Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP12_F_N05
(915 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein. 138 3e-32
CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein. 138 3e-32
BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein pr... 138 3e-32
BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenas... 138 3e-32
BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein. 138 3e-32
AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitr... 138 3e-32
AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitra... 138 3e-32
AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein. 138 3e-32
DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenas... 136 1e-31
CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein. 135 2e-31
X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase... 127 6e-29
BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenas... 127 6e-29
BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenas... 127 6e-29
AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenas... 127 6e-29
U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase ... 125 3e-28
U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic NADP-d... 93 1e-18
>CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 138 bits (333), Expect = 3e-32
Identities = 63/85 (74%), Positives = 73/85 (85%)
Frame = +1
Query: 190 LSKKS*FFLFLDIXLHVYDLGMXNRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVE 369
L K+ F ++++ LH YDLG+ NRD T+DQVT D AEAIKK+NVG+KCATITPDEKRVE
Sbjct: 25 LIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVE 84
Query: 370 EFXLKKMWKSPNGTIRNILGGTVFR 444
EF LK+MWKSPNGTIRNILGGTVFR
Sbjct: 85 EFKLKQMWKSPNGTIRNILGGTVFR 109
Score = 93.5 bits (222), Expect = 1e-18
Identities = 48/104 (46%), Positives = 61/104 (58%), Gaps = 2/104 (1%)
Frame = +2
Query: 449 AIICKNIPRLVTGWDKPIIIGRXAHADQYKATDFVVPGAGTLXIXFKPESG-EAIKXVVX 625
AIICKNIPRLV+GW KPIIIGR A+ DQY+ATDFVVPG G + I + P G + + +V
Sbjct: 111 AIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVH 170
Query: 626 EY-QGAXVALAMFXTXXXXXXXXXXXXXXXLDXKYPLYLXTXXT 754
+ +G VA+ M+ L +PLYL T T
Sbjct: 171 NFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNT 214
Score = 39.9 bits (89), Expect = 0.013
Identities = 21/32 (65%), Positives = 26/32 (81%)
Frame = +3
Query: 120 KINGWTVVVDIHCADEMTRIIWDLIKEKLILP 215
KI+G +VV ++ DEMTRIIW+LIKEKLI P
Sbjct: 4 KISGGSVV-EMQ-GDEMTRIIWELIKEKLIFP 33
>CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 138 bits (333), Expect = 3e-32
Identities = 63/85 (74%), Positives = 73/85 (85%)
Frame = +1
Query: 190 LSKKS*FFLFLDIXLHVYDLGMXNRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVE 369
L K+ F ++++ LH YDLG+ NRD T+DQVT D AEAIKK+NVG+KCATITPDEKRVE
Sbjct: 25 LIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVE 84
Query: 370 EFXLKKMWKSPNGTIRNILGGTVFR 444
EF LK+MWKSPNGTIRNILGGTVFR
Sbjct: 85 EFKLKQMWKSPNGTIRNILGGTVFR 109
Score = 92.3 bits (219), Expect = 2e-18
Identities = 47/104 (45%), Positives = 61/104 (58%), Gaps = 2/104 (1%)
Frame = +2
Query: 449 AIICKNIPRLVTGWDKPIIIGRXAHADQYKATDFVVPGAGTLXIXFKPESG-EAIKXVVX 625
AIICKNIPRLV+GW KPIIIGR A+ DQY+ATDFVVPG G + + + P G + + +V
Sbjct: 111 AIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEMTYTPSDGTQKVTYLVH 170
Query: 626 EY-QGAXVALAMFXTXXXXXXXXXXXXXXXLDXKYPLYLXTXXT 754
+ +G VA+ M+ L +PLYL T T
Sbjct: 171 NFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNT 214
Score = 39.9 bits (89), Expect = 0.013
Identities = 21/32 (65%), Positives = 26/32 (81%)
Frame = +3
Query: 120 KINGWTVVVDIHCADEMTRIIWDLIKEKLILP 215
KI+G +VV ++ DEMTRIIW+LIKEKLI P
Sbjct: 4 KISGGSVV-EMQ-GDEMTRIIWELIKEKLIFP 33
>BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein
protein.
