Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP11_F_E02
(850 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_A7UBP6 Cluster: Putative 3-hydroxyisobutyrate dehydroge... 155 1e-36
UniRef50_Q7NWA9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 155 2e-36
UniRef50_Q54CX6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 151 3e-35
UniRef50_UPI0000D56743 Cluster: PREDICTED: similar to 3-hydroxyi... 146 8e-34
UniRef50_A7JGH8 Cluster: Predicted protein; n=1; Francisella tul... 144 3e-33
UniRef50_P28811 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 142 1e-32
UniRef50_A1QPH6 Cluster: 3-hydroxyisobutyrate dehydrogenase mmsB... 136 9e-31
UniRef50_P63936 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 136 9e-31
UniRef50_A0UF54 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 134 2e-30
UniRef50_Q399N0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 133 5e-30
UniRef50_P31937 Cluster: 3-hydroxyisobutyrate dehydrogenase, mit... 132 8e-30
UniRef50_A0QSJ0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 130 3e-29
UniRef50_Q0K0E2 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1... 128 2e-28
UniRef50_A0JUJ6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 128 2e-28
UniRef50_Q9K9L1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 126 5e-28
UniRef50_Q0SBQ9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 126 9e-28
UniRef50_Q55702 Cluster: Uncharacterized oxidoreductase slr0229;... 126 9e-28
UniRef50_Q83D20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9... 125 2e-27
UniRef50_Q9V8M5 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 124 2e-27
UniRef50_Q8ES28 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 124 3e-27
UniRef50_A3I4V2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 124 3e-27
UniRef50_Q4FMJ3 Cluster: 6-phosphogluconate dehydrogenase; n=2; ... 123 5e-27
UniRef50_A5V0D4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 122 9e-27
UniRef50_A6NVP0 Cluster: Putative uncharacterized protein; n=1; ... 122 1e-26
UniRef50_Q1AVA4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 121 3e-26
UniRef50_Q1V2R0 Cluster: MmsB-like protein; n=2; Candidatus Pela... 120 5e-26
UniRef50_Q8KL12 Cluster: Probable 6-phosphogluconate dehydrogena... 120 6e-26
UniRef50_Q4ZQL5 Cluster: 3-hydroxyisobutyrate dehydrogenase prec... 119 1e-25
UniRef50_Q22B54 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 119 1e-25
UniRef50_Q11FC5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 118 2e-25
UniRef50_Q9A8J9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 117 3e-25
UniRef50_Q1QWU9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 117 3e-25
UniRef50_Q0QLF5 Cluster: 2-hydroxymethyl glutarate dehydrogenase... 116 6e-25
UniRef50_A4IN46 Cluster: 3-hydroxyisobutyrate dehydrogenase-like... 116 6e-25
UniRef50_O34948 Cluster: Uncharacterized oxidoreductase ykwC; n=... 116 6e-25
UniRef50_Q41DK0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 115 1e-24
UniRef50_A3RRS1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 114 2e-24
UniRef50_Q930C6 Cluster: Probable; n=8; Alphaproteobacteria|Rep:... 113 4e-24
UniRef50_A6P2M7 Cluster: Putative uncharacterized protein; n=2; ... 113 5e-24
UniRef50_A2SP40 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 113 5e-24
UniRef50_Q9SUC0 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 113 5e-24
UniRef50_A1SIN3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 113 7e-24
UniRef50_Q97XZ7 Cluster: Oxidoreductase; n=6; Thermoprotei|Rep: ... 113 7e-24
UniRef50_Q58PL4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 112 9e-24
UniRef50_Q67QX0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 112 1e-23
UniRef50_Q183P5 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 111 2e-23
UniRef50_A6SW62 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 111 3e-23
UniRef50_A3SJ77 Cluster: Probable oxidoreductase; n=1; Roseovari... 110 5e-23
UniRef50_Q1QWQ5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 109 1e-22
UniRef50_P0ABQ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 108 2e-22
UniRef50_A6LT11 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 108 2e-22
UniRef50_Q01ZG6 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 107 3e-22
UniRef50_Q92D17 Cluster: Lin1004 protein; n=10; Bacilli|Rep: Lin... 106 6e-22
UniRef50_A0GVR3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 106 8e-22
UniRef50_A0K0Z6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 105 2e-21
UniRef50_UPI00015B4162 Cluster: PREDICTED: similar to MGC108315 ... 104 2e-21
UniRef50_Q12CU4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 104 2e-21
UniRef50_Q0S5S3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 103 4e-21
UniRef50_Q03UI4 Cluster: 3-hydroxyisobutyrate dehydrogenase rela... 103 4e-21
UniRef50_Q5WBB8 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 102 1e-20
UniRef50_A6GTB5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 102 1e-20
UniRef50_Q2JEV5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 101 2e-20
UniRef50_Q1GJB9 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 101 2e-20
UniRef50_A1UP64 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 101 2e-20
UniRef50_Q7WCG3 Cluster: Putative uncharacterized protein; n=2; ... 101 3e-20
UniRef50_A0LTQ8 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 101 3e-20
UniRef50_Q4Q7T9 Cluster: 2-hydroxy-3-oxopropionate reductase, pu... 100 4e-20
UniRef50_Q5L168 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 99 7e-20
UniRef50_Q1YHQ4 Cluster: Putative 2-hydroxy-3-oxopropionate redu... 99 7e-20
UniRef50_A0C2T7 Cluster: Chromosome undetermined scaffold_145, w... 99 7e-20
UniRef50_Q9L7S0 Cluster: Uncharacterized oxidoreductase yihU; n=... 99 7e-20
UniRef50_Q4KH51 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 100 9e-20
UniRef50_A0N0V2 Cluster: BtdhL; n=1; Azoarcus anaerobius|Rep: Bt... 100 9e-20
UniRef50_A0LMG6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9... 100 9e-20
UniRef50_A2U9T6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 99 1e-19
UniRef50_Q7WG50 Cluster: Probable oxidoreductase; n=1; Bordetell... 99 2e-19
UniRef50_A3VLN6 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 99 2e-19
UniRef50_Q89HA0 Cluster: Oxidoreductase; n=1; Bradyrhizobium jap... 98 3e-19
UniRef50_Q94B07 Cluster: Gamma hydroxybutyrate dehydrogenase; n=... 97 4e-19
UniRef50_Q89R44 Cluster: Oxidoreductase; n=23; Bacteria|Rep: Oxi... 97 5e-19
UniRef50_A5USN9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 97 5e-19
UniRef50_A1B741 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 97 5e-19
UniRef50_Q89UN2 Cluster: Bll1384 protein; n=9; Bacteria|Rep: Bll... 96 9e-19
UniRef50_A6SUL3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 96 9e-19
UniRef50_Q0F1Y7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 96 1e-18
UniRef50_Q84VC8 Cluster: Gamma hydroxybutyrate dehydrogenase-lik... 95 2e-18
UniRef50_A3WAC4 Cluster: Dehydrogenase; n=4; Bacteria|Rep: Dehyd... 94 5e-18
UniRef50_Q0LNZ7 Cluster: 3-hydroxyisobutyrate dehydrogenase prec... 93 8e-18
UniRef50_Q18X68 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 93 1e-17
UniRef50_A5VEA3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 93 1e-17
UniRef50_A5GPC0 Cluster: Hydroxyacid dehydrogenase/reductase fam... 93 1e-17
UniRef50_A0G5G5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 93 1e-17
UniRef50_Q47AR2 Cluster: NADP oxidoreductase, coenzyme F420-depe... 92 1e-17
UniRef50_A3K497 Cluster: Probable 6-phosphogluconate dehydrogena... 92 1e-17
UniRef50_Q3DYV4 Cluster: NADP oxidoreductase, coenzyme F420-depe... 92 2e-17
UniRef50_Q84H84 Cluster: Putative oxidoreductase; n=1; Arthrobac... 91 2e-17
UniRef50_Q01QM2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 91 2e-17
UniRef50_A0FZ96 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 91 3e-17
UniRef50_Q8UBW3 Cluster: Oxidoredutase; n=1; Agrobacterium tumef... 91 4e-17
UniRef50_A5VBF0 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 91 4e-17
UniRef50_A0JXR2 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 91 4e-17
UniRef50_A3X9R7 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 90 6e-17
UniRef50_A6EH53 Cluster: Putative uncharacterized protein; n=1; ... 89 1e-16
UniRef50_Q1IQE6 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 89 1e-16
UniRef50_A1ZWM5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 89 1e-16
UniRef50_A1R2J4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 89 1e-16
UniRef50_Q606G9 Cluster: Oxidoreductase, Gfo/Idh/MocA family; n=... 89 2e-16
UniRef50_Q0RCX7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 89 2e-16
UniRef50_A7IE35 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 89 2e-16
UniRef50_A5P0V0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 89 2e-16
UniRef50_Q39FA8 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 88 2e-16
UniRef50_A7PEG7 Cluster: Chromosome chr11 scaffold_13, whole gen... 88 3e-16
UniRef50_Q8TT25 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 88 3e-16
UniRef50_A3H5R1 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 88 3e-16
UniRef50_Q89M84 Cluster: Blr4309 protein; n=6; Bradyrhizobiaceae... 87 5e-16
UniRef50_Q39MY1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 87 5e-16
UniRef50_A0QUD5 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 86 9e-16
UniRef50_Q656T5 Cluster: Oxidoreductase-like; n=3; Oryza sativa|... 86 9e-16
UniRef50_A3JU55 Cluster: Predicted dehydrogenase, with NAD(P)-bi... 86 1e-15
UniRef50_Q1N6I0 Cluster: Putative oxidoreductase protein; n=1; O... 85 2e-15
UniRef50_Q1B326 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 85 2e-15
UniRef50_A3WMG5 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 85 2e-15
UniRef50_A1UJF2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 85 2e-15
UniRef50_A0NRG5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 85 2e-15
UniRef50_Q4PCH4 Cluster: Putative uncharacterized protein; n=1; ... 85 2e-15
UniRef50_Q8EW87 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 85 3e-15
UniRef50_Q7NR40 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 85 3e-15
UniRef50_Q49A26 Cluster: Cytokine-like nuclear factor n-pac; n=4... 84 4e-15
UniRef50_A7DSF1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 84 4e-15
UniRef50_Q13LQ9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 84 5e-15
UniRef50_Q3W9L4 Cluster: Putative uncharacterized protein; n=1; ... 83 6e-15
UniRef50_A5FTT0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 83 6e-15
UniRef50_A0R1N4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 83 9e-15
UniRef50_Q98I20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 83 1e-14
UniRef50_Q73P00 Cluster: 3-hydroxyacid dehydrogenase family prot... 83 1e-14
UniRef50_A0G5F9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 83 1e-14
UniRef50_Q1GF31 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 82 1e-14
UniRef50_A0LDJ3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 82 2e-14
UniRef50_Q0FFH2 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 81 3e-14
UniRef50_A0GPK7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 81 3e-14
UniRef50_Q4WV01 Cluster: Oxidoreductase, acting on the CH-OH gro... 81 3e-14
UniRef50_O33730 Cluster: Uncharacterized oxidoreductase Sfri_150... 81 3e-14
UniRef50_Q830A7 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 81 3e-14
UniRef50_Q5LQR0 Cluster: 6-phosphogluconate dehydrogenase domain... 81 3e-14
UniRef50_Q8VYC5 Cluster: Fructose-bisphosphate aldolase; n=12; c... 80 6e-14
UniRef50_Q0URA2 Cluster: Putative uncharacterized protein; n=1; ... 80 6e-14
UniRef50_A1CAY2 Cluster: Oxidoreductase, acting on the CH-OH gro... 80 6e-14
UniRef50_A4SWE8 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 80 8e-14
UniRef50_Q89RT2 Cluster: Bll2680 protein; n=1; Bradyrhizobium ja... 79 1e-13
UniRef50_Q3W3N3 Cluster: Putative uncharacterized protein; n=1; ... 79 1e-13
UniRef50_A6VLT0 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 79 1e-13
UniRef50_Q019Z7 Cluster: Oxidoreductase-like; n=1; Ostreococcus ... 79 1e-13
UniRef50_Q6C351 Cluster: Yarrowia lipolytica chromosome F of str... 79 1e-13
UniRef50_A1WM48 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 79 1e-13
UniRef50_P77161 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 79 1e-13
UniRef50_Q5FQ06 Cluster: Putative oxidoreductase; n=1; Gluconoba... 79 2e-13
UniRef50_A6F020 Cluster: Putative uncharacterized protein; n=1; ... 79 2e-13
UniRef50_Q13PY3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 78 2e-13
UniRef50_A6G049 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 78 3e-13
UniRef50_Q2UHA9 Cluster: Predicted dehydrogenase; n=16; Pezizomy... 77 6e-13
UniRef50_Q121N3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 77 7e-13
UniRef50_A3EW86 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 76 1e-12
UniRef50_Q9JYH6 Cluster: 3-hydroxyacid dehydrogenase; n=5; Prote... 76 1e-12
UniRef50_Q2CHC8 Cluster: Oxidoreductase; n=1; Oceanicola granulo... 76 1e-12
UniRef50_A6VYD9 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 76 1e-12
UniRef50_Q6UCZ9 Cluster: Predicted oxidoreductase; n=2; environm... 75 2e-12
UniRef50_Q2BFK1 Cluster: Oxidoreductase; n=1; Bacillus sp. NRRL ... 75 2e-12
UniRef50_Q0UVR9 Cluster: Putative uncharacterized protein; n=1; ... 75 2e-12
UniRef50_Q0KC92 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1... 75 3e-12
UniRef50_UPI0001597301 Cluster: YfjR; n=1; Bacillus amyloliquefa... 74 4e-12
UniRef50_A1WJN2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 74 4e-12
UniRef50_A1GFG2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 74 4e-12
UniRef50_Q7WNK6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 74 5e-12
UniRef50_Q1EPJ1 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 74 5e-12
UniRef50_Q8PK98 Cluster: 3-hydroxyisobutirate dehydrogenase; n=3... 73 7e-12
UniRef50_Q12H32 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 73 7e-12
UniRef50_Q55JR1 Cluster: Putative uncharacterized protein; n=2; ... 73 9e-12
UniRef50_O66454 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 73 1e-11
UniRef50_Q3WJ00 Cluster: 6-phosphogluconate dehydrogenase, NAD b... 73 1e-11
UniRef50_Q20XN2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 73 1e-11
UniRef50_A2C1U6 Cluster: 3-hydroxyisobutyrate dehydrogenase and ... 73 1e-11
UniRef50_Q7VYY0 Cluster: Putative oxidoreductase; n=4; Bordetell... 72 2e-11
UniRef50_A4ECY9 Cluster: Putative uncharacterized protein; n=1; ... 72 2e-11
UniRef50_Q9LNP0 Cluster: F1L3.35; n=8; Magnoliophyta|Rep: F1L3.3... 72 2e-11
UniRef50_Q3W9W7 Cluster: 6-phosphogluconate dehydrogenase, NAD b... 72 2e-11
UniRef50_A7H7Z5 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 72 2e-11
UniRef50_Q98K09 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 71 3e-11
UniRef50_Q46TQ0 Cluster: UDP-glucose/GDP-mannose dehydrogenase:P... 71 3e-11
UniRef50_Q9LM23 Cluster: Fructose-bisphosphate aldolase; n=2; Ar... 71 3e-11
UniRef50_Q74D68 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 71 4e-11
UniRef50_A3LTC4 Cluster: 3-hydroxyisobutyrate dehydrogenase-like... 71 4e-11
UniRef50_A3H9B3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 71 4e-11
UniRef50_P71825 Cluster: Uncharacterized oxidoreductase Rv0770/M... 71 4e-11
UniRef50_A0R1N5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 71 5e-11
UniRef50_Q9HLR4 Cluster: Putative uncharacterized protein Ta0161... 70 9e-11
UniRef50_Q5LNV6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 69 1e-10
UniRef50_A1UJF3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 69 1e-10
UniRef50_A7RG59 Cluster: Predicted protein; n=1; Nematostella ve... 69 1e-10
UniRef50_Q39KK8 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 68 3e-10
UniRef50_A5WG80 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 68 3e-10
UniRef50_Q4Q9Z1 Cluster: Dehydrogenase-like protein; n=6; Trypan... 68 3e-10
UniRef50_Q0RIL5 Cluster: Putative uncharacterized protein; n=1; ... 68 3e-10
UniRef50_Q033P2 Cluster: 3-hydroxyisobutyrate dehydrogenase rela... 68 3e-10
UniRef50_A0JRK4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 68 3e-10
UniRef50_A0RU56 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 68 3e-10
UniRef50_Q7NEW9 Cluster: Glr3759 protein; n=3; Bacteria|Rep: Glr... 67 5e-10
UniRef50_Q0BTJ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 67 5e-10
UniRef50_A0YMN9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 67 5e-10
UniRef50_Q120Q9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 67 6e-10
UniRef50_Q9RX16 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=6... 66 1e-09
UniRef50_Q21ZN3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 66 1e-09
UniRef50_A3Y8R5 Cluster: Putative dehydrogenase; n=1; Marinomona... 66 1e-09
UniRef50_Q8F4I7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4... 66 1e-09
UniRef50_Q9I1R8 Cluster: Probable dehydrogenase; n=7; Pseudomona... 65 2e-09
UniRef50_A0GI22 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 65 2e-09
UniRef50_Q0C8I2 Cluster: Predicted protein; n=3; Pezizomycotina|... 65 2e-09
UniRef50_A6RMW8 Cluster: Putative uncharacterized protein; n=2; ... 65 2e-09
UniRef50_A6R0U9 Cluster: Predicted protein; n=1; Ajellomyces cap... 65 2e-09
UniRef50_A7DWL2 Cluster: Putative dehydrogenase; n=1; Streptomyc... 64 3e-09
UniRef50_A5P600 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 64 3e-09
UniRef50_Q6F842 Cluster: Putative 3-hydroxyisobutyrate dehydroge... 64 4e-09
UniRef50_Q1V2K7 Cluster: NADP oxidoreductase, coenzyme F420-depe... 64 4e-09
UniRef50_Q221W9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 64 6e-09
UniRef50_Q392H4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 63 7e-09
UniRef50_Q2JEN4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 63 7e-09
UniRef50_A0AWL7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 63 7e-09
UniRef50_Q82ZC2 Cluster: 6-phosphogluconate dehydrogenase family... 63 1e-08
UniRef50_A1UDJ6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 63 1e-08
UniRef50_Q21ZT0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 62 2e-08
UniRef50_A1SQ87 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 62 2e-08
UniRef50_Q5GUM4 Cluster: Dehydrogenase; n=5; Gammaproteobacteria... 61 4e-08
UniRef50_A3ES45 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 60 5e-08
UniRef50_Q7Q161 Cluster: ENSANGP00000013149; n=11; Culicidae|Rep... 60 5e-08
UniRef50_Q6RXW5 Cluster: Succinic semialdehyde dehydrogenase; n=... 60 7e-08
UniRef50_A0K107 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 60 9e-08
UniRef50_Q3W031 Cluster: Putative dehydrogenase; n=1; Frankia sp... 59 2e-07
UniRef50_A3ET09 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 59 2e-07
UniRef50_Q0SAG5 Cluster: Phosphogluconate dehydrogenase; n=23; A... 58 2e-07
UniRef50_A4FKN9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 58 2e-07
UniRef50_A3Q3U7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 58 2e-07
UniRef50_Q0W2D7 Cluster: Putative 6-phosphogluconate dehydrogena... 58 3e-07
UniRef50_Q01PV6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 57 5e-07
UniRef50_Q1GM24 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 57 6e-07
UniRef50_A5CN67 Cluster: Putative beta-hydroxyacid dehydrogenase... 57 6e-07
UniRef50_Q97ZE5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4... 57 6e-07
UniRef50_A4EEN1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 56 9e-07
UniRef50_A1WEB7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 56 9e-07
UniRef50_Q9RU02 Cluster: 6-phosphogluconate dehydrogenase; n=24;... 56 1e-06
UniRef50_Q89GM2 Cluster: Bll6323 protein; n=6; Proteobacteria|Re... 56 1e-06
UniRef50_Q4WXG9 Cluster: 3-hydroxyisobutyrate dehydrogenase, put... 56 1e-06
UniRef50_A3PRM1 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 56 1e-06
UniRef50_Q21AH6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 55 3e-06
UniRef50_A3PSD9 Cluster: 6-phosphogluconate dehydrogenase, decar... 55 3e-06
UniRef50_Q1INE9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 54 3e-06
UniRef50_Q92P61 Cluster: 6-phosphogluconate dehydrogenase, decar... 54 5e-06
UniRef50_Q8U2W2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 54 5e-06
UniRef50_Q8YRT5 Cluster: 3-hydroxyacid dehydrogenase; n=5; Cyano... 53 8e-06
UniRef50_O66788 Cluster: 6-phosphogluconate dehydrogenase; n=2; ... 53 8e-06
UniRef50_A5FVG0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 53 8e-06
UniRef50_A0VSV4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 53 1e-05
UniRef50_Q6KZX0 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 52 1e-05
UniRef50_Q3J9H5 Cluster: 6-phosphogluconate dehydrogenase, decar... 52 2e-05
UniRef50_Q13VQ8 Cluster: Putative dehydrogenase/oxidoreductase p... 52 2e-05
UniRef50_P80859 Cluster: 6-phosphogluconate dehydrogenase, decar... 52 2e-05
UniRef50_Q9K9H3 Cluster: 6-phosphogluconate dehydrogenase; n=7; ... 51 3e-05
UniRef50_Q1NHG5 Cluster: Putative uncharacterized protein; n=1; ... 51 3e-05
UniRef50_Q1NHF5 Cluster: Putative oxidoreductase; n=1; Sphingomo... 51 4e-05
UniRef50_Q19TN0 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 51 4e-05
UniRef50_Q0RMX6 Cluster: Putative reductase; n=1; Frankia alni A... 51 4e-05
UniRef50_Q4WSB8 Cluster: 6-phosphogluconate dehydrogenase family... 51 4e-05
UniRef50_Q5FHQ8 Cluster: 6-phosphogluconate dehydrogenase, decar... 50 7e-05
UniRef50_Q220G7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 50 7e-05
UniRef50_A6ELE2 Cluster: 6-phosphogluconate dehydrogenase, decar... 50 7e-05
UniRef50_Q9V8M5-2 Cluster: Isoform C of Q9V8M5 ; n=1; Drosophila... 50 1e-04
UniRef50_Q55W03 Cluster: Putative uncharacterized protein; n=2; ... 49 1e-04
UniRef50_A3H6C3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 49 2e-04
UniRef50_A4BV63 Cluster: 3-hydroxyacid dehydrogenase; n=1; Nitro... 48 2e-04
UniRef50_P54448 Cluster: Uncharacterized protein yqeC; n=13; Bac... 48 4e-04
UniRef50_P37754 Cluster: 6-phosphogluconate dehydrogenase, decar... 48 4e-04
UniRef50_Q64V77 Cluster: 6-phosphogluconate dehydrogenase, decar... 47 5e-04
UniRef50_Q0U6Q6 Cluster: Putative uncharacterized protein; n=5; ... 47 7e-04
UniRef50_Q5FU44 Cluster: Putative oxidoreductase; n=1; Gluconoba... 46 0.001
UniRef50_Q836Q9 Cluster: 6-phosphogluconate dehydrogenase, decar... 46 0.001
UniRef50_Q6D9X4 Cluster: Putative 2-hydroxy-3-oxopropionate redu... 46 0.001
UniRef50_Q660W3 Cluster: 6-phosphogluconate dehydrogenase, decar... 46 0.001
UniRef50_Q9RBX6 Cluster: IgiB; n=1; Vogesella indigofera|Rep: Ig... 46 0.001
UniRef50_A4S5A4 Cluster: Predicted protein; n=2; Ostreococcus|Re... 46 0.002
UniRef50_O34969 Cluster: Uncharacterized oxidoreductase yfjR; n=... 46 0.002
UniRef50_A2BJA4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 45 0.002
UniRef50_A0QZR7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 44 0.004
UniRef50_Q17761 Cluster: 6-phosphogluconate dehydrogenase, decar... 44 0.004
UniRef50_Q5MZU3 Cluster: 3-hydroxyacid dehydrogenase; n=3; Cyano... 44 0.005
UniRef50_A4JSC3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 44 0.005
UniRef50_Q8TUC1 Cluster: Predicted protein; n=4; Methanosarcinac... 44 0.005
UniRef50_A1RWA6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 44 0.005
UniRef50_Q2UET7 Cluster: Predicted protein; n=7; Eurotiomycetida... 43 0.011
UniRef50_Q629W3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 42 0.015
UniRef50_P21577 Cluster: 6-phosphogluconate dehydrogenase, decar... 42 0.015
UniRef50_Q7TZG1 Cluster: 6-phosphogluconate dehydrogenase, decar... 41 0.034
UniRef50_O32911 Cluster: 6-phosphogluconate dehydrogenase, decar... 41 0.034
UniRef50_P31072 Cluster: 6-phosphogluconate dehydrogenase, decar... 41 0.034
UniRef50_A7CWR7 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 41 0.045
UniRef50_A6T947 Cluster: Putative dehydrogenase; n=1; Klebsiella... 41 0.045
UniRef50_Q1AZK2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 40 0.079
UniRef50_A2Q7E9 Cluster: Function: mmsB of P. aeruginosa is invo... 40 0.079
UniRef50_Q9CDN4 Cluster: 6-phosphogluconate dehydrogenase; n=12;... 39 0.14
UniRef50_A5GJY3 Cluster: 3-hydroxyisobutyrate dehydrogenase rela... 39 0.14
UniRef50_A4ENK2 Cluster: 3-demethylubiquinone-9 3-methyltransfer... 39 0.18
UniRef50_A5K3L2 Cluster: 6-phosphogluconate dehydrogenase, decar... 39 0.18
UniRef50_Q9YE14 Cluster: Putative dehydrogenase; n=1; Aeropyrum ... 39 0.18
UniRef50_A0Y665 Cluster: 6-phosphogluconate dehydrogenase; n=3; ... 38 0.24
UniRef50_UPI0000EBE4FC Cluster: PREDICTED: hypothetical protein;... 38 0.32
UniRef50_Q9YFQ6 Cluster: L-lysine 6-dehydrogenase; n=1; Aeropyru... 38 0.32
UniRef50_A6RYG0 Cluster: Putative uncharacterized protein; n=1; ... 38 0.42
UniRef50_Q2LGT9 Cluster: 6-phosphogluconate dehydrogenase; n=6; ... 37 0.74
UniRef50_Q988C8 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1... 36 0.97
UniRef50_Q1YFU0 Cluster: Posibble methylase involved in ubiquino... 36 0.97
UniRef50_A0FZ97 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 36 0.97
UniRef50_A4ES45 Cluster: Methyltransferase type 11; n=1; Roseoba... 36 1.3
UniRef50_A4ARS6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 36 1.3
UniRef50_Q8SRX1 Cluster: 6-PHOSPHOGLUCONATE DEHYDROGENASE; n=1; ... 36 1.3
UniRef50_Q944B6 Cluster: Arogenate dehydrogenase 1, chloroplast ... 36 1.3
UniRef50_A6W129 Cluster: 6-phosphogluconate dehydrogenase, decar... 36 1.7
UniRef50_Q6N3Q8 Cluster: 6-phosphogluconate dehydrogenase; n=57;... 35 2.2
UniRef50_Q5PAV2 Cluster: 3-demethylubiquinone-9 3-methyltransfer... 35 2.2
UniRef50_Q1N6E5 Cluster: Erythronate-4-phosphate dehydrogenase; ... 35 2.2
UniRef50_A6VZU5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 35 2.2
UniRef50_A4SGI3 Cluster: NAD-dependent epimerase/dehydratase; n=... 35 2.2
UniRef50_A1U1I8 Cluster: Erythronate-4-phosphate dehydrogenase; ... 35 2.2
UniRef50_P41572 Cluster: 6-phosphogluconate dehydrogenase, decar... 35 2.2
UniRef50_UPI0000E46E06 Cluster: PREDICTED: similar to MGC107852 ... 35 3.0
UniRef50_Q2S7E0 Cluster: Phosphoglycerate dehydrogenase and rela... 35 3.0
UniRef50_A4XCN7 Cluster: Methyltransferase type 11; n=2; Salinis... 35 3.0
UniRef50_A3Y0Y8 Cluster: Putative tartronate semialdehyde reduct... 35 3.0
UniRef50_A3U721 Cluster: Putative uncharacterized protein; n=1; ... 35 3.0
UniRef50_UPI0000E221EA Cluster: PREDICTED: similar to NMDAR1 sub... 34 3.9
UniRef50_UPI000050FDFD Cluster: COG0569: K+ transport systems, N... 34 3.9
UniRef50_Q7WCB1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 34 3.9
UniRef50_Q3DWX0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 34 5.2
UniRef50_Q11JE9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 34 5.2
UniRef50_A6G079 Cluster: Leucine dehydrogenase; n=1; Plesiocysti... 34 5.2
UniRef50_UPI0000E8153F Cluster: PREDICTED: hypothetical protein;... 33 6.9
UniRef50_Q0S6F7 Cluster: 3-demethylubiquinone-9 3-O-methyltransf... 33 6.9
UniRef50_A0Z3U5 Cluster: Putative uncharacterized protein; n=1; ... 33 6.9
UniRef50_A7QQA4 Cluster: Chromosome undetermined scaffold_141, w... 33 6.9
UniRef50_Q0VQC3 Cluster: Erythronate-4-phosphate dehydrogenase; ... 33 6.9
UniRef50_Q88ZU6 Cluster: Phosphoglycerate dehydrogenase; n=2; La... 33 9.1
UniRef50_Q6F272 Cluster: 1-pyrroline-5-carboxylate reductase; n=... 33 9.1
UniRef50_O67636 Cluster: Prephenate dehydrogenase; n=1; Aquifex ... 33 9.1
UniRef50_Q9RQV3 Cluster: Putative prephenate dehydrogenase TyrC;... 33 9.1
UniRef50_Q2BJD5 Cluster: Probable UDP-glucose/GDP-mannose dehydr... 33 9.1
UniRef50_A6TCR4 Cluster: 2-ketoacid reductase; n=1; Klebsiella p... 33 9.1
UniRef50_A6NX21 Cluster: Putative uncharacterized protein; n=1; ... 33 9.1
UniRef50_A1FPN2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 33 9.1
UniRef50_A0Q3X1 Cluster: Putative uncharacterized protein; n=1; ... 33 9.1
UniRef50_A0GGU8 Cluster: Putative uncharacterized protein; n=1; ... 33 9.1
>UniRef50_A7UBP6 Cluster: Putative 3-hydroxyisobutyrate
dehydrogenase; n=1; Paracoccus methylutens|Rep: Putative
3-hydroxyisobutyrate dehydrogenase - Paracoccus
methylutens
Length = 302
Score = 155 bits (377), Expect = 1e-36
Identities = 81/184 (44%), Positives = 108/184 (58%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
V FLGLG MG MA NL G V YDPS++ AAK G+ A+ + +
Sbjct: 4 VGFLGLGRMGFPMARNLATAGHDVHVYDPSEEVGRKAAKAGLKTASRVDVAVEGADFVIT 63
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
++ + + VL+++LG DGV+A KGS+ IDSSTID +++ E+G+ DAPVSG
Sbjct: 64 MVPTGRHVLEIFLGDDGVLAKMAKGSMAIDSSTIDTADARRLHAAGRERGIAVLDAPVSG 123
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPRL 726
GVMGA TL FM GG ED ER+ P+L MG + FH G+ G G AKL NN L G +
Sbjct: 124 GVMGAEAGTLTFMVGGSAEDLERARPVLEAMGRRIFHAGEPGVGQAAKLCNNLLAGISMI 183
Query: 727 AXAD 738
A ++
Sbjct: 184 AVSE 187
>UniRef50_Q7NWA9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Chromobacterium violaceum
Length = 296
Score = 155 bits (375), Expect = 2e-36
Identities = 81/178 (45%), Positives = 103/178 (57%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
+N+AF+GLGNMGG MA NL+ KGF V +D S DAL A G A+S
Sbjct: 2 ENIAFIGLGNMGGPMAVNLLNKGFKVSAFDLSADALAKVAAAGGRAASSAADAAESASVV 61
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 540
S+L + K V +YLG +G+ A KG+L+ID STID +++ A EKGL DAPV
Sbjct: 62 ISMLPAGKHVAGLYLGDNGLFARLPKGALVIDCSTIDAGTARKVAEGAREKGLSMLDAPV 121
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMG 714
SGG GA TL F+ GG ED + P+L MG FH G G+G AK+ NN L+G
Sbjct: 122 SGGTAGAAAGTLTFIVGGAAEDLAHARPVLEAMGKNIFHAGGAGAGQTAKICNNMLLG 179
>UniRef50_Q54CX6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Dictyostelium discoideum AX4
Length = 321
Score = 151 bits (365), Expect = 3e-35
Identities = 77/199 (38%), Positives = 112/199 (56%)
Frame = +1
Query: 157 RAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXX 336
R S+++ K V F+GLGNMGG A NL+KKG + +D SKD +N + G ANS
Sbjct: 15 RYMSTSSSKTVGFIGLGNMGGHQAINLIKKGHNLIVFDMSKDNMNRLKEKGAKIANSPAE 74
Query: 337 XXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG 516
++L ++ V +VY G++G+ + G+LL+DSSTIDP +++ IA +
Sbjct: 75 VAKEADVIVTMLPASAHVKNVYCGENGIFQTVRPGTLLLDSSTIDPATAREVASIAKKHQ 134
Query: 517 LGFTDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLT 696
D PVSGG GA TL FM GG ++DF + L MG HCG +G+G VAK+
Sbjct: 135 STMLDCPVSGGTGGAEAGTLTFMVGGSEQDFNTAKTYLECMGKNIVHCGDVGTGQVAKVC 194
Query: 697 NNXLMGXPRLAXADCXXHG 753
NN ++G +A ++ G
Sbjct: 195 NNLVLGISMIAVSEAMNLG 213
>UniRef50_UPI0000D56743 Cluster: PREDICTED: similar to
3-hydroxyisobutyrate dehydrogenase; n=1; Tribolium
castaneum|Rep: PREDICTED: similar to
3-hydroxyisobutyrate dehydrogenase - Tribolium castaneum
Length = 315
Score = 146 bits (353), Expect = 8e-34
Identities = 77/175 (44%), Positives = 101/175 (57%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+AF+G+GNMG MA NLVKKG TVR +D + NA + G N+ +
Sbjct: 26 LAFIGIGNMGSRMANNLVKKGETVRVFDLTP--ANAKSVPGAQVCNNQEEAVKDASVIIT 83
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+L + +V D LG +G++ HA KGSLLID STI P V +++ G F DAPVSG
Sbjct: 84 MLPNGDIVKDTVLGTNGILKHASKGSLLIDCSTIQPQVAQEVSKATYSAGFKFLDAPVSG 143
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLM 711
GV GA TL FM GG K+ + P+L MGA HCG G+G +AKL NN ++
Sbjct: 144 GVTGAEAGTLTFMVGGDKQVLNSADPILMKMGANVLHCGDSGAGQIAKLCNNLIL 198
>UniRef50_A7JGH8 Cluster: Predicted protein; n=1; Francisella
tularensis subsp. novicida GA99-3549|Rep: Predicted
protein - Francisella tularensis subsp. novicida
GA99-3549
Length = 293
Score = 144 bits (348), Expect = 3e-33
Identities = 80/186 (43%), Positives = 101/186 (54%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
KN+AF+GLG MG MA NL+ G+ V G+D S D LN NG A SI
Sbjct: 2 KNIAFIGLGCMGLHMAKNLIDNGYKVYGFDMSLDQLNKHQNNGGIAAKSIKEACGYADAI 61
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 540
L V +V DG++ AK G+++ID+STID N + A + L DAPV
Sbjct: 62 ILSLPGPNQVSNVCDSSDGILKIAKAGTIIIDTSTIDANTSVLLAKKAKQNNLHMLDAPV 121
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXP 720
SGG++GA NATL FM GG KE FER L MG K H G G G + KL NN L+G
Sbjct: 122 SGGIIGAQNATLTFMVGGDKEIFERCKNLFNSMGKKYLHVGDNGKGLIIKLINNMLLGIN 181
Query: 721 RLAXAD 738
+A ++
Sbjct: 182 MIAASE 187
>UniRef50_P28811 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=72;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Pseudomonas aeruginosa
Length = 298
Score = 142 bits (344), Expect = 1e-32
Identities = 78/177 (44%), Positives = 101/177 (57%)
Frame = +1
Query: 184 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 363
++AFLGLGNMGG MAANL+K G V +D A+ + G A+S
Sbjct: 3 DIAFLGLGNMGGPMAANLLKAGHRVNVFDLQPKAVLGLVEQGAQGADSALQCCEGAEVVI 62
Query: 364 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 543
S+L + + V +YLG DG++A LLID STI P +++ A KGL DAPVS
Sbjct: 63 SMLPAGQHVESLYLGDDGLLARVAGKPLLIDCSTIAPETARKVAEAAAAKGLTLLDAPVS 122
Query: 544 GGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMG 714
GGV GA TL+F+ GG E F R+ P+L MG FH G G+G VAK+ NN L+G
Sbjct: 123 GGVGGARAGTLSFIVGGPAEGFARARPVLENMGRNIFHAGDHGAGQVAKICNNMLLG 179
>UniRef50_A1QPH6 Cluster: 3-hydroxyisobutyrate dehydrogenase mmsB;
n=5; Mycobacterium|Rep: 3-hydroxyisobutyrate
dehydrogenase mmsB - Mycobacterium tuberculosis (strain
F11)
Length = 315
Score = 136 bits (328), Expect = 9e-31
Identities = 76/184 (41%), Positives = 104/184 (56%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+AFLGLGNMG M+ANLV G VRG+DP+ A + AA +GV S +
Sbjct: 4 IAFLGLGNMGAPMSANLVGAGHVVRGFDPAPTAASGAAAHGVAVFRSAPEAVAEADVVIT 63
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+L + +VV Y V+A A+ +L IDSSTI +++ +A G+ DAPVSG
Sbjct: 64 MLPTGEVVRRCYTD---VLAAARPATLFIDSSTISVTDAREVHALAESHGMLQLDAPVSG 120
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPRL 726
GV GA ATLAFM GG + R+ P+L M K HCG G+G AK+ NN ++ ++
Sbjct: 121 GVKGAAAATLAFMVGGDESTLRRARPVLEPMAGKIIHCGAAGAGQAAKVCNNMVLAVQQI 180
Query: 727 AXAD 738
A A+
Sbjct: 181 AIAE 184
>UniRef50_P63936 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase; n=25; Bacteria|Rep: Probable
3-hydroxyisobutyrate dehydrogenase - Mycobacterium bovis
Length = 294
Score = 136 bits (328), Expect = 9e-31
Identities = 76/184 (41%), Positives = 104/184 (56%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+AFLGLGNMG M+ANLV G VRG+DP+ A + AA +GV S +
Sbjct: 4 IAFLGLGNMGAPMSANLVGAGHVVRGFDPAPTAASGAAAHGVAVFRSAPEAVAEADVVIT 63
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+L + +VV Y V+A A+ +L IDSSTI +++ +A G+ DAPVSG
Sbjct: 64 MLPTGEVVRRCYTD---VLAAARPATLFIDSSTISVTDAREVHALAESHGMLQLDAPVSG 120
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPRL 726
GV GA ATLAFM GG + R+ P+L M K HCG G+G AK+ NN ++ ++
Sbjct: 121 GVKGAAAATLAFMVGGDESTLRRARPVLEPMAGKIIHCGAAGAGQAAKVCNNMVLAVQQI 180
Query: 727 AXAD 738
A A+
Sbjct: 181 AIAE 184
>UniRef50_A0UF54 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia multivorans ATCC
17616|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
- Burkholderia multivorans ATCC 17616
Length = 289
Score = 134 bits (325), Expect = 2e-30
Identities = 70/186 (37%), Positives = 101/186 (54%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
K V +GLGNMG +A++L + GF V G+D + +++ A GV P S+
Sbjct: 2 KTVGVIGLGNMGRGIASSLKRAGFDVLGFDANAESVRQLADEGVRPCASVAEIASAVDVL 61
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 540
L ++ +V V LG GV +HAK+G ++ID++T DPN +++ G+GF D PV
Sbjct: 62 ILSLPTSAIVEAVVLGDGGVASHAKRGLIVIDTTTADPNSTRKVAAALDAHGIGFIDGPV 121
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXP 720
SGG GA AT+ + GG E P+L + AKQ H G G+G V KL NN L G
Sbjct: 122 SGGPKGAATATMTMVLGGADEHIAAVQPVLSAISAKQVHVGPAGAGHVTKLLNNLLTGVH 181
Query: 721 RLAXAD 738
L ++
Sbjct: 182 LLVTSE 187
>UniRef50_Q399N0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=72;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 299
Score = 133 bits (322), Expect = 5e-30
Identities = 77/189 (40%), Positives = 98/189 (51%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ F+GLG+MG MA NL+K G V +D S DAL A G A S +
Sbjct: 3 IGFIGLGHMGAPMALNLLKAGHEVHAFDLSADALRALQDAGAQVAASPRDAASGATFVIT 62
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+L + V V G++GV+A G+ +IDSSTIDP + + E G F DAPVSG
Sbjct: 63 MLPAAPHVRSVLSGENGVLAGLGAGATVIDSSTIDPASAQAFGALVREHGGAFVDAPVSG 122
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPRL 726
G GA TL FM GG DFER P+L MG HCG G G VAK+ NN ++G
Sbjct: 123 GTGGAAAGTLTFMVGGSDADFERVKPVLAGMGKNIVHCGATGMGQVAKVCNNLVLGISMA 182
Query: 727 AXADCXXHG 753
A ++ G
Sbjct: 183 AVSEAMSLG 191
>UniRef50_P31937 Cluster: 3-hydroxyisobutyrate dehydrogenase,
