Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP18_F_O04
(899 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U20938-1|AAB51366.1| 1025|Homo sapiens dihydropyrimidine dehydro... 133 7e-31
U09178-1|AAA57474.1| 1025|Homo sapiens dihydropyrimidine dehydro... 133 7e-31
BX908805-1|CAI15125.1| 1025|Homo sapiens dihydropyrimidine dehyd... 133 7e-31
BT006740-1|AAP35386.1| 173|Homo sapiens dihydropyrimidine dehyd... 133 7e-31
BC131778-1|AAI31779.1| 1025|Homo sapiens dihydropyrimidine dehyd... 133 7e-31
BC131777-1|AAI31778.1| 1025|Homo sapiens dihydropyrimidine dehyd... 133 7e-31
BC108742-1|AAI08743.1| 173|Homo sapiens DPYD protein protein. 133 7e-31
BC064027-1|AAH64027.1| 173|Homo sapiens DPYD protein protein. 133 7e-31
BC008379-1|AAH08379.1| 173|Homo sapiens DPYD protein protein. 133 7e-31
AL356457-3|CAH70570.1| 1025|Homo sapiens dihydropyrimidine dehyd... 133 7e-31
AB003063-1|BAA89789.1| 1025|Homo sapiens dihydropyrimidine dehyd... 133 7e-31
>U20938-1|AAB51366.1| 1025|Homo sapiens dihydropyrimidine
dehydrogenase protein.
Length = 1025
Score = 133 bits (322), Expect = 7e-31
Identities = 60/79 (75%), Positives = 65/79 (82%)
Frame = +1
Query: 307 ENVLHVQPXNKNFDDIKHTTLSERGALREAARCLKCADAPCQKSCPTQIDVKSFITSIAN 486
+N + + NFDDIKHTTL ERGALREA RCLKCADAPCQKSCPT +D+KSFITSIAN
Sbjct: 47 KNCFNCEKLENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIAN 106
Query: 487 KNYYGAAKAILSDIPSGLT 543
KNYYGAAK I SD P GLT
Sbjct: 107 KNYYGAAKMIFSDNPLGLT 125
Score = 75.8 bits (178), Expect = 2e-13
Identities = 32/43 (74%), Positives = 35/43 (81%)
Frame = +2
Query: 548 GMVCPTSDLCVGGCNLHATEEGAINIGGLXHFAVDXFMKMGLP 676
GMVCPTSDLCVGGCNL+ATEEG INIGGL FA + F M +P
Sbjct: 127 GMVCPTSDLCVGGCNLYATEEGPINIGGLQQFATEVFKAMSIP 169
Score = 56.8 bits (131), Expect = 1e-07
Identities = 25/59 (42%), Positives = 34/59 (57%)
Frame = +3
Query: 168 MAKLLSKELPDIENLLKLNPTVKPYTNLVPSAQTKKIKXHWKRNADRKCTTCPTLXQEF 344
MA +LSK+ DIE++L LNP + + L ++ K K HWKRN D+ C C L F
Sbjct: 1 MAPVLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENNF 59
>U09178-1|AAA57474.1| 1025|Homo sapiens dihydropyrimidine
dehydrogenase protein.
Length = 1025
Score = 133 bits (322), Expect = 7e-31
Identities = 60/79 (75%), Positives = 65/79 (82%)
Frame = +1
Query: 307 ENVLHVQPXNKNFDDIKHTTLSERGALREAARCLKCADAPCQKSCPTQIDVKSFITSIAN 486
+N + + NFDDIKHTTL ERGALREA RCLKCADAPCQKSCPT +D+KSFITSIAN
Sbjct: 47 KNCFNCEKLENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIAN 106
Query: 487 KNYYGAAKAILSDIPSGLT 543
KNYYGAAK I SD P GLT
Sbjct: 107 KNYYGAAKMIFSDNPLGLT 125
Score = 75.8 bits (178), Expect = 2e-13
Identities = 32/43 (74%), Positives = 35/43 (81%)
Frame = +2
Query: 548 GMVCPTSDLCVGGCNLHATEEGAINIGGLXHFAVDXFMKMGLP 676
GMVCPTSDLCVGGCNL+ATEEG INIGGL FA + F M +P
Sbjct: 127 GMVCPTSDLCVGGCNLYATEEGPINIGGLQQFATEVFKAMSIP 169
Score = 56.8 bits (131), Expect = 1e-07
Identities = 25/59 (42%), Positives = 34/59 (57%)
Frame = +3
Query: 168 MAKLLSKELPDIENLLKLNPTVKPYTNLVPSAQTKKIKXHWKRNADRKCTTCPTLXQEF 344
MA +LSK+ DIE++L LNP + + L ++ K K HWKRN D+ C C L F
Sbjct: 1 MAPVLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENNF 59
>BX908805-1|CAI15125.1| 1025|Homo sapiens dihydropyrimidine
dehydrogenase protein.
Length = 1025
Score = 133 bits (322), Expect = 7e-31
Identities = 60/79 (75%), Positives = 65/79 (82%)
Frame = +1
Query: 307 ENVLHVQPXNKNFDDIKHTTLSERGALREAARCLKCADAPCQKSCPTQIDVKSFITSIAN 486
+N + + NFDDIKHTTL ERGALREA RCLKCADAPCQKSCPT +D+KSFITSIAN
Sbjct: 47 KNCFNCEKLENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIAN 106
Query: 487 KNYYGAAKAILSDIPSGLT 543
KNYYGAAK I SD P GLT
Sbjct: 107 KNYYGAAKMIFSDNPLGLT 125
Score = 75.8 bits (178), Expect = 2e-13
Identities = 32/43 (74%), Positives = 35/43 (81%)
Frame = +2
Query: 548 GMVCPTSDLCVGGCNLHATEEGAINIGGLXHFAVDXFMKMGLP 676
GMVCPTSDLCVGGCNL+ATEEG INIGGL FA + F M +P
Sbjct: 127 GMVCPTSDLCVGGCNLYATEEGPINIGGLQQFATEVFKAMSIP 169
Score = 56.0 bits (129), Expect = 2e-07
Identities = 25/59 (42%), Positives = 34/59 (57%)
Frame = +3
Query: 168 MAKLLSKELPDIENLLKLNPTVKPYTNLVPSAQTKKIKXHWKRNADRKCTTCPTLXQEF 344
MA +LSK+ DIE++L LNP + + L ++ K K HWKRN D+ C C L F
Sbjct: 1 MAPVLSKDSADIESILALNPRTQTHATLRSTSAKKLDKKHWKRNPDKNCFNCEKLENNF 59
>BT006740-1|AAP35386.1| 173|Homo sapiens dihydropyrimidine
dehydrogenase protein.
Length = 173
Score = 133 bits (322), Expect = 7e-31
Identities = 60/79 (75%), Positives = 65/79 (82%)
Frame = +1
Query: 307 ENVLHVQPXNKNFDDIKHTTLSERGALREAARCLKCADAPCQKSCPTQIDVKSFITSIAN 486
+N + + NFDDIKHTTL ERGALREA RCLKCADAPCQKSCPT +D+KSFITSIAN
Sbjct: 47 KNCFNCEKLENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIAN 106
Query: 487 KNYYGAAKAILSDIPSGLT 543
KNYYGAAK I SD P GLT
Sbjct: 107 KNYYGAAKMIFSDNPLGLT 125
Score = 68.9 bits (161), Expect = 2e-11
Identities = 29/35 (82%), Positives = 31/35 (88%)
Frame = +2
Query: 548 GMVCPTSDLCVGGCNLHATEEGAINIGGLXHFAVD 652
GMVCPTSDLCVGGCNL+ATEEG INIGGL FA +
Sbjct: 127 GMVCPTSDLCVGGCNLYATEEGPINIGGLQQFATE 161
Score = 56.8 bits (131), Expect = 1e-07
Identities = 25/59 (42%), Positives = 34/59 (57%)
Frame = +3
Query: 168 MAKLLSKELPDIENLLKLNPTVKPYTNLVPSAQTKKIKXHWKRNADRKCTTCPTLXQEF 344
MA +LSK+ DIE++L LNP + + L ++ K K HWKRN D+ C C L F
Sbjct: 1 MAPVLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENNF 59
>BC131778-1|AAI31779.1| 1025|Homo sapiens dihydropyrimidine
dehydrogenase protein.