Length = 414
Score = 138 bits (333), Expect = 3e-32
Identities = 63/85 (74%), Positives = 73/85 (85%)
Frame = +1
Query: 190 LSKKS*FFLFLDIXLHVYDLGMXNRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVE 369
L K+ F ++++ LH YDLG+ NRD T+DQVT D AEAIKK+NVG+KCATITPDEKRVE
Sbjct: 25 LIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVE 84
Query: 370 EFXLKKMWKSPNGTIRNILGGTVFR 444
EF LK+MWKSPNGTIRNILGGTVFR
Sbjct: 85 EFKLKQMWKSPNGTIRNILGGTVFR 109
Score = 91.5 bits (217), Expect = 4e-18
Identities = 48/104 (46%), Positives = 60/104 (57%), Gaps = 2/104 (1%)
Frame = +2
Query: 449 AIICKNIPRLVTGWDKPIIIGRXAHADQYKATDFVVPGAGTLXIXFKPESG-EAIKXVVX 625
AIICKNIPRLV+GW KPIIIGR A+ DQY+ATDFVVPG G + I + P G + + +V
Sbjct: 111 AIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVH 170
Query: 626 EYQ-GAXVALAMFXTXXXXXXXXXXXXXXXLDXKYPLYLXTXXT 754
+ G VA+ M+ L +PLYL T T
Sbjct: 171 NSEGGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNT 214
Score = 39.9 bits (89), Expect = 0.013
Identities = 21/32 (65%), Positives = 26/32 (81%)
Frame = +3
Query: 120 KINGWTVVVDIHCADEMTRIIWDLIKEKLILP 215
KI+G +VV ++ DEMTRIIW+LIKEKLI P
Sbjct: 4 KISGGSVV-EMQ-GDEMTRIIWELIKEKLIFP 33
>BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenase 1
(NADP+), soluble protein.
Length = 414
Score = 138 bits (333), Expect = 3e-32
Identities = 63/85 (74%), Positives = 73/85 (85%)
Frame = +1
Query: 190 LSKKS*FFLFLDIXLHVYDLGMXNRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVE 369
L K+ F ++++ LH YDLG+ NRD T+DQVT D AEAIKK+NVG+KCATITPDEKRVE
Sbjct: 25 LIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVE 84
Query: 370 EFXLKKMWKSPNGTIRNILGGTVFR 444
EF LK+MWKSPNGTIRNILGGTVFR
Sbjct: 85 EFKLKQMWKSPNGTIRNILGGTVFR 109
Score = 93.5 bits (222), Expect = 1e-18
Identities = 48/104 (46%), Positives = 61/104 (58%), Gaps = 2/104 (1%)
Frame = +2
Query: 449 AIICKNIPRLVTGWDKPIIIGRXAHADQYKATDFVVPGAGTLXIXFKPESG-EAIKXVVX 625
AIICKNIPRLV+GW KPIIIGR A+ DQY+ATDFVVPG G + I + P G + + +V
Sbjct: 111 AIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVH 170
Query: 626 EY-QGAXVALAMFXTXXXXXXXXXXXXXXXLDXKYPLYLXTXXT 754
+ +G VA+ M+ L +PLYL T T
Sbjct: 171 NFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNT 214
Score = 39.9 bits (89), Expect = 0.013
Identities = 21/32 (65%), Positives = 26/32 (81%)
Frame = +3
Query: 120 KINGWTVVVDIHCADEMTRIIWDLIKEKLILP 215
KI+G +VV ++ DEMTRIIW+LIKEKLI P
Sbjct: 4 KISGGSVV-EMQ-GDEMTRIIWELIKEKLIFP 33
>BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein.