mitochondrial precursor; n=38; Eumetazoa|Rep:
3-hydroxyisobutyrate dehydrogenase, mitochondrial
precursor - Homo sapiens (Human)
Length = 336
Score = 132 bits (320), Expect = 8e-30
Identities = 75/199 (37%), Positives = 107/199 (53%)
Frame = +1
Query: 157 RAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXX 336
R+ +S T V F+GLGNMG MA NL+K G+ + YD DA G +S
Sbjct: 34 RSVASKTP--VGFIGLGNMGNPMAKNLMKHGYPLIIYDVFPDACKEFQDAGEQVVSSPAD 91
Query: 337 XXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG 516
++L ++ ++ Y G +G++ KKGSLLIDSSTIDP V K++ + G
Sbjct: 92 VAEKADRIITMLPTSINAIEAYSGANGILKKVKKGSLLIDSSTIDPAVSKELAKEVEKMG 151
Query: 517 LGFTDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLT 696
F DAPVSGGV A + L FM GG +++F + LL MG+ +CG +G+G AK+
Sbjct: 152 AVFMDAPVSGGVGAARSGNLTFMVGGVEDEFAAAQELLGCMGSNVVYCGAVGTGQAAKIC 211
Query: 697 NNXLMGXPRLAXADCXXHG 753
NN L+ + A+ G
Sbjct: 212 NNMLLAISMIGTAEAMNLG 230
>UniRef50_A0QSJ0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 290
Score = 130 bits (315), Expect = 3e-29
Identities = 75/184 (40%), Positives = 99/184 (53%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+AFLGLG+MGG MAANL G TVRG+DP + AA G+ + +
Sbjct: 4 IAFLGLGHMGGPMAANLAAAGHTVRGFDPMPASREAAEAKGIKVFGTGAEAASEAEVVIT 63
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
L + +V Y V+ A G+L ID+STI + + + ALEKG DAPVSG
Sbjct: 64 SLPNGDIVKSCYAE---VLPAAPTGTLFIDTSTISVDDARTVHTQALEKGHAQLDAPVSG 120
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPRL 726
GV GA TLAFM GG + ER+ P+L M K HCG G+G AKL NN ++ ++
Sbjct: 121 GVKGATAGTLAFMVGGEDDAVERARPILDPMAGKIIHCGGSGTGQAAKLCNNMVLAVQQI 180
Query: 727 AXAD 738
A +
Sbjct: 181 AIGE 184
>UniRef50_Q0K0E2 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1;
Ralstonia eutropha H16|Rep: 3-Hydroxyisobutyrate
dehydrogenase - Ralstonia eutropha (strain ATCC 17699 /
H16 / DSM 428 / Stanier 337)(Cupriavidus necator (strain
ATCC 17699 / H16 / DSM 428 / Stanier337))
Length = 299
Score = 128 bits (308), Expect = 2e-28
Identities = 71/174 (40%), Positives = 98/174 (56%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+AF+GLGNMG MA NLV+ G V+G+D S+ AL A G S+ S
Sbjct: 4 IAFIGLGNMGMPMALNLVRAGHDVQGFDISEAALAGFAGQGGQSQRSVAAAVDGASIVIS 63
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
I+ + V ++Y GV+ A G+LLI+SSTI P + + A + G DAPV+G
Sbjct: 64 IVRNADDVKNLYCTAGGVLDVAAPGALLIESSTIGPAAARAVAAEAAQAGFAMLDAPVAG 123
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXL 708
G GA A L FM GG + F+R+ P+L MGA+ F+ G G+G +AKL NN +
Sbjct: 124 GQAGAREARLTFMVGGARTAFDRAEPVLRQMGARIFYAGASGNGQIAKLCNNLI 177
>UniRef50_A0JUJ6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Micrococcineae|Rep: 3-hydroxyisobutyrate dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 300
Score = 128 bits (308), Expect = 2e-28
Identities = 71/175 (40%), Positives = 96/175 (54%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
VA++GLGNMGG M+ANL K G VRG+D + +A+ AA GV P SI +
Sbjct: 4 VAWIGLGNMGGSMSANLAKAGHDVRGFDLNPEAVAAAEAGGVKPVASIAAAVDGADVVFT 63
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+L + VYLG+DGV+AHA + +LL+DSSTID + + A G F DAPVSG
Sbjct: 64 MLPKGEHARAVYLGEDGVLAHADRRTLLVDSSTIDIASAQALHDAAAAAGFRFVDAPVSG 123
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLM 711
G+ GA TL FM GG + + M + G +G AK+ NN ++
Sbjct: 124 GMSGAKAGTLTFMIGGDAGAVAEATEYIRPMASNIIPTGGPTTGQAAKICNNLML 178
>UniRef50_Q9K9L1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Bacillus|Rep: 3-hydroxyisobutyrate dehydrogenase -
Bacillus halodurans
Length = 299
Score = 126 bits (305), Expect = 5e-28
Identities = 71/187 (37%), Positives = 94/187 (50%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
+ V F+GLG MG M +LV KGF S+ + A + G S
Sbjct: 3 QKVGFVGLGTMGLPMTKHLVDKGFETYVKSRSRGPIEEAIQYGAIEVESYKELMETADIV 62
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 540
+ L + V+DVY G+DG++A +G +LID ST+D ++ EKG F DAPV
Sbjct: 63 MTCLPLPETVIDVYEGEDGLIAGLSQGKILIDHSTVDRETNVRVAEQIKEKGGAFLDAPV 122
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXP 720
SGG MGA TL M GG + FERS +L G H G IGSG V KL NN ++G
Sbjct: 123 SGGPMGAKAGTLTIMCGGEADSFERSKEVLGAYGDYIVHVGPIGSGTVVKLANNMVIGVH 182
Query: 721 RLAXADC 741
+ +C
Sbjct: 183 QAVLGEC 189
>UniRef50_Q0SBQ9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=12;
Actinomycetales|Rep: 2-hydroxy-3-oxopropionate reductase
- Rhodococcus sp. (strain RHA1)
Length = 294
Score = 126 bits (303), Expect = 9e-28
Identities = 71/175 (40%), Positives = 92/175 (52%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+AF+GLG MG MA NL K G V GY+ D A + G T A+SI
Sbjct: 4 IAFIGLGIMGSPMACNLAKAGHQVVGYNLIPDRTAALVEAGGTAADSIAKAVAGADVVAV 63
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
++ + V V G+DGV H G+L+ID S+I P+V + A E+G DAPVSG
Sbjct: 64 MVPDSPDVQAVLTGEDGVFEHTPSGALIIDFSSIRPDVTTALAAQATERGFRLIDAPVSG 123
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLM 711
G GA NA L+ M GG EDFE + P+L V+G H G GSG K N ++
Sbjct: 124 GEAGAVNAALSIMVGGAPEDFESARPILDVVGKTVVHVGPNGSGQTVKAANQLIV 178
>UniRef50_Q55702 Cluster: Uncharacterized oxidoreductase slr0229;
n=4; Cyanobacteria|Rep: Uncharacterized oxidoreductase
slr0229 - Synechocystis sp. (strain PCC 6803)
Length = 290
Score = 126 bits (303), Expect = 9e-28
Identities = 73/186 (39%), Positives = 97/186 (52%), Gaps = 2/186 (1%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPS--KDALNAAAKNGVTPANSIXXXXXXXXXX 360
+A GLG MG MA NLVK G+ GY+ + + ++ AAK GV SI
Sbjct: 6 IAVFGLGVMGSPMAQNLVKNGYQTVGYNRTLERPSVQEAAKAGVKVVTSIAVAAANADII 65
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 540
+ + K V + LG G+ +AK +L+ID STI ++ +GL F DAPV
Sbjct: 66 LTCVGDEKDVQQLILGSGGIAEYAKPQALIIDCSTIGKTAAYELATNLKLQGLRFLDAPV 125
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXP 720
+GG +GA N TL M GG DFE +LP+L +G K HCG GSG KL N L G
Sbjct: 126 TGGDVGAINGTLTIMVGGDISDFEEALPVLKSIGEKIVHCGPSGSGQAVKLCNQVLCGIH 185
Query: 721 RLAXAD 738
+A A+
Sbjct: 186 AIAAAE 191
>UniRef50_Q83D20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Coxiella burnetii
Length = 297
Score = 125 bits (301), Expect = 2e-27
Identities = 67/184 (36%), Positives = 101/184 (54%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ F+GLG+MG M NL+K V+ YD +A+ A K G T A S +
Sbjct: 4 IGFIGLGHMGQPMVNNLIKNNCLVKVYDVIDEAVEKAVKTGATAAASPAEVAEEADVVFT 63
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+L ++ V + L G+ A + ++ IDSS+ID +++ A ++G+ DAPVSG
Sbjct: 64 MLQTSDQVRNCCLSAKGIFATINRQAIYIDSSSIDIEGSRELHKEAKKRGISMLDAPVSG 123
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPRL 726
GV A A L FM GG KEDFER+ +L ++G K + G G+G AK+ NN L+G +
Sbjct: 124 GVAAAEAAGLTFMVGGEKEDFERAKRVLGILGKKIIYAGSDGAGAAAKICNNMLLGISMI 183
Query: 727 AXAD 738
A ++
Sbjct: 184 AVSE 187
>UniRef50_Q9V8M5 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor; n=4;
Diptera|Rep: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor - Drosophila
melanogaster (Fruit fly)
Length = 324
Score = 124 bits (300), Expect = 2e-27
Identities = 74/200 (37%), Positives = 101/200 (50%), Gaps = 2/200 (1%)
Frame = +1
Query: 145 TAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPAN 324
T R + KN+ F+GLGNMG MA+NL+K G + +D SK A + A G T
Sbjct: 17 TLVRAMSTQGGAKNIGFVGLGNMGANMASNLIKAGHKLHVFDISKPACDGLAAKGATVYA 76
Query: 325 SIXXXXXXXXXXXSILTSNKVVLDVY--LGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFP 498
++L +N +V Y + DGV K ++ IDSSTI P++ K +
Sbjct: 77 KTSELAKNSDFVITMLPNNAIVDASYDEMTADGV----NKDTIFIDSSTISPDLVKSLQK 132
Query: 499 IALEKGLGFTDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSG 678
KG F DAPVSGGV GA ATL FM GG + ++ +L MG K HCG G G
Sbjct: 133 KISAKGARFIDAPVSGGVPGAEQATLTFMVGGTEAEYNAVKAVLECMGKKITHCGVYGMG 192
Query: 679 XVAKLTNNXLMGXPRLAXAD 738
AKL NN ++ + ++
Sbjct: 193 QAAKLCNNMMLAISMIGVSE 212
>UniRef50_Q8ES28 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=13;
Bacillaceae|Rep: 3-hydroxyisobutyrate dehydrogenase -
Oceanobacillus iheyensis
Length = 299
Score = 124 bits (299), Expect = 3e-27
Identities = 68/177 (38%), Positives = 98/177 (55%), Gaps = 1/177 (0%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ F+GLGNMG M+ L+ G+ V G+D +++ K+G A S +
Sbjct: 4 IGFIGLGNMGLPMSIGLMNSGYEVIGFDVNEERSLLFKKSGGNIALSSADLVAESDVILT 63
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
L SNK V VYL K G++ H ++ID+ST+ P + +Q+ E+ + F APVSG
Sbjct: 64 SLPSNKAVEAVYLNKGGLLDHCNSSQVVIDTSTVAPELNQQLEASLSERSIPFLAAPVSG 123
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCG-QIGSGXVAKLTNNXLMG 714
GV+GA N TL M GG++E F++ +L V+G FH G QI G KL NN L+G
Sbjct: 124 GVVGAENQTLTVMVGGKEETFQKVKDILNVIGGNVFHVGEQIDKGTTVKLINNLLIG 180
>UniRef50_A3I4V2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Bacillus sp. B14905|Rep: 3-hydroxyisobutyrate
dehydrogenase - Bacillus sp. B14905
Length = 316
Score = 124 bits (299), Expect = 3e-27
Identities = 67/188 (35%), Positives = 106/188 (56%), Gaps = 1/188 (0%)
Frame = +1
Query: 178 DKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXX 357
++ + F+GLGNMG M+ NL+K + V G+D + A+ + G S
Sbjct: 21 NRKLGFIGLGNMGLPMSINLLKANYEVYGFDTNAKAVELFTEAGGIGLASAKDVAKQCDV 80
Query: 358 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 537
+ L + ++V VYL ++G++ HAKKG+LL+D ST++P++ + A GL + AP
Sbjct: 81 VMTSLPTPQIVEMVYLSEEGIIHHAKKGALLVDFSTVNPDLNDSLHKEASTLGLRYLGAP 140
Query: 538 VSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGS-GXVAKLTNNXLMG 714
VSGGV+GA NATL M GG K+D++ + + ++G +H G S G KL NN ++G
Sbjct: 141 VSGGVIGAVNATLTIMVGGGKDDYDSASEIFGIVGKNIYHLGLSSSVGTRLKLLNNLMIG 200
Query: 715 XPRLAXAD 738
A A+
Sbjct: 201 FYTEAVAE 208
>UniRef50_Q4FMJ3 Cluster: 6-phosphogluconate dehydrogenase; n=2;
Candidatus Pelagibacter ubique|Rep: 6-phosphogluconate
dehydrogenase - Pelagibacter ubique
Length = 289
Score = 123 bits (297), Expect = 5e-27
Identities = 64/178 (35%), Positives = 105/178 (58%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
+N++F+G+G MG MA NL+K GF +R Y+ S+D + + G + SI
Sbjct: 2 QNISFIGIGLMGFPMAKNLLKSGFNLRAYNRSQDKADRLKEFGAEISTSIKDVVTNSDVI 61
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 540
++LT + V V +G D +++ K+G+ +ID S+++P + K+ F I EK + + DAPV
Sbjct: 62 ITMLTDDAAVEKV-MGSDEFISNIKEGATVIDMSSVNPVITKKYFKILKEKNINYLDAPV 120
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMG 714
SGG +GA A+LA M GG +E F++ LL ++G G + SG ++KL N ++G
Sbjct: 121 SGGTIGAEEASLAIMVGGDEETFKQCYDLLKILGNPTL-VGPVTSGQISKLANQIIVG 177
>UniRef50_A5V0D4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Chloroflexaceae|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Roseiflexus sp. RS-1
Length = 303
Score = 122 bits (295), Expect = 9e-27
Identities = 69/186 (37%), Positives = 98/186 (52%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
+ V F+GLG MG MA N++K GF +R ++ + ++ A G PA+S
Sbjct: 5 ERVGFIGLGIMGRGMARNILKAGFPLRVWNRTASRMDELAAEGAGPASSPGDLAFHSDII 64
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 540
+ ++ V V LG+ GV+ A+ GSL+ID STI P ++I E+ + DAPV
Sbjct: 65 ITCVSDTPDVEQVLLGEGGVIHGARPGSLVIDMSTISPRATQRIAAHLAERHIHMLDAPV 124
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXP 720
SGG GA TL+ M GG FER+LP+ MG H G IG+G KL N L+
Sbjct: 125 SGGSEGAARGTLSIMVGGDVTQFERALPVFQAMGTTITHLGPIGAGQTTKLVNQILVVGH 184
Query: 721 RLAXAD 738
LA ++
Sbjct: 185 ALAMSE 190
>UniRef50_A6NVP0 Cluster: Putative uncharacterized protein; n=1;
Bacteroides capillosus ATCC 29799|Rep: Putative
uncharacterized protein - Bacteroides capillosus ATCC
29799
Length = 306
Score = 122 bits (294), Expect = 1e-26
Identities = 66/189 (34%), Positives = 94/189 (49%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ F+GLG MG MA NL+ G+ V +D + A+ G S
Sbjct: 8 IGFIGLGAMGRPMATNLLTAGYEVHAFDVVEAAVKEMEGKGAIGHPSAGEMAGHVDVIIC 67
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
L + K+V GK+GV + K+G+++ID S++ PN K + A EKG+ + DAPVSG
Sbjct: 68 SLPNAKIVEGTMCGKNGVFENCKEGTVIIDMSSVAPNTTKAMAKKAAEKGIHYIDAPVSG 127
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPRL 726
GV GA TL M G E F + P+ V+G +H G+ G G K+ NN L+G
Sbjct: 128 GVSGAAAGTLTIMVGADDETFNKVKPIFDVLGKNIYHVGEAGGGDAIKMVNNLLLGCNMA 187
Query: 727 AXADCXXHG 753
A A+ G
Sbjct: 188 ALAEALTLG 196
>UniRef50_Q1AVA4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=6;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 309
Score = 121 bits (291), Expect = 3e-26
Identities = 70/190 (36%), Positives = 101/190 (53%), Gaps = 1/190 (0%)
Frame = +1
Query: 148 AARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPS-KDALNAAAKNGVTPAN 324
A R + + V F+GLG MG MA NL++ G+++ ++ + + A A + G A
Sbjct: 4 APRERRKAGMAEKVGFIGLGIMGRPMAENLIRAGYSLTVHNRTHQKAEEFAQQTGARTAK 63
Query: 325 SIXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIA 504
S ++L + V V G+ GV+ ++GSLLID STI P V +Q+ A
Sbjct: 64 SPKEVAGQSDIIITMLPDSPDVESVVAGEGGVLEGMREGSLLIDMSTISPAVARQLAAKA 123
Query: 505 LEKGLGFTDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXV 684
E+G DAPVSGG +GA TL+ M GG +EDF R+ PL VMG H G G+G +
Sbjct: 124 RERGASMLDAPVSGGDVGAREGTLSIMVGGSEEDFGRARPLFEVMGKTVTHVGPSGAGQI 183
Query: 685 AKLTNNXLMG 714
K N ++G
Sbjct: 184 VKAANQIVVG 193
>UniRef50_Q1V2R0 Cluster: MmsB-like protein; n=2; Candidatus
Pelagibacter ubique|Rep: MmsB-like protein - Candidatus
Pelagibacter ubique HTCC1002
Length = 308
Score = 120 bits (289), Expect = 5e-26
Identities = 66/185 (35%), Positives = 98/185 (52%)
Frame = +1
Query: 184 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 363
++AF+G+GNMG MA LVK G V+ +D S + + A ++G+ ++I
Sbjct: 4 HIAFIGVGNMGNPMADQLVKAGKEVKAFDVSPEVIKIAKESGLNVVSTIDELLDGASTVI 63
Query: 364 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 543
S+L K V +YLG G++ K L+ID STID ++ + + G+ DAPV+
Sbjct: 64 SMLPEGKHVRSLYLGDKGILNKIPKECLIIDCSTIDIETSLELGNESKKLGIKMIDAPVT 123
Query: 544 GGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPR 723
GGVMGA L F+ GG E + PL +MG K H G GSG K+ NN +G
Sbjct: 124 GGVMGARIGKLNFLVGGSDEAVALAKPLFDIMGQKILHAGVQGSGVGVKICNNMSLGISM 183
Query: 724 LAXAD 738
+A ++
Sbjct: 184 IAASE 188
>UniRef50_Q8KL12 Cluster: Probable 6-phosphogluconate dehydrogenase
protein; n=1; Rhizobium etli CFN 42|Rep: Probable
6-phosphogluconate dehydrogenase protein - Rhizobium
etli (strain CFN 42 / ATCC 51251)
Length = 294
Score = 120 bits (288), Expect = 6e-26
Identities = 71/188 (37%), Positives = 98/188 (52%)
Frame = +1
Query: 166 SSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXX 345
S + VAF+GLG MGG MA +L+ F V G+D S +A A G PA ++
Sbjct: 2 SPRKNLRVAFIGLGAMGGPMAQHLLSAQFEVTGFDLSAEARERFAAVGGVPAETVAEAFN 61
Query: 346 XXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGF 525
++L + K+V D L KDG +L+ID S+ PN +++ +KGL
Sbjct: 62 GADVAVTMLPNGKIVQDA-LFKDGAWQSLSADALVIDMSSSAPNDTRELAERLHQKGLRL 120
Query: 526 TDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNX 705
DAPVSGGV A +L MAGG +D +++ P+L MG + F G IGSG K NN
Sbjct: 121 VDAPVSGGVKRAVEGSLTIMAGGASDDIDQADPILCAMGGQIFRTGPIGSGHAMKAINNF 180
Query: 706 LMGXPRLA 729
+ G LA
Sbjct: 181 VSGAGVLA 188
>UniRef50_Q4ZQL5 Cluster: 3-hydroxyisobutyrate dehydrogenase
precursor; n=11; Proteobacteria|Rep:
3-hydroxyisobutyrate dehydrogenase precursor -
Pseudomonas syringae pv. syringae (strain B728a)
Length = 296
Score = 119 bits (286), Expect = 1e-25
Identities = 64/181 (35%), Positives = 94/181 (51%)
Frame = +1
Query: 196 LGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSILT 375
+GLGNMGG MAA L KGF V G+D S+ AL A GV P L
Sbjct: 8 IGLGNMGGGMAATLAGKGFDVSGFDLSQAALAQAESKGVKPVADRTQLIQGVDILILSLP 67
Query: 376 SNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVM 555
+ V V LG G+ +KG +++D++T P + +++ + G+ F DAPVSGG
Sbjct: 68 KAEHVESVCLGAGGINEVGRKGLIVVDTTTSTPEMSRKVAAELAKNGIAFIDAPVSGGPK 127
Query: 556 GAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPRLAXA 735
GA +++ + G D R++P+L M + H GQ G+G VAK+ NN L ++ A
Sbjct: 128 GAATGSMSMVIGAEDADLARAMPVLEGMSGTRVHVGQCGAGNVAKIANNMLAACHLISTA 187
Query: 736 D 738
+
Sbjct: 188 E 188
>UniRef50_Q22B54 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Tetrahymena thermophila SB210
Length = 316
Score = 119 bits (286), Expect = 1e-25
Identities = 72/193 (37%), Positives = 102/193 (52%), Gaps = 2/193 (1%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKG-FTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXX 357
+ V F+GLGNMGG MA NL +KG F V +D +KD+L AK G+ +
Sbjct: 17 ETVGFIGLGNMGGPMALNLARKGGFEVIAFDVNKDSLKKYAKEGLAVCEDVTVLARKANK 76
Query: 358 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 537
++L ++ V V G++G+ + K SL IDSSTI + +I+ A + + DAP
Sbjct: 77 FVTMLPNSSHVSSVLEGENGLFQKSAKNSLFIDSSTISYHAAIKIYENAKKVNQRYIDAP 136
Query: 538 VSGGVMGAXNATLAFMAGG-RKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMG 714
VSGGV A TL FM G KE F+ LL MG +C + G+G +AK+ NN +G
Sbjct: 137 VSGGVGAATAGTLTFMVGAENKELFQECKNLLQHMGKNIANCEKPGAGSIAKICNNMALG 196
Query: 715 XPRLAXADCXXHG 753
+A A+ G
Sbjct: 197 IEMIAVAEAISLG 209
>UniRef50_Q11FC5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Rhizobiales|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mesorhizobium sp. (strain
BNC1)
Length = 292
Score = 118 bits (283), Expect = 2e-25
Identities = 67/176 (38%), Positives = 92/176 (52%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+AF+G G MG M ANL K GF ++ YD S AL +GVT A+S+ +
Sbjct: 4 LAFIGAGVMGRPMIANLRKAGFALKAYDRSPAALENLRSDGVTVADSLAAAVAGADVVVT 63
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+L V V LG+DG+ G+L+ID STI + + I +G+ DAPVSG
Sbjct: 64 MLPDTPHVQSVLLGEDGIGTLLPTGTLVIDMSTISASGIRAIGQDLASRGVDLVDAPVSG 123
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMG 714
GV GA L+ M GG E F ++ P+L MG H G +G G V K+ N ++G
Sbjct: 124 GVRGAIAGELSIMCGGSPEAFAKARPVLEGMGTTIIHAGDLGMGQVFKMCNQLMVG 179
>UniRef50_Q9A8J9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=24;
Alphaproteobacteria|Rep: 3-hydroxyisobutyrate
dehydrogenase - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 298
Score = 117 bits (282), Expect = 3e-25
Identities = 71/184 (38%), Positives = 92/184 (50%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+AF+GLGNMGG MAAN K VR +D S A+ A G A S+ +
Sbjct: 4 IAFIGLGNMGGGMAANQAKAQHQVRAFDLSAAAVERAVAAGCLAAASVAEAVAEAEIVIT 63
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+L + V VY + ++ +A K +LLID STID + + + A E G F DAPVSG
Sbjct: 64 MLPAGPHVRAVYA--EQILPNAPKSALLIDCSTIDVDSARVVARQAAEAGFRFADAPVSG 121
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPRL 726
G+M A TLAFM G DF L M H G G+G AK+ NN L+G L
Sbjct: 122 GIMAAEAGTLAFMVGCEASDFAAVEAALAPMSRVTIHAGDHGAGQAAKICNNMLLGVSML 181
Query: 727 AXAD 738
+
Sbjct: 182 GTCE 185
>UniRef50_Q1QWU9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Chromohalobacter salexigens DSM 3043|Rep:
3-hydroxyisobutyrate dehydrogenase - Chromohalobacter
salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB13768)
Length = 310
Score = 117 bits (282), Expect = 3e-25
Identities = 70/187 (37%), Positives = 95/187 (50%)
Frame = +1
Query: 178 DKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXX 357
D N+ +GLG MGG MA L GFTV G D + A + A G++ +
Sbjct: 10 DMNIVVIGLGQMGGNMAMTLHAAGFTVTGTDVADAARDNLAARGLS-VTRLDALPEADVY 68
Query: 358 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 537
S+ TS V +V G++ A KGS+++D+ST DP V +++ +E GL + DAP
Sbjct: 69 LLSLPTSAHV-REVIETSPGLLQRAPKGSVIVDTSTSDPAVTRELAGKVVEAGLEWLDAP 127
Query: 538 VSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGX 717
VSGG GA + L + GG ER P+L M A+ H G GSG V KL NN L
Sbjct: 128 VSGGPAGAASGALGMLLGGESATIERLAPMLEAMSARHTHVGPAGSGHVVKLANNYLCAA 187
Query: 718 PRLAXAD 738
L A+
Sbjct: 188 HLLTTAE 194
>UniRef50_Q0QLF5 Cluster: 2-hydroxymethyl glutarate dehydrogenase;
n=1; Eubacterium barkeri|Rep: 2-hydroxymethyl glutarate
dehydrogenase - Eubacterium barkeri (Clostridium
barkeri)
Length = 301
Score = 116 bits (280), Expect = 6e-25
Identities = 62/189 (32%), Positives = 97/189 (51%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ F+GLG MG MA NL+K+G TV +D + + A G + +
Sbjct: 7 IGFIGLGAMGKPMAINLLKEGVTVYAFDLMEANVAAVVAQGAQACENNQKVAAASDIIFT 66
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
L + +V V G GV++ K G++++D S++ P+ ++ +A EKG+ + DAPVSG
Sbjct: 67 SLPNAGIVETVMNGPGGVLSACKAGTVIVDMSSVSPSSTLKMAKVAAEKGIDYVDAPVSG 126
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPRL 726
G GA TL M G + FE+ P+L V+G +H G G+G K+ NN L+G
Sbjct: 127 GTKGAEAGTLTIMVGASEAVFEKIQPVLSVIGKDIYHVGDTGAGDAVKIVNNLLLGCNMA 186
Query: 727 AXADCXXHG 753
+ A+ G
Sbjct: 187 SLAEALVLG 195
>UniRef50_A4IN46 Cluster: 3-hydroxyisobutyrate dehydrogenase-like
protein; n=2; Geobacillus|Rep: 3-hydroxyisobutyrate
dehydrogenase-like protein - Geobacillus
thermodenitrificans (strain NG80-2)
Length = 304
Score = 116 bits (280), Expect = 6e-25
Identities = 64/190 (33%), Positives = 100/190 (52%)
Frame = +1
Query: 184 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 363
NV F+GLG MG MA L+ GF V Y+ + + ++G A +I
Sbjct: 3 NVGFIGLGMMGSRMAKRLLDAGFPVTVYNRTPEKAAILVESGARQAETIAALASEVDVIC 62
Query: 364 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 543
+ L+ V++VY G+ GV++ A++G + +D +T+ P + + A E+G+ + DAPVS
Sbjct: 63 TCLSMPDDVINVYTGEGGVLSAARRGVICLDFTTVGPKTSRFVAGRAGERGVAYLDAPVS 122
Query: 544 GGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPR 723
GG GA TL M GG + +ER PLL V+G + G+ G+G AK+ N L+
Sbjct: 123 GGPEGAEQGTLTIMVGGDQAAWERVRPLLSVLGKTVEYLGESGAGSAAKILNQYLVAVHS 182
Query: 724 LAXADCXXHG 753
+A A+ G
Sbjct: 183 VAAAEAMVAG 192
>UniRef50_O34948 Cluster: Uncharacterized oxidoreductase ykwC; n=19;
cellular organisms|Rep: Uncharacterized oxidoreductase
ykwC - Bacillus subtilis
Length = 288
Score = 116 bits (280), Expect = 6e-25
Identities = 63/186 (33%), Positives = 99/186 (53%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
K + F+GLG MG MA++++ G V Y +K+ + + G +++
Sbjct: 3 KTIGFIGLGVMGKSMASHILNDGHPVLVYTRTKEKAESILQKGAIWKDTVKDLSKEADVI 62
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 540
+++ V +VY G +G++ +AK+G+ LID +T P++ K+I A EK L DAPV
Sbjct: 63 ITMVGYPSDVEEVYFGSNGIIENAKEGAYLIDMTTSKPSLAKKIAEAAKEKALFALDAPV 122
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXP 720
SGG +GA N TLA M GG KE FE +P+ +MG + G GSG K+ N +
Sbjct: 123 SGGDIGAQNGTLAIMVGGEKEAFEACMPIFSLMGENIQYQGPAGSGQHTKMCNQIAIAAG 182
Query: 721 RLAXAD 738
+ A+
Sbjct: 183 MIGVAE 188
>UniRef50_Q41DK0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Bacillaceae|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Exiguobacterium sibiricum
255-15
Length = 293
Score = 115 bits (277), Expect = 1e-24
Identities = 64/186 (34%), Positives = 98/186 (52%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
K + F+GLG MG M NL+K GF+V+GY+ +K+ ++G ++I
Sbjct: 3 KTIGFIGLGVMGQGMVRNLLKAGFSVKGYNRTKEKGLPLEQDGAVIVDTIQEAVTDVDVV 62
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 540
SI+ + V ++YL +DG++A A G+++ID +T P + +I A + GL DAPV
Sbjct: 63 ISIVGYPQDVEEIYLAEDGILASANPGTIVIDMTTSSPALAIRIAEQAAQTGLHALDAPV 122
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXP 720
+GG +GA N TLA + GG + F+ PL MG G G G AKL N +
Sbjct: 123 TGGDLGAKNGTLAILVGGEEAAFDTVKPLFEAMGKSIARFGGPGQGQSAKLANQIAIAGS 182
Query: 721 RLAXAD 738
+ A+
Sbjct: 183 MIGTAE 188
>UniRef50_A3RRS1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=11;
Betaproteobacteria|Rep: 2-hydroxy-3-oxopropionate
reductase - Ralstonia solanacearum UW551
Length = 298
Score = 114 bits (275), Expect = 2e-24
Identities = 71/175 (40%), Positives = 90/175 (51%), Gaps = 4/175 (2%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+AF+GLGNMG M +LV G VR Y +A + A G P +S +
Sbjct: 4 IAFIGLGNMGSPMVGHLVAAGHAVRAYVRRPEAADRARALGAEPCDSPADAARDAEVVFT 63
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKG----SLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 534
+TS V V LG DGV+ A +G ++ ID STI ++I GL F DA
Sbjct: 64 NVTSTADVEAVLLGPDGVIHGAPRGKPGSAVCIDHSTISAVATRRIAAELETAGLDFLDA 123
Query: 535 PVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTN 699
PVSGG MGA ATL+ M GG+ E ER PLL ++G H G G+G VAK N
Sbjct: 124 PVSGGTMGAQKATLSIMVGGKAEVLERVRPLLQLLGTTITHIGDHGAGQVAKACN 178
>UniRef50_Q930C6 Cluster: Probable; n=8; Alphaproteobacteria|Rep:
Probable - Rhizobium meliloti (Sinorhizobium meliloti)
Length = 295
Score = 113 bits (273), Expect = 4e-24
Identities = 66/184 (35%), Positives = 91/184 (49%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
VA +G G MGG + A LV+ G + +DP D + A G A S
Sbjct: 5 VALIGAGAMGGSIGARLVETGNRLTVFDPGPDKVQALVDKGAFAAPSAAEAAAVSDYVIL 64
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
L + +V G GV A A+ G+L+ID S+IDPN KQ+ A EKGL + D+P+SG
Sbjct: 65 SLNAPAIVRQAVFGDAGVAAGAQAGTLIIDMSSIDPNATKQLAADAAEKGLRWVDSPLSG 124
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPRL 726
G A L MAGG +D + + +L + + H G +G+G KL N L G L
Sbjct: 125 GAPKALIGELTLMAGGTAQDVKDAHAVLRHVASNYTHMGSVGAGQTTKLINQVLCGLGFL 184
Query: 727 AXAD 738
A A+
Sbjct: 185 AVAE 188
>UniRef50_A6P2M7 Cluster: Putative uncharacterized protein; n=2;
Bacteria|Rep: Putative uncharacterized protein -
Bacteroides capillosus ATCC 29799
Length = 321
Score = 113 bits (272), Expect = 5e-24
Identities = 61/171 (35%), Positives = 92/171 (53%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+AF+G+G MG M NL+K G+++ Y +K G A+++ S
Sbjct: 38 IAFIGVGIMGKSMVRNLMKAGYSLTIYSRTKAKCEDVIAEGAVWADTVADCVRDAEAVFS 97
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
I+ K V +VY G G++++A+ G+L++D +T P + ++I+ KGL DAPV+G
Sbjct: 98 IVGYPKDVEEVYFGDGGIISNAQPGALIVDMTTSSPALAERIWEAGKAKGLRPLDAPVTG 157
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTN 699
G GA TL+ + GG K DF+ LPL MG H G G+G AKL N
Sbjct: 158 GDTGAKAGTLSILVGGDKVDFDACLPLFQAMGKIIVHMGSAGAGQHAKLAN 208
>UniRef50_A2SP40 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Methylibium petroleiphilum PM1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Methylibium petroleiphilum (strain PM1)
Length = 297
Score = 113 bits (272), Expect = 5e-24
Identities = 69/185 (37%), Positives = 95/185 (51%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
K + +GLGN+GG M L+ +G V G+D S A AAA++G S
Sbjct: 2 KEIGLIGLGNIGGGMCRRLLDRGIGVVGFDLSPAATKAAAEHGARIEVSPAAVAQQVDVV 61
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 540
+ L + +V DVYLGK G+VA A+ GS LI++STIDPN +++ A + G+ D +
Sbjct: 62 VTSLPNPPIVRDVYLGKQGLVAQARPGSTLIETSTIDPNTIREVAQAATKSGIRILDIAL 121
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXP 720
SG A L F GG E ++ L LL V+ K G IG+ KL NN LM
Sbjct: 122 SGEPPQAVLGELVFQVGGPDELIDQHLELLQVLAKKINRTGGIGTAKTVKLVNN-LMSLG 180
Query: 721 RLAXA 735
+A A
Sbjct: 181 NVAVA 185
>UniRef50_Q9SUC0 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor; n=13;
Magnoliophyta|Rep: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor - Arabidopsis
thaliana (Mouse-ear cress)
Length = 347
Score = 113 bits (272), Expect = 5e-24
Identities = 70/217 (32%), Positives = 108/217 (49%), Gaps = 12/217 (5%)
Frame = +1
Query: 139 LYTAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTP 318
L+ + + +SN +NV F+GLGNMG M NL++ G+ V +D ++D + + GV+
Sbjct: 24 LHRFSSSSQNSNQFQNVGFIGLGNMGFRMVNNLIRAGYKVTVHDINRDVMKMFTEMGVSS 83
Query: 319 ANSIXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAK--KGSLLIDSSTIDPNVPKQI 492
+ ++L S+ V+DVY G +G++ + +L IDSSTIDP ++I
Sbjct: 84 RETPYEVAQDSEVVITMLPSSSHVMDVYTGTNGLLLGENDIRPALFIDSSTIDPQTTRKI 143
Query: 493 FPIALEKGLG----------FTDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMG 642
L DAPVSGGV+ A TL FM GG ++ + + P+L MG
Sbjct: 144 SLAVSNCNLKEKRDNWEKPVMLDAPVSGGVLAAEAGTLTFMVGGPEDAYLAARPILQSMG 203
Query: 643 AKQFHCGQIGSGXVAKLTNNXLMGXPRLAXADCXXHG 753
+CG G+G AK+ NN M L ++ G
Sbjct: 204 RTSIYCGGSGNGSAAKICNNLAMAVSMLGTSEALALG 240
>UniRef50_A1SIN3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Nocardioides sp. JS614|Rep: 3-hydroxyisobutyrate
dehydrogenase - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 308
Score = 113 bits (271), Expect = 7e-24
Identities = 65/189 (34%), Positives = 94/189 (49%), Gaps = 3/189 (1%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
+ +AF+GLGNMG MA NL+ GF V G+D +A+ G+ A +
Sbjct: 2 ERIAFIGLGNMGNSMAKNLIAAGFDVVGFDADSRTNQRSAETGIPVAADVVDAVTGADVV 61
Query: 361 XSILTSNKVVLDVYLG---KDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTD 531
++L + ++ V LG + GV+ + G+L+IDSS+ID + A G+ F D
Sbjct: 62 ITMLPNGDILRQVLLGAGAESGVLNYLAPGALVIDSSSIDVANCLAVHESAASAGIAFLD 121
Query: 532 APVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLM 711
APVSGGV GA TL FM GG + R+ PL MG K G +G K+ N +
Sbjct: 122 APVSGGVGGAAAGTLTFMVGGDEAHVRRAWPLFEAMGKKVVRVGGPSTGQAVKMCNQMIY 181
Query: 712 GXPRLAXAD 738
+A A+
Sbjct: 182 ASSLVAVAE 190
>UniRef50_Q97XZ7 Cluster: Oxidoreductase; n=6; Thermoprotei|Rep:
Oxidoreductase - Sulfolobus solfataricus
Length = 289
Score = 113 bits (271), Expect = 7e-24
Identities = 62/175 (35%), Positives = 91/175 (52%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
V F+GLG MG MA+NL+K G+ + Y+ + + K G A+S S
Sbjct: 3 VGFIGLGIMGFPMASNLLKAGYDLTVYNRTIEKAEKLGKMGAKVAHSPKEVAEVSEIVIS 62
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
++T V +V G++GVV K+G + +D ST P K++ E G+ F DAPV+G
Sbjct: 63 MVTDAPDVEEVLFGENGVVKSNKRGLIFVDMSTNSPEFAKKVTKRLSEYGMEFLDAPVTG 122
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLM 711
G GA TL M GG+++ F+R P+ MG H G +GSG KL N ++
Sbjct: 123 GDKGAREGTLTIMVGGKEDVFKRVEPIFKAMGKNIIHVGDVGSGQALKLCNQVVV 177
>UniRef50_Q58PL4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
uncultured proteobacterium DelRiverFos06H03|Rep:
3-hydroxyisobutyrate dehydrogenase - uncultured
proteobacterium DelRiverFos06H03
Length = 299
Score = 112 bits (270), Expect = 9e-24
Identities = 63/172 (36%), Positives = 91/172 (52%)
Frame = +1
Query: 193 FLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSIL 372
F+G+GNMG MAANLVK G+ V +D S+ G T S+ + L
Sbjct: 10 FIGVGNMGNPMAANLVKAGYPVTVFDVSRAKAENLIALGATWVGSLAEGAVNADVVMASL 69
Query: 373 TSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGV 552
V +V LG+ GV+AH K G+ +ID+ST + +++ +A KG+ F +APV+ V
Sbjct: 70 PGPVQVREVMLGEQGVLAHVKAGATVIDTSTSAVELVQELVALAKSKGVDFLEAPVTNAV 129
Query: 553 MGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXL 708
A L+ GG K+ FE+ P+ V+G K FH G+ G+G KL N L
Sbjct: 130 DMAALGRLSIFVGGDKDCFEKHKPIFDVIGEKIFHVGEPGNGATIKLLTNLL 181
>UniRef50_Q67QX0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: 3-hydroxyisobutyrate
dehydrogenase - Symbiobacterium thermophilum
Length = 294
Score = 112 bits (269), Expect = 1e-23
Identities = 70/190 (36%), Positives = 93/190 (48%)
Frame = +1
Query: 184 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 363
N+ F+GLG MG MA NL++ G TV Y+ S+ ++ G A
Sbjct: 4 NLGFIGLGRMGRHMARNLIRAGHTVTLYNRSQAVVDELVAEGGRRAAGPAEVARDARVLF 63
Query: 364 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 543
+ LT+ VV + + A+ G + +D STI K+I + EKG+ F DAPVS
Sbjct: 64 TCLTTPDVVESILRQ---ALEGAQPGDIFVDHSTIGVRDAKRIAAMCAEKGVQFIDAPVS 120
Query: 544 GGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPR 723
GG GA TL M GG + FE LP L V G H G +G+G VAKL NN L+G
Sbjct: 121 GGPWGAEAGTLTIMCGGDRAAFEAVLPYLQVEGKAIHHLGPVGAGSVAKLCNNLLVGIHT 180
Query: 724 LAXADCXXHG 753
A A+ G
Sbjct: 181 AAMAEAFVLG 190
>UniRef50_Q183P5 Cluster: 2-hydroxy-3-oxopropionate reductase; n=5;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Clostridium difficile (strain 630)
Length = 296
Score = 111 bits (267), Expect = 2e-23
Identities = 63/175 (36%), Positives = 94/175 (53%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ F+GLG MG MA NL+K G + YD +K A++ G A S+ +
Sbjct: 3 LGFIGLGIMGKPMAKNLLKDGCNLLVYDINKSAVDELISCGAKYA-SVLEMGQECDIVFT 61
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
IL + +V D+ G DG+ K+GS+++D S++ P + GL F D+PVSG
Sbjct: 62 ILPNGTIVQDILFGMDGLAKTLKEGSIVVDMSSVTPTESILCANKLKDMGLEFIDSPVSG 121
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLM 711
G A + TLAFMAGG++E +++ P +MG+ G GSG V KLTN ++
Sbjct: 122 GEPKAIDGTLAFMAGGKEEIYKKVEPFFNIMGSSSILIGDNGSGSVTKLTNQVIV 176
>UniRef50_A6SW62 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Janthinobacterium sp. Marseille|Rep:
3-hydroxyisobutyrate dehydrogenase - Janthinobacterium
sp. (strain Marseille) (Minibacterium massiliensis)
Length = 298
Score = 111 bits (266), Expect = 3e-23
Identities = 66/177 (37%), Positives = 88/177 (49%), Gaps = 1/177 (0%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNA-AAKNGVTPANSIXXXXXXXXX 357
+N+ F+G+GNMG MA L +KGF++ YD NA A ++G A S
Sbjct: 5 RNIGFIGIGNMGAPMAGQLARKGFSLTVYDTHATTANAFAQEHGARVARSAAEVGIGADA 64
Query: 358 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 537
+L S++VV V L DG+ GS+ ID T P V + I G+G+ DAP
Sbjct: 65 VIFMLPSDQVVRQV-LFTDGLATQLAPGSIAIDMGTSAPAVTRSISAELATLGIGYLDAP 123
Query: 538 VSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXL 708
V GGV+ A +A+L M G ER PL MG K + CG IGS V K N +
Sbjct: 124 VMGGVVFAKDASLDIMVSGDDASIERCRPLFDAMGRKLWPCGDIGSAHVLKAMTNYI 180
>UniRef50_A3SJ77 Cluster: Probable oxidoreductase; n=1; Roseovarius
nubinhibens ISM|Rep: Probable oxidoreductase -
Roseovarius nubinhibens ISM
Length = 320
Score = 110 bits (264), Expect = 5e-23
Identities = 67/176 (38%), Positives = 83/176 (47%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
+ VAF+GLG MG MAA LV G VRG D L A + G PA S+
Sbjct: 12 RRVAFIGLGTMGSGMAARLVAAGHEVRGVDIDSARLAAFEEVGGLPAASVAEACDGAEII 71
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 540
+IL + V + LG G+ A G+L+I+ STI P I KGL DAPV
Sbjct: 72 MTILPRDTHVRQICLGAGGIADSAAPGTLVIEMSTISPEASLDIHDALTSKGLRVLDAPV 131
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXL 708
A N L MAGGR EDF + P+ + K H G GSG K+ NN +
Sbjct: 132 GRTPKDAQNGALLIMAGGRAEDFADAAPVFAPLADKIVHLGPKGSGIRMKIANNYM 187
>UniRef50_Q1QWQ5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Chromohalobacter salexigens
(strain DSM 3043 / ATCC BAA-138 / NCIMB13768)
Length = 315
Score = 109 bits (261), Expect = 1e-22
Identities = 65/189 (34%), Positives = 94/189 (49%)
Frame = +1
Query: 145 TAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPAN 324
T AR + +G G MG MA L + G+ VR ++ S D A +G+ A+
Sbjct: 13 TTAREDRDMQDTTTIGVIGTGLMGAPMARRLAEAGYAVRAWNRSNDKARALTAHGIDIAD 72
Query: 325 SIXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIA 504
S +L+S V D+ LG +GV+AH + L+ S+I + ++ A
Sbjct: 73 S-PRDAAGADIVVVMLSSGPVCDDILLGPEGVIAHMAPHATLVVMSSIPVDTAQRQAQAA 131
Query: 505 LEKGLGFTDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXV 684
+G+G+ DAPVSGG GA + TLA M GG FER PL +G + H G GSG +
Sbjct: 132 EARGIGYLDAPVSGGERGAIDGTLAIMVGGDPATFERHRPLFAPLG-RAVHVGPAGSGQL 190
Query: 685 AKLTNNXLM 711
AKL N ++
Sbjct: 191 AKLANQSIV 199
>UniRef50_P0ABQ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=25;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Escherichia coli O6
Length = 294
Score = 108 bits (260), Expect = 2e-22
Identities = 60/175 (34%), Positives = 95/175 (54%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
V F+GLG MG M+ NL+K G+++ D + +A+ G A++ +
Sbjct: 3 VGFIGLGIMGKPMSKNLLKAGYSLVVADRNPEAIADVIAAGAETASTAKAIAEQCDVIIT 62
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+L ++ V +V LG++G++ AK G++LID S+I P ++I KG+ DAPVSG
Sbjct: 63 MLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLASREISEALKAKGIDMLDAPVSG 122
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLM 711
G A + TL+ M GG K F++ L+ M H G+IG+G V KL N ++
Sbjct: 123 GEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVVHTGEIGAGNVTKLANQVIV 177
>UniRef50_A6LT11 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Clostridiales|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Clostridium beijerinckii
NCIMB 8052
Length = 291
Score = 108 bits (259), Expect = 2e-22
Identities = 59/173 (34%), Positives = 94/173 (54%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
K + F+G+G MG M NL+KKG+ V Y +K+ + G + +
Sbjct: 2 KTIGFIGVGVMGKSMVRNLMKKGYEVSIYTRTKEKVLDVINEGAKWCDDVKSCANNRDVI 61
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 540
+I+ K V +VY G++G++ +AKK S +ID +T P + +I+ A ++ + DAPV
Sbjct: 62 ITIVGYPKDVEEVYFGENGILENAKKESCIIDMTTTSPKLSIKIYNEAKKREIYALDAPV 121
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTN 699
SGG +GA NATL+ M GG E FE+ +L +G + G+ G+G K+ N
Sbjct: 122 SGGDVGAKNATLSIMVGGDLEVFEKHKDVLSALGTNIIYEGKAGNGQHTKMAN 174
>UniRef50_Q01ZG6 Cluster: 2-hydroxy-3-oxopropionate reductase; n=6;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Solibacter usitatus (strain Ellin6076)
Length = 298
Score = 107 bits (258), Expect = 3e-22
Identities = 62/176 (35%), Positives = 91/176 (51%)
Frame = +1
Query: 184 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 363
++ F+GLG MG M+ NL+K G+++ YD + + G S
Sbjct: 3 DIGFIGLGIMGKPMSRNLMKAGYSLVVYDIFPGPVAELKEAGAGAGASCAATAAAAPIVI 62
Query: 364 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 543
++L V LG GV+ AK G++++D S+I P V +++ KG+ F DAPVS
Sbjct: 63 TMLPDGPEVETAVLGPGGVLEGAKAGTVVVDMSSISPMVSQKVAAACAAKGVEFLDAPVS 122
Query: 544 GGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLM 711
GG A + TLA M GG+ E FER P+L MGA G +G+G V KL N ++
Sbjct: 123 GGEPKAIDGTLAIMVGGKPEVFERVQPVLAKMGASVTLTGAVGAGNVTKLANQIMV 178
