Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP12_F_F13
(858 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U24253-1|AAC13871.1| 353|Homo sapiens folylpolyglutamate synthe... 129 1e-29
M98045-1|AAA35852.1| 545|Homo sapiens folylpolyglutamate synthe... 129 1e-29
BC064393-1|AAH64393.1| 587|Homo sapiens folylpolyglutamate synt... 129 1e-29
AL162586-11|CAI39770.1| 587|Homo sapiens folylpolyglutamate syn... 129 1e-29
AL162586-10|CAI39769.1| 375|Homo sapiens folylpolyglutamate syn... 129 1e-29
AL162586-14|CAI39773.1| 537|Homo sapiens folylpolyglutamate syn... 118 3e-26
AL162586-13|CAI39772.1| 265|Homo sapiens folylpolyglutamate syn... 118 3e-26
AL162586-12|CAI39771.1| 194|Homo sapiens folylpolyglutamate syn... 118 3e-26
BT006639-1|AAP35285.1| 174|Homo sapiens folylpolyglutamate synt... 94 7e-19
U40868-1|AAA87568.1| 486|Homo sapiens folylpolyglutamate synthe... 76 2e-13
U14939-1|AAA85815.1| 107|Homo sapiens folylpolyglutamate synthe... 69 3e-11
AY007211-2|AAL08406.1| 53|Homo sapiens folylpolyglutamate synt... 36 0.19
AY007211-1|AAL08407.1| 75|Homo sapiens folylpolyglutamate synt... 36 0.19
AB030241-1|BAB39849.1| 521|Homo sapiens DRCTNNB1A protein. 31 7.1
U88528-1|AAC04325.1| 395|Homo sapiens transcription factor LZIP... 30 9.4
U59629-1|AAD09210.1| 371|Homo sapiens transcription factor LZIP... 30 9.4
BC010158-1|AAH10158.1| 371|Homo sapiens cAMP responsive element... 30 9.4
BC009402-1|AAH09402.1| 371|Homo sapiens cAMP responsive element... 30 9.4
AL133410-7|CAI10980.1| 371|Homo sapiens cAMP responsive element... 30 9.4
AF211848-1|AAG43528.1| 371|Homo sapiens cAMP responsive element... 30 9.4
AF211847-1|AAG43527.1| 371|Homo sapiens cAMP responsive element... 30 9.4
AF029674-1|AAB84166.1| 371|Homo sapiens basic leucine zipper pr... 30 9.4
AF009368-1|AAB69652.1| 371|Homo sapiens Luman protein. 30 9.4
>U24253-1|AAC13871.1| 353|Homo sapiens folylpolyglutamate
synthetase protein.
Length = 353
Score = 129 bits (311), Expect = 1e-29
Identities = 62/124 (50%), Positives = 85/124 (68%)
Frame = +1
Query: 373 YEDAVRKLNRLQSNKSTIEQIRKDIRTGQKCTNLEDMENYLSRTGVTMSKLDELSVVHVA 552
Y+DAVR LN LQ+N +EQ+++ + G T LE ME YL+R+G+ + LD L+++HV
Sbjct: 45 YQDAVRMLNTLQTNAGYLEQVKR--QRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVT 102
Query: 553 GTKGKGSTSAMCESILRHHGFRTGFYSSPHLXAVRXRVRLXXRVISEXMFAXYFHXVHXR 732
GTKGKGST A E ILR +G +TGF+SSPHL VR R+R+ + IS +F YF ++ R
Sbjct: 103 GTKGKGSTCAFTECILRSYGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHR 162
Query: 733 LEXT 744
LE T
Sbjct: 163 LEET 166
>M98045-1|AAA35852.1| 545|Homo sapiens folylpolyglutamate
synthetase protein.