Length = 1025
Score = 133 bits (322), Expect = 7e-31
Identities = 60/79 (75%), Positives = 65/79 (82%)
Frame = +1
Query: 307 ENVLHVQPXNKNFDDIKHTTLSERGALREAARCLKCADAPCQKSCPTQIDVKSFITSIAN 486
+N + + NFDDIKHTTL ERGALREA RCLKCADAPCQKSCPT +D+KSFITSIAN
Sbjct: 47 KNCFNCEKLENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIAN 106
Query: 487 KNYYGAAKAILSDIPSGLT 543
KNYYGAAK I SD P GLT
Sbjct: 107 KNYYGAAKMIFSDNPLGLT 125
Score = 75.8 bits (178), Expect = 2e-13
Identities = 32/43 (74%), Positives = 35/43 (81%)
Frame = +2
Query: 548 GMVCPTSDLCVGGCNLHATEEGAINIGGLXHFAVDXFMKMGLP 676
GMVCPTSDLCVGGCNL+ATEEG INIGGL FA + F M +P
Sbjct: 127 GMVCPTSDLCVGGCNLYATEEGPINIGGLQQFATEVFKAMSIP 169
Score = 56.8 bits (131), Expect = 1e-07
Identities = 25/59 (42%), Positives = 34/59 (57%)
Frame = +3
Query: 168 MAKLLSKELPDIENLLKLNPTVKPYTNLVPSAQTKKIKXHWKRNADRKCTTCPTLXQEF 344
MA +LSK+ DIE++L LNP + + L ++ K K HWKRN D+ C C L F
Sbjct: 1 MAPVLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENNF 59
>BC131777-1|AAI31778.1| 1025|Homo sapiens dihydropyrimidine
dehydrogenase protein.
Length = 1025
Score = 133 bits (322), Expect = 7e-31
Identities = 60/79 (75%), Positives = 65/79 (82%)
Frame = +1
Query: 307 ENVLHVQPXNKNFDDIKHTTLSERGALREAARCLKCADAPCQKSCPTQIDVKSFITSIAN 486
+N + + NFDDIKHTTL ERGALREA RCLKCADAPCQKSCPT +D+KSFITSIAN
Sbjct: 47 KNCFNCEKLENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIAN 106
Query: 487 KNYYGAAKAILSDIPSGLT 543
KNYYGAAK I SD P GLT
Sbjct: 107 KNYYGAAKMIFSDNPLGLT 125
Score = 75.8 bits (178), Expect = 2e-13
Identities = 32/43 (74%), Positives = 35/43 (81%)
Frame = +2
Query: 548 GMVCPTSDLCVGGCNLHATEEGAINIGGLXHFAVDXFMKMGLP 676
GMVCPTSDLCVGGCNL+ATEEG INIGGL FA + F M +P
Sbjct: 127 GMVCPTSDLCVGGCNLYATEEGPINIGGLQQFATEVFKAMSIP 169
Score = 56.8 bits (131), Expect = 1e-07
Identities = 25/59 (42%), Positives = 34/59 (57%)
Frame = +3
Query: 168 MAKLLSKELPDIENLLKLNPTVKPYTNLVPSAQTKKIKXHWKRNADRKCTTCPTLXQEF 344
MA +LSK+ DIE++L LNP + + L ++ K K HWKRN D+ C C L F
Sbjct: 1 MAPVLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENNF 59
>BC108742-1|AAI08743.1| 173|Homo sapiens DPYD protein protein.
