Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP15_F_N15
(892 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein. 138 2e-32
M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein. 138 2e-32
M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein. 138 2e-32
CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein. 138 2e-32
BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal ... 138 2e-32
BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal ... 138 2e-32
BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein. 138 2e-32
BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic pepti... 122 2e-27
AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4 pro... 122 2e-27
AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor prot... 122 2e-27
AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein. 122 2e-27
M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein. 117 5e-26
J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein. 117 5e-26
BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein. 117 5e-26
BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein. 117 5e-26
BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein. 117 5e-26
AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein. 117 5e-26
AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternativ... 117 5e-26
X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mR... 107 4e-23
M10152-1|AAD03461.1| 406|Homo sapiens renin protein. 107 4e-23
L00073-1|AAA60363.1| 406|Homo sapiens renin protein. 107 4e-23
CR536498-1|CAG38737.1| 406|Homo sapiens REN protein. 107 4e-23
BC047752-1|AAH47752.1| 406|Homo sapiens renin protein. 107 4e-23
BC033474-1|AAH33474.1| 406|Homo sapiens renin protein. 107 4e-23
AL592146-1|CAI16594.1| 406|Homo sapiens renin protein. 107 4e-23
AL592114-1|CAH71224.1| 406|Homo sapiens renin protein. 107 4e-23
M26901-1|AAA60364.1| 403|Homo sapiens renin protein. 105 2e-22
BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein. 105 2e-22
AY436324-1|AAR03502.1| 403|Homo sapiens renin protein. 105 2e-22
AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3 pro... 105 2e-22
U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein. 101 4e-21
M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein. 101 4e-21
M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein. 101 4e-21
J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein. 101 4e-21
BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinog... 101 4e-21
AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinog... 101 4e-21
M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein. 91 4e-18
J00287-1|AAA98529.1| 388|Homo sapiens PEP protein. 91 4e-18
BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I (... 91 4e-18
BC042578-1|AAH42578.1| 104|Homo sapiens PGC protein protein. 60 1e-08
AL365205-2|CAI95135.1| 140|Homo sapiens progastricsin (pepsinog... 59 2e-08
AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens ... 52 2e-06
BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving ... 51 6e-06
AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein. 51 6e-06
AL163285-1|CAB90554.1| 415|Homo sapiens beta-site APP-cleaving ... 51 6e-06
AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein. 51 6e-06
AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic ... 51 6e-06
AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1 pro... 51 6e-06
AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein. 51 6e-06
AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein. 51 6e-06
AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein. 51 6e-06
AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein. 51 6e-06
AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease ... 51 6e-06
AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein. 51 6e-06
DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving ... 48 6e-05
BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving ... 48 6e-05
AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic ... 48 6e-05
AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase prot... 48 6e-05
AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2 pro... 48 6e-05
AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein. 48 6e-05
AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving ... 48 6e-05
AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein. 48 6e-05
BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving ... 45 3e-04
AB177847-1|BAD66825.1| 396|Homo sapiens KIAA1149 splice variant... 42 0.004
AL365205-3|CAM16152.1| 86|Homo sapiens progastricsin (pepsinog... 39 0.028
AF338816-1|AAK38374.1| 476|Homo sapiens beta-site APP cleaving ... 36 0.15
AB050436-1|BAB40931.1| 476|Homo sapiens beta-site APP cleaving ... 36 0.15
AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving ... 35 0.46
AB089958-1|BAC81826.1| 127|Homo sapiens beta-site APP cleaving ... 35 0.46
AB050438-1|BAB40933.1| 432|Homo sapiens beta-site APP cleaving ... 35 0.46
AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving ... 35 0.46
AK055141-1|BAB70862.1| 260|Homo sapiens protein ( Homo sapiens ... 33 1.8
AF141344-1|AAG49447.1| 119|Homo sapiens LYST-interacting protei... 32 2.4
AK056774-1|BAB71280.1| 256|Homo sapiens protein ( Homo sapiens ... 31 4.2
BC041063-1|AAH41063.1| 616|Homo sapiens eyes absent homolog 4 (... 31 7.4
BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain cont... 31 7.4
AL450270-3|CAI41273.1| 605|Homo sapiens eyes absent homolog 4 (... 31 7.4
AL450270-2|CAI41272.1| 639|Homo sapiens eyes absent homolog 4 (... 31 7.4
AL121959-1|CAB92069.2| 639|Homo sapiens eyes absent homolog 4 (... 31 7.4
AL024497-3|CAI42525.1| 605|Homo sapiens eyes absent homolog 4 (... 31 7.4
AL024497-2|CAI42524.1| 639|Homo sapiens eyes absent homolog 4 (... 31 7.4
>X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 138 bits (334), Expect = 2e-32
Identities = 70/119 (58%), Positives = 87/119 (73%), Gaps = 12/119 (10%)
Frame = +3
Query: 489 LHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV-----------GGLKVRRQT 635
+H+KY+S KS TYV NGT F I YGSGSLSG+LS D V+V GG+KV RQ
Sbjct: 119 IHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQV 178
Query: 636 FAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVXPVFDNMVAQGLV-QPVFSFYLNRDP 809
F EA +PG+ F+AAKFDGILGMA+ I+V++V PVFDN++ Q LV Q +FSFYL+RDP
Sbjct: 179 FGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDP 237
Score = 104 bits (250), Expect = 4e-22
Identities = 56/108 (51%), Positives = 66/108 (61%), Gaps = 11/108 (10%)
Frame = +2
Query: 197 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 343
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 344 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACF 487
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC+
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACW 118
>M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 138 bits (334), Expect = 2e-32
Identities = 70/119 (58%), Positives = 87/119 (73%), Gaps = 12/119 (10%)
Frame = +3
Query: 489 LHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV-----------GGLKVRRQT 635
+H+KY+S KS TYV NGT F I YGSGSLSG+LS D V+V GG+KV RQ
Sbjct: 119 IHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQV 178
Query: 636 FAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVXPVFDNMVAQGLV-QPVFSFYLNRDP 809
F EA +PG+ F+AAKFDGILGMA+ I+V++V PVFDN++ Q LV Q +FSFYL+RDP
Sbjct: 179 FGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDP 237
Score = 104 bits (250), Expect = 4e-22
Identities = 56/108 (51%), Positives = 66/108 (61%), Gaps = 11/108 (10%)
Frame = +2
Query: 197 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 343
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 344 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACF 487
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC+
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACW 118
>M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 138 bits (334), Expect = 2e-32
Identities = 70/119 (58%), Positives = 87/119 (73%), Gaps = 12/119 (10%)
Frame = +3
Query: 489 LHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV-----------GGLKVRRQT 635
+H+KY+S KS TYV NGT F I YGSGSLSG+LS D V+V GG+KV RQ
Sbjct: 119 IHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQV 178
Query: 636 FAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVXPVFDNMVAQGLV-QPVFSFYLNRDP 809
F EA +PG+ F+AAKFDGILGMA+ I+V++V PVFDN++ Q LV Q +FSFYL+RDP
Sbjct: 179 FGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDP 237
Score = 104 bits (250), Expect = 4e-22
Identities = 56/108 (51%), Positives = 66/108 (61%), Gaps = 11/108 (10%)
Frame = +2
Query: 197 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 343
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 344 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACF 487
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC+
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACW 118
>CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 138 bits (334), Expect = 2e-32
Identities = 70/119 (58%), Positives = 87/119 (73%), Gaps = 12/119 (10%)
Frame = +3
Query: 489 LHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV-----------GGLKVRRQT 635
+H+KY+S KS TYV NGT F I YGSGSLSG+LS D V+V GG+KV RQ
Sbjct: 119 IHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQV 178
Query: 636 FAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVXPVFDNMVAQGLV-QPVFSFYLNRDP 809
F EA +PG+ F+AAKFDGILGMA+ I+V++V PVFDN++ Q LV Q +FSFYL+RDP
Sbjct: 179 FGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDP 237
Score = 104 bits (250), Expect = 4e-22
Identities = 56/108 (51%), Positives = 66/108 (61%), Gaps = 11/108 (10%)
Frame = +2
Query: 197 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 343
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 344 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACF 487
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC+
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACW 118
>BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 138 bits (334), Expect = 2e-32
Identities = 70/119 (58%), Positives = 87/119 (73%), Gaps = 12/119 (10%)
Frame = +3
Query: 489 LHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV-----------GGLKVRRQT 635
+H+KY+S KS TYV NGT F I YGSGSLSG+LS D V+V GG+KV RQ
Sbjct: 119 IHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQV 178
Query: 636 FAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVXPVFDNMVAQGLV-QPVFSFYLNRDP 809
F EA +PG+ F+AAKFDGILGMA+ I+V++V PVFDN++ Q LV Q +FSFYL+RDP
Sbjct: 179 FGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDP 237
Score = 104 bits (250), Expect = 4e-22
Identities = 56/108 (51%), Positives = 66/108 (61%), Gaps = 11/108 (10%)
Frame = +2
Query: 197 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 343
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 344 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACF 487
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC+
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACW 118
>BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 138 bits (334), Expect = 2e-32
Identities = 70/119 (58%), Positives = 87/119 (73%), Gaps = 12/119 (10%)
Frame = +3
Query: 489 LHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV-----------GGLKVRRQT 635
+H+KY+S KS TYV NGT F I YGSGSLSG+LS D V+V GG+KV RQ
Sbjct: 119 IHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQV 178
Query: 636 FAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVXPVFDNMVAQGLV-QPVFSFYLNRDP 809
F EA +PG+ F+AAKFDGILGMA+ I+V++V PVFDN++ Q LV Q +FSFYL+RDP
Sbjct: 179 FGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDP 237
Score = 104 bits (250), Expect = 4e-22
Identities = 56/108 (51%), Positives = 66/108 (61%), Gaps = 11/108 (10%)
Frame = +2
Query: 197 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 343
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 344 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACF 487
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC+
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACW 118
>BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 138 bits (334), Expect = 2e-32
Identities = 70/119 (58%), Positives = 87/119 (73%), Gaps = 12/119 (10%)
Frame = +3
Query: 489 LHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV-----------GGLKVRRQT 635
+H+KY+S KS TYV NGT F I YGSGSLSG+LS D V+V GG+KV RQ
Sbjct: 119 IHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQV 178
Query: 636 FAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVXPVFDNMVAQGLV-QPVFSFYLNRDP 809
F EA +PG+ F+AAKFDGILGMA+ I+V++V PVFDN++ Q LV Q +FSFYL+RDP
Sbjct: 179 FGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDP 237
Score = 104 bits (250), Expect = 4e-22
Identities = 56/108 (51%), Positives = 66/108 (61%), Gaps = 11/108 (10%)
Frame = +2
Query: 197 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 343
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 344 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACF 487
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC+
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACW 118
>BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic
peptidase protein.