>UniRef50_Q92D17 Cluster: Lin1004 protein; n=10; Bacilli|Rep:
Lin1004 protein - Listeria innocua
Length = 286
Score = 106 bits (255), Expect = 6e-22
Identities = 59/173 (34%), Positives = 90/173 (52%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
+ + F+G G MG MA +L++ G+ V Y +K+ A G +
Sbjct: 2 EKIGFVGTGVMGSSMAKHLLEAGYEVHIYTRTKEKAEALLSQGALWESDPGSLGAKVDIL 61
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 540
S++ K V +YLG++G + + K GS+ ID +T P + K+I EKG+G DAPV
Sbjct: 62 ISMVGYPKDVEQLYLGENGFLDNLKAGSVAIDMTTSSPALAKKIAEAGHEKGIGVLDAPV 121
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTN 699
SGG +GA N TLA M GG ++ F + P+ ++G+ G GSG K+ N
Sbjct: 122 SGGDIGAKNGTLAIMVGGAEDVFLKVKPIFEILGSSVILQGDAGSGQHTKMVN 174
>UniRef50_A0GVR3 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia phytofirmans PsJN|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Burkholderia phytofirmans PsJN
Length = 311
Score = 106 bits (254), Expect = 8e-22
Identities = 60/174 (34%), Positives = 90/174 (51%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ F+G G MG M +NL+K V D ++DA + A G T A ++ +
Sbjct: 3 IGFIGAGRMGHRMISNLLKGSHAVLVLDGARDARDRVASLGATLAMNLADLVTGQDIVIT 62
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+L + V L VY G G+ + +LL++ ST+D +++ A G DAP++G
Sbjct: 63 MLPTPDVSLSVYEGAGGLFSITPPETLLLECSTVDVKTIERLGEGARASGTQLIDAPLTG 122
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXL 708
G+ GA ATL FM GG +E E + P L MG++ H G+ GSG KL NN +
Sbjct: 123 GIEGAALATLTFMVGGSEEQLEYARPALQSMGSRIVHAGRFGSGTKLKLVNNMI 176
>UniRef50_A0K0Z6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=2; Micrococcineae|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Arthrobacter sp. (strain FB24)
Length = 301
Score = 105 bits (251), Expect = 2e-21
Identities = 70/182 (38%), Positives = 93/182 (51%), Gaps = 3/182 (1%)
Frame = +1
Query: 172 NTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXX 351
NT +A +GLG MGG MAA L K G+ V G+DPS+ A AAA+ G+ S+
Sbjct: 2 NTSTRIAVIGLGAMGGAMAATLHKAGWDVTGFDPSEAARTAAAQTGIATTASLDDVAGTP 61
Query: 352 XXXXSILTSNKVVLDV--YLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGF 525
S+ ++ V V L G VA +ID++T +P KQ+ +A +G F
Sbjct: 62 YAVLSLPAASIVETTVPRLLAVPGTVA-------IIDTTTSEPATSKQMAHLADTQGAAF 114
Query: 526 TDAPVSGGVMGAXNATLAFMAGGRKEDFERSLP-LLXVMGAKQFHCGQIGSGXVAKLTNN 702
DAPVSGG GA + +L+ GG + P LL + G K H G GSG V KL NN
Sbjct: 115 VDAPVSGGRDGAASGSLSAFVGGTDAALAAAEPVLLALTGGKYSHIGGPGSGNVVKLLNN 174
Query: 703 XL 708
L
Sbjct: 175 VL 176
>UniRef50_UPI00015B4162 Cluster: PREDICTED: similar to MGC108315
protein; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to MGC108315 protein - Nasonia vitripennis
Length = 276
Score = 104 bits (250), Expect = 2e-21
Identities = 52/122 (42%), Positives = 73/122 (59%)
Frame = +1
Query: 139 LYTAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTP 318
+YT R NV F+GLGNMGGFMA NL+KKG+ + +D +K A++ G
Sbjct: 13 IYTVGR--VGQRDFSNVGFVGLGNMGGFMAKNLLKKGYKLTVFDINKTAIDNVVSAGAKG 70
Query: 319 ANSIXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFP 498
A S+ ++L N+ VLD Y GKDG+++ AKKG+ L+DSSTIDP+V + +F
Sbjct: 71 AESVAEVSQNSEVIVTMLPMNQHVLDTYTGKDGIISSAKKGTFLVDSSTIDPSVSQTVFK 130
Query: 499 IA 504
A
Sbjct: 131 AA 132
>UniRef50_Q12CU4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=17;
Proteobacteria|Rep: 2-hydroxy-3-oxopropionate reductase
- Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 298
Score = 104 bits (250), Expect = 2e-21
Identities = 64/178 (35%), Positives = 89/178 (50%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
+ + FLG G+MG MA L + G+ ++ ++ + + A G T
Sbjct: 10 RKITFLGTGSMGLPMARRLCEAGYALQVWNRTPARAASLAALGATIHEQARAAARDADIV 69
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 540
S+L + VV DV + GV A K GSL +D ++I P + G+ D PV
Sbjct: 70 VSMLENGAVVQDVLFAQ-GVAAAMKPGSLFLDMASITPREARDHAARLGALGIAHLDTPV 128
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMG 714
SGG +GA TL MAGG+ DFERSLPLL V G + H G GSG + KL N ++G
Sbjct: 129 SGGTVGAEQGTLVIMAGGKPADFERSLPLLKVFG-RATHVGPHGSGQLTKLANQMIVG 185
>UniRef50_Q0S5S3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 299
Score = 103 bits (248), Expect = 4e-21
Identities = 63/174 (36%), Positives = 87/174 (50%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
V F+GLGN+GG + A+LVK G V YD + A++AA G S
Sbjct: 5 VGFVGLGNIGGRVVAHLVKAGHDVAVYDLNTAAVDAAVALGARSVASPGEAARKAEALFL 64
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
L + +V V V+ +G +++D STIDP+ +++ A G F DAPVSG
Sbjct: 65 SLPTPAIVEGVVAD---VLQQGNQGLVIVDHSTIDPDTTRRLAQDAQVAGACFLDAPVSG 121
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXL 708
GV GA TLA M GG + ++ +PL+ FH G GSG KL NN +
Sbjct: 122 GVQGAEAGTLAVMLGGDEASVKKVIPLIETYAGNIFHVGPSGSGQAIKLANNQI 175
>UniRef50_Q03UI4 Cluster: 3-hydroxyisobutyrate dehydrogenase related
enzyme; n=2; Lactobacillales|Rep: 3-hydroxyisobutyrate
dehydrogenase related enzyme - Leuconostoc mesenteroides
subsp. mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 287
Score = 103 bits (248), Expect = 4e-21
Identities = 56/173 (32%), Positives = 90/173 (52%)
Frame = +1
Query: 184 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 363
N+ F+G G MG + NL++ G+ V ++ + N NG ++
Sbjct: 2 NIGFIGTGVMGTGIINNLLQAGYEVSVFNRTHSKANTVLNNGAIWRDTPAKVAQYSDITF 61
Query: 364 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 543
+++ K V +V+ +DGV A AK+GS+L+D +T P + +Q+ + G DAPVS
Sbjct: 62 TMVGYPKDVEEVWTSEDGVFAGAKEGSILVDMTTSTPRLAEQLAQTGADLGFKVLDAPVS 121
Query: 544 GGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNN 702
GG +GA N TLA M GG ++ + P+L V+G + G G G K++NN
Sbjct: 122 GGDIGAKNGTLAIMVGGEQQVLDEIKPVLSVIGQQIVFAGSAGKGQHMKMSNN 174
>UniRef50_Q5WBB8 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Bacillus clausii KSM-K16|Rep: 3-hydroxyisobutyrate
dehydrogenase - Bacillus clausii (strain KSM-K16)
Length = 283
Score = 102 bits (245), Expect = 1e-20
Identities = 60/177 (33%), Positives = 80/177 (45%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
K V +G G MG MA +L+ G+TV YD K G +
Sbjct: 2 KTVGLIGCGAMGKGMATSLLSAGYTVYIYDDMSKWREPLEKQGACFVENSAAVAKKAKYV 61
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 540
L S +V D GK+GV+ H + G L+D ST D + A KG+ + D PV
Sbjct: 62 LLSLPSPNIVADTVAGKEGVLCHLQTGGFLLDLSTTDVQTTLAMEKAAAAKGIYYLDCPV 121
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLM 711
SGG GA TL M GG K+ + PLL ++G + G G+G KL NN L+
Sbjct: 122 SGGPAGADAGTLTIMVGGDKQAYFSVKPLLDILGDTILYVGDSGAGQTVKLCNNMLV 178
>UniRef50_A6GTB5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein; n=1; Limnobacter sp. MED105|Rep:
6-phosphogluconate dehydrogenase, NAD-binding protein -
Limnobacter sp. MED105
Length = 299
Score = 102 bits (244), Expect = 1e-20
Identities = 60/175 (34%), Positives = 82/175 (46%)
Frame = +1
Query: 175 TDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXX 354
T + F+GLGNMG MA +L K G+TV + + A A + P SI
Sbjct: 7 TLNTIGFIGLGNMGAAMAGHLCKAGYTVLAWARNASTFEALADIPLVPQPSIEALCASTR 66
Query: 355 XXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 534
+T+ V + G+ HA+ GS+++D STID I +G+ + D
Sbjct: 67 LVALNVTNTADVQSLLFRDGGIAQHAQPGSIIVDFSTIDAAAVADIARQLKSRGVDYIDC 126
Query: 535 PVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTN 699
PVSGG GA ATL+ MAGG F R P+L +G H G G+G K N
Sbjct: 127 PVSGGAAGARAATLSMMAGGDLAAFNRIEPMLKHLGKTIRHVGPSGAGQAIKAAN 181
>UniRef50_Q2JEV5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=6; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Frankia sp. (strain CcI3)
Length = 302
Score = 101 bits (243), Expect = 2e-20
Identities = 60/176 (34%), Positives = 91/176 (51%), Gaps = 1/176 (0%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYD-PSKDALNAAAKNGVTPANSIXXXXXXXXXXX 363
VAF+GLG MG MA +LV+ GF+ ++ + A A ++ A S
Sbjct: 3 VAFVGLGTMGFPMAGHLVRAGFSTTAFNRTAATAARWAEEHSGRIAPSPAAAATEVDVVC 62
Query: 364 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 543
+ ++ V +V LG DGV+ + G++++D +T + ++I E G+GF DAPVS
Sbjct: 63 LCVGADDDVREVVLGADGVLGALRPGAIIVDHTTTSAELAEEIAARTAEVGVGFVDAPVS 122
Query: 544 GGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLM 711
GG GA L+ M GG E ER+ P+L GA G +GSG + K+ N L+
Sbjct: 123 GGEAGAMAGRLSIMCGGDPETIERARPVLAAYGATITRIGPVGSGQLTKMVNQILV 178
>UniRef50_Q1GJB9 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding; n=1; Silicibacter sp. TM1040|Rep:
6-phosphogluconate dehydrogenase NAD-binding -
Silicibacter sp. (strain TM1040)
Length = 304
Score = 101 bits (243), Expect = 2e-20
Identities = 65/180 (36%), Positives = 91/180 (50%), Gaps = 2/180 (1%)
Frame = +1
Query: 178 DKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGV-TPANSIXXXXXXXX 354
+K +GLG MG MA +L+K GF V GYDP++ A AA GV A++
Sbjct: 6 NKRAGVIGLGAMGLGMARSLLKAGFAVSGYDPAETARENAAAAGVWLTADTDAVFADCDV 65
Query: 355 XXXSILTSNKVVLDVYLGKD-GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTD 531
S+ T+ V+ V + G +A +++D+ST + + + G GF D
Sbjct: 66 IVLSLPTAQHVLAVVQAAQAAGHLAQTGAARVIVDTSTSEAATSRTLAAELSALGHGFLD 125
Query: 532 APVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLM 711
APVSGG GA + L+ M GG + E + P L M AK H G G+G VAKL NN L+
Sbjct: 126 APVSGGPAGAASGQLSVMLGGETQWLEAARPALEAMAAKILHVGPSGAGNVAKLVNNMLV 185
>UniRef50_A1UP64 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mycobacterium sp. (strain
KMS)
Length = 305
Score = 101 bits (242), Expect = 2e-20
Identities = 61/176 (34%), Positives = 85/176 (48%)
Frame = +1
Query: 184 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 363
NV F+GLG MG MA +LV G V ++ S+ ++ G A S
Sbjct: 2 NVGFIGLGVMGKPMAGHLVDAGHHVVVFNRSRAKVDELEARGAVGATSPAHAGEKADVVI 61
Query: 364 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 543
++L + V +V G GV + GSL+ID STI P+ I EK + F DAPVS
Sbjct: 62 TMLPDSPEVEEVLFGPAGVTTTLRPGSLVIDCSTISPDAAVAIGARLAEKDIAFVDAPVS 121
Query: 544 GGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLM 711
GG GA LA M GG ++ R+ +L + A H G +G+G + K N L+
Sbjct: 122 GGEAGAIAGALAVMMGGDEDAVRRAATVLDAVAATSVHVGPVGAGQLVKAANQMLV 177
>UniRef50_Q7WCG3 Cluster: Putative uncharacterized protein; n=2;
Bordetella|Rep: Putative uncharacterized protein -
Bordetella parapertussis
Length = 296
Score = 101 bits (241), Expect = 3e-20
Identities = 62/178 (34%), Positives = 87/178 (48%), Gaps = 2/178 (1%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
K VAF+G+GNMG MA + GF + D + D L A A+ GV SI
Sbjct: 5 KTVAFIGVGNMGAPMARCARRAGFELIVCDRNPDVLAAFAQEGVRVTASISDCAAADAVV 64
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKGS--LLIDSSTIDPNVPKQIFPIALEKGLGFTDA 534
+L ++ +++ LG G+ G ++ ST P+ + + G DA
Sbjct: 65 V-LLANDAQIMETMLGGQGLAQAVPAGHRPIVCMMSTTLPDTLRALEAPLAAVGARLVDA 123
Query: 535 PVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXL 708
PVSGG++GA TL M GG D E PL+ MG + FHCG +GS +AK+ NN L
Sbjct: 124 PVSGGIVGAEAGTLTIMMGGETADVEAVRPLMQAMGERLFHCGALGSAEIAKVINNML 181
>UniRef50_A0LTQ8 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=1; Acidothermus cellulolyticus
11B|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
precursor - Acidothermus cellulolyticus (strain ATCC
43068 / 11B)
Length = 305
Score = 101 bits (241), Expect = 3e-20
Identities = 65/189 (34%), Positives = 92/189 (48%), Gaps = 5/189 (2%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNA-----AAKNGVTPANSIXXXXXXX 351
VA LGLG MG MAA L G + ++ +++ A AK TPA ++
Sbjct: 4 VAVLGLGAMGSAMAARLHDAGAELILWNRTRERAQALGERLGAKVAATPAEAVADVPVAL 63
Query: 352 XXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTD 531
+ L + V DV+LG DGVVA A+ G ++ + ST++P V + I P KG D
Sbjct: 64 ----TSLADRRAVEDVFLGPDGVVAGARPGLVVAELSTVEPEVARAIAPELRAKGADILD 119
Query: 532 APVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLM 711
PVSG V A L M GG + P+L ++G + FH G +GSG KL N ++
Sbjct: 120 VPVSGSVAVAREGGLTLMVGGEDASLDAIRPVLDIIGRRIFHLGPLGSGAAMKLAVNTVI 179
Query: 712 GXPRLAXAD 738
A A+
Sbjct: 180 HGLNAALAE 188
>UniRef50_Q4Q7T9 Cluster: 2-hydroxy-3-oxopropionate reductase,
putative; n=6; Trypanosomatidae|Rep:
2-hydroxy-3-oxopropionate reductase, putative -
Leishmania major
Length = 299
Score = 100 bits (240), Expect = 4e-20
Identities = 60/185 (32%), Positives = 93/185 (50%), Gaps = 1/185 (0%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
V ++GLG MG MA N++K GF V ++ + + G T + +
Sbjct: 3 VGYIGLGLMGKPMAVNILKAGFPVSVWNRTASKCDDLVAAGATACATPAELAAASDVVFT 62
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFP-IALEKGLGFTDAPVS 543
L+ + V++V G +GV A +G++ +D+STI P+V ++I + EK + DAPVS
Sbjct: 63 NLSDSPDVMEVVFGPNGVAAGICEGAIFVDNSTIKPSVAQEIARRLWKEKKVRALDAPVS 122
Query: 544 GGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPR 723
GG +GA N TL M GG LP+L +G K H G G+G V K N ++
Sbjct: 123 GGDIGARNGTLTVMVGGDAAALATVLPVLLAVGKKVTHIGDCGAGQVCKAANQIMVAAQM 182
Query: 724 LAXAD 738
+A +
Sbjct: 183 VALGE 187
>UniRef50_Q5L168 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=15;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Geobacillus kaustophilus
Length = 288
Score = 99 bits (238), Expect = 7e-20
Identities = 53/173 (30%), Positives = 88/173 (50%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
K + F+GLG MG MA +L+K G+ + Y +K+ + G ++
Sbjct: 2 KTIGFIGLGVMGKSMARHLLKAGYPLLAYTRTKEKAEDLLQEGAVWKETVADLAREADVV 61
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 540
+++ + V VY G+ G++ +A+ G+ +ID +T P + + I+ A +KG+ DAPV
Sbjct: 62 MTMVGDPRDVEQVYFGEGGILENARPGTYVIDMTTSTPTLAQSIYEAAKQKGIHALDAPV 121
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTN 699
SGG +GA TL M GG ++ F P+L +G G G+G K+ N
Sbjct: 122 SGGDIGAREGTLTIMVGGDEDVFLACKPILERLGTNIVRQGGAGAGQHTKMCN 174
>UniRef50_Q1YHQ4 Cluster: Putative 2-hydroxy-3-oxopropionate
reductase; n=1; Aurantimonas sp. SI85-9A1|Rep: Putative
2-hydroxy-3-oxopropionate reductase - Aurantimonas sp.
SI85-9A1
Length = 292
Score = 99 bits (238), Expect = 7e-20
Identities = 63/175 (36%), Positives = 86/175 (49%), Gaps = 1/175 (0%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ F+GLG MG L + + V G+D + ++AAA GV PA S+
Sbjct: 4 IGFIGLGLMGSGFTKRLRELDYRVIGHDREAEKVSAAAAWGVEPAGSLAALCAEADIIAL 63
Query: 367 ILTSNKVVLDVYLGKDGVVAHAK-KGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 543
LT++ V V G DG+VA K G ++D ST + V Q+ G F DAPVS
Sbjct: 64 CLTTSDAVASVVTGADGLVASRKLSGRTVVDFSTTEMAVTHQVAAAIEAVGGRFVDAPVS 123
Query: 544 GGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXL 708
GG A TLA M GG ++ E + P+L +G + H G IG+G KL N L
Sbjct: 124 GGPGAAETGTLAIMFGGSEQAAEAARPMLEQLG-RATHMGAIGTGQATKLVNQVL 177
>UniRef50_A0C2T7 Cluster: Chromosome undetermined scaffold_145,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_145,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 299
Score = 99 bits (238), Expect = 7e-20
Identities = 62/189 (32%), Positives = 93/189 (49%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ F+GLGNMG MA NL K V YD S + + + P N + +
Sbjct: 14 IGFIGLGNMGIGMAHNLAKTR-VVYAYDVSPAWQSNIESSNIKPVNQVADVAANADTIIT 72
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+L ++K+V V + +KK +LIDSSTI P ++ +A + + DAPVSG
Sbjct: 73 MLPNDKIVKSV---AQEIFKKSKK--ILIDSSTISPYTSYELAKMAQDTQNIYADAPVSG 127
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPRL 726
V A T+ FM G KE +E+ P+L MG F+CG+IG G +AK+ N + +
Sbjct: 128 SVSEAKLGTITFMVGAEKELYEKISPILKEMGKNIFNCGKIGEGQIAKMCGNMALAIQMI 187
Query: 727 AXADCXXHG 753
+ + G
Sbjct: 188 SVCEALALG 196
>UniRef50_Q9L7S0 Cluster: Uncharacterized oxidoreductase yihU; n=24;
Gammaproteobacteria|Rep: Uncharacterized oxidoreductase
yihU - Salmonella typhimurium
Length = 298
Score = 99 bits (238), Expect = 7e-20
Identities = 57/174 (32%), Positives = 83/174 (47%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+AF+GLG MG MA+NL+K+G + +D + DA+ G PA+S +
Sbjct: 4 IAFIGLGQMGSPMASNLLKQGHQLSVFDVNPDAVQRLVDKGAQPASSPAQATIGAEFVIT 63
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+L + +V V G+ GV + +L+ID STI P + KG D P+
Sbjct: 64 MLPNGDLVRSVLFGEQGVCETLSREALVIDMSTIHPLQTDNLIADMQSKGFSMMDVPIGR 123
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXL 708
A TL +AGG E ER+ P+L MG + + G G G KL NN +
Sbjct: 124 TSDNAITGTLLLLAGGTAEQVERATPVLMAMGNELVNTGGPGMGIRVKLINNYM 177
>UniRef50_Q4KH51 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=16; Gammaproteobacteria|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477)
Length = 298
Score = 99.5 bits (237), Expect = 9e-20
Identities = 62/190 (32%), Positives = 95/190 (50%), Gaps = 5/190 (2%)
Frame = +1
Query: 184 NVAFLGLGNMGGFMAANLVKKGF--TVRGYDPSKDA--LNAAAKNGVTPANSIXXXXXXX 351
++ F G+G MG M L+ G+ TV +P K A + A A+ TPA
Sbjct: 7 SLGFAGIGLMGLPMCRRLLAAGYPLTVWNRNPEKCAPLVAAGARQVATPAQ----LCADA 62
Query: 352 XXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFP-IALEKGLGFT 528
L + +VV +V G G+ A+ G LL+D S+++P +++ +A +G+ +
Sbjct: 63 DLMLMCLANTEVVREVVFGPQGIAQGARAGQLLLDLSSLEPTATREMAAELAASRGVAWV 122
Query: 529 DAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXL 708
DAPVSGG GA +LA M GG D ER P+L +G + H G +G+G V K N +
Sbjct: 123 DAPVSGGTPGAEAGSLAIMVGGEATDVERVRPVLLTLGQRVTHMGAVGAGQVTKACNQMI 182
Query: 709 MGXPRLAXAD 738
+ L A+
Sbjct: 183 VACNALVIAE 192
>UniRef50_A0N0V2 Cluster: BtdhL; n=1; Azoarcus anaerobius|Rep: BtdhL
- Azoarcus anaerobius
Length = 303
Score = 99.5 bits (237), Expect = 9e-20
Identities = 57/179 (31%), Positives = 86/179 (48%)
Frame = +1
Query: 178 DKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXX 357
D V ++GLG MG MAANL+ G + Y+ S +A + G A S+
Sbjct: 6 DTRVGWIGLGKMGTPMAANLLAAGHAITVYNRSAARADALVEKGAALAPSVAALARDCAI 65
Query: 358 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 537
S+++ + + + L GV A G + ID ST+ P + ++I A KG+ + AP
Sbjct: 66 VISMVSDDAALQGITLDAGGVFEAATPGMVFIDMSTVSPALSERIAAAASAKGIHYLRAP 125
Query: 538 VSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMG 714
VSG A L +A G K+ +ER LPLL MG K ++ G K+ N ++G
Sbjct: 126 VSGSTTTAAAGALTILASGPKDAYERCLPLLQAMGKKLYYLGPAEQARYLKVAINMMLG 184
>UniRef50_A0LMG6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Syntrophobacter fumaroxidans (strain DSM
10017 / MPOB)
Length = 309
Score = 99.5 bits (237), Expect = 9e-20
Identities = 54/189 (28%), Positives = 99/189 (52%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ ++G G MG M ++++KG+ ++ ++ ++G A+S +
Sbjct: 16 IGWIGTGVMGLSMCGHVMRKGYATSVHNRTRHKAAPLVESGAGWADSPRQVAEQSDVVFT 75
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+L + V +VY G++G++ A+ G +L+D +T +P++ ++I A E+G DAPVSG
Sbjct: 76 MLGFPQDVREVYFGRNGLLQAARPGIILVDMTTTEPSLAREIHQAAGEQGAFAVDAPVSG 135
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPRL 726
