MLAVKFXGNFLXNVLGVWADXGGGXPAXXAPVGGLCYYLS 817
ML+ +F GN L ++LG W+D G PA PVGGLCYYLS
Sbjct: 1 MLSARFSGNLLVSLLGTWSDTSSGGPARAYPVGGLCYYLS 40
>AK074907-1|BAC11283.1| 170|Homo sapiens protein ( Homo sapiens
cDNA FLJ90426 fis, clone NT2RP3000460, highly similar to
Protein transport protein Sec61 alpha subunitisoform 1.
).
Length = 170
Score = 56.8 bits (131), Expect = 1e-07
Identities = 23/40 (57%), Positives = 28/40 (70%)
Frame = +2
Query: 698 MLAVKFXGNFLXNVLGVWADXGGGXPAXXAPVGGLCYYLS 817
ML+ +F GN L ++LG W+D G PA PVGGLCYYLS
Sbjct: 1 MLSARFSGNLLVSLLGTWSDTSSGGPARAYPVGGLCYYLS 40
>U63623-1|AAB26958.1| 301|Homo sapiens aquaporin 4 protein.
Length = 301
Score = 33.5 bits (73), Expect = 1.1
Identities = 29/99 (29%), Positives = 45/99 (45%)
Frame = +1
Query: 145 ITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLF 324
I++ +++ Y+ G + IGAG+ L+ V GL V ++ L G+GL + L
Sbjct: 88 ISIAKSVFYIAAQCLG--AIIGAGILYLVTPPSVVGGLGVTMVHGNLTAGHGL--LVELI 143
Query: 325 IATNICETIVWKAFSPATVNTGRGTEFEGAVIALFHLLA 441
I + TI S T TG G +A+ HL A
Sbjct: 144 ITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAIGHLFA 182
>U63622-1|AAB26957.1| 323|Homo sapiens aquaporin 4 protein.
Length = 323
Score = 33.5 bits (73), Expect = 1.1
Identities = 29/99 (29%), Positives = 45/99 (45%)
Frame = +1
Query: 145 ITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLF 324
I++ +++ Y+ G + IGAG+ L+ V GL V ++ L G+GL + L
Sbjct: 110 ISIAKSVFYIAAQCLG--AIIGAGILYLVTPPSVVGGLGVTMVHGNLTAGHGL--LVELI 165
Query: 325 IATNICETIVWKAFSPATVNTGRGTEFEGAVIALFHLLA 441
I + TI S T TG G +A+ HL A
Sbjct: 166 ITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAIGHLFA 204
>U34846-1|AAC52112.1| 341|Homo sapiens mercurial-insensitive water
channel protein.
Length = 341
Score = 33.5 bits (73), Expect = 1.1
Identities = 29/99 (29%), Positives = 45/99 (45%)
Frame = +1
Query: 145 ITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLF 324
I++ +++ Y+ G + IGAG+ L+ V GL V ++ L G+GL + L
Sbjct: 128 ISIAKSVFYIAAQCLG--AIIGAGILYLVTPPSVVGGLGVTMVHGNLTAGHGL--LVELI 183
Query: 325 IATNICETIVWKAFSPATVNTGRGTEFEGAVIALFHLLA 441
I + TI S T TG G +A+ HL A
Sbjct: 184 ITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAIGHLFA 222
>U34845-1|AAC50284.1| 301|Homo sapiens mercurial-insensitive water
channel protein.
Length = 301
Score = 33.5 bits (73), Expect = 1.1
Identities = 29/99 (29%), Positives = 45/99 (45%)
Frame = +1
Query: 145 ITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLF 324
I++ +++ Y+ G + IGAG+ L+ V GL V ++ L G+GL + L
Sbjct: 88 ISIAKSVFYIAAQCLG--AIIGAGILYLVTPPSVVGGLGVTMVHGNLTAGHGL--LVELI 143
Query: 325 IATNICETIVWKAFSPATVNTGRGTEFEGAVIALFHLLA 441
I + TI S T TG G +A+ HL A
Sbjct: 144 ITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAIGHLFA 182
>D63412-1|BAA09715.1| 323|Homo sapiens aquaporin protein.
Length = 323
Score = 33.5 bits (73), Expect = 1.1
Identities = 29/99 (29%), Positives = 45/99 (45%)
Frame = +1
Query: 145 ITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLF 324
I++ +++ Y+ G + IGAG+ L+ V GL V ++ L G+GL + L
Sbjct: 110 ISIAKSVFYIAAQCLG--AIIGAGILYLVTPPSVVGGLGVTMVHGNLTAGHGL--LVELI 165
Query: 325 IATNICETIVWKAFSPATVNTGRGTEFEGAVIALFHLLA 441
I + TI S T TG G +A+ HL A
Sbjct: 166 ITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAIGHLFA 204
>BC022286-1|AAH22286.1| 323|Homo sapiens aquaporin 4 protein.
Length = 323
Score = 33.5 bits (73), Expect = 1.1
Identities = 29/99 (29%), Positives = 45/99 (45%)
Frame = +1
Query: 145 ITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLF 324
I++ +++ Y+ G + IGAG+ L+ V GL V ++ L G+GL + L
Sbjct: 110 ISIAKSVFYIAAQCLG--AIIGAGILYLVTPPSVVGGLGVTMVHGNLTAGHGL--LVELI 165
Query: 325 IATNICETIVWKAFSPATVNTGRGTEFEGAVIALFHLLA 441
I + TI S T TG G +A+ HL A
Sbjct: 166 ITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAIGHLFA 204
>AK222684-1|BAD96404.1| 323|Homo sapiens aquaporin 4 isoform a
variant protein.
Length = 323
Score = 33.5 bits (73), Expect = 1.1
Identities = 29/99 (29%), Positives = 45/99 (45%)
Frame = +1
Query: 145 ITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLF 324
I++ +++ Y+ G + IGAG+ L+ V GL V ++ L G+GL + L
Sbjct: 110 ISIAKSVFYIAAQCLG--AIIGAGILYLVTPPSVVGGLGVTMVHGNLTAGHGL--LVELI 165
Query: 325 IATNICETIVWKAFSPATVNTGRGTEFEGAVIALFHLLA 441
I + TI S T TG G +A+ HL A
Sbjct: 166 ITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAIGHLFA 204
>BC139906-1|AAI39907.1| 450|Homo sapiens hypothetical protein
LOC253012 protein.
Length = 450
Score = 31.5 bits (68), Expect = 4.3
Identities = 16/42 (38%), Positives = 24/42 (57%), Gaps = 5/42 (11%)
Frame = +1
Query: 271 LDELLQKGYGLG-----SGISLFIATNICETIVWKAFSPATV 381
L++L QKG L +GISLF+ ++C +WK + P V
Sbjct: 327 LEKLAQKGKSLSPLASITGISLFLIISMCLLFLWKKYQPYKV 368
>AY358345-1|AAQ88711.1| 450|Homo sapiens WLKV305 protein.
Length = 450
Score = 31.5 bits (68), Expect = 4.3
Identities = 16/42 (38%), Positives = 24/42 (57%), Gaps = 5/42 (11%)
Frame = +1
Query: 271 LDELLQKGYGLG-----SGISLFIATNICETIVWKAFSPATV 381
L++L QKG L +GISLF+ ++C +WK + P V
Sbjct: 327 LEKLAQKGKSLSPLASITGISLFLIISMCLLFLWKKYQPYKV 368
>AB128929-1|BAD22823.1| 218|Homo sapiens aquaporin type4 transcript
variant c protein.
Length = 218
Score = 30.3 bits (65), Expect = 9.9
Identities = 26/79 (32%), Positives = 35/79 (44%)
Frame = +1
Query: 205 IGAGVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPATVN 384
IGAG+ L+ V GL V ++ L G+GL + L I + TI S T
Sbjct: 23 IGAGILYLVTPPSVVGGLGVTMVHGNLTAGHGL--LVELIITFQLVFTIFASCDSKRTDV 80
Query: 385 TGRGTEFEGAVIALFHLLA 441
TG G +A+ HL A
Sbjct: 81 TGSIALAIGFSVAIGHLFA 99
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 129,086,651
Number of Sequences: 237096
Number of extensions: 3078885
Number of successful extensions: 6553
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 6209
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6547
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11548247776
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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