Length = 414
Score = 138 bits (333), Expect = 3e-32
Identities = 63/85 (74%), Positives = 73/85 (85%)
Frame = +1
Query: 190 LSKKS*FFLFLDIXLHVYDLGMXNRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVE 369
L K+ F ++++ LH YDLG+ NRD T+DQVT D AEAIKK+NVG+KCATITPDEKRVE
Sbjct: 25 LIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVE 84
Query: 370 EFXLKKMWKSPNGTIRNILGGTVFR 444
EF LK+MWKSPNGTIRNILGGTVFR
Sbjct: 85 EFKLKQMWKSPNGTIRNILGGTVFR 109
Score = 93.5 bits (222), Expect = 1e-18
Identities = 48/104 (46%), Positives = 61/104 (58%), Gaps = 2/104 (1%)
Frame = +2
Query: 449 AIICKNIPRLVTGWDKPIIIGRXAHADQYKATDFVVPGAGTLXIXFKPESG-EAIKXVVX 625
AIICKNIPRLV+GW KPIIIGR A+ DQY+ATDFVVPG G + I + P G + + +V
Sbjct: 111 AIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVH 170
Query: 626 EY-QGAXVALAMFXTXXXXXXXXXXXXXXXLDXKYPLYLXTXXT 754
+ +G VA+ M+ L +PLYL T T
Sbjct: 171 NFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNT 214
Score = 39.9 bits (89), Expect = 0.013
Identities = 21/32 (65%), Positives = 26/32 (81%)
Frame = +3
Query: 120 KINGWTVVVDIHCADEMTRIIWDLIKEKLILP 215
KI+G +VV ++ DEMTRIIW+LIKEKLI P
Sbjct: 4 KISGGSVV-EMQ-GDEMTRIIWELIKEKLIFP 33
>AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 138 bits (333), Expect = 3e-32
Identities = 63/85 (74%), Positives = 73/85 (85%)
Frame = +1
Query: 190 LSKKS*FFLFLDIXLHVYDLGMXNRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVE 369
L K+ F ++++ LH YDLG+ NRD T+DQVT D AEAIKK+NVG+KCATITPDEKRVE
Sbjct: 25 LIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVE 84
Query: 370 EFXLKKMWKSPNGTIRNILGGTVFR 444
EF LK+MWKSPNGTIRNILGGTVFR
Sbjct: 85 EFKLKQMWKSPNGTIRNILGGTVFR 109
Score = 93.5 bits (222), Expect = 1e-18
Identities = 48/104 (46%), Positives = 61/104 (58%), Gaps = 2/104 (1%)
Frame = +2
Query: 449 AIICKNIPRLVTGWDKPIIIGRXAHADQYKATDFVVPGAGTLXIXFKPESG-EAIKXVVX 625
AIICKNIPRLV+GW KPIIIGR A+ DQY+ATDFVVPG G + I + P G + + +V
Sbjct: 111 AIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVH 170
Query: 626 EY-QGAXVALAMFXTXXXXXXXXXXXXXXXLDXKYPLYLXTXXT 754
+ +G VA+ M+ L +PLYL T T
Sbjct: 171 NFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNT 214
Score = 39.9 bits (89), Expect = 0.013
Identities = 21/32 (65%), Positives = 26/32 (81%)
Frame = +3
Query: 120 KINGWTVVVDIHCADEMTRIIWDLIKEKLILP 215
KI+G +VV ++ DEMTRIIW+LIKEKLI P
Sbjct: 4 KISGGSVV-EMQ-GDEMTRIIWELIKEKLIFP 33
>AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 138 bits (333), Expect = 3e-32
Identities = 63/85 (74%), Positives = 73/85 (85%)
Frame = +1
Query: 190 LSKKS*FFLFLDIXLHVYDLGMXNRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVE 369
L K+ F ++++ LH YDLG+ NRD T+DQVT D AEAIKK+NVG+KCATITPDEKRVE
Sbjct: 25 LIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVE 84
Query: 370 EFXLKKMWKSPNGTIRNILGGTVFR 444
EF LK+MWKSPNGTIRNILGGTVFR
Sbjct: 85 EFKLKQMWKSPNGTIRNILGGTVFR 109
Score = 93.5 bits (222), Expect = 1e-18
Identities = 48/104 (46%), Positives = 61/104 (58%), Gaps = 2/104 (1%)
Frame = +2
Query: 449 AIICKNIPRLVTGWDKPIIIGRXAHADQYKATDFVVPGAGTLXIXFKPESG-EAIKXVVX 625
AIICKNIPRLV+GW KPIIIGR A+ DQY+ATDFVVPG G + I + P G + + +V
Sbjct: 111 AIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVH 170
Query: 626 EY-QGAXVALAMFXTXXXXXXXXXXXXXXXLDXKYPLYLXTXXT 754
+ +G VA+ M+ L +PLYL T T
Sbjct: 171 NFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNT 214
Score = 39.9 bits (89), Expect = 0.013
Identities = 21/32 (65%), Positives = 26/32 (81%)
Frame = +3
Query: 120 KINGWTVVVDIHCADEMTRIIWDLIKEKLILP 215
KI+G +VV ++ DEMTRIIW+LIKEKLI P
Sbjct: 4 KISGGSVV-EMQ-GDEMTRIIWELIKEKLIFP 33
>AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein.
