Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP12_F_M22
(897 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X71125-1|CAA50438.1| 361|Homo sapiens glutaminyl-peptide cyclot... 101 3e-21
BC047756-1|AAH47756.1| 361|Homo sapiens glutaminyl-peptide cycl... 101 3e-21
BC036721-1|AAH36721.1| 361|Homo sapiens glutaminyl-peptide cycl... 101 3e-21
AC007391-1|AAY14804.1| 361|Homo sapiens unknown protein. 101 3e-21
X67731-1|CAA47961.1| 251|Homo sapiens glutaminyl-peptide cyclot... 91 5e-18
AK222636-1|BAD96356.1| 382|Homo sapiens glutaminyl-peptide cycl... 89 3e-17
AK172764-1|BAD18747.1| 382|Homo sapiens protein ( Homo sapiens ... 89 3e-17
AK000091-1|BAA90938.1| 382|Homo sapiens protein ( Homo sapiens ... 89 3e-17
>X71125-1|CAA50438.1| 361|Homo sapiens glutaminyl-peptide
cyclotransferase protein.
Length = 361
Score = 101 bits (243), Expect = 3e-21
Identities = 58/146 (39%), Positives = 83/146 (56%), Gaps = 6/146 (4%)
Frame = +2
Query: 302 QEKNFHEPHDFTDDDIKAIANLSDLDH-FKAVLNEILIPRVVGTPNHEKVGNYIANEMRT 478
+EKN+H+P ++ IA + + ++ L +LI R G+P +I ++
Sbjct: 38 EEKNYHQPAILNSSALRQIAEGTSISEMWQNDLQPLLIERYPGSPGSYAARQHIMQRIQR 97
Query: 479 M--GWSVTENVFPDHTPVFGTLNFXNIIAELNPNADRYLVLACHYDSKY---TREHVFVG 643
+ W + + F TP +G +F NII+ LNP A R+LVLACHYDSKY VFVG
Sbjct: 98 LQADWVLEIDTFLSQTP-YGYRSFSNIISTLNPTAKRHLVLACHYDSKYFSHWNNRVFVG 156
Query: 644 ATDSXVPCAMLLNLAKMMKXQLEXLK 721
ATDS VPCAM+L LA+ + +L LK
Sbjct: 157 ATDSAVPCAMMLELARALDKKLLSLK 182
>BC047756-1|AAH47756.1| 361|Homo sapiens glutaminyl-peptide
cyclotransferase (glutaminyl cyclase) protein.
Length = 361
Score = 101 bits (243), Expect = 3e-21
Identities = 58/146 (39%), Positives = 83/146 (56%), Gaps = 6/146 (4%)
Frame = +2
Query: 302 QEKNFHEPHDFTDDDIKAIANLSDLDH-FKAVLNEILIPRVVGTPNHEKVGNYIANEMRT 478
+EKN+H+P ++ IA + + ++ L +LI R G+P +I ++
Sbjct: 38 EEKNYHQPAILNSSALRQIAEGTSISEMWQNDLQPLLIERYPGSPGSYAARQHIMQRIQR 97
Query: 479 M--GWSVTENVFPDHTPVFGTLNFXNIIAELNPNADRYLVLACHYDSKY---TREHVFVG 643
+ W + + F TP +G +F NII+ LNP A R+LVLACHYDSKY VFVG
Sbjct: 98 LQADWVLEIDTFLSQTP-YGYRSFSNIISTLNPTAKRHLVLACHYDSKYFSHWNNRVFVG 156
Query: 644 ATDSXVPCAMLLNLAKMMKXQLEXLK 721
ATDS VPCAM+L LA+ + +L LK
Sbjct: 157 ATDSAVPCAMMLELARALDKKLLSLK 182
>BC036721-1|AAH36721.1| 361|Homo sapiens glutaminyl-peptide
cyclotransferase (glutaminyl cyclase) protein.
Length = 361
Score = 101 bits (243), Expect = 3e-21
Identities = 58/146 (39%), Positives = 83/146 (56%), Gaps = 6/146 (4%)
Frame = +2
Query: 302 QEKNFHEPHDFTDDDIKAIANLSDLDH-FKAVLNEILIPRVVGTPNHEKVGNYIANEMRT 478
+EKN+H+P ++ IA + + ++ L +LI R G+P +I ++
Sbjct: 38 EEKNYHQPAILNSSALRQIAEGTSISEMWQNDLQPLLIERYPGSPGSYAARQHIMQRIQR 97
Query: 479 M--GWSVTENVFPDHTPVFGTLNFXNIIAELNPNADRYLVLACHYDSKY---TREHVFVG 643
+ W + + F TP +G +F NII+ LNP A R+LVLACHYDSKY VFVG
Sbjct: 98 LQADWVLEIDTFLSQTP-YGYRSFSNIISTLNPTAKRHLVLACHYDSKYFSHWNNRVFVG 156
Query: 644 ATDSXVPCAMLLNLAKMMKXQLEXLK 721
ATDS VPCAM+L LA+ + +L LK
Sbjct: 157 ATDSAVPCAMMLELARALDKKLLSLK 182
>AC007391-1|AAY14804.1| 361|Homo sapiens unknown protein.
Length = 361
Score = 101 bits (243), Expect = 3e-21
Identities = 58/146 (39%), Positives = 83/146 (56%), Gaps = 6/146 (4%)
Frame = +2
Query: 302 QEKNFHEPHDFTDDDIKAIANLSDLDH-FKAVLNEILIPRVVGTPNHEKVGNYIANEMRT 478
+EKN+H+P ++ IA + + ++ L +LI R G+P +I ++
Sbjct: 38 EEKNYHQPAILNSSALRQIAEGTSISEMWQNDLQPLLIERYPGSPGSYAARQHIMQRIQR 97
Query: 479 M--GWSVTENVFPDHTPVFGTLNFXNIIAELNPNADRYLVLACHYDSKY---TREHVFVG 643
+ W + + F TP +G +F NII+ LNP A R+LVLACHYDSKY VFVG
Sbjct: 98 LQADWVLEIDTFLSQTP-YGYRSFSNIISTLNPTAKRHLVLACHYDSKYFSHWNNRVFVG 156
Query: 644 ATDSXVPCAMLLNLAKMMKXQLEXLK 721
ATDS VPCAM+L LA+ + +L LK
Sbjct: 157 ATDSAVPCAMMLELARALDKKLLSLK 182
>X67731-1|CAA47961.1| 251|Homo sapiens glutaminyl-peptide
cyclotransferase protein.
Length = 251
Score = 91.1 bits (216), Expect = 5e-18
Identities = 51/114 (44%), Positives = 67/114 (58%), Gaps = 5/114 (4%)
Frame = +2
Query: 395 LNEILIPRVVGTPNHEKVGNYIANEMRTM--GWSVTENVFPDHTPVFGTLNFXNIIAELN 568
L +LI R G+P +I ++ + W + + F TP +G +F NII+ LN
Sbjct: 4 LRPLLIERYPGSPGSYAARQHIMQRIQRLQADWVLEIDTFLSQTP-YGYRSFSNIISTLN 62
Query: 569 PNADRYLVLACHYDSKY---TREHVFVGATDSXVPCAMLLNLAKMMKXQLEXLK 721
P A R+LVLACHYDSKY VFVGATDS VPCAM+L LA+ + +L LK
Sbjct: 63 PTAKRHLVLACHYDSKYFSHWNNRVFVGATDSAVPCAMMLELARALDKKLLSLK 116
>AK222636-1|BAD96356.1| 382|Homo sapiens glutaminyl-peptide
cyclotransferase-like variant protein.
Length = 382
Score = 88.6 bits (210), Expect = 3e-17
Identities = 49/128 (38%), Positives = 72/128 (56%), Gaps = 4/128 (3%)
Frame = +2
Query: 350 KAIANLSDLDHFKAVLNEILIPRVVGTPNHEKVGNYIANEMR--TMGWSVTENVFPDHTP 523
+ + L + L +L+ R G+P + +V ++ +R T GW V + F TP
Sbjct: 83 RVVGQLDPQRLWSTYLRPLLVVRTPGSPGNLQVRKFLEATLRSLTAGWHVELDPFTASTP 142
Query: 524 VFGTLNFXNIIAELNPNADRYLVLACHYDSKY--TREHVFVGATDSXVPCAMLLNLAKMM 697
+ G ++F N++A L+P A R+L LACHYDSK FVGATDS VPCA+LL LA+ +
Sbjct: 143 L-GPVDFGNVVATLDPRAARHLTLACHYDSKLFPPGSTPFVGATDSAVPCALLLELAQAL 201
Query: 698 KXQLEXLK 721
+L K
Sbjct: 202 DLELSRAK 209
>AK172764-1|BAD18747.1| 382|Homo sapiens protein ( Homo sapiens
cDNA FLJ23925 fis, clone COL03589. ).
Length = 382
Score = 88.6 bits (210), Expect = 3e-17
Identities = 49/128 (38%), Positives = 72/128 (56%), Gaps = 4/128 (3%)
Frame = +2
Query: 350 KAIANLSDLDHFKAVLNEILIPRVVGTPNHEKVGNYIANEMR--TMGWSVTENVFPDHTP 523
+ + L + L +L+ R G+P + +V ++ +R T GW V + F TP
Sbjct: 83 RVVGQLDPQRLWSTYLRPLLVVRTPGSPGNLQVRKFLEATLRSLTAGWHVELDPFTASTP 142
Query: 524 VFGTLNFXNIIAELNPNADRYLVLACHYDSKY--TREHVFVGATDSXVPCAMLLNLAKMM 697
+ G ++F N++A L+P A R+L LACHYDSK FVGATDS VPCA+LL LA+ +
Sbjct: 143 L-GPVDFGNVVATLDPRAARHLTLACHYDSKLFPPGSTPFVGATDSAVPCALLLELAQAL 201
Query: 698 KXQLEXLK 721
+L K
Sbjct: 202 DLELSRAK 209
>AK000091-1|BAA90938.1| 382|Homo sapiens protein ( Homo sapiens
cDNA FLJ20084 fis, clone COL03526. ).
Length = 382
Score = 88.6 bits (210), Expect = 3e-17
Identities = 49/128 (38%), Positives = 72/128 (56%), Gaps = 4/128 (3%)
Frame = +2
Query: 350 KAIANLSDLDHFKAVLNEILIPRVVGTPNHEKVGNYIANEMR--TMGWSVTENVFPDHTP 523
+ + L + L +L+ R G+P + +V ++ +R T GW V + F TP
Sbjct: 83 RVVGQLDPQRLWSTYLRPLLVVRTPGSPGNLQVRKFLEATLRSLTAGWHVELDPFTASTP 142
Query: 524 VFGTLNFXNIIAELNPNADRYLVLACHYDSKY--TREHVFVGATDSXVPCAMLLNLAKMM 697
+ G ++F N++A L+P A R+L LACHYDSK FVGATDS VPCA+LL LA+ +
Sbjct: 143 L-GPVDFGNVVATLDPRAARHLTLACHYDSKLFPPGSTPFVGATDSAVPCALLLELAQAL 201
Query: 698 KXQLEXLK 721
+L K
Sbjct: 202 DLELSRAK 209
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 106,139,743
Number of Sequences: 237096
Number of extensions: 1929740
Number of successful extensions: 3175
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 3059
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3163
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11548247776
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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