Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP16_F_E22
(879 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC000126-1|AAH00126.1| 310|Homo sapiens sirtuin (silent mating ... 166 8e-41
AL441883-2|CAI19838.1| 310|Homo sapiens sirtuin (silent mating ... 166 8e-41
AL441883-1|CAI19837.1| 299|Homo sapiens sirtuin (silent mating ... 166 8e-41
AK000355-1|BAA91107.1| 299|Homo sapiens protein ( Homo sapiens ... 166 8e-41
AF083110-1|AAD40853.1| 310|Homo sapiens sirtuin type 5 protein. 166 8e-41
BC109320-1|AAI09321.1| 314|Homo sapiens sirtuin (silent mating ... 46 1e-04
BC109319-1|AAI09320.1| 314|Homo sapiens sirtuin (silent mating ... 46 1e-04
AF083109-1|AAD40852.1| 314|Homo sapiens sirtuin type 4 protein. 46 1e-04
BC101793-1|AAI01794.1| 400|Homo sapiens sirtuin (silent mating ... 40 0.012
BC101791-1|AAI01792.1| 400|Homo sapiens sirtuin (silent mating ... 40 0.012
BC017305-1|AAH17305.1| 400|Homo sapiens sirtuin (silent mating ... 40 0.012
AK002027-1|BAA92044.1| 183|Homo sapiens protein ( Homo sapiens ... 40 0.012
AF233395-1|AAF43431.1| 400|Homo sapiens sir2-related protein ty... 40 0.012
DQ278604-1|ABB72675.1| 747|Homo sapiens sirtuin (silent mating ... 38 0.036
BC012499-1|AAH12499.1| 555|Homo sapiens SIRT1 protein protein. 38 0.036
AL133551-8|CAI16036.1| 747|Homo sapiens sirtuin (silent mating ... 38 0.036
AF235040-1|AAG38486.1| 747|Homo sapiens SIR2alpha protein protein. 38 0.036
AF083106-1|AAD40849.2| 747|Homo sapiens sirtuin type 1 protein. 38 0.036
CR457200-1|CAG33481.1| 355|Homo sapiens SIRT6 protein. 38 0.048
BC001042-1|AAH01042.1| 399|Homo sapiens sirtuin (silent mating ... 38 0.063
AF083108-1|AAD40851.1| 399|Homo sapiens sirtuin type 3 protein. 38 0.063
AC003982-1|AAB95634.1| 326|Homo sapiens WUGSC:H_166H1.1 protein. 37 0.084
BC028220-1|AAH28220.1| 328|Homo sapiens SIRT6 protein protein. 37 0.11
BC005026-1|AAH05026.1| 355|Homo sapiens sirtuin (silent mating ... 37 0.11
AK074810-1|BAC11222.1| 355|Homo sapiens protein ( Homo sapiens ... 37 0.11
AF233396-1|AAF43432.1| 355|Homo sapiens sir2-related protein ty... 37 0.11
AC006930-1|AAD15478.1| 377|Homo sapiens R33423_1 protein. 37 0.11
BC003547-1|AAH03547.1| 352|Homo sapiens sirtuin (silent mating ... 33 1.0
BC003012-1|AAH03012.1| 352|Homo sapiens sirtuin (silent mating ... 33 1.0
AY030277-1|AAK51133.1| 352|Homo sapiens SIRT2 protein. 33 1.0
AF095714-1|AAD45971.1| 352|Homo sapiens silencing information r... 33 1.0
AF083107-1|AAD40850.2| 389|Homo sapiens sirtuin type 2 protein. 33 1.0
AF131800-1|AAD20046.1| 254|Homo sapiens Similar to rat 5E5 anti... 33 1.4
AJ505014-1|CAD43717.1| 369|Homo sapiens sirtuin type 2 protein. 33 1.8
AF160214-1|AAF67015.1| 373|Homo sapiens silent information regu... 32 2.4
>BC000126-1|AAH00126.1| 310|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 5 (S. cerevisiae)
protein.
Length = 310
Score = 166 bits (404), Expect = 8e-41
Identities = 88/223 (39%), Positives = 123/223 (55%)
Frame = +1
Query: 208 SSDFSKFRVALKSAKEIVILSGAGISAESGIPTFRGAGGLWEEISSFGLSNXRSF*RKSK 387
SS + FR AK IVI+SGAG+SAESG+PTFRGAGG W + + L+ +F
Sbjct: 37 SSSMADFRKFFAKAKHIVIISGAGVSAESGVPTFRGAGGYWRKWQAQDLATPLAFAHNPS 96
Query: 388 LSMGILPLQKRGGQQRRKPNAGHFGYC*NSKXTMXFPKKITVITQNVGWVTCPEQETKRL 567
+R ++PNAGH +++ VITQN+ + + TK L
Sbjct: 97 RVWEFYHY-RREVMGSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELH-RKAGTKNL 154
Query: 568 IXLHXNLYQNSMYKCXEXLXNNDXPICXAXANRGAPXSNMVGSDIPVKLLPXCKKAHCGA 747
+ +H +L++ C N PIC A + +GAP + IPV+ LP C++A CG
Sbjct: 155 LEIHGSLFKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGG 214
Query: 748 LLTPHIVWFXESLEHDILEAAEHAMSTCDVCLXVGTSSVXYPA 876
LL PH+VWF E+L+ ILE + ++ CD+CL VGTSSV YPA
Sbjct: 215 LLRPHVVWFGENLDPAILEEVDRELAHCDLCLVVGTSSVVYPA 257
>AL441883-2|CAI19838.1| 310|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 5 (S. cerevisiae)
protein.
Length = 310
Score = 166 bits (404), Expect = 8e-41
Identities = 88/223 (39%), Positives = 123/223 (55%)
Frame = +1
Query: 208 SSDFSKFRVALKSAKEIVILSGAGISAESGIPTFRGAGGLWEEISSFGLSNXRSF*RKSK 387
SS + FR AK IVI+SGAG+SAESG+PTFRGAGG W + + L+ +F
Sbjct: 37 SSSMADFRKFFAKAKHIVIISGAGVSAESGVPTFRGAGGYWRKWQAQDLATPLAFAHNPS 96
Query: 388 LSMGILPLQKRGGQQRRKPNAGHFGYC*NSKXTMXFPKKITVITQNVGWVTCPEQETKRL 567
+R ++PNAGH +++ VITQN+ + + TK L
Sbjct: 97 RVWEFYHY-RREVMGSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELH-RKAGTKNL 154
Query: 568 IXLHXNLYQNSMYKCXEXLXNNDXPICXAXANRGAPXSNMVGSDIPVKLLPXCKKAHCGA 747
+ +H +L++ C N PIC A + +GAP + IPV+ LP C++A CG
Sbjct: 155 LEIHGSLFKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGG 214
Query: 748 LLTPHIVWFXESLEHDILEAAEHAMSTCDVCLXVGTSSVXYPA 876
LL PH+VWF E+L+ ILE + ++ CD+CL VGTSSV YPA
Sbjct: 215 LLRPHVVWFGENLDPAILEEVDRELAHCDLCLVVGTSSVVYPA 257
>AL441883-1|CAI19837.1| 299|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 5 (S. cerevisiae)
protein.
Length = 299
Score = 166 bits (404), Expect = 8e-41
Identities = 88/223 (39%), Positives = 123/223 (55%)
Frame = +1
Query: 208 SSDFSKFRVALKSAKEIVILSGAGISAESGIPTFRGAGGLWEEISSFGLSNXRSF*RKSK 387
SS + FR AK IVI+SGAG+SAESG+PTFRGAGG W + + L+ +F
Sbjct: 37 SSSMADFRKFFAKAKHIVIISGAGVSAESGVPTFRGAGGYWRKWQAQDLATPLAFAHNPS 96
Query: 388 LSMGILPLQKRGGQQRRKPNAGHFGYC*NSKXTMXFPKKITVITQNVGWVTCPEQETKRL 567
+R ++PNAGH +++ VITQN+ + + TK L
Sbjct: 97 RVWEFYHY-RREVMGSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELH-RKAGTKNL 154
Query: 568 IXLHXNLYQNSMYKCXEXLXNNDXPICXAXANRGAPXSNMVGSDIPVKLLPXCKKAHCGA 747
+ +H +L++ C N PIC A + +GAP + IPV+ LP C++A CG
Sbjct: 155 LEIHGSLFKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGG 214
Query: 748 LLTPHIVWFXESLEHDILEAAEHAMSTCDVCLXVGTSSVXYPA 876
LL PH+VWF E+L+ ILE + ++ CD+CL VGTSSV YPA
Sbjct: 215 LLRPHVVWFGENLDPAILEEVDRELAHCDLCLVVGTSSVVYPA 257
>AK000355-1|BAA91107.1| 299|Homo sapiens protein ( Homo sapiens
cDNA FLJ20348 fis, clone HEP13915. ).
Length = 299
Score = 166 bits (404), Expect = 8e-41
Identities = 88/223 (39%), Positives = 123/223 (55%)
Frame = +1
Query: 208 SSDFSKFRVALKSAKEIVILSGAGISAESGIPTFRGAGGLWEEISSFGLSNXRSF*RKSK 387
SS + FR AK IVI+SGAG+SAESG+PTFRGAGG W + + L+ +F
Sbjct: 37 SSSMADFRKFFAKAKHIVIISGAGVSAESGVPTFRGAGGYWRKWQAQDLATPLAFAHNPS 96
Query: 388 LSMGILPLQKRGGQQRRKPNAGHFGYC*NSKXTMXFPKKITVITQNVGWVTCPEQETKRL 567
+R ++PNAGH +++ VITQN+ + + TK L
Sbjct: 97 RVWEFYHY-RREVMGSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELH-RKAGTKNL 154
Query: 568 IXLHXNLYQNSMYKCXEXLXNNDXPICXAXANRGAPXSNMVGSDIPVKLLPXCKKAHCGA 747
+ +H +L++ C N PIC A + +GAP + IPV+ LP C++A CG
Sbjct: 155 LEIHGSLFKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGG 214
Query: 748 LLTPHIVWFXESLEHDILEAAEHAMSTCDVCLXVGTSSVXYPA 876
LL PH+VWF E+L+ ILE + ++ CD+CL VGTSSV YPA
Sbjct: 215 LLRPHVVWFGENLDPAILEEVDRELAHCDLCLVVGTSSVVYPA 257
>AF083110-1|AAD40853.1| 310|Homo sapiens sirtuin type 5 protein.
Length = 310
Score = 166 bits (404), Expect = 8e-41
Identities = 88/223 (39%), Positives = 123/223 (55%)
Frame = +1
Query: 208 SSDFSKFRVALKSAKEIVILSGAGISAESGIPTFRGAGGLWEEISSFGLSNXRSF*RKSK 387
SS + FR AK IVI+SGAG+SAESG+PTFRGAGG W + + L+ +F
Sbjct: 37 SSSMADFRKFFAKAKHIVIISGAGVSAESGVPTFRGAGGYWRKWQAQDLATPLAFAHNPS 96
Query: 388 LSMGILPLQKRGGQQRRKPNAGHFGYC*NSKXTMXFPKKITVITQNVGWVTCPEQETKRL 567
+R ++PNAGH +++ VITQN+ + + TK L
Sbjct: 97 RVWEFYHY-RREVMGSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELH-RKAGTKNL 154
Query: 568 IXLHXNLYQNSMYKCXEXLXNNDXPICXAXANRGAPXSNMVGSDIPVKLLPXCKKAHCGA 747
+ +H +L++ C N PIC A + +GAP + IPV+ LP C++A CG
Sbjct: 155 LEIHGSLFKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQDASIPVEKLPRCEEAGCGG 214
Query: 748 LLTPHIVWFXESLEHDILEAAEHAMSTCDVCLXVGTSSVXYPA 876
LL PH+VWF E+L+ ILE + ++ CD+CL VGTSSV YPA
Sbjct: 215 LLRPHVVWFGENLDPAILEEVDRELAHCDLCLVVGTSSVVYPA 257
>BC109320-1|AAI09321.1| 314|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 4 (S. cerevisiae)
protein.
Length = 314
Score = 46.4 bits (105), Expect = 1e-04
Identities = 53/219 (24%), Positives = 88/219 (40%), Gaps = 11/219 (5%)
Frame = +1
Query: 247 AKEIVILSGAGISAESGIPTFRGAG-GLWEEISSFGLSNXRSF*RKSKLSMGILPLQKRG 423
+K +++++GAGIS ESGIP +R GL+ + + F R + + G
Sbjct: 54 SKRLLVMTGAGISTESGIPDYRSEKVGLYARTDRRPIQHG-DFVRSAPIRQRYWARNFVG 112
Query: 424 GQQ--RRKPNAGHFGYC*NSKXTMXFPKKITVITQNVGWVTCPEQETKRLIXLHXNLYQN 597
Q +PN H+ K K ++TQNV + ++RL LH + +
Sbjct: 113 WPQFSSHQPNPAHWALSTWEK----LGKLYWLVTQNVD-ALHTKAGSRRLTELHGCMDRV 167
Query: 598 SMYKCXEXLXNND--------XPICXAXANRGAPXSNMVGSDIPVKLLPXCKKAHCGALL 753
C E P A A+ AP ++ S+ V+ CG L
Sbjct: 168 LCLDCGEQTPRGVLQERFQVLNPTWSAEAHGLAPDGDVFLSEEQVRSFQVPTCVQCGGHL 227
Query: 754 TPHIVWFXESLEHDILEAAEHAMSTCDVCLXVGTSSVXY 870
P +V+F +++ D ++ + D L VG+S Y
Sbjct: 228 KPDVVFFGDTVNPDKVDFVHKRVKEADSLLVVGSSLQVY 266
>BC109319-1|AAI09320.1| 314|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 4 (S. cerevisiae)
protein.
Length = 314
Score = 46.4 bits (105), Expect = 1e-04
Identities = 53/219 (24%), Positives = 88/219 (40%), Gaps = 11/219 (5%)
Frame = +1
Query: 247 AKEIVILSGAGISAESGIPTFRGAG-GLWEEISSFGLSNXRSF*RKSKLSMGILPLQKRG 423
+K +++++GAGIS ESGIP +R GL+ + + F R + + G
Sbjct: 54 SKRLLVMTGAGISTESGIPDYRSEKVGLYARTDRRPIQHG-DFVRSAPIRQRYWARNFVG 112
Query: 424 GQQ--RRKPNAGHFGYC*NSKXTMXFPKKITVITQNVGWVTCPEQETKRLIXLHXNLYQN 597
Q +PN H+ K K ++TQNV + ++RL LH + +
Sbjct: 113 WPQFSSHQPNPAHWALSTWEK----LGKLYWLVTQNVD-ALHTKAGSRRLTELHGCMDRV 167
Query: 598 SMYKCXEXLXNND--------XPICXAXANRGAPXSNMVGSDIPVKLLPXCKKAHCGALL 753
C E P A A+ AP ++ S+ V+ CG L
Sbjct: 168 LCLDCGEQTPRGVLQERFQVLNPTWSAEAHGLAPDGDVFLSEEQVRSFQVPTCVQCGGHL 227
Query: 754 TPHIVWFXESLEHDILEAAEHAMSTCDVCLXVGTSSVXY 870
P +V+F +++ D ++ + D L VG+S Y
Sbjct: 228 KPDVVFFGDTVNPDKVDFVHKRVKEADSLLVVGSSLQVY 266
>AF083109-1|AAD40852.1| 314|Homo sapiens sirtuin type 4 protein.
Length = 314
Score = 46.4 bits (105), Expect = 1e-04
Identities = 53/219 (24%), Positives = 88/219 (40%), Gaps = 11/219 (5%)
Frame = +1
Query: 247 AKEIVILSGAGISAESGIPTFRGAG-GLWEEISSFGLSNXRSF*RKSKLSMGILPLQKRG 423
+K +++++GAGIS ESGIP +R GL+ + + F R + + G
Sbjct: 54 SKRLLVMTGAGISTESGIPDYRSEKVGLYARTDRRPIQHG-DFVRSAPIRQRYWARNFVG 112
Query: 424 GQQ--RRKPNAGHFGYC*NSKXTMXFPKKITVITQNVGWVTCPEQETKRLIXLHXNLYQN 597
Q +PN H+ K K ++TQNV + ++RL LH + +
Sbjct: 113 WPQFSSHQPNPAHWALSTWEK----LGKLYWLVTQNVD-ALHTKAGSRRLTELHGCMDRV 167
Query: 598 SMYKCXEXLXNND--------XPICXAXANRGAPXSNMVGSDIPVKLLPXCKKAHCGALL 753
C E P A A+ AP ++ S+ V+ CG L
Sbjct: 168 LCLDCGEQTPRGVLQERFQVLNPTWSAEAHGLAPDGDVFLSEEQVRSFQVPTCVQCGGHL 227
Query: 754 TPHIVWFXESLEHDILEAAEHAMSTCDVCLXVGTSSVXY 870
P +V+F +++ D ++ + D L VG+S Y
Sbjct: 228 KPDVVFFGDTVNPDKVDFVHKRVKEADSLLVVGSSLQVY 266
>BC101793-1|AAI01794.1| 400|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 7 (S. cerevisiae)
protein.
Length = 400
Score = 39.9 bits (89), Expect = 0.012
Identities = 15/32 (46%), Positives = 24/32 (75%)
Frame = +1
Query: 235 ALKSAKEIVILSGAGISAESGIPTFRGAGGLW 330
A+++AK +V+ +GAGIS + IP +RG G+W
Sbjct: 95 AVRNAKYLVVYTGAGISTAASIPDYRGPNGVW 126
>BC101791-1|AAI01792.1| 400|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 7 (S. cerevisiae)
protein.
Length = 400
Score = 39.9 bits (89), Expect = 0.012
Identities = 15/32 (46%), Positives = 24/32 (75%)
Frame = +1
Query: 235 ALKSAKEIVILSGAGISAESGIPTFRGAGGLW 330
A+++AK +V+ +GAGIS + IP +RG G+W
Sbjct: 95 AVRNAKYLVVYTGAGISTAASIPDYRGPNGVW 126
>BC017305-1|AAH17305.1| 400|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 7 (S. cerevisiae)
protein.
Length = 400
Score = 39.9 bits (89), Expect = 0.012
Identities = 15/32 (46%), Positives = 24/32 (75%)
Frame = +1
Query: 235 ALKSAKEIVILSGAGISAESGIPTFRGAGGLW 330
A+++AK +V+ +GAGIS + IP +RG G+W
Sbjct: 95 AVRNAKYLVVYTGAGISTAASIPDYRGPNGVW 126
>AK002027-1|BAA92044.1| 183|Homo sapiens protein ( Homo sapiens
cDNA FLJ11165 fis, clone PLACE1007238. ).
Length = 183
Score = 39.9 bits (89), Expect = 0.012
Identities = 15/32 (46%), Positives = 24/32 (75%)
Frame = +1
Query: 235 ALKSAKEIVILSGAGISAESGIPTFRGAGGLW 330
A+++AK +V+ +GAGIS + IP +RG G+W
Sbjct: 95 AVRNAKYLVVYTGAGISTAASIPDYRGPNGVW 126
>AF233395-1|AAF43431.1| 400|Homo sapiens sir2-related protein type
7 protein.
Length = 400
Score = 39.9 bits (89), Expect = 0.012
Identities = 15/32 (46%), Positives = 24/32 (75%)
Frame = +1
Query: 235 ALKSAKEIVILSGAGISAESGIPTFRGAGGLW 330
A+++AK +V+ +GAGIS + IP +RG G+W
Sbjct: 95 AVRNAKYLVVYTGAGISTAASIPDYRGPNGVW 126
>DQ278604-1|ABB72675.1| 747|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 1 (S. cerevisiae)
protein.
Length = 747
Score = 38.3 bits (85), Expect = 0.036
Identities = 14/35 (40%), Positives = 24/35 (68%)
Frame = +1
Query: 238 LKSAKEIVILSGAGISAESGIPTFRGAGGLWEEIS 342
L+ K+I++L+GAG+S GIP FR G++ ++
Sbjct: 250 LQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLA 284
>BC012499-1|AAH12499.1| 555|Homo sapiens SIRT1 protein protein.
Length = 555
Score = 38.3 bits (85), Expect = 0.036
Identities = 14/35 (40%), Positives = 24/35 (68%)
Frame = +1
Query: 238 LKSAKEIVILSGAGISAESGIPTFRGAGGLWEEIS 342
L+ K+I++L+GAG+S GIP FR G++ ++
Sbjct: 58 LQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLA 92
>AL133551-8|CAI16036.1| 747|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 1 (S. cerevisiae)
protein.
Length = 747
Score = 38.3 bits (85), Expect = 0.036
Identities = 14/35 (40%), Positives = 24/35 (68%)
Frame = +1
Query: 238 LKSAKEIVILSGAGISAESGIPTFRGAGGLWEEIS 342
L+ K+I++L+GAG+S GIP FR G++ ++
Sbjct: 250 LQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLA 284
>AF235040-1|AAG38486.1| 747|Homo sapiens SIR2alpha protein protein.
Length = 747
Score = 38.3 bits (85), Expect = 0.036
Identities = 14/35 (40%), Positives = 24/35 (68%)
Frame = +1
Query: 238 LKSAKEIVILSGAGISAESGIPTFRGAGGLWEEIS 342
L+ K+I++L+GAG+S GIP FR G++ ++
Sbjct: 250 LQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLA 284
>AF083106-1|AAD40849.2| 747|Homo sapiens sirtuin type 1 protein.
Length = 747
Score = 38.3 bits (85), Expect = 0.036
Identities = 14/35 (40%), Positives = 24/35 (68%)
Frame = +1
Query: 238 LKSAKEIVILSGAGISAESGIPTFRGAGGLWEEIS 342
L+ K+I++L+GAG+S GIP FR G++ ++
Sbjct: 250 LQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLA 284
>CR457200-1|CAG33481.1| 355|Homo sapiens SIRT6 protein.
Length = 355
Score = 37.9 bits (84), Expect = 0.048
Identities = 15/31 (48%), Positives = 21/31 (67%)
Frame = +1
Query: 238 LKSAKEIVILSGAGISAESGIPTFRGAGGLW 330
++ + +V +GAGIS SGIP FRG G+W
Sbjct: 41 VRQSSSVVFHTGAGISTASGIPDFRGPHGVW 71
>BC001042-1|AAH01042.1| 399|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 3 (S. cerevisiae)
protein.
Length = 399
Score = 37.5 bits (83), Expect = 0.063
Identities = 16/42 (38%), Positives = 26/42 (61%), Gaps = 1/42 (2%)
Frame = +1
Query: 232 VALKSAKEIVILSGAGISAESGIPTFRGAG-GLWEEISSFGL 354
+ ++ + +V++ GAGIS SGIP FR G GL+ + + L
Sbjct: 132 IRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDL 173
>AF083108-1|AAD40851.1| 399|Homo sapiens sirtuin type 3 protein.
Length = 399
Score = 37.5 bits (83), Expect = 0.063
Identities = 16/42 (38%), Positives = 26/42 (61%), Gaps = 1/42 (2%)
Frame = +1
Query: 232 VALKSAKEIVILSGAGISAESGIPTFRGAG-GLWEEISSFGL 354
+ ++ + +V++ GAGIS SGIP FR G GL+ + + L
Sbjct: 132 IRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDL 173
>AC003982-1|AAB95634.1| 326|Homo sapiens WUGSC:H_166H1.1 protein.
Length = 326
Score = 37.1 bits (82), Expect = 0.084
Identities = 53/231 (22%), Positives = 90/231 (38%), Gaps = 23/231 (9%)
Frame = +1
Query: 247 AKEIVILSGAGISAESGIPTFRGAG-GLWEEISSFGLSNXRSF*RKSKLSMGILPLQKRG 423
+K +++++GAGIS ESGIP +R GL+ + + F R + + G
Sbjct: 54 SKRLLVMTGAGISTESGIPDYRSEKVGLYARTDRRPIQHG-DFVRSAPIRQRYWARNFVG 112
Query: 424 GQQ--RRKPNAGHFGYC*NSKXTMXFPKKITVITQNVGWVTCPEQETKRLIXLH------ 579
Q +PN H+ K K ++TQNV + ++RL LH
Sbjct: 113 WPQFSSHQPNPAHWALSTWEK----LGKLYWLVTQNVD-ALHTKAGSRRLTELHGCMDRA 167
Query: 580 ---XNLYQNSMYKCXEXLXNND-----------XPICXAXANRGAPXSNMVGSDIPVKLL 717
+++ S C + P A A+ AP ++ S+ V+
Sbjct: 168 YCSVSVFLGSRVLCLDCGEQTPRGVLQERFQVLNPTWSAEAHGLAPDGDVFLSEEQVRSF 227
Query: 718 PXCKKAHCGALLTPHIVWFXESLEHDILEAAEHAMSTCDVCLXVGTSSVXY 870
CG L P +V+F +++ D ++ + D L VG+S Y
Sbjct: 228 QVPTCVQCGGHLKPDVVFFGDTVNPDKVDFVHKRVKEADSLLVVGSSLQVY 278
>BC028220-1|AAH28220.1| 328|Homo sapiens SIRT6 protein protein.
Length = 328
Score = 36.7 bits (81), Expect = 0.11
Identities = 15/28 (53%), Positives = 19/28 (67%)
Frame = +1
Query: 247 AKEIVILSGAGISAESGIPTFRGAGGLW 330
+ +V +GAGIS SGIP FRG G+W
Sbjct: 44 SSNVVFHTGAGISTASGIPDFRGPHGVW 71
>BC005026-1|AAH05026.1| 355|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 6 (S. cerevisiae)
protein.
Length = 355
Score = 36.7 bits (81), Expect = 0.11
Identities = 15/28 (53%), Positives = 19/28 (67%)
Frame = +1
Query: 247 AKEIVILSGAGISAESGIPTFRGAGGLW 330
+ +V +GAGIS SGIP FRG G+W
Sbjct: 44 SSSVVFHTGAGISTASGIPDFRGPHGVW 71
>AK074810-1|BAC11222.1| 355|Homo sapiens protein ( Homo sapiens
cDNA FLJ90329 fis, clone NT2RP2001948, weakly similar to
HST2 PROTEIN. ).
Length = 355
Score = 36.7 bits (81), Expect = 0.11
Identities = 15/28 (53%), Positives = 19/28 (67%)
Frame = +1
Query: 247 AKEIVILSGAGISAESGIPTFRGAGGLW 330
+ +V +GAGIS SGIP FRG G+W
Sbjct: 44 SSNVVFHTGAGISTASGIPDFRGPHGVW 71
>AF233396-1|AAF43432.1| 355|Homo sapiens sir2-related protein type
6 protein.
Length = 355
Score = 36.7 bits (81), Expect = 0.11
Identities = 15/28 (53%), Positives = 19/28 (67%)
Frame = +1
Query: 247 AKEIVILSGAGISAESGIPTFRGAGGLW 330
+ +V +GAGIS SGIP FRG G+W
Sbjct: 44 SSSVVFHTGAGISTASGIPDFRGPHGVW 71
>AC006930-1|AAD15478.1| 377|Homo sapiens R33423_1 protein.
Length = 377
Score = 36.7 bits (81), Expect = 0.11
Identities = 15/28 (53%), Positives = 19/28 (67%)
Frame = +1
Query: 247 AKEIVILSGAGISAESGIPTFRGAGGLW 330
+ +V +GAGIS SGIP FRG G+W
Sbjct: 44 SSSVVFHTGAGISTASGIPDFRGPHGVW 71
>BC003547-1|AAH03547.1| 352|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 2 (S. cerevisiae)
protein.
Length = 352
Score = 33.5 bits (73), Expect = 1.0
Identities = 48/213 (22%), Positives = 81/213 (38%), Gaps = 5/213 (2%)
Frame = +1
Query: 250 KEIVILSGAGISAESGIPTFRG-AGGLWEEISSFGLSNXRSF*RKS---KLSMGILPLQK 417
+ ++ L GAGIS +GIP FR + GL++ + + L + S K L K
Sbjct: 40 RRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAK 99
Query: 418 RGGQQRRKPNAGHFGYC*NSKXTMXFPKKITVITQNVGWV-TCPEQETKRLIXLHXNLYQ 594
+ KP H+ + + TQN+ + E + L+ H Y
Sbjct: 100 ELYPGQFKPTICHY----FMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYT 155
Query: 595 NSMYKCXEXLXNNDXPICXAXANRGAPXSNMVGSDIPVKLLPXCKKAHCGALLTPHIVWF 774
+ C ++ P+ + + I ++ P C+ C +L+ P IV+F
Sbjct: 156 S---HCVSASCRHEYPL------------SWMKEKIFSEVTPKCE--DCQSLVKPDIVFF 198
Query: 775 XESLEHDILEAAEHAMSTCDVCLXVGTSSVXYP 873
ESL + D+ L +GTS P
Sbjct: 199 GESLPARFFSCMQSDFLKVDLLLVMGTSLQVQP 231
>BC003012-1|AAH03012.1| 352|Homo sapiens sirtuin (silent mating
type information regulation 2 homolog) 2 (S. cerevisiae)
protein.
Length = 352
Score = 33.5 bits (73), Expect = 1.0
Identities = 48/213 (22%), Positives = 81/213 (38%), Gaps = 5/213 (2%)
Frame = +1
Query: 250 KEIVILSGAGISAESGIPTFRG-AGGLWEEISSFGLSNXRSF*RKS---KLSMGILPLQK 417
+ ++ L GAGIS +GIP FR + GL++ + + L + S K L K
Sbjct: 40 RRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAK 99
Query: 418 RGGQQRRKPNAGHFGYC*NSKXTMXFPKKITVITQNVGWV-TCPEQETKRLIXLHXNLYQ 594
+ KP H+ + + TQN+ + E + L+ H Y
Sbjct: 100 ELYPGQFKPTICHY----FMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYT 155
Query: 595 NSMYKCXEXLXNNDXPICXAXANRGAPXSNMVGSDIPVKLLPXCKKAHCGALLTPHIVWF 774
+ C ++ P+ + + I ++ P C+ C +L+ P IV+F
Sbjct: 156 S---HCVSASCRHEYPL------------SWMKEKIFSEVTPKCE--DCQSLVKPDIVFF 198
Query: 775 XESLEHDILEAAEHAMSTCDVCLXVGTSSVXYP 873
ESL + D+ L +GTS P
Sbjct: 199 GESLPARFFSCMQSDFLKVDLLLVMGTSLQVQP 231
>AY030277-1|AAK51133.1| 352|Homo sapiens SIRT2 protein.
Length = 352
Score = 33.5 bits (73), Expect = 1.0
Identities = 48/213 (22%), Positives = 81/213 (38%), Gaps = 5/213 (2%)
Frame = +1
Query: 250 KEIVILSGAGISAESGIPTFRG-AGGLWEEISSFGLSNXRSF*RKS---KLSMGILPLQK 417
+ ++ L GAGIS +GIP FR + GL++ + + L + S K L K
Sbjct: 40 RRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAK 99
Query: 418 RGGQQRRKPNAGHFGYC*NSKXTMXFPKKITVITQNVGWV-TCPEQETKRLIXLHXNLYQ 594
+ KP H+ + + TQN+ + E + L+ H Y
Sbjct: 100 ELYPGQFKPTICHY----FMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYT 155
Query: 595 NSMYKCXEXLXNNDXPICXAXANRGAPXSNMVGSDIPVKLLPXCKKAHCGALLTPHIVWF 774
+ C ++ P+ + + I ++ P C+ C +L+ P IV+F
Sbjct: 156 S---HCVSASCRHEYPL------------SWMKEKIFSEVTPKCE--DCQSLVKPDIVFF 198
Query: 775 XESLEHDILEAAEHAMSTCDVCLXVGTSSVXYP 873
ESL + D+ L +GTS P
Sbjct: 199 GESLPARFFSCMQSDFLKVDLLLVMGTSLQVQP 231
>AF095714-1|AAD45971.1| 352|Homo sapiens silencing information
regulator 2-like protein protein.
Length = 352
Score = 33.5 bits (73), Expect = 1.0
Identities = 48/213 (22%), Positives = 81/213 (38%), Gaps = 5/213 (2%)
Frame = +1
Query: 250 KEIVILSGAGISAESGIPTFRG-AGGLWEEISSFGLSNXRSF*RKS---KLSMGILPLQK 417
+ ++ L GAGIS +GIP FR + GL++ + + L + S K L K
Sbjct: 40 RRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAK 99
Query: 418 RGGQQRRKPNAGHFGYC*NSKXTMXFPKKITVITQNVGWV-TCPEQETKRLIXLHXNLYQ 594
+ KP H+ + + TQN+ + E + L+ H Y
Sbjct: 100 ELYPGQFKPTICHY----FMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYT 155
Query: 595 NSMYKCXEXLXNNDXPICXAXANRGAPXSNMVGSDIPVKLLPXCKKAHCGALLTPHIVWF 774
+ C ++ P+ + + I ++ P C+ C +L+ P IV+F
Sbjct: 156 S---HCVSASCRHEYPL------------SWMKEKIFSEVTPKCE--DCQSLVKPDIVFF 198
Query: 775 XESLEHDILEAAEHAMSTCDVCLXVGTSSVXYP 873
ESL + D+ L +GTS P
Sbjct: 199 GESLPARFFSCMQSDFLKVDLLLVMGTSLQVQP 231
>AF083107-1|AAD40850.2| 389|Homo sapiens sirtuin type 2 protein.
Length = 389
Score = 33.5 bits (73), Expect = 1.0
Identities = 48/213 (22%), Positives = 81/213 (38%), Gaps = 5/213 (2%)
Frame = +1
Query: 250 KEIVILSGAGISAESGIPTFRG-AGGLWEEISSFGLSNXRSF*RKS---KLSMGILPLQK 417
+ ++ L GAGIS +GIP FR + GL++ + + L + S K L K
Sbjct: 77 RRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAK 136
Query: 418 RGGQQRRKPNAGHFGYC*NSKXTMXFPKKITVITQNVGWV-TCPEQETKRLIXLHXNLYQ 594
+ KP H+ + + TQN+ + E + L+ H Y
Sbjct: 137 ELYPGQFKPTICHY----FMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYT 192
Query: 595 NSMYKCXEXLXNNDXPICXAXANRGAPXSNMVGSDIPVKLLPXCKKAHCGALLTPHIVWF 774
+ C ++ P+ + + I ++ P C+ C +L+ P IV+F
Sbjct: 193 S---HCVSASCRHEYPL------------SWMKEKIFSEVTPKCE--DCQSLVKPDIVFF 235
Query: 775 XESLEHDILEAAEHAMSTCDVCLXVGTSSVXYP 873
ESL + D+ L +GTS P
Sbjct: 236 GESLPARFFSCMQSDFLKVDLLLVMGTSLQVQP 268
>AF131800-1|AAD20046.1| 254|Homo sapiens Similar to rat 5E5 antigen
protein.
Length = 254
Score = 33.1 bits (72), Expect = 1.4
Identities = 47/208 (22%), Positives = 80/208 (38%), Gaps = 5/208 (2%)
Frame = +1
Query: 250 KEIVILSGAGISAESGIPTFRG-AGGLWEEISSFGLSNXRSF*RKS---KLSMGILPLQK 417
+ ++ L GAGIS +GIP FR + GL++ + + L + S K L K
Sbjct: 60 RRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAK 119
Query: 418 RGGQQRRKPNAGHFGYC*NSKXTMXFPKKITVITQNVGWV-TCPEQETKRLIXLHXNLYQ 594
+ KP H+ + + TQN+ + E + L+ H Y
Sbjct: 120 ELYPGQFKPTICHY----FMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYT 175
Query: 595 NSMYKCXEXLXNNDXPICXAXANRGAPXSNMVGSDIPVKLLPXCKKAHCGALLTPHIVWF 774
+ C ++ P+ + + I ++ P C+ C +L+ P IV+F
Sbjct: 176 S---HCVSASCRHEYPL------------SWMKEKIFSEVTPKCE--DCQSLVKPDIVFF 218
Query: 775 XESLEHDILEAAEHAMSTCDVCLXVGTS 858
ESL + D+ L +GTS
Sbjct: 219 GESLPARFFSCMQSDFLKVDLLLVMGTS 246
>AJ505014-1|CAD43717.1| 369|Homo sapiens sirtuin type 2 protein.
Length = 369
Score = 32.7 bits (71), Expect = 1.8
Identities = 48/213 (22%), Positives = 81/213 (38%), Gaps = 5/213 (2%)
Frame = +1
Query: 250 KEIVILSGAGISAESGIPTFRG-AGGLWEEISSFGLSNXRSF*RKS---KLSMGILPLQK 417
+ ++ L GAGIS +GIP FR + GL++ + + L + S K L K
Sbjct: 57 RRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAK 116
Query: 418 RGGQQRRKPNAGHFGYC*NSKXTMXFPKKITVITQNVGWV-TCPEQETKRLIXLHXNLYQ 594
+ KP H+ + + TQN+ + E + L+ H Y
Sbjct: 117 ELYPGQFKPTICHY----FMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYT 172
Query: 595 NSMYKCXEXLXNNDXPICXAXANRGAPXSNMVGSDIPVKLLPXCKKAHCGALLTPHIVWF 774
+ C ++ P+ + S++ +K C+ C +L+ P IV+F
Sbjct: 173 S---HCVSASCRHEYPLSW--------MKEKIFSEVTLK----CE--DCQSLVKPDIVFF 215
Query: 775 XESLEHDILEAAEHAMSTCDVCLXVGTSSVXYP 873
ESL + D+ L +GTS P
Sbjct: 216 GESLPARFFSCMQSDFLKVDLLLVMGTSLQVQP 248
>AF160214-1|AAF67015.1| 373|Homo sapiens silent information
regulator 2 homolog protein.
Length = 373
Score = 32.3 bits (70), Expect = 2.4
Identities = 14/36 (38%), Positives = 23/36 (63%), Gaps = 1/36 (2%)
Frame = +1
Query: 250 KEIVILSGAGISAESGIPTFRG-AGGLWEEISSFGL 354
+ ++ L GAGIS +GIP FR + GL++ + + L
Sbjct: 61 RRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHL 96
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 105,932,249
Number of Sequences: 237096
Number of extensions: 1908995
Number of successful extensions: 2932
Number of sequences better than 10.0: 35
Number of HSP's better than 10.0 without gapping: 2852
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2922
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11215125244
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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