Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP14_F_G23
(888 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X88562-1|CAA61252.1| 551|Homo sapiens cystathionine beta-syntha... 159 9e-39
X82166-1|CAA57656.1| 551|Homo sapiens cystathionine beta-syntha... 159 9e-39
L19501-1|AAA19874.1| 551|Homo sapiens cystathionine beta-syntha... 159 9e-39
L14577-1|AAA98524.1| 551|Homo sapiens cystathionine beta-syntha... 159 9e-39
BT007154-1|AAP35818.1| 551|Homo sapiens cystathionine-beta-synt... 159 9e-39
BC011381-1|AAH11381.1| 551|Homo sapiens CBS protein protein. 159 9e-39
BC010242-1|AAH10242.1| 551|Homo sapiens CBS protein protein. 159 9e-39
BC007257-1|AAH07257.1| 551|Homo sapiens CBS protein protein. 159 9e-39
AF042836-2|AAC64683.1| 551|Homo sapiens cystathionine beta-synt... 159 9e-39
AF042836-1|AAC64684.1| 565|Homo sapiens cystathionine beta-synt... 159 9e-39
BC000440-1|AAH00440.1| 551|Homo sapiens CBS protein protein. 157 4e-38
AL137314-1|CAB70691.1| 475|Homo sapiens hypothetical protein pr... 152 2e-36
BC091479-1|AAH91479.1| 329|Homo sapiens SDSL protein protein. 35 0.34
BC009849-1|AAH09849.1| 329|Homo sapiens serine dehydratase-like... 35 0.34
AF134473-1|AAP97250.1| 329|Homo sapiens serine dehydratase-2 pr... 35 0.34
>X88562-1|CAA61252.1| 551|Homo sapiens cystathionine beta-synthase
protein.
Length = 551
Score = 159 bits (387), Expect = 9e-39
Identities = 87/174 (50%), Positives = 105/174 (60%)
Frame = +3
Query: 366 DMPHIVRALDRNQKVHSDILNVIGNTPLVKLSKLPKDEGLKCEMYAKCEFLNPGGSVKDR 545
+ PH A ++ K+ DIL IG+TP+V+++K+ K GLKCE+ AKCEF N GGSVKDR
Sbjct: 62 ESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDR 121
Query: 546 IAYRMFLDAEXKGILKPGKSVIVXPTSGNTGIGLALAAAVRGYRCIIXLPXKMSDEKVNT 725
I+ RM DAE G LKPG I+ PTSGNTGIGLALAAAVRGYRCII +P KMS EKV+
Sbjct: 122 ISLRMIEDAERDGTLKPG-DTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV 180
Query: 726 LGXIGC*NNPAXQLKLPXXHPXAHHGLRIXSLNXYRPXLSPXXYXNPXQPLAHY 887
L +G P +H G+ N Y N PLAHY
Sbjct: 181 LRALGA-EIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHY 233
>X82166-1|CAA57656.1| 551|Homo sapiens cystathionine beta-synthase
protein.
Length = 551
Score = 159 bits (387), Expect = 9e-39
Identities = 87/174 (50%), Positives = 105/174 (60%)
Frame = +3
Query: 366 DMPHIVRALDRNQKVHSDILNVIGNTPLVKLSKLPKDEGLKCEMYAKCEFLNPGGSVKDR 545
+ PH A ++ K+ DIL IG+TP+V+++K+ K GLKCE+ AKCEF N GGSVKDR
Sbjct: 62 ESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDR 121
Query: 546 IAYRMFLDAEXKGILKPGKSVIVXPTSGNTGIGLALAAAVRGYRCIIXLPXKMSDEKVNT 725
I+ RM DAE G LKPG I+ PTSGNTGIGLALAAAVRGYRCII +P KMS EKV+
Sbjct: 122 ISLRMIEDAERDGTLKPG-DTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV 180
Query: 726 LGXIGC*NNPAXQLKLPXXHPXAHHGLRIXSLNXYRPXLSPXXYXNPXQPLAHY 887
L +G P +H G+ N Y N PLAHY
Sbjct: 181 LRALGA-EIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHY 233
>L19501-1|AAA19874.1| 551|Homo sapiens cystathionine beta-synthase
protein.
Length = 551
Score = 159 bits (387), Expect = 9e-39
Identities = 87/174 (50%), Positives = 105/174 (60%)
Frame = +3
Query: 366 DMPHIVRALDRNQKVHSDILNVIGNTPLVKLSKLPKDEGLKCEMYAKCEFLNPGGSVKDR 545
+ PH A ++ K+ DIL IG+TP+V+++K+ K GLKCE+ AKCEF N GGSVKDR
Sbjct: 62 ESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDR 121
Query: 546 IAYRMFLDAEXKGILKPGKSVIVXPTSGNTGIGLALAAAVRGYRCIIXLPXKMSDEKVNT 725
I+ RM DAE G LKPG I+ PTSGNTGIGLALAAAVRGYRCII +P KMS EKV+
Sbjct: 122 ISLRMIEDAERDGTLKPG-DTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV 180
Query: 726 LGXIGC*NNPAXQLKLPXXHPXAHHGLRIXSLNXYRPXLSPXXYXNPXQPLAHY 887
L +G P +H G+ N Y N PLAHY
Sbjct: 181 LRALGA-EIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHY 233
>L14577-1|AAA98524.1| 551|Homo sapiens cystathionine beta-synthase
protein.
Length = 551
Score = 159 bits (387), Expect = 9e-39
Identities = 87/174 (50%), Positives = 105/174 (60%)
Frame = +3
Query: 366 DMPHIVRALDRNQKVHSDILNVIGNTPLVKLSKLPKDEGLKCEMYAKCEFLNPGGSVKDR 545
+ PH A ++ K+ DIL IG+TP+V+++K+ K GLKCE+ AKCEF N GGSVKDR
Sbjct: 62 ESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDR 121
Query: 546 IAYRMFLDAEXKGILKPGKSVIVXPTSGNTGIGLALAAAVRGYRCIIXLPXKMSDEKVNT 725
I+ RM DAE G LKPG I+ PTSGNTGIGLALAAAVRGYRCII +P KMS EKV+
Sbjct: 122 ISLRMIEDAERDGTLKPG-DTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV 180
Query: 726 LGXIGC*NNPAXQLKLPXXHPXAHHGLRIXSLNXYRPXLSPXXYXNPXQPLAHY 887
L +G P +H G+ N Y N PLAHY
Sbjct: 181 LRALGA-EIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHY 233
>BT007154-1|AAP35818.1| 551|Homo sapiens
cystathionine-beta-synthase protein.
Length = 551
Score = 159 bits (387), Expect = 9e-39
Identities = 87/174 (50%), Positives = 105/174 (60%)
Frame = +3
Query: 366 DMPHIVRALDRNQKVHSDILNVIGNTPLVKLSKLPKDEGLKCEMYAKCEFLNPGGSVKDR 545
+ PH A ++ K+ DIL IG+TP+V+++K+ K GLKCE+ AKCEF N GGSVKDR
Sbjct: 62 ESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDR 121
Query: 546 IAYRMFLDAEXKGILKPGKSVIVXPTSGNTGIGLALAAAVRGYRCIIXLPXKMSDEKVNT 725
I+ RM DAE G LKPG I+ PTSGNTGIGLALAAAVRGYRCII +P KMS EKV+
Sbjct: 122 ISLRMIEDAERDGTLKPG-DTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV 180
Query: 726 LGXIGC*NNPAXQLKLPXXHPXAHHGLRIXSLNXYRPXLSPXXYXNPXQPLAHY 887
L +G P +H G+ N Y N PLAHY
Sbjct: 181 LRALGA-EIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHY 233
>BC011381-1|AAH11381.1| 551|Homo sapiens CBS protein protein.
Length = 551
Score = 159 bits (387), Expect = 9e-39
Identities = 87/174 (50%), Positives = 105/174 (60%)
Frame = +3
Query: 366 DMPHIVRALDRNQKVHSDILNVIGNTPLVKLSKLPKDEGLKCEMYAKCEFLNPGGSVKDR 545
+ PH A ++ K+ DIL IG+TP+V+++K+ K GLKCE+ AKCEF N GGSVKDR
Sbjct: 62 ESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDR 121
Query: 546 IAYRMFLDAEXKGILKPGKSVIVXPTSGNTGIGLALAAAVRGYRCIIXLPXKMSDEKVNT 725
I+ RM DAE G LKPG I+ PTSGNTGIGLALAAAVRGYRCII +P KMS EKV+
Sbjct: 122 ISLRMIEDAERDGTLKPG-DTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV 180
Query: 726 LGXIGC*NNPAXQLKLPXXHPXAHHGLRIXSLNXYRPXLSPXXYXNPXQPLAHY 887
L +G P +H G+ N Y N PLAHY
Sbjct: 181 LRALGA-EIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHY 233
>BC010242-1|AAH10242.1| 551|Homo sapiens CBS protein protein.
Length = 551
Score = 159 bits (387), Expect = 9e-39
Identities = 87/174 (50%), Positives = 105/174 (60%)
Frame = +3
Query: 366 DMPHIVRALDRNQKVHSDILNVIGNTPLVKLSKLPKDEGLKCEMYAKCEFLNPGGSVKDR 545
+ PH A ++ K+ DIL IG+TP+V+++K+ K GLKCE+ AKCEF N GGSVKDR
Sbjct: 62 ESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDR 121
Query: 546 IAYRMFLDAEXKGILKPGKSVIVXPTSGNTGIGLALAAAVRGYRCIIXLPXKMSDEKVNT 725
I+ RM DAE G LKPG I+ PTSGNTGIGLALAAAVRGYRCII +P KMS EKV+
Sbjct: 122 ISLRMIEDAERDGTLKPG-DTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV 180
Query: 726 LGXIGC*NNPAXQLKLPXXHPXAHHGLRIXSLNXYRPXLSPXXYXNPXQPLAHY 887
L +G P +H G+ N Y N PLAHY
Sbjct: 181 LRALGA-EIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHY 233
>BC007257-1|AAH07257.1| 551|Homo sapiens CBS protein protein.
Length = 551
Score = 159 bits (387), Expect = 9e-39
Identities = 87/174 (50%), Positives = 105/174 (60%)
Frame = +3
Query: 366 DMPHIVRALDRNQKVHSDILNVIGNTPLVKLSKLPKDEGLKCEMYAKCEFLNPGGSVKDR 545
+ PH A ++ K+ DIL IG+TP+V+++K+ K GLKCE+ AKCEF N GGSVKDR
Sbjct: 62 ESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDR 121
Query: 546 IAYRMFLDAEXKGILKPGKSVIVXPTSGNTGIGLALAAAVRGYRCIIXLPXKMSDEKVNT 725
I+ RM DAE G LKPG I+ PTSGNTGIGLALAAAVRGYRCII +P KMS EKV+
Sbjct: 122 ISLRMIEDAERDGTLKPG-DTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV 180
Query: 726 LGXIGC*NNPAXQLKLPXXHPXAHHGLRIXSLNXYRPXLSPXXYXNPXQPLAHY 887
L +G P +H G+ N Y N PLAHY
Sbjct: 181 LRALGA-EIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHY 233
>AF042836-2|AAC64683.1| 551|Homo sapiens cystathionine
beta-synthase major isoform protein.
Length = 551
Score = 159 bits (387), Expect = 9e-39
Identities = 87/174 (50%), Positives = 105/174 (60%)
Frame = +3
Query: 366 DMPHIVRALDRNQKVHSDILNVIGNTPLVKLSKLPKDEGLKCEMYAKCEFLNPGGSVKDR 545
+ PH A ++ K+ DIL IG+TP+V+++K+ K GLKCE+ AKCEF N GGSVKDR
Sbjct: 62 ESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDR 121
Query: 546 IAYRMFLDAEXKGILKPGKSVIVXPTSGNTGIGLALAAAVRGYRCIIXLPXKMSDEKVNT 725
I+ RM DAE G LKPG I+ PTSGNTGIGLALAAAVRGYRCII +P KMS EKV+
Sbjct: 122 ISLRMIEDAERDGTLKPG-DTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV 180
Query: 726 LGXIGC*NNPAXQLKLPXXHPXAHHGLRIXSLNXYRPXLSPXXYXNPXQPLAHY 887
L +G P +H G+ N Y N PLAHY
Sbjct: 181 LRALGA-EIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHY 233
>AF042836-1|AAC64684.1| 565|Homo sapiens cystathionine
beta-synthase minor isoform protein.
Length = 565
Score = 159 bits (387), Expect = 9e-39
Identities = 87/174 (50%), Positives = 105/174 (60%)
Frame = +3
Query: 366 DMPHIVRALDRNQKVHSDILNVIGNTPLVKLSKLPKDEGLKCEMYAKCEFLNPGGSVKDR 545
+ PH A ++ K+ DIL IG+TP+V+++K+ K GLKCE+ AKCEF N GGSVKDR
Sbjct: 62 ESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDR 121
Query: 546 IAYRMFLDAEXKGILKPGKSVIVXPTSGNTGIGLALAAAVRGYRCIIXLPXKMSDEKVNT 725
I+ RM DAE G LKPG I+ PTSGNTGIGLALAAAVRGYRCII +P KMS EKV+
Sbjct: 122 ISLRMIEDAERDGTLKPG-DTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV 180
Query: 726 LGXIGC*NNPAXQLKLPXXHPXAHHGLRIXSLNXYRPXLSPXXYXNPXQPLAHY 887
L +G P +H G+ N Y N PLAHY
Sbjct: 181 LRALGA-EIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHY 233
>BC000440-1|AAH00440.1| 551|Homo sapiens CBS protein protein.
Length = 551
Score = 157 bits (382), Expect = 4e-38
Identities = 86/174 (49%), Positives = 104/174 (59%)
Frame = +3
Query: 366 DMPHIVRALDRNQKVHSDILNVIGNTPLVKLSKLPKDEGLKCEMYAKCEFLNPGGSVKDR 545
+ PH ++ K+ DIL IG+TP+V+++K+ K GLKCE+ AKCEF N GGSVKDR
Sbjct: 62 ESPHHHTPPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDR 121
Query: 546 IAYRMFLDAEXKGILKPGKSVIVXPTSGNTGIGLALAAAVRGYRCIIXLPXKMSDEKVNT 725
I+ RM DAE G LKPG I+ PTSGNTGIGLALAAAVRGYRCII +P KMS EKV+
Sbjct: 122 ISLRMIEDAERDGTLKPG-DTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV 180
Query: 726 LGXIGC*NNPAXQLKLPXXHPXAHHGLRIXSLNXYRPXLSPXXYXNPXQPLAHY 887
L +G P +H G+ N Y N PLAHY
Sbjct: 181 LRALGA-EIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHY 233
>AL137314-1|CAB70691.1| 475|Homo sapiens hypothetical protein
protein.
Length = 475
Score = 152 bits (368), Expect = 2e-36
Identities = 82/157 (52%), Positives = 96/157 (61%)
Frame = +3
Query: 417 DILNVIGNTPLVKLSKLPKDEGLKCEMYAKCEFLNPGGSVKDRIAYRMFLDAEXKGILKP 596
DIL IG+TP+V+++K+ K GLKCE+ AKCEF N GGSVKDRI+ RM DAE G LKP
Sbjct: 3 DILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKP 62
Query: 597 GKSVIVXPTSGNTGIGLALAAAVRGYRCIIXLPXKMSDEKVNTLGXIGC*NNPAXQLKLP 776
G I+ PTSGNTGIGLALAAAVRGYRCII +P KMS EKV+ L +G
Sbjct: 63 G-DTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGA-EIVRTPTNAR 120
Query: 777 XXHPXAHHGLRIXSLNXYRPXLSPXXYXNPXQPLAHY 887
P +H G+ N Y N PL HY
Sbjct: 121 FDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLPHY 157
>BC091479-1|AAH91479.1| 329|Homo sapiens SDSL protein protein.
Length = 329
Score = 35.1 bits (77), Expect = 0.34
Identities = 30/96 (31%), Positives = 43/96 (44%)
Frame = +3
Query: 441 TPLVKLSKLPKDEGLKCEMYAKCEFLNPGGSVKDRIAYRMFLDAEXKGILKPGKSVIVXP 620
TPL++ L + G+ ++ KCE + P GS K R + + + K G +V
Sbjct: 18 TPLLESWALSQVAGMP--VFLKCENVQPSGSFKIR-----GIGHFCQEMAKKGCRHLVCS 70
Query: 621 TSGNTGIGLALAAAVRGYRCIIXLPXKMSDEKVNTL 728
+ GN GI A AA G I LP S + V L
Sbjct: 71 SGGNAGIAAAYAARKLGIPATIVLPESTSLQVVQRL 106
>BC009849-1|AAH09849.1| 329|Homo sapiens serine dehydratase-like
protein.
Length = 329
Score = 35.1 bits (77), Expect = 0.34
Identities = 30/96 (31%), Positives = 43/96 (44%)
Frame = +3
Query: 441 TPLVKLSKLPKDEGLKCEMYAKCEFLNPGGSVKDRIAYRMFLDAEXKGILKPGKSVIVXP 620
TPL++ L + G+ ++ KCE + P GS K R + + + K G +V
Sbjct: 18 TPLLESWALSQVAGMP--VFLKCENVQPSGSFKIR-----GIGHFCQEMAKKGCRHLVCS 70
Query: 621 TSGNTGIGLALAAAVRGYRCIIXLPXKMSDEKVNTL 728
+ GN GI A AA G I LP S + V L
Sbjct: 71 SGGNAGIAAAYAARKLGIPATIVLPESTSLQVVQRL 106
>AF134473-1|AAP97250.1| 329|Homo sapiens serine dehydratase-2
protein.
Length = 329
Score = 35.1 bits (77), Expect = 0.34
Identities = 30/96 (31%), Positives = 43/96 (44%)
Frame = +3
Query: 441 TPLVKLSKLPKDEGLKCEMYAKCEFLNPGGSVKDRIAYRMFLDAEXKGILKPGKSVIVXP 620
TPL++ L + G+ ++ KCE + P GS K R + + + K G +V
Sbjct: 18 TPLLESWALSQVAGMP--VFLKCENVQPSGSFKIR-----GIGHFCQEMAKKGCRHLVCS 70
Query: 621 TSGNTGIGLALAAAVRGYRCIIXLPXKMSDEKVNTL 728
+ GN GI A AA G I LP S + V L
Sbjct: 71 SGGNAGIAAAYAARKLGIPATIVLPESTSLQVVQRL 106
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 117,206,221
Number of Sequences: 237096
Number of extensions: 2311213
Number of successful extensions: 3973
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 3745
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3958
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11381686510
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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