Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP20_F_N10
(899 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family... 130 7e-30
AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2 pro... 130 7e-30
AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens ... 130 7e-30
AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens ... 124 3e-28
BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family... 94 5e-19
AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein. 94 5e-19
AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform... 94 5e-19
AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein. 94 5e-19
AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein. 94 5e-19
AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein. 93 1e-18
U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein. 90 1e-17
D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4 omega-hydr... 90 1e-17
D12621-1|BAA02145.1| 389|Homo sapiens cytochrome P-450LTBV prot... 90 1e-17
D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV prot... 90 1e-17
BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family... 90 1e-17
BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family... 90 1e-17
AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family... 90 1e-17
AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfam... 90 1e-17
AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein. 90 1e-17
AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4 omega-hy... 90 1e-17
AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4 omega-hy... 90 1e-17
AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4 omega-hy... 90 1e-17
BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family... 89 2e-17
AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein. 87 6e-17
AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein. 87 6e-17
BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein. 87 8e-17
AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein. 87 8e-17
BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family... 86 2e-16
BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family... 86 2e-16
BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family... 86 2e-16
X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for ... 84 8e-16
DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family... 84 8e-16
BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family... 84 8e-16
AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P4... 84 8e-16
AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein. 84 8e-16
AY064484-1|AAL57719.1| 295|Homo sapiens truncated cytochrome P4... 84 8e-16
AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family... 84 8e-16
AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family... 84 8e-16
AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family... 84 8e-16
AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family... 84 8e-16
AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens ... 84 8e-16
AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein. 84 8e-16
AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein. 83 1e-15
J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung cyto... 82 2e-15
AF221943-1|AAF86378.1| 175|Homo sapiens leukotriene B4 omega hy... 79 2e-14
S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxyl... 78 4e-14
S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxyl... 78 4e-14
L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein. 78 4e-14
D26481-1|BAA05491.1| 519|Homo sapiens fatty acids omega-hydroxy... 78 4e-14
D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxyl... 78 4e-14
BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein. 78 4e-14
AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family... 78 4e-14
AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family... 78 4e-14
AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family... 78 4e-14
AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfam... 78 4e-14
BC022851-1|AAH22851.1| 215|Homo sapiens CYP4A11 protein protein. 77 1e-13
BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family... 74 6e-13
AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein. 74 6e-13
AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22 pr... 74 6e-13
AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein. 74 6e-13
AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family... 74 6e-13
AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens ... 74 6e-13
BC142607-1|AAI42608.1| 455|Homo sapiens CYP4A22 protein protein. 74 8e-13
AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K p... 74 8e-13
AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, famil... 72 3e-12
AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family... 72 3e-12
BC142690-1|AAI42691.1| 357|Homo sapiens CYP4A22 protein protein. 71 6e-12
AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid omega-hydrox... 71 8e-12
AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, famil... 70 1e-11
AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens ... 70 1e-11
AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens ... 69 2e-11
AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein. 69 3e-11
AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein. 69 3e-11
AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family... 69 3e-11
AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family... 69 3e-11
AK097373-1|BAC05026.1| 340|Homo sapiens protein ( Homo sapiens ... 69 3e-11
AY696295-1|AAU10524.1| 292|Homo sapiens cytochrome P450 protein. 66 2e-10
AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P4... 64 9e-10
AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family... 64 9e-10
AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family... 64 9e-10
J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipin... 61 5e-09
AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. 61 6e-09
X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for ... 60 8e-09
M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA... 60 8e-09
M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrom... 60 8e-09
DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family ... 60 8e-09
DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family... 60 8e-09
BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfam... 60 8e-09
BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family... 60 8e-09
AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypep... 60 8e-09
AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 p... 60 8e-09
AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 pro... 60 8e-09
M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glu... 59 2e-08
D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. 59 2e-08
AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43... 58 4e-08
AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43... 58 4e-08
AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfami... 58 4e-08
AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43... 58 4e-08
AF280111-1|AAG33012.1| 250|Homo sapiens cytochrome P450 subfami... 58 4e-08
AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfami... 58 4e-08
AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfami... 58 4e-08
AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfami... 58 4e-08
AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein. 58 4e-08
AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein. 58 4e-08
X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mR... 56 2e-07
D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa pro... 56 2e-07
BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family... 56 2e-07
BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family... 56 2e-07
AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant... 56 2e-07
AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450 polypep... 56 2e-07
J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 prot... 53 2e-06
DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P4... 53 2e-06
BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family... 53 2e-06
AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. 53 2e-06
M29873-1|AAA52143.1| 377|Homo sapiens CYP2B protein. 52 2e-06
BC041174-1|AAH41174.1| 377|Homo sapiens CYP2B7P1 protein protein. 52 2e-06
AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family... 52 2e-06
X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for ... 52 4e-06
U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein. 52 4e-06
M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein. 52 4e-06
M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein. 52 4e-06
DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family... 52 4e-06
BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family... 52 4e-06
BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family... 52 4e-06
BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family... 52 4e-06
BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family... 52 4e-06
AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6 pro... 52 4e-06
AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6 pro... 52 4e-06
AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein. 52 4e-06
U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein. 51 5e-06
U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein. 51 5e-06
BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family... 51 5e-06
AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13 va... 51 5e-06
AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13 va... 51 5e-06
AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13 va... 51 5e-06
AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13 va... 51 5e-06
AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13 pr... 51 5e-06
M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein. 51 7e-06
AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13 va... 51 7e-06
EF122242-1|ABO41977.1| 321|Homo sapiens cytochrome P450 2F1 var... 50 1e-05
BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family... 50 1e-05
BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family... 50 1e-05
AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxyl... 50 1e-05
J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrom... 47 8e-05
J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrom... 47 8e-05
DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family... 47 8e-05
DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1 pro... 47 8e-05
BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family... 47 8e-05
AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family... 47 8e-05
AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1 pro... 47 8e-05
EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1 var... 47 1e-04
BC109056-1|AAI09057.1| 320|Homo sapiens CYP2F1 protein protein. 47 1e-04
AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 pro... 47 1e-04
U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450 monooxyge... 46 2e-04
J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. 46 2e-04
BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family... 46 2e-04
BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family... 46 2e-04
AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family... 46 2e-04
AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein. 46 2e-04
AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2 pro... 46 2e-04
AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein. 45 4e-04
M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein. 44 6e-04
L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18 prot... 44 6e-04
BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein. 44 6e-04
BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein. 44 6e-04
BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family... 44 6e-04
BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family... 44 6e-04
BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family... 44 6e-04
AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family... 44 6e-04
AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family... 44 8e-04
AF144566-1|AAD30164.1| 339|Homo sapiens cytochrome P450 epoxyge... 44 8e-04
AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1 pro... 44 8e-04
BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family... 44 0.001
AY513607-1|AAR90938.1| 100|Homo sapiens truncated cytochrome P4... 44 0.001
AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein. 44 0.001
AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens ... 44 0.001
AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1 pro... 44 0.001
S63426-1|ABB76283.1| 214|Homo sapiens (S)-mephenytoin hydroxyla... 42 0.002
BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family... 42 0.002
Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein. 42 0.004
M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein. 42 0.004
M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein. 42 0.004
L16880-1|AAD13466.1| 273|Homo sapiens cytochrome P-450 2C protein. 42 0.004
D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein. 42 0.004
BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family... 42 0.004
BC070317-1|AAH70317.1| 162|Homo sapiens CYP2C9 protein protein. 42 0.004
BC020754-1|AAH20754.1| 162|Homo sapiens CYP2C9 protein protein. 42 0.004
AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family... 42 0.004
AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family... 42 0.004
AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family... 42 0.004
AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family... 42 0.004
AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family... 42 0.004
S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein. 41 0.005
M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrom... 41 0.005
M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrom... 41 0.005
AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family... 41 0.005
M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein. 41 0.007
AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family... 41 0.007
BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family... 40 0.009
AB209749-1|BAD92986.1| 210|Homo sapiens cytochrome P450, family... 39 0.021
M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein. 39 0.028
L39098-1|AAL31347.1| 160|Homo sapiens S-mephenytoin 4-hydroxyla... 39 0.028
AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family... 39 0.028
AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family... 39 0.028
AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family... 39 0.028
BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family... 38 0.050
BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family... 38 0.050
AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1 pro... 38 0.050
M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein. 38 0.066
AF280107-1|AAG32291.1| 106|Homo sapiens cytochrome P450 polypep... 35 0.46
BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein. 34 0.61
AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein. 33 1.1
DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6 pro... 32 3.3
AM086564-1|CAJ31103.1| 494|Homo sapiens steroid 21-hydroxylase,... 32 3.3
M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein. 31 4.3
M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein. 31 4.3
M12792-1|AAB59440.1| 494|Homo sapiens steroid 21-hydroxylase pr... 31 4.3
BX679671-8|CAM26070.1| 494|Homo sapiens cytochrome P450, family... 31 4.3
BC125182-1|AAI25183.1| 494|Homo sapiens cytochrome P450, family... 31 4.3
X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase ... 31 5.7
X58904-1|CAA41707.1| 371|Homo sapiens steroid 21-monooxygenase ... 31 5.7
X58902-1|CAA41706.1| 372|Homo sapiens steroid 21-monooxygenase ... 31 5.7
X58900-1|CAA41704.1| 372|Homo sapiens steroid 21-monooxygenase ... 31 5.7
X54807-1|CAA38578.1| 56|Homo sapiens unspecific monooxygenase ... 31 5.7
M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant 21... 31 5.7
M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human 21-hydrox... 31 5.7
BC125181-1|AAI25182.1| 495|Homo sapiens cytochrome P450, family... 31 5.7
AM183951-1|CAJ75805.1| 494|Homo sapiens steroid 21-hydroxylase,... 31 5.7
AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,... 31 5.7
AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,... 31 5.7
AM183948-1|CAJ75802.1| 494|Homo sapiens steroid 21-hydroxylase ... 31 5.7
AM183947-1|CAJ75801.1| 494|Homo sapiens steroid 21-hydroxylase,... 31 5.7
AM086565-1|CAJ31104.1| 494|Homo sapiens steroid 21-hydroxylase,... 31 5.7
AL929593-1|CAI41779.1| 495|Homo sapiens cytochrome P450, family... 31 5.7
AL662849-18|CAI17479.1| 495|Homo sapiens cytochrome P450, famil... 31 5.7
AL645922-24|CAI41754.1| 495|Homo sapiens cytochrome P450, famil... 31 5.7
AL049547-7|CAB89301.1| 495|Homo sapiens dJ34F7.3 (cytochrome P4... 31 5.7
AF280113-1|AAG33014.1| 74|Homo sapiens cytochrome P450 subfami... 31 5.7
AF280112-1|AAG33013.1| 126|Homo sapiens cytochrome P450 subfami... 31 5.7
AF019413-2|AAB67982.1| 495|Homo sapiens cytochrome P450 21-hydr... 31 5.7
BC004367-1|AAH04367.1| 313|Homo sapiens potassium channel, subf... 31 7.5
AK222545-1|BAD96265.1| 313|Homo sapiens potassium channel, subf... 31 7.5
AJ297404-1|CAC15489.1| 313|Homo sapiens potassium channel, subf... 31 7.5
AF281303-1|AAG10507.1| 179|Homo sapiens 2P domain K+ channel TW... 31 7.5
AF281302-1|AAG10506.1| 313|Homo sapiens 2P domain K+ channel TW... 31 7.5
AF134149-1|AAD22980.1| 313|Homo sapiens 2-pore K+ channel subun... 31 7.5
AF117708-1|AAD24000.1| 313|Homo sapiens tandem pore domain pota... 31 7.5
AM183946-1|CAJ75800.1| 494|Homo sapiens steroid 21-hydroxylase,... 30 10.0
AM183945-1|CAJ75799.1| 494|Homo sapiens steroid 21-hydroxylase,... 30 10.0
AK024290-1|BAB14875.1| 590|Homo sapiens protein ( Homo sapiens ... 30 10.0
AB040956-1|BAA96047.1| 687|Homo sapiens KIAA1523 protein protein. 30 10.0
>BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family 4,
subfamily V, polypeptide 2 protein.
Length = 525
Score = 130 bits (314), Expect = 7e-30
Identities = 69/188 (36%), Positives = 112/188 (59%), Gaps = 6/188 (3%)
Frame = +1
Query: 238 SHMHKLAELLPGPA---PIPIFGNALTLMRKSPHELVNLALGYAQTFGNV--VRVWLGSK 402
S+ K ++ P P P+ G+AL LM+ E + Y + + ++ +++W+G
Sbjct: 39 SYARKWQQMRPIPTVARAYPLVGHAL-LMKPDGREFFQQIIEYTEEYRHMPLLKLWVGPV 97
Query: 403 LIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPTFHIN 582
+V L +A+++E+IL S IDK++ YKF +PWLG GLL S+G KWRS RKM+ PTFH
Sbjct: 98 PMVALYNAENVEVILTSSKQIDKSSMYKFLEPWLGLGLLTSTGNKWRSRRKMLTPTFHFT 157
Query: 583 ILKSFVGIFNQNSNNVVEKLKSEVG-KTFDVHDYMSGTTVDILLETAMGISRKTQDESXF 759
IL+ F+ I N+ +N +V+KL+ + + F+ Y++ +DI+ ETAMG + Q
Sbjct: 158 ILEDFLDIMNEQANILVKKLEKHINQEAFNCFFYITLCALDIICETAMGKNIGAQSNDDS 217
Query: 760 DYAMAVMK 783
+Y AV +
Sbjct: 218 EYVRAVYR 225
>AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2
protein.
Length = 525
Score = 130 bits (314), Expect = 7e-30
Identities = 69/188 (36%), Positives = 112/188 (59%), Gaps = 6/188 (3%)
Frame = +1
Query: 238 SHMHKLAELLPGPA---PIPIFGNALTLMRKSPHELVNLALGYAQTFGNV--VRVWLGSK 402
S+ K ++ P P P+ G+AL LM+ E + Y + + ++ +++W+G
Sbjct: 39 SYARKWQQMRPIPTVARAYPLVGHAL-LMKPDGREFFQQIIEYTEEYRHMPLLKLWVGPV 97
Query: 403 LIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPTFHIN 582
+V L +A+++E+IL S IDK++ YKF +PWLG GLL S+G KWRS RKM+ PTFH
Sbjct: 98 PMVALYNAENVEVILTSSKQIDKSSMYKFLEPWLGLGLLTSTGNKWRSRRKMLTPTFHFT 157
Query: 583 ILKSFVGIFNQNSNNVVEKLKSEVG-KTFDVHDYMSGTTVDILLETAMGISRKTQDESXF 759
IL+ F+ I N+ +N +V+KL+ + + F+ Y++ +DI+ ETAMG + Q
Sbjct: 158 ILEDFLDIMNEQANILVKKLEKHINQEAFNCFFYITLCALDIICETAMGKNIGAQSNDDS 217
Query: 760 DYAMAVMK 783
+Y AV +
Sbjct: 218 EYVRAVYR 225
>AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens
cDNA FLJ16007 fis, clone KIDNE2006580, weakly similar
to CYTOCHROME P450 4C1 (EC 1.14.14.1). ).
Length = 525
Score = 130 bits (314), Expect = 7e-30
Identities = 69/188 (36%), Positives = 112/188 (59%), Gaps = 6/188 (3%)
Frame = +1
Query: 238 SHMHKLAELLPGPA---PIPIFGNALTLMRKSPHELVNLALGYAQTFGNV--VRVWLGSK 402
S+ K ++ P P P+ G+AL LM+ E + Y + + ++ +++W+G
Sbjct: 39 SYARKWQQMRPIPTVARAYPLVGHAL-LMKPDGREFFQQIIEYTEEYRHMPLLKLWVGPV 97
Query: 403 LIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPTFHIN 582
+V L +A+++E+IL S IDK++ YKF +PWLG GLL S+G KWRS RKM+ PTFH
Sbjct: 98 PMVALYNAENVEVILTSSKQIDKSSMYKFLEPWLGLGLLTSTGNKWRSRRKMLTPTFHFT 157
Query: 583 ILKSFVGIFNQNSNNVVEKLKSEVG-KTFDVHDYMSGTTVDILLETAMGISRKTQDESXF 759
IL+ F+ I N+ +N +V+KL+ + + F+ Y++ +DI+ ETAMG + Q
Sbjct: 158 ILEDFLDIMNEQANILVKKLEKHINQEAFNCFFYITLCALDIICETAMGKNIGAQSNDDS 217
Query: 760 DYAMAVMK 783
+Y AV +
Sbjct: 218 EYVRAVYR 225
>AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens
cDNA FLJ44509 fis, clone UTERU3001585, weakly similar
to Cytochrome P450 4c3 (EC 1.14.-.-). ).
Length = 503
Score = 124 bits (300), Expect = 3e-28
Identities = 61/161 (37%), Positives = 99/161 (61%), Gaps = 3/161 (1%)
Frame = +1
Query: 310 LMRKSPHELVNLALGYAQTFGNV--VRVWLGSKLIVFLADADDIEIILNSHVHIDKATEY 483
LM+ E + Y + + ++ +++W+G +V L +A+++E+IL S IDK++ Y
Sbjct: 43 LMKPDGREFFQQIIEYTEEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMY 102
Query: 484 KFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVG-K 660
KF +PWLG GLL S+G KWRS RKM+ PTFH IL+ F+ I N+ +N +V+KL+ + +
Sbjct: 103 KFLEPWLGLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQE 162
Query: 661 TFDVHDYMSGTTVDILLETAMGISRKTQDESXFDYAMAVMK 783
F+ Y++ +DI+ ETAMG + Q +Y AV +
Sbjct: 163 AFNCFFYITLCALDIICETAMGKNIGAQSNDDSEYVRAVYR 203
>BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 12 protein.
Length = 524
Score = 94.3 bits (224), Expect = 5e-19
Identities = 65/221 (29%), Positives = 106/221 (47%), Gaps = 10/221 (4%)
Frame = +1
Query: 187 LLGLTTAIWILYR---WQQNSHMH-KLAELLPGPAPIPIFGNALTLMRKSPHELVNLALG 354
LL L W+L R W + + + + P P F L L+ + L + +
Sbjct: 21 LLLLVVGSWLLARILAWTYAFYNNCRRLQCFPQPPKRNWFWGHLGLITPTEEGLKD-STQ 79
Query: 355 YAQTFGNVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLLIS 525
+ T+ VWLG + + L D I I N+ I +F KPWLGEG+L+S
Sbjct: 80 MSATYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLS 139
Query: 526 SGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEK---LKSEVGKTFDVHDYMSGTT 696
G KW HR+M+ P FH NILKS++ IFN+++N +++K L SE D+ +++S T
Sbjct: 140 GGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSCLDMFEHISLMT 199
Query: 697 VDILLETAMGISRKTQDESXFDYAMAVMKCAISSTKXTTNL 819
+D L + Q E +Y +++ + K + ++
Sbjct: 200 LDSLQKCIFSFDSHCQ-ERPSEYIATILELSALVEKRSQHI 239
>AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein.
Length = 524
Score = 94.3 bits (224), Expect = 5e-19
Identities = 65/221 (29%), Positives = 106/221 (47%), Gaps = 10/221 (4%)
Frame = +1
Query: 187 LLGLTTAIWILYR---WQQNSHMH-KLAELLPGPAPIPIFGNALTLMRKSPHELVNLALG 354
LL L W+L R W + + + + P P F L L+ + L + +
Sbjct: 21 LLLLVVGSWLLARILAWTYAFYNNCRRLQCFPQPPKRNWFWGHLGLITPTEEGLKD-STQ 79
Query: 355 YAQTFGNVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLLIS 525
+ T+ VWLG + + L D I I N+ I +F KPWLGEG+L+S
Sbjct: 80 MSATYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLS 139
Query: 526 SGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEK---LKSEVGKTFDVHDYMSGTT 696
G KW HR+M+ P FH NILKS++ IFN+++N +++K L SE D+ +++S T
Sbjct: 140 GGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMT 199
Query: 697 VDILLETAMGISRKTQDESXFDYAMAVMKCAISSTKXTTNL 819
+D L + Q E +Y +++ + K + ++
Sbjct: 200 LDSLQKCIFSFDSHCQ-ERPSEYIATILELSALVEKRSQHI 239
>AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform
4F12 protein.
Length = 524
Score = 94.3 bits (224), Expect = 5e-19
Identities = 65/221 (29%), Positives = 106/221 (47%), Gaps = 10/221 (4%)
Frame = +1
Query: 187 LLGLTTAIWILYR---WQQNSHMH-KLAELLPGPAPIPIFGNALTLMRKSPHELVNLALG 354
LL L W+L R W + + + + P P F L L+ + L + +
Sbjct: 21 LLLLVVGSWLLARILAWTYAFYNNCRRLQCFPQPPKRNWFWGHLGLITPTEEGLKD-STQ 79
Query: 355 YAQTFGNVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLLIS 525
+ T+ VWLG + + L D I I N+ I +F KPWLGEG+L+S
Sbjct: 80 MSATYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLS 139
Query: 526 SGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEK---LKSEVGKTFDVHDYMSGTT 696
G KW HR+M+ P FH NILKS++ IFN+++N +++K L SE D+ +++S T
Sbjct: 140 GGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMT 199
Query: 697 VDILLETAMGISRKTQDESXFDYAMAVMKCAISSTKXTTNL 819
+D L + Q E +Y +++ + K + ++
Sbjct: 200 LDSLQKCIFSFDSHCQ-ERPSEYIATILELSALVEKRSQHI 239
>AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 94.3 bits (224), Expect = 5e-19
Identities = 65/221 (29%), Positives = 106/221 (47%), Gaps = 10/221 (4%)
Frame = +1
Query: 187 LLGLTTAIWILYR---WQQNSHMH-KLAELLPGPAPIPIFGNALTLMRKSPHELVNLALG 354
LL L W+L R W + + + + P P F L L+ + L + +
Sbjct: 21 LLLLVVGSWLLARILAWTYAFYNNCRRLQCFPQPPKRNWFWGHLGLITPTEEGLKD-STQ 79
Query: 355 YAQTFGNVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLLIS 525
+ T+ VWLG + + L D I I N+ I +F KPWLGEG+L+S
Sbjct: 80 MSATYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLS 139
Query: 526 SGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEK---LKSEVGKTFDVHDYMSGTT 696
G KW HR+M+ P FH NILKS++ IFN+++N +++K L SE D+ +++S T
Sbjct: 140 GGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMT 199
Query: 697 VDILLETAMGISRKTQDESXFDYAMAVMKCAISSTKXTTNL 819
+D L + Q E +Y +++ + K + ++
Sbjct: 200 LDSLQKCIFSFDSHCQ-ERPSEYIATILELSALVEKRSQHI 239
>AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 94.3 bits (224), Expect = 5e-19
Identities = 65/221 (29%), Positives = 106/221 (47%), Gaps = 10/221 (4%)
Frame = +1
Query: 187 LLGLTTAIWILYR---WQQNSHMH-KLAELLPGPAPIPIFGNALTLMRKSPHELVNLALG 354
LL L W+L R W + + + + P P F L L+ + L + +
Sbjct: 21 LLLLVVGSWLLARILAWTYAFYNNCRRLQCFPQPPKRNWFWGHLGLITPTEEGLKD-STQ 79
Query: 355 YAQTFGNVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLLIS 525
+ T+ VWLG + + L D I I N+ I +F KPWLGEG+L+S
Sbjct: 80 MSATYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLS 139
Query: 526 SGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEK---LKSEVGKTFDVHDYMSGTT 696
G KW HR+M+ P FH NILKS++ IFN+++N +++K L SE D+ +++S T
Sbjct: 140 GGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMT 199
Query: 697 VDILLETAMGISRKTQDESXFDYAMAVMKCAISSTKXTTNL 819
+D L + Q E +Y +++ + K + ++
Sbjct: 200 LDSLQKCIFSFDSHCQ-ERPSEYIATILELSALVEKRSQHI 239
>AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein.
Length = 458
Score = 93.1 bits (221), Expect = 1e-18
Identities = 51/158 (32%), Positives = 83/158 (52%), Gaps = 6/158 (3%)
Frame = +1
Query: 364 TFGNVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLLISSGP 534
T+ +WLG + + L D I I N+ I +F KPWLGEG+L+S G
Sbjct: 17 TYSQGFTIWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGGD 76
Query: 535 KWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEK---LKSEVGKTFDVHDYMSGTTVDI 705
KW HR+M+ P FH NILKS++ IFN+++N +++K L SE D+ +++S T+D
Sbjct: 77 KWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSCLDMFEHISLMTLDS 136
Query: 706 LLETAMGISRKTQDESXFDYAMAVMKCAISSTKXTTNL 819
L + Q E +Y +++ + K + ++
Sbjct: 137 LQKCIFSFDSHCQ-ERPSEYIATILELSALVEKRSQHI 173
>U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein.
Length = 520
Score = 89.8 bits (213), Expect = 1e-17
Identities = 58/187 (31%), Positives = 94/187 (50%), Gaps = 6/187 (3%)
Frame = +1
Query: 334 LVNLALGYAQTFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHIDKATE--YKFFKPWL 504
L L Y Q F +VW+G ++ L D I ++N+ I + Y F +PWL
Sbjct: 77 LTQLVATYPQGF----KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWL 132
Query: 505 GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEK---LKSEVGKTFDVH 675
G+GLL+S+G KW HR+M+ P FH NILK ++ IFN++ N + K L SE D+
Sbjct: 133 GDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMF 192
Query: 676 DYMSGTTVDILLETAMGISRKTQDESXFDYAMAVMKCAISSTKXTTNLGCEPRMFQVDFV 855
+++S T+D L + Q E +Y A+++ + +K + + +DF+
Sbjct: 193 EHISLMTLDSLQKCVFSFDSHCQ-EKPSEYIAAILELSALVSKRHHEI-----LLHIDFL 246
Query: 856 FNTTNFG 876
+ T G
Sbjct: 247 YYLTPDG 253
>D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 89.8 bits (213), Expect = 1e-17
Identities = 58/187 (31%), Positives = 94/187 (50%), Gaps = 6/187 (3%)
Frame = +1
Query: 334 LVNLALGYAQTFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHIDKATE--YKFFKPWL 504
L L Y Q F +VW+G ++ L D I ++N+ I + Y F +PWL
Sbjct: 77 LTQLVATYPQGF----KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWL 132
Query: 505 GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEK---LKSEVGKTFDVH 675
G+GLL+S+G KW HR+M+ P FH NILK ++ IFN++ N + K L SE D+
Sbjct: 133 GDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMF 192
Query: 676 DYMSGTTVDILLETAMGISRKTQDESXFDYAMAVMKCAISSTKXTTNLGCEPRMFQVDFV 855
+++S T+D L + Q E +Y A+++ + +K + + +DF+
Sbjct: 193 EHISLMTLDSLQKCVFSFDSHCQ-EKPSEYIAAILELSALVSKRHHEI-----LLHIDFL 246
Query: 856 FNTTNFG 876
+ T G
Sbjct: 247 YYLTPDG 253
>D12621-1|BAA02145.1| 389|Homo sapiens cytochrome P-450LTBV
protein.
Length = 389
Score = 89.8 bits (213), Expect = 1e-17
Identities = 75/241 (31%), Positives = 113/241 (46%), Gaps = 11/241 (4%)
Frame = +1
Query: 187 LLGLTTAIWILYR---WQQNSHMHKLA-ELLPGPAPIPIFGNALTLMRKSPHELVNLALG 354
LL L A W+L R W + + P P F L L+ S L+
Sbjct: 21 LLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWFLGHLGLIHSSEEGLL-YTQS 79
Query: 355 YAQTFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHI---DKATEYKFFKPWLGEGLLI 522
A TFG++ W+G IV + I+ +L + I DK Y F KPWLG+GLL+
Sbjct: 80 LACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVF-YSFLKPWLGDGLLL 138
Query: 523 SSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEK---LKSEVGKTFDVHDYMSGT 693
S+G KW HR+M+ P FH NILK ++ IFN++ N + K L SE D+ +++S
Sbjct: 139 SAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLM 198
Query: 694 TVDILLETAMGISRKTQDESXFDYAMAVMKCAISSTKXTTNLGCEPRMFQVDFVFNTTNF 873
T+D L + Q E +Y A+++ + TK + + +DF++ T
Sbjct: 199 TLDSLQKCVFSFDSHCQ-EKPSEYIAAILELSALVTKRHQQI-----LLYIDFLYYLTPD 252
Query: 874 G 876
G
Sbjct: 253 G 253
>D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV
protein.
Length = 520
Score = 89.8 bits (213), Expect = 1e-17
Identities = 75/241 (31%), Positives = 113/241 (46%), Gaps = 11/241 (4%)
Frame = +1
Query: 187 LLGLTTAIWILYR---WQQNSHMHKLA-ELLPGPAPIPIFGNALTLMRKSPHELVNLALG 354
LL L A W+L R W + + P P F L L+ S L+
Sbjct: 21 LLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWFLGHLGLIHSSEEGLL-YTQS 79
Query: 355 YAQTFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHI---DKATEYKFFKPWLGEGLLI 522
A TFG++ W+G IV + I+ +L + I DK Y F KPWLG+GLL+
Sbjct: 80 LACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVF-YSFLKPWLGDGLLL 138
Query: 523 SSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEK---LKSEVGKTFDVHDYMSGT 693
S+G KW HR+M+ P FH NILK ++ IFN++ N + K L SE D+ +++S
Sbjct: 139 SAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLM 198
Query: 694 TVDILLETAMGISRKTQDESXFDYAMAVMKCAISSTKXTTNLGCEPRMFQVDFVFNTTNF 873
T+D L + Q E +Y A+++ + TK + + +DF++ T
Sbjct: 199 TLDSLQKCVFSFDSHCQ-EKPSEYIAAILELSALVTKRHQQI-----LLYIDFLYYLTPD 252
Query: 874 G 876
G
Sbjct: 253 G 253
>BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 89.8 bits (213), Expect = 1e-17
Identities = 58/187 (31%), Positives = 94/187 (50%), Gaps = 6/187 (3%)
Frame = +1
Query: 334 LVNLALGYAQTFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHIDKATE--YKFFKPWL 504
L L Y Q F +VW+G ++ L D I ++N+ I + Y F +PWL
Sbjct: 77 LTQLVATYPQGF----KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWL 132
Query: 505 GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEK---LKSEVGKTFDVH 675
G+GLL+S+G KW HR+M+ P FH NILK ++ IFN++ N + K L SE D+
Sbjct: 133 GDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMF 192
Query: 676 DYMSGTTVDILLETAMGISRKTQDESXFDYAMAVMKCAISSTKXTTNLGCEPRMFQVDFV 855
+++S T+D L + Q E +Y A+++ + +K + + +DF+
Sbjct: 193 EHISLMTLDSLQKCVFSFDSHCQ-EKPSEYIAAILELSALVSKRHHEI-----LLHIDFL 246
Query: 856 FNTTNFG 876
+ T G
Sbjct: 247 YYLTPDG 253
>BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 89.8 bits (213), Expect = 1e-17
Identities = 58/187 (31%), Positives = 94/187 (50%), Gaps = 6/187 (3%)
Frame = +1
Query: 334 LVNLALGYAQTFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHIDKATE--YKFFKPWL 504
L L Y Q F +VW+G ++ L D I ++N+ I + Y F +PWL
Sbjct: 77 LTQLVATYPQGF----KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWL 132
Query: 505 GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEK---LKSEVGKTFDVH 675
G+GLL+S+G KW HR+M+ P FH NILK ++ IFN++ N + K L SE D+
Sbjct: 133 GDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMF 192
Query: 676 DYMSGTTVDILLETAMGISRKTQDESXFDYAMAVMKCAISSTKXTTNLGCEPRMFQVDFV 855
+++S T+D L + Q E +Y A+++ + +K + + +DF+
Sbjct: 193 EHISLMTLDSLQKCVFSFDSHCQ-EKPSEYIAAILELSALVSKRHHEI-----LLHIDFL 246
Query: 856 FNTTNFG 876
+ T G
Sbjct: 247 YYLTPDG 253
>AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 3 protein.
Length = 520
Score = 89.8 bits (213), Expect = 1e-17
Identities = 75/241 (31%), Positives = 113/241 (46%), Gaps = 11/241 (4%)
Frame = +1
Query: 187 LLGLTTAIWILYR---WQQNSHMHKLA-ELLPGPAPIPIFGNALTLMRKSPHELVNLALG 354
LL L A W+L R W + + P P F L L+ S L+
Sbjct: 21 LLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWFLGHLGLIHSSEEGLL-YTQS 79
Query: 355 YAQTFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHI---DKATEYKFFKPWLGEGLLI 522
A TFG++ W+G IV + I+ +L + I DK Y F KPWLG+GLL+
Sbjct: 80 LACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVF-YSFLKPWLGDGLLL 138
Query: 523 SSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEK---LKSEVGKTFDVHDYMSGT 693
S+G KW HR+M+ P FH NILK ++ IFN++ N + K L SE D+ +++S
Sbjct: 139 SAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLM 198
Query: 694 TVDILLETAMGISRKTQDESXFDYAMAVMKCAISSTKXTTNLGCEPRMFQVDFVFNTTNF 873
T+D L + Q E +Y A+++ + TK + + +DF++ T
Sbjct: 199 TLDSLQKCVFSFDSHCQ-EKPSEYIAAILELSALVTKRHQQI-----LLYIDFLYYLTPD 252
Query: 874 G 876
G
Sbjct: 253 G 253
>AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfamily
IVF, polypeptide 2 protein.
Length = 520
Score = 89.8 bits (213), Expect = 1e-17
Identities = 58/187 (31%), Positives = 94/187 (50%), Gaps = 6/187 (3%)
Frame = +1
Query: 334 LVNLALGYAQTFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHIDKATE--YKFFKPWL 504
L L Y Q F +VW+G ++ L D I ++N+ I + Y F +PWL
Sbjct: 77 LTQLVATYPQGF----KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWL 132
Query: 505 GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEK---LKSEVGKTFDVH 675
G+GLL+S+G KW HR+M+ P FH NILK ++ IFN++ N + K L SE D+
Sbjct: 133 GDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMF 192
Query: 676 DYMSGTTVDILLETAMGISRKTQDESXFDYAMAVMKCAISSTKXTTNLGCEPRMFQVDFV 855
+++S T+D L + Q E +Y A+++ + +K + + +DF+
Sbjct: 193 EHISLMTLDSLQKCVFSFDSHCQ-EKPSEYIAAILELSALVSKRHHEI-----LLHIDFL 246
Query: 856 FNTTNFG 876
+ T G
Sbjct: 247 YYLTPDG 253
>AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein.
Length = 520
Score = 89.8 bits (213), Expect = 1e-17
Identities = 58/187 (31%), Positives = 94/187 (50%), Gaps = 6/187 (3%)
Frame = +1
Query: 334 LVNLALGYAQTFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHIDKATE--YKFFKPWL 504
L L Y Q F +VW+G ++ L D I ++N+ I + Y F +PWL
Sbjct: 77 LTQLVATYPQGF----KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWL 132
Query: 505 GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEK---LKSEVGKTFDVH 675
G+GLL+S+G KW HR+M+ P FH NILK ++ IFN++ N + K L SE D+
Sbjct: 133 GDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMF 192
Query: 676 DYMSGTTVDILLETAMGISRKTQDESXFDYAMAVMKCAISSTKXTTNLGCEPRMFQVDFV 855
+++S T+D L + Q E +Y A+++ + +K + + +DF+
Sbjct: 193 EHISLMTLDSLQKCVFSFDSHCQ-EKPSEYIAAILELSALVSKRHHEI-----LLHIDFL 246
Query: 856 FNTTNFG 876
+ T G
Sbjct: 247 YYLTPDG 253
>AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 89.8 bits (213), Expect = 1e-17
Identities = 58/187 (31%), Positives = 94/187 (50%), Gaps = 6/187 (3%)
Frame = +1
Query: 334 LVNLALGYAQTFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHIDKATE--YKFFKPWL 504
L L Y Q F +VW+G ++ L D I ++N+ I + Y F +PWL
Sbjct: 77 LTQLVATYPQGF----KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWL 132
Query: 505 GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEK---LKSEVGKTFDVH 675
G+GLL+S+G KW HR+M+ P FH NILK ++ IFN++ N + K L SE D+
Sbjct: 133 GDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMF 192
Query: 676 DYMSGTTVDILLETAMGISRKTQDESXFDYAMAVMKCAISSTKXTTNLGCEPRMFQVDFV 855
+++S T+D L + Q E +Y A+++ + +K + + +DF+
Sbjct: 193 EHISLMTLDSLQKCVFSFDSHCQ-EKPSEYIAAILELSALVSKRHHEI-----LLHIDFL 246
Query: 856 FNTTNFG 876
+ T G
Sbjct: 247 YYLTPDG 253
>AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 89.8 bits (213), Expect = 1e-17
Identities = 75/241 (31%), Positives = 113/241 (46%), Gaps = 11/241 (4%)
Frame = +1
Query: 187 LLGLTTAIWILYR---WQQNSHMHKLA-ELLPGPAPIPIFGNALTLMRKSPHELVNLALG 354
LL L A W+L R W + + P P F L L+ S L+
Sbjct: 21 LLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWFLGHLGLIHSSEEGLL-YTQS 79
Query: 355 YAQTFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHI---DKATEYKFFKPWLGEGLLI 522
A TFG++ W+G IV + I+ +L + I DK Y F KPWLG+GLL+
Sbjct: 80 LACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVF-YSFLKPWLGDGLLL 138
Query: 523 SSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEK---LKSEVGKTFDVHDYMSGT 693
S+G KW HR+M+ P FH NILK ++ IFN++ N + K L SE D+ +++S
Sbjct: 139 SAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLM 198
Query: 694 TVDILLETAMGISRKTQDESXFDYAMAVMKCAISSTKXTTNLGCEPRMFQVDFVFNTTNF 873
T+D L + Q E +Y A+++ + TK + + +DF++ T
Sbjct: 199 TLDSLQKCVFSFDSHCQ-EKPSEYIAAILELSALVTKRHQQI-----LLYIDFLYYLTPD 252
Query: 874 G 876
G
Sbjct: 253 G 253
>AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 89.8 bits (213), Expect = 1e-17
Identities = 75/241 (31%), Positives = 113/241 (46%), Gaps = 11/241 (4%)
Frame = +1
Query: 187 LLGLTTAIWILYR---WQQNSHMHKLA-ELLPGPAPIPIFGNALTLMRKSPHELVNLALG 354
LL L A W+L R W + + P P F L L+ S L+
Sbjct: 21 LLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWFLGHLGLIHSSEEGLL-YTQS 79
Query: 355 YAQTFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHI---DKATEYKFFKPWLGEGLLI 522
A TFG++ W+G IV + I+ +L + I DK Y F KPWLG+GLL+
Sbjct: 80 LACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVF-YSFLKPWLGDGLLL 138
Query: 523 SSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEK---LKSEVGKTFDVHDYMSGT 693
S+G KW HR+M+ P FH NILK ++ IFN++ N + K L SE D+ +++S
Sbjct: 139 SAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLM 198
Query: 694 TVDILLETAMGISRKTQDESXFDYAMAVMKCAISSTKXTTNLGCEPRMFQVDFVFNTTNF 873
T+D L + Q E +Y A+++ + TK + + +DF++ T
Sbjct: 199 TLDSLQKCVFSFDSHCQ-EKPSEYIAAILELSALVTKRHQQI-----LLYIDFLYYLTPD 252
Query: 874 G 876
G
Sbjct: 253 G 253
>BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 89.0 bits (211), Expect = 2e-17
Identities = 58/187 (31%), Positives = 93/187 (49%), Gaps = 6/187 (3%)
Frame = +1
Query: 334 LVNLALGYAQTFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHIDKATE--YKFFKPWL 504
L L Y Q F +VW+G ++ L D I ++N+ I + Y F +PWL
Sbjct: 77 LTQLVATYPQGF----KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWL 132
Query: 505 GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEK---LKSEVGKTFDVH 675
G+GLL+S+G KW HR+M+ P FH NILK ++ IFN + N + K L SE D+
Sbjct: 133 GDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNDSVNIMHAKWQLLASEGSACLDMF 192
Query: 676 DYMSGTTVDILLETAMGISRKTQDESXFDYAMAVMKCAISSTKXTTNLGCEPRMFQVDFV 855
+++S T+D L + Q E +Y A+++ + +K + + +DF+
Sbjct: 193 EHISLMTLDSLQKCVFSFDSHCQ-EKPSEYIAAILELSALVSKRHHEI-----LLHIDFL 246
Query: 856 FNTTNFG 876
+ T G
Sbjct: 247 YYLTPDG 253
>AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein.
Length = 520
Score = 87.4 bits (207), Expect = 6e-17
Identities = 57/156 (36%), Positives = 84/156 (53%), Gaps = 6/156 (3%)
Frame = +1
Query: 334 LVNLALGYAQTFGNVVRVWLGSKL-IVFLADADDIEIILNSHVHI-DK-ATEYKFFKPWL 504
L L Y Q F VR WLG I+ L D + ++N+ I DK YK KPWL
Sbjct: 77 LTQLVATYPQGF---VR-WLGPITPIINLCHPDIVRSVINTSDAITDKDIVFYKTLKPWL 132
Query: 505 GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNV---VEKLKSEVGKTFDVH 675
G+GLL+S G KWR HR+++ P FH NILK ++ IF++++N + ++L E DV
Sbjct: 133 GDGLLLSVGDKWRHHRRLLTPAFHFNILKPYIKIFSKSANIMHAKWQRLAMEGSTCLDVF 192
Query: 676 DYMSGTTVDILLETAMGISRKTQDESXFDYAMAVMK 783
+++S T+D L + Q E +Y A+M+
Sbjct: 193 EHISLMTLDSLQKCIFSFDSNCQ-EKPSEYITAIME 227
>AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein.
Length = 520
Score = 87.4 bits (207), Expect = 6e-17
Identities = 59/188 (31%), Positives = 94/188 (50%), Gaps = 7/188 (3%)
Frame = +1
Query: 334 LVNLALGYAQTFGNVVRVWLGSKL-IVFLADADDIEIILNSHVHI---DKATEYKFFKPW 501
L L Y Q F +VW+G ++ + I ++N+ I DK Y F KPW
Sbjct: 77 LTQLVATYPQGF----KVWMGPIFPVIRFCHPNIIRSVINASAAIVPKDKVF-YSFLKPW 131
Query: 502 LGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEK---LKSEVGKTFDV 672
LG+GLL+S+G KW HR+M+ P FH NILK ++ IFN++ N + K L S+ D+
Sbjct: 132 LGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASKGYARLDM 191
Query: 673 HDYMSGTTVDILLETAMGISRKTQDESXFDYAMAVMKCAISSTKXTTNLGCEPRMFQVDF 852
+++S T+D L + Q E +Y A+++ + TK + + +DF
Sbjct: 192 FEHISLMTLDSLQKCVFSFDSHCQ-EKPSEYIAAILELSALVTKRHQQI-----LLYIDF 245
Query: 853 VFNTTNFG 876
++ T G
Sbjct: 246 LYYLTPDG 253
>BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein.
Length = 524
Score = 87.0 bits (206), Expect = 8e-17
Identities = 58/187 (31%), Positives = 90/187 (48%), Gaps = 6/187 (3%)
Frame = +1
Query: 334 LVNLALGYAQTFGNVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATE--YKFFKPWL 504
L L Y Q F ++WLG ++ L D I I ++ + Y F KPWL
Sbjct: 77 LTQLVTTYPQGF----KLWLGPTFPLLILCHPDIIRPITSASAAVAPKDMIFYGFLKPWL 132
Query: 505 GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEK---LKSEVGKTFDVH 675
G+GLL+S G KW HR+M+ P FH NILK ++ IFN++ N + +K L SE D+
Sbjct: 133 GDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLDMF 192
Query: 676 DYMSGTTVDILLETAMGISRKTQDESXFDYAMAVMKCAISSTKXTTNLGCEPRMFQVDFV 855
+++S T+D L + Q E +Y A+++ + K + + DF+
Sbjct: 193 EHISLMTLDSLQKCVFSFESNCQ-EKPSEYIAAILELSAFVEKRNQQI-----LLHTDFL 246
Query: 856 FNTTNFG 876
+ T G
Sbjct: 247 YYLTPDG 253
>AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein.
Length = 524
Score = 87.0 bits (206), Expect = 8e-17
Identities = 58/187 (31%), Positives = 90/187 (48%), Gaps = 6/187 (3%)
Frame = +1
Query: 334 LVNLALGYAQTFGNVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATE--YKFFKPWL 504
L L Y Q F ++WLG ++ L D I I ++ + Y F KPWL
Sbjct: 77 LTQLVTTYPQGF----KLWLGPTFPLLILCHPDIIRPITSASAAVAPKDMIFYGFLKPWL 132
Query: 505 GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEK---LKSEVGKTFDVH 675
G+GLL+S G KW HR+M+ P FH NILK ++ IFN++ N + +K L SE D+
Sbjct: 133 GDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLDMF 192
Query: 676 DYMSGTTVDILLETAMGISRKTQDESXFDYAMAVMKCAISSTKXTTNLGCEPRMFQVDFV 855
+++S T+D L + Q E +Y A+++ + K + + DF+
Sbjct: 193 EHISLMTLDSLQKCVFSFESNCQ-EKPSEYIAAILELSAFVEKRNQQI-----LLHTDFL 246
Query: 856 FNTTNFG 876
+ T G
Sbjct: 247 YYLTPDG 253
>BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 85.8 bits (203), Expect = 2e-16
Identities = 49/150 (32%), Positives = 83/150 (55%), Gaps = 6/150 (4%)
Frame = +1
Query: 373 NVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATE--YKFFKPWLGEGLLISSGPKWR 543
+V+ VW+G L ++ L D I+ +L + I + Y F KPWLG+GLL+S G KW
Sbjct: 94 HVLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGLLLSKGDKWS 153
Query: 544 SHRKMIAPTFHINILKSFVGIFNQNSNNVVEK---LKSEVGKTFDVHDYMSGTTVDILLE 714
HR+++ P FH +ILK ++ IFNQ+++ + K L + D+ +++S T+D L +
Sbjct: 154 RHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHISLMTLDSLQK 213
Query: 715 TAMGISRKTQDESXFDYAMAVMKCAISSTK 804
+ Q E DY A+++ + S +
Sbjct: 214 CVFSYNSNCQ-EKMSDYISAIIELSALSVR 242
>BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 85.8 bits (203), Expect = 2e-16
Identities = 49/150 (32%), Positives = 83/150 (55%), Gaps = 6/150 (4%)
Frame = +1
Query: 373 NVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATE--YKFFKPWLGEGLLISSGPKWR 543
+V+ VW+G L ++ L D I+ +L + I + Y F KPWLG+GLL+S G KW
Sbjct: 94 HVLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGLLLSKGDKWS 153
Query: 544 SHRKMIAPTFHINILKSFVGIFNQNSNNVVEK---LKSEVGKTFDVHDYMSGTTVDILLE 714
HR+++ P FH +ILK ++ IFNQ+++ + K L + D+ +++S T+D L +
Sbjct: 154 RHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHISLMTLDSLQK 213
Query: 715 TAMGISRKTQDESXFDYAMAVMKCAISSTK 804
+ Q E DY A+++ + S +
Sbjct: 214 CVFSYNSNCQ-EKMSDYISAIIELSALSVR 242
>BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 85.8 bits (203), Expect = 2e-16
Identities = 49/150 (32%), Positives = 83/150 (55%), Gaps = 6/150 (4%)
Frame = +1
Query: 373 NVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATE--YKFFKPWLGEGLLISSGPKWR 543
+V+ VW+G L ++ L D I+ +L + I + Y F KPWLG+GLL+S G KW
Sbjct: 94 HVLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGLLLSKGDKWS 153
Query: 544 SHRKMIAPTFHINILKSFVGIFNQNSNNVVEK---LKSEVGKTFDVHDYMSGTTVDILLE 714
HR+++ P FH +ILK ++ IFNQ+++ + K L + D+ +++S T+D L +
Sbjct: 154 RHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHISLMTLDSLQK 213
Query: 715 TAMGISRKTQDESXFDYAMAVMKCAISSTK 804
+ Q E DY A+++ + S +
Sbjct: 214 CVFSYNSNCQ-EKMSDYISAIIELSALSVR 242
>X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for
cytochrome P-450HP. ).
Length = 511
Score = 83.8 bits (198), Expect = 8e-16
Identities = 51/182 (28%), Positives = 86/182 (47%), Gaps = 2/182 (1%)
Frame = +1
Query: 187 LLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQT 366
+LG I +L R Q + K + PGP +FG+AL + + V + +A
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 367 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 546
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 547 HRKMIAPTFHINILKSFVGIFNQNSNNVVEKL--KSEVGKTFDVHDYMSGTTVDILLETA 720
HRK++ P FH ++LK +V +F +++ +++K K+ GK+FD+ + ++ L++
Sbjct: 137 HRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCT 196
Query: 721 MG 726
G
Sbjct: 197 FG 198
>DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 83.8 bits (198), Expect = 8e-16
Identities = 51/182 (28%), Positives = 86/182 (47%), Gaps = 2/182 (1%)
Frame = +1
Query: 187 LLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQT 366
+LG I +L R Q + K + PGP +FG+AL + + V + +A
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 367 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 546
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 547 HRKMIAPTFHINILKSFVGIFNQNSNNVVEKL--KSEVGKTFDVHDYMSGTTVDILLETA 720
HRK++ P FH ++LK +V +F +++ +++K K+ GK+FD+ + ++ L++
Sbjct: 137 HRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCT 196
Query: 721 MG 726
G
Sbjct: 197 FG 198
>BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 83.8 bits (198), Expect = 8e-16
Identities = 51/182 (28%), Positives = 86/182 (47%), Gaps = 2/182 (1%)
Frame = +1
Query: 187 LLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQT 366
+LG I +L R Q + K + PGP +FG+AL + + V + +A
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 367 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 546
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 547 HRKMIAPTFHINILKSFVGIFNQNSNNVVEKL--KSEVGKTFDVHDYMSGTTVDILLETA 720
HRK++ P FH ++LK +V +F +++ +++K K+ GK+FD+ + ++ L++
Sbjct: 137 HRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCT 196
Query: 721 MG 726
G
Sbjct: 197 FG 198
>AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P450
4B1 protein.
Length = 512
Score = 83.8 bits (198), Expect = 8e-16
Identities = 51/182 (28%), Positives = 86/182 (47%), Gaps = 2/182 (1%)
Frame = +1
Query: 187 LLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQT 366
+LG I +L R Q + K + PGP +FG+AL + + V + +A
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 367 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 546
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 547 HRKMIAPTFHINILKSFVGIFNQNSNNVVEKL--KSEVGKTFDVHDYMSGTTVDILLETA 720
HRK++ P FH ++LK +V +F +++ +++K K+ GK+FD+ + ++ L++
Sbjct: 137 HRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCT 196
Query: 721 MG 726
G
Sbjct: 197 FG 198
>AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 83.8 bits (198), Expect = 8e-16
Identities = 51/182 (28%), Positives = 86/182 (47%), Gaps = 2/182 (1%)
Frame = +1
Query: 187 LLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQT 366
+LG I +L R Q + K + PGP +FG+AL + + V + +A
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 367 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 546
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 547 HRKMIAPTFHINILKSFVGIFNQNSNNVVEKL--KSEVGKTFDVHDYMSGTTVDILLETA 720
HRK++ P FH ++LK +V +F +++ +++K K+ GK+FD+ + ++ L++
Sbjct: 137 HRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCT 196
Query: 721 MG 726
G
Sbjct: 197 FG 198
>AY064484-1|AAL57719.1| 295|Homo sapiens truncated cytochrome P450
protein.
Length = 295
Score = 83.8 bits (198), Expect = 8e-16
Identities = 51/182 (28%), Positives = 86/182 (47%), Gaps = 2/182 (1%)
Frame = +1
Query: 187 LLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQT 366
+LG I +L R Q + K + PGP +FG+AL + + V + +A
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 367 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 546
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 547 HRKMIAPTFHINILKSFVGIFNQNSNNVVEKL--KSEVGKTFDVHDYMSGTTVDILLETA 720
HRK++ P FH ++LK +V +F +++ +++K K+ GK+FD+ + ++ L++
Sbjct: 137 HRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCT 196
Query: 721 MG 726
G
Sbjct: 197 FG 198
>AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 83.8 bits (198), Expect = 8e-16
Identities = 51/182 (28%), Positives = 86/182 (47%), Gaps = 2/182 (1%)
Frame = +1
Query: 187 LLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQT 366
+LG I +L R Q + K + PGP +FG+AL + + V + +A
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 367 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 546
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 547 HRKMIAPTFHINILKSFVGIFNQNSNNVVEKL--KSEVGKTFDVHDYMSGTTVDILLETA 720
HRK++ P FH ++LK +V +F +++ +++K K+ GK+FD+ + ++ L++
Sbjct: 137 HRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCT 196
Query: 721 MG 726
G
Sbjct: 197 FG 198
>AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 83.8 bits (198), Expect = 8e-16
Identities = 51/182 (28%), Positives = 86/182 (47%), Gaps = 2/182 (1%)
Frame = +1
Query: 187 LLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQT 366
+LG I +L R Q + K + PGP +FG+AL + + V + +A
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 367 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 546
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 547 HRKMIAPTFHINILKSFVGIFNQNSNNVVEKL--KSEVGKTFDVHDYMSGTTVDILLETA 720
HRK++ P FH ++LK +V +F +++ +++K K+ GK+FD+ + ++ L++
Sbjct: 137 HRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCT 196
Query: 721 MG 726
G
Sbjct: 197 FG 198
>AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 83.8 bits (198), Expect = 8e-16
Identities = 51/182 (28%), Positives = 86/182 (47%), Gaps = 2/182 (1%)
Frame = +1
Query: 187 LLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQT 366
+LG I +L R Q + K + PGP +FG+AL + + V + +A
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 367 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 546
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 547 HRKMIAPTFHINILKSFVGIFNQNSNNVVEKL--KSEVGKTFDVHDYMSGTTVDILLETA 720
HRK++ P FH ++LK +V +F +++ +++K K+ GK+FD+ + ++ L++
Sbjct: 137 HRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCT 196
Query: 721 MG 726
G
Sbjct: 197 FG 198
>AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 83.8 bits (198), Expect = 8e-16
Identities = 51/182 (28%), Positives = 86/182 (47%), Gaps = 2/182 (1%)
Frame = +1
Query: 187 LLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQT 366
+LG I +L R Q + K + PGP +FG+AL + + V + +A
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 367 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 546
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 547 HRKMIAPTFHINILKSFVGIFNQNSNNVVEKL--KSEVGKTFDVHDYMSGTTVDILLETA 720
HRK++ P FH ++LK +V +F +++ +++K K+ GK+FD+ + ++ L++
Sbjct: 137 HRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCT 196
Query: 721 MG 726
G
Sbjct: 197 FG 198
>AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens
cDNA FLJ39501 fis, clone PROST2016980, moderately
similar to CYTOCHROME P450 4F2 (EC 1.14.13.30). ).
Length = 531
Score = 83.8 bits (198), Expect = 8e-16
Identities = 48/150 (32%), Positives = 82/150 (54%), Gaps = 6/150 (4%)
Frame = +1
Query: 373 NVVRVWLGSKL-IVFLADADDIEIILNSHVHIDKATE--YKFFKPWLGEGLLISSGPKWR 543
+V+ VW+G L ++ L D I+ +L + + Y F KPWLG+GLL+S G KW
Sbjct: 94 HVLLVWMGPVLPLLVLVHPDYIKPLLGASAATAPKDDLFYGFLKPWLGDGLLLSKGDKWS 153
Query: 544 SHRKMIAPTFHINILKSFVGIFNQNSNNVVEK---LKSEVGKTFDVHDYMSGTTVDILLE 714
HR+++ P FH +ILK ++ IFNQ+++ + K L + D+ +++S T+D L +
Sbjct: 154 RHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHISLMTLDSLQK 213
Query: 715 TAMGISRKTQDESXFDYAMAVMKCAISSTK 804
+ Q E DY A+++ + S +
Sbjct: 214 CVFSYNSNCQ-EKMSDYISAIIELSALSVR 242
>AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 83.8 bits (198), Expect = 8e-16
Identities = 51/182 (28%), Positives = 86/182 (47%), Gaps = 2/182 (1%)
Frame = +1
Query: 187 LLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQT 366
+LG I +L R Q + K + PGP +FG+AL + + V + +A
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 367 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 546
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 547 HRKMIAPTFHINILKSFVGIFNQNSNNVVEKL--KSEVGKTFDVHDYMSGTTVDILLETA 720
HRK++ P FH ++LK +V +F +++ +++K K+ GK+FD+ + ++ L++
Sbjct: 137 HRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCT 196
Query: 721 MG 726
G
Sbjct: 197 FG 198
>AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 83.0 bits (196), Expect = 1e-15
Identities = 50/182 (27%), Positives = 86/182 (47%), Gaps = 2/182 (1%)
Frame = +1
Query: 187 LLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQT 366
+LG I +L R Q + K + PGP +FG+AL + + V + +A
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 367 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 546
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 547 HRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV--GKTFDVHDYMSGTTVDILLETA 720
HRK++ P FH ++LK +V +F +++ +++K + + GK+FD+ + ++ L++
Sbjct: 137 HRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAWEGKSFDIFCDVGHMALNTLMKCT 196
Query: 721 MG 726
G
Sbjct: 197 FG 198
>J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung
cytochrome P450 (IV subfamily) BI protein, complete cds.
).
Length = 511
Score = 82.2 bits (194), Expect = 2e-15
Identities = 50/182 (27%), Positives = 86/182 (47%), Gaps = 2/182 (1%)
Frame = +1
Query: 187 LLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQT 366
+LG I +L R + + K + PGP +FG+AL + + V + +A
Sbjct: 23 VLGFLKLIHLLLRRRT---LAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 367 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 546
F +W G + D + S Y FF W+G GLL+ GPKW
Sbjct: 77 FPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQ 136
Query: 547 HRKMIAPTFHINILKSFVGIFNQNSNNVVEKL--KSEVGKTFDVHDYMSGTTVDILLETA 720
HRK++ P FH ++LK +V +F +++ +++K K+ GK+FD+ + ++ L++
Sbjct: 137 HRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCT 196
Query: 721 MG 726
G
Sbjct: 197 FG 198
>AF221943-1|AAF86378.1| 175|Homo sapiens leukotriene B4 omega
hydroxylase protein.
Length = 175
Score = 79.4 bits (187), Expect = 2e-14
Identities = 40/100 (40%), Positives = 58/100 (58%), Gaps = 3/100 (3%)
Frame = +1
Query: 334 LVNLALGYAQTFGNVVRVWLGS-KLIVFLADADDIEIILNSHVHIDKATE--YKFFKPWL 504
L L Y Q F +VW+G ++ L D I ++N+ I + Y F +PWL
Sbjct: 77 LTQLVATYPQGF----KVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWL 132
Query: 505 GEGLLISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSN 624
G+GLL+S+G KW HR+M+ P FH NILK ++ IFN++ N
Sbjct: 133 GDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVN 172
>S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 591
Score = 78.2 bits (184), Expect = 4e-14
Identities = 50/180 (27%), Positives = 89/180 (49%), Gaps = 4/180 (2%)
Frame = +1
Query: 250 KLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVVRVWL-GSKLIVFLADA 426
K + P P +FG+ L + + + + +TF + WL G K+ V L D
Sbjct: 46 KALQQFPCPPSHWLFGHIQELQQDQELQRIQK---WVETFPSACPHWLWGGKVRVQLYDP 102
Query: 427 DDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGI 606
D +++IL + Y+F PW+G GLL+ +G W HR+M+ P FH +ILK +VG+
Sbjct: 103 DYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVGL 161
Query: 607 FNQNSNNVVEKLKSEVGK--TFDVHDYMSGTTVDILLETAMGISRKTQ-DESXFDYAMAV 777
+ +++K + +G+ +V ++S T+D +++ A Q D + Y A+
Sbjct: 162 MADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRNSQSYIQAI 221
>S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 519
Score = 78.2 bits (184), Expect = 4e-14
Identities = 50/180 (27%), Positives = 89/180 (49%), Gaps = 4/180 (2%)
Frame = +1
Query: 250 KLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVVRVWL-GSKLIVFLADA 426
K + P P +FG+ L + + + + +TF + WL G K+ V L D
Sbjct: 46 KALQQFPCPPSHWLFGHIQELQQDQELQRIQK---WVETFPSACPHWLWGGKVRVQLYDP 102
Query: 427 DDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGI 606
D +++IL + Y+F PW+G GLL+ +G W HR+M+ P FH +ILK +VG+
Sbjct: 103 DYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVGL 161
Query: 607 FNQNSNNVVEKLKSEVGK--TFDVHDYMSGTTVDILLETAMGISRKTQ-DESXFDYAMAV 777
+ +++K + +G+ +V ++S T+D +++ A Q D + Y A+
Sbjct: 162 MADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRNSQSYIQAI 221
>L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein.
Length = 519
Score = 78.2 bits (184), Expect = 4e-14
Identities = 50/180 (27%), Positives = 89/180 (49%), Gaps = 4/180 (2%)
Frame = +1
Query: 250 KLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVVRVWL-GSKLIVFLADA 426
K + P P +FG+ L + + + + +TF + WL G K+ V L D
Sbjct: 46 KALQQFPCPPSHWLFGHIQELQQDQELQRIQK---WVETFPSACPHWLWGGKVRVQLYDP 102
Query: 427 DDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGI 606
D +++IL + Y+F PW+G GLL+ +G W HR+M+ P FH +ILK +VG+
Sbjct: 103 DYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVGL 161
Query: 607 FNQNSNNVVEKLKSEVGK--TFDVHDYMSGTTVDILLETAMGISRKTQ-DESXFDYAMAV 777
+ +++K + +G+ +V ++S T+D +++ A Q D + Y A+
Sbjct: 162 MADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRNSQSYIQAI 221
>D26481-1|BAA05491.1| 519|Homo sapiens fatty acids
omega-hydroxylase protein.
Length = 519
Score = 78.2 bits (184), Expect = 4e-14
Identities = 50/180 (27%), Positives = 89/180 (49%), Gaps = 4/180 (2%)
Frame = +1
Query: 250 KLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVVRVWL-GSKLIVFLADA 426
K + P P +FG+ L + + + + +TF + WL G K+ V L D
Sbjct: 46 KALQQFPCPPSHWLFGHIQELQQDQELQRIQK---WVETFPSACPHWLWGGKVRVQLYDP 102
Query: 427 DDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGI 606
D +++IL + Y+F PW+G GLL+ +G W HR+M+ P FH +ILK +VG+
Sbjct: 103 DYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVGL 161
Query: 607 FNQNSNNVVEKLKSEVGK--TFDVHDYMSGTTVDILLETAMGISRKTQ-DESXFDYAMAV 777
+ +++K + +G+ +V ++S T+D +++ A Q D + Y A+
Sbjct: 162 MADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRNSQSYIQAI 221
>D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 521
Score = 78.2 bits (184), Expect = 4e-14
Identities = 50/180 (27%), Positives = 89/180 (49%), Gaps = 4/180 (2%)
Frame = +1
Query: 250 KLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVVRVWL-GSKLIVFLADA 426
K + P P +FG+ L + + + + +TF + WL G K+ V L D
Sbjct: 46 KALQQFPCPPSHWLFGHIQELQQDQELQRIQK---WVETFPSACPHWLWGGKVRVQLYDP 102
Query: 427 DDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGI 606
D +++IL + Y+F PW+G GLL+ +G W HR+M+ P FH +ILK +VG+
Sbjct: 103 DYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVGL 161
Query: 607 FNQNSNNVVEKLKSEVGK--TFDVHDYMSGTTVDILLETAMGISRKTQ-DESXFDYAMAV 777
+ +++K + +G+ +V ++S T+D +++ A Q D + Y A+
Sbjct: 162 MADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRNSQSYIQAI 221
>BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein.
Length = 455
Score = 78.2 bits (184), Expect = 4e-14
Identities = 50/180 (27%), Positives = 89/180 (49%), Gaps = 4/180 (2%)
Frame = +1
Query: 250 KLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVVRVWL-GSKLIVFLADA 426
K + P P +FG+ L + + + + +TF + WL G K+ V L D
Sbjct: 46 KALQQFPCPPSHWLFGHIQELQQDQELQRIQK---WVETFPSACPHWLWGGKVRVQLYDP 102
Query: 427 DDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGI 606
D +++IL + Y+F PW+G GLL+ +G W HR+M+ P FH +ILK +VG+
Sbjct: 103 DYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVGL 161
Query: 607 FNQNSNNVVEKLKSEVGK--TFDVHDYMSGTTVDILLETAMGISRKTQ-DESXFDYAMAV 777
+ +++K + +G+ +V ++S T+D +++ A Q D + Y A+
Sbjct: 162 MADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRNSQSYIQAI 221
>AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 78.2 bits (184), Expect = 4e-14
Identities = 50/180 (27%), Positives = 89/180 (49%), Gaps = 4/180 (2%)
Frame = +1
Query: 250 KLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVVRVWL-GSKLIVFLADA 426
K + P P +FG+ L + + + + +TF + WL G K+ V L D
Sbjct: 46 KALQQFPCPPSHWLFGHIQELQQDQELQRIQK---WVETFPSACPHWLWGGKVRVQLYDP 102
Query: 427 DDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGI 606
D +++IL + Y+F PW+G GLL+ +G W HR+M+ P FH +ILK +VG+
Sbjct: 103 DYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVGL 161
Query: 607 FNQNSNNVVEKLKSEVGK--TFDVHDYMSGTTVDILLETAMGISRKTQ-DESXFDYAMAV 777
+ +++K + +G+ +V ++S T+D +++ A Q D + Y A+
Sbjct: 162 MADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRNSQSYIQAI 221
>AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 455
Score = 78.2 bits (184), Expect = 4e-14
Identities = 50/180 (27%), Positives = 89/180 (49%), Gaps = 4/180 (2%)
Frame = +1
Query: 250 KLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVVRVWL-GSKLIVFLADA 426
K + P P +FG+ L + + + + +TF + WL G K+ V L D
Sbjct: 46 KALQQFPCPPSHWLFGHIQELQQDQELQRIQK---WVETFPSACPHWLWGGKVRVQLYDP 102
Query: 427 DDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGI 606
D +++IL + Y+F PW+G GLL+ +G W HR+M+ P FH +ILK +VG+
Sbjct: 103 DYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVGL 161
Query: 607 FNQNSNNVVEKLKSEVGK--TFDVHDYMSGTTVDILLETAMGISRKTQ-DESXFDYAMAV 777
+ +++K + +G+ +V ++S T+D +++ A Q D + Y A+
Sbjct: 162 MADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRNSQSYIQAI 221
>AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 78.2 bits (184), Expect = 4e-14
Identities = 50/180 (27%), Positives = 89/180 (49%), Gaps = 4/180 (2%)
Frame = +1
Query: 250 KLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVVRVWL-GSKLIVFLADA 426
K + P P +FG+ L + + + + +TF + WL G K+ V L D
Sbjct: 46 KALQQFPCPPSHWLFGHIQELQQDQELQRIQK---WVETFPSACPHWLWGGKVRVQLYDP 102
Query: 427 DDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGI 606
D +++IL + Y+F PW+G GLL+ +G W HR+M+ P FH +ILK +VG+
Sbjct: 103 DYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVGL 161
Query: 607 FNQNSNNVVEKLKSEVGK--TFDVHDYMSGTTVDILLETAMGISRKTQ-DESXFDYAMAV 777
+ +++K + +G+ +V ++S T+D +++ A Q D + Y A+
Sbjct: 162 MADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRNSQSYIQAI 221
>AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfamily
IVA, polypeptide 11 protein.
Length = 519
Score = 78.2 bits (184), Expect = 4e-14
Identities = 50/180 (27%), Positives = 89/180 (49%), Gaps = 4/180 (2%)
Frame = +1
Query: 250 KLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVVRVWL-GSKLIVFLADA 426
K + P P +FG+ L + + + + +TF + WL G K+ V L D
Sbjct: 46 KALQQFPCPPSHWLFGHIQELQQDQELQRIQK---WVETFPSACPHWLWGGKVRVQLYDP 102
Query: 427 DDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGI 606
D +++IL + Y+F PW+G GLL+ +G W HR+M+ P FH +ILK +VG+
Sbjct: 103 DYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVGL 161
Query: 607 FNQNSNNVVEKLKSEVGK--TFDVHDYMSGTTVDILLETAMGISRKTQ-DESXFDYAMAV 777
+ +++K + +G+ +V ++S T+D +++ A Q D + Y A+
Sbjct: 162 MADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRNSQSYIQAI 221
>BC022851-1|AAH22851.1| 215|Homo sapiens CYP4A11 protein protein.
Length = 215
Score = 76.6 bits (180), Expect = 1e-13
Identities = 46/160 (28%), Positives = 83/160 (51%), Gaps = 3/160 (1%)
Frame = +1
Query: 250 KLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVVRVWL-GSKLIVFLADA 426
K + P P +FG+ L + + + + +TF + WL G K+ V L D
Sbjct: 46 KALQQFPCPPSHWLFGHIQELQQDQELQRIQK---WVETFPSACPHWLWGGKVRVQLYDP 102
Query: 427 DDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVGI 606
D +++IL + Y+F PW+G GLL+ +G W HR+M+ P FH +ILK +VG+
Sbjct: 103 DYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVGL 161
Query: 607 FNQNSNNVVEKLKSEVGK--TFDVHDYMSGTTVDILLETA 720
+ +++K + +G+ +V ++S T+D +++ A
Sbjct: 162 MADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCA 201
>BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 74.1 bits (174), Expect = 6e-13
Identities = 59/212 (27%), Positives = 102/212 (48%), Gaps = 9/212 (4%)
Frame = +1
Query: 175 IFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIP--IFGNALTLMRKSPHELVNLA 348
+F LGL AI + R Q+ L +L P PAP G+ + + +L +
Sbjct: 19 VFCLALGLLQAIKLYLRRQR-----LLRDLRPFPAPPTHWFLGHQKFIQDDNMEKLEEII 73
Query: 349 LGYAQTFGNVVRVWLGSKLIVF-LADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLL 519
Y + F W+G F + D D + +L+ D ++Y KF P LG+GL
Sbjct: 74 EKYPRAFP----FWIGPFQAFFCIYDPDYAKTLLS---RTDPKSQYLQKFSPPLLGKGLA 126
Query: 520 ISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVV---EKLKSEVGKTFDVHDYMSG 690
GPKW HR+++ P FH NILK+++ + + ++ EK+ S + +V+++++
Sbjct: 127 ALDGPKWFQHRRLLTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINS 186
Query: 691 TTVDILLETAMGISRKTQDESXFD-YAMAVMK 783
++DI+++ A Q S D YA A+ +
Sbjct: 187 MSLDIIMKCAFSKETNCQTNSTHDPYAKAIFE 218
>AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein.
Length = 509
Score = 74.1 bits (174), Expect = 6e-13
Identities = 59/212 (27%), Positives = 102/212 (48%), Gaps = 9/212 (4%)
Frame = +1
Query: 175 IFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIP--IFGNALTLMRKSPHELVNLA 348
+F LGL AI + R Q+ L +L P PAP G+ + + +L +
Sbjct: 19 VFCLALGLLQAIKLYLRRQR-----LLRDLRPFPAPPTHWFLGHQKFIQDDNMEKLEEII 73
Query: 349 LGYAQTFGNVVRVWLGSKLIVF-LADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLL 519
Y + F W+G F + D D + +L+ D ++Y KF P LG+GL
Sbjct: 74 EKYPRAFP----FWIGPFQAFFCIYDPDYAKTLLS---RTDPKSQYLQKFSPPLLGKGLA 126
Query: 520 ISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVV---EKLKSEVGKTFDVHDYMSG 690
GPKW HR+++ P FH NILK+++ + + ++ EK+ S + +V+++++
Sbjct: 127 ALDGPKWFQHRRLLTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINS 186
Query: 691 TTVDILLETAMGISRKTQDESXFD-YAMAVMK 783
++DI+++ A Q S D YA A+ +
Sbjct: 187 MSLDIIMKCAFSKETNCQTNSTHDPYAKAIFE 218
>AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22
protein.
Length = 519
Score = 74.1 bits (174), Expect = 6e-13
Identities = 42/143 (29%), Positives = 75/143 (52%), Gaps = 4/143 (2%)
Frame = +1
Query: 361 QTFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPK 537
+TF + W+ G K+ V L D D +++IL + YKF PW+G LL+ +G
Sbjct: 80 KTFPSACPYWIWGGKVRVQLYDPDYMKVILGRSDSKSHGS-YKFLAPWIGYSLLLLNGQT 138
Query: 538 WRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK--TFDVHDYMSGTTVDILL 711
W HR+M+ P FH +ILK +VG+ + +++K + +G+ + ++S T+D ++
Sbjct: 139 WFQHRRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEFFQHVSLMTLDTIM 198
Query: 712 ETAMGISRKTQ-DESXFDYAMAV 777
++A Q D + Y A+
Sbjct: 199 KSAFSHQGSIQVDRNSQSYIQAI 221
>AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein.
Length = 509
Score = 74.1 bits (174), Expect = 6e-13
Identities = 59/212 (27%), Positives = 102/212 (48%), Gaps = 9/212 (4%)
Frame = +1
Query: 175 IFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIP--IFGNALTLMRKSPHELVNLA 348
+F LGL AI + R Q+ L +L P PAP G+ + + +L +
Sbjct: 19 VFCLALGLLQAIKLYLRRQR-----LLRDLRPFPAPPTHWFLGHQKFIQDDNMEKLEEII 73
Query: 349 LGYAQTFGNVVRVWLGSKLIVF-LADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLL 519
Y + F W+G F + D D + +L+ D ++Y KF P LG+GL
Sbjct: 74 EKYPRAFP----FWIGPFQAFFCIYDPDYAKTLLS---RTDPKSQYLQKFSPPLLGKGLA 126
Query: 520 ISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVV---EKLKSEVGKTFDVHDYMSG 690
GPKW HR+++ P FH NILK+++ + + ++ EK+ S + +V+++++
Sbjct: 127 ALDGPKWFQHRRLLTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINS 186
Query: 691 TTVDILLETAMGISRKTQDESXFD-YAMAVMK 783
++DI+++ A Q S D YA A+ +
Sbjct: 187 MSLDIIMKCAFSKETNCQTNSTHDPYAKAIFE 218
>AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 74.1 bits (174), Expect = 6e-13
Identities = 59/212 (27%), Positives = 102/212 (48%), Gaps = 9/212 (4%)
Frame = +1
Query: 175 IFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIP--IFGNALTLMRKSPHELVNLA 348
+F LGL AI + R Q+ L +L P PAP G+ + + +L +
Sbjct: 19 VFCLALGLLQAIKLYLRRQR-----LLRDLRPFPAPPTHWFLGHQKFIQDDNMEKLEEII 73
Query: 349 LGYAQTFGNVVRVWLGSKLIVF-LADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLL 519
Y + F W+G F + D D + +L+ D ++Y KF P LG+GL
Sbjct: 74 EKYPRAFP----FWIGPFQAFFCIYDPDYAKTLLS---RTDPKSQYLQKFSPPLLGKGLA 126
Query: 520 ISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVV---EKLKSEVGKTFDVHDYMSG 690
GPKW HR+++ P FH NILK+++ + + ++ EK+ S + +V+++++
Sbjct: 127 ALDGPKWFQHRRLLTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINS 186
Query: 691 TTVDILLETAMGISRKTQDESXFD-YAMAVMK 783
++DI+++ A Q S D YA A+ +
Sbjct: 187 MSLDIIMKCAFSKETNCQTNSTHDPYAKAIFE 218
>AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens
cDNA FLJ40746 fis, clone TRACH2000359, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 509
Score = 74.1 bits (174), Expect = 6e-13
Identities = 59/212 (27%), Positives = 102/212 (48%), Gaps = 9/212 (4%)
Frame = +1
Query: 175 IFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIP--IFGNALTLMRKSPHELVNLA 348
+F LGL AI + R Q+ L +L P PAP G+ + + +L +
Sbjct: 19 VFCLALGLLQAIKLYLRRQR-----LLRDLRPFPAPPTHWFLGHQKFIQDDNMEKLEEII 73
Query: 349 LGYAQTFGNVVRVWLGSKLIVF-LADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLL 519
Y + F W+G F + D D + +L+ D ++Y KF P LG+GL
Sbjct: 74 EKYPRAFP----FWIGPFQAFFCIYDPDYAKTLLS---RTDPKSQYLQKFSPPLLGKGLA 126
Query: 520 ISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVV---EKLKSEVGKTFDVHDYMSG 690
GPKW HR+++ P FH NILK+++ + + ++ EK+ S + +V+++++
Sbjct: 127 ALDGPKWFQHRRLLTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINS 186
Query: 691 TTVDILLETAMGISRKTQDESXFD-YAMAVMK 783
++DI+++ A Q S D YA A+ +
Sbjct: 187 MSLDIIMKCAFSKETNCQTNSTHDPYAKAIFE 218
>BC142607-1|AAI42608.1| 455|Homo sapiens CYP4A22 protein protein.
Length = 455
Score = 73.7 bits (173), Expect = 8e-13
Identities = 42/143 (29%), Positives = 75/143 (52%), Gaps = 4/143 (2%)
Frame = +1
Query: 361 QTFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPK 537
+TF + W+ G K+ V L D D +++IL + YKF PW+G LL+ +G
Sbjct: 80 KTFPSACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPWIGYSLLLLNGQT 138
Query: 538 WRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK--TFDVHDYMSGTTVDILL 711
W HR+M+ P FH +ILK +VG+ + +++K + +G+ + ++S T+D ++
Sbjct: 139 WFQHRRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEFFQHVSLMTLDTIM 198
Query: 712 ETAMGISRKTQ-DESXFDYAMAV 777
++A Q D + Y A+
Sbjct: 199 KSAFSHQGSIQVDRNSQSYIQAI 221
>AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K
protein.
Length = 519
Score = 73.7 bits (173), Expect = 8e-13
Identities = 42/143 (29%), Positives = 75/143 (52%), Gaps = 4/143 (2%)
Frame = +1
Query: 361 QTFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPK 537
+TF + W+ G K+ V L D D +++IL + YKF PW+G LL+ +G
Sbjct: 80 KTFPSACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPWIGYSLLLLNGQT 138
Query: 538 WRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK--TFDVHDYMSGTTVDILL 711
W HR+M+ P FH +ILK +VG+ + +++K + +G+ + ++S T+D ++
Sbjct: 139 WFQHRRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEFFQHVSLMTLDTIM 198
Query: 712 ETAMGISRKTQ-DESXFDYAMAV 777
++A Q D + Y A+
Sbjct: 199 KSAFSHQGSIQVDRNSQSYIQAI 221
>AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 455
Score = 71.7 bits (168), Expect = 3e-12
Identities = 43/143 (30%), Positives = 76/143 (53%), Gaps = 4/143 (2%)
Frame = +1
Query: 361 QTFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPK 537
+TF + W+ G K+ V L D D +++IL + YKF P +G GLL+ +G
Sbjct: 80 KTFPSACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPRIGYGLLLLNGQT 138
Query: 538 WRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK--TFDVHDYMSGTTVDILL 711
W HR+M+ P FH +ILK +VG+ + +++K + +G+ +V ++S T+D ++
Sbjct: 139 WFQHRRMLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIM 198
Query: 712 ETAMGISRKTQ-DESXFDYAMAV 777
++A Q D + Y A+
Sbjct: 199 KSAFSHQGSIQVDRNSQSYIQAI 221
>AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 22 protein.
Length = 519
Score = 71.7 bits (168), Expect = 3e-12
Identities = 43/143 (30%), Positives = 76/143 (53%), Gaps = 4/143 (2%)
Frame = +1
Query: 361 QTFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPK 537
+TF + W+ G K+ V L D D +++IL + YKF P +G GLL+ +G
Sbjct: 80 KTFPSACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPRIGYGLLLLNGQT 138
Query: 538 WRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK--TFDVHDYMSGTTVDILL 711
W HR+M+ P FH +ILK +VG+ + +++K + +G+ +V ++S T+D ++
Sbjct: 139 WFQHRRMLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIM 198
Query: 712 ETAMGISRKTQ-DESXFDYAMAV 777
++A Q D + Y A+
Sbjct: 199 KSAFSHQGSIQVDRNSQSYIQAI 221
>BC142690-1|AAI42691.1| 357|Homo sapiens CYP4A22 protein protein.
Length = 357
Score = 70.9 bits (166), Expect = 6e-12
Identities = 39/123 (31%), Positives = 70/123 (56%), Gaps = 3/123 (2%)
Frame = +1
Query: 361 QTFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPK 537
+TF + W+ G K+ V L D D +++IL + YKF P +G GLL+ +G
Sbjct: 80 KTFPSACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPRIGYGLLLLNGQT 138
Query: 538 WRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK--TFDVHDYMSGTTVDILL 711
W HR+M+ P FH +ILK +VG+ + +++K + +G+ +V ++S T+D ++
Sbjct: 139 WFQHRRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIM 198
Query: 712 ETA 720
++A
Sbjct: 199 KSA 201
>AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid
omega-hydroxylase CYP4A11 protein.
Length = 519
Score = 70.5 bits (165), Expect = 8e-12
Identities = 42/143 (29%), Positives = 76/143 (53%), Gaps = 4/143 (2%)
Frame = +1
Query: 361 QTFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPK 537
+TF + W+ G K+ V L D D +++IL + Y+F P +G GLL+ +G
Sbjct: 80 KTFPSACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPRIGYGLLLLNGQT 138
Query: 538 WRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK--TFDVHDYMSGTTVDILL 711
W HR+M+ P FH +ILK +VG+ + +++K + +G+ +V ++S T+D ++
Sbjct: 139 WFQHRRMLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIM 198
Query: 712 ETAMGISRKTQ-DESXFDYAMAV 777
++A Q D + Y A+
Sbjct: 199 KSAFSHQGSIQVDRNSQSYIQAI 221
>AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 421
Score = 70.1 bits (164), Expect = 1e-11
Identities = 39/123 (31%), Positives = 70/123 (56%), Gaps = 3/123 (2%)
Frame = +1
Query: 361 QTFGNVVRVWL-GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPK 537
+TF + W+ G K+ V L D D +++IL + YKF P +G GLL+ +G
Sbjct: 80 KTFPSACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YKFLAPRIGYGLLLLNGQT 138
Query: 538 WRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGK--TFDVHDYMSGTTVDILL 711
W HR+M+ P FH +ILK +VG+ + +++K + +G+ +V ++S T+D ++
Sbjct: 139 WFQHRRMLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIM 198
Query: 712 ETA 720
++A
Sbjct: 199 KSA 201
>AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens
cDNA FLJ34487 fis, clone HLUNG2004273, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 444
Score = 69.7 bits (163), Expect = 1e-11
Identities = 41/139 (29%), Positives = 74/139 (53%), Gaps = 7/139 (5%)
Frame = +1
Query: 388 WLGSKLIVF-LADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLLISSGPKWRSHRKM 558
W+G F + D D + +L+ D ++Y KF P LG+GL GPKW HR++
Sbjct: 18 WIGPFQAFFCIYDPDYAKTLLS---RTDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 74
Query: 559 IAPTFHINILKSFVGIFNQNSNNVV---EKLKSEVGKTFDVHDYMSGTTVDILLETAMGI 729
+ P FH NILK+++ + + ++ EK+ S + +V+++++ ++DI+++ A
Sbjct: 75 LTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSK 134
Query: 730 SRKTQDESXFD-YAMAVMK 783
Q S D YA A+ +
Sbjct: 135 ETNCQTNSTHDPYAKAIFE 153
>AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens
cDNA FLJ16384 fis, clone TLIVE2007607, weakly similar
to CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 508
Score = 69.3 bits (162), Expect = 2e-11
Identities = 41/139 (29%), Positives = 74/139 (53%), Gaps = 7/139 (5%)
Frame = +1
Query: 388 WLGSKLIVF-LADADDIEIILNSHVHIDKATEY--KFFKPWLGEGLLISSGPKWRSHRKM 558
W+G F + D D + +L+ D ++Y KF P LG+GL GPKW HR++
Sbjct: 82 WIGPFQAFFCIYDPDYAKTLLS---RTDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRL 138
Query: 559 IAPTFHINILKSFVGIFNQNSNNVV---EKLKSEVGKTFDVHDYMSGTTVDILLETAMGI 729
+ P FH NILK+++ + + ++ EK+ S + +V+++++ ++DI+++ A
Sbjct: 139 LTPGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIVMKCAFSK 198
Query: 730 SRKTQDESXFD-YAMAVMK 783
Q S D YA A+ +
Sbjct: 199 ETNCQTNSTHDPYAKAIFE 217
>AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein.
Length = 505
Score = 68.5 bits (160), Expect = 3e-11
Identities = 43/171 (25%), Positives = 80/171 (46%), Gaps = 3/171 (1%)
Frame = +1
Query: 379 VRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKM 558
V +W+G + F D IL A +K + W+G GL+ G KW+ HR++
Sbjct: 80 VPLWVGPFTMFFSVHDPDYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQI 139
Query: 559 IAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKT--FDVHDYMSGTTVDILLETAMGIS 732
+ P F+I+ILK F+ + +++ ++ K + + + ++ ++S T+D +++ A
Sbjct: 140 VKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAFSHQ 199
Query: 733 RKTQDESXFD-YAMAVMKCAISSTKXTTNLGCEPRMFQVDFVFNTTNFGXI 882
Q +S D Y AV + S + N + D VF ++ G I
Sbjct: 200 GSIQLDSTLDSYLKAVFNLSKISNQRMNNF-----LHHNDLVFKFSSQGQI 245
>AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein.
Length = 505
Score = 68.5 bits (160), Expect = 3e-11
Identities = 43/171 (25%), Positives = 80/171 (46%), Gaps = 3/171 (1%)
Frame = +1
Query: 379 VRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKM 558
V +W+G + F D IL A +K + W+G GL+ G KW+ HR++
Sbjct: 80 VPLWVGPFTMFFSVHDPDYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQI 139
Query: 559 IAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKT--FDVHDYMSGTTVDILLETAMGIS 732
+ P F+I+ILK F+ + +++ ++ K + + + ++ ++S T+D +++ A
Sbjct: 140 VKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAFSHQ 199
Query: 733 RKTQDESXFD-YAMAVMKCAISSTKXTTNLGCEPRMFQVDFVFNTTNFGXI 882
Q +S D Y AV + S + N + D VF ++ G I
Sbjct: 200 GSIQLDSTLDSYLKAVFNLSKISNQRMNNF-----LHHNDLVFKFSSQGQI 245
>AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 68.5 bits (160), Expect = 3e-11
Identities = 43/171 (25%), Positives = 80/171 (46%), Gaps = 3/171 (1%)
Frame = +1
Query: 379 VRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKM 558
V +W+G + F D IL A +K + W+G GL+ G KW+ HR++
Sbjct: 80 VPLWVGPFTMFFSVHDPDYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQI 139
Query: 559 IAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKT--FDVHDYMSGTTVDILLETAMGIS 732
+ P F+I+ILK F+ + +++ ++ K + + + ++ ++S T+D +++ A
Sbjct: 140 VKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAFSHQ 199
Query: 733 RKTQDESXFD-YAMAVMKCAISSTKXTTNLGCEPRMFQVDFVFNTTNFGXI 882
Q +S D Y AV + S + N + D VF ++ G I
Sbjct: 200 GSIQLDSTLDSYLKAVFNLSKISNQRMNNF-----LHHNDLVFKFSSQGQI 245
>AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 68.5 bits (160), Expect = 3e-11
Identities = 43/171 (25%), Positives = 80/171 (46%), Gaps = 3/171 (1%)
Frame = +1
Query: 379 VRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKM 558
V +W+G + F D IL A +K + W+G GL+ G KW+ HR++
Sbjct: 80 VPLWVGPFTMFFSVHDPDYAKILLKRQDPKSAVSHKILESWVGRGLVTLDGSKWKKHRQI 139
Query: 559 IAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKT--FDVHDYMSGTTVDILLETAMGIS 732
+ P F+I+ILK F+ + +++ ++ K + + + ++ ++S T+D +++ A
Sbjct: 140 VKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAFSHQ 199
Query: 733 RKTQDESXFD-YAMAVMKCAISSTKXTTNLGCEPRMFQVDFVFNTTNFGXI 882
Q +S D Y AV + S + N + D VF ++ G I
Sbjct: 200 GSIQLDSTLDSYLKAVFNLSKISNQRMNNF-----LHHNDLVFKFSSQGQI 245
>AK097373-1|BAC05026.1| 340|Homo sapiens protein ( Homo sapiens
cDNA FLJ40054 fis, clone TBAES2000315, weakly similar to
CYTOCHROME P450 4A1 (EC 1.14.15.3). ).
Length = 340
Score = 68.5 bits (160), Expect = 3e-11
Identities = 44/172 (25%), Positives = 85/172 (49%), Gaps = 4/172 (2%)
Frame = +1
Query: 379 VRVWLGSKLIVF-LADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRK 555
V +W+G + F + D D ++I+L A +K + W+G GL+ G KW+ HR+
Sbjct: 80 VPLWVGPFTMFFNIHDPDYVKILLKRQ-DPKSAVSHKILESWVGRGLVTLDGSKWKKHRQ 138
Query: 556 MIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKT--FDVHDYMSGTTVDILLETAMGI 729
++ P F+I+ILK F+ + +++ ++ K + + + ++ ++S T+D +++ A
Sbjct: 139 IVKPGFNISILKIFITMMSKSVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAFSH 198
Query: 730 SRKTQDESXFD-YAMAVMKCAISSTKXTTNLGCEPRMFQVDFVFNTTNFGXI 882
Q +S D Y AV + S + N + D VF ++ G I
Sbjct: 199 QGSIQLDSTLDSYLKAVFNLSKISNQRMNNF-----LHHNDLVFKFSSQGQI 245
>AY696295-1|AAU10524.1| 292|Homo sapiens cytochrome P450 protein.
Length = 292
Score = 65.7 bits (153), Expect = 2e-10
Identities = 43/172 (25%), Positives = 84/172 (48%), Gaps = 4/172 (2%)
Frame = +1
Query: 379 VRVWLGSKLIVF-LADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRK 555
V +W+G + F + D D ++I+L + A +K + W+G GL+ G KW+ HR+
Sbjct: 80 VPLWVGPFTMFFNIHDPDYVKILLKRQ-NPKSAVSHKILESWVGRGLVTLDGSKWKKHRQ 138
Query: 556 MIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV--GKTFDVHDYMSGTTVDILLETAMGI 729
++ P F+I+ILK F+ + +++ ++ K + + ++ ++S T+ +++ A
Sbjct: 139 IVKPGFNISILKIFITMMSKSVRMMLNKWEEHIAHNSRLELFQHVSLMTLHSIMKCAFSH 198
Query: 730 SRKTQDESXFD-YAMAVMKCAISSTKXTTNLGCEPRMFQVDFVFNTTNFGXI 882
Q +S D Y AV + S + N + D VF ++ G I
Sbjct: 199 QGSIQLDSTLDSYLKAVFNLSKISNQRMNNF-----LHHNDLVFKFSSQGQI 245
>AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P450
4B1 variant protein.
Length = 497
Score = 63.7 bits (148), Expect = 9e-10
Identities = 50/182 (27%), Positives = 85/182 (46%), Gaps = 2/182 (1%)
Frame = +1
Query: 187 LLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQT 366
+LG I +L R Q + K + PGP +FG+AL + + V + +A
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 367 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 546
F +W G + I FL +I + K G GLL+ GPKW
Sbjct: 77 FPYAHPLWFG-QFIGFL--------------NIYEPDYAKAVYSRGGRGLLVLEGPKWLQ 121
Query: 547 HRKMIAPTFHINILKSFVGIFNQNSNNVVEKL--KSEVGKTFDVHDYMSGTTVDILLETA 720
HRK++ P FH ++LK +V +F +++ +++K K+ GK+FD+ + ++ L++
Sbjct: 122 HRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCT 181
Query: 721 MG 726
G
Sbjct: 182 FG 183
>AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 63.7 bits (148), Expect = 9e-10
Identities = 50/182 (27%), Positives = 85/182 (46%), Gaps = 2/182 (1%)
Frame = +1
Query: 187 LLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQT 366
+LG I +L R Q + K + PGP +FG+AL + + V + +A
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 367 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 546
F +W G + I FL +I + K G GLL+ GPKW
Sbjct: 77 FPYAHPLWFG-QFIGFL--------------NIYEPDYAKAVYSRGGRGLLVLEGPKWLQ 121
Query: 547 HRKMIAPTFHINILKSFVGIFNQNSNNVVEKL--KSEVGKTFDVHDYMSGTTVDILLETA 720
HRK++ P FH ++LK +V +F +++ +++K K+ GK+FD+ + ++ L++
Sbjct: 122 HRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCT 181
Query: 721 MG 726
G
Sbjct: 182 FG 183
>AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 63.7 bits (148), Expect = 9e-10
Identities = 50/182 (27%), Positives = 85/182 (46%), Gaps = 2/182 (1%)
Frame = +1
Query: 187 LLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQT 366
+LG I +L R Q + K + PGP +FG+AL + + V + +A
Sbjct: 23 VLGFLKLIHLLLRRQT---LAKAMDKFPGPPTHWLFGHALEIQETGSLDKV---VSWAHQ 76
Query: 367 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRS 546
F +W G + I FL +I + K G GLL+ GPKW
Sbjct: 77 FPYAHPLWFG-QFIGFL--------------NIYEPDYAKAVYSRGGRGLLVLEGPKWLQ 121
Query: 547 HRKMIAPTFHINILKSFVGIFNQNSNNVVEKL--KSEVGKTFDVHDYMSGTTVDILLETA 720
HRK++ P FH ++LK +V +F +++ +++K K+ GK+FD+ + ++ L++
Sbjct: 122 HRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCT 181
Query: 721 MG 726
G
Sbjct: 182 FG 183
>J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipine
oxidase protein.
Length = 502
Score = 61.3 bits (142), Expect = 5e-09
Identities = 45/185 (24%), Positives = 87/185 (47%), Gaps = 6/185 (3%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSH--MHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTF 369
L ++ +LY + +SH KL +PGP P+P GN L+ + + + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKG----FCMFDMECHKKY 68
Query: 370 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 543
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVCGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 544 SHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLET 717
R +++PTF LK V I Q + +V L+ +E GK + D ++D++ T
Sbjct: 128 RLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITST 187
Query: 718 AMGIS 732
+ G++
Sbjct: 188 SFGVN 192
>AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein.
Length = 503
Score = 60.9 bits (141), Expect = 6e-09
Identities = 45/185 (24%), Positives = 88/185 (47%), Gaps = 6/185 (3%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSH--MHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTF 369
+ T++ +LY + +SH KL +PGP P+P GN L+ + + + +
Sbjct: 15 VATSLVLLYIYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKG----FCMFDMECHKKY 68
Query: 370 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 543
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 544 SHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLET 717
R +++PTF LK V I Q + +V L+ +E GK + D ++D++ T
Sbjct: 128 RLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITST 187
Query: 718 AMGIS 732
+ G++
Sbjct: 188 SFGVN 192
>X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (cyp3 locus). ).
Length = 503
Score = 60.5 bits (140), Expect = 8e-09
Identities = 45/185 (24%), Positives = 87/185 (47%), Gaps = 6/185 (3%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSH--MHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTF 369
L ++ +LY + +SH KL +PGP P+P GN L+ + + + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKG----FCMFDMECHKKY 68
Query: 370 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 543
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 544 SHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLET 717
R +++PTF LK V I Q + +V L+ +E GK + D ++D++ T
Sbjct: 128 RLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITST 187
Query: 718 AMGIS 732
+ G++
Sbjct: 188 SFGVN 192
>M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA
encoding nifedipine oxidase, complete cds. ).
Length = 503
Score = 60.5 bits (140), Expect = 8e-09
Identities = 45/185 (24%), Positives = 87/185 (47%), Gaps = 6/185 (3%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSH--MHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTF 369
L ++ +LY + +SH KL +PGP P+P GN L+ + + + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKG----FCMFDMECHKKY 68
Query: 370 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 543
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 544 SHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLET 717
R +++PTF LK V I Q + +V L+ +E GK + D ++D++ T
Sbjct: 128 RLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITST 187
Query: 718 AMGIS 732
+ G++
Sbjct: 188 SFGVN 192
>M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrome
P-450 nifedipine oxidase mRNA, complet cds. ).
Length = 503
Score = 60.5 bits (140), Expect = 8e-09
Identities = 45/185 (24%), Positives = 87/185 (47%), Gaps = 6/185 (3%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSH--MHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTF 369
L ++ +LY + +SH KL +PGP P+P GN L+ + + + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKG----FCMFDMECHKKY 68
Query: 370 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 543
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 544 SHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLET 717
R +++PTF LK V I Q + +V L+ +E GK + D ++D++ T
Sbjct: 128 RLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITST 187
Query: 718 AMGIS 732
+ G++
Sbjct: 188 SFGVN 192
>DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family 3
subfamily A polypeptide 4 protein.
Length = 503
Score = 60.5 bits (140), Expect = 8e-09
Identities = 45/185 (24%), Positives = 87/185 (47%), Gaps = 6/185 (3%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSH--MHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTF 369
L ++ +LY + +SH KL +PGP P+P GN L+ + + + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKG----FCMFDMECHKKY 68
Query: 370 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 543
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 544 SHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLET 717
R +++PTF LK V I Q + +V L+ +E GK + D ++D++ T
Sbjct: 128 RLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITST 187
Query: 718 AMGIS 732
+ G++
Sbjct: 188 SFGVN 192
>DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 60.5 bits (140), Expect = 8e-09
Identities = 45/185 (24%), Positives = 87/185 (47%), Gaps = 6/185 (3%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSH--MHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTF 369
L ++ +LY + +SH KL +PGP P+P GN L+ + + + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKG----FCMFDMECHKKY 68
Query: 370 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 543
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 544 SHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLET 717
R +++PTF LK V I Q + +V L+ +E GK + D ++D++ T
Sbjct: 128 RLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITST 187
Query: 718 AMGIS 732
+ G++
Sbjct: 188 SFGVN 192
>BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfamily
IIIA, polypeptide 4 protein.
Length = 503
Score = 60.5 bits (140), Expect = 8e-09
Identities = 45/185 (24%), Positives = 87/185 (47%), Gaps = 6/185 (3%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSH--MHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTF 369
L ++ +LY + +SH KL +PGP P+P GN L+ + + + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKG----FCMFDMECHKKY 68
Query: 370 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 543
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 544 SHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLET 717
R +++PTF LK V I Q + +V L+ +E GK + D ++D++ T
Sbjct: 128 RLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITST 187
Query: 718 AMGIS 732
+ G++
Sbjct: 188 SFGVN 192
>BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 60.5 bits (140), Expect = 8e-09
Identities = 45/185 (24%), Positives = 87/185 (47%), Gaps = 6/185 (3%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSH--MHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTF 369
L ++ +LY + +SH KL +PGP P+P GN L+ + + + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKG----FCMFDMECHKKY 68
Query: 370 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 543
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 544 SHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLET 717
R +++PTF LK V I Q + +V L+ +E GK + D ++D++ T
Sbjct: 128 RLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITST 187
Query: 718 AMGIS 732
+ G++
Sbjct: 188 SFGVN 192
>AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450
polypeptide 4 protein.
Length = 503
Score = 60.5 bits (140), Expect = 8e-09
Identities = 45/185 (24%), Positives = 87/185 (47%), Gaps = 6/185 (3%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSH--MHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTF 369
L ++ +LY + +SH KL +PGP P+P GN L+ + + + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKG----FCMFDMECHKKY 68
Query: 370 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 543
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 544 SHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLET 717
R +++PTF LK V I Q + +V L+ +E GK + D ++D++ T
Sbjct: 128 RLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITST 187
Query: 718 AMGIS 732
+ G++
Sbjct: 188 SFGVN 192
>AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4
protein.
Length = 503
Score = 60.5 bits (140), Expect = 8e-09
Identities = 45/185 (24%), Positives = 87/185 (47%), Gaps = 6/185 (3%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSH--MHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTF 369
L ++ +LY + +SH KL +PGP P+P GN L+ + + + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKG----FCMFDMECHKKY 68
Query: 370 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 543
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 544 SHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLET 717
R +++PTF LK V I Q + +V L+ +E GK + D ++D++ T
Sbjct: 128 RLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITST 187
Query: 718 AMGIS 732
+ G++
Sbjct: 188 SFGVN 192
>AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4
protein.
Length = 503
Score = 60.5 bits (140), Expect = 8e-09
Identities = 45/185 (24%), Positives = 87/185 (47%), Gaps = 6/185 (3%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSH--MHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTF 369
L ++ +LY + +SH KL +PGP P+P GN L+ + + + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKG----FCMFDMECHKKY 68
Query: 370 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 543
G V + G + ++ + D D I+ +L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWK 127
Query: 544 SHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLET 717
R +++PTF LK V I Q + +V L+ +E GK + D ++D++ T
Sbjct: 128 RLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITST 187
Query: 718 AMGIS 732
+ G++
Sbjct: 188 SFGVN 192
>M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver
glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
complete cds. ).
Length = 504
Score = 58.8 bits (136), Expect = 2e-08
Identities = 44/185 (23%), Positives = 87/185 (47%), Gaps = 6/185 (3%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSH--MHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTF 369
L ++ +LY + +SH KL +PGP P+P GN L+ + + + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKG----FCMFDMECHKKY 68
Query: 370 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 543
G V + G + ++ + D D I+++L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKLVLVKECY-SVFTNREPFGPVGFMKSAISIAEDEEWK 127
Query: 544 SHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLET 717
R +++PTF LK V I Q + +V L+ E GK + D ++D++ +
Sbjct: 128 RLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRRERETGKPVTLKDVFGAYSMDVITSS 187
Query: 718 AMGIS 732
+ G++
Sbjct: 188 SFGVN 192
>D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein.
Length = 504
Score = 58.8 bits (136), Expect = 2e-08
Identities = 44/185 (23%), Positives = 87/185 (47%), Gaps = 6/185 (3%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSH--MHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTF 369
L ++ +LY + +SH KL +PGP P+P GN L+ + + + +
Sbjct: 15 LAVSLVLLYLYGTHSHGLFKKLG--IPGPTPLPFLGNILSYHKG----FCMFDMECHKKY 68
Query: 370 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 543
G V + G + ++ + D D I+++L + T + F P ++ + I+ +W+
Sbjct: 69 GKVWGFYDGQQPVLAITDPDMIKLVLVKECY-SVFTNREPFGPVGFMKSAISIAEDEEWK 127
Query: 544 SHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLET 717
R +++PTF LK V I Q + +V L+ E GK + D ++D++ +
Sbjct: 128 RLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRRERETGKPVTLKDVFGAYSMDVITSS 187
Query: 718 AMGIS 732
+ G++
Sbjct: 188 SFGVN 192
>AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43.1
protein.
Length = 503
Score = 58.0 bits (134), Expect = 4e-08
Identities = 45/185 (24%), Positives = 86/185 (46%), Gaps = 6/185 (3%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSHMHKLAELL--PGPAPIPIFGNALTLMRKSPHELVNLALGYAQTF 369
+ T++ +LY + +H HKL + L PGP P+P G L +R L N + +
Sbjct: 15 VATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLRG----LWNFDRECNEKY 68
Query: 370 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 543
G + ++ G + ++ + D D I+ +L + T P +L L + +W+
Sbjct: 69 GEMWGLYEGQQPMLVIMDPDMIKTVLVKECY-SVFTNQMPLGPMGFLKSALSFAEDEEWK 127
Query: 544 SHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV--GKTFDVHDYMSGTTVDILLET 717
R +++P F K V I +Q + +V L+ E K+ ++ D+ T+D++ T
Sbjct: 128 RIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGT 187
Query: 718 AMGIS 732
G++
Sbjct: 188 LFGVN 192
>AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43.3
protein.
Length = 503
Score = 58.0 bits (134), Expect = 4e-08
Identities = 45/185 (24%), Positives = 86/185 (46%), Gaps = 6/185 (3%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSHMHKLAELL--PGPAPIPIFGNALTLMRKSPHELVNLALGYAQTF 369
+ T++ +LY + +H HKL + L PGP P+P G L +R L N + +
Sbjct: 15 VATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLRG----LWNFDRECNEKY 68
Query: 370 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 543
G + ++ G + ++ + D D I+ +L + T P +L L + +W+
Sbjct: 69 GEMWGLYEGQQPMLVIMDPDMIKTVLVKECY-SVFTNQMPLGPMGFLKSALSFAEDEEWK 127
Query: 544 SHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV--GKTFDVHDYMSGTTVDILLET 717
R +++P F K V I +Q + +V L+ E K+ ++ D+ T+D++ T
Sbjct: 128 RIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGT 187
Query: 718 AMGIS 732
G++
Sbjct: 188 LFGVN 192
>AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 58.0 bits (134), Expect = 4e-08
Identities = 45/185 (24%), Positives = 86/185 (46%), Gaps = 6/185 (3%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSHMHKLAELL--PGPAPIPIFGNALTLMRKSPHELVNLALGYAQTF 369
+ T++ +LY + +H HKL + L PGP P+P G L +R L N + +
Sbjct: 15 VATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLRG----LWNFDRECNEKY 68
Query: 370 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 543
G + ++ G + ++ + D D I+ +L + T P +L L + +W+
Sbjct: 69 GEMWGLYEGQQPMLVIMDPDMIKTVLVKECY-SVFTNQMPLGPMGFLKSALSFAEDEEWK 127
Query: 544 SHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV--GKTFDVHDYMSGTTVDILLET 717
R +++P F K V I +Q + +V L+ E K+ ++ D+ T+D++ T
Sbjct: 128 RIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGT 187
Query: 718 AMGIS 732
G++
Sbjct: 188 LFGVN 192
>AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43
protein.
Length = 503
Score = 58.0 bits (134), Expect = 4e-08
Identities = 45/185 (24%), Positives = 86/185 (46%), Gaps = 6/185 (3%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSHMHKLAELL--PGPAPIPIFGNALTLMRKSPHELVNLALGYAQTF 369
+ T++ +LY + +H HKL + L PGP P+P G L +R L N + +
Sbjct: 15 VATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLRG----LWNFDRECNEKY 68
Query: 370 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 543
G + ++ G + ++ + D D I+ +L + T P +L L + +W+
Sbjct: 69 GEMWGLYEGQQPMLVIMDPDMIKTVLVKECY-SVFTNQMPLGPMGFLKSALSFAEDEEWK 127
Query: 544 SHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV--GKTFDVHDYMSGTTVDILLET 717
R +++P F K V I +Q + +V L+ E K+ ++ D+ T+D++ T
Sbjct: 128 RIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGT 187
Query: 718 AMGIS 732
G++
Sbjct: 188 LFGVN 192
>AF280111-1|AAG33012.1| 250|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 250
Score = 58.0 bits (134), Expect = 4e-08
Identities = 45/185 (24%), Positives = 86/185 (46%), Gaps = 6/185 (3%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSHMHKLAELL--PGPAPIPIFGNALTLMRKSPHELVNLALGYAQTF 369
+ T++ +LY + +H HKL + L PGP P+P G L +R L N + +
Sbjct: 15 VATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLRG----LWNFDRECNEKY 68
Query: 370 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 543
G + ++ G + ++ + D D I+ +L + T P +L L + +W+
Sbjct: 69 GEMWGLYEGQQPMLVIMDPDMIKTVLVKECY-SVFTNQMPLGPMGFLKSALSFAEDEEWK 127
Query: 544 SHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV--GKTFDVHDYMSGTTVDILLET 717
R +++P F K V I +Q + +V L+ E K+ ++ D+ T+D++ T
Sbjct: 128 RIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGT 187
Query: 718 AMGIS 732
G++
Sbjct: 188 LFGVN 192
>AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 420
Score = 58.0 bits (134), Expect = 4e-08
Identities = 45/185 (24%), Positives = 86/185 (46%), Gaps = 6/185 (3%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSHMHKLAELL--PGPAPIPIFGNALTLMRKSPHELVNLALGYAQTF 369
+ T++ +LY + +H HKL + L PGP P+P G L +R L N + +
Sbjct: 15 VATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLRG----LWNFDRECNEKY 68
Query: 370 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 543
G + ++ G + ++ + D D I+ +L + T P +L L + +W+
Sbjct: 69 GEMWGLYEGQQPMLVIMDPDMIKTVLVKECY-SVFTNQMPLGPMGFLKSALSFAEDEEWK 127
Query: 544 SHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV--GKTFDVHDYMSGTTVDILLET 717
R +++P F K V I +Q + +V L+ E K+ ++ D+ T+D++ T
Sbjct: 128 RIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGT 187
Query: 718 AMGIS 732
G++
Sbjct: 188 LFGVN 192
>AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 504
Score = 58.0 bits (134), Expect = 4e-08
Identities = 45/185 (24%), Positives = 86/185 (46%), Gaps = 6/185 (3%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSHMHKLAELL--PGPAPIPIFGNALTLMRKSPHELVNLALGYAQTF 369
+ T++ +LY + +H HKL + L PGP P+P G L +R L N + +
Sbjct: 15 VATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLRG----LWNFDRECNEKY 68
Query: 370 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 543
G + ++ G + ++ + D D I+ +L + T P +L L + +W+
Sbjct: 69 GEMWGLYEGQQPMLVIMDPDMIKTVLVKECY-SVFTNQMPLGPMGFLKSALSFAEDEEWK 127
Query: 544 SHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV--GKTFDVHDYMSGTTVDILLET 717
R +++P F K V I +Q + +V L+ E K+ ++ D+ T+D++ T
Sbjct: 128 RIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGT 187
Query: 718 AMGIS 732
G++
Sbjct: 188 LFGVN 192
>AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 58.0 bits (134), Expect = 4e-08
Identities = 45/185 (24%), Positives = 86/185 (46%), Gaps = 6/185 (3%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSHMHKLAELL--PGPAPIPIFGNALTLMRKSPHELVNLALGYAQTF 369
+ T++ +LY + +H HKL + L PGP P+P G L +R L N + +
Sbjct: 15 VATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLRG----LWNFDRECNEKY 68
Query: 370 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 543
G + ++ G + ++ + D D I+ +L + T P +L L + +W+
Sbjct: 69 GEMWGLYEGQQPMLVIMDPDMIKTVLVKECY-SVFTNQMPLGPMGFLKSALSFAEDEEWK 127
Query: 544 SHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV--GKTFDVHDYMSGTTVDILLET 717
R +++P F K V I +Q + +V L+ E K+ ++ D+ T+D++ T
Sbjct: 128 RIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGT 187
Query: 718 AMGIS 732
G++
Sbjct: 188 LFGVN 192
>AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein.
Length = 504
Score = 58.0 bits (134), Expect = 4e-08
Identities = 45/185 (24%), Positives = 86/185 (46%), Gaps = 6/185 (3%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSHMHKLAELL--PGPAPIPIFGNALTLMRKSPHELVNLALGYAQTF 369
+ T++ +LY + +H HKL + L PGP P+P G L +R L N + +
Sbjct: 15 VATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLRG----LWNFDRECNEKY 68
Query: 370 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 543
G + ++ G + ++ + D D I+ +L + T P +L L + +W+
Sbjct: 69 GEMWGLYEGQQPMLVIMDPDMIKTVLVKECY-SVFTNQMPLGPMGFLKSALSFAEDEEWK 127
Query: 544 SHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV--GKTFDVHDYMSGTTVDILLET 717
R +++P F K V I +Q + +V L+ E K+ ++ D+ T+D++ T
Sbjct: 128 RIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGT 187
Query: 718 AMGIS 732
G++
Sbjct: 188 LFGVN 192
>AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein.
Length = 503
Score = 58.0 bits (134), Expect = 4e-08
Identities = 45/185 (24%), Positives = 86/185 (46%), Gaps = 6/185 (3%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSHMHKLAELL--PGPAPIPIFGNALTLMRKSPHELVNLALGYAQTF 369
+ T++ +LY + +H HKL + L PGP P+P G L +R L N + +
Sbjct: 15 VATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLRG----LWNFDRECNEKY 68
Query: 370 GNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWR 543
G + ++ G + ++ + D D I+ +L + T P +L L + +W+
Sbjct: 69 GEMWGLYEGQQPMLVIMDPDMIKTVLVKECY-SVFTNQMPLGPMGFLKSALSFAEDEEWK 127
Query: 544 SHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEV--GKTFDVHDYMSGTTVDILLET 717
R +++P F K V I +Q + +V L+ E K+ ++ D+ T+D++ T
Sbjct: 128 RIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGT 187
Query: 718 AMGIS 732
G++
Sbjct: 188 LFGVN 192
>X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mRNA
for P-450 IIA4 protein. ).
Length = 494
Score = 56.0 bits (129), Expect = 2e-07
Identities = 52/206 (25%), Positives = 87/206 (42%), Gaps = 6/206 (2%)
Frame = +1
Query: 166 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNL 345
S ++ LL T + ++ WQQ KL PGP P+P GN L L + ++ N
Sbjct: 4 SGMLLVALLVCLTVMVLMSVWQQRKSKGKLP---PGPTPLPFIGNYLQL---NTEQMYNS 57
Query: 346 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 516
+ ++ +G V + LG + +V L D + E +++ E F W+ G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATF-DWVFKGYGV 116
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
+ S+G + + R+ F I L+ F G+ + E+++ E G D H G
Sbjct: 117 VFSNGERAKQLRR-----FSIATLRDF-GV---GKRGIEERIQEEAGFLIDAHRGTGGAN 167
Query: 697 VD---ILLETAMGISRKTQDESXFDY 765
+D L T + FDY
Sbjct: 168 IDPTFFLSRTVSNVISSIVFGDRFDY 193
>D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa
protein.
Length = 503
Score = 56.0 bits (129), Expect = 2e-07
Identities = 46/194 (23%), Positives = 89/194 (45%), Gaps = 4/194 (2%)
Frame = +1
Query: 163 NSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVN 342
N V + LL ++ + LY + + KL +PGP P+P GNAL+ + +
Sbjct: 6 NLAVETWLLLAVSLILLYLYGTRTHGLFKKLG--IPGPTPLPFLGNALSFRKGYWTFDME 63
Query: 343 LALGYAQTFGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGL 516
Y + +G ++ + ++ + D D I+ +L + T + F P ++ +
Sbjct: 64 CYKKYRKVWG----IYDCQQPMLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKNAI 118
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSG 690
I+ +W+ R +++PTF LK V I Q + +V L+ +E GK +
Sbjct: 119 SIAEDEEWKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGA 178
Query: 691 TTVDILLETAMGIS 732
++D++ T+ G+S
Sbjct: 179 YSMDVITSTSFGVS 192
>BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 56.0 bits (129), Expect = 2e-07
Identities = 52/206 (25%), Positives = 87/206 (42%), Gaps = 6/206 (2%)
Frame = +1
Query: 166 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNL 345
S ++ LL T + ++ WQQ KL PGP P+P GN L L + ++ N
Sbjct: 4 SGMLLVALLVCLTVMVLMSVWQQRKSKGKLP---PGPTPLPFIGNYLQL---NTEQMYNS 57
Query: 346 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 516
+ ++ +G V + LG + +V L D + E +++ E F W+ G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATF-DWVFKGYGV 116
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
+ S+G + + R+ F I L+ F G+ + E+++ E G D H G
Sbjct: 117 VFSNGERAKQLRR-----FSIATLRDF-GV---GKRGIEERIQEEAGFLIDAHRGTGGAN 167
Query: 697 VD---ILLETAMGISRKTQDESXFDY 765
+D L T + FDY
Sbjct: 168 IDPTFFLSRTVSNVISSIVFGDRFDY 193
>BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 7 protein.
Length = 503
Score = 56.0 bits (129), Expect = 2e-07
Identities = 46/194 (23%), Positives = 89/194 (45%), Gaps = 4/194 (2%)
Frame = +1
Query: 163 NSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVN 342
N V + LL ++ + LY + + KL +PGP P+P GNAL+ + +
Sbjct: 6 NLAVETWLLLAVSLILLYLYGTRTHGLFKKLG--IPGPTPLPFLGNALSFRKGYWTFDME 63
Query: 343 LALGYAQTFGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGL 516
Y + +G ++ + ++ + D D I+ +L + T + F P ++ +
Sbjct: 64 CYKKYRKVWG----IYDCQQPMLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKNAI 118
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSG 690
I+ +W+ R +++PTF LK V I Q + +V L+ +E GK +
Sbjct: 119 SIAEDEEWKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGA 178
Query: 691 TTVDILLETAMGIS 732
++D++ T+ G+S
Sbjct: 179 YSMDVITSTSFGVS 192
>AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant
3A7 protein.
Length = 535
Score = 56.0 bits (129), Expect = 2e-07
Identities = 46/194 (23%), Positives = 89/194 (45%), Gaps = 4/194 (2%)
Frame = +1
Query: 163 NSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVN 342
N V + LL ++ + LY + + KL +PGP P+P GNAL+ + +
Sbjct: 6 NLAVETWLLLAVSLILLYLYGTRTHGLFKKLG--IPGPTPLPFLGNALSFRKGYWTFDME 63
Query: 343 LALGYAQTFGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGL 516
Y + +G ++ + ++ + D D I+ +L + T + F P ++ +
Sbjct: 64 CYKKYRKVWG----IYDCQQPMLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKNAI 118
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSG 690
I+ +W+ R +++PTF LK V I Q + +V L+ +E GK +
Sbjct: 119 SIAEDEEWKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGA 178
Query: 691 TTVDILLETAMGIS 732
++D++ T+ G+S
Sbjct: 179 YSMDVITSTSFGVS 192
>AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450
polypeptide 7 protein.
Length = 503
Score = 56.0 bits (129), Expect = 2e-07
Identities = 46/194 (23%), Positives = 89/194 (45%), Gaps = 4/194 (2%)
Frame = +1
Query: 163 NSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVN 342
N V + LL ++ + LY + + KL +PGP P+P GNAL+ + +
Sbjct: 6 NLAVETWLLLAVSLILLYLYGTRTHGLFKKLG--IPGPTPLPFLGNALSFRKGYWTFDME 63
Query: 343 LALGYAQTFGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGL 516
Y + +G ++ + ++ + D D I+ +L + T + F P ++ +
Sbjct: 64 CYKKYRKVWG----IYDCQQPMLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKNAI 118
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSG 690
I+ +W+ R +++PTF LK V I Q + +V L+ +E GK +
Sbjct: 119 SIAEDEEWKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGA 178
Query: 691 TTVDILLETAMGIS 732
++D++ T+ G+S
Sbjct: 179 YSMDVITSTSFGVS 192
>J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3
protein.
Length = 502
Score = 52.8 bits (121), Expect = 2e-06
Identities = 42/194 (21%), Positives = 86/194 (44%), Gaps = 4/194 (2%)
Frame = +1
Query: 163 NSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVN 342
N V + LL ++ + LY + + +L +PGP P+P+ GN L+ + L
Sbjct: 6 NLAVETWLLLAVSLVLLYLYGTRTHGLFKRLG--IPGPTPLPLLGNVLSYRQG----LWK 59
Query: 343 LALGYAQTFGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGL 516
+ +G + + G ++ + D D I +L + T + P ++ +
Sbjct: 60 FDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECY-SVFTNRRSLGPVGFMKSAI 118
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSG 690
++ +W+ R +++PTF LK I Q + +V L+ +E GK + D
Sbjct: 119 SLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGA 178
Query: 691 TTVDILLETAMGIS 732
++D++ T+ G++
Sbjct: 179 YSMDVITGTSFGVN 192
>DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P450,
family 3, subfamily A, polypeptide 5 protein.
Length = 347
Score = 52.8 bits (121), Expect = 2e-06
Identities = 42/194 (21%), Positives = 86/194 (44%), Gaps = 4/194 (2%)
Frame = +1
Query: 163 NSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVN 342
N V + LL ++ + LY + + +L +PGP P+P+ GN L+ + L
Sbjct: 6 NLAVETWLLLAVSLVLLYLYGTRTHGLFKRLG--IPGPTPLPLLGNVLSYRQG----LWK 59
Query: 343 LALGYAQTFGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGL 516
+ +G + + G ++ + D D I +L + T + P ++ +
Sbjct: 60 FDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECY-SVFTNRRSLGPVGFMKSAI 118
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSG 690
++ +W+ R +++PTF LK I Q + +V L+ +E GK + D
Sbjct: 119 SLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGA 178
Query: 691 TTVDILLETAMGIS 732
++D++ T+ G++
Sbjct: 179 YSMDVITGTSFGVN 192
>BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 protein.
Length = 502
Score = 52.8 bits (121), Expect = 2e-06
Identities = 42/194 (21%), Positives = 86/194 (44%), Gaps = 4/194 (2%)
Frame = +1
Query: 163 NSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVN 342
N V + LL ++ + LY + + +L +PGP P+P+ GN L+ + L
Sbjct: 6 NLAVETWLLLAVSLVLLYLYGTRTHGLFKRLG--IPGPTPLPLLGNVLSYRQG----LWK 59
Query: 343 LALGYAQTFGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGL 516
+ +G + + G ++ + D D I +L + T + P ++ +
Sbjct: 60 FDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECY-SVFTNRRSLGPVGFMKSAI 118
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSG 690
++ +W+ R +++PTF LK I Q + +V L+ +E GK + D
Sbjct: 119 SLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGA 178
Query: 691 TTVDILLETAMGIS 732
++D++ T+ G++
Sbjct: 179 YSMDVITGTSFGVN 192
>AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein.
Length = 502
Score = 52.8 bits (121), Expect = 2e-06
Identities = 42/194 (21%), Positives = 86/194 (44%), Gaps = 4/194 (2%)
Frame = +1
Query: 163 NSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVN 342
N V + LL ++ + LY + + +L +PGP P+P+ GN L+ + L
Sbjct: 6 NLAVETWLLLAVSLVLLYLYGTRTHGLFKRLG--IPGPTPLPLLGNVLSYRQG----LWK 59
Query: 343 LALGYAQTFGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGL 516
+ +G + + G ++ + D D I +L + T + P ++ +
Sbjct: 60 FDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECY-SVFTNRRSLGPVGFMKSAI 118
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSG 690
++ +W+ R +++PTF LK I Q + +V L+ +E GK + D
Sbjct: 119 SLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGA 178
Query: 691 TTVDILLETAMGIS 732
++D++ T+ G++
Sbjct: 179 YSMDVITGTSFGVN 192
>M29873-1|AAA52143.1| 377|Homo sapiens CYP2B protein.
Length = 377
Score = 52.4 bits (120), Expect = 2e-06
Identities = 45/189 (23%), Positives = 82/189 (43%), Gaps = 4/189 (2%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGN 375
LT + +L + NSH L PGP P+P+ GN L + R+ L+ L + + +G+
Sbjct: 12 LTGLLLLLVQRHPNSH----GTLPPGPRPLPLLGNLLQMDRRG---LLKSFLRFREKYGD 64
Query: 376 VVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKP-WLGEGLLISSGPKWRSH 549
V V LG + +V L + I E ++++ + P + G G+L ++G +W+
Sbjct: 65 VFTVHLGPRPVVMLCGVEAIREALVDNAEAFSGRGKIVIMDPVYQGYGMLFANGNRWKVL 124
Query: 550 RKMIAPTFHINIL--KSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAM 723
R+ T + +S + ++E+L+ G D T +I+
Sbjct: 125 RRFSVTTMRDFGMGKRSVEERIQDEAQCLIEELRKSKGALVDPTFLFHSITANIICSIIF 184
Query: 724 GISRKTQDE 750
G QD+
Sbjct: 185 GKRFHYQDQ 193
>BC041174-1|AAH41174.1| 377|Homo sapiens CYP2B7P1 protein protein.
Length = 377
Score = 52.4 bits (120), Expect = 2e-06
Identities = 45/189 (23%), Positives = 82/189 (43%), Gaps = 4/189 (2%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGN 375
LT + +L + NSH L PGP P+P+ GN L + R+ L+ L + + +G+
Sbjct: 12 LTGLLLLLVQRHPNSH----GTLPPGPRPLPLLGNLLQMDRRG---LLKSFLRFREKYGD 64
Query: 376 VVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKP-WLGEGLLISSGPKWRSH 549
V V LG + +V L + I E ++++ + P + G G+L ++G +W+
Sbjct: 65 VFTVHLGPRPVVMLCGVEAIREALVDNAEAFSGRGKIVIMDPVYQGYGMLFANGNRWKVL 124
Query: 550 RKMIAPTFHINIL--KSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAM 723
R+ T + +S + ++E+L+ G D T +I+
Sbjct: 125 RRFSVTTMRDFGMGKRSVEERIQDEAQCLIEELRKSKGALVDPTFLFHSITANIICSIIF 184
Query: 724 GISRKTQDE 750
G QD+
Sbjct: 185 GKRFHYQDQ 193
>AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 variant protein.
Length = 502
Score = 52.4 bits (120), Expect = 2e-06
Identities = 42/194 (21%), Positives = 86/194 (44%), Gaps = 4/194 (2%)
Frame = +1
Query: 163 NSRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVN 342
N V + LL ++ + LY + + +L +PGP P+P+ GN L+ + L
Sbjct: 6 NLAVETWLLLAVSLVLLYLYGTRTHGLFKRLG--IPGPTPLPLLGNVLSYRQG----LWK 59
Query: 343 LALGYAQTFGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGL 516
+ +G + + G ++ + D D I +L + T + P ++ +
Sbjct: 60 FDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECY-SVFTNRRSLGPVGFMKSAI 118
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSG 690
++ +W+ R +++PTF LK I Q + +V L+ +E GK + D
Sbjct: 119 SLAEDEEWKRIRPLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGA 178
Query: 691 TTVDILLETAMGIS 732
++D++ T+ G++
Sbjct: 179 YSMDVITGTSFGVN 192
>X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for
cytochrome P-450IIA. ).
Length = 489
Score = 51.6 bits (118), Expect = 4e-06
Identities = 50/204 (24%), Positives = 86/204 (42%), Gaps = 6/204 (2%)
Frame = +1
Query: 172 VIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLAL 351
++ LL T + ++ WQQ + KL PGP P+P GN L L + ++ N +
Sbjct: 1 MLLVALLVCLTVMVLMSVWQQRKNKGKLP---PGPTPLPFIGNYLQL---NTEQMYNSLM 54
Query: 352 GYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGLLI 522
++ +G V + LG + +V L D + E +++ E F W+ G G++
Sbjct: 55 KISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATF-DWVFKGYGVVF 113
Query: 523 SSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVD 702
S+G + + R+ F I L+ F G+ + E+++ E G D G +D
Sbjct: 114 SNGERAKQLRR-----FSIATLRDF-GV---GKRGIEERIQEEAGFLIDALRGTGGANID 164
Query: 703 ---ILLETAMGISRKTQDESXFDY 765
L T + FDY
Sbjct: 165 PTFFLSRTVSNVISSIVFGDRFDY 188
>U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 51.6 bits (118), Expect = 4e-06
Identities = 46/192 (23%), Positives = 84/192 (43%), Gaps = 5/192 (2%)
Frame = +1
Query: 166 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNL 345
S ++ LL T + ++ WQQ KL PGP P+P GN L L + ++ N
Sbjct: 4 SGMLLVALLACLTVMVLMSVWQQRKSKGKLP---PGPTPLPFIGNYLQL---NTEQMYNS 57
Query: 346 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 516
+ ++ +G V + LG + +V L D + E +++ E F W+ G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATF-DWVFKGYGV 116
Query: 517 LISSGPKWRS-HRKMIAPTFHINILKSFV-GIFNQNSNNVVEKLKSEVGKTFDVHDYMSG 690
+ S+G + + R IA + K + + S ++E ++S G D ++S
Sbjct: 117 VFSNGERAKQLLRFAIATLRDFGVGKRGIEERIQEESGFLIEAIRSTHGANIDPTFFLSR 176
Query: 691 TTVDILLETAMG 726
T +++ G
Sbjct: 177 TVSNVISSIVFG 188
>M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 51.6 bits (118), Expect = 4e-06
Identities = 51/206 (24%), Positives = 86/206 (41%), Gaps = 6/206 (2%)
Frame = +1
Query: 166 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNL 345
S ++ LL T + ++ WQQ KL PGP P+P GN L L + ++ N
Sbjct: 4 SGMLLVALLVCLTVMVLMSVWQQRKSKGKLP---PGPTPLPFIGNYLQL---NTEQMYNS 57
Query: 346 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 516
+ ++ +G V + LG + +V L D + E +++ E F W+ G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATF-DWVFKGYGV 116
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
+ S+G + + R+ F I L+ F G+ + E+++ E G D G
Sbjct: 117 VFSNGERAKQLRR-----FSIATLRDF-GV---GKRGIEERIQEEAGFLIDALRGTGGAN 167
Query: 697 VD---ILLETAMGISRKTQDESXFDY 765
+D L T + FDY
Sbjct: 168 IDPTFFLSRTVSNVISSIVFGDRFDY 193
>M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein.
Length = 491
Score = 51.6 bits (118), Expect = 4e-06
Identities = 43/189 (22%), Positives = 82/189 (43%), Gaps = 4/189 (2%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGN 375
LT + +L + N+H L PGP P+P+ GN L + R+ L+ L + + +G+
Sbjct: 12 LTGLLLLLVQRHPNTH----DRLPPGPRPLPLLGNLLQMDRRG---LLKSFLRFREKYGD 64
Query: 376 VVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL-GEGLLISSGPKWRSH 549
V V LG + +V L + I E +++ + P+ G G++ ++G +W+
Sbjct: 65 VFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVL 124
Query: 550 RKMIAPTFHINIL--KSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAM 723
R+ T + +S + + ++E+L+ G D T +I+
Sbjct: 125 RRFSVTTMRDFGMGKRSVEERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVF 184
Query: 724 GISRKTQDE 750
G QD+
Sbjct: 185 GKRFHYQDQ 193
>DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 51.6 bits (118), Expect = 4e-06
Identities = 43/189 (22%), Positives = 82/189 (43%), Gaps = 4/189 (2%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGN 375
LT + +L + N+H L PGP P+P+ GN L + R+ L+ L + + +G+
Sbjct: 12 LTGLLLLLVQRHPNTH----DRLPPGPRPLPLLGNLLQMDRRG---LLKSFLRFREKYGD 64
Query: 376 VVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL-GEGLLISSGPKWRSH 549
V V LG + +V L + I E +++ + P+ G G++ ++G +W+
Sbjct: 65 VFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVL 124
Query: 550 RKMIAPTFHINIL--KSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAM 723
R+ T + +S + + ++E+L+ G D T +I+
Sbjct: 125 RRFSVTTMRDFGMGKRSVEERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVF 184
Query: 724 GISRKTQDE 750
G QD+
Sbjct: 185 GKRFHYQDQ 193
>BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 51.6 bits (118), Expect = 4e-06
Identities = 51/206 (24%), Positives = 86/206 (41%), Gaps = 6/206 (2%)
Frame = +1
Query: 166 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNL 345
S ++ LL T + ++ WQQ KL PGP P+P GN L L + ++ N
Sbjct: 4 SGMLLVALLVCLTVMVLMSVWQQRKSKGKLP---PGPTPLPFIGNYLQL---NTEQMYNS 57
Query: 346 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 516
+ ++ +G V + LG + +V L D + E +++ E F W+ G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATF-DWVFKGYGV 116
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
+ S+G + + R+ F I L+ F G+ + E+++ E G D G
Sbjct: 117 VFSNGERAKQLRR-----FSIATLRDF-GV---GKRGIEERIQEEAGFLIDALRGTGGAN 167
Query: 697 VD---ILLETAMGISRKTQDESXFDY 765
+D L T + FDY
Sbjct: 168 IDPTFFLSRTVSNVISSIVFGDRFDY 193
>BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 51.6 bits (118), Expect = 4e-06
Identities = 51/206 (24%), Positives = 86/206 (41%), Gaps = 6/206 (2%)
Frame = +1
Query: 166 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNL 345
S ++ LL T + ++ WQQ KL PGP P+P GN L L + ++ N
Sbjct: 4 SGMLLVALLVCLTVMVLMSVWQQRKSKGKLP---PGPTPLPFIGNYLQL---NTEQMYNS 57
Query: 346 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 516
+ ++ +G V + LG + +V L D + E +++ E F W+ G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATF-DWVFKGYGV 116
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
+ S+G + + R+ F I L+ F G+ + E+++ E G D G
Sbjct: 117 VFSNGERAKQLRR-----FSIATLRDF-GV---GKRGIEERIQEEAGFLIDALRGTGGAN 167
Query: 697 VD---ILLETAMGISRKTQDESXFDY 765
+D L T + FDY
Sbjct: 168 IDPTFFLSRTVSNVISSIVFGDRFDY 193
>BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 51.6 bits (118), Expect = 4e-06
Identities = 51/206 (24%), Positives = 86/206 (41%), Gaps = 6/206 (2%)
Frame = +1
Query: 166 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNL 345
S ++ LL T + ++ WQQ KL PGP P+P GN L L + ++ N
Sbjct: 4 SGMLLVALLVCLTVMVLMSVWQQRKSKGKLP---PGPTPLPFIGNYLQL---NTEQMYNS 57
Query: 346 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 516
+ ++ +G V + LG + +V L D + E +++ E F W+ G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATF-DWVFKGYGV 116
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
+ S+G + + R+ F I L+ F G+ + E+++ E G D G
Sbjct: 117 VFSNGERAKQLRR-----FSIATLRDF-GV---GKRGIEERIQEEAGFLIDALRGTGGAN 167
Query: 697 VD---ILLETAMGISRKTQDESXFDY 765
+D L T + FDY
Sbjct: 168 IDPTFFLSRTVSNVISSIVFGDRFDY 193
>BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 51.6 bits (118), Expect = 4e-06
Identities = 43/189 (22%), Positives = 82/189 (43%), Gaps = 4/189 (2%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGN 375
LT + +L + N+H L PGP P+P+ GN L + R+ L+ L + + +G+
Sbjct: 12 LTGLLLLLVQRHPNTH----DRLPPGPRPLPLLGNLLQMDRRG---LLKSFLRFREKYGD 64
Query: 376 VVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL-GEGLLISSGPKWRSH 549
V V LG + +V L + I E +++ + P+ G G++ ++G +W+
Sbjct: 65 VFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVL 124
Query: 550 RKMIAPTFHINIL--KSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAM 723
R+ T + +S + + ++E+L+ G D T +I+
Sbjct: 125 RRFSVTTMRDFGMGKRSVEERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVF 184
Query: 724 GISRKTQDE 750
G QD+
Sbjct: 185 GKRFHYQDQ 193
>AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6
protein.
Length = 491
Score = 51.6 bits (118), Expect = 4e-06
Identities = 45/189 (23%), Positives = 82/189 (43%), Gaps = 4/189 (2%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGN 375
LT + +L + N+H L PGP P+P+ GN L + R+ L+ L + + +G+
Sbjct: 12 LTGLLLLLVQRHPNTH----DRLPPGPRPLPLLGNLLQMDRRG---LLKSFLRFREKYGD 64
Query: 376 VVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL-GEGLLISSGPKWRSH 549
V V LG + +V L + I E +++ + P+ G G++ ++G +W+
Sbjct: 65 VFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVL 124
Query: 550 RKMIAPTFH-INILKSFVGIFNQ-NSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAM 723
R+ T + K V Q + ++E+L+ G D T +I+
Sbjct: 125 RRFSVTTMRDFGMGKRSVEERTQEEAQCLIEELRKSKGALMDATFLFHSITANIICSIVF 184
Query: 724 GISRKTQDE 750
G QD+
Sbjct: 185 GKRFHYQDQ 193
>AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6
protein.
Length = 494
Score = 51.6 bits (118), Expect = 4e-06
Identities = 51/206 (24%), Positives = 86/206 (41%), Gaps = 6/206 (2%)
Frame = +1
Query: 166 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNL 345
S ++ LL T + ++ WQQ KL PGP P+P GN L L + ++ N
Sbjct: 4 SGMLLVALLVCLTVMVLMSVWQQRKSKGKLP---PGPTPLPFIGNYLQL---NTEQMYNS 57
Query: 346 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 516
+ ++ +G V + LG + +V L D + E +++ E F W+ G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATF-DWVFKGYGV 116
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
+ S+G + + R+ F I L+ F G+ + E+++ E G D G
Sbjct: 117 VFSNGERAKQLRR-----FSIATLRDF-GV---GKRGIEERIQEEAGFLIDALRGTGGAN 167
Query: 697 VD---ILLETAMGISRKTQDESXFDY 765
+D L T + FDY
Sbjct: 168 IDPTFFLSRTVSNVISSIVFGDRFDY 193
>AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein.
Length = 491
Score = 51.6 bits (118), Expect = 4e-06
Identities = 43/189 (22%), Positives = 82/189 (43%), Gaps = 4/189 (2%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGN 375
LT + +L + N+H L PGP P+P+ GN L + R+ L+ L + + +G+
Sbjct: 12 LTGLLLLLVQRHPNTH----DRLPPGPRPLPLLGNLLQMDRRG---LLKSFLRFREKYGD 64
Query: 376 VVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL-GEGLLISSGPKWRSH 549
V V LG + +V L + I E +++ + P+ G G++ ++G +W+
Sbjct: 65 VFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVL 124
Query: 550 RKMIAPTFHINIL--KSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAM 723
R+ T + +S + + ++E+L+ G D T +I+
Sbjct: 125 RRFSVTTMRDFGMGKRSVEERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVF 184
Query: 724 GISRKTQDE 750
G QD+
Sbjct: 185 GKRFHYQDQ 193
>U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 51.2 bits (117), Expect = 5e-06
Identities = 50/221 (22%), Positives = 95/221 (42%), Gaps = 5/221 (2%)
Frame = +1
Query: 166 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNL 345
S ++ LL T + ++ WQQ KL PGP P+P GN L L + + +
Sbjct: 4 SGLLLVALLACLTVMVLMSVWQQRKSRGKLP---PGPTPLPFIGNYLQL---NTEHICDS 57
Query: 346 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 516
+ +++ +G V + LG + +V L D + E +++ E F+ W+ G G+
Sbjct: 58 IMKFSECYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFE-WVFKGYGV 116
Query: 517 LISSGPKWRS-HRKMIAPTFHINILKSFV-GIFNQNSNNVVEKLKSEVGKTFDVHDYMSG 690
S+G + + R IA + K + + S ++E ++S G D ++S
Sbjct: 117 AFSNGERAKQLLRFAIATLRDFGVGKRGIEERIQEESGFLIEAIRSTHGANIDPTFFLSR 176
Query: 691 TTVDILLETAMGISRKTQDESXFDYAMAVMKCAISSTKXTT 813
T +++ G R ++ F +++M T +T
Sbjct: 177 TVSNVISSIVFG-DRFDYEDKEFLSLLSMMLGIFQFTSTST 216
>U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 51.2 bits (117), Expect = 5e-06
Identities = 51/206 (24%), Positives = 85/206 (41%), Gaps = 6/206 (2%)
Frame = +1
Query: 166 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNL 345
S ++ LL T + ++ W+Q KL PGP P+P GN L L + ++ N
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSRGKLP---PGPTPLPFIGNYLQL---NTEQMYNS 57
Query: 346 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 516
+ ++ +G V + LG + +V L D + E +++ E F WL G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATF-DWLFKGYGV 116
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
S+G + + R+ F I L+ F G+ + E+++ E G D G
Sbjct: 117 AFSNGERAKQLRR-----FSIATLRGF-GV---GKRGIEERIQEEAGFLIDALRGTHGAN 167
Query: 697 VD---ILLETAMGISRKTQDESXFDY 765
+D L T + FDY
Sbjct: 168 IDPTFFLSRTVSNVISSIVFGDRFDY 193
>BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 51.2 bits (117), Expect = 5e-06
Identities = 43/189 (22%), Positives = 82/189 (43%), Gaps = 4/189 (2%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGN 375
LT + +L + N+H L PGP P+P+ GN L + R+ L+ L + + +G+
Sbjct: 12 LTGLLLLLVQRHPNTH----DRLPPGPRPLPLLGNLLQMDRRG---LLKSFLRFREKYGD 64
Query: 376 VVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL-GEGLLISSGPKWRSH 549
V V LG + +V L + I E +++ + P+ G G++ ++G +W+
Sbjct: 65 VFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVL 124
Query: 550 RKMIAPTFHINIL--KSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAM 723
R+ T + +S + + ++E+L+ G D T +I+
Sbjct: 125 RRFSVTTMRDFGMGKRSVEERIQEEAQCLIEELRKSKGALMDPTFLFHSITANIICSIVF 184
Query: 724 GISRKTQDE 750
G QD+
Sbjct: 185 GKRFHYQDQ 193
>AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13
variant 6 protein.
Length = 494
Score = 51.2 bits (117), Expect = 5e-06
Identities = 51/206 (24%), Positives = 85/206 (41%), Gaps = 6/206 (2%)
Frame = +1
Query: 166 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNL 345
S ++ LL T + ++ W+Q KL PGP P+P GN L L + ++ N
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSRGKLP---PGPTPLPFIGNYLQL---NTEQMYNS 57
Query: 346 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 516
+ ++ +G V + LG + +V L D + E +++ E F WL G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATF-DWLFKGYGV 116
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
S+G + + R+ F I L+ F G+ + E+++ E G D G
Sbjct: 117 AFSNGERAKQLRR-----FSIATLRGF-GV---GKRGIEERIQEEAGFLIDALRGTHGAN 167
Query: 697 VD---ILLETAMGISRKTQDESXFDY 765
+D L T + FDY
Sbjct: 168 IDPTFFLSRTVSNVISSIVFGDRFDY 193
>AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13
variant 3 protein.
Length = 494
Score = 51.2 bits (117), Expect = 5e-06
Identities = 51/206 (24%), Positives = 85/206 (41%), Gaps = 6/206 (2%)
Frame = +1
Query: 166 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNL 345
S ++ LL T + ++ W+Q KL PGP P+P GN L L + ++ N
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSRGKLP---PGPTPLPFIGNYLQL---NTEQMYNS 57
Query: 346 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 516
+ ++ +G V + LG + +V L D + E +++ E F WL G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATF-DWLFKGYGV 116
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
S+G + + R+ F I L+ F G+ + E+++ E G D G
Sbjct: 117 AFSNGERAKQLRR-----FSIATLRGF-GV---GKRGIEERIQEEAGFLIDALRGTHGAN 167
Query: 697 VD---ILLETAMGISRKTQDESXFDY 765
+D L T + FDY
Sbjct: 168 IDPTFFLSRTVSNVISSIVFGDRFDY 193
>AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13
variant 2 protein.
Length = 494
Score = 51.2 bits (117), Expect = 5e-06
Identities = 51/206 (24%), Positives = 85/206 (41%), Gaps = 6/206 (2%)
Frame = +1
Query: 166 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNL 345
S ++ LL T + ++ W+Q KL PGP P+P GN L L + ++ N
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSRGKLP---PGPTPLPFIGNYLQL---NTEQMYNS 57
Query: 346 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 516
+ ++ +G V + LG + +V L D + E +++ E F WL G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATF-DWLFKGYGV 116
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
S+G + + R+ F I L+ F G+ + E+++ E G D G
Sbjct: 117 AFSNGERAKQLRR-----FSIATLRGF-GV---GKRGIEERIQEEAGFLIDALRGTHGAN 167
Query: 697 VD---ILLETAMGISRKTQDESXFDY 765
+D L T + FDY
Sbjct: 168 IDPTFFLSRTVSNVISSIVFGDRFDY 193
>AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13
variant 1 protein.
Length = 494
Score = 51.2 bits (117), Expect = 5e-06
Identities = 51/206 (24%), Positives = 85/206 (41%), Gaps = 6/206 (2%)
Frame = +1
Query: 166 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNL 345
S ++ LL T + ++ W+Q KL PGP P+P GN L L + ++ N
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSRGKLP---PGPTPLPFIGNYLQL---NTEQMYNS 57
Query: 346 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 516
+ ++ +G V + LG + +V L D + E +++ E F WL G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATF-DWLFKGYGV 116
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
S+G + + R+ F I L+ F G+ + E+++ E G D G
Sbjct: 117 AFSNGERAKQLRR-----FSIATLRGF-GV---GKRGIEERIQEEAGFLIDALRGTHGAN 167
Query: 697 VD---ILLETAMGISRKTQDESXFDY 765
+D L T + FDY
Sbjct: 168 IDPTFFLSRTVSNVISSIVFGDRFDY 193
>AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13
protein.
Length = 494
Score = 51.2 bits (117), Expect = 5e-06
Identities = 51/206 (24%), Positives = 85/206 (41%), Gaps = 6/206 (2%)
Frame = +1
Query: 166 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNL 345
S ++ LL T + ++ W+Q KL PGP P+P GN L L + ++ N
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSRGKLP---PGPTPLPFIGNYLQL---NTEQMYNS 57
Query: 346 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 516
+ ++ +G V + LG + +V L D + E +++ E F WL G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATF-DWLFKGYGV 116
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
S+G + + R+ F I L+ F G+ + E+++ E G D G
Sbjct: 117 AFSNGERAKQLRR-----FSIATLRGF-GV---GKRGIEERIQEEAGFLIDALRGTHGAN 167
Query: 697 VD---ILLETAMGISRKTQDESXFDY 765
+D L T + FDY
Sbjct: 168 IDPTFFLSRTVSNVISSIVFGDRFDY 193
>M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 50.8 bits (116), Expect = 7e-06
Identities = 50/221 (22%), Positives = 94/221 (42%), Gaps = 5/221 (2%)
Frame = +1
Query: 166 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNL 345
S ++ LL T + ++ WQQ KL PGP P+P GN L L + + +
Sbjct: 4 SGLLLVALLACLTVMVLMSVWQQRKSRGKLP---PGPTPLPFIGNYLQL---NTEHICDS 57
Query: 346 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 516
+ +++ +G V + LG + +V L D + E +++ E F W+ G G+
Sbjct: 58 IMKFSECYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATF-DWVFKGYGV 116
Query: 517 LISSGPKWRS-HRKMIAPTFHINILKSFV-GIFNQNSNNVVEKLKSEVGKTFDVHDYMSG 690
S+G + + R IA + K + + S ++E ++S G D ++S
Sbjct: 117 AFSNGERAKQLLRFAIATLRDFGVGKRGIEERIQEESGFLIEAIRSSHGANIDPTFFLSR 176
Query: 691 TTVDILLETAMGISRKTQDESXFDYAMAVMKCAISSTKXTT 813
T +++ G R ++ F +++M T +T
Sbjct: 177 TVSNVISSIVFG-DRFDYEDKEFLSLLSMMLGIFQFTSTST 216
>AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13
variant 5 protein.
Length = 494
Score = 50.8 bits (116), Expect = 7e-06
Identities = 50/221 (22%), Positives = 94/221 (42%), Gaps = 5/221 (2%)
Frame = +1
Query: 166 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNL 345
S ++ LL T + ++ W+Q KL PGP P+P GN L L + ++ N
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSRGKLP---PGPTPLPFIGNYLQL---NTEQMYNS 57
Query: 346 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 516
+ ++ +G V + LG + +V L D + E +++ E F WL G G+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATF-DWLFKGYGV 116
Query: 517 LISSGPKWRSHRKM-IAPTFHINILKSFV-GIFNQNSNNVVEKLKSEVGKTFDVHDYMSG 690
S+G + + R+ IA + K + + + ++E L+ G D ++S
Sbjct: 117 AFSNGERAKQLRRFSIATLRGFGVGKRGIEERIQEEAGFLIEALRGTHGANIDPTFFLSR 176
Query: 691 TTVDILLETAMGISRKTQDESXFDYAMAVMKCAISSTKXTT 813
T +++ G R ++ F + +M + T +T
Sbjct: 177 TVSNVISSIVFG-DRFDYEDKEFLSLLRMMLGSFQFTATST 216
>EF122242-1|ABO41977.1| 321|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 321
Score = 50.0 bits (114), Expect = 1e-05
Identities = 47/174 (27%), Positives = 81/174 (46%), Gaps = 10/174 (5%)
Frame = +1
Query: 259 ELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDI- 435
+L PGP P+PI GN L L + +++ ++ +G++ V LG + +V L+ +
Sbjct: 29 KLPPGPRPLPILGNLLLLCSQ---DMLTSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAVK 85
Query: 436 EIILNSHVHIDKATEY-KFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSF-VG-- 603
E +++ +Y FF G G+ SSG +W+ R+ F I IL++F +G
Sbjct: 86 EALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQ-----FSIQILRNFGMGKR 140
Query: 604 -----IFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAMGISRKTQDE 750
I + S + E K+E G+ FD +S + +I+ G DE
Sbjct: 141 SIEERILEEGSFLLAELRKTE-GEPFDPTFVLSRSVSNIICSVLFGSRFDYDDE 193
>BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 7 protein.
Length = 494
Score = 50.0 bits (114), Expect = 1e-05
Identities = 51/221 (23%), Positives = 93/221 (42%), Gaps = 5/221 (2%)
Frame = +1
Query: 166 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNL 345
S ++ LL T + ++ WQQ KL PGP P+P GN L L + + +
Sbjct: 4 SGLLLVALLACLTVMVLMSVWQQRKSRGKLP---PGPTPLPFIGNYLQL---NTEHICDS 57
Query: 346 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWL--GEGL 516
+ +++ +G V + LG + V L D + E +++ E F W+ G G+
Sbjct: 58 IMKFSECYGPVFTIHLGPRRAVVLCGHDAVREALVDQAEEFSGRGEQATF-DWVFKGYGV 116
Query: 517 LISSGPKWRS-HRKMIAPTFHINILKSFV-GIFNQNSNNVVEKLKSEVGKTFDVHDYMSG 690
S+G + + R IA + K + + S ++E ++S G D ++S
Sbjct: 117 AFSNGERAKQLLRFAIATLRDFGVGKRGIEERIQEESGFLIEAIRSTHGANIDPTFFLSR 176
Query: 691 TTVDILLETAMGISRKTQDESXFDYAMAVMKCAISSTKXTT 813
T +++ G R ++ F ++VM T +T
Sbjct: 177 TVSNVISSIVFG-DRFDYEDKEFLSLLSVMLGIFQFTSTST 216
>BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family
46, subfamily A, polypeptide 1 protein.
Length = 500
Score = 50.0 bits (114), Expect = 1e-05
Identities = 45/169 (26%), Positives = 83/169 (49%), Gaps = 12/169 (7%)
Frame = +1
Query: 259 ELLPGPA-PIPIFGNALTLMRKSP---HELVNLALGYAQTFGNVVRVWLGSKLIVFLADA 426
E +PGP P + G+ +K L ++ L +A+ +G VVRV + K V +
Sbjct: 31 EHIPGPPRPSFLLGHLPCFWKKDEVGGRVLQDVFLDWAKKYGPVVRVNVFHKTSVIVTSP 90
Query: 427 DDIEIILNSHVHIDKATEYKFFKPWLGEGL----LIS--SGPKWRSHRKMIAPTFHINIL 588
+ ++ L S + + Y+ + GE L L+S + +W R++I F + L
Sbjct: 91 ESVKKFLMSTKYNKDSKMYRALQTVFGERLFGQGLVSECNYERWHKQRRVIDLAFSRSSL 150
Query: 589 KSFVGIFNQNSNNVVEKLKSEV-GKT-FDVHDYMSGTTVDILLETAMGI 729
S + FN+ + +VE L+++ G+T + D ++ T +DIL + A G+
Sbjct: 151 VSLMETFNEKAEQLVEILEAKADGQTPVSMQDMLTYTAMDILAKAAFGM 199
>AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxylase
protein.
Length = 500
Score = 50.0 bits (114), Expect = 1e-05
Identities = 45/169 (26%), Positives = 83/169 (49%), Gaps = 12/169 (7%)
Frame = +1
Query: 259 ELLPGPA-PIPIFGNALTLMRKSP---HELVNLALGYAQTFGNVVRVWLGSKLIVFLADA 426
E +PGP P + G+ +K L ++ L +A+ +G VVRV + K V +
Sbjct: 31 EHIPGPPRPSFLLGHLPCFWKKDEVGGRVLQDVFLDWAKKYGPVVRVNVFHKTSVIVTSP 90
Query: 427 DDIEIILNSHVHIDKATEYKFFKPWLGEGL----LIS--SGPKWRSHRKMIAPTFHINIL 588
+ ++ L S + + Y+ + GE L L+S + +W R++I F + L
Sbjct: 91 ESVKKFLMSTKYNKDSKMYRALQTVFGERLFGQGLVSECNYERWHKQRRVIDLAFSRSSL 150
Query: 589 KSFVGIFNQNSNNVVEKLKSEV-GKT-FDVHDYMSGTTVDILLETAMGI 729
S + FN+ + +VE L+++ G+T + D ++ T +DIL + A G+
Sbjct: 151 VSLMETFNEKAEQLVEILEAKADGQTPVSMQDMLTYTAMDILAKAAFGM 199
>J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrome
P450IIE1 (ethanol-inducible) gene, complete cds. ).
Length = 493
Score = 47.2 bits (107), Expect = 8e-05
Identities = 37/136 (27%), Positives = 61/136 (44%), Gaps = 9/136 (6%)
Frame = +1
Query: 190 LGLTTA--IWILY-----RWQQNSHMHKLAELLPGPAPIPIFGNALTL-MRKSPHELVNL 345
LG+T A +W + W+Q +H L PGP P+PI GN L ++ P L
Sbjct: 4 LGVTVALLVWAAFLLLVSMWRQ---VHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRL 60
Query: 346 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWLGEGLLI 522
AQ FG V +++GS+ +V + + E +L+ + F G++
Sbjct: 61 ----AQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIF 116
Query: 523 SSGPKWRSHRKMIAPT 570
++GP W+ R+ T
Sbjct: 117 NNGPTWKDIRRFSLTT 132
>J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrome
P-450j mRNA, complete cds. ).
Length = 493
Score = 47.2 bits (107), Expect = 8e-05
Identities = 37/136 (27%), Positives = 61/136 (44%), Gaps = 9/136 (6%)
Frame = +1
Query: 190 LGLTTA--IWILY-----RWQQNSHMHKLAELLPGPAPIPIFGNALTL-MRKSPHELVNL 345
LG+T A +W + W+Q +H L PGP P+PI GN L ++ P L
Sbjct: 4 LGVTVALLVWAAFLLLVSMWRQ---VHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRL 60
Query: 346 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWLGEGLLI 522
AQ FG V +++GS+ +V + + E +L+ + F G++
Sbjct: 61 ----AQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIF 116
Query: 523 SSGPKWRSHRKMIAPT 570
++GP W+ R+ T
Sbjct: 117 NNGPTWKDIRRFSLTT 132
>DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 47.2 bits (107), Expect = 8e-05
Identities = 37/136 (27%), Positives = 61/136 (44%), Gaps = 9/136 (6%)
Frame = +1
Query: 190 LGLTTA--IWILY-----RWQQNSHMHKLAELLPGPAPIPIFGNALTL-MRKSPHELVNL 345
LG+T A +W + W+Q +H L PGP P+PI GN L ++ P L
Sbjct: 4 LGVTVALLVWAAFLLLVSMWRQ---VHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRL 60
Query: 346 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWLGEGLLI 522
AQ FG V +++GS+ +V + + E +L+ + F G++
Sbjct: 61 ----AQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIF 116
Query: 523 SSGPKWRSHRKMIAPT 570
++GP W+ R+ T
Sbjct: 117 NNGPTWKDIRRFSLTT 132
>DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1
protein.
Length = 493
Score = 47.2 bits (107), Expect = 8e-05
Identities = 37/136 (27%), Positives = 61/136 (44%), Gaps = 9/136 (6%)
Frame = +1
Query: 190 LGLTTA--IWILY-----RWQQNSHMHKLAELLPGPAPIPIFGNALTL-MRKSPHELVNL 345
LG+T A +W + W+Q +H L PGP P+PI GN L ++ P L
Sbjct: 4 LGVTVALLVWAAFLLLVSMWRQ---VHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRL 60
Query: 346 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWLGEGLLI 522
AQ FG V +++GS+ +V + + E +L+ + F G++
Sbjct: 61 ----AQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIF 116
Query: 523 SSGPKWRSHRKMIAPT 570
++GP W+ R+ T
Sbjct: 117 NNGPTWKDIRRFSLTT 132
>BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 47.2 bits (107), Expect = 8e-05
Identities = 37/136 (27%), Positives = 61/136 (44%), Gaps = 9/136 (6%)
Frame = +1
Query: 190 LGLTTA--IWILY-----RWQQNSHMHKLAELLPGPAPIPIFGNALTL-MRKSPHELVNL 345
LG+T A +W + W+Q +H L PGP P+PI GN L ++ P L
Sbjct: 4 LGVTVALLVWAAFLLLVSMWRQ---VHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRL 60
Query: 346 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWLGEGLLI 522
AQ FG V +++GS+ +V + + E +L+ + F G++
Sbjct: 61 ----AQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIF 116
Query: 523 SSGPKWRSHRKMIAPT 570
++GP W+ R+ T
Sbjct: 117 NNGPAWKDIRRFSLTT 132
>AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 47.2 bits (107), Expect = 8e-05
Identities = 37/136 (27%), Positives = 61/136 (44%), Gaps = 9/136 (6%)
Frame = +1
Query: 190 LGLTTA--IWILY-----RWQQNSHMHKLAELLPGPAPIPIFGNALTL-MRKSPHELVNL 345
LG+T A +W + W+Q +H L PGP P+PI GN L ++ P L
Sbjct: 4 LGVTVALLVWAAFLLLVSMWRQ---VHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRL 60
Query: 346 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWLGEGLLI 522
AQ FG V +++GS+ +V + + E +L+ + F G++
Sbjct: 61 ----AQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIF 116
Query: 523 SSGPKWRSHRKMIAPT 570
++GP W+ R+ T
Sbjct: 117 NNGPTWKDIRRFSLTT 132
>AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1
protein.
Length = 493
Score = 47.2 bits (107), Expect = 8e-05
Identities = 37/136 (27%), Positives = 61/136 (44%), Gaps = 9/136 (6%)
Frame = +1
Query: 190 LGLTTA--IWILY-----RWQQNSHMHKLAELLPGPAPIPIFGNALTL-MRKSPHELVNL 345
LG+T A +W + W+Q +H L PGP P+PI GN L ++ P L
Sbjct: 4 LGVTVALLVWAAFLLLVSMWRQ---VHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRL 60
Query: 346 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWLGEGLLI 522
AQ FG V +++GS+ +V + + E +L+ + F G++
Sbjct: 61 ----AQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIF 116
Query: 523 SSGPKWRSHRKMIAPT 570
++GP W+ R+ T
Sbjct: 117 NNGPTWKDIRRFSLTT 132
>EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 491
Score = 46.8 bits (106), Expect = 1e-04
Identities = 46/174 (26%), Positives = 80/174 (45%), Gaps = 10/174 (5%)
Frame = +1
Query: 259 ELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDI- 435
+L PGP P+ I GN L L + +++ ++ +G++ V LG + +V L+ +
Sbjct: 29 KLPPGPRPLSILGNLLLLCSQ---DMLTSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAVK 85
Query: 436 EIILNSHVHIDKATEY-KFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSF-VG-- 603
E +++ +Y FF G G+ SSG +W+ R+ F I IL++F +G
Sbjct: 86 EALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQ-----FSIQILRNFGMGKR 140
Query: 604 -----IFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAMGISRKTQDE 750
I + S + E K+E G+ FD +S + +I+ G DE
Sbjct: 141 SIEERILEEGSFLLAELRKTE-GEPFDPTFVLSRSVSNIICSVLFGSRFDYDDE 193
>BC109056-1|AAI09057.1| 320|Homo sapiens CYP2F1 protein protein.
Length = 320
Score = 46.8 bits (106), Expect = 1e-04
Identities = 46/174 (26%), Positives = 80/174 (45%), Gaps = 10/174 (5%)
Frame = +1
Query: 259 ELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDI- 435
+L PGP P+ I GN L L + +++ ++ +G++ V LG + +V L+ +
Sbjct: 29 KLPPGPRPLSILGNLLLLCSQ---DMLTSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAVK 85
Query: 436 EIILNSHVHIDKATEY-KFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSF-VG-- 603
E +++ +Y FF G G+ SSG +W+ R+ F I IL++F +G
Sbjct: 86 EALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQ-----FSIQILRNFGMGKR 140
Query: 604 -----IFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAMGISRKTQDE 750
I + S + E K+E G+ FD +S + +I+ G DE
Sbjct: 141 SIEERILEEGSFLLAELRKTE-GEPFDPTFVLSRSVSNIICSVLFGSRFDYDDE 193
>AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1
protein.
Length = 495
Score = 46.8 bits (106), Expect = 1e-04
Identities = 46/174 (26%), Positives = 80/174 (45%), Gaps = 10/174 (5%)
Frame = +1
Query: 259 ELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDI- 435
+L PGP P+ I GN L L + +++ ++ +G++ V LG + +V L+ +
Sbjct: 29 KLPPGPRPLSILGNLLLLCSQ---DMLTSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAVK 85
Query: 436 EIILNSHVHIDKATEY-KFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSF-VG-- 603
E +++ +Y FF G G+ SSG +W+ R+ F I IL++F +G
Sbjct: 86 EALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQ-----FSIQILRNFGMGKR 140
Query: 604 -----IFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAMGISRKTQDE 750
I + S + E K+E G+ FD +S + +I+ G DE
Sbjct: 141 SIEERILEEGSFLLAELRKTE-GEPFDPTFVLSRSVSNIICSVLFGSRFDYDDE 193
>U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450
monooxygenase CYP2J2 protein.
Length = 502
Score = 45.6 bits (103), Expect = 2e-04
Identities = 39/167 (23%), Positives = 71/167 (42%), Gaps = 7/167 (4%)
Frame = +1
Query: 268 PGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDIEIIL 447
PGP +P GN + + H V L + + +GN+ + LG V + + +I
Sbjct: 45 PGPWRLPFLGNFFLVDFEQSHLEVQL---FVKKYGNLFSLELGDISAVLITG---LPLIK 98
Query: 448 NSHVHIDKATEYKFFKP-----WLGEGLLISSGPKWRSHRKMIAPTFHINIL--KSFVGI 606
+ +H+D+ + P + GL++SSG W+ R+ L KS
Sbjct: 99 EALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEER 158
Query: 607 FNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAMGISRKTQD 747
+ + ++ E +K E G+ FD H ++ +I+ G + QD
Sbjct: 159 IQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQD 205
>J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein.
Length = 491
Score = 45.6 bits (103), Expect = 2e-04
Identities = 45/174 (25%), Positives = 80/174 (45%), Gaps = 10/174 (5%)
Frame = +1
Query: 259 ELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDI- 435
+L PGP P+ I GN L L + +++ ++ +G++ V LG + +V L+ +
Sbjct: 29 KLPPGPRPLSILGNLLLLCSQ---DMLTSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAVK 85
Query: 436 EIILNSHVHIDKATEY-KFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSF-VG-- 603
E +++ +Y FF G G+ SSG +W+ R+ F I IL++F +G
Sbjct: 86 EALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQ-----FSIQILRNFGMGKR 140
Query: 604 -----IFNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAMGISRKTQDE 750
I + S + + K+E G+ FD +S + +I+ G DE
Sbjct: 141 SIEERILEEGSFLLADVRKTE-GEPFDPTFVLSRSVSNIICSVLFGSRFDYDDE 193
>BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 45.6 bits (103), Expect = 2e-04
Identities = 37/136 (27%), Positives = 60/136 (44%), Gaps = 9/136 (6%)
Frame = +1
Query: 190 LGLTTA--IWILY-----RWQQNSHMHKLAELLPGPAPIPIFGNALTL-MRKSPHELVNL 345
LG+T A +W + W+Q +H L PGP P+PI GN L ++ P L
Sbjct: 4 LGVTVALLVWAAFLLLVSMWRQ---VHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRL 60
Query: 346 ALGYAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFFKPWLGEGLLI 522
AQ FG V + +GS+ +V + + E +L+ + F G++
Sbjct: 61 ----AQRFGPVFTLCVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIF 116
Query: 523 SSGPKWRSHRKMIAPT 570
++GP W+ R+ T
Sbjct: 117 NNGPTWKDIRRFSLTT 132
>BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 45.6 bits (103), Expect = 2e-04
Identities = 39/167 (23%), Positives = 71/167 (42%), Gaps = 7/167 (4%)
Frame = +1
Query: 268 PGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDIEIIL 447
PGP +P GN + + H V L + + +GN+ + LG V + + +I
Sbjct: 45 PGPWRLPFLGNFFLVDFEQSHLEVQL---FVKKYGNLFSLELGDISAVLITG---LPLIK 98
Query: 448 NSHVHIDKATEYKFFKP-----WLGEGLLISSGPKWRSHRKMIAPTFHINIL--KSFVGI 606
+ +H+D+ + P + GL++SSG W+ R+ L KS
Sbjct: 99 EALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEER 158
Query: 607 FNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAMGISRKTQD 747
+ + ++ E +K E G+ FD H ++ +I+ G + QD
Sbjct: 159 IQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQD 205
>AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 45.6 bits (103), Expect = 2e-04
Identities = 39/167 (23%), Positives = 71/167 (42%), Gaps = 7/167 (4%)
Frame = +1
Query: 268 PGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDIEIIL 447
PGP +P GN + + H V L + + +GN+ + LG V + + +I
Sbjct: 45 PGPWRLPFLGNFFLVDFEQSHLEVQL---FVKKYGNLFSLELGDISAVLITG---LPLIK 98
Query: 448 NSHVHIDKATEYKFFKP-----WLGEGLLISSGPKWRSHRKMIAPTFHINIL--KSFVGI 606
+ +H+D+ + P + GL++SSG W+ R+ L KS
Sbjct: 99 EALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEER 158
Query: 607 FNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAMGISRKTQD 747
+ + ++ E +K E G+ FD H ++ +I+ G + QD
Sbjct: 159 IQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQD 205
>AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein.
Length = 502
Score = 45.6 bits (103), Expect = 2e-04
Identities = 39/167 (23%), Positives = 71/167 (42%), Gaps = 7/167 (4%)
Frame = +1
Query: 268 PGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDIEIIL 447
PGP +P GN + + H V L + + +GN+ + LG V + + +I
Sbjct: 45 PGPWRLPFLGNFFLVDFEQSHLEVQL---FVKKYGNLFSLELGDISAVLITG---LPLIK 98
Query: 448 NSHVHIDKATEYKFFKP-----WLGEGLLISSGPKWRSHRKMIAPTFHINIL--KSFVGI 606
+ +H+D+ + P + GL++SSG W+ R+ L KS
Sbjct: 99 EALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEER 158
Query: 607 FNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAMGISRKTQD 747
+ + ++ E +K E G+ FD H ++ +I+ G + QD
Sbjct: 159 IQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQD 205
>AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2
protein.
Length = 502
Score = 45.6 bits (103), Expect = 2e-04
Identities = 39/167 (23%), Positives = 71/167 (42%), Gaps = 7/167 (4%)
Frame = +1
Query: 268 PGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDIEIIL 447
PGP +P GN + + H V L + + +GN+ + LG V + + +I
Sbjct: 45 PGPWRLPFLGNFFLVDFEQSHLEVQL---FVKKYGNLFSLELGDISAVLITG---LPLIK 98
Query: 448 NSHVHIDKATEYKFFKP-----WLGEGLLISSGPKWRSHRKMIAPTFHINIL--KSFVGI 606
+ +H+D+ + P + GL++SSG W+ R+ L KS
Sbjct: 99 EALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEER 158
Query: 607 FNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAMGISRKTQD 747
+ + ++ E +K E G+ FD H ++ +I+ G + QD
Sbjct: 159 IQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQD 205
>AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein.
Length = 430
Score = 44.8 bits (101), Expect = 4e-04
Identities = 28/117 (23%), Positives = 57/117 (48%), Gaps = 4/117 (3%)
Frame = +1
Query: 394 GSKLIVFLADADDIEIILNSHVHIDKATEYKFFKP--WLGEGLLISSGPKWRSHRKMIAP 567
G + ++ + D D I+ +L + T + F P ++ + I+ +W+ R +++P
Sbjct: 4 GQQPVLAITDPDMIKTVLVKECY-SVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSP 62
Query: 568 TFHINILKSFVGIFNQNSNNVVEKLK--SEVGKTFDVHDYMSGTTVDILLETAMGIS 732
TF LK V I Q + +V L+ +E GK + D ++D++ T+ G++
Sbjct: 63 TFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVN 119
>M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 44.4 bits (100), Expect = 6e-04
Identities = 34/125 (27%), Positives = 59/125 (47%), Gaps = 2/125 (1%)
Frame = +1
Query: 202 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVV 381
+ +++L W+Q+S +L GP P+PI GN L L K ++ +++ +G V
Sbjct: 12 SCLFLLSLWRQSSGRGRLPS---GPTPLPIIGNILQLDVK---DMSKSLTNFSKVYGPVF 65
Query: 382 RVWLGSKLIVFLADADDIEIILNSH--VHIDKATEYKFFKPWLGEGLLISSGPKWRSHRK 555
V+ G K IV L + ++ L H + + K G G+L S+G +W+ R+
Sbjct: 66 TVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRR 125
Query: 556 MIAPT 570
T
Sbjct: 126 FCLMT 130
>L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18
protein.
Length = 490
Score = 44.4 bits (100), Expect = 6e-04
Identities = 34/125 (27%), Positives = 59/125 (47%), Gaps = 2/125 (1%)
Frame = +1
Query: 202 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVV 381
+ +++L W+Q+S +L GP P+PI GN L L K ++ +++ +G V
Sbjct: 12 SCLFLLSLWRQSSGRGRLPS---GPTPLPIIGNILQLDVK---DMSKSLTNFSKVYGPVF 65
Query: 382 RVWLGSKLIVFLADADDIEIILNSH--VHIDKATEYKFFKPWLGEGLLISSGPKWRSHRK 555
V+ G K IV L + ++ L H + + K G G+L S+G +W+ R+
Sbjct: 66 TVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRR 125
Query: 556 MIAPT 570
T
Sbjct: 126 FCLMT 130
>BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein.
Length = 431
Score = 44.4 bits (100), Expect = 6e-04
Identities = 34/125 (27%), Positives = 59/125 (47%), Gaps = 2/125 (1%)
Frame = +1
Query: 202 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVV 381
+ +++L W+Q+S +L GP P+PI GN L L K ++ +++ +G V
Sbjct: 12 SCLFLLSLWRQSSGRGRLPS---GPTPLPIIGNILQLDVK---DMSKSLTNFSKVYGPVF 65
Query: 382 RVWLGSKLIVFLADADDIEIILNSH--VHIDKATEYKFFKPWLGEGLLISSGPKWRSHRK 555
V+ G K IV L + ++ L H + + K G G+L S+G +W+ R+
Sbjct: 66 TVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRR 125
Query: 556 MIAPT 570
T
Sbjct: 126 FCLMT 130
>BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein.
Length = 443
Score = 44.4 bits (100), Expect = 6e-04
Identities = 34/125 (27%), Positives = 59/125 (47%), Gaps = 2/125 (1%)
Frame = +1
Query: 202 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVV 381
+ +++L W+Q+S +L GP P+PI GN L L K ++ +++ +G V
Sbjct: 12 SCLFLLSLWRQSSGRGRLPS---GPTPLPIIGNILQLDVK---DMSKSLTNFSKVYGPVF 65
Query: 382 RVWLGSKLIVFLADADDIEIILNSH--VHIDKATEYKFFKPWLGEGLLISSGPKWRSHRK 555
V+ G K IV L + ++ L H + + K G G+L S+G +W+ R+
Sbjct: 66 TVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRR 125
Query: 556 MIAPT 570
T
Sbjct: 126 FCLMT 130
>BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 44.4 bits (100), Expect = 6e-04
Identities = 34/125 (27%), Positives = 59/125 (47%), Gaps = 2/125 (1%)
Frame = +1
Query: 202 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVV 381
+ +++L W+Q+S +L GP P+PI GN L L K ++ +++ +G V
Sbjct: 12 SCLFLLSLWRQSSGRGRLPS---GPTPLPIIGNILQLDVK---DMSKSLTNFSKVYGPVF 65
Query: 382 RVWLGSKLIVFLADADDIEIILNSH--VHIDKATEYKFFKPWLGEGLLISSGPKWRSHRK 555
V+ G K IV L + ++ L H + + K G G+L S+G +W+ R+
Sbjct: 66 TVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRR 125
Query: 556 MIAPT 570
T
Sbjct: 126 FCLMT 130
>BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 44.4 bits (100), Expect = 6e-04
Identities = 34/125 (27%), Positives = 59/125 (47%), Gaps = 2/125 (1%)
Frame = +1
Query: 202 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVV 381
+ +++L W+Q+S +L GP P+PI GN L L K ++ +++ +G V
Sbjct: 12 SCLFLLSLWRQSSGRGRLPS---GPTPLPIIGNILQLDVK---DMSKSLTNFSKVYGPVF 65
Query: 382 RVWLGSKLIVFLADADDIEIILNSH--VHIDKATEYKFFKPWLGEGLLISSGPKWRSHRK 555
V+ G K IV L + ++ L H + + K G G+L S+G +W+ R+
Sbjct: 66 TVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRR 125
Query: 556 MIAPT 570
T
Sbjct: 126 FCLMT 130
>BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 44.4 bits (100), Expect = 6e-04
Identities = 34/125 (27%), Positives = 59/125 (47%), Gaps = 2/125 (1%)
Frame = +1
Query: 202 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVV 381
+ +++L W+Q+S +L GP P+PI GN L L K ++ +++ +G V
Sbjct: 12 SCLFLLSLWRQSSGRGRLPS---GPTPLPIIGNILQLDVK---DMSKSLTNFSKVYGPVF 65
Query: 382 RVWLGSKLIVFLADADDIEIILNSH--VHIDKATEYKFFKPWLGEGLLISSGPKWRSHRK 555
V+ G K IV L + ++ L H + + K G G+L S+G +W+ R+
Sbjct: 66 TVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRR 125
Query: 556 MIAPT 570
T
Sbjct: 126 FCLMT 130
>AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 44.4 bits (100), Expect = 6e-04
Identities = 34/125 (27%), Positives = 59/125 (47%), Gaps = 2/125 (1%)
Frame = +1
Query: 202 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVV 381
+ +++L W+Q+S +L GP P+PI GN L L K ++ +++ +G V
Sbjct: 12 SCLFLLSLWRQSSGRGRLPS---GPTPLPIIGNILQLDVK---DMSKSLTNFSKVYGPVF 65
Query: 382 RVWLGSKLIVFLADADDIEIILNSH--VHIDKATEYKFFKPWLGEGLLISSGPKWRSHRK 555
V+ G K IV L + ++ L H + + K G G+L S+G +W+ R+
Sbjct: 66 TVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRR 125
Query: 556 MIAPT 570
T
Sbjct: 126 FCLMT 130
>AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 variant protein.
Length = 490
Score = 44.0 bits (99), Expect = 8e-04
Identities = 34/125 (27%), Positives = 58/125 (46%), Gaps = 2/125 (1%)
Frame = +1
Query: 202 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVV 381
+ +++L W Q+S +L GP P+PI GN L L K ++ +++ +G V
Sbjct: 12 SCLFLLSLWGQSSGRGRLPS---GPTPLPIIGNILQLDVK---DMSKSLTNFSKVYGPVF 65
Query: 382 RVWLGSKLIVFLADADDIEIILNSH--VHIDKATEYKFFKPWLGEGLLISSGPKWRSHRK 555
V+ G K IV L + ++ L H + + K G G+L S+G +W+ R+
Sbjct: 66 TVYFGLKPIVVLHGYEAVKEALIDHGEEFFGRGSFPVAEKVNKGLGILFSNGKRWKEIRR 125
Query: 556 MIAPT 570
T
Sbjct: 126 FCLMT 130
>AF144566-1|AAD30164.1| 339|Homo sapiens cytochrome P450
epoxygenase protein.
Length = 339
Score = 44.0 bits (99), Expect = 8e-04
Identities = 38/167 (22%), Positives = 70/167 (41%), Gaps = 7/167 (4%)
Frame = +1
Query: 268 PGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDIEIIL 447
PGP +P GN + + H V L + + +GN+ + LG V + + +I
Sbjct: 14 PGPWRLPFLGNFFLVDFEQSHLEVQL---FVKKYGNLFSLELGDISAVLITG---LPLIK 67
Query: 448 NSHVHIDKATEYKFFKP-----WLGEGLLISSGPKWRSHRKMIAPTFHINIL--KSFVGI 606
+ +H+D+ + P + GL++SSG W+ R+ L K
Sbjct: 68 EALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKKGLEER 127
Query: 607 FNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAMGISRKTQD 747
+ + ++ E +K E G+ FD H ++ +I+ G + QD
Sbjct: 128 IQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQD 174
>AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1
protein.
Length = 462
Score = 44.0 bits (99), Expect = 8e-04
Identities = 29/105 (27%), Positives = 48/105 (45%), Gaps = 2/105 (1%)
Frame = +1
Query: 262 LLPGPAPIPIFGNALTL-MRKSPHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDI- 435
L PGP P+PI GN L ++ P L AQ FG V +++GS+ +V + +
Sbjct: 1 LPPGPFPLPIIGNLFQLELKNIPKSFTRL----AQRFGPVFTLYVGSQRMVVMHGYKAVK 56
Query: 436 EIILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPT 570
E +L+ + F G++ ++GP W+ R+ T
Sbjct: 57 EALLDYKDEFSGRGDLPAFHAHRDRGIIFNNGPTWKDIRRFSLTT 101
>BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family 2,
subfamily S, polypeptide 1 protein.