G +GA NA L+ M GG +E + P+L MG + G GSG AK+ N ++ +
Sbjct: 136 GDVGARNAALSIMLGGDREVVDAIRPILEAMGKNLVYLGPAGSGQHAKVCNQIVITGTMI 195
Query: 727 AXADCXXHG 753
+ +G
Sbjct: 196 GVCESLMYG 204
>UniRef50_A2U9T6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Bacillaceae|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Bacillus coagulans 36D1
Length = 294
Score = 99.1 bits (236), Expect = 1e-19
Identities = 58/176 (32%), Positives = 87/176 (49%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ ++GLG+MG MA L+ F + Y+ + A+ G + +
Sbjct: 8 IGWIGLGHMGSPMARRLLDAHFDLFVYNRTIKKTEKLAEAGAAVCKTPKDIAENADVIVT 67
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+LT+ V +V G+DGV+A KG ++D ST+ P+ + EK F DAPVSG
Sbjct: 68 MLTNAAAVENVLQGEDGVLAGLTKGKTVVDMSTVSPSDSIRFAKWVEEKRGHFIDAPVSG 127
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMG 714
V A L +AGGRKE+ + P+ V+G H G+ G G AKL+ N L+G
Sbjct: 128 SVQPAKEGNLVILAGGRKEEIDAVRPMFEVLGKTIIHFGENGKGSAAKLSINLLLG 183
>UniRef50_Q7WG50 Cluster: Probable oxidoreductase; n=1; Bordetella
bronchiseptica|Rep: Probable oxidoreductase - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 316
Score = 98.7 bits (235), Expect = 2e-19
Identities = 61/174 (35%), Positives = 83/174 (47%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+AFLGLG MG MA NLVK G V GYD + AL+A A+ G A S +
Sbjct: 6 IAFLGLGAMGLPMACNLVKGGHAVTGYDLNPQALDALAQAGGQRAASAREAAAGAALVIA 65
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+L + + G DG + G+L I+ STI P I E+G+ D+PV
Sbjct: 66 MLPTATHIQAALEGADGALQGMDPGALFINMSTILPQETDLIAQRLAERGMRMLDSPVGR 125
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXL 708
M A TL +A G +D R+ L MG + CG++G G K+ NN +
Sbjct: 126 SAMEAQRGTLLILASGSAQDKARARDALLCMGNQVIDCGEVGGGSRVKVVNNFM 179
>UniRef50_A3VLN6 Cluster: Oxidoreductase; n=1; Rhodobacterales
bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales
bacterium HTCC2654
Length = 293
Score = 98.7 bits (235), Expect = 2e-19
Identities = 58/175 (33%), Positives = 84/175 (48%), Gaps = 1/175 (0%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
V F GLGN+G MA L ++G + ++ S+ + GV A S
Sbjct: 3 VGFAGLGNIGALMAWRLQERGHDLVVWNRSQAKTQSFRDAGVPVAPSPADLARQVDVLCL 62
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFP-IALEKGLGFTDAPVS 543
+T K + V G DG+V + ++++D ST+ P+ +QI + E G + DAPVS
Sbjct: 63 CVTDAKALDAVLFGSDGIVGAGRVPAMIVDHSTVPPDATRQIAARVRAEAGAAWVDAPVS 122
Query: 544 GGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXL 708
GG+ GA LA GG D R+ P+L +G H G GSG VAK N +
Sbjct: 123 GGLAGAAAGQLAIFVGGEDADVTRAWPVLTTLGTTVTHLGPTGSGQVAKACNQVI 177
>UniRef50_Q89HA0 Cluster: Oxidoreductase; n=1; Bradyrhizobium
japonicum|Rep: Oxidoreductase - Bradyrhizobium japonicum
Length = 313
Score = 97.9 bits (233), Expect = 3e-19
Identities = 59/188 (31%), Positives = 86/188 (45%), Gaps = 1/188 (0%)
Frame = +1
Query: 178 DKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXX 357
D+ +LGLG MG M L+K G+ V ++ S+ + + G S
Sbjct: 23 DERFGYLGLGLMGTPMTRRLLKAGYQVSVWNRSEGKVVPIVEAGARHGASPRDVMAGSDI 82
Query: 358 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFP-IALEKGLGFTDA 534
+T V +V G +G+ G L++D S+I P+ + + + G G+ DA
Sbjct: 83 VFMCVTDAAAVEEVIFGAEGLSTAPGAGKLVVDFSSIHPDAARDLATRLKAANGAGWIDA 142
Query: 535 PVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMG 714
PVSGG GA TLA MAGG D ER P + M + H G G+G AKL N ++G
Sbjct: 143 PVSGGTKGAEEGTLAIMAGGDASDIERVRPYVLTMARRFTHMGPTGAGQTAKLCNQVIVG 202
Query: 715 XPRLAXAD 738
A+
Sbjct: 203 CAMAVLAE 210
>UniRef50_Q94B07 Cluster: Gamma hydroxybutyrate dehydrogenase; n=16;
cellular organisms|Rep: Gamma hydroxybutyrate
dehydrogenase - Arabidopsis thaliana (Mouse-ear cress)
Length = 289
Score = 97.5 bits (232), Expect = 4e-19
Identities = 58/176 (32%), Positives = 84/176 (47%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
V FLGLG MG M+ NL+K GF V ++ + + ++G + S +
Sbjct: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+L+ L V K GV+ +G ID ST+D +I KG F + PVSG
Sbjct: 63 MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSG 122
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMG 714
A + L +A G K FE S+P V+G + F+ GQ+G+G KL N +MG
Sbjct: 123 SKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMG 178
>UniRef50_Q89R44 Cluster: Oxidoreductase; n=23; Bacteria|Rep:
Oxidoreductase - Bradyrhizobium japonicum
Length = 305
Score = 97.1 bits (231), Expect = 5e-19
Identities = 57/184 (30%), Positives = 88/184 (47%), Gaps = 1/184 (0%)
Frame = +1
Query: 166 SSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXX 345
S++ ++ +A +GLG+MG MA +L + G V G D S DA+ K+G A +
Sbjct: 4 STSQNQRIAVVGLGSMGFGMATSLKRAGHAVTGCDVSADAVARFVKDGGAGAKTPAEAAR 63
Query: 346 XXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGF 525
S++ + + GKDGV K S+ + S+T+DP+V +++ G +
Sbjct: 64 GADVVVSVVVNAAQTETILFGKDGVAETMPKDSVFLSSATMDPDVARRLAKQLEATGRHY 123
Query: 526 TDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQ-IGSGXVAKLTNN 702
DAP+SGG A L +A G F ++ P L M AK + G G G K+ N
Sbjct: 124 LDAPISGGAQRAAQGELTILASGSPAAFAKARPALDAMAAKLYELGDAAGQGAAFKMINQ 183
Query: 703 XLMG 714
L G
Sbjct: 184 LLAG 187
>UniRef50_A5USN9 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Roseiflexus|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Roseiflexus sp. RS-1
Length = 302
Score = 97.1 bits (231), Expect = 5e-19
Identities = 57/177 (32%), Positives = 84/177 (47%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
+ + F+GLG MG MA L+ GF + ++ ++ A G A +
Sbjct: 2 ERLGFIGLGRMGQVMAGRLLAAGFPLTVHNRTRARAEALLAGGAAWAETPAEVTARSDLV 61
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 540
+ILT + V VY G+DG+++ G L I+ STI + + + ++G DAPV
Sbjct: 62 FTILTDDHAVETVYCGRDGLLSTDASGRLFIEMSTIRTSTILSLAGMVDQRGARLLDAPV 121
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLM 711
SG V A L + GGR D ER+ P L V+G + H G G+G KL N M
Sbjct: 122 SGTVAPAREGQLLVLVGGRTSDLERARPALGVLGRRIIHLGGQGAGTTMKLVLNMTM 178
>UniRef50_A1B741 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Paracoccus denitrificans (strain Pd 1222)
Length = 309
Score = 97.1 bits (231), Expect = 5e-19
Identities = 61/172 (35%), Positives = 84/172 (48%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ F+GLG MG MAANL G + D S+ A G T A + +
Sbjct: 3 IGFIGLGKMGRGMAANLQTGGAALVVADLSRTAAEEFTVRGATWAETPADLARDCGIVFT 62
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
L + V + G G+V G++ +D ST +V +QI KG+ F DAPVSG
Sbjct: 63 SLPTPADVRNAGFGPRGLVEGMAPGTVWLDLSTNSVDVVRQIHAELAPKGIHFIDAPVSG 122
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNN 702
G GA + LA GG +E ++R LP L M + + G IG+G +AKL NN
Sbjct: 123 GPAGAASGQLAIWCGGEREVYDRCLPWLEKMADQPRYIGDIGAGTIAKLVNN 174
>UniRef50_Q89UN2 Cluster: Bll1384 protein; n=9; Bacteria|Rep:
Bll1384 protein - Bradyrhizobium japonicum
Length = 356
Score = 96.3 bits (229), Expect = 9e-19
Identities = 61/204 (29%), Positives = 96/204 (47%)
Frame = +1
Query: 142 YTAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPA 321
++ +R ++ ++ F+GLGNMG MA L++ G + +D K+ ++ G TPA
Sbjct: 42 FSRQQRIINTRNTMDIGFIGLGNMGFPMARRLIEAGNRLVVFDTRKEVVDKLVARGATPA 101
Query: 322 NSIXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPI 501
S + L S + L+V G +GV+ + ID ST+ + +I +
Sbjct: 102 TSPKDVADQVETVMASLPSLQASLEVATGTNGVI-EGSRVKRFIDLSTVGSTMASKIHGL 160
Query: 502 ALEKGLGFTDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGX 681
++ + D PVSGGV GA TLA M G K +FE P L V+G F + G+
Sbjct: 161 LAKRDIVQIDCPVSGGVGGAEKGTLAVMVSGPKAEFELLKPALDVIGKVFFIGEKPGAAQ 220
Query: 682 VAKLTNNXLMGXPRLAXADCXXHG 753
KL NN L +A ++ G
Sbjct: 221 TMKLANNFLSATAIVATSEAVVMG 244
>UniRef50_A6SUL3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Janthinobacterium sp. Marseille|Rep:
2-hydroxy-3-oxopropionate reductase - Janthinobacterium
sp. (strain Marseille) (Minibacterium massiliensis)
Length = 304
Score = 96.3 bits (229), Expect = 9e-19
Identities = 57/176 (32%), Positives = 92/176 (52%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+AFLG+G MG MA+ L++ G+ V ++ ++ + A G + A + +
Sbjct: 10 IAFLGIGLMGKPMASRLLQAGYPVTAWNRTRSKADELAPLGASVAERVADAVAAADIVIT 69
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+L + +V V D + K G+L+ID S+ + +++ +G+ F DAPVSG
Sbjct: 70 MLEAGPIVAQVI---DAALPGLKHGALVIDMSSTRQSEAQEVHAKLAAQGVRFIDAPVSG 126
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMG 714
GV+GA +LA MAGG +DF + +L VMG G G G +AKL N ++G
Sbjct: 127 GVVGAEAGSLAIMAGGSAQDFAEAEAVLTVMGRPTL-VGPAGCGQIAKLCNQLIVG 181
>UniRef50_Q0F1Y7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein; n=1; Mariprofundus ferrooxydans
PV-1|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
protein - Mariprofundus ferrooxydans PV-1
Length = 289
Score = 95.9 bits (228), Expect = 1e-18
Identities = 57/178 (32%), Positives = 87/178 (48%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
+N+ F+GLG MG MAAN++K+G + Y+ + + A G A+
Sbjct: 3 QNIGFIGLGIMGEAMAANILKQGHPLIVYNRTVEKAAALVDAGAMVADKPSLVADASDVI 62
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 540
+LT + V V G++G+++ +G +I+ ST+ K+ + G+ DAPV
Sbjct: 63 ILMLTGEEAVDAVLFGEEGLLSGDCEGKTVINMSTVPVECSKRWAKELADHGMTLIDAPV 122
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMG 714
SG + A TL +AGG + PLL MG K +CG GSG KL N L+G
Sbjct: 123 SGSKVPAQTGTLVILAGGPEAAVRAQEPLLLSMGKKVIYCGPTGSGSAMKLAINLLLG 180
>UniRef50_Q84VC8 Cluster: Gamma hydroxybutyrate dehydrogenase-like
protein; n=3; Magnoliophyta|Rep: Gamma hydroxybutyrate
dehydrogenase-like protein - Oryza sativa subsp.
japonica (Rice)
Length = 293
Score = 95.5 bits (227), Expect = 2e-18
Identities = 57/176 (32%), Positives = 82/176 (46%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
V FLGLG MG MAANL++ GF V ++ + G + +
Sbjct: 3 VGFLGLGIMGKAMAANLLRHGFRVTVWNRTLSKCQELVALGAAVGETPAAVVAKCRYTIA 62
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+L+ L V KDGV+ +G +D ST+D +I +KG F +APVSG
Sbjct: 63 MLSDPSAALSVVFDKDGVLEQIGEGKGYVDMSTVDAATSCKISEAIKQKGGAFVEAPVSG 122
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMG 714
A + L +A G K ++ +P V+G K F G+IG+G KL N +MG
Sbjct: 123 SKKPAEDGQLVILAAGDKVLYDDMVPAFDVLGKKSFFLGEIGNGAKMKLVVNMIMG 178
>UniRef50_A3WAC4 Cluster: Dehydrogenase; n=4; Bacteria|Rep:
Dehydrogenase - Erythrobacter sp. NAP1
Length = 301
Score = 93.9 bits (223), Expect = 5e-18
Identities = 59/179 (32%), Positives = 89/179 (49%), Gaps = 6/179 (3%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYD----PSKDALNAAAKNG-VTPANS-IXXXX 342
K +AFLGLG MGG M +LV+ G GY+ +++ + G V P S
Sbjct: 5 KRIAFLGLGVMGGPMWGHLVRAGHEATGYNRNFAKAEEWSDRLGDEGLVAPIESDAATAV 64
Query: 343 XXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLG 522
+ L ++ V V G++GV+A K+G+ ID +++ P + ++I GL
Sbjct: 65 RGKDVVLACLGNDDDVASVLFGENGVLAAMKRGATFIDHTSVSPGLARRIADECERLGLH 124
Query: 523 FTDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTN 699
DAPVSGG GA N L+ M GG +E + P++ A+ H G+ G+G AK N
Sbjct: 125 AVDAPVSGGQAGAENGKLSIMCGGSEEAMASAQPVMQAYAARIVHIGEAGAGQTAKAIN 183
>UniRef50_Q0LNZ7 Cluster: 3-hydroxyisobutyrate dehydrogenase
precursor; n=1; Herpetosiphon aurantiacus ATCC
23779|Rep: 3-hydroxyisobutyrate dehydrogenase precursor
- Herpetosiphon aurantiacus ATCC 23779
Length = 301
Score = 93.1 bits (221), Expect = 8e-18
Identities = 60/190 (31%), Positives = 83/190 (43%), Gaps = 1/190 (0%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVR-GYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 363
+ +GLG MG MA+NL++ G+ + G ++A A G A S
Sbjct: 6 IGLIGLGAMGAPMASNLLQAGYQLTVGVHQRREAAEQLALQGAIIAESYQALGENSDIVI 65
Query: 364 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 543
+++ V LG +G GS+ ID STI P + I E+ + DAPVS
Sbjct: 66 TMVPDAPQVEAALLGTNGAAYGMAAGSICIDMSTIAPTASRAIAAKLAERQIAMLDAPVS 125
Query: 544 GGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPR 723
GG A LA M GG FER +L V+G + G GSG V KL NN +
Sbjct: 126 GGPARAKTGELAIMVGGEPSTFERCQAVLEVLGGAVSYIGASGSGSVVKLCNNLAISIIA 185
Query: 724 LAXADCXXHG 753
+A + G
Sbjct: 186 MANIEALAFG 195
>UniRef50_Q18X68 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Desulfitobacterium hafniense|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Desulfitobacterium hafniense (strain DCB-2)
Length = 298
Score = 92.7 bits (220), Expect = 1e-17
Identities = 62/184 (33%), Positives = 87/184 (47%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ F+GLG MG MA NL+K G + YD + + G A I S
Sbjct: 3 LGFIGLGQMGKHMALNLLKSGEELIVYDQRPASYPEFEQRGARTAAQIRDVAEADIIFCS 62
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
L +++VV V LG+ G+ + G +++D+STI+ + +I G+ F DAPVSG
Sbjct: 63 -LPNSEVVCQVVLGETGLKKVLRAGQIIVDTSTINYSTTLEIGKQLESVGVEFIDAPVSG 121
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPRL 726
A TL M GG++E FE P L K + GQ GSG + KL N L
Sbjct: 122 MESRAKEGTLTTMCGGKQELFENVKPYLQCFADKILYMGQPGSGQLTKLINQLLFDINVA 181
Query: 727 AXAD 738
A A+
Sbjct: 182 ALAE 185
>UniRef50_A5VEA3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Sphingomonas wittichii RW1|Rep:
2-hydroxy-3-oxopropionate reductase - Sphingomonas
wittichii RW1
Length = 264
Score = 92.7 bits (220), Expect = 1e-17
Identities = 55/189 (29%), Positives = 90/189 (47%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ F+GLG G +A NL+ G + G+D + L+ G T A S
Sbjct: 3 IGFIGLGVQGLPLALNLLDGGHELHGFDVRPEPLDELRDRGGTVAASPAELGAACEVVMI 62
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+ S++ V DV G+DGV+A A+ G +++ S++ + + ++G+ DAPVSG
Sbjct: 63 CVVSDQQVRDVLAGEDGVLASARPGLIVVLHSSVSTDTIAEAAKATRDRGVVLVDAPVSG 122
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPRL 726
G GA T++FM GG + +R PL + G G G+ +AKL + + +
Sbjct: 123 GAQGARARTMSFMVGGEEAALDRCQPLFELSGPNILRTGPAGTATLAKLAHQVAIIGNIM 182
Query: 727 AXADCXXHG 753
A A+ G
Sbjct: 183 AMAEAVRLG 191
>UniRef50_A5GPC0 Cluster: Hydroxyacid dehydrogenase/reductase family
protein; n=14; Cyanobacteria|Rep: Hydroxyacid
dehydrogenase/reductase family protein - Synechococcus
sp. (strain WH7803)
Length = 302
Score = 92.7 bits (220), Expect = 1e-17
Identities = 58/195 (29%), Positives = 96/195 (49%), Gaps = 6/195 (3%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+AF+GLG +G +AANL + G++++ + S+ A N + + PA +
Sbjct: 12 LAFVGLGALGLPIAANLHRAGYSLQVHTRSRSAENDPSLHQGDPAAATLCCASPADAVQG 71
Query: 367 -----ILTSNKVVLDVYL-GKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFT 528
+ S+ ++ L G +G +GSL+ID STI P+ +++ +G+ +
Sbjct: 72 CQALVLCVSDDAAVEAVLWGDNGAGPALAEGSLVIDCSTISPSTSQRMARRLAHRGVRYL 131
Query: 529 DAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXL 708
DAPV+GG GA TL + GG D +R++P+L +G H G +GSG K N L
Sbjct: 132 DAPVTGGTEGAKAGTLTVLCGGSDADLDRAMPVLETIGGSIHHFGAVGSGQQVKAVNQVL 191
Query: 709 MGXPRLAXADCXXHG 753
+ A A+ G
Sbjct: 192 VAGSYAAVAEAIALG 206
>UniRef50_A0G5G5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia phymatum
STM815
Length = 306
Score = 92.7 bits (220), Expect = 1e-17
Identities = 59/191 (30%), Positives = 86/191 (45%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
+ + F+GLGNMGG M LV G +V GYD + + + AA G A+SI
Sbjct: 4 ERIGFIGLGNMGGRMTRRLVDAGISVLGYDTAPERVKAA---GAQAASSIADVMKFADVV 60
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 540
L +KVV V G GV+AH + +++D ST + ++ + G+ + DA +
Sbjct: 61 MMSLPDSKVVEAVVEGDGGVLAHCRARQIVVDLSTAAASSTIRLARRFTQSGVQYVDAGI 120
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXP 720
SGG A L M GG + + +K H G+ G+G KL NN L
Sbjct: 121 SGGAAAAEKGALTLMVGGDASAVDALKWAFAPISSKVAHMGESGAGHTTKLLNNFLNAVS 180
Query: 721 RLAXADCXXHG 753
A A+ G
Sbjct: 181 LSASAEVMVAG 191
>UniRef50_Q47AR2 Cluster: NADP oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Dechloromonas aromatica RCB|Rep: NADP
oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding - Dechloromonas aromatica (strain RCB)
Length = 287
Score = 92.3 bits (219), Expect = 1e-17
Identities = 64/188 (34%), Positives = 90/188 (47%), Gaps = 4/188 (2%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTV----RGYDPSKDALNAAAKNGVTPANSIXXXXXXXX 354
+ F+GLG MG MA NL+K G V R + + L+A AK +PA +
Sbjct: 3 IGFIGLGIMGRPMALNLIKGGHQVTVWARRAESMQPLLDAGAKGAASPAEAARGNELVI- 61
Query: 355 XXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 534
S++ V +V G V + + G + +D STI P ++I G+ F DA
Sbjct: 62 ---SMVADAPDVAEVMRG---VASAGESGLVAVDMSTIAPAAARRIGEDLAAAGIDFIDA 115
Query: 535 PVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMG 714
PVSGG +GA +L+ MAGG F ++ P MG H G G+G VAK N + G
Sbjct: 116 PVSGGEVGAIAGSLSIMAGGSDAAFAKAKPAFECMGKNIVHVGASGAGQVAKAANQIVTG 175
Query: 715 XPRLAXAD 738
LA A+
Sbjct: 176 MGVLAVAE 183
>UniRef50_A3K497 Cluster: Probable 6-phosphogluconate dehydrogenase
protein; n=1; Sagittula stellata E-37|Rep: Probable
6-phosphogluconate dehydrogenase protein - Sagittula
stellata E-37
Length = 298
Score = 92.3 bits (219), Expect = 1e-17
Identities = 59/195 (30%), Positives = 94/195 (48%), Gaps = 3/195 (1%)
Frame = +1
Query: 178 DKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXX 357
DK + F+GLGNMG MA +LV+ GF V YD + A A+ +
Sbjct: 3 DKLIGFIGLGNMGTAMARHLVRGGFEVLAYDIDAEKRAAFAEETGMRNPATVAELAEATV 62
Query: 358 XXSILTSNKVVLDVYL--GKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTD 531
++L + +V V G+ G++ + G+L+ID+++ P +++ + +G D
Sbjct: 63 LLTMLPNGAIVRKVLDEGGEAGLLGQMQPGTLMIDTTSSPPEATRELAAVLNARGCHLVD 122
Query: 532 APVSGGVMGAXNATLAFMAGGRKED-FERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXL 708
APVSG GA A L FM G + ER+ +L +G + FH G +G+G K NN +
Sbjct: 123 APVSGARAGAEAADLVFMIGCDDDAVLERTRAVLSCLGNRLFHLGPVGAGHAMKALNNYV 182
Query: 709 MGXPRLAXADCXXHG 753
+A A+ G
Sbjct: 183 SAAGYVAAAEAMIIG 197
>UniRef50_Q3DYV4 Cluster: NADP oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Chloroflexus|Rep: NADP oxidoreductase,
coenzyme F420-dependent:6-phosphogluconate
dehydrogenase, NAD-binding - Chloroflexus aurantiacus
J-10-fl
Length = 289
Score = 91.9 bits (218), Expect = 2e-17
Identities = 60/184 (32%), Positives = 92/184 (50%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+A +GLG MG MA L+K GF V G++ S L+ A G+ P +
Sbjct: 3 IALIGLGLMGRPMARTLLKAGFNVTGWNRSP--LDPALTEGI-PLAATLAEAAQAETLIL 59
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+L+ + V ++ D ++ ++G L+ID + DP + +G+G+ DAPVSG
Sbjct: 60 MLSDSTAVAELLSRLDPLL---REGQLIIDMGSSDPRHSQTHATTLANRGIGWVDAPVSG 116
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPRL 726
G GA TLA M GG D ER+ P+L +G + H G G+G K+ N ++G
Sbjct: 117 GPEGAAAGTLAIMVGGTASDVERAEPILRALG-RPTHVGPPGAGHTVKVINQLIVGLTIQ 175
Query: 727 AXAD 738
A A+
Sbjct: 176 AVAE 179
>UniRef50_Q84H84 Cluster: Putative oxidoreductase; n=1; Arthrobacter
sp. BP2|Rep: Putative oxidoreductase - Arthrobacter sp.
BP2
Length = 278
Score = 91.5 bits (217), Expect = 2e-17
Identities = 61/189 (32%), Positives = 94/189 (49%), Gaps = 3/189 (1%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSI-XXXXXXXXX 357
K + F+GLG MG MA NL + GF V GYD + + A G+T A ++
Sbjct: 3 KKIGFVGLGTMGLPMAVNLNRAGFEVIGYDAFEGSRQKAIAAGITMAETLKDVAEQADDA 62
Query: 358 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG-LGFTDA 534
S++ +DV LG+DG+++ K +I ST+DP+ ++ E G + A
Sbjct: 63 IVSMVRDYAQNVDVILGQDGLLSANPKNLTIIVMSTLDPDTMNELGQQVEEHGEVRLIAA 122
Query: 535 PVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCG-QIGSGXVAKLTNNXLM 711
VSGG GA TL+ MA G ++ + P +G+ F+ G + G+ AKL NN ++
Sbjct: 123 AVSGGSTGAEAGTLSIMASGAEDVVTAASPYFDAVGSNTFYYGSKPGNSQAAKLVNNLVL 182
Query: 712 GXPRLAXAD 738
G A A+
Sbjct: 183 GINMNAVAE 191
>UniRef50_Q01QM2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Solibacter usitatus Ellin6076|Rep: 3-hydroxyisobutyrate
dehydrogenase - Solibacter usitatus (strain Ellin6076)
Length = 298
Score = 91.5 bits (217), Expect = 2e-17
Identities = 59/178 (33%), Positives = 85/178 (47%), Gaps = 2/178 (1%)
Frame = +1
Query: 184 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAA--KNGVTPANSIXXXXXXXXX 357
N+ FLGLG MG MA NL++ G V + + D A + GV A
Sbjct: 3 NLGFLGLGLMGYPMARNLLRAGHNVAVWSHTSDKARKLADEEKGVFCATPRDVGAGADVV 62
Query: 358 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 537
+ + +V LG G++ + G++++D STI ++I K + F DAP
Sbjct: 63 FLCV-GDTAMAREVILGGQGLIQGLRAGAVVVDCSTIAVADSREIGAALKAKSVDFLDAP 121
Query: 538 VSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLM 711
V+G GA + L FM GG + F + PLL MG K + CG G G AKLT N ++
Sbjct: 122 VTGSTPGAESGNLTFMIGGDEAVFSKIRPLLDPMGKKIYFCGGAGMGLQAKLTQNLVL 179
>UniRef50_A0FZ96 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia phymatum STM815|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Burkholderia phymatum STM815
Length = 305
Score = 91.1 bits (216), Expect = 3e-17
Identities = 56/190 (29%), Positives = 92/190 (48%), Gaps = 1/190 (0%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ ++GLG MGG +A +L+ K + + +D ++ A+ A + G T A +
Sbjct: 3 IGYIGLGAMGGALARHLIGK-YPLSVFDLNRKAVEAFVELGATAAATPAELARNSDVVLL 61
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
L + V V G DG V G ++ID ++ P + + G+ DAPVSG
Sbjct: 62 CLPRSSDVHSVLFGPDGAVEGLSDGKIVIDQTSGVPAETRDFARQLADIGVALFDAPVSG 121
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQ-IGSGXVAKLTNNXLMGXPR 723
+ A T++ +A G K+ FE++LP+L + FHCG+ +G+G K NN + R
Sbjct: 122 AMATAIAGTISIIASGPKDAFEKTLPVLQSISPNVFHCGERVGNGQTMKTVNNMMNVSCR 181
Query: 724 LAXADCXXHG 753
LA + G
Sbjct: 182 LATLEVVAMG 191
>UniRef50_Q8UBW3 Cluster: Oxidoredutase; n=1; Agrobacterium
tumefaciens str. C58|Rep: Oxidoredutase - Agrobacterium
tumefaciens (strain C58 / ATCC 33970)
Length = 300
Score = 90.6 bits (215), Expect = 4e-17
Identities = 60/177 (33%), Positives = 91/177 (51%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
++VAF+G G MGG MA L+ GF+V+ ++ S D A +G A S
Sbjct: 10 RSVAFIGTGLMGGPMARRLLGTGFSVKVWNRSVDKAQALVADGAVLAASPAEAARGADIV 69
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 540
++L+ V +V L + GV KG+++IDSS+I P + ++ G+ DAPV
Sbjct: 70 ITMLSDGNAVGEV-LFEAGVAEALAKGAVVIDSSSIAPPIAREHSSRLQAMGIHHVDAPV 128
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLM 711
SGGV GA TLA MAGG + + + MG + + G G+G + KL N ++
Sbjct: 129 SGGVPGATAGTLAIMAGGDEALISGLVDVFAPMG-RLTYVGPSGAGQLCKLANQQIV 184
>UniRef50_A5VBF0 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=1; Sphingomonas wittichii RW1|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Sphingomonas wittichii RW1
Length = 298
Score = 90.6 bits (215), Expect = 4e-17
Identities = 62/192 (32%), Positives = 86/192 (44%), Gaps = 1/192 (0%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
+ +AFLG+G MG MAA L+ G + ++ S D L G
Sbjct: 3 QRMAFLGIGLMGRPMAARLLDSGHELALWNRSADKLAPLVAAGGRACAIPAEAVEGAAVV 62
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG-LGFTDAP 537
LT V V G+ G G+L++D STI P+ + E G + D P
Sbjct: 63 CLCLTDADAVEQVMFGEGGAARALAPGALVVDFSTIGPDATRGFAKRLAETGDAQWLDCP 122
Query: 538 VSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGX 717
VSGGV GA TLA +AGG +R PLL ++ A+ G +G+G AKL N ++
Sbjct: 123 VSGGVAGAEAGTLAILAGGDAAAIDRVRPLLALLSARVTRMGGVGAGQAAKLCNQLIVAT 182
Query: 718 PRLAXADCXXHG 753
LA A+ G
Sbjct: 183 NMLAIAEAMHVG 194
>UniRef50_A0JXR2 Cluster: 2-hydroxy-3-oxopropionate reductase; n=2;
Arthrobacter|Rep: 2-hydroxy-3-oxopropionate reductase -
Arthrobacter sp. (strain FB24)
Length = 333
Score = 90.6 bits (215), Expect = 4e-17
Identities = 64/191 (33%), Positives = 91/191 (47%), Gaps = 5/191 (2%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
K F+GLG MGG MAANL+K G+ V G++ S AL+ A G A +
Sbjct: 16 KRAGFVGLGLMGGPMAANLLKAGWNVTGWNRSAAALDDLAARGGMRAADVASLRDEPVII 75
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKG--SLLIDSSTIDPNVPKQ--IFPIALEKGLGFT 528
+L + D G A G ++++ S++ P + + A +G
Sbjct: 76 F-MLPDLSYIEDAAAGLLAGWADEPPGPGTVVVVMSSVSPAAVRDFGVKVSAASRGNAVV 134
Query: 529 -DAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNX 705
DAPVSGG GA + TLA M G ++DF+R LPL MG G +GSG +AK N
Sbjct: 135 VDAPVSGGTKGAEDGTLAIMVGAGEQDFQRLLPLFNAMGGTVRRLGPLGSGSLAKACNQL 194
Query: 706 LMGXPRLAXAD 738
++G A A+
Sbjct: 195 IVGTTTAALAE 205
>UniRef50_A3X9R7 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=2; Rhodobacterales|Rep: 3-hydroxyisobutyrate
dehydrogenase family protein - Roseobacter sp. MED193
Length = 300
Score = 90.2 bits (214), Expect = 6e-17
Identities = 53/174 (30%), Positives = 84/174 (48%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ +GLG MGG + L+ + + +D +A AA G A+S+ S
Sbjct: 17 IGLVGLGAMGGGYLSRLMAQNCDLMCFDAMPEARARAAAAGAKVADSLADFSACDTVILS 76
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+ ++ + + G + KKGS+++D+ST +P+ K++ A G F D PVSG
Sbjct: 77 L--PKAAIVSAVMEELG--PYLKKGSIVVDTSTSEPDTTKRLAAAAESNGYTFLDGPVSG 132
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXL 708
G +GA T+ + GG + F + PLL M K H G G+G K+ NN L
Sbjct: 133 GPLGARTGTMTMVVGGDEAGFTKVRPLLEKMTGKLVHIGPSGAGHTVKIANNLL 186
>UniRef50_A6EH53 Cluster: Putative uncharacterized protein; n=1;
Pedobacter sp. BAL39|Rep: Putative uncharacterized
protein - Pedobacter sp. BAL39
Length = 292
Score = 89.4 bits (212), Expect = 1e-16
Identities = 49/173 (28%), Positives = 83/173 (47%)
Frame = +1
Query: 193 FLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSIL 372
++GLGNMG MA ++ KG+++ Y+ + G A + ++
Sbjct: 17 WIGLGNMGVPMAGQVLNKGYSLTVYNRTLSKTEPLVAQGAKVAGTPGELIAATDIVFLMV 76
Query: 373 TSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGV 552
+ + V ++ G DG+++ G ++++ ST+ P + ++ G+ + DAPVSG V
Sbjct: 77 SDDHAVASLFEGADGLLSKELHGKVIVNMSTVSPAISIKMAAACSAVGIEYLDAPVSGSV 136
Query: 553 MGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLM 711
A + L M GG ++ F + PLL MG H G G G AKL N L+
Sbjct: 137 KQATDGQLVIMVGGEEQAFHAAEPLLSCMGKLVMHLGASGIGNKAKLAINTLL 189
>UniRef50_Q1IQE6 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=1; Acidobacteria bacterium Ellin345|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Acidobacteria bacterium (strain Ellin345)
Length = 282
Score = 89.0 bits (211), Expect = 1e-16
Identities = 60/173 (34%), Positives = 84/173 (48%), Gaps = 1/173 (0%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPS-KDALNAAAKNGVTPANSIXXXXXXXXXXX 363
VAFLGLG MG MAANL K G V ++ + KD A TPA +
Sbjct: 3 VAFLGLGIMGRPMAANLAKAGNEVTVWNRTPKDVEGAHVAK--TPAEAAKHADVVWMC-- 58
Query: 364 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 543
++ V V G GV + G +++DSSTI P + KG + DAP++
Sbjct: 59 --VSDTNAVERVLFGDGGVEPVLRAGMVVVDSSTISPVETLKFAERVRAKGADYIDAPIT 116
Query: 544 GGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNN 702
G +GA +A L FM G + E ++ PL MG K H G++G G +K++ N
Sbjct: 117 GSKIGAESAQLIFMVGAKDETLKKLEPLFLQMGKKIVHMGEVGKGQASKISLN 169
>UniRef50_A1ZWM5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Microscilla marina ATCC 23134|Rep: 3-hydroxyisobutyrate
dehydrogenase - Microscilla marina ATCC 23134
Length = 295
Score = 89.0 bits (211), Expect = 1e-16
Identities = 60/189 (31%), Positives = 86/189 (45%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+AF+GLG MG MA+NL+K + Y+ S A G A++ S
Sbjct: 3 IAFIGLGIMGSRMASNLLKHKVDLTVYNRSLAATTPLVALGAKVAHTTTEAVKEADIVFS 62
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+L S +VV V G+ G ++ K +L ID STI P A + + F +APV+G
Sbjct: 63 MLASPQVVKAVAYGQTGFLSKMKSKALWIDCSTISPAFALASAQEASKHEVVFVEAPVAG 122
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPRL 726
A NA L F+ GG ++ P + +MG K H G I K+ N L+ L
Sbjct: 123 TKSHAENAELVFLVGGGTTAIAQATPYMEMMGKKVVHIGAISKASALKILINYLLAQGML 182
Query: 727 AXADCXXHG 753
A A+ G
Sbjct: 183 AFAEALVVG 191
>UniRef50_A1R2J4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Arthrobacter aurescens TC1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Arthrobacter aurescens (strain TC1)
Length = 332
Score = 89.0 bits (211), Expect = 1e-16
Identities = 60/191 (31%), Positives = 82/191 (42%), Gaps = 2/191 (1%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ F+GLGNMG M NL GF + D K++ NG A +
Sbjct: 26 IGFIGLGNMGSGMTRNLQAAGFHLVVNDVRKESAAELLANGAEWAEDAAAVAAGSDVVIT 85
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+L + K V V +G G++A G +D ST P V ++ +G+ DAPVSG
Sbjct: 86 MLPTPKHVETVAMGPGGILAGMPDGGTWVDMSTSVPEVANRVREAGSVRGIRVLDAPVSG 145
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQ--FHCGQIGSGXVAKLTNNXLMGXP 720
+GA N L GG D ER P+ MG + H G G+G KL N L
Sbjct: 146 MSVGAANGMLQIFVGGEPADVERLRPVFEAMGDPERILHVGGHGAGYAVKLMINQLWFSH 205
Query: 721 RLAXADCXXHG 753
+A A+ G
Sbjct: 206 LVATAEVLSTG 216
>UniRef50_Q606G9 Cluster: Oxidoreductase, Gfo/Idh/MocA family; n=6;
Proteobacteria|Rep: Oxidoreductase, Gfo/Idh/MocA family
- Methylococcus capsulatus
Length = 289
Score = 88.6 bits (210), Expect = 2e-16
Identities = 56/188 (29%), Positives = 89/188 (47%), Gaps = 1/188 (0%)
Frame = +1
Query: 193 FLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPA-NSIXXXXXXXXXXXSI 369
F+GLG MG MA NL + G ++ + + A A TPA ++ +
Sbjct: 5 FVGLGAMGLGMARNLRRAGLLAGVWNRTPEKARAFAAETGTPAWATLTEMAPACDVIVTC 64
Query: 370 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 549
++++ VL+V + + G++++D ST+ ++ + + G F DAPVSGG
Sbjct: 65 VSADADVLEVIAA---LTPGLRPGAVIVDCSTVGVATARRAAEVVRQAGGDFLDAPVSGG 121
Query: 550 VMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPRLA 729
V GA + TLA M GGR E E+ P+L MG++ H G G+G K N + A
Sbjct: 122 VEGARDGTLALMIGGRAETVEKVRPVLAAMGSRLMHMGDTGAGQATKAVNQVMCAGINQA 181
Query: 730 XADCXXHG 753
+ G
Sbjct: 182 VTEALAFG 189
>UniRef50_Q0RCX7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Frankia alni ACN14a|Rep: 3-hydroxyisobutyrate
dehydrogenase - Frankia alni (strain ACN14a)
Length = 313
Score = 88.6 bits (210), Expect = 2e-16
Identities = 57/177 (32%), Positives = 83/177 (46%), Gaps = 2/177 (1%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKD--ALNAAAKNGVTPANSIXXXXXXXXXX 360
V F+GLG MG MA +L + GF Y+ ++ A +A + G A
Sbjct: 3 VGFVGLGTMGFPMAGHLARAGFDTVVYNRTETTAARWSAVQRGRVAATPAQAAAGSDVVC 62
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 540
+ + V V LG DG + G+ ++D +T + +I A E G+GF DAPV
Sbjct: 63 VCVGADDDV-RSVLLGPDGALGALAPGATIVDHTTTSAELAVEIAARAAEVGVGFVDAPV 121
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLM 711
SGG GA L+ M GG + ER P+L GA G +G+G + K+ N L+
Sbjct: 122 SGGQAGAEAGRLSVMCGGEVDTVERVRPVLAAYGATITRIGPVGTGQLTKMVNQILV 178
>UniRef50_A7IE35 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Xanthobacter sp. (strain Py2)
Length = 330
Score = 88.6 bits (210), Expect = 2e-16
Identities = 53/176 (30%), Positives = 80/176 (45%), Gaps = 1/176 (0%)
Frame = +1
Query: 190 AFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSI 369
A +GLG+MG MA +L + GF V G+D + A+ A G A+S S+
Sbjct: 36 AVIGLGSMGYGMAQSLKRAGFDVAGFDVNAAAVERFAAEGGRGASSPAEAARDADVVVSV 95
Query: 370 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 549
+ + + G DGV G++ + S+T+DP + + + G + DAP+SGG
Sbjct: 96 VVNAAQTETILFGADGVAQTLADGAVFLSSATMDPEIARTLAARLEATGRLYLDAPISGG 155
Query: 550 VMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQI-GSGXVAKLTNNXLMG 714
A L +A G F ++ P L M AK + G G G K+ N L G
Sbjct: 156 AQRAAEGALTILASGSPAAFAKARPALDAMAAKLYELGDAPGQGAAFKMINQLLAG 211
>UniRef50_A5P0V0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=3; Rhizobiales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Methylobacterium sp. 4-46
Length = 299
Score = 88.6 bits (210), Expect = 2e-16
Identities = 64/189 (33%), Positives = 87/189 (46%), Gaps = 5/189 (2%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
VAF+GLG MG MA NLV KGF VRGYD ++ A A+ G A+++
Sbjct: 6 VAFVGLGAMGLPMAQNLVAKGFPVRGYDVRPESRAALARAGGEAADTLRAAAAGAGALVL 65
Query: 367 ILTSNKVVLDVYLG----KDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 534
++ + V G +G + + +I +T P + + G F DA
Sbjct: 66 MVVNAAQAEAVLFGGGAPAEGALEVLAPDAAVILMATCPPQAVEGLAARVAAAGRRFVDA 125
Query: 535 PVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCG-QIGSGXVAKLTNNXLM 711
PVSGGV+GA +L MA E F PLL +GA+ FH G + G G K N L
Sbjct: 126 PVSGGVVGAEAGSLTVMAAAPAEVFGAVRPLLDAVGARIFHVGTRPGQGATVKAVNQLLC 185
Query: 712 GXPRLAXAD 738
G A A+
Sbjct: 186 GVHIAAAAE 194
>UniRef50_Q39FA8 Cluster: 2-hydroxy-3-oxopropionate reductase; n=22;
Burkholderiales|Rep: 2-hydroxy-3-oxopropionate reductase
- Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 287
Score = 88.2 bits (209), Expect = 2e-16
Identities = 56/179 (31%), Positives = 84/179 (46%), Gaps = 3/179 (1%)
Frame = +1
Query: 211 MGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSILTSNKVV 390
MG M +L+ G V ++ S+D A K+G + + + V
Sbjct: 1 MGAPMIRHLLAAGHRVSVWNRSRDKAEALVKDGAQVVGTPRELAERVDTVFVCVLDGRAV 60
Query: 391 LDVYLGKDGVV---AHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGA 561
DV G+ G++ A A++ ++D S+I P + A G+G+ DAPVSGGV GA
Sbjct: 61 GDVVFGEHGLLSGDAAARRLQRIVDHSSIPPAATRDYAARATALGVGWVDAPVSGGVPGA 120
Query: 562 XNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPRLAXAD 738
TLA MAGGR D + PL+ ++ H G G+G AKL N ++ A A+
Sbjct: 121 QAGTLAVMAGGRAADLDAVRPLIDTYASRITHMGDAGAGQTAKLCNQAIVTATVTAIAE 179
>UniRef50_A7PEG7 Cluster: Chromosome chr11 scaffold_13, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr11 scaffold_13, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 348
Score = 87.8 bits (208), Expect = 3e-16
Identities = 64/195 (32%), Positives = 91/195 (46%), Gaps = 1/195 (0%)
Frame = +1
Query: 145 TAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPAN 324
TAA S ++ V ++G G MG M A+L+K G+TV ++ + G A+
Sbjct: 37 TAAVAEPVSPSNTRVGWIGTGVMGRSMCAHLMKAGYTVTIFNRTISKAQPLLDMGAHHAS 96
Query: 325 SIXXXXXXXXXXXSILTSNKVVLDVYLG-KDGVVAHAKKGSLLIDSSTIDPNVPKQIFPI 501
S SI+ V V L G ++ + G +L+D +T DP++ +I
Sbjct: 97 SPLALASQSDVVFSIVGFPSDVRSVLLDPSSGALSGLRPGGVLVDMTTSDPSLAAEIASS 156
Query: 502 ALEKGLGFTDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGX 681
A +G DAPVSGG GA NATLA AGG + R PL +G K + G G G
Sbjct: 157 AASRGCFSVDAPVSGGDRGAKNATLAIFAGGDESVVRRLNPLFSHLG-KVNYMGGPGKGQ 215
Query: 682 VAKLTNNXLMGXPRL 726
AKL N ++ L
Sbjct: 216 YAKLANQIIIASTML 230
>UniRef50_Q8TT25 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Methanosarcina|Rep: 3-hydroxyisobutyrate dehydrogenase -
Methanosarcina acetivorans
Length = 300
Score = 87.8 bits (208), Expect = 3e-16
Identities = 59/185 (31%), Positives = 85/185 (45%), Gaps = 2/185 (1%)
Frame = +1
Query: 166 SSNTDKN--VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXX 339
+S DKN V +GLG MG A+NL+ +G+ V Y+ +K+ + G T ++
Sbjct: 3 TSGCDKNITVGVIGLGIMGSSFASNLLSRGYNVHVYNRTKEKAQPLIERGATFHSTPREL 62
Query: 340 XXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGL 519
+ LT V V G+DG++ AKKG L ID STIDP+ + A + GL
Sbjct: 63 ASVADIIMTSLTDEAAVNSVAFGEDGLLNGAKKGCLWIDLSTIDPSSSVKHAEAAKKAGL 122
Query: 520 GFTDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTN 699
D PV G A L + GG +E + L +G + G G+G KL
Sbjct: 123 ERLDTPVVGSKDLASKGELIILVGGSQEVLRKHEKFLNKLGKSVIYLGADGNGHKMKLAI 182
Query: 700 NXLMG 714
N +G
Sbjct: 183 NLHLG 187
>UniRef50_A3H5R1 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Caldivirga maquilingensis IC-167|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Caldivirga maquilingensis IC-167
Length = 295
Score = 87.8 bits (208), Expect = 3e-16
Identities = 57/186 (30%), Positives = 89/186 (47%), Gaps = 1/186 (0%)
Frame = +1
Query: 184 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKD-ALNAAAKNGVTPANSIXXXXXXXXXX 360
NV +GLG MG +A NL G + ++ + A+ A +N V N+
Sbjct: 3 NVGLIGLGTMGWRIAKNLKDDGLLIGVFNRTMSKAIKFAEENKVNVFNNPAELARNVDVV 62
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 540
SI++ + V + LG++GV+ K+GSL+I+ STI P+ ++ EKG DAP+
Sbjct: 63 LSIVSDDDAVKSIMLGENGVINGIKQGSLVIEMSTISPSTSIELANKIKEKGGLMVDAPI 122
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXP 720
G + + GG +E +ER+ ++ H G G G AKL NN L+G
Sbjct: 123 IGTSILIEKREAVVLIGGEREAYERAYEVVKHFARYVVHVGPNGYGLYAKLINNALLGSY 182
Query: 721 RLAXAD 738
A A+
Sbjct: 183 VAALAE 188
>UniRef50_Q89M84 Cluster: Blr4309 protein; n=6;
Bradyrhizobiaceae|Rep: Blr4309 protein - Bradyrhizobium
japonicum
Length = 293
Score = 87.0 bits (206), Expect = 5e-16
Identities = 58/181 (32%), Positives = 86/181 (47%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
VAF+GLG MG MA + GFTV ++ SK G A S +
Sbjct: 4 VAFIGLGRMGHGMAGRYLDAGFTVTLWNRSKTKAEDLIARGAHWATSPEDAAIDADAVVT 63
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
++ ++ V+LG G AK G++ I+ ST+ + +++ +GL + D PV+G
Sbjct: 64 MVADDEASRAVWLGPKGAAKTAKAGTIAIECSTVSYDHAREMGRELNARGLIYIDCPVTG 123
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPRL 726
A L + G D ER+ P L +G+ H G +GSG V KL NN LMG ++
Sbjct: 124 LPDAAAAGKLTLLVGADAADLERARPYLEPIGSTIRHFGAVGSGTVYKLINN-LMGAIQI 182
Query: 727 A 729
A
Sbjct: 183 A 183
>UniRef50_Q39MY1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Burkholderia sp. 383|Rep: 3-hydroxyisobutyrate
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 303
Score = 87.0 bits (206), Expect = 5e-16
Identities = 59/186 (31%), Positives = 86/186 (46%), Gaps = 1/186 (0%)
Frame = +1
Query: 184 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 363
++ FLGLG MG MA L+ + + YDPS A+ G S
Sbjct: 6 DIGFLGLGKMGAPMAERLLGQACRLHVYDPSAQAVAPFVDGGAVAHASPRAVADAASIVF 65
Query: 364 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 543
+ L + V L V LG DGVV H L ++ STI ++ ++I ++G+ DAPVS
Sbjct: 66 ACLPNRDVSLAVGLGPDGVV-HGSAVRLYVEMSTIGQDMIERIGEGLAQRGIDIVDAPVS 124
Query: 544 GGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCG-QIGSGXVAKLTNNXLMGXP 720
GG A TLA + G E+ PLL +G + F G + G + K+ NN +M
Sbjct: 125 GGPSAARAGTLAMLVSGMPSAVEQVSPLLERIGKEVFPMGDRPGMAQIMKIVNNVVMAAN 184
Query: 721 RLAXAD 738
+ A+
Sbjct: 185 LVVCAE 190
>UniRef50_A0QUD5 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=1; Mycobacterium smegmatis str. MC2 155|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 326
Score = 86.2 bits (204), Expect = 9e-16
Identities = 55/177 (31%), Positives = 86/177 (48%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
+ V FLGLGNMG MA LV G + Y+ + A G A S+
Sbjct: 11 QRVGFLGLGNMGRPMARRLVASGTPLTVYNRTAAKCAEFADLGCEVAESVARMGHCSVLL 70
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 540
+ T + V VYLG DG+VA+A+ G++L+D STI P++ ++ G+ F APV
Sbjct: 71 TMLGTDDDVA-QVYLGDDGLVANARAGAVLVDCSTISPDMSARVRARCDRAGVHFLAAPV 129
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLM 711
+GG + LA G ++ FE + +L V+ + G + + K+ +N L+
Sbjct: 130 AGGPPVIESGGLAMAVSGDRQAFEHAADVLRVVAPNLIYVGPGDTSRLVKICHNLLV 186
>UniRef50_Q656T5 Cluster: Oxidoreductase-like; n=3; Oryza
sativa|Rep: Oxidoreductase-like - Oryza sativa subsp.