Length = 545
Score = 129 bits (311), Expect = 1e-29
Identities = 62/124 (50%), Positives = 85/124 (68%)
Frame = +1
Query: 373 YEDAVRKLNRLQSNKSTIEQIRKDIRTGQKCTNLEDMENYLSRTGVTMSKLDELSVVHVA 552
Y+DAVR LN LQ+N +EQ+++ + G T LE ME YL+R+G+ + LD L+++HV
Sbjct: 3 YQDAVRMLNTLQTNAGYLEQVKR--QRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVT 60
Query: 553 GTKGKGSTSAMCESILRHHGFRTGFYSSPHLXAVRXRVRLXXRVISEXMFAXYFHXVHXR 732
GTKGKGST A E ILR +G +TGF+SSPHL VR R+R+ + IS +F YF ++ R
Sbjct: 61 GTKGKGSTCAFTECILRSYGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHR 120
Query: 733 LEXT 744
LE T
Sbjct: 121 LEET 124
>BC064393-1|AAH64393.1| 587|Homo sapiens folylpolyglutamate
synthase protein.
Length = 587
Score = 129 bits (311), Expect = 1e-29
Identities = 62/124 (50%), Positives = 85/124 (68%)
Frame = +1
Query: 373 YEDAVRKLNRLQSNKSTIEQIRKDIRTGQKCTNLEDMENYLSRTGVTMSKLDELSVVHVA 552
Y+DAVR LN LQ+N +EQ+++ + G T LE ME YL+R+G+ + LD L+++HV
Sbjct: 45 YQDAVRMLNTLQTNAGYLEQVKR--QRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVT 102
Query: 553 GTKGKGSTSAMCESILRHHGFRTGFYSSPHLXAVRXRVRLXXRVISEXMFAXYFHXVHXR 732
GTKGKGST A E ILR +G +TGF+SSPHL VR R+R+ + IS +F YF ++ R
Sbjct: 103 GTKGKGSTCAFTECILRSYGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHR 162
Query: 733 LEXT 744
LE T
Sbjct: 163 LEET 166
>AL162586-11|CAI39770.1| 587|Homo sapiens folylpolyglutamate
synthase protein.
Length = 587
Score = 129 bits (311), Expect = 1e-29
Identities = 62/124 (50%), Positives = 85/124 (68%)
Frame = +1
Query: 373 YEDAVRKLNRLQSNKSTIEQIRKDIRTGQKCTNLEDMENYLSRTGVTMSKLDELSVVHVA 552
Y+DAVR LN LQ+N +EQ+++ + G T LE ME YL+R+G+ + LD L+++HV
Sbjct: 45 YQDAVRMLNTLQTNAGYLEQVKR--QRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVT 102
Query: 553 GTKGKGSTSAMCESILRHHGFRTGFYSSPHLXAVRXRVRLXXRVISEXMFAXYFHXVHXR 732
GTKGKGST A E ILR +G +TGF+SSPHL VR R+R+ + IS +F YF ++ R
Sbjct: 103 GTKGKGSTCAFTECILRSYGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHR 162
Query: 733 LEXT 744
LE T
Sbjct: 163 LEET 166
>AL162586-10|CAI39769.1| 375|Homo sapiens folylpolyglutamate
synthase protein.
Length = 375
Score = 129 bits (311), Expect = 1e-29
Identities = 62/124 (50%), Positives = 85/124 (68%)
Frame = +1
Query: 373 YEDAVRKLNRLQSNKSTIEQIRKDIRTGQKCTNLEDMENYLSRTGVTMSKLDELSVVHVA 552
Y+DAVR LN LQ+N +EQ+++ + G T LE ME YL+R+G+ + LD L+++HV
Sbjct: 45 YQDAVRMLNTLQTNAGYLEQVKR--QRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVT 102
Query: 553 GTKGKGSTSAMCESILRHHGFRTGFYSSPHLXAVRXRVRLXXRVISEXMFAXYFHXVHXR 732
GTKGKGST A E ILR +G +TGF+SSPHL VR R+R+ + IS +F YF ++ R
Sbjct: 103 GTKGKGSTCAFTECILRSYGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHR 162
Query: 733 LEXT 744
LE T
Sbjct: 163 LEET 166
>AL162586-14|CAI39773.1| 537|Homo sapiens folylpolyglutamate
synthase protein.
Length = 537
Score = 118 bits (284), Expect = 3e-26
Identities = 57/117 (48%), Positives = 79/117 (67%)
Frame = +1
Query: 394 LNRLQSNKSTIEQIRKDIRTGQKCTNLEDMENYLSRTGVTMSKLDELSVVHVAGTKGKGS 573
LN LQ+N +EQ+++ + G T LE ME YL+R+G+ + LD L+++HV GTKGKGS
Sbjct: 2 LNTLQTNAGYLEQVKR--QRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGS 59
Query: 574 TSAMCESILRHHGFRTGFYSSPHLXAVRXRVRLXXRVISEXMFAXYFHXVHXRLEXT 744
T A E ILR +G +TGF+SSPHL VR R+R+ + IS +F YF ++ RLE T
Sbjct: 60 TCAFTECILRSYGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHRLEET 116
>AL162586-13|CAI39772.1| 265|Homo sapiens folylpolyglutamate
synthase protein.
Length = 265
Score = 118 bits (284), Expect = 3e-26
Identities = 57/117 (48%), Positives = 79/117 (67%)
Frame = +1
Query: 394 LNRLQSNKSTIEQIRKDIRTGQKCTNLEDMENYLSRTGVTMSKLDELSVVHVAGTKGKGS 573
LN LQ+N +EQ+++ + G T LE ME YL+R+G+ + LD L+++HV GTKGKGS
Sbjct: 2 LNTLQTNAGYLEQVKR--QRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGS 59
Query: 574 TSAMCESILRHHGFRTGFYSSPHLXAVRXRVRLXXRVISEXMFAXYFHXVHXRLEXT 744
T A E ILR +G +TGF+SSPHL VR R+R+ + IS +F YF ++ RLE T
Sbjct: 60 TCAFTECILRSYGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHRLEET 116
>AL162586-12|CAI39771.1| 194|Homo sapiens folylpolyglutamate
synthase protein.
Length = 194
Score = 118 bits (284), Expect = 3e-26
Identities = 57/117 (48%), Positives = 79/117 (67%)
Frame = +1
Query: 394 LNRLQSNKSTIEQIRKDIRTGQKCTNLEDMENYLSRTGVTMSKLDELSVVHVAGTKGKGS 573
LN LQ+N +EQ+++ + G T LE ME YL+R+G+ + LD L+++HV GTKGKGS
Sbjct: 2 LNTLQTNAGYLEQVKR--QRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGS 59
Query: 574 TSAMCESILRHHGFRTGFYSSPHLXAVRXRVRLXXRVISEXMFAXYFHXVHXRLEXT 744
T A E ILR +G +TGF+SSPHL VR R+R+ + IS +F YF ++ RLE T
Sbjct: 60 TCAFTECILRSYGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHRLEET 116
>BT006639-1|AAP35285.1| 174|Homo sapiens folylpolyglutamate
synthase protein.
Length = 174
Score = 93.9 bits (223), Expect = 7e-19
Identities = 44/86 (51%), Positives = 61/86 (70%)
Frame = +1
Query: 373 YEDAVRKLNRLQSNKSTIEQIRKDIRTGQKCTNLEDMENYLSRTGVTMSKLDELSVVHVA 552
Y+DAVR LN LQ+N +EQ+++ + G T LE ME YL+R+G+ + LD L+++HV
Sbjct: 45 YQDAVRMLNTLQTNAGYLEQVKR--QRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVT 102
Query: 553 GTKGKGSTSAMCESILRHHGFRTGFY 630
GTKGKGST A E ILR +G +TGF+
Sbjct: 103 GTKGKGSTCAFTECILRSYGLKTGFF 128
>U40868-1|AAA87568.1| 486|Homo sapiens folylpolyglutamate
synthetase protein.
Length = 486
Score = 75.8 bits (178), Expect = 2e-13
Identities = 35/64 (54%), Positives = 44/64 (68%)
Frame = +1
Query: 553 GTKGKGSTSAMCESILRHHGFRTGFYSSPHLXAVRXRVRLXXRVISEXMFAXYFHXVHXR 732
GTKGKGST A E ILR +G +TGF+SSPHL VR R+R+ + IS +F YF ++ R
Sbjct: 2 GTKGKGSTCAFTECILRSYGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHR 61
Query: 733 LEXT 744
LE T
Sbjct: 62 LEET 65
>U14939-1|AAA85815.1| 107|Homo sapiens folylpolyglutamate
synthetase protein.
Length = 107
Score = 68.5 bits (160), Expect = 3e-11
Identities = 32/65 (49%), Positives = 46/65 (70%)
Frame = +1
Query: 373 YEDAVRKLNRLQSNKSTIEQIRKDIRTGQKCTNLEDMENYLSRTGVTMSKLDELSVVHVA 552
Y+DAVR LN LQ+N +EQ+++ + G T LE ME YL+R+G+ + LD L+++HV
Sbjct: 45 YQDAVRMLNTLQTNAGYLEQVKR--QRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVT 102
Query: 553 GTKGK 567
GTKGK
Sbjct: 103 GTKGK 107
>AY007211-2|AAL08406.1| 53|Homo sapiens folylpolyglutamate
synthetase cytosolic isoform protein.
Length = 53
Score = 35.9 bits (79), Expect = 0.19
Identities = 18/40 (45%), Positives = 26/40 (65%)
Frame = +1
Query: 373 YEDAVRKLNRLQSNKSTIEQIRKDIRTGQKCTNLEDMENY 492
++DAVR LN LQ+N +EQ+++ + G T LE ME Y
Sbjct: 16 FQDAVRMLNTLQTNAGYLEQVKR--QRGDPQTQLEAMELY 53
>AY007211-1|AAL08407.1| 75|Homo sapiens folylpolyglutamate
synthetase mitochondrial isoform protein.
Length = 75
Score = 35.9 bits (79), Expect = 0.19
Identities = 18/40 (45%), Positives = 26/40 (65%)
Frame = +1
Query: 373 YEDAVRKLNRLQSNKSTIEQIRKDIRTGQKCTNLEDMENY 492
++DAVR LN LQ+N +EQ+++ + G T LE ME Y
Sbjct: 38 FQDAVRMLNTLQTNAGYLEQVKR--QRGDPQTQLEAMELY 75
>AB030241-1|BAB39849.1| 521|Homo sapiens DRCTNNB1A protein.
Length = 521
Score = 30.7 bits (66), Expect = 7.1
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 2/60 (3%)
Frame = +1
Query: 469 NLE--DMENYLSRTGVTMSKLDELSVVHVAGTKGKGSTSAMCESILRHHGFRTGFYSSPH 642
NLE D + + T+ L + SV H + G + A+ ES L HG YS PH
Sbjct: 110 NLEIVDKQGHTKVLSFTIPSLSKPSVYHEPSSIG---SMALTESALSQHGLSKAVYSGPH 166
>U88528-1|AAC04325.1| 395|Homo sapiens transcription factor LZIP
protein.
Length = 395
Score = 30.3 bits (65), Expect = 9.4
Identities = 16/58 (27%), Positives = 25/58 (43%)
Frame = -3
Query: 688 R*PVXXSVPVXEQPXDAVTNRTLCGNRGDGVLIRTSHSLNPCLWFQQHEPQIARPTLT 515
R P+ ++P+ E P D + LC + S NPCL H + R T++
Sbjct: 32 RAPLDWALPLSEVPSDWEVDDLLCSLLSPPASLNILSSSNPCLVHHDHTYSLPRETVS 89
>U59629-1|AAD09210.1| 371|Homo sapiens transcription factor
LZIP-alpha protein.
Length = 371
Score = 30.3 bits (65), Expect = 9.4
Identities = 16/58 (27%), Positives = 25/58 (43%)
Frame = -3
Query: 688 R*PVXXSVPVXEQPXDAVTNRTLCGNRGDGVLIRTSHSLNPCLWFQQHEPQIARPTLT 515
R P+ ++P+ E P D + LC + S NPCL H + R T++
Sbjct: 32 RAPLDWALPLSEVPSDWEVDDLLCSLLSPPASLNILSSSNPCLVHHDHTYSLPRETVS 89
>BC010158-1|AAH10158.1| 371|Homo sapiens cAMP responsive element
binding protein 3 protein.
Length = 371
Score = 30.3 bits (65), Expect = 9.4
Identities = 16/58 (27%), Positives = 25/58 (43%)
Frame = -3
Query: 688 R*PVXXSVPVXEQPXDAVTNRTLCGNRGDGVLIRTSHSLNPCLWFQQHEPQIARPTLT 515
R P+ ++P+ E P D + LC + S NPCL H + R T++
Sbjct: 32 RAPLDWALPLSEVPSDWEVDDLLCSLLSPPASLNILSSSNPCLVHHDHTYSLPRETVS 89
>BC009402-1|AAH09402.1| 371|Homo sapiens cAMP responsive element
binding protein 3 protein.
Length = 371
Score = 30.3 bits (65), Expect = 9.4
Identities = 16/58 (27%), Positives = 25/58 (43%)
Frame = -3
Query: 688 R*PVXXSVPVXEQPXDAVTNRTLCGNRGDGVLIRTSHSLNPCLWFQQHEPQIARPTLT 515
R P+ ++P+ E P D + LC + S NPCL H + R T++
Sbjct: 32 RAPLDWALPLSEVPSDWEVDDLLCSLLSPPASLNILSSSNPCLVHHDHTYSLPRETVS 89
>AL133410-7|CAI10980.1| 371|Homo sapiens cAMP responsive element
binding protein 3 protein.
Length = 371
Score = 30.3 bits (65), Expect = 9.4
Identities = 16/58 (27%), Positives = 25/58 (43%)
Frame = -3
Query: 688 R*PVXXSVPVXEQPXDAVTNRTLCGNRGDGVLIRTSHSLNPCLWFQQHEPQIARPTLT 515
R P+ ++P+ E P D + LC + S NPCL H + R T++
Sbjct: 32 RAPLDWALPLSEVPSDWEVDDLLCSLLSPPASLNILSSSNPCLVHHDHTYSLPRETVS 89
>AF211848-1|AAG43528.1| 371|Homo sapiens cAMP responsive element
binding protein 3 protein.
Length = 371
Score = 30.3 bits (65), Expect = 9.4
Identities = 16/58 (27%), Positives = 25/58 (43%)
Frame = -3
Query: 688 R*PVXXSVPVXEQPXDAVTNRTLCGNRGDGVLIRTSHSLNPCLWFQQHEPQIARPTLT 515
R P+ ++P+ E P D + LC + S NPCL H + R T++
Sbjct: 32 RAPLDWALPLSEVPSDWEVDDLLCSLLSPPASLNILSSSNPCLVHHDHTYSLPRETVS 89
>AF211847-1|AAG43527.1| 371|Homo sapiens cAMP responsive element
binding protein 3 protein.
Length = 371
Score = 30.3 bits (65), Expect = 9.4
Identities = 16/58 (27%), Positives = 25/58 (43%)
Frame = -3
Query: 688 R*PVXXSVPVXEQPXDAVTNRTLCGNRGDGVLIRTSHSLNPCLWFQQHEPQIARPTLT 515
R P+ ++P+ E P D + LC + S NPCL H + R T++
Sbjct: 32 RAPLDWALPLSEVPSDWEVDDLLCSLLSPPASLNILSSSNPCLVHHDHTYSLPRETVS 89
>AF029674-1|AAB84166.1| 371|Homo sapiens basic leucine zipper
protein LZIP protein.
Length = 371
Score = 30.3 bits (65), Expect = 9.4
Identities = 16/58 (27%), Positives = 25/58 (43%)
Frame = -3
Query: 688 R*PVXXSVPVXEQPXDAVTNRTLCGNRGDGVLIRTSHSLNPCLWFQQHEPQIARPTLT 515
R P+ ++P+ E P D + LC + S NPCL H + R T++
Sbjct: 32 RAPLDWALPLSEVPSDWEVDDLLCSLLSPPASLNILSSSNPCLVHHDHTYSLPRETVS 89
>AF009368-1|AAB69652.1| 371|Homo sapiens Luman protein.
Length = 371
Score = 30.3 bits (65), Expect = 9.4
Identities = 16/58 (27%), Positives = 25/58 (43%)
Frame = -3
Query: 688 R*PVXXSVPVXEQPXDAVTNRTLCGNRGDGVLIRTSHSLNPCLWFQQHEPQIARPTLT 515
R P+ ++P+ E P D + LC + S NPCL H + R T++
Sbjct: 32 RAPLDWALPLSEVPSDWEVDDLLCSLLSPPASLNILSSSNPCLVHHDHTYSLPRETVS 89
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 89,830,806
Number of Sequences: 237096
Number of extensions: 1616467
Number of successful extensions: 2898
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 2803
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2888
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10928473528
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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