Length = 504
Score = 43.6 bits (98), Expect = 0.001
Identities = 37/168 (22%), Positives = 69/168 (41%), Gaps = 5/168 (2%)
Frame = +1
Query: 262 LLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVVRVWLGS-KLIVFLADADDIE 438
L PGP P+P+ GN L L P L + + ++ +G V ++LG + +V L + +
Sbjct: 32 LPPGPTPLPLLGNLLQL---RPGALYSGLMRLSKKYGPVFTIYLGPWRPVVVLVGQEAVR 88
Query: 439 IILNSHVH--IDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVG--I 606
L + T + G G+ S+G +WR RK + G +
Sbjct: 89 EALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRKFTMLALRDLGMGKREGEEL 148
Query: 607 FNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAMGISRKTQDE 750
+ +VE + G+ FD ++ T +++ G+ +D+
Sbjct: 149 IQAEARCLVETFQGTEGRPFDPSLLLAQATSNVVCSLLFGLRFSYEDK 196
>AY513607-1|AAR90938.1| 100|Homo sapiens truncated cytochrome P450
2A13 variant 4 protein.
Length = 100
Score = 43.6 bits (98), Expect = 0.001
Identities = 29/106 (27%), Positives = 51/106 (48%)
Frame = +1
Query: 166 SRVIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNL 345
S ++ LL T + ++ W+Q KL PGP P+P GN L L + ++ N
Sbjct: 4 SGLLLVTLLACLTVMVLMSVWRQRKSRGKLP---PGPTPLPFIGNYLQL---NTEQMYNS 57
Query: 346 ALGYAQTFGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDKATEY 483
+ ++ +G V + LG + +V L D ++ L +D+A E+
Sbjct: 58 LMKISERYGPVFTIHLGPRRVVVLCGHDAVKEAL-----VDQAEEF 98
>AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein.
Length = 504
Score = 43.6 bits (98), Expect = 0.001
Identities = 37/168 (22%), Positives = 69/168 (41%), Gaps = 5/168 (2%)
Frame = +1
Query: 262 LLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVVRVWLGS-KLIVFLADADDIE 438
L PGP P+P+ GN L L P L + + ++ +G V ++LG + +V L + +
Sbjct: 32 LPPGPTPLPLLGNLLQL---RPGALYSGLMRLSKKYGPVFTIYLGPWRPVVVLVGQEAVR 88
Query: 439 IILNSHVH--IDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVG--I 606
L + T + G G+ S+G +WR RK + G +
Sbjct: 89 EALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRKFTMLALRDLGMGKREGEEL 148
Query: 607 FNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAMGISRKTQDE 750
+ +VE + G+ FD ++ T +++ G+ +D+
Sbjct: 149 IQAEARCLVETFQGTEGRPFDPSLLLAQATSNVVCSLLFGLRFSYEDK 196
>AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens
cDNA FLJ14699 fis, clone NT2RP2006571, moderately
similar to CYTOCHROME P450 2G1 (EC 1.14.14.1). ).
Length = 564
Score = 43.6 bits (98), Expect = 0.001
Identities = 37/168 (22%), Positives = 69/168 (41%), Gaps = 5/168 (2%)
Frame = +1
Query: 262 LLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVVRVWLGS-KLIVFLADADDIE 438
L PGP P+P+ GN L L P L + + ++ +G V ++LG + +V L + +
Sbjct: 32 LPPGPTPLPLLGNLLQL---RPGALYSGLMRLSKKYGPVFTIYLGPWRPVVVLVGQEAVR 88
Query: 439 IILNSHVH--IDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVG--I 606
L + T + G G+ S+G +WR RK + G +
Sbjct: 89 EALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRKFTMLALRDLGMGKREGEEL 148
Query: 607 FNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAMGISRKTQDE 750
+ +VE + G+ FD ++ T +++ G+ +D+
Sbjct: 149 IQAEARCLVETFQGTEGRPFDPSLLLAQATSNVVCSLLFGLRFSYEDK 196
>AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1
protein.
Length = 504
Score = 43.6 bits (98), Expect = 0.001
Identities = 37/168 (22%), Positives = 69/168 (41%), Gaps = 5/168 (2%)
Frame = +1
Query: 262 LLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVVRVWLGS-KLIVFLADADDIE 438
L PGP P+P+ GN L L P L + + ++ +G V ++LG + +V L + +
Sbjct: 32 LPPGPTPLPLLGNLLQL---RPGALYSGLMRLSKKYGPVFTIYLGPWRPVVVLVGQEAVR 88
Query: 439 IILNSHVH--IDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPTFHINILKSFVG--I 606
L + T + G G+ S+G +WR RK + G +
Sbjct: 89 EALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRKFTMLALRDLGMGKREGEEL 148
Query: 607 FNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAMGISRKTQDE 750
+ +VE + G+ FD ++ T +++ G+ +D+
Sbjct: 149 IQAEARCLVETFQGTEGRPFDPSLLLAQATSNVVCSLLFGLRFSYEDK 196
>S63426-1|ABB76283.1| 214|Homo sapiens (S)-mephenytoin hydroxylase
associated cytochrome P450 protein.
Length = 214
Score = 42.3 bits (95), Expect = 0.002
Identities = 32/116 (27%), Positives = 56/116 (48%), Gaps = 2/116 (1%)
Frame = +1
Query: 202 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVV 381
+ +++L W+Q+S +L GP P+PI GN L L K ++ +++ +G V
Sbjct: 12 SCLFLLSLWRQSSGRGRLPS---GPTPLPIIGNILQLDVK---DMSKSLTNFSKVYGPVF 65
Query: 382 RVWLGSKLIVFLADADDIEIILNSH--VHIDKATEYKFFKPWLGEGLLISSGPKWR 543
V+ G K IV L + ++ L H + + K G G+L S+G +W+
Sbjct: 66 TVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWK 121
>BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 42.3 bits (95), Expect = 0.002
Identities = 32/133 (24%), Positives = 60/133 (45%), Gaps = 3/133 (2%)
Frame = +1
Query: 181 YPLLGLTTAIWILYR-WQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGY 357
+ +L L + +L+ W+Q+ KL PGP P+PI GN L + K ++ +
Sbjct: 4 FVVLVLCLSFMLLFSLWRQSCRRRKLP---PGPTPLPIIGNMLQIDVK---DICKSFTNF 57
Query: 358 AQTFGNVVRVWLGSKLIVFLADADDIE--IILNSHVHIDKATEYKFFKPWLGEGLLISSG 531
++ +G V V+ G IV + ++ +I N + + G G++ S+G
Sbjct: 58 SKVYGPVFTVYFGMNPIVVFHGYESVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNG 117
Query: 532 PKWRSHRKMIAPT 570
+W+ R+ T
Sbjct: 118 KRWKEIRRFSLTT 130
>Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein.
Length = 490
Score = 41.5 bits (93), Expect = 0.004
Identities = 32/133 (24%), Positives = 60/133 (45%), Gaps = 3/133 (2%)
Frame = +1
Query: 181 YPLLGLTTAIWILYR-WQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGY 357
+ +L L + +L+ W+Q+ KL PGP P+PI GN L + K ++ +
Sbjct: 4 FVVLVLCLSFMLLFSLWRQSCRRRKLP---PGPTPLPIIGNMLQIDVK---DICKSFTNF 57
Query: 358 AQTFGNVVRVWLGSKLIVFLADADDIE--IILNSHVHIDKATEYKFFKPWLGEGLLISSG 531
++ +G V V+ G IV + ++ +I N + + G G++ S+G
Sbjct: 58 SKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNG 117
Query: 532 PKWRSHRKMIAPT 570
+W+ R+ T
Sbjct: 118 KRWKEIRRFSLTT 130
>M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 41.5 bits (93), Expect = 0.004
Identities = 32/121 (26%), Positives = 59/121 (48%), Gaps = 3/121 (2%)
Frame = +1
Query: 202 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTL-MRKSPHELVNLALGYAQTFGNV 378
+ + +L W+Q+S KL PGP P+P+ GN L + ++ L NL ++ +G V
Sbjct: 7 SCLLLLSLWRQSSGRGKLP---PGPTPLPVIGNILQIGIKDISKSLTNL----SKVYGPV 59
Query: 379 VRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSGPKWRSHR 552
++ G K IV L + + E +++ + + G G++ S+G KW+ R
Sbjct: 60 FTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIR 119
Query: 553 K 555
+
Sbjct: 120 R 120
>M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 41.5 bits (93), Expect = 0.004
Identities = 32/121 (26%), Positives = 59/121 (48%), Gaps = 3/121 (2%)
Frame = +1
Query: 202 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTL-MRKSPHELVNLALGYAQTFGNV 378
+ + +L W+Q+S KL PGP P+P+ GN L + ++ L NL ++ +G V
Sbjct: 7 SCLLLLSLWRQSSGRGKLP---PGPTPLPVIGNILQIGIKDISKSLTNL----SKVYGPV 59
Query: 379 VRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSGPKWRSHR 552
++ G K IV L + + E +++ + + G G++ S+G KW+ R
Sbjct: 60 FTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIR 119
Query: 553 K 555
+
Sbjct: 120 R 120
>L16880-1|AAD13466.1| 273|Homo sapiens cytochrome P-450 2C protein.
Length = 273
Score = 41.5 bits (93), Expect = 0.004
Identities = 32/121 (26%), Positives = 59/121 (48%), Gaps = 3/121 (2%)
Frame = +1
Query: 202 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTL-MRKSPHELVNLALGYAQTFGNV 378
+ + +L W+Q+S KL PGP P+P+ GN L + ++ L NL ++ +G V
Sbjct: 12 SCLLLLSLWRQSSGRGKLP---PGPTPLPVIGNILQIGIKDISKSLTNL----SKVYGPV 64
Query: 379 VRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSGPKWRSHR 552
++ G K IV L + + E +++ + + G G++ S+G KW+ R
Sbjct: 65 FTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIR 124
Query: 553 K 555
+
Sbjct: 125 R 125
>D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein.
Length = 487
Score = 41.5 bits (93), Expect = 0.004
Identities = 32/121 (26%), Positives = 59/121 (48%), Gaps = 3/121 (2%)
Frame = +1
Query: 202 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTL-MRKSPHELVNLALGYAQTFGNV 378
+ + +L W+Q+S KL PGP P+P+ GN L + ++ L NL ++ +G V
Sbjct: 9 SCLLLLSLWRQSSGRGKLP---PGPTPLPVIGNILQIGIKDISKSLTNL----SKVYGPV 61
Query: 379 VRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSGPKWRSHR 552
++ G K IV L + + E +++ + + G G++ S+G KW+ R
Sbjct: 62 FTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIR 121
Query: 553 K 555
+
Sbjct: 122 R 122
>BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 41.5 bits (93), Expect = 0.004
Identities = 32/121 (26%), Positives = 59/121 (48%), Gaps = 3/121 (2%)
Frame = +1
Query: 202 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTL-MRKSPHELVNLALGYAQTFGNV 378
+ + +L W+Q+S KL PGP P+P+ GN L + ++ L NL ++ +G V
Sbjct: 12 SCLLLLSLWRQSSGRGKLP---PGPTPLPVIGNILQIGIKDISKSLTNL----SKVYGPV 64
Query: 379 VRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSGPKWRSHR 552
++ G K IV L + + E +++ + + G G++ S+G KW+ R
Sbjct: 65 FTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIR 124
Query: 553 K 555
+
Sbjct: 125 R 125
>BC070317-1|AAH70317.1| 162|Homo sapiens CYP2C9 protein protein.
Length = 162
Score = 41.5 bits (93), Expect = 0.004
Identities = 32/121 (26%), Positives = 59/121 (48%), Gaps = 3/121 (2%)
Frame = +1
Query: 202 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTL-MRKSPHELVNLALGYAQTFGNV 378
+ + +L W+Q+S KL PGP P+P+ GN L + ++ L NL ++ +G V
Sbjct: 12 SCLLLLSLWRQSSGRGKLP---PGPTPLPVIGNILQIGIKDISKSLTNL----SKVYGPV 64
Query: 379 VRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSGPKWRSHR 552
++ G K IV L + + E +++ + + G G++ S+G KW+ R
Sbjct: 65 FTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIR 124
Query: 553 K 555
+
Sbjct: 125 R 125
>BC020754-1|AAH20754.1| 162|Homo sapiens CYP2C9 protein protein.
Length = 162
Score = 41.5 bits (93), Expect = 0.004
Identities = 32/121 (26%), Positives = 59/121 (48%), Gaps = 3/121 (2%)
Frame = +1
Query: 202 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTL-MRKSPHELVNLALGYAQTFGNV 378
+ + +L W+Q+S KL PGP P+P+ GN L + ++ L NL ++ +G V
Sbjct: 12 SCLLLLSLWRQSSGRGKLP---PGPTPLPVIGNILQIGIKDISKSLTNL----SKVYGPV 64
Query: 379 VRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSGPKWRSHR 552
++ G K IV L + + E +++ + + G G++ S+G KW+ R
Sbjct: 65 FTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIR 124
Query: 553 K 555
+
Sbjct: 125 R 125
>AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 41.5 bits (93), Expect = 0.004
Identities = 32/121 (26%), Positives = 59/121 (48%), Gaps = 3/121 (2%)
Frame = +1
Query: 202 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTL-MRKSPHELVNLALGYAQTFGNV 378
+ + +L W+Q+S KL PGP P+P+ GN L + ++ L NL ++ +G V
Sbjct: 12 SCLLLLSLWRQSSGRGKLP---PGPTPLPVIGNILQIGIKDISKSLTNL----SKVYGPV 64
Query: 379 VRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSGPKWRSHR 552
++ G K IV L + + E +++ + + G G++ S+G KW+ R
Sbjct: 65 FTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIR 124
Query: 553 K 555
+
Sbjct: 125 R 125
>AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 41.5 bits (93), Expect = 0.004
Identities = 32/133 (24%), Positives = 60/133 (45%), Gaps = 3/133 (2%)
Frame = +1
Query: 181 YPLLGLTTAIWILYR-WQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGY 357
+ +L L + +L+ W+Q+ KL PGP P+PI GN L + K ++ +
Sbjct: 4 FVVLVLCLSFMLLFSLWRQSCRRRKLP---PGPTPLPIIGNMLQIDVK---DICKSFTNF 57
Query: 358 AQTFGNVVRVWLGSKLIVFLADADDIE--IILNSHVHIDKATEYKFFKPWLGEGLLISSG 531
++ +G V V+ G IV + ++ +I N + + G G++ S+G
Sbjct: 58 SKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNG 117
Query: 532 PKWRSHRKMIAPT 570
+W+ R+ T
Sbjct: 118 KRWKEIRRFSLTT 130
>AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 41.5 bits (93), Expect = 0.004
Identities = 32/121 (26%), Positives = 59/121 (48%), Gaps = 3/121 (2%)
Frame = +1
Query: 202 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTL-MRKSPHELVNLALGYAQTFGNV 378
+ + +L W+Q+S KL PGP P+P+ GN L + ++ L NL ++ +G V
Sbjct: 12 SCLLLLSLWRQSSGRGKLP---PGPTPLPVIGNILQIGIKDISKSLTNL----SKVYGPV 64
Query: 379 VRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSGPKWRSHR 552
++ G K IV L + + E +++ + + G G++ S+G KW+ R
Sbjct: 65 FTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIR 124
Query: 553 K 555
+
Sbjct: 125 R 125
>AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 41.5 bits (93), Expect = 0.004
Identities = 32/133 (24%), Positives = 60/133 (45%), Gaps = 3/133 (2%)
Frame = +1
Query: 181 YPLLGLTTAIWILYR-WQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGY 357
+ +L L + +L+ W+Q+ KL PGP P+PI GN L + K ++ +
Sbjct: 4 FVVLVLCLSFMLLFSLWRQSCRRRKLP---PGPTPLPIIGNMLQIDVK---DICKSFTNF 57
Query: 358 AQTFGNVVRVWLGSKLIVFLADADDIE--IILNSHVHIDKATEYKFFKPWLGEGLLISSG 531
++ +G V V+ G IV + ++ +I N + + G G++ S+G
Sbjct: 58 SKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNG 117
Query: 532 PKWRSHRKMIAPT 570
+W+ R+ T
Sbjct: 118 KRWKEIRRFSLTT 130
>AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 41.5 bits (93), Expect = 0.004
Identities = 32/121 (26%), Positives = 59/121 (48%), Gaps = 3/121 (2%)
Frame = +1
Query: 202 TAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTL-MRKSPHELVNLALGYAQTFGNV 378
+ + +L W+Q+S KL PGP P+P+ GN L + ++ L NL ++ +G V
Sbjct: 12 SCLLLLSLWRQSSGRGKLP---PGPTPLPVIGNILQIGIKDISKSLTNL----SKVYGPV 64
Query: 379 VRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSGPKWRSHR 552
++ G K IV L + + E +++ + + G G++ S+G KW+ R
Sbjct: 65 FTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIR 124
Query: 553 K 555
+
Sbjct: 125 R 125
>S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein.
Length = 477
Score = 41.1 bits (92), Expect = 0.005
Identities = 32/117 (27%), Positives = 57/117 (48%), Gaps = 3/117 (2%)
Frame = +1
Query: 214 ILYRWQQNSHMHKLAELLPGPAPIPIFGNALTL-MRKSPHELVNLALGYAQTFGNVVRVW 390
+L W+Q+S KL PGP P+P+ GN L + ++ L NL ++ +G V ++
Sbjct: 3 LLSLWRQSSGRGKLP---PGPTPLPVIGNILQIGIKDISKSLTNL----SKVYGPVFTLY 55
Query: 391 LGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISSGPKWRSHRK 555
G K IV L + + E +++ + + G G++ S+G KW+ R+
Sbjct: 56 FGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRR 112
>M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrome
P-450 1 mRNA, complete cds, clone Hp1-2. ).
Length = 393
Score = 41.1 bits (92), Expect = 0.005
Identities = 31/128 (24%), Positives = 59/128 (46%), Gaps = 3/128 (2%)
Frame = +1
Query: 181 YPLLGLTTAIWILYR-WQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGY 357
+ +L L + +L+ W+Q+ KL PGP P+PI GN L + K ++ +
Sbjct: 4 FVVLVLCLSFMLLFSLWRQSCRRRKLP---PGPTPLPIIGNMLQIDVK---DICKSFTNF 57
Query: 358 AQTFGNVVRVWLGSKLIVFLADADDIE--IILNSHVHIDKATEYKFFKPWLGEGLLISSG 531
++ +G V V+ G IV + ++ +I N + + G G++ S+G
Sbjct: 58 SKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNG 117
Query: 532 PKWRSHRK 555
+W+ R+
Sbjct: 118 KRWKEIRR 125
>M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrome
P-450 1 functional form mRNA, complete cds. ).
Length = 490
Score = 41.1 bits (92), Expect = 0.005
Identities = 31/128 (24%), Positives = 59/128 (46%), Gaps = 3/128 (2%)
Frame = +1
Query: 181 YPLLGLTTAIWILYR-WQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGY 357
+ +L L + +L+ W+Q+ KL PGP P+PI GN L + K ++ +
Sbjct: 4 FVVLVLCLSFMLLFSLWRQSCRRRKLP---PGPTPLPIIGNMLQIDVK---DICKSFTNF 57
Query: 358 AQTFGNVVRVWLGSKLIVFLADADDIE--IILNSHVHIDKATEYKFFKPWLGEGLLISSG 531
++ +G V V+ G IV + ++ +I N + + G G++ S+G
Sbjct: 58 SKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNG 117
Query: 532 PKWRSHRK 555
+W+ R+
Sbjct: 118 KRWKEIRR 125
>AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 variant protein.
Length = 512
Score = 41.1 bits (92), Expect = 0.005
Identities = 42/140 (30%), Positives = 68/140 (48%), Gaps = 5/140 (3%)
Frame = +1
Query: 268 PGPAPIPIFGNALTLMRKSPHELVNLALG-YAQTFGNVVRVWLGSKLIVFLADADDIE-- 438
PGP P+ G+ LTL K+PH LAL +Q +G+V+++ +GS +V L+ D I
Sbjct: 41 PGPWDWPLIGHMLTL-GKNPH----LALSRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQA 95
Query: 439 IILNSHVHIDKATEYKFFKPWLGEGLLIS--SGPKWRSHRKMIAPTFHINILKSFVGIFN 612
++ + Y F G+ + S SGP W + R++ N LKSF I +
Sbjct: 96 LVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQ-----NGLKSF-SIAS 149
Query: 613 QNSNNVVEKLKSEVGKTFDV 672
+++ L+ V K +V
Sbjct: 150 DPASSTSCYLEEHVSKEAEV 169
>M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein.
Length = 480
Score = 40.7 bits (91), Expect = 0.007
Identities = 29/117 (24%), Positives = 52/117 (44%), Gaps = 2/117 (1%)
Frame = +1
Query: 226 WQQNSHMHKLAELLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVVRVWLGSKL 405
W+Q+ KL PGP P+PI GN L + K ++ +++ +G V V+ G
Sbjct: 10 WRQSCRRRKLP---PGPTPLPIIGNMLQIDVK---DICKSFTNFSKVYGPVFTVYFGMNP 63
Query: 406 IVFLADADDIE--IILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPT 570
IV + ++ +I N + + G G++ S+G +W+ R+ T
Sbjct: 64 IVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTT 120
>AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 variant protein.
Length = 512
Score = 40.7 bits (91), Expect = 0.007
Identities = 42/140 (30%), Positives = 68/140 (48%), Gaps = 5/140 (3%)
Frame = +1
Query: 268 PGPAPIPIFGNALTLMRKSPHELVNLALG-YAQTFGNVVRVWLGSKLIVFLADADDIE-- 438
PGP P+ G+ LTL K+PH LAL +Q +G+V+++ +GS +V L+ D I
Sbjct: 41 PGPWDWPLIGHMLTL-GKNPH----LALSRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQA 95
Query: 439 IILNSHVHIDKATEYKFFKPWLGEGLLIS--SGPKWRSHRKMIAPTFHINILKSFVGIFN 612
++ + Y F G+ + S SGP W + R++ N LKSF I +
Sbjct: 96 LVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQ-----NGLKSF-SIAS 149
Query: 613 QNSNNVVEKLKSEVGKTFDV 672
+++ L+ V K +V
Sbjct: 150 DPASSTSCYLEEHVSKGAEV 169
>BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family 2,
subfamily W, polypeptide 1 protein.
Length = 490
Score = 40.3 bits (90), Expect = 0.009
Identities = 31/105 (29%), Positives = 48/105 (45%), Gaps = 2/105 (1%)
Frame = +1
Query: 268 PGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDIEIIL 447
PGP P+P+ GN L L+R S + + L ++ +G V V LG + V L + ++ L
Sbjct: 33 PGPRPLPLVGN-LHLLRLSQQDRSLMEL--SERYGPVFTVHLGRQKTVVLTGFEAVKEAL 89
Query: 448 NSHVH--IDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPTFH 576
D+ F G G+ SSG +WR+ R+ H
Sbjct: 90 AGPGQELADRPPIAIFQLIQRGGGIFFSSGARWRAARQFTVRALH 134
>AB209749-1|BAD92986.1| 210|Homo sapiens cytochrome P450, family 46
variant protein.
Length = 210
Score = 39.1 bits (87), Expect = 0.021
Identities = 25/90 (27%), Positives = 48/90 (53%), Gaps = 3/90 (3%)
Frame = +1
Query: 469 KATEYKFFKPWLGEGLLISSG-PKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLK 645
+A + F + G+GL+ +W R++I F + L S + FN+ + +VE L+
Sbjct: 81 RALQTVFGERLFGQGLVSECNYERWHKQRRVIDLAFSRSSLVSLMETFNEKAEQLVEILE 140
Query: 646 SEV-GKT-FDVHDYMSGTTVDILLETAMGI 729
++ G+T + D ++ T +DIL + A G+
Sbjct: 141 AKADGQTPVSMQDMLTYTAMDILAKAAFGM 170
>M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 38.7 bits (86), Expect = 0.028
Identities = 31/129 (24%), Positives = 62/129 (48%), Gaps = 3/129 (2%)
Frame = +1
Query: 178 FYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTL-MRKSPHELVNLALG 354
F L+ + + +L W+Q+S KL PGP P+P+ GN L + ++ L NL
Sbjct: 4 FVVLVLCLSCLLLLSIWRQSSGRGKLP---PGPTPLPVIGNILQIDIKDVSKSLTNL--- 57
Query: 355 YAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISS 528
++ +G V ++ G + +V L + + E +++ + + G G++ S+
Sbjct: 58 -SKIYGPVFTLYFGLERMVVLHGYEVVKEALIDLGEEFSGRGHFPLAERANRGFGIVFSN 116
Query: 529 GPKWRSHRK 555
G +W+ R+
Sbjct: 117 GKRWKEIRR 125
>L39098-1|AAL31347.1| 160|Homo sapiens S-mephenytoin 4-hydroxylase
protein.
Length = 160
Score = 38.7 bits (86), Expect = 0.028
Identities = 31/129 (24%), Positives = 62/129 (48%), Gaps = 3/129 (2%)
Frame = +1
Query: 178 FYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTL-MRKSPHELVNLALG 354
F L+ + + +L W+Q+S KL PGP P+P+ GN L + ++ L NL
Sbjct: 4 FVVLVLCLSCLLLLSIWRQSSGRGKLP---PGPTPLPVIGNILQIDIKDVSKSLTNL--- 57
Query: 355 YAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISS 528
++ +G V ++ G + +V L + + E +++ + + G G++ S+
Sbjct: 58 -SKIYGPVFTLYFGLERMVVLHGYEVVKEALIDLGEEFSGRGHFPLAERANRGFGIVFSN 116
Query: 529 GPKWRSHRK 555
G +W+ R+
Sbjct: 117 GKRWKEIRR 125
>AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 38.7 bits (86), Expect = 0.028
Identities = 31/129 (24%), Positives = 62/129 (48%), Gaps = 3/129 (2%)
Frame = +1
Query: 178 FYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTL-MRKSPHELVNLALG 354
F L+ + + +L W+Q+S KL PGP P+P+ GN L + ++ L NL
Sbjct: 4 FVVLVLCLSCLLLLSIWRQSSGRGKLP---PGPTPLPVIGNILQIDIKDVSKSLTNL--- 57
Query: 355 YAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISS 528
++ +G V ++ G + +V L + + E +++ + + G G++ S+
Sbjct: 58 -SKIYGPVFTLYFGLERMVVLHGYEVVKEALIDLGEEFSGRGHFPLAERANRGFGIVFSN 116
Query: 529 GPKWRSHRK 555
G +W+ R+
Sbjct: 117 GKRWKEIRR 125
>AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 38.7 bits (86), Expect = 0.028
Identities = 31/129 (24%), Positives = 62/129 (48%), Gaps = 3/129 (2%)
Frame = +1
Query: 178 FYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTL-MRKSPHELVNLALG 354
F L+ + + +L W+Q+S KL PGP P+P+ GN L + ++ L NL
Sbjct: 4 FVVLVLCLSCLLLLSIWRQSSGRGKLP---PGPTPLPVIGNILQIDIKDVSKSLTNL--- 57
Query: 355 YAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISS 528
++ +G V ++ G + +V L + + E +++ + + G G++ S+
Sbjct: 58 -SKIYGPVFTLYFGLERMVVLHGYEVVKEALIDLGEEFSGRGHFPLAERANRGFGIVFSN 116
Query: 529 GPKWRSHRK 555
G +W+ R+
Sbjct: 117 GKRWKEIRR 125
>AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 38.7 bits (86), Expect = 0.028
Identities = 31/129 (24%), Positives = 62/129 (48%), Gaps = 3/129 (2%)
Frame = +1
Query: 178 FYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTL-MRKSPHELVNLALG 354
F L+ + + +L W+Q+S KL PGP P+P+ GN L + ++ L NL
Sbjct: 4 FVVLVLCLSCLLLLSIWRQSSGRGKLP---PGPTPLPVIGNILQIDIKDVSKSLTNL--- 57
Query: 355 YAQTFGNVVRVWLGSKLIVFLADADDI-EIILNSHVHIDKATEYKFF-KPWLGEGLLISS 528
++ +G V ++ G + +V L + + E +++ + + G G++ S+
Sbjct: 58 -SKIYGPVFTLYFGLERMVVLHGYEVVKEALIDLGEEFSGRGHFPLAERANRGFGIVFSN 116
Query: 529 GPKWRSHRK 555
G +W+ R+
Sbjct: 117 GKRWKEIRR 125
>BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 37.9 bits (84), Expect = 0.050
Identities = 41/173 (23%), Positives = 71/173 (41%), Gaps = 7/173 (4%)
Frame = +1
Query: 268 PGPAPIPIFGNALTLMRKS--PHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDIE- 438
PGP +P GN +L S PH + +Q +G + + LG V L D ++
Sbjct: 41 PGPPGLPFIGNIYSLAASSELPHVYMR---KQSQVYGEIFSLDLGGISTVVLNGYDVVKE 97
Query: 439 -IILNSHVHIDKATEYKFFKPWLGEGLLISS-GPKWRSHRKMIAPTFHI--NILKSFVGI 606
++ S + D+ F K GLL S G W HR++ +F KSF
Sbjct: 98 CLVHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRGWVDHRRLAVNSFRYFGYGQKSFESK 157
Query: 607 FNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAMGISRKTQDESXFDY 765
+ + + +++ G+ FD ++ +I G R T +++ F +
Sbjct: 158 ILEETKFFNDAIETYKGRPFDFKQLITNAVSNITNLIIFG-ERFTYEDTDFQH 209
>BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 37.9 bits (84), Expect = 0.050
Identities = 41/173 (23%), Positives = 71/173 (41%), Gaps = 7/173 (4%)
Frame = +1
Query: 268 PGPAPIPIFGNALTLMRKS--PHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDIE- 438
PGP +P GN +L S PH + +Q +G + + LG V L D ++
Sbjct: 41 PGPPGLPFIGNIYSLAASSELPHVYMR---KQSQVYGEIFSLDLGGISTVVLNGYDVVKE 97
Query: 439 -IILNSHVHIDKATEYKFFKPWLGEGLLISS-GPKWRSHRKMIAPTFHI--NILKSFVGI 606
++ S + D+ F K GLL S G W HR++ +F KSF
Sbjct: 98 CLVHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRGWVDHRRLAVNSFRYFGYGQKSFESK 157
Query: 607 FNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAMGISRKTQDESXFDY 765
+ + + +++ G+ FD ++ +I G R T +++ F +
Sbjct: 158 ILEETKFFNDAIETYKGRPFDFKQLITNAVSNITNLIIFG-ERFTYEDTDFQH 209
>AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1
protein.
Length = 501
Score = 37.9 bits (84), Expect = 0.050
Identities = 41/173 (23%), Positives = 71/173 (41%), Gaps = 7/173 (4%)
Frame = +1
Query: 268 PGPAPIPIFGNALTLMRKS--PHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDIE- 438
PGP +P GN +L S PH + +Q +G + + LG V L D ++
Sbjct: 41 PGPPGLPFIGNIYSLAASSELPHVYMR---KQSQVYGEIFSLDLGGISTVVLNGYDVVKE 97
Query: 439 -IILNSHVHIDKATEYKFFKPWLGEGLLISS-GPKWRSHRKMIAPTFHI--NILKSFVGI 606
++ S + D+ F K GLL S G W HR++ +F KSF
Sbjct: 98 CLVHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRGWVDHRRLAVNSFRYFGYGQKSFESK 157
Query: 607 FNQNSNNVVEKLKSEVGKTFDVHDYMSGTTVDILLETAMGISRKTQDESXFDY 765
+ + + +++ G+ FD ++ +I G R T +++ F +
Sbjct: 158 ILEETKFFNDAIETYKGRPFDFKQLITNAVSNITNLIIFG-ERFTYEDTDFQH 209
>M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein.
Length = 462
Score = 37.5 bits (83), Expect = 0.066
Identities = 26/105 (24%), Positives = 47/105 (44%), Gaps = 2/105 (1%)
Frame = +1
Query: 262 LLPGPAPIPIFGNALTLMRKSPHELVNLALGYAQTFGNVVRVWLGSKLIVFLADADDIE- 438
L PGP P+PI GN L + K ++ +++ +G V V+ G IV + ++
Sbjct: 1 LPPGPTPLPIIGNMLQIDVK---DICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKE 57
Query: 439 -IILNSHVHIDKATEYKFFKPWLGEGLLISSGPKWRSHRKMIAPT 570
+I N + + G G++ S+G +W+ R+ T
Sbjct: 58 ALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTT 102
>AF280107-1|AAG32291.1| 106|Homo sapiens cytochrome P450
polypeptide 43 protein.
Length = 106
Score = 34.7 bits (76), Expect = 0.46
Identities = 24/86 (27%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSHMHKLAELL--PGPAPIPIFGNALTLMRKSPHELVNLALGYAQTF 369
+ T++ +LY + +H HKL + L PGP P+P G L +R L N + +
Sbjct: 15 VATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLR----GLWNFDRECNEKY 68
Query: 370 GNVVRVWLGSKLIVFLADADDIEIIL 447
G + ++ G + ++ + D D I+ +L
Sbjct: 69 GEMWGLYEGQQPMLVIMDPDMIKTVL 94
>BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein.
Length = 393
Score = 34.3 bits (75), Expect = 0.61
Identities = 18/53 (33%), Positives = 32/53 (60%), Gaps = 2/53 (3%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSHMHKLAELL--PGPAPIPIFGNALTLMRKSPHELVNLA 348
+ T++ +LY + +H HKL + L PGP P+P G L +R+S +++ + A
Sbjct: 15 VATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLRRSLNKIPSWA 65
>AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein.
Length = 516
Score = 33.5 bits (73), Expect = 1.1
Identities = 34/133 (25%), Positives = 57/133 (42%), Gaps = 6/133 (4%)
Frame = +1
Query: 190 LGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTL-MRKSPHELVNLALGYAQT 366
L + AI++L + H A PGP P+P GN L + + +P+ L +
Sbjct: 9 LAMIVAIFLLLVDLMHRHQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDV 68
Query: 367 FGNVVRVWLGSKLIVFLADADDIEIILNSHVHIDK--ATEYKF--FKPWLGEGLLISS-G 531
F N+ W ++ LA + ++ D+ A Y+ F P +G+++S G
Sbjct: 69 F-NLQLAWTPVVVLNGLAAVRE-AMVTRGEDTADRPPAPIYQVLGFGP-RSQGVILSRYG 125
Query: 532 PKWRSHRKMIAPT 570
P WR R+ T
Sbjct: 126 PAWREQRRFSVST 138
>DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 31.9 bits (69), Expect = 3.3
Identities = 35/134 (26%), Positives = 53/134 (39%), Gaps = 7/134 (5%)
Frame = +1
Query: 190 LGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNALTL-MRKSPHELVNLALGYAQT 366
L + AI++L + H A PGP P+P GN L + + +P+ L +
Sbjct: 9 LAVIVAIFLLLVDLMHRHQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQL----RRR 64
Query: 367 FGNVVRVWLGSKLIVFLADADDIEIILNSHVH--IDK----ATEYKFFKPWLGEGLLISS 528
FG+V + L +V L + L +H D+ T+ F P L
Sbjct: 65 FGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARY 124
Query: 529 GPKWRSHRKMIAPT 570
GP WR R+ T
Sbjct: 125 GPAWREQRRFSVST 138
>AM086564-1|CAJ31103.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 31.9 bits (69), Expect = 3.3
Identities = 28/130 (21%), Positives = 50/130 (38%), Gaps = 4/130 (3%)
Frame = +1
Query: 349 LGYAQTFGNVVRVWLGSKLIVFLADADDIE-IILNSHVHIDKATE---YKFFKPWLGEGL 516
LG Q FG + R+ LG + +V L IE ++ E YK +
Sbjct: 49 LGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYPDLS 108
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
L W++H+K+ + I S + Q + E+++++ G + + S T
Sbjct: 109 LGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSPLT 168
Query: 697 VDILLETAMG 726
I+ G
Sbjct: 169 CSIICYLTFG 178
>M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein.
Length = 495
Score = 31.5 bits (68), Expect = 4.3
Identities = 28/130 (21%), Positives = 50/130 (38%), Gaps = 4/130 (3%)
Frame = +1
Query: 349 LGYAQTFGNVVRVWLGSKLIVFLADADDIE-IILNSHVHIDKATE---YKFFKPWLGEGL 516
LG Q FG + R+ LG + +V L IE ++ E YK +
Sbjct: 50 LGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSKNYPDLS 109
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
L W++H+K+ + I S + Q + E+++++ G + + S T
Sbjct: 110 LGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLT 169
Query: 697 VDILLETAMG 726
I+ G
Sbjct: 170 CSIICYLTFG 179
>M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein.
Length = 494
Score = 31.5 bits (68), Expect = 4.3
Identities = 28/130 (21%), Positives = 50/130 (38%), Gaps = 4/130 (3%)
Frame = +1
Query: 349 LGYAQTFGNVVRVWLGSKLIVFLADADDIE-IILNSHVHIDKATE---YKFFKPWLGEGL 516
LG Q FG + R+ LG + +V L IE ++ E YK +
Sbjct: 49 LGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSKNYPDLS 108
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
L W++H+K+ + I S + Q + E+++++ G + + S T
Sbjct: 109 LGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLT 168
Query: 697 VDILLETAMG 726
I+ G
Sbjct: 169 CSIICYLTFG 178
>M12792-1|AAB59440.1| 494|Homo sapiens steroid 21-hydroxylase
protein.
Length = 494
Score = 31.5 bits (68), Expect = 4.3
Identities = 28/130 (21%), Positives = 50/130 (38%), Gaps = 4/130 (3%)
Frame = +1
Query: 349 LGYAQTFGNVVRVWLGSKLIVFLADADDIE-IILNSHVHIDKATE---YKFFKPWLGEGL 516
LG Q FG + R+ LG + +V L IE ++ E YK +
Sbjct: 49 LGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSKNYPDLS 108
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
L W++H+K+ + I S + Q + E+++++ G + + S T
Sbjct: 109 LGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLT 168
Query: 697 VDILLETAMG 726
I+ G
Sbjct: 169 CSIICYLTFG 178
>BX679671-8|CAM26070.1| 494|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 494
Score = 31.5 bits (68), Expect = 4.3
Identities = 28/130 (21%), Positives = 50/130 (38%), Gaps = 4/130 (3%)
Frame = +1
Query: 349 LGYAQTFGNVVRVWLGSKLIVFLADADDIE-IILNSHVHIDKATE---YKFFKPWLGEGL 516
LG Q FG + R+ LG + +V L IE ++ E YK +
Sbjct: 49 LGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSKNYPDLS 108
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
L W++H+K+ + I S + Q + E+++++ G + + S T
Sbjct: 109 LGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLT 168
Query: 697 VDILLETAMG 726
I+ G
Sbjct: 169 CSIICYLTFG 178
>BC125182-1|AAI25183.1| 494|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 494
Score = 31.5 bits (68), Expect = 4.3
Identities = 28/130 (21%), Positives = 50/130 (38%), Gaps = 4/130 (3%)
Frame = +1
Query: 349 LGYAQTFGNVVRVWLGSKLIVFLADADDIE-IILNSHVHIDKATE---YKFFKPWLGEGL 516
LG Q FG + R+ LG + +V L IE ++ E YK +
Sbjct: 49 LGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSKNYPDLS 108
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
L W++H+K+ + I S + Q + E+++++ G + + S T
Sbjct: 109 LGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLT 168
Query: 697 VDILLETAMG 726
I+ G
Sbjct: 169 CSIICYLTFG 178
>X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase
protein.
Length = 495
Score = 31.1 bits (67), Expect = 5.7
Identities = 28/130 (21%), Positives = 50/130 (38%), Gaps = 4/130 (3%)
Frame = +1
Query: 349 LGYAQTFGNVVRVWLGSKLIVFLADADDIE-IILNSHVHIDKATE---YKFFKPWLGEGL 516
LG Q FG + R+ LG + +V L IE ++ E YK +
Sbjct: 50 LGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYPDLS 109
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
L W++H+K+ + I S + Q + E+++++ G + + S T
Sbjct: 110 LGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLT 169
Query: 697 VDILLETAMG 726
I+ G
Sbjct: 170 CSIICYLTFG 179
>X58904-1|CAA41707.1| 371|Homo sapiens steroid 21-monooxygenase
protein.
Length = 371
Score = 31.1 bits (67), Expect = 5.7
Identities = 28/130 (21%), Positives = 50/130 (38%), Gaps = 4/130 (3%)
Frame = +1
Query: 349 LGYAQTFGNVVRVWLGSKLIVFLADADDIE-IILNSHVHIDKATE---YKFFKPWLGEGL 516
LG Q FG + R+ LG + +V L IE ++ E YK +
Sbjct: 49 LGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYPDLS 108
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
L W++H+K+ + I S + Q + E+++++ G + + S T
Sbjct: 109 LGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLT 168
Query: 697 VDILLETAMG 726
I+ G
Sbjct: 169 CSIICYLTFG 178
>X58902-1|CAA41706.1| 372|Homo sapiens steroid 21-monooxygenase
protein.
Length = 372
Score = 31.1 bits (67), Expect = 5.7
Identities = 28/130 (21%), Positives = 50/130 (38%), Gaps = 4/130 (3%)
Frame = +1
Query: 349 LGYAQTFGNVVRVWLGSKLIVFLADADDIE-IILNSHVHIDKATE---YKFFKPWLGEGL 516
LG Q FG + R+ LG + +V L IE ++ E YK +
Sbjct: 50 LGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYPDLS 109
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
L W++H+K+ + I S + Q + E+++++ G + + S T
Sbjct: 110 LGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLT 169
Query: 697 VDILLETAMG 726
I+ G
Sbjct: 170 CSIICYLTFG 179
>X58900-1|CAA41704.1| 372|Homo sapiens steroid 21-monooxygenase
protein.
Length = 372
Score = 31.1 bits (67), Expect = 5.7
Identities = 28/130 (21%), Positives = 50/130 (38%), Gaps = 4/130 (3%)
Frame = +1
Query: 349 LGYAQTFGNVVRVWLGSKLIVFLADADDIE-IILNSHVHIDKATE---YKFFKPWLGEGL 516
LG Q FG + R+ LG + +V L IE ++ E YK +
Sbjct: 50 LGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYPDLS 109
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
L W++H+K+ + I S + Q + E+++++ G + + S T
Sbjct: 110 LGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLT 169
Query: 697 VDILLETAMG 726
I+ G
Sbjct: 170 CSIICYLTFG 179
>X54807-1|CAA38578.1| 56|Homo sapiens unspecific monooxygenase
protein.
Length = 56
Score = 31.1 bits (67), Expect = 5.7
Identities = 16/45 (35%), Positives = 25/45 (55%), Gaps = 1/45 (2%)
Frame = +1
Query: 181 YPLLGLTTAIWILYR-WQQNSHMHKLAELLPGPAPIPIFGNALTL 312
+ +L L + +L+ W+Q+ KL PGP P+PI GN L +
Sbjct: 4 FVVLVLCLSFMLLFSLWRQSCRRRKLP---PGPTPLPIIGNMLQI 45
>M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant
21-hydroxylase B gene, complete cds. ).
Length = 495
Score = 31.1 bits (67), Expect = 5.7
Identities = 28/130 (21%), Positives = 50/130 (38%), Gaps = 4/130 (3%)
Frame = +1
Query: 349 LGYAQTFGNVVRVWLGSKLIVFLADADDIE-IILNSHVHIDKATE---YKFFKPWLGEGL 516
LG Q FG + R+ LG + +V L IE ++ E YK +
Sbjct: 50 LGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYPDLS 109
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
L W++H+K+ + I S + Q + E+++++ G + + S T
Sbjct: 110 LGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLT 169
Query: 697 VDILLETAMG 726
I+ G
Sbjct: 170 CSIICYLTFG 179
>M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human
21-hydroxylase B gene, complete cds. ).
Length = 495
Score = 31.1 bits (67), Expect = 5.7
Identities = 28/130 (21%), Positives = 50/130 (38%), Gaps = 4/130 (3%)
Frame = +1
Query: 349 LGYAQTFGNVVRVWLGSKLIVFLADADDIE-IILNSHVHIDKATE---YKFFKPWLGEGL 516
LG Q FG + R+ LG + +V L IE ++ E YK +
Sbjct: 50 LGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYPDLS 109
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
L W++H+K+ + I S + Q + E+++++ G + + S T
Sbjct: 110 LGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLT 169
Query: 697 VDILLETAMG 726
I+ G
Sbjct: 170 CSIICYLTFG 179
>BC125181-1|AAI25182.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 31.1 bits (67), Expect = 5.7
Identities = 28/130 (21%), Positives = 50/130 (38%), Gaps = 4/130 (3%)
Frame = +1
Query: 349 LGYAQTFGNVVRVWLGSKLIVFLADADDIE-IILNSHVHIDKATE---YKFFKPWLGEGL 516
LG Q FG + R+ LG + +V L IE ++ E YK +
Sbjct: 50 LGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYPDLS 109
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
L W++H+K+ + I S + Q + E+++++ G + + S T
Sbjct: 110 LGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLT 169
Query: 697 VDILLETAMG 726
I+ G
Sbjct: 170 CSIICYLTFG 179
>AM183951-1|CAJ75805.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 31.1 bits (67), Expect = 5.7
Identities = 28/130 (21%), Positives = 50/130 (38%), Gaps = 4/130 (3%)
Frame = +1
Query: 349 LGYAQTFGNVVRVWLGSKLIVFLADADDIE-IILNSHVHIDKATE---YKFFKPWLGEGL 516
LG Q FG + R+ LG + +V L IE ++ E YK +
Sbjct: 49 LGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYPDLS 108
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
L W++H+K+ + I S + Q + E+++++ G + + S T
Sbjct: 109 LGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLT 168
Query: 697 VDILLETAMG 726
I+ G
Sbjct: 169 CSIICYLTFG 178
>AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 31.1 bits (67), Expect = 5.7
Identities = 28/130 (21%), Positives = 50/130 (38%), Gaps = 4/130 (3%)
Frame = +1
Query: 349 LGYAQTFGNVVRVWLGSKLIVFLADADDIE-IILNSHVHIDKATE---YKFFKPWLGEGL 516
LG Q FG + R+ LG + +V L IE ++ E YK +
Sbjct: 49 LGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYPDLS 108
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
L W++H+K+ + I S + Q + E+++++ G + + S T
Sbjct: 109 LGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLT 168
Query: 697 VDILLETAMG 726
I+ G
Sbjct: 169 CSIICYLTFG 178
>AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 31.1 bits (67), Expect = 5.7
Identities = 28/130 (21%), Positives = 50/130 (38%), Gaps = 4/130 (3%)
Frame = +1
Query: 349 LGYAQTFGNVVRVWLGSKLIVFLADADDIE-IILNSHVHIDKATE---YKFFKPWLGEGL 516
LG Q FG + R+ LG + +V L IE ++ E YK +
Sbjct: 49 LGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYPDLS 108
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
L W++H+K+ + I S + Q + E+++++ G + + S T
Sbjct: 109 LGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLT 168
Query: 697 VDILLETAMG 726
I+ G
Sbjct: 169 CSIICYLTFG 178
>AM183948-1|CAJ75802.1| 494|Homo sapiens steroid 21-hydroxylase
protein.
Length = 494
Score = 31.1 bits (67), Expect = 5.7
Identities = 28/130 (21%), Positives = 50/130 (38%), Gaps = 4/130 (3%)
Frame = +1
Query: 349 LGYAQTFGNVVRVWLGSKLIVFLADADDIE-IILNSHVHIDKATE---YKFFKPWLGEGL 516
LG Q FG + R+ LG + +V L IE ++ E YK +
Sbjct: 49 LGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYPDLS 108
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
L W++H+K+ + I S + Q + E+++++ G + + S T
Sbjct: 109 LGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLT 168
Query: 697 VDILLETAMG 726
I+ G
Sbjct: 169 CSIICYLTFG 178
>AM183947-1|CAJ75801.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 31.1 bits (67), Expect = 5.7
Identities = 28/130 (21%), Positives = 50/130 (38%), Gaps = 4/130 (3%)
Frame = +1
Query: 349 LGYAQTFGNVVRVWLGSKLIVFLADADDIE-IILNSHVHIDKATE---YKFFKPWLGEGL 516
LG Q FG + R+ LG + +V L IE ++ E YK +
Sbjct: 49 LGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYPDLS 108
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
L W++H+K+ + I S + Q + E+++++ G + + S T
Sbjct: 109 LGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLT 168
Query: 697 VDILLETAMG 726
I+ G
Sbjct: 169 CSIICYLTFG 178
>AM086565-1|CAJ31104.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 31.1 bits (67), Expect = 5.7
Identities = 28/130 (21%), Positives = 50/130 (38%), Gaps = 4/130 (3%)
Frame = +1
Query: 349 LGYAQTFGNVVRVWLGSKLIVFLADADDIE-IILNSHVHIDKATE---YKFFKPWLGEGL 516
LG Q FG + R+ LG + +V L IE ++ E YK +
Sbjct: 49 LGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYPDLS 108
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
L W++H+K+ + I S + Q + E+++++ G + + S T
Sbjct: 109 LGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLT 168
Query: 697 VDILLETAMG 726
I+ G
Sbjct: 169 CSIICYLTFG 178
>AL929593-1|CAI41779.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 31.1 bits (67), Expect = 5.7
Identities = 28/130 (21%), Positives = 50/130 (38%), Gaps = 4/130 (3%)
Frame = +1
Query: 349 LGYAQTFGNVVRVWLGSKLIVFLADADDIE-IILNSHVHIDKATE---YKFFKPWLGEGL 516
LG Q FG + R+ LG + +V L IE ++ E YK +
Sbjct: 50 LGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYPDLS 109
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
L W++H+K+ + I S + Q + E+++++ G + + S T
Sbjct: 110 LGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLT 169
Query: 697 VDILLETAMG 726
I+ G
Sbjct: 170 CSIICYLTFG 179
>AL662849-18|CAI17479.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 31.1 bits (67), Expect = 5.7
Identities = 28/130 (21%), Positives = 50/130 (38%), Gaps = 4/130 (3%)
Frame = +1
Query: 349 LGYAQTFGNVVRVWLGSKLIVFLADADDIE-IILNSHVHIDKATE---YKFFKPWLGEGL 516
LG Q FG + R+ LG + +V L IE ++ E YK +
Sbjct: 50 LGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYPDLS 109
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
L W++H+K+ + I S + Q + E+++++ G + + S T
Sbjct: 110 LGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLT 169
Query: 697 VDILLETAMG 726
I+ G
Sbjct: 170 CSIICYLTFG 179
>AL645922-24|CAI41754.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 31.1 bits (67), Expect = 5.7
Identities = 28/130 (21%), Positives = 50/130 (38%), Gaps = 4/130 (3%)
Frame = +1
Query: 349 LGYAQTFGNVVRVWLGSKLIVFLADADDIE-IILNSHVHIDKATE---YKFFKPWLGEGL 516
LG Q FG + R+ LG + +V L IE ++ E YK +
Sbjct: 50 LGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYPDLS 109
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
L W++H+K+ + I S + Q + E+++++ G + + S T
Sbjct: 110 LGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLT 169
Query: 697 VDILLETAMG 726
I+ G
Sbjct: 170 CSIICYLTFG 179
>AL049547-7|CAB89301.1| 495|Homo sapiens dJ34F7.3 (cytochrome P450,
subfamily XXIA (steroid 21-hydroxylase, congenital a
protein.
Length = 495
Score = 31.1 bits (67), Expect = 5.7
Identities = 28/130 (21%), Positives = 50/130 (38%), Gaps = 4/130 (3%)
Frame = +1
Query: 349 LGYAQTFGNVVRVWLGSKLIVFLADADDIE-IILNSHVHIDKATE---YKFFKPWLGEGL 516
LG Q FG + R+ LG + +V L IE ++ E YK +
Sbjct: 50 LGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYPDLS 109
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
L W++H+K+ + I S + Q + E+++++ G + + S T
Sbjct: 110 LGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLT 169
Query: 697 VDILLETAMG 726
I+ G
Sbjct: 170 CSIICYLTFG 179
>AF280113-1|AAG33014.1| 74|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 74
Score = 31.1 bits (67), Expect = 5.7
Identities = 16/43 (37%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSHMHKLAELL--PGPAPIPIFGNALTLMR 318
+ T++ +LY + +H HKL + L PGP P+P G L +R
Sbjct: 15 VATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLR 55
>AF280112-1|AAG33013.1| 126|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 126
Score = 31.1 bits (67), Expect = 5.7
Identities = 16/43 (37%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Frame = +1
Query: 196 LTTAIWILYRWQQNSHMHKLAELL--PGPAPIPIFGNALTLMR 318
+ T++ +LY + +H HKL + L PGP P+P G L +R
Sbjct: 15 VATSLVLLYIY--GTHSHKLFKKLGIPGPTPLPFLGTILFYLR 55
>AF019413-2|AAB67982.1| 495|Homo sapiens cytochrome P450
21-hydroxylase protein.
Length = 495
Score = 31.1 bits (67), Expect = 5.7
Identities = 28/130 (21%), Positives = 50/130 (38%), Gaps = 4/130 (3%)
Frame = +1
Query: 349 LGYAQTFGNVVRVWLGSKLIVFLADADDIE-IILNSHVHIDKATE---YKFFKPWLGEGL 516
LG Q FG + R+ LG + +V L IE ++ E YK +
Sbjct: 50 LGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYPDLS 109
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
L W++H+K+ + I S + Q + E+++++ G + + S T
Sbjct: 110 LGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLT 169
Query: 697 VDILLETAMG 726
I+ G
Sbjct: 170 CSIICYLTFG 179
>BC004367-1|AAH04367.1| 313|Homo sapiens potassium channel,
subfamily K, member 6 protein.
Length = 313
Score = 30.7 bits (66), Expect = 7.5
Identities = 16/44 (36%), Positives = 22/44 (50%)
Frame = +1
Query: 172 VIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNA 303
V Y LGL + +L ++ S +H L EL+ P P P NA
Sbjct: 238 VTVYLFLGLVAMVLVLQTFRHVSDLHGLTELILLPPPCPASFNA 281
>AK222545-1|BAD96265.1| 313|Homo sapiens potassium channel,
subfamily K, member 6 variant protein.
Length = 313
Score = 30.7 bits (66), Expect = 7.5
Identities = 16/44 (36%), Positives = 22/44 (50%)
Frame = +1
Query: 172 VIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNA 303
V Y LGL + +L ++ S +H L EL+ P P P NA
Sbjct: 238 VTVYLFLGLVAMVLVLQTFRHVSDLHGLTELILLPPPCPASFNA 281
>AJ297404-1|CAC15489.1| 313|Homo sapiens potassium channel,
subfamily K, member 6 (TWIK-2) protein.
Length = 313
Score = 30.7 bits (66), Expect = 7.5
Identities = 16/44 (36%), Positives = 22/44 (50%)
Frame = +1
Query: 172 VIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNA 303
V Y LGL + +L ++ S +H L EL+ P P P NA
Sbjct: 238 VTVYLFLGLVAMVLVLQTFRHVSDLHGLTELILLPPPCPASFNA 281
>AF281303-1|AAG10507.1| 179|Homo sapiens 2P domain K+ channel
TWIK-2 protein.
Length = 179
Score = 30.7 bits (66), Expect = 7.5
Identities = 16/44 (36%), Positives = 22/44 (50%)
Frame = +1
Query: 172 VIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNA 303
V Y LGL + +L ++ S +H L EL+ P P P NA
Sbjct: 104 VTVYLFLGLVAMVLVLQTFRHVSDLHGLTELILLPPPCPASFNA 147
>AF281302-1|AAG10506.1| 313|Homo sapiens 2P domain K+ channel
TWIK-2 protein.
Length = 313
Score = 30.7 bits (66), Expect = 7.5
Identities = 16/44 (36%), Positives = 22/44 (50%)
Frame = +1
Query: 172 VIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNA 303
V Y LGL + +L ++ S +H L EL+ P P P NA
Sbjct: 238 VTVYLFLGLVAMVLVLQTFRHVSDLHGLTELILLPPPCPASFNA 281
>AF134149-1|AAD22980.1| 313|Homo sapiens 2-pore K+ channel subunit
TOSS protein.
Length = 313
Score = 30.7 bits (66), Expect = 7.5
Identities = 16/44 (36%), Positives = 22/44 (50%)
Frame = +1
Query: 172 VIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNA 303
V Y LGL + +L ++ S +H L EL+ P P P NA
Sbjct: 238 VTVYLFLGLVAMVLVLQTFRHVSDLHGLTELILLPPPCPASFNA 281
>AF117708-1|AAD24000.1| 313|Homo sapiens tandem pore domain
potassium channel TWIK-2 protein.
Length = 313
Score = 30.7 bits (66), Expect = 7.5
Identities = 16/44 (36%), Positives = 22/44 (50%)
Frame = +1
Query: 172 VIFYPLLGLTTAIWILYRWQQNSHMHKLAELLPGPAPIPIFGNA 303
V Y LGL + +L ++ S +H L EL+ P P P NA
Sbjct: 238 VTVYLFLGLVAMVLVLQTFRHVSDLHGLTELILLPPPCPASFNA 281
>AM183946-1|CAJ75800.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 30.3 bits (65), Expect = 10.0
Identities = 28/130 (21%), Positives = 50/130 (38%), Gaps = 4/130 (3%)
Frame = +1
Query: 349 LGYAQTFGNVVRVWLGSKLIVFLADADDIE-IILNSHVHIDKATE---YKFFKPWLGEGL 516
LG Q FG + R+ LG + +V L IE ++ E YK +
Sbjct: 49 LGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYPDLS 108
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
L W++H+K+ + I S + Q + E+++++ G + + S T
Sbjct: 109 LGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFRERMRAQPGTPVAIEEEFSLLT 168
Query: 697 VDILLETAMG 726
I+ G
Sbjct: 169 CSIICYLTFG 178
>AM183945-1|CAJ75799.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 30.3 bits (65), Expect = 10.0
Identities = 28/130 (21%), Positives = 50/130 (38%), Gaps = 4/130 (3%)
Frame = +1
Query: 349 LGYAQTFGNVVRVWLGSKLIVFLADADDIE-IILNSHVHIDKATE---YKFFKPWLGEGL 516
LG Q FG + R+ LG + +V L IE ++ E YK +
Sbjct: 49 LGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYPDLS 108
Query: 517 LISSGPKWRSHRKMIAPTFHINILKSFVGIFNQNSNNVVEKLKSEVGKTFDVHDYMSGTT 696
L W++H+K+ + I S + Q + E+++++ G + + S T
Sbjct: 109 LGDYSLLWKAHKKLTRSALLLGIRDSMEPVEEQLTQEFCERMRAQPGTPVAIEEEFSLLT 168
Query: 697 VDILLETAMG 726
I+ G
Sbjct: 169 CSIICYLTFG 178
>AK024290-1|BAB14875.1| 590|Homo sapiens protein ( Homo sapiens
cDNA FLJ14228 fis, clone NT2RP3004148. ).
Length = 590
Score = 30.3 bits (65), Expect = 10.0
Identities = 13/28 (46%), Positives = 18/28 (64%)
Frame = +1
Query: 142 ETEGYHVNSRVIFYPLLGLTTAIWILYR 225
E + V +R +FYPLLGL A+ + YR
Sbjct: 372 EVQRKEVQARAVFYPLLGLGGAVNMCYR 399
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 132,863,367
Number of Sequences: 237096
Number of extensions: 2962050
Number of successful extensions: 5651
Number of sequences better than 10.0: 251
Number of HSP's better than 10.0 without gapping: 5312
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5564
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11603768198
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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