Length = 414
Score = 138 bits (333), Expect = 3e-32
Identities = 63/85 (74%), Positives = 73/85 (85%)
Frame = +1
Query: 190 LSKKS*FFLFLDIXLHVYDLGMXNRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVE 369
L K+ F ++++ LH YDLG+ NRD T+DQVT D AEAIKK+NVG+KCATITPDEKRVE
Sbjct: 25 LIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVE 84
Query: 370 EFXLKKMWKSPNGTIRNILGGTVFR 444
EF LK+MWKSPNGTIRNILGGTVFR
Sbjct: 85 EFKLKQMWKSPNGTIRNILGGTVFR 109
Score = 93.5 bits (222), Expect = 1e-18
Identities = 48/104 (46%), Positives = 61/104 (58%), Gaps = 2/104 (1%)
Frame = +2
Query: 449 AIICKNIPRLVTGWDKPIIIGRXAHADQYKATDFVVPGAGTLXIXFKPESG-EAIKXVVX 625
AIICKNIPRLV+GW KPIIIGR A+ DQY+ATDFVVPG G + I + P G + + +V
Sbjct: 111 AIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVH 170
Query: 626 EY-QGAXVALAMFXTXXXXXXXXXXXXXXXLDXKYPLYLXTXXT 754
+ +G VA+ M+ L +PLYL T T
Sbjct: 171 NFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNT 214
Score = 39.9 bits (89), Expect = 0.013
Identities = 21/32 (65%), Positives = 26/32 (81%)
Frame = +3
Query: 120 KINGWTVVVDIHCADEMTRIIWDLIKEKLILP 215
KI+G +VV ++ DEMTRIIW+LIKEKLI P
Sbjct: 4 KISGGSVV-EMQ-GDEMTRIIWELIKEKLIFP 33
>DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenase 1
protein.
Length = 371
Score = 136 bits (329), Expect = 1e-31
Identities = 61/78 (78%), Positives = 70/78 (89%)
Frame = +1
Query: 211 FLFLDIXLHVYDLGMXNRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVEEFXLKKM 390
F ++++ LH YDLG+ NRD T+DQVT D AEAIKK+NVG+KCATITPDEKRVEEF LK+M
Sbjct: 3 FPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQM 62
Query: 391 WKSPNGTIRNILGGTVFR 444
WKSPNGTIRNILGGTVFR
Sbjct: 63 WKSPNGTIRNILGGTVFR 80
Score = 93.5 bits (222), Expect = 1e-18
Identities = 48/104 (46%), Positives = 61/104 (58%), Gaps = 2/104 (1%)
Frame = +2
Query: 449 AIICKNIPRLVTGWDKPIIIGRXAHADQYKATDFVVPGAGTLXIXFKPESG-EAIKXVVX 625
AIICKNIPRLV+GW KPIIIGR A+ DQY+ATDFVVPG G + I + P G + + +V
Sbjct: 82 AIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVH 141
Query: 626 EY-QGAXVALAMFXTXXXXXXXXXXXXXXXLDXKYPLYLXTXXT 754
+ +G VA+ M+ L +PLYL T T
Sbjct: 142 NFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNT 185
>CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 135 bits (327), Expect = 2e-31
Identities = 62/85 (72%), Positives = 72/85 (84%)
Frame = +1
Query: 190 LSKKS*FFLFLDIXLHVYDLGMXNRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVE 369
L K+ ++++ LH YDLG+ NRD T+DQVT D AEAIKK+NVG+KCATITPDEKRVE
Sbjct: 25 LIKEKLIIPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVE 84
Query: 370 EFXLKKMWKSPNGTIRNILGGTVFR 444
EF LK+MWKSPNGTIRNILGGTVFR
Sbjct: 85 EFKLKQMWKSPNGTIRNILGGTVFR 109
Score = 91.9 bits (218), Expect = 3e-18
Identities = 47/104 (45%), Positives = 61/104 (58%), Gaps = 2/104 (1%)
Frame = +2
Query: 449 AIICKNIPRLVTGWDKPIIIGRXAHADQYKATDFVVPGAGTLXIXFKPESG-EAIKXVVX 625
AIICKNIPRLV+GW +PIIIGR A+ DQY+ATDFVVPG G + I + P G + + +V
Sbjct: 111 AIICKNIPRLVSGWVEPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVH 170
Query: 626 EY-QGAXVALAMFXTXXXXXXXXXXXXXXXLDXKYPLYLXTXXT 754
+ +G VA+ M+ L +PLYL T T
Sbjct: 171 NFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNT 214
Score = 40.7 bits (91), Expect = 0.007
Identities = 21/32 (65%), Positives = 27/32 (84%)
Frame = +3
Query: 120 KINGWTVVVDIHCADEMTRIIWDLIKEKLILP 215
KI+G +VV ++ DEMTRIIW+LIKEKLI+P
Sbjct: 4 KISGGSVV-EMQ-GDEMTRIIWELIKEKLIIP 33
>X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase
(NADP+) protein.
Length = 452
Score = 127 bits (306), Expect = 6e-29
Identities = 58/75 (77%), Positives = 65/75 (86%)
Frame = +1
Query: 220 LDIXLHVYDLGMXNRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVEEFXLKKMWKS 399
+DI L +DLG+ NRD+TDDQVTID A A +KY+V +KCATITPDE RVEEF LKKMWKS
Sbjct: 75 VDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKS 134
Query: 400 PNGTIRNILGGTVFR 444
PNGTIRNILGGTVFR
Sbjct: 135 PNGTIRNILGGTVFR 149
Score = 93.5 bits (222), Expect = 1e-18
Identities = 46/102 (45%), Positives = 55/102 (53%), Gaps = 1/102 (0%)
Frame = +2
Query: 452 IICKNIPRLVTGWDKPIIIGRXAHADQYKATDFVVPGAGTLXIXFKPESGEAIK-XVVXE 628
IICKNIPRLV GW KPI IGR AH DQYKATDFV AGT + F P+ G +K V
Sbjct: 152 IICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYN 211
Query: 629 YQGAXVALAMFXTXXXXXXXXXXXXXXXLDXKYPLYLXTXXT 754
+ V + M+ T + K+PLY+ T T
Sbjct: 212 FPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNT 253
Score = 37.5 bits (83), Expect = 0.067
Identities = 16/18 (88%), Positives = 16/18 (88%)
Frame = +3
Query: 162 DEMTRIIWDLIKEKLILP 215
DEMTRIIW IKEKLILP
Sbjct: 56 DEMTRIIWQFIKEKLILP 73
>BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 127 bits (306), Expect = 6e-29
Identities = 58/75 (77%), Positives = 65/75 (86%)
Frame = +1
Query: 220 LDIXLHVYDLGMXNRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVEEFXLKKMWKS 399
+DI L +DLG+ NRD+TDDQVTID A A +KY+V +KCATITPDE RVEEF LKKMWKS
Sbjct: 75 VDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKS 134
Query: 400 PNGTIRNILGGTVFR 444
PNGTIRNILGGTVFR
Sbjct: 135 PNGTIRNILGGTVFR 149
Score = 93.5 bits (222), Expect = 1e-18
Identities = 46/102 (45%), Positives = 55/102 (53%), Gaps = 1/102 (0%)
Frame = +2
Query: 452 IICKNIPRLVTGWDKPIIIGRXAHADQYKATDFVVPGAGTLXIXFKPESGEAIK-XVVXE 628
IICKNIPRLV GW KPI IGR AH DQYKATDFV AGT + F P+ G +K V
Sbjct: 152 IICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYN 211
Query: 629 YQGAXVALAMFXTXXXXXXXXXXXXXXXLDXKYPLYLXTXXT 754
+ V + M+ T + K+PLY+ T T
Sbjct: 212 FPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNT 253
Score = 37.5 bits (83), Expect = 0.067
Identities = 16/18 (88%), Positives = 16/18 (88%)
Frame = +3
Query: 162 DEMTRIIWDLIKEKLILP 215
DEMTRIIW IKEKLILP
Sbjct: 56 DEMTRIIWQFIKEKLILP 73
>BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 127 bits (306), Expect = 6e-29
Identities = 58/75 (77%), Positives = 65/75 (86%)
Frame = +1
Query: 220 LDIXLHVYDLGMXNRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVEEFXLKKMWKS 399
+DI L +DLG+ NRD+TDDQVTID A A +KY+V +KCATITPDE RVEEF LKKMWKS
Sbjct: 75 VDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKS 134
Query: 400 PNGTIRNILGGTVFR 444
PNGTIRNILGGTVFR
Sbjct: 135 PNGTIRNILGGTVFR 149
Score = 93.5 bits (222), Expect = 1e-18
Identities = 46/102 (45%), Positives = 55/102 (53%), Gaps = 1/102 (0%)
Frame = +2
Query: 452 IICKNIPRLVTGWDKPIIIGRXAHADQYKATDFVVPGAGTLXIXFKPESGEAIK-XVVXE 628
IICKNIPRLV GW KPI IGR AH DQYKATDFV AGT + F P+ G +K V
Sbjct: 152 IICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYN 211
Query: 629 YQGAXVALAMFXTXXXXXXXXXXXXXXXLDXKYPLYLXTXXT 754
+ V + M+ T + K+PLY+ T T
Sbjct: 212 FPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNT 253
Score = 37.5 bits (83), Expect = 0.067
Identities = 16/18 (88%), Positives = 16/18 (88%)
Frame = +3
Query: 162 DEMTRIIWDLIKEKLILP 215
DEMTRIIW IKEKLILP
Sbjct: 56 DEMTRIIWQFIKEKLILP 73
>AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial precursor variant protein.
Length = 452
Score = 127 bits (306), Expect = 6e-29
Identities = 58/75 (77%), Positives = 65/75 (86%)
Frame = +1
Query: 220 LDIXLHVYDLGMXNRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVEEFXLKKMWKS 399
+DI L +DLG+ NRD+TDDQVTID A A +KY+V +KCATITPDE RVEEF LKKMWKS
Sbjct: 75 VDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKS 134
Query: 400 PNGTIRNILGGTVFR 444
PNGTIRNILGGTVFR
Sbjct: 135 PNGTIRNILGGTVFR 149
Score = 93.5 bits (222), Expect = 1e-18
Identities = 46/102 (45%), Positives = 55/102 (53%), Gaps = 1/102 (0%)
Frame = +2
Query: 452 IICKNIPRLVTGWDKPIIIGRXAHADQYKATDFVVPGAGTLXIXFKPESGEAIK-XVVXE 628
IICKNIPRLV GW KPI IGR AH DQYKATDFV AGT + F P+ G +K V
Sbjct: 152 IICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYN 211
Query: 629 YQGAXVALAMFXTXXXXXXXXXXXXXXXLDXKYPLYLXTXXT 754
+ V + M+ T + K+PLY+ T T
Sbjct: 212 FPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNT 253
Score = 37.5 bits (83), Expect = 0.067
Identities = 16/18 (88%), Positives = 16/18 (88%)
Frame = +3
Query: 162 DEMTRIIWDLIKEKLILP 215
DEMTRIIW IKEKLILP
Sbjct: 56 DEMTRIIWQFIKEKLILP 73
>U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase
protein.
Length = 419
Score = 125 bits (301), Expect = 3e-28
Identities = 57/75 (76%), Positives = 64/75 (85%)
Frame = +1
Query: 220 LDIXLHVYDLGMXNRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVEEFXLKKMWKS 399
LD+ L +DLG+ NRD+TDDQVTID A A +KY+V +KCATITPDE RVEEF LKKMWKS
Sbjct: 42 LDVQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKS 101
Query: 400 PNGTIRNILGGTVFR 444
PNGTIRNI GGTVFR
Sbjct: 102 PNGTIRNIHGGTVFR 116
Score = 93.5 bits (222), Expect = 1e-18
Identities = 46/102 (45%), Positives = 55/102 (53%), Gaps = 1/102 (0%)
Frame = +2
Query: 452 IICKNIPRLVTGWDKPIIIGRXAHADQYKATDFVVPGAGTLXIXFKPESGEAIK-XVVXE 628
IICKNIPRLV GW KPI IGR AH DQYKATDFV AGT + F P+ G +K V
Sbjct: 119 IICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYN 178
Query: 629 YQGAXVALAMFXTXXXXXXXXXXXXXXXLDXKYPLYLXTXXT 754
+ V + M+ T + K+PLY+ T T
Sbjct: 179 FPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNT 220
>U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic
NADP-dependent isocitrate dehydrogenase protein.
Length = 154
Score = 93.5 bits (222), Expect = 1e-18
Identities = 48/104 (46%), Positives = 61/104 (58%), Gaps = 2/104 (1%)
Frame = +2
Query: 449 AIICKNIPRLVTGWDKPIIIGRXAHADQYKATDFVVPGAGTLXIXFKPESG-EAIKXVVX 625
AIICKNIPRLV+GW KPIIIGR A+ DQY+ATDFVVPG G + I + P G + + +V
Sbjct: 12 AIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVH 71
Query: 626 EY-QGAXVALAMFXTXXXXXXXXXXXXXXXLDXKYPLYLXTXXT 754
+ +G VA+ M+ L +PLYL T T
Sbjct: 72 NFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNT 115
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 99,704,402
Number of Sequences: 237096
Number of extensions: 1906392
Number of successful extensions: 3134
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 3020
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3127
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11881370308
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -