Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP12_F_J12
(894 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
L10413-1|AAA86285.1| 379|Homo sapiens farnesyl-protein transfer... 153 6e-37
L00634-1|AAA35853.1| 379|Homo sapiens farnesyl-protein transfer... 153 6e-37
BT009854-1|AAP88856.1| 379|Homo sapiens farnesyltransferase, CA... 153 6e-37
BC084566-1|AAH84566.1| 379|Homo sapiens farnesyltransferase, CA... 153 6e-37
BC017029-1|AAH17029.2| 376|Homo sapiens FNTA protein protein. 153 6e-37
BC037295-1|AAH37295.1| 214|Homo sapiens FNTA protein protein. 104 5e-22
Y08200-1|CAA69382.1| 567|Homo sapiens rab geranylgeranyl transf... 42 0.004
CR541797-1|CAG46596.1| 567|Homo sapiens RABGGTA protein. 42 0.004
BC003093-1|AAH03093.1| 567|Homo sapiens Rab geranylgeranyltrans... 42 0.004
>L10413-1|AAA86285.1| 379|Homo sapiens farnesyl-protein transferase
alpha-subunit protein.
Length = 379
Score = 153 bits (372), Expect = 6e-37
Identities = 65/106 (61%), Positives = 85/106 (80%)
Frame = +2
Query: 113 WIPYKERPEWSDVTPVPEDDGPNPVVVIAHSEKFEDVYDYFRAVLQSNEKSERVLHLTKD 292
++ Y++R EW+D+ PVP++DGPNPVV I +S+KF DVYDYFRAVLQ +E+SER LT+D
Sbjct: 63 YVLYRDRAEWADIDPVPQNDGPNPVVQIIYSDKFRDVYDYFRAVLQRDERSERAFKLTRD 122
Query: 293 ALELNPANYTVWQYRRDLLKHLNTDLRTELDYVEAVIKNSPKNYQV 430
A+ELN ANYTVW +RR LLK L DL E++Y+ A+I+ PKNYQV
Sbjct: 123 AIELNAANYTVWHFRRVLLKSLQKDLHEEMNYITAIIEEQPKNYQV 168
Score = 40.3 bits (90), Expect = 0.009
Identities = 23/70 (32%), Positives = 40/70 (57%), Gaps = 2/70 (2%)
Frame = +2
Query: 221 VYDYFRAVLQSNEKS--ERVLHLTKDALELNPANYTVWQYRRDLLKHLNTDLRTELDYVE 394
V+ + R +L+S +K E + ++T +E P NY VW +RR L++ L D EL+++
Sbjct: 133 VWHFRRVLLKSLQKDLHEEMNYITA-IIEEQPKNYQVWHHRRVLVEWLR-DPSQELEFIA 190
Query: 395 AVIKNSPKNY 424
++ KNY
Sbjct: 191 DILNQDAKNY 200
Score = 33.5 bits (73), Expect = 1.1
Identities = 19/80 (23%), Positives = 36/80 (45%)
Frame = +2
Query: 191 VIAHSEKFEDVYDYFRAVLQSNEKSERVLHLTKDALELNPANYTVWQYRRDLLKHLNTDL 370
+I K V+ + R +++ + L D L + NY WQ+R+ +++
Sbjct: 158 IIEEQPKNYQVWHHRRVLVEWLRDPSQELEFIADILNQDAKNYHAWQHRQWVIQEFKL-W 216
Query: 371 RTELDYVEAVIKNSPKNYQV 430
EL YV+ ++K +N V
Sbjct: 217 DNELQYVDQLLKEDVRNNSV 236
>L00634-1|AAA35853.1| 379|Homo sapiens farnesyl-protein transferase
alpha-subunit protein.
Length = 379
Score = 153 bits (372), Expect = 6e-37
Identities = 65/106 (61%), Positives = 85/106 (80%)
Frame = +2
Query: 113 WIPYKERPEWSDVTPVPEDDGPNPVVVIAHSEKFEDVYDYFRAVLQSNEKSERVLHLTKD 292
++ Y++R EW+D+ PVP++DGPNPVV I +S+KF DVYDYFRAVLQ +E+SER LT+D
Sbjct: 63 YVLYRDRAEWADIDPVPQNDGPNPVVQIIYSDKFRDVYDYFRAVLQRDERSERAFKLTRD 122
Query: 293 ALELNPANYTVWQYRRDLLKHLNTDLRTELDYVEAVIKNSPKNYQV 430
A+ELN ANYTVW +RR LLK L DL E++Y+ A+I+ PKNYQV
Sbjct: 123 AIELNAANYTVWHFRRVLLKSLQKDLHEEMNYITAIIEEQPKNYQV 168
Score = 40.3 bits (90), Expect = 0.009
Identities = 23/70 (32%), Positives = 40/70 (57%), Gaps = 2/70 (2%)
Frame = +2
Query: 221 VYDYFRAVLQSNEKS--ERVLHLTKDALELNPANYTVWQYRRDLLKHLNTDLRTELDYVE 394
V+ + R +L+S +K E + ++T +E P NY VW +RR L++ L D EL+++
Sbjct: 133 VWHFRRVLLKSLQKDLHEEMNYITA-IIEEQPKNYQVWHHRRVLVEWLR-DPSQELEFIA 190
Query: 395 AVIKNSPKNY 424
++ KNY
Sbjct: 191 DILNQDAKNY 200
Score = 33.5 bits (73), Expect = 1.1
Identities = 19/80 (23%), Positives = 36/80 (45%)
Frame = +2
Query: 191 VIAHSEKFEDVYDYFRAVLQSNEKSERVLHLTKDALELNPANYTVWQYRRDLLKHLNTDL 370
+I K V+ + R +++ + L D L + NY WQ+R+ +++
Sbjct: 158 IIEEQPKNYQVWHHRRVLVEWLRDPSQELEFIADILNQDAKNYHAWQHRQWVIQEFKL-W 216
Query: 371 RTELDYVEAVIKNSPKNYQV 430
EL YV+ ++K +N V
Sbjct: 217 DNELQYVDQLLKEDVRNNSV 236
>BT009854-1|AAP88856.1| 379|Homo sapiens farnesyltransferase, CAAX
box, alpha protein.
Length = 379
Score = 153 bits (372), Expect = 6e-37
Identities = 65/106 (61%), Positives = 85/106 (80%)
Frame = +2
Query: 113 WIPYKERPEWSDVTPVPEDDGPNPVVVIAHSEKFEDVYDYFRAVLQSNEKSERVLHLTKD 292
++ Y++R EW+D+ PVP++DGPNPVV I +S+KF DVYDYFRAVLQ +E+SER LT+D
Sbjct: 63 YVLYRDRAEWADIDPVPQNDGPNPVVQIIYSDKFRDVYDYFRAVLQRDERSERAFKLTRD 122
Query: 293 ALELNPANYTVWQYRRDLLKHLNTDLRTELDYVEAVIKNSPKNYQV 430
A+ELN ANYTVW +RR LLK L DL E++Y+ A+I+ PKNYQV
Sbjct: 123 AIELNAANYTVWHFRRVLLKSLQKDLHEEMNYITAIIEEQPKNYQV 168
Score = 40.3 bits (90), Expect = 0.009
Identities = 23/70 (32%), Positives = 40/70 (57%), Gaps = 2/70 (2%)
Frame = +2
Query: 221 VYDYFRAVLQSNEKS--ERVLHLTKDALELNPANYTVWQYRRDLLKHLNTDLRTELDYVE 394
V+ + R +L+S +K E + ++T +E P NY VW +RR L++ L D EL+++
Sbjct: 133 VWHFRRVLLKSLQKDLHEEMNYITA-IIEEQPKNYQVWHHRRVLVEWLR-DPSQELEFIA 190
Query: 395 AVIKNSPKNY 424
++ KNY
Sbjct: 191 DILNQDAKNY 200
Score = 33.5 bits (73), Expect = 1.1
Identities = 19/80 (23%), Positives = 36/80 (45%)
Frame = +2
Query: 191 VIAHSEKFEDVYDYFRAVLQSNEKSERVLHLTKDALELNPANYTVWQYRRDLLKHLNTDL 370
+I K V+ + R +++ + L D L + NY WQ+R+ +++
Sbjct: 158 IIEEQPKNYQVWHHRRVLVEWLRDPSQELEFIADILNQDAKNYHAWQHRQWVIQEFKL-W 216
Query: 371 RTELDYVEAVIKNSPKNYQV 430
EL YV+ ++K +N V
Sbjct: 217 DNELQYVDQLLKEDVRNNSV 236
>BC084566-1|AAH84566.1| 379|Homo sapiens farnesyltransferase, CAAX
box, alpha protein.
Length = 379
Score = 153 bits (372), Expect = 6e-37
Identities = 65/106 (61%), Positives = 85/106 (80%)
Frame = +2
Query: 113 WIPYKERPEWSDVTPVPEDDGPNPVVVIAHSEKFEDVYDYFRAVLQSNEKSERVLHLTKD 292
++ Y++R EW+D+ PVP++DGPNPVV I +S+KF DVYDYFRAVLQ +E+SER LT+D
Sbjct: 63 YVLYRDRAEWADIDPVPQNDGPNPVVQIIYSDKFRDVYDYFRAVLQRDERSERAFKLTRD 122
Query: 293 ALELNPANYTVWQYRRDLLKHLNTDLRTELDYVEAVIKNSPKNYQV 430
A+ELN ANYTVW +RR LLK L DL E++Y+ A+I+ PKNYQV
Sbjct: 123 AIELNAANYTVWHFRRVLLKSLQKDLHEEMNYITAIIEEQPKNYQV 168
Score = 40.3 bits (90), Expect = 0.009
Identities = 23/70 (32%), Positives = 40/70 (57%), Gaps = 2/70 (2%)
Frame = +2
Query: 221 VYDYFRAVLQSNEKS--ERVLHLTKDALELNPANYTVWQYRRDLLKHLNTDLRTELDYVE 394
V+ + R +L+S +K E + ++T +E P NY VW +RR L++ L D EL+++
Sbjct: 133 VWHFRRVLLKSLQKDLHEEMNYITA-IIEEQPKNYQVWHHRRVLVEWLR-DPSQELEFIA 190
Query: 395 AVIKNSPKNY 424
++ KNY
Sbjct: 191 DILNQDAKNY 200
Score = 33.5 bits (73), Expect = 1.1
Identities = 19/80 (23%), Positives = 36/80 (45%)
Frame = +2
Query: 191 VIAHSEKFEDVYDYFRAVLQSNEKSERVLHLTKDALELNPANYTVWQYRRDLLKHLNTDL 370
+I K V+ + R +++ + L D L + NY WQ+R+ +++
Sbjct: 158 IIEEQPKNYQVWHHRRVLVEWLRDPSQELEFIADILNQDAKNYHAWQHRQWVIQEFKL-W 216
Query: 371 RTELDYVEAVIKNSPKNYQV 430
EL YV+ ++K +N V
Sbjct: 217 DNELQYVDQLLKEDVRNNSV 236
>BC017029-1|AAH17029.2| 376|Homo sapiens FNTA protein protein.
Length = 376
Score = 153 bits (372), Expect = 6e-37
Identities = 65/106 (61%), Positives = 85/106 (80%)
Frame = +2
Query: 113 WIPYKERPEWSDVTPVPEDDGPNPVVVIAHSEKFEDVYDYFRAVLQSNEKSERVLHLTKD 292
++ Y++R EW+D+ PVP++DGPNPVV I +S+KF DVYDYFRAVLQ +E+SER LT+D
Sbjct: 60 YVLYRDRAEWADIDPVPQNDGPNPVVQIIYSDKFRDVYDYFRAVLQRDERSERAFKLTRD 119
Query: 293 ALELNPANYTVWQYRRDLLKHLNTDLRTELDYVEAVIKNSPKNYQV 430
A+ELN ANYTVW +RR LLK L DL E++Y+ A+I+ PKNYQV
Sbjct: 120 AIELNAANYTVWHFRRVLLKSLQKDLHEEMNYITAIIEEQPKNYQV 165
Score = 40.3 bits (90), Expect = 0.009
Identities = 23/70 (32%), Positives = 40/70 (57%), Gaps = 2/70 (2%)
Frame = +2
Query: 221 VYDYFRAVLQSNEKS--ERVLHLTKDALELNPANYTVWQYRRDLLKHLNTDLRTELDYVE 394
V+ + R +L+S +K E + ++T +E P NY VW +RR L++ L D EL+++
Sbjct: 130 VWHFRRVLLKSLQKDLHEEMNYITA-IIEEQPKNYQVWHHRRVLVEWLR-DPSQELEFIA 187
Query: 395 AVIKNSPKNY 424
++ KNY
Sbjct: 188 DILNQDAKNY 197
Score = 33.5 bits (73), Expect = 1.1
Identities = 19/80 (23%), Positives = 36/80 (45%)
Frame = +2
Query: 191 VIAHSEKFEDVYDYFRAVLQSNEKSERVLHLTKDALELNPANYTVWQYRRDLLKHLNTDL 370
+I K V+ + R +++ + L D L + NY WQ+R+ +++
Sbjct: 155 IIEEQPKNYQVWHHRRVLVEWLRDPSQELEFIADILNQDAKNYHAWQHRQWVIQEFKL-W 213
Query: 371 RTELDYVEAVIKNSPKNYQV 430
EL YV+ ++K +N V
Sbjct: 214 DNELQYVDQLLKEDVRNNSV 233
>BC037295-1|AAH37295.1| 214|Homo sapiens FNTA protein protein.
Length = 214
Score = 104 bits (249), Expect = 5e-22
Identities = 46/71 (64%), Positives = 56/71 (78%)
Frame = +2
Query: 218 DVYDYFRAVLQSNEKSERVLHLTKDALELNPANYTVWQYRRDLLKHLNTDLRTELDYVEA 397
DVYDYFRAVLQ +E+SER LT+DA+ELN ANYTVW +RR LLK L DL E++Y+ A
Sbjct: 7 DVYDYFRAVLQRDERSERAFKLTRDAIELNAANYTVWHFRRVLLKSLQKDLHEEMNYITA 66
Query: 398 VIKNSPKNYQV 430
+I+ PKNYQV
Sbjct: 67 IIEEQPKNYQV 77
Score = 40.3 bits (90), Expect = 0.009
Identities = 23/70 (32%), Positives = 40/70 (57%), Gaps = 2/70 (2%)
Frame = +2
Query: 221 VYDYFRAVLQSNEKS--ERVLHLTKDALELNPANYTVWQYRRDLLKHLNTDLRTELDYVE 394
V+ + R +L+S +K E + ++T +E P NY VW +RR L++ L D EL+++
Sbjct: 42 VWHFRRVLLKSLQKDLHEEMNYITA-IIEEQPKNYQVWHHRRVLVEWLR-DPSQELEFIA 99
Query: 395 AVIKNSPKNY 424
++ KNY
Sbjct: 100 DILNQDAKNY 109
Score = 33.5 bits (73), Expect = 1.1
Identities = 19/80 (23%), Positives = 36/80 (45%)
Frame = +2
Query: 191 VIAHSEKFEDVYDYFRAVLQSNEKSERVLHLTKDALELNPANYTVWQYRRDLLKHLNTDL 370
+I K V+ + R +++ + L D L + NY WQ+R+ +++
Sbjct: 67 IIEEQPKNYQVWHHRRVLVEWLRDPSQELEFIADILNQDAKNYHAWQHRQWVIQEFKL-W 125
Query: 371 RTELDYVEAVIKNSPKNYQV 430
EL YV+ ++K +N V
Sbjct: 126 DNELQYVDQLLKEDVRNNSV 145
>Y08200-1|CAA69382.1| 567|Homo sapiens rab geranylgeranyl
transferase protein.
Length = 567
Score = 41.5 bits (93), Expect = 0.004
Identities = 23/68 (33%), Positives = 37/68 (54%), Gaps = 9/68 (13%)
Frame = +2
Query: 248 QSNEKSERVLHLTKDALELNPANYTVWQYRRDLLKHLNTD---------LRTELDYVEAV 400
Q+ E E VL LT L NP T+W RR++L+ L T ++ EL ++E+
Sbjct: 40 QAGELDESVLELTSQILGANPDFATLWNCRREVLQQLETQKSPEELAALVKAELGFLESC 99
Query: 401 IKNSPKNY 424
++ +PK+Y
Sbjct: 100 LRVNPKSY 107
>CR541797-1|CAG46596.1| 567|Homo sapiens RABGGTA protein.
Length = 567
Score = 41.5 bits (93), Expect = 0.004
Identities = 23/68 (33%), Positives = 37/68 (54%), Gaps = 9/68 (13%)
Frame = +2
Query: 248 QSNEKSERVLHLTKDALELNPANYTVWQYRRDLLKHLNTD---------LRTELDYVEAV 400
Q+ E E VL LT L NP T+W RR++L+ L T ++ EL ++E+
Sbjct: 40 QAGELDESVLELTSQILGANPDFATLWNCRREVLQQLETQKSPEELAALVKAELGFLESC 99
Query: 401 IKNSPKNY 424
++ +PK+Y
Sbjct: 100 LRVNPKSY 107
>BC003093-1|AAH03093.1| 567|Homo sapiens Rab
geranylgeranyltransferase, alpha subunit protein.
Length = 567
Score = 41.5 bits (93), Expect = 0.004
Identities = 23/68 (33%), Positives = 37/68 (54%), Gaps = 9/68 (13%)
Frame = +2
Query: 248 QSNEKSERVLHLTKDALELNPANYTVWQYRRDLLKHLNTD---------LRTELDYVEAV 400
Q+ E E VL LT L NP T+W RR++L+ L T ++ EL ++E+
Sbjct: 40 QAGELDESVLELTSQILGANPDFATLWNCRREVLQQLETQKSPEELAALVKAELGFLESC 99
Query: 401 IKNSPKNY 424
++ +PK+Y
Sbjct: 100 LRVNPKSY 107
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 100,282,562
Number of Sequences: 237096
Number of extensions: 1906837
Number of successful extensions: 6453
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 6355
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6453
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11492727354
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -