Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP17_F_J11
(874 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 118 2e-26
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 118 4e-26
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 118 4e-26
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 118 4e-26
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 118 4e-26
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 118 4e-26
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 118 4e-26
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 118 4e-26
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 118 4e-26
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 118 4e-26
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 118 4e-26
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 118 4e-26
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 118 4e-26
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 118 4e-26
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 112 2e-24
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 109 1e-23
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 109 1e-23
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 109 1e-23
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 109 1e-23
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 109 1e-23
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 109 1e-23
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 109 1e-23
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 109 1e-23
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 109 1e-23
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 109 1e-23
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 109 1e-23
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 109 1e-23
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 109 1e-23
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 109 1e-23
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 109 1e-23
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 109 1e-23
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 109 1e-23
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 109 1e-23
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 109 1e-23
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 109 1e-23
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 109 1e-23
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 109 1e-23
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 108 3e-23
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 108 3e-23
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 108 3e-23
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 108 3e-23
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 108 3e-23
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 108 3e-23
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 108 3e-23
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 108 3e-23
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 104 4e-22
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 104 5e-22
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 103 6e-22
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 102 1e-21
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 102 1e-21
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 102 1e-21
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 102 1e-21
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 102 1e-21
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 102 1e-21
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 102 1e-21
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 102 2e-21
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 100 6e-21
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 99 1e-20
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 99 1e-20
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 99 1e-20
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 99 1e-20
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 99 1e-20
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 99 1e-20
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 97 7e-20
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 97 1e-19
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 97 1e-19
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 97 1e-19
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 97 1e-19
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 97 1e-19
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 97 1e-19
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 96 1e-19
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 95 4e-19
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 94 5e-19
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 94 5e-19
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 94 5e-19
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 94 5e-19
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 94 5e-19
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 93 1e-18
AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 93 1e-18
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 93 1e-18
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 90 8e-18
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 87 6e-17
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 87 6e-17
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 87 6e-17
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 87 6e-17
BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 87 8e-17
BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 87 8e-17
AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 87 8e-17
AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto red... 84 6e-16
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 76 1e-13
AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthas... 34 0.77
AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens ... 30 9.5
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 118 bits (285), Expect = 2e-26
Identities = 74/218 (33%), Positives = 114/218 (52%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LNNG P LG G W ++T+A K+ AID+GYRHID AH+Y+ E EVG
Sbjct: 7 LNNGAKMPILGLGTW----KSPPGQVTEAVKV------AIDVGYRHIDCAHVYQNENEVG 56
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMS- 588
I +K+++ VVKRE+ F+ +K+W +H++ V+ A + L L L+Y+DL L+ WP+
Sbjct: 57 VAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPIGF 116
Query: 589 --------ISQEG--VDENIDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+ + G V + + L+TW + G + H E + +
Sbjct: 117 KPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGL 176
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + L Q +L+ YCQSKG+VV AYSP G
Sbjct: 177 KYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 118 bits (283), Expect = 4e-26
Identities = 74/218 (33%), Positives = 113/218 (51%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LNNG P LG G W ++T+A K+ AID+GYRHID AH+Y+ E EVG
Sbjct: 7 LNNGAKMPILGLGTW----KSPPGQVTEAVKV------AIDVGYRHIDCAHVYQNENEVG 56
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMS- 588
I +K+++ VVKRE+ F+ +K+W +H++ V+ A + L L L+Y+DL L+ WP
Sbjct: 57 VAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGF 116
Query: 589 --------ISQEG--VDENIDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+ + G V + + L+TW + G + H E + +
Sbjct: 117 KPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGL 176
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + L Q +L+ YCQSKG+VV AYSP G
Sbjct: 177 KYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 118 bits (283), Expect = 4e-26
Identities = 74/218 (33%), Positives = 113/218 (51%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LNNG P LG G W ++T+A K+ AID+GYRHID AH+Y+ E EVG
Sbjct: 7 LNNGAKMPILGLGTW----KSPPGQVTEAVKV------AIDVGYRHIDCAHVYQNENEVG 56
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMS- 588
I +K+++ VVKRE+ F+ +K+W +H++ V+ A + L L L+Y+DL L+ WP
Sbjct: 57 VAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGF 116
Query: 589 --------ISQEG--VDENIDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+ + G V + + L+TW + G + H E + +
Sbjct: 117 KPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGL 176
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + L Q +L+ YCQSKG+VV AYSP G
Sbjct: 177 KYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 118 bits (283), Expect = 4e-26
Identities = 74/218 (33%), Positives = 113/218 (51%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LNNG P LG G W ++T+A K+ AID+GYRHID AH+Y+ E EVG
Sbjct: 7 LNNGAKMPILGLGTW----KSPPGQVTEAVKV------AIDVGYRHIDCAHVYQNENEVG 56
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMS- 588
I +K+++ VVKRE+ F+ +K+W +H++ V+ A + L L L+Y+DL L+ WP
Sbjct: 57 VAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGF 116
Query: 589 --------ISQEG--VDENIDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+ + G V + + L+TW + G + H E + +
Sbjct: 117 KPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGL 176
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + L Q +L+ YCQSKG+VV AYSP G
Sbjct: 177 KYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 118 bits (283), Expect = 4e-26
Identities = 74/218 (33%), Positives = 113/218 (51%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LNNG P LG G W ++T+A K+ AID+GYRHID AH+Y+ E EVG
Sbjct: 7 LNNGAKMPILGLGTW----KSPPGQVTEAVKV------AIDVGYRHIDCAHVYQNENEVG 56
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMS- 588
I +K+++ VVKRE+ F+ +K+W +H++ V+ A + L L L+Y+DL L+ WP
Sbjct: 57 VAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGF 116
Query: 589 --------ISQEG--VDENIDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+ + G V + + L+TW + G + H E + +
Sbjct: 117 KPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGL 176
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + L Q +L+ YCQSKG+VV AYSP G
Sbjct: 177 KYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 118 bits (283), Expect = 4e-26
Identities = 74/218 (33%), Positives = 113/218 (51%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LNNG P LG G W ++T+A K+ AID+GYRHID AH+Y+ E EVG
Sbjct: 7 LNNGAKMPILGLGTW----KSPPGQVTEAVKV------AIDVGYRHIDCAHVYQNENEVG 56
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMS- 588
I +K+++ VVKRE+ F+ +K+W +H++ V+ A + L L L+Y+DL L+ WP
Sbjct: 57 VAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGF 116
Query: 589 --------ISQEG--VDENIDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+ + G V + + L+TW + G + H E + +
Sbjct: 117 KPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGL 176
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + L Q +L+ YCQSKG+VV AYSP G
Sbjct: 177 KYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 118 bits (283), Expect = 4e-26
Identities = 74/218 (33%), Positives = 113/218 (51%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LNNG P LG G W ++T+A K+ AID+GYRHID AH+Y+ E EVG
Sbjct: 7 LNNGAKMPILGLGTW----KSPPGQVTEAVKV------AIDVGYRHIDCAHVYQNENEVG 56
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMS- 588
I +K+++ VVKRE+ F+ +K+W +H++ V+ A + L L L+Y+DL L+ WP
Sbjct: 57 VAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGF 116
Query: 589 --------ISQEG--VDENIDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+ + G V + + L+TW + G + H E + +
Sbjct: 117 KPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGL 176
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + L Q +L+ YCQSKG+VV AYSP G
Sbjct: 177 KYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 118 bits (283), Expect = 4e-26
Identities = 74/218 (33%), Positives = 113/218 (51%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LNNG P LG G W ++T+A K+ AID+GYRHID AH+Y+ E EVG
Sbjct: 7 LNNGAKMPILGLGTW----KSPPGQVTEAVKV------AIDVGYRHIDCAHVYQNENEVG 56
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMS- 588
I +K+++ VVKRE+ F+ +K+W +H++ V+ A + L L L+Y+DL L+ WP
Sbjct: 57 VAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGF 116
Query: 589 --------ISQEG--VDENIDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+ + G V + + L+TW + G + H E + +
Sbjct: 117 RPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILSKPGL 176
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + L Q +L+ YCQSKG+VV AYSP G
Sbjct: 177 KYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 118 bits (283), Expect = 4e-26
Identities = 74/218 (33%), Positives = 113/218 (51%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LNNG P LG G W ++T+A K+ AID+GYRHID AH+Y+ E EVG
Sbjct: 7 LNNGAKMPILGLGTW----KSPPGQVTEAVKV------AIDVGYRHIDCAHVYQNENEVG 56
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMS- 588
I +K+++ VVKRE+ F+ +K+W +H++ V+ A + L L L+Y+DL L+ WP
Sbjct: 57 VAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGF 116
Query: 589 --------ISQEG--VDENIDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+ + G V + + L+TW + G + H E + +
Sbjct: 117 KPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGL 176
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + L Q +L+ YCQSKG+VV AYSP G
Sbjct: 177 KYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 118 bits (283), Expect = 4e-26
Identities = 74/218 (33%), Positives = 113/218 (51%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LNNG P LG G W ++T+A K+ AID+GYRHID AH+Y+ E EVG
Sbjct: 7 LNNGAKMPILGLGTW----KSPPGQVTEAVKV------AIDVGYRHIDCAHVYQNENEVG 56
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMS- 588
I +K+++ VVKRE+ F+ +K+W +H++ V+ A + L L L+Y+DL L+ WP
Sbjct: 57 VAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGF 116
Query: 589 --------ISQEG--VDENIDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+ + G V + + L+TW + G + H E + +
Sbjct: 117 KPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGL 176
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + L Q +L+ YCQSKG+VV AYSP G
Sbjct: 177 KYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 118 bits (283), Expect = 4e-26
Identities = 74/218 (33%), Positives = 113/218 (51%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LNNG P LG G W ++T+A K+ AID+GYRHID AH+Y+ E EVG
Sbjct: 7 LNNGAKMPILGLGTW----KSPPGQVTEAVKV------AIDVGYRHIDCAHVYQNENEVG 56
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMS- 588
I +K+++ VVKRE+ F+ +K+W +H++ V+ A + L L L+Y+DL L+ WP
Sbjct: 57 VAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGF 116
Query: 589 --------ISQEG--VDENIDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+ + G V + + L+TW + G + H E + +
Sbjct: 117 KPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGL 176
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + L Q +L+ YCQSKG+VV AYSP G
Sbjct: 177 KYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 118 bits (283), Expect = 4e-26
Identities = 74/218 (33%), Positives = 113/218 (51%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LNNG P LG G W ++T+A K+ AID+GYRHID AH+Y+ E EVG
Sbjct: 7 LNNGAKMPILGLGTW----KSPPGQVTEAVKV------AIDVGYRHIDCAHVYQNENEVG 56
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMS- 588
I +K+++ VVKRE+ F+ +K+W +H++ V+ A + L L L+Y+DL L+ WP
Sbjct: 57 VAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGF 116
Query: 589 --------ISQEG--VDENIDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+ + G V + + L+TW + G + H E + +
Sbjct: 117 KPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGL 176
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + L Q +L+ YCQSKG+VV AYSP G
Sbjct: 177 KYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 118 bits (283), Expect = 4e-26
Identities = 74/218 (33%), Positives = 113/218 (51%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LNNG P LG G W ++T+A K+ AID+GYRHID AH+Y+ E EVG
Sbjct: 7 LNNGAKMPILGLGTW----KSPPGQVTEAVKV------AIDVGYRHIDCAHVYQNENEVG 56
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMS- 588
I +K+++ VVKRE+ F+ +K+W +H++ V+ A + L L L+Y+DL L+ WP
Sbjct: 57 VAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGF 116
Query: 589 --------ISQEG--VDENIDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+ + G V + + L+TW + G + H E + +
Sbjct: 117 KPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGL 176
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + L Q +L+ YCQSKG+VV AYSP G
Sbjct: 177 KYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 118 bits (283), Expect = 4e-26
Identities = 74/218 (33%), Positives = 113/218 (51%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LNNG P LG G W ++T+A K+ AID+GYRHID AH+Y+ E EVG
Sbjct: 4 LNNGAKMPILGLGTW----KSPPGQVTEAVKV------AIDVGYRHIDCAHVYQNENEVG 53
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMS- 588
I +K+++ VVKRE+ F+ +K+W +H++ V+ A + L L L+Y+DL L+ WP
Sbjct: 54 VAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGF 113
Query: 589 --------ISQEG--VDENIDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+ + G V + + L+TW + G + H E + +
Sbjct: 114 KPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGL 173
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + L Q +L+ YCQSKG+VV AYSP G
Sbjct: 174 KYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 211
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 112 bits (269), Expect = 2e-24
Identities = 73/218 (33%), Positives = 112/218 (51%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LNNG P LG G W ++T+A K+ AID+GYRHID AH+Y+ E EVG
Sbjct: 7 LNNGAKMPILGLGTW----KSPPGQVTEAVKV------AIDVGYRHIDCAHVYQNENEVG 56
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWP--- 582
I +K+++ VVKRE+ F+ +K+W +H++ V+ A + L L L+Y+DL L+ WP
Sbjct: 57 VAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGF 116
Query: 583 ------MSISQEG--VDENIDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+ + G V + + L+T + G + H E + +
Sbjct: 117 KPGKEFFPLDESGNVVPSDTNILDTRAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGL 176
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + L Q +L+ YCQSKG+VV AYSP G
Sbjct: 177 KYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
Score = 33.9 bits (74), Expect = 0.77
Identities = 18/41 (43%), Positives = 27/41 (65%), Gaps = 2/41 (4%)
Frame = +2
Query: 647 EEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
EE++ GL ++IG+SNFN Q++ +L + AVNQIE
Sbjct: 146 EELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIE 186
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 109 bits (263), Expect = 1e-23
Identities = 72/218 (33%), Positives = 113/218 (51%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ ++ L+ A+ AI+ G+ HID+AH+Y E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPA------EVPKSKALE-AVKLAIEAGFHHIDSAHVYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W + H+ V A+ L+ L L+YVDL L+ +P+S+
Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122
Query: 592 --SQEGV--DEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+E + DEN +D TW + G + HR E + +
Sbjct: 123 KPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + Q +L+D+C+SK +V+VAYS G
Sbjct: 183 KYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 109 bits (263), Expect = 1e-23
Identities = 73/220 (33%), Positives = 114/220 (51%), Gaps = 15/220 (6%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ ++ L+ A+ AI+ G+ HID+AH+Y E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPA------EVPKSKALE-AVKLAIEAGFHHIDSAHVYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W + H+ V A+ L+ L L+YVDL L+ +P+S+
Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122
Query: 592 --SQEGV--DEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+E + DEN +D TW + G + HR E + +
Sbjct: 123 KPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNE--P 180
Query: 739 AXRRQPDRDXLN----LGQXELVDYCQSKGVVVVAYSPFG 846
+ +P + + Q +L+D+C+SK +V+VAYS G
Sbjct: 181 GLKYEPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 109 bits (263), Expect = 1e-23
Identities = 73/220 (33%), Positives = 113/220 (51%), Gaps = 15/220 (6%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ ++ L+ A+ AI+ GY HID+AH+Y E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPA------EVPKSKALE-AVKLAIEAGYHHIDSAHVYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W + H+ V A+ L+ L L+Y DL L+ +P+S+
Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYADLYLIHFPVSV 122
Query: 592 --SQEGV--DEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+E + DEN +D TW + G + HR E + +
Sbjct: 123 KPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNE--P 180
Query: 739 AXRRQPDRDXLN----LGQXELVDYCQSKGVVVVAYSPFG 846
+ +P + + Q +L+D+C+SK +V+VAYS G
Sbjct: 181 GLKYEPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 109 bits (263), Expect = 1e-23
Identities = 72/218 (33%), Positives = 113/218 (51%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ ++ L+ A+ AI+ G+ HID+AH+Y E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPA------EVPKSKALE-AVKLAIEAGFHHIDSAHVYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W + H+ V A+ L+ L L+YVDL L+ +P+S+
Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122
Query: 592 --SQEGV--DEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+E + DEN +D TW + G + HR E + +
Sbjct: 123 KPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + Q +L+D+C+SK +V+VAYS G
Sbjct: 183 KYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 109 bits (263), Expect = 1e-23
Identities = 72/218 (33%), Positives = 113/218 (51%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ ++ L+ A+ AI+ G+ HID+AH+Y E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPA------EVPKSKALE-AVKLAIEAGFHHIDSAHVYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W + H+ V A+ L+ L L+YVDL L+ +P+S+
Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122
Query: 592 --SQEGV--DEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+E + DEN +D TW + G + HR E + +
Sbjct: 123 KPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + Q +L+D+C+SK +V+VAYS G
Sbjct: 183 KYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 109 bits (263), Expect = 1e-23
Identities = 72/218 (33%), Positives = 113/218 (51%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ ++ L+ A+ AI+ G+ HID+AH+Y E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPA------EVPKSKALE-AVKLAIEAGFHHIDSAHVYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W + H+ V A+ L+ L L+YVDL L+ +P+S+
Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122
Query: 592 --SQEGV--DEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+E + DEN +D TW + G + HR E + +
Sbjct: 123 KPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + Q +L+D+C+SK +V+VAYS G
Sbjct: 183 KYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 109 bits (263), Expect = 1e-23
Identities = 72/218 (33%), Positives = 113/218 (51%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ ++ L+ A+ AI+ G+ HID+AH+Y E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPA------EVPKSKALE-AVKLAIEAGFHHIDSAHVYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W + H+ V A+ L+ L L+YVDL L+ +P+S+
Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122
Query: 592 --SQEGV--DEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+E + DEN +D TW + G + HR E + +
Sbjct: 123 KPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + Q +L+D+C+SK +V+VAYS G
Sbjct: 183 KYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 109 bits (263), Expect = 1e-23
Identities = 72/218 (33%), Positives = 113/218 (51%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ ++ L+ A+ AI+ G+ HID+AH+Y E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPA------EVPKSKALE-AVKLAIEAGFHHIDSAHVYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W + H+ V A+ L+ L L+YVDL L+ +P+S+
Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122
Query: 592 --SQEGV--DEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+E + DEN +D TW + G + HR E + +
Sbjct: 123 KPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + Q +L+D+C+SK +V+VAYS G
Sbjct: 183 KYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 109 bits (263), Expect = 1e-23
Identities = 72/218 (33%), Positives = 113/218 (51%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ ++ L+ A+ AI+ G+ HID+AH+Y E +VG
Sbjct: 23 LNDGHFMPVLGFGTYAPA------EVPKSKALE-AVKLAIEAGFHHIDSAHVYNNEEQVG 75
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W + H+ V A+ L+ L L+YVDL L+ +P+S+
Sbjct: 76 LAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 135
Query: 592 --SQEGV--DEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+E + DEN +D TW + G + HR E + +
Sbjct: 136 KPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGL 195
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + Q +L+D+C+SK +V+VAYS G
Sbjct: 196 KYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 233
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 109 bits (263), Expect = 1e-23
Identities = 72/218 (33%), Positives = 113/218 (51%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ ++ L+ A+ AI+ G+ HID+AH+Y E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPA------EVPKSKALE-AVKLAIEAGFHHIDSAHVYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W + H+ V A+ L+ L L+YVDL L+ +P+S+
Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122
Query: 592 --SQEGV--DEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+E + DEN +D TW + G + HR E + +
Sbjct: 123 KPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + Q +L+D+C+SK +V+VAYS G
Sbjct: 183 KYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 109 bits (263), Expect = 1e-23
Identities = 72/218 (33%), Positives = 113/218 (51%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ ++ L+ A+ AI+ G+ HID+AH+Y E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPA------EVPKSKALE-AVKLAIEAGFHHIDSAHVYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W + H+ V A+ L+ L L+YVDL L+ +P+S+
Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122
Query: 592 --SQEGV--DEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+E + DEN +D TW + G + HR E + +
Sbjct: 123 KPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + Q +L+D+C+SK +V+VAYS G
Sbjct: 183 KYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 109 bits (263), Expect = 1e-23
Identities = 72/218 (33%), Positives = 113/218 (51%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ ++ L+ A+ AI+ G+ HID+AH+Y E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPA------EVPKSKALE-AVKLAIEAGFHHIDSAHVYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W + H+ V A+ L+ L L+YVDL L+ +P+S+
Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122
Query: 592 --SQEGV--DEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+E + DEN +D TW + G + HR E + +
Sbjct: 123 KPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + Q +L+D+C+SK +V+VAYS G
Sbjct: 183 KYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 109 bits (262), Expect = 1e-23
Identities = 74/218 (33%), Positives = 112/218 (51%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ ++ L+ A AI+ G+RHID+AHLY E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPA------EVPKSKALE-ATKLAIEAGFRHIDSAHLYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W + H+ V A+ L+ L L+YVDL L+ +P+S+
Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122
Query: 592 --SQEGV--DEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+E + DEN +D TW V G + R E + +
Sbjct: 123 KPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + Q +L+D+C+SK +V+VAYS G
Sbjct: 183 KYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
Score = 31.9 bits (69), Expect = 3.1
Identities = 19/52 (36%), Positives = 27/52 (51%), Gaps = 2/52 (3%)
Frame = +2
Query: 614 ISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
+ TW E E+ GL +SIGVSNFN Q++ +L + NQ+E
Sbjct: 144 LCATW---EAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 109 bits (262), Expect = 1e-23
Identities = 74/218 (33%), Positives = 112/218 (51%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ ++ L+ A AI+ G+RHID+AHLY E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPA------EVPKSKALE-ATKLAIEAGFRHIDSAHLYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W + H+ V A+ L+ L L+YVDL L+ +P+S+
Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122
Query: 592 --SQEGV--DEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+E + DEN +D TW V G + R E + +
Sbjct: 123 KPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + Q +L+D+C+SK +V+VAYS G
Sbjct: 183 KYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
Score = 31.9 bits (69), Expect = 3.1
Identities = 19/52 (36%), Positives = 27/52 (51%), Gaps = 2/52 (3%)
Frame = +2
Query: 614 ISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
+ TW E E+ GL +SIGVSNFN Q++ +L + NQ+E
Sbjct: 144 LCATW---EAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 109 bits (262), Expect = 1e-23
Identities = 74/218 (33%), Positives = 112/218 (51%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ ++ L+ A AI+ G+RHID+AHLY E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPA------EVPKSKALE-ATKLAIEAGFRHIDSAHLYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W + H+ V A+ L+ L L+YVDL L+ +P+S+
Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122
Query: 592 --SQEGV--DEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+E + DEN +D TW V G + R E + +
Sbjct: 123 KPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + Q +L+D+C+SK +V+VAYS G
Sbjct: 183 KYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
Score = 31.9 bits (69), Expect = 3.1
Identities = 19/52 (36%), Positives = 27/52 (51%), Gaps = 2/52 (3%)
Frame = +2
Query: 614 ISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
+ TW E E+ GL +SIGVSNFN Q++ +L + NQ+E
Sbjct: 144 LCATW---EAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 109 bits (262), Expect = 1e-23
Identities = 74/218 (33%), Positives = 112/218 (51%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ ++ L+ A AI+ G+RHID+AHLY E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPA------EVPKSKALE-ATKLAIEAGFRHIDSAHLYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W + H+ V A+ L+ L L+YVDL L+ +P+S+
Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122
Query: 592 --SQEGV--DEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+E + DEN +D TW V G + R E + +
Sbjct: 123 KPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + Q +L+D+C+SK +V+VAYS G
Sbjct: 183 KYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
Score = 31.9 bits (69), Expect = 3.1
Identities = 19/52 (36%), Positives = 27/52 (51%), Gaps = 2/52 (3%)
Frame = +2
Query: 614 ISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
+ TW E E+ GL +SIGVSNFN Q++ +L + NQ+E
Sbjct: 144 LCATW---EAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 109 bits (262), Expect = 1e-23
Identities = 74/218 (33%), Positives = 112/218 (51%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ ++ L+ A AI+ G+RHID+AHLY E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPA------EVPKSKALE-ATKLAIEAGFRHIDSAHLYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W + H+ V A+ L+ L L+YVDL L+ +P+S+
Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122
Query: 592 --SQEGV--DEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+E + DEN +D TW V G + R E + +
Sbjct: 123 KPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + Q +L+D+C+SK +V+VAYS G
Sbjct: 183 KYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
Score = 31.9 bits (69), Expect = 3.1
Identities = 19/52 (36%), Positives = 27/52 (51%), Gaps = 2/52 (3%)
Frame = +2
Query: 614 ISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
+ TW E E+ GL +SIGVSNFN Q++ +L + NQ+E
Sbjct: 144 LCATW---EAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 109 bits (262), Expect = 1e-23
Identities = 74/218 (33%), Positives = 112/218 (51%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ ++ L+ A AI+ G+RHID+AHLY E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPA------EVPKSKALE-ATKLAIEAGFRHIDSAHLYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W + H+ V A+ L+ L L+YVDL L+ +P+S+
Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122
Query: 592 --SQEGV--DEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+E + DEN +D TW V G + R E + +
Sbjct: 123 KPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + Q +L+D+C+SK +V+VAYS G
Sbjct: 183 KYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
Score = 31.9 bits (69), Expect = 3.1
Identities = 19/52 (36%), Positives = 27/52 (51%), Gaps = 2/52 (3%)
Frame = +2
Query: 614 ISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
+ TW E E+ GL +SIGVSNFN Q++ +L + NQ+E
Sbjct: 144 LCATW---EAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 109 bits (262), Expect = 1e-23
Identities = 74/218 (33%), Positives = 112/218 (51%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ ++ L+ A AI+ G+RHID+AHLY E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPA------EVPKSKALE-ATKLAIEAGFRHIDSAHLYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W + H+ V A+ L+ L L+YVDL L+ +P+S+
Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122
Query: 592 --SQEGV--DEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+E + DEN +D TW V G + R E + +
Sbjct: 123 KPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + Q +L+D+C+SK +V+VAYS G
Sbjct: 183 KYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
Score = 31.9 bits (69), Expect = 3.1
Identities = 19/52 (36%), Positives = 27/52 (51%), Gaps = 2/52 (3%)
Frame = +2
Query: 614 ISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
+ TW E E+ GL +SIGVSNFN Q++ +L + NQ+E
Sbjct: 144 LCATW---EAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 109 bits (262), Expect = 1e-23
Identities = 74/218 (33%), Positives = 112/218 (51%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ ++ L+ A AI+ G+RHID+AHLY E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPA------EVPKSKALE-ATKLAIEAGFRHIDSAHLYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W + H+ V A+ L+ L L+YVDL L+ +P+S+
Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122
Query: 592 --SQEGV--DEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+E + DEN +D TW V G + R E + +
Sbjct: 123 KPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + Q +L+D+C+SK +V+VAYS G
Sbjct: 183 KYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
Score = 31.9 bits (69), Expect = 3.1
Identities = 19/52 (36%), Positives = 27/52 (51%), Gaps = 2/52 (3%)
Frame = +2
Query: 614 ISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
+ TW E E+ GL +SIGVSNFN Q++ +L + NQ+E
Sbjct: 144 LCATW---EAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 109 bits (262), Expect = 1e-23
Identities = 74/218 (33%), Positives = 112/218 (51%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ ++ L+ A AI+ G+RHID+AHLY E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPA------EVPKSKALE-ATKLAIEAGFRHIDSAHLYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W + H+ V A+ L+ L L+YVDL L+ +P+S+
Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122
Query: 592 --SQEGV--DEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+E + DEN +D TW V G + R E + +
Sbjct: 123 KPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + Q +L+D+C+SK +V+VAYS G
Sbjct: 183 KYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
Score = 31.9 bits (69), Expect = 3.1
Identities = 19/52 (36%), Positives = 27/52 (51%), Gaps = 2/52 (3%)
Frame = +2
Query: 614 ISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
+ TW E E+ GL +SIGVSNFN Q++ +L + NQ+E
Sbjct: 144 LCATW---EAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 109 bits (262), Expect = 1e-23
Identities = 74/218 (33%), Positives = 112/218 (51%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ ++ L+ A AI+ G+RHID+AHLY E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPA------EVPKSKALE-ATKLAIEAGFRHIDSAHLYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W + H+ V A+ L+ L L+YVDL L+ +P+S+
Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSV 122
Query: 592 --SQEGV--DEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+E + DEN +D TW V G + R E + +
Sbjct: 123 KPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + Q +L+D+C+SK +V+VAYS G
Sbjct: 183 KYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
Score = 31.9 bits (69), Expect = 3.1
Identities = 19/52 (36%), Positives = 27/52 (51%), Gaps = 2/52 (3%)
Frame = +2
Query: 614 ISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
+ TW E E+ GL +SIGVSNFN Q++ +L + NQ+E
Sbjct: 144 LCATW---EAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 108 bits (259), Expect = 3e-23
Identities = 68/217 (31%), Positives = 105/217 (48%), Gaps = 12/217 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
L+ G P +G G W ++ +++ A+ YA+ +GYRHID A +Y EPE+G
Sbjct: 8 LHTGQKMPLIGLGTWK----------SEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIG 57
Query: 412 EVINKKIKDG-VVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMS 588
E + + + G V RE+ FVT+K+W+ H DVE A+R L L LEY+DL L+ WP +
Sbjct: 58 EALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYA 117
Query: 589 ISQ------EGVD-----ENIDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLX 735
+ + D ++ Y ETW+ + G Q R +++
Sbjct: 118 FERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVAS 177
Query: 736 XAXRRQPDRDXLNLGQXELVDYCQSKGVVVVAYSPFG 846
L Q EL+ +CQ++G+ V AYSP G
Sbjct: 178 VRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLG 214
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 108 bits (259), Expect = 3e-23
Identities = 68/217 (31%), Positives = 105/217 (48%), Gaps = 12/217 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
L+ G P +G G W ++ +++ A+ YA+ +GYRHID A +Y EPE+G
Sbjct: 8 LHTGQKMPLIGLGTWK----------SEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIG 57
Query: 412 EVINKKIKDG-VVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMS 588
E + + + G V RE+ FVT+K+W+ H DVE A+R L L LEY+DL L+ WP +
Sbjct: 58 EALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYA 117
Query: 589 ISQ------EGVD-----ENIDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLX 735
+ + D ++ Y ETW+ + G Q R +++
Sbjct: 118 FERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVAS 177
Query: 736 XAXRRQPDRDXLNLGQXELVDYCQSKGVVVVAYSPFG 846
L Q EL+ +CQ++G+ V AYSP G
Sbjct: 178 VRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLG 214
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 108 bits (259), Expect = 3e-23
Identities = 68/217 (31%), Positives = 105/217 (48%), Gaps = 12/217 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
L+ G P +G G W ++ +++ A+ YA+ +GYRHID A +Y EPE+G
Sbjct: 8 LHTGQKMPLIGLGTWK----------SEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIG 57
Query: 412 EVINKKIKDG-VVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMS 588
E + + + G V RE+ FVT+K+W+ H DVE A+R L L LEY+DL L+ WP +
Sbjct: 58 EALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYA 117
Query: 589 ISQ------EGVD-----ENIDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLX 735
+ + D ++ Y ETW+ + G Q R +++
Sbjct: 118 FERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVAS 177
Query: 736 XAXRRQPDRDXLNLGQXELVDYCQSKGVVVVAYSPFG 846
L Q EL+ +CQ++G+ V AYSP G
Sbjct: 178 VRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLG 214
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 108 bits (259), Expect = 3e-23
Identities = 68/217 (31%), Positives = 105/217 (48%), Gaps = 12/217 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
L+ G P +G G W ++ +++ A+ YA+ +GYRHID A +Y EPE+G
Sbjct: 8 LHTGQKMPLIGLGTWK----------SEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIG 57
Query: 412 EVINKKIKDG-VVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMS 588
E + + + G V RE+ FVT+K+W+ H DVE A+R L L LEY+DL L+ WP +
Sbjct: 58 EALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYA 117
Query: 589 ISQ------EGVD-----ENIDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLX 735
+ + D ++ Y ETW+ + G Q R +++
Sbjct: 118 FERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVAS 177
Query: 736 XAXRRQPDRDXLNLGQXELVDYCQSKGVVVVAYSPFG 846
L Q EL+ +CQ++G+ V AYSP G
Sbjct: 178 VRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLG 214
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 108 bits (259), Expect = 3e-23
Identities = 68/217 (31%), Positives = 105/217 (48%), Gaps = 12/217 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
L+ G P +G G W ++ +++ A+ YA+ +GYRHID A +Y EPE+G
Sbjct: 8 LHTGQKMPLIGLGTWK----------SEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIG 57
Query: 412 EVINKKIKDG-VVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMS 588
E + + + G V RE+ FVT+K+W+ H DVE A+R L L LEY+DL L+ WP +
Sbjct: 58 EALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYA 117
Query: 589 ISQ------EGVD-----ENIDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLX 735
+ + D ++ Y ETW+ + G Q R +++
Sbjct: 118 FERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVAS 177
Query: 736 XAXRRQPDRDXLNLGQXELVDYCQSKGVVVVAYSPFG 846
L Q EL+ +CQ++G+ V AYSP G
Sbjct: 178 VRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLG 214
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 108 bits (259), Expect = 3e-23
Identities = 68/217 (31%), Positives = 105/217 (48%), Gaps = 12/217 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
L+ G P +G G W ++ +++ A+ YA+ +GYRHID A +Y EPE+G
Sbjct: 8 LHTGQKMPLIGLGTWK----------SEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIG 57
Query: 412 EVINKKIKDG-VVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMS 588
E + + + G V RE+ FVT+K+W+ H DVE A+R L L LEY+DL L+ WP +
Sbjct: 58 EALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYA 117
Query: 589 ISQ------EGVD-----ENIDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLX 735
+ + D ++ Y ETW+ + G Q R +++
Sbjct: 118 FERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVAS 177
Query: 736 XAXRRQPDRDXLNLGQXELVDYCQSKGVVVVAYSPFG 846
L Q EL+ +CQ++G+ V AYSP G
Sbjct: 178 VRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLG 214
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 108 bits (259), Expect = 3e-23
Identities = 68/217 (31%), Positives = 105/217 (48%), Gaps = 12/217 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
L+ G P +G G W ++ +++ A+ YA+ +GYRHID A +Y EPE+G
Sbjct: 8 LHTGQKMPLIGLGTWK----------SEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIG 57
Query: 412 EVINKKIKDG-VVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMS 588
E + + + G V RE+ FVT+K+W+ H DVE A+R L L LEY+DL L+ WP +
Sbjct: 58 EALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYA 117
Query: 589 ISQ------EGVD-----ENIDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLX 735
+ + D ++ Y ETW+ + G Q R +++
Sbjct: 118 FERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVAS 177
Query: 736 XAXRRQPDRDXLNLGQXELVDYCQSKGVVVVAYSPFG 846
L Q EL+ +CQ++G+ V AYSP G
Sbjct: 178 VRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLG 214
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 108 bits (259), Expect = 3e-23
Identities = 68/217 (31%), Positives = 105/217 (48%), Gaps = 12/217 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
L+ G P +G G W ++ +++ A+ YA+ +GYRHID A +Y EPE+G
Sbjct: 8 LHTGQKMPLIGLGTWK----------SEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIG 57
Query: 412 EVINKKIKDG-VVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMS 588
E + + + G V RE+ FVT+K+W+ H DVE A+R L L LEY+DL L+ WP +
Sbjct: 58 EALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYA 117
Query: 589 ISQ------EGVD-----ENIDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLX 735
+ + D ++ Y ETW+ + G Q R +++
Sbjct: 118 FERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVAS 177
Query: 736 XAXRRQPDRDXLNLGQXELVDYCQSKGVVVVAYSPFG 846
L Q EL+ +CQ++G+ V AYSP G
Sbjct: 178 VRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLG 214
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 104 bits (250), Expect = 4e-22
Identities = 69/203 (33%), Positives = 104/203 (51%), Gaps = 13/203 (6%)
Frame = +1
Query: 277 LGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVGEVINKKIKDGVVKRE 456
LG E+ ++ L+ A AI+ G+RHID+AHLY E +VG I KI DG VKRE
Sbjct: 2 LGFGTYAPAEVPKSKALE-ATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKRE 60
Query: 457 DXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI--SQEGV--DEN--- 615
D F T+K+W + H+ V A+ L+ L L+YVDL L+ +P+S+ +E + DEN
Sbjct: 61 DIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKI 120
Query: 616 ----IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXXAXRRQPDRDXLN--L 777
+D TW V G + R E + + + ++ +
Sbjct: 121 LFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYF 180
Query: 778 GQXELVDYCQSKGVVVVAYSPFG 846
Q +L+D+C+SK +V+VAYS G
Sbjct: 181 NQRKLLDFCKSKDIVLVAYSALG 203
Score = 31.9 bits (69), Expect = 3.1
Identities = 19/52 (36%), Positives = 27/52 (51%), Gaps = 2/52 (3%)
Frame = +2
Query: 614 ISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
+ TW E E+ GL +SIGVSNFN Q++ +L + NQ+E
Sbjct: 127 LCATW---EAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 175
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 104 bits (249), Expect = 5e-22
Identities = 70/218 (32%), Positives = 108/218 (49%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ ++ L+ A AI+ G+RHID+AHLY E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPA------EVPKSKALE-ATKLAIEAGFRHIDSAHLYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
+ KI DG VKRED F T+K+W + H+ V A+ L++ L+YVDL L+ PMS+
Sbjct: 63 LAVRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKKAQLDYVDLYLIHSPMSL 122
Query: 592 SQ----EGVDEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
DEN +D TW + G + R E + +
Sbjct: 123 KPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + + +L+D+C+SK +V+VAYS G
Sbjct: 183 KYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
Score = 34.3 bits (75), Expect = 0.58
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Frame = +2
Query: 614 ISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
+ TTW E E+ GL +SIGVSNFN Q++ +L + NQ+E
Sbjct: 144 LCTTW---EAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 103 bits (248), Expect = 6e-22
Identities = 72/220 (32%), Positives = 111/220 (50%), Gaps = 13/220 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ ++ L+ A AI+ G+RHID+AHLY E +VG
Sbjct: 7 LNDGHFMPVLGFGTYAPA------EVPKSKALE-ATKLAIEAGFRHIDSAHLYNNEEQVG 59
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W + H+ A+ L+ L L+YVDL L+ +P+S+
Sbjct: 60 LAIRSKIADGSVKREDIFYTSKLWCNSHRPELDRPALERSLKNLQLDYVDLYLIHFPVSV 119
Query: 592 --SQEGV--DEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
+E + DEN +D TW V + T E + +
Sbjct: 120 KPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAELAKSIGVSNFNRSTLEMILNKPGL 179
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFGXM 852
+ ++ + Q +L+D+C+SK +V+VAYS G +
Sbjct: 180 QVKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSL 219
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 102 bits (245), Expect = 1e-21
Identities = 70/218 (32%), Positives = 107/218 (49%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ ++ L+ AI+ G+RHID+AHLY E +VG
Sbjct: 12 LNDGHFMPVLGFGTYAPP------EVPRSKALE-VTKLAIEAGFRHIDSAHLYNNEEQVG 64
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W H+ V A+ + L++ L+YVDL L+ PMS+
Sbjct: 65 LAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSL 124
Query: 592 SQ----EGVDEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
DEN +D TW + G + R E + +
Sbjct: 125 KPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGL 184
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + + +L+D+C+SK +V+VAYS G
Sbjct: 185 KYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 222
Score = 34.3 bits (75), Expect = 0.58
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Frame = +2
Query: 614 ISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
+ TTW E E+ GL +SIGVSNFN Q++ +L + NQ+E
Sbjct: 146 LCTTW---EAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 194
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 102 bits (245), Expect = 1e-21
Identities = 70/218 (32%), Positives = 107/218 (49%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ ++ L+ AI+ G+RHID+AHLY E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPP------EVPRSKALE-VTKLAIEAGFRHIDSAHLYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W H+ V A+ + L++ L+YVDL L+ PMS+
Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSL 122
Query: 592 SQ----EGVDEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
DEN +D TW + G + R E + +
Sbjct: 123 KPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + + +L+D+C+SK +V+VAYS G
Sbjct: 183 KYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
Score = 34.3 bits (75), Expect = 0.58
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Frame = +2
Query: 614 ISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
+ TTW E E+ GL +SIGVSNFN Q++ +L + NQ+E
Sbjct: 144 LCTTW---EAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 102 bits (245), Expect = 1e-21
Identities = 70/218 (32%), Positives = 107/218 (49%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ ++ L+ AI+ G+RHID+AHLY E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPP------EVPRSKALE-VTKLAIEAGFRHIDSAHLYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W H+ V A+ + L++ L+YVDL L+ PMS+
Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSL 122
Query: 592 SQ----EGVDEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
DEN +D TW + G + R E + +
Sbjct: 123 KPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + + +L+D+C+SK +V+VAYS G
Sbjct: 183 KYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
Score = 34.3 bits (75), Expect = 0.58
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Frame = +2
Query: 614 ISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
+ TTW E E+ GL +SIGVSNFN Q++ +L + NQ+E
Sbjct: 144 LCTTW---EAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 102 bits (245), Expect = 1e-21
Identities = 70/218 (32%), Positives = 107/218 (49%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ ++ L+ AI+ G+RHID+AHLY E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPP------EVPRSKALE-VTKLAIEAGFRHIDSAHLYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W H+ V A+ + L++ L+YVDL L+ PMS+
Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSL 122
Query: 592 SQ----EGVDEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
DEN +D TW + G + R E + +
Sbjct: 123 KPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + + +L+D+C+SK +V+VAYS G
Sbjct: 183 KYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
Score = 34.3 bits (75), Expect = 0.58
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Frame = +2
Query: 614 ISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
+ TTW E E+ GL +SIGVSNFN Q++ +L + NQ+E
Sbjct: 144 LCTTW---EAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 102 bits (245), Expect = 1e-21
Identities = 70/218 (32%), Positives = 107/218 (49%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ ++ L+ AI+ G+RHID+AHLY E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPP------EVPRSKALE-VTKLAIEAGFRHIDSAHLYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W H+ V A+ + L++ L+YVDL L+ PMS+
Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSL 122
Query: 592 SQ----EGVDEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
DEN +D TW + G + R E + +
Sbjct: 123 KPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + + +L+D+C+SK +V+VAYS G
Sbjct: 183 KYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
Score = 34.3 bits (75), Expect = 0.58
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Frame = +2
Query: 614 ISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
+ TTW E E+ GL +SIGVSNFN Q++ +L + NQ+E
Sbjct: 144 LCTTW---EAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 102 bits (245), Expect = 1e-21
Identities = 70/218 (32%), Positives = 107/218 (49%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ ++ L+ AI+ G+RHID+AHLY E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPP------EVPRSKALE-VTKLAIEAGFRHIDSAHLYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W H+ V A+ + L++ L+YVDL L+ PMS+
Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSL 122
Query: 592 SQ----EGVDEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
DEN +D TW + G + R E + +
Sbjct: 123 KPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + + +L+D+C+SK +V+VAYS G
Sbjct: 183 KYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
Score = 34.3 bits (75), Expect = 0.58
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Frame = +2
Query: 614 ISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
+ TTW E E+ GL +SIGVSNFN Q++ +L + NQ+E
Sbjct: 144 LCTTW---EAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 102 bits (245), Expect = 1e-21
Identities = 70/218 (32%), Positives = 107/218 (49%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ ++ L+ AI+ G+RHID+AHLY E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPP------EVPRSKALE-VTKLAIEAGFRHIDSAHLYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W H+ V A+ + L++ L+YVDL L+ PMS+
Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSL 122
Query: 592 SQ----EGVDEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
DEN +D TW + G + R E + +
Sbjct: 123 KPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + + +L+D+C+SK +V+VAYS G
Sbjct: 183 KYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
Score = 34.3 bits (75), Expect = 0.58
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Frame = +2
Query: 614 ISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
+ TTW E E+ GL +SIGVSNFN Q++ +L + NQ+E
Sbjct: 144 LCTTW---EAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 102 bits (244), Expect = 2e-21
Identities = 70/218 (32%), Positives = 108/218 (49%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ ++ L+ + AI+ G+RHID+AHLY E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPP------EVPRSKALEVS-KLAIEAGFRHIDSAHLYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W H+ V A+ + L++ L+YVDL L+ PMS+
Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWSTSHRPELVRPALENSLKKAQLDYVDLYLIHSPMSL 122
Query: 592 SQ----EGVDEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
DEN +D TW + G + R E + +
Sbjct: 123 KPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + + +L+D+C+SK +V+VAYS G
Sbjct: 183 KYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
Score = 34.3 bits (75), Expect = 0.58
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Frame = +2
Query: 614 ISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
+ TTW E E+ GL +SIGVSNFN Q++ +L + NQ+E
Sbjct: 144 LCTTW---EAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 192
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 100 bits (240), Expect = 6e-21
Identities = 69/218 (31%), Positives = 107/218 (49%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ ++ L+ AI+ G+RHID+AHLY E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPP------EVPRSKALE-VTKLAIEAGFRHIDSAHLYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG V+RED F T+K+W H+ V A+ + L++ L+YVDL L+ PMS+
Sbjct: 63 LAIRSKIADGSVEREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSL 122
Query: 592 SQ----EGVDEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
DEN +D TW + G + R E + +
Sbjct: 123 KPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + + +L+D+C+SK +V+VAYS G
Sbjct: 183 KYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
Score = 33.5 bits (73), Expect = 1.0
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Frame = +2
Query: 614 ISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
+ TTW E E+ GL +SIGVSNFN Q++ +L + NQ+E
Sbjct: 144 LCTTW---EAMEKCKDAGLAKSIGVSNFNRRQLEIILNKPGLKYKPVCNQVE 192
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 99 bits (238), Expect = 1e-20
Identities = 58/188 (30%), Positives = 92/188 (48%), Gaps = 13/188 (6%)
Frame = +1
Query: 322 KLQDALSYAIDIGYRHIDTAHLYRVEPEVGEVINKKIKDGVVKREDXFVTTKVWHHHHKQ 501
K+++A+ AID GYRHID A++Y+ E EVGE I +KI++ VKRED F+ +K+W ++
Sbjct: 27 KVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFER 86
Query: 502 ADVEVAVRDCLRRLNLEYVDLVLVXWPMSISQ-----------EGVDENIDYLETWRGV* 648
V A L+ L L Y+D+ L+ WP + +L+ W +
Sbjct: 87 PLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAME 146
Query: 649 GGPQXGTXQVHRRVQLQHRTDEEVTXQLXXAXRRQPDRDXLN--LGQXELVDYCQSKGVV 822
G + H E++ + + ++ + L Q +L+ YC SKG+
Sbjct: 147 ELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGIT 206
Query: 823 VVAYSPFG 846
V AYSP G
Sbjct: 207 VTAYSPLG 214
Score = 31.9 bits (69), Expect = 3.1
Identities = 16/44 (36%), Positives = 27/44 (61%), Gaps = 2/44 (4%)
Frame = +2
Query: 638 EGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
E EE++ GL +++GVSNF+ Q+++LL + NQ+E
Sbjct: 143 EAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVE 186
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 99 bits (238), Expect = 1e-20
Identities = 69/218 (31%), Positives = 106/218 (48%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ ++ L+ AI+ G+RHID+AHLY E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPP------EVPRSKALE-VTKLAIEAGFRHIDSAHLYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG V RED F T+K+W H+ V A+ + L++ L+YVDL L+ PMS+
Sbjct: 63 LAIRSKIADGSVMREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSL 122
Query: 592 SQ----EGVDEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
DEN +D TW + G + R E + +
Sbjct: 123 KPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + + +L+D+C+SK +V+VAYS G
Sbjct: 183 KYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
Score = 33.5 bits (73), Expect = 1.0
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Frame = +2
Query: 614 ISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
+ TTW E E+ GL +SIGVSNFN Q++ +L + NQ+E
Sbjct: 144 LCTTW---EAMEKCKDAGLAKSIGVSNFNRRQLEIILNKPGLKYKPVCNQVE 192
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 99 bits (238), Expect = 1e-20
Identities = 58/188 (30%), Positives = 92/188 (48%), Gaps = 13/188 (6%)
Frame = +1
Query: 322 KLQDALSYAIDIGYRHIDTAHLYRVEPEVGEVINKKIKDGVVKREDXFVTTKVWHHHHKQ 501
K+++A+ AID GYRHID A++Y+ E EVGE I +KI++ VKRED F+ +K+W ++
Sbjct: 27 KVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFER 86
Query: 502 ADVEVAVRDCLRRLNLEYVDLVLVXWPMSISQ-----------EGVDENIDYLETWRGV* 648
V A L+ L L Y+D+ L+ WP + +L+ W +
Sbjct: 87 PLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAME 146
Query: 649 GGPQXGTXQVHRRVQLQHRTDEEVTXQLXXAXRRQPDRDXLN--LGQXELVDYCQSKGVV 822
G + H E++ + + ++ + L Q +L+ YC SKG+
Sbjct: 147 ELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGIT 206
Query: 823 VVAYSPFG 846
V AYSP G
Sbjct: 207 VTAYSPLG 214
Score = 31.9 bits (69), Expect = 3.1
Identities = 16/44 (36%), Positives = 27/44 (61%), Gaps = 2/44 (4%)
Frame = +2
Query: 638 EGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
E EE++ GL +++GVSNF+ Q+++LL + NQ+E
Sbjct: 143 EAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVE 186
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 99 bits (238), Expect = 1e-20
Identities = 58/188 (30%), Positives = 92/188 (48%), Gaps = 13/188 (6%)
Frame = +1
Query: 322 KLQDALSYAIDIGYRHIDTAHLYRVEPEVGEVINKKIKDGVVKREDXFVTTKVWHHHHKQ 501
K+++A+ AID GYRHID A++Y+ E EVGE I +KI++ VKRED F+ +K+W ++
Sbjct: 27 KVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFER 86
Query: 502 ADVEVAVRDCLRRLNLEYVDLVLVXWPMSISQ-----------EGVDENIDYLETWRGV* 648
V A L+ L L Y+D+ L+ WP + +L+ W +
Sbjct: 87 PLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAME 146
Query: 649 GGPQXGTXQVHRRVQLQHRTDEEVTXQLXXAXRRQPDRDXLN--LGQXELVDYCQSKGVV 822
G + H E++ + + ++ + L Q +L+ YC SKG+
Sbjct: 147 ELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGIT 206
Query: 823 VVAYSPFG 846
V AYSP G
Sbjct: 207 VTAYSPLG 214
Score = 31.9 bits (69), Expect = 3.1
Identities = 16/44 (36%), Positives = 27/44 (61%), Gaps = 2/44 (4%)
Frame = +2
Query: 638 EGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
E EE++ GL +++GVSNF+ Q+++LL + NQ+E
Sbjct: 143 EAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVE 186
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 99 bits (238), Expect = 1e-20
Identities = 58/188 (30%), Positives = 92/188 (48%), Gaps = 13/188 (6%)
Frame = +1
Query: 322 KLQDALSYAIDIGYRHIDTAHLYRVEPEVGEVINKKIKDGVVKREDXFVTTKVWHHHHKQ 501
K+++A+ AID GYRHID A++Y+ E EVGE I +KI++ VKRED F+ +K+W ++
Sbjct: 27 KVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFER 86
Query: 502 ADVEVAVRDCLRRLNLEYVDLVLVXWPMSISQ-----------EGVDENIDYLETWRGV* 648
V A L+ L L Y+D+ L+ WP + +L+ W +
Sbjct: 87 PLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAME 146
Query: 649 GGPQXGTXQVHRRVQLQHRTDEEVTXQLXXAXRRQPDRDXLN--LGQXELVDYCQSKGVV 822
G + H E++ + + ++ + L Q +L+ YC SKG+
Sbjct: 147 ELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGIT 206
Query: 823 VVAYSPFG 846
V AYSP G
Sbjct: 207 VTAYSPLG 214
Score = 31.9 bits (69), Expect = 3.1
Identities = 16/44 (36%), Positives = 27/44 (61%), Gaps = 2/44 (4%)
Frame = +2
Query: 638 EGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
E EE++ GL +++GVSNF+ Q+++LL + NQ+E
Sbjct: 143 EAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVE 186
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 99 bits (238), Expect = 1e-20
Identities = 58/188 (30%), Positives = 92/188 (48%), Gaps = 13/188 (6%)
Frame = +1
Query: 322 KLQDALSYAIDIGYRHIDTAHLYRVEPEVGEVINKKIKDGVVKREDXFVTTKVWHHHHKQ 501
K+++A+ AID GYRHID A++Y+ E EVGE I +KI++ VKRED F+ +K+W ++
Sbjct: 27 KVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFER 86
Query: 502 ADVEVAVRDCLRRLNLEYVDLVLVXWPMSISQ-----------EGVDENIDYLETWRGV* 648
V A L+ L L Y+D+ L+ WP + +L+ W +
Sbjct: 87 PLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAME 146
Query: 649 GGPQXGTXQVHRRVQLQHRTDEEVTXQLXXAXRRQPDRDXLN--LGQXELVDYCQSKGVV 822
G + H E++ + + ++ + L Q +L+ YC SKG+
Sbjct: 147 ELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGIT 206
Query: 823 VVAYSPFG 846
V AYSP G
Sbjct: 207 VTAYSPLG 214
Score = 31.9 bits (69), Expect = 3.1
Identities = 16/44 (36%), Positives = 27/44 (61%), Gaps = 2/44 (4%)
Frame = +2
Query: 638 EGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
E EE++ GL +++GVSNF+ Q+++LL + NQ+E
Sbjct: 143 EAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVE 186
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 97.1 bits (231), Expect = 7e-20
Identities = 57/188 (30%), Positives = 91/188 (48%), Gaps = 13/188 (6%)
Frame = +1
Query: 322 KLQDALSYAIDIGYRHIDTAHLYRVEPEVGEVINKKIKDGVVKREDXFVTTKVWHHHHKQ 501
K+++A+ AID GYRHID A++Y+ E EVGE I +KI++ VKRED F+ +K+W ++
Sbjct: 27 KVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIASKLWPTFFER 86
Query: 502 ADVEVAVRDCLRRLNLEYVDLVLVXWPMSISQ-----------EGVDENIDYLETWRGV* 648
V A L+ L Y+D+ L+ WP + +L+ W +
Sbjct: 87 PLVRKAFEKTLKDPKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAME 146
Query: 649 GGPQXGTXQVHRRVQLQHRTDEEVTXQLXXAXRRQPDRDXLN--LGQXELVDYCQSKGVV 822
G + H E++ + + ++ + L Q +L+ YC SKG+
Sbjct: 147 ELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGIT 206
Query: 823 VVAYSPFG 846
V AYSP G
Sbjct: 207 VTAYSPLG 214
Score = 31.9 bits (69), Expect = 3.1
Identities = 16/44 (36%), Positives = 27/44 (61%), Gaps = 2/44 (4%)
Frame = +2
Query: 638 EGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
E EE++ GL +++GVSNF+ Q+++LL + NQ+E
Sbjct: 143 EAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVE 186
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 96.7 bits (230), Expect = 1e-19
Identities = 45/88 (51%), Positives = 58/88 (65%)
Frame = +1
Query: 322 KLQDALSYAIDIGYRHIDTAHLYRVEPEVGEVINKKIKDGVVKREDXFVTTKVWHHHHKQ 501
K+ +A+ AID GYRH D A+ Y E EVG I KIK+G V+RED F+ TK+W HK+
Sbjct: 18 KVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKK 77
Query: 502 ADVEVAVRDCLRRLNLEYVDLVLVXWPM 585
+ VE A R L+ L L Y+DL L+ WPM
Sbjct: 78 SLVETACRKSLKALKLNYLDLYLIHWPM 105
Score = 38.3 bits (85), Expect = 0.036
Identities = 23/54 (42%), Positives = 31/54 (57%), Gaps = 2/54 (3%)
Frame = +2
Query: 608 TKISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
T TW E E+++ GL ++IGVSNFN EQ++RLL + NQIE
Sbjct: 146 TDFLDTW---EAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIE 196
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 96.7 bits (230), Expect = 1e-19
Identities = 45/88 (51%), Positives = 58/88 (65%)
Frame = +1
Query: 322 KLQDALSYAIDIGYRHIDTAHLYRVEPEVGEVINKKIKDGVVKREDXFVTTKVWHHHHKQ 501
K+ +A+ AID GYRH D A+ Y E EVG I KIK+G V+RED F+ TK+W HK+
Sbjct: 18 KVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKK 77
Query: 502 ADVEVAVRDCLRRLNLEYVDLVLVXWPM 585
+ VE A R L+ L L Y+DL L+ WPM
Sbjct: 78 SLVETACRKSLKALKLNYLDLYLIHWPM 105
Score = 38.3 bits (85), Expect = 0.036
Identities = 23/54 (42%), Positives = 31/54 (57%), Gaps = 2/54 (3%)
Frame = +2
Query: 608 TKISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
T TW E E+++ GL ++IGVSNFN EQ++RLL + NQIE
Sbjct: 146 TDFLDTW---EAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIE 196
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 96.7 bits (230), Expect = 1e-19
Identities = 45/88 (51%), Positives = 58/88 (65%)
Frame = +1
Query: 322 KLQDALSYAIDIGYRHIDTAHLYRVEPEVGEVINKKIKDGVVKREDXFVTTKVWHHHHKQ 501
K+ +A+ AID GYRH D A+ Y E EVG I KIK+G V+RED F+ TK+W HK+
Sbjct: 18 KVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKK 77
Query: 502 ADVEVAVRDCLRRLNLEYVDLVLVXWPM 585
+ VE A R L+ L L Y+DL L+ WPM
Sbjct: 78 SLVETACRKSLKALKLNYLDLYLIHWPM 105
Score = 38.3 bits (85), Expect = 0.036
Identities = 23/54 (42%), Positives = 31/54 (57%), Gaps = 2/54 (3%)
Frame = +2
Query: 608 TKISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
T TW E E+++ GL ++IGVSNFN EQ++RLL + NQIE
Sbjct: 146 TDFLDTW---EAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIE 196
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 96.7 bits (230), Expect = 1e-19
Identities = 45/88 (51%), Positives = 58/88 (65%)
Frame = +1
Query: 322 KLQDALSYAIDIGYRHIDTAHLYRVEPEVGEVINKKIKDGVVKREDXFVTTKVWHHHHKQ 501
K+ +A+ AID GYRH D A+ Y E EVG I KIK+G V+RED F+ TK+W HK+
Sbjct: 18 KVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKK 77
Query: 502 ADVEVAVRDCLRRLNLEYVDLVLVXWPM 585
+ VE A R L+ L L Y+DL L+ WPM
Sbjct: 78 SLVETACRKSLKALKLNYLDLYLIHWPM 105
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 96.7 bits (230), Expect = 1e-19
Identities = 45/88 (51%), Positives = 58/88 (65%)
Frame = +1
Query: 322 KLQDALSYAIDIGYRHIDTAHLYRVEPEVGEVINKKIKDGVVKREDXFVTTKVWHHHHKQ 501
K+ +A+ AID GYRH D A+ Y E EVG I KIK+G V+RED F+ TK+W HK+
Sbjct: 18 KVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKK 77
Query: 502 ADVEVAVRDCLRRLNLEYVDLVLVXWPM 585
+ VE A R L+ L L Y+DL L+ WPM
Sbjct: 78 SLVETACRKSLKALKLNYLDLYLIHWPM 105
Score = 37.5 bits (83), Expect = 0.063
Identities = 19/39 (48%), Positives = 26/39 (66%)
Frame = +2
Query: 608 TKISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLL 724
T TW E E+++ GL ++IGVSNFN EQ++RLL
Sbjct: 146 TDFLDTW---EAMEDLVITGLVKNIGVSNFNHEQLERLL 181
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 96.7 bits (230), Expect = 1e-19
Identities = 45/88 (51%), Positives = 58/88 (65%)
Frame = +1
Query: 322 KLQDALSYAIDIGYRHIDTAHLYRVEPEVGEVINKKIKDGVVKREDXFVTTKVWHHHHKQ 501
K+ +A+ AID GYRH D A+ Y E EVG I KIK+G V+RED F+ TK+W HK+
Sbjct: 18 KVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKK 77
Query: 502 ADVEVAVRDCLRRLNLEYVDLVLVXWPM 585
+ VE A R L+ L L Y+DL L+ WPM
Sbjct: 78 SLVETACRKSLKALKLNYLDLYLIHWPM 105
Score = 37.5 bits (83), Expect = 0.063
Identities = 19/39 (48%), Positives = 26/39 (66%)
Frame = +2
Query: 608 TKISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLL 724
T TW E E+++ GL ++IGVSNFN EQ++RLL
Sbjct: 146 TDFLDTW---EAMEDLVITGLVKNIGVSNFNHEQLERLL 181
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 96.3 bits (229), Expect = 1e-19
Identities = 69/218 (31%), Positives = 109/218 (50%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ R ++ AI+ G+RHID+A+LY E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPP------EVPRNRAVE-VTKLAIEAGFRHIDSAYLYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W + V+ A+ L++L L+YVDL L+ +PM++
Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMAL 122
Query: 592 SQEGV----DEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
DEN +D TW + G + +R E + +
Sbjct: 123 KPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + L Q +L+D+C+SK +V+VA+S G
Sbjct: 183 KYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 220
Score = 33.9 bits (74), Expect = 0.77
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Frame = +2
Query: 614 ISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
+S TW E E+ GL +SIGVSNFN Q++ +L + NQ+E
Sbjct: 144 LSATW---EVMEKCKDAGLAKSIGVSNFNYRQLEMILNKPGLKYKPVCNQVE 192
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 94.7 bits (225), Expect = 4e-19
Identities = 69/218 (31%), Positives = 108/218 (49%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ R ++ AI+ G+RHID+A+LY E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPP------EVPRNRAVE-VTKLAIEAGFRHIDSAYLYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W + V+ A+ L++L L+YVDL L+ +PM++
Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMAL 122
Query: 592 SQEGV----DEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
DEN +D TW + G + R E + +
Sbjct: 123 KPGETPLPKDENGKVIFDTVDLCATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + L Q +L+D+C+SK +V+VA+S G
Sbjct: 183 KYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 220
Score = 31.9 bits (69), Expect = 3.1
Identities = 19/52 (36%), Positives = 27/52 (51%), Gaps = 2/52 (3%)
Frame = +2
Query: 614 ISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
+ TW E E+ GL +SIGVSNFN Q++ +L + NQ+E
Sbjct: 144 LCATW---EVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVE 192
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 94.3 bits (224), Expect = 5e-19
Identities = 69/218 (31%), Positives = 108/218 (49%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ R ++ AI+ G+RHID+A+LY E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPP------EVPRNRAVE-VTKLAIEAGFRHIDSAYLYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W + V+ A+ L++L L+YVDL L+ +PM++
Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMAL 122
Query: 592 SQEGV----DEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
DEN +D TW + G + R E + +
Sbjct: 123 KPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + L Q +L+D+C+SK +V+VA+S G
Sbjct: 183 KYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 220
Score = 33.9 bits (74), Expect = 0.77
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Frame = +2
Query: 614 ISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
+S TW E E+ GL +SIGVSNFN Q++ +L + NQ+E
Sbjct: 144 LSATW---EVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVE 192
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 94.3 bits (224), Expect = 5e-19
Identities = 69/218 (31%), Positives = 108/218 (49%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ R ++ AI+ G+RHID+A+LY E +VG
Sbjct: 8 LNDGHFMPVLGFGTYAPP------EVPRNRAVE-VTKLAIEAGFRHIDSAYLYNNEEQVG 60
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W + V+ A+ L++L L+YVDL L+ +PM++
Sbjct: 61 LAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMAL 120
Query: 592 SQEGV----DEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
DEN +D TW + G + R E + +
Sbjct: 121 KPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGL 180
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + L Q +L+D+C+SK +V+VA+S G
Sbjct: 181 KYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 218
Score = 33.9 bits (74), Expect = 0.77
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Frame = +2
Query: 614 ISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
+S TW E E+ GL +SIGVSNFN Q++ +L + NQ+E
Sbjct: 142 LSATW---EVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVE 190
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 94.3 bits (224), Expect = 5e-19
Identities = 69/218 (31%), Positives = 108/218 (49%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ R ++ AI+ G+RHID+A+LY E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPP------EVPRNRAVE-VTKLAIEAGFRHIDSAYLYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W + V+ A+ L++L L+YVDL L+ +PM++
Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMAL 122
Query: 592 SQEGV----DEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
DEN +D TW + G + R E + +
Sbjct: 123 KPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + L Q +L+D+C+SK +V+VA+S G
Sbjct: 183 KYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 220
Score = 33.9 bits (74), Expect = 0.77
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Frame = +2
Query: 614 ISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
+S TW E E+ GL +SIGVSNFN Q++ +L + NQ+E
Sbjct: 144 LSATW---EVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVE 192
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 94.3 bits (224), Expect = 5e-19
Identities = 69/218 (31%), Positives = 108/218 (49%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ R ++ AI+ G+RHID+A+LY E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPP------EVPRNRAVE-VTKLAIEAGFRHIDSAYLYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W + V+ A+ L++L L+YVDL L+ +PM++
Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMAL 122
Query: 592 SQEGV----DEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
DEN +D TW + G + R E + +
Sbjct: 123 KPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + L Q +L+D+C+SK +V+VA+S G
Sbjct: 183 KYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 220
Score = 33.9 bits (74), Expect = 0.77
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Frame = +2
Query: 614 ISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
+S TW E E+ GL +SIGVSNFN Q++ +L + NQ+E
Sbjct: 144 LSATW---EVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVE 192
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 94.3 bits (224), Expect = 5e-19
Identities = 69/218 (31%), Positives = 108/218 (49%), Gaps = 13/218 (5%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + E+ R ++ AI+ G+RHID+A+LY E +VG
Sbjct: 10 LNDGHFMPVLGFGTYAPP------EVPRNRAVE-VTKLAIEAGFRHIDSAYLYNNEEQVG 62
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
I KI DG VKRED F T+K+W + V+ A+ L++L L+YVDL L+ +PM++
Sbjct: 63 LAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMAL 122
Query: 592 SQEGV----DEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXX 738
DEN +D TW + G + R E + +
Sbjct: 123 KPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGL 182
Query: 739 AXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + L Q +L+D+C+SK +V+VA+S G
Sbjct: 183 KYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 220
Score = 33.9 bits (74), Expect = 0.77
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Frame = +2
Query: 614 ISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
+S TW E E+ GL +SIGVSNFN Q++ +L + NQ+E
Sbjct: 144 LSATW---EVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVE 192
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 93.1 bits (221), Expect = 1e-18
Identities = 65/205 (31%), Positives = 105/205 (51%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + + T + +A AID+G+RHID+A+LY+ E EVG
Sbjct: 13 LNDGPFMPVLGFGTYAP-------DHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVG 65
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
+ I +KI DG VKRE+ F T K+W + V A+ L++L +YVDL ++ P ++
Sbjct: 66 QAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAM 125
Query: 592 SQEGVDENIDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXXAXRRQPDRDXL 771
Q G E + + G T ++ +L+ ++ + L
Sbjct: 126 KQPG-KELLP-----KDASGEIILETVELCDTWELELILNKPGLRYKPTCNQVVECHPYL 179
Query: 772 NLGQXELVDYCQSKGVVVVAYSPFG 846
N Q +L+++C+SK +V+VAYS G
Sbjct: 180 N--QSKLLEFCKSKDIVLVAYSALG 202
>AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydela) protein.
Length = 147
Score = 93.1 bits (221), Expect = 1e-18
Identities = 47/123 (38%), Positives = 71/123 (57%), Gaps = 1/123 (0%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
L+ G P +G G W ++ +++ A+ YA+ +GYRHID A +Y EPE+G
Sbjct: 8 LHTGQKMPLIGLGTWK----------SEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIG 57
Query: 412 EVINKKIKDG-VVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMS 588
E + + + G V RE+ FVT+K+W+ H DVE A+R L L LEY+DL L+ WP +
Sbjct: 58 EALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYA 117
Query: 589 ISQ 597
+
Sbjct: 118 FER 120
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 93.1 bits (221), Expect = 1e-18
Identities = 65/205 (31%), Positives = 105/205 (51%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + + T + +A AID+G+RHID+A+LY+ E EVG
Sbjct: 13 LNDGPFMPVLGFGTYAP-------DHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVG 65
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
+ I +KI DG VKRE+ F T K+W + V A+ L++L +YVDL ++ P ++
Sbjct: 66 QAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAM 125
Query: 592 SQEGVDENIDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXXAXRRQPDRDXL 771
Q G E + + G T ++ +L+ ++ + L
Sbjct: 126 KQPG-KELLP-----KDASGEIILETVELCDTWELELILNKPGLRYKPTCNQVVECHPYL 179
Query: 772 NLGQXELVDYCQSKGVVVVAYSPFG 846
N Q +L+++C+SK +V+VAYS G
Sbjct: 180 N--QSKLLEFCKSKDIVLVAYSALG 202
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 90.2 bits (214), Expect = 8e-18
Identities = 60/180 (33%), Positives = 93/180 (51%), Gaps = 13/180 (7%)
Frame = +1
Query: 346 AIDIGYRHIDTAHLYRVEPEVGEVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVR 525
AI+ G+RHID+A+LY E +VG I KI DG VKRED F T+K+W + V+ A+
Sbjct: 26 AIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALE 85
Query: 526 DCLRRLNLEYVDLVLVXWPMSISQEGV----DEN-------IDYLETWRGV*GGPQXGTX 672
L++L L+YVDL L+ +PM++ DEN +D TW + G
Sbjct: 86 SSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLA 145
Query: 673 QVHRRVQLQHRTDEEVTXQLXXAXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ R E + + + ++ + L Q +L+D+C+SK +V+VA+S G
Sbjct: 146 KSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 205
Score = 33.9 bits (74), Expect = 0.77
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Frame = +2
Query: 614 ISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
+S TW E E+ GL +SIGVSNFN Q++ +L + NQ+E
Sbjct: 129 LSATW---EVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVE 177
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 87.4 bits (207), Expect = 6e-17
Identities = 63/205 (30%), Positives = 94/205 (45%), Gaps = 15/205 (7%)
Frame = +1
Query: 277 LGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVGEVINKKIKDGVVKRE 456
+GL E + T ++ AID GYRHID A++Y+ E EVGE I +KI +G V+RE
Sbjct: 21 IGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVRRE 80
Query: 457 DXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSISQEGV----DENIDY 624
D F K+W +H V + LR L L+YVDL ++ PM+ DEN +
Sbjct: 81 DIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDENGKW 140
Query: 625 L-------ETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXXAXRRQPDRDXLN--- 774
L TW + G + R E + + + +P + +
Sbjct: 141 LYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNK--PGLKHKPVSNQVECHP 198
Query: 775 -LGQXELVDYCQSKGVVVVAYSPFG 846
Q +L+ +CQ +V+ AYSP G
Sbjct: 199 YFTQPKLLKFCQQHDIVITAYSPLG 223
Score = 30.3 bits (65), Expect = 9.5
Identities = 15/39 (38%), Positives = 22/39 (56%)
Frame = +2
Query: 608 TKISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLL 724
+ + TW E E GL +S+GVSNFN Q++ +L
Sbjct: 145 SNLCATW---EAMEACKDAGLVKSLGVSNFNRRQLELIL 180
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 87.4 bits (207), Expect = 6e-17
Identities = 63/205 (30%), Positives = 94/205 (45%), Gaps = 15/205 (7%)
Frame = +1
Query: 277 LGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVGEVINKKIKDGVVKRE 456
+GL E + T ++ AID GYRHID A++Y+ E EVGE I +KI +G V+RE
Sbjct: 21 IGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVRRE 80
Query: 457 DXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSISQEGV----DENIDY 624
D F K+W +H V + LR L L+YVDL ++ PM+ DEN +
Sbjct: 81 DIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDENGKW 140
Query: 625 L-------ETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXXAXRRQPDRDXLN--- 774
L TW + G + R E + + + +P + +
Sbjct: 141 LYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNK--PGLKHKPVSNQVECHP 198
Query: 775 -LGQXELVDYCQSKGVVVVAYSPFG 846
Q +L+ +CQ +V+ AYSP G
Sbjct: 199 YFTQPKLLKFCQQHDIVITAYSPLG 223
Score = 30.3 bits (65), Expect = 9.5
Identities = 15/39 (38%), Positives = 22/39 (56%)
Frame = +2
Query: 608 TKISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLL 724
+ + TW E E GL +S+GVSNFN Q++ +L
Sbjct: 145 SNLCATW---EAMEACKDAGLVKSLGVSNFNRRQLELIL 180
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 87.4 bits (207), Expect = 6e-17
Identities = 63/205 (30%), Positives = 94/205 (45%), Gaps = 15/205 (7%)
Frame = +1
Query: 277 LGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVGEVINKKIKDGVVKRE 456
+GL E + T ++ AID GYRHID A++Y+ E EVGE I +KI +G V+RE
Sbjct: 21 IGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVRRE 80
Query: 457 DXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSISQEGV----DENIDY 624
D F K+W +H V + LR L L+YVDL ++ PM+ DEN +
Sbjct: 81 DIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDENGKW 140
Query: 625 L-------ETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXXAXRRQPDRDXLN--- 774
L TW + G + R E + + + +P + +
Sbjct: 141 LYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNK--PGLKHKPVSNQVECHP 198
Query: 775 -LGQXELVDYCQSKGVVVVAYSPFG 846
Q +L+ +CQ +V+ AYSP G
Sbjct: 199 YFTQPKLLKFCQQHDIVITAYSPLG 223
Score = 30.3 bits (65), Expect = 9.5
Identities = 15/39 (38%), Positives = 22/39 (56%)
Frame = +2
Query: 608 TKISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLL 724
+ + TW E E GL +S+GVSNFN Q++ +L
Sbjct: 145 SNLCATW---EAMEACKDAGLVKSLGVSNFNRRQLELIL 180
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 87.4 bits (207), Expect = 6e-17
Identities = 63/205 (30%), Positives = 94/205 (45%), Gaps = 15/205 (7%)
Frame = +1
Query: 277 LGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVGEVINKKIKDGVVKRE 456
+GL E + T ++ AID GYRHID A++Y+ E EVGE I +KI +G V+RE
Sbjct: 21 IGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVRRE 80
Query: 457 DXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSISQEGV----DENIDY 624
D F K+W +H V + LR L L+YVDL ++ PM+ DEN +
Sbjct: 81 DIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDENGKW 140
Query: 625 L-------ETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQLXXAXRRQPDRDXLN--- 774
L TW + G + R E + + + +P + +
Sbjct: 141 LYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNK--PGLKHKPVSNQVECHP 198
Query: 775 -LGQXELVDYCQSKGVVVVAYSPFG 846
Q +L+ +CQ +V+ AYSP G
Sbjct: 199 YFTQPKLLKFCQQHDIVITAYSPLG 223
Score = 30.3 bits (65), Expect = 9.5
Identities = 15/39 (38%), Positives = 22/39 (56%)
Frame = +2
Query: 608 TKISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLL 724
+ + TW E E GL +S+GVSNFN Q++ +L
Sbjct: 145 SNLCATW---EAMEACKDAGLVKSLGVSNFNRRQLELIL 180
>BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 87.0 bits (206), Expect = 8e-17
Identities = 46/120 (38%), Positives = 70/120 (58%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + + T + +A AID+G+RHID+A+LY+ E EVG
Sbjct: 13 LNDGPFMPVLGFGTYAP-------DHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVG 65
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
+ I +KI DG VKRE+ F T K+W + V A+ L++L +YVDL ++ P ++
Sbjct: 66 QAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAM 125
>BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 87.0 bits (206), Expect = 8e-17
Identities = 46/120 (38%), Positives = 70/120 (58%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + + T + +A AID+G+RHID+A+LY+ E EVG
Sbjct: 13 LNDGPFMPVLGFGTYAP-------DHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVG 65
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
+ I +KI DG VKRE+ F T K+W + V A+ L++L +YVDL ++ P ++
Sbjct: 66 QAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAM 125
>AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ16347 fis, clone TESTI2036288, moderately
similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
Length = 129
Score = 87.0 bits (206), Expect = 8e-17
Identities = 46/120 (38%), Positives = 70/120 (58%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + + T + +A AID+G+RHID+A+LY+ E EVG
Sbjct: 13 LNDGPFMPVLGFGTYAP-------DHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVG 65
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
+ I +KI DG VKRE+ F T K+W + V A+ L++L +YVDL ++ P ++
Sbjct: 66 QAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAM 125
>AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto
reductase protein.
Length = 130
Score = 84.2 bits (199), Expect = 6e-16
Identities = 44/120 (36%), Positives = 68/120 (56%)
Frame = +1
Query: 232 LNNGIXFPALGYGXWLGLNXKXEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 411
LN+G P LG+G + +++A+ AID+GYRHID+A+ + E +G
Sbjct: 11 LNDGKFMPILGFGTSVARKVAMS-------NVEEAVQVAIDVGYRHIDSAYTHLNEEGIG 63
Query: 412 EVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWPMSI 591
+ I KKI +G VKR+D F TTKVW + V+ + L++L L Y+DL L +P+ +
Sbjct: 64 QAIRKKIANGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVPL 123
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 76.2 bits (179), Expect = 1e-13
Identities = 53/161 (32%), Positives = 80/161 (49%), Gaps = 13/161 (8%)
Frame = +1
Query: 403 EVGEVINKKIKDGVVKREDXFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVXWP 582
EVG I KI DG VKRED F T+K+W + H+ V A+ L+ L L+YVDL L+ +P
Sbjct: 26 EVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 85
Query: 583 MSI--SQEGV--DEN-------IDYLETWRGV*GGPQXGTXQVHRRVQLQHRTDEEVTXQ 729
+S+ +E + DEN +D TW V G + R E + +
Sbjct: 86 VSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNK 145
Query: 730 LXXAXRRQPDRDXLN--LGQXELVDYCQSKGVVVVAYSPFG 846
+ ++ + Q +L+D+C+SK +V+VAYS G
Sbjct: 146 PGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 186
Score = 31.9 bits (69), Expect = 3.1
Identities = 19/52 (36%), Positives = 27/52 (51%), Gaps = 2/52 (3%)
Frame = +2
Query: 614 ISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLLXNXXV--PXAVNQIE 763
+ TW E E+ GL +SIGVSNFN Q++ +L + NQ+E
Sbjct: 110 LCATW---EAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 158
>AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthase
protein.
Length = 67
Score = 33.9 bits (74), Expect = 0.77
Identities = 17/37 (45%), Positives = 23/37 (62%)
Frame = +2
Query: 614 ISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLL 724
+ TTW E E+ GL +SIGVSNFN Q++ +L
Sbjct: 21 LCTTW---EAMEKCKDAGLAKSIGVSNFNRRQLEMIL 54
>AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens
cDNA FLJ25413 fis, clone TST03402, highly similar to
3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ).
Length = 146
Score = 30.3 bits (65), Expect = 9.5
Identities = 15/39 (38%), Positives = 22/39 (56%)
Frame = +2
Query: 608 TKISTTWRRGEGFEEVLKXGLXRSIGVSNFNIEQMKRLL 724
+ + TW E E GL +S+GVSNFN Q++ +L
Sbjct: 23 SNLCATW---EAMEACKDAGLVKSLGVSNFNRRQLELIL 58
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 92,140,883
Number of Sequences: 237096
Number of extensions: 1663193
Number of successful extensions: 3848
Number of sequences better than 10.0: 92
Number of HSP's better than 10.0 without gapping: 3539
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3766
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11104084400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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