Length = 173
Score = 133 bits (322), Expect = 7e-31
Identities = 60/79 (75%), Positives = 65/79 (82%)
Frame = +1
Query: 307 ENVLHVQPXNKNFDDIKHTTLSERGALREAARCLKCADAPCQKSCPTQIDVKSFITSIAN 486
+N + + NFDDIKHTTL ERGALREA RCLKCADAPCQKSCPT +D+KSFITSIAN
Sbjct: 47 KNCFNCEKLENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIAN 106
Query: 487 KNYYGAAKAILSDIPSGLT 543
KNYYGAAK I SD P GLT
Sbjct: 107 KNYYGAAKMIFSDNPLGLT 125
Score = 65.7 bits (153), Expect = 2e-10
Identities = 28/35 (80%), Positives = 30/35 (85%)
Frame = +2
Query: 548 GMVCPTSDLCVGGCNLHATEEGAINIGGLXHFAVD 652
GMVC TSDLCVGGCNL+ATEEG INIGGL FA +
Sbjct: 127 GMVCSTSDLCVGGCNLYATEEGPINIGGLQQFATE 161
Score = 56.8 bits (131), Expect = 1e-07
Identities = 25/59 (42%), Positives = 34/59 (57%)
Frame = +3
Query: 168 MAKLLSKELPDIENLLKLNPTVKPYTNLVPSAQTKKIKXHWKRNADRKCTTCPTLXQEF 344
MA +LSK+ DIE++L LNP + + L ++ K K HWKRN D+ C C L F
Sbjct: 1 MAPVLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENNF 59
>BC064027-1|AAH64027.1| 173|Homo sapiens DPYD protein protein.
Length = 173
Score = 133 bits (322), Expect = 7e-31
Identities = 60/79 (75%), Positives = 65/79 (82%)
Frame = +1
Query: 307 ENVLHVQPXNKNFDDIKHTTLSERGALREAARCLKCADAPCQKSCPTQIDVKSFITSIAN 486
+N + + NFDDIKHTTL ERGALREA RCLKCADAPCQKSCPT +D+KSFITSIAN
Sbjct: 47 KNCFNCEKLENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIAN 106
Query: 487 KNYYGAAKAILSDIPSGLT 543
KNYYGAAK I SD P GLT
Sbjct: 107 KNYYGAAKMIFSDNPLGLT 125
Score = 68.9 bits (161), Expect = 2e-11
Identities = 29/35 (82%), Positives = 31/35 (88%)
Frame = +2
Query: 548 GMVCPTSDLCVGGCNLHATEEGAINIGGLXHFAVD 652
GMVCPTSDLCVGGCNL+ATEEG INIGGL FA +
Sbjct: 127 GMVCPTSDLCVGGCNLYATEEGPINIGGLQQFATE 161
Score = 56.8 bits (131), Expect = 1e-07
Identities = 25/59 (42%), Positives = 34/59 (57%)
Frame = +3
Query: 168 MAKLLSKELPDIENLLKLNPTVKPYTNLVPSAQTKKIKXHWKRNADRKCTTCPTLXQEF 344
MA +LSK+ DIE++L LNP + + L ++ K K HWKRN D+ C C L F
Sbjct: 1 MAPVLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENNF 59
>BC008379-1|AAH08379.1| 173|Homo sapiens DPYD protein protein.
Length = 173
Score = 133 bits (322), Expect = 7e-31
Identities = 60/79 (75%), Positives = 65/79 (82%)
Frame = +1
Query: 307 ENVLHVQPXNKNFDDIKHTTLSERGALREAARCLKCADAPCQKSCPTQIDVKSFITSIAN 486
+N + + NFDDIKHTTL ERGALREA RCLKCADAPCQKSCPT +D+KSFITSIAN
Sbjct: 47 KNCFNCEKLENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIAN 106
Query: 487 KNYYGAAKAILSDIPSGLT 543
KNYYGAAK I SD P GLT
Sbjct: 107 KNYYGAAKMIFSDNPLGLT 125
Score = 68.9 bits (161), Expect = 2e-11
Identities = 29/35 (82%), Positives = 31/35 (88%)
Frame = +2
Query: 548 GMVCPTSDLCVGGCNLHATEEGAINIGGLXHFAVD 652
GMVCPTSDLCVGGCNL+ATEEG INIGGL FA +
Sbjct: 127 GMVCPTSDLCVGGCNLYATEEGPINIGGLQQFATE 161
Score = 56.8 bits (131), Expect = 1e-07
Identities = 25/59 (42%), Positives = 34/59 (57%)
Frame = +3
Query: 168 MAKLLSKELPDIENLLKLNPTVKPYTNLVPSAQTKKIKXHWKRNADRKCTTCPTLXQEF 344
MA +LSK+ DIE++L LNP + + L ++ K K HWKRN D+ C C L F
Sbjct: 1 MAPVLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENNF 59
>AL356457-3|CAH70570.1| 1025|Homo sapiens dihydropyrimidine
dehydrogenase protein.
Length = 1025
Score = 133 bits (322), Expect = 7e-31
Identities = 60/79 (75%), Positives = 65/79 (82%)
Frame = +1
Query: 307 ENVLHVQPXNKNFDDIKHTTLSERGALREAARCLKCADAPCQKSCPTQIDVKSFITSIAN 486
+N + + NFDDIKHTTL ERGALREA RCLKCADAPCQKSCPT +D+KSFITSIAN
Sbjct: 47 KNCFNCEKLENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIAN 106
Query: 487 KNYYGAAKAILSDIPSGLT 543
KNYYGAAK I SD P GLT
Sbjct: 107 KNYYGAAKMIFSDNPLGLT 125
Score = 75.8 bits (178), Expect = 2e-13
Identities = 32/43 (74%), Positives = 35/43 (81%)
Frame = +2
Query: 548 GMVCPTSDLCVGGCNLHATEEGAINIGGLXHFAVDXFMKMGLP 676
GMVCPTSDLCVGGCNL+ATEEG INIGGL FA + F M +P
Sbjct: 127 GMVCPTSDLCVGGCNLYATEEGPINIGGLQQFATEVFKAMSIP 169
Score = 56.0 bits (129), Expect = 2e-07
Identities = 25/59 (42%), Positives = 34/59 (57%)
Frame = +3
Query: 168 MAKLLSKELPDIENLLKLNPTVKPYTNLVPSAQTKKIKXHWKRNADRKCTTCPTLXQEF 344
MA +LSK+ DIE++L LNP + + L ++ K K HWKRN D+ C C L F
Sbjct: 1 MAPVLSKDSADIESILALNPRTQTHATLRSTSAKKLDKKHWKRNPDKNCFNCEKLENNF 59
>AB003063-1|BAA89789.1| 1025|Homo sapiens dihydropyrimidine
dehydrogenase protein.
Length = 1025
Score = 133 bits (322), Expect = 7e-31
Identities = 60/79 (75%), Positives = 65/79 (82%)
Frame = +1
Query: 307 ENVLHVQPXNKNFDDIKHTTLSERGALREAARCLKCADAPCQKSCPTQIDVKSFITSIAN 486
+N + + NFDDIKHTTL ERGALREA RCLKCADAPCQKSCPT +D+KSFITSIAN
Sbjct: 47 KNCFNCEKLENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIAN 106
Query: 487 KNYYGAAKAILSDIPSGLT 543
KNYYGAAK I SD P GLT
Sbjct: 107 KNYYGAAKMIFSDNPLGLT 125
Score = 75.8 bits (178), Expect = 2e-13
Identities = 32/43 (74%), Positives = 35/43 (81%)
Frame = +2
Query: 548 GMVCPTSDLCVGGCNLHATEEGAINIGGLXHFAVDXFMKMGLP 676
GMVCPTSDLCVGGCNL+ATEEG INIGGL FA + F M +P
Sbjct: 127 GMVCPTSDLCVGGCNLYATEEGPINIGGLQQFATEVFKAMSIP 169
Score = 56.8 bits (131), Expect = 1e-07
Identities = 25/59 (42%), Positives = 34/59 (57%)
Frame = +3
Query: 168 MAKLLSKELPDIENLLKLNPTVKPYTNLVPSAQTKKIKXHWKRNADRKCTTCPTLXQEF 344
MA +LSK+ DIE++L LNP + + L ++ K K HWKRN D+ C C L F
Sbjct: 1 MAPVLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENNF 59
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 125,741,916
Number of Sequences: 237096
Number of extensions: 2654308
Number of successful extensions: 4497
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 4313
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4497
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11603768198
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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