Length = 420
Score = 122 bits (294), Expect = 2e-27
Identities = 57/108 (52%), Positives = 77/108 (71%), Gaps = 1/108 (0%)
Frame = +3
Query: 489 LHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLA 668
LH+++D + S ++ ANGT+FAIQYG+G + G LS D +T+GG+K F EA+ EP L
Sbjct: 118 LHHRFDPKASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLV 177
Query: 669 FVAAKFDGILGMAFSTIAVDHVXPVFDNMVAQGLV-QPVFSFYLNRDP 809
F A FDGILG+ F ++V+ V P D +V QGL+ +PVFSFYLNRDP
Sbjct: 178 FAFAHFDGILGLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDP 225
Score = 91.9 bits (218), Expect = 3e-18
Identities = 45/99 (45%), Positives = 61/99 (61%), Gaps = 5/99 (5%)
Frame = +2
Query: 206 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 370
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRTLNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 371 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACF 487
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C+
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCW 117
>AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4
protein.
Length = 420
Score = 122 bits (294), Expect = 2e-27
Identities = 57/108 (52%), Positives = 77/108 (71%), Gaps = 1/108 (0%)
Frame = +3
Query: 489 LHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLA 668
LH+++D + S ++ ANGT+FAIQYG+G + G LS D +T+GG+K F EA+ EP L
Sbjct: 118 LHHRFDPKASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLV 177
Query: 669 FVAAKFDGILGMAFSTIAVDHVXPVFDNMVAQGLV-QPVFSFYLNRDP 809
F A FDGILG+ F ++V+ V P D +V QGL+ +PVFSFYLNRDP
Sbjct: 178 FAFAHFDGILGLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDP 225
Score = 91.5 bits (217), Expect = 4e-18
Identities = 45/99 (45%), Positives = 61/99 (61%), Gaps = 5/99 (5%)
Frame = +2
Query: 206 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 370
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 371 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACF 487
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C+
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCW 117
>AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor
protein.
Length = 420
Score = 122 bits (294), Expect = 2e-27
Identities = 57/108 (52%), Positives = 77/108 (71%), Gaps = 1/108 (0%)
Frame = +3
Query: 489 LHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLA 668
LH+++D + S ++ ANGT+FAIQYG+G + G LS D +T+GG+K F EA+ EP L
Sbjct: 118 LHHRFDPKASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLV 177
Query: 669 FVAAKFDGILGMAFSTIAVDHVXPVFDNMVAQGLV-QPVFSFYLNRDP 809
F A FDGILG+ F ++V+ V P D +V QGL+ +PVFSFYLNRDP
Sbjct: 178 FAFAHFDGILGLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDP 225
Score = 91.5 bits (217), Expect = 4e-18
Identities = 45/99 (45%), Positives = 61/99 (61%), Gaps = 5/99 (5%)
Frame = +2
Query: 206 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 370
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 371 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACF 487
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C+
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCW 117
>AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein.
Length = 420
Score = 122 bits (294), Expect = 2e-27
Identities = 57/108 (52%), Positives = 77/108 (71%), Gaps = 1/108 (0%)
Frame = +3
Query: 489 LHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLA 668
LH+++D + S ++ ANGT+FAIQYG+G + G LS D +T+GG+K F EA+ EP L
Sbjct: 118 LHHRFDPKASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLV 177
Query: 669 FVAAKFDGILGMAFSTIAVDHVXPVFDNMVAQGLV-QPVFSFYLNRDP 809
F A FDGILG+ F ++V+ V P D +V QGL+ +PVFSFYLNRDP
Sbjct: 178 FAFAHFDGILGLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDP 225
Score = 91.5 bits (217), Expect = 4e-18
Identities = 45/99 (45%), Positives = 61/99 (61%), Gaps = 5/99 (5%)
Frame = +2
Query: 206 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 370
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 371 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACF 487
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C+
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCW 117
>M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 117 bits (282), Expect = 5e-26
Identities = 56/109 (51%), Positives = 76/109 (69%), Gaps = 1/109 (0%)
Frame = +3
Query: 492 HNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 671
H+++ +S TY G F+IQYG+GSLSG + D V+V GL V Q F E+V+EPG F
Sbjct: 117 HSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTF 176
Query: 672 VAAKFDGILGMAFSTIAVDHVXPVFDNMVAQGLVQ-PVFSFYLNRDPGG 815
V A+FDGILG+ + ++AV V PVFDNM+AQ LV P+FS Y++ +P G
Sbjct: 177 VDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEG 225
Score = 77.4 bits (182), Expect = 7e-14
Identities = 46/109 (42%), Positives = 63/109 (57%), Gaps = 10/109 (9%)
Frame = +2
Query: 188 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 337
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 338 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 484
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPAC 114
>J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein.
Length = 396
Score = 117 bits (282), Expect = 5e-26
Identities = 56/109 (51%), Positives = 76/109 (69%), Gaps = 1/109 (0%)
Frame = +3
Query: 492 HNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 671
H+++ +S TY G F+IQYG+GSLSG + D V+V GL V Q F E+V+EPG F
Sbjct: 117 HSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTF 176
Query: 672 VAAKFDGILGMAFSTIAVDHVXPVFDNMVAQGLVQ-PVFSFYLNRDPGG 815
V A+FDGILG+ + ++AV V PVFDNM+AQ LV P+FS Y++ +P G
Sbjct: 177 VDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEG 225
Score = 77.4 bits (182), Expect = 7e-14
Identities = 46/109 (42%), Positives = 63/109 (57%), Gaps = 10/109 (9%)
Frame = +2
Query: 188 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 337
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 338 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 484
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPAC 114
>BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein.
Length = 363
Score = 117 bits (282), Expect = 5e-26
Identities = 56/109 (51%), Positives = 76/109 (69%), Gaps = 1/109 (0%)
Frame = +3
Query: 492 HNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 671
H+++ +S TY G F+IQYG+GSLSG + D V+V GL V Q F E+V+EPG F
Sbjct: 117 HSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTF 176
Query: 672 VAAKFDGILGMAFSTIAVDHVXPVFDNMVAQGLVQ-PVFSFYLNRDPGG 815
V A+FDGILG+ + ++AV V PVFDNM+AQ LV P+FS Y++ +P G
Sbjct: 177 VDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEG 225
Score = 77.4 bits (182), Expect = 7e-14
Identities = 46/109 (42%), Positives = 63/109 (57%), Gaps = 10/109 (9%)
Frame = +2
Query: 188 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 337
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 338 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 484
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPAC 114
>BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 117 bits (282), Expect = 5e-26
Identities = 56/109 (51%), Positives = 76/109 (69%), Gaps = 1/109 (0%)
Frame = +3
Query: 492 HNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 671
H+++ +S TY G F+IQYG+GSLSG + D V+V GL V Q F E+V+EPG F
Sbjct: 117 HSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTF 176
Query: 672 VAAKFDGILGMAFSTIAVDHVXPVFDNMVAQGLVQ-PVFSFYLNRDPGG 815
V A+FDGILG+ + ++AV V PVFDNM+AQ LV P+FS Y++ +P G
Sbjct: 177 VDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEG 225
Score = 77.4 bits (182), Expect = 7e-14
Identities = 46/109 (42%), Positives = 63/109 (57%), Gaps = 10/109 (9%)
Frame = +2
Query: 188 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 337
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 338 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 484
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPAC 114
>BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 117 bits (282), Expect = 5e-26
Identities = 56/109 (51%), Positives = 76/109 (69%), Gaps = 1/109 (0%)
Frame = +3
Query: 492 HNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 671
H+++ +S TY G F+IQYG+GSLSG + D V+V GL V Q F E+V+EPG F
Sbjct: 117 HSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTF 176
Query: 672 VAAKFDGILGMAFSTIAVDHVXPVFDNMVAQGLVQ-PVFSFYLNRDPGG 815
V A+FDGILG+ + ++AV V PVFDNM+AQ LV P+FS Y++ +P G
Sbjct: 177 VDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEG 225
Score = 77.4 bits (182), Expect = 7e-14
Identities = 46/109 (42%), Positives = 63/109 (57%), Gaps = 10/109 (9%)
Frame = +2
Query: 188 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 337
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 338 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 484
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPAC 114
>AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein.
Length = 396
Score = 117 bits (282), Expect = 5e-26
Identities = 56/109 (51%), Positives = 76/109 (69%), Gaps = 1/109 (0%)
Frame = +3
Query: 492 HNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 671
H+++ +S TY G F+IQYG+GSLSG + D V+V GL V Q F E+V+EPG F
Sbjct: 117 HSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTF 176
Query: 672 VAAKFDGILGMAFSTIAVDHVXPVFDNMVAQGLVQ-PVFSFYLNRDPGG 815
V A+FDGILG+ + ++AV V PVFDNM+AQ LV P+FS Y++ +P G
Sbjct: 177 VDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEG 225
Score = 77.4 bits (182), Expect = 7e-14
Identities = 46/109 (42%), Positives = 63/109 (57%), Gaps = 10/109 (9%)
Frame = +2
Query: 188 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 337
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 338 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 484
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPAC 114
>AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternative
protein.
Length = 363
Score = 117 bits (282), Expect = 5e-26
Identities = 56/109 (51%), Positives = 76/109 (69%), Gaps = 1/109 (0%)
Frame = +3
Query: 492 HNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 671
H+++ +S TY G F+IQYG+GSLSG + D V+V GL V Q F E+V+EPG F
Sbjct: 117 HSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTF 176
Query: 672 VAAKFDGILGMAFSTIAVDHVXPVFDNMVAQGLVQ-PVFSFYLNRDPGG 815
V A+FDGILG+ + ++AV V PVFDNM+AQ LV P+FS Y++ +P G
Sbjct: 177 VDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEG 225
Score = 77.4 bits (182), Expect = 7e-14
Identities = 46/109 (42%), Positives = 63/109 (57%), Gaps = 10/109 (9%)
Frame = +2
Query: 188 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 337
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 338 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 484
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPAC 114
>X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mRNA
fragment for renin (aa 105-401). ).
Length = 300
Score = 107 bits (258), Expect = 4e-23
Identities = 50/106 (47%), Positives = 71/106 (66%), Gaps = 1/106 (0%)
Frame = +3
Query: 492 HNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 671
H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F
Sbjct: 20 HKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVT-QMFGEVTEMPALPF 78
Query: 672 VAAKFDGILGMAFSTIAVDHVXPVFDNMVAQG-LVQPVFSFYLNRD 806
+ A+FDG++GM F A+ V P+FDN+++QG L + VFSFY NRD
Sbjct: 79 MLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRD 124
>M10152-1|AAD03461.1| 406|Homo sapiens renin protein.
Length = 406
Score = 107 bits (258), Expect = 4e-23
Identities = 50/106 (47%), Positives = 71/106 (66%), Gaps = 1/106 (0%)
Frame = +3
Query: 492 HNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 671
H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F
Sbjct: 127 HKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVT-QMFGEVTEMPALPF 185
Query: 672 VAAKFDGILGMAFSTIAVDHVXPVFDNMVAQG-LVQPVFSFYLNRD 806
+ A+FDG++GM F A+ V P+FDN+++QG L + VFSFY NRD
Sbjct: 186 MLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRD 231
Score = 81.0 bits (191), Expect = 5e-15
Identities = 34/47 (72%), Positives = 38/47 (80%)
Frame = +2
Query: 344 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 484
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTAC 124
>L00073-1|AAA60363.1| 406|Homo sapiens renin protein.
Length = 406
Score = 107 bits (258), Expect = 4e-23
Identities = 50/106 (47%), Positives = 71/106 (66%), Gaps = 1/106 (0%)
Frame = +3
Query: 492 HNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 671
H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F
Sbjct: 127 HKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVT-QMFGEVTEMPALPF 185
Query: 672 VAAKFDGILGMAFSTIAVDHVXPVFDNMVAQG-LVQPVFSFYLNRD 806
+ A+FDG++GM F A+ V P+FDN+++QG L + VFSFY NRD
Sbjct: 186 MLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRD 231
Score = 81.0 bits (191), Expect = 5e-15
Identities = 34/47 (72%), Positives = 38/47 (80%)
Frame = +2
Query: 344 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 484
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTAC 124
>CR536498-1|CAG38737.1| 406|Homo sapiens REN protein.
Length = 406
Score = 107 bits (258), Expect = 4e-23
Identities = 50/106 (47%), Positives = 71/106 (66%), Gaps = 1/106 (0%)
Frame = +3
Query: 492 HNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 671
H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F
Sbjct: 127 HKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVT-QMFGEVTEMPALPF 185
Query: 672 VAAKFDGILGMAFSTIAVDHVXPVFDNMVAQG-LVQPVFSFYLNRD 806
+ A+FDG++GM F A+ V P+FDN+++QG L + VFSFY NRD
Sbjct: 186 MLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRD 231
Score = 81.0 bits (191), Expect = 5e-15
Identities = 34/47 (72%), Positives = 38/47 (80%)
Frame = +2
Query: 344 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 484
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTAC 124
>BC047752-1|AAH47752.1| 406|Homo sapiens renin protein.
Length = 406
Score = 107 bits (258), Expect = 4e-23
Identities = 50/106 (47%), Positives = 71/106 (66%), Gaps = 1/106 (0%)
Frame = +3
Query: 492 HNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 671
H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F
Sbjct: 127 HKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVT-QMFGEVTEMPALPF 185
Query: 672 VAAKFDGILGMAFSTIAVDHVXPVFDNMVAQG-LVQPVFSFYLNRD 806
+ A+FDG++GM F A+ V P+FDN+++QG L + VFSFY NRD
Sbjct: 186 MLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRD 231
Score = 81.0 bits (191), Expect = 5e-15
Identities = 34/47 (72%), Positives = 38/47 (80%)
Frame = +2
Query: 344 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 484
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTAC 124
>BC033474-1|AAH33474.1| 406|Homo sapiens renin protein.
Length = 406
Score = 107 bits (258), Expect = 4e-23
Identities = 50/106 (47%), Positives = 71/106 (66%), Gaps = 1/106 (0%)
Frame = +3
Query: 492 HNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 671
H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F
Sbjct: 127 HKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVT-QMFGEVTEMPALPF 185
Query: 672 VAAKFDGILGMAFSTIAVDHVXPVFDNMVAQG-LVQPVFSFYLNRD 806
+ A+FDG++GM F A+ V P+FDN+++QG L + VFSFY NRD
Sbjct: 186 MLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRD 231
Score = 81.0 bits (191), Expect = 5e-15
Identities = 34/47 (72%), Positives = 38/47 (80%)
Frame = +2
Query: 344 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 484
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTAC 124
>AL592146-1|CAI16594.1| 406|Homo sapiens renin protein.
Length = 406
Score = 107 bits (258), Expect = 4e-23
Identities = 50/106 (47%), Positives = 71/106 (66%), Gaps = 1/106 (0%)
Frame = +3
Query: 492 HNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 671
H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F
Sbjct: 127 HKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVT-QMFGEVTEMPALPF 185
Query: 672 VAAKFDGILGMAFSTIAVDHVXPVFDNMVAQG-LVQPVFSFYLNRD 806
+ A+FDG++GM F A+ V P+FDN+++QG L + VFSFY NRD
Sbjct: 186 MLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRD 231
Score = 81.0 bits (191), Expect = 5e-15
Identities = 34/47 (72%), Positives = 38/47 (80%)
Frame = +2
Query: 344 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 484
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTAC 124
>AL592114-1|CAH71224.1| 406|Homo sapiens renin protein.
Length = 406
Score = 107 bits (258), Expect = 4e-23
Identities = 50/106 (47%), Positives = 71/106 (66%), Gaps = 1/106 (0%)
Frame = +3
Query: 492 HNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 671
H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F
Sbjct: 127 HKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVT-QMFGEVTEMPALPF 185
Query: 672 VAAKFDGILGMAFSTIAVDHVXPVFDNMVAQG-LVQPVFSFYLNRD 806
+ A+FDG++GM F A+ V P+FDN+++QG L + VFSFY NRD
Sbjct: 186 MLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRD 231
Score = 81.0 bits (191), Expect = 5e-15
Identities = 34/47 (72%), Positives = 38/47 (80%)
Frame = +2
Query: 344 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 484
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTAC 124
>M26901-1|AAA60364.1| 403|Homo sapiens renin protein.
Length = 403
Score = 105 bits (253), Expect = 2e-22
Identities = 49/106 (46%), Positives = 71/106 (66%), Gaps = 1/106 (0%)
Frame = +3
Query: 492 HNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 671
H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F
Sbjct: 127 HKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVT-QMFGEVTEMPALPF 185
Query: 672 VAAKFDGILGMAFSTIAVDHVXPVFDNMVAQG-LVQPVFSFYLNRD 806
+ A+FDG++GM F A+ V P+FDN+++QG L + VFSFY NR+
Sbjct: 186 MLAQFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRN 231
Score = 81.0 bits (191), Expect = 5e-15
Identities = 34/47 (72%), Positives = 38/47 (80%)
Frame = +2
Query: 344 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 484
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTAC 124
>BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein.
Length = 464
Score = 105 bits (253), Expect = 2e-22
Identities = 49/107 (45%), Positives = 72/107 (67%), Gaps = 1/107 (0%)
Frame = +3
Query: 492 HNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 671
H++++ S ++ +GT+FAIQYG+G + G LS D +T+GG+K F EA+ E L F
Sbjct: 115 HHRFNPNASSSFKPSGTKFAIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWESSLVF 174
Query: 672 VAAKFDGILGMAFSTIAVDHVXPVFDNMVAQGLV-QPVFSFYLNRDP 809
++ DGILG+ F ++V+ V P D +V QGL+ +PVFSFY NRDP
Sbjct: 175 TVSRPDGILGLGFPILSVEGVRPPLDVLVEQGLLDKPVFSFYFNRDP 221
Score = 89.4 bits (212), Expect = 2e-17
Identities = 43/92 (46%), Positives = 59/92 (64%), Gaps = 5/92 (5%)
Frame = +2
Query: 227 LYRVPLHRMKTARTHFHEV---GTELELLRLKYDVTGPSPE--PLSNYLDAQYYGVISIG 391
L R+PL ++ R + + G EL +L G P PLS +LDAQY+G I +G
Sbjct: 22 LIRIPLRQVHPGRRTLNLLRGWGKPAELPKLGAPSPGDKPASVPLSKFLDAQYFGEIGLG 81
Query: 392 TPPQSFKVVFDTGSSNLWVPSKKCHYTNIACF 487
TPPQ+F V FDTGSSNLWVPS++CH+ ++ C+
Sbjct: 82 TPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCW 113
>AY436324-1|AAR03502.1| 403|Homo sapiens renin protein.
Length = 403
Score = 105 bits (253), Expect = 2e-22
Identities = 49/106 (46%), Positives = 71/106 (66%), Gaps = 1/106 (0%)
Frame = +3
Query: 492 HNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 671
H +D+ S +Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F
Sbjct: 127 HKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVT-QMFGEVTEMPALPF 185
Query: 672 VAAKFDGILGMAFSTIAVDHVXPVFDNMVAQG-LVQPVFSFYLNRD 806
+ A+FDG++GM F A+ V P+FDN+++QG L + VFSFY NR+
Sbjct: 186 MLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRN 231
Score = 81.0 bits (191), Expect = 5e-15
Identities = 34/47 (72%), Positives = 38/47 (80%)
Frame = +2
Query: 344 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 484
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTAC 124
>AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3
protein.
Length = 450
Score = 105 bits (253), Expect = 2e-22
Identities = 49/107 (45%), Positives = 72/107 (67%), Gaps = 1/107 (0%)
Frame = +3
Query: 492 HNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 671
H++++ S ++ +GT+FAIQYG+G + G LS D +T+GG+K F EA+ E L F
Sbjct: 119 HHRFNPNASSSFKPSGTKFAIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWESSLVF 178
Query: 672 VAAKFDGILGMAFSTIAVDHVXPVFDNMVAQGLV-QPVFSFYLNRDP 809
++ DGILG+ F ++V+ V P D +V QGL+ +PVFSFY NRDP
Sbjct: 179 TVSRPDGILGLGFPILSVEGVRPPLDVLVEQGLLDKPVFSFYFNRDP 225
Score = 89.4 bits (212), Expect = 2e-17
Identities = 43/92 (46%), Positives = 59/92 (64%), Gaps = 5/92 (5%)
Frame = +2
Query: 227 LYRVPLHRMKTARTHFHEV---GTELELLRLKYDVTGPSPE--PLSNYLDAQYYGVISIG 391
L R+PL ++ R + + G EL +L G P PLS +LDAQY+G I +G
Sbjct: 26 LIRIPLRQVHPGRRTLNLLRGWGKPAELPKLGAPSPGDKPASVPLSKFLDAQYFGEIGLG 85
Query: 392 TPPQSFKVVFDTGSSNLWVPSKKCHYTNIACF 487
TPPQ+F V FDTGSSNLWVPS++CH+ ++ C+
Sbjct: 86 TPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCW 117
>U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein.
Length = 388
Score = 101 bits (242), Expect = 4e-21
Identities = 47/108 (43%), Positives = 68/108 (62%), Gaps = 1/108 (0%)
Frame = +3
Query: 492 HNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 671
H++++ +S TY NG F++QYGSGSL+GF D +TV ++V Q F + +EPG F
Sbjct: 112 HSRFNPSESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNF 171
Query: 672 VAAKFDGILGMAFSTIAVDHVXPVFDNMVAQG-LVQPVFSFYLNRDPG 812
V A+FDGI+G+A+ ++VD MV +G L PVFS YL+ G
Sbjct: 172 VYAQFDGIMGLAYPALSVDEATTAMQGMVQEGALTSPVFSVYLSNQQG 219
Score = 75.8 bits (178), Expect = 2e-13
Identities = 44/89 (49%), Positives = 55/89 (61%), Gaps = 9/89 (10%)
Frame = +2
Query: 224 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 376
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 377 VISIGTPPQSFKVVFDTGSSNLWVPSKKC 463
ISIGTPPQ+F V+FDTGSSNLWVPS C
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYC 104
>M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein.
Length = 388
Score = 101 bits (242), Expect = 4e-21
Identities = 47/108 (43%), Positives = 68/108 (62%), Gaps = 1/108 (0%)
Frame = +3
Query: 492 HNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 671
H++++ +S TY NG F++QYGSGSL+GF D +TV ++V Q F + +EPG F
Sbjct: 112 HSRFNPSESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNF 171
Query: 672 VAAKFDGILGMAFSTIAVDHVXPVFDNMVAQG-LVQPVFSFYLNRDPG 812
V A+FDGI+G+A+ ++VD MV +G L PVFS YL+ G
Sbjct: 172 VYAQFDGIMGLAYPALSVDEATTAMQGMVQEGALTSPVFSVYLSNQQG 219
Score = 75.8 bits (178), Expect = 2e-13
Identities = 44/89 (49%), Positives = 55/89 (61%), Gaps = 9/89 (10%)
Frame = +2
Query: 224 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 376
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 377 VISIGTPPQSFKVVFDTGSSNLWVPSKKC 463
ISIGTPPQ+F V+FDTGSSNLWVPS C
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYC 104
>M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein.
Length = 385
Score = 101 bits (242), Expect = 4e-21
Identities = 47/108 (43%), Positives = 68/108 (62%), Gaps = 1/108 (0%)
Frame = +3
Query: 492 HNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 671
H++++ +S TY NG F++QYGSGSL+GF D +TV ++V Q F + +EPG F
Sbjct: 109 HSRFNPSESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNF 168
Query: 672 VAAKFDGILGMAFSTIAVDHVXPVFDNMVAQG-LVQPVFSFYLNRDPG 812
V A+FDGI+G+A+ ++VD MV +G L PVFS YL+ G
Sbjct: 169 VYAQFDGIMGLAYPALSVDEATTAMQGMVQEGALTSPVFSVYLSNQQG 216
Score = 75.8 bits (178), Expect = 2e-13
Identities = 44/89 (49%), Positives = 55/89 (61%), Gaps = 9/89 (10%)
Frame = +2
Query: 224 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 376
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 14 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 72
Query: 377 VISIGTPPQSFKVVFDTGSSNLWVPSKKC 463
ISIGTPPQ+F V+FDTGSSNLWVPS C
Sbjct: 73 EISIGTPPQNFLVLFDTGSSNLWVPSVYC 101
>J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein.
Length = 388
Score = 101 bits (242), Expect = 4e-21
Identities = 47/108 (43%), Positives = 68/108 (62%), Gaps = 1/108 (0%)
Frame = +3
Query: 492 HNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 671
H++++ +S TY NG F++QYGSGSL+GF D +TV ++V Q F + +EPG F
Sbjct: 112 HSRFNPSESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNF 171
Query: 672 VAAKFDGILGMAFSTIAVDHVXPVFDNMVAQG-LVQPVFSFYLNRDPG 812
V A+FDGI+G+A+ ++VD MV +G L PVFS YL+ G
Sbjct: 172 VYAQFDGIMGLAYPALSVDEATTAMQGMVQEGALTSPVFSVYLSNQQG 219
Score = 75.8 bits (178), Expect = 2e-13
Identities = 44/89 (49%), Positives = 55/89 (61%), Gaps = 9/89 (10%)
Frame = +2
Query: 224 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 376
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 377 VISIGTPPQSFKVVFDTGSSNLWVPSKKC 463
ISIGTPPQ+F V+FDTGSSNLWVPS C
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYC 104
>BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 101 bits (242), Expect = 4e-21
Identities = 47/108 (43%), Positives = 68/108 (62%), Gaps = 1/108 (0%)
Frame = +3
Query: 492 HNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 671
H++++ +S TY NG F++QYGSGSL+GF D +TV ++V Q F + +EPG F
Sbjct: 112 HSRFNPSESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNF 171
Query: 672 VAAKFDGILGMAFSTIAVDHVXPVFDNMVAQG-LVQPVFSFYLNRDPG 812
V A+FDGI+G+A+ ++VD MV +G L PVFS YL+ G
Sbjct: 172 VYAQFDGIMGLAYPALSVDEATTAMQGMVQEGALTSPVFSVYLSNQQG 219
Score = 75.8 bits (178), Expect = 2e-13
Identities = 44/89 (49%), Positives = 55/89 (61%), Gaps = 9/89 (10%)
Frame = +2
Query: 224 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 376
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 377 VISIGTPPQSFKVVFDTGSSNLWVPSKKC 463
ISIGTPPQ+F V+FDTGSSNLWVPS C
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYC 104
>AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 101 bits (242), Expect = 4e-21
Identities = 47/108 (43%), Positives = 68/108 (62%), Gaps = 1/108 (0%)
Frame = +3
Query: 492 HNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 671
H++++ +S TY NG F++QYGSGSL+GF D +TV ++V Q F + +EPG F
Sbjct: 112 HSRFNPSESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNF 171
Query: 672 VAAKFDGILGMAFSTIAVDHVXPVFDNMVAQG-LVQPVFSFYLNRDPG 812
V A+FDGI+G+A+ ++VD MV +G L PVFS YL+ G
Sbjct: 172 VYAQFDGIMGLAYPALSVDEATTAMQGMVQEGALTSPVFSVYLSNQQG 219
Score = 75.8 bits (178), Expect = 2e-13
Identities = 44/89 (49%), Positives = 55/89 (61%), Gaps = 9/89 (10%)
Frame = +2
Query: 224 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 376
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 377 VISIGTPPQSFKVVFDTGSSNLWVPSKKC 463
ISIGTPPQ+F V+FDTGSSNLWVPS C
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYC 104
>M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein.
Length = 388
Score = 91.5 bits (217), Expect = 4e-18
Identities = 46/106 (43%), Positives = 64/106 (60%), Gaps = 1/106 (0%)
Frame = +3
Query: 492 HNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 671
HN+++ S TY + +I YG+GS++G L D V VGG+ Q F + +EPG
Sbjct: 115 HNRFNPEDSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFL 174
Query: 672 VAAKFDGILGMAFSTIAVDHVXPVFDNMVAQGLV-QPVFSFYLNRD 806
A FDGILG+A+ +I+ PVFDN+ QGLV Q +FS YL+ D
Sbjct: 175 YYAPFDGILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSAD 220
Score = 82.6 bits (195), Expect = 2e-15
Identities = 49/111 (44%), Positives = 63/111 (56%), Gaps = 12/111 (10%)
Frame = +2
Query: 188 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 337
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSFRRTLSERGLLKDFLKKHNLNPARKYFPQWKAPTLV 63
Query: 338 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 484
+PL NYLD +Y+G I IGTP Q F V+FDTGSSNLWVPS C +++AC
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVLFDTGSSNLWVPSVYC--SSLAC 112
>J00287-1|AAA98529.1| 388|Homo sapiens PEP protein.
Length = 388
Score = 91.5 bits (217), Expect = 4e-18
Identities = 46/106 (43%), Positives = 64/106 (60%), Gaps = 1/106 (0%)
Frame = +3
Query: 492 HNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 671
HN+++ S TY + +I YG+GS++G L D V VGG+ Q F + +EPG
Sbjct: 115 HNRFNPEDSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFL 174
Query: 672 VAAKFDGILGMAFSTIAVDHVXPVFDNMVAQGLV-QPVFSFYLNRD 806
A FDGILG+A+ +I+ PVFDN+ QGLV Q +FS YL+ D
Sbjct: 175 YYAPFDGILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSAD 220
Score = 84.2 bits (199), Expect = 6e-16
Identities = 50/111 (45%), Positives = 63/111 (56%), Gaps = 12/111 (10%)
Frame = +2
Query: 188 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 337
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLV 63
Query: 338 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 484
+PL NYLD +Y+G I IGTP Q F VVFDTGSSNLWVPS C +++AC
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYC--SSLAC 112
>BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I
(pepsinogen A) protein.
Length = 388
Score = 91.5 bits (217), Expect = 4e-18
Identities = 46/106 (43%), Positives = 64/106 (60%), Gaps = 1/106 (0%)
Frame = +3
Query: 492 HNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAF 671
HN+++ S TY + +I YG+GS++G L D V VGG+ Q F + +EPG
Sbjct: 115 HNRFNPEDSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFL 174
Query: 672 VAAKFDGILGMAFSTIAVDHVXPVFDNMVAQGLV-QPVFSFYLNRD 806
A FDGILG+A+ +I+ PVFDN+ QGLV Q +FS YL+ D
Sbjct: 175 YYAPFDGILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSAD 220
Score = 84.2 bits (199), Expect = 6e-16
Identities = 50/111 (45%), Positives = 63/111 (56%), Gaps = 12/111 (10%)
Frame = +2
Query: 188 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 337
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLV 63
Query: 338 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 484
+PL NYLD +Y+G I IGTP Q F VVFDTGSSNLWVPS C +++AC
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYC--SSLAC 112
>BC042578-1|AAH42578.1| 104|Homo sapiens PGC protein protein.
Length = 104
Score = 60.1 bits (139), Expect = 1e-08
Identities = 38/82 (46%), Positives = 49/82 (59%), Gaps = 9/82 (10%)
Frame = +2
Query: 224 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 376
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 377 VISIGTPPQSFKVVFDTGSSNL 442
ISIGTPPQ+F V+FDTGSS L
Sbjct: 76 EISIGTPPQNFLVLFDTGSSPL 97
>AL365205-2|CAI95135.1| 140|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 140
Score = 59.3 bits (137), Expect = 2e-08
Identities = 29/70 (41%), Positives = 41/70 (58%), Gaps = 1/70 (1%)
Frame = +3
Query: 606 VGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVXPVFDNMVAQG-LVQPV 782
V ++V Q F + +EPG FV A+FDGI+G+A+ ++VD MV +G L PV
Sbjct: 71 VQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEATTAMQGMVQEGALTSPV 130
Query: 783 FSFYLNRDPG 812
FS YL+ G
Sbjct: 131 FSVYLSNQQG 140
>AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens
cDNA PSEC0239 fis, clone OVARC1000363, highly similar to
Homo sapiens aspartyl protease mRNA. ).
Length = 423
Score = 52.4 bits (120), Expect = 2e-06
Identities = 35/116 (30%), Positives = 60/116 (51%), Gaps = 4/116 (3%)
Frame = +3
Query: 462 ATTPTSLVLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV-GGLKVRRQTF 638
A TP S + + +D+ +S TY + G ++Y GS +GF+ D VT+ G
Sbjct: 24 AGTPHSYIDTY--FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVN 81
Query: 639 AEAVSEPGLAFV-AAKFDGILGMAFSTIA--VDHVXPVFDNMVAQGLVQPVFSFYL 797
+ E G F+ +++GILG+A++T+A + FD++V Q + VFS +
Sbjct: 82 IATIFESGNFFLPGIQWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQM 137
Score = 32.3 bits (70), Expect = 2.4
Identities = 13/21 (61%), Positives = 16/21 (76%)
Frame = +2
Query: 386 IGTPPQSFKVVFDTGSSNLWV 448
IGTPPQ +++ DTGSSN V
Sbjct: 3 IGTPPQKLQILVDTGSSNFAV 23
>BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving
enzyme 2 protein.
Length = 518
Score = 50.8 bits (116), Expect = 6e-06
Identities = 35/116 (30%), Positives = 59/116 (50%), Gaps = 4/116 (3%)
Frame = +3
Query: 462 ATTPTSLVLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV-GGLKVRRQTF 638
A TP S + + +D+ +S TY + G ++Y GS +GF+ D VT+ G
Sbjct: 119 AGTPHSYIDTY--FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVN 176
Query: 639 AEAVSEPGLAFV-AAKFDGILGMAFSTIA--VDHVXPVFDNMVAQGLVQPVFSFYL 797
+ E F+ K++GILG+A++T+A + FD++V Q + VFS +
Sbjct: 177 IATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQM 232
Score = 35.1 bits (77), Expect = 0.34
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +2
Query: 368 YYGVISIGTPPQSFKVVFDTGSSNLWV 448
YY + IGTPPQ +++ DTGSSN V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein.
Length = 518
Score = 50.8 bits (116), Expect = 6e-06
Identities = 35/116 (30%), Positives = 59/116 (50%), Gaps = 4/116 (3%)
Frame = +3
Query: 462 ATTPTSLVLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV-GGLKVRRQTF 638
A TP S + + +D+ +S TY + G ++Y GS +GF+ D VT+ G
Sbjct: 119 AGTPHSYIDTY--FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVN 176
Query: 639 AEAVSEPGLAFV-AAKFDGILGMAFSTIA--VDHVXPVFDNMVAQGLVQPVFSFYL 797
+ E F+ K++GILG+A++T+A + FD++V Q + VFS +
Sbjct: 177 IATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQM 232
Score = 35.1 bits (77), Expect = 0.34
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +2
Query: 368 YYGVISIGTPPQSFKVVFDTGSSNLWV 448
YY + IGTPPQ +++ DTGSSN V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AL163285-1|CAB90554.1| 415|Homo sapiens beta-site APP-cleaving
enzyme 2, EC 3.4.23. protein.
Length = 415
Score = 50.8 bits (116), Expect = 6e-06
Identities = 35/116 (30%), Positives = 59/116 (50%), Gaps = 4/116 (3%)
Frame = +3
Query: 462 ATTPTSLVLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV-GGLKVRRQTF 638
A TP S + + +D+ +S TY + G ++Y GS +GF+ D VT+ G
Sbjct: 16 AGTPHSYIDTY--FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVN 73
Query: 639 AEAVSEPGLAFV-AAKFDGILGMAFSTIA--VDHVXPVFDNMVAQGLVQPVFSFYL 797
+ E F+ K++GILG+A++T+A + FD++V Q + VFS +
Sbjct: 74 IATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQM 129
>AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein.
Length = 439
Score = 50.8 bits (116), Expect = 6e-06
Identities = 35/116 (30%), Positives = 59/116 (50%), Gaps = 4/116 (3%)
Frame = +3
Query: 462 ATTPTSLVLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV-GGLKVRRQTF 638
A TP S + + +D+ +S TY + G ++Y GS +GF+ D VT+ G
Sbjct: 40 AGTPHSYIDTY--FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVN 97
Query: 639 AEAVSEPGLAFV-AAKFDGILGMAFSTIA--VDHVXPVFDNMVAQGLVQPVFSFYL 797
+ E F+ K++GILG+A++T+A + FD++V Q + VFS +
Sbjct: 98 IATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQM 153
Score = 35.1 bits (77), Expect = 0.34
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +2
Query: 368 YYGVISIGTPPQSFKVVFDTGSSNLWV 448
YY + IGTPPQ +++ DTGSSN V
Sbjct: 13 YYLEMLIGTPPQKLQILVDTGSSNFAV 39
>AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic
proteinase Asp 1 protein.
Length = 518
Score = 50.8 bits (116), Expect = 6e-06
Identities = 35/116 (30%), Positives = 59/116 (50%), Gaps = 4/116 (3%)
Frame = +3
Query: 462 ATTPTSLVLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV-GGLKVRRQTF 638
A TP S + + +D+ +S TY + G ++Y GS +GF+ D VT+ G
Sbjct: 119 AGTPHSYIDTY--FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVN 176
Query: 639 AEAVSEPGLAFV-AAKFDGILGMAFSTIA--VDHVXPVFDNMVAQGLVQPVFSFYL 797
+ E F+ K++GILG+A++T+A + FD++V Q + VFS +
Sbjct: 177 IATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQM 232
Score = 35.1 bits (77), Expect = 0.34
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +2
Query: 368 YYGVISIGTPPQSFKVVFDTGSSNLWV 448
YY + IGTPPQ +++ DTGSSN V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1
protein.
Length = 518
Score = 50.8 bits (116), Expect = 6e-06
Identities = 35/116 (30%), Positives = 59/116 (50%), Gaps = 4/116 (3%)
Frame = +3
Query: 462 ATTPTSLVLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV-GGLKVRRQTF 638
A TP S + + +D+ +S TY + G ++Y GS +GF+ D VT+ G
Sbjct: 119 AGTPHSYIDTY--FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVN 176
Query: 639 AEAVSEPGLAFV-AAKFDGILGMAFSTIA--VDHVXPVFDNMVAQGLVQPVFSFYL 797
+ E F+ K++GILG+A++T+A + FD++V Q + VFS +
Sbjct: 177 IATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQM 232
Score = 35.1 bits (77), Expect = 0.34
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +2
Query: 368 YYGVISIGTPPQSFKVVFDTGSSNLWV 448
YY + IGTPPQ +++ DTGSSN V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein.
Length = 518
Score = 50.8 bits (116), Expect = 6e-06
Identities = 35/116 (30%), Positives = 59/116 (50%), Gaps = 4/116 (3%)
Frame = +3
Query: 462 ATTPTSLVLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV-GGLKVRRQTF 638
A TP S + + +D+ +S TY + G ++Y GS +GF+ D VT+ G
Sbjct: 119 AGTPHSYIDTY--FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVN 176
Query: 639 AEAVSEPGLAFV-AAKFDGILGMAFSTIA--VDHVXPVFDNMVAQGLVQPVFSFYL 797
+ E F+ K++GILG+A++T+A + FD++V Q + VFS +
Sbjct: 177 IATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQM 232
Score = 35.1 bits (77), Expect = 0.34
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +2
Query: 368 YYGVISIGTPPQSFKVVFDTGSSNLWV 448
YY + IGTPPQ +++ DTGSSN V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein.
Length = 396
Score = 50.8 bits (116), Expect = 6e-06
Identities = 35/116 (30%), Positives = 59/116 (50%), Gaps = 4/116 (3%)
Frame = +3
Query: 462 ATTPTSLVLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV-GGLKVRRQTF 638
A TP S + + +D+ +S TY + G ++Y GS +GF+ D VT+ G
Sbjct: 119 AGTPHSYIDTY--FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVN 176
Query: 639 AEAVSEPGLAFV-AAKFDGILGMAFSTIA--VDHVXPVFDNMVAQGLVQPVFSFYL 797
+ E F+ K++GILG+A++T+A + FD++V Q + VFS +
Sbjct: 177 IATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQM 232
Score = 35.1 bits (77), Expect = 0.34
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +2
Query: 368 YYGVISIGTPPQSFKVVFDTGSSNLWV 448
YY + IGTPPQ +++ DTGSSN V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein.
Length = 468
Score = 50.8 bits (116), Expect = 6e-06
Identities = 35/116 (30%), Positives = 59/116 (50%), Gaps = 4/116 (3%)
Frame = +3
Query: 462 ATTPTSLVLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV-GGLKVRRQTF 638
A TP S + + +D+ +S TY + G ++Y GS +GF+ D VT+ G
Sbjct: 119 AGTPHSYIDTY--FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVN 176
Query: 639 AEAVSEPGLAFV-AAKFDGILGMAFSTIA--VDHVXPVFDNMVAQGLVQPVFSFYL 797
+ E F+ K++GILG+A++T+A + FD++V Q + VFS +
Sbjct: 177 IATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQM 232
Score = 35.1 bits (77), Expect = 0.34
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +2
Query: 368 YYGVISIGTPPQSFKVVFDTGSSNLWV 448
YY + IGTPPQ +++ DTGSSN V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 50.8 bits (116), Expect = 6e-06
Identities = 35/116 (30%), Positives = 59/116 (50%), Gaps = 4/116 (3%)
Frame = +3
Query: 462 ATTPTSLVLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV-GGLKVRRQTF 638
A TP S + + +D+ +S TY + G ++Y GS +GF+ D VT+ G
Sbjct: 119 AGTPHSYIDTY--FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVN 176
Query: 639 AEAVSEPGLAFV-AAKFDGILGMAFSTIA--VDHVXPVFDNMVAQGLVQPVFSFYL 797
+ E F+ K++GILG+A++T+A + FD++V Q + VFS +
Sbjct: 177 IATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQM 232
Score = 35.1 bits (77), Expect = 0.34
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +2
Query: 368 YYGVISIGTPPQSFKVVFDTGSSNLWV 448
YY + IGTPPQ +++ DTGSSN V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease
protein.
Length = 518
Score = 50.8 bits (116), Expect = 6e-06
Identities = 35/116 (30%), Positives = 59/116 (50%), Gaps = 4/116 (3%)
Frame = +3
Query: 462 ATTPTSLVLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV-GGLKVRRQTF 638
A TP S + + +D+ +S TY + G ++Y GS +GF+ D VT+ G
Sbjct: 119 AGTPHSYIDTY--FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVN 176
Query: 639 AEAVSEPGLAFV-AAKFDGILGMAFSTIA--VDHVXPVFDNMVAQGLVQPVFSFYL 797
+ E F+ K++GILG+A++T+A + FD++V Q + VFS +
Sbjct: 177 IATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQM 232
Score = 35.1 bits (77), Expect = 0.34
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +2
Query: 368 YYGVISIGTPPQSFKVVFDTGSSNLWV 448
YY + IGTPPQ +++ DTGSSN V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 50.8 bits (116), Expect = 6e-06
Identities = 35/116 (30%), Positives = 59/116 (50%), Gaps = 4/116 (3%)
Frame = +3
Query: 462 ATTPTSLVLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTV-GGLKVRRQTF 638
A TP S + + +D+ +S TY + G ++Y GS +GF+ D VT+ G
Sbjct: 119 AGTPHSYIDTY--FDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVN 176
Query: 639 AEAVSEPGLAFV-AAKFDGILGMAFSTIA--VDHVXPVFDNMVAQGLVQPVFSFYL 797
+ E F+ K++GILG+A++T+A + FD++V Q + VFS +
Sbjct: 177 IATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQM 232
Score = 35.1 bits (77), Expect = 0.34
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +2
Query: 368 YYGVISIGTPPQSFKVVFDTGSSNLWV 448
YY + IGTPPQ +++ DTGSSN V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 47.6 bits (108), Expect = 6e-05
Identities = 35/107 (32%), Positives = 53/107 (49%), Gaps = 4/107 (3%)
Frame = +3
Query: 489 LHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVG-GLKVRRQTFAEAVSEPGL 665
LH Y + S TY + Y G G L TD V++ G V + A++E
Sbjct: 109 LHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDK 168
Query: 666 AFV-AAKFDGILGMAFSTIA--VDHVXPVFDNMVAQGLVQPVFSFYL 797
F+ + ++GILG+A++ IA D + P FD++V Q V +FS L
Sbjct: 169 FFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQL 215
Score = 34.7 bits (76), Expect = 0.46
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +2
Query: 368 YYGVISIGTPPQSFKVVFDTGSSNLWV 448
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 47.6 bits (108), Expect = 6e-05
Identities = 35/107 (32%), Positives = 53/107 (49%), Gaps = 4/107 (3%)
Frame = +3
Query: 489 LHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVG-GLKVRRQTFAEAVSEPGL 665
LH Y + S TY + Y G G L TD V++ G V + A++E
Sbjct: 109 LHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDK 168
Query: 666 AFV-AAKFDGILGMAFSTIA--VDHVXPVFDNMVAQGLVQPVFSFYL 797
F+ + ++GILG+A++ IA D + P FD++V Q V +FS L
Sbjct: 169 FFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQL 215
Score = 34.7 bits (76), Expect = 0.46
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +2
Query: 368 YYGVISIGTPPQSFKVVFDTGSSNLWV 448
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic
proteinase Asp 2 protein.
Length = 501
Score = 47.6 bits (108), Expect = 6e-05
Identities = 35/107 (32%), Positives = 53/107 (49%), Gaps = 4/107 (3%)
Frame = +3
Query: 489 LHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVG-GLKVRRQTFAEAVSEPGL 665
LH Y + S TY + Y G G L TD V++ G V + A++E
Sbjct: 109 LHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDK 168
Query: 666 AFV-AAKFDGILGMAFSTIA--VDHVXPVFDNMVAQGLVQPVFSFYL 797
F+ + ++GILG+A++ IA D + P FD++V Q V +FS L
Sbjct: 169 FFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQL 215
Score = 34.7 bits (76), Expect = 0.46
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +2
Query: 368 YYGVISIGTPPQSFKVVFDTGSSNLWV 448
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase
protein.
Length = 501
Score = 47.6 bits (108), Expect = 6e-05
Identities = 35/107 (32%), Positives = 53/107 (49%), Gaps = 4/107 (3%)
Frame = +3
Query: 489 LHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVG-GLKVRRQTFAEAVSEPGL 665
LH Y + S TY + Y G G L TD V++ G V + A++E
Sbjct: 109 LHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDK 168
Query: 666 AFV-AAKFDGILGMAFSTIA--VDHVXPVFDNMVAQGLVQPVFSFYL 797
F+ + ++GILG+A++ IA D + P FD++V Q V +FS L
Sbjct: 169 FFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQL 215
Score = 34.7 bits (76), Expect = 0.46
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +2
Query: 368 YYGVISIGTPPQSFKVVFDTGSSNLWV 448
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2
protein.
Length = 501
Score = 47.6 bits (108), Expect = 6e-05
Identities = 35/107 (32%), Positives = 53/107 (49%), Gaps = 4/107 (3%)
Frame = +3
Query: 489 LHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVG-GLKVRRQTFAEAVSEPGL 665
LH Y + S TY + Y G G L TD V++ G V + A++E
Sbjct: 109 LHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDK 168
Query: 666 AFV-AAKFDGILGMAFSTIA--VDHVXPVFDNMVAQGLVQPVFSFYL 797
F+ + ++GILG+A++ IA D + P FD++V Q V +FS L
Sbjct: 169 FFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQL 215
Score = 34.7 bits (76), Expect = 0.46
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +2
Query: 368 YYGVISIGTPPQSFKVVFDTGSSNLWV 448
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein.
Length = 488
Score = 47.6 bits (108), Expect = 6e-05
Identities = 35/107 (32%), Positives = 53/107 (49%), Gaps = 4/107 (3%)
Frame = +3
Query: 489 LHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVG-GLKVRRQTFAEAVSEPGL 665
LH Y + S TY + Y G G L TD V++ G V + A++E
Sbjct: 96 LHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDK 155
Query: 666 AFV-AAKFDGILGMAFSTIA--VDHVXPVFDNMVAQGLVQPVFSFYL 797
F+ + ++GILG+A++ IA D + P FD++V Q V +FS L
Sbjct: 156 FFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQL 202
Score = 34.7 bits (76), Expect = 0.46
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +2
Query: 368 YYGVISIGTPPQSFKVVFDTGSSNLWV 448
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 62 YYVEMTVGSPPQTLNILVDTGSSNFAV 88
>AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving
enzyme protein.
Length = 501
Score = 47.6 bits (108), Expect = 6e-05
Identities = 35/107 (32%), Positives = 53/107 (49%), Gaps = 4/107 (3%)
Frame = +3
Query: 489 LHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVG-GLKVRRQTFAEAVSEPGL 665
LH Y + S TY + Y G G L TD V++ G V + A++E
Sbjct: 109 LHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDK 168
Query: 666 AFV-AAKFDGILGMAFSTIA--VDHVXPVFDNMVAQGLVQPVFSFYL 797
F+ + ++GILG+A++ IA D + P FD++V Q V +FS L
Sbjct: 169 FFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQL 215
Score = 34.7 bits (76), Expect = 0.46
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +2
Query: 368 YYGVISIGTPPQSFKVVFDTGSSNLWV 448
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein.
Length = 532
Score = 47.6 bits (108), Expect = 6e-05
Identities = 35/107 (32%), Positives = 53/107 (49%), Gaps = 4/107 (3%)
Frame = +3
Query: 489 LHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVG-GLKVRRQTFAEAVSEPGL 665
LH Y + S TY + Y G G L TD V++ G V + A++E
Sbjct: 140 LHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDK 199
Query: 666 AFV-AAKFDGILGMAFSTIA--VDHVXPVFDNMVAQGLVQPVFSFYL 797
F+ + ++GILG+A++ IA D + P FD++V Q V +FS L
Sbjct: 200 FFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQL 246
Score = 34.7 bits (76), Expect = 0.46
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +2
Query: 368 YYGVISIGTPPQSFKVVFDTGSSNLWV 448
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 106 YYVEMTVGSPPQTLNILVDTGSSNFAV 132
>BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 45.2 bits (102), Expect = 3e-04
Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 4/107 (3%)
Frame = +3
Query: 489 LHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVG-GLKVRRQTFAEAVSEPGL 665
LH Y + TY + Y G G L TD V++ G V + A++E
Sbjct: 109 LHRYYQRQLFSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDK 168
Query: 666 AFV-AAKFDGILGMAFSTIA--VDHVXPVFDNMVAQGLVQPVFSFYL 797
F+ + ++GILG+A++ IA D + P FD++V Q V +FS L
Sbjct: 169 FFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQL 215
Score = 34.7 bits (76), Expect = 0.46
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +2
Query: 368 YYGVISIGTPPQSFKVVFDTGSSNLWV 448
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AB177847-1|BAD66825.1| 396|Homo sapiens KIAA1149 splice variant 1
protein.
Length = 396
Score = 41.5 bits (93), Expect = 0.004
Identities = 29/86 (33%), Positives = 46/86 (53%), Gaps = 4/86 (4%)
Frame = +3
Query: 552 IQYGSGSLSGFLSTDDVTVG-GLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFSTIA- 722
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A++ IA
Sbjct: 25 VPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIAR 84
Query: 723 -VDHVXPVFDNMVAQGLVQPVFSFYL 797
D + P FD++V Q V +FS L
Sbjct: 85 PDDSLEPFFDSLVKQTHVPNLFSLQL 110
>AL365205-3|CAM16152.1| 86|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 86
Score = 38.7 bits (86), Expect = 0.028
Identities = 28/70 (40%), Positives = 37/70 (52%), Gaps = 9/70 (12%)
Frame = +2
Query: 215 SVMALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQ 367
+V+ RVPL + K+ R E G E LR KYD + EP++ Y+DA
Sbjct: 18 AVICKQRVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAA 76
Query: 368 YYGVISIGTP 397
Y+G ISIGTP
Sbjct: 77 YFGEISIGTP 86
>AF338816-1|AAK38374.1| 476|Homo sapiens beta-site APP cleaving
enzyme type B protein.
Length = 476
Score = 36.3 bits (80), Expect = 0.15
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 2/80 (2%)
Frame = +3
Query: 489 LHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVG-GLKVRRQTFAEAVSEPGL 665
LH Y + S TY + Y G G L TD V++ G V + A++E
Sbjct: 109 LHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDK 168
Query: 666 AFV-AAKFDGILGMAFSTIA 722
F+ + ++GILG+A++ IA
Sbjct: 169 FFINGSNWEGILGLAYAEIA 188
Score = 34.7 bits (76), Expect = 0.46
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +2
Query: 368 YYGVISIGTPPQSFKVVFDTGSSNLWV 448
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AB050436-1|BAB40931.1| 476|Homo sapiens beta-site APP cleaving
enzyme I-476 protein.
Length = 476
Score = 36.3 bits (80), Expect = 0.15
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 2/80 (2%)
Frame = +3
Query: 489 LHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLSTDDVTVG-GLKVRRQTFAEAVSEPGL 665
LH Y + S TY + Y G G L TD V++ G V + A++E
Sbjct: 109 LHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDK 168
Query: 666 AFV-AAKFDGILGMAFSTIA 722
F+ + ++GILG+A++ IA
Sbjct: 169 FFINGSNWEGILGLAYAEIA 188
Score = 34.7 bits (76), Expect = 0.46
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +2
Query: 368 YYGVISIGTPPQSFKVVFDTGSSNLWV 448
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving
enzyme type C protein.
Length = 457
Score = 34.7 bits (76), Expect = 0.46
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +2
Query: 368 YYGVISIGTPPQSFKVVFDTGSSNLWV 448
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AB089958-1|BAC81826.1| 127|Homo sapiens beta-site APP cleaving
enzyme isoform I-127 protein.
Length = 127
Score = 34.7 bits (76), Expect = 0.46
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +2
Query: 368 YYGVISIGTPPQSFKVVFDTGSSNLWV 448
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AB050438-1|BAB40933.1| 432|Homo sapiens beta-site APP cleaving
enzyme I-432 protein.
Length = 432
Score = 34.7 bits (76), Expect = 0.46
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +2
Query: 368 YYGVISIGTPPQSFKVVFDTGSSNLWV 448
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving
enzyme I-457 protein.
Length = 457
Score = 34.7 bits (76), Expect = 0.46
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +2
Query: 368 YYGVISIGTPPQSFKVVFDTGSSNLWV 448
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AK055141-1|BAB70862.1| 260|Homo sapiens protein ( Homo sapiens
cDNA FLJ30579 fis, clone BRAWH2006989, weakly similar to
DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT (EC
2.7.7.6). ).
Length = 260
Score = 32.7 bits (71), Expect = 1.8
Identities = 20/54 (37%), Positives = 26/54 (48%)
Frame = -2
Query: 600 HHQWRGSRRGCRSRTVSRTGCHSRRTSWTCGCRTCCAAKQAMLV*WHFLEGTQR 439
H+ W GS R C S T S G HS SWT R C + + ++ H L + R
Sbjct: 26 HNSWTGSNRACSSWTGSTRG-HS---SWTGSSRACSSWTGSRMI--HSLRSSNR 73
>AF141344-1|AAG49447.1| 119|Homo sapiens LYST-interacting protein
LIP8 protein.
Length = 119
Score = 32.3 bits (70), Expect = 2.4
Identities = 13/33 (39%), Positives = 16/33 (48%)
Frame = -2
Query: 591 WRGSRRGCRSRTVSRTGCHSRRTSWTCGCRTCC 493
W GS+R C + V + S SW CR CC
Sbjct: 8 WPGSKRECANCRVGTSSWRSSGWSWWKDCRPCC 40
>AK056774-1|BAB71280.1| 256|Homo sapiens protein ( Homo sapiens
cDNA FLJ32212 fis, clone PLACE6003399, weakly similar to
SPIDROIN 1. ).
Length = 256
Score = 31.5 bits (68), Expect = 4.2
Identities = 19/54 (35%), Positives = 23/54 (42%), Gaps = 1/54 (1%)
Frame = +2
Query: 680 QVRRDPRDGLQHYRSGPCXP-GVRQHGGSGTRAARLLVLSQQGPRGRQRAANCC 838
Q RR R G+ G GVR G A Q GPRGR+R+ + C
Sbjct: 172 QTRRGGRGGVNELSGGRMVQAGVRSAAGGEREALASRARGQGGPRGRRRSRDRC 225
>BC041063-1|AAH41063.1| 616|Homo sapiens eyes absent homolog 4
(Drosophila) protein.
Length = 616
Score = 30.7 bits (66), Expect = 7.4
Identities = 28/100 (28%), Positives = 39/100 (39%), Gaps = 11/100 (11%)
Frame = +3
Query: 423 TPDP---PTSGCLPKSATTPTSLVLLHNKYDSRKS--------KTYVANGTQFAIQYGSG 569
TP P P S +P S+ P+S + +N + + +Y A G QY S
Sbjct: 205 TPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSA 264
Query: 570 SLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFD 689
S G T + T G T+ S PGL +FD
Sbjct: 265 STYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFD 304
>BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain
containing 11 protein.
Length = 514
Score = 30.7 bits (66), Expect = 7.4
Identities = 12/26 (46%), Positives = 18/26 (69%)
Frame = -1
Query: 433 GSGVEYHLERLRRRADTDHSVVLSIK 356
G G E+HLER+RR ++++ SIK
Sbjct: 30 GQGAEHHLERIRRSHQKHNAILASIK 55
>AL450270-3|CAI41273.1| 605|Homo sapiens eyes absent homolog 4
(Drosophila) protein.
Length = 605
Score = 30.7 bits (66), Expect = 7.4
Identities = 28/100 (28%), Positives = 39/100 (39%), Gaps = 11/100 (11%)
Frame = +3
Query: 423 TPDP---PTSGCLPKSATTPTSLVLLHNKYDSRKS--------KTYVANGTQFAIQYGSG 569
TP P P S +P S+ P+S + +N + + +Y A G QY S
Sbjct: 194 TPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSA 253
Query: 570 SLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFD 689
S G T + T G T+ S PGL +FD
Sbjct: 254 STYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFD 293
>AL450270-2|CAI41272.1| 639|Homo sapiens eyes absent homolog 4
(Drosophila) protein.
Length = 639
Score = 30.7 bits (66), Expect = 7.4
Identities = 28/100 (28%), Positives = 39/100 (39%), Gaps = 11/100 (11%)
Frame = +3
Query: 423 TPDP---PTSGCLPKSATTPTSLVLLHNKYDSRKS--------KTYVANGTQFAIQYGSG 569
TP P P S +P S+ P+S + +N + + +Y A G QY S
Sbjct: 228 TPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSA 287
Query: 570 SLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFD 689
S G T + T G T+ S PGL +FD
Sbjct: 288 STYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFD 327
>AL121959-1|CAB92069.2| 639|Homo sapiens eyes absent homolog 4
(Drosophila) protein.
Length = 639
Score = 30.7 bits (66), Expect = 7.4
Identities = 28/100 (28%), Positives = 39/100 (39%), Gaps = 11/100 (11%)
Frame = +3
Query: 423 TPDP---PTSGCLPKSATTPTSLVLLHNKYDSRKS--------KTYVANGTQFAIQYGSG 569
TP P P S +P S+ P+S + +N + + +Y A G QY S
Sbjct: 228 TPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSA 287
Query: 570 SLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFD 689
S G T + T G T+ S PGL +FD
Sbjct: 288 STYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFD 327
>AL024497-3|CAI42525.1| 605|Homo sapiens eyes absent homolog 4
(Drosophila) protein.
Length = 605
Score = 30.7 bits (66), Expect = 7.4
Identities = 28/100 (28%), Positives = 39/100 (39%), Gaps = 11/100 (11%)
Frame = +3
Query: 423 TPDP---PTSGCLPKSATTPTSLVLLHNKYDSRKS--------KTYVANGTQFAIQYGSG 569
TP P P S +P S+ P+S + +N + + +Y A G QY S
Sbjct: 194 TPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSA 253
Query: 570 SLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFD 689
S G T + T G T+ S PGL +FD
Sbjct: 254 STYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFD 293
>AL024497-2|CAI42524.1| 639|Homo sapiens eyes absent homolog 4
(Drosophila) protein.
Length = 639
Score = 30.7 bits (66), Expect = 7.4
Identities = 28/100 (28%), Positives = 39/100 (39%), Gaps = 11/100 (11%)
Frame = +3
Query: 423 TPDP---PTSGCLPKSATTPTSLVLLHNKYDSRKS--------KTYVANGTQFAIQYGSG 569
TP P P S +P S+ P+S + +N + + +Y A G QY S
Sbjct: 228 TPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSA 287
Query: 570 SLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFD 689
S G T + T G T+ S PGL +FD
Sbjct: 288 STYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFD 327
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 119,424,628
Number of Sequences: 237096
Number of extensions: 2589130
Number of successful extensions: 7499
Number of sequences better than 10.0: 81
Number of HSP's better than 10.0 without gapping: 6708
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7415
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11437206932
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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