Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP15_F_G19
(881 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu... 227 2e-58
UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ... 210 3e-53
UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri... 206 8e-52
UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA... 203 4e-51
UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|... 186 9e-46
UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1... 186 9e-46
UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ... 185 1e-45
UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep... 185 2e-45
UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;... 183 5e-45
UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13... 182 1e-44
UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ... 181 2e-44
UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ... 179 8e-44
UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n... 179 1e-43
UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p... 178 1e-43
UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ... 176 5e-43
UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18... 176 7e-43
UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica... 174 2e-42
UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|... 174 3e-42
UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA... 173 7e-42
UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ... 172 9e-42
UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or... 171 2e-41
UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E... 168 2e-40
UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|... 167 3e-40
UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt... 166 6e-40
UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb... 165 1e-39
UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi... 165 1e-39
UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin... 165 2e-39
UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti... 163 5e-39
UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons... 162 9e-39
UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep... 161 2e-38
UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=... 159 9e-38
UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R... 159 1e-37
UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ... 158 2e-37
UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:... 157 3e-37
UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase fam... 156 6e-37
UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota... 156 8e-37
UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;... 155 1e-36
UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct... 155 1e-36
UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+... 155 1e-36
UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ... 154 3e-36
UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str... 154 3e-36
UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:... 153 4e-36
UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l... 95 7e-36
UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;... 152 1e-35
UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal... 152 1e-35
UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve... 152 1e-35
UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ... 151 2e-35
UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ... 151 2e-35
UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d... 151 3e-35
UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R... 150 4e-35
UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; ... 149 7e-35
UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+... 149 9e-35
UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re... 148 2e-34
UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta... 148 2e-34
UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27... 147 4e-34
UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red... 146 5e-34
UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi... 146 7e-34
UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re... 145 1e-33
UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ... 145 1e-33
UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 144 2e-33
UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta... 144 2e-33
UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct... 144 3e-33
UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio... 144 3e-33
UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ... 143 5e-33
UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di... 143 5e-33
UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ... 143 6e-33
UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A... 143 6e-33
UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10... 142 1e-32
UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=... 142 1e-32
UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ... 141 2e-32
UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium... 140 3e-32
UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste... 140 4e-32
UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 140 6e-32
UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor... 140 6e-32
UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald... 140 6e-32
UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam... 139 7e-32
UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R... 139 7e-32
UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;... 138 1e-31
UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt... 138 2e-31
UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ... 138 2e-31
UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ... 138 2e-31
UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r... 138 2e-31
UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ... 136 5e-31
UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ... 131 6e-31
UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ... 136 9e-31
UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb... 135 1e-30
UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam... 135 1e-30
UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 135 1e-30
UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re... 135 2e-30
UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re... 135 2e-30
UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lambl... 134 2e-30
UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam... 134 2e-30
UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 134 3e-30
UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB... 134 3e-30
UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 134 4e-30
UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7... 133 5e-30
UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org... 133 5e-30
UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 133 6e-30
UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop... 132 9e-30
UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc... 132 1e-29
UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r... 132 1e-29
UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti... 132 1e-29
UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy... 132 1e-29
UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ... 132 1e-29
UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ... 131 2e-29
UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam... 131 2e-29
UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ... 131 3e-29
UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 130 6e-29
UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|... 129 8e-29
UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini... 95 1e-28
UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ... 128 1e-28
UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:... 128 2e-28
UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 128 2e-28
UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac... 128 2e-28
UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno... 128 2e-28
UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar... 127 3e-28
UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci... 127 4e-28
UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ... 127 4e-28
UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ... 127 4e-28
UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag... 126 6e-28
UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct... 126 7e-28
UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E... 126 7e-28
UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ... 126 1e-27
UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several... 125 1e-27
UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4... 125 2e-27
UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=... 125 2e-27
UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7... 125 2e-27
UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve... 124 4e-27
UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase... 124 4e-27
UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ... 123 5e-27
UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 123 5e-27
UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam... 123 5e-27
UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct... 123 7e-27
UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:... 123 7e-27
UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ... 122 9e-27
UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop... 122 9e-27
UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str... 122 1e-26
UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 122 2e-26
UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ... 121 2e-26
UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l... 121 2e-26
UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep... 120 4e-26
UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=... 120 4e-26
UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet... 120 4e-26
UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;... 119 9e-26
UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam... 119 9e-26
UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea... 119 1e-25
UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r... 118 1e-25
UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam... 118 1e-25
UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3... 118 1e-25
UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct... 118 1e-25
UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam... 118 2e-25
UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil... 118 3e-25
UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n... 118 3e-25
UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re... 117 5e-25
UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ... 116 6e-25
UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ... 116 6e-25
UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=... 116 6e-25
UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; S... 116 6e-25
UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl... 116 8e-25
UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac... 116 1e-24
UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal... 115 1e-24
UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 114 2e-24
UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r... 114 2e-24
UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str... 114 2e-24
UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r... 114 3e-24
UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,... 113 4e-24
UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 113 4e-24
UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=... 113 4e-24
UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1... 113 6e-24
UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac... 113 6e-24
UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red... 113 6e-24
UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ... 113 7e-24
UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ... 113 7e-24
UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea... 113 7e-24
UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 113 7e-24
UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:... 111 2e-23
UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;... 111 2e-23
UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 111 2e-23
UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ... 111 2e-23
UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyled... 111 2e-23
UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ... 111 2e-23
UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter... 111 2e-23
UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami... 111 2e-23
UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li... 111 3e-23
UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 111 3e-23
UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam... 110 4e-23
UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O... 110 5e-23
UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ... 109 1e-22
UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ... 108 2e-22
UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter... 107 4e-22
UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium... 107 4e-22
UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve... 107 5e-22
UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1... 107 5e-22
UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ... 106 6e-22
UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct... 106 9e-22
UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 106 9e-22
UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ... 105 1e-21
UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ... 105 1e-21
UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba... 105 1e-21
UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil... 105 1e-21
UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 105 1e-21
UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ... 105 2e-21
UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li... 104 3e-21
UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ... 104 3e-21
UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep... 104 3e-21
UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldeh... 104 3e-21
UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act... 103 5e-21
UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ... 103 5e-21
UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ... 103 5e-21
UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm... 103 6e-21
UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 103 6e-21
UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta... 103 6e-21
UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Gri... 91 6e-21
UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami... 103 8e-21
UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep... 103 8e-21
UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec... 103 8e-21
UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li... 102 1e-20
UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami... 102 1e-20
UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101... 102 1e-20
UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium... 102 1e-20
UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; ... 102 1e-20
UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n... 101 2e-20
UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 101 2e-20
UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v... 101 2e-20
UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria... 101 2e-20
UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ... 101 3e-20
UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ... 101 3e-20
UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 101 3e-20
UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez... 100 4e-20
UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ... 100 6e-20
UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ... 100 6e-20
UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1... 99 7e-20
UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ... 99 7e-20
UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Re... 100 1e-19
UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc... 99 1e-19
UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik... 99 1e-19
UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc... 99 2e-19
UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ... 98 2e-19
UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez... 98 2e-19
UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy... 98 3e-19
UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;... 97 4e-19
UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc... 97 4e-19
UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteri... 97 4e-19
UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom... 97 7e-19
UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep... 97 7e-19
UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam... 96 9e-19
UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace... 96 9e-19
UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep... 95 2e-18
UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 95 2e-18
UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 95 2e-18
UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ... 94 5e-18
UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ... 93 6e-18
UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;... 93 8e-18
UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=... 92 1e-17
UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 92 1e-17
UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam... 92 2e-17
UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; ... 91 3e-17
UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas... 91 3e-17
UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 91 3e-17
UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ... 91 3e-17
UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r... 91 5e-17
UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte... 91 5e-17
UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re... 90 6e-17
UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1; ... 90 6e-17
UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo... 90 8e-17
UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica... 67 1e-16
UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob... 89 1e-16
UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1; ... 89 1e-16
UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; ... 89 1e-16
UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 89 2e-16
UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc... 88 2e-16
UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 87 4e-16
UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve... 87 6e-16
UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam... 87 7e-16
UniRef50_Q9V2P1 Cluster: Myo-inositol degradation; n=5; Archaea|... 87 7e-16
UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 86 1e-15
UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Try... 85 2e-15
UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami... 85 3e-15
UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba... 84 4e-15
UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pac... 84 4e-15
UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ... 84 4e-15
UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; ... 83 7e-15
UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ... 83 1e-14
UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasi... 82 2e-14
UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam... 81 3e-14
UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Sac... 81 3e-14
UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 81 4e-14
UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_030017... 80 8e-14
UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ... 79 1e-13
UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase fami... 79 1e-13
UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; ... 79 2e-13
UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Hom... 79 2e-13
UniRef50_Q89RG2 Cluster: Aldo/keto reductase; n=11; Bacteria|Rep... 78 3e-13
UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,... 78 3e-13
UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; ... 78 3e-13
UniRef50_A0LJ47 Cluster: Aldo/keto reductase; n=1; Syntrophobact... 77 5e-13
UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreduc... 77 6e-13
UniRef50_A3H9Y8 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 77 8e-13
UniRef50_A3DNU7 Cluster: Aldo/keto reductase; n=3; Desulfurococc... 77 8e-13
UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspe... 76 1e-12
UniRef50_Q8EUX1 Cluster: Aldo/keto reductase family oxidoreducta... 76 1e-12
UniRef50_Q5KPU6 Cluster: Putative uncharacterized protein; n=2; ... 75 2e-12
UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriac... 75 2e-12
UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ... 75 2e-12
UniRef50_Q97V56 Cluster: Dehydrogenase; n=8; Thermoprotei|Rep: D... 75 2e-12
UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 74 4e-12
UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cel... 74 6e-12
UniRef50_A1CHK2 Cluster: Aldose 1-epimerase, putative; n=11; Pez... 74 6e-12
UniRef50_Q1IQ78 Cluster: Aldo/keto reductase; n=1; Acidobacteria... 73 7e-12
UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces cere... 73 1e-11
UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ... 73 1e-11
UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; ... 72 2e-11
UniRef50_Q7NK63 Cluster: Gll1617 protein; n=1; Gloeobacter viola... 71 3e-11
UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfata... 71 3e-11
UniRef50_Q6NKP1 Cluster: At5g53580; n=18; cellular organisms|Rep... 71 5e-11
UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG054... 71 5e-11
UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; ... 70 7e-11
UniRef50_Q04TM6 Cluster: Aryl-alcohol dehydrogenase-related oxid... 69 1e-10
UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces cap... 69 2e-10
UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella... 69 2e-10
UniRef50_A5V463 Cluster: Aldo/keto reductase; n=1; Sphingomonas ... 69 2e-10
UniRef50_P76234 Cluster: Uncharacterized protein yeaE; n=39; Bac... 69 2e-10
UniRef50_A4M6J9 Cluster: Aldo/keto reductase; n=1; Petrotoga mob... 68 3e-10
UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyc... 68 4e-10
UniRef50_A7HEV1 Cluster: Aldo/keto reductase; n=13; Bacteria|Rep... 66 8e-10
UniRef50_Q5FHT2 Cluster: Aldehyde reductase; n=4; Lactobacillus|... 66 1e-09
UniRef50_Q391C9 Cluster: Aldo/keto reductase; n=10; Proteobacter... 66 1e-09
UniRef50_UPI0000DAE567 Cluster: hypothetical protein Rgryl_01000... 66 1e-09
UniRef50_A6R5B4 Cluster: NAD(P)H-dependent D-xylose reductase; n... 66 1e-09
UniRef50_P80874 Cluster: General stress protein 69; n=16; cellul... 66 1e-09
UniRef50_Q3ZWR6 Cluster: Oxidoreductase, aldo reductase; n=3; De... 65 2e-09
UniRef50_Q1EZH4 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 65 2e-09
UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ... 65 3e-09
UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4; The... 65 3e-09
UniRef50_Q0GU15 Cluster: ORF28; n=3; Bacteria|Rep: ORF28 - Lacto... 64 3e-09
UniRef50_Q8YXI8 Cluster: All1225 protein; n=9; Cyanobacteria|Rep... 64 5e-09
UniRef50_A7LSN6 Cluster: Putative uncharacterized protein; n=3; ... 64 6e-09
UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; ... 63 8e-09
UniRef50_UPI00005F9591 Cluster: COG0656: Aldo/keto reductases, r... 63 1e-08
UniRef50_Q8EVP7 Cluster: Putative oxidoreductase; n=3; Bacteria|... 62 1e-08
UniRef50_Q21EY6 Cluster: Aldo/keto reductase; n=1; Saccharophagu... 62 1e-08
UniRef50_Q94A68 Cluster: Uncharacterized oxidoreductase At1g0669... 62 1e-08
UniRef50_UPI00015BB020 Cluster: aldo/keto reductase; n=1; Ignico... 62 2e-08
UniRef50_Q88TP1 Cluster: Oxidoreductase; n=3; Bacteria|Rep: Oxid... 62 2e-08
UniRef50_Q18903 Cluster: Putative uncharacterized protein C56G3.... 61 3e-08
UniRef50_A6QVW8 Cluster: Predicted protein; n=1; Ajellomyces cap... 61 3e-08
UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3; Lei... 60 6e-08
UniRef50_Q09923 Cluster: Aldo-keto reductase yakc [NADP+]; n=13;... 60 6e-08
UniRef50_Q8Y5Q1 Cluster: Lmo2005 protein; n=34; cellular organis... 59 1e-07
UniRef50_Q54CX8 Cluster: Putative uncharacterized protein; n=1; ... 59 1e-07
UniRef50_Q2H1Q3 Cluster: Putative uncharacterized protein; n=1; ... 59 1e-07
UniRef50_Q8PN61 Cluster: Oxidoreductase; n=5; Proteobacteria|Rep... 59 2e-07
UniRef50_Q60BI7 Cluster: Oxidoreductase, aldo/keto reductase fam... 59 2e-07
UniRef50_Q55493 Cluster: Auxin-induced protein; n=2; Bacteria|Re... 59 2e-07
UniRef50_A2UBC7 Cluster: Aldo/keto reductase; n=3; cellular orga... 59 2e-07
UniRef50_A4R217 Cluster: Putative uncharacterized protein; n=1; ... 59 2e-07
UniRef50_A1S0T5 Cluster: Aldo/keto reductase; n=2; Thermoprotei|... 59 2e-07
UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreducta... 58 3e-07
UniRef50_A6C9W8 Cluster: Aldo/keto reductase; n=2; Planctomyceta... 58 3e-07
UniRef50_Q97UJ7 Cluster: Oxidoreductase; n=4; Archaea|Rep: Oxido... 58 3e-07
UniRef50_Q660Z5 Cluster: Aldose reductase, putative; n=3; Borrel... 58 4e-07
UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa... 58 4e-07
UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1; ... 56 9e-07
UniRef50_P46905 Cluster: Uncharacterized oxidoreductase yccK; n=... 56 9e-07
UniRef50_Q1VSU3 Cluster: Aryl-alcohol dehydrogenase; n=1; Psychr... 56 1e-06
UniRef50_Q0TYC7 Cluster: Predicted protein; n=1; Phaeosphaeria n... 56 1e-06
UniRef50_A4RPC9 Cluster: Putative uncharacterized protein; n=1; ... 56 2e-06
UniRef50_A7RPK2 Cluster: Predicted protein; n=1; Nematostella ve... 55 2e-06
UniRef50_Q31SB1 Cluster: Putative uncharacterized protein; n=2; ... 55 3e-06
UniRef50_Q31DD1 Cluster: Aldo/keto reductase family; n=5; Prochl... 55 3e-06
UniRef50_Q3WEJ4 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 55 3e-06
UniRef50_A6VXX8 Cluster: Aldo/keto reductase; n=2; Marinomonas|R... 55 3e-06
UniRef50_A1SLH1 Cluster: Aldo/keto reductase; n=27; Bacteria|Rep... 55 3e-06
UniRef50_Q55FL2 Cluster: Putative uncharacterized protein; n=1; ... 55 3e-06
UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; ... 55 3e-06
UniRef50_A7BLU0 Cluster: Aldo/keto reductase family; n=1; Beggia... 54 4e-06
UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1; ... 54 4e-06
UniRef50_A7T149 Cluster: Predicted protein; n=1; Nematostella ve... 54 4e-06
UniRef50_Q46851 Cluster: Uncharacterized protein yghZ; n=126; Ba... 54 4e-06
UniRef50_Q2J8X9 Cluster: Aldo/keto reductase; n=3; Frankia|Rep: ... 54 5e-06
UniRef50_A6FYX9 Cluster: Oxidoreductase; n=1; Plesiocystis pacif... 54 6e-06
UniRef50_A3U5K6 Cluster: Oxidoreductase, aldo/keto reductase fam... 54 6e-06
UniRef50_A6RYK4 Cluster: Putative uncharacterized protein; n=1; ... 54 6e-06
UniRef50_Q2NGB6 Cluster: Predicted oxidoreductase; n=1; Methanos... 54 6e-06
UniRef50_A0RYR0 Cluster: Oxidoreductase; n=2; cellular organisms... 54 6e-06
UniRef50_A6X3I0 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 53 8e-06
UniRef50_Q55ML8 Cluster: Putative uncharacterized protein; n=2; ... 53 8e-06
UniRef50_A7AFQ7 Cluster: Putative uncharacterized protein; n=1; ... 53 1e-05
UniRef50_Q9W2X0 Cluster: CG32688-PA, isoform A; n=4; Sophophora|... 53 1e-05
UniRef50_A7RXR1 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 53 1e-05
UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose red... 52 1e-05
UniRef50_Q81RN9 Cluster: Oxidoreductase, aldo/keto reductase fam... 52 1e-05
UniRef50_A5CYR4 Cluster: Predicted oxidoreductases; n=2; Clostri... 52 1e-05
UniRef50_Q27ST7 Cluster: Oxidoreductase; n=2; Eukaryota|Rep: Oxi... 52 1e-05
UniRef50_P77256 Cluster: Uncharacterized oxidoreductase ydjG; n=... 52 1e-05
UniRef50_Q2BBT9 Cluster: Probable oxidoreductase protein; n=2; B... 52 2e-05
UniRef50_Q03I00 Cluster: Aryl-alcohol dehydrogenase related enzy... 52 3e-05
UniRef50_Q2JHT1 Cluster: Aldo/keto reductase Tas; n=25; cellular... 51 3e-05
UniRef50_Q1FGT1 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 51 3e-05
UniRef50_A4AP98 Cluster: Putative uncharacterized protein; n=1; ... 51 3e-05
UniRef50_UPI0000DB6B5C Cluster: PREDICTED: similar to glutamate-... 51 4e-05
UniRef50_Q38Z15 Cluster: Putative aldo/keto reductase; n=2; Bact... 51 4e-05
UniRef50_Q08NK7 Cluster: Aldo/keto reductase; n=1; Stigmatella a... 51 4e-05
UniRef50_A4CIJ8 Cluster: Putative uncharacterized protein; n=2; ... 51 4e-05
UniRef50_Q67NQ1 Cluster: Oxidoreductase; n=1; Symbiobacterium th... 50 6e-05
UniRef50_A5BYJ4 Cluster: Putative uncharacterized protein; n=1; ... 50 6e-05
UniRef50_Q1FEK2 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 50 8e-05
UniRef50_A1RA11 Cluster: Oxidoreductase, aldo/keto reductase fam... 50 8e-05
UniRef50_A0Q648 Cluster: Aldo/keto reductase family protein; n=1... 50 8e-05
UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative... 50 8e-05
UniRef50_Q4WE75 Cluster: Aldehyde reductase (GliO), putative; n=... 50 8e-05
UniRef50_Q0CV71 Cluster: Putative uncharacterized protein; n=2; ... 50 8e-05
UniRef50_A6SUJ2 Cluster: Uncharacterized conserved protein; n=2;... 50 1e-04
UniRef50_UPI00003C85A8 Cluster: hypothetical protein Faci_030001... 49 1e-04
UniRef50_Q5KYH6 Cluster: K+ channel beta subunit; n=5; Bacteria|... 49 1e-04
UniRef50_A7HL79 Cluster: Aldo/keto reductase; n=1; Fervidobacter... 49 1e-04
UniRef50_A7PNT1 Cluster: Chromosome chr8 scaffold_23, whole geno... 49 1e-04
UniRef50_Q5ZRR0 Cluster: Aldo/keto reductase; n=3; Legionella pn... 49 2e-04
UniRef50_Q93KW0 Cluster: Putative oxidoreductase; n=1; Streptomy... 49 2e-04
UniRef50_Q03UP2 Cluster: Aryl-alcohol dehydrogenase family enzym... 49 2e-04
UniRef50_A7GIW7 Cluster: Oxidoreductase, aldo/keto reductase fam... 49 2e-04
UniRef50_A6XQ31 Cluster: Putative uncharacterized protein; n=1; ... 49 2e-04
UniRef50_Q1GHE2 Cluster: Aldo/keto reductase; n=8; Alphaproteoba... 48 2e-04
UniRef50_Q0B0F0 Cluster: Oxidoreductase; n=1; Syntrophomonas wol... 48 2e-04
UniRef50_Q97UG6 Cluster: Oxidoreductase; n=5; Archaea|Rep: Oxido... 48 2e-04
UniRef50_Q9X0R5 Cluster: Oxidoreductase, aldo/keto reductase fam... 48 3e-04
UniRef50_A7B2Y7 Cluster: Putative uncharacterized protein; n=1; ... 48 3e-04
UniRef50_Q88ZU3 Cluster: Oxidoreductase; n=1; Lactobacillus plan... 48 4e-04
UniRef50_A6CMV7 Cluster: Putative uncharacterized protein; n=2; ... 48 4e-04
UniRef50_Q7D3N9 Cluster: AGR_pAT_274p; n=3; Proteobacteria|Rep: ... 47 6e-04
UniRef50_A0QHX8 Cluster: General stress protein 69; n=2; Mycobac... 47 6e-04
UniRef50_Q7Q0Y6 Cluster: ENSANGP00000006086; n=7; Coelomata|Rep:... 47 6e-04
UniRef50_Q2NFN7 Cluster: Predicted oxidoreductase; n=1; Methanos... 47 6e-04
UniRef50_Q8R6G2 Cluster: Oxidoreductase; n=1; Fusobacterium nucl... 47 7e-04
UniRef50_Q3I1P2 Cluster: Aldo-keto oxidoreductase; n=6; Bacteria... 47 7e-04
UniRef50_Q097V7 Cluster: MocA; n=1; Stigmatella aurantiaca DW4/3... 47 7e-04
UniRef50_Q00T51 Cluster: Aldo/keto reductase; n=2; Ostreococcus|... 47 7e-04
UniRef50_Q5ASJ7 Cluster: Putative uncharacterized protein; n=1; ... 47 7e-04
UniRef50_Q97ZZ1 Cluster: Oxidoreductase; n=4; Sulfolobaceae|Rep:... 47 7e-04
UniRef50_P42972 Cluster: Uncharacterized oxidoreductase ycsN; n=... 47 7e-04
UniRef50_Q1U6R9 Cluster: Aldo/keto reductase; n=25; Bacilli|Rep:... 46 0.001
UniRef50_Q0LKQ4 Cluster: Aldo/keto reductase; n=1; Herpetosiphon... 46 0.001
UniRef50_A1VNV6 Cluster: Aldo/keto reductase precursor; n=7; Pro... 46 0.001
UniRef50_Q87SA8 Cluster: Oxidoreductase Tas, aldo/keto reductase... 46 0.001
UniRef50_Q13GB1 Cluster: Aldo/keto reductase; n=1; Burkholderia ... 46 0.001
UniRef50_Q034L5 Cluster: Aryl-alcohol dehydrogenase related enzy... 46 0.001
UniRef50_A0K203 Cluster: Aldo/keto reductase; n=2; Arthrobacter|... 46 0.001
UniRef50_A1CCJ1 Cluster: Aldo/keto reductase; n=2; Trichocomacea... 46 0.001
UniRef50_A3K469 Cluster: Aldo/keto reductase; n=3; Rhodobacterac... 46 0.002
UniRef50_A1SY15 Cluster: Aldo/keto reductase; n=1; Psychromonas ... 46 0.002
UniRef50_A0ZZJ3 Cluster: Oxidoreductase; n=2; Bifidobacterium ad... 46 0.002
UniRef50_A0JVH3 Cluster: Aldo/keto reductase; n=17; Bacteria|Rep... 46 0.002
UniRef50_A0GAJ5 Cluster: Aldo/keto reductase precursor; n=9; Pro... 46 0.002
UniRef50_O43448 Cluster: Voltage-gated potassium channel subunit... 46 0.002
UniRef50_Q8UIN0 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 45 0.002
UniRef50_Q8VV02 Cluster: Putative oxidoreductase; n=1; Streptomy... 45 0.002
UniRef50_Q0LP88 Cluster: Aldo/keto reductase; n=4; Bacteria|Rep:... 45 0.002
UniRef50_A6LWU9 Cluster: Aldo/keto reductase; n=3; Clostridium|R... 45 0.002
UniRef50_A6C2P2 Cluster: Oxidoreductase, aldo/keto reductase fam... 45 0.002
UniRef50_A5FZX7 Cluster: Aldo/keto reductase precursor; n=4; Bac... 45 0.002
UniRef50_A5EX65 Cluster: Aldo/keto reductase family protein; n=1... 45 0.002
UniRef50_Q84M96 Cluster: At1g60680; n=19; cellular organisms|Rep... 45 0.002
UniRef50_Q6GIV4 Cluster: Aldo/keto reductase family protein; n=1... 45 0.003
UniRef50_Q3AD20 Cluster: Oxidoreductase, aldo/keto reductase fam... 45 0.003
UniRef50_P73573 Cluster: Sll0867 protein; n=15; Bacteria|Rep: Sl... 45 0.003
UniRef50_A0LHW7 Cluster: Aldo/keto reductase precursor; n=1; Syn... 45 0.003
UniRef50_Q75DD3 Cluster: ABR094Wp; n=1; Eremothecium gossypii|Re... 45 0.003
UniRef50_A1DD54 Cluster: Aldo/keto reductase; n=3; Trichocomacea... 45 0.003
UniRef50_Q8YAN3 Cluster: Lmo0084 protein; n=11; Listeria monocyt... 44 0.004
UniRef50_A6W292 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 44 0.004
UniRef50_A5VEK4 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 44 0.004
UniRef50_A4MAE7 Cluster: Aldo/keto reductase; n=1; Petrotoga mob... 44 0.004
UniRef50_A4A767 Cluster: Aldo/keto reductase/Endoribonuclease L-... 44 0.004
UniRef50_Q9ZUX0 Cluster: Expressed protein; n=11; cellular organ... 44 0.004
UniRef50_A6SJ74 Cluster: Putative uncharacterized protein; n=1; ... 44 0.004
UniRef50_Q8PVL5 Cluster: Oxidoreductase, ALDO/KETO reductase fam... 44 0.004
UniRef50_A3H9H5 Cluster: Aldo/keto reductase; n=2; Archaea|Rep: ... 44 0.004
UniRef50_Q4SFJ7 Cluster: Chromosome 7 SCAF14601, whole genome sh... 44 0.005
UniRef50_Q6XUT6 Cluster: Oxido-reductase/dehydratase; n=3; Bacte... 44 0.005
UniRef50_A6VXU3 Cluster: Aldo/keto reductase; n=14; Proteobacter... 44 0.005
UniRef50_Q966L2 Cluster: Putative uncharacterized protein; n=2; ... 44 0.005
UniRef50_Q8TTK4 Cluster: Aldo/keto reductase; n=28; cellular org... 44 0.005
UniRef50_A7CVG9 Cluster: Aldo/keto reductase; n=1; Opitutaceae b... 44 0.007
UniRef50_A4ABU8 Cluster: Oxidoreductase; n=1; Congregibacter lit... 44 0.007
UniRef50_A3I0G0 Cluster: Oxidoreductase; n=1; Algoriphagus sp. P... 44 0.007
UniRef50_A1RJL6 Cluster: Aldo/keto reductase; n=37; Bacteria|Rep... 44 0.007
UniRef50_Q338B1 Cluster: Auxin-induced protein PCNT115, putative... 44 0.007
UniRef50_Q8G7F7 Cluster: Possible oxidoreductase of the aldo/ket... 43 0.009
UniRef50_Q022Y6 Cluster: Aldo/keto reductase precursor; n=2; Sol... 43 0.009
UniRef50_A6WAE5 Cluster: Aldo/keto reductase; n=1; Kineococcus r... 43 0.009
UniRef50_A5FAZ9 Cluster: Aldo/keto reductase; n=1; Flavobacteriu... 43 0.009
UniRef50_P49261 Cluster: Rho beta-crystallin; n=1; Lepidodactylu... 43 0.009
UniRef50_Q8A955 Cluster: Aldo/keto reductase; n=8; Bacteroidales... 43 0.012
UniRef50_Q8A1P5 Cluster: Putative oxidoreductase; n=3; Bacteroid... 43 0.012
UniRef50_Q0AL14 Cluster: Aldo/keto reductase; n=1; Maricaulis ma... 43 0.012
UniRef50_Q01U06 Cluster: Aldo/keto reductase; n=1; Solibacter us... 43 0.012
UniRef50_Q2UHM0 Cluster: Predicted protein; n=1; Aspergillus ory... 43 0.012
UniRef50_A4QYA4 Cluster: Putative uncharacterized protein; n=1; ... 43 0.012
UniRef50_A3LSR5 Cluster: D-threo-aldose 1-dehydrogenase; n=5; Sa... 43 0.012
UniRef50_A7D5V2 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 43 0.012
>UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase
precursor; n=1; Spodoptera littoralis|Rep:
3-dehydroecdysone 3beta-reductase precursor - Spodoptera
littoralis (Egyptian cotton leafworm)
Length = 345
Score = 227 bits (556), Expect = 2e-58
Identities = 113/267 (42%), Positives = 165/267 (61%), Gaps = 1/267 (0%)
Frame = +3
Query: 78 AGFLFCLSALCFTSADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY 257
A F+ L+ SA + VP L++ + +P +ALGT+LG G V V+
Sbjct: 4 ASFILLLACCGAMSATIDVPMLKMLNDREMPAIALGTYLGFDKGGAVTSKDKQLRNVVMQ 63
Query: 258 ALEAGYTHIDTAYKYGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALR 434
A++ GY H DTA Y E +VG A+ K EG +KRE +F+TTKLWN++H+REQV A++
Sbjct: 64 AIDLGYRHFDTAAIYNTEAEVGEAIRMKIDEGVIKREDVFLTTKLWNTHHKREQVAVAMK 123
Query: 435 KSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQ 614
++L L+YVDL+L+HWPIA+ E D N D+L+TWR + KLG TKSIG+SNFN+
Sbjct: 124 ETLNKTGLDYVDLFLMHWPIALNE-DYSHSNTDYLETWRATEEMVKLGYTKSIGLSNFNK 182
Query: 615 EQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAP 794
Q+ ++ KP ALQIE++ + Q +L + ++ I+VM Y+PFGSL + P
Sbjct: 183 LQVATVLQECTIKPVALQIEVHPQIIQEDLITYAKDEGIIVMGYSPFGSLV-KRFGMDLP 241
Query: 795 PPRIDDERLVGIAQKYNKTVPQVALRF 875
P++DD L +A+KY KT Q+ LR+
Sbjct: 242 GPKMDDPVLTSLAKKYEKTPAQIVLRW 268
>UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 321
Score = 210 bits (514), Expect = 3e-53
Identities = 108/260 (41%), Positives = 159/260 (61%), Gaps = 12/260 (4%)
Frame = +3
Query: 132 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 311
V + LS G +PV+ LGTW G +V E AV A++AGY H D A YG E
Sbjct: 5 VDEITLSDGNKVPVLGLGTWQGGNDPDEV-------ENAVKLAIDAGYRHFDCASFYGNE 57
Query: 312 DQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 488
++G+A+ +K +G+ KRE +F+ TK+WN ++E V+ A ++SL+ L L Y+DLYL+HW
Sbjct: 58 AEIGKAIQEKIDQGVVKREDLFVVTKVWNDERKQELVVAACKRSLKKLGLGYIDLYLVHW 117
Query: 489 PIA---MFE-------NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 638
P + +++ N LD VD+++TWRGM + KLGLT+SIG+SNFN +Q+ R+++
Sbjct: 118 PFSYPILYQYIVLPTYNAVTLDEVDYIETWRGMEECIKLGLTRSIGVSNFNSQQLTRLLE 177
Query: 639 SGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKA-QPXAPPPRIDDE 815
S KP QIEL++NL Q +L +FC I V Y+PFG+ + QP +
Sbjct: 178 SASIKPVMNQIELHINLNQKKLREFCASKSIAVTGYSPFGAPGRNNVFQPAGADISLQSP 237
Query: 816 RLVGIAQKYNKTVPQVALRF 875
+ GIA+KYNKT Q+ LR+
Sbjct: 238 VITGIAKKYNKTNAQIVLRY 257
>UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1;
Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase -
Trichoplusia ni (Cabbage looper)
Length = 308
Score = 206 bits (502), Expect = 8e-52
Identities = 117/249 (46%), Positives = 154/249 (61%), Gaps = 2/249 (0%)
Frame = +3
Query: 135 PTLQLSSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 311
P QL+ G IP +ALGT+ G PK QAV++A++AGY HIDTA YG E
Sbjct: 25 PLKQLNDGNAIPSLALGTFGFGDIPK---------VRQAVLWAIQAGYRHIDTAALYGNE 75
Query: 312 DQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 488
++VG+ + +GL KRE +F+TTKLWN H R QV+PALR+SL L L YVDLYLIH
Sbjct: 76 EEVGKGIADAIQQGLVKREELFVTTKLWNDKHGRHQVVPALRESLTKLGLSYVDLYLIHS 135
Query: 489 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 668
P A EN +D +D L+TW GM +AKKLGL KSIG+SNF+ + R+I P+ Q
Sbjct: 136 PEATNENGDPVD-IDVLNTWNGMEEAKKLGLAKSIGVSNFDTALLDRLIAGSNTVPAVNQ 194
Query: 669 IELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNK 848
IE++ + Q +L E I VMAY+PFG + S+ P +D + IA+KYNK
Sbjct: 195 IEVHPSKTQEKLVADSHERGIEVMAYSPFG-FYVSRGSHNNPVK--NDRTVADIARKYNK 251
Query: 849 TVPQVALRF 875
TV QV +R+
Sbjct: 252 TVNQVLVRY 260
>UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
GA10458-PA - Nasonia vitripennis
Length = 569
Score = 203 bits (496), Expect = 4e-51
Identities = 105/259 (40%), Positives = 160/259 (61%), Gaps = 11/259 (4%)
Frame = +3
Query: 132 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 311
VPT+ + G +P++ LGT+L +P G+V + AV YA+E GY H+DTA+ Y E
Sbjct: 3 VPTVTFNDGYKMPMIGLGTFLS-KP-GEVAE-------AVKYAIEVGYRHVDTAFFYENE 53
Query: 312 DQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 488
++G A+ +K ++G +KRE IF+TTKLW + H+ ++V+PA +KSLENL +Y+DL+L+HW
Sbjct: 54 KEIGSAIREKINDGTIKREDIFVTTKLWCNSHKEDEVVPACKKSLENLGFDYIDLFLVHW 113
Query: 489 PIAMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 638
P A D L + D+L+TW+GM + K+ GL +SIG+SNFN EQI R++
Sbjct: 114 PFAFKSGDALTPRDAAGKIEFSDTDYLETWKGMEECKRQGLARSIGLSNFNSEQIARLLS 173
Query: 639 SGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
S KP Q+E+ +NL Q L +FC++++I V ++P G P D+ +
Sbjct: 174 SAKIKPVNNQVEVTMNLNQKPLIEFCKKHEITVTGFSPLGR--PGNRH--GIQNLWDEPQ 229
Query: 819 LVGIAQKYNKTVPQVALRF 875
+ +AQKY KT +A RF
Sbjct: 230 IQKLAQKYKKTPANIACRF 248
Score = 175 bits (425), Expect = 2e-42
Identities = 88/209 (42%), Positives = 128/209 (61%), Gaps = 8/209 (3%)
Frame = +3
Query: 273 YTHIDTAYKYGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLEN 449
Y HIDTAY Y E +G A+ +K +G +KRE +F+TTKL H+ +V+PA ++SL +
Sbjct: 301 YRHIDTAYLYDNEKYIGNAIREKIKDGTVKREDLFVTTKLSYYAHKESEVVPACKQSLND 360
Query: 450 LNLEYVDLYLIHWPIAMF-------ENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNF 608
L L+Y+DLYLIHWPI + LL + D+L+TW+GM + K+ GL +SIG+SNF
Sbjct: 361 LGLDYIDLYLIHWPIRRYFRHNKNASGKLLLSDTDYLETWKGMEECKRQGLARSIGVSNF 420
Query: 609 NQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPX 788
N EQI R++++ KP Q+E++L L Q L +FC+++DI V Y+P G P
Sbjct: 421 NSEQITRLLEAAKIKPVNNQVEVSLKLNQKALIEFCKKHDITVTGYSPLGR--PGNRYGI 478
Query: 789 APPPRIDDERLVGIAQKYNKTVPQVALRF 875
DD + + +KY KT Q+A RF
Sbjct: 479 T--NAWDDPIIQELVKKYGKTPAQIACRF 505
>UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9;
Endopterygota|Rep: ENSANGP00000031808 - Anopheles
gambiae str. PEST
Length = 316
Score = 186 bits (452), Expect = 9e-46
Identities = 99/262 (37%), Positives = 151/262 (57%), Gaps = 13/262 (4%)
Frame = +3
Query: 129 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 308
+VP +G +IP+ LGTW + P G+V Q D A++ GY HID A+ Y
Sbjct: 5 VVPNAIFKNGNSIPMFGLGTW--NSPPGQVAQAVKD-------AIDVGYRHIDCAHVYQN 55
Query: 309 EDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 485
E +VG + K +EG+ KRE +F+T+KLWN++H + V A + +L+NL L+Y+DLYLIH
Sbjct: 56 EHEVGEGIAAKIAEGVVKREDLFVTSKLWNTFHRPDLVEGACKTTLQNLKLDYLDLYLIH 115
Query: 486 WPIAMFENDTLL-----------DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI 632
WP+ E L + D++DTW M GL ++IG+SNFN +Q+QR+
Sbjct: 116 WPVGYQEGTELFPMGPDGKTFLFSDADYVDTWPEMEKLVDAGLVRNIGVSNFNAKQVQRV 175
Query: 633 IDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDD 812
+D P+ QIE + L Q ++ FC E I+V AY+P GS P++ A P + D
Sbjct: 176 LDVARIPPATNQIECHPYLHQSKITTFCAEKGIIVTAYSPLGS--PARPWVKADDPVLMD 233
Query: 813 ERLVG-IAQKYNKTVPQVALRF 875
+ VG +A+K+ K+ Q+ +R+
Sbjct: 234 DATVGQLAKKHGKSAAQILIRY 255
>UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep:
GA19341-PA - Drosophila pseudoobscura (Fruit fly)
Length = 315
Score = 186 bits (452), Expect = 9e-46
Identities = 107/259 (41%), Positives = 151/259 (58%), Gaps = 12/259 (4%)
Frame = +3
Query: 135 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 314
P+ LSSG N+P+V LGTW R +VV QAV A++ GY H D A+ YG E
Sbjct: 4 PSFLLSSGRNMPMVGLGTW---RSPPEVVA------QAVKDAIDIGYRHFDCAHIYGNEL 54
Query: 315 QVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 491
VG A+ +K EGL R+ +FIT+KLWN++H+ E V A SL NL ++Y+DLYL+HWP
Sbjct: 55 HVGVAIREKIQEGLVTRDELFITSKLWNTFHKPELVRAACETSLRNLGIDYLDLYLMHWP 114
Query: 492 IAMFENDTL-----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 638
+A D L +++D+LDTW+ M D GL +IG+SNFN++QI R++
Sbjct: 115 MAYKSGDNLYPTCPDTGKAVFEDIDYLDTWKAMEDLVDSGLVNAIGVSNFNEKQINRLLC 174
Query: 639 SGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
KP LQIE + L+Q L C +N I V AY+ GS +P + P + +
Sbjct: 175 LAKLKPVMLQIECHPYLRQKSLITLCYDNAIGVTAYSSLGSGHTPYEKPGS-YPLLQNPI 233
Query: 819 LVGIAQKYNKTVPQVALRF 875
+V +A+KY +T QV LR+
Sbjct: 234 IVSVAEKYGRTPAQVLLRY 252
>UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium
discoideum|Rep: Aldehyde reductase - Dictyostelium
discoideum AX4
Length = 297
Score = 185 bits (451), Expect = 1e-45
Identities = 107/257 (41%), Positives = 152/257 (59%), Gaps = 10/257 (3%)
Frame = +3
Query: 135 PTLQLSSGGNIPVVALGTWLGHRPK-GKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 311
P+ +LSSG IP+V GTW GK V+V AL+AGY HID A Y E
Sbjct: 3 PSFKLSSGHKIPLVGFGTWKAETTLVGKAVEV----------ALDAGYRHIDCAAVYLNE 52
Query: 312 DQVGRALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 485
+VG A TKKF+ +KRE +FIT+KLWN++H++E V PAL ++L +L L+Y+DLYL+H
Sbjct: 53 KEVGEAFTKKFTTEATVKREDVFITSKLWNTFHKKEHVRPALERTLSDLGLQYLDLYLVH 112
Query: 486 WPIAM--FEND-----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSG 644
WP+A ND + + V +TW M GL KSIG+SNFN + + ++
Sbjct: 113 WPVAFEYTSNDIQTSGSTQEFVSIRETWEEMEKLVDAGLVKSIGLSNFNVQGLMEVLSYA 172
Query: 645 LEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLV 824
KP+A Q+EL+ L QPEL KFC +++I + AY+P G+ +D+E +
Sbjct: 173 RIKPAANQVELHPFLSQPELKKFCDKHNIHLTAYSPLGN-----------GAFVDNEEVG 221
Query: 825 GIAQKYNKTVPQVALRF 875
IA+KYNKT+P V ++
Sbjct: 222 AIAKKYNKTIPNVLCKW 238
>UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep:
Aldo-keto reductase - Aedes aegypti (Yellowfever
mosquito)
Length = 324
Score = 185 bits (450), Expect = 2e-45
Identities = 110/265 (41%), Positives = 158/265 (59%), Gaps = 17/265 (6%)
Frame = +3
Query: 132 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 311
+PT++L++G +P + LGT + KG ++ +AV+ A++ G+ HIDTAY Y E
Sbjct: 6 IPTVKLNNGLEMPAIGLGTSMS---KG------DECCKAVMTAIDEGFRHIDTAYNYRNE 56
Query: 312 DQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 488
D VGRA+ K EG+ RE +F+TTKLWN++H + V A KSLE+L L+YVDL+LIH
Sbjct: 57 DVVGRAIRAKIEEGVVTREELFVTTKLWNTFHHPDHVPMAFGKSLEHLGLDYVDLFLIHM 116
Query: 489 PIAMF------ENDTLLD---NV-----DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQ 626
P E T LD NV D++DTW+ M + G SIG+SNFN EQ++
Sbjct: 117 PFGYEFNGWDPEKRTPLDDNGNVLCSDDDYVDTWKAMEKLLESGRVHSIGVSNFNSEQLE 176
Query: 627 RIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG--SLFPSKAQPXAPPP 800
RI+ + KP Q+E + + Q L +FC E DIVV A++PFG LF K P P
Sbjct: 177 RILANCRVKPVTNQVECSARINQKLLIEFCMERDIVVTAHSPFGRPHLF-EKNPKDKPKP 235
Query: 801 RIDDERLVGIAQKYNKTVPQVALRF 875
+D+ +V I +K++K+ QV LR+
Sbjct: 236 VLDEPEIVEIGKKFDKSSAQVVLRY 260
>UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 333
Score = 183 bits (446), Expect = 5e-45
Identities = 106/261 (40%), Positives = 150/261 (57%), Gaps = 15/261 (5%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++ L SG +P+V LGTW K K +V A+ A++AGY H D A YG E +
Sbjct: 4 SVTLPSGHAMPLVGLGTW-----KLKADEVAG----AIGAAVDAGYRHFDCALIYGNEKE 54
Query: 318 VGRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG AL + GLKRE +FITTK+WN++H +E V +SL +L L+Y+DLY++HWP+
Sbjct: 55 VGVALREAMQRLGLKREDVFITTKVWNTFHAKEDVAECFNRSLTDLQLDYIDLYIMHWPL 114
Query: 495 AMFEN-------------DTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII 635
F+N D + +V +L+TW M D K G KS+G+SNFN +Q+ ++
Sbjct: 115 G-FQNLGPTVMFPRTETGDIVYSDVHYLETWSAMEDLVKTGKCKSLGLSNFNSKQLDDVL 173
Query: 636 DSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRI-DD 812
PS LQ+E + L Q EL FCRE +VV AY+P G +A + P I DD
Sbjct: 174 QHSTVPPSVLQVESHPFLPQVELLNFCRERSVVVSAYSPLGC--GDRAWKLSGEPSIFDD 231
Query: 813 ERLVGIAQKYNKTVPQVALRF 875
L+ IAQ+ K++ QVA+RF
Sbjct: 232 PGLLKIAQRLRKSIAQVAIRF 252
>UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13;
n=11; Theria|Rep: Aldo-keto reductase family 1 member
C13 - Mus musculus (Mouse)
Length = 323
Score = 182 bits (442), Expect = 1e-44
Identities = 103/258 (39%), Positives = 152/258 (58%), Gaps = 13/258 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
++L+ G IP + GT+ K K V + E A + AL+ GY H+DTAY Y +E+++
Sbjct: 8 VKLNDGHLIPALGFGTY-----KPKEVPKSKSLEAACL-ALDVGYRHVDTAYAYQVEEEI 61
Query: 321 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
G+A+ K G+ KRE +FITTKLW + E V PAL KSL+ L L+YVDLY++H+P+
Sbjct: 62 GQAIQSKIKAGVVKREDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVP 121
Query: 498 MFEND----------TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 644
M D +LLD VDF DTW + + K GL KSIG+SNFN Q++RI++ G
Sbjct: 122 MKSGDNDFPVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERILNKPG 181
Query: 645 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERL 821
L+ KP Q+E +L L Q +L +C DIV++AY G+ + P ++D L
Sbjct: 182 LKYKPVCNQVECHLYLNQRKLLDYCESKDIVLVAYGALGTQRYKEWVDQNSPVLLNDPVL 241
Query: 822 VGIAQKYNKTVPQVALRF 875
+A+K ++ +ALR+
Sbjct: 242 CDVAKKNKRSPALIALRY 259
>UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA -
Drosophila melanogaster (Fruit fly)
Length = 322
Score = 181 bits (441), Expect = 2e-44
Identities = 103/260 (39%), Positives = 150/260 (57%), Gaps = 13/260 (5%)
Frame = +3
Query: 135 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 314
P LS+G N+P++ LGTW R +VV QAV A++ GY H D A+ YG E
Sbjct: 4 PNFLLSNGKNMPMLGLGTW---RSPPEVVT------QAVKDAIDIGYRHFDCAHIYGNEA 54
Query: 315 QVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 491
QVG AL +K EG+ R+ +FIT+KLWN++H+ + V PA S+ NL ++Y++LYL+HWP
Sbjct: 55 QVGAALREKMDEGVVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWP 114
Query: 492 IAMFE------------NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII 635
+A N +++D++DTWR M + GL ++IG+SNFN++Q+ R++
Sbjct: 115 MAYKSGSDNLYPTCPDTNKAAFEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLL 174
Query: 636 DSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDE 815
KP LQIE + L Q L C +N I V AY+ GS +P A P +
Sbjct: 175 SVAKLKPVVLQIECHPYLSQKPLITLCYDNAIAVTAYSCLGSGHTPYEKPGA-YPLLQHP 233
Query: 816 RLVGIAQKYNKTVPQVALRF 875
++ IA+KY +T QV LRF
Sbjct: 234 TILAIAEKYERTAAQVLLRF 253
>UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep:
Aldose reductase - Mus musculus (Mouse)
Length = 316
Score = 179 bits (436), Expect = 8e-44
Identities = 105/258 (40%), Positives = 150/258 (58%), Gaps = 13/258 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
L+L++G +P + LGTW P G+V + AV A++ GY HID A Y E +V
Sbjct: 5 LELNNGTKMPTLGLGTWKS--PPGQVTE-------AVKVAIDLGYRHIDCAQVYQNEKEV 55
Query: 321 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
G AL +K E + KR+ +FI +KLW ++H++ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 56 GVALQEKLKEQVVKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTG 115
Query: 498 M----------FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 644
+ + + DF+DTW M GL K+IG+SNFN QI+RI++ G
Sbjct: 116 FKPGPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPG 175
Query: 645 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERL 821
L+ KP+ QIE + L Q +L ++C IVV AY+P GS A+P P ++D R+
Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIEYCHSKGIVVTAYSPLGSPDRPWAKP-EDPSLLEDPRI 234
Query: 822 VGIAQKYNKTVPQVALRF 875
IA KYNKT QV +RF
Sbjct: 235 KAIAAKYNKTTAQVLIRF 252
>UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase;
n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid
dehydrogenase - Xenopus tropicalis (Western clawed frog)
(Silurana tropicalis)
Length = 324
Score = 179 bits (435), Expect = 1e-43
Identities = 98/259 (37%), Positives = 154/259 (59%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ + PK E+ A++ GY HID A+ YG E++
Sbjct: 9 VELNDGHKMPVIGFGTYAPPKFPKSLA-------EEGTKVAIDVGYRHIDCAFLYGNEEE 61
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VGRA+ K ++G +KRE +F T KLW++ H E+V PAL KSL++L L+Y+DL++IH P+
Sbjct: 62 VGRAIRAKIADGTVKREDVFYTGKLWSTSHTPERVRPALEKSLKDLQLDYMDLFIIHMPM 121
Query: 495 AMFENDTLL----------DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID-S 641
D L N D DTW+ + K GL +SIG+SNFN +Q++ I++
Sbjct: 122 EFKPGDDLFPADENGKFIYHNTDLRDTWKALEKCKDAGLVRSIGVSNFNHKQLELILNMP 181
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E ++ L Q +L +FC+ DIV++ Y+ GS + + P ++D
Sbjct: 182 GLKYKPVCNQVECHVYLNQSKLLEFCKSKDIVLVGYSVLGSSRDERWIEASTPVLLEDPA 241
Query: 819 LVGIAQKYNKTVPQVALRF 875
L IA+K+N+T QVA+R+
Sbjct: 242 LTEIAKKHNRTPAQVAMRY 260
>UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p -
Drosophila melanogaster (Fruit fly)
Length = 311
Score = 178 bits (434), Expect = 1e-43
Identities = 100/257 (38%), Positives = 151/257 (58%), Gaps = 8/257 (3%)
Frame = +3
Query: 129 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 308
+ PT++L++G +P + LGTW +D + +AL+ GY H+DTA+ Y
Sbjct: 4 LAPTIRLNNGREMPTLGLGTWKSFE---------SDAYHSTRHALDVGYRHLDTAFVYEN 54
Query: 309 EDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 485
E +VG+A+++K +EG+ RE +F+TTKL +H+ V A R SL NL LEYVDLYL+H
Sbjct: 55 EAEVGQAISEKIAEGVVTREEVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMH 114
Query: 486 WPIAM-FEND-----TL-LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSG 644
P+ F ND TL L +VD+LDTWR M LGLT+SIG+SNFN Q +R++ +
Sbjct: 115 MPVGQKFHNDSNVHGTLELTDVDYLDTWREMEKLVDLGLTRSIGLSNFNAAQTERVLANC 174
Query: 645 LEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLV 824
+P Q+E + QQ +L + + + +V+ AY P P++ PP + DE
Sbjct: 175 RIRPVVNQVECHPGFQQRQLREHAKRHGLVICAYCPLARPQPARQW----PPFLYDEHAQ 230
Query: 825 GIAQKYNKTVPQVALRF 875
+A+KY +T Q+ LR+
Sbjct: 231 NLAKKYGRTTAQICLRY 247
>UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep:
Aldose reductase - Homo sapiens (Human)
Length = 316
Score = 176 bits (429), Expect = 5e-43
Identities = 106/258 (41%), Positives = 153/258 (59%), Gaps = 13/258 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 321 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
G A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 498 ------MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 644
F D + + + LDTW M + GL K+IGISNFN Q++ I++ G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175
Query: 645 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERL 821
L+ KP+ QIE + L Q +L ++C+ IVV AY+P GS A+P P ++D R+
Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKP-EDPSLLEDPRI 234
Query: 822 VGIAQKYNKTVPQVALRF 875
IA K+NKT QV +RF
Sbjct: 235 KAIAAKHNKTTAQVLIRF 252
>UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18;
n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member
C18 - Mus musculus (Mouse)
Length = 323
Score = 176 bits (428), Expect = 7e-43
Identities = 97/261 (37%), Positives = 151/261 (57%), Gaps = 13/261 (4%)
Frame = +3
Query: 132 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 311
+ ++L+ G +IPV+ GT+ + + ++ A++ G+ HID ++ Y E
Sbjct: 5 IQKIELNDGHSIPVLGFGTYATEE------HLKKKSMESTKIAIDVGFCHIDCSHLYQNE 58
Query: 312 DQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 488
+++G+A+ K +G +KRE IF T+KLW++ H E V P+L SL LNL+YVDLYLIH+
Sbjct: 59 EEIGQAILSKIEDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHF 118
Query: 489 PIAMFENDTLL----------DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 638
P+++ + LL D VD DTW M K GL KSIG+SNFN+ Q++ I++
Sbjct: 119 PVSLKPGNELLPKDEHGNLIFDTVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILN 178
Query: 639 S-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDD 812
GL+ KP Q+E +L L Q +L +C+ NDIV++AY G+ P +DD
Sbjct: 179 KPGLKYKPVCNQVECHLYLNQSKLLAYCKMNDIVLVAYGALGTQRYKYCINEDTPVLLDD 238
Query: 813 ERLVGIAQKYNKTVPQVALRF 875
L +A+KY +T +ALR+
Sbjct: 239 PVLCAMAKKYKRTPALIALRY 259
>UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus
tropicalis|Rep: LOC594893 protein - Xenopus tropicalis
(Western clawed frog) (Silurana tropicalis)
Length = 345
Score = 174 bits (424), Expect = 2e-42
Identities = 107/274 (39%), Positives = 157/274 (57%), Gaps = 28/274 (10%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWL------------GH---RPKGKVVQVTNDTEQAVIYALEAG 272
++QL G +PVVA GT+ GH G +D A AL+ G
Sbjct: 8 SIQLHDGRWMPVVAFGTFYPFTFPGDSQANPGHCAGTKHGTEKSFIDDVRVATKMALDLG 67
Query: 273 YTHIDTAYKYGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLEN 449
Y H+D A+ Y E VG+A +KF++G LKRE +F T+KLWN++H+ V PAL K+L
Sbjct: 68 YRHVDGAFLYSSETGVGQAFREKFADGTLKREDLFYTSKLWNTFHQPHLVRPALEKTLSF 127
Query: 450 LNLEYVDLYLIHWPIA------MF---ENDT-LLDNVDFLDTWRGMIDAKKLGLTKSIGI 599
L ++YVDLYLIH P++ +F E+ T D D L TW+ + + + GL KSIG+
Sbjct: 128 LQMDYVDLYLIHMPMSFKPAEELFPKNEDGTCAFDQPDLLQTWQALEECRDAGLVKSIGV 187
Query: 600 SNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPS 773
SNFN+ Q++ I++ GL+ KP QIE + L Q ++ +FC+ DIVV+AY GS
Sbjct: 188 SNFNRRQLEMILNKPGLKYKPVCNQIECHPYLNQKQMLEFCKSKDIVVVAYGVLGSPGAG 247
Query: 774 KAQPXAPPPRIDDERLVGIAQKYNKTVPQVALRF 875
K + P ++D L+ I QKY+K+ QV++R+
Sbjct: 248 KWVDQSCPILLEDPVLISIGQKYSKSPAQVSMRY 281
>UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5;
Bacteroidetes|Rep: Aldehyde reductase - Croceibacter
atlanticus HTCC2559
Length = 316
Score = 174 bits (423), Expect = 3e-42
Identities = 96/248 (38%), Positives = 145/248 (58%), Gaps = 12/248 (4%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
TL+ G +IP + LGTW D ++AV ALE GY HID A Y ED
Sbjct: 3 TLKFRDGDSIPSIGLGTWKSD---------PEDVKKAVKIALENGYKHIDCAAAYDNEDA 53
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A + F G +KRE IF+T+KLWN+ H++E VIPAL+K+L++LNL+Y+DLYL+HWP+
Sbjct: 54 VGEAFKESFESGNVKREDIFVTSKLWNNAHKKEDVIPALKKTLKDLNLDYLDLYLMHWPV 113
Query: 495 AM---------FENDTL-LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSG 644
A + D L L+ +T MI+AKK GL K +G+SNF++E+++ +
Sbjct: 114 AFKPSVNGFPEKDEDYLSLEEAPLHETLNAMIEAKKQGLIKHVGVSNFSKEKLESLKGKV 173
Query: 645 LEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRI-DDERL 821
E P Q+EL+ L Q +L+ +C + I++ Y+P GS S+ P + +D+ +
Sbjct: 174 EEMPEMNQVELHPYLPQNDLYSYCSKEGILLTGYSPLGSGDRSEGMKADDEPSLFEDDTI 233
Query: 822 VGIAQKYN 845
+A++ N
Sbjct: 234 KKVAERNN 241
>UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA15457-PA - Nasonia vitripennis
Length = 388
Score = 173 bits (420), Expect = 7e-42
Identities = 106/262 (40%), Positives = 150/262 (57%), Gaps = 15/262 (5%)
Frame = +3
Query: 132 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 311
V L+LSSG IP V LGT +++ ++ + A+ ALE GY HIDTA+ Y E
Sbjct: 23 VEKLKLSSGHEIPAVGLGT--------STIKL-DEMDNAISSALENGYRHIDTAFSYDNE 73
Query: 312 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 491
+G+ L K F +G KRE IFIT+KL + + + V L++SL++L L+YVD+YLIH P
Sbjct: 74 AAIGKILKKWFDKGGKREDIFITSKLPSQGNRPQSVETYLKRSLKDLGLDYVDMYLIHTP 133
Query: 492 IAMFENDT-----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 638
A+ E + L D+VD W+ M K G KSIG+SNFNQ Q+ I +
Sbjct: 134 FAVKEGENLSSKQDKDGNDLFDDVDHKALWKAMERQVKEGRAKSIGLSNFNQSQVLNIYN 193
Query: 639 SGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS----LFPSKAQPXAPPPRI 806
+ KPS LQ+E + LQQ +L KFC+E++IV+ AY P GS L + P P +
Sbjct: 194 NAEIKPSNLQVETHAYLQQKQLRKFCKEHNIVMTAYAPLGSHNARLNLHRGTPKELPALV 253
Query: 807 DDERLVGIAQKYNKTVPQVALR 872
+ + +A KYNK+ Q+ LR
Sbjct: 254 ELPLIKSLAAKYNKSPGQILLR 275
>UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 316
Score = 172 bits (419), Expect = 9e-42
Identities = 100/260 (38%), Positives = 150/260 (57%), Gaps = 11/260 (4%)
Frame = +3
Query: 129 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 308
+V +L+L+SG +IP + LGTW +P G+V A+ A+ AGY HID A+ Y
Sbjct: 1 MVQSLKLNSGYSIPAIGLGTWQS-KP-GEVAA-------AIKTAVAAGYRHIDCAHVYQN 51
Query: 309 EDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 485
+ +VG AL + EG +KRE +FIT+K+WN++H + + L +L L YVDL LIH
Sbjct: 52 QKEVGEALKEILDEGKVKREELFITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIH 111
Query: 486 WPIAMFENDTLL----------DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII 635
WP E L +VD+L+TW+ A+K G +SIG+SNF QIQR+
Sbjct: 112 WPQGYAEGAELFPAGENGKMRYSDVDYLETWKAFEAAQKAGKCRSIGLSNFTHSQIQRVW 171
Query: 636 DSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDE 815
D+ KP+ LQ+EL+ Q +L +FC+E IVV+ Y+P G+ + + P + +E
Sbjct: 172 DAAEVKPACLQVELHPYFTQVKLREFCKEKGIVVVGYSPLGNPGSAFFRKDGDPNVLTNE 231
Query: 816 RLVGIAQKYNKTVPQVALRF 875
+ GIA+ + KT Q+ LR+
Sbjct: 232 VVAGIAKAHGKTPAQIILRW 251
>UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1;
Orconectes limosus|Rep: Aldoketoreductase-like protein -
Orconectes limosus (Spinycheek crayfish)
Length = 336
Score = 171 bits (417), Expect = 2e-41
Identities = 104/262 (39%), Positives = 149/262 (56%), Gaps = 14/262 (5%)
Frame = +3
Query: 132 VPTLQLSSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 308
+PT+ L+SG +IPV+ LGT LG K VT E A LE GY H D+A YG
Sbjct: 11 IPTILLNSGSHIPVMGLGTGSLGRNGKMSEEAVTAVLETA----LECGYRHFDSAAYYGN 66
Query: 309 EDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 485
E +G+ L + SEG +KRE +FITTKL + + V L+KSL+NL L YVDLYL+H
Sbjct: 67 EAIIGQVLRRWISEGKVKREELFITTKLPTRGNREKDVARFLQKSLDNLRLPYVDLYLVH 126
Query: 486 WPIAMFEND---------TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 638
+P + + D T+ D WR M G TK+IG+SNFN +Q+QRII
Sbjct: 127 YPCGILDTDRERLSADEVTVDPTTDIHAIWRAMEAQLAAGKTKNIGLSNFNADQVQRIIK 186
Query: 639 SGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS---LFPSKAQPXAPPPRID 809
+P+ LQ+E+++ +QQ L FC ++DIVV A+ P G L ++P ++
Sbjct: 187 GCQVRPAVLQVEVHVYMQQGALRAFCAQHDIVVCAFCPLGGPFRLIRKASRPGEVKLLLE 246
Query: 810 DERLVGIAQKYNKTVPQVALRF 875
D +++ +A ++KT QV LR+
Sbjct: 247 DPQVLDVATAHHKTPAQVLLRY 268
>UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC
1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase);
n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid
4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid
5-beta-reductase) - Homo sapiens (Human)
Length = 326
Score = 168 bits (408), Expect = 2e-40
Identities = 99/258 (38%), Positives = 147/258 (56%), Gaps = 13/258 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
+ LS G +IP++ LGT+ + K T+ V A++ GY HID AY Y E +V
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATS-----VKVAIDTGYRHIDGAYIYQNEHEV 64
Query: 321 GRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
G A+ +K +EG ++RE IF KLW + H E V P L ++L L L+YVDLY+I P+A
Sbjct: 65 GEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMA 124
Query: 498 MFENDTLL---DNVDFL-------DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 644
D + +N +L TW M K GL KS+G+SNFN+ Q++ I++ G
Sbjct: 125 FKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPG 184
Query: 645 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERL 821
L+ KP + Q+E + QP+L KFC+++DIV+ AY+P G+ + PP + D L
Sbjct: 185 LKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALL 244
Query: 822 VGIAQKYNKTVPQVALRF 875
+ ++YNKT Q+ LRF
Sbjct: 245 NSLGKRYNKTAAQIVLRF 262
>UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30;
Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus
(Mouse)
Length = 316
Score = 167 bits (406), Expect = 3e-40
Identities = 98/256 (38%), Positives = 143/256 (55%), Gaps = 13/256 (5%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 326
L +G +P+V LGTW P KV +AV A++AGY HID AY Y E +VG
Sbjct: 7 LLTGAKMPIVGLGTWKS--PPAKV-------REAVKVAIDAGYRHIDCAYVYQNESEVGE 57
Query: 327 ALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 503
A+ +K E +KRE +FI +KLW+++ E+ V A + +L +L L+Y+DLYLIHWP
Sbjct: 58 AIQEKIQEKAVKREDLFIVSKLWSTFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWPQGFQ 117
Query: 504 ENDTLLDNVD----------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE 650
+ L D FLD W M + GL K++G+SNFN QI+R+++ GL+
Sbjct: 118 SGNVFLPTDDKGSILSSKYTFLDAWEAMEELVDQGLVKALGVSNFNHFQIERLLNKPGLK 177
Query: 651 -KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVG 827
KP Q+E + L Q +L ++C I + AY+P GS A+P P ++ ++
Sbjct: 178 HKPVTNQVECHPYLTQEKLTQYCHSKGITITAYSPLGSPDRPSAKP-EDPLLLEIPKIKE 236
Query: 828 IAQKYNKTVPQVALRF 875
IA K+ KT QV +RF
Sbjct: 237 IAAKHKKTAAQVLIRF 252
>UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone
synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent
6'-deoxychalcone synthase - Glycine max (Soybean)
Length = 315
Score = 166 bits (404), Expect = 6e-40
Identities = 89/223 (39%), Positives = 137/223 (61%), Gaps = 9/223 (4%)
Frame = +3
Query: 234 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL-KRESIFITTKLWNSYHER 410
DT++A+I A++ GY H DTA YG E +G AL + GL R+ +F+T+KLW + +
Sbjct: 37 DTKEAIIEAVKQGYRHFDTAAAYGSEQALGEALKEAIHLGLVSRQDLFVTSKLWVTENHP 96
Query: 411 EQVIPALRKSLENLNLEYVDLYLIHWPIAM--------FENDTLLDNVDFLDTWRGMIDA 566
V+PALRKSL+ L LEY+DLYLIHWP++ E + LL D W M +
Sbjct: 97 HLVLPALRKSLKTLQLEYLDLYLIHWPLSSQPGKFSFPIEVEDLLP-FDVKGVWESMEEC 155
Query: 567 KKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAY 746
+KLGLTK+IG+SNF+ +++Q ++ +P Q+E+NL QQ +L +FC+EN I+V A+
Sbjct: 156 QKLGLTKAIGVSNFSVKKLQNLLSVATIRPVVDQVEMNLAWQQKKLREFCKENGIIVTAF 215
Query: 747 TPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQVALRF 875
+P K P ++++ L IA+ + K++ QV+LR+
Sbjct: 216 SPL-----RKGASRGPNEVMENDVLKEIAEAHGKSIAQVSLRW 253
>UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae
str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae
str. PEST
Length = 319
Score = 165 bits (402), Expect = 1e-39
Identities = 97/264 (36%), Positives = 151/264 (57%), Gaps = 16/264 (6%)
Frame = +3
Query: 132 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 311
VPT++ S+G IPV+ GT+L KG+ V++ A++ GY HIDTA+ Y E
Sbjct: 5 VPTVRFSNGYEIPVLGYGTYLAQ--KGQCVELVKK-------AIDLGYRHIDTAFLYENE 55
Query: 312 DQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 488
++G+A+ K +EG ++RE +F+TTKLWN++H+ + V A R+S + L++ Y+DL+L+H
Sbjct: 56 VEIGQAIRDKIAEGVIRREDVFVTTKLWNTFHDPQHVEEAFRRSFDMLDIGYIDLFLMHS 115
Query: 489 PIAM----FE----------NDTLLDNVDFLDTWRGMIDAKKL-GLTKSIGISNFNQEQI 623
P+ + +E + L +VD+++TW+ M G +SIG+SNFN EQI
Sbjct: 116 PMGVQFSGYEYADMQPKDAAGNMLFSDVDYVETWKAMEKLVTAGGRVRSIGLSNFNSEQI 175
Query: 624 QRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPR 803
+RI+ KP Q+E N Q +L FC+ I V AY P G P +
Sbjct: 176 ERILQIATVKPVNNQVEANPGYDQRKLIAFCQARGITVTAYGPMGR--PHRT-TNGNRNA 232
Query: 804 IDDERLVGIAQKYNKTVPQVALRF 875
+DD +++ I +KY KT QV LR+
Sbjct: 233 LDDPKVLEIGRKYGKTGGQVILRY 256
>UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44;
Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo
sapiens (Human)
Length = 325
Score = 165 bits (401), Expect = 1e-39
Identities = 94/255 (36%), Positives = 141/255 (55%), Gaps = 12/255 (4%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 326
L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G
Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58
Query: 327 ALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 500
AL + G + RE +F+T+KLWN+ H E V PALRK+L +L LEY+DLYL+HWP A
Sbjct: 59 ALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118
Query: 501 FENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 650
D D+ + +TW+ + GL +++G+SNFN QI I+
Sbjct: 119 ERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV 178
Query: 651 KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGI 830
+P+ LQ+E + L Q EL C+ + V AY+P GS + P P +++ ++ +
Sbjct: 179 RPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPD-EPVLLEEPVVLAL 237
Query: 831 AQKYNKTVPQVALRF 875
A+KY ++ Q+ LR+
Sbjct: 238 AEKYGRSPAQILLRW 252
>UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13;
Pezizomycotina|Rep: Aldehyde reductase - Coccidioides
posadasii
Length = 314
Score = 165 bits (400), Expect = 2e-39
Identities = 96/254 (37%), Positives = 143/254 (56%), Gaps = 10/254 (3%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
T +L++G +IP + GTW Q N E AV+ AL AGY HIDTA YG E
Sbjct: 7 TFRLNTGEDIPAIGFGTW----------QDENAQEDAVLTALSAGYRHIDTAAVYGTEKA 56
Query: 318 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
+GRAL + L R+ +FIT+KLWN+ H E V A+ +SL+NL ++Y+DLYL+HWP A
Sbjct: 57 IGRALARS---RLSRDELFITSKLWNNKHRPEDVEQAIDQSLKNLEIDYLDLYLMHWPAA 113
Query: 498 MFENDTLLD----------NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 647
D + ++D++DT++ M K G TK+IGISNF++ +++R+++S
Sbjct: 114 FAPGDDMFPKDSQGNSKTVDIDYVDTYKAMEKLVKSGKTKAIGISNFSKGEMERLLESCS 173
Query: 648 EKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVG 827
P+ +Q+EL+ LQQ + ++ + I V Y+ G+ + I+D L
Sbjct: 174 IVPAVMQMELHPWLQQNDFVEWLKSKGIHVTQYSSLGNQNEVYSGRERYGRLIEDPALAA 233
Query: 828 IAQKYNKTVPQVAL 869
I KY KT QVAL
Sbjct: 234 IGTKYGKTGAQVAL 247
>UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 303
Score = 163 bits (396), Expect = 5e-39
Identities = 97/253 (38%), Positives = 147/253 (58%), Gaps = 8/253 (3%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
L L++G +IP + LGT+ K+ +D A+ A+E GY IDTA+ Y E V
Sbjct: 2 LALNNGHSIPPIGLGTY-------KITG--SDGVAAIKSAVEFGYRLIDTAFVYNNEQVV 52
Query: 321 GRALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
G+AL + FS+G + RE +FI +KL ++H E V R SLE L L+YVDLYL+H P+
Sbjct: 53 GQALREIFSQGNDINREDVFIVSKLGPTFHRPEAVEKGCRLSLERLGLDYVDLYLMHTPV 112
Query: 495 AMFE----NDT--LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKP 656
A + ND + D V L+TW+ + + ++ GL +SIG+SNFN+EQ+ I+ G +P
Sbjct: 113 AARDSGDGNDRSEIDDEVTPLETWKALEECQRKGLVRSIGVSNFNEEQLMEIVTHGSIRP 172
Query: 657 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQ 836
Q+E ++ Q +L KFC I++MAY+P G K +P +D L +A+
Sbjct: 173 VVNQVECSIGFHQVKLRKFCNREGILIMAYSPLG-----KPKPGKKHVFLDSSDLNKMAE 227
Query: 837 KYNKTVPQVALRF 875
KY ++ Q++LRF
Sbjct: 228 KYGRSPAQISLRF 240
>UniRef50_Q41399 Cluster: Chalcone reductase; n=4;
eudicotyledons|Rep: Chalcone reductase - Sesbania
rostrata
Length = 322
Score = 162 bits (394), Expect = 9e-39
Identities = 89/262 (33%), Positives = 148/262 (56%), Gaps = 10/262 (3%)
Frame = +3
Query: 120 ADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYK 299
A+ +P + L+SG +PV+ +GT + RP V+ + A++ GY H D+A
Sbjct: 2 AEKKIPEVLLNSGHKMPVIGMGTSVESRPSNDVLA------SIFVDAIQVGYRHFDSASV 55
Query: 300 YGIEDQVGRALTKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDL 473
YG E+ +G A++K +GL R+ +FIT+K WN+ + ++PAL+ +L+ L +EYVDL
Sbjct: 56 YGTEEAIGMAVSKAIEQGLIKSRDEVFITSKPWNTDAHHDLIVPALKTTLKKLGMEYVDL 115
Query: 474 YLIHWPIAM---FENDTLLDNVDFLD-----TWRGMIDAKKLGLTKSIGISNFNQEQIQR 629
YLIHWP+ + EN + D L TW+ M + +LGL KSIGI N+ +++ +
Sbjct: 116 YLIHWPVRLRHDLENPVIFSKEDLLPFDIEGTWKAMEECYRLGLAKSIGICNYGTKKLTK 175
Query: 630 IIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRID 809
+++ P+ Q+E+N + QQ L +FC++ I V A++P G+ ++
Sbjct: 176 LLEIATIPPAVNQVEMNPSWQQGNLREFCKQKGIHVSAWSPLGAYKIFWGSGAV----ME 231
Query: 810 DERLVGIAQKYNKTVPQVALRF 875
++ L IA KT+ QVALR+
Sbjct: 232 NQILQDIATAKGKTIAQVALRW 253
>UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep:
GCY protein - Lodderomyces elongisporus (Yeast)
(Saccharomyces elongisporus)
Length = 295
Score = 161 bits (391), Expect = 2e-38
Identities = 97/248 (39%), Positives = 143/248 (57%), Gaps = 4/248 (1%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
T L++G IP + LGTWL +A + AL+ GY HIDTA YG EDQ
Sbjct: 11 TYTLNNGLKIPAIGLGTWLADEEDAAY--------KATLTALKNGYKHIDTAAAYGNEDQ 62
Query: 318 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
VGRA+ G+ R+ IF+TTKLWN H+ + AL +SL+ L LEYVDLYLIHWP++
Sbjct: 63 VGRAIA---DSGVSRDEIFVTTKLWNDQHKDPE--GALDESLKKLGLEYVDLYLIHWPLS 117
Query: 498 MF-ENDTLLDNVDFLDTWRGMIDAKKLG-LTKSIGISNFNQEQIQRIIDS-GLE-KPSAL 665
+ + + D+ DF+DTWR + K G K+IG+SNFN++++ ++++S G+ P
Sbjct: 118 VDPKTEKPYDDYDFVDTWRNLQKIYKEGKKVKAIGVSNFNKKKLDKLLNSEGVNVVPVIN 177
Query: 666 QIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYN 845
QIE + L QP+LF + + DI + AY+P G A + ++ + IA+K+N
Sbjct: 178 QIEAHPLLTQPDLFDYLKSKDIYITAYSPLG---------HADASTLKNKVVTDIAKKHN 228
Query: 846 KTVPQVAL 869
QV +
Sbjct: 229 ANAGQVLI 236
>UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2;
Ascomycota|Rep: Aldo/keto reductase family proteins -
Aspergillus oryzae
Length = 323
Score = 159 bits (386), Expect = 9e-38
Identities = 101/252 (40%), Positives = 144/252 (57%), Gaps = 15/252 (5%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
T +L+SG NIP + LGTWL +P ++ E AV AL AGY HID A Y E++
Sbjct: 6 TFKLNSGYNIPAIGLGTWLS-KP--------HEVENAVEAALRAGYRHIDAAACYQNENE 56
Query: 318 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
VG K G+ R+ IFIT+KLWN++H E V A+ K+L++L +Y+DLYLIHWP+A
Sbjct: 57 VGNGWKKS---GVPRDQIFITSKLWNTHHHPEHVEEAVNKTLKDLQTDYLDLYLIHWPVA 113
Query: 498 M-FENDTL-----------LDNVDFLDTWRG---MIDAKKLGLTKSIGISNFNQEQIQRI 632
N+TL L NV DTW +++AKK+ +SIGISNF Q++I +
Sbjct: 114 FEHTNETLTPIDPVTKRFRLANVPIADTWAALEKLVEAKKI---RSIGISNFTQDKIDDL 170
Query: 633 IDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDD 812
+ + P+ QIE + LQQP L K+ +E +I+ +AY+P G+ + P +DD
Sbjct: 171 LKTAKIPPAVNQIEAHPYLQQPGLHKYLKEKNILSVAYSPLGNNIYN------APRVVDD 224
Query: 813 ERLVGIAQKYNK 848
+ IA K K
Sbjct: 225 PDVKAIADKLGK 236
>UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep:
Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea)
Length = 321
Score = 159 bits (385), Expect = 1e-37
Identities = 97/258 (37%), Positives = 147/258 (56%), Gaps = 10/258 (3%)
Frame = +3
Query: 132 VPTLQLSSGGN-IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 308
+P + LSSGG +PV+ LGT + V+ +AV AL+ GY H DTA Y
Sbjct: 5 IPEVPLSSGGRKMPVLGLGTAADPPVDPETVR------KAVTEALKLGYRHFDTAALYNS 58
Query: 309 EDQVGRALTKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 482
E +G A+ + EGL R+ +FIT+KLW S RE V PAL+K+L+NL LEY+D+YLI
Sbjct: 59 EQPLGDAIAEALGEGLIKSRDELFITSKLWCSDAHRENVEPALQKTLKNLKLEYIDMYLI 118
Query: 483 HWPIAM----FENDTLLDN---VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS 641
HWP++ +E ++ +D+ W M + +KLGLTK+IG+SNF+ +++ ++ +
Sbjct: 119 HWPVSSKPGNYEYPIKKEDFLQMDYKSVWEAMEECQKLGLTKAIGVSNFSCKKLSDVLAN 178
Query: 642 GLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERL 821
P+ Q+E+N QQ +L +FC+ N I+V+AY G++ + E L
Sbjct: 179 AKVPPAVNQVEVNPCWQQKQLTEFCKSNGILVVAYAALGAVGTFYGTNRV----MGSEVL 234
Query: 822 VGIAQKYNKTVPQVALRF 875
IA+ TV QV LR+
Sbjct: 235 NEIARIRGNTVAQVCLRW 252
>UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 320
Score = 158 bits (383), Expect = 2e-37
Identities = 103/258 (39%), Positives = 145/258 (56%), Gaps = 11/258 (4%)
Frame = +3
Query: 132 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 311
VP LS+G +P + LGTW +GK V + N A+ AGY HIDTA Y E
Sbjct: 5 VPIFTLSNGVLMPSIGLGTWQMTGEEGKTV-IRN--------AVLAGYRHIDTATLYQNE 55
Query: 312 DQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 488
Q+G AL + F+EG LKRE IFITTK + + V ALR SL+ L L+YVDLYL H
Sbjct: 56 HQIGDALAELFAEGILKREDIFITTKAFCHEVAPDVVEEALRNSLKRLRLDYVDLYLAHI 115
Query: 489 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 668
P + ++ + +V D WRG LGLTK+IG+SNFN+ QI RI++ A Q
Sbjct: 116 PASTKDDGSFRSDVKVEDIWRGFEKVYGLGLTKAIGVSNFNESQIVRIMNIQKVPIHASQ 175
Query: 669 IELNLNLQQPELFKFCRENDIVVMAYTPFG-----SLFPSKAQPXAPPPR-----IDDER 818
+EL+L L Q + C++++I++ AY G S+ S +P + ++D+
Sbjct: 176 LELHLYLPQKAHRELCKKHNILITAYATLGSPGRMSVVGSNGRPLFESTQNSENEMNDKH 235
Query: 819 LVGIAQKYNKTVPQVALR 872
+ +AQKY+KT Q+ LR
Sbjct: 236 VKALAQKYSKTPAQILLR 253
>UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:
Aldehyde reductase - Salinibacter ruber (strain DSM
13855)
Length = 321
Score = 157 bits (382), Expect = 3e-37
Identities = 93/257 (36%), Positives = 145/257 (56%), Gaps = 11/257 (4%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++ +G +P++ LGTW P G+V + AV ALEAGY H+D A Y E +
Sbjct: 3 SISFENGDEMPMIGLGTWKS--PPGEVYE-------AVTTALEAGYRHVDCAPIYKNETE 53
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG AL+ F G ++R+ +++T+KLWN+ H + V PAL ++L +L L+ +DLYLIHWP+
Sbjct: 54 VGAALSDSFDAGGIRRDDVWVTSKLWNNAHHPDDVRPALEQTLSDLRLDALDLYLIHWPV 113
Query: 495 AMF-ENDTLLDNVDFL--------DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 647
A+ E D DF+ +TW M KK GL + IG+SNF+ +Q I+D+G
Sbjct: 114 ALQPEVDFPESPDDFVSPEAVPLTETWAAMEALKKDGLVRHIGVSNFSVPNLQMILDAGE 173
Query: 648 EKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS-LFPSKAQPXAPPPRIDDERLV 824
+P Q+E++ L QPEL F ++I + AY+P GS P + P + + +
Sbjct: 174 VRPEMNQVEMHPYLPQPELVSFAEAHNIPITAYSPLGSGDRPDAMKADDEPTLMANPTIN 233
Query: 825 GIAQKYNKTVPQVALRF 875
IA ++ + QV L++
Sbjct: 234 DIADRHGVSPAQVLLQW 250
>UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=9; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 308
Score = 156 bits (379), Expect = 6e-37
Identities = 99/254 (38%), Positives = 146/254 (57%), Gaps = 17/254 (6%)
Frame = +3
Query: 165 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYAL-EAGYTHIDTAYKYGIEDQVGRALTKK 341
IP + LGTW R + D A+ YA+ EAGY HID A Y ED VG+AL +
Sbjct: 4 IPTIGLGTWKSPR--------SEDLVNAITYAIKEAGYVHIDCALCYENEDIVGQALQQC 55
Query: 342 FSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN---- 509
+ G+KRE+I+IT+KLWN++H E V A RK+L++L L+Y+DLYL+H+P A F+N
Sbjct: 56 WDSGIKRENIWITSKLWNTHHRLEIVEEACRKTLKDLRLDYLDLYLMHYPFA-FQNTGIG 114
Query: 510 ----------DTLLDN-VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE-K 653
+T+ D+ V +DTW+ M + GL K IG+SN+ Q++R+ S +
Sbjct: 115 GSLNPLDEKGNTIFDDGVSLIDTWKAMEKLVEKGLVKRIGVSNWTINQLERLKYSDAKTT 174
Query: 654 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIA 833
P Q+E NL +QQ L ++ + I+V Y+ G+ P A+P P + DE L IA
Sbjct: 175 PYTNQVEFNLYMQQGPLREYMHKEGIIVTGYSTLGT--PDWAKPDEPVV-LKDEELNKIA 231
Query: 834 QKYNKTVPQVALRF 875
+ K+V +V L+F
Sbjct: 232 AETGKSVGEVELKF 245
>UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9;
Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 316
Score = 156 bits (378), Expect = 8e-37
Identities = 98/255 (38%), Positives = 135/255 (52%), Gaps = 11/255 (4%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
+ +G +P + GTW + E+A+ ALEAGY HIDTA Y E +
Sbjct: 7 ITFENGTTMPALGFGTWRAS---------DEEVEKALNEALEAGYRHIDTAPVYLNEKTI 57
Query: 321 GRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
G+ L + G + R+ +FI TKL V L+ SL++L LEYVDLY +H P
Sbjct: 58 GKVLKEWMDAGKVTRDELFIVTKLPPHGTRASTVEKFLKNSLDDLQLEYVDLYHVHVPFT 117
Query: 498 MFEND----------TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 647
+ E D L D + W+ M + + GL ++IG+SNFNQ QIQRI+D+
Sbjct: 118 VPEVDGPFLVEDGLIVLETTTDHVALWKAMEEVYEAGLARNIGLSNFNQRQIQRILDNCQ 177
Query: 648 EKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVG 827
KP+ LQIE ++ LQQPEL KFC+ N I V AY+P GS K P +D+ +
Sbjct: 178 IKPANLQIENHIYLQQPELVKFCKANGITVTAYSPLGSKGIEKLLGREVPDLLDNPVVKD 237
Query: 828 IAQKYNKTVPQVALR 872
IA+K K+ QV LR
Sbjct: 238 IAEKLGKSPAQVLLR 252
>UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
CG2767-PA - Nasonia vitripennis
Length = 356
Score = 155 bits (376), Expect = 1e-36
Identities = 104/262 (39%), Positives = 142/262 (54%), Gaps = 17/262 (6%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
T++LSSG ++P++ LGTW P + E AV ALE+GY HIDTA+ YG E+
Sbjct: 27 TIKLSSGHDMPMIGLGTW--QMPPEAI-------EVAVTAALESGYRHIDTAFTYGNEEA 77
Query: 318 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
+G+ L K F +G KRE +FITTKL E V L+ SLE L LEYV++YLIH P A
Sbjct: 78 IGKTLKKWFDKGGKREDLFITTKLPPIGMRAEYVESYLKLSLEKLGLEYVNMYLIHKPFA 137
Query: 498 MF------------ENDTLLD-NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 638
+ +LD + D + WR M K G +SIG+SNFN+ Q+ + +
Sbjct: 138 FVKDKYKYEPALNPDGSVVLDTDTDHVAIWRAMEKQVKAGRVRSIGLSNFNKSQLLNVYE 197
Query: 639 SGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPS---KAQPXAPPPRID 809
KPS LQIEL QQ + + C E +I V A++ GS S K + P +
Sbjct: 198 HAEIKPSNLQIELQAYNQQRPMRELCAERNITVTAFSTLGSPGSSPDKKTRYIKSLPTLF 257
Query: 810 DERLV-GIAQKYNKTVPQVALR 872
D +V IA+ +N+T QV LR
Sbjct: 258 DHPIVKKIAEAHNRTSAQVLLR 279
>UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase
family; n=2; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 305
Score = 155 bits (376), Expect = 1e-36
Identities = 86/246 (34%), Positives = 143/246 (58%), Gaps = 3/246 (1%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 326
L++G IP + LGTW+ + +AV A++ GY HID A YG E +VG
Sbjct: 7 LNNGYKIPKLGLGTWMS---------ANGEVGKAVEIAIKNGYRHIDCAKAYGNEKEVGD 57
Query: 327 ALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 503
+ ++G +KRE +F+TTKLW++ +E V PA +SL+ L LEY+DLY+IH P+
Sbjct: 58 GIKSAIAKGYVKREELFVTTKLWSTDKHKEDVRPACLESLKKLQLEYLDLYIIHIPLTAD 117
Query: 504 EN--DTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 677
+ + + + +TWR M + GL KSIG+SNFN ++++ ++ +P+ Q E
Sbjct: 118 KKTGEFTEEIIPIEETWREMEKLVEEGLVKSIGVSNFNIKKLEELLAIAKIQPAVNQFEF 177
Query: 678 NLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVP 857
++ Q+P+L +FC++++I + Y P G+ S P AP ++E + IA+K+NK
Sbjct: 178 HIYYQRPKLHQFCKKHNIHITGYCPLGNPGISSGVP-AP---FENEVVKAIAKKHNKKAA 233
Query: 858 QVALRF 875
Q+ ++F
Sbjct: 234 QICIKF 239
>UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 345
Score = 155 bits (376), Expect = 1e-36
Identities = 95/256 (37%), Positives = 141/256 (55%), Gaps = 12/256 (4%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
T +L++G ++P V LGTW + ++ AVI AL+ GY HID A YG E +
Sbjct: 6 TFKLNTGYDMPAVGLGTWQSKK---------DEVRDAVIAALKCGYRHIDAAAVYGNEQE 56
Query: 318 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
VG + G+ RE IF+T+KLWN++H E V A+ KSL +L +Y+DLYLIHWP+A
Sbjct: 57 VGDGMRLS---GVPREEIFLTSKLWNTHHHPENVEEAVDKSLADLQTDYLDLYLIHWPVA 113
Query: 498 ----------MFENDTLLDNVD--FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS 641
+ E L+D VD DTW M + G +SIG+SNF +E+I+ ++ +
Sbjct: 114 FRYSTTTIQPVNEQTGLIDVVDVPIKDTWAAMEKLVEKGKVRSIGVSNFTREKIEELLKT 173
Query: 642 GLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERL 821
P+ QIE + LQQ +L ++ + IVV Y+P G+ + P +DD +
Sbjct: 174 AKITPAVNQIEAHPFLQQRDLLEWSTQKGIVVAGYSPLGNNIYN------IPRAVDDPLV 227
Query: 822 VGIAQKYNKTVPQVAL 869
+ A+K NKT QV +
Sbjct: 228 IETAKKLNKTPAQVLI 243
>UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon
cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon
cuniculi
Length = 301
Score = 154 bits (373), Expect = 3e-36
Identities = 100/261 (38%), Positives = 144/261 (55%), Gaps = 11/261 (4%)
Frame = +3
Query: 126 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYG 305
+I T +L++G IP V LGTW G + + E A+ AL GY HIDTA+ YG
Sbjct: 1 MICKTQKLNNGKEIPTVGLGTW-GMEDEAVL-------EGAIRNALSLGYRHIDTAFIYG 52
Query: 306 IEDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 482
E +G L K F EG+ +R+ +FIT+KLWN++H + LR+SL +L ++YVDLYLI
Sbjct: 53 NEKMIGNILKKLFDEGVVQRKDLFITSKLWNTFHGCPE--DGLRRSLNDLQMDYVDLYLI 110
Query: 483 HWPIAM-------FENDTLLDNV---DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI 632
HWP+ E+ NV D + W+ M LGL KSIGISNF + ++I
Sbjct: 111 HWPVTFDPAPDGTVESCGKKYNVGKFDAVGVWKKMEALVDLGLAKSIGISNFGKANTEKI 170
Query: 633 IDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDD 812
+ + P+A+QIEL+ L Q EL +F + I V++Y+ GS S A+ DD
Sbjct: 171 LGTCRICPAAIQIELHPYLNQKELVEFMKSKGIQVISYSSLGSAPGSSAKVR------DD 224
Query: 813 ERLVGIAQKYNKTVPQVALRF 875
+ + IA+KY Q+ L +
Sbjct: 225 KTIKAIAKKYGCAPSQIILSY 245
>UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep:
Yarrowia lipolytica chromosome B of strain CLIB122 of
Yarrowia lipolytica - Yarrowia lipolytica (Candida
lipolytica)
Length = 337
Score = 154 bits (373), Expect = 3e-36
Identities = 95/246 (38%), Positives = 137/246 (55%), Gaps = 13/246 (5%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 326
L++G IP + LGTW K +V E A+ E GY HIDTA+ Y ED VG
Sbjct: 36 LNNGKTIPAIGLGTW-----KSTTEEVAGAVECALT---EGGYRHIDTAFNYRNEDAVGL 87
Query: 327 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 506
+ + +G+KRE IF+TTK+W +YH+R V L SLE L L+YVD+ LIHWP+ +
Sbjct: 88 GIKRAMEKGVKREDIFVTTKIWVTYHDR--VEENLDMSLERLGLDYVDMLLIHWPVPLNP 145
Query: 507 N--DTLL----DNVDFLD-------TWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 647
N D + D +D TW+ M K G TKSIG+SNF+ ++ ++
Sbjct: 146 NGNDPVYPLRPDGSRDIDESGSQPKTWKQMEAVLKTGKTKSIGVSNFSIPYLEELLKEAE 205
Query: 648 EKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVG 827
P+ Q+EL+ L Q EL +FC++N+IV+ A++PFGS+ P + +E +V
Sbjct: 206 VVPAVNQVELHPLLPQLELMEFCKKNNIVMTAFSPFGSV---------GGPLLKNELVVS 256
Query: 828 IAQKYN 845
+A KYN
Sbjct: 257 LADKYN 262
>UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:
Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 153 bits (372), Expect = 4e-36
Identities = 84/226 (37%), Positives = 131/226 (57%), Gaps = 14/226 (6%)
Frame = +3
Query: 240 EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQ 416
++A A+ AGY HIDTA+ Y E VG A+ K +G+ +R+ +FI +KLW ++H E
Sbjct: 3 QRACEAAIAAGYRHIDTAFCYRNEVDVGMAIQNKIQQGIIRRQDMFIVSKLWGTHHAPED 62
Query: 417 VIPALRKSLENLNLEYVDLYLIHWPIAMF--------END--TLLDNVDFLDTWRGMIDA 566
+ KSL +L L+Y+D YL+H+P+ + E D L ++D++D WRGM
Sbjct: 63 IPVCFNKSLSDLQLDYLDQYLVHFPVGLKKVGDELFPERDGKILTTDIDYVDVWRGMEAL 122
Query: 567 KKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAY 746
K G KSIG+SNF EQI R++ P+ Q+EL+ L Q +L +C+ +I + A+
Sbjct: 123 KATGKVKSIGVSNFTMEQIDRLLSVAKIPPAVNQVELHPYLVQSDLIDYCKSKNIALTAH 182
Query: 747 TPFGSL-FPSKAQPXAPPPR--IDDERLVGIAQKYNKTVPQVALRF 875
+PFGS P + Q P ++D +V +A+K+ +T QV LR+
Sbjct: 183 SPFGSPGRPLEFQTGDEDPMGLLEDPVVVDVARKHRRTPAQVLLRY 228
>UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-like
protein 2; n=37; Euteleostomi|Rep: Aldo-keto reductase
family 1 member C-like protein 2 - Homo sapiens (Human)
Length = 320
Score = 94.7 bits (225), Expect(2) = 7e-36
Identities = 52/113 (46%), Positives = 68/113 (60%), Gaps = 1/113 (0%)
Frame = +3
Query: 159 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 338
G+IP V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 339 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
K EG ++RE +FI TKLW + H++ V A RKSL+ L L Y+DLYLIHWP+
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105
Score = 79.8 bits (188), Expect(2) = 7e-36
Identities = 47/125 (37%), Positives = 67/125 (53%), Gaps = 2/125 (1%)
Frame = +3
Query: 507 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIELN 680
N + + DFLDTW M D GL K+IG+SNFN EQ++R+++ GL KP QIE +
Sbjct: 139 NMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECH 198
Query: 681 LNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQ 860
L Q L FC+ D+ V AY P G ID+ + IA+++ K+ Q
Sbjct: 199 PYLTQKNLISFCQSRDVSVTAYRPLGG-------SCEGVDLIDNPVIKRIAKEHGKSPAQ 251
Query: 861 VALRF 875
+ +RF
Sbjct: 252 ILIRF 256
>UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA
- Apis mellifera
Length = 321
Score = 152 bits (369), Expect = 1e-35
Identities = 102/261 (39%), Positives = 142/261 (54%), Gaps = 15/261 (5%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
T+ L +G +P++ GTW + E A+ ALEAGY HIDTA Y E
Sbjct: 5 TILLPNGELMPIIGFGTWQAQE---------KELEDALNIALEAGYRHIDTATSYENEKV 55
Query: 318 VGRALTKKF-SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
+G L F S+ LKR IFI TKL + E V ++ SL+NL LEY+DLYLIH PI
Sbjct: 56 IGDVLKNWFDSKKLKRSDIFIVTKLPAVGNRAEDVEKWIKTSLQNLRLEYLDLYLIHVPI 115
Query: 495 AMFE-NDTL----------LDN-VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 638
+ D L LDN + ++ W M K G TK+IG+SNFN QI+RI+
Sbjct: 116 GFEKVGDILHPFDENGHIRLDNSTNHVEIWAEMEKQVKCGRTKAIGLSNFNISQIKRILK 175
Query: 639 SGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG--SLFPSKAQPXAPPPRIDD 812
+ K S LQIEL++ QQ EL KFC++ +I + AY+P G SL + + +
Sbjct: 176 NTKMKISMLQIELHVYFQQKELVKFCKQENIPITAYSPLGSRSLIKLLNKTEEISDMLQN 235
Query: 813 ERLVGIAQKYNKTVPQVALRF 875
+ ++ IA+KY K+ Q+ LR+
Sbjct: 236 DVVMEIAKKYKKSSAQILLRY 256
>UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2;
Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus
sp. (strain CC9311)
Length = 336
Score = 152 bits (369), Expect = 1e-35
Identities = 89/261 (34%), Positives = 145/261 (55%), Gaps = 14/261 (5%)
Frame = +3
Query: 129 IVPTLQ---LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYK 299
++PT+Q LS+G +P++ LGT K + QV +A+ + GY HID A
Sbjct: 15 VIPTMQYASLSNGDRMPLLGLGTG-----KSESRQVYKSVREAI----KIGYRHIDCASI 65
Query: 300 YGIEDQVGRALTKKF-SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLY 476
YG E++VG A+ + + R ++IT+KLW++ H + V AL +SL+NL ++Y++LY
Sbjct: 66 YGNEEEVGDAIRDAIQNHEITRSELWITSKLWSNCHGKNHVEAALSQSLQNLGVDYLNLY 125
Query: 477 LIHWPIAMFENDTLLDNVDFL---------DTWRGMIDAKKLGLTKSIGISNFNQEQIQR 629
LIHWP+ + T ++VD L +TW M + GLTK IG+SNF +++Q+
Sbjct: 126 LIHWPVGIRPEKTFAESVDDLLTPEESPISETWEAMESTRDKGLTKHIGVSNFTVKKLQQ 185
Query: 630 IIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSL-FPSKAQPXAPPPRI 806
++ +KP Q+E + LQQP L ++C +I++ AY+P GS+ P + P +
Sbjct: 186 LVSHCKQKPEVNQVEHHPLLQQPTLIEYCASEEILITAYSPLGSMDRPQSLKVKDAPAVL 245
Query: 807 DDERLVGIAQKYNKTVPQVAL 869
D + IA+ + QV L
Sbjct: 246 DHPVIRAIAETRGCSPAQVVL 266
>UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 323
Score = 152 bits (368), Expect = 1e-35
Identities = 92/258 (35%), Positives = 151/258 (58%), Gaps = 14/258 (5%)
Frame = +3
Query: 144 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 323
+L++G +IP +ALGTW + +V N AV A+E GY HID A YG E ++G
Sbjct: 9 KLNTGASIPAMALGTWQSSKE-----EVGN----AVRLAIELGYRHIDCAEIYGNEGEIG 59
Query: 324 RALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 500
AL++ +EG +KRE +F+T+KLW H + V+PA + +L+NL L+Y+DLYLIH P+A
Sbjct: 60 EALSEVLTEGKVKREELFVTSKLWCDSHHPDDVLPACQATLKNLQLDYLDLYLIHIPVAF 119
Query: 501 FENDTLLDNV----------DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 650
+ L ++ +TW+ M GL K+IG+SNF+ +++ +++++
Sbjct: 120 KKGVRLPHSIAEGIIGYTPEGVQNTWQAMEGLVAKGLCKAIGVSNFSVKRLNKLLETASI 179
Query: 651 KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS---LFPSKAQPXAPPPRIDDERL 821
P+ Q+EL+ L Q +L +FC I++ AY+P G+ L P K + P +++ +
Sbjct: 180 VPACNQVELHPYLPQEKLKEFCDSKGILLTAYSPLGNPGRLVP-KERLEREPKVMEEPVI 238
Query: 822 VGIAQKYNKTVPQVALRF 875
IA K+N +V +V LR+
Sbjct: 239 KEIAAKHNCSVARVLLRW 256
>UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Opitutaceae bacterium TAV2
Length = 334
Score = 151 bits (367), Expect = 2e-35
Identities = 99/259 (38%), Positives = 139/259 (53%), Gaps = 1/259 (0%)
Frame = +3
Query: 102 ALCFTSADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYA-LEAGYT 278
A C+T ++PTL LS G +IP + LG W Q+ +D I A AGY
Sbjct: 51 AWCYTMR--MIPTLPLSDGTSIPQLGLGVW----------QMPDDGAGVPIQAAFNAGYR 98
Query: 279 HIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNL 458
IDTA YG E+ VGRA+ + GL R+ ++ITTK+WNS + + A+R+SL L L
Sbjct: 99 AIDTAPIYGNEEGVGRAIR---ASGLPRKELYITTKVWNSAQGYDSTLRAVRESLGRLQL 155
Query: 459 EYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 638
EYVDLYLIHWP+ + ++DTW+ + K GL +SIG+SNF +QR+ D
Sbjct: 156 EYVDLYLIHWPVPKIDR--------YVDTWKALAKIKADGLARSIGVSNFTPVYLQRLFD 207
Query: 639 SGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
P Q+EL+ LQQ EL F ++ IV A++P G + D
Sbjct: 208 ETGIVPVVNQVELHPRLQQHELRAFHAKHRIVTEAWSPLGQ-----------GTLLADPV 256
Query: 819 LVGIAQKYNKTVPQVALRF 875
L GIAQK+ ++ QV +R+
Sbjct: 257 LAGIAQKHGRSAAQVIIRW 275
>UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 339
Score = 151 bits (366), Expect = 2e-35
Identities = 86/265 (32%), Positives = 144/265 (54%), Gaps = 16/265 (6%)
Frame = +3
Query: 129 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 308
I T+ L+SG +PV+ GTW PK + D ALEAGY HID+A +
Sbjct: 3 IADTVTLNSGYEMPVIGYGTW--QLPKNLAAERVRD-------ALEAGYRHIDSALSFKN 53
Query: 309 EDQVGRALTKKFS-EGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 485
+++V + ++RE +F+++K+WN+YH R + + + + LE Y+DL +IH
Sbjct: 54 QEEVAAGIKDWCKIRKVRREELFLSSKIWNTYHSRNRCMQQIDEMLEIFETTYMDLIVIH 113
Query: 486 WPIAMFENDT---------------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQ 620
WP E++ +VD+L+TW+ + DA + G +SIG++NFN Q
Sbjct: 114 WPFGWAEDEPPGERGLWPRGANGKMRYSDVDYLETWKALEDAHRSGKIRSIGLANFNIGQ 173
Query: 621 IQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPP 800
++++ GL KP+ LQ+E+N L Q E+ +FCRE I++ A+ G+ + + P
Sbjct: 174 VEQVWTKGLIKPAVLQVEMNPFLDQEEIRQFCREKGIILTAFMLTGNPGSALYRKHEDPN 233
Query: 801 RIDDERLVGIAQKYNKTVPQVALRF 875
+ +E L IA+ + K+V QV +R+
Sbjct: 234 LLYNETLQSIAKGHGKSVVQVLVRW 258
>UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate
dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent
D-sorbitol-6-phosphate dehydrogenase - Malus domestica
(Apple) (Malus sylvestris)
Length = 310
Score = 151 bits (365), Expect = 3e-35
Identities = 91/261 (34%), Positives = 139/261 (53%), Gaps = 15/261 (5%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
T+ LSSG +PV+ LG W + ++ ++ ++ A++ GY H D A Y E
Sbjct: 3 TVTLSSGYEMPVIGLGLWRLEK---------DELKEVILNAIKIGYRHFDCAAHYKSEAD 53
Query: 318 VGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG AL + F GL KRE +FITTK+WNS H V+ A + SLE L ++Y+DLYL+H+P+
Sbjct: 54 VGEALAEAFKTGLVKREELFITTKIWNSDHGH--VVEACKNSLEKLQIDYLDLYLVHYPM 111
Query: 495 -----------AMFENDTLLD---NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI 632
++ D +LD + TW GM LGL +SIG+SN+ +
Sbjct: 112 PTKHNAIGKTASLLGEDKVLDIDVTISLQQTWEGMEKTVSLGLVRSIGLSNYELFLTRDC 171
Query: 633 IDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDD 812
+ KP+ Q E + Q+ L KFC ++ ++ A+TP G +K + P +DD
Sbjct: 172 LAYSKIKPAVSQFETHPYFQRDSLVKFCMKHGVLPTAHTPLGGAAANKDMFGSVSP-LDD 230
Query: 813 ERLVGIAQKYNKTVPQVALRF 875
L +A+KY K+V Q+ LR+
Sbjct: 231 PVLNDVAKKYGKSVAQICLRW 251
>UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 286
Score = 150 bits (364), Expect = 4e-35
Identities = 96/256 (37%), Positives = 141/256 (55%), Gaps = 2/256 (0%)
Frame = +3
Query: 114 TSADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTA 293
T+ + T L++G IP+V GTW P G+V +V+ AL+AGY HIDTA
Sbjct: 2 TALTKLTDTYTLNNGTKIPIVGFGTW--QTPDGQVAY------DSVLAALKAGYRHIDTA 53
Query: 294 YKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDL 473
YG E+ VG+A+ G+ RE +F+TTKLWN+ H + AL SL L L+YVDL
Sbjct: 54 AAYGNEESVGKAIA---DSGVAREDLFVTTKLWNADHGYDAAKKALDTSLAKLGLDYVDL 110
Query: 474 YLIHW--PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 647
YLIHW P AM +N L+ DTWR M +A ++IG+SNF + + ++ +
Sbjct: 111 YLIHWPNPAAMRDNWEQLN----ADTWRAMEEAYTARKARAIGVSNFRPKHLDALLKTAK 166
Query: 648 EKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVG 827
P+ QI LN + + E+ + R++DI+ AY+P G+ + + P L
Sbjct: 167 VVPAVNQIFLNPSDMEDEVVAYNRKHDILSEAYSPLGT-----GKIFSIP------ELKT 215
Query: 828 IAQKYNKTVPQVALRF 875
+A KY+K+V QV LR+
Sbjct: 216 LADKYDKSVAQVVLRW 231
>UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG03517.1 - Gibberella zeae PH-1
Length = 364
Score = 149 bits (362), Expect = 7e-35
Identities = 90/237 (37%), Positives = 132/237 (55%), Gaps = 1/237 (0%)
Frame = +3
Query: 162 NIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKK 341
+IP LGTWL KG VV AV YAL+ GY HIDTA + ED+VG+ +
Sbjct: 59 DIPAFGLGTWLAG--KGVVVP-------AVEYALKGGYRHIDTALIWRNEDEVGKGIK-- 107
Query: 342 FSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF-ENDTL 518
+ G+ R+ I++T KLWN+ H E V A+ S+ NL +EY+DLYLIH+P+A E +
Sbjct: 108 -ASGVSRDEIWVTGKLWNTDHRPELVRKAIETSIANLGVEYLDLYLIHYPVAWVPETRDV 166
Query: 519 LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQP 698
+N +DTW+ M + + GLT++IG SNF + I +I+ +P A + E + LQQ
Sbjct: 167 DNNTSLIDTWKAMEELVRAGLTRNIGFSNFAPKDINKILKIASIQPYAHEFETHPYLQQQ 226
Query: 699 ELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQVAL 869
F ++ +I V+A +P + P+ P + DE V +A+ N TV Q L
Sbjct: 227 SFVDFHKKENIKVIAASPLANTNPTYGDKY--PSILHDEFWVKLAEDKNATVAQTIL 281
>UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 323
Score = 149 bits (361), Expect = 9e-35
Identities = 84/215 (39%), Positives = 123/215 (57%), Gaps = 10/215 (4%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 326
+++G IP V GTW + K ++V N AV AL GY HID A Y E +VG
Sbjct: 9 INTGAKIPAVGFGTW-----QAKPLEVEN----AVEVALREGYRHIDCAAIYRNETEVGN 59
Query: 327 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM-- 500
+ K G+ RE IFIT KLWN+ H E V PAL K+L++L + Y+DLYL+HWP A
Sbjct: 60 GIRKS---GVPREEIFITGKLWNTKHAPEDVEPALDKTLQDLGVAYLDLYLMHWPCAFKG 116
Query: 501 ------FENDTLLD--NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKP 656
+D + D N+D++ T+R M G ++IG+SNFN +++ ++ P
Sbjct: 117 GDKWFPLNDDGVFDLANIDYITTYRAMEKLLATGKVRAIGVSNFNIRRLEELLGQVSVVP 176
Query: 657 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 761
+ QIE + LQQP+L +FC+ I++ AY+P G+
Sbjct: 177 AVNQIEAHPYLQQPDLLQFCQSKGILIEAYSPLGN 211
>UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep:
Protein GCY - Saccharomyces cerevisiae (Baker's yeast)
Length = 312
Score = 148 bits (359), Expect = 2e-34
Identities = 92/227 (40%), Positives = 128/227 (56%), Gaps = 20/227 (8%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
L L++G IP + LGTW ND +AV+ AL+ GY HIDTA Y EDQV
Sbjct: 12 LSLNTGAQIPQIGLGTWQSKE---------NDAYKAVLTALKDGYRHIDTAAIYRNEDQV 62
Query: 321 GRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI-- 494
G+A+ G+ RE IF+TTKLW + H +V AL +SL+ L L+YVDLYL+HWP
Sbjct: 63 GQAIK---DSGVPREEIFVTTKLWCTQHHEPEV--ALDQSLKRLGLDYVDLYLMHWPARL 117
Query: 495 --AMFENDTLLD--------------NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQ 626
A +N+ +L N +F+ TW M + K G TK++G+SNF+ ++
Sbjct: 118 DPAYIKNEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLK 177
Query: 627 RIIDSGLEK--PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 761
++ S K P+A Q+E++ L Q EL FC+ IVV AY+P GS
Sbjct: 178 DLLASQGNKLTPAANQVEIHPLLPQDELINFCKSKGIVVEAYSPLGS 224
>UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreductase
1; n=32; Eukaryota|Rep: Probable NAD(P)H-dependent
oxidoreductase 1 - Oryza sativa subsp. japonica (Rice)
Length = 321
Score = 148 bits (358), Expect = 2e-34
Identities = 77/226 (34%), Positives = 126/226 (55%), Gaps = 10/226 (4%)
Frame = +3
Query: 228 TNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL--KRESIFITTKLWNSY 401
+ DT A++ A+E GY H DTA Y E VG A+ + GL R +F+T+K+W S
Sbjct: 31 SEDTTAAMLRAIELGYRHFDTARIYATEGCVGEAVAEAVRRGLIASRADVFVTSKIWCSD 90
Query: 402 HEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--------FENDTLLDNVDFLDTWRGM 557
+V+PA R++L NL ++YVDL L+HWP+++ F + +L + D WRGM
Sbjct: 91 LHAGRVVPAARETLRNLGMDYVDLLLVHWPVSLTPGNYDFPFPKEVILPSFDMEGVWRGM 150
Query: 558 IDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVV 737
+ +LGL ++IG+SNF+ +++++++ +P+ Q+E+N QQ L + CR + +
Sbjct: 151 EECHRLGLARAIGVSNFSAKKLEQLLSLAAVRPAVNQVEVNPMWQQRTLREVCRREGVQL 210
Query: 738 MAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQVALRF 875
Y+P G +K P +D L IA KT+ Q+ LR+
Sbjct: 211 CGYSPLG----AKGTPWGSAAVMDSGVLQEIAGAKGKTLAQICLRW 252
>UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep:
CG2767-PA - Drosophila melanogaster (Fruit fly)
Length = 329
Score = 147 bits (356), Expect = 4e-34
Identities = 96/263 (36%), Positives = 141/263 (53%), Gaps = 18/263 (6%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
L ++G +PV+ +GTW + E A+ ALEAGY HIDTA YG E +
Sbjct: 7 LTFNNGEKMPVIGIGTWQAS---------DEEIETAIDAALEAGYRHIDTAPVYGNEKAI 57
Query: 321 GRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
GR L + G +KRE +FI TK+ + +V P ++KSLE+L L+YVDLYL+H P
Sbjct: 58 GRVLKRWLDAGKVKREELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFT 117
Query: 498 MFENDT---LLDNVDFLDT---------WRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS 641
+ N+ LD ++ W M + GLTKSIG+SNF+++Q+ R++ +
Sbjct: 118 ININEDGSFKLDKEGLMEVDVTTNHAAIWVAMEALVEKGLTKSIGVSNFSKDQVARLLKN 177
Query: 642 GLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAP-----PPRI 806
+P+ QIE ++ LQQ +L FC+ +I V AY+P GS +K A P +
Sbjct: 178 CKIRPANNQIEHHVYLQQRDLVDFCKSENITVTAYSPLGSKGIAKFNAGAGIVRDLPDLM 237
Query: 807 DDERLVGIAQKYNKTVPQVALRF 875
D + IA + KT QV LR+
Sbjct: 238 DIPEVKEIAASHGKTPAQVLLRW 260
>UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose
reductase; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to aldose reductase -
Strongylocentrotus purpuratus
Length = 274
Score = 147 bits (355), Expect = 5e-34
Identities = 83/214 (38%), Positives = 127/214 (59%), Gaps = 2/214 (0%)
Frame = +3
Query: 240 EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQ 416
E AV A++ GY HID A+ YG E +VG L +KF + KRE IFIT+KLWN+ H +
Sbjct: 13 EAAVKAAIDCGYRHIDCAHVYGNEAEVGAGLKEKFDANVVKREDIFITSKLWNNKHHPDD 72
Query: 417 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 596
V A +L+NL L YVDLYL+HWP+A + L+ + G K+IG
Sbjct: 73 VEQACDITLKNLQLSYVDLYLMHWPMAYQAMEKLVTS----------------GKCKAIG 116
Query: 597 ISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSK 776
+SNF+ + ++R+I+ +P+ LQ+EL+ L Q +L +FC+E+++ V AY+P G+ P +
Sbjct: 117 LSNFSMKMMKRVIEKATIQPANLQVELHPLLTQEKLIEFCKEHNMTVTAYSPLGA--PDR 174
Query: 777 AQPXAPPPRI-DDERLVGIAQKYNKTVPQVALRF 875
P++ +D + GIA K K+ Q+ +RF
Sbjct: 175 PWVKDDDPKLMEDPIVTGIATKKGKSPAQILIRF 208
>UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate
division TM7 genomosp. GTL1|Rep: Aldehyde reductase -
candidate division TM7 genomosp. GTL1
Length = 299
Score = 146 bits (354), Expect = 7e-34
Identities = 92/256 (35%), Positives = 135/256 (52%), Gaps = 11/256 (4%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
L L + +P++ GTW P G T V A++AGY HID A YG E +V
Sbjct: 4 LTLRNKQTLPLLGYGTW--ELPTGT-------TADLVETAIKAGYRHIDCAMIYGNEKEV 54
Query: 321 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
G + + +G+ KRE +F+T+KLWN+ H + V A RK+L +L L+Y+DLYLIHW +A
Sbjct: 55 GEGIRRTIDQGVVKREDLFVTSKLWNTDHAQVDVGVACRKTLNDLGLDYLDLYLIHWGVA 114
Query: 498 MFENDTL--LDN--------VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 647
D L LD+ + +TW+ M + + GL KS+G++NF + ++
Sbjct: 115 FEHGDNLEPLDDDGVAKFSFISMKETWQAMEELVEQGLVKSMGVANFTAPMLLDLLSYAK 174
Query: 648 EKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVG 827
KP+ QIEL+ L Q +L FC +I V AY+PFGS P + D +
Sbjct: 175 IKPAVHQIELHPYLAQNDLVAFCYSQNIAVTAYSPFGS---------TEAPVLTDPTVKE 225
Query: 828 IAQKYNKTVPQVALRF 875
+A+ KT QV LR+
Sbjct: 226 VAKGLGKTPAQVLLRW 241
>UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus acidophilus
Length = 285
Score = 145 bits (352), Expect = 1e-33
Identities = 81/208 (38%), Positives = 123/208 (59%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
T L++G IP++ GTW P G+V E++V+ AL GY HIDTA YG ED
Sbjct: 9 TYTLNNGVKIPIIGFGTW--QTPDGEVA------EESVLAALNCGYRHIDTASAYGNEDS 60
Query: 318 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
VGRA+ K G+ R +FITTKLWNS H E+ A+ +SL +L L+Y+D+YLIHWP
Sbjct: 61 VGRAIQKS---GINRHELFITTKLWNSDHGYEKTKKAIDQSLLDLKLDYLDMYLIHWPNP 117
Query: 498 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 677
D + ++ ++WR M +A + G ++IG+SNF + + ++++ KP QI L
Sbjct: 118 SSMRDHWAE-IN-AESWRAMEEAVRAGKIRAIGVSNFRKHHLDALMETAEIKPVVNQIFL 175
Query: 678 NLNLQQPELFKFCRENDIVVMAYTPFGS 761
N + Q E+ ++ D++ AY+P G+
Sbjct: 176 NPSDLQSEVVTENKKLDLLSEAYSPLGT 203
>UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep:
Aldehyde reductase - gamma proteobacterium HTCC2207
Length = 330
Score = 145 bits (352), Expect = 1e-33
Identities = 93/269 (34%), Positives = 143/269 (53%), Gaps = 21/269 (7%)
Frame = +3
Query: 132 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 311
VP +++SS ++P V LG W K+ Q + QAV A++ GY H+D+A YG E
Sbjct: 7 VPGVKVSSK-SMPAVGLGLW-------KITQ--DSAAQAVYEAIKVGYRHLDSAADYGNE 56
Query: 312 DQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 488
QVG + + +EGL RE ++ITTKLWN+YH E V A R+S+++L L+Y+DLYL+H+
Sbjct: 57 QQVGEGIARAIAEGLCSREELWITTKLWNTYHRAEHVEAACRRSMDDLGLDYIDLYLVHF 116
Query: 489 PIAM--------------FENDT-----LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFN 611
PIA+ F++ LD V +TW M + GL + IG+ N++
Sbjct: 117 PIALRYVDFNDRYPAEWIFDHSAEDPAMELDQVPLSETWGAMEQLVESGLVRQIGVCNYS 176
Query: 612 QEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSL-FPSKAQPX 788
+ ++ KP+ LQIE + L Q L + R ++ V A++P GSL +
Sbjct: 177 AVLLHDLMSYARIKPAMLQIESHPYLTQEALLRTARSYNMAVTAFSPLGSLSYVELNMAG 236
Query: 789 APPPRIDDERLVGIAQKYNKTVPQVALRF 875
A + D ++ AQ+ T QV LR+
Sbjct: 237 ANDTVLTDPSVLAAAQRNGVTAAQVVLRW 265
>UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2;
Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid
reductase - Tropheryma whipplei (strain Twist)
(Whipple's bacillus)
Length = 283
Score = 144 bits (350), Expect = 2e-33
Identities = 97/248 (39%), Positives = 133/248 (53%)
Frame = +3
Query: 132 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 311
VP++ L G +IP LGT+ P N+ V A+E GY HIDTA Y E
Sbjct: 9 VPSVLLGDGVSIPQFGLGTY--ELPP-------NEASSVVQSAIELGYRHIDTASLYANE 59
Query: 312 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 491
+VGRA+ S G+KRE F+TTKLWNS + + A +SL+ L+L+YVDLYLIHWP
Sbjct: 60 REVGRAIA---SSGIKREEFFVTTKLWNSDQPKPR--EAFERSLDLLSLDYVDLYLIHWP 114
Query: 492 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 671
E +++ W +++ K+ G KS+G+SNF E I +I ++G PS QI
Sbjct: 115 CPPSEL--------YINVWEVLLELKESGRAKSVGVSNFLSEHIDKIKEAGFPLPSVNQI 166
Query: 672 ELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKT 851
EL+ LQQ EL CR + I + ++ PF SK P L A++Y KT
Sbjct: 167 ELHPWLQQRELVLSCRNDGIQIESWGPFARF--SKDLDAFP-------ELTRPAKQYGKT 217
Query: 852 VPQVALRF 875
QV LR+
Sbjct: 218 PAQVILRW 225
>UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreductase
2; n=6; Magnoliophyta|Rep: Probable NAD(P)H-dependent
oxidoreductase 2 - Oryza sativa subsp. japonica (Rice)
Length = 322
Score = 144 bits (350), Expect = 2e-33
Identities = 77/226 (34%), Positives = 124/226 (54%), Gaps = 10/226 (4%)
Frame = +3
Query: 228 TNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL--KRESIFITTKLWNSY 401
+ +T A++ A+E GY H DTA Y E V A+ + GL R +F+T+KLW S
Sbjct: 33 SEETTAALLRAIELGYRHFDTARLYATEGCVSEAVAEAVRRGLVASRADVFVTSKLWCSD 92
Query: 402 HEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--------FENDTLLDNVDFLDTWRGM 557
+V+PA R++L NL ++YVDL L+HWP + F + + D WRGM
Sbjct: 93 LHAGRVVPAARETLRNLGMDYVDLLLVHWPATVAPGSYDFPFPKEEMAPAFDMEGVWRGM 152
Query: 558 IDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVV 737
+ +LGL ++IG+SNF+ +++++++ + +P+A Q+E+N QQ L + CR + +
Sbjct: 153 EECHRLGLARAIGVSNFSAKKLEQLLSFAVVRPAANQVEMNPMWQQRTLREVCRREGVQL 212
Query: 738 MAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQVALRF 875
Y+P G +K P +D L IAQ KT+ Q+ LR+
Sbjct: 213 CGYSPLG----AKGTPWGSAAVMDSGVLHDIAQTKGKTLAQICLRW 254
>UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase
family; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 307
Score = 144 bits (348), Expect = 3e-33
Identities = 92/250 (36%), Positives = 136/250 (54%), Gaps = 7/250 (2%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 326
L++G +P + LGTWL + +AV ALE GY ID A Y E ++G
Sbjct: 8 LNNGKFMPAIGLGTWLA---------APGEVGKAVTLALENGYRLIDCARFYKNEKEIGE 58
Query: 327 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 506
+ F + RE +F+T+KLW R + + +S+++L +Y+DLYLIHWPIA+
Sbjct: 59 MGIEPFLKNHPREELFVTSKLWMDQVTR--IRESCLESIQDLKCKYLDLYLIHWPIALKV 116
Query: 507 N-------DTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL 665
+ + LD +D + W+ M GL KSIG+SNF QI++I+ KP
Sbjct: 117 DASNPPKPEDFLD-MDITEIWQEMERLVDEGLVKSIGLSNFTIPQIEKIMKMCRIKPVIN 175
Query: 666 QIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYN 845
Q+ELN+ LQQ +L + C+ +IVV AY P G K + +DDE +V +A+KYN
Sbjct: 176 QVELNVYLQQNKLREVCKSYNIVVEAYRPIG----GKPANESDKNCLDDEVVVSLAKKYN 231
Query: 846 KTVPQVALRF 875
KT Q+ LR+
Sbjct: 232 KTTAQICLRW 241
>UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28;
Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza
sativa (Rice)
Length = 323
Score = 144 bits (348), Expect = 3e-33
Identities = 91/258 (35%), Positives = 135/258 (52%), Gaps = 10/258 (3%)
Frame = +3
Query: 132 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 311
VP + L G P+ A+G +G T A + ALE G+ H DTA YG E
Sbjct: 4 VPEVALRHGAGRPMPAVG--VGTADSAATSPETK--RGAALAALEVGFRHFDTAALYGTE 59
Query: 312 DQVGRALTKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 485
+G A+ + GL RE +F+TTKLW + V+P+LR+SL NL +EYVDLYL+H
Sbjct: 60 APLGEAIAEATRRGLVASREEVFVTTKLWCTQCHPGLVLPSLRESLRNLQMEYVDLYLVH 119
Query: 486 WPIAMFENDTLL-----DNV--DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSG 644
WPI++ +L D V DF WR M + +LGL K+IG+SNF + + +++
Sbjct: 120 WPISVKPGPPMLPVKREDAVPFDFEGVWRAMEECHRLGLAKAIGVSNFTTKHLDKLLAVA 179
Query: 645 LEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSL-FPSKAQPXAPPPRIDDERL 821
P+ Q+E+N QQ + ++C I V AY+P G + + P + D
Sbjct: 180 TIPPAVNQVEMNPVWQQRTVREYCAAKGIRVAAYSPLGGQNWIGEGNDVMESPVLAD--- 236
Query: 822 VGIAQKYNKTVPQVALRF 875
IA+ K++ QV+LR+
Sbjct: 237 --IARARGKSIAQVSLRW 252
>UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa (japonica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. japonica
(Rice)
Length = 288
Score = 143 bits (347), Expect = 5e-33
Identities = 87/257 (33%), Positives = 144/257 (56%), Gaps = 12/257 (4%)
Frame = +3
Query: 132 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 311
+P LSSG +P V +GT P G T + V+ A+EAGY H DTA Y E
Sbjct: 1 MPEAALSSGKPMPRVGMGT--ASFPLGATDPST--VKDVVLRAIEAGYRHFDTAAVYQTE 56
Query: 312 DQVGRALTKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 485
+G A+ + GL R+ ++IT+KLW ++ V+P+LR++L + +EY+DLYLIH
Sbjct: 57 AILGDAVAEAVRAGLVASRDELYITSKLWVAHAHPGHVLPSLRRALRKMQMEYLDLYLIH 116
Query: 486 WPIAM----------FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII 635
+P++M + D L+ +D W+ M + ++LGLTK+IG+SNF+ ++++ ++
Sbjct: 117 FPVSMRLAEDPESMTYSKDDLV-MMDMEGVWKEMEECQRLGLTKAIGVSNFSCKKLETLL 175
Query: 636 DSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDE 815
P+A Q+E++ +Q +L +FC+E I + AY+P G K P + +D
Sbjct: 176 SFATISPAANQVEVHPYCRQNKLREFCKEKGIQLCAYSPLG----GKGTPWSNNAVMDCP 231
Query: 816 RLVGIAQKYNKTVPQVA 866
L IA + KT+ Q++
Sbjct: 232 LLKQIAMERGKTIAQIS 248
>UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14;
Dikarya|Rep: Aldo-keto reductase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 353
Score = 143 bits (347), Expect = 5e-33
Identities = 97/269 (36%), Positives = 142/269 (52%), Gaps = 14/269 (5%)
Frame = +3
Query: 111 FTSADLIVPT-LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHID 287
F S + PT +L++G +IP + LGTW + K +V QAV +AL+AGY HID
Sbjct: 28 FNSLIMSAPTSFKLNTGASIPAIGLGTW-----QAKAGEV----RQAVAHALKAGYRHID 78
Query: 288 TAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 467
A Y ED+VG + G+ R IF+T+K+W+SYH+R V L +L++L +Y+
Sbjct: 79 GALCYQNEDEVGLGIK---DSGVPRSEIFLTSKVWSSYHDR--VEECLDTTLKSLQTDYL 133
Query: 468 DLYLIHWPIAMFENDT------------LLD-NVDFLDTWRGMIDAKKLGLTKSIGISNF 608
DLYLIHWP+ + N T LD + D TW M D K G K+IG+SN
Sbjct: 134 DLYLIHWPVRLAPNGTHPLFPVKPDGSRNLDWDWDQAKTWAQMEDVLKKGKAKAIGLSNA 193
Query: 609 NQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPX 788
I+ II +G P+ Q+EL+ Q L K+C+E I++ AY+P GS
Sbjct: 194 GIPIIEHIIKTGKVTPAVNQVELHPYCPQHALLKYCKEKGILLEAYSPLGS--------- 244
Query: 789 APPPRIDDERLVGIAQKYNKTVPQVALRF 875
P +D L+ +A+K+N V + +
Sbjct: 245 TSSPLHEDPDLLAVAKKHNVPTATVLISY 273
>UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452
protein; n=6; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to LOC553452 protein -
Strongylocentrotus purpuratus
Length = 321
Score = 143 bits (346), Expect = 6e-33
Identities = 91/260 (35%), Positives = 141/260 (54%), Gaps = 17/260 (6%)
Frame = +3
Query: 147 LSSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 323
L G +P++ GTW + G+V++ A++ GY HID A YG E VG
Sbjct: 10 LPGGRKLPLLGFGTWQIKPEEVGRVIET----------AIDCGYRHIDEASLYGNEKGVG 59
Query: 324 RALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA- 497
+ K +G +KRE +F+T+KLW + +V P+ R+SL +L L Y+DL+LIH P +
Sbjct: 60 DGIKAKIDDGTIKREDLFVTSKLWVTDSHPSRVEPSCRQSLSDLGLAYLDLFLIHCPTSA 119
Query: 498 --------MFENDTLL--DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 647
M +N + D +D++DTWR M GL ++IG+SNF QIQR++D
Sbjct: 120 VGGKGPFPMDDNGLFIGDDTIDYVDTWRIMESLVDKGLVRAIGVSNFTVAQIQRVLDLPP 179
Query: 648 EKPSA-LQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKA---QPXAPPPRIDDE 815
+ P A +Q+E + L Q EL +FC++ I V AY+P GS P + + P ++D
Sbjct: 180 KYPIANVQVECHPFLAQNELIEFCKKQGITVTAYSPLGS--PERVLQKRATTDPLLMEDP 237
Query: 816 RLVGIAQKYNKTVPQVALRF 875
+ IA+K + QV +R+
Sbjct: 238 VVCAIAKKKGVSPAQVLIRY 257
>UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep:
Aldehyde reductase 1 - Sporobolomyces salmonicolor
Length = 323
Score = 143 bits (346), Expect = 6e-33
Identities = 85/226 (37%), Positives = 125/226 (55%), Gaps = 15/226 (6%)
Frame = +3
Query: 129 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 308
+V T L++G ++ +V GTW + Q V A+E GY H+D A Y
Sbjct: 1 MVGTTTLNTGASLELVGYGTWQA---------APGEVGQGVKVAIETGYRHLDLAKVYSN 51
Query: 309 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 488
+ +VG A+ + G+KRE +FIT+KLWN+ H EQV PAL +L+ L LEY+DLYLIHW
Sbjct: 52 QPEVGAAIKEA---GVKREDLFITSKLWNNSHRPEQVEPALDDTLKELGLEYLDLYLIHW 108
Query: 489 PIA----------MF----ENDTLLD-NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQI 623
P+A +F + + LD V +DTW+ M+ G K+IG+SNF+ + +
Sbjct: 109 PVAFPPEGDITQNLFPKANDKEVKLDLEVSLVDTWKAMVKLLDTGKVKAIGVSNFDAKMV 168
Query: 624 QRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 761
II++ PS QIE + L QPEL + +I + AY+P G+
Sbjct: 169 DAIIEATGVTPSVNQIERHPLLLQPELIAHHKAKNIHITAYSPLGN 214
>UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein T08H10.1 - Caenorhabditis elegans
Length = 333
Score = 142 bits (343), Expect = 1e-32
Identities = 95/266 (35%), Positives = 140/266 (52%), Gaps = 17/266 (6%)
Frame = +3
Query: 126 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY--ALEAGYTHIDTAYK 299
+ V ++ L++G +P+ LGTW QV ++ E V AL+AGY IDTA+
Sbjct: 1 MTVDSIPLNTGAQLPLFGLGTW----------QVKDEAELTVALRAALDAGYRLIDTAHL 50
Query: 300 YGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLY 476
Y E +G+ L + S G LKRE IF+T+KL + H E V + L+ L LEY+DLY
Sbjct: 51 YQNEHIIGKVLHEYISSGKLKREDIFVTSKLPFTAHAPEDVPKCVESQLKALQLEYIDLY 110
Query: 477 LIHWPIA----------MFENDTL-LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQI 623
LIH P + EN L + + +DTWR + K G K++G+SNF+ Q+
Sbjct: 111 LIHCPFPFKHQEGSFAPLMENGELAVTEIAHIDTWRALEKLYKEGKLKALGVSNFSCNQL 170
Query: 624 QRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPR 803
Q + D+ KP+ Q+E ++ Q EL C++ + V AY P GS A+P P
Sbjct: 171 QALYDAAEVKPANQQVECHIYWPQQELRALCKKLGVTVTAYAPLGSPGRKAARPDGVWPE 230
Query: 804 IDD--ERLV-GIAQKYNKTVPQVALR 872
D E +V +A KY+KT Q+ +R
Sbjct: 231 GDPLLEPIVKQLAAKYHKTAAQILIR 256
>UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=5;
Pezizomycotina|Rep: D-xylose reductase (Xyl1), putative
- Neosartorya fischeri (strain ATCC 1020 / DSM 3700 /
NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 /
DSM 3700 / NRRL 181))
Length = 321
Score = 142 bits (343), Expect = 1e-32
Identities = 93/270 (34%), Positives = 142/270 (52%), Gaps = 20/270 (7%)
Frame = +3
Query: 126 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY-ALEAGYTHIDTAYKY 302
+ P+ +L+SG ++P+V G W +V N+T IY A++AGY D A Y
Sbjct: 1 MTTPSTKLNSGYDMPLVGFGLW----------KVNNETCADQIYHAIKAGYRLFDGACDY 50
Query: 303 GIEDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYL 479
G E + G+ + + EG+ KRE +FI +KLWNS+H+ ++V P RK L + L+Y DL++
Sbjct: 51 GNEVEAGKGVARAIQEGIVKREDLFIVSKLWNSFHDGDRVEPICRKQLADWGLDYFDLFI 110
Query: 480 IHWPIAM--------------FENDTL-LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQ 614
+H+PIA+ EN+ L N +TW M L +SIG+SNF+
Sbjct: 111 VHFPIALKYVDPAVRYPPGWLSENNKLEFSNASIQETWTAMESLVDKKLARSIGVSNFSA 170
Query: 615 EQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSL-FPSKAQPXA 791
+ + ++ +P+ LQIE + L Q L + ++ I V AY+ FG L F A
Sbjct: 171 QLLMDLLRYARIRPATLQIEHHPYLTQERLVTYAQKEGIAVTAYSSFGPLSFVELDLKDA 230
Query: 792 --PPPRIDDERLVGIAQKYNKTVPQVALRF 875
P D + + GIAQK+ KT QV LR+
Sbjct: 231 HETPKLFDHDVIKGIAQKHGKTPAQVLLRW 260
>UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 353
Score = 141 bits (342), Expect = 2e-32
Identities = 101/260 (38%), Positives = 139/260 (53%), Gaps = 18/260 (6%)
Frame = +3
Query: 144 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 323
+LSSG N P+V LGT H V+ E + ALE G HIDT++ Y E+ +G
Sbjct: 32 RLSSGHNFPIVGLGT---HGLNEDVL------ETVLTGALEKGIGHIDTSFVYKNEETIG 82
Query: 324 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM- 500
+ L F++G KRE IF+T+KL + E V ++ SLE L L+Y+D+YLIH P A+
Sbjct: 83 KVLKDWFAKGGKREDIFVTSKLPYYDNHPESVEKYIKLSLEKLGLQYLDMYLIHAPFAVH 142
Query: 501 -----FENDTLLDNVDFLDT-------WRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSG 644
+E T D LDT W+ M K G TKSIG+SNFN+ QI I+
Sbjct: 143 HKEDSYELATNEDGSVVLDTQTDPIAVWKEMEKQVKEGRTKSIGLSNFNETQITNILKEA 202
Query: 645 LEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSK----AQPXAPPPRIDD 812
KPS LQ+E++ QQ L +FC++N I+V Y P GS K Q P +
Sbjct: 203 KIKPSNLQVEVHAYHQQKPLIEFCQKNGIIVTGYAPLGSPGARKELHPGQMEEEFPDVFK 262
Query: 813 ERLVG-IAQKYNKTVPQVAL 869
+V IA+K+ K+V Q+ L
Sbjct: 263 LPVVNEIAKKHGKSVVQILL 282
>UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 321
Score = 140 bits (340), Expect = 3e-32
Identities = 85/222 (38%), Positives = 125/222 (56%), Gaps = 17/222 (7%)
Frame = +3
Query: 144 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 323
+L+ G IP + LGT+ P G+V N+ AL+ GY HID A YG E +G
Sbjct: 18 KLNDGNQIPSIGLGTYYSENP-GEVGDAINN-------ALKNGYRHIDGAAFYGNEKVIG 69
Query: 324 RALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 500
+L + F EG +KRE IF T+KLWNS H V+ K++E+L + Y+DLYLIHWPIA
Sbjct: 70 NSLKEIFKEGEIKREDIFYTSKLWNSCHNSNLVVKHCVKTIEDLGIGYLDLYLIHWPIA- 128
Query: 501 FEN----------------DTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI 632
FEN + ++ V +TW+ M +LGL KSIG+SNFN + + +
Sbjct: 129 FENSNPLGLTIEPLRDQNGNPIIAPVSIRETWQEMEKLVELGLVKSIGVSNFNVQNLVDL 188
Query: 633 IDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 758
+ KP Q+E++ L Q +L ++C + +I ++AY+P G
Sbjct: 189 LTYAKIKPVVNQVEIHPYLTQFKLQEYCDKYEIKLVAYSPLG 230
>UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila
melanogaster|Rep: CG40064-PA - Drosophila melanogaster
(Fruit fly)
Length = 361
Score = 140 bits (339), Expect = 4e-32
Identities = 73/172 (42%), Positives = 100/172 (58%), Gaps = 12/172 (6%)
Frame = +3
Query: 246 AVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVI 422
AV A+E G+ H DTAY Y E ++G AL + G + RE+IF+TTKLWN++H+ V
Sbjct: 49 AVHCAIETGFRHFDTAYYYENEKEIGEALRTQIKMGNISRENIFLTTKLWNTHHDPRDVR 108
Query: 423 PALRKSLENLNLEYVDLYLIHWPIA-----------MFENDTLLDNVDFLDTWRGMIDAK 569
K LE L Y+DLYL+H+P+ M ++ +D+LDTWR M +
Sbjct: 109 RICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPMSGDELQTVEIDYLDTWRAMENLV 168
Query: 570 KLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCREN 725
KLG+ +SIG+SNFN EQIQRII KP Q+E+ Q +L +CR N
Sbjct: 169 KLGMVRSIGLSNFNMEQIQRIIQCSSSKPVVNQVEIWPGFLQKDLVDYCRYN 220
>UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3;
Lactobacillus|Rep: 2,5-didehydrogluconate reductase -
Lactobacillus reuteri 100-23
Length = 288
Score = 140 bits (338), Expect = 6e-32
Identities = 90/248 (36%), Positives = 131/248 (52%), Gaps = 2/248 (0%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
T L++G IP V GT+ R V EQAV A+E GY HIDTA YG E+
Sbjct: 10 TFNLNNGVKIPCVGYGTF---RTPADVA------EQAVKEAIETGYRHIDTAAVYGNEEA 60
Query: 318 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI- 494
VG+ + G+KRE +F+T+KLWN+ EQ A +++L+ L ++Y+DLYLIHWP
Sbjct: 61 VGKGIK---DSGIKREDLFVTSKLWNTNRGYEQTKKAFQETLDRLQMDYLDLYLIHWPAN 117
Query: 495 -AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 671
F +D N +TWR M D G ++IG+SNF I ++ + P+ QI
Sbjct: 118 EKQFGDDAAKINA---ETWRAMEDLYNEGKIRAIGVSNFMPHHIAELMKTAKVAPAVDQI 174
Query: 672 ELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKT 851
E++ E+ K+ + ++I+V A+ P G A+ P ++ IA KY KT
Sbjct: 175 EVHPGWPHTEVVKYLQAHNILVEAWAPLGG---QGAKVLTNP------TMIQIADKYQKT 225
Query: 852 VPQVALRF 875
QV LR+
Sbjct: 226 PAQVCLRW 233
>UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core
eudicotyledons|Rep: Aldose reductase-like protein -
Arabidopsis thaliana (Mouse-ear cress)
Length = 316
Score = 140 bits (338), Expect = 6e-32
Identities = 87/253 (34%), Positives = 139/253 (54%), Gaps = 9/253 (3%)
Frame = +3
Query: 144 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 323
+L G IP++ +GT+ + + T AV A++ GY H DTA YG E+ +G
Sbjct: 7 RLRCGETIPLLGMGTYCPQKDR-------ESTISAVHQAIKIGYRHFDTAKIYGSEEALG 59
Query: 324 RALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 500
AL + S G ++R+ +F+T+KLW+S H I AL ++L+ + L+Y+D YL+HWPI +
Sbjct: 60 TALGQAISYGTVQRDDLFVTSKLWSSDHH--DPISALIQTLKTMGLDYLDNYLVHWPIKL 117
Query: 501 F--------ENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKP 656
+ D ++ +TW+GM ++GL +SIG+SNF+ ++I ++D P
Sbjct: 118 KPGVSEPIPKEDEFEKDLGIEETWQGMERCLEMGLCRSIGVSNFSSKKIFDLLDFASVSP 177
Query: 657 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQ 836
S Q+E++ +Q +L K C EN+I V Y+P G P I+ + IA
Sbjct: 178 SVNQVEMHPLWRQRKLRKVCEENNIHVSGYSPLGG--PGNC--WGSTAVIEHPIIKSIAL 233
Query: 837 KYNKTVPQVALRF 875
K+N T QVALR+
Sbjct: 234 KHNATPAQVALRW 246
>UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose
reductase - Hordeum vulgare (Barley)
Length = 320
Score = 140 bits (338), Expect = 6e-32
Identities = 82/250 (32%), Positives = 136/250 (54%), Gaps = 7/250 (2%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYAL-EAGYTHIDTAYKYGIEDQVG 323
L SG +P V LGTW + +DT +V A+ EAGY H+DTA +YG+E +VG
Sbjct: 18 LKSGHAMPAVGLGTW----------RAGSDTAHSVRTAITEAGYRHVDTAAEYGVEKEVG 67
Query: 324 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 503
+ L G+ R+ +F+T+K+W + E+V PAL +L++L L+Y+DLY IHWP +
Sbjct: 68 KGLKAAMEAGIDRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLK 127
Query: 504 ENDTL------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL 665
+ + + D W+ M + K GL K IG+ N+ ++ R++ S P+
Sbjct: 128 DGAHMPPEAGEVLEFDMEGVWKEMENLVKDGLVKDIGVCNYTVTKLNRLLRSAKIPPAVC 187
Query: 666 QIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYN 845
Q+E++ + ++F+ C+++ I V AY+P G S + A P ++ +A K N
Sbjct: 188 QMEMHPGWKNDKIFEACKKHGIHVTAYSPLG----SSEKNLAHDPVVEK-----VANKLN 238
Query: 846 KTVPQVALRF 875
KT QV +++
Sbjct: 239 KTPGQVLIKW 248
>UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=10; Trichomonas vaginalis|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 312
Score = 139 bits (337), Expect = 7e-32
Identities = 89/253 (35%), Positives = 141/253 (55%), Gaps = 16/253 (6%)
Frame = +3
Query: 165 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALE-AGYTHIDTAYKYGIEDQVGRALTKK 341
IP + GT+L + P + A+ YA+E G HIDTA+ Y ++ +G L +
Sbjct: 3 IPQLGFGTYLANDPA--------KLKAALHYAIEECGVRHIDTAFAYYNQNVIGETLKEI 54
Query: 342 FSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM----FE 506
F++G +KRE +FITTKLW ++H ++ V P L ++L L L YVDL+LIH PIA +
Sbjct: 55 FAKGKIKREDMFITTKLWCTHHRKDLVEPELHENLAQLQLSYVDLFLIHQPIAFKSLPAK 114
Query: 507 NDTLL----------DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKP 656
+ T++ + +D L+T+ M + +K GLT+ IG+SNF+ EQ++RI + KP
Sbjct: 115 DGTMMPKDEKGKIQYEQIDILETYHAMEECQKKGLTRHIGVSNFSIEQLERIWFNCEIKP 174
Query: 657 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQ 836
A Q+E N+ Q L +C ++I +MA+T G P P ++D + +A
Sbjct: 175 YANQVECNIYRQFKPLLSYCESHNIYLMAHTTIG--HPPLKGPFG-TSLLEDPVVKQVAS 231
Query: 837 KYNKTVPQVALRF 875
+ KT Q+ L+F
Sbjct: 232 EAKKTSAQICLKF 244
>UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep:
Aldose reductase - Magnaporthe grisea (Rice blast
fungus) (Pyricularia grisea)
Length = 312
Score = 139 bits (337), Expect = 7e-32
Identities = 80/219 (36%), Positives = 127/219 (57%), Gaps = 14/219 (6%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 326
L++G IP LGTW G KG + ++AV+ A+++GY ID AY YG E++VG+
Sbjct: 8 LNTGAKIPAFGLGTWQGD--KGVI-------KEAVLTAIKSGYRLIDGAYVYGNEEEVGQ 58
Query: 327 ALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 503
+ + S G+ KRE +F+ +K W +Y R ++ L +SL+ L L+YVDLYL+HWPI M
Sbjct: 59 GIREAISSGIVKREDLFVVSKCWATYTTRCEL--GLDQSLKLLGLDYVDLYLVHWPILMN 116
Query: 504 E--NDT-----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSG 644
ND ++ + +DTW+ M G TK++G+SN+++ +++++
Sbjct: 117 PEGNDEKFPKHADGSRDIIHTHNHVDTWKLMEKLPATGKTKAVGVSNYSKAWLEQLLPHA 176
Query: 645 LEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 761
P+ Q+E + L Q EL FC+E I +MAY+P GS
Sbjct: 177 TTVPAVNQVENHPQLPQQELVDFCKEKGIHIMAYSPLGS 215
>UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;
Corynebacterineae|Rep: 2,5-didehydrogluconate reductase
- Mycobacterium sp. (strain KMS)
Length = 283
Score = 138 bits (335), Expect = 1e-31
Identities = 95/248 (38%), Positives = 133/248 (53%)
Frame = +3
Query: 132 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 311
+P++ L+ G +IPV+ LG G++ + + E++V ALEAGY IDTA YG E
Sbjct: 11 IPSVSLNDGHSIPVLGLGV-------GELSEA--EAERSVAAALEAGYRLIDTAAVYGNE 61
Query: 312 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 491
VGRA+ + G+ RE I++TTKL + A R SLE L L+YVDLYLIHWP
Sbjct: 62 AAVGRAVN---ASGIPREEIYVTTKLAVADQGFGTSQDAARASLERLGLDYVDLYLIHWP 118
Query: 492 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 671
D+ ++D+W G++ AK+ G+ +SIG+ NFN E + IID P+ QI
Sbjct: 119 AG--------DHGKYIDSWGGLMKAKQDGVARSIGVCNFNAEHLSNIIDLSFFTPAINQI 170
Query: 672 ELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKT 851
EL+ L Q EL + IV AY P G +D + G+AQ + KT
Sbjct: 171 ELHPLLNQAELREVNAGYGIVTEAYGPLG-----------VGRLLDHAAVTGVAQAHGKT 219
Query: 852 VPQVALRF 875
QV LR+
Sbjct: 220 PAQVLLRW 227
>UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32;
Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis
thaliana (Mouse-ear cress)
Length = 315
Score = 138 bits (334), Expect = 2e-31
Identities = 87/251 (34%), Positives = 136/251 (54%), Gaps = 7/251 (2%)
Frame = +3
Query: 144 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 323
+L++G P V LGTW G V AV A++ GY HID A YG E ++G
Sbjct: 9 KLNTGAKFPSVGLGTW--QASPGLV-------GDAVAAAVKIGYRHIDCAQIYGNEKEIG 59
Query: 324 RALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 500
L K F + + KRE +FIT+KLW + H+ + V AL ++L++L LEYVDLYLIHWP +
Sbjct: 60 AVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARI 119
Query: 501 ------FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 662
+ + LL VD TW+ M G ++IG+SNF+ +++ +++ P+
Sbjct: 120 KKGSVGIKPENLLP-VDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAV 178
Query: 663 LQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKY 842
Q+E + + +Q +L +FC+ + + AY+P G S + + L +A+K
Sbjct: 179 NQVECHPSWRQTKLQEFCKSKGVHLSAYSPLG----SPGTTWLKSDVLKNPILNMVAEKL 234
Query: 843 NKTVPQVALRF 875
K+ QVALR+
Sbjct: 235 GKSPAQVALRW 245
>UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein;
n=4; Oryza sativa|Rep: OSIGBa0136O08-OSIGBa0153H12.9
protein - Oryza sativa (Rice)
Length = 337
Score = 138 bits (334), Expect = 2e-31
Identities = 89/266 (33%), Positives = 136/266 (51%), Gaps = 13/266 (4%)
Frame = +3
Query: 117 SADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAY 296
+A VP + L+SG +PV+ GT P D + +A+ GY H+DTA
Sbjct: 15 AAATAVPCVTLNSGHAMPVLGFGTGSSTPPA--------DLAATIAHAVRLGYRHLDTAA 66
Query: 297 KYGIEDQVGRALTKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVD 470
YG E VG A+ + G R +F+TTKL + +V+ ALR+SL L L+YVD
Sbjct: 67 VYGTEGAVGAAVAEAVRCGAVASRGELFVTTKLSMADAHPPRVVAALRESLSRLGLDYVD 126
Query: 471 LYLIHWPIAMFENDTL-----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQE 617
L+LIHWP+A+ + D L D WRGM + +LGL +SIG+SNF+
Sbjct: 127 LFLIHWPVAIGKKDAAGELTWDDLSRGLVPFDMEGVWRGMEECHRLGLARSIGVSNFSAA 186
Query: 618 QIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPP 797
++ R++ P+ Q+E+N+ +Q ++ + C E +VV AY+P G +
Sbjct: 187 KMSRLLALAAVPPAVNQVEMNVGWRQEKVREVCGEGGVVVAAYSPLG----AHGAHWGSD 242
Query: 798 PRIDDERLVGIAQKYNKTVPQVALRF 875
++ L +A KT+ QVALR+
Sbjct: 243 AVMNSGVLHDVAAARCKTIAQVALRW 268
>UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 700
Score = 138 bits (334), Expect = 2e-31
Identities = 88/257 (34%), Positives = 136/257 (52%), Gaps = 16/257 (6%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 326
L++G IP + GTW K Q T AV +A++ GY HID A+ Y ED V
Sbjct: 14 LANGAQIPKLGFGTW-----KMSKEQAT----PAVAHAIKTGYRHIDCAWAYRNEDAVAA 64
Query: 327 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 506
+ K G+ R +++T+KLWNS+H E V AL SL++L +Y+DLYL+HWP+A
Sbjct: 65 GIKKA---GVPRSQLWLTSKLWNSFHHPEHVEKALDASLKDLGTDYLDLYLMHWPVAFLN 121
Query: 507 N-DTLLDNV---------------DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 638
+ +++ ++ DF+ T+R M + K G ++IG+SNFN + ++D
Sbjct: 122 SKGSMVPSIRSTGGHPVESEDLSRDFMATYRVMEEMVKKGKVRNIGVSNFNIRRTSEVVD 181
Query: 639 SGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
KP Q+E+NL + EL + + + + AY+PFGS Q A ++D
Sbjct: 182 EASIKPVVNQVEVNLGVHNEELRNYAHAHGVTLQAYSPFGS-----NQNVA--KSLEDPV 234
Query: 819 LVGIAQKYNKTVPQVAL 869
+V +AQ+ N T QV L
Sbjct: 235 VVDVAQRNNITPAQVLL 251
>UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 293
Score = 138 bits (333), Expect = 2e-31
Identities = 79/209 (37%), Positives = 115/209 (55%)
Frame = +3
Query: 132 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 311
+P L +++G IP + LG + V DT+ A+ +AL AGY HIDTA YG E
Sbjct: 11 IPDLPMNNGHQIPQLGLGVFQ--------VDNAEDTKNAIKWALAAGYRHIDTAAYYGNE 62
Query: 312 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 491
VG A+ + + R+ IF+T+KLWNS ++ A +++L+ L L+Y+DLYLIHWP
Sbjct: 63 QWVGEAIRES---DVPRDQIFVTSKLWNSVRGYDETQAAFQETLDKLGLDYLDLYLIHWP 119
Query: 492 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 671
+LD+WR M D K G K+IG+SNFNQ Q+ I+ G KP QI
Sbjct: 120 AP-----------GYLDSWRAMEDLYKAGKIKNIGVSNFNQTQMADILAHGTVKPVVDQI 168
Query: 672 ELNLNLQQPELFKFCRENDIVVMAYTPFG 758
E + QQ ++ + I+ A++P G
Sbjct: 169 ETHPYFQQNDMHAYLESQGILHEAWSPLG 197
>UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 -
Trichoderma atroviride (Hypocrea atroviridis)
Length = 327
Score = 136 bits (330), Expect = 5e-31
Identities = 88/262 (33%), Positives = 135/262 (51%), Gaps = 18/262 (6%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
T L++G IP V GT+ KG +T AV AL+ GY H+D A+ Y ED+
Sbjct: 14 TYTLNTGAKIPAVGFGTFANEGAKG-------ETYAAVTKALDVGYRHLDCAWFYLNEDE 66
Query: 318 VGRALTKKFSE--GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 491
VG A+ + + R+ +FI TK+WN HE E V + + S ENL ++Y+DL+L+HWP
Sbjct: 67 VGDAIRDFLARRPDVTRKDLFICTKVWNHLHEPEDVKWSAKNSCENLKVDYIDLFLVHWP 126
Query: 492 IAMFE----------------NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQI 623
IA + N L +N + TWR M + G+ K+IG+SN+ +
Sbjct: 127 IAAEKNADRTVKIGPDGKYVINKALTENPE--PTWRAMEELVDSGIVKAIGVSNWTIPGL 184
Query: 624 QRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPR 803
+++++ KP+ QIE++ L EL +FC +NDI+ AY+P GS P
Sbjct: 185 KQLLEFARIKPAVNQIEIHPFLPNTELVEFCFQNDILPEAYSPLGS---QNQVPTTGERV 241
Query: 804 IDDERLVGIAQKYNKTVPQVAL 869
D+ L +A + ++ QV L
Sbjct: 242 RDNPTLNAVADRRGSSLAQVLL 263
>UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 360
Score = 131 bits (316), Expect(2) = 6e-31
Identities = 81/211 (38%), Positives = 115/211 (54%), Gaps = 2/211 (0%)
Frame = +3
Query: 168 PVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFS 347
P++ GTW V N TE AV YA+E GY ID A YG E VGR + +
Sbjct: 40 PLIGFGTW------NLKVSPENTTE-AVAYAIEIGYRQIDCAAVYGNEVAVGRGIEEGLK 92
Query: 348 E-GLKRESIFITTKLWNSYH-EREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLL 521
GLKRE I++T+KLWN +H E V L ++L++L LEY+DLYLIHWPI N
Sbjct: 93 RAGLKREDIWVTSKLWNDHHGSYENVEKGLNQTLQDLGLEYLDLYLIHWPIGFSSNGA-- 150
Query: 522 DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPE 701
N+D + T++ MI K +IG+SNF+ Q++ ++ +G P Q+EL+ LQQ
Sbjct: 151 KNLDHVQTYKSMISLPK-SRVLNIGVSNFSPLQLKNVVSTG-TIPYMHQMELHPYLQQSA 208
Query: 702 LFKFCRENDIVVMAYTPFGSLFPSKAQPXAP 794
+ I + AY+P G+ P+ +P
Sbjct: 209 WVATHKALGIKMTAYSPLGNTNPTYHSSTSP 239
Score = 26.6 bits (56), Expect(2) = 6e-31
Identities = 14/35 (40%), Positives = 23/35 (65%)
Frame = +3
Query: 771 SKAQPXAPPPRIDDERLVGIAQKYNKTVPQVALRF 875
S ++P APP + + L+ IA++ N T QVAL++
Sbjct: 261 SSSKPKAPP-LLQNPILIDIAEERNCTPAQVALKW 294
>UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto
reductase family 1, member B10, partial; n=1; Macaca
mulatta|Rep: PREDICTED: similar to aldo-keto reductase
family 1, member B10, partial - Macaca mulatta
Length = 275
Score = 136 bits (328), Expect = 9e-31
Identities = 83/221 (37%), Positives = 125/221 (56%), Gaps = 9/221 (4%)
Frame = +3
Query: 240 EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSE-GLKRESIFITTK------LWNS 398
++AV A++AGY HID AY Y E +VG A+ +K E +KRE +FI +K LW +
Sbjct: 49 KEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEQAVKREDLFIVSKVHMAHWLWTT 108
Query: 399 YHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLG 578
+ ER V A K+L++L L Y+D+YLIHWP + L+D G
Sbjct: 109 FFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKAMEELVDE----------------G 152
Query: 579 LTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTP 752
L K++GISNFN QI+++++ GL+ KP Q+E + L Q +L ++C I + AY+P
Sbjct: 153 LVKALGISNFNHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITITAYSP 212
Query: 753 FGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQVALRF 875
GS A+P P +++ ++ IA K+ KT QV +RF
Sbjct: 213 LGSPDRPWAKP-EDPSLLEEPKIKEIAAKHKKTTAQVLIRF 252
>UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae
str. PEST
Length = 310
Score = 135 bits (327), Expect = 1e-30
Identities = 81/226 (35%), Positives = 122/226 (53%), Gaps = 12/226 (5%)
Frame = +3
Query: 234 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSE--GLKRESIFITTKLWNSYHE 407
D ++A+ A++ GY DTA YG E VG A+ +K E L R+ FI +KL SYH
Sbjct: 31 DGKEAIRTAIDVGYRMFDTAVAYGNEAIVGEAIREKIRECNNLTRDDFFIISKLSGSYHR 90
Query: 408 REQVIPALRKSLENLNLEYVDLYLIHWPIAM------FENDTLLDNVDF----LDTWRGM 557
++ V R +L+ L ++YVDLYL+H P+A+ N T L+ +D + W G+
Sbjct: 91 QDLVEKCCRMTLDRLGMDYVDLYLMHTPVALQSEKKCARNGTKLNAIDDSIAPTEAWIGL 150
Query: 558 IDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVV 737
+ GL +SIG+SNFN+ QI ++ P+ QIE ++ Q + KFC++ +I+V
Sbjct: 151 EQCYQEGLCRSIGVSNFNEHQINALLSDASIVPAVNQIECSIGFNQRPMRKFCQQQNILV 210
Query: 738 MAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQVALRF 875
M YTP G P + + RL IA +KT QV+LR+
Sbjct: 211 MGYTPLGK---------QKLPFLQNNRLKEIALSVDKTTAQVSLRY 247
>UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=3; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 309
Score = 135 bits (327), Expect = 1e-30
Identities = 83/252 (32%), Positives = 141/252 (55%), Gaps = 15/252 (5%)
Frame = +3
Query: 165 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF 344
IP + LGT+L P V + E ++GY H+D A Y ++ +G AL++ F
Sbjct: 4 IPSIGLGTFLAEDPAALKAAVHSAIE-------DSGYRHVDCAAYYKNQEIIGEALSEIF 56
Query: 345 SEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--FENDT 515
++G +KRE ++IT+K+WN+ H + ++ ++K+L+ L LEY+DL L+HW A E+D
Sbjct: 57 AKGQVKREEVWITSKVWNTKHRPDLLVKDVKKTLKELKLEYLDLVLVHWACAFQSREDDE 116
Query: 516 LL----------DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI-IDSGLE-KPS 659
L +N+D L+TW+ M + LGL K IG+SNF+ EQ++R+ D G++ +P
Sbjct: 117 YLPRDETGKIITENIDILETWKAMEECYNLGLAKHIGVSNFSIEQLERMRYDPGVKIQPY 176
Query: 660 ALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQK 839
Q+E ++ LQQ + + + + +++YT G + + P + D L +A++
Sbjct: 177 CNQVESHMYLQQQPMLDYLTQRKMYMISYTCLGR---ATLKGPYGYPLLQDPVLNEVAKE 233
Query: 840 YNKTVPQVALRF 875
KT Q LRF
Sbjct: 234 IGKTPAQTNLRF 245
>UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase A - Corynebacterium sp. (strain ATCC 31090)
Length = 278
Score = 135 bits (327), Expect = 1e-30
Identities = 78/211 (36%), Positives = 120/211 (56%)
Frame = +3
Query: 126 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYG 305
+ VP++ L+ G +IP + G + KV DT++AV ALE GY HIDTA YG
Sbjct: 1 MTVPSIVLNDGNSIPQLGYGVF-------KVPPA--DTQRAVEEALEVGYRHIDTAAIYG 51
Query: 306 IEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 485
E+ VG A+ + G+ R+ +FITTKLWN H+ ++ A+ +SL L L+ VDLYL+H
Sbjct: 52 NEEGVGAAIA---ASGIARDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVH 108
Query: 486 WPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL 665
WP +N ++ W MI+ + GLT+SIG+SN ++RI+ + P+
Sbjct: 109 WPTPAADN--------YVHAWEKMIELRAAGLTRSIGVSNHLVPHLERIVAATGVVPAVN 160
Query: 666 QIELNLNLQQPELFKFCRENDIVVMAYTPFG 758
QIEL+ QQ E+ + +D+ + ++ P G
Sbjct: 161 QIELHPAYQQREITDWAAAHDVKIESWGPLG 191
>UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 282
Score = 135 bits (326), Expect = 2e-30
Identities = 90/244 (36%), Positives = 128/244 (52%)
Frame = +3
Query: 144 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 323
QL++G NIP VA GTW P G+ T QAV AL AGY HIDTA Y E VG
Sbjct: 9 QLANGVNIPKVAFGTW--QIPGGEA------TYQAVRAALAAGYRHIDTALAYQNEASVG 60
Query: 324 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 503
+A+ G+ RE IF+TTKL + + +SL+NL L+YVDLYL+H P
Sbjct: 61 QAIR---DSGIPREQIFVTTKLPAETKSYQGALNDFDRSLKNLGLDYVDLYLVHAPWPWG 117
Query: 504 ENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNL 683
+ + D + LD W+ M + G K+IG+SNF ++ I++ P QI+ L
Sbjct: 118 QVGRVYDEAN-LDVWQAMEAIYQSGRAKAIGVSNFAVRDLKNILNQATIPPMVNQIQYYL 176
Query: 684 NLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQV 863
+P++ KF E+ ++V AY+P A +D+ ++ A KY +V Q+
Sbjct: 177 GFTEPKITKFSEEHAMLVEAYSPL-----------ATGGVLDNPQVQAYADKYGVSVAQL 225
Query: 864 ALRF 875
ALRF
Sbjct: 226 ALRF 229
>UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 337
Score = 135 bits (326), Expect = 2e-30
Identities = 91/250 (36%), Positives = 125/250 (50%), Gaps = 8/250 (3%)
Frame = +3
Query: 150 SSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRA 329
++G IP V LGTW RP N+ AV AL AGY H+D A Y E +VG A
Sbjct: 11 ANGLRIPRVGLGTWKA-RP--------NEVRDAVRDALGAGYAHVDCAAAYANESEVGEA 61
Query: 330 LTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 506
L + F G KRE +F+T+KLWN V AL +L +L + Y+DLYLIHWP+A
Sbjct: 62 LREAFERGDAKREDVFVTSKLWNDRRRPRDVREALMTTLNDLGVGYLDLYLIHWPVAWKR 121
Query: 507 NDTLLDNVD--FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEK--PSALQIE 674
L + + + W + GL + IG+SNFN+ Q+ + D K P+ QIE
Sbjct: 122 GTVLQPDAEASIAECWSELERCVADGLVRHIGVSNFNEAQLAALCDDPRTKIQPACNQIE 181
Query: 675 LNLNLQQPELFKFCRENDIVVMAYTPF---GSLFPSKAQPXAPPPRIDDERLVGIAQKYN 845
+ L K+ + + V AY+P G LF ++E LVG+A+KY
Sbjct: 182 SHPLWSNDSLVKYSQSKGLTVTAYSPLAQGGELF-------------ENEILVGLAKKYG 228
Query: 846 KTVPQVALRF 875
T QV LR+
Sbjct: 229 VTPAQVVLRW 238
>UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_302_44328_45269 - Giardia lamblia
ATCC 50803
Length = 313
Score = 134 bits (325), Expect = 2e-30
Identities = 74/197 (37%), Positives = 105/197 (53%), Gaps = 15/197 (7%)
Frame = +3
Query: 240 EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF---SEGLKRESIFITTKLWNSYHER 410
+ AV AL GY HID AY Y E+ +GRA K F S G+KRE ++IT+KLWN H
Sbjct: 20 QTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKREDVWITSKLWNYNHRP 79
Query: 411 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFEND------------TLLDNVDFLDTWRG 554
E V +K++ +L ++Y+DL+L+HWP+A ND +L+ V DTWR
Sbjct: 80 ELVREQCKKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDAEGRAMLEKVPLADTWRA 139
Query: 555 MIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIV 734
M + GL K IG+SN+ + +++ KP QIE++ KFC +N I
Sbjct: 140 MEQLVEEGLVKHIGVSNYTVPLLADLLNYAKIKPLVNQIEIHPWHPNDATVKFCLDNGIG 199
Query: 735 VMAYTPFGSLFPSKAQP 785
V AY+P G + P
Sbjct: 200 VTAYSPMGGSYADPRDP 216
>UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=4; Oligohymenophorea|Rep: Oxidoreductase,
aldo/keto reductase family protein - Tetrahymena
thermophila SB210
Length = 297
Score = 134 bits (325), Expect = 2e-30
Identities = 88/250 (35%), Positives = 132/250 (52%), Gaps = 2/250 (0%)
Frame = +3
Query: 132 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 311
VP L GG+IP + GT+ ++ Q ND V AL+ GYTHIDTA Y E
Sbjct: 13 VPILNFREGGSIPQIGYGTY-------ELRQ--NDCIIGVTEALKIGYTHIDTASVYRNE 63
Query: 312 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 491
+ + + + G+KRE +FIT+K+ EQ A++ L LN++Y+D LIHWP
Sbjct: 64 QDIAKVIHNP-AYGIKREDLFITSKISPGEQGYEQAKKAVQDMLTRLNIKYLDCVLIHWP 122
Query: 492 --IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL 665
+ ND + L+TW+ +I+ +K G+ K IG+SNFN +Q +I+ KP
Sbjct: 123 GVSKLPPNDPKNAQIR-LETWKALIELRKAGVIKHIGVSNFNINHLQHLIEKSEFKPEMN 181
Query: 666 QIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYN 845
Q E++ + +FC++N I+V AY+P + + P I+ +AQKY
Sbjct: 182 QFEIHPLCFNKKTIEFCQKNGILVEAYSPLA----RQHEKVMKHPLINQ-----LAQKYK 232
Query: 846 KTVPQVALRF 875
KTV QV LR+
Sbjct: 233 KTVAQVILRW 242
>UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Exiguobacterium sibiricum 255-15
Length = 274
Score = 134 bits (324), Expect = 3e-30
Identities = 83/211 (39%), Positives = 115/211 (54%)
Frame = +3
Query: 243 QAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVI 422
+AV AL GY IDTA Y E VGRAL G+ RE IF+TTK+WN E+ +
Sbjct: 29 EAVREALRVGYRSIDTAMIYENEAGVGRALK---DSGIPREDIFLTTKVWNKDQGYERTL 85
Query: 423 PALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGIS 602
A SL+ L ++YVDLYLIHWP+ D ++DTWR + + G K+IG+S
Sbjct: 86 AAFETSLQKLGVDYVDLYLIHWPMP--------DEDLYMDTWRALEQLYRDGKAKAIGVS 137
Query: 603 NFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQ 782
NF+ + R+++ G P+ QIEL+ L Q + FC++N IVV A++P K +
Sbjct: 138 NFHIPHLTRVLEEGTVVPAVNQIELHPFLSQEAIRAFCQKNGIVVEAWSPL-----MKGR 192
Query: 783 PXAPPPRIDDERLVGIAQKYNKTVPQVALRF 875
P I D IA ++ KT QV LR+
Sbjct: 193 DALTDPVITD-----IAARHGKTPAQVVLRW 218
>UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium
SCB49|Rep: ARA1 - unidentified eubacterium SCB49
Length = 280
Score = 134 bits (324), Expect = 3e-30
Identities = 83/246 (33%), Positives = 127/246 (51%), Gaps = 2/246 (0%)
Frame = +3
Query: 144 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 323
+L++ NIP + GTW P G+ A+ A++AGY HID A Y E VG
Sbjct: 6 KLNNNINIPAIGFGTW--QTPDGQTAI------NAIKTAIDAGYKHIDAAAIYKNEKGVG 57
Query: 324 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA-- 497
+ + + R+ +F+T+K+WN E + A ++ +L L+Y+DLYLIHWP A
Sbjct: 58 LGIKEA---NIDRKDLFVTSKVWNEQRGYENTLKAFDNTINDLQLDYLDLYLIHWPAAAH 114
Query: 498 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 677
FEN L+N DTW M K G K++G+SNF + + ++ KP+ QIE
Sbjct: 115 QFENWKQLNN----DTWSAMEKLYKDGKIKALGVSNFMEHHLTPLLQHATIKPTVNQIEY 170
Query: 678 NLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVP 857
+ Q + +FC +N+I V ++P G D+E L +A KYNKTV
Sbjct: 171 HPGYMQQDCVQFCNDNNIQVEGWSPLGR-----------GDVFDNEVLKQLAHKYNKTVA 219
Query: 858 QVALRF 875
Q+++R+
Sbjct: 220 QLSIRW 225
>UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2;
Lactobacillus reuteri|Rep: 2,5-didehydrogluconate
reductase - Lactobacillus reuteri F275
Length = 300
Score = 134 bits (323), Expect = 4e-30
Identities = 78/211 (36%), Positives = 122/211 (57%), Gaps = 2/211 (0%)
Frame = +3
Query: 135 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 314
P ++L++G IP + LG W K + + T+Q V A+ Y IDTA +YG E
Sbjct: 11 PKIKLNNGHLIPQLGLGVW-----KASLAE----TQQMVKEAIMNDYVLIDTAKQYGNEA 61
Query: 315 QVGRALTKKF-SEGLKRESIFITTKLWNSYH-EREQVIPALRKSLENLNLEYVDLYLIHW 488
VG+ + F + G KR+SIF+TTK++N + +++ A+ + L+ L YVDL L+HW
Sbjct: 62 AVGQGIQDGFKATGRKRDSIFLTTKIFNGDQGDYDKLRQAVNEQLKKLQTNYVDLLLLHW 121
Query: 489 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 668
P+ N + ++WR + D K G K+IG+ NFN E++ ++D KP+ Q
Sbjct: 122 PV----------NDKYNESWRALEDIYKDGQAKAIGVCNFNVERMTDLLDHAKIKPAINQ 171
Query: 669 IELNLNLQQPELFKFCRENDIVVMAYTPFGS 761
IE N + QP++ KFCRENDI + A++P G+
Sbjct: 172 IEFNPLIHQPKIVKFCRENDIQLEAWSPLGN 202
>UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC
700755|Rep: YvgN - Psychroflexus torquis ATCC 700755
Length = 280
Score = 133 bits (322), Expect = 5e-30
Identities = 87/245 (35%), Positives = 130/245 (53%), Gaps = 2/245 (0%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKG-KVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 323
L+ G IP+V GT+ + +G K +Q + AL GY IDT Y E+ VG
Sbjct: 5 LNDGNRIPIVGFGTYKANEEEGIKSIQKS---------ALTLGYRLIDTVAIYQNEEAVG 55
Query: 324 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI-AM 500
+A+ + G+ RE IF+TTKLW +Q AL +SL L+L Y+DLYLIHWP A+
Sbjct: 56 KAIKAR---GVLREEIFVTTKLWRENLGYKQTRIALDESLRKLDLNYIDLYLIHWPANAI 112
Query: 501 FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELN 680
D N DTWR M + + G KS+G+SNF E ++ + + PS QIE +
Sbjct: 113 NYKDWQKTNA---DTWRAMEELQAEGKIKSLGVSNFWPEHLEALFQTAKVSPSVNQIEFH 169
Query: 681 LNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQ 860
QP++ +FC+ + I V +++P A ++ L+G+++KY K+V Q
Sbjct: 170 PGYWQPQVTEFCKNHGIAVESWSPL-----------ARGKVFGNDLLIGLSKKYQKSVSQ 218
Query: 861 VALRF 875
V LR+
Sbjct: 219 VCLRW 223
>UniRef50_P22045 Cluster: Probable reductase; n=101; cellular
organisms|Rep: Probable reductase - Leishmania major
Length = 284
Score = 133 bits (322), Expect = 5e-30
Identities = 87/243 (35%), Positives = 123/243 (50%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 326
LS+G +P LG W P G+V TE AV +AL AGY HIDTA Y E+ VG
Sbjct: 11 LSNGVKMPQFGLGVW--QSPAGEV------TENAVNWALCAGYRHIDTAAIYKNEESVGA 62
Query: 327 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 506
L + G+ RE +FITTKLWN+ E + A +S + L ++Y+DLYLIHWP +
Sbjct: 63 GLR---ASGVPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWPRG--K 117
Query: 507 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLN 686
+ + +LD+WR K ++IG+SNF+ ++ ++ P Q+EL+
Sbjct: 118 DILSKEGKKYLDSWRAFEQLYKEKKVRAIGVSNFHIHHLEDVLAMCTVTPMVNQVELHPL 177
Query: 687 LQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQVA 866
Q +L FC I V A++P G + + L I KYNKT QV
Sbjct: 178 NNQADLRAFCDAKQIKVEAWSPLGQ-----------GKLLSNPILSAIGAKYNKTAAQVI 226
Query: 867 LRF 875
LR+
Sbjct: 227 LRW 229
>UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Opitutaceae bacterium TAV2
Length = 347
Score = 133 bits (321), Expect = 6e-30
Identities = 77/224 (34%), Positives = 116/224 (51%), Gaps = 14/224 (6%)
Frame = +3
Query: 132 VPTLQLSSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 308
+P L+SG +P + +GT+ H G+V +V A E GY H D A Y
Sbjct: 16 IPQRTLASGARMPAIGMGTFGSDHAAPGEVAA-------SVYAAAELGYRHFDCAAVYSN 68
Query: 309 EDQVGRALTKKFSE--GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 482
E ++G + + G++RE ++IT+KLWN H VIPA KSL +L L+Y+DLYLI
Sbjct: 69 EREIGATFRRILTSNTGIRREDLWITSKLWNDKHAEADVIPAFEKSLRDLGLDYLDLYLI 128
Query: 483 HWPIAMFE------NDTLLD-----NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQR 629
HWP F + D + +F+ TWR + GL + IG SN ++Q
Sbjct: 129 HWPFPNFHPPGCDVSSRSPDARPYIHAEFMKTWRQLETLHDRGLVRHIGTSNMTIAKLQL 188
Query: 630 IIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 761
++ +P+ ++EL+ + QQP LF + R +IV + Y P GS
Sbjct: 189 LLRDARVRPAVNEMELHPHFQQPALFDYVRVRNIVPVGYCPLGS 232
>UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1;
Propionibacterium freudenreichii subsp. shermanii|Rep:
Putative aldo-keto reductase - Propionibacterium
freudenreichii subsp. shermanii
Length = 280
Score = 132 bits (320), Expect = 9e-30
Identities = 78/208 (37%), Positives = 118/208 (56%)
Frame = +3
Query: 135 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 314
PT++LS G +P++ +GTW KG+ + AV A+E GY +DTA YG E+
Sbjct: 9 PTVELSGGTRMPMLGMGTW---PLKGE------ECRAAVASAIEQGYRLVDTAEAYGNEE 59
Query: 315 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG+A+ + G R IF+TTK +H R+ V AL SLE L L+YVDL+L+HWP+
Sbjct: 60 AVGKAVREA---GPDRAEIFVTTKFSKQWHSRKGVHEALEHSLERLGLDYVDLFLMHWPM 116
Query: 495 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 674
++D +RGM++ K+ GL K+IG+SNF + +I G+ P QI+
Sbjct: 117 P--------GEGSYVDAYRGMVELKEQGLAKAIGVSNFKVHHLDDLITEGM-TPEVNQIQ 167
Query: 675 LNLNLQQPELFKFCRENDIVVMAYTPFG 758
L+ + + E+ F +DIV A++P G
Sbjct: 168 LDPSRPRLEVRDFLDNHDIVTEAWSPLG 195
>UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2;
Actinomycetales|Rep: Putative oxidoreductase -
Streptomyces coelicolor
Length = 277
Score = 132 bits (319), Expect = 1e-29
Identities = 92/249 (36%), Positives = 129/249 (51%), Gaps = 1/249 (0%)
Frame = +3
Query: 132 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQ-AVIYALEAGYTHIDTAYKYGI 308
VP + L++G +P + G W QV +D Q AV ALEAGY IDTA YG
Sbjct: 5 VPPIILNNGVEMPQLGFGVW----------QVPDDDAQTAVALALEAGYRSIDTAAIYGN 54
Query: 309 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 488
E+ GRA+ + GL RE +F+TTKLWNS + + A S+ L LEY+DLYLIHW
Sbjct: 55 EEGTGRAIA---ASGLAREDLFVTTKLWNSDQGYDSTLRAFDTSMAKLGLEYLDLYLIHW 111
Query: 489 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 668
P+ E ++DT++ G ++IG+SNF E ++R+ P+ Q
Sbjct: 112 PMPAKER--------YVDTYKAFEKLLADGRVRAIGVSNFLPEHLERLTAETSVIPAVNQ 163
Query: 669 IELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNK 848
IEL+ +LQQ + E I A++P GS K +D +V IAQK+ +
Sbjct: 164 IELHPHLQQHAAREVHAEQGIATEAWSPLGS---GKG-------ILDIPAIVAIAQKHGR 213
Query: 849 TVPQVALRF 875
T QV LR+
Sbjct: 214 TPAQVVLRW 222
>UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 268
Score = 132 bits (319), Expect = 1e-29
Identities = 84/246 (34%), Positives = 135/246 (54%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
T QLS+G IP++ GT+L + D A+ AL+AGY H+D A+ YG E
Sbjct: 3 TTQLSNGVTIPMLGFGTYLID---------SKDVPAAIKTALDAGYRHLDCAHIYGNEPA 53
Query: 318 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
VG A+ + G+ R +FIT+K+WN+ ++ + A ++L +L L+Y+DLYLIHWP
Sbjct: 54 VGEAIK---ASGIDRSDLFITSKVWNADQGYDKTLAAFDQTLSDLQLDYLDLYLIHWP-- 108
Query: 498 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 677
E+D L LDTWR + + ++IG+SNF+++Q++++ + KP QIE
Sbjct: 109 -NEDDFELT----LDTWRVLETLYQQKKVRAIGVSNFSEDQLKQVFEMATVKPMINQIER 163
Query: 678 NLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVP 857
+ Q +L +F +NDIV Y+P G ++D + +A+KY K+
Sbjct: 164 HPYKVQADLGQFDTDNDIVNEGYSPIGH----------GHLILEDPVITKLAEKYGKSPA 213
Query: 858 QVALRF 875
Q+ LR+
Sbjct: 214 QIVLRW 219
>UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 284
Score = 132 bits (319), Expect = 1e-29
Identities = 88/250 (35%), Positives = 132/250 (52%), Gaps = 3/250 (1%)
Frame = +3
Query: 135 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 314
P ++L++G +PV+ LGTWL +G +A+ A++AGY HIDTAY Y E
Sbjct: 6 PMVKLNNGLEMPVLGLGTWLSKEGEGV---------EAIKAAIDAGYRHIDTAYFYQNEK 56
Query: 315 QVGRALTKKFSEGLK-RESIFITTKLWNSYHEREQVIP-ALRKSLENLNLEYVDLYLIHW 488
+VG A+ K EG+ RE +F+TTK + + + ++P L+ +++Y+D
Sbjct: 57 EVGEAIRAKIEEGVVCREDLFVTTKFID--WDTKNLMPYDADGKLQFSDVDYID------ 108
Query: 489 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 668
TW+ M K G KSIG+SNFN EQI R++ KP Q
Sbjct: 109 ------------------TWKAMEKLLKTGKVKSIGVSNFNSEQITRLLAECEIKPVTNQ 150
Query: 669 IELNLNLQQPELFKFCRENDIVVMAYTPFG-SLFPSKAQPXAPPPRIDDERLVGIAQKYN 845
+E N +L Q +L +FC+ DI + AY+P G + K P P +DD +++ I +KYN
Sbjct: 151 VECNPSLNQRKLTEFCKNLDITLTAYSPLGRPNYYEKDPDNMPKPALDDPKVIEIGKKYN 210
Query: 846 KTVPQVALRF 875
KT QV LR+
Sbjct: 211 KTSGQVILRY 220
>UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8;
Saccharomycetaceae|Rep: Glycerol dehydrogenase -
Zygosaccharomyces rouxii (Candida mogii)
Length = 310
Score = 132 bits (318), Expect = 1e-29
Identities = 87/226 (38%), Positives = 126/226 (55%), Gaps = 19/226 (8%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
TL+L++G IP V LGTW R K N+ +AVI AL+AGY HID A YG E +
Sbjct: 10 TLKLNTGQTIPQVGLGTW---RSK------ENEGYKAVIEALKAGYRHIDGAAVYGNEGE 60
Query: 318 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
VG+A+ G+ R IF+TTKLW ++ Q AL +SL+ L L+YV LYL+HWP+
Sbjct: 61 VGKAIQ---DSGVPRNEIFLTTKLWCTHQRNPQ--EALDQSLQRLGLDYVGLYLVHWPVP 115
Query: 498 M----FENDTLLD---------NVD----FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQ 626
+ ++ L +VD F+ TW M + G TK+IG+SNF+ ++
Sbjct: 116 LRTENIKDGNLFQFAEKPDGSKDVDLEWNFIKTWELMQKLLESGKTKAIGVSNFSVNNLK 175
Query: 627 RIIDSGLEK--PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 758
++ + K P+ Q+E + L Q EL ++C E IV+ AY+P G
Sbjct: 176 DLLAAPTTKVTPAVNQVEFHPLLPQEELIQYCSEKGIVIEAYSPLG 221
>UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 301
Score = 132 bits (318), Expect = 1e-29
Identities = 96/271 (35%), Positives = 140/271 (51%), Gaps = 34/271 (12%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
+ +LSSG ++P V LGTWL +P ++ E AV AL GY HID A Y E++
Sbjct: 6 SFKLSSGYDMPAVGLGTWLS-KP--------HEVENAVETALRLGYRHIDAAACYLNENE 56
Query: 318 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYL------ 479
VG K G+ R+ IFIT+KLWN++H + V A+ K+L++L +Y+DLYL
Sbjct: 57 VGNGWKKS---GVPRDQIFITSKLWNTHHHPDHVEEAVNKTLKDLQTDYLDLYLVFPSLL 113
Query: 480 --------------IHWPIAM-FENDTL-----------LDNVDFLDTWRGMIDAKKLGL 581
IHWP+A N+TL L N+ DTW + G
Sbjct: 114 VLIHDLLSLLTNNKIHWPVAFEHTNETLTPIDPVSKRFRLANIPIADTWAALEKLVDAGK 173
Query: 582 TKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRE--NDIVVMAYTPF 755
+SIG+SNF E+I+ ++ + P+ QIE + LQQP L K+ +E +I+ +AY+P
Sbjct: 174 VRSIGVSNFTIEKIEELLKTARIPPAVNQIEAHPYLQQPALHKYLKEKVTNILSVAYSPL 233
Query: 756 GSLFPSKAQPXAPPPRIDDERLVGIAQKYNK 848
G+ + P +DD + IAQK NK
Sbjct: 234 GNNIYN------APRVVDDPTVKEIAQKLNK 258
>UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep:
Aldehyde reductase - Leptospira interrogans
Length = 278
Score = 131 bits (317), Expect = 2e-29
Identities = 82/246 (33%), Positives = 135/246 (54%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
T+ L++G ++P++ LG W GK + ++AV+ ALEAGY HIDTA Y E
Sbjct: 11 TIMLNNGISMPILGLGVW--KTKSGK------ECKEAVLNALEAGYRHIDTARIYDNEVD 62
Query: 318 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
VG+A+ + G+ R+ IFITTKLWN+ ++ AL SL+ L +++VDLYLIH+P+
Sbjct: 63 VGQAIRES---GIPRKEIFITTKLWNADQGSDKTRKALENSLDRLGIDFVDLYLIHFPVT 119
Query: 498 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 677
+D+W+ + L K+IG+SN+ + ++ + P+ Q+E
Sbjct: 120 SKR----------MDSWKELEKLYHDKLCKAIGVSNYTIIHLTELLKNSQITPAVNQVEF 169
Query: 678 NLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVP 857
+ L Q L ++C+++ I + AY+P A +I+D + IAQKY+KT
Sbjct: 170 HPFLNQIHLLEYCKKHKIQLEAYSPL-----------AHGQKIEDPTIAKIAQKYDKTPA 218
Query: 858 QVALRF 875
Q+ +R+
Sbjct: 219 QILIRW 224
>UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Staphylococcus|Rep: Oxidoreductase,
aldo/keto reductase family - Staphylococcus epidermidis
(strain ATCC 35984 / RP62A)
Length = 279
Score = 131 bits (317), Expect = 2e-29
Identities = 87/243 (35%), Positives = 132/243 (54%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 326
L++G +P V LG + K+ E+ V AL+AGY DTAY YG E +G
Sbjct: 8 LNNGYPMPAVGLGVY-------KIAD--EQMEEVVRTALDAGYRAFDTAYFYGNEKALGS 58
Query: 327 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 506
AL K S ++R+ +FIT+KLWN Y +Q I KSL+NL L+Y+DL+LIHWP E
Sbjct: 59 AL--KHSN-VERDELFITSKLWNDYQGYDQTIEYFNKSLDNLGLDYLDLFLIHWPC---E 112
Query: 507 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLN 686
ND L ++++++ + + G K+IG+ NF +++++ P QIEL+
Sbjct: 113 NDQL-----YIESYKALEHLYEEGKIKAIGVCNFKIHHLEKLMKETKITPQVNQIELHPY 167
Query: 687 LQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQVA 866
Q ++ FC E+DI V A+ P L +K +DD + IA +Y+KT Q+
Sbjct: 168 FNQQDVQDFCDEHDIKVTAWMP---LMRNKG-------LLDDPVITDIAHRYDKTPAQIV 217
Query: 867 LRF 875
LR+
Sbjct: 218 LRW 220
>UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2;
Schizosaccharomyces pombe|Rep: Probable oxidoreductase
C26F1.07 - Schizosaccharomyces pombe (Fission yeast)
Length = 321
Score = 131 bits (316), Expect = 3e-29
Identities = 79/215 (36%), Positives = 117/215 (54%), Gaps = 10/215 (4%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 326
L+ G IP + LGTW N T+ AV AL+ GY HID A YG ED+VG
Sbjct: 18 LADGSKIPGLGLGTWRSE---------PNQTKNAVKTALQYGYRHIDAAAIYGNEDEVGD 68
Query: 327 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM-- 500
+ + G+ R+ I++T+KLW + H E V AL K+L++L L+Y+D YLIHWP++
Sbjct: 69 GIKES---GVPRKDIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKT 125
Query: 501 ----FEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKP 656
F D + + +TW+ M + G + IG+SNFN ++RI+ KP
Sbjct: 126 GEDKFPKDKDGNLIYEKNPIEETWKAMEKLLETGKVRHIGLSNFNDTNLERILKVAKVKP 185
Query: 657 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 761
+ Q+EL+ L Q E + ++ I V AY+PFG+
Sbjct: 186 AVHQMELHPFLPQTEFVEKHKKLGIHVTAYSPFGN 220
>UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Yersinia pestis
Length = 277
Score = 130 bits (313), Expect = 6e-29
Identities = 89/247 (36%), Positives = 127/247 (51%)
Frame = +3
Query: 135 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 314
P ++L G +P + LG W +TE AV ALE GY IDTA Y E+
Sbjct: 5 PLIKLYDGRLMPQLGLGVWQAS---------IQETELAVSKALEVGYRSIDTAAIYKNEE 55
Query: 315 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG+AL + + R+ +FITTKLWN Q AL SL+ L L+YVDLYLIHWP
Sbjct: 56 GVGKALK---AAAVARDELFITTKLWNDDQHNPQ--QALETSLQKLQLDYVDLYLIHWP- 109
Query: 495 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 674
D D+ ++ WR ++ K+ GL +SIG+ NF+ +QR+ID P+ QIE
Sbjct: 110 -----DPKQDH--YVSAWRELVTLKEQGLIRSIGVCNFHIPHLQRLIDETGIAPTVNQIE 162
Query: 675 LNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTV 854
L+ LQQ +L + + I +++P D E + +AQ+YNKT
Sbjct: 163 LHPLLQQRQLHAWNATHHIATESWSPLAQ---------GGKGVFDQEIIRKLAQQYNKTP 213
Query: 855 PQVALRF 875
Q+ +R+
Sbjct: 214 AQIVIRW 220
>UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus
djamor|Rep: Reductase AKOR2 - Pleurotus djamor
Length = 306
Score = 129 bits (312), Expect = 8e-29
Identities = 77/221 (34%), Positives = 123/221 (55%), Gaps = 13/221 (5%)
Frame = +3
Query: 135 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 314
P + L++G +P +ALG W G + + ++ + AL++GY HIDTA Y E
Sbjct: 5 PPIVLNTGARMPALALGGWAGLTEEERT-----QAKEWFLTALKSGYRHIDTAQIYYTEK 59
Query: 315 QVGRALTKKFSEGLKRESIFITTKL-WNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 491
VG A+ + G+ RE +FITTKL WN +H R V + +KSLENL EY+DLYL+H+P
Sbjct: 60 SVGNAIRES---GIPREELFITTKLPWN-HHSR--VAESFQKSLENLGTEYIDLYLVHFP 113
Query: 492 IAMFENDT------------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII 635
+F ++T ++++ D W + G K+IG+SN++ + ++ ++
Sbjct: 114 QRVFYDETTDFPRNPDGSIKVVNSPTLNDVWADVETLLDTGKVKAIGVSNYSIKTLEELL 173
Query: 636 DSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 758
+ P+ Q+EL+ L Q +L +C+E I V AYTP G
Sbjct: 174 KTAKVVPAVNQVELHPFLAQSKLLAYCKEKGIAVTAYTPTG 214
>UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4;
Catarrhini|Rep: Isoform 2 of Q96JD6 - Homo sapiens
(Human)
Length = 263
Score = 94.7 bits (225), Expect(2) = 1e-28
Identities = 52/113 (46%), Positives = 68/113 (60%), Gaps = 1/113 (0%)
Frame = +3
Query: 159 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 338
G+IP V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 339 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
K EG ++RE +FI TKLW + H++ V A RKSL+ L L Y+DLYLIHWP+
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105
Score = 55.6 bits (128), Expect(2) = 1e-28
Identities = 28/65 (43%), Positives = 40/65 (61%), Gaps = 2/65 (3%)
Frame = +3
Query: 507 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIELN 680
N + + DFLDTW M D GL K+IG+SNFN EQ++R+++ GL KP QI +
Sbjct: 139 NMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQILIR 198
Query: 681 LNLQQ 695
+Q+
Sbjct: 199 FQIQR 203
>UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep:
Aldehyde reductase - Acidobacteria bacterium (strain
Ellin345)
Length = 313
Score = 128 bits (310), Expect = 1e-28
Identities = 80/249 (32%), Positives = 130/249 (52%), Gaps = 12/249 (4%)
Frame = +3
Query: 159 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 338
G+IP + GT + + T D AL AG+ H D A +Y E +VG AL
Sbjct: 18 GHIPALGFGTLIAD--PALTITATRD-------ALAAGFRHFDCAERYRNEREVGEALRA 68
Query: 339 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM----- 500
+ G + RE IF+TTKLWN+ H E+V PA SL+ L L+Y+DLYLIH P A
Sbjct: 69 GRAAGNIAREEIFVTTKLWNTNHRPERVEPAFEASLDRLGLDYLDLYLIHTPFAFQPGDE 128
Query: 501 ----FENDTLL--DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 662
+N +++ + V +TW + + G ++IG+S+ + +++ I ++ KP+
Sbjct: 129 QDPRDQNGSVIYDEGVTLRETWSALENLVDRGRCRAIGLSDISMDRLAPIYEAARIKPAV 188
Query: 663 LQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKY 842
+Q+E + L + EL +FC+ N IV++A+ P G P ++D + ++++
Sbjct: 189 VQVESHPYLPETELLEFCKRNGIVLLAFAPLGH--------GMRPGLLEDPVITSVSERV 240
Query: 843 NKTVPQVAL 869
KT QV L
Sbjct: 241 GKTAAQVLL 249
>UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep:
Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 128 bits (309), Expect = 2e-28
Identities = 83/251 (33%), Positives = 133/251 (52%), Gaps = 1/251 (0%)
Frame = +3
Query: 126 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYAL-EAGYTHIDTAYKY 302
L P + L +G NIP++ LGT H + +AV+YAL E G HIDTA +Y
Sbjct: 11 LSCPAVPLHNGLNIPILGLGT--SH--------YGGYSHEAVLYALQECGIRHIDTAKRY 60
Query: 303 GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 482
G E+ +G+A+T+ G++RE +++TTKLW + + A R S L ++Y+DLYL+
Sbjct: 61 GCEEALGKAVTES---GVQREELWVTTKLWPGDYGYQSTKQACRDSRARLGVDYLDLYLM 117
Query: 483 HWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 662
HWP +M + L+TWR + + GL ++IG+SNF + + DSG P
Sbjct: 118 HWPDSMVPGRS--SQEVRLETWRALEELYDEGLCRAIGVSNFLIPHLNELKDSGGIVPHV 175
Query: 663 LQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKY 842
Q+E + Q +L + CR+ +IV Y P +K Q P ++ +A+KY
Sbjct: 176 NQVEFHPFQQPMKLVEHCRKENIVFEGYCPL-----AKGQALTHP------HILELAKKY 224
Query: 843 NKTVPQVALRF 875
++ Q+ +R+
Sbjct: 225 GRSASQICIRW 235
>UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Photorhabdus luminescens subsp. laumondii
Length = 292
Score = 128 bits (309), Expect = 2e-28
Identities = 89/247 (36%), Positives = 129/247 (52%)
Frame = +3
Query: 135 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 314
P ++L+ G ++P + LG+W Q +T A AL+ GY IDTA Y E
Sbjct: 5 PIIRLADGNHMPQLGLGSWASDD------QQIAETIHA---ALDIGYRAIDTAAIYNNEK 55
Query: 315 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG AL + + RE IF+TTKLWN H + AL +SLE L L+YVDLYLIHWP
Sbjct: 56 GVGNALQET---DIPREDIFVTTKLWNDRHLDARA--ALTESLEKLQLDYVDLYLIHWPA 110
Query: 495 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 674
+ ++ W+ +I+ +K GL +SIG+SNF E IQR+I+ P QIE
Sbjct: 111 PPQDQ--------YVGAWQQLIELQKEGLIRSIGVSNFQPEHIQRLINETGVHPVINQIE 162
Query: 675 LNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTV 854
L+ LQQ +L + ++IV +++P D++ + + QKY KT
Sbjct: 163 LHPLLQQRQLHAWNATHNIVTESWSPLAQ---------GGENVFDNQLVQHLTQKYGKTP 213
Query: 855 PQVALRF 875
QV +R+
Sbjct: 214 AQVVIRW 220
>UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4;
Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia
sp. (strain CCS1)
Length = 276
Score = 128 bits (309), Expect = 2e-28
Identities = 78/218 (35%), Positives = 114/218 (52%), Gaps = 1/218 (0%)
Frame = +3
Query: 135 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTE-QAVIYALEAGYTHIDTAYKYGIE 311
P ++ G IP V G W QV D + V A+E GY ID AY Y E
Sbjct: 5 PVIKFHDGAQIPQVGFGIW----------QVPQDIAGETVRSAIEIGYRMIDGAYLYMNE 54
Query: 312 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 491
+G L + GL R+ +F+TTK+WN+ + ++ +SL+ + +E +DL LIHWP
Sbjct: 55 AGLGEGLR---ASGLPRDEVFVTTKVWNNEQGAAKARASVERSLKTIGVEQLDLVLIHWP 111
Query: 492 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 671
+ D +L+TW+ D + GL +SIG SNFN + ++RII E P QI
Sbjct: 112 VP--SQDL------YLETWKAFQDMRDEGLMRSIGTSNFNADHLERIIAETGEAPVLNQI 163
Query: 672 ELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQP 785
ELN LQQPE+ + + +V A+TP G+ +A+P
Sbjct: 164 ELNPMLQQPEMRAVHKAHGVVTQAWTPLGNARSFEAEP 201
>UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr1 scaffold_22, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 360
Score = 128 bits (309), Expect = 2e-28
Identities = 79/215 (36%), Positives = 123/215 (57%), Gaps = 11/215 (5%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 326
L++ IP + LGTW G + V +AV AL GY ID A+ YG E +VG
Sbjct: 14 LNTKAKIPAIGLGTW----QSGGDLCV-----EAVKRALSEGYRQIDCAHLYGNEVEVGE 64
Query: 327 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP-IAMF 503
AL + F+ LKRE +F+T+KL+ + + ++ ++R SL+NL + Y+DLYL+HWP I F
Sbjct: 65 ALAEAFNGSLKREDVFLTSKLYCTMNSLNKIENSVRVSLKNLGVTYLDLYLMHWPDITAF 124
Query: 504 ------ENDTLLDNVDFLD----TWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEK 653
+++ D+ FL+ W+ M +LGL ++IG+SNF +QI+ ++
Sbjct: 125 GDATDPPSNSGNDHRQFLNRLKKAWKAMEGLIELGLVRAIGVSNFGVQQIKELLKFAKIV 184
Query: 654 PSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 758
P+ Q++L+ +Q EL KFC+ I V A+TP G
Sbjct: 185 PAVNQVKLHPFWRQDELVKFCQSKGIHVSAHTPLG 219
>UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5;
Saccharomycetales|Rep: D-arabinose dehydrogenase -
Pichia stipitis (Yeast)
Length = 326
Score = 127 bits (307), Expect = 3e-28
Identities = 80/226 (35%), Positives = 127/226 (56%), Gaps = 21/226 (9%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 326
LS+G IP + LGT P ++ ++ VI A++AGY HIDTA+ YG E+ +G+
Sbjct: 12 LSNGKTIPALGLGTVPPEDP--------HELKEQVITAVKAGYRHIDTAWYYGTEEYIGQ 63
Query: 327 ALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 503
AL + F EG+ KRE +FITTK+W S+ + +L KSL +L L+YVDL+L HWP+ +
Sbjct: 64 ALKQLFEEGIVKREDLFITTKVWPSFWRNPE--KSLDKSLADLGLDYVDLFLQHWPVVLH 121
Query: 504 --EN----------------DTLLDNVDFLDTWRGMID-AKKLGLTKSIGISNFNQEQIQ 626
EN D + + ++D + + D KSIG+SN++ +++
Sbjct: 122 GDENGLPPQPRDKDGKLIYDDDPVSGIKYIDAYHSLEDIMDNTSKVKSIGVSNYSIPKLR 181
Query: 627 RIIDS-GLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 761
+++ + KP QIE + L Q +L K+C +N + + AY+P GS
Sbjct: 182 KLLAAVRKHKPVVNQIEYHPLLPQQDLVKYCYDNGVHISAYSPVGS 227
>UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1;
Lactobacillus acidophilus|Rep: Reductase-dehydrogenase -
Lactobacillus acidophilus
Length = 271
Score = 127 bits (306), Expect = 4e-28
Identities = 84/246 (34%), Positives = 129/246 (52%), Gaps = 3/246 (1%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVI-YALEAGYTHIDTAYKYGIEDQVG 323
L++G IP + LGTWL + ND V+ A+ GY DTA YG E VG
Sbjct: 9 LNNGEKIPQIQLGTWL----------INNDEVNKVVRQAVNIGYRGFDTAKDYGNESGVG 58
Query: 324 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 503
+ + ++ ++R IF+TTKL + + E A+ +L+ LEY+DL LIH P
Sbjct: 59 KGI---WNSDIERSDIFLTTKLPTAVKDYEGTKKAIDAALDKFGLEYIDLLLIHSPQPWI 115
Query: 504 ENDTLLDN--VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 677
E + D L+ WR M +A K G +SIG+SNF QE I+ I+++G P+ QIE+
Sbjct: 116 EVNRTNDRHFKGNLENWRAMEEAVKAGKVRSIGVSNFLQEDIENIVNNGTITPAVNQIEV 175
Query: 678 NLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVP 857
++ EL +C++ I + AY+P L K ++D++++ A+KYN T
Sbjct: 176 HIGKVPVELMDYCKKLGIKIEAYSP---LSHGKL--------LNDDQIIAYAKKYNVTPA 224
Query: 858 QVALRF 875
Q+ L F
Sbjct: 225 QLMLAF 230
>UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 292
Score = 127 bits (306), Expect = 4e-28
Identities = 76/208 (36%), Positives = 114/208 (54%), Gaps = 1/208 (0%)
Frame = +3
Query: 132 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 311
+PT L +G IPV+ GT+ KV DT AV ALE GY HIDTA YG E
Sbjct: 16 IPTFMLPTGSPIPVLGFGTY-------KVAP--EDTYDAVSRALEVGYRHIDTAQMYGNE 66
Query: 312 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 491
+VG AL + G+ RE +FITTK+ NS HE ++ ++R+SLE+L +YVDL L+HWP
Sbjct: 67 AEVGAALE---ASGIAREDLFITTKVDNSNHEPDRAAASIRRSLEDLRTDYVDLLLVHWP 123
Query: 492 I-AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 668
+ ++ D L W + DA G ++IG+SN+ +E ++ + + P LQ
Sbjct: 124 LPTLYGGDVAL-------PWPALEDAFNAGGARAIGLSNYEREHVEAVREVATVAPHVLQ 176
Query: 669 IELNLNLQQPELFKFCRENDIVVMAYTP 752
+E + +L + + +V A++P
Sbjct: 177 VESHPFFPNADLRAYAQGLGMVFEAWSP 204
>UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3;
n=39; cellular organisms|Rep: NADPH-dependent aldose
reductase GRE3 - Saccharomyces cerevisiae (Baker's
yeast)
Length = 327
Score = 127 bits (306), Expect = 4e-28
Identities = 94/268 (35%), Positives = 139/268 (51%), Gaps = 25/268 (9%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 326
L++G +P+V LG W + KV + A++ GY D A YG E +VG
Sbjct: 7 LNNGLKMPLVGLGCW---KIDKKVCA------NQIYEAIKLGYRLFDGACDYGNEKEVGE 57
Query: 327 ALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM- 500
+ K SEGL R+ IF+ +KLWN++H + V AL+K+L ++ L+Y+DLY IH+PIA
Sbjct: 58 GIRKAISEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFK 117
Query: 501 ---FEND------TLLD----------NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQI 623
FE T D +V +DT+R + + GL KSIG+SNF I
Sbjct: 118 YVPFEEKYPPGFYTGADDEKKGHITEAHVPIIDTYRALEECVDEGLIKSIGVSNFQGSLI 177
Query: 624 QRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG--SLFPSKAQ-PXAP 794
Q ++ KP ALQIE + L Q L +FC+ +DI V+AY+ FG S Q
Sbjct: 178 QDLLRGCRIKPVALQIEHHPYLTQEHLVEFCKLHDIQVVAYSSFGPQSFIEMDLQLAKTT 237
Query: 795 PPRIDDERLVGIAQKY-NKTVPQVALRF 875
P +++ + ++Q + T QV LR+
Sbjct: 238 PTLFENDVIKKVSQNHPGSTTSQVLLRW 265
>UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus
coagulans 36D1|Rep: Aldo/keto reductase - Bacillus
coagulans 36D1
Length = 273
Score = 126 bits (305), Expect = 6e-28
Identities = 80/246 (32%), Positives = 128/246 (52%), Gaps = 2/246 (0%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
T L +G IP + LGTW P G+ T AV +AL+ GY HIDTAY Y E+
Sbjct: 7 TFVLENGVAIPKIGLGTW--QVPNGET------TYHAVSFALKNGYRHIDTAYAYHNEES 58
Query: 318 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH--WP 491
VG+A+ G+ R IF+T+KL ++ + +++ N LE +DLYLIH WP
Sbjct: 59 VGKAVR---DSGIDRRDIFVTSKLPAEIKSYDKALKTFDETMGNFGLEQLDLYLIHAPWP 115
Query: 492 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 671
+ D +N++ W+ M + + G ++IG+SNF+ ++ ++++ KP QI
Sbjct: 116 WSEKGADYTKENIE---VWKAMEEIYESGRCRAIGVSNFSVSDLKAVMENAKIKPMVNQI 172
Query: 672 ELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKT 851
+ Q ++ FC++N I+V AY+P A +++ + IA KY KT
Sbjct: 173 RYFIGHTQEDVTAFCQDNGILVEAYSPL-----------ATGKILENAEIQKIADKYGKT 221
Query: 852 VPQVAL 869
+PQV +
Sbjct: 222 LPQVCI 227
>UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 295
Score = 126 bits (304), Expect = 7e-28
Identities = 84/247 (34%), Positives = 132/247 (53%), Gaps = 1/247 (0%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
T +L +G +PV LGT+ KVV + + AL+ GY HIDTA Y E Q
Sbjct: 7 TTELCNGSKLPVFGLGTY-------KVVS-KEEMVTFLRTALDLGYRHIDTAIMYENEKQ 58
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
+G AL + + EG KRE +F+ TKL+++ + +V +R+SL+NL Y+DLYL+H+
Sbjct: 59 IGDALQEIYKEGKYKREDLFLVTKLFSN--KNTKVEDQVRQSLQNLQTNYIDLYLLHYAS 116
Query: 495 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 674
+ + L + W + + GL ++IGISNFN + + + KP QIE
Sbjct: 117 SPPTDQFELTHKPVFQVWAEFEELVQKGLIRNIGISNFNVQMLLDLYSYCKIKPVVNQIE 176
Query: 675 LNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTV 854
+N+ QQP L +FC++ ++ V AY P ++ Q +D L ++ KY K+V
Sbjct: 177 VNVYCQQPRLLEFCKKLNLHVTAYCPL-----ARCQNTD-----NDALLTELSTKYKKSV 226
Query: 855 PQVALRF 875
Q+ L+F
Sbjct: 227 CQIMLQF 233
>UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1;
Erythrobacter sp. SD-21|Rep: Putative oxidoreductase
protein - Erythrobacter sp. SD-21
Length = 272
Score = 126 bits (304), Expect = 7e-28
Identities = 78/208 (37%), Positives = 112/208 (53%)
Frame = +3
Query: 135 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 314
PTL L+ G IP + GTW D QAV A++ GY IDTA YG E
Sbjct: 5 PTLNLNDGRQIPQLGFGTWQMEE---------EDAPQAVSTAIDVGYWLIDTAAIYGNEK 55
Query: 315 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG+ + + +S+ IF+ TK+WN ++ + A K LE L E+VD+ LIHWP
Sbjct: 56 GVGKGVGE-WSD------IFLQTKIWNDSQGYDRTLRAAEKCLERLGREHVDMLLIHWPC 108
Query: 495 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 674
E D F+DTW+ +I+ + G KSIG+SNF +E ++RIID P+ QIE
Sbjct: 109 P--EKD------QFVDTWKALIELRDAGKAKSIGVSNFREEDLKRIIDETGVTPALNQIE 160
Query: 675 LNLNLQQPELFKFCRENDIVVMAYTPFG 758
L+ + QQ ++ K + IV +++P G
Sbjct: 161 LHPSFQQRDMRKVHEDLGIVTQSWSPLG 188
>UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 287
Score = 126 bits (303), Expect = 1e-27
Identities = 77/239 (32%), Positives = 125/239 (52%), Gaps = 1/239 (0%)
Frame = +3
Query: 162 NIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKK 341
N+P++ +GTW VQ Q + + GY IDTA Y E ++GR L K
Sbjct: 10 NMPLIGIGTWQ--------VQKEEILRQVIDAGFKEGYRFIDTAQVYNNEAKIGRILEKL 61
Query: 342 F-SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTL 518
+ GLKRE I+IT+KL S ++ ++ +SL NL +EY+DL LIHWP + +++
Sbjct: 62 LPANGLKREDIWITSKLAPSNAGVKKARESIEESLSNLKVEYLDLLLIHWPGSSLKSENP 121
Query: 519 LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQP 698
+ +++W M + G +S+G+SNF ++ + P+ Q+E + + Q
Sbjct: 122 ANKKLRVESWNVMCEMMAEGKLRSVGVSNFEICHLEELKKDSNVVPAVNQVEYHPHFHQD 181
Query: 699 ELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQVALRF 875
+L K+C EN+I AY+ GS P+ + + P I + +AQKYN +P + L F
Sbjct: 182 DLVKYCNENNIHFQAYSSLGS--PTYRKQLSEEPLIKE-----LAQKYNVEIPVLLLGF 233
>UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several
dehydrogenases of different specificities; n=4;
Pezizomycotina|Rep: Similarity: shows similarity to
several dehydrogenases of different specificities -
Aspergillus niger
Length = 381
Score = 125 bits (302), Expect = 1e-27
Identities = 78/223 (34%), Positives = 117/223 (52%), Gaps = 18/223 (8%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 326
L+SG IP + GTW G+V AV AL+AGY H+D A Y + +V
Sbjct: 9 LNSGAQIPQLGFGTW--QSAPGQV-------GDAVYEALKAGYRHLDLATIYQNQREVAE 59
Query: 327 ALTKKFSE--GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 500
+ + + + GLKRE IFIT+KLWNS H+ V AL + L L L+Y+DLYL+HWP++
Sbjct: 60 GIKRAYKDVPGLKREDIFITSKLWNSQHDPAVVEKALDECLAELELDYLDLYLVHWPVSF 119
Query: 501 FENDTLL----------------DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI 632
L D++ +DTW+ M K +++G+SN ++ I
Sbjct: 120 TTGSELFPLVKDSSVEGGDVVINDDISIVDTWKAMTQLPK-SKARTVGVSNHMIPHLEAI 178
Query: 633 IDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 761
I++ P+ QIE + LQ EL ++C++ I V AY+ FG+
Sbjct: 179 INATGVVPAVNQIERHPVLQSNELIEYCQKKGIHVTAYSAFGN 221
>UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4;
Bifidobacterium|Rep: Dehydrogenase or reductase protein
- Bifidobacterium longum
Length = 289
Score = 125 bits (301), Expect = 2e-27
Identities = 77/208 (37%), Positives = 113/208 (54%), Gaps = 1/208 (0%)
Frame = +3
Query: 132 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 311
VP + L G +IP V LG L +G V V + ALEAGY HID A Y E
Sbjct: 11 VPDIALKDGHSIPQVGLGV-LRIDDEGVVPVVES--------ALEAGYRHIDGAAGYNNE 61
Query: 312 DQVGRALTKK-FSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 488
VGRAL +++G KRE++++TTKL +S + + A SL+ L L+YVD+Y+IHW
Sbjct: 62 AGVGRALAASGYNKGAKRETLWVTTKLRDSQQGYDSALKAFDNSLKLLQLDYVDMYMIHW 121
Query: 489 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 668
P T DTW+ + + G+ +++G+ NF ++R+ + P+ Q
Sbjct: 122 PTPFDWRST--------DTWKAFVKLRDEGMARTLGVCNFMPADLKRLHEETGAWPAVNQ 173
Query: 669 IELNLNLQQPELFKFCRENDIVVMAYTP 752
IEL+ QQ E+ FC+E+ I V AY+P
Sbjct: 174 IELHPTWQQREVVAFCKEHGIAVEAYSP 201
>UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=1;
Arabidopsis thaliana|Rep: Uncharacterized protein
At2g37770.1 - Arabidopsis thaliana (Mouse-ear cress)
Length = 283
Score = 125 bits (301), Expect = 2e-27
Identities = 73/203 (35%), Positives = 114/203 (56%), Gaps = 7/203 (3%)
Frame = +3
Query: 144 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 323
+L++G P V LGTW G V AV A++ GY HID A YG E ++G
Sbjct: 9 KLNTGAKFPSVGLGTW--QASPGLV-------GDAVAAAVKIGYRHIDCAQIYGNEKEIG 59
Query: 324 RALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 500
L K F + + KRE +FIT+KLW + H+ + V AL ++L++L LEYVDLYLIHWP +
Sbjct: 60 AVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARI 119
Query: 501 ------FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 662
+ + LL VD TW+ M G ++IG+SNF+ +++ +++ P+
Sbjct: 120 KKGSVGIKPENLLP-VDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAV 178
Query: 663 LQIELNLNLQQPELFKFCRENDI 731
Q+E + + +Q +L +FC+ +
Sbjct: 179 NQVECHPSWRQTKLQEFCKSKGV 201
>UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7;
cellular organisms|Rep: Prostaglandin f synthase,
putative - Leishmania major
Length = 279
Score = 125 bits (301), Expect = 2e-27
Identities = 76/243 (31%), Positives = 126/243 (51%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 326
LS+G +P + +GTW + +VV + +A+ AGY H+DTA+ Y E VG+
Sbjct: 10 LSNGVQVPQLGIGTWEA-KDGNEVVNIK--------WAVNAGYRHVDTAHYYKNEKGVGQ 60
Query: 327 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 506
+++ G+ R IF+TTKLWN H E + A +S + L +EYVDLYLIHWP
Sbjct: 61 GISEC---GVPRSDIFVTTKLWNYDHGYESALAAFEQSRQALGVEYVDLYLIHWP----- 112
Query: 507 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLN 686
N +++TWR ++ ++IG+SNF + ++ + P Q+E++ +
Sbjct: 113 ----GPNRSYIETWRAFEKLYEMKKVRAIGVSNFEPHHLDDLLANCTVPPMVNQVEMHPH 168
Query: 687 LQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQVA 866
QQ L +C E +I V A+ P G + + +LV +A+K+ ++ QV
Sbjct: 169 FQQKALRAYCAEKNIAVTAWRPLGK-----------GALLTEPQLVELAEKHKRSAAQVI 217
Query: 867 LRF 875
+R+
Sbjct: 218 IRW 220
>UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 275
Score = 124 bits (298), Expect = 4e-27
Identities = 74/213 (34%), Positives = 117/213 (54%)
Frame = +3
Query: 237 TEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQ 416
T+QAV++ALE GY IDTA Y E +VG AL + + R +++ TK++++ H E+
Sbjct: 30 TKQAVLWALENGYRMIDTAASYNNEKRVGEALRES---AVPRSEVYLVTKVYHTDHGYEK 86
Query: 417 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 596
+ A +SL L ++YVDLYLIH+P+ + +W M + + GLT+SIG
Sbjct: 87 TMKAYDRSLSALGVDYVDLYLIHFPVP----------AGVVGSWEAMAELQGKGLTRSIG 136
Query: 597 ISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSK 776
+SNFN ++ + + P QIE++ LQ EL FCR++ I + AY+P ++
Sbjct: 137 VSNFNIHHLEALQKHSVIPPVVNQIEVHPYLQMEELVDFCRKHSIAIQAYSPL-----TR 191
Query: 777 AQPXAPPPRIDDERLVGIAQKYNKTVPQVALRF 875
+ ++ D L + KY KT QV LR+
Sbjct: 192 GE------KLHDPLLRSLGDKYGKTPAQVLLRW 218
>UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase;
n=2; Parasitella parasitica|Rep:
4-dihydromethyltrisporate dehydrogenase - Parasitella
parasitica
Length = 321
Score = 124 bits (298), Expect = 4e-27
Identities = 80/233 (34%), Positives = 119/233 (51%), Gaps = 19/233 (8%)
Frame = +3
Query: 234 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL-KRESIFITTKLWNSYHER 410
D E + A++ GY D A YG E +VGR + K EGL KRE +FI TKLWN++H +
Sbjct: 29 DAENTIYQAIKIGYRLFDGACDYGNEVEVGRGINKAIKEGLVKREELFIVTKLWNTFHSK 88
Query: 411 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLL-----------DNVDF-----LD 542
+ V A + L++ LEY DLYLIH+PI + D + D ++F +
Sbjct: 89 QHVRTAFDRQLKDWGLEYFDLYLIHFPIPLQYVDPAVSYPPEWYVPHADKLNFERSPIHE 148
Query: 543 TWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRE 722
W M + LT++IG++NFN + I ++ KP+ LQIE++ L Q L K+ +E
Sbjct: 149 CWAEMEKLVQAKLTRNIGVANFNCQAILDLLSYAKIKPAVLQIEIHPLLPQERLVKWVQE 208
Query: 723 NDIVVMAYTPFG--SLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQVALRF 875
I V AY+ FG S + + + IA K+N Q+ LR+
Sbjct: 209 QGIQVTAYSSFGPTSYVDLCESGKTYSSLLANADVKSIANKHNANTGQILLRY 261
>UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep:
Benzil reductase - Bacillus subtilis
Length = 276
Score = 123 bits (297), Expect = 5e-27
Identities = 83/246 (33%), Positives = 127/246 (51%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
T++L +G +P LG + V+ N+ ++V A++ GY IDTA Y E+
Sbjct: 8 TVKLHNGVEMPWFGLGVFK--------VENGNEATESVKAAIKNGYRSIDTAAIYKNEEG 59
Query: 318 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
VG + + G+ RE +FIT+K+WN E + A KSLE L L+Y+DLYLIHWP
Sbjct: 60 VGIGIKES---GVAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWP-- 114
Query: 498 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 677
+ DTWR + K G ++IG+SNF ++ ++ KP Q+E
Sbjct: 115 --------GKDKYKDTWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDAEIKPMVNQVEF 166
Query: 678 NLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVP 857
+ L Q EL +C+ I + A++P + Q +D+E L IA+K+NK+V
Sbjct: 167 HPRLTQKELRDYCKAQGIQLEAWSPL-----MQGQ------LLDNEVLTQIAEKHNKSVA 215
Query: 858 QVALRF 875
QV LR+
Sbjct: 216 QVILRW 221
>UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinomycetales|Rep: 2,5-didehydrogluconate reductase -
Kineococcus radiotolerans SRS30216
Length = 289
Score = 123 bits (297), Expect = 5e-27
Identities = 85/251 (33%), Positives = 128/251 (50%), Gaps = 1/251 (0%)
Frame = +3
Query: 126 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVT-NDTEQAVIYALEAGYTHIDTAYKY 302
+ VPT+ L+ G IP + G V Q+ DT QAV AL+ GY HIDTA Y
Sbjct: 10 MTVPTILLNDGREIPQLGFG----------VFQIEPGDTAQAVKTALDLGYRHIDTAQMY 59
Query: 303 GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 482
G E +V + + G+ R+ I++T+KL N +HE + A+ S+E L +DLYLI
Sbjct: 60 GNEAEVAQGIA---DSGVPRDEIWVTSKLNNGFHEPDAARKAVDDSVEKLRGP-IDLYLI 115
Query: 483 HWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 662
HWP+ TL DF+ TW+ + +A+ G +SIG+SNF +QR+ P+
Sbjct: 116 HWPLP-----TLYGG-DFVSTWKVLEEARAAGKLRSIGVSNFQVNHLQRLAQEATVVPAV 169
Query: 663 LQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKY 842
QIE++ E+ + C E+ I V A++P A +DD + +A +
Sbjct: 170 NQIEVHPYFGNEEVRRHCGEHQIGVEAWSPI-----------AQGKVLDDPTVTAVANRL 218
Query: 843 NKTVPQVALRF 875
K+ QV LR+
Sbjct: 219 GKSPAQVVLRW 229
>UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=2; Tetrahymena thermophila SB210|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 332
Score = 123 bits (297), Expect = 5e-27
Identities = 72/215 (33%), Positives = 121/215 (56%), Gaps = 1/215 (0%)
Frame = +3
Query: 144 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 323
+L++G +P+V LGT+L + + ++TN + AL+AGY HIDTA Y E +G
Sbjct: 9 KLNNGQIMPLVGLGTYLLNSKE----EMTN----LLRTALDAGYRHIDTAVNYQNEAMIG 60
Query: 324 RALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 500
+L F EG R+ +FI +K++ + + ++ +++KSL+ L L+YVDLY +H+P+
Sbjct: 61 ESLKTIFKEGKYSRKDLFIVSKVFPN--KGINMLESVKKSLKELQLDYVDLYYLHFPLGF 118
Query: 501 FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELN 680
++ W + +A +LGL KSIG+SNFN + ++ KP + Q+E++
Sbjct: 119 LSEKEEFVHLPVHVAWAQLEEAHRLGLAKSIGVSNFNVMALADLLSYAKVKPVSNQVEVS 178
Query: 681 LNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQP 785
+ +QQ L KFC+ I V AY P ++ P
Sbjct: 179 VFIQQKNLIKFCQRFGIHVTAYAPLAKYTDVESNP 213
>UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 323
Score = 123 bits (296), Expect = 7e-27
Identities = 79/251 (31%), Positives = 136/251 (54%), Gaps = 7/251 (2%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY-ALEAGYTHIDTAYKYGIEDQ 317
+QL++G +P++ LGT +P V +VT + ++ AL+ GY + DTA +Y E +
Sbjct: 15 VQLNNGYKMPLLGLGT----QPYDIVTRVTVEEMTTLLSNALDFGYRNFDTAKQYRNEVE 70
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP- 491
+G+A F +G KRE +FITTKL+ + +++ ++ SL+ L Y+DLYLI W
Sbjct: 71 IGQAFQNIFQQGKYKREDVFITTKLF-PFKIEKKIKEVVQNSLDQLQTSYIDLYLIQWSF 129
Query: 492 ---IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 662
+ F+ +++ + WR + + +LG+ +SIG++NFN + + ++ KP
Sbjct: 130 TPVLTNFDGSVAVNHRPIHEVWRELEECVELGMIRSIGVANFNCQMVLDLLSYAKIKPVV 189
Query: 663 LQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLV-GIAQK 839
QIE+ L Q +L F + I +A +P G + P ++ +E + IAQK
Sbjct: 190 NQIEVTPYLPQIDLINFLKRCKIETVAISPLGRAGCFENTPEGMKIKLLEEDIFKQIAQK 249
Query: 840 YNKTVPQVALR 872
+ K+V QV LR
Sbjct: 250 HKKSVVQVILR 260
>UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:
ENSANGP00000029046 - Anopheles gambiae str. PEST
Length = 331
Score = 123 bits (296), Expect = 7e-27
Identities = 89/260 (34%), Positives = 139/260 (53%), Gaps = 14/260 (5%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
T +L++G +IP+ GT+ H + + QV + YALEAGY HIDTA Y E+
Sbjct: 33 TFKLNTGFDIPLAGFGTYQIHGQE-LIYQVLD-------YALEAGYRHIDTAVVYRNEEY 84
Query: 318 VGRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPAL-RKSLENLNLEYVDLYLIHWP 491
+G AL + LKRE IFIT+KL + + E + + RKSL NL +Y+DLYLIHWP
Sbjct: 85 IGTALKTLLPKYNLKREDIFITSKLISQSGKDEAFVEQMVRKSLANLQTDYLDLYLIHWP 144
Query: 492 IA---------MFEND-TLLDNVDF-LDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII- 635
+F T DNV + +W + ++ G +SIG+SN+ + ++ ++
Sbjct: 145 GVSGKCGRWKWLFGMQVTHPDNVKYRAASWNALSKLEREGCLRSIGVSNYTVKHLKEMLA 204
Query: 636 DSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDE 815
D P+ Q+E + QPEL ++CR++ I + AY+ GS ++ + +DE
Sbjct: 205 DCKGIVPAVNQVEWHPYYYQPELLEYCRQHGIFLQAYSSLGSSNTAELR--------EDE 256
Query: 816 RLVGIAQKYNKTVPQVALRF 875
+ +A+ KT QV LR+
Sbjct: 257 TVQSVAKSLQKTPVQVLLRW 276
>UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6;
n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 -
Apis mellifera
Length = 292
Score = 122 bits (295), Expect = 9e-27
Identities = 76/215 (35%), Positives = 118/215 (54%), Gaps = 4/215 (1%)
Frame = +3
Query: 129 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 308
IV + LSSG ++P++ GT+ +Q Q V +L G+ IDTA Y
Sbjct: 4 IVRNVCLSSGYDMPLIGFGTYK--------IQGRELVYQVVDESLNVGFRSIDTAVGYRN 55
Query: 309 EDQVGRALTKKFSE-GLKRESIFITTKLWNSYH-EREQVIPALRKSLENLNLEYVDLYLI 482
E+ +G AL + L+R IFITTKL S + + + + ++KSL+ N Y+DLYLI
Sbjct: 56 EEDIGYALKNLLPKYNLQRSDIFITTKLPPSVNGDPKGIEQCVQKSLKAFNTTYIDLYLI 115
Query: 483 HWPIAMFENDTLLDNVDF-LDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE-KP 656
HWP A +T +N TW ++D KK G +SIG+SNF + +Q ++ + + P
Sbjct: 116 HWPGATRIPETSTNNPSLRAKTWNKLVDLKKQGFIRSIGVSNFTIKHLQELLQNCKDILP 175
Query: 657 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 761
+ Q+EL+ + +Q EL K+C E I + AY+ G+
Sbjct: 176 AVNQVELHPHYRQEELIKYCNEKGIHIQAYSSLGT 210
>UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 -
Mycoplasma gallisepticum
Length = 289
Score = 122 bits (295), Expect = 9e-27
Identities = 80/213 (37%), Positives = 118/213 (55%)
Frame = +3
Query: 237 TEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQ 416
T +AV ALE GY H+D A Y E+Q+ + K S G+ R+ IFIT+K+WN E
Sbjct: 38 TVEAVKTALEVGYRHLDCAEIY--ENQLSVSQGIKLS-GVNRKEIFITSKIWNDDKGYES 94
Query: 417 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 596
A K L++L+LEY+DL LIHWPI D V+ TW+ M + G K+IG
Sbjct: 95 TKKAFHKILKDLDLEYLDLLLIHWPIGKGFKDN-WQEVN-AQTWKAMEEFYLEGKIKAIG 152
Query: 597 ISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSK 776
+SNF I+ + S P Q+E + QPE+ ++C++N+IVV A++PF SK
Sbjct: 153 LSNFLVHHIEALKKSAKILPMVNQLEFHPGYLQPEIVEYCQKNNIVVQAWSPFSQ---SK 209
Query: 777 AQPXAPPPRIDDERLVGIAQKYNKTVPQVALRF 875
++++ LV +A+KY TV Q+ L +
Sbjct: 210 V--------LENKTLVQLAKKYEVTVAQLILNW 234
>UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=3; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 324
Score = 122 bits (294), Expect = 1e-26
Identities = 80/228 (35%), Positives = 128/228 (56%), Gaps = 17/228 (7%)
Frame = +3
Query: 129 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 308
I + +L+ G +IP + LGT G V E+ V A++ GY HIDTA+ YG
Sbjct: 3 ITDSFKLNDGHSIPALGLGT----ASDGNV-------EEVVYAAIKNGYRHIDTAFIYGS 51
Query: 309 EDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 485
E VG+ + + E L KRE++F+TTK+W +++ R V +L SL++L+L+YVDL L+H
Sbjct: 52 EVDVGKGIKRAIDEELVKRENLFVTTKVWPTFYNR--VSESLDISLKDLSLDYVDLLLVH 109
Query: 486 WPIAMF------------ENDTLLDNVDFLDTW---RGMIDAKKL-GLTKSIGISNFNQE 617
WP+++ D + D LD W I+ +KL G TKSIG+SN ++
Sbjct: 110 WPVSLLADSDDPRAIYLVNTDGSVRYSDSLDDWITTYKQIEEEKLSGRTKSIGVSNVSEV 169
Query: 618 QIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 761
++R++D P+ Q E++ L Q + +F ++ I+V A++P GS
Sbjct: 170 YLKRLLDQVKTVPAVNQFEIHPYLPQKKEIEFNEKHGILVTAFSPLGS 217
>UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinobacteria (class)|Rep: 2,5-didehydrogluconate
reductase - Arthrobacter sp. (strain FB24)
Length = 276
Score = 122 bits (293), Expect = 2e-26
Identities = 82/247 (33%), Positives = 126/247 (51%)
Frame = +3
Query: 135 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 314
P ++L+ G IP + LGTW P + AV+ A+E GY HIDTA KYG E
Sbjct: 5 PVIELNDGHRIPQIGLGTW----PLDD-----HQVAAAVVNAVEGGYRHIDTAVKYGNEK 55
Query: 315 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG + S GL R +FITTKL + +++ + L SL+ L L+YVDL LIHWP+
Sbjct: 56 GVGNGIR---SSGLDRSELFITTKLDGEFQGQDRAVAGLDGSLKRLGLDYVDLLLIHWPL 112
Query: 495 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 674
+ +F+ TW+ + G +SIG+SNF ++R++ + P+ QI+
Sbjct: 113 PRRD--------EFISTWKTFERLQADGKVRSIGVSNFKPAHLERLMAACDVVPAVNQIQ 164
Query: 675 LNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTV 854
++ + + + R + IV +Y+P G A ++ L IAQK+ KT
Sbjct: 165 VSPAITRIVDIAYNRRHGIVTESYSPLG----------AGSDLLNAPVLGRIAQKHGKTP 214
Query: 855 PQVALRF 875
Q+ LR+
Sbjct: 215 GQIVLRW 221
>UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 322
Score = 121 bits (292), Expect = 2e-26
Identities = 86/256 (33%), Positives = 135/256 (52%), Gaps = 3/256 (1%)
Frame = +3
Query: 117 SADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTND--TEQAVIYALEAGYTHIDT 290
S ++ ++L++G IP VALG V + ND TE A +A +AGY HID+
Sbjct: 11 SGNISTQRIKLNNGQEIPQVALG----------VYKAPNDGSTENACKWAFDAGYRHIDS 60
Query: 291 AYKYGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 467
A +Y E+ VGRAL + E + R IFIT+KLW++ H++ A+ SL+ LN++Y+
Sbjct: 61 AARYMNEESVGRALAEWTKENNVPRSEIFITSKLWDADHDKAAA--AIEDSLKKLNVDYM 118
Query: 468 DLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 647
D+YL+H P M L + W+ + +A G K+IG+SNF+ E++ ++ +
Sbjct: 119 DMYLMHSPGTMGAEKRL-------EAWKALEEAVDAGKIKTIGVSNFDVEELDHLLANCR 171
Query: 648 EKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVG 827
KP+ QIE + EL + C I + AY+P AQ A +D +
Sbjct: 172 IKPAVNQIESHPFFAHEELREACISRGIHIQAYSPM-------AQGQA----LDRPEIKT 220
Query: 828 IAQKYNKTVPQVALRF 875
IA K+ KT Q+ L++
Sbjct: 221 IASKHGKTPAQILLKW 236
>UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like
protein 1; n=14; Eutheria|Rep: Aldo-keto reductase
family 1 member C-like protein 1 - Homo sapiens (Human)
Length = 302
Score = 121 bits (292), Expect = 2e-26
Identities = 86/261 (32%), Positives = 138/261 (52%), Gaps = 15/261 (5%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 314
+++L+ G +PV+ GT+ H PK + + T A++ G+ HID+AY Y E+
Sbjct: 10 SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEE 62
Query: 315 QVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 491
+VG+A+ +K ++G +KRE IF T KLW ++ E V PAL +SL+ L +YVDL++IH P
Sbjct: 63 EVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVP 122
Query: 492 IAMFE-----------NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 638
AM + + +L+ V+ DTW + K GL
Sbjct: 123 FAMKQPGKELLPKDASGEIILETVELCDTWELELILNKPGLR------------------ 164
Query: 639 SGLEKPSALQ-IELNLNLQQPELFKFCRENDIVVMAYTPFGS-LFPSKAQPXAPPPRIDD 812
KP+ Q +E + L Q +L +FC+ DIV++AY+ GS P P P +++
Sbjct: 165 ---YKPTCNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALGSQRDPQWVDPDC-PHLLEE 220
Query: 813 ERLVGIAQKYNKTVPQVALRF 875
L IA+K++++ QVALR+
Sbjct: 221 PILKSIAKKHSRSPGQVALRY 241
>UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep:
Aldo-keto reductase - Helicobacter hepaticus
Length = 292
Score = 120 bits (290), Expect = 4e-26
Identities = 81/246 (32%), Positives = 131/246 (53%), Gaps = 3/246 (1%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 326
L++G IP + LGTW R VV E AV A + GY HIDTA YG E VG
Sbjct: 17 LNNGNKIPKLGLGTW---RIDDNVV------EAAVREAFKVGYRHIDTAQAYGNERGVGE 67
Query: 327 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI---A 497
A+ K +KRE +FIT+K+ Y + + ++ SL+ + L+++DL LIH P +
Sbjct: 68 AVRKS---KIKREELFITSKIRAEYKDYKSASASIDTSLKTMKLDFIDLMLIHSPQPWNS 124
Query: 498 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 677
+ D +NV+ + + DA+K G +SIG+SNF Q+ ++ I+ + KP+A QI
Sbjct: 125 FRKGDYFKENVE---VYNALEDAQKAGKVRSIGVSNFLQKDLENILKNCKTKPAANQILC 181
Query: 678 NLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVP 857
++ L +C++ +I+ AY+P A + D R++ +A+KYN +
Sbjct: 182 HIGNTPFTLLDYCKKQNILAEAYSPI-----------AHGELLKDPRVIELAKKYNVSPA 230
Query: 858 QVALRF 875
Q+ +R+
Sbjct: 231 QICIRY 236
>UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=10;
Pezizomycotina|Rep: Related to aldo-keto reductase YPR1
- Neurospora crassa
Length = 322
Score = 120 bits (290), Expect = 4e-26
Identities = 87/257 (33%), Positives = 130/257 (50%), Gaps = 8/257 (3%)
Frame = +3
Query: 129 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQ-VTNDTEQAVIYALEAGYTHIDTAYKYG 305
++P+L+LS G IP++ G + G ++ A + AL AGY H+D A YG
Sbjct: 23 LIPSLKLSDGNEIPMLGYGLGTANYKSGDSADTISEPIVNATLTALNAGYAHLDGAEVYG 82
Query: 306 IEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 485
E ++GRA+ + L R S++ITTK + V + +SLE L L+YVDLYL+H
Sbjct: 83 NEVELGRAIAQ---SKLPRSSLYITTK--TIVRAGDTVTQSFNRSLEKLGLDYVDLYLLH 137
Query: 486 WPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID--SGLEKPS 659
P +N L WR M K G+ KSIG+SNF +Q + D GL+ P
Sbjct: 138 SPF-FAKNPEQLQ-----AAWREMEKIKDSGMAKSIGVSNFLISHLQTLFDIPGGLQYPP 191
Query: 660 AL-QIELNLNLQQ----PELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLV 824
+ QIE + LQ +L FCRE I + AY+P ++ +KA+P P
Sbjct: 192 VVNQIEYHPYLQHVVEGEDLVAFCREKHIAIAAYSPLTAI--TKARPGPVDPIYTQ---- 245
Query: 825 GIAQKYNKTVPQVALRF 875
+A+KY + ++A R+
Sbjct: 246 -LAKKYGVSEAEIAFRW 261
>UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7;
Saccharomycetales|Rep: Aldo/keto reductase - Pichia
stipitis (Yeast)
Length = 323
Score = 120 bits (290), Expect = 4e-26
Identities = 80/239 (33%), Positives = 121/239 (50%), Gaps = 10/239 (4%)
Frame = +3
Query: 189 WLGH-RPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRE 365
WL RP+ + +T + +++ ALE GY HIDTA Y +V A+ K G+ RE
Sbjct: 35 WLKKGRPEEEQNTLTTELVDSILLALENGYNHIDTAEVYTTHPEVAAAVKKS---GIARE 91
Query: 366 SIFITTKLWNSYHEREQVIPA----LRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVD 533
+FITTK + + + ++L+ L +YVDL+LIH P F + +
Sbjct: 92 DLFITTKYTPGFRTFPAISSGPTEFIDRALKELETDYVDLFLIHSP---FFEEKVSRGQT 148
Query: 534 FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQR---IIDSGLEKPSALQIELN--LNLQQP 698
W +IDAKK G + IG+SNF++E ++R + + P QIE + L Q P
Sbjct: 149 LESAWAEVIDAKKAGKVRHIGVSNFSKEHLERTFKVAGNPDFYPKVNQIEFHPYLQNQSP 208
Query: 699 ELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQVALRF 875
+ KF +ENDI++ AY P +LF K E + +A+KY KT Q+ LR+
Sbjct: 209 GIIKFAQENDILIEAYGPLSTLFRIKQNGVDVEDHPLKELIPKLAEKYGKTDAQILLRY 267
>UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Oceanobacillus iheyensis
Length = 280
Score = 119 bits (287), Expect = 9e-26
Identities = 81/248 (32%), Positives = 128/248 (51%)
Frame = +3
Query: 132 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 311
+P + L G IP V GT+ R G ND QA+ A++ GY IDTAY Y E
Sbjct: 5 IPNVTLHDGLTIPKVGFGTY---RLNG------NDGVQAINNAIDHGYRLIDTAYNYENE 55
Query: 312 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 491
VG A+ + + RE + IT+KL YH ++ + +++SL NL+Y DLYLIHWP
Sbjct: 56 GTVGEAVRRSSTP---REQLLITSKLPGRYHHYDKAVTTIQESLYRANLDYYDLYLIHWP 112
Query: 492 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 671
+ + D +++ W+ +I+AK+ G +SIG+ NF E ++R+ E P+ QI
Sbjct: 113 ------NPIQD--IYVEAWQALIEAKRRGYIRSIGVCNFLPEHLERLKQETGELPTINQI 164
Query: 672 ELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKT 851
EL+ Q + K+ +E+ I +++P +D L +A +N+T
Sbjct: 165 ELHPFFNQEDQRKWHQEHQIATESWSPLA----------RTNDVLDHPVLQKLASNHNRT 214
Query: 852 VPQVALRF 875
V Q+ LR+
Sbjct: 215 VSQIILRW 222
>UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase
family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto
reductase family - Enterococcus faecalis (Streptococcus
faecalis)
Length = 279
Score = 119 bits (287), Expect = 9e-26
Identities = 79/250 (31%), Positives = 128/250 (51%), Gaps = 1/250 (0%)
Frame = +3
Query: 129 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 308
+ T+ L++G IP + LG + P + +V E+ +I GY IDTA YG
Sbjct: 5 LADTVTLNNGTKIPGMGLGVF--QIPDEETAKVV---EEGIIN----GYRLIDTAQIYGN 55
Query: 309 EDQVGRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 485
E G + + GL RE +F+T+K+WN++ ++ I A SLE L L+Y+DLYLIH
Sbjct: 56 ESGTGAGIKAGLAATGLNREDLFVTSKVWNAHISYDETIQAFNDSLERLGLDYLDLYLIH 115
Query: 486 WPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL 665
WP N + ++W+ + G K+IG+SNF ++ ++ P
Sbjct: 116 WP----------GNNSYKESWQALETLYAEGKVKAIGVSNFQVHHLEDLLSYAKVVPVIN 165
Query: 666 QIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYN 845
Q+EL+ L Q E+ FC ++DI V A++P + Q + +E ++ IA+ +N
Sbjct: 166 QVELHPKLDQKEVRDFCEKHDIKVQAWSPL-----MQGQ------LLSNETILAIAENHN 214
Query: 846 KTVPQVALRF 875
K+ QV LR+
Sbjct: 215 KSAAQVILRW 224
>UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy
chain; n=3; Saccharomycetaceae|Rep: D-arabinose
dehydrogenase [NAD(P)+] heavy chain - Saccharomyces
cerevisiae (Baker's yeast)
Length = 344
Score = 119 bits (286), Expect = 1e-25
Identities = 86/230 (37%), Positives = 130/230 (56%), Gaps = 25/230 (10%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 326
L++G IP + LGT P K+ + T+QAV A++AGY HIDTA+ Y E VG
Sbjct: 27 LNNGVRIPALGLGT---ANPHEKLAE----TKQAVKAAIKAGYRHIDTAWAYETEPFVGE 79
Query: 327 ALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 503
A+ + +G +KRE +FITTK+W ++V +L +SL+ L LEYVDL L HWP+ F
Sbjct: 80 AIKELLEDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLLQHWPLC-F 136
Query: 504 EN-----------DTLLDNV---------DFLDTWRGM----IDAKKLGLTKSIGISNFN 611
E T +D+ D+L+T++ + +D ++IG+SNF+
Sbjct: 137 EKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPND-HRVRAIGVSNFS 195
Query: 612 QEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 761
E ++R+I KP+ Q+E + +L Q EL KFC +DI++ AY+P GS
Sbjct: 196 IEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGS 245
>UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=2; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus gasseri (strain ATCC 33323 / DSM 20243)
Length = 273
Score = 118 bits (285), Expect = 1e-25
Identities = 80/215 (37%), Positives = 115/215 (53%)
Frame = +3
Query: 231 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHER 410
+ T+QAV+ A E GY IDTA Y E QVG A+ + GL R+ +FITTK +E
Sbjct: 25 DQTKQAVLSAFEEGYRLIDTAQYYQNEQQVGEAVK---ASGLNRDEVFITTKTMTDGYED 81
Query: 411 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 590
++ L +SL + L+Y DL LIHWP+ +D +DTW + A K G T++
Sbjct: 82 TKI--GLDESLRRIGLDYFDLVLIHWPMG---HD--------IDTWHALEAAYKAGKTRA 128
Query: 591 IGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFP 770
IGISNFN Q +I +P QIE +L LQQ ++ +F + +IV +Y+P G+
Sbjct: 129 IGISNFNSRQTLDLIHQSSVRPMVDQIETHLFLQQWKMHEFLEKENIVHESYSPLGN--- 185
Query: 771 SKAQPXAPPPRIDDERLVGIAQKYNKTVPQVALRF 875
I + L I++KY K+ QV LR+
Sbjct: 186 ------GQQNLISNPVLKEISEKYGKSPIQVILRY 214
>UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Lactococcus lactis|Rep: Oxidoreductase,
aldo/keto reductase family - Lactococcus lactis subsp.
cremoris (strain MG1363)
Length = 281
Score = 118 bits (285), Expect = 1e-25
Identities = 88/243 (36%), Positives = 124/243 (51%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 326
L+ G IP LG + P+G+ TE AV AL GY HIDTA+ Y E VGR
Sbjct: 7 LNDGNIIPQFGLGVY--QIPEGEA------TENAVKEALRLGYRHIDTAHAYQNERSVGR 58
Query: 327 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 506
A+ S G+ I+IT+KLW S + + A+ + LE LNL+ +DL L+H + +
Sbjct: 59 AI---HSSGIPISEIWITSKLWPS--DYDDASQAIERMLELLNLKQIDLLLLHQQVGNYR 113
Query: 507 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLN 686
W + +A K G KSIGISNF+ E++ + + KPSALQ+E +
Sbjct: 114 K-----------AWIALENAVKSGKVKSIGISNFDGERLVDLFNFADIKPSALQVETHPY 162
Query: 687 LQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQVA 866
QQ EL +F + + ++ P G +D+ RL IAQKYNKTV Q+
Sbjct: 163 HQQKELQEFLKPYGTKIESWYPLG---------HGDQRLLDESRLKKIAQKYNKTVAQII 213
Query: 867 LRF 875
LR+
Sbjct: 214 LRW 216
>UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3;
Saccharomycetales|Rep: Conjugated polyketone reductase
C1 - Candida parapsilosis (Yeast)
Length = 304
Score = 118 bits (285), Expect = 1e-25
Identities = 85/258 (32%), Positives = 135/258 (52%), Gaps = 14/258 (5%)
Frame = +3
Query: 144 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVI----YALEAGYTHIDTAYKYGIE 311
+LS+G IP VA GT + +G ND ++ +I AL +G+ HID A YG
Sbjct: 9 KLSNGNKIPAVAFGTGTKYFKRGH-----NDLDKQLIGTLELALRSGFRHIDGAEIYGTN 63
Query: 312 DQVGRALTKKFSEGLKRESIFITTKL------WNSYHEREQ-VIPALRKSLENLNLEYVD 470
++G AL + GL R+ +FIT K ++ H + Q AL+ LE+L LEYVD
Sbjct: 64 KEIGIALK---NVGLNRKDVFITDKYNSGNHTYDGKHSKHQNPYNALKADLEDLGLEYVD 120
Query: 471 LYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 650
LYLIH+P ++ D ++ WR + AK GL ++IG+SNF E ++ I+D+ +
Sbjct: 121 LYLIHFPYISEKSH----GFDLVEAWRYLERAKNEGLARNIGVSNFTIENLKSILDANTD 176
Query: 651 K-PSALQIELNLNLQQ--PELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERL 821
P QIE + LQ P + ++ ++ I++ AY P G + + P D+ L
Sbjct: 177 SIPVVNQIEFSAYLQDQTPGIVEYSQQQGILIEAYGPLGPITQGRPGPL-------DKVL 229
Query: 822 VGIAQKYNKTVPQVALRF 875
+++KY + Q+ LR+
Sbjct: 230 SKLSEKYKRNEGQILLRW 247
>UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide
reductase; n=4; Saccharomycetales|Rep: NADPH-dependent
alpha-keto amide reductase - Saccharomyces cerevisiae
(Baker's yeast)
Length = 312
Score = 118 bits (285), Expect = 1e-25
Identities = 82/248 (33%), Positives = 130/248 (52%), Gaps = 5/248 (2%)
Frame = +3
Query: 147 LSSGGNIPVVAL-GTWLG-HRPKGKVVQVTNDTEQAVIYALEA-GYTHIDTAYKYGIEDQ 317
L++G IP +A+ GT ++ + +N + ++YAL+ G HID A Y +
Sbjct: 10 LNNGNKIPAIAIIGTGTRWYKNEETDATFSNSLVEQIVYALKLPGIIHIDAAEIYRTYPE 69
Query: 318 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
VG+AL+ +E R +IF+T K + L +L+ + +YVDLYL+H P
Sbjct: 70 VGKALS--LTEK-PRNAIFLTDKYSPQIKMSDSPADGLDLALKKMGTDYVDLYLLHSPFV 126
Query: 498 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 677
E ++ + + W+ M K G K+IG+SNF E +QRI+ KP QIE
Sbjct: 127 SKE----VNGLSLEEAWKDMEQLYKSGKAKNIGVSNFAVEDLQRILKVAEVKPQVNQIEF 182
Query: 678 N--LNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKT 851
+ L Q P ++KFC+E+DI+V AY+P G L AQ + P E + +++KY K+
Sbjct: 183 SPFLQNQTPGIYKFCQEHDILVEAYSPLGPLQKKTAQDDSQP---FFEYVKELSEKYIKS 239
Query: 852 VPQVALRF 875
Q+ LR+
Sbjct: 240 EAQIILRW 247
>UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase
family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 286
Score = 118 bits (284), Expect = 2e-25
Identities = 87/249 (34%), Positives = 126/249 (50%), Gaps = 1/249 (0%)
Frame = +3
Query: 132 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 311
VP + L++G +P++ G + P K TE+ V A++ GY IDTA Y E
Sbjct: 3 VPKVTLNNGVEMPILGYGVF--QIPPEK-------TEECVYEAIKVGYRLIDTAASYMNE 53
Query: 312 DQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 488
+ VGRA+ + EG+ +RE +F+TTKLW S E A KSL+ L LEY+DLYLIH
Sbjct: 54 EGVGRAIKRAIDEGIVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLIHQ 113
Query: 489 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 668
P D W+ M + K GL ++IG+SNF +++ ++ P+ Q
Sbjct: 114 PFG-----------DVHCAWKAMEEMYKDGLVRAIGVSNFYPDRLMDLMVHHEIVPAVNQ 162
Query: 669 IELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNK 848
IE++ Q+ E +F R +I A+ PF + Q L IA+KY K
Sbjct: 163 IEIHPFYQRQEEIEFMRNYNIQPEAWGPFAEGRKNIFQNGV---------LRSIAEKYGK 213
Query: 849 TVPQVALRF 875
TV QV LR+
Sbjct: 214 TVAQVILRW 222
>UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1;
Filobasidiella neoformans|Rep: Aldo-keto reductase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 303
Score = 118 bits (283), Expect = 3e-25
Identities = 76/215 (35%), Positives = 115/215 (53%), Gaps = 1/215 (0%)
Frame = +3
Query: 234 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF-SEGLKRESIFITTKLWNSYHER 410
+T V +ALEAGY H+DTA Y E G+A+ + G RE IF+T+KL N+
Sbjct: 55 ETYDCVKWALEAGYRHVDTAEWYENEAPCGKAIADFLKATGTSREEIFLTSKLKNN-SSY 113
Query: 411 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 590
EQ L+ SL+ +EY DLYL+H I + NV W+ + DA+ GL KS
Sbjct: 114 EQAFVDLKGSLKRSGVEYFDLYLMHSAIG---GPVIRKNV-----WKALCDAQSQGLVKS 165
Query: 591 IGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFP 770
IG+SNF ++ IQ ID + P+ Q++L+ ++ PE+ + C +N+I++ A+ P
Sbjct: 166 IGVSNFGKKHIQEFIDQKVPLPTVNQVDLHPFMRHPEIVEICEQNEILLEAWGPL----- 220
Query: 771 SKAQPXAPPPRIDDERLVGIAQKYNKTVPQVALRF 875
A R D +V IA++ K Q+ LR+
Sbjct: 221 ------ARAMRFDHPVVVKIAKEKGKDAAQIMLRW 249
>UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus
niger|Rep: Putative frameshift - Aspergillus niger
Length = 357
Score = 118 bits (283), Expect = 3e-25
Identities = 87/261 (33%), Positives = 135/261 (51%), Gaps = 17/261 (6%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
T L++G IP + +GT+ Q + E+ V L+ G IDTA YG+E Q
Sbjct: 37 TYTLNTGAKIPALGVGTF----------QDPDSQEETVCQVLQRGMRLIDTARVYGVEQQ 86
Query: 318 VGRALTKKFSEGLKRESIFITTKLW-NSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VGR + K G+ RE IF+ TKLW N +H + V A+ SL +L YVDL L+H+P
Sbjct: 87 VGRGIKKS---GVPREEIFLGTKLWCNDFHP-DDVERAVDDSLRDLYTPYVDLLLMHYPC 142
Query: 495 AM------FENDT----LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSG 644
F D + F+DTWR + K G ++IG+SNF++ +I+ ++
Sbjct: 143 TFKRGEDRFPRDAEGRMIHGETTFVDTWRALEKVVKTGKVRAIGVSNFSKGEIETLLRET 202
Query: 645 LEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSL--FPSKA---QPXAPPPRID 809
P+ Q+E++ LQQ ++ RE I V+ ++P G++ F +A + A R+
Sbjct: 203 STVPAVHQMEVHPYLQQKGFNEWLREKGIHVVQFSPLGNMNDFYRQAGWSKEIAHMMRVI 262
Query: 810 DERLV-GIAQKYNKTVPQVAL 869
D+ ++ I QKY K+ QV L
Sbjct: 263 DQPILKEIGQKYGKSPVQVVL 283
>UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Rep:
ABL209Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 310
Score = 117 bits (281), Expect = 5e-25
Identities = 87/250 (34%), Positives = 130/250 (52%), Gaps = 6/250 (2%)
Frame = +3
Query: 144 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY-ALEAGYTHIDTAYKYGIEDQV 320
+LS G IP V LG V QV+ T Q ++Y ALE GY D+A Y ED V
Sbjct: 14 RLSDGTQIPSVGLG----------VYQVSEQTVQDLVYEALEVGYRLFDSAQAYHNEDGV 63
Query: 321 GRALTK--KFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLN-LEYVDLYLIHWP 491
R + K + G +RE ++ TTK+ H E +L KSL L Y+DL L+H P
Sbjct: 64 ARGIAAWLKHAPGRRREDVYFTTKINTQNHGYEATKKSLEKSLHAAGPLGYIDLVLVHAP 123
Query: 492 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID-SGLE-KPSAL 665
++ D L TW+ + +A G +SIG+SN+ Q+ + ++ GL+ +P
Sbjct: 124 MS--------DRTRRLGTWQALEEAVVEGQVRSIGVSNYGQQHLSELLGWEGLKIRPVVN 175
Query: 666 QIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYN 845
Q+E+N L + EL ++CREN+I V A++P L K R+DD L +A +Y+
Sbjct: 176 QVEINPWLCRQELVQYCRENNIAVQAFSP---LMRGK--------RLDDPILQKVAHQYD 224
Query: 846 KTVPQVALRF 875
K V Q+ +R+
Sbjct: 225 KGVAQILVRW 234
>UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1;
Klebsiella pneumoniae|Rep: Putative uncharacterized
protein - Klebsiella pneumoniae
Length = 279
Score = 116 bits (280), Expect = 6e-25
Identities = 64/176 (36%), Positives = 106/176 (60%)
Frame = +3
Query: 234 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHERE 413
D + + AL+AG+ H DTA Y ED VGRAL +++E + RE +FIT+K+
Sbjct: 28 DVDSLIRQALKAGFRHFDTAQAYFNEDGVGRAL--RYTE-VPREQLFITSKIRGRDMGYA 84
Query: 414 QVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSI 593
+ + + ++LE L +EY++L+LIHWPI N+ +++TW I+ + GL +SI
Sbjct: 85 RTLVSFNETLERLGVEYLELFLIHWPIPA-------KNL-YVETWEASIELEASGLIRSI 136
Query: 594 GISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 761
G+SNF + I+R+I+ P+ Q+EL+ + QQ ++ + E I + +Y+PFGS
Sbjct: 137 GVSNFTCQHIERLIEDTGVVPAVNQLELHPHFQQCDVRDYHHEAGIAIQSYSPFGS 192
>UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 339
Score = 116 bits (280), Expect = 6e-25
Identities = 82/263 (31%), Positives = 131/263 (49%), Gaps = 17/263 (6%)
Frame = +3
Query: 132 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 311
+P+ L++G +P V +G W G G+ N+ A++ A++ GY H+DTA Y E
Sbjct: 5 IPSFTLNTGAKLPSVGMGCWQGQPGPGR----DNELVDALVRAIKVGYRHLDTATGYRNE 60
Query: 312 DQVGRALTKKFSEGLKRESIFITTKLW-NSYHEREQVIPALRKSLENLNLEYVDLYLIHW 488
+VG+A+ + G+ R IF+TTKL H+ V+ L SL L ++Y+DL+L+HW
Sbjct: 61 AEVGQAVRQS---GVARSEIFVTTKLRPGGVHD---VVQELENSLNELGIDYIDLWLLHW 114
Query: 489 PIAMFENDTLLDNVD-------------FLDTWRGMIDA---KKLGLTKSIGISNFNQEQ 620
P ++D + F +TW M D G K+IG+SNF+ +
Sbjct: 115 PQGFTKDDGGFGTGESFGLEHQKHLGPTFNETWAKMEDVFLNSHKGKVKAIGVSNFSIKN 174
Query: 621 IQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPP 800
++ + + P+ QIE + L + EL K+C+ I V AY+P G S
Sbjct: 175 LEILAKTSKVTPAVNQIEAHPYLPEHELVKYCKHKSIHVTAYSPLGQYNASIH------- 227
Query: 801 RIDDERLVGIAQKYNKTVPQVAL 869
+D+ L IA+K++ T VAL
Sbjct: 228 --EDKDLNEIAKKHDVTAATVAL 248
>UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=6;
Pezizomycotina|Rep: Aldo/keto reductase family proteins
- Aspergillus oryzae
Length = 294
Score = 116 bits (280), Expect = 6e-25
Identities = 79/247 (31%), Positives = 126/247 (51%)
Frame = +3
Query: 135 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 314
P ++L+ +IP++ GT + V + +A+ A+ GY H+D A YG E
Sbjct: 10 PRVKLNDNVSIPILGYGTGTAWYKQAGDDSVNRELVEAIKTAIRLGYRHLDGAEVYGTEA 69
Query: 315 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
++G A+ + G+ RE +F+TTK+ + + + A+ +SL L L YVDLYLIH P
Sbjct: 70 ELGVAIKES---GIPREELFVTTKVITNIAD---IPSAIDQSLRKLQLNYVDLYLIHSPF 123
Query: 495 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 674
++D L W M ++ G K+IG+SN++Q ++ + + + P QIE
Sbjct: 124 -FAKSDGELQQA-----WAAMEKVQQAGKAKAIGVSNYHQSHLEATLKTAVIAPVINQIE 177
Query: 675 LNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTV 854
+ LQQ EL +F RE DI + +Y G L P P P D ++ +A KY T
Sbjct: 178 HHPYLQQEELLRFQREKDIKIASY---GPLTPILRAPGGPV----DPKVSELAAKYKVTE 230
Query: 855 PQVALRF 875
+V LR+
Sbjct: 231 GEVLLRW 237
>UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8;
Saccharomycetales|Rep: Probable oxidoreductase YJR096W -
Saccharomyces cerevisiae (Baker's yeast)
Length = 282
Score = 116 bits (280), Expect = 6e-25
Identities = 76/209 (36%), Positives = 116/209 (55%), Gaps = 6/209 (2%)
Frame = +3
Query: 144 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 323
+LS+G IP +ALGT+ P+ + ++ V ++ GY H DTA YG E +VG
Sbjct: 7 KLSNGFKIPSIALGTY--DIPRSQTAEI-------VYEGVKCGYRHFDTAVLYGNEKEVG 57
Query: 324 RALTKKFSE---GLKRESIFITTKLWNSYHEREQVIPALRKSLENLN-LEYVDLYLIHWP 491
+ K +E KRE IF TTKLWNS + ++ A+R+ L ++ L+Y+DL LIH P
Sbjct: 58 DGIIKWLNEDPGNHKREEIFYTTKLWNSQNGYKRAKAAIRQCLNEVSGLQYIDLLLIHSP 117
Query: 492 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID--SGLEKPSAL 665
+ E L L+TWR M +A GL KSIG+SN+ ++ I +++ KP
Sbjct: 118 L---EGSKLR-----LETWRAMQEAVDEGLVKSIGVSNYGKKHIDELLNWPELKHKPVVN 169
Query: 666 QIELNLNLQQPELFKFCRENDIVVMAYTP 752
QIE++ + + EL +C+ +VV A+ P
Sbjct: 170 QIEISPWIMRQELADYCKSKGLVVEAFAP 198
>UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_291_56367_57278 - Giardia lamblia
ATCC 50803
Length = 303
Score = 116 bits (279), Expect = 8e-25
Identities = 72/224 (32%), Positives = 112/224 (50%), Gaps = 15/224 (6%)
Frame = +3
Query: 243 QAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSE---GLKRESIFITTKLWNSYHERE 413
+A+ A++ GY H D AY+YG E +G + F++ G+KRE ++I +KLW ++HE E
Sbjct: 19 EAIRSAVKLGYRHFDCAYRYGNERMIGEVFKEIFNDDSYGVKREDLWIVSKLWPNFHEPE 78
Query: 414 QVIPALRKSLENLNLEYVDLYLIHWPIA---MFEND---------TLLDNVDFLDTWRGM 557
+V + ++L +L LEY+D++L+HWP+A + + D TLL TW M
Sbjct: 79 KVAYQISETLRDLQLEYLDVFLMHWPLAIKHLADRDYASSDGKGGTLLGTTPIRKTWEAM 138
Query: 558 IDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVV 737
T+ IG+SN + ++ KP Q E L +FC N I V
Sbjct: 139 EACVDKKQTRFIGVSNMGTAMLVDLLSYCRIKPFTNQFESQPYFPNDRLIEFCNSNGIYV 198
Query: 738 MAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQVAL 869
AY P G + + A P + D L +A+K N TV ++ L
Sbjct: 199 TAYRPLG----GRCRVDAKAP-LTDPALEELAKKANLTVSELIL 237
>UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1;
Corynebacterium jeikeium K411|Rep: Putative
oxidoreductase - Corynebacterium jeikeium (strain K411)
Length = 285
Score = 116 bits (278), Expect = 1e-24
Identities = 74/211 (35%), Positives = 113/211 (53%), Gaps = 2/211 (0%)
Frame = +3
Query: 132 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTN-DTEQAVIYALEAGYTHIDTAYKYGI 308
VPTL+++ G P + LG W Q+++ DT +V A+E GY HIDTA YG
Sbjct: 8 VPTLEMNDGKTTPQLGLGVW----------QLSDEDTYTSVRAAIETGYRHIDTAAIYGN 57
Query: 309 EDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 485
E+ VGRA+ G ++RE +FITTKLWN+ ++ A +S + L ++YVDLYL+H
Sbjct: 58 EEAVGRAVADAVKAGDVQREELFITTKLWNA--DQACGKEAFAESQKKLGMDYVDLYLLH 115
Query: 486 WPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL 665
WP ++ F+ + M + ++ G SIG+ NF E + + +G P+
Sbjct: 116 WPCPQADS--------FVQAYDSMAEIQQSGGATSIGVCNFYPEALDALKQAG-HTPAVN 166
Query: 666 QIELNLNLQQPELFKFCRENDIVVMAYTPFG 758
QIE++ Q E R+ IV A++P G
Sbjct: 167 QIEIHPGFSQAEQRSDNRDRGIVTEAWSPLG 197
>UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4;
Actinomycetales|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 287
Score = 115 bits (277), Expect = 1e-24
Identities = 76/248 (30%), Positives = 128/248 (51%)
Frame = +3
Query: 132 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 311
+P L+L G IP + LGTW + ++ E AV +AL++GY +DTA++Y E
Sbjct: 13 IPRLKLPHGHTIPRLGLGTW---------PMLEDECETAVRFALQSGYRLVDTAFQYRNE 63
Query: 312 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 491
+ VGR + + G+ R +FI++K H + V A +SL L L+++D+++ HWP
Sbjct: 64 EAVGRGIR---TAGVPRSELFISSKFNKESHSIDGVQRAYDESLRKLGLDHLDMFMCHWP 120
Query: 492 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 671
+ ++D W+G++ + G K+IG+SNF ++ IID+ P QI
Sbjct: 121 VPALGK--------YVDAWKGLVKLLEEGRVKAIGVSNFKPAHLKDIIDATGVVPDVNQI 172
Query: 672 ELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKT 851
+L+ +L + E R IV A++P G +A P ++ IAQ+ +K+
Sbjct: 173 QLSPDLARTEPRAVHRLLGIVTEAWSPIGRSSGLRANPL----------IIEIAQRLDKS 222
Query: 852 VPQVALRF 875
QV LR+
Sbjct: 223 PAQVLLRW 230
>UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Pseudoalteromonas atlantica (strain T6c / BAA-1087)
Length = 273
Score = 114 bits (275), Expect = 2e-24
Identities = 65/177 (36%), Positives = 98/177 (55%), Gaps = 1/177 (0%)
Frame = +3
Query: 231 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHER 410
+D + AV AL+ GY HIDTA Y E +VG A++ + + R +F+TTK+W
Sbjct: 24 DDAKLAVENALDVGYRHIDTAQAYENEAEVGDAIS---ASKISRGELFVTTKVWFDNLSA 80
Query: 411 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 590
++ I +++ SL LN +YVDL L+HWP D + ++L + K+ GLT+
Sbjct: 81 DKFITSVQNSLTQLNTDYVDLLLVHWP----SPDNKVSMAEYLKELKA---CKERGLTRH 133
Query: 591 IGISNFNQEQIQRIID-SGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 758
IG+SNF Q Q+ + G + QIE++ N Q EL +C+ N+I V AY P G
Sbjct: 134 IGVSNFTQSQLDEALSILGKDHILTNQIEVHPNFQNKELVAYCQRNNIQVTAYMPLG 190
>UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=3; Lactobacillales|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 292
Score = 114 bits (275), Expect = 2e-24
Identities = 78/244 (31%), Positives = 123/244 (50%), Gaps = 1/244 (0%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 326
L+SG +P++ G + VQ +QAV+ A++ GY IDTA YG E +VG
Sbjct: 6 LASGIEMPLLGFGVFQ--------VQEKGAAKQAVLDAIKTGYRLIDTAASYGNEREVGE 57
Query: 327 ALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 503
A+ + ++G+ KRE +F+T+K+W +Q A++ SL+ LNL+Y+DLYLIH P
Sbjct: 58 AILEAINQGIVKREELFVTSKMWVQDVSAQQATAAIQSSLQRLNLDYLDLYLIHQPYN-- 115
Query: 504 ENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNL 683
D WR M A + G K+IG+SNF+ Q+ + + KP QIE+N
Sbjct: 116 ---------DVFGAWRAMESAYRSGQLKAIGVSNFDIAQLTNLAEFSDIKPMLNQIEVNP 166
Query: 684 NLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQV 863
Q + + + + V A+ PF + L IA K++K++ Q+
Sbjct: 167 FQQNKKDITYFSQYGVQVEAWAPFAE---------GKNDLFSNILLRKIADKHHKSIAQI 217
Query: 864 ALRF 875
LR+
Sbjct: 218 VLRW 221
>UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome B of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 302
Score = 114 bits (275), Expect = 2e-24
Identities = 74/215 (34%), Positives = 115/215 (53%), Gaps = 3/215 (1%)
Frame = +3
Query: 126 LIVPTLQLSSGGNIPVVALGTWLG-HRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKY 302
+ VP ++LS+G IP + G+ RP G+ + + AV+ A+ AG+ HIDTA Y
Sbjct: 1 MTVPKVKLSNGLEIPAIGFGSGTKWKRPPGEKEE--RELIDAVVSAINAGHLHIDTAEFY 58
Query: 303 GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 482
G E Q+G A+ + G+ R+ IF+T+K + I ++ L+ L +Y DL+LI
Sbjct: 59 GTEKQIGEAIKES---GVPRKDIFLTSKTLFGLLA-DDPIESISNQLKTLQTDYFDLFLI 114
Query: 483 HWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 662
H P ND + N D W + + GL K+IG+SN + +++ II KP
Sbjct: 115 HVP----PNDDI--NYDLAKAWGVLEQLYEKGLAKAIGVSNHSPAELETIIKVAKIKPHV 168
Query: 663 LQIELNLNLQQPE--LFKFCRENDIVVMAYTPFGS 761
QIE + LQ+P + FC+++DIVV Y+P S
Sbjct: 169 NQIEFHPLLQEPTPGIVDFCKQHDIVVEGYSPLAS 203
>UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=5; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus brevis (strain ATCC 367 / JCM 1170)
Length = 282
Score = 114 bits (274), Expect = 3e-24
Identities = 83/249 (33%), Positives = 124/249 (49%)
Frame = +3
Query: 129 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 308
I T +L+ G +PV+ GT+L + Q T +T A+ A +AGY DTA Y
Sbjct: 6 ITATRKLADGRQMPVMGFGTYLLND------QPTMNT--AIQTAWDAGYRMFDTAMLYRN 57
Query: 309 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 488
ED +G A+ + GL RE +F+T+K+ +Q + A+ SL+ L +Y+DL LIHW
Sbjct: 58 EDILGPAIQQL---GLPREGLFLTSKVAEIVQGYDQTMKAVEGSLKRLQTDYLDLLLIHW 114
Query: 489 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 668
P+ F DTWR + K G KSIG+SN+ ++ + E P Q
Sbjct: 115 PV----------REHFFDTWRALEQLKADGQVKSIGVSNYTIAHLELLATKAKEMPVVNQ 164
Query: 669 IELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNK 848
+E + L Q L + +E+DIV A++P G +DD L +A +NK
Sbjct: 165 VEYHPYLNQQALADYDQEHDIVTEAWSPLGRRVV-----------LDDPMLAKMAAHHNK 213
Query: 849 TVPQVALRF 875
+V QV LR+
Sbjct: 214 SVAQVILRW 222
>UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG6084-PA, isoform A - Tribolium castaneum
Length = 493
Score = 113 bits (273), Expect = 4e-24
Identities = 66/159 (41%), Positives = 94/159 (59%), Gaps = 12/159 (7%)
Frame = +3
Query: 435 KSLENLNLEYVDLYLIHWPIAMFENDTL--LD---------NVDFLDTWRGMIDAKKLGL 581
+SL+NL L+Y+D+YL+HWP A+ E +L +D +VDF+DTW+ M + L
Sbjct: 271 ESLKNLQLDYLDVYLMHWPHALKEGPSLHPIDPKTGLFIPSDVDFVDTWKAMEKMHEKDL 330
Query: 582 TKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 761
TKSIGISNFN QI R++ S P QIE + L Q +L KFC + I V +Y+P GS
Sbjct: 331 TKSIGISNFNSNQIDRLLKSAKIAPVINQIECHPYLNQSKLRKFCSDRGITVTSYSPLGS 390
Query: 762 LFPSKA-QPXAPPPRIDDERLVGIAQKYNKTVPQVALRF 875
P++ Q P I+D ++ I KY K+ Q+ LR+
Sbjct: 391 --PARPWQKPGDPYVINDPKIKEIGNKYGKSPAQILLRY 427
Score = 95.9 bits (228), Expect = 1e-18
Identities = 61/190 (32%), Positives = 107/190 (56%), Gaps = 1/190 (0%)
Frame = +3
Query: 309 EDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 485
E + G AL + G ++R+ +F+ +K + + V AL +L+ L + Y+DLYLI
Sbjct: 55 EKRFGVALQQLIEGGKIRRKDLFLMSKFCCT-NTTNLVKAALLDTLKKLQVAYLDLYLIE 113
Query: 486 WPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL 665
P A +++ ++TW M LT++IG+SNFN +QI+RI+++ +P
Sbjct: 114 RPPACKDHN-------LIETWEAMEGLYSEKLTRAIGLSNFNSKQIERILENCTIRPQVN 166
Query: 666 QIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYN 845
QI+ + L Q +L K+C N I V++Y+P G+ + QP + + D R+ IA++YN
Sbjct: 167 QIQCHPYLNQAKLRKYCSNNGIAVISYSPLGA--RNNIQPESLDV-LSDCRIKEIARRYN 223
Query: 846 KTVPQVALRF 875
KT ++ L++
Sbjct: 224 KTPTEIVLKY 233
>UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=1; Rhodobacterales bacterium HTCC2150|Rep:
2,5-diketo-D-gluconic acid reductase A - Rhodobacterales
bacterium HTCC2150
Length = 334
Score = 113 bits (273), Expect = 4e-24
Identities = 82/260 (31%), Positives = 130/260 (50%), Gaps = 14/260 (5%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYA-LEAGYTHIDTAYKYGIED 314
T L++ IP V GT+L ++ND ++ I A ++AGY HIDTA Y E
Sbjct: 39 TFTLNTTTTIPAVGFGTYL----------ISNDDAKSTISAAIQAGYRHIDTASGYQNEK 88
Query: 315 QVGRALTKKF-SEGLKRESIFITTKLW-------NSYHEREQVIPALRKSLENLNLEYVD 470
VG + S G+ R+ +F+T KLW ++ + Q + SL L L+YVD
Sbjct: 89 TVGAGIKAGLQSAGITRKDLFVTAKLWPGNPAWGDAPKTKAQTLDECDASLARLGLDYVD 148
Query: 471 LYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 650
LYLIH P + D L+ WR +++ + G +SIG+SNFN+ + I +GL
Sbjct: 149 LYLIHAP---YGGDMRLEQ------WRALLELQANGKARSIGVSNFNESHLNEIKAAGLP 199
Query: 651 KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVG- 827
P A QIEL+ Q+P+L + ++ I +AY+ L + + + D+ + G
Sbjct: 200 MPDANQIELHPWSQKPDLLAYMDQHAIAPIAYSSLVPLSTWRTKEGQASAKTDEMKAAGT 259
Query: 828 ----IAQKYNKTVPQVALRF 875
+A+KY + Q+ LR+
Sbjct: 260 TFRDMAEKYGVSEAQLLLRW 279
>UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=7;
Magnoliophyta|Rep: Uncharacterized protein At5g01670.2 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 349
Score = 113 bits (273), Expect = 4e-24
Identities = 89/289 (30%), Positives = 145/289 (50%), Gaps = 34/289 (11%)
Frame = +3
Query: 111 FTSADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYAL-EAGYTHID 287
FTS + + +L SG IP V LGTW + + AV+ A+ E GY HID
Sbjct: 6 FTSEGQNMESFRLLSGHKIPAVGLGTW----------RSGSQAAHAVVTAIVEGGYRHID 55
Query: 288 TAYKYGIEDQVGRALTKKFSEGLK----------------RESIFITTKLWN-----SYH 404
TA++YG + +VG+ + + GL+ R+ I +++ L N +
Sbjct: 56 TAWEYGDQREVGQGIKRAMHAGLERRDLFVTSKLWYTLILRKMINLSSPLMNVLVGTCLN 115
Query: 405 ER------EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNV-DFLD-----TW 548
+R E+V PAL+ +L+ L LEY+DLYLIHWPI + E + D LD W
Sbjct: 116 KRCTELSPERVRPALQNTLKELQLEYLDLYLIHWPIRLREGASKPPKAGDVLDFDMEGVW 175
Query: 549 RGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCREND 728
R M + K L ++IG+ NF ++ +++ P+ Q+E++ + + +FC++N+
Sbjct: 176 REMENLSKDSLVRNIGVCNFTVTKLNKLLGFAELIPAVCQMEMHPGWRNDRILEFCKKNE 235
Query: 729 IVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQVALRF 875
I V AY+P GS + I D+ + IA+K NKT Q+ +++
Sbjct: 236 IHVTAYSPLGSQEGGR-------DLIHDQTVDRIAKKLNKTPGQILVKW 277
>UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep:
Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 287
Score = 113 bits (272), Expect = 6e-24
Identities = 76/213 (35%), Positives = 112/213 (52%), Gaps = 2/213 (0%)
Frame = +3
Query: 126 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYG 305
+IVP+++L SG +P++ LGT+ +Q +Q+V AL+AGY DTA YG
Sbjct: 1 MIVPSVRLMSGTQMPLLGLGTYK--------LQDHEQLKQSVSCALQAGYRAFDTAAVYG 52
Query: 306 IEDQVGRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 482
E +G+ L + + GL RE +FI +KL S H LR SLE L+ EY+DLYLI
Sbjct: 53 NEAHLGQVLKELLPKYGLIREDVFIISKLAPSDHGLRAKEGCLR-SLEQLDCEYIDLYLI 111
Query: 483 HWP-IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPS 659
HWP + + + + +W + + G K+IG+SN+ + I+ ++ S P+
Sbjct: 112 HWPGMEGLDPEDSRHSEYRAQSWATLEEFHASGQFKAIGVSNYTAKHIRELLASCRVPPA 171
Query: 660 ALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 758
LQIE L Q EL C E I AY+ G
Sbjct: 172 VLQIECQPKLIQRELRDLCMETGIHFQAYSSLG 204
>UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2;
Corynebacterium|Rep: Putative oxidoreductase -
Corynebacterium diphtheriae
Length = 290
Score = 113 bits (272), Expect = 6e-24
Identities = 77/250 (30%), Positives = 127/250 (50%), Gaps = 1/250 (0%)
Frame = +3
Query: 129 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 308
I+PT+ L+ G +P + GT+ K+ + D +AV A+E GY HIDTA Y
Sbjct: 10 IIPTITLNDGTEMPAIGFGTY-------KLRE--QDAYRAVRSAIEVGYRHIDTASLYKN 60
Query: 309 EDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 485
E++VGRA+ + G + R+ +FITTK+WN H + + ++SL L L+Y+D ++H
Sbjct: 61 EEEVGRAVADAITAGEVARDELFITTKVWNDMHGDQLTQRSFQESLHRLGLDYIDCCMVH 120
Query: 486 WPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL 665
WP + L +++++ + + LG +S+ ++NF E ++ I+ P
Sbjct: 121 WP---WPQKGL-----YVESFAALAKIQGLGQLQSVAVANFYPEVLREIVAETGIAPVLN 172
Query: 666 QIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYN 845
Q+EL+ Q E RE +V A++P G ++ E + IAQ Y
Sbjct: 173 QVELHPGFSQAEQRAVDRELGVVTEAWSPLGR-----------GDSLNAEAITLIAQCYE 221
Query: 846 KTVPQVALRF 875
KT QV LR+
Sbjct: 222 KTPAQVTLRW 231
>UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid
reductase; n=1; Gluconobacter oxydans|Rep: Putative
2,5-diketo-D-gluconic acid reductase - Gluconobacter
oxydans (Gluconobacter suboxydans)
Length = 279
Score = 113 bits (272), Expect = 6e-24
Identities = 76/245 (31%), Positives = 122/245 (49%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
+ G +P + LG W P + +V + A++ GY +DTA Y E+ V
Sbjct: 14 ISFHDGHTMPQIGLGVW--ETPPDETAEVVKE-------AVKLGYRSVDTARLYKNEEGV 64
Query: 321 GRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 500
G+ L IF+TTKLWN + + A +S L +DLYLIHWP+
Sbjct: 65 GKGLED-------HPEIFLTTKLWNDEQGYDSTLRAYEESARLLRRPVLDLYLIHWPMPA 117
Query: 501 FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELN 680
+++TW+ +++ KK G KSIG+SNF E ++RI+D+ P QIEL+
Sbjct: 118 --------QGQYVETWKALVELKKSGRVKSIGVSNFESEHLERIMDATGVVPVVNQIELH 169
Query: 681 LNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQ 860
+ QQ L +F +++I ++ P G K + + DER+ IA+K+++T Q
Sbjct: 170 PDFQQRALREFHEKHNIRTESWRPLG-----KGRV------LSDERIGKIAEKHSRTPAQ 218
Query: 861 VALRF 875
V +R+
Sbjct: 219 VVIRW 223
>UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 310
Score = 113 bits (271), Expect = 7e-24
Identities = 70/212 (33%), Positives = 125/212 (58%), Gaps = 5/212 (2%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
L+L++G ++P+V +GT+ + +G+ V ++ + + G+ IDTA Y E+ +
Sbjct: 26 LRLNNGYDMPLVGIGTY---KVRGREV-----IKRVIDESFAVGFRSIDTAVVYRNEEDI 77
Query: 321 GRALTKKFSE-GLKRESIFITTKLWNSYH-EREQVIPALRKSLENLNLEYVDLYLIHWPI 494
G AL + + LKRE IFIT+KL S + + +++ ++ SL+ L+ Y+DLYLIHWP
Sbjct: 78 GLALKELLPKYNLKREDIFITSKLSPSDNGDPDKIRKSVEDSLKALDTSYLDLYLIHWPG 137
Query: 495 AMFENDTLLDNVDF-LDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID--SGLEKPSAL 665
A + DN + TW +++ ++ GL +SIG+SN+ ++ +++ SG+ KP
Sbjct: 138 ASRILENSPDNPKLRVTTWATLVELQQKGLLRSIGVSNYTVGHLEHLLEHCSGV-KPDVN 196
Query: 666 QIELNLNLQQPELFKFCRENDIVVMAYTPFGS 761
Q+E + + +Q EL +FC + I V AY+ G+
Sbjct: 197 QVECHPHFRQDELIEFCTKQGIHVQAYSSLGT 228
>UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3;
Bacteria|Rep: Putative uncharacterized protein -
Bacteroides capillosus ATCC 29799
Length = 287
Score = 113 bits (271), Expect = 7e-24
Identities = 72/207 (34%), Positives = 108/207 (52%), Gaps = 3/207 (1%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY-ALEAGYTHIDTAYKYGIEDQVG 323
LS+G +IP V GT+ T D + AV+ A+ GY H DTA YG E +G
Sbjct: 10 LSNGLSIPAVGFGTYK-----------TGDGDSAVLSNAIAQGYRHFDTASFYGTETALG 58
Query: 324 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 503
+A+ + + RE F+T+KLW + + + A +LE L +Y+DLYLIHWP
Sbjct: 59 QAVAES---DIPREDFFLTSKLWKTEMGYDAALRAFDATLERLGTDYLDLYLIHWP---- 111
Query: 504 ENDTLLDNVDFLD--TWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 677
D L++ LD TWR + + GL ++IG+SNF ++ I+ S P Q+E
Sbjct: 112 RPDLELEDWAKLDRETWRALERLYESGLVRAIGVSNFLPHHLEPILASANVAPMVDQLEF 171
Query: 678 NLNLQQPELFKFCRENDIVVMAYTPFG 758
+ Q E FC+ + I+V A++P G
Sbjct: 172 HPGYTQDEAVAFCQNHSILVEAWSPLG 198
>UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2;
Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 281
Score = 113 bits (271), Expect = 7e-24
Identities = 78/210 (37%), Positives = 111/210 (52%), Gaps = 1/210 (0%)
Frame = +3
Query: 132 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVT-NDTEQAVIYALEAGYTHIDTAYKYGI 308
+P L L++G IP + G V QV +T++ V ALEAGY HIDTA Y
Sbjct: 9 IPQLTLNNGVKIPQLGFG----------VFQVPPEETQRIVEDALEAGYRHIDTAAAYRN 58
Query: 309 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 488
E VG A++ + G+ RE IFITTKL N E+ A + S + L +E+VDLYLIHW
Sbjct: 59 EAGVGAAIS---ASGIPREDIFITTKLRNG--EQGNAHEAFQNSRKALGVEFVDLYLIHW 113
Query: 489 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 668
P+ + L + + W+ M ++IG+SNF E + ++ + P+ Q
Sbjct: 114 PVP---SQGL-----YTEAWKAMEKLYANSQIRAIGVSNFLGEHLDTLLPAADVVPAVNQ 165
Query: 669 IELNLNLQQPELFKFCRENDIVVMAYTPFG 758
+E++ QQ EL CRE I V AY+P G
Sbjct: 166 VEIHPTFQQQELAAKCRELGIAVEAYSPLG 195
>UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;
n=6; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase B - Corynebacterium sp. (strain SHS752001)
Length = 277
Score = 113 bits (271), Expect = 7e-24
Identities = 68/207 (32%), Positives = 113/207 (54%)
Frame = +3
Query: 132 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 311
+PT+ L+ G LGT+ +G A++ A+++GY +DTA Y E
Sbjct: 4 IPTISLNDGRPFAEPGLGTYNLRGDEGVA---------AMVAAIDSGYRLLDTAVNYENE 54
Query: 312 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 491
+VGRA+ + + R+ + + +K+ H R + + ++R SL+ L L+ +DL LIHWP
Sbjct: 55 SEVGRAVR---ASSVDRDELIVASKIPGRQHGRAEAVDSIRGSLDRLGLDVIDLQLIHWP 111
Query: 492 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 671
N ++ +LDTWRGMIDA++ GL +SIG+SNF + ++ +ID P+ Q+
Sbjct: 112 -----NPSV---GRWLDTWRGMIDAREAGLVRSIGVSNFTEPMLKTLIDETGVTPAVNQV 163
Query: 672 ELNLNLQQPELFKFCRENDIVVMAYTP 752
EL+ Q L F E+ I +++P
Sbjct: 164 ELHPYFPQAALRAFHDEHGIRTESWSP 190
>UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 288
Score = 111 bits (268), Expect = 2e-23
Identities = 84/249 (33%), Positives = 118/249 (47%), Gaps = 2/249 (0%)
Frame = +3
Query: 135 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTND--TEQAVIYALEAGYTHIDTAYKYGI 308
PT+ L+ G IP + GT+ Q+ +D T QAV AL GY HIDTA Y
Sbjct: 5 PTITLNDGRAIPAIGFGTF----------QIPDDGSTYQAVKEALVIGYRHIDTAVAYFN 54
Query: 309 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 488
ED+VG+A+ G+ R+ I++T+KLW + + A+ +SL L L+Y+DLYLIH
Sbjct: 55 EDEVGQAIK---DSGIPRDQIWVTSKLWLQDYGFDAASRAIDRSLTKLRLDYIDLYLIHQ 111
Query: 489 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 668
P D W+ M A+K G KSIG+SN Q+ + P+ Q
Sbjct: 112 PYG-----------DVPGAWQAMEAAQKAGKLKSIGVSNMTPTLWQKFVPQFETIPAVNQ 160
Query: 669 IELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNK 848
+E N QQ L + D+ + A+ P G Q P I +A KY+K
Sbjct: 161 VEFNPYFQQQPLRQLLAAQDVKLEAWAPLG----QGNQALFKEPIIQQ-----LAIKYHK 211
Query: 849 TVPQVALRF 875
Q+ LRF
Sbjct: 212 DAGQIILRF 220
>UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Acinetobacter sp. (strain ADP1)
Length = 297
Score = 111 bits (268), Expect = 2e-23
Identities = 81/248 (32%), Positives = 127/248 (51%)
Frame = +3
Query: 132 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 311
+P L L G +IP + GT+ +G DT ++ AL GY +D+A+ Y E
Sbjct: 22 IPDLILHDGHSIPALGFGTYTLKGQQGV------DT---MLRALGHGYRMLDSAFNYENE 72
Query: 312 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 491
VG A+ + GL R+ IFIT+KL +H ++ + + +SL + +Y+DLYLIHWP
Sbjct: 73 GAVGAAVRQS---GLLRDEIFITSKLPGRHHAYDKAMETIEESLYRMQFDYLDLYLIHWP 129
Query: 492 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 671
+++ W+ +IDA+K G +SIG+SNF + I+ + P Q+
Sbjct: 130 NP--------QQGLYIEAWQALIDAQKKGYIRSIGVSNFLPKHIETLRRETGVIPVINQV 181
Query: 672 ELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKT 851
EL+ Q E + I+ MA++P G +KA +DD L IAQ+ ++T
Sbjct: 182 ELHPYFNQAEQRAYDESQQIITMAWSPLGR---AKA-------ILDDAVLKQIAQETSRT 231
Query: 852 VPQVALRF 875
V QV LR+
Sbjct: 232 VVQVVLRW 239
>UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:
Aldo/keto reductase - Kineococcus radiotolerans SRS30216
Length = 343
Score = 111 bits (268), Expect = 2e-23
Identities = 74/263 (28%), Positives = 125/263 (47%), Gaps = 14/263 (5%)
Frame = +3
Query: 129 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 308
+VP +L G +P + +GT+ R V AV A+ AGY +D A YG
Sbjct: 12 LVPRRELRGGATVPAIGIGTFGSDRYSPAEVAA------AVAGAVAAGYRLVDCAAVYGN 65
Query: 309 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 488
E QVG AL + G+ R+ +F+ +K+WN H + ++ +SL +L L+++D +HW
Sbjct: 66 EAQVGEALAGAVAGGVDRDELFVVSKVWNDAHAPADAVASVHRSLRDLRLDHLDAVFVHW 125
Query: 489 PI-----AMFENDTL------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII 635
P M + D D+ +L W + GL + +G SN ++ ++
Sbjct: 126 PFPNHHPPMADTDARDPRARPYDHDAYLALWGALEGLVDSGLVRHLGTSNTTVAKLDLLL 185
Query: 636 DSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRI--- 806
P+ ++EL+ QQPELF C + I + Y+P GS PS+ + P +
Sbjct: 186 RDARIPPALNEMELHPCFQQPELFAHCVRHGIQPVGYSPLGS--PSRPERDRTPGDVVDT 243
Query: 807 DDERLVGIAQKYNKTVPQVALRF 875
+D +V IA+++ V L++
Sbjct: 244 EDPVVVRIAREHGVHPALVCLKW 266
>UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 263
Score = 111 bits (268), Expect = 2e-23
Identities = 76/217 (35%), Positives = 115/217 (52%), Gaps = 3/217 (1%)
Frame = +3
Query: 234 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHERE 413
+ E A+ A++ GY +DTA Y E+ VG + K G+ R+ +FITTK+WN+
Sbjct: 16 EAEDAIAAAVQNGYRLLDTASAYKNEEFVGCGIAKC---GVPRKDLFITTKIWNNAQRLG 72
Query: 414 QVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSI 593
V A ++SL+ L L+Y+DLYLIHWP+ FL+TW+ M + G SI
Sbjct: 73 DVEGAFQRSLDRLGLDYIDLYLIHWPVPGC----------FLNTWKDMEKILESGRALSI 122
Query: 594 GISNF---NQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSL 764
G+SNF + E+++R+ SG+ P+ QIE + EL ++C+ NDI V AY P
Sbjct: 123 GVSNFEIRHLEELRRV--SGI-VPAVNQIECHPLCYPKELIEYCQANDIQVQAYAPL--- 176
Query: 765 FPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQVALRF 875
A +D++ L + KY T Q+ LR+
Sbjct: 177 --------ARGAYLDNDVLCVLGTKYAHTPAQIGLRW 205
>UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core
eudicotyledons|Rep: T2K10.1 protein - Arabidopsis
thaliana (Mouse-ear cress)
Length = 176
Score = 111 bits (268), Expect = 2e-23
Identities = 65/178 (36%), Positives = 103/178 (57%), Gaps = 14/178 (7%)
Frame = +3
Query: 132 VPTLQLSSGGN----IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYK 299
VPTL + SG + +PV+ GT P+ +++ T VI A++ GY H DT+ +
Sbjct: 6 VPTLAIRSGPSGHHSMPVLGFGTAASPLPEPTMLKET------VIEAIKLGYRHFDTSPR 59
Query: 300 YGIEDQVGRALTKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDL 473
Y E+ +G AL + S GL R F+TTKLW + V+PA+++SL+NL L+Y+DL
Sbjct: 60 YQTEEPIGEALAEAVSLGLVRSRSEFFVTTKLWCADAHGGLVVPAIKRSLKNLKLDYLDL 119
Query: 474 YLIHWPIAM--------FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQI 623
Y+IHWP++ + D + +DF W M + ++LGL K IG+SNF+ +++
Sbjct: 120 YIIHWPVSSKPGKYKFPIDEDDFMP-MDFEVVWSEMEECQRLGLAKCIGVSNFSCKKL 176
>UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 355
Score = 111 bits (268), Expect = 2e-23
Identities = 83/276 (30%), Positives = 135/276 (48%), Gaps = 32/276 (11%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQA----------VIYALEAGYTHI- 284
T +L++G IPV+ LGTW G+V + +A + L GY +
Sbjct: 13 TFKLNTGAEIPVIGLGTW--QSAPGEVAKAVESAIKAGYRHIVSMLTSLLTLTLGYVALH 70
Query: 285 ---------DTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRK 437
D A+ YG E++VG+ + + G+ R +F+TTK+W +YH + + L +
Sbjct: 71 PLYIPFLAKDAAWIYGNENEVGQGIK---ASGVPRSELFVTTKIWCTYHRQPEA--CLDE 125
Query: 438 SLENLNLEYVDLYLIHWPIAMFEN-DTLL----DNVDFLD-------TWRGMIDAKKLGL 581
SL+ L L+YVDL L+HWP+ + + D + D +D TW M G
Sbjct: 126 SLQRLGLDYVDLLLVHWPVPLVKRGDEKIPLNEDGSRAIDRDWSPEQTWELMEKLPATGK 185
Query: 582 TKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGS 761
TK+IG+SN++ + +++ P+A Q+EL+ L Q EL K+C + I+ AY+P GS
Sbjct: 186 TKAIGVSNWSIAFLDKLLAKAKIVPAANQVELHPFLPQHELVKYCHDKGILPQAYSPLGS 245
Query: 762 LFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQVAL 869
+ P + DER+ IA+ + QV +
Sbjct: 246 ---------SGGPVLQDERVQSIAKAHKADPAQVVI 272
>UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus
terreus NIH2624|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 292
Score = 111 bits (267), Expect = 2e-23
Identities = 80/248 (32%), Positives = 119/248 (47%), Gaps = 1/248 (0%)
Frame = +3
Query: 135 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 314
P L L G +P++ GT + + + ALE G+ HID A YG E
Sbjct: 4 PALSLKDGNLVPILGFGTGTAWYKDDPNDPTNPELIEVLKAALEKGFHHIDAADSYGTER 63
Query: 315 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
+VG A+ + G+ RE +FITTK+ + + V AL SLE L L+YVDLYL+H P
Sbjct: 64 EVGIAIRES---GIPREQLFITTKVLEGWKD---VPGALDASLERLQLDYVDLYLLHNPY 117
Query: 495 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 674
+ N T D W+G+ K G +SIG+SNF + ++ I+++ P+ Q+E
Sbjct: 118 VI-PNLT-----DIQSAWKGLEAVKATGKARSIGVSNFQRNHLEAILETCSVVPAINQLE 171
Query: 675 LNLNLQQP-ELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKT 851
+ LQ+ + + RE I V ++ + K P DE L IA K+N T
Sbjct: 172 YHPYLQRSHDFIPWMRERGIEVSSFKTLAPVTVGKGGPL-------DEPLASIAAKHNIT 224
Query: 852 VPQVALRF 875
V L +
Sbjct: 225 TSAVVLNW 232
>UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 274
Score = 111 bits (267), Expect = 2e-23
Identities = 81/241 (33%), Positives = 119/241 (49%), Gaps = 1/241 (0%)
Frame = +3
Query: 156 GGNIPVVALGTWLGHRPKGKVVQVTNDT-EQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 332
G ++P + LGTW Q+T + + V AL GY HIDTA YG E QVG +
Sbjct: 8 GTSVPALGLGTW----------QLTGQSCRETVETALGMGYRHIDTAQAYGNERQVGLGM 57
Query: 333 TKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEND 512
+ + RE +F+TTKL S + V + R+SL L +Y+DL LIHWP N
Sbjct: 58 D---AAAVDREDVFLTTKLDGSNRDERSVRRSTRESLNKLGTDYLDLLLIHWP-----NT 109
Query: 513 TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQ 692
+ ++ +T M D + GL + IG+SNF+ + R D Q++ +
Sbjct: 110 PWMASLS--ETLGAMNDVVEEGLVRHIGVSNFSPSLLDRARDISSAPIFTDQVQYHPYWD 167
Query: 693 QPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQVALR 872
Q +L +CR +D+++ AY+P A +DD LV I KY K+ QVALR
Sbjct: 168 QRKLLDYCRIHDVLLTAYSPL-----------ARGGVLDDPALVQIGNKYGKSPAQVALR 216
Query: 873 F 875
+
Sbjct: 217 W 217
>UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep:
Lin2739 protein - Listeria innocua
Length = 283
Score = 111 bits (266), Expect = 3e-23
Identities = 79/246 (32%), Positives = 121/246 (49%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
T++L++G +P++ GT+ + + EQAV A+ AGY HIDTA Y E+
Sbjct: 3 TVKLNNGIEVPILGFGTYQ--------ITDAGEAEQAVKEAIAAGYRHIDTAQSYMNEEA 54
Query: 318 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
VGR + + G+ R+ +FITTK+W + V+ + +SL+ L L+Y+DL LIH P
Sbjct: 55 VGRGIA---ASGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYIDLLLIHQPYN 111
Query: 498 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 677
D W M + + G K+IG+SNF +++ + P QIE+
Sbjct: 112 -----------DVYGAWMAMEELQAQGKIKAIGVSNFGVDRVVDLAAFNDITPQVNQIEI 160
Query: 678 NLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVP 857
N QQ + + R+ + V A+ PF K P L IA+KY K+V
Sbjct: 161 NPFQQQSKNIEALRKEGVAVEAWAPFAE---GKNDIFTNP------ILTKIAEKYGKSVA 211
Query: 858 QVALRF 875
QV LR+
Sbjct: 212 QVILRW 217
>UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;
n=91; Proteobacteria|Rep: 2,5-diketo-D-gluconic acid
reductase B - Yersinia pestis
Length = 267
Score = 111 bits (266), Expect = 3e-23
Identities = 73/196 (37%), Positives = 113/196 (57%), Gaps = 1/196 (0%)
Frame = +3
Query: 162 NIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKK 341
+IPV LGT+ R + ++V +V AL GY IDTA Y E VG+A+ +
Sbjct: 2 SIPVFGLGTF---RLQDQIVI------DSVSQALTLGYRAIDTAQIYENEAPVGQAIQES 52
Query: 342 FSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLL 521
G+ R+ +FITTK+W + ++++IP+LR+S++ L +YVDL LIHWP +
Sbjct: 53 ---GINRDELFITTKIWIANLSKDKLIPSLRESIQKLKTDYVDLTLIHWP-------SPN 102
Query: 522 DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLEKPSALQIELNLNLQQP 698
D V + ++ AK LGLT+ IGISNF + +++ I + G E+ + QIEL+ LQ
Sbjct: 103 DEVSVAEFMSELLKAKGLGLTRQIGISNFTIDLMKQAIAAVGAEEIATNQIELSPLLQNR 162
Query: 699 ELFKFCRENDIVVMAY 746
+ F ++N I V +Y
Sbjct: 163 NVVDFAKQNGIAVTSY 178
>UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase
family; n=2; Thermotoga|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 274
Score = 110 bits (265), Expect = 4e-23
Identities = 68/209 (32%), Positives = 115/209 (55%), Gaps = 9/209 (4%)
Frame = +3
Query: 153 SGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIY--ALEAGYTHIDTAYKYG---IED 314
+G IP + LGTW +G + + D E + A++ GYTHIDTA YG E+
Sbjct: 9 TGEEIPALGLGTWGIGGF---ETPDYSRDEEMVELLKTAIKMGYTHIDTAEYYGGGHTEE 65
Query: 315 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
+G+A+ K F +RE +FI +K+W ++ R+ ++ +L +L+ L+ +YVDLYLIHWP
Sbjct: 66 LIGKAI-KDF----RREDLFIVSKVWPTHLRRDDLLRSLENTLKRLDTDYVDLYLIHWP- 119
Query: 495 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 674
+ +T M + + GL + IG+SNF++ ++ I E Q++
Sbjct: 120 --------NPEIPLEETLSAMAEGVRQGLIRYIGVSNFDRRLLEEAISKSQEPIVCDQVK 171
Query: 675 LNLNLQQPE---LFKFCRENDIVVMAYTP 752
N+ + PE L +FC++N + ++AY+P
Sbjct: 172 YNIEDRDPERDGLLEFCQKNGVTLVAYSP 200
>UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep:
Oxidoreductase - Bradyrhizobium japonicum
Length = 272
Score = 110 bits (264), Expect = 5e-23
Identities = 76/244 (31%), Positives = 124/244 (50%), Gaps = 2/244 (0%)
Frame = +3
Query: 150 SSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 326
++G IP + LGTW L RP +VV+ AL GY HIDTA Y E +VG
Sbjct: 6 ANGARIPAIGLGTWELSGRPCARVVE----------QALRLGYRHIDTAQVYDNEREVGD 55
Query: 327 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 506
+ + G++R+ +F+TTK+W ++ + ++++SL L L VDL L+HWP +
Sbjct: 56 GVR---ASGVRRDDVFLTTKVWTNHFAPNDLERSVKESLARLRLPSVDLLLLHWPNS--- 109
Query: 507 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLN 686
+V +T + A+++GLT+ IG+SNF I++ + E Q+E +
Sbjct: 110 ------HVPLAETLGALSHARQMGLTRHIGVSNFTVALIEQAVALSPEPLVCNQVEFHPY 163
Query: 687 LQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRI-DDERLVGIAQKYNKTVPQV 863
L Q ++ C ++ + ++AY+P RI D+ L GI + + KT QV
Sbjct: 164 LDQAKVRAACDQHGLALVAYSPIAR------------GRIKTDQTLAGIGRAHRKTPAQV 211
Query: 864 ALRF 875
LR+
Sbjct: 212 CLRW 215
>UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1
protein.; n=1; Takifugu rubripes|Rep: Homolog of Homo
sapiens "AKR1B1 protein. - Takifugu rubripes
Length = 330
Score = 109 bits (261), Expect = 1e-22
Identities = 97/287 (33%), Positives = 139/287 (48%), Gaps = 38/287 (13%)
Frame = +3
Query: 129 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 308
++P++ L++G +PV+ LGTW GK V T +AV A+ AGY HIDTAY Y
Sbjct: 1 MIPSVTLNTGALMPVLGLGTW----KSGKGV-----TTEAVKVAIGAGYRHIDTAYVYEN 51
Query: 309 EDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 485
E +VG + +G+ KRE +FI +KLW ++H V A K+L +LNL+YVDLYL+H
Sbjct: 52 ETEVGAGVQAMIDQGVVKREELFIVSKLWCTFHTPSLVRGACEKTLSSLNLDYVDLYLMH 111
Query: 486 WPI----AMFENDTLLDNV-----DFLDTWRGMIDAKKLGLTKSI---GISNFNQ-EQIQ 626
+P+ A + +L D + DF G D L + G S + E ++
Sbjct: 112 FPMGALSATLDLTSLTDVIPTVFRDFSPLQPGE-DPFPLDEHNQLICDGTSFLDTWEAME 170
Query: 627 RIIDSGLEKPSAL------QIELNLN------------------LQQPELFKFCRENDIV 734
++D GL K + QIE LN L Q +L FCR I
Sbjct: 171 ELVDDGLAKAIGISNFNKDQIEAVLNKPGLKHKPATNQIECHPHLNQEKLIHFCRSRGIS 230
Query: 735 VMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQVALRF 875
V A+ GS S A P +DD ++ IA+K T QV ++F
Sbjct: 231 VTAFACLGSADRSWASAD-EPSFLDDPQINAIARKNQMTPAQVLIKF 276
>UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 287
Score = 108 bits (260), Expect = 2e-22
Identities = 83/248 (33%), Positives = 124/248 (50%), Gaps = 5/248 (2%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 326
L +G IP +G +L + T V AL+ GY IDTA +Y E + G
Sbjct: 12 LLNGSRIPACGVGVYL---------LPASQTAGIVEKALDVGYRLIDTAQEYENERETGE 62
Query: 327 ALTKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLENL-NLEYVDLYLIHWPIA 497
+ + KRE + TTK+ N ++ +L++SL + +LEY+DL LIH
Sbjct: 63 GIKAWLGKDKNNKREDVLYTTKITNLNQGYDRTWRSLKESLNKVKHLEYIDLVLIH---- 118
Query: 498 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID-SGLE-KPSALQI 671
D L D ++TW+ + +A G+ KSIG+SNF + IQ + D GL+ KP QI
Sbjct: 119 ----DPLSDKKTRIETWKALQEAVDSGMVKSIGVSNFGKHHIQELYDWEGLKYKPIVNQI 174
Query: 672 ELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKT 851
EL+ L + +L +C+ IV+ AY P +++D LV +A+KYNKT
Sbjct: 175 ELSPWLMRKDLVDYCQNLGIVLEAYCPL-----------TTGAKLNDPTLVKLAKKYNKT 223
Query: 852 VPQVALRF 875
QV LR+
Sbjct: 224 PAQVLLRW 231
>UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter
cryohalolentis K5|Rep: Aldo/keto reductase -
Psychrobacter cryohalolentis (strain K5)
Length = 282
Score = 107 bits (257), Expect = 4e-22
Identities = 75/219 (34%), Positives = 120/219 (54%), Gaps = 7/219 (3%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
++ + NIPV+ LGTW + G+ D V L GY HIDTA YG E +V
Sbjct: 8 IRTAGQANIPVLGLGTW---QSTGQ------DCIDVVSQGLRMGYEHIDTAQAYGNEVEV 58
Query: 321 GRALTKKFSEGLKRESIFITTKLW--NSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
G+ + + G+ R+ F+TTK++ + E E+++ A ++SLENL+ +YVDL L+HWP
Sbjct: 59 GKGIKQS---GVARDKFFLTTKIFPDDMKFEPEKLVAAAKRSLENLDTDYVDLLLLHWPD 115
Query: 495 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSG--LEKPSAL- 665
D V +T + + +K GLT++IG+SNFN I II++ + P +
Sbjct: 116 ---------DRVPLSETIPALCELQKQGLTRNIGVSNFN---IANIIEAKRYADVPIVVN 163
Query: 666 QIELNLNLQQPELFKFCRENDIVVMAYTPF--GSLFPSK 776
Q+E + ++Q L F + I++ AY+P G +F +K
Sbjct: 164 QVEFHPFIKQKTLQTFLNNHHILLEAYSPLARGDVFDNK 202
>UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium
sp. BNC1|Rep: Aldo/keto reductase - Mesorhizobium sp.
(strain BNC1)
Length = 253
Score = 107 bits (257), Expect = 4e-22
Identities = 77/237 (32%), Positives = 121/237 (51%)
Frame = +3
Query: 165 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF 344
+P++ LGTW Q+T++T + V A + GY +DT+ YG + +G A+
Sbjct: 1 MPILGLGTW----------QLTHETARTVRAAFDLGYRMVDTSGDYGTQSAIGEAIR--- 47
Query: 345 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLD 524
+ GL R+ I++ TK+ E E A + +L L L+Y DL LIH P + L
Sbjct: 48 ASGLDRDDIYLVTKV----EETEDAYNATQANLRELGLDYADLILIHRPPRHGAGEEL-- 101
Query: 525 NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPEL 704
WR +I A++ GLT+ IG+SN++ E I+ ++D+ E P Q+E + EL
Sbjct: 102 -------WRALIRAREDGLTRDIGVSNYSIELIEELVDATGEIPVVNQVEWSPFGHDLEL 154
Query: 705 FKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQVALRF 875
+ N IV+ AY+P ++A R+DD L A+KY KT QV +R+
Sbjct: 155 KHYADFNGIVIQAYSPL-----TRA------TRLDDAALCETAEKYGKTPAQVLIRW 200
>UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 264
Score = 107 bits (256), Expect = 5e-22
Identities = 69/220 (31%), Positives = 116/220 (52%)
Frame = +3
Query: 216 VVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWN 395
V ++ E ++AL+ GY +DTA Y E +VG A+ K GLKRE I++TTKL
Sbjct: 28 VFRLETGCEDVCLFALKNGYRMLDTADIYQNEKEVGSAVRKS---GLKREDIYVTTKLKP 84
Query: 396 SYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKL 575
S + ++S++ L++ YVDL+LIH P N+ + + ++ K+
Sbjct: 85 SEEGHSNALKYAKESIKKLDIGYVDLFLIHTPRP--------GNI--IAAYDALLTLKEE 134
Query: 576 GLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPF 755
GL +S+G+SNF ++ + +G P+ QIE+N +Q E+ K+C ++ I V Y P
Sbjct: 135 GLIRSVGVSNFGVHHLEELRKAGCRTPAINQIEINPFWRQEEIIKYCNKHGITVEGYAP- 193
Query: 756 GSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQVALRF 875
+F + D LV ++++Y KTV Q+ +R+
Sbjct: 194 --VFRG--------CKFDHPVLVEMSERYGKTVAQIMIRW 223
>UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1;
Candida parapsilosis|Rep: Conjugated polyketone
reductase C2 - Candida parapsilosis (Yeast)
Length = 307
Score = 107 bits (256), Expect = 5e-22
Identities = 79/263 (30%), Positives = 126/263 (47%), Gaps = 9/263 (3%)
Frame = +3
Query: 114 TSADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTA 293
T ++L+ T + SG I + ALGT + + V+ + ++ L+ G+ HIDTA
Sbjct: 2 TQSNLLPKTFRTKSGKEISI-ALGTGTKWKQAQTINDVSTELVDNILLGLKLGFRHIDTA 60
Query: 294 YKYGIEDQVGRALTKKFSEGLKRESIFITTKL---WNSYHE-REQVIPALRKSLENLNLE 461
Y + +VG AL + + RE I++TTK W S + ++ K+L L ++
Sbjct: 61 EAYNTQKEVGEALKR---TDVPREDIWVTTKYSPGWGSIKAYSKSPSDSIDKALAQLGVD 117
Query: 462 YVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS 641
YVDL+LIH P E W +++AKK G + IGISN ++++ +
Sbjct: 118 YVDLFLIHSPFFTTEQ---THGYTLEQAWEALVEAKKAGKVREIGISNAAIPHLEKLFAA 174
Query: 642 GLEK---PSALQIELN--LNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRI 806
P QIE + L Q + +FC+E+ I+V A++P L + A
Sbjct: 175 SPSPEYYPVVNQIEFHPFLQNQSKNIVRFCQEHGILVEAFSPLAPLARVETNALA----- 229
Query: 807 DDERLVGIAQKYNKTVPQVALRF 875
E L +A+KY KT QV LR+
Sbjct: 230 --ETLKRLAEKYKKTEAQVLLRY 250
>UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Arthrobacter sp. (strain FB24)
Length = 291
Score = 106 bits (255), Expect = 6e-22
Identities = 67/189 (35%), Positives = 97/189 (51%), Gaps = 14/189 (7%)
Frame = +3
Query: 234 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL--------------TKKFSEGLKRESI 371
D V ALEAGY H DTA YG E VG+A+ + + + L RE +
Sbjct: 29 DAAGLVTMALEAGYRHFDTAAMYGNETGVGKAIGALAGFAGGGPAGGSGEAAPSLSREDL 88
Query: 372 FITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWR 551
F+TTK+WN H + + A S+ NL +EYVDLYLIHWP A F +++R
Sbjct: 89 FVTTKVWNDDHGYDATMRAFDTSMSNLGMEYVDLYLIHWPCAR--------RGLFTESYR 140
Query: 552 GMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDI 731
M + G ++IG+SNF ++ ++++ P+ QIEL+ LQQ EL + I
Sbjct: 141 AMETLYREGRIRAIGVSNFQPAHLEHLLETAEVVPAVNQIELHPWLQQDELRQLHDRLGI 200
Query: 732 VVMAYTPFG 758
A++P G
Sbjct: 201 RTEAWSPLG 209
>UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reductase
family protein; n=3; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 299
Score = 106 bits (254), Expect = 9e-22
Identities = 81/255 (31%), Positives = 123/255 (48%), Gaps = 2/255 (0%)
Frame = +3
Query: 117 SADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAY 296
S+ I + LS+G +P LG+ VQ + + AL+ GY HIDTA
Sbjct: 2 SSQEIQKVITLSNGQKMPAFGLGS--------SRVQSVEEVTNLIRKALDVGYRHIDTAQ 53
Query: 297 KYGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDL 473
Y E +G AL F EG KRE IF+ TK + + + +++ L+ L ++YVDL
Sbjct: 54 MYENEQFIGAALKTIFGEGKYKREDIFLVTK--QASIKGVSCLEIMKEQLQKLQVDYVDL 111
Query: 474 YLIHWPIAMFEND-TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 650
LIH P+A +D ++ W + LGL K +G+SNFN + I ++
Sbjct: 112 LLIHVPLAAPSDDYQQWNHKPVHQIWAEFEEIHSLGLAKGLGVSNFNCQMIIDLLAYCKI 171
Query: 651 KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGI 830
KP QIEL++ QQ L +F ++ +I +A++P + +E L I
Sbjct: 172 KPLVNQIELHVFNQQKNLVEFLKKVNIYPVAFSPMAKY----------NEVVKNETLNQI 221
Query: 831 AQKYNKTVPQVALRF 875
AQK N +V QV + F
Sbjct: 222 AQKQNASVAQVMIAF 236
>UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Escherichia coli (strain UTI89 / UPEC)
Length = 294
Score = 106 bits (254), Expect = 9e-22
Identities = 75/224 (33%), Positives = 112/224 (50%), Gaps = 4/224 (1%)
Frame = +3
Query: 216 VVQVTNDT--EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL-KRESIFITTK 386
V QVT+ +Q+V+ A+ GY IDTA YG ED VG A+ + SEGL RE +FIT+K
Sbjct: 24 VFQVTDKDVCKQSVLNAIRTGYRLIDTAAVYGNEDAVGEAVREAISEGLCTREELFITSK 83
Query: 387 LWNSYHEREQVIPA-LRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMID 563
LW + + A + SL+ LEY DLYL+H + D+ WR + D
Sbjct: 84 LWVQDMLNQDIAAAGIEASLKKSGLEYFDLYLLHQAMR-----------DYFSAWRALED 132
Query: 564 AKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMA 743
A + G K+IG+SNF + ++ KP Q+EL+ QPE + ++ A
Sbjct: 133 AYEEGKLKAIGVSNFYPHVLANFCETVRVKPMVNQVELHPYFAQPEALATMKYYNVQPEA 192
Query: 744 YTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQVALRF 875
+ P G + +P ++ L IA + K++ QV LR+
Sbjct: 193 WAPLGG---GRHKP------FENNLLQSIADAHQKSISQVILRW 227
>UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 324
Score = 105 bits (253), Expect = 1e-21
Identities = 70/221 (31%), Positives = 115/221 (52%), Gaps = 11/221 (4%)
Frame = +3
Query: 240 EQAVIYALEAGYTHIDTAYKYG---IEDQVGRALTKKFSEGLKRESIFITTKLWNSYHER 410
+ +V++AL+ GY HID A YG +E +G A+ + G+ RE +F+ TKL N +H
Sbjct: 37 KDSVLHALKIGYRHIDAALAYGWGSVERGIGAAIR---ASGVPREDVFVVTKLHNCFHAP 93
Query: 411 EQVIPALRKSLENLNLEYVDLYLI----HWPIAMFENDTLLD---NVDFLDTWRGMIDAK 569
E V + SL+NL L YV + + + ++D + F TW+ M +
Sbjct: 94 EDVEVGMNMSLKNLGLGYVPYAYTKGENYSTVRKPDGKPVVDIELSRAFDTTWKAMENLV 153
Query: 570 KLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYT 749
G K IG+SNF+ +++R++ P Q+ELN Q +L +FC E++I V AY
Sbjct: 154 DQGKAKLIGVSNFSTPKLKRLLSVCRIFPVVNQVELNPYFPQKQLLRFCHEHEIHVTAYG 213
Query: 750 PFG-SLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQVAL 869
P G + P P P ++D + +A++Y++T Q+ L
Sbjct: 214 PLGCTPVPYLIGRKTPGP-LEDCTVKAMAERYSRTPAQIIL 253
>UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 313
Score = 105 bits (253), Expect = 1e-21
Identities = 82/249 (32%), Positives = 120/249 (48%), Gaps = 6/249 (2%)
Frame = +3
Query: 147 LSSGGNIP---VVALGTWLGHRPKGKVVQVTNDTEQAVIYALEA-GYTHIDTAYKYGIED 314
L++G IP ++ GT RP G +++ + + YAL G HID A YG
Sbjct: 10 LNNGNQIPSISIIGTGTRWFKRP-GSEHTFSDELVEQIKYALSLPGIIHIDAAECYGTYP 68
Query: 315 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
++ +AL K+ S+ R IFIT K I L L+ L L+YVDLYLIH P
Sbjct: 69 ELAKAL-KESSK--PRSEIFITDKYSTQTKFTNDPIEGLNTGLKTLGLDYVDLYLIHSP- 124
Query: 495 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 674
F + ++ W+ M K G KSIG+SNF+ + I+ I+ KP QIE
Sbjct: 125 --FFDPEFKGSLTLEKVWKDMETLYKEGKAKSIGVSNFSVKNIEEILKIAGIKPQVNQIE 182
Query: 675 LN--LNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNK 848
N L Q P + +C++N+I + AY+P G P + +P + +A KY K
Sbjct: 183 FNAFLQNQTPGIVNYCQKNNIQLEAYSPLG---PLQKRPENSNELPFYNYIDELASKYGK 239
Query: 849 TVPQVALRF 875
T Q+ L +
Sbjct: 240 TDSQILLNW 248
>UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Shewanella sp. (strain ANA-3)
Length = 280
Score = 105 bits (252), Expect = 1e-21
Identities = 73/214 (34%), Positives = 109/214 (50%), Gaps = 1/214 (0%)
Frame = +3
Query: 231 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHER 410
N AV+ ALE G HIDTA YG E VG A+ + G+ RE +FITTK+W +
Sbjct: 30 NAAFDAVLMALEEGSRHIDTAQIYGNEQAVGDAIN---TSGIPREELFITTKVWTENLTK 86
Query: 411 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 590
E+ ++ SL L +Y+DL LIHWP+ N V++L + ++D GLT+
Sbjct: 87 ERFETSVIDSLTALQTKYLDLLLIHWPL----NSDEPSMVEYLSELKAVLDK---GLTRR 139
Query: 591 IGISNFNQEQI-QRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLF 767
IG+SNF Q+ Q I G Q+E++ L ++ FCR+++++V Y PF
Sbjct: 140 IGVSNFTNAQLAQAIAILGEGVIYTNQVEVHPYLINRKVTDFCRQHNVLVTGYMPF---- 195
Query: 768 PSKAQPXAPPPRIDDERLVGIAQKYNKTVPQVAL 869
A + DE +V +A + T Q+ L
Sbjct: 196 -------AYGAVLQDETIVNLASVHQATPAQIVL 222
>UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2;
Filobasidiella neoformans|Rep: Aldo-keto reductase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 293
Score = 105 bits (252), Expect = 1e-21
Identities = 81/253 (32%), Positives = 126/253 (49%), Gaps = 7/253 (2%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
T++L+SG IP + G + + + E AV A++ GY H+DTA Y E+
Sbjct: 8 TIKLASGNLIPRLGFGVYQAR---------SKECEDAVKKAIDTGYRHVDTAQAYHNEEN 58
Query: 318 VGRALTKKFSEGLKRESIFITTKLWNSY--HEREQVIPALRKSLENL-----NLEYVDLY 476
VGRA+ + G+ R S+F+T+K S+ + +V+ +RKSL+ + + Y+DL
Sbjct: 59 VGRAIR---NSGVPRPSVFLTSKYMPSHTVYSPTEVLDVVRKSLKKVDRCGDDKPYIDLM 115
Query: 477 LIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKP 656
LIH P E + W + A+K G K IG+SNF ++ + P
Sbjct: 116 LIHAPWGGEEGRK--------NNWEALTIAQKEGWVKDIGVSNFGIHHLKALPP---PVP 164
Query: 657 SALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQ 836
+ QIEL+ QQ ++ K+C E+ I + AY+P A D+E LV +A+
Sbjct: 165 AVNQIELHPFCQQRDIVKYCEEHGIAIEAYSPL---------VRANKKHYDNEVLVKVAK 215
Query: 837 KYNKTVPQVALRF 875
KY K V QV LR+
Sbjct: 216 KYGKEVAQVLLRW 228
>UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Aldo/keto reductase -
Halorubrum lacusprofundi ATCC 49239
Length = 309
Score = 105 bits (252), Expect = 1e-21
Identities = 79/249 (31%), Positives = 122/249 (48%), Gaps = 1/249 (0%)
Frame = +3
Query: 132 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 311
+PT L SG +P + LGT+ + +V AL +GYTHIDTA Y E
Sbjct: 34 IPTQTLPSGDTLPALGLGTY---------ALDDDQIADSVRAALSSGYTHIDTAEGYHNE 84
Query: 312 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 491
+ +G L + R+ +F+T+K+ E +I + SLE L +Y+DLYLIHWP
Sbjct: 85 EAIGEVLAE-----YDRDDVFLTSKVLAKNLGYESLIQSCEASLERLETDYLDLYLIHWP 139
Query: 492 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL-Q 668
N + ++ + M + GL +++G+SNF+ Q+ + E P A+ Q
Sbjct: 140 -----NPA----ISLRESLQAMAELHDRGLVRNVGVSNFSAYQLS-CANHISEVPIAVNQ 189
Query: 669 IELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNK 848
IE + Q+P L +C E+D V+ A A P A DDE + +A+ Y+K
Sbjct: 190 IEFHPWFQRPNLVDYCHESDTVIEA-----------AAPLARTEVFDDEVVAELAESYDK 238
Query: 849 TVPQVALRF 875
+ QV LR+
Sbjct: 239 SPAQVILRW 247
>UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1;
Candidatus Kuenenia stuttgartiensis|Rep: Putative
uncharacterized protein - Candidatus Kuenenia
stuttgartiensis
Length = 284
Score = 105 bits (251), Expect = 2e-21
Identities = 86/258 (33%), Positives = 134/258 (51%), Gaps = 15/258 (5%)
Frame = +3
Query: 147 LSSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQ--AVIYALEAGYTHIDTAYKYG---I 308
LS+ IPV+ LGTW +G G T D E A+ A++ G THID A Y
Sbjct: 6 LSNNIKIPVIGLGTWTIGG---GDEADTTYDKENISAIKTAIKLGITHIDNAEAYAQGHS 62
Query: 309 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 488
E+ VGRA+ GL R+S+FIT+K+ + + ++ + + SL+ LN +Y+DLYLIH
Sbjct: 63 EELVGRAIV-----GLDRKSLFITSKVSPEHLSYDNLLASAKGSLQRLNTDYIDLYLIHA 117
Query: 489 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 668
P + +DFL ++ K L + IG+SNF+ +QI+ K A Q
Sbjct: 118 PNPDIPIQETMKAMDFL------VEQK---LVRCIGVSNFSVDQIKEAQKYTKNKIVANQ 168
Query: 669 IELNLNLQ---------QPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERL 821
IE NL ++ + E+ +C+EN+I ++A+ P +K + P +I DE
Sbjct: 169 IEYNLLVRDKGRVTENMESEIIPYCQENNIFIIAWRPL-----AKGKLAKPGFKILDE-- 221
Query: 822 VGIAQKYNKTVPQVALRF 875
+A KY+KT Q+A+ +
Sbjct: 222 --LADKYHKTQAQIAINW 237
>UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep:
Lin2349 protein - Listeria innocua
Length = 294
Score = 104 bits (250), Expect = 3e-21
Identities = 61/169 (36%), Positives = 92/169 (54%)
Frame = +3
Query: 246 AVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIP 425
AV A+E GY DTA Y E VG+A+ + RE +FI++K+WN ++ +
Sbjct: 36 AVEKAIEVGYRLFDTAAVYNNEAIVGQAI---LDSAVPREELFISSKVWNGDLGYDETLF 92
Query: 426 ALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISN 605
A ++L NL L+Y+DLYLIHWP+A + D+WR M L KSIG++N
Sbjct: 93 AFERTLRNLKLDYLDLYLIHWPVA----------GKYRDSWRAMERLHDEKLIKSIGVAN 142
Query: 606 FNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTP 752
F Q + ++ + EKP Q+E + L Q +L K+ E +I A++P
Sbjct: 143 FKQHHLSDLLVAANEKPVLNQVETHPLLPQNDLRKYLAEQNIAHAAWSP 191
>UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1;
Parvularcula bermudensis HTCC2503|Rep: Putative
uncharacterized protein - Parvularcula bermudensis
HTCC2503
Length = 278
Score = 104 bits (250), Expect = 3e-21
Identities = 76/237 (32%), Positives = 122/237 (51%)
Frame = +3
Query: 165 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF 344
IP + GTW + +G+ + + T A+E GY HID A Y E +VG +
Sbjct: 11 IPRLGFGTW---QLEGEDARTSTRT------AIETGYRHIDGAAIYKNEKKVGEGIK--- 58
Query: 345 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLD 524
G+ R+ +F+TTK+WN ++ + A+ +SL+ L L+YV+L L+HWPI ND
Sbjct: 59 DSGIPRDELFVTTKIWNEDIQKGRHSEAVDESLDRLGLDYVNLILLHWPI----ND---- 110
Query: 525 NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPEL 704
+ D + + K+ G K IGISN+NQ Q + + E +A+Q E + L Q +
Sbjct: 111 -MPIADQVGPLAEIKRSGRAKLIGISNYNQAQFLEAVSASEEPLAAIQCEYHPMLDQDPI 169
Query: 705 FKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQVALRF 875
K R D++ +Y+P G + + + P ERL A+++ KT Q+ LR+
Sbjct: 170 LKTARGFDMMFTSYSPLG-----RGEAMSNPA---IERL---AEQHGKTPAQIILRW 215
>UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep:
Aldo/keto reductase - Mesorhizobium sp. (strain BNC1)
Length = 308
Score = 104 bits (249), Expect = 3e-21
Identities = 67/215 (31%), Positives = 111/215 (51%)
Frame = +3
Query: 231 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHER 410
++T AV AL GY HIDTA YG E +VG + + G+ R+ +FI TK+W S +
Sbjct: 42 DETTAAVEEALRLGYRHIDTAAAYGNEREVGEGIRRA---GIARDEVFIETKIWISDYGY 98
Query: 411 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 590
++ + A KS L ++ +DL L+H P+ + T L +R + G ++
Sbjct: 99 DETLHAFDKSAGKLGVDQIDLLLLHQPLPSAFDRT-------LGAYRALEKLLADGKVRA 151
Query: 591 IGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFP 770
IG+SNF E + R++ P+ QIE++ QQ L + E+ I+ A++P G +
Sbjct: 152 IGVSNFMPEHLTRLLTETSIVPAVNQIEVHPYFQQRALQRLHAEHGILTQAWSPIGGITF 211
Query: 771 SKAQPXAPPPRIDDERLVGIAQKYNKTVPQVALRF 875
+ ++D L+ IAQ++ K+ QV LR+
Sbjct: 212 YRG---GEKSTLEDPVLLEIAQQHGKSAAQVMLRW 243
>UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldehyde
reductase AKR3C2; n=1; Schizosaccharomyces pombe|Rep:
NADH/NADPH dependent indole-3-acetaldehyde reductase
AKR3C2 - Schizosaccharomyces pombe (Fission yeast)
Length = 284
Score = 104 bits (249), Expect = 3e-21
Identities = 67/211 (31%), Positives = 105/211 (49%), Gaps = 2/211 (0%)
Frame = +3
Query: 165 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF 344
+P +GT L + KG++ + D+ V AL AG+ HID A YG E++VG AL +
Sbjct: 12 VPAYGVGTALFKKEKGEINRTIVDS---VKNALAAGFIHIDCAEVYGNEEEVGVALKEA- 67
Query: 345 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLD 524
+ R +FIT+K+ H + + AL +SL L +Y+DLYL+H PI +E
Sbjct: 68 --NVPRSKLFITSKVM---HNVDNIPEALNESLRKLGTDYLDLYLLHSPIPFYEK----- 117
Query: 525 NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQ--P 698
+ + W+ M A GL S+G+SNF ++ ++ + P QIE + + +
Sbjct: 118 KIPISEGWKAMETALGTGLVHSVGVSNFRIPDLEELLKTSTITPRVNQIEFHPQVYKAAK 177
Query: 699 ELFKFCRENDIVVMAYTPFGSLFPSKAQPXA 791
L +FC+ I+V Y P L P A
Sbjct: 178 PLVEFCQSKGIIVEGYGPLSPLVRDAQGPVA 208
>UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1;
Actinobacillus succinogenes 130Z|Rep: Aldo/keto
reductase precursor - Actinobacillus succinogenes 130Z
Length = 315
Score = 103 bits (248), Expect = 5e-21
Identities = 75/246 (30%), Positives = 123/246 (50%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
T++L++G +P++ +G W TE++V AL+AGY IDTA Y E
Sbjct: 44 TVKLNNGIEMPIIGIGVW---------TLTPEQTEKSVGEALKAGYRLIDTARMYRNEQA 94
Query: 318 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
VGRA+ G+ RE IFITTK++ S + A+ + L L+ +Y+DL L+H+P
Sbjct: 95 VGRAVR---DSGIPREEIFITTKIYGS-GDYANAEAAINERLRLLDTDYIDLLLLHYPD- 149
Query: 498 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 677
+NDT W+ M K G ++IG+SN++++ RI+ + P+ +Q E+
Sbjct: 150 --QNDT--------KAWKVMEQFVKAGKIRAIGLSNYHRKTFNRIMQAATITPAVVQNEV 199
Query: 678 NLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVP 857
++ Q + F R + A+ P G + D +V +A+KY K+
Sbjct: 200 HIYNQDKQTKAFLRNYGTQMEAWYPLGG--RNSYGNGGKDVLFADPTIVSLAKKYAKSPA 257
Query: 858 QVALRF 875
QV LR+
Sbjct: 258 QVLLRW 263
>UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1;
Clostridium beijerinckii NCIMB 8052|Rep:
2,5-didehydrogluconate reductase - Clostridium
beijerinckii NCIMB 8052
Length = 289
Score = 103 bits (248), Expect = 5e-21
Identities = 79/251 (31%), Positives = 125/251 (49%)
Frame = +3
Query: 123 DLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKY 302
+LI ++ +G IP V G + + KG+ D E AV A++ GY H DTA Y
Sbjct: 2 NLINKEIKAVNGIKIPQVGFGVYKLN--KGE------DFETAVGEAIKIGYRHFDTAKIY 53
Query: 303 GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 482
G E +G A+ K + RE FIT+K+WN+ H E A ++ + LN+EY+D+YLI
Sbjct: 54 GNEKDLGLAIEKS---QIPREEFFITSKVWNTDHGYEATKKAFEQTCKKLNVEYLDMYLI 110
Query: 483 HWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 662
H+ + +L+TW M + G K IG++NF + ++ ++ P
Sbjct: 111 HFASSY-----------YLETWHAMEELYLQGKIKVIGVANFQIQHLEELMKHSRITPMI 159
Query: 663 LQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKY 842
QIE + Q EL ++ ++ I+ A+ P G +KA +++ L IA +
Sbjct: 160 NQIETHPEFPQNELHQYLTKHKILHEAWAPLGQ--GNKA-------LLENTVLKKIASNH 210
Query: 843 NKTVPQVALRF 875
KTV QV LR+
Sbjct: 211 EKTVAQVILRW 221
>UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein;
n=1; Thermoplasma acidophilum|Rep: Alcohol dehydrogenase
related protein - Thermoplasma acidophilum
Length = 284
Score = 103 bits (248), Expect = 5e-21
Identities = 77/248 (31%), Positives = 127/248 (51%), Gaps = 7/248 (2%)
Frame = +3
Query: 153 SGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 332
+G + V+ +GTW + + V+ ++ YAL+ G IDTA YG ED VG A+
Sbjct: 12 TGRKVSVIGVGTWSLEGSRSENVR-------SIRYALDHGVNFIDTAEMYGTEDIVGEAI 64
Query: 333 TKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEND 512
+G +RE +FI TK+W ++ V+ + +SL+ L +YVDLY +HWP
Sbjct: 65 -----KGYRREDLFIATKVWPTHFAYHDVLKSCEESLKKLGTDYVDLYQLHWP------- 112
Query: 513 TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL--QIELNLN 686
+V +T M G + IGISNF+ ++++ + S L K + Q+E N+
Sbjct: 113 --NPSVSIKETMSAMEKLVDEGRIRYIGISNFSVKEMKEAM-SALAKYRIVSNQLEYNVA 169
Query: 687 LQQPE---LFKFCRENDIVVMAYTPF--GSLFPSKAQPXAPPPRIDDERLVGIAQKYNKT 851
++ E ++ FCR+N + ++AY+P G +F ++ + E L I +KY K
Sbjct: 170 TREIEDEGIYDFCRKNGMAIIAYSPLSHGKIFGNE---------MILETLTDIGKKYGKR 220
Query: 852 VPQVALRF 875
QVAL +
Sbjct: 221 PAQVALNW 228
>UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep:
Lmo2592 protein - Listeria monocytogenes
Length = 283
Score = 103 bits (247), Expect = 6e-21
Identities = 75/248 (30%), Positives = 120/248 (48%), Gaps = 2/248 (0%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTN--DTEQAVIYALEAGYTHIDTAYKYGIE 311
T++L++G +P++ GT+ Q+T+ + E AV A++AGY HIDTA Y E
Sbjct: 3 TVKLNNGVEVPILGFGTY----------QITDAAEAEHAVKDAIKAGYRHIDTAQSYMNE 52
Query: 312 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 491
+ VGR + + G+ R+ +FITTK+W + V+ + +SL+ L L+YVDL LIH P
Sbjct: 53 EAVGRGIA---ASGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYVDLLLIHQP 109
Query: 492 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 671
D W M + + G ++IG+SNF+ +++ + P QI
Sbjct: 110 FN-----------DVYGAWIAMEELQASGKIRAIGVSNFSPDRVIDLAAFNEVTPQVNQI 158
Query: 672 ELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKT 851
E+N QQ R+ + + A+ PF ++ L I KY K+
Sbjct: 159 EVNPFQQQTANLAILRKEGVAIEAWAPFAE---------GKNDIFNNPVLTKIGAKYGKS 209
Query: 852 VPQVALRF 875
QV LR+
Sbjct: 210 AAQVILRW 217
>UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma
penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
Length = 285
Score = 103 bits (247), Expect = 6e-21
Identities = 79/249 (31%), Positives = 130/249 (52%), Gaps = 4/249 (1%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEA-GYTHIDTAYKYGIEDQ 317
++L++G ++P++ LG + + +G+ + E +I A++ GY IDTA Y E+
Sbjct: 4 IKLANGLHMPIIGLGVY---KAEGE------NCENTIIKAIDDYGYRMIDTAQVYFNEEF 54
Query: 318 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
VG A+ + +KRE IFITTK+W S + + ++ KSL+ L Y+DL L+H P
Sbjct: 55 VGNAIKQT---KIKREDIFITTKVWISNYGYNNTMYSISKSLKKLQTNYIDLVLLHQPFG 111
Query: 498 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE---KPSALQ 668
D+ W+ + K G+ K+IG+SNF + R++D L KP Q
Sbjct: 112 -----------DYYSAWKALEVLYKKGIVKAIGVSNF---EADRLVDFCLHVDVKPVINQ 157
Query: 669 IELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNK 848
IEL+ Q+ E + + + V ++ FG A +++ LV +A+KYNK
Sbjct: 158 IELHPLRQRIEDLHWNNKYGVAVESWASFG---------RATSEIMENPILVSLAEKYNK 208
Query: 849 TVPQVALRF 875
TVPQ+ LR+
Sbjct: 209 TVPQIILRW 217
>UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reductase;
n=1; Rhodococcus sp. RHA1|Rep: Probable
2,5-didehydrogluconate reductase - Rhodococcus sp.
(strain RHA1)
Length = 265
Score = 103 bits (247), Expect = 6e-21
Identities = 64/199 (32%), Positives = 106/199 (53%)
Frame = +3
Query: 162 NIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKK 341
+IP + LGTW P D +AV+ +EAGY IDTA Y ED VG AL +
Sbjct: 3 DIPPLGLGTWPLTGP---------DATRAVLSGIEAGYRLIDTATIYDNEDAVGVALAEC 53
Query: 342 FSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLL 521
G+ RE +F+TTKL S H + A+ +SL+NL L+ +DL+LIHWP+
Sbjct: 54 ---GVPREELFVTTKLRGSDHVSGDIRGAVERSLKNLGLDRLDLFLIHWPLPRHNR---- 106
Query: 522 DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPE 701
++ + M+ + GL + +G+SNF + ++R++ E P+ QI+++ +L +
Sbjct: 107 ----YVAAFEAMLACRDAGLVRHVGVSNFLETHLRRVVAETGESPAVNQIQMDPSLARLP 162
Query: 702 LFKFCRENDIVVMAYTPFG 758
+ + E + +++P G
Sbjct: 163 VRRADDELGVSTQSWSPLG 181
>UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1;
Griffithsia japonica|Rep: Mannose 6-phosphate reductase
- Griffithsia japonica (Red alga)
Length = 174
Score = 90.6 bits (215), Expect(2) = 6e-21
Identities = 50/116 (43%), Positives = 71/116 (61%), Gaps = 1/116 (0%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
T L SG +P+ GTW K V +TEQAV AL AGY HID A Y E
Sbjct: 5 TATLQSGAKMPLNGFGTW-----KASV----EETEQAVTAALRAGYRHIDCAAVYWNEAA 55
Query: 318 VGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 482
VG A++K S G+ KRE +FIT+K+WN+ H ++V+ + R+SL++ ++Y DL+L+
Sbjct: 56 VGTAISKAISGGVVKREDLFITSKVWNTCHATDKVVDSCRQSLKDHQVDYFDLFLV 111
Score = 33.5 bits (73), Expect(2) = 6e-21
Identities = 17/55 (30%), Positives = 29/55 (52%)
Frame = +3
Query: 558 IDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRE 722
+D L L + IG+SN++ + ++ KPS Q E ++ +P+L CRE
Sbjct: 103 VDYFDLFLVRDIGVSNYSVALLVDTLNYARIKPSVNQCEAHVYFARPQLRDVCRE 157
>UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase family;
n=5; Lactobacillus|Rep: Oxidoreductase aldo-keto
reductase family - Lactobacillus acidophilus
Length = 289
Score = 103 bits (246), Expect = 8e-21
Identities = 80/250 (32%), Positives = 120/250 (48%), Gaps = 2/250 (0%)
Frame = +3
Query: 132 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTE--QAVIYALEAGYTHIDTAYKYG 305
+P ++L+ G IP + G V Q++N E +AV A+ GY IDTA Y
Sbjct: 4 IPKIKLNDGNEIPQLGFG----------VFQISNHDEAVKAVESAISNGYRLIDTAEAYN 53
Query: 306 IEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 485
+ VG A+ + + R+ IF+TTKLW S E+ A+ + L+ L +Y+D+ L+H
Sbjct: 54 NQTAVGEAIK---NSDVNRDDIFLTTKLWVSNFTYEKASKAIDEDLKELGTDYIDMMLLH 110
Query: 486 WPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL 665
D WR + DA+K G TKSIG+SNF +Q+ + KP
Sbjct: 111 QAYG-----------DVAGAWRALEDAQKAGKTKSIGVSNFWPDQLMNLQLMSNVKPVVN 159
Query: 666 QIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYN 845
QIE+N Q+ K+ +++D+ V A+ PF K P L I +KY
Sbjct: 160 QIEVNPWFQREPEVKWNQKDDVAVEAWAPFAE---GKDGIFTNPV------LTEIGKKYG 210
Query: 846 KTVPQVALRF 875
K+ QV LR+
Sbjct: 211 KSNGQVILRW 220
>UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep:
Oxidoreductase - Xanthomonas campestris pv. campestris
(strain 8004)
Length = 267
Score = 103 bits (246), Expect = 8e-21
Identities = 72/195 (36%), Positives = 103/195 (52%), Gaps = 1/195 (0%)
Frame = +3
Query: 165 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF 344
+P LGT+ R K +VV +V AL GY IDTA Y E QVG+A+
Sbjct: 3 VPAFGLGTF---RLKDQVVI------DSVRNALALGYRAIDTAQIYDNEAQVGQAIA--- 50
Query: 345 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLD 524
G+ R+ +F+TTK+W R+ + P+L++SL L +YVDL LIHWP + D
Sbjct: 51 DAGVPRDQLFVTTKIWVDRFSRDTLQPSLQESLRKLGTDYVDLTLIHWP-------SPKD 103
Query: 525 NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID-SGLEKPSALQIELNLNLQQPE 701
V + + DAK GLT++IG+SNF ++ I+ G + + QIE++ LQ
Sbjct: 104 QVPMREYLEALADAKAQGLTRAIGVSNFTIALTRQAIEILGADAIATNQIEVHPYLQNRT 163
Query: 702 LFKFCRENDIVVMAY 746
L F RE I V +Y
Sbjct: 164 LIAFLREQGIHVTSY 178
>UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome.
precursor; n=1; Aspergillus niger|Rep: Contig An01c0460,
complete genome. precursor - Aspergillus niger
Length = 351
Score = 103 bits (246), Expect = 8e-21
Identities = 82/237 (34%), Positives = 115/237 (48%), Gaps = 20/237 (8%)
Frame = +3
Query: 168 PVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFS 347
P V LGT+ G V ++AV+ AL GY HIDTA YG E +VG A+ +
Sbjct: 47 PAVGLGTFQGDAGNRGV-------KEAVLQALRCGYRHIDTATAYGNEIEVGEAIKES-- 97
Query: 348 EGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEY---VDLY------LIHWPIAM 500
+ RE I +TTKL ++H V AL SLE L L Y + LY + H
Sbjct: 98 -RIPREEIIVTTKLAQTWHRVSDVERALDLSLERLQLNYGLSMHLYSASSYSVPHAYSPG 156
Query: 501 FENDTL--------LDNV---DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 647
+N+T+ +D+ D+ TW M G K IG+SNFN +++R++ S
Sbjct: 157 PDNNTIRHPNGKPIIDHELSRDYPSTWAAMESLVDKGKLKMIGVSNFNILKLERLLGSAR 216
Query: 648 EKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
P+ QIEL+ L Q EL +FC+ N I ++A+ P G + P A P ER
Sbjct: 217 IPPAVNQIELHPYLPQVELVRFCKANGIHLVAHQPLGGKPVAAVNPNADRPASKHER 273
>UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep:
Lin2848 protein - Listeria innocua
Length = 280
Score = 102 bits (245), Expect = 1e-20
Identities = 65/206 (31%), Positives = 104/206 (50%)
Frame = +3
Query: 258 ALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRK 437
A++ GY DTA Y E ++G S GLKR+ F+TTK+WN+ ++ + A K
Sbjct: 40 AVDVGYRLFDTASFYHNEKELGDFFA---SSGLKRDEFFVTTKMWNTEQGYDETLRAFEK 96
Query: 438 SLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQE 617
S + L L+ VDLYL+HWP + DT F +TWR + GL ++IG+SNF
Sbjct: 97 SQKKLQLDQVDLYLVHWP----KQDT------FFETWRAVEKLYDEGLVRAIGVSNFEAH 146
Query: 618 QIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPP 797
+ R+ S P Q+E + + L ++ E IV A++P G
Sbjct: 147 HLDRLRTSANVLPVVDQLETHPHFPNQLLHRYLEELHIVHQAWSPLGR-----------G 195
Query: 798 PRIDDERLVGIAQKYNKTVPQVALRF 875
+ ++ L+ +A+K+ K+ Q+ LR+
Sbjct: 196 GVLQEQILIDLAKKHGKSPAQIVLRW 221
>UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 302
Score = 102 bits (245), Expect = 1e-20
Identities = 74/214 (34%), Positives = 115/214 (53%), Gaps = 4/214 (1%)
Frame = +3
Query: 246 AVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKL--WNSYHEREQV 419
AV AL+ GYTHIDTA Y E VGRA+ + + RE IF+TTK+ + E E++
Sbjct: 38 AVKNALDCGYTHIDTAMAYENEAAVGRAIEQS---SVDREDIFLTTKIKGYPEMVEYERL 94
Query: 420 IPALRKSLENLNLEYVDLYLIHW--PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSI 593
I A + LE L EY+DL L+HW P+A E + + L+T ++D GL I
Sbjct: 95 IEAAKGCLERLGTEYLDLLLVHWWNPLADME-----ETFNALNT---LVDD---GLVGQI 143
Query: 594 GISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPS 773
G+SNF+ +++++ + + QIE + EL +FC++ND+ V AY+P
Sbjct: 144 GVSNFSIKELKQAMRLSDAPIATNQIEYHPYWGDEELVRFCQDNDVTVTAYSPL------ 197
Query: 774 KAQPXAPPPRIDDERLVGIAQKYNKTVPQVALRF 875
A ++D+ L I +Y K+ QV++R+
Sbjct: 198 -----AEGRAVEDDVLRSIGDRYGKSAAQVSIRW 226
>UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101765
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 288
Score = 102 bits (244), Expect = 1e-20
Identities = 70/211 (33%), Positives = 109/211 (51%), Gaps = 2/211 (0%)
Frame = +3
Query: 135 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 314
P++ L++ +P++ LGT+ R +G+ DT AV AL+AGY DTA Y E
Sbjct: 6 PSVLLNNDIQMPLLGLGTF---RLQGQ-----EDTYSAVDAALKAGYRAFDTAAVYRNEA 57
Query: 315 QVGRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 491
+G AL + GL RE +FIT+KL + + +KSLE L L Y+DLYLIHWP
Sbjct: 58 HLGHALRCLLPKHGLSREDVFITSKL-GPKDQGSKARNGCQKSLEQLGLGYIDLYLIHWP 116
Query: 492 IAM-FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 668
+ + +WR + + G ++IG+SN+ E +Q ++ S P+ LQ
Sbjct: 117 GTQGLPVGDKRNPENRAQSWRVLEEFYSEGKFRAIGVSNYTVEHMQELLKSCKVPPAVLQ 176
Query: 669 IELNLNLQQPELFKFCRENDIVVMAYTPFGS 761
+E + L Q +L C+ + AY+ G+
Sbjct: 177 VEFHPKLLQNDLRGLCKIRGVCFQAYSSLGT 207
>UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 305
Score = 102 bits (244), Expect = 1e-20
Identities = 69/226 (30%), Positives = 117/226 (51%), Gaps = 11/226 (4%)
Frame = +3
Query: 231 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEG-------LKRESIFITTKL 389
ND E + LE GY IDTA Y E+++G+ L + ++ +KRE +FIT+K
Sbjct: 38 NDIENIIKVGLENGYRRIDTASMYNNEERIGKVLNEMVTKNDGLDGKKIKREDLFITSKC 97
Query: 390 WNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP-IAMFENDTLLDNVDFLDTWRGMIDA 566
E + A SL+ L L+Y+D YLIHWP + + +++ TWR +
Sbjct: 98 SFMEQGYENALKAFESSLKKLQLDYLDCYLIHWPGVKGLDGSDSGNSIQRAQTWRALEKL 157
Query: 567 KKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIELN-LNLQQPELFKFCRENDIVV 737
+ +SIG+SN+ + ++ S L+ KP+ Q+E + LN Q+ +L +FC+ N I++
Sbjct: 158 YQDKKVRSIGVSNYTINHLTELLSSPNLQIKPAINQVEFHPLNFQK-DLLEFCKNNKIIL 216
Query: 738 MAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQVALRF 875
+Y GSL + +++E + A+K +T Q+ LR+
Sbjct: 217 ESY---GSLAGGRL--------LNNESVKEFAKKVGRTPSQLLLRY 251
>UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2;
Caenorhabditis|Rep: Probable oxidoreductase ZK1290.5 -
Caenorhabditis elegans
Length = 321
Score = 102 bits (244), Expect = 1e-20
Identities = 78/251 (31%), Positives = 128/251 (50%), Gaps = 2/251 (0%)
Frame = +3
Query: 129 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALE-AGYTHIDTAYKYG 305
++PT LS+ +P++ LGT AV+++++ GY IDTA +YG
Sbjct: 1 MIPTTVLSNNVEMPLIGLGT----------THSGGYYHDAVLHSIKKCGYRLIDTAKRYG 50
Query: 306 IEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 485
+E Q+G A+ K S + RE +F++TKLW ++V A + S E L +Y+D+Y+IH
Sbjct: 51 VEKQLGIAV-KNCS--VPREEMFLSTKLW-PVDCGDEVYNAFQTSCEKLQTDYLDMYMIH 106
Query: 486 WPIAMFENDTLLDNVDFLD-TWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 662
P D +++ + + TWR M + +SIG+SN++ E + +++ P A
Sbjct: 107 MPQLP---DWIVNQKETKEKTWRQMELLYEDEHVRSIGVSNYSIEDLDELLEFASILPHA 163
Query: 663 LQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKY 842
Q+EL+ Q +L +C E I+ M Y P A ++DE L IA KY
Sbjct: 164 NQVELHPWFHQADLKNYCDELGILTMGYCPL-----------AKGKYLEDETLCKIASKY 212
Query: 843 NKTVPQVALRF 875
K+ Q+ LR+
Sbjct: 213 QKSPAQICLRW 223
>UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n=1;
Rhizobium leguminosarum bv. viciae 3841|Rep: Putative
aldo-keto reductase/oxidase - Rhizobium leguminosarum
bv. viciae (strain 3841)
Length = 274
Score = 101 bits (243), Expect = 2e-20
Identities = 65/177 (36%), Positives = 97/177 (54%), Gaps = 3/177 (1%)
Frame = +3
Query: 231 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHER 410
++ Q VI+ALEAG HIDTA YG E V R + G+ R IFITTK+ +
Sbjct: 23 DEAHQGVIWALEAGCRHIDTAQGYGNEQDVARGIK---DAGVARNEIFITTKVKPDNYGP 79
Query: 411 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 590
V+P++R+SLE L ++ VDL L+HWP N L D+L + + D+ GL +
Sbjct: 80 GAVMPSVRESLEKLRVDQVDLLLLHWPSP--HNKYPL--ADYLGQFAEVFDS---GLARQ 132
Query: 591 IGISNFNQEQIQ---RIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTP 752
IG+SNF + I R++DS + Q+E ++ +Q + +C+ I V AY+P
Sbjct: 133 IGVSNFTKAMIDESIRLLDS--RTITTNQVECHVYMQNRPIIDYCQNLGIAVTAYSP 187
>UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3;
Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis
alexandrii HTCC2633
Length = 275
Score = 101 bits (243), Expect = 2e-20
Identities = 72/242 (29%), Positives = 111/242 (45%)
Frame = +3
Query: 150 SSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRA 329
++G +IP + GTW D + V AL+ GY HIDTA YG E VG
Sbjct: 7 ANGADIPKLGFGTWQLE---------DEDAARGVATALKTGYRHIDTAQIYGNEAAVGDG 57
Query: 330 LTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN 509
+ G+KRE F+TTK+W + ++++SL+ L +YVDL L+HWP+
Sbjct: 58 WKQS---GVKREDFFLTTKVWRDKFRDGDLQASVKESLDKLKTDYVDLLLLHWPV----- 109
Query: 510 DTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNL 689
V +T + M + K+ G + IG+SNF + + A Q+E + L
Sbjct: 110 ----PEVPIAETMKAMNEVKEAGQVRHIGVSNFTVDLLDEARAHSGAPLVANQVEYHPYL 165
Query: 690 QQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQVAL 869
Q + CR + + AY+P A DDE + IA+ +N + Q+ L
Sbjct: 166 DQNAVLTACRAAGMAMTAYSPI-----------AQGKVFDDEVITEIAKAHNVSPAQIVL 214
Query: 870 RF 875
R+
Sbjct: 215 RW 216
>UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis
vadensis ATCC BAA-548|Rep: Aldo/keto reductase -
Victivallis vadensis ATCC BAA-548
Length = 287
Score = 101 bits (242), Expect = 2e-20
Identities = 82/257 (31%), Positives = 126/257 (49%), Gaps = 9/257 (3%)
Frame = +3
Query: 132 VPTLQLSSGGNIPVVALGTWLGHRPKG-KVVQVTNDTEQ--AVIYALEAGYTHIDTAYKY 302
VP L +G IPV+ GTW R G ND A+ + G HIDTA Y
Sbjct: 4 VPWKSLKNGFAIPVLGQGTW---RMGGVDTPDTANDDADIAAIRRGIATGLCHIDTAEMY 60
Query: 303 G---IEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDL 473
E+ VG A+ +G++R F+T K+W ++ + V+ A SL+ L +Y+DL
Sbjct: 61 AGGHAEELVGIAMK---GQGIRRADYFLTDKVWKTHLRYDDVLRAAEASLKRLGTDYIDL 117
Query: 474 YLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEK 653
YLIH + +V +T R M K+ G+ + IG+SNF++E+++R +
Sbjct: 118 YLIH---------QVNPDVPEEETIRAMNRLKREGVIRHIGVSNFSEERLKRAQAASDAP 168
Query: 654 PSALQIELNLNLQQPE---LFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLV 824
A Q+ NL +++ E L +CR DI+V+A+ P L A P +V
Sbjct: 169 IVANQLHYNLRIREIEQCGLLDYCRSQDIMVIAWRPLRGL--DLALPL----------IV 216
Query: 825 GIAQKYNKTVPQVALRF 875
+A+KY KT Q+AL +
Sbjct: 217 TLAEKYGKTPSQIALNW 233
>UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5;
Bacteria|Rep: Morphine 6-dehydrogenase - Pseudomonas
putida
Length = 296
Score = 101 bits (242), Expect = 2e-20
Identities = 73/249 (29%), Positives = 118/249 (47%), Gaps = 2/249 (0%)
Frame = +3
Query: 135 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 314
P + L++G +P + LG + +T A+ A+ +GY IDTA Y E
Sbjct: 6 PLINLNNGVKMPALGLGVFAAS---------AEETASAIASAISSGYRLIDTARSYNNEA 56
Query: 315 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
QVG + + G+ R +F+TTKL+N + E+ + A +SL L L+YVDLYL+HWP
Sbjct: 57 QVGEGIR---NSGVDRAEMFVTTKLFNCDYGYERALRAFDESLGRLGLDYVDLYLLHWPT 113
Query: 495 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 674
+ N T + +W+ G ++IG+ NF ++Q+ +I + P+ QIE
Sbjct: 114 KDW-NAT-------IQSWKAAEKILGDGRARAIGVCNFLEDQLDELIAASDVVPAVNQIE 165
Query: 675 LNLNLQQPELFKFCRENDIVVMAYTPFGSLF--PSKAQPXAPPPRIDDERLVGIAQKYNK 848
L+ Q L R IV A++P G + D + IA+ + +
Sbjct: 166 LHPYFAQKPLLAKNRALGIVTEAWSPIGGAINDGDGDNHGGRKHPLTDPVITTIAEAHGR 225
Query: 849 TVPQVALRF 875
+ QV LR+
Sbjct: 226 SAAQVILRW 234
>UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1;
Helicobacter hepaticus|Rep: Putative uncharacterized
protein - Helicobacter hepaticus
Length = 270
Score = 101 bits (241), Expect = 3e-20
Identities = 80/246 (32%), Positives = 119/246 (48%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
TL L++G +P++ LGT+ GK Q +A+ A+E GY D+A Y E +
Sbjct: 3 TLTLNNGVKMPILGLGTY---SLTGKAGQ------KAMSEAIEVGYRLFDSAQMYNNEAE 53
Query: 318 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
+G A+ G+KRE FI TKL S E + ++ KSL+ L L+Y+D LIH P +
Sbjct: 54 LGAAINAAVKGGIKREEFFIQTKLLESSSE-DLAKKSIEKSLKTLGLDYIDSLLIHMPYS 112
Query: 498 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 677
+ +R M K G+ + IGISNF + + S P+ Q E
Sbjct: 113 QSK-----------AMYRAMESFYKQGILRVIGISNFGAKAYSEFVKSCEVIPAINQCET 161
Query: 678 NLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVP 857
+L LQQ L + + ++ +++PF K +++ L IAQKYNKT
Sbjct: 162 HLLLQQKPLREAMKSKKTLLQSWSPF---IAGKGS------ILENPTLKSIAQKYNKTPA 212
Query: 858 QVALRF 875
QV LRF
Sbjct: 213 QVVLRF 218
>UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides merdae ATCC 43184|Rep: Putative
uncharacterized protein - Parabacteroides merdae ATCC
43184
Length = 301
Score = 101 bits (241), Expect = 3e-20
Identities = 72/248 (29%), Positives = 121/248 (48%)
Frame = +3
Query: 132 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 311
VPT++L++G +P + +GT+L V ++ + V +A++ G+ IDTA YG E
Sbjct: 29 VPTVKLNNGMEMPQLGVGTFL----------VKDNAAERVCHAIKVGFRLIDTAQGYGNE 78
Query: 312 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 491
+VG + + G+ R +FITTK+ V +L KSL +L +Y+DL LIHWP
Sbjct: 79 KEVGEGICRS---GIDRRELFITTKVNTMEMRGGTVRQSLDKSLADLGTDYIDLVLIHWP 135
Query: 492 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 671
+ +TW+ + + G +SIG+SNFN + +++ +P QI
Sbjct: 136 V----------KGHIKETWQILEEYVDKGKIRSIGVSNFNPHHLDELLEYARIRPVVNQI 185
Query: 672 ELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKT 851
E+ + Q ++ + I V A+ P G +DD + IA ++ K+
Sbjct: 186 EIEPYMTQHDVVGYTFRKGIQVEAWGPLGQ---------GVTGVLDDPAIGEIAARHGKS 236
Query: 852 VPQVALRF 875
QV LR+
Sbjct: 237 AAQVILRW 244
>UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales
bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales
bacterium HTCC2654
Length = 278
Score = 101 bits (241), Expect = 3e-20
Identities = 72/247 (29%), Positives = 116/247 (46%)
Frame = +3
Query: 135 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 314
PT+ L++G +P + LGTW ++ +AV A+E GY IDTA Y E
Sbjct: 8 PTVTLANGVEMPQLGLGTW---------PMTDDEAAKAVATAIETGYRLIDTAENYKNET 58
Query: 315 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG+ + G+ R+ +F+TTK+ +H + A SLE L L+Y+DL+LIHWP
Sbjct: 59 GVGQGIR---DAGVARDEVFLTTKMNKQWHSVDGARRACEASLERLGLDYIDLFLIHWPN 115
Query: 495 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 674
D +++ + G+ GL ++IG SNF + + +G P QI+
Sbjct: 116 P--------DQGTYVEAFEGLTRLLDAGLVRAIGTSNFLPHHLNDLFAAGF-VPHVNQIQ 166
Query: 675 LNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTV 854
L+ +P++ IV +++P G A P + IA+ + KT
Sbjct: 167 LDPYHLRPDITAIHAAKGIVTESWSPIGRAGEMLADP----------AITRIAEAHGKTP 216
Query: 855 PQVALRF 875
Q+ LR+
Sbjct: 217 AQIVLRW 223
>UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3;
Pezizomycotina|Rep: Aldo-keto reductase, putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 283
Score = 100 bits (240), Expect = 4e-20
Identities = 79/256 (30%), Positives = 125/256 (48%), Gaps = 3/256 (1%)
Frame = +3
Query: 117 SADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAY 296
S+ L + L ++ + LG + P G+ VQ + + ALEAGY HIDTA
Sbjct: 2 SSKLTITDLLPLPNSDVKIPRLGFGVYRSPTGQCVQSS-------LRALEAGYRHIDTAQ 54
Query: 297 KYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLE--YVD 470
YG E +VG AL K G+ R +F+TTK+ + E L +S+E + YVD
Sbjct: 55 FYGNEKEVGEALRKC---GIPRSDVFVTTKILSPAGSPEATYQKLLESVEKIGGRDGYVD 111
Query: 471 LYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI-IDSGL 647
L+LIH + + + W+ + + G T+SIG+SNF + I+ + + +
Sbjct: 112 LFLIH--------SSSSGSAGRKELWQALERLLEEGKTRSIGVSNFGVKHIEEMKAYAKV 163
Query: 648 EKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVG 827
P QIEL+ QQ + +C+ N IVV AY+P + + +D LV
Sbjct: 164 WPPHVNQIELHPWCQQRVIEAYCKRNGIVVEAYSPLVRNY-----------KANDPTLVD 212
Query: 828 IAQKYNKTVPQVALRF 875
+A+KY +T Q+ +R+
Sbjct: 213 VAKKYERTTAQILIRY 228
>UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 282
Score = 100 bits (239), Expect = 6e-20
Identities = 77/245 (31%), Positives = 123/245 (50%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
+ L++G IP V LGT+L +D + AV YAL+ YT IDTA Y E V
Sbjct: 4 ITLNNGITIPQVGLGTYLLE---------PDDAQSAVTYALDNDYTLIDTANVYVNERAV 54
Query: 321 GRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 500
GR + + R+ IF+ TKLW S+ ER A+ ++LE L +Y+DL ++H P
Sbjct: 55 GRGMR---ASSKARDEIFLETKLWPSFFERAS---AVEETLERLGTDYIDLMILHQPAG- 107
Query: 501 FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELN 680
D + +R + A K G ++IG+SNF+ Q QRI+D P+ Q+E +
Sbjct: 108 ----------DTVAGYRILEKAHKEGKIRAIGLSNFDVAQTQRILDECEVVPTINQVECH 157
Query: 681 LNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQ 860
Q EL ++++I + A+ P G + + + G+A++++K+ Q
Sbjct: 158 PYFPQTELKALLKDHNITLQAWYPLGG--------RGNDSIMSEPIVQGLAEEHSKSPAQ 209
Query: 861 VALRF 875
V LR+
Sbjct: 210 VLLRW 214
>UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 286
Score = 100 bits (239), Expect = 6e-20
Identities = 77/245 (31%), Positives = 117/245 (47%), Gaps = 1/245 (0%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
+ +L +G +P + LGT+ G KV + V A++AGY HID A YG E+
Sbjct: 7 SFRLVNGSTLPAIGLGTFQGDDGNEKVKNI-------VKAAIQAGYRHIDGAAAYGNEEA 59
Query: 318 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
+G A+ + G+ R+ +L +HE + V AL SLE L LEYV + P
Sbjct: 60 IGDAIKES---GISRD------ELAQPWHEPKDVERALDLSLEALGLEYVPHAYLPGP-- 108
Query: 498 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 677
N + + +TW+ M G K+IG+SNFN + +RI++ +P+ Q+E
Sbjct: 109 --NNVDYERSRKYTETWQAMEKLVDSGKAKAIGLSNFNILKTKRILEIARIRPAVNQVEA 166
Query: 678 NLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAP-PPRIDDERLVGIAQKYNKTV 854
+ Q EL FC + I +MA+ P G P A P + D ++ IA + T
Sbjct: 167 HPYFPQHELLAFCEKEHIHLMAHQPLGGKPVGVVAPHADIPGPLFDTKIAQIAAQTGMTP 226
Query: 855 PQVAL 869
QV L
Sbjct: 227 AQVIL 231
>UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=15;
Proteobacteria|Rep: 2,5-diketo-D-gluconate reductase B -
Bradyrhizobium sp. (strain ORS278)
Length = 273
Score = 99 bits (238), Expect = 7e-20
Identities = 76/243 (31%), Positives = 121/243 (49%), Gaps = 1/243 (0%)
Frame = +3
Query: 150 SSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRA 329
+ G +P + LGT+ R +G V + AV AL GY HIDTA Y ED +G A
Sbjct: 6 TQGVRLPKLGLGTF---RMQGTVCR------DAVESALALGYRHIDTAEMYANEDAIGAA 56
Query: 330 LTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN 509
L + + RE + +TTK+W + + A SL+ L L++VDLYLIHWP
Sbjct: 57 LA---AAQIAREDLHVTTKVWPENLAPDAIRRAFDTSLKKLRLDFVDLYLIHWPATGMNL 113
Query: 510 DTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL-QIELNLN 686
++ ++ K+ G T++IG++NF +++ ++ ++ P A Q+E ++
Sbjct: 114 PAAMET---------LMALKQEGRTRAIGVANFTVALLKQAVED-IQAPVACNQVEYHVM 163
Query: 687 LQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQVA 866
L Q +L + + I ++AY P AQ A DE L GI +K+ QVA
Sbjct: 164 LDQSKLMAYMKSRSIPLVAYCPL-------AQGRA----AGDETLAGIGRKHGAGAAQVA 212
Query: 867 LRF 875
L++
Sbjct: 213 LKW 215
>UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 297
Score = 99 bits (238), Expect = 7e-20
Identities = 76/246 (30%), Positives = 128/246 (52%), Gaps = 4/246 (1%)
Frame = +3
Query: 144 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDT-EQAVIYALEAGYTHIDTAYKYGIEDQV 320
+L+SG NIP V GT+ +VT + A+ AL AGY DTA Y E ++
Sbjct: 14 KLNSGYNIPFVGFGTY----------KVTGENVPPAIDAALTAGYRMFDTAKYYLNEKEL 63
Query: 321 GRALTKKFSE-GLKRESIFITTKLW-NSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
G AL + GL R +F+T+K + S + RE + +SL++L +Y+D+YL+H+P
Sbjct: 64 GEALKILLPKHGLSRSDVFLTSKFFPESKNCREACRGFVEESLQSLQTDYIDMYLVHYPK 123
Query: 495 AMFENDTLLDNVDFLD-TWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 671
++ ++N ++ + + +AK G +SIG+SN+ ++ + P A Q+
Sbjct: 124 PNDSDNDDVNNAEYRKIAYEVLEEAKAAGKVRSIGVSNYEIVHLEELKTYAKVPPCANQL 183
Query: 672 ELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKT 851
E + + + L K+C+E +I A F SL + P I+D +V +A+K+N +
Sbjct: 184 EYHPHFARIPLQKYCKEKNIFFQA---FSSLARHE------PKLIEDPVVVELAKKHNTS 234
Query: 852 VPQVAL 869
VP V L
Sbjct: 235 VPLVLL 240
>UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Rep:
AkrI - Butyrivibrio fibrisolvens
Length = 172
Score = 99.5 bits (237), Expect = 1e-19
Identities = 57/167 (34%), Positives = 90/167 (53%), Gaps = 1/167 (0%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
++L++G IP+ GT+ ++ N+ +V AL+ GY HIDTA Y E V
Sbjct: 8 IKLNNGTAIPMFGYGTYK--------IKDQNEAYNSVRLALKNGYRHIDTAAFYENEKFV 59
Query: 321 GRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
A+ E KRE IF+T+K W + ++ + A K++ + ++Y+DLYL+HWP A
Sbjct: 60 ANAIKDFMEESQTKREDIFVTSKAWKTELGYDKTLAAFEKTMNEMQMDYLDLYLVHWP-A 118
Query: 498 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 638
+ D +N + TW+ M + K G K+IG+SNF + IID
Sbjct: 119 SYAFDDDWENTN-RQTWKAMTEIYKSGRVKAIGVSNFLTHHLDTIID 164
>UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1;
Schizosaccharomyces pombe|Rep: Xylose and arabinose
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 283
Score = 99.1 bits (236), Expect = 1e-19
Identities = 71/217 (32%), Positives = 113/217 (52%), Gaps = 2/217 (0%)
Frame = +3
Query: 231 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSE-GLKRESIFITTKLWNSYHE 407
N+ V AL++GY HIDTA YG ED G+A+ + +KR IF+T+KL N +
Sbjct: 32 NECYGLVTQALDSGYRHIDTAAVYGNEDICGKAIVDWCEKNNVKRTDIFLTSKLANC-SD 90
Query: 408 REQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTK 587
A+R SL +L Y+DL+LI P + +W+ M + G +
Sbjct: 91 YYSTRAAIRSSLHHLG-TYIDLFLIQSPAG--------GKKSRIASWKAMEEFVDSGDIR 141
Query: 588 SIGISNFNQEQIQRIIDSGLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSL 764
S+G+SN+ + +Q + S + P QIEL+ L Q ++ K+C+ +DI + AY+P
Sbjct: 142 SVGVSNYGVKHLQELYASNPKFYPCVNQIELHPFLSQDDIVKYCQSHDIAIEAYSPL--- 198
Query: 765 FPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQVALRF 875
R++DE+LV IA+K N +V Q+ +R+
Sbjct: 199 --------THGIRLNDEKLVPIAKKLNISVAQLLIRW 227
>UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9;
Dikarya|Rep: Aldo-keto reductase, putative - Aspergillus
clavatus
Length = 283
Score = 99.1 bits (236), Expect = 1e-19
Identities = 72/219 (32%), Positives = 111/219 (50%), Gaps = 3/219 (1%)
Frame = +3
Query: 228 TNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHE 407
T Q+ + AL+AGY +IDTA Y E +VG AL + G+ R +F+TTK+ +
Sbjct: 32 TRQCVQSCLTALQAGYRNIDTAQFYANEQEVGEALR---TSGIPRSDVFVTTKILSPAGS 88
Query: 408 REQVIPALRKSLENLNLE--YVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGL 581
E L +S+E + E YVDL+LIH + + + W+ + + G
Sbjct: 89 PEATYKKLLESVEKIGGENGYVDLFLIH--------SSSSGSAGRKELWQALEKLLEEGK 140
Query: 582 TKSIGISNFNQEQIQRI-IDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFG 758
TKSIG+SNF + I+ + + + P QIEL+ QQ + +C+ N IVV AY+P
Sbjct: 141 TKSIGVSNFGVKHIEEMKAYAKVWPPHVNQIELHPWCQQRVIDAYCKRNGIVVEAYSPLV 200
Query: 759 SLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQVALRF 875
+ + +D LV +A+KY KT QV +R+
Sbjct: 201 RNY-----------KANDPTLVDLAKKYGKTTAQVLIRY 228
>UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase
oxidoreductase protein; n=1; Spiroplasma citri|Rep:
Putative aldo/keto reductase oxidoreductase protein -
Spiroplasma citri
Length = 263
Score = 98.7 bits (235), Expect = 2e-19
Identities = 70/211 (33%), Positives = 110/211 (52%), Gaps = 1/211 (0%)
Frame = +3
Query: 240 EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF-SEGLKRESIFITTKLWNSYHEREQ 416
E+A+I AL+ GY IDTA Y E+ VGRA+ K S +RE I I TK+W E
Sbjct: 18 EEAIINALQNGYKIIDTAKVYQNEEIVGRAIKKYLNSNNQRREDIIIETKIWCDDVEAGN 77
Query: 417 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 596
A+ +SL+ LN+ Y+D+ LIH P F T+ V+ L K GL +G
Sbjct: 78 TTNAVLESLKRLNVTYLDIVLIHRPNLNFYK-TIKAYVELLQ-------CKAKGLINVVG 129
Query: 597 ISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSK 776
+SNF+++ I+ + + P+ QIE N Q+ + ++C+ +I+V +Y+P +
Sbjct: 130 VSNFDKDMIEILFEETGAYPNLNQIEFNPFNQRWDRVQYCQNKNILVQSYSPIAN----- 184
Query: 777 AQPXAPPPRIDDERLVGIAQKYNKTVPQVAL 869
++++ L A+KYN TV Q+ L
Sbjct: 185 --------TLENQTLATEAKKYNCTVAQLIL 207
>UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5;
Trypanosomatidae|Rep: Aldo-keto reductase-like protein -
Leishmania major strain Friedlin
Length = 372
Score = 98.3 bits (234), Expect = 2e-19
Identities = 67/217 (30%), Positives = 104/217 (47%), Gaps = 23/217 (10%)
Frame = +3
Query: 231 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF-SEGLKRESIFITTKLWNSYHE 407
++ AV +AL GY H+D A YG E VG AL + + +RE +F+T+KLW +
Sbjct: 43 SEATDAVAFALSCGYRHVDCAKAYGNEAAVGEALAQALRTRCTRREDLFVTSKLWPTDQH 102
Query: 408 REQVIPALRKSLENLNLEYVDLYLIHWPIAM-----FEND------------TLLDNVDF 536
+ V A R +L L L+Y+DLYLIHWP+ M + +D + +V
Sbjct: 103 PDHVEAACRATLAALQLDYLDLYLIHWPVCMRHTPHWTSDEDRYPRHRDGTPAIDTSVTL 162
Query: 537 LDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEK-----PSALQIELNLNLQQPE 701
LDTW M GL KSIG++N + ++ + E P Q+E + + +
Sbjct: 163 LDTWTAMNRLVDRGLVKSIGLANCTTAHVNDLVKAVAEAKLAHLPVLNQVEHHPGIVDGD 222
Query: 702 LFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDD 812
L +D+++ AY P G P+ + P +DD
Sbjct: 223 LIGCLGSHDMLMAAYCPLG--MPTCSTPPGFQSLLDD 257
>UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22;
Pezizomycotina|Rep: Aldehyde reductase, putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 295
Score = 98.3 bits (234), Expect = 2e-19
Identities = 69/217 (31%), Positives = 118/217 (54%), Gaps = 4/217 (1%)
Frame = +3
Query: 237 TEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQ 416
TE+A + ALE GY HID+A Y E + A+ K G+ R IF TTK+ S E+
Sbjct: 46 TEKATLKALETGYRHIDSAKYYANEKECAVAMKKS---GIDRSKIFFTTKVPASSMSYEK 102
Query: 417 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 596
A+ +S+ +L Y+DL L+H P E L WR +++A+K G +SIG
Sbjct: 103 AKEAIEQSVAATDLGYIDLILLHAPYGGKEGR--------LGAWRALVEAQKAGHVRSIG 154
Query: 597 ISNF---NQEQIQRIIDSGL-EKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSL 764
+SN+ + E+++ I+SG+ + S Q E++ + ++ + ++ ++V+ AY+P
Sbjct: 155 VSNYGIHHLEELEEYINSGVGGEISVGQYEIHPWCAREDIVAWLKKRNVVIEAYSPL--- 211
Query: 765 FPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQVALRF 875
+AQ R+D+ L +A+K+NKT Q+ +R+
Sbjct: 212 --VQAQ------RLDEPVLQNLAKKHNKTGAQILIRW 240
>UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1;
Phytophthora infestans|Rep: Aldo-keto reductase,
putative - Phytophthora infestans (Potato late blight
fungus)
Length = 255
Score = 97.9 bits (233), Expect = 3e-19
Identities = 63/194 (32%), Positives = 100/194 (51%)
Frame = +3
Query: 132 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 311
VPT L SG IP++ LG + + +T A++ +L+ GY HIDTA YG E
Sbjct: 5 VPTKILPSGARIPMIGLGVYQS--------EPGPETYNAILTSLKLGYRHIDTAEIYGNE 56
Query: 312 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 491
+ VGRA+ G+ RE IF+TTKL+ + + + A + S + L + Y+ LYL+H P
Sbjct: 57 EDVGRAVR---DSGIPREEIFVTTKLFTTNWGYSKALAAGKASNDRLGIVYIYLYLLHAP 113
Query: 492 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 671
E DTWR + D ++ + IG+SNFN+ + + + KP+ Q+
Sbjct: 114 GPPKER---------ADTWRAVEDLREQETLRDIGVSNFNETLLATLRKTAHIKPAVNQV 164
Query: 672 ELNLNLQQPELFKF 713
EL+ + + L +
Sbjct: 165 ELHPWMMRQSLVNY 178
>UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;
Lactobacillus|Rep: Aldo/keto reductase family enzyme -
Lactobacillus casei (strain ATCC 334)
Length = 281
Score = 97.5 bits (232), Expect = 4e-19
Identities = 61/205 (29%), Positives = 109/205 (53%), Gaps = 3/205 (1%)
Frame = +3
Query: 156 GGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALT 335
G N+P++ +GTW + +G Q + A+ Y L G T IDTA YG + +L
Sbjct: 8 GVNVPIMGMGTW--YLGEGNAAQSEQEAA-ALKYGLNHGLTVIDTAEMYG--NGAAESLI 62
Query: 336 KKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDT 515
F R +I++ +K + S+ ++ Q++ AL+ SL+ L +Y+DLYL+HW
Sbjct: 63 GSFLGDYDRANIYLISKFYPSHADKRQMLTALKNSLKRLQTDYLDLYLLHW--------- 113
Query: 516 LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI-IDSGLEKPSALQIELNLNLQ 692
+ +T G+ D +K GL K G+SNF+ + + ++ ++ G ++ +A ++ NL +
Sbjct: 114 -RGSTPLAETLEGLQDLQKEGLIKQYGVSNFDVDDMDQLTLEPGGDQIAANEVLYNLQSR 172
Query: 693 QPE--LFKFCRENDIVVMAYTPFGS 761
E L ++ +I + Y+PFGS
Sbjct: 173 SIEYDLLPQQKQANITTIGYSPFGS 197
>UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1;
Schizosaccharomyces pombe|Rep: Xylose and arabinose
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 275
Score = 97.5 bits (232), Expect = 4e-19
Identities = 72/247 (29%), Positives = 121/247 (48%), Gaps = 2/247 (0%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
++L++G P A G+++ +R K +V AL+ GY HID+A Y E
Sbjct: 6 VKLNNGLKCPQFAYGSYMVNRTK---------CFDSVYAALQCGYRHIDSAQMYHNEADC 56
Query: 321 GRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
GRA+ K E G KRE I+ T+KL N + + ++ S++ L Y+DL+L+H P
Sbjct: 57 GRAILKFMEETGTKREDIWFTSKL-NDLSGYKSTLSSIDASVKACGLGYIDLFLLHSPYG 115
Query: 498 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE-KPSALQIE 674
D +++W+ + + G ++IG+SNF IQ ++DS + P QIE
Sbjct: 116 -----------DRIESWKALEKGVEEGKLRAIGVSNFGPHHIQELLDSHPKIIPCVNQIE 164
Query: 675 LNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTV 854
L+ Q ++ +C I + AY P + +++L+ IA KYNK+
Sbjct: 165 LHPFCSQQKVVDYCESKGIQLAAYAPL-----------VHGEKFGNKQLLAIASKYNKSE 213
Query: 855 PQVALRF 875
Q+ +R+
Sbjct: 214 AQIMIRY 220
>UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2;
Halobacteriaceae|Rep: Alcohol dehydrogenase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 667
Score = 97.5 bits (232), Expect = 4e-19
Identities = 63/237 (26%), Positives = 114/237 (48%), Gaps = 25/237 (10%)
Frame = +3
Query: 234 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHERE 413
D ++ AL+AGY +D+A YG E ++GR L + +R +FI K+W + H R+
Sbjct: 395 DRADSIAAALDAGYRLLDSAELYGNEHRIGRILAAPGAPDRRR--VFILGKVWRTNHRRK 452
Query: 414 QVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTL------------------------- 518
++ A R SL+ L ++ D Y +HWP A+ +L
Sbjct: 453 HMLTACRSSLDELGIDAFDCYALHWPEALAHRGSLTRLAEKSVARQEALTFPKNDRGDIE 512
Query: 519 LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQP 698
D+V W + + G T+++G+ N +Q Q++ +I++G +P+ +Q+E + Q
Sbjct: 513 TDSVSLQRAWENLEALHERGWTRTLGLCNVSQTQLETVIETGTVRPALVQVERHPYQPQT 572
Query: 699 ELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQVAL 869
+L ++C E I V+A++P + P +D+ L IA++Y + V L
Sbjct: 573 DLIEYCHERGIRVVAHSPLSA-----------PGLLDEPVLAAIAEEYGLSPAGVVL 618
>UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr1 scaffold_5, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 247
Score = 96.7 bits (230), Expect = 7e-19
Identities = 56/156 (35%), Positives = 88/156 (56%), Gaps = 11/156 (7%)
Frame = +3
Query: 246 AVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL--KRESIFITTKLWNSYHEREQV 419
+++ A+E GY H D Y E +G A+ K GL R+ +FIT+KLW S ++V
Sbjct: 37 SILTAIELGYRHFDCVAAYLSEKPLGEAIKKAVKLGLIKSRDELFITSKLWCSDAHHDRV 96
Query: 420 IPALRKSLE---------NLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKK 572
+PAL+ +L+ NL L+Y+DLYLIHW +D L +D W+ M D +K
Sbjct: 97 LPALQNTLKISSILSFSKNLQLDYLDLYLIHW------SDGHLP-IDLGSVWKAMEDFQK 149
Query: 573 LGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELN 680
L LTK+IG+SNF+ +++ ++ + P+ Q+ N
Sbjct: 150 LSLTKAIGVSNFSCNKLEELLQTASILPAVNQVSEN 185
>UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep:
Aldo / keto reductase - Thermoplasma volcanium
Length = 288
Score = 96.7 bits (230), Expect = 7e-19
Identities = 63/187 (33%), Positives = 104/187 (55%), Gaps = 6/187 (3%)
Frame = +3
Query: 243 QAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVI 422
QA+ A++AG T IDTA YG ED V +A+ EG RE +FI TK+W ++ ++VI
Sbjct: 50 QAIRTAIDAGVTLIDTAEIYGSEDLVAKAI-----EGHNREELFIATKVWINHLRYDKVI 104
Query: 423 PALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGIS 602
A + SL LN +YVDLY IH+P + +T++ M GL K IG+S
Sbjct: 105 KACKASLSRLNTKYVDLYQIHFP---------SPTANLQETFKAMEKLVDDGLVKFIGVS 155
Query: 603 NFNQEQIQRIIDSGLEKPSALQIELNLNLQ----QPELFKFCRENDIVVMAYTPF--GSL 764
NF++ ++++ ++ ++K + +++ +L+ + ++ KFC N + V+A+ P GSL
Sbjct: 156 NFSRGKLEKSMEY-VKKYEIVSNQIHYSLKKRDAEEDIVKFCENNGMAVLAWYPLEHGSL 214
Query: 765 FPSKAQP 785
P
Sbjct: 215 VRESDYP 221
>UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase
family; n=2; Sulfolobaceae|Rep: Oxidoreductase,
aldo/keto reductase family - Sulfolobus solfataricus
Length = 265
Score = 96.3 bits (229), Expect = 9e-19
Identities = 70/213 (32%), Positives = 114/213 (53%), Gaps = 6/213 (2%)
Frame = +3
Query: 255 YALEAGYTHIDTAYKYG---IEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIP 425
Y + G IDTA YG E+ VG+A+ E R+ IFI TK+W+++ + + +I
Sbjct: 39 YVISKGINVIDTAEMYGGGHSEELVGKAI-----ENFDRDKIFIITKVWSNHLKYDDLIR 93
Query: 426 ALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISN 605
+ + SL+ LN +Y+DLYLIHWP + +V ++ R M + G+ IG+SN
Sbjct: 94 SAKNSLKRLNAKYIDLYLIHWPNS---------SVPLEESLRAMEELVDQGIVNCIGVSN 144
Query: 606 FNQEQIQRIID-SGLEKPSALQIELNLNLQQPE--LFKFCRENDIVVMAYTPFGSLFPSK 776
F+ + ++ + + + +A +IE N+ + E + FC N+I V+AY+P
Sbjct: 145 FDIKLLEETMSITKKYEITANEIEYNVENKSAEKDVIPFCERNNIKVIAYSPL------- 197
Query: 777 AQPXAPPPRIDDERLVGIAQKYNKTVPQVALRF 875
A+ A +I +E I +KYNKT QVAL +
Sbjct: 198 ARGNAKNNKILEE----IGRKYNKTSVQVALNY 226
>UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6;
Halobacteriaceae|Rep: Aldehyde reductase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 279
Score = 96.3 bits (229), Expect = 9e-19
Identities = 66/197 (33%), Positives = 100/197 (50%), Gaps = 1/197 (0%)
Frame = +3
Query: 165 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF 344
+P++ LGTW + ++V ALEAGY HIDTA Y E VG +
Sbjct: 17 MPMLGLGTWQN--------EDAEQCAESVRTALEAGYRHIDTAQAYDNESAVGDGIA--- 65
Query: 345 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLD 524
+ + R+ IF+ TK+W S + VI +SL+ L ++ VDL +HW +E + L
Sbjct: 66 AADVDRDDIFLATKVWISNLSHDDVIETTEESLDKLGVDSVDLLYVHWAAGEYEPEETLP 125
Query: 525 NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKP-SALQIELNLNLQQPE 701
D L RG+ID ++G+SNF ++ +D L+ P A Q+E + LQQ E
Sbjct: 126 AFDEL-VDRGLID--------NVGVSNFEPHHVETAMDV-LDAPVFANQVETHPFLQQSE 175
Query: 702 LFKFCRENDIVVMAYTP 752
L + E D ++AY+P
Sbjct: 176 LREHAAEQDYELVAYSP 192
>UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep:
Tlr1054 protein - Synechococcus elongatus
(Thermosynechococcus elongatus)
Length = 320
Score = 95.5 bits (227), Expect = 2e-18
Identities = 61/196 (31%), Positives = 101/196 (51%)
Frame = +3
Query: 165 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF 344
I + LGTW + ++ ++ + + A+EAG T IDTA YG E R +
Sbjct: 13 ITPLILGTWQAGKRWWVGIE-DEESIRTIRAAVEAGMTTIDTAEVYG-EGHSERIVAA-- 68
Query: 345 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLD 524
+ G R+ TK++ ++ + VI A +SL NLN +Y+DLY IHWP F ++
Sbjct: 69 AVGDLRDRCVYATKVFANHLRYKDVIAACERSLRNLNTDYIDLYQIHWPAGSFGSEI--- 125
Query: 525 NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPEL 704
V +T + M++ + G ++IG+SNF++ Q+ + G + L + EL
Sbjct: 126 -VPIEETMQAMVELQAAGKIRAIGVSNFSRAQLAEAMQYGRIESVQPPYSLFWRWAEAEL 184
Query: 705 FKFCRENDIVVMAYTP 752
FC E++I V+AY+P
Sbjct: 185 IPFCIEHEITVLAYSP 200
>UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Lactobacillus acidophilus
Length = 278
Score = 95.1 bits (226), Expect = 2e-18
Identities = 69/212 (32%), Positives = 108/212 (50%)
Frame = +3
Query: 240 EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQV 419
+Q V LE GY +DTA YG E VG A+ K S + RE IFIT+K+W + +
Sbjct: 30 QQVVEDGLEVGYRLVDTAQIYGNEQAVGDAI--KHSN-VPREDIFITSKIWVDDYGYDNT 86
Query: 420 IPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGI 599
+ A S++ L L+Y+DLYLIH P D+ TWR + + G ++IG+
Sbjct: 87 LKAFDDSMKKLQLDYIDLYLIHKPYN-----------DYYGTWRALERLYQEGRIRAIGV 135
Query: 600 SNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKA 779
S+F E++ +I KP+ QIE N+ Q+ + ++ + + A+ PF A
Sbjct: 136 SSFWNERLADLITFNDVKPAVNQIETNVWNQEWKSQQYMEKEGVQPEAWAPFA----EGA 191
Query: 780 QPXAPPPRIDDERLVGIAQKYNKTVPQVALRF 875
P +++ IA+K++KT QV LR+
Sbjct: 192 NHIFTNPLLEE-----IAEKHHKTTAQVMLRW 218
>UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=3; Archaea|Rep: 2,5-diketo-D-gluconic acid reductase A
- Sulfolobus acidocaldarius
Length = 267
Score = 95.1 bits (226), Expect = 2e-18
Identities = 71/217 (32%), Positives = 113/217 (52%), Gaps = 6/217 (2%)
Frame = +3
Query: 243 QAVIYALEAGYTHIDTAYKYG---IEDQVGRALTKKFSEGLKRESIFITTKLWNSYHERE 413
+A+ Y + G IDTA YG E+ VG+A+ RES+FITTK+W ++ + +
Sbjct: 35 EAIKYTINKGINLIDTAEMYGGGHTEEIVGKAVAD-----FDRESLFITTKVWPNHLKYD 89
Query: 414 QVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSI 593
I + SL+ LN +Y+DLYLIHWP D ++ + + +ID +G+ + I
Sbjct: 90 DTIKSALASLKRLNTKYIDLYLIHWP----NPDVKVE--ETISAMEKLID---MGVVRCI 140
Query: 594 GISNFNQEQIQRIIDSGLE-KPSALQIELNLNLQQPE--LFKFCRENDIVVMAYTPFGSL 764
G+SNF+ + + + I S + + A QI+ ++ PE + F +N + ++AY+P G
Sbjct: 141 GVSNFDVKLLDQAIHSTKKYEIVANQIQYSIYRLTPERDVIPFAEKNKVTIIAYSPLGQG 200
Query: 765 FPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQVALRF 875
S + RL IA KY KT QVAL +
Sbjct: 201 SIS-----------SESRLKDIALKYGKTQAQVALAY 226
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 944,238,801
Number of Sequences: 1657284
Number of extensions: 20563839
Number of successful extensions: 65292
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 61326
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 64232
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 79112361923
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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