Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP16_F_F10
(890 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
J04031-1|AAA59574.1| 935|Homo sapiens MTHFD protein. 132 2e-30
BC050420-1|AAH50420.1| 935|Homo sapiens methylenetetrahydrofola... 132 2e-30
BC009806-1|AAH09806.1| 935|Homo sapiens methylenetetrahydrofola... 132 2e-30
X16396-1|CAA34431.1| 344|Homo sapiens protein ( Human mRNA for ... 71 4e-12
BC017054-1|AAH17054.2| 350|Homo sapiens methylenetetrahydrofola... 71 4e-12
BC001548-1|AAH01548.1| 344|Homo sapiens methylene tetrahydrofol... 71 4e-12
AK223041-1|BAD96761.1| 344|Homo sapiens methylene tetrahydrofol... 71 4e-12
AC073263-5|AAX93061.1| 344|Homo sapiens unknown protein. 71 4e-12
AK222826-1|BAD96546.1| 344|Homo sapiens methylene tetrahydrofol... 70 1e-11
AY374131-1|AAQ82697.1| 275|Homo sapiens truncated C1-tetrahydro... 57 1e-07
AY374130-1|AAQ82696.1| 978|Homo sapiens C1-tetrahydrofolate syn... 57 1e-07
AL133260-2|CAI95678.1| 978|Homo sapiens methylenetetrahydrofola... 57 1e-07
AL117452-1|CAB55934.1| 917|Homo sapiens hypothetical protein pr... 57 1e-07
AL049694-4|CAI95775.1| 331|Homo sapiens methylenetetrahydrofola... 57 1e-07
AL049694-3|CAI95774.1| 978|Homo sapiens methylenetetrahydrofola... 57 1e-07
AL035086-8|CAI42795.1| 331|Homo sapiens methylenetetrahydrofola... 57 1e-07
AL035086-7|CAI42794.1| 978|Homo sapiens methylenetetrahydrofola... 57 1e-07
AB127387-1|BAD93193.1| 978|Homo sapiens mitochondrial C1-tetrah... 57 1e-07
BC015062-1|AAH15062.1| 248|Homo sapiens methylenetetrahydrofola... 56 1e-07
BC110319-1|AAI10320.1| 900|Homo sapiens MTHFD1L protein protein. 56 2e-07
AL035086-6|CAI42793.1| 114|Homo sapiens methylenetetrahydrofola... 46 2e-04
BC037529-1|AAH37529.2| 106|Homo sapiens MTHFD2L protein protein. 42 0.004
BC032771-1|AAH32771.1| 146|Homo sapiens MTHFD2L protein protein. 38 0.049
BC058894-1|AAH58894.1| 587|Homo sapiens transcription factor 7-... 30 9.8
AC093162-1|AAY24094.1| 441|Homo sapiens unknown protein. 30 9.8
AB031046-1|BAB18185.1| 588|Homo sapiens HMG-box transcription f... 30 9.8
>J04031-1|AAA59574.1| 935|Homo sapiens MTHFD protein.
Length = 935
Score = 132 bits (319), Expect = 2e-30
Identities = 76/197 (38%), Positives = 108/197 (54%), Gaps = 1/197 (0%)
Frame = +2
Query: 92 AQIISGIEVAGSIXNDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYXXXXXXXXXXX 271
A+I++G E++ I L+ QVT+L+ + GF PRLAI+QVG R+DSN+Y
Sbjct: 4 AEILNGKEISAQIRARLKNQVTQLKEQVPGFTPRLAILQVGNRDDSNLYINVKLKAAEEI 63
Query: 272 XXXXXHIRLPRDITEIELLXKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKX 451
HI+LPR TE E++ ITSLNE +VHG +VQ+PLDS+++I+ V +A++P+K
Sbjct: 64 GIKATHIKLPRTTTESEVMKYITSLNEDSTVHGFLVQLPLDSENSINTEEVINAIAPEKD 123
Query: 452 VDXLNTINEGXXAVXDLS-XFIPLXLQPGAWNSLRXPXSLYLXKMW*CSGGVPLWVXRCQ 628
VD L +IN G A DL+ FIP G ++ + G +
Sbjct: 124 VDGLTSINAGRLARGDLNDCFIP-CTPKGCLELIKETGVPIAGRHAVVVGRSKIVGAPMH 182
Query: 629 SCXNXNTPTVTVCHSKT 679
N TVT CHSKT
Sbjct: 183 DLLLWNNATVTTCHSKT 199
Score = 43.2 bits (97), Expect = 0.001
Identities = 20/38 (52%), Positives = 26/38 (68%)
Frame = +1
Query: 523 TPAGCVELIKXTXXTIPXKNVVVLRRSPIVGTPVSELL 636
TP GC+ELIK T I ++ VV+ RS IVG P+ +LL
Sbjct: 148 TPKGCLELIKETGVPIAGRHAVVVGRSKIVGAPMHDLL 185
>BC050420-1|AAH50420.1| 935|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1, methenyltetrahydro
protein.
Length = 935
Score = 132 bits (319), Expect = 2e-30
Identities = 76/197 (38%), Positives = 108/197 (54%), Gaps = 1/197 (0%)
Frame = +2
Query: 92 AQIISGIEVAGSIXNDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYXXXXXXXXXXX 271
A+I++G E++ I L+ QVT+L+ + GF PRLAI+QVG R+DSN+Y
Sbjct: 4 AEILNGKEISAQIRARLKNQVTQLKEQVPGFTPRLAILQVGNRDDSNLYINVKLKAAEEI 63
Query: 272 XXXXXHIRLPRDITEIELLXKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKX 451
HI+LPR TE E++ ITSLNE +VHG +VQ+PLDS+++I+ V +A++P+K
Sbjct: 64 GIKATHIKLPRTTTESEVMKYITSLNEDSTVHGFLVQLPLDSENSINTEEVINAIAPEKD 123
Query: 452 VDXLNTINEGXXAVXDLS-XFIPLXLQPGAWNSLRXPXSLYLXKMW*CSGGVPLWVXRCQ 628
VD L +IN G A DL+ FIP G ++ + G +
Sbjct: 124 VDGLTSINAGRLARGDLNDCFIP-CTPKGCLELIKETGVPIAGRHAVVVGRSKIVGAPMH 182
Query: 629 SCXNXNTPTVTVCHSKT 679
N TVT CHSKT
Sbjct: 183 DLLLWNNATVTTCHSKT 199
Score = 43.2 bits (97), Expect = 0.001
Identities = 20/38 (52%), Positives = 26/38 (68%)
Frame = +1
Query: 523 TPAGCVELIKXTXXTIPXKNVVVLRRSPIVGTPVSELL 636
TP GC+ELIK T I ++ VV+ RS IVG P+ +LL
Sbjct: 148 TPKGCLELIKETGVPIAGRHAVVVGRSKIVGAPMHDLL 185
>BC009806-1|AAH09806.1| 935|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1, methenyltetrahydro
protein.
Length = 935
Score = 132 bits (319), Expect = 2e-30
Identities = 76/197 (38%), Positives = 108/197 (54%), Gaps = 1/197 (0%)
Frame = +2
Query: 92 AQIISGIEVAGSIXNDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYXXXXXXXXXXX 271
A+I++G E++ I L+ QVT+L+ + GF PRLAI+QVG R+DSN+Y
Sbjct: 4 AEILNGKEISAQIRARLKNQVTQLKEQVPGFTPRLAILQVGNRDDSNLYINVKLKAAEEI 63
Query: 272 XXXXXHIRLPRDITEIELLXKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKX 451
HI+LPR TE E++ ITSLNE +VHG +VQ+PLDS+++I+ V +A++P+K
Sbjct: 64 GIKATHIKLPRTTTESEVMKYITSLNEDSTVHGFLVQLPLDSENSINTEEVINAIAPEKD 123
Query: 452 VDXLNTINEGXXAVXDLS-XFIPLXLQPGAWNSLRXPXSLYLXKMW*CSGGVPLWVXRCQ 628
VD L +IN G A DL+ FIP G ++ + G +
Sbjct: 124 VDGLTSINAGRLARGDLNDCFIP-CTPKGCLELIKETGVPIAGRHAVVVGRSKIVGAPMH 182
Query: 629 SCXNXNTPTVTVCHSKT 679
N TVT CHSKT
Sbjct: 183 DLLLWNNATVTTCHSKT 199
Score = 43.2 bits (97), Expect = 0.001
Identities = 20/38 (52%), Positives = 26/38 (68%)
Frame = +1
Query: 523 TPAGCVELIKXTXXTIPXKNVVVLRRSPIVGTPVSELL 636
TP GC+ELIK T I ++ VV+ RS IVG P+ +LL
Sbjct: 148 TPKGCLELIKETGVPIAGRHAVVVGRSKIVGAPMHDLL 185
>X16396-1|CAA34431.1| 344|Homo sapiens protein ( Human mRNA for
NAD-dependent methylene tetrahydrofolate dehydrogenase
cyclohydrolase (EC 1.5.1.15). ).
Length = 344
Score = 71.3 bits (167), Expect = 4e-12
Identities = 47/138 (34%), Positives = 69/138 (50%)
Frame = +2
Query: 92 AQIISGIEVAGSIXNDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYXXXXXXXXXXX 271
A +ISG ++A I ++RQ+V + + P L+++ VG S+ Y
Sbjct: 31 AVVISGRKLAQQIKQEVRQEVEEWVASGNK-RPHLSVILVGENPASHSYVLNKTRAAAVV 89
Query: 272 XXXXXHIRLPRDITEIELLXKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKX 451
I P I+E ELL I LN +V G++VQ+PL +H ID R+ +AVSPDK
Sbjct: 90 GINSETIMKPASISEEELLNLINKLNNDDNVDGLLVQLPL-PEH-IDERRICNAVSPDKD 147
Query: 452 VDXLNTINEGXXAVXDLS 505
VD + IN G + S
Sbjct: 148 VDGFHVINVGRMCLDQYS 165
Score = 33.9 bits (74), Expect = 0.80
Identities = 19/38 (50%), Positives = 22/38 (57%)
Frame = +1
Query: 523 TPAGCVELIKXTXXTIPXKNVVVLRRSPIVGTPVSELL 636
TP G E+IK T KNVVV RS VG P++ LL
Sbjct: 170 TPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLL 207
>BC017054-1|AAH17054.2| 350|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 2, methenyltetrahydro
protein.
Length = 350
Score = 71.3 bits (167), Expect = 4e-12
Identities = 47/138 (34%), Positives = 69/138 (50%)
Frame = +2
Query: 92 AQIISGIEVAGSIXNDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYXXXXXXXXXXX 271
A +ISG ++A I ++RQ+V + + P L+++ VG S+ Y
Sbjct: 37 AVVISGRKLAQQIKQEVRQEVEEWVASGNK-RPHLSVILVGENPASHSYVLNKTRAAAVV 95
Query: 272 XXXXXHIRLPRDITEIELLXKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKX 451
I P I+E ELL I LN +V G++VQ+PL +H ID R+ +AVSPDK
Sbjct: 96 GINSETIMKPASISEEELLNLINKLNNDDNVDGLLVQLPL-PEH-IDERRICNAVSPDKD 153
Query: 452 VDXLNTINEGXXAVXDLS 505
VD + IN G + S
Sbjct: 154 VDGFHVINVGRMCLDQYS 171
Score = 33.9 bits (74), Expect = 0.80
Identities = 19/38 (50%), Positives = 22/38 (57%)
Frame = +1
Query: 523 TPAGCVELIKXTXXTIPXKNVVVLRRSPIVGTPVSELL 636
TP G E+IK T KNVVV RS VG P++ LL
Sbjct: 176 TPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLL 213
>BC001548-1|AAH01548.1| 344|Homo sapiens methylene tetrahydrofolate
dehydrogenase 2, precursor protein.
Length = 344
Score = 71.3 bits (167), Expect = 4e-12
Identities = 47/138 (34%), Positives = 69/138 (50%)
Frame = +2
Query: 92 AQIISGIEVAGSIXNDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYXXXXXXXXXXX 271
A +ISG ++A I ++RQ+V + + P L+++ VG S+ Y
Sbjct: 31 AVVISGRKLAQQIKQEVRQEVEEWVASGNK-RPHLSVILVGENPASHSYVLNKTRAAAVV 89
Query: 272 XXXXXHIRLPRDITEIELLXKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKX 451
I P I+E ELL I LN +V G++VQ+PL +H ID R+ +AVSPDK
Sbjct: 90 GINSETIMKPASISEEELLNLINKLNNDDNVDGLLVQLPL-PEH-IDERRICNAVSPDKD 147
Query: 452 VDXLNTINEGXXAVXDLS 505
VD + IN G + S
Sbjct: 148 VDGFHVINVGRMCLDQYS 165
Score = 33.9 bits (74), Expect = 0.80
Identities = 19/38 (50%), Positives = 22/38 (57%)
Frame = +1
Query: 523 TPAGCVELIKXTXXTIPXKNVVVLRRSPIVGTPVSELL 636
TP G E+IK T KNVVV RS VG P++ LL
Sbjct: 170 TPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLL 207
>AK223041-1|BAD96761.1| 344|Homo sapiens methylene tetrahydrofolate
dehydrogenase 2 precursor variant protein.
Length = 344
Score = 71.3 bits (167), Expect = 4e-12
Identities = 47/138 (34%), Positives = 69/138 (50%)
Frame = +2
Query: 92 AQIISGIEVAGSIXNDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYXXXXXXXXXXX 271
A +ISG ++A I ++RQ+V + + P L+++ VG S+ Y
Sbjct: 31 AVVISGRKLAQQIKQEVRQEVEEWVASGNK-RPHLSVILVGENPASHSYVLNKTRAAAVA 89
Query: 272 XXXXXHIRLPRDITEIELLXKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKX 451
I P I+E ELL I LN +V G++VQ+PL +H ID R+ +AVSPDK
Sbjct: 90 GINSETIMKPASISEEELLNLINKLNNDDNVDGLLVQLPL-PEH-IDERRICNAVSPDKD 147
Query: 452 VDXLNTINEGXXAVXDLS 505
VD + IN G + S
Sbjct: 148 VDGFHVINVGRMCLDQYS 165
Score = 33.9 bits (74), Expect = 0.80
Identities = 19/38 (50%), Positives = 22/38 (57%)
Frame = +1
Query: 523 TPAGCVELIKXTXXTIPXKNVVVLRRSPIVGTPVSELL 636
TP G E+IK T KNVVV RS VG P++ LL
Sbjct: 170 TPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLL 207
>AC073263-5|AAX93061.1| 344|Homo sapiens unknown protein.
Length = 344
Score = 71.3 bits (167), Expect = 4e-12
Identities = 47/138 (34%), Positives = 69/138 (50%)
Frame = +2
Query: 92 AQIISGIEVAGSIXNDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYXXXXXXXXXXX 271
A +ISG ++A I ++RQ+V + + P L+++ VG S+ Y
Sbjct: 31 AVVISGRKLAQQIKQEVRQEVEEWVASGNK-RPHLSVILVGENPASHSYVLNKTRAAAVV 89
Query: 272 XXXXXHIRLPRDITEIELLXKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKX 451
I P I+E ELL I LN +V G++VQ+PL +H ID R+ +AVSPDK
Sbjct: 90 GINSETIMKPASISEEELLNLINKLNNDDNVDGLLVQLPL-PEH-IDERRICNAVSPDKD 147
Query: 452 VDXLNTINEGXXAVXDLS 505
VD + IN G + S
Sbjct: 148 VDGFHVINVGRMCLDQYS 165
Score = 33.9 bits (74), Expect = 0.80
Identities = 19/38 (50%), Positives = 22/38 (57%)
Frame = +1
Query: 523 TPAGCVELIKXTXXTIPXKNVVVLRRSPIVGTPVSELL 636
TP G E+IK T KNVVV RS VG P++ LL
Sbjct: 170 TPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLL 207
>AK222826-1|BAD96546.1| 344|Homo sapiens methylene tetrahydrofolate
dehydrogenase 2 precursor variant protein.
Length = 344
Score = 69.7 bits (163), Expect = 1e-11
Identities = 46/138 (33%), Positives = 68/138 (49%)
Frame = +2
Query: 92 AQIISGIEVAGSIXNDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYXXXXXXXXXXX 271
A +ISG ++A I ++RQ+V + + P L+++ G S+ Y
Sbjct: 31 AVVISGRKLAQQIKQEVRQEVEEWVASGNK-RPHLSVILAGENPASHSYVLNKTRAAAVV 89
Query: 272 XXXXXHIRLPRDITEIELLXKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKX 451
I P I+E ELL I LN +V G++VQ+PL +H ID R+ +AVSPDK
Sbjct: 90 GINSETIMKPASISEEELLNLINKLNNDDNVDGLLVQLPL-PEH-IDERRICNAVSPDKD 147
Query: 452 VDXLNTINEGXXAVXDLS 505
VD + IN G + S
Sbjct: 148 VDGFHVINVGRMCLDQYS 165
Score = 33.9 bits (74), Expect = 0.80
Identities = 19/38 (50%), Positives = 22/38 (57%)
Frame = +1
Query: 523 TPAGCVELIKXTXXTIPXKNVVVLRRSPIVGTPVSELL 636
TP G E+IK T KNVVV RS VG P++ LL
Sbjct: 170 TPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLL 207
>AY374131-1|AAQ82697.1| 275|Homo sapiens truncated
C1-tetrahydrofolate synthase protein.
Length = 275
Score = 56.8 bits (131), Expect = 1e-07
Identities = 34/122 (27%), Positives = 61/122 (50%)
Frame = +2
Query: 116 VAGSIXNDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYXXXXXXXXXXXXXXXXHIR 295
+ + + ++ ++ L+ K F+P LAI+Q G D N+ HI
Sbjct: 74 IVREVIQNSKEVLSLLQEKNPAFKPVLAIIQAG---DDNLMQEINQNLAEEAGLNITHIC 130
Query: 296 LPRDITEIELLXKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKXVDXLNTIN 475
LP D +E E++ +I +NE VHG+ +Q+ + +++V +A+ P+K VD + IN
Sbjct: 131 LPPDSSEAEIIDEILKINEDTRVHGLALQI----SENLFSNKVLNALKPEKDVDGVTDIN 186
Query: 476 EG 481
G
Sbjct: 187 LG 188
>AY374130-1|AAQ82696.1| 978|Homo sapiens C1-tetrahydrofolate
synthase protein.
Length = 978
Score = 56.8 bits (131), Expect = 1e-07
Identities = 34/122 (27%), Positives = 61/122 (50%)
Frame = +2
Query: 116 VAGSIXNDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYXXXXXXXXXXXXXXXXHIR 295
+ + + ++ ++ L+ K F+P LAI+Q G D N+ HI
Sbjct: 74 IVREVIQNSKEVLSLLQEKNPAFKPVLAIIQAG---DDNLMQEINQNLAEEAGLNITHIC 130
Query: 296 LPRDITEIELLXKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKXVDXLNTIN 475
LP D +E E++ +I +NE VHG+ +Q+ + +++V +A+ P+K VD + IN
Sbjct: 131 LPPDSSEAEIIDEILKINEDTRVHGLALQI----SENLFSNKVLNALKPEKDVDGVTDIN 186
Query: 476 EG 481
G
Sbjct: 187 LG 188
>AL133260-2|CAI95678.1| 978|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1-like protein.
Length = 978
Score = 56.8 bits (131), Expect = 1e-07
Identities = 34/122 (27%), Positives = 61/122 (50%)
Frame = +2
Query: 116 VAGSIXNDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYXXXXXXXXXXXXXXXXHIR 295
+ + + ++ ++ L+ K F+P LAI+Q G D N+ HI
Sbjct: 74 IVREVIQNSKEVLSLLQEKNPAFKPVLAIIQAG---DDNLMQEINQNLAEEAGLNITHIC 130
Query: 296 LPRDITEIELLXKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKXVDXLNTIN 475
LP D +E E++ +I +NE VHG+ +Q+ + +++V +A+ P+K VD + IN
Sbjct: 131 LPPDSSEAEIIDEILKINEDTRVHGLALQI----SENLFSNKVLNALKPEKDVDGVTDIN 186
Query: 476 EG 481
G
Sbjct: 187 LG 188
>AL117452-1|CAB55934.1| 917|Homo sapiens hypothetical protein
protein.
Length = 917
Score = 56.8 bits (131), Expect = 1e-07
Identities = 34/122 (27%), Positives = 61/122 (50%)
Frame = +2
Query: 116 VAGSIXNDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYXXXXXXXXXXXXXXXXHIR 295
+ + + ++ ++ L+ K F+P LAI+Q G D N+ HI
Sbjct: 13 IVREVIQNSKEVLSLLQEKNPAFKPVLAIIQAG---DDNLMQEINQNLAEEAGLNITHIC 69
Query: 296 LPRDITEIELLXKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKXVDXLNTIN 475
LP D +E E++ +I +NE VHG+ +Q+ + +++V +A+ P+K VD + IN
Sbjct: 70 LPPDSSEAEIIDEILKINEDTRVHGLALQI----SENLFSNKVLNALKPEKDVDGVTDIN 125
Query: 476 EG 481
G
Sbjct: 126 LG 127
>AL049694-4|CAI95775.1| 331|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1-like protein.
Length = 331
Score = 56.8 bits (131), Expect = 1e-07
Identities = 34/122 (27%), Positives = 61/122 (50%)
Frame = +2
Query: 116 VAGSIXNDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYXXXXXXXXXXXXXXXXHIR 295
+ + + ++ ++ L+ K F+P LAI+Q G D N+ HI
Sbjct: 33 IVREVIQNSKEVLSLLQEKNPAFKPVLAIIQAG---DDNLMQEINQNLAEEAGLNITHIC 89
Query: 296 LPRDITEIELLXKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKXVDXLNTIN 475
LP D +E E++ +I +NE VHG+ +Q+ + +++V +A+ P+K VD + IN
Sbjct: 90 LPPDSSEAEIIDEILKINEDTRVHGLALQI----SENLFSNKVLNALKPEKDVDGVTDIN 145
Query: 476 EG 481
G
Sbjct: 146 LG 147
>AL049694-3|CAI95774.1| 978|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1-like protein.
Length = 978
Score = 56.8 bits (131), Expect = 1e-07
Identities = 34/122 (27%), Positives = 61/122 (50%)
Frame = +2
Query: 116 VAGSIXNDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYXXXXXXXXXXXXXXXXHIR 295
+ + + ++ ++ L+ K F+P LAI+Q G D N+ HI
Sbjct: 74 IVREVIQNSKEVLSLLQEKNPAFKPVLAIIQAG---DDNLMQEINQNLAEEAGLNITHIC 130
Query: 296 LPRDITEIELLXKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKXVDXLNTIN 475
LP D +E E++ +I +NE VHG+ +Q+ + +++V +A+ P+K VD + IN
Sbjct: 131 LPPDSSEAEIIDEILKINEDTRVHGLALQI----SENLFSNKVLNALKPEKDVDGVTDIN 186
Query: 476 EG 481
G
Sbjct: 187 LG 188
>AL035086-8|CAI42795.1| 331|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1-like protein.
Length = 331
Score = 56.8 bits (131), Expect = 1e-07
Identities = 34/122 (27%), Positives = 61/122 (50%)
Frame = +2
Query: 116 VAGSIXNDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYXXXXXXXXXXXXXXXXHIR 295
+ + + ++ ++ L+ K F+P LAI+Q G D N+ HI
Sbjct: 33 IVREVIQNSKEVLSLLQEKNPAFKPVLAIIQAG---DDNLMQEINQNLAEEAGLNITHIC 89
Query: 296 LPRDITEIELLXKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKXVDXLNTIN 475
LP D +E E++ +I +NE VHG+ +Q+ + +++V +A+ P+K VD + IN
Sbjct: 90 LPPDSSEAEIIDEILKINEDTRVHGLALQI----SENLFSNKVLNALKPEKDVDGVTDIN 145
Query: 476 EG 481
G
Sbjct: 146 LG 147
>AL035086-7|CAI42794.1| 978|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1-like protein.
Length = 978
Score = 56.8 bits (131), Expect = 1e-07
Identities = 34/122 (27%), Positives = 61/122 (50%)
Frame = +2
Query: 116 VAGSIXNDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYXXXXXXXXXXXXXXXXHIR 295
+ + + ++ ++ L+ K F+P LAI+Q G D N+ HI
Sbjct: 74 IVREVIQNSKEVLSLLQEKNPAFKPVLAIIQAG---DDNLMQEINQNLAEEAGLNITHIC 130
Query: 296 LPRDITEIELLXKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKXVDXLNTIN 475
LP D +E E++ +I +NE VHG+ +Q+ + +++V +A+ P+K VD + IN
Sbjct: 131 LPPDSSEAEIIDEILKINEDTRVHGLALQI----SENLFSNKVLNALKPEKDVDGVTDIN 186
Query: 476 EG 481
G
Sbjct: 187 LG 188
>AB127387-1|BAD93193.1| 978|Homo sapiens mitochondrial
C1-tetrahydrofolate synthetase protein.
Length = 978
Score = 56.8 bits (131), Expect = 1e-07
Identities = 34/122 (27%), Positives = 61/122 (50%)
Frame = +2
Query: 116 VAGSIXNDLRQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYXXXXXXXXXXXXXXXXHIR 295
+ + + ++ ++ L+ K F+P LAI+Q G D N+ HI
Sbjct: 74 IVREVIQNSKEVLSLLQEKNPAFKPVLAIIQAG---DDNLMQEINQNLAEEAGLNITHIC 130
Query: 296 LPRDITEIELLXKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKXVDXLNTIN 475
LP D +E E++ +I +NE VHG+ +Q+ + +++V +A+ P+K VD + IN
Sbjct: 131 LPPDSSEAEIIDEILKINEDTRVHGLALQI----SENLFSNKVLNALKPEKDVDGVTDIN 186
Query: 476 EG 481
G
Sbjct: 187 LG 188
>BC015062-1|AAH15062.1| 248|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 2, methenyltetrahydro
protein.
Length = 248
Score = 56.4 bits (130), Expect = 1e-07
Identities = 31/69 (44%), Positives = 41/69 (59%)
Frame = +2
Query: 299 PRDITEIELLXKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKXVDXLNTINE 478
P I+E ELL I LN +V G++VQ+PL +H ID R+ +AVSPDK VD + IN
Sbjct: 3 PASISEEELLNLINKLNNDDNVDGLLVQLPL-PEH-IDERRICNAVSPDKDVDGFHVINV 60
Query: 479 GXXAVXDLS 505
G + S
Sbjct: 61 GRMCLDQYS 69
Score = 33.9 bits (74), Expect = 0.80
Identities = 19/38 (50%), Positives = 22/38 (57%)
Frame = +1
Query: 523 TPAGCVELIKXTXXTIPXKNVVVLRRSPIVGTPVSELL 636
TP G E+IK T KNVVV RS VG P++ LL
Sbjct: 74 TPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLL 111
>BC110319-1|AAI10320.1| 900|Homo sapiens MTHFD1L protein protein.
Length = 900
Score = 56.0 bits (129), Expect = 2e-07
Identities = 34/113 (30%), Positives = 58/113 (51%)
Frame = +2
Query: 143 RQQVTRLRSKWSGFEPRLAIVQVGGREDSNVYXXXXXXXXXXXXXXXXHIRLPRDITEIE 322
++ ++ L+ K F+P LAI+Q G D N+ HI LP D +E E
Sbjct: 5 KEVLSLLQEKNPAFKPVLAIIQAG---DDNLMQEINQNLAEEAGLNITHICLPPDSSEAE 61
Query: 323 LLXKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKXVDXLNTINEG 481
++ +I +NE VHG+ +Q+ + +++V +A+ P+K VD + IN G
Sbjct: 62 IIDEILKINEDTRVHGLALQI----SENLFSNKVLNALKPEKDVDGVTDINLG 110
>AL035086-6|CAI42793.1| 114|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1-like protein.
Length = 114
Score = 46.0 bits (104), Expect = 2e-04
Identities = 23/65 (35%), Positives = 39/65 (60%)
Frame = +2
Query: 287 HIRLPRDITEIELLXKITSLNESPSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKXVDXLN 466
HI LP D +E E++ +I +NE VHG+ +Q+ + +++V +A+ P+K VD +
Sbjct: 18 HICLPPDSSEAEIIDEILKINEDTRVHGLALQI----SENLFSNKVLNALKPEKDVDGVT 73
Query: 467 TINEG 481
IN G
Sbjct: 74 DINLG 78
>BC037529-1|AAH37529.2| 106|Homo sapiens MTHFD2L protein protein.
Length = 106
Score = 41.5 bits (93), Expect = 0.004
Identities = 23/68 (33%), Positives = 32/68 (47%)
Frame = +2
Query: 188 PRLAIVQVGGREDSNVYXXXXXXXXXXXXXXXXHIRLPRDITEIELLXKITSLNESPSVH 367
P L+I+ VG S+ Y I P+D+++ ELL LN P V
Sbjct: 24 PHLSIILVGDNPASHTYVRNKIRAASAVGICSELILKPKDVSQEELLDVTDQLNMDPRVS 83
Query: 368 GIIVQMPL 391
GI+VQ+PL
Sbjct: 84 GILVQLPL 91
>BC032771-1|AAH32771.1| 146|Homo sapiens MTHFD2L protein protein.
Length = 146
Score = 37.9 bits (84), Expect = 0.049
Identities = 21/54 (38%), Positives = 31/54 (57%)
Frame = +2
Query: 356 PSVHGIIVQMPLDSDHAIDAHRVTDAVSPDKXVDXLNTINEGXXAVXDLSXFIP 517
P V GI+VQ+PL DH +D + + ++P+K VD + IN G + D IP
Sbjct: 3 PRVSGILVQLPL-PDH-VDERTICNGIAPEKDVDGFHIINIGRLCL-DQHSLIP 53
>BC058894-1|AAH58894.1| 587|Homo sapiens transcription factor
7-like 1 (T-cell specific, HMG-box) protein.
Length = 587
Score = 30.3 bits (65), Expect = 9.8
Identities = 20/53 (37%), Positives = 28/53 (52%)
Frame = -2
Query: 235 DVRVLAPAHLHDGKPGLEARPF*TEPSHLLTQVIXYRSCNFNPRYNLCHLSPE 77
D R +PAHL + P ++ P H LT +I Y + +F+P HLSPE
Sbjct: 165 DTRSPSPAHLSNKVPVVQ-HP---HHMHPLTPLITYSNDHFSPGSPPTHLSPE 213
>AC093162-1|AAY24094.1| 441|Homo sapiens unknown protein.
Length = 441
Score = 30.3 bits (65), Expect = 9.8
Identities = 20/53 (37%), Positives = 28/53 (52%)
Frame = -2
Query: 235 DVRVLAPAHLHDGKPGLEARPF*TEPSHLLTQVIXYRSCNFNPRYNLCHLSPE 77
D R +PAHL + P ++ P H LT +I Y + +F+P HLSPE
Sbjct: 19 DTRSPSPAHLSNKVPVVQ-HP---HHMHPLTPLITYSNDHFSPGSPPTHLSPE 67
>AB031046-1|BAB18185.1| 588|Homo sapiens HMG-box transcription
factor TCF-3 protein.
Length = 588
Score = 30.3 bits (65), Expect = 9.8
Identities = 20/53 (37%), Positives = 28/53 (52%)
Frame = -2
Query: 235 DVRVLAPAHLHDGKPGLEARPF*TEPSHLLTQVIXYRSCNFNPRYNLCHLSPE 77
D R +PAHL + P ++ P H LT +I Y + +F+P HLSPE
Sbjct: 166 DTRSPSPAHLSNKVPVVQ-HP---HHMHPLTPLITYSNDHFSPGSPPTHLSPE 214
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 93,964,239
Number of Sequences: 237096
Number of extensions: 1455415
Number of successful extensions: 2559
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 2501
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2533
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11437206932
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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