Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP15_F_G19
(881 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 178 2e-44
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 176 8e-44
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 176 8e-44
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 176 8e-44
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 176 8e-44
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 176 8e-44
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 176 8e-44
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 176 8e-44
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 176 8e-44
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 176 8e-44
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 176 8e-44
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 176 1e-43
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 175 1e-43
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 173 7e-43
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 173 7e-43
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 173 7e-43
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 173 7e-43
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 173 7e-43
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 173 7e-43
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 173 7e-43
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 173 7e-43
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 173 7e-43
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 173 7e-43
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 173 9e-43
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 173 9e-43
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 173 9e-43
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 173 9e-43
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 173 9e-43
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 173 9e-43
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 173 9e-43
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 173 9e-43
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 173 9e-43
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 171 2e-42
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 171 2e-42
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 171 2e-42
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 171 2e-42
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 171 2e-42
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 171 2e-42
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 171 3e-42
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 171 3e-42
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 171 4e-42
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 170 7e-42
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 170 7e-42
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 170 7e-42
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 170 7e-42
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 170 7e-42
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 170 7e-42
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 170 7e-42
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 169 9e-42
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 169 1e-41
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 169 2e-41
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 169 2e-41
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 169 2e-41
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 169 2e-41
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 169 2e-41
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 168 2e-41
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 168 3e-41
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 168 3e-41
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 168 3e-41
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 168 3e-41
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 168 3e-41
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 167 4e-41
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 167 6e-41
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 167 6e-41
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 167 6e-41
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 166 8e-41
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 165 2e-40
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 165 2e-40
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 165 2e-40
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 165 2e-40
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 165 2e-40
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 165 2e-40
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 165 2e-40
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 165 2e-40
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 165 2e-40
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 164 3e-40
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 95 1e-36
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 95 1e-36
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 95 1e-36
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 141 3e-33
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 95 2e-29
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 95 2e-29
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 121 3e-27
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 121 3e-27
AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 108 2e-23
BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 97 6e-20
BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 97 6e-20
AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 97 6e-20
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 95 2e-19
AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto red... 90 9e-18
AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens ... 74 8e-13
U33429-1|AAC50955.1| 367|Homo sapiens K+ channel beta 2 subunit... 49 2e-05
CR542287-1|CAG47082.1| 353|Homo sapiens KCNAB2 protein. 49 2e-05
BC130413-1|AAI30414.1| 367|Homo sapiens potassium voltage-gated... 49 2e-05
BC126424-1|AAI26425.1| 367|Homo sapiens potassium voltage-gated... 49 2e-05
BC110351-1|AAI10352.1| 395|Homo sapiens KCNAB2 protein protein. 49 2e-05
AL035406-6|CAI19886.1| 253|Homo sapiens potassium voltage-gated... 49 2e-05
AL035406-5|CAI19887.1| 254|Homo sapiens potassium voltage-gated... 49 2e-05
AL035406-4|CAC08512.1| 367|Homo sapiens potassium voltage-gated... 49 2e-05
AL035406-3|CAI19885.1| 353|Homo sapiens potassium voltage-gated... 49 2e-05
AK131252-1|BAD18431.1| 415|Homo sapiens protein ( Homo sapiens ... 49 2e-05
AF044253-1|AAB99859.1| 353|Homo sapiens potassium channel beta ... 49 2e-05
AF029749-1|AAB84170.1| 367|Homo sapiens potassium channel beta ... 49 2e-05
CR542264-1|CAG47060.1| 353|Homo sapiens KCNAB2 protein. 47 1e-04
AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthas... 46 2e-04
BC099634-1|AAH99634.1| 404|Homo sapiens potassium voltage-gated... 46 2e-04
BC096234-1|AAH96234.1| 404|Homo sapiens potassium voltage-gated... 46 2e-04
BC096232-1|AAH96232.1| 404|Homo sapiens potassium voltage-gated... 46 2e-04
AF016411-1|AAB92499.1| 404|Homo sapiens KCNA3.1B protein. 44 6e-04
AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto red... 38 0.048
AF026947-1|AAC52104.1| 330|Homo sapiens aflatoxin aldehyde redu... 36 0.26
Y16675-1|CAA76347.1| 330|Homo sapiens aflatoxin B1-aldehyde red... 35 0.34
BT007347-1|AAP36011.1| 330|Homo sapiens aldo-keto reductase fam... 35 0.34
BC013996-1|AAH13996.1| 330|Homo sapiens AKR7A2 protein protein. 35 0.34
BC012171-1|AAH12171.1| 330|Homo sapiens AKR7A2 protein protein. 35 0.34
BC011586-1|AAH11586.1| 330|Homo sapiens AKR7A2 protein protein. 35 0.34
BC010852-1|AAH10852.1| 330|Homo sapiens AKR7A2 protein protein. 35 0.34
BC007352-1|AAH07352.2| 358|Homo sapiens AKR7A2 protein protein. 35 0.34
BC004111-1|AAH04111.3| 330|Homo sapiens AKR7A2 protein protein. 35 0.34
AL035413-8|CAB72321.1| 330|Homo sapiens aldo-keto reductase fam... 35 0.34
BC075018-1|AAH75018.1| 599|Homo sapiens DEAQ box polypeptide 1 ... 32 3.2
AK074337-1|BAB85056.1| 599|Homo sapiens protein ( Homo sapiens ... 32 3.2
M64590-1|AAA36463.1| 1020|Homo sapiens glycine decarboxylase pro... 31 5.5
M63635-1|AAA36478.1| 1020|Homo sapiens glycine decarboxylase pro... 31 5.5
D90239-1|BAA14286.1| 1020|Homo sapiens glycine decarboxylase pre... 31 5.5
BC111995-1|AAI11996.1| 1020|Homo sapiens glycine dehydrogenase (... 31 5.5
BC111993-1|AAI11994.1| 1020|Homo sapiens glycine dehydrogenase (... 31 5.5
AL353718-2|CAH74116.1| 1036|Homo sapiens glycine dehydrogenase (... 31 5.5
AL162411-3|CAH69992.1| 1036|Homo sapiens glycine dehydrogenase (... 31 5.5
AF246134-1|AAK28443.2| 331|Homo sapiens glycine decarboxylase P... 31 5.5
BC042420-1|AAH42420.2| 331|Homo sapiens aldo-keto reductase fam... 31 7.3
BC031562-1|AAH31562.1| 331|Homo sapiens aldo-keto reductase fam... 31 7.3
BC029488-1|AAH29488.1| 294|Homo sapiens sperm acrosome associat... 31 7.3
AL136096-1|CAI19915.1| 294|Homo sapiens sperm acrosome associat... 31 7.3
AJ271799-1|CAC81076.1| 331|Homo sapiens aflatoxin B1 aldehyde r... 31 7.3
AF203447-1|AAG31422.1| 294|Homo sapiens sperm acrosome membrane... 31 7.3
AF040639-1|AAD02195.1| 331|Homo sapiens aflatoxin B1-aldehyde r... 31 7.3
BC025709-1|AAH25709.1| 331|Homo sapiens aldo-keto reductase fam... 30 9.7
AL035413-11|CAI22232.1| 331|Homo sapiens aldo-keto reductase fa... 30 9.7
AK092420-1|BAC03884.1| 357|Homo sapiens protein ( Homo sapiens ... 30 9.7
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 178 bits (434), Expect = 2e-44
Identities = 107/258 (41%), Positives = 154/258 (59%), Gaps = 13/258 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 321 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
G A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWPI
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPIG 115
Query: 498 ------MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 644
F D + + + LDTW M + GL K+IGISNFN Q++ I++ G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175
Query: 645 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERL 821
L+ KP+ QIE + L Q +L ++C+ IVV AY+P GS A+P P ++D R+
Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKP-EDPSLLEDPRI 234
Query: 822 VGIAQKYNKTVPQVALRF 875
IA K+NKT QV +RF
Sbjct: 235 KAIAAKHNKTTAQVLIRF 252
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 176 bits (429), Expect = 8e-44
Identities = 106/258 (41%), Positives = 153/258 (59%), Gaps = 13/258 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 321 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
G A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 498 ------MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 644
F D + + + LDTW M + GL K+IGISNFN Q++ I++ G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175
Query: 645 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERL 821
L+ KP+ QIE + L Q +L ++C+ IVV AY+P GS A+P P ++D R+
Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKP-EDPSLLEDPRI 234
Query: 822 VGIAQKYNKTVPQVALRF 875
IA K+NKT QV +RF
Sbjct: 235 KAIAAKHNKTTAQVLIRF 252
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 176 bits (429), Expect = 8e-44
Identities = 106/258 (41%), Positives = 153/258 (59%), Gaps = 13/258 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 321 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
G A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 498 ------MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 644
F D + + + LDTW M + GL K+IGISNFN Q++ I++ G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175
Query: 645 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERL 821
L+ KP+ QIE + L Q +L ++C+ IVV AY+P GS A+P P ++D R+
Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKP-EDPSLLEDPRI 234
Query: 822 VGIAQKYNKTVPQVALRF 875
IA K+NKT QV +RF
Sbjct: 235 KAIAAKHNKTTAQVLIRF 252
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 176 bits (429), Expect = 8e-44
Identities = 106/258 (41%), Positives = 153/258 (59%), Gaps = 13/258 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 321 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
G A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 498 ------MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 644
F D + + + LDTW M + GL K+IGISNFN Q++ I++ G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175
Query: 645 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERL 821
L+ KP+ QIE + L Q +L ++C+ IVV AY+P GS A+P P ++D R+
Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKP-EDPSLLEDPRI 234
Query: 822 VGIAQKYNKTVPQVALRF 875
IA K+NKT QV +RF
Sbjct: 235 KAIAAKHNKTTAQVLIRF 252
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 176 bits (429), Expect = 8e-44
Identities = 106/258 (41%), Positives = 153/258 (59%), Gaps = 13/258 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 321 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
G A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 498 ------MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 644
F D + + + LDTW M + GL K+IGISNFN Q++ I++ G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175
Query: 645 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERL 821
L+ KP+ QIE + L Q +L ++C+ IVV AY+P GS A+P P ++D R+
Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKP-EDPSLLEDPRI 234
Query: 822 VGIAQKYNKTVPQVALRF 875
IA K+NKT QV +RF
Sbjct: 235 KAIAAKHNKTTAQVLIRF 252
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 176 bits (429), Expect = 8e-44
Identities = 106/258 (41%), Positives = 153/258 (59%), Gaps = 13/258 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 321 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
G A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 498 ------MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 644
F D + + + LDTW M + GL K+IGISNFN Q++ I++ G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175
Query: 645 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERL 821
L+ KP+ QIE + L Q +L ++C+ IVV AY+P GS A+P P ++D R+
Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKP-EDPSLLEDPRI 234
Query: 822 VGIAQKYNKTVPQVALRF 875
IA K+NKT QV +RF
Sbjct: 235 KAIAAKHNKTTAQVLIRF 252
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 176 bits (429), Expect = 8e-44
Identities = 106/258 (41%), Positives = 153/258 (59%), Gaps = 13/258 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 321 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
G A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 498 ------MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 644
F D + + + LDTW M + GL K+IGISNFN Q++ I++ G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175
Query: 645 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERL 821
L+ KP+ QIE + L Q +L ++C+ IVV AY+P GS A+P P ++D R+
Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKP-EDPSLLEDPRI 234
Query: 822 VGIAQKYNKTVPQVALRF 875
IA K+NKT QV +RF
Sbjct: 235 KAIAAKHNKTTAQVLIRF 252
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 176 bits (429), Expect = 8e-44
Identities = 106/258 (41%), Positives = 153/258 (59%), Gaps = 13/258 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 321 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
G A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 498 ------MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 644
F D + + + LDTW M + GL K+IGISNFN Q++ I++ G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175
Query: 645 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERL 821
L+ KP+ QIE + L Q +L ++C+ IVV AY+P GS A+P P ++D R+
Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKP-EDPSLLEDPRI 234
Query: 822 VGIAQKYNKTVPQVALRF 875
IA K+NKT QV +RF
Sbjct: 235 KAIAAKHNKTTAQVLIRF 252
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 176 bits (429), Expect = 8e-44
Identities = 106/258 (41%), Positives = 153/258 (59%), Gaps = 13/258 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 321 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
G A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 498 ------MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 644
F D + + + LDTW M + GL K+IGISNFN Q++ I++ G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175
Query: 645 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERL 821
L+ KP+ QIE + L Q +L ++C+ IVV AY+P GS A+P P ++D R+
Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKP-EDPSLLEDPRI 234
Query: 822 VGIAQKYNKTVPQVALRF 875
IA K+NKT QV +RF
Sbjct: 235 KAIAAKHNKTTAQVLIRF 252
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 176 bits (429), Expect = 8e-44
Identities = 106/258 (41%), Positives = 153/258 (59%), Gaps = 13/258 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 321 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
G A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 498 ------MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 644
F D + + + LDTW M + GL K+IGISNFN Q++ I++ G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175
Query: 645 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERL 821
L+ KP+ QIE + L Q +L ++C+ IVV AY+P GS A+P P ++D R+
Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKP-EDPSLLEDPRI 234
Query: 822 VGIAQKYNKTVPQVALRF 875
IA K+NKT QV +RF
Sbjct: 235 KAIAAKHNKTTAQVLIRF 252
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 176 bits (429), Expect = 8e-44
Identities = 106/258 (41%), Positives = 153/258 (59%), Gaps = 13/258 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 321 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
G A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 498 ------MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 644
F D + + + LDTW M + GL K+IGISNFN Q++ I++ G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175
Query: 645 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERL 821
L+ KP+ QIE + L Q +L ++C+ IVV AY+P GS A+P P ++D R+
Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKP-EDPSLLEDPRI 234
Query: 822 VGIAQKYNKTVPQVALRF 875
IA K+NKT QV +RF
Sbjct: 235 KAIAAKHNKTTAQVLIRF 252
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 176 bits (428), Expect = 1e-43
Identities = 106/258 (41%), Positives = 152/258 (58%), Gaps = 13/258 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 321 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
G A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 498 ------MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 644
F D + + + LDTW M + GL K+IGISNFN Q++ I+ G
Sbjct: 116 FRPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILSKPG 175
Query: 645 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERL 821
L+ KP+ QIE + L Q +L ++C+ IVV AY+P GS A+P P ++D R+
Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKP-EDPSLLEDPRI 234
Query: 822 VGIAQKYNKTVPQVALRF 875
IA K+NKT QV +RF
Sbjct: 235 KAIAAKHNKTTAQVLIRF 252
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 175 bits (427), Expect = 1e-43
Identities = 105/256 (41%), Positives = 152/256 (59%), Gaps = 13/256 (5%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 326
L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++VG
Sbjct: 7 LNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEVGV 57
Query: 327 ALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA-- 497
A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 58 AIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFK 117
Query: 498 ----MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE 650
F D + + + LDTW M + GL K+IGISNFN Q++ I++ GL+
Sbjct: 118 PGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLK 177
Query: 651 -KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVG 827
KP+ QIE + L Q +L ++C+ IVV AY+P GS A+P P ++D R+
Sbjct: 178 YKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKP-EDPSLLEDPRIKA 236
Query: 828 IAQKYNKTVPQVALRF 875
IA K+NKT QV +RF
Sbjct: 237 IAAKHNKTTAQVLIRF 252
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 173 bits (421), Expect = 7e-43
Identities = 102/259 (39%), Positives = 152/259 (58%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 495 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
++ EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + Q +L FC+ DIV++AY+ GS P ++D
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 173 bits (421), Expect = 7e-43
Identities = 102/259 (39%), Positives = 152/259 (58%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 495 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
++ EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + Q +L FC+ DIV++AY+ GS P ++D
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 173 bits (421), Expect = 7e-43
Identities = 102/259 (39%), Positives = 152/259 (58%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 495 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
++ EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + Q +L FC+ DIV++AY+ GS P ++D
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 173 bits (421), Expect = 7e-43
Identities = 102/259 (39%), Positives = 152/259 (58%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 495 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
++ EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + Q +L FC+ DIV++AY+ GS P ++D
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 173 bits (421), Expect = 7e-43
Identities = 102/259 (39%), Positives = 152/259 (58%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 495 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
++ EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + Q +L FC+ DIV++AY+ GS P ++D
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 173 bits (421), Expect = 7e-43
Identities = 102/259 (39%), Positives = 152/259 (58%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 495 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
++ EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + Q +L FC+ DIV++AY+ GS P ++D
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 173 bits (421), Expect = 7e-43
Identities = 102/259 (39%), Positives = 152/259 (58%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 495 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
++ EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + Q +L FC+ DIV++AY+ GS P ++D
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 173 bits (421), Expect = 7e-43
Identities = 102/259 (39%), Positives = 152/259 (58%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 495 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
++ EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + Q +L FC+ DIV++AY+ GS P ++D
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 173 bits (421), Expect = 7e-43
Identities = 102/259 (39%), Positives = 152/259 (58%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 495 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
++ EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + Q +L FC+ DIV++AY+ GS P ++D
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 173 bits (421), Expect = 7e-43
Identities = 102/259 (39%), Positives = 152/259 (58%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 495 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
++ EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + Q +L FC+ DIV++AY+ GS P ++D
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 173 bits (420), Expect = 9e-43
Identities = 103/259 (39%), Positives = 152/259 (58%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 495 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
++ EN +L D VD TW M K GL KSIG+SNFN ++ I++
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + Q +L FC+ DIV++AY+ GS P ++D
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 173 bits (420), Expect = 9e-43
Identities = 103/259 (39%), Positives = 152/259 (58%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 495 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
++ EN +L D VD TW M K GL KSIG+SNFN ++ I++
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + Q +L FC+ DIV++AY+ GS P ++D
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 173 bits (420), Expect = 9e-43
Identities = 103/259 (39%), Positives = 152/259 (58%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 495 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
++ EN +L D VD TW M K GL KSIG+SNFN ++ I++
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + Q +L FC+ DIV++AY+ GS P ++D
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 173 bits (420), Expect = 9e-43
Identities = 103/259 (39%), Positives = 152/259 (58%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 495 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
++ EN +L D VD TW M K GL KSIG+SNFN ++ I++
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + Q +L FC+ DIV++AY+ GS P ++D
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 173 bits (420), Expect = 9e-43
Identities = 103/259 (39%), Positives = 152/259 (58%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 495 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
++ EN +L D VD TW M K GL KSIG+SNFN ++ I++
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + Q +L FC+ DIV++AY+ GS P ++D
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 173 bits (420), Expect = 9e-43
Identities = 103/259 (39%), Positives = 152/259 (58%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 495 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
++ EN +L D VD TW M K GL KSIG+SNFN ++ I++
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + Q +L FC+ DIV++AY+ GS P ++D
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 173 bits (420), Expect = 9e-43
Identities = 103/259 (39%), Positives = 152/259 (58%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 495 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
++ EN +L D VD TW M K GL KSIG+SNFN ++ I++
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + Q +L FC+ DIV++AY+ GS P ++D
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 173 bits (420), Expect = 9e-43
Identities = 103/259 (39%), Positives = 152/259 (58%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 495 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
++ EN +L D VD TW M K GL KSIG+SNFN ++ I++
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + Q +L FC+ DIV++AY+ GS P ++D
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 173 bits (420), Expect = 9e-43
Identities = 103/259 (39%), Positives = 152/259 (58%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 495 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
++ EN +L D VD TW M K GL KSIG+SNFN ++ I++
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + Q +L FC+ DIV++AY+ GS P ++D
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 171 bits (417), Expect = 2e-42
Identities = 101/258 (39%), Positives = 147/258 (56%), Gaps = 13/258 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
++LS+ +P+V LGTW P GKV ++AV A++AGY HID AY Y E +V
Sbjct: 5 VELSTKAKMPIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 321 GRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
G A+ +K E +KRE +FI +KLW ++ ER V A K+L++L L Y+D+YLIHWP
Sbjct: 56 GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115
Query: 498 MFENDTLLDNVD----------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 644
D L D FLD W M + GL K++G+SNF+ QI+++++ G
Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175
Query: 645 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERL 821
L+ KP Q+E + L Q +L ++C I V AY+P GS A+P P ++D ++
Sbjct: 176 LKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKP-EDPSLLEDPKI 234
Query: 822 VGIAQKYNKTVPQVALRF 875
IA K+ KT QV +RF
Sbjct: 235 KEIAAKHKKTAAQVLIRF 252
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 171 bits (417), Expect = 2e-42
Identities = 101/258 (39%), Positives = 147/258 (56%), Gaps = 13/258 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
++LS+ +P+V LGTW P GKV ++AV A++AGY HID AY Y E +V
Sbjct: 5 VELSTKAKMPIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 321 GRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
G A+ +K E +KRE +FI +KLW ++ ER V A K+L++L L Y+D+YLIHWP
Sbjct: 56 GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115
Query: 498 MFENDTLLDNVD----------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 644
D L D FLD W M + GL K++G+SNF+ QI+++++ G
Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175
Query: 645 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERL 821
L+ KP Q+E + L Q +L ++C I V AY+P GS A+P P ++D ++
Sbjct: 176 LKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKP-EDPSLLEDPKI 234
Query: 822 VGIAQKYNKTVPQVALRF 875
IA K+ KT QV +RF
Sbjct: 235 KEIAAKHKKTAAQVLIRF 252
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 171 bits (417), Expect = 2e-42
Identities = 101/258 (39%), Positives = 147/258 (56%), Gaps = 13/258 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
++LS+ +P+V LGTW P GKV ++AV A++AGY HID AY Y E +V
Sbjct: 5 VELSTKAKMPIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 321 GRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
G A+ +K E +KRE +FI +KLW ++ ER V A K+L++L L Y+D+YLIHWP
Sbjct: 56 GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115
Query: 498 MFENDTLLDNVD----------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 644
D L D FLD W M + GL K++G+SNF+ QI+++++ G
Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175
Query: 645 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERL 821
L+ KP Q+E + L Q +L ++C I V AY+P GS A+P P ++D ++
Sbjct: 176 LKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKP-EDPSLLEDPKI 234
Query: 822 VGIAQKYNKTVPQVALRF 875
IA K+ KT QV +RF
Sbjct: 235 KEIAAKHKKTAAQVLIRF 252
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 171 bits (417), Expect = 2e-42
Identities = 101/258 (39%), Positives = 147/258 (56%), Gaps = 13/258 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
++LS+ +P+V LGTW P GKV ++AV A++AGY HID AY Y E +V
Sbjct: 5 VELSTKAKMPIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 321 GRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
G A+ +K E +KRE +FI +KLW ++ ER V A K+L++L L Y+D+YLIHWP
Sbjct: 56 GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115
Query: 498 MFENDTLLDNVD----------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 644
D L D FLD W M + GL K++G+SNF+ QI+++++ G
Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175
Query: 645 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERL 821
L+ KP Q+E + L Q +L ++C I V AY+P GS A+P P ++D ++
Sbjct: 176 LKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKP-EDPSLLEDPKI 234
Query: 822 VGIAQKYNKTVPQVALRF 875
IA K+ KT QV +RF
Sbjct: 235 KEIAAKHKKTAAQVLIRF 252
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 171 bits (417), Expect = 2e-42
Identities = 101/258 (39%), Positives = 147/258 (56%), Gaps = 13/258 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
++LS+ +P+V LGTW P GKV ++AV A++AGY HID AY Y E +V
Sbjct: 5 VELSTKAKMPIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 321 GRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
G A+ +K E +KRE +FI +KLW ++ ER V A K+L++L L Y+D+YLIHWP
Sbjct: 56 GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115
Query: 498 MFENDTLLDNVD----------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 644
D L D FLD W M + GL K++G+SNF+ QI+++++ G
Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175
Query: 645 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERL 821
L+ KP Q+E + L Q +L ++C I V AY+P GS A+P P ++D ++
Sbjct: 176 LKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKP-EDPSLLEDPKI 234
Query: 822 VGIAQKYNKTVPQVALRF 875
IA K+ KT QV +RF
Sbjct: 235 KEIAAKHKKTAAQVLIRF 252
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 171 bits (417), Expect = 2e-42
Identities = 104/254 (40%), Positives = 150/254 (59%), Gaps = 13/254 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 2 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 52
Query: 321 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
G A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 53 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 112
Query: 498 ------MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 644
F D + + + LDTW M + GL K+IGISNFN Q++ I++ G
Sbjct: 113 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 172
Query: 645 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERL 821
L+ KP+ QIE + L Q +L ++C+ IVV AY+P GS A+P P ++D R+
Sbjct: 173 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKP-EDPSLLEDPRI 231
Query: 822 VGIAQKYNKTVPQV 863
IA K+NKT QV
Sbjct: 232 KAIAAKHNKTTAQV 245
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 171 bits (416), Expect = 3e-42
Identities = 102/259 (39%), Positives = 152/259 (58%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 495 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII-DS 641
++ EN +L D VD TW M K GL KSIG+SNFN ++ I+ +
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ +P Q+E + Q +L FC+ DIV++AY+ GS P ++D
Sbjct: 181 GLKYEPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 171 bits (416), Expect = 3e-42
Identities = 102/259 (39%), Positives = 151/259 (58%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ PK K ++ AV A+EAGY HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGYHHIDSAHVYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+Y DLYLIH+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYADLYLIHFPV 120
Query: 495 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII-DS 641
++ EN +L D VD TW M K GL KSIG+SNFN ++ I+ +
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ +P Q+E + Q +L FC+ DIV++AY+ GS P ++D
Sbjct: 181 GLKYEPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 171 bits (415), Expect = 4e-42
Identities = 105/258 (40%), Positives = 152/258 (58%), Gaps = 13/258 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 321 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
G A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 498 ------MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 644
F D + + + LDT M + GL K+IGISNFN Q++ I++ G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTRAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175
Query: 645 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERL 821
L+ KP+ QIE + L Q +L ++C+ IVV AY+P GS A+P P ++D R+
Sbjct: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKP-EDPSLLEDPRI 234
Query: 822 VGIAQKYNKTVPQVALRF 875
IA K+NKT QV +RF
Sbjct: 235 KAIAAKHNKTTAQVLIRF 252
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 170 bits (413), Expect = 7e-42
Identities = 98/259 (37%), Positives = 150/259 (57%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q
Sbjct: 10 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 62
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW+++H E V PAL SL+ L+YVDLYLIH P+
Sbjct: 63 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 122
Query: 495 AMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
++ + L D VD TW M K GL KSIG+SNFN+ Q++ I++
Sbjct: 123 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 182
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + + +L FC+ DIV++AY+ GS + P ++D
Sbjct: 183 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 242
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 243 LCALAKKHKRTPALIALRY 261
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 170 bits (413), Expect = 7e-42
Identities = 98/259 (37%), Positives = 150/259 (57%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW+++H E V PAL SL+ L+YVDLYLIH P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120
Query: 495 AMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
++ + L D VD TW M K GL KSIG+SNFN+ Q++ I++
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + + +L FC+ DIV++AY+ GS + P ++D
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 170 bits (413), Expect = 7e-42
Identities = 98/259 (37%), Positives = 150/259 (57%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW+++H E V PAL SL+ L+YVDLYLIH P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120
Query: 495 AMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
++ + L D VD TW M K GL KSIG+SNFN+ Q++ I++
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + + +L FC+ DIV++AY+ GS + P ++D
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 170 bits (413), Expect = 7e-42
Identities = 98/259 (37%), Positives = 150/259 (57%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW+++H E V PAL SL+ L+YVDLYLIH P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120
Query: 495 AMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
++ + L D VD TW M K GL KSIG+SNFN+ Q++ I++
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + + +L FC+ DIV++AY+ GS + P ++D
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 170 bits (413), Expect = 7e-42
Identities = 98/259 (37%), Positives = 150/259 (57%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW+++H E V PAL SL+ L+YVDLYLIH P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120
Query: 495 AMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
++ + L D VD TW M K GL KSIG+SNFN+ Q++ I++
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + + +L FC+ DIV++AY+ GS + P ++D
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 170 bits (413), Expect = 7e-42
Identities = 98/259 (37%), Positives = 150/259 (57%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW+++H E V PAL SL+ L+YVDLYLIH P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120
Query: 495 AMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
++ + L D VD TW M K GL KSIG+SNFN+ Q++ I++
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + + +L FC+ DIV++AY+ GS + P ++D
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 170 bits (413), Expect = 7e-42
Identities = 98/259 (37%), Positives = 150/259 (57%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW+++H E V PAL SL+ L+YVDLYLIH P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120
Query: 495 AMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
++ + L D VD TW M K GL KSIG+SNFN+ Q++ I++
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + + +L FC+ DIV++AY+ GS + P ++D
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 169 bits (412), Expect = 9e-42
Identities = 98/259 (37%), Positives = 151/259 (58%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+Q
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW ++ + + V PAL SL+ L L+YVDLYL+H+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120
Query: 495 AMFENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
A+ +T + D VD TW M K GL KSIG+SNFN Q++ I++
Sbjct: 121 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + L Q +L FC+ DIV++A++ G+ P ++D
Sbjct: 181 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 169 bits (411), Expect = 1e-41
Identities = 98/259 (37%), Positives = 151/259 (58%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+Q
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW ++ + + V PAL SL+ L L+YVDLYL+H+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120
Query: 495 AMFENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
A+ +T + D VD TW M K GL KSIG+SNFN Q++ I++
Sbjct: 121 ALKPGETPLPKDENGKVIFDTVDLCATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + L Q +L FC+ DIV++A++ G+ P ++D
Sbjct: 181 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 169 bits (410), Expect = 2e-41
Identities = 98/259 (37%), Positives = 151/259 (58%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+Q
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW ++ + + V PAL SL+ L L+YVDLYL+H+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120
Query: 495 AMFENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
A+ +T + D VD TW M K GL KSIG+SNFN Q++ I++
Sbjct: 121 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + L Q +L FC+ DIV++A++ G+ P ++D
Sbjct: 181 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 169 bits (410), Expect = 2e-41
Identities = 98/259 (37%), Positives = 151/259 (58%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+Q
Sbjct: 6 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 58
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW ++ + + V PAL SL+ L L+YVDLYL+H+P+
Sbjct: 59 VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 118
Query: 495 AMFENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
A+ +T + D VD TW M K GL KSIG+SNFN Q++ I++
Sbjct: 119 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP 178
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + L Q +L FC+ DIV++A++ G+ P ++D
Sbjct: 179 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV 238
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 239 LCALAKKHKRTPALIALRY 257
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 169 bits (410), Expect = 2e-41
Identities = 100/258 (38%), Positives = 146/258 (56%), Gaps = 13/258 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
++LS+ +P+V LGTW P GKV ++AV A++AGY HID AY Y E +V
Sbjct: 5 VELSTKAKMPIVGLGTWKS--PLGKV-------KEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 321 GRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
G A+ +K E +KRE +FI +KLW ++ ER V A K+L++ L Y+D+YLIHWP
Sbjct: 56 GEAIQEKIQEKAVKREDLFIASKLWPTFFERPLVRKAFEKTLKDPKLSYLDVYLIHWPQG 115
Query: 498 MFENDTLLDNVD----------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 644
D L D FLD W M + GL K++G+SNF+ QI+++++ G
Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175
Query: 645 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERL 821
L+ KP Q+E + L Q +L ++C I V AY+P GS A+P P ++D ++
Sbjct: 176 LKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKP-EDPSLLEDPKI 234
Query: 822 VGIAQKYNKTVPQVALRF 875
IA K+ KT QV +RF
Sbjct: 235 KEIAAKHKKTAAQVLIRF 252
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 169 bits (410), Expect = 2e-41
Identities = 98/259 (37%), Positives = 151/259 (58%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+Q
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW ++ + + V PAL SL+ L L+YVDLYL+H+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120
Query: 495 AMFENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
A+ +T + D VD TW M K GL KSIG+SNFN Q++ I++
Sbjct: 121 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + L Q +L FC+ DIV++A++ G+ P ++D
Sbjct: 181 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 169 bits (410), Expect = 2e-41
Identities = 98/259 (37%), Positives = 151/259 (58%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+Q
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW ++ + + V PAL SL+ L L+YVDLYL+H+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120
Query: 495 AMFENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
A+ +T + D VD TW M K GL KSIG+SNFN Q++ I++
Sbjct: 121 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + L Q +L FC+ DIV++A++ G+ P ++D
Sbjct: 181 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 168 bits (409), Expect = 2e-41
Identities = 98/259 (37%), Positives = 151/259 (58%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+Q
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW ++ + + V PAL SL+ L L+YVDLYL+H+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120
Query: 495 AMFENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
A+ +T + D VD TW M K GL KSIG+SNFN Q++ I++
Sbjct: 121 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + L Q +L FC+ DIV++A++ G+ P ++D
Sbjct: 181 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKQTPALIALRY 259
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 168 bits (408), Expect = 3e-41
Identities = 99/258 (38%), Positives = 147/258 (56%), Gaps = 13/258 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
+ LS G +IP++ LGT+ + K T+ V A++ GY HID AY Y E +V
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATS-----VKVAIDTGYRHIDGAYIYQNEHEV 64
Query: 321 GRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
G A+ +K +EG ++RE IF KLW + H E V P L ++L L L+YVDLY+I P+A
Sbjct: 65 GEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMA 124
Query: 498 MFENDTLL---DNVDFL-------DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 644
D + +N +L TW M K GL KS+G+SNFN+ Q++ I++ G
Sbjct: 125 FKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPG 184
Query: 645 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERL 821
L+ KP + Q+E + QP+L KFC+++DIV+ AY+P G+ + PP + D L
Sbjct: 185 LKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALL 244
Query: 822 VGIAQKYNKTVPQVALRF 875
+ ++YNKT Q+ LRF
Sbjct: 245 NSLGKRYNKTAAQIVLRF 262
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 168 bits (408), Expect = 3e-41
Identities = 100/259 (38%), Positives = 150/259 (57%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 5 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 57
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW + H E PAL +SL+NL L+YVDLYLIH+P+
Sbjct: 58 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELDRPALERSLKNLQLDYVDLYLIHFPV 117
Query: 495 AM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
++ EN +L D VD TW + K L KSIG+SNFN+ ++ I++
Sbjct: 118 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAELAKSIGVSNFNRSTLEMILNKP 177
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + Q +L FC+ DIV++AY+ GSL P ++D
Sbjct: 178 GLQVKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSLREEPWVDPNSPVLLEDPV 237
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 238 LCALAKKHKRTPALIALRY 256
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 168 bits (408), Expect = 3e-41
Identities = 99/258 (38%), Positives = 147/258 (56%), Gaps = 13/258 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
+ LS G +IP++ LGT+ + K T+ V A++ GY HID AY Y E +V
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATS-----VKVAIDTGYRHIDGAYIYQNEHEV 64
Query: 321 GRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
G A+ +K +EG ++RE IF KLW + H E V P L ++L L L+YVDLY+I P+A
Sbjct: 65 GEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMA 124
Query: 498 MFENDTLL---DNVDFL-------DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 644
D + +N +L TW M K GL KS+G+SNFN+ Q++ I++ G
Sbjct: 125 FKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPG 184
Query: 645 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERL 821
L+ KP + Q+E + QP+L KFC+++DIV+ AY+P G+ + PP + D L
Sbjct: 185 LKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALL 244
Query: 822 VGIAQKYNKTVPQVALRF 875
+ ++YNKT Q+ LRF
Sbjct: 245 NSLGKRYNKTAAQIVLRF 262
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 168 bits (408), Expect = 3e-41
Identities = 99/258 (38%), Positives = 147/258 (56%), Gaps = 13/258 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
+ LS G +IP++ LGT+ + K T+ V A++ GY HID AY Y E +V
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATS-----VKVAIDTGYRHIDGAYIYQNEHEV 64
Query: 321 GRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
G A+ +K +EG ++RE IF KLW + H E V P L ++L L L+YVDLY+I P+A
Sbjct: 65 GEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMA 124
Query: 498 MFENDTLL---DNVDFL-------DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 644
D + +N +L TW M K GL KS+G+SNFN+ Q++ I++ G
Sbjct: 125 FKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPG 184
Query: 645 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERL 821
L+ KP + Q+E + QP+L KFC+++DIV+ AY+P G+ + PP + D L
Sbjct: 185 LKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALL 244
Query: 822 VGIAQKYNKTVPQVALRF 875
+ ++YNKT Q+ LRF
Sbjct: 245 NSLGKRYNKTAAQIVLRF 262
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 168 bits (408), Expect = 3e-41
Identities = 99/258 (38%), Positives = 147/258 (56%), Gaps = 13/258 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 320
+ LS G +IP++ LGT+ + K T+ V A++ GY HID AY Y E +V
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATS-----VKVAIDTGYRHIDGAYIYQNEHEV 64
Query: 321 GRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 497
G A+ +K +EG ++RE IF KLW + H E V P L ++L L L+YVDLY+I P+A
Sbjct: 65 GEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMA 124
Query: 498 MFENDTLL---DNVDFL-------DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 644
D + +N +L TW M K GL KS+G+SNFN+ Q++ I++ G
Sbjct: 125 FKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPG 184
Query: 645 LE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERL 821
L+ KP + Q+E + QP+L KFC+++DIV+ AY+P G+ + PP + D L
Sbjct: 185 LKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALL 244
Query: 822 VGIAQKYNKTVPQVALRF 875
+ ++YNKT Q+ LRF
Sbjct: 245 NSLGKRYNKTAAQIVLRF 262
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 167 bits (407), Expect = 4e-41
Identities = 97/259 (37%), Positives = 150/259 (57%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G ++RE IF T+KLW+++H E V PAL SL+ L+YVDLYLIH P+
Sbjct: 61 VGLAIRSKIADGSVEREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120
Query: 495 AMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
++ + L D VD TW M K GL KSIG+SNFN+ Q++ I++
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + + +L FC+ DIV++AY+ GS + P ++D
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 167 bits (405), Expect = 6e-41
Identities = 97/259 (37%), Positives = 149/259 (57%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ P+ K ++VT A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G + RE IF T+KLW+++H E V PAL SL+ L+YVDLYLIH P+
Sbjct: 61 VGLAIRSKIADGSVMREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120
Query: 495 AMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
++ + L D VD TW M K GL KSIG+SNFN+ Q++ I++
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + + +L FC+ DIV++AY+ GS + P ++D
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 167 bits (405), Expect = 6e-41
Identities = 99/249 (39%), Positives = 145/249 (58%), Gaps = 14/249 (5%)
Frame = +3
Query: 171 VVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFS 347
V+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+QVG A+ K +
Sbjct: 1 VLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQVGLAIRSKIA 53
Query: 348 EG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM-------- 500
+G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P+++
Sbjct: 54 DGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIP 113
Query: 501 -FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQ 668
EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++ GL+ KP Q
Sbjct: 114 KDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQ 173
Query: 669 IELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNK 848
+E + Q +L FC+ DIV++AY+ GS P ++D L +A+K+ +
Sbjct: 174 VECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKR 233
Query: 849 TVPQVALRF 875
T +ALR+
Sbjct: 234 TPALIALRY 242
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 167 bits (405), Expect = 6e-41
Identities = 98/259 (37%), Positives = 148/259 (57%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ PK K ++ T A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW + H E V PAL +SL+ L+YVDLYLIH P+
Sbjct: 61 VGLAVRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKKAQLDYVDLYLIHSPM 120
Query: 495 AMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
++ + L D VD TW M K GL KSIG+SNFN+ Q++ I++
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + + +L FC+ DIV++AY+ GS + P ++D
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 166 bits (404), Expect = 8e-41
Identities = 97/259 (37%), Positives = 149/259 (57%), Gaps = 14/259 (5%)
Frame = +3
Query: 141 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
++L+ G +PV+ GT+ P+ K ++V+ A+EAG+ HID+A+ Y E+Q
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVSK-------LAIEAGFRHIDSAHLYNNEEQ 60
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
VG A+ K ++G +KRE IF T+KLW++ H E V PAL SL+ L+YVDLYLIH P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSTSHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120
Query: 495 AMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS- 641
++ + L D VD TW M K GL KSIG+SNFN+ Q++ I++
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 642 GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDER 818
GL+ KP Q+E + + +L FC+ DIV++AY+ GS + P ++D
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
Query: 819 LVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 241 LCALAKKHKRTPALIALRY 259
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 165 bits (401), Expect = 2e-40
Identities = 96/251 (38%), Positives = 146/251 (58%), Gaps = 14/251 (5%)
Frame = +3
Query: 165 IPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKK 341
+PV+ GT+ P+ + V+VT A+EAG+ HID+AY Y E+QVG A+ K
Sbjct: 1 MPVLGFGTYAPPEVPRNRAVEVTK-------LAIEAGFRHIDSAYLYNNEEQVGLAIRSK 53
Query: 342 FSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDT- 515
++G +KRE IF T+KLW ++ + + V PAL SL+ L L+YVDLYL+H+P+A+ +T
Sbjct: 54 IADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETP 113
Query: 516 ---------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSA 662
+ D VD TW M K GL KSIG+SNFN Q++ I++ GL+ KP
Sbjct: 114 LPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVC 173
Query: 663 LQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKY 842
Q+E + L Q +L FC+ DIV++A++ G+ P ++D L +A+K+
Sbjct: 174 NQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKH 233
Query: 843 NKTVPQVALRF 875
+T +ALR+
Sbjct: 234 KRTPALIALRY 244
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 165 bits (401), Expect = 2e-40
Identities = 94/255 (36%), Positives = 141/255 (55%), Gaps = 12/255 (4%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 326
L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G
Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58
Query: 327 ALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 500
AL + G + RE +F+T+KLWN+ H E V PALRK+L +L LEY+DLYL+HWP A
Sbjct: 59 ALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118
Query: 501 FENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 650
D D+ + +TW+ + GL +++G+SNFN QI I+
Sbjct: 119 ERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV 178
Query: 651 KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGI 830
+P+ LQ+E + L Q EL C+ + V AY+P GS + P P +++ ++ +
Sbjct: 179 RPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPD-EPVLLEEPVVLAL 237
Query: 831 AQKYNKTVPQVALRF 875
A+KY ++ Q+ LR+
Sbjct: 238 AEKYGRSPAQILLRW 252
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 165 bits (401), Expect = 2e-40
Identities = 94/255 (36%), Positives = 141/255 (55%), Gaps = 12/255 (4%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 326
L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G
Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58
Query: 327 ALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 500
AL + G + RE +F+T+KLWN+ H E V PALRK+L +L LEY+DLYL+HWP A
Sbjct: 59 ALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118
Query: 501 FENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 650
D D+ + +TW+ + GL +++G+SNFN QI I+
Sbjct: 119 ERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV 178
Query: 651 KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGI 830
+P+ LQ+E + L Q EL C+ + V AY+P GS + P P +++ ++ +
Sbjct: 179 RPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPD-EPVLLEEPVVLAL 237
Query: 831 AQKYNKTVPQVALRF 875
A+KY ++ Q+ LR+
Sbjct: 238 AEKYGRSPAQILLRW 252
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 165 bits (401), Expect = 2e-40
Identities = 94/255 (36%), Positives = 141/255 (55%), Gaps = 12/255 (4%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 326
L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G
Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58
Query: 327 ALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 500
AL + G + RE +F+T+KLWN+ H E V PALRK+L +L LEY+DLYL+HWP A
Sbjct: 59 ALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118
Query: 501 FENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 650
D D+ + +TW+ + GL +++G+SNFN QI I+
Sbjct: 119 ERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV 178
Query: 651 KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGI 830
+P+ LQ+E + L Q EL C+ + V AY+P GS + P P +++ ++ +
Sbjct: 179 RPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPD-EPVLLEEPVVLAL 237
Query: 831 AQKYNKTVPQVALRF 875
A+KY ++ Q+ LR+
Sbjct: 238 AEKYGRSPAQILLRW 252
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 165 bits (401), Expect = 2e-40
Identities = 94/255 (36%), Positives = 141/255 (55%), Gaps = 12/255 (4%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 326
L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G
Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58
Query: 327 ALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 500
AL + G + RE +F+T+KLWN+ H E V PALRK+L +L LEY+DLYL+HWP A
Sbjct: 59 ALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118
Query: 501 FENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 650
D D+ + +TW+ + GL +++G+SNFN QI I+
Sbjct: 119 ERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV 178
Query: 651 KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGI 830
+P+ LQ+E + L Q EL C+ + V AY+P GS + P P +++ ++ +
Sbjct: 179 RPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPD-EPVLLEEPVVLAL 237
Query: 831 AQKYNKTVPQVALRF 875
A+KY ++ Q+ LR+
Sbjct: 238 AEKYGRSPAQILLRW 252
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 165 bits (401), Expect = 2e-40
Identities = 94/255 (36%), Positives = 141/255 (55%), Gaps = 12/255 (4%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 326
L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G
Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58
Query: 327 ALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 500
AL + G + RE +F+T+KLWN+ H E V PALRK+L +L LEY+DLYL+HWP A
Sbjct: 59 ALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118
Query: 501 FENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 650
D D+ + +TW+ + GL +++G+SNFN QI I+
Sbjct: 119 ERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV 178
Query: 651 KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGI 830
+P+ LQ+E + L Q EL C+ + V AY+P GS + P P +++ ++ +
Sbjct: 179 RPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPD-EPVLLEEPVVLAL 237
Query: 831 AQKYNKTVPQVALRF 875
A+KY ++ Q+ LR+
Sbjct: 238 AEKYGRSPAQILLRW 252
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 165 bits (401), Expect = 2e-40
Identities = 94/255 (36%), Positives = 141/255 (55%), Gaps = 12/255 (4%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 326
L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G
Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58
Query: 327 ALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 500
AL + G + RE +F+T+KLWN+ H E V PALRK+L +L LEY+DLYL+HWP A
Sbjct: 59 ALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118
Query: 501 FENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 650
D D+ + +TW+ + GL +++G+SNFN QI I+
Sbjct: 119 ERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV 178
Query: 651 KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGI 830
+P+ LQ+E + L Q EL C+ + V AY+P GS + P P +++ ++ +
Sbjct: 179 RPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPD-EPVLLEEPVVLAL 237
Query: 831 AQKYNKTVPQVALRF 875
A+KY ++ Q+ LR+
Sbjct: 238 AEKYGRSPAQILLRW 252
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 165 bits (401), Expect = 2e-40
Identities = 94/255 (36%), Positives = 141/255 (55%), Gaps = 12/255 (4%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 326
L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G
Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58
Query: 327 ALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 500
AL + G + RE +F+T+KLWN+ H E V PALRK+L +L LEY+DLYL+HWP A
Sbjct: 59 ALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118
Query: 501 FENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 650
D D+ + +TW+ + GL +++G+SNFN QI I+
Sbjct: 119 ERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV 178
Query: 651 KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGI 830
+P+ LQ+E + L Q EL C+ + V AY+P GS + P P +++ ++ +
Sbjct: 179 RPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPD-EPVLLEEPVVLAL 237
Query: 831 AQKYNKTVPQVALRF 875
A+KY ++ Q+ LR+
Sbjct: 238 AEKYGRSPAQILLRW 252
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 165 bits (401), Expect = 2e-40
Identities = 94/255 (36%), Positives = 141/255 (55%), Gaps = 12/255 (4%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 326
L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G
Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58
Query: 327 ALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 500
AL + G + RE +F+T+KLWN+ H E V PALRK+L +L LEY+DLYL+HWP A
Sbjct: 59 ALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118
Query: 501 FENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 650
D D+ + +TW+ + GL +++G+SNFN QI I+
Sbjct: 119 ERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV 178
Query: 651 KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGI 830
+P+ LQ+E + L Q EL C+ + V AY+P GS + P P +++ ++ +
Sbjct: 179 RPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPD-EPVLLEEPVVLAL 237
Query: 831 AQKYNKTVPQVALRF 875
A+KY ++ Q+ LR+
Sbjct: 238 AEKYGRSPAQILLRW 252
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 164 bits (399), Expect = 3e-40
Identities = 101/256 (39%), Positives = 146/256 (57%), Gaps = 14/256 (5%)
Frame = +3
Query: 114 TSADLIVPTLQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDT 290
T D ++L+ G +PV+ GT+ PK K ++ AV A+EAG+ HID+
Sbjct: 12 TEMDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALE-------AVKLAIEAGFHHIDS 64
Query: 291 AYKYGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 467
A+ Y E+QVG A+ K ++G +KRE IF T+KLW++ H E V PAL +SL+NL L+YV
Sbjct: 65 AHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYV 124
Query: 468 DLYLIHWPIAM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQE 617
DLYLIH+P+++ EN +L D VD TW M K GL KSIG+SNFN
Sbjct: 125 DLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHR 184
Query: 618 QIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXA 791
++ I++ GL+ KP Q+E + Q +L FC+ DIV++AY+ GS
Sbjct: 185 LLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPN 244
Query: 792 PPPRIDDERLVGIAQK 839
P ++D L +A+K
Sbjct: 245 SPVLLEDPVLCALAKK 260
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 94.7 bits (225), Expect(2) = 1e-36
Identities = 52/113 (46%), Positives = 68/113 (60%), Gaps = 1/113 (0%)
Frame = +3
Query: 159 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 338
G+IP V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 339 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
K EG ++RE +FI TKLW + H++ V A RKSL+ L L Y+DLYLIHWP+
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105
Score = 79.8 bits (188), Expect(2) = 1e-36
Identities = 47/125 (37%), Positives = 67/125 (53%), Gaps = 2/125 (1%)
Frame = +3
Query: 507 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIELN 680
N + + DFLDTW M D GL K+IG+SNFN EQ++R+++ GL KP QIE +
Sbjct: 139 NMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECH 198
Query: 681 LNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQ 860
L Q L FC+ D+ V AY P G ID+ + IA+++ K+ Q
Sbjct: 199 PYLTQKNLISFCQSRDVSVTAYRPLGG-------SCEGVDLIDNPVIKRIAKEHGKSPAQ 251
Query: 861 VALRF 875
+ +RF
Sbjct: 252 ILIRF 256
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 94.7 bits (225), Expect(2) = 1e-36
Identities = 52/113 (46%), Positives = 68/113 (60%), Gaps = 1/113 (0%)
Frame = +3
Query: 159 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 338
G+IP V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 339 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
K EG ++RE +FI TKLW + H++ V A RKSL+ L L Y+DLYLIHWP+
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105
Score = 79.8 bits (188), Expect(2) = 1e-36
Identities = 47/125 (37%), Positives = 67/125 (53%), Gaps = 2/125 (1%)
Frame = +3
Query: 507 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIELN 680
N + + DFLDTW M D GL K+IG+SNFN EQ++R+++ GL KP QIE +
Sbjct: 139 NMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECH 198
Query: 681 LNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQ 860
L Q L FC+ D+ V AY P G ID+ + IA+++ K+ Q
Sbjct: 199 PYLTQKNLISFCQSRDVSVTAYRPLGG-------SCEGVDLIDNPVIKRIAKEHGKSPAQ 251
Query: 861 VALRF 875
+ +RF
Sbjct: 252 ILIRF 256
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 94.7 bits (225), Expect(2) = 1e-36
Identities = 52/113 (46%), Positives = 68/113 (60%), Gaps = 1/113 (0%)
Frame = +3
Query: 159 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 338
G+IP V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 339 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
K EG ++RE +FI TKLW + H++ V A RKSL+ L L Y+DLYLIHWP+
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105
Score = 79.8 bits (188), Expect(2) = 1e-36
Identities = 47/125 (37%), Positives = 67/125 (53%), Gaps = 2/125 (1%)
Frame = +3
Query: 507 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIELN 680
N + + DFLDTW M D GL K+IG+SNFN EQ++R+++ GL KP QIE +
Sbjct: 139 NMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECH 198
Query: 681 LNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDERLVGIAQKYNKTVPQ 860
L Q L FC+ D+ V AY P G ID+ + IA+++ K+ Q
Sbjct: 199 PYLTQKNLISFCQSRDVSVTAYRPLGG-------SCEGVDLIDNPVIKRIAKEHGKSPAQ 251
Query: 861 VALRF 875
+ +RF
Sbjct: 252 ILIRF 256
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 141 bits (341), Expect = 3e-33
Identities = 81/200 (40%), Positives = 119/200 (59%), Gaps = 13/200 (6%)
Frame = +3
Query: 315 QVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 491
+VG A+ K ++G +KRE IF T+KLW + H E V PAL +SL+NL L+YVDLYLIH+P
Sbjct: 26 EVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 85
Query: 492 IAM---------FENDTLL-DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS 641
+++ EN +L D VD TW + K GL KSIG+SNFN+ Q++ I++
Sbjct: 86 VSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNK 145
Query: 642 -GLE-KPSALQIELNLNLQQPELFKFCRENDIVVMAYTPFGSLFPSKAQPXAPPPRIDDE 815
GL+ KP Q+E + Q +L FC+ DIV++AY+ GS P ++D
Sbjct: 146 PGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDP 205
Query: 816 RLVGIAQKYNKTVPQVALRF 875
L +A+K+ +T +ALR+
Sbjct: 206 VLCALAKKHKRTPALIALRY 225
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 94.7 bits (225), Expect(2) = 2e-29
Identities = 52/113 (46%), Positives = 68/113 (60%), Gaps = 1/113 (0%)
Frame = +3
Query: 159 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 338
G+IP V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 339 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
K EG ++RE +FI TKLW + H++ V A RKSL+ L L Y+DLYLIHWP+
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105
Score = 55.6 bits (128), Expect(2) = 2e-29
Identities = 28/65 (43%), Positives = 40/65 (61%), Gaps = 2/65 (3%)
Frame = +3
Query: 507 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIELN 680
N + + DFLDTW M D GL K+IG+SNFN EQ++R+++ GL KP QI +
Sbjct: 139 NMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQILIR 198
Query: 681 LNLQQ 695
+Q+
Sbjct: 199 FQIQR 203
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 94.7 bits (225), Expect(2) = 2e-29
Identities = 52/113 (46%), Positives = 68/113 (60%), Gaps = 1/113 (0%)
Frame = +3
Query: 159 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 338
G+IP V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 339 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
K EG ++RE +FI TKLW + H++ V A RKSL+ L L Y+DLYLIHWP+
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105
Score = 55.6 bits (128), Expect(2) = 2e-29
Identities = 28/65 (43%), Positives = 40/65 (61%), Gaps = 2/65 (3%)
Frame = +3
Query: 507 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIELN 680
N + + DFLDTW M D GL K+IG+SNFN EQ++R+++ GL KP QI +
Sbjct: 139 NMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQILIR 198
Query: 681 LNLQQ 695
+Q+
Sbjct: 199 FQIQR 203
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 121 bits (292), Expect = 3e-27
Identities = 86/261 (32%), Positives = 138/261 (52%), Gaps = 15/261 (5%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 314
+++L+ G +PV+ GT+ H PK + + T A++ G+ HID+AY Y E+
Sbjct: 10 SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEE 62
Query: 315 QVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 491
+VG+A+ +K ++G +KRE IF T KLW ++ E V PAL +SL+ L +YVDL++IH P
Sbjct: 63 EVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVP 122
Query: 492 IAMFE-----------NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 638
AM + + +L+ V+ DTW + K GL
Sbjct: 123 FAMKQPGKELLPKDASGEIILETVELCDTWELELILNKPGLR------------------ 164
Query: 639 SGLEKPSALQ-IELNLNLQQPELFKFCRENDIVVMAYTPFGS-LFPSKAQPXAPPPRIDD 812
KP+ Q +E + L Q +L +FC+ DIV++AY+ GS P P P +++
Sbjct: 165 ---YKPTCNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALGSQRDPQWVDPDC-PHLLEE 220
Query: 813 ERLVGIAQKYNKTVPQVALRF 875
L IA+K++++ QVALR+
Sbjct: 221 PILKSIAKKHSRSPGQVALRY 241
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 121 bits (292), Expect = 3e-27
Identities = 86/261 (32%), Positives = 138/261 (52%), Gaps = 15/261 (5%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 314
+++L+ G +PV+ GT+ H PK + + T A++ G+ HID+AY Y E+
Sbjct: 10 SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEE 62
Query: 315 QVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 491
+VG+A+ +K ++G +KRE IF T KLW ++ E V PAL +SL+ L +YVDL++IH P
Sbjct: 63 EVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVP 122
Query: 492 IAMFE-----------NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 638
AM + + +L+ V+ DTW + K GL
Sbjct: 123 FAMKQPGKELLPKDASGEIILETVELCDTWELELILNKPGLR------------------ 164
Query: 639 SGLEKPSALQ-IELNLNLQQPELFKFCRENDIVVMAYTPFGS-LFPSKAQPXAPPPRIDD 812
KP+ Q +E + L Q +L +FC+ DIV++AY+ GS P P P +++
Sbjct: 165 ---YKPTCNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALGSQRDPQWVDPDC-PHLLEE 220
Query: 813 ERLVGIAQKYNKTVPQVALRF 875
L IA+K++++ QVALR+
Sbjct: 221 PILKSIAKKHSRSPGQVALRY 241
>AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydela) protein.
Length = 147
Score = 108 bits (260), Expect = 2e-23
Identities = 58/124 (46%), Positives = 76/124 (61%), Gaps = 2/124 (1%)
Frame = +3
Query: 147 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 326
L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G
Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58
Query: 327 ALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 500
AL + G + RE +F+T+KLWN+ H E V PALRK+L +L LEY+DLYL+HWP A
Sbjct: 59 ALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118
Query: 501 FEND 512
D
Sbjct: 119 ERGD 122
>BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 97.5 bits (232), Expect = 6e-20
Identities = 50/123 (40%), Positives = 78/123 (63%), Gaps = 2/123 (1%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 314
+++L+ G +PV+ GT+ H PK + + T A++ G+ HID+AY Y E+
Sbjct: 10 SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEE 62
Query: 315 QVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 491
+VG+A+ +K ++G +KRE IF T KLW ++ E V PAL +SL+ L +YVDL++IH P
Sbjct: 63 EVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVP 122
Query: 492 IAM 500
AM
Sbjct: 123 FAM 125
>BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 97.5 bits (232), Expect = 6e-20
Identities = 50/123 (40%), Positives = 78/123 (63%), Gaps = 2/123 (1%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 314
+++L+ G +PV+ GT+ H PK + + T A++ G+ HID+AY Y E+
Sbjct: 10 SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEE 62
Query: 315 QVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 491
+VG+A+ +K ++G +KRE IF T KLW ++ E V PAL +SL+ L +YVDL++IH P
Sbjct: 63 EVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVP 122
Query: 492 IAM 500
AM
Sbjct: 123 FAM 125
>AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ16347 fis, clone TESTI2036288, moderately
similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
Length = 129
Score = 97.5 bits (232), Expect = 6e-20
Identities = 50/123 (40%), Positives = 78/123 (63%), Gaps = 2/123 (1%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 314
+++L+ G +PV+ GT+ H PK + + T A++ G+ HID+AY Y E+
Sbjct: 10 SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEE 62
Query: 315 QVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 491
+VG+A+ +K ++G +KRE IF T KLW ++ E V PAL +SL+ L +YVDL++IH P
Sbjct: 63 EVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVP 122
Query: 492 IAM 500
AM
Sbjct: 123 FAM 125
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 94.7 bits (225), Expect(2) = 2e-19
Identities = 52/113 (46%), Positives = 68/113 (60%), Gaps = 1/113 (0%)
Frame = +3
Query: 159 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 338
G+IP V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 339 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
K EG ++RE +FI TKLW + H++ V A RKSL+ L L Y+DLYLIHWP+
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105
Score = 21.4 bits (43), Expect(2) = 2e-19
Identities = 8/18 (44%), Positives = 11/18 (61%)
Frame = +3
Query: 507 NDTLLDNVDFLDTWRGMI 560
N + + DFLDTW +I
Sbjct: 139 NMVIPSDTDFLDTWEILI 156
>AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto
reductase protein.
Length = 130
Score = 90.2 bits (214), Expect = 9e-18
Identities = 46/122 (37%), Positives = 77/122 (63%), Gaps = 1/122 (0%)
Frame = +3
Query: 138 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 317
+++L+ G +P++ GT + + V ++N E+AV A++ GY HID+AY + E+
Sbjct: 8 SVKLNDGKFMPILGFGTSVARK-----VAMSN-VEEAVQVAIDVGYRHIDSAYTHLNEEG 61
Query: 318 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 494
+G+A+ KK + G +KR+ IF TTK+W ++ E V L SL+ L L Y+DLYL H+P+
Sbjct: 62 IGQAIRKKIANGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPV 121
Query: 495 AM 500
+
Sbjct: 122 PL 123
>AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens
cDNA FLJ25413 fis, clone TST03402, highly similar to
3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ).
Length = 146
Score = 73.7 bits (173), Expect = 8e-13
Identities = 34/75 (45%), Positives = 52/75 (69%), Gaps = 2/75 (2%)
Frame = +3
Query: 543 TWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIELNLNLQQPELFKFC 716
TW M K GL KS+G+SNFN+ Q++ I++ GL+ KP + Q+E + QP+L KFC
Sbjct: 28 TWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFC 87
Query: 717 RENDIVVMAYTPFGS 761
+++DIV+ AY+P G+
Sbjct: 88 QQHDIVITAYSPLGT 102
>U33429-1|AAC50955.1| 367|Homo sapiens K+ channel beta 2 subunit
protein.
Length = 367
Score = 49.2 bits (112), Expect = 2e-05
Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 11/124 (8%)
Frame = +3
Query: 153 SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 320
SG + + LGTW+ Q+T++ EQ + A + G DTA Y E +
Sbjct: 45 SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 99
Query: 321 GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 479
G + KK G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+
Sbjct: 100 GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 156
Query: 480 IHWP 491
+ P
Sbjct: 157 ANRP 160
>CR542287-1|CAG47082.1| 353|Homo sapiens KCNAB2 protein.
Length = 353
Score = 49.2 bits (112), Expect = 2e-05
Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 11/124 (8%)
Frame = +3
Query: 153 SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 320
SG + + LGTW+ Q+T++ EQ + A + G DTA Y E +
Sbjct: 31 SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 85
Query: 321 GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 479
G + KK G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+
Sbjct: 86 GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 142
Query: 480 IHWP 491
+ P
Sbjct: 143 ANRP 146
>BC130413-1|AAI30414.1| 367|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 367
Score = 49.2 bits (112), Expect = 2e-05
Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 11/124 (8%)
Frame = +3
Query: 153 SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 320
SG + + LGTW+ Q+T++ EQ + A + G DTA Y E +
Sbjct: 45 SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 99
Query: 321 GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 479
G + KK G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+
Sbjct: 100 GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 156
Query: 480 IHWP 491
+ P
Sbjct: 157 ANRP 160
>BC126424-1|AAI26425.1| 367|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 367
Score = 49.2 bits (112), Expect = 2e-05
Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 11/124 (8%)
Frame = +3
Query: 153 SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 320
SG + + LGTW+ Q+T++ EQ + A + G DTA Y E +
Sbjct: 45 SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 99
Query: 321 GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 479
G + KK G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+
Sbjct: 100 GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 156
Query: 480 IHWP 491
+ P
Sbjct: 157 ANRP 160
>BC110351-1|AAI10352.1| 395|Homo sapiens KCNAB2 protein protein.
Length = 395
Score = 49.2 bits (112), Expect = 2e-05
Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 11/124 (8%)
Frame = +3
Query: 153 SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 320
SG + + LGTW+ Q+T++ EQ + A + G DTA Y E +
Sbjct: 45 SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 99
Query: 321 GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 479
G + KK G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+
Sbjct: 100 GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 156
Query: 480 IHWP 491
+ P
Sbjct: 157 ANRP 160
>AL035406-6|CAI19886.1| 253|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 253
Score = 49.2 bits (112), Expect = 2e-05
Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 11/124 (8%)
Frame = +3
Query: 153 SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 320
SG + + LGTW+ Q+T++ EQ + A + G DTA Y E +
Sbjct: 45 SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 99
Query: 321 GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 479
G + KK G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+
Sbjct: 100 GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 156
Query: 480 IHWP 491
+ P
Sbjct: 157 ANRP 160
>AL035406-5|CAI19887.1| 254|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 254
Score = 49.2 bits (112), Expect = 2e-05
Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 11/124 (8%)
Frame = +3
Query: 153 SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 320
SG + + LGTW+ Q+T++ EQ + A + G DTA Y E +
Sbjct: 31 SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 85
Query: 321 GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 479
G + KK G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+
Sbjct: 86 GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 142
Query: 480 IHWP 491
+ P
Sbjct: 143 ANRP 146
>AL035406-4|CAC08512.1| 367|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 367
Score = 49.2 bits (112), Expect = 2e-05
Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 11/124 (8%)
Frame = +3
Query: 153 SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 320
SG + + LGTW+ Q+T++ EQ + A + G DTA Y E +
Sbjct: 45 SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 99
Query: 321 GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 479
G + KK G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+
Sbjct: 100 GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 156
Query: 480 IHWP 491
+ P
Sbjct: 157 ANRP 160
>AL035406-3|CAI19885.1| 353|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 2
protein.
Length = 353
Score = 49.2 bits (112), Expect = 2e-05
Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 11/124 (8%)
Frame = +3
Query: 153 SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 320
SG + + LGTW+ Q+T++ EQ + A + G DTA Y E +
Sbjct: 31 SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 85
Query: 321 GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 479
G + KK G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+
Sbjct: 86 GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 142
Query: 480 IHWP 491
+ P
Sbjct: 143 ANRP 146
>AK131252-1|BAD18431.1| 415|Homo sapiens protein ( Homo sapiens
cDNA FLJ16180 fis, clone BRHIP3000240, highly similar
to Homo sapiens potassium channel beta 2 subunit
(HKvbeta2.2) mRNA. ).
Length = 415
Score = 49.2 bits (112), Expect = 2e-05
Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 11/124 (8%)
Frame = +3
Query: 153 SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 320
SG + + LGTW+ Q+T++ EQ + A + G DTA Y E +
Sbjct: 78 SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 132
Query: 321 GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 479
G + KK G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+
Sbjct: 133 GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 189
Query: 480 IHWP 491
+ P
Sbjct: 190 ANRP 193
>AF044253-1|AAB99859.1| 353|Homo sapiens potassium channel beta 2
subunit protein.
Length = 353
Score = 49.2 bits (112), Expect = 2e-05
Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 11/124 (8%)
Frame = +3
Query: 153 SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 320
SG + + LGTW+ Q+T++ EQ + A + G DTA Y E +
Sbjct: 31 SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 85
Query: 321 GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 479
G + KK G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+
Sbjct: 86 GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 142
Query: 480 IHWP 491
+ P
Sbjct: 143 ANRP 146
>AF029749-1|AAB84170.1| 367|Homo sapiens potassium channel beta 2
subunit protein.
Length = 367
Score = 49.2 bits (112), Expect = 2e-05
Identities = 42/124 (33%), Positives = 60/124 (48%), Gaps = 11/124 (8%)
Frame = +3
Query: 153 SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 320
SG + + LGTW+ Q+T++ EQ + A + G DTA Y E +
Sbjct: 45 SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 99
Query: 321 GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 479
G + KK G +R S+ ITTK+ W E R+ +I L+ SLE L LEYVD+
Sbjct: 100 GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVF 156
Query: 480 IHWP 491
+ P
Sbjct: 157 ANRP 160
>CR542264-1|CAG47060.1| 353|Homo sapiens KCNAB2 protein.
Length = 353
Score = 46.8 bits (106), Expect = 1e-04
Identities = 41/124 (33%), Positives = 59/124 (47%), Gaps = 11/124 (8%)
Frame = +3
Query: 153 SGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI---EDQV 320
SG + + LGTW+ Q+T++ EQ + A + G DTA Y E +
Sbjct: 31 SGLRVSCLGLGTWVTFGG-----QITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVL 85
Query: 321 GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDLYL 479
G + KK G +R S+ ITTK+ W E R+ +I L+ SLE LEYVD+
Sbjct: 86 GNIIKKK---GWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERRQLEYVDVVF 142
Query: 480 IHWP 491
+ P
Sbjct: 143 ANRP 146
>AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthase
protein.
Length = 67
Score = 46.0 bits (104), Expect = 2e-04
Identities = 23/49 (46%), Positives = 31/49 (63%), Gaps = 2/49 (4%)
Frame = +3
Query: 516 LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KP 656
+ D VD TW M K GL KSIG+SNFN+ Q++ I++ GL+ KP
Sbjct: 15 IFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKP 63
>BC099634-1|AAH99634.1| 404|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 3
protein.
Length = 404
Score = 45.6 bits (103), Expect = 2e-04
Identities = 41/118 (34%), Positives = 56/118 (47%), Gaps = 11/118 (9%)
Frame = +3
Query: 153 SGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVI-YALEAGYTHIDTAYKYGI---EDQV 320
SG + + LGTW+ Q++++T + V+ A E G DTA Y E +
Sbjct: 86 SGLRVSCLGLGTWVTFGS-----QISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTL 140
Query: 321 GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDL 473
G L K G +R S ITTK+ W E R+ +I LR SLE L L YVD+
Sbjct: 141 GNILKSK---GWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDI 195
>BC096234-1|AAH96234.1| 404|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 3
protein.
Length = 404
Score = 45.6 bits (103), Expect = 2e-04
Identities = 41/118 (34%), Positives = 56/118 (47%), Gaps = 11/118 (9%)
Frame = +3
Query: 153 SGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVI-YALEAGYTHIDTAYKYGI---EDQV 320
SG + + LGTW+ Q++++T + V+ A E G DTA Y E +
Sbjct: 86 SGLRVSCLGLGTWVTFGS-----QISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTL 140
Query: 321 GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDL 473
G L K G +R S ITTK+ W E R+ +I LR SLE L L YVD+
Sbjct: 141 GNILKSK---GWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDI 195
>BC096232-1|AAH96232.1| 404|Homo sapiens potassium voltage-gated
channel, shaker-related subfamily, beta member 3
protein.
Length = 404
Score = 45.6 bits (103), Expect = 2e-04
Identities = 41/118 (34%), Positives = 56/118 (47%), Gaps = 11/118 (9%)
Frame = +3
Query: 153 SGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVI-YALEAGYTHIDTAYKYGI---EDQV 320
SG + + LGTW+ Q++++T + V+ A E G DTA Y E +
Sbjct: 86 SGLRVSCLGLGTWVTFGS-----QISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTL 140
Query: 321 GRALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDL 473
G L K G +R S ITTK+ W E R+ +I LR SLE L L YVD+
Sbjct: 141 GNILKSK---GWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDI 195
>AF016411-1|AAB92499.1| 404|Homo sapiens KCNA3.1B protein.
Length = 404
Score = 44.4 bits (100), Expect = 6e-04
Identities = 40/117 (34%), Positives = 55/117 (47%), Gaps = 11/117 (9%)
Frame = +3
Query: 156 GGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVI-YALEAGYTHIDTAYKYGI---EDQVG 323
G + + LGTW+ Q++++T + V+ A E G DTA Y E +G
Sbjct: 87 GVRVSCLGLGTWVTFGS-----QISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTLG 141
Query: 324 RALTKKFSEGLKRESIFITTKL-WNSYHE------REQVIPALRKSLENLNLEYVDL 473
L K G +R S ITTK+ W E R+ +I LR SLE L L YVD+
Sbjct: 142 NILKSK---GWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDI 195
>AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto
reductase protein.
Length = 45
Score = 37.9 bits (84), Expect = 0.048
Identities = 15/38 (39%), Positives = 23/38 (60%)
Frame = +3
Query: 387 LWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 500
+W ++ E V L SL+ L L Y+DLYL H+P+ +
Sbjct: 1 VWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVPL 38
>AF026947-1|AAC52104.1| 330|Homo sapiens aflatoxin aldehyde
reductase AFAR protein.
Length = 330
Score = 35.5 bits (78), Expect = 0.26
Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 10/187 (5%)
Frame = +3
Query: 246 AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 416
AV LE G+T +DTA+ Y G + + L G R I W+ + +
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89
Query: 417 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 596
V L SL+ L VDL+ +H P ++ T ++ +T + G +G
Sbjct: 90 VRSQLETSLKRLQCPQVDLFYLHTP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140
Query: 597 ISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTPF- 755
+SN+ ++ I +G P+ Q N +Q ELF R + AY P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLA 200
Query: 756 GSLFPSK 776
G L K
Sbjct: 201 GGLLTGK 207
>Y16675-1|CAA76347.1| 330|Homo sapiens aflatoxin B1-aldehyde
reductase protein.
Length = 330
Score = 35.1 bits (77), Expect = 0.34
Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 10/187 (5%)
Frame = +3
Query: 246 AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 416
AV LE G+T +DTA+ Y G + + L G R I W+ + +
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89
Query: 417 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 596
V L SL+ L VDL+ +H P ++ T ++ +T + G +G
Sbjct: 90 VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140
Query: 597 ISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTPF- 755
+SN+ ++ I +G P+ Q N +Q ELF R + AY P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLA 200
Query: 756 GSLFPSK 776
G L K
Sbjct: 201 GGLLTGK 207
>BT007347-1|AAP36011.1| 330|Homo sapiens aldo-keto reductase family
7, member A2 (aflatoxin aldehyde reductase) protein.
Length = 330
Score = 35.1 bits (77), Expect = 0.34
Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 10/187 (5%)
Frame = +3
Query: 246 AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 416
AV LE G+T +DTA+ Y G + + L G R I W+ + +
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89
Query: 417 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 596
V L SL+ L VDL+ +H P ++ T ++ +T + G +G
Sbjct: 90 VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140
Query: 597 ISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTPF- 755
+SN+ ++ I +G P+ Q N +Q ELF R + AY P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLA 200
Query: 756 GSLFPSK 776
G L K
Sbjct: 201 GGLLTGK 207
>BC013996-1|AAH13996.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 35.1 bits (77), Expect = 0.34
Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 10/187 (5%)
Frame = +3
Query: 246 AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 416
AV LE G+T +DTA+ Y G + + L G R I W+ + +
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89
Query: 417 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 596
V L SL+ L VDL+ +H P ++ T ++ +T + G +G
Sbjct: 90 VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140
Query: 597 ISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTPF- 755
+SN+ ++ I +G P+ Q N +Q ELF R + AY P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLA 200
Query: 756 GSLFPSK 776
G L K
Sbjct: 201 GGLLTGK 207
>BC012171-1|AAH12171.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 35.1 bits (77), Expect = 0.34
Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 10/187 (5%)
Frame = +3
Query: 246 AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 416
AV LE G+T +DTA+ Y G + + L G R I W+ + +
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89
Query: 417 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 596
V L SL+ L VDL+ +H P ++ T ++ +T + G +G
Sbjct: 90 VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140
Query: 597 ISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTPF- 755
+SN+ ++ I +G P+ Q N +Q ELF R + AY P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLA 200
Query: 756 GSLFPSK 776
G L K
Sbjct: 201 GGLLTGK 207
>BC011586-1|AAH11586.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 35.1 bits (77), Expect = 0.34
Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 10/187 (5%)
Frame = +3
Query: 246 AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 416
AV LE G+T +DTA+ Y G + + L G R I W+ + +
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89
Query: 417 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 596
V L SL+ L VDL+ +H P ++ T ++ +T + G +G
Sbjct: 90 VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140
Query: 597 ISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTPF- 755
+SN+ ++ I +G P+ Q N +Q ELF R + AY P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLA 200
Query: 756 GSLFPSK 776
G L K
Sbjct: 201 GGLLTGK 207
>BC010852-1|AAH10852.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 35.1 bits (77), Expect = 0.34
Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 10/187 (5%)
Frame = +3
Query: 246 AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 416
AV LE G+T +DTA+ Y G + + L G R I W+ + +
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89
Query: 417 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 596
V L SL+ L VDL+ +H P ++ T ++ +T + G +G
Sbjct: 90 VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140
Query: 597 ISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTPF- 755
+SN+ ++ I +G P+ Q N +Q ELF R + AY P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLA 200
Query: 756 GSLFPSK 776
G L K
Sbjct: 201 GGLLTGK 207
>BC007352-1|AAH07352.2| 358|Homo sapiens AKR7A2 protein protein.
Length = 358
Score = 35.1 bits (77), Expect = 0.34
Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 10/187 (5%)
Frame = +3
Query: 246 AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 416
AV LE G+T +DTA+ Y G + + L G R I W+ + +
Sbjct: 58 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 117
Query: 417 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 596
V L SL+ L VDL+ +H P ++ T ++ +T + G +G
Sbjct: 118 VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 168
Query: 597 ISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTPF- 755
+SN+ ++ I +G P+ Q N +Q ELF R + AY P
Sbjct: 169 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLA 228
Query: 756 GSLFPSK 776
G L K
Sbjct: 229 GGLLTGK 235
>BC004111-1|AAH04111.3| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 35.1 bits (77), Expect = 0.34
Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 10/187 (5%)
Frame = +3
Query: 246 AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 416
AV LE G+T +DTA+ Y G + + L G R I W+ + +
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89
Query: 417 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 596
V L SL+ L VDL+ +H P ++ T ++ +T + G +G
Sbjct: 90 VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140
Query: 597 ISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTPF- 755
+SN+ ++ I +G P+ Q N +Q ELF R + AY P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLA 200
Query: 756 GSLFPSK 776
G L K
Sbjct: 201 GGLLTGK 207
>AL035413-8|CAB72321.1| 330|Homo sapiens aldo-keto reductase family
7, member A2 (aflatoxin aldehyde reductase) protein.
Length = 330
Score = 35.1 bits (77), Expect = 0.34
Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 10/187 (5%)
Frame = +3
Query: 246 AVIYALEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYH-EREQ 416
AV LE G+T +DTA+ Y G + + L G R I W+ + +
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 89
Query: 417 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 596
V L SL+ L VDL+ +H P ++ T ++ +T + G +G
Sbjct: 90 VRSQLETSLKRLQCPQVDLFYLHAP----DHGTPVE-----ETLHACQRLHQEGKFVELG 140
Query: 597 ISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAYTPF- 755
+SN+ ++ I +G P+ Q N +Q ELF R + AY P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLA 200
Query: 756 GSLFPSK 776
G L K
Sbjct: 201 GGLLTGK 207
>BC075018-1|AAH75018.1| 599|Homo sapiens DEAQ box polypeptide 1
(RNA-dependent ATPase) protein.
Length = 599
Score = 31.9 bits (69), Expect = 3.2
Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 8/96 (8%)
Frame = +3
Query: 558 IDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVV 737
+DA+K+ +T + +F+ IQ +IDSGLE S + Q C+ +
Sbjct: 197 MDARKVVVTHWLADFSFSLPSIQHVIDSGLELRSVYNPRIRAEFQVLRPISKCQAEARRL 256
Query: 738 MAY-TPFGS---LFPSK----AQPXAPPPRIDDERL 821
A P GS L+P P P PR+ +E L
Sbjct: 257 RARGFPPGSCLCLYPKSFLELEAPPLPQPRVCEENL 292
>AK074337-1|BAB85056.1| 599|Homo sapiens protein ( Homo sapiens
cDNA FLJ23757 fis, clone HEP17946, highly similar to Mus
musculus DEAQ RNA-dependent ATPase DQX1 mRNA. ).
Length = 599
Score = 31.9 bits (69), Expect = 3.2
Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 8/96 (8%)
Frame = +3
Query: 558 IDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLNLQQPELFKFCRENDIVV 737
+DA+K+ +T + +F+ IQ +IDSGLE S + Q C+ +
Sbjct: 197 MDARKVVVTHWLADFSFSLPSIQHVIDSGLELRSVYNPRIRAEFQVLRPISKCQAEARRL 256
Query: 738 MAY-TPFGS---LFPSK----AQPXAPPPRIDDERL 821
A P GS L+P P P PR+ +E L
Sbjct: 257 RARGFPPGSCLCLYPKSFLELEAPPLPQPRVCEENL 292
>M64590-1|AAA36463.1| 1020|Homo sapiens glycine decarboxylase
protein.
Length = 1020
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/37 (37%), Positives = 24/37 (64%)
Frame = +3
Query: 357 KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 467
KR S F+T +++NSYH ++ ++K LEN ++ V
Sbjct: 514 KRTSPFLTHQVFNSYHSETNIVRYMKK-LENKDISLV 549
>M63635-1|AAA36478.1| 1020|Homo sapiens glycine decarboxylase
protein.
Length = 1020
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/37 (37%), Positives = 24/37 (64%)
Frame = +3
Query: 357 KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 467
KR S F+T +++NSYH ++ ++K LEN ++ V
Sbjct: 514 KRTSPFLTHQVFNSYHSETNIVRYMKK-LENKDISLV 549
>D90239-1|BAA14286.1| 1020|Homo sapiens glycine decarboxylase
precursor protein.
Length = 1020
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/37 (37%), Positives = 24/37 (64%)
Frame = +3
Query: 357 KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 467
KR S F+T +++NSYH ++ ++K LEN ++ V
Sbjct: 514 KRTSPFLTHQVFNSYHSETNIVRYMKK-LENKDISLV 549
>BC111995-1|AAI11996.1| 1020|Homo sapiens glycine dehydrogenase
(decarboxylating) protein.
Length = 1020
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/37 (37%), Positives = 24/37 (64%)
Frame = +3
Query: 357 KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 467
KR S F+T +++NSYH ++ ++K LEN ++ V
Sbjct: 514 KRTSPFLTHQVFNSYHSETNIVRYMKK-LENKDISLV 549
>BC111993-1|AAI11994.1| 1020|Homo sapiens glycine dehydrogenase
(decarboxylating) protein.
Length = 1020
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/37 (37%), Positives = 24/37 (64%)
Frame = +3
Query: 357 KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 467
KR S F+T +++NSYH ++ ++K LEN ++ V
Sbjct: 514 KRTSPFLTHQVFNSYHSETNIVRYMKK-LENKDISLV 549
>AL353718-2|CAH74116.1| 1036|Homo sapiens glycine dehydrogenase
(decarboxylating) protein.
Length = 1036
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/37 (37%), Positives = 24/37 (64%)
Frame = +3
Query: 357 KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 467
KR S F+T +++NSYH ++ ++K LEN ++ V
Sbjct: 514 KRTSPFLTHQVFNSYHSETNIVRYMKK-LENKDISLV 549
>AL162411-3|CAH69992.1| 1036|Homo sapiens glycine dehydrogenase
(decarboxylating) protein.
Length = 1036
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/37 (37%), Positives = 24/37 (64%)
Frame = +3
Query: 357 KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 467
KR S F+T +++NSYH ++ ++K LEN ++ V
Sbjct: 514 KRTSPFLTHQVFNSYHSETNIVRYMKK-LENKDISLV 549
>AF246134-1|AAK28443.2| 331|Homo sapiens glycine decarboxylase
P-protein protein.
Length = 331
Score = 31.1 bits (67), Expect = 5.5
Identities = 14/37 (37%), Positives = 24/37 (64%)
Frame = +3
Query: 357 KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 467
KR S F+T +++NSYH ++ ++K LEN ++ V
Sbjct: 276 KRTSPFLTHQVFNSYHSETNIVRYMKK-LENKDISLV 311
>BC042420-1|AAH42420.2| 331|Homo sapiens aldo-keto reductase family
7, member A3 (aflatoxin aldehyde reductase) protein.
Length = 331
Score = 30.7 bits (66), Expect = 7.3
Identities = 49/191 (25%), Positives = 78/191 (40%), Gaps = 11/191 (5%)
Frame = +3
Query: 237 TEQAVIYA-LEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFI-TTKLWNSYH 404
T AV A LE G+T IDTA+ Y G + + L + R I L+ +
Sbjct: 27 TSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSL 86
Query: 405 EREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLT 584
+ + + L SL+ L VDL+ +H P ++ T ++ +T R + G
Sbjct: 87 KPDSLRFQLETSLKRLQCPRVDLFYLHMP----DHSTPVE-----ETLRACHQLHQEGKF 137
Query: 585 KSIGISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAY 746
+G+SN+ ++ I +G P+ Q N +Q ELF R + A+
Sbjct: 138 MELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAF 197
Query: 747 TPF-GSLFPSK 776
P G L K
Sbjct: 198 NPLAGGLLTGK 208
>BC031562-1|AAH31562.1| 331|Homo sapiens aldo-keto reductase family
7, member A3 (aflatoxin aldehyde reductase) protein.
Length = 331
Score = 30.7 bits (66), Expect = 7.3
Identities = 49/191 (25%), Positives = 78/191 (40%), Gaps = 11/191 (5%)
Frame = +3
Query: 237 TEQAVIYA-LEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFI-TTKLWNSYH 404
T AV A LE G+T IDTA+ Y G + + L + R I L+ +
Sbjct: 27 TSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSL 86
Query: 405 EREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLT 584
+ + + L SL+ L VDL+ +H P ++ T ++ +T R + G
Sbjct: 87 KPDSLRFQLETSLKRLQCPRVDLFYLHMP----DHSTPVE-----ETLRACHQLHQEGKF 137
Query: 585 KSIGISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAY 746
+G+SN+ ++ I +G P+ Q N +Q ELF R + A+
Sbjct: 138 MELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAF 197
Query: 747 TPF-GSLFPSK 776
P G L K
Sbjct: 198 NPLAGGLLTGK 208
>BC029488-1|AAH29488.1| 294|Homo sapiens sperm acrosome associated
1 protein.
Length = 294
Score = 30.7 bits (66), Expect = 7.3
Identities = 17/56 (30%), Positives = 25/56 (44%)
Frame = +3
Query: 93 CLSALCFTSADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYA 260
C + L T L++ LQ + G N+ L H +G+ ND+E A YA
Sbjct: 8 CSAGLLMTVGWLLLAGLQSARGTNVTAAVQDAGLAHEGEGEEETENNDSETAENYA 63
>AL136096-1|CAI19915.1| 294|Homo sapiens sperm acrosome associated
1 protein.
Length = 294
Score = 30.7 bits (66), Expect = 7.3
Identities = 17/56 (30%), Positives = 25/56 (44%)
Frame = +3
Query: 93 CLSALCFTSADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYA 260
C + L T L++ LQ + G N+ L H +G+ ND+E A YA
Sbjct: 8 CSAGLLMTVGWLLLAGLQSARGTNVTAAVQDAGLAHEGEGEEETENNDSETAENYA 63
>AJ271799-1|CAC81076.1| 331|Homo sapiens aflatoxin B1 aldehyde
reductase 2 protein.
Length = 331
Score = 30.7 bits (66), Expect = 7.3
Identities = 49/191 (25%), Positives = 78/191 (40%), Gaps = 11/191 (5%)
Frame = +3
Query: 237 TEQAVIYA-LEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFI-TTKLWNSYH 404
T AV A LE G+T IDTA+ Y G + + L + R I L+ +
Sbjct: 27 TSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSL 86
Query: 405 EREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLT 584
+ + + L SL+ L VDL+ +H P ++ T ++ +T R + G
Sbjct: 87 KPDSLRFQLETSLKRLQCPRVDLFYLHMP----DHSTPVE-----ETLRACHQLHQEGKF 137
Query: 585 KSIGISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAY 746
+G+SN+ ++ I +G P+ Q N +Q ELF R + A+
Sbjct: 138 MELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAF 197
Query: 747 TPF-GSLFPSK 776
P G L K
Sbjct: 198 NPLAGGLLTGK 208
>AF203447-1|AAG31422.1| 294|Homo sapiens sperm acrosome membrane
protein SAMP32 protein.
Length = 294
Score = 30.7 bits (66), Expect = 7.3
Identities = 17/56 (30%), Positives = 25/56 (44%)
Frame = +3
Query: 93 CLSALCFTSADLIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYA 260
C + L T L++ LQ + G N+ L H +G+ ND+E A YA
Sbjct: 8 CSAGLLMTVGWLLLAGLQSARGTNVTAAVQDAGLAHEGEGEEETENNDSETAENYA 63
>AF040639-1|AAD02195.1| 331|Homo sapiens aflatoxin B1-aldehyde
reductase protein.
Length = 331
Score = 30.7 bits (66), Expect = 7.3
Identities = 49/191 (25%), Positives = 78/191 (40%), Gaps = 11/191 (5%)
Frame = +3
Query: 237 TEQAVIYA-LEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFI-TTKLWNSYH 404
T AV A LE G+T IDTA+ Y G + + L + R I L+ +
Sbjct: 27 TSAAVTRAFLERGHTEIDTAFVYSDGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSL 86
Query: 405 EREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLT 584
+ + + L SL+ L VDL+ +H P ++ T ++ +T R + G
Sbjct: 87 KPDSLRFQLETSLKRLQCPRVDLFYLHMP----DHSTPVE-----ETLRACHQLHQEGKF 137
Query: 585 KSIGISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAY 746
+G+SN+ ++ I +G P+ Q N +Q ELF R + A+
Sbjct: 138 MELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAF 197
Query: 747 TPF-GSLFPSK 776
P G L K
Sbjct: 198 NPLAGGLLTGK 208
>BC025709-1|AAH25709.1| 331|Homo sapiens aldo-keto reductase family
7, member A3 (aflatoxin aldehyde reductase) protein.
Length = 331
Score = 30.3 bits (65), Expect = 9.7
Identities = 49/191 (25%), Positives = 78/191 (40%), Gaps = 11/191 (5%)
Frame = +3
Query: 237 TEQAVIYA-LEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFI-TTKLWNSYH 404
T AV A LE G+T IDTA+ Y G + + L + R I L+ +
Sbjct: 27 TSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSL 86
Query: 405 EREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLT 584
+ + + L SL+ L VDL+ +H P ++ T ++ +T R + G
Sbjct: 87 KPDSLRFQLETSLKRLQCPRVDLFYLHMP----DHSTPVE-----ETLRACHQLHQEGKF 137
Query: 585 KSIGISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAY 746
+G+SN+ ++ I +G P+ Q N +Q ELF R + A+
Sbjct: 138 VELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAF 197
Query: 747 TPF-GSLFPSK 776
P G L K
Sbjct: 198 NPLAGGLLTGK 208
>AL035413-11|CAI22232.1| 331|Homo sapiens aldo-keto reductase
family 7, member A3 (aflatoxin aldehyde reductase)
protein.
Length = 331
Score = 30.3 bits (65), Expect = 9.7
Identities = 49/191 (25%), Positives = 78/191 (40%), Gaps = 11/191 (5%)
Frame = +3
Query: 237 TEQAVIYA-LEAGYTHIDTAYKY--GIEDQVGRALTKKFSEGLKRESIFI-TTKLWNSYH 404
T AV A LE G+T IDTA+ Y G + + L + R I L+ +
Sbjct: 27 TSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSL 86
Query: 405 EREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLT 584
+ + + L SL+ L VDL+ +H P ++ T ++ +T R + G
Sbjct: 87 KPDSLRFQLETSLKRLQCPRVDLFYLHMP----DHSTPVE-----ETLRACHQLHQEGKF 137
Query: 585 KSIGISNFNQEQIQRII----DSGLEKPSALQIELNLNLQQ--PELFKFCRENDIVVMAY 746
+G+SN+ ++ I +G P+ Q N +Q ELF R + A+
Sbjct: 138 VELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAF 197
Query: 747 TPF-GSLFPSK 776
P G L K
Sbjct: 198 NPLAGGLLTGK 208
>AK092420-1|BAC03884.1| 357|Homo sapiens protein ( Homo sapiens
cDNA FLJ35101 fis, clone PLACE6006418, weakly similar to
PUTATIVE PRE-MRNA SPLICING FACTOR ATP-DEPENDENT RNA
HELICASE. ).
Length = 357
Score = 30.3 bits (65), Expect = 9.7
Identities = 15/40 (37%), Positives = 25/40 (62%)
Frame = +3
Query: 558 IDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 677
+DA+K+ +T + +F+ IQ +IDSGLE S + E+
Sbjct: 315 MDARKVVVTHWLADFSFSLPSIQHVIDSGLELRSVSEREI 354
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 138,575,426
Number of Sequences: 237096
Number of extensions: 3252659
Number of successful extensions: 12555
Number of sequences better than 10.0: 140
Number of HSP's better than 10.0 without gapping: 11851
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 12270
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11270645666
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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