Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP18_F_F13
(824 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
S62076-1|AAD13932.1| 529|Homo sapiens HEXA protein. 67 6e-11
M16424-1|AAB00965.1| 529|Homo sapiens HEXA protein. 67 6e-11
M13520-1|AAA51827.1| 490|Homo sapiens HEXA protein. 67 6e-11
BC084537-1|AAH84537.1| 529|Homo sapiens hexosaminidase A (alpha... 67 6e-11
BC018927-1|AAH18927.1| 529|Homo sapiens hexosaminidase A (alpha... 67 6e-11
BC001138-1|AAH01138.2| 409|Homo sapiens HEXA protein protein. 67 6e-11
AK222502-1|BAD96222.1| 529|Homo sapiens hexosaminidase A prepro... 67 6e-11
M23294-1|AAA52645.1| 556|Homo sapiens beta-hexosaminidase beta-... 53 1e-06
M19735-1|AAA68620.1| 544|Homo sapiens beta-hexosaminidase beta-... 53 1e-06
M13519-1|AAA51828.1| 572|Homo sapiens HEXB protein. 53 1e-06
BT009919-1|AAP88921.1| 556|Homo sapiens hexosaminidase B (beta ... 53 1e-06
BC017378-1|AAH17378.1| 556|Homo sapiens hexosaminidase B (beta ... 53 1e-06
AF378118-1|AAM46114.1| 556|Homo sapiens cervical cancer proto-o... 53 1e-06
>S62076-1|AAD13932.1| 529|Homo sapiens HEXA protein.
Length = 529
Score = 67.3 bits (157), Expect = 6e-11
Identities = 29/69 (42%), Positives = 36/69 (52%)
Frame = +2
Query: 614 EVHDFPRYPHRGLLXDTSRHYISMSXXXXXXXXXXXXXXXXFHWHIVDXXXXPYXXXXXX 793
E+ DFPR+PHRGLL DTSRHY+ +S FHWH+VD PY
Sbjct: 160 EIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFP 219
Query: 794 DLXPLGXYH 820
+L G Y+
Sbjct: 220 ELMRKGSYN 228
Score = 40.3 bits (90), Expect = 0.008
Identities = 23/61 (37%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
Frame = +3
Query: 453 EYPHFGMIESYNLTIAADSTLR-SSSIWGILRGLESWTHLFHLSXNRDQLHINKVKFTTF 629
+ P +E+Y LTI D L S ++WG LRGLE+++ L S INK + F
Sbjct: 106 QLPTLESVENYTLTINDDQCLLLSETVWGALRGLETFSQLVWKSA-EGTFFINKTEIEDF 164
Query: 630 P 632
P
Sbjct: 165 P 165
>M16424-1|AAB00965.1| 529|Homo sapiens HEXA protein.
Length = 529
Score = 67.3 bits (157), Expect = 6e-11
Identities = 29/69 (42%), Positives = 36/69 (52%)
Frame = +2
Query: 614 EVHDFPRYPHRGLLXDTSRHYISMSXXXXXXXXXXXXXXXXFHWHIVDXXXXPYXXXXXX 793
E+ DFPR+PHRGLL DTSRHY+ +S FHWH+VD PY
Sbjct: 160 EIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFP 219
Query: 794 DLXPLGXYH 820
+L G Y+
Sbjct: 220 ELMRKGSYN 228
Score = 40.3 bits (90), Expect = 0.008
Identities = 23/61 (37%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
Frame = +3
Query: 453 EYPHFGMIESYNLTIAADSTLR-SSSIWGILRGLESWTHLFHLSXNRDQLHINKVKFTTF 629
+ P +E+Y LTI D L S ++WG LRGLE+++ L S INK + F
Sbjct: 106 QLPTLESVENYTLTINDDQCLLLSETVWGALRGLETFSQLVWKSA-EGTFFINKTEIEDF 164
Query: 630 P 632
P
Sbjct: 165 P 165
>M13520-1|AAA51827.1| 490|Homo sapiens HEXA protein.
Length = 490
Score = 67.3 bits (157), Expect = 6e-11
Identities = 29/69 (42%), Positives = 36/69 (52%)
Frame = +2
Query: 614 EVHDFPRYPHRGLLXDTSRHYISMSXXXXXXXXXXXXXXXXFHWHIVDXXXXPYXXXXXX 793
E+ DFPR+PHRGLL DTSRHY+ +S FHWH+VD PY
Sbjct: 121 EIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFP 180
Query: 794 DLXPLGXYH 820
+L G Y+
Sbjct: 181 ELMRKGSYN 189
Score = 40.3 bits (90), Expect = 0.008
Identities = 23/61 (37%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
Frame = +3
Query: 453 EYPHFGMIESYNLTIAADSTLR-SSSIWGILRGLESWTHLFHLSXNRDQLHINKVKFTTF 629
+ P +E+Y LTI D L S ++WG LRGLE+++ L S INK + F
Sbjct: 67 QLPTLESVENYTLTINDDQCLLLSETVWGALRGLETFSQLVWKSA-EGTFFINKTEIEDF 125
Query: 630 P 632
P
Sbjct: 126 P 126
>BC084537-1|AAH84537.1| 529|Homo sapiens hexosaminidase A (alpha
polypeptide) protein.
Length = 529
Score = 67.3 bits (157), Expect = 6e-11
Identities = 29/69 (42%), Positives = 36/69 (52%)
Frame = +2
Query: 614 EVHDFPRYPHRGLLXDTSRHYISMSXXXXXXXXXXXXXXXXFHWHIVDXXXXPYXXXXXX 793
E+ DFPR+PHRGLL DTSRHY+ +S FHWH+VD PY
Sbjct: 160 EIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFP 219
Query: 794 DLXPLGXYH 820
+L G Y+
Sbjct: 220 ELMRKGSYN 228
Score = 40.3 bits (90), Expect = 0.008
Identities = 23/61 (37%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
Frame = +3
Query: 453 EYPHFGMIESYNLTIAADSTLR-SSSIWGILRGLESWTHLFHLSXNRDQLHINKVKFTTF 629
+ P +E+Y LTI D L S ++WG LRGLE+++ L S INK + F
Sbjct: 106 QLPTLESVENYTLTINDDQCLLLSETVWGALRGLETFSQLVWKSA-EGTFFINKTEIEDF 164
Query: 630 P 632
P
Sbjct: 165 P 165
>BC018927-1|AAH18927.1| 529|Homo sapiens hexosaminidase A (alpha
polypeptide) protein.
Length = 529
Score = 67.3 bits (157), Expect = 6e-11
Identities = 29/69 (42%), Positives = 36/69 (52%)
Frame = +2
Query: 614 EVHDFPRYPHRGLLXDTSRHYISMSXXXXXXXXXXXXXXXXFHWHIVDXXXXPYXXXXXX 793
E+ DFPR+PHRGLL DTSRHY+ +S FHWH+VD PY
Sbjct: 160 EIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFP 219
Query: 794 DLXPLGXYH 820
+L G Y+
Sbjct: 220 ELMRKGSYN 228
Score = 40.3 bits (90), Expect = 0.008
Identities = 23/61 (37%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
Frame = +3
Query: 453 EYPHFGMIESYNLTIAADSTLR-SSSIWGILRGLESWTHLFHLSXNRDQLHINKVKFTTF 629
+ P +E+Y LTI D L S ++WG LRGLE+++ L S INK + F
Sbjct: 106 QLPTLESVENYTLTINDDQCLLLSETVWGALRGLETFSQLVWKSA-EGTFFINKTEIEDF 164
Query: 630 P 632
P
Sbjct: 165 P 165
>BC001138-1|AAH01138.2| 409|Homo sapiens HEXA protein protein.
Length = 409
Score = 67.3 bits (157), Expect = 6e-11
Identities = 29/69 (42%), Positives = 36/69 (52%)
Frame = +2
Query: 614 EVHDFPRYPHRGLLXDTSRHYISMSXXXXXXXXXXXXXXXXFHWHIVDXXXXPYXXXXXX 793
E+ DFPR+PHRGLL DTSRHY+ +S FHWH+VD PY
Sbjct: 40 EIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFP 99
Query: 794 DLXPLGXYH 820
+L G Y+
Sbjct: 100 ELMRKGSYN 108
Score = 31.5 bits (68), Expect = 3.8
Identities = 16/40 (40%), Positives = 22/40 (55%)
Frame = +3
Query: 513 LRSSSIWGILRGLESWTHLFHLSXNRDQLHINKVKFTTFP 632
L S ++WG LRGLE+++ L S INK + FP
Sbjct: 7 LLSETVWGALRGLETFSQLVWKSA-EGTFFINKTEIEDFP 45
>AK222502-1|BAD96222.1| 529|Homo sapiens hexosaminidase A
preproprotein variant protein.
Length = 529
Score = 67.3 bits (157), Expect = 6e-11
Identities = 29/69 (42%), Positives = 36/69 (52%)
Frame = +2
Query: 614 EVHDFPRYPHRGLLXDTSRHYISMSXXXXXXXXXXXXXXXXFHWHIVDXXXXPYXXXXXX 793
E+ DFPR+PHRGLL DTSRHY+ +S FHWH+VD PY
Sbjct: 160 EIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFP 219
Query: 794 DLXPLGXYH 820
+L G Y+
Sbjct: 220 ELMRKGSYN 228
Score = 40.3 bits (90), Expect = 0.008
Identities = 23/61 (37%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
Frame = +3
Query: 453 EYPHFGMIESYNLTIAADSTLR-SSSIWGILRGLESWTHLFHLSXNRDQLHINKVKFTTF 629
+ P +E+Y LTI D L S ++WG LRGLE+++ L S INK + F
Sbjct: 106 QLPTLESVENYTLTINDDQCLLLSETVWGALRGLETFSQLVWKSA-EGTFFINKTEIEDF 164
Query: 630 P 632
P
Sbjct: 165 P 165
>M23294-1|AAA52645.1| 556|Homo sapiens beta-hexosaminidase
beta-subunit protein.
Length = 556
Score = 53.2 bits (122), Expect = 1e-06
Identities = 24/70 (34%), Positives = 31/70 (44%)
Frame = +2
Query: 608 QGEVHDFPRYPHRGLLXDTSRHYISMSXXXXXXXXXXXXXXXXFHWHIVDXXXXPYXXXX 787
+ + D PR+ HRG+L DTSRHY+ + HWHIVD PY
Sbjct: 191 ESTIIDSPRFSHRGILIDTSRHYLPVKIILKTLDAMAFNKFNVLHWHIVDDQSFPYQSIT 250
Query: 788 XXDLXPLGXY 817
+L G Y
Sbjct: 251 FPELSNKGSY 260
Score = 34.3 bits (75), Expect = 0.54
Identities = 14/43 (32%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
Frame = +3
Query: 450 EEYPHFGMIESYNLTIAAD-STLRSSSIWGILRGLESWTHLFH 575
+ +P+ ESY L + + L+++ +WG LRGLE+++ L +
Sbjct: 138 DAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVY 180
>M19735-1|AAA68620.1| 544|Homo sapiens beta-hexosaminidase
beta-subunit protein.
Length = 544
Score = 53.2 bits (122), Expect = 1e-06
Identities = 24/70 (34%), Positives = 31/70 (44%)
Frame = +2
Query: 608 QGEVHDFPRYPHRGLLXDTSRHYISMSXXXXXXXXXXXXXXXXFHWHIVDXXXXPYXXXX 787
+ + D PR+ HRG+L DTSRHY+ + HWHIVD PY
Sbjct: 179 ESTIIDSPRFSHRGILIDTSRHYLPVKIILKTLDAMAFNKFNVLHWHIVDDQSFPYQSIT 238
Query: 788 XXDLXPLGXY 817
+L G Y
Sbjct: 239 FPELSNKGSY 248
Score = 34.3 bits (75), Expect = 0.54
Identities = 14/43 (32%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
Frame = +3
Query: 450 EEYPHFGMIESYNLTIAAD-STLRSSSIWGILRGLESWTHLFH 575
+ +P+ ESY L + + L+++ +WG LRGLE+++ L +
Sbjct: 126 DAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVY 168
>M13519-1|AAA51828.1| 572|Homo sapiens HEXB protein.
Length = 572
Score = 53.2 bits (122), Expect = 1e-06
Identities = 24/70 (34%), Positives = 31/70 (44%)
Frame = +2
Query: 608 QGEVHDFPRYPHRGLLXDTSRHYISMSXXXXXXXXXXXXXXXXFHWHIVDXXXXPYXXXX 787
+ + D PR+ HRG+L DTSRHY+ + HWHIVD PY
Sbjct: 207 ESTIIDSPRFSHRGILIDTSRHYLPVKIILKTLDAMAFNKFNVLHWHIVDDQSFPYQSIT 266
Query: 788 XXDLXPLGXY 817
+L G Y
Sbjct: 267 FPELSNKGSY 276
Score = 34.3 bits (75), Expect = 0.54
Identities = 14/43 (32%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
Frame = +3
Query: 450 EEYPHFGMIESYNLTIAAD-STLRSSSIWGILRGLESWTHLFH 575
+ +P+ ESY L + + L+++ +WG LRGLE+++ L +
Sbjct: 154 DAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVY 196
>BT009919-1|AAP88921.1| 556|Homo sapiens hexosaminidase B (beta
polypeptide) protein.
Length = 556
Score = 53.2 bits (122), Expect = 1e-06
Identities = 24/70 (34%), Positives = 31/70 (44%)
Frame = +2
Query: 608 QGEVHDFPRYPHRGLLXDTSRHYISMSXXXXXXXXXXXXXXXXFHWHIVDXXXXPYXXXX 787
+ + D PR+ HRG+L DTSRHY+ + HWHIVD PY
Sbjct: 191 ESTIIDSPRFSHRGILIDTSRHYLPVKIILKTLDAMAFNKFNVLHWHIVDDQSFPYQSIT 250
Query: 788 XXDLXPLGXY 817
+L G Y
Sbjct: 251 FPELSNKGSY 260
Score = 34.3 bits (75), Expect = 0.54
Identities = 14/43 (32%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
Frame = +3
Query: 450 EEYPHFGMIESYNLTIAAD-STLRSSSIWGILRGLESWTHLFH 575
+ +P+ ESY L + + L+++ +WG LRGLE+++ L +
Sbjct: 138 DAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVY 180
>BC017378-1|AAH17378.1| 556|Homo sapiens hexosaminidase B (beta
polypeptide) protein.
Length = 556
Score = 53.2 bits (122), Expect = 1e-06
Identities = 24/70 (34%), Positives = 31/70 (44%)
Frame = +2
Query: 608 QGEVHDFPRYPHRGLLXDTSRHYISMSXXXXXXXXXXXXXXXXFHWHIVDXXXXPYXXXX 787
+ + D PR+ HRG+L DTSRHY+ + HWHIVD PY
Sbjct: 191 ESTIIDSPRFSHRGILIDTSRHYLPVKIILKTLDAMAFNKFNVLHWHIVDDQSFPYQSIT 250
Query: 788 XXDLXPLGXY 817
+L G Y
Sbjct: 251 FPELSNKGSY 260
Score = 34.3 bits (75), Expect = 0.54
Identities = 14/43 (32%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
Frame = +3
Query: 450 EEYPHFGMIESYNLTIAAD-STLRSSSIWGILRGLESWTHLFH 575
+ +P+ ESY L + + L+++ +WG LRGLE+++ L +
Sbjct: 138 DAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVY 180
>AF378118-1|AAM46114.1| 556|Homo sapiens cervical cancer
proto-oncogene 7 protein.
Length = 556
Score = 53.2 bits (122), Expect = 1e-06
Identities = 24/70 (34%), Positives = 31/70 (44%)
Frame = +2
Query: 608 QGEVHDFPRYPHRGLLXDTSRHYISMSXXXXXXXXXXXXXXXXFHWHIVDXXXXPYXXXX 787
+ + D PR+ HRG+L DTSRHY+ + HWHIVD PY
Sbjct: 191 ESTIIDSPRFSHRGILIDTSRHYLPVKIILKTLDAMAFNKFNVLHWHIVDDQSFPYQSIT 250
Query: 788 XXDLXPLGXY 817
+L G Y
Sbjct: 251 FPELSNKGSY 260
Score = 34.3 bits (75), Expect = 0.54
Identities = 14/43 (32%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
Frame = +3
Query: 450 EEYPHFGMIESYNLTIAAD-STLRSSSIWGILRGLESWTHLFH 575
+ +P+ ESY L + + L+++ +WG LRGLE+++ L +
Sbjct: 138 DAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVY 180
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 97,605,740
Number of Sequences: 237096
Number of extensions: 1955374
Number of successful extensions: 3714
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 3557
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3701
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10315140830
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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