japonica (Rice)
Length = 341
Score = 86.2 bits (204), Expect = 9e-16
Identities = 63/222 (28%), Positives = 91/222 (40%)
Frame = +1
Query: 49 LLCARAHGRTLN*EKNKFKMAARTILSTQCLYTAARRAYSSNTDKNVAFLGLGNMGGFMA 228
LLCARA AR + S C +++ + V FLGLG MG MA
Sbjct: 9 LLCARAAAAAPTLRLRGGGRGARLVFS--CSASSSSPSGEGGFSGKVGFLGLGIMGAPMA 66
Query: 229 ANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSILTSNKVVLDVYLG 408
+NL+ G V ++ ++ + G S ++L + ++V G
Sbjct: 67 SNLINAGCDVTVWNRTRSKCDPLLSLGAKYEPSPADVASSCDVTFAMLADPESAVEVACG 126
Query: 409 KDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAXNATLAFMA 588
+G G +D ST+D K I G F +APVSG A + L F+
Sbjct: 127 ANGAAQGMAPGKGYVDVSTVDAATSKLIGKHITSTGASFLEAPVSGSKKPAEDGLLIFLT 186
Query: 589 GGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMG 714
G + + R LL VMG +F G +G G KL N +MG
Sbjct: 187 AGDESLYNRVASLLDVMGKSRFFLGDVGKGADMKLVVNMVMG 228
>UniRef50_A3JU55 Cluster: Predicted dehydrogenase, with
NAD(P)-binding Rossmann-fold domain; n=2; Bacteria|Rep:
Predicted dehydrogenase, with NAD(P)-binding
Rossmann-fold domain - Rhodobacterales bacterium
HTCC2150
Length = 302
Score = 85.8 bits (203), Expect = 1e-15
Identities = 53/174 (30%), Positives = 80/174 (45%), Gaps = 1/174 (0%)
Frame = +1
Query: 196 LGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSILT 375
+GLG+MG +A NL+K GF G D + + A + G A + ++
Sbjct: 6 IGLGDMGSGLAKNLLKAGFETTGIDMKPERMAAFVEMGGRAAVDVADVGANADAVFVMVM 65
Query: 376 SNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVM 555
+ V V G+ G++AH KG +I S+TI P ++I + G+ D PVSGG
Sbjct: 66 NGDQVKSVLFGEGGLLAHMPKGGAVILSATIKPVEAEEIGAAMADSGIHLIDTPVSGGFP 125
Query: 556 GAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCG-QIGSGXVAKLTNNXLMG 714
GA TL MA G E + P++ + A + G + G G K L+G
Sbjct: 126 GAQGGTLTMMAAGVDEVLDTYAPVMEAVSATIWCVGTEAGQGQTVKACLQSLLG 179
>UniRef50_Q1N6I0 Cluster: Putative oxidoreductase protein; n=1;
Oceanobacter sp. RED65|Rep: Putative oxidoreductase
protein - Oceanobacter sp. RED65
Length = 289
Score = 85.4 bits (202), Expect = 2e-15
Identities = 53/174 (30%), Positives = 85/174 (48%), Gaps = 2/174 (1%)
Frame = +1
Query: 184 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKN--GVTPANSIXXXXXXXXX 357
N++F+GLG MG MA +LV+ + ++ S +N T ANS+
Sbjct: 2 NISFIGLGKMGYPMAKHLVQANHQLEVFNRSPSKSEDFKRNFEQCTIANSLTDCGKHSEI 61
Query: 358 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 537
+ +++ V + GKD + ++ K G+L+ID +T + ++ LEK + + DAP
Sbjct: 62 IILCIGNDEDVRNTLTGKDSLYSNLKPGTLVIDHTTTSAELACEMQAKLLEKQVDYVDAP 121
Query: 538 VSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTN 699
VSGG GA + L M GG+ ER+ + H G IGSG + K+ N
Sbjct: 122 VSGGEQGAISGQLTIMCGGQALAAERAQGITQAYSKSFTHMGPIGSGQLTKMVN 175
>UniRef50_Q1B326 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein precursor; n=7; Bacteria|Rep:
6-phosphogluconate dehydrogenase, NAD-binding protein
precursor - Mycobacterium sp. (strain MCS)
Length = 299
Score = 85.4 bits (202), Expect = 2e-15
Identities = 53/180 (29%), Positives = 89/180 (49%), Gaps = 1/180 (0%)
Frame = +1
Query: 175 TDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXX 354
++ ++ F+GLGNMG MAANL+ G V Y+ S D ++A + G PA ++
Sbjct: 2 SNMHIGFIGLGNMGSAMAANLLAAGHDVTAYNRSPDKVDALSAEGARPARTV-AEACQGD 60
Query: 355 XXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 534
++L ++ V V G DG+VA + ++ + SSTI + +++ E G F A
Sbjct: 61 VVVTMLANDDAVEAVSFGDDGIVASLRPDAIHVSSSTISLALAERLTAAHAEGGSRFVSA 120
Query: 535 PVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCG-QIGSGXVAKLTNNXLM 711
PV G A A L +A G + E P+ +G + F G + + + K++ N L+
Sbjct: 121 PVFGRPEAAAAAKLFVVAAGAPDTVEALAPVFEAIGQRTFVVGTEPKAANLVKVSGNFLI 180
>UniRef50_A3WMG5 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase; n=1; Idiomarina baltica OS145|Rep:
Probable 3-hydroxyisobutyrate dehydrogenase - Idiomarina
baltica OS145
Length = 284
Score = 85.4 bits (202), Expect = 2e-15
Identities = 53/177 (29%), Positives = 89/177 (50%), Gaps = 1/177 (0%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+AFLGLG MG MA +L+ G ++ ++ ++ + G A++ +
Sbjct: 4 IAFLGLGAMGIRMAQHLIDAGHSLTVWNRTESRAEPLLEQGAQWADTPAEAAQGAELVIA 63
Query: 367 ILTSNKVVLDVYLGKD-GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 543
++ + V+L + G ++ I+SST+ + K++ A ++G +APVS
Sbjct: 64 MVRDDDASAAVWLDEQTGAFKGMSDNAIAIESSTLSVDWVKELAQQAQQRGKQLIEAPVS 123
Query: 544 GGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMG 714
G A NA L ++ GG R+ P+L +MG K H G++GSG +AKL N LMG
Sbjct: 124 GSRPQAQNAELVYLVGGDAHLVNRAEPVLSLMGKKVNHTGEMGSGALAKLVTNTLMG 180
>UniRef50_A1UJF2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=6; Actinomycetales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Mycobacterium sp. (strain KMS)
Length = 272
Score = 85.4 bits (202), Expect = 2e-15
Identities = 51/174 (29%), Positives = 78/174 (44%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
V F+GLG+ GG MA +V+ G+ + + +L A A S
Sbjct: 3 VGFIGLGSQGGPMARRIVEGGYELTLWARRPASLEPYADTAAKTAGSPAELAAASDLVCV 62
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+ + V +V G GV+A G+++ ST+ P+ ++I A + + DAPVSG
Sbjct: 63 CVVGDDDVREVLYGDTGVLAGLAPGAMIAIHSTVHPDTCREIAEKAAAQNVSVIDAPVSG 122
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXL 708
G L M GG + D E++ P+ H G +GSG V K+ NN L
Sbjct: 123 GAPAVEQGKLLVMVGGEEADVEKARPVFATYADPIVHLGPLGSGQVTKILNNLL 176
>UniRef50_A0NRG5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein; n=1; Stappia aggregata IAM
12614|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
protein - Stappia aggregata IAM 12614
Length = 291
Score = 85.4 bits (202), Expect = 2e-15
Identities = 55/176 (31%), Positives = 80/176 (45%), Gaps = 1/176 (0%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKD-ALNAAAKNGVTPANSIXXXXXXXXXXX 363
V F GLG MG MAANL G V ++ + + A A+ + PA +
Sbjct: 3 VGFAGLGRMGVRMAANLAAAGLEVSIWNRTAETARTFASAHNAFPAATPKDLAERSDIVI 62
Query: 364 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 543
++L + VY G DG+ + +L++ T+ + +++ A EKG F DAPVS
Sbjct: 63 TMLADDAAAETVYFGPDGLFEASSGAQVLVEMGTLSVPMAERLARAAQEKGRRFVDAPVS 122
Query: 544 GGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLM 711
G A +A L MAG D L V+G K G+ G+G KL N L+
Sbjct: 123 GATQAAKDAKLLIMAGATASDAPELAALFDVLGRKTIWLGKAGAGAAMKLGVNMLI 178
>UniRef50_Q4PCH4 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 366
Score = 85.4 bits (202), Expect = 2e-15
Identities = 74/242 (30%), Positives = 110/242 (45%), Gaps = 33/242 (13%)
Frame = +1
Query: 127 STQC-LYTAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKK--------GFTVRGYDPSK 279
+T+C L+ RR + K + F+GLG MG MA NL+ K T +D +
Sbjct: 4 TTRCMLHHTIRRCVPHDRSKTIGFIGLGAMGKEMANNLLSKTLASNPDPAVTFVVHDAFE 63
Query: 280 DALNA--AAKNGVTP------ANSIXXXXXXXXXXXSILTSNKVVLDVYLGKDGV----- 420
++ A + P A+S ++L S+ V VY ++G+
Sbjct: 64 QSITRFLTANTSLYPNRNILAASSPAGIAKLSGTIVTMLPSSPQVESVYTHENGILDGLE 123
Query: 421 ------VAHAKKGSLLIDSSTIDPNVPKQ----IFPIALEKGLGFTDAPVSGGVMGAXNA 570
V A+ +L ID +T+DP+V Q I DAPVSGGV+GA A
Sbjct: 124 SFQAAAVDDAQAKTLCIDCTTLDPDVAVQTATAIKNANANGAFDMIDAPVSGGVVGANAA 183
Query: 571 TLAFMAGGRKED-FERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPRLAXADCXX 747
TL+FM G F + P L +MG++ HCG+ G+G +AK+ NN L+G L +
Sbjct: 184 TLSFMVGSDSSTTFASAEPYLSLMGSRAVHCGKNGNGLIAKIANNLLLGISMLGVTEAML 243
Query: 748 HG 753
G
Sbjct: 244 LG 245
>UniRef50_Q8EW87 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Mycoplasma penetrans|Rep: 3-hydroxyisobutyrate
dehydrogenase - Mycoplasma penetrans
Length = 288
Score = 84.6 bits (200), Expect = 3e-15
Identities = 54/185 (29%), Positives = 86/185 (46%), Gaps = 1/185 (0%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ ++G G MG M L G + Y+ + + +N + SI +
Sbjct: 3 ITWIGTGIMGKAMLNRLASHGHIIHAYNRTYEKMNDLNHPNILKFRSIKDAVKDTNIIMT 62
Query: 367 ILTSNKVVLDVYLGKD-GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 543
++ VLD+YL + G+ + + ID +T PN Q+ + KG+ DAPV+
Sbjct: 63 MVGYPSDVLDIYLNDEYGIFNYVSSEQICIDFTTSSPNFAVQLANNS--KGIKVLDAPVT 120
Query: 544 GGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPR 723
GG +GA N TL+ M GG E F++ +L ++G K + G G G AKL N L+
Sbjct: 121 GGDIGALNGTLSIMVGGDFETFKKVESILKILGNKINYFGSAGKGQHAKLFNQILVAVNT 180
Query: 724 LAXAD 738
A A+
Sbjct: 181 FATAE 185
>UniRef50_Q7NR40 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase; n=1; Chromobacterium violaceum|Rep:
Probable 3-hydroxyisobutyrate dehydrogenase -
Chromobacterium violaceum
Length = 296
Score = 84.6 bits (200), Expect = 3e-15
Identities = 55/185 (29%), Positives = 86/185 (46%), Gaps = 4/185 (2%)
Frame = +1
Query: 172 NTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDAL----NAAAKNGVTPANSIXXX 339
N K +A +G G MG + L+ G+ VR Y+ S + +A A TPA ++
Sbjct: 5 NAGKRLALIGCGAMGTALGLRLLGLGWEVRVYNRSPERTAPLRDAGASAHATPAEAVAGA 64
Query: 340 XXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGL 519
++LT + + + G +G+ + G L+D T P + A G
Sbjct: 65 DWVA----TVLTDSAALRALLFGDNGIASAPAAGRRLVDLGTHQPTQLAALGAEAAAAGW 120
Query: 520 GFTDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTN 699
+AP++G V A + TL F+ GG + D E + PLL +G H G +G+G AKL
Sbjct: 121 PLVEAPMTGSVHDASHGTLHFLVGGAEADVEWASPLLWALGRGVHHLGGLGAGNTAKLAL 180
Query: 700 NXLMG 714
N L+G
Sbjct: 181 NLLVG 185
>UniRef50_Q49A26 Cluster: Cytokine-like nuclear factor n-pac; n=46;
Euteleostomi|Rep: Cytokine-like nuclear factor n-pac -
Homo sapiens (Human)
Length = 553
Score = 84.2 bits (199), Expect = 4e-15
Identities = 50/196 (25%), Positives = 87/196 (44%)
Frame = +1
Query: 127 STQCLYTAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKN 306
S Q + A + TDK + FLGLG MG + +NL+K G TV ++ + + + +
Sbjct: 250 SIQAADSTAVNGSITPTDKKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQE 309
Query: 307 GVTPANSIXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPK 486
G + + ++ K D+ LG GV+ + G +D ST+D +
Sbjct: 310 GARLGRTPAEVVSTCDITFACVSDPKAAKDLVLGPSGVLQGIRPGKCYVDMSTVDADTVT 369
Query: 487 QIFPIALEKGLGFTDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQ 666
++ + + +G F +APVSG + + L +A G + +E MG F G+
Sbjct: 370 ELAQVIVSRGGRFLEAPVSGNQQLSNDGMLVILAAGDRGLYEDCSSCFQTMGKTSFFLGE 429
Query: 667 IGSGXVAKLTNNXLMG 714
+G+ L N + G
Sbjct: 430 VGNAAKMMLIVNMVQG 445
>UniRef50_A7DSF1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
2-hydroxy-3-oxopropionate reductase - Candidatus
Nitrosopumilus maritimus SCM1
Length = 292
Score = 84.2 bits (199), Expect = 4e-15
Identities = 54/186 (29%), Positives = 82/186 (44%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
K + +GLG +G + +L++ GF V ++ SKD A + G T +S
Sbjct: 2 KKIGIVGLGMLGNAVGLHLLESGFEVTVFNRSKDKTIQAKEKGATVVDSPKEVAEKSDLV 61
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 540
++ V +V ++G++ K ++ D STIDP+ K I LE G+ D PV
Sbjct: 62 IIVVKDADAVKEVSFEREGIIKSENKKLIVADMSTIDPSESKNISDKFLEFGIHKLDIPV 121
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXP 720
GG A L MA G KE FE + + K F G+ G KL N +
Sbjct: 122 MGGPNVAITGDLVMMASGNKESFEECKKVFEKIANKVFFLGEKGVAHSIKLAMNLQITML 181
Query: 721 RLAXAD 738
LA ++
Sbjct: 182 ALALSE 187
>UniRef50_Q13LQ9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=11;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Burkholderia xenovorans (strain LB400)
Length = 296
Score = 83.8 bits (198), Expect = 5e-15
Identities = 61/180 (33%), Positives = 84/180 (46%), Gaps = 6/180 (3%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNA---AAKNGVTPANSIXXXXXXX 351
K V F+GLG MG M L K GF + + DA A A ++G N+
Sbjct: 5 KRVGFIGLGMMGAPMVQCLRKAGFEL--FIDDADAARADTLAEQSGSHRLNA--DNAGSL 60
Query: 352 XXXXSILTSNKVVLDVYLG---KDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLG 522
++L ++ +V V LG G A KG+++ID S+ +P + + + L
Sbjct: 61 DALITMLPNSAIVEAVVLGDGNNTGWAARLAKGAVVIDMSSSEPERSRALGKTLEAQRLA 120
Query: 523 FTDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNN 702
+ DAPVSGGV A TLA + GG + R PLL MG H G G+G AK NN
Sbjct: 121 YLDAPVSGGVKRAKEGTLAILVGGHADVLARCKPLLDAMGTNVLHIGTAGAGHAAKALNN 180
>UniRef50_Q3W9L4 Cluster: Putative uncharacterized protein; n=1;
Frankia sp. EAN1pec|Rep: Putative uncharacterized
protein - Frankia sp. EAN1pec
Length = 294
Score = 83.4 bits (197), Expect = 6e-15
Identities = 55/173 (31%), Positives = 81/173 (46%), Gaps = 1/173 (0%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
V F+GLG+ GG MA + +G+ + + ++ A + GV S
Sbjct: 18 VGFIGLGSQGGPMARRIADEGYPLTIW--ARRAASVEPLAGVAAVASTPAEVGESSDVVG 75
Query: 367 I-LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 543
I + ++ V DV L DGV+A G +++ STI P +++ A ++ + DAPVS
Sbjct: 76 ICVVADADVEDVLLRADGVLAGMAAGGVVVIHSTIRPETCQRLATEAAKQEISIIDAPVS 135
Query: 544 GGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNN 702
GG A L M GG + R P+L H G +GSG VAKL NN
Sbjct: 136 GGGDAAAQRRLLVMVGGEDDAVARCRPVLETFACPVIHLGPLGSGQVAKLVNN 188
>UniRef50_A5FTT0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Alphaproteobacteria|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Acidiphilium cryptum (strain JF-5)
Length = 305
Score = 83.4 bits (197), Expect = 6e-15
Identities = 61/175 (34%), Positives = 82/175 (46%), Gaps = 1/175 (0%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKN-GVTPANSIXXXXXXXXX 357
+ VAF+GLGNMG MAA LV G V G D + A A+ G T A
Sbjct: 3 QRVAFIGLGNMGWPMAARLVGGGCEVTGCDAVEGRAEAFAREVGGTAAADADAAARGAEF 62
Query: 358 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 537
++L ++ +V V + G+LLI+ S+ P V ++I + DAP
Sbjct: 63 IVTMLPNSALVESVVAAMRPSLG---AGALLIEMSSGIPGVTRRIAAGLEAAKVAMIDAP 119
Query: 538 VSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNN 702
VSGGV A L+ M GG +D R+ LL +MG H G IG+G K NN
Sbjct: 120 VSGGVARAKTGDLSIMTGGSADDCARAETLLRLMGTTITHVGDIGAGQAMKALNN 174
>UniRef50_A0R1N4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mycobacterium smegmatis
(strain ATCC 700084 / mc(2)155)
Length = 272
Score = 83.0 bits (196), Expect = 9e-15
Identities = 53/174 (30%), Positives = 78/174 (44%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
V F+GLG+ G MA +V+ GF + +L A A +
Sbjct: 3 VGFIGLGSQGAPMARRIVEGGFETTLWARRPASLEPFADTAAKVAGTPAELAAASDLVCL 62
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+ + V +V G+ GV+A G ++ ST+ P+ +I EKG+ DAPVSG
Sbjct: 63 CVVGDDDVREVLDGETGVLAGLAPGGIIAIHSTVHPDTCTEIAEQVAEKGISLIDAPVSG 122
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXL 708
G A TL MAGG ++ ++ P+ G +GSG VAK+ NN L
Sbjct: 123 GEPAAKAGTLLVMAGGDEDIVDKVRPVFATYADPVVRLGGVGSGQVAKILNNLL 176
>UniRef50_Q98I20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Alphaproteobacteria|Rep: 3-hydroxyisobutyrate
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 305
Score = 82.6 bits (195), Expect = 1e-14
Identities = 52/176 (29%), Positives = 83/176 (47%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
++ AF+GLG++GG +A +L++ GF + +D A+ G T ANS
Sbjct: 3 ESYAFIGLGHLGGNLAPSLIRNGFAITVFDRDPAAVERLVTLGATAANSPAEAAARAGNA 62
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 540
+ L S K+ V G G++ KG I+ ST + ++ +A +G+ + PV
Sbjct: 63 ITCLPSPKISEAVLAGPGGLLEGLPKGGTWIEMSTNGRDEIMRLAALASAEGVETLECPV 122
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXL 708
+GGV A + + GG +ER + M A+ F G IGS V K+ N L
Sbjct: 123 TGGVHLAAVGKITALVGGDAALYERHRAAIEAMCARSFLMGPIGSAAVIKVITNML 178
>UniRef50_Q73P00 Cluster: 3-hydroxyacid dehydrogenase family
protein; n=4; Bacteria|Rep: 3-hydroxyacid dehydrogenase
family protein - Treponema denticola
Length = 292
Score = 82.6 bits (195), Expect = 1e-14
Identities = 53/172 (30%), Positives = 80/172 (46%)
Frame = +1
Query: 184 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 363
+V F+GLG MG MA L G + + +K + G +
Sbjct: 7 DVGFIGLGVMGKSMAERLRAAGAKMHVFTRTKKSAEEILSKGAIWYDDPASLAPNCKIIF 66
Query: 364 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 543
+I+ + V + Y G+ G++ AK G++ D +T P + K+I+ A +K DAPVS
Sbjct: 67 TIVGYPQDVEETYFGEKGLLKTAKPGTIFADMTTSSPILAKKIYDEAKKKECFSVDAPVS 126
Query: 544 GGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTN 699
GG +GA N TL+ MAGG + F+ P MG G G+G K+ N
Sbjct: 127 GGDIGAKNGTLSIMAGGDESAFKELEPFFACMGKTWALQGGAGAGQHTKMAN 178
>UniRef50_A0G5F9 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Burkholderia|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia phymatum
STM815
Length = 307
Score = 82.6 bits (195), Expect = 1e-14
Identities = 60/188 (31%), Positives = 86/188 (45%), Gaps = 1/188 (0%)
Frame = +1
Query: 148 AARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANS 327
++ +A S + F+G+G MG MA L++ G + +D + A+ G A S
Sbjct: 2 SSSQASSQQRGPLLGFVGVGTMGRPMARRLIEAGHALVVFDRDEAAVAELKAIGAQAAAS 61
Query: 328 IXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIAL 507
+ + L + + V LG DG + +L+D ST+ V K++ L
Sbjct: 62 VREIADSARIVFTSLPTPAIFRQVALG-DGGLIEGSAIKVLVDLSTVGSRVEKEVAQGLL 120
Query: 508 EKGLGFTDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCG-QIGSGXV 684
KG+ DAPVSGG GA TLA MA G E L V+G K F G + G G +
Sbjct: 121 AKGVETVDAPVSGGAAGAKKGTLAIMAAGSPVALEEVRGLFDVLG-KAFVVGDKAGQGQL 179
Query: 685 AKLTNNXL 708
KL NN L
Sbjct: 180 LKLLNNML 187
>UniRef50_Q1GF31 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding; n=17; Proteobacteria|Rep:
6-phosphogluconate dehydrogenase NAD-binding -
Silicibacter sp. (strain TM1040)
Length = 325
Score = 82.2 bits (194), Expect = 1e-14
Identities = 48/174 (27%), Positives = 78/174 (44%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ F+GLGN+GG +A +L++ GF + YD + D + + G P +
Sbjct: 3 IGFIGLGNVGGKLAGSLLRNGFDLTVYDLNPDLVAEYVEKGAQPGTGPLAIMRACDAVIT 62
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
L S V + ++ + ++ ST D K++ + E+G + PVSG
Sbjct: 63 CLPSPAACATVV---EEMLPAVDSSKIWMEMSTTDAAEVKRLAALVSERGGSAMECPVSG 119
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXL 708
G A ++ AG + FER LP L +G + H G IGS + K+ N L
Sbjct: 120 GCHRADTGNISIFAGCDRATFERMLPTLTTLGRRVLHTGDIGSASILKVMTNYL 173
>UniRef50_A0LDJ3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Magnetococcus sp. MC-1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Magnetococcus sp. (strain MC-1)
Length = 292
Score = 81.8 bits (193), Expect = 2e-14
Identities = 53/186 (28%), Positives = 82/186 (44%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
+ + F+GLG MG MA + G+ + Y+ L + A +
Sbjct: 2 QKIGFIGLGIMGSAMANSCHHAGYQLCVYNRGHARLKPFIDRSIPTAATPQALATQSDYM 61
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 540
+++ +L+V G GV + G ++I++ST+ +Q + + G F DAPV
Sbjct: 62 VIMVSDPAALLEVLQGPVGVCSADLTGKVVINASTVSVEASQQAATLVEQVGGAFLDAPV 121
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXP 720
SG + A L F+AGG +R PLL MG+ CG +G G KL N LM
Sbjct: 122 SGSKIPAQTGKLVFLAGGHHAVIQRCEPLLLSMGSAVIPCGAVGDGTRMKLAMNLLMSGM 181
Query: 721 RLAXAD 738
A A+
Sbjct: 182 VQALAE 187
>UniRef50_Q0FFH2 Cluster: Putative 2-hydroxyacid dehydrogenase; n=2;
Alphaproteobacteria|Rep: Putative 2-hydroxyacid
dehydrogenase - alpha proteobacterium HTCC2255
Length = 303
Score = 81.4 bits (192), Expect = 3e-14
Identities = 48/174 (27%), Positives = 83/174 (47%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ F+GLG MGG + NL++ G + D + G A++ +
Sbjct: 3 IGFIGLGTMGGAASLNLIRGGHQLTVCDLDLKRATKHLELGAKWADTPSEAAKDVDIVFT 62
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
++ K + + G++G++ G + +D +T P + +++ ++ G DAPV+G
Sbjct: 63 MVFGPKQIEQIIRGENGLLHSMGPGQVWVDLTTNQPELARELAQEIIDTGAIAIDAPVTG 122
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXL 708
V GA N + AGG KE ER P++ +MG + G GSG + KL +N L
Sbjct: 123 AVDGARNGNMTQFAGGDKETIERIRPVMELMGPVHY-MGSNGSGSITKLASNQL 175
>UniRef50_A0GPK7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Burkholderia|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia phytofirmans
PsJN
Length = 297
Score = 81.4 bits (192), Expect = 3e-14
Identities = 61/183 (33%), Positives = 82/183 (44%), Gaps = 4/183 (2%)
Frame = +1
Query: 175 TDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKD---ALNAAAKNGVTPANSIXXXXX 345
T + F GLG MG MA L G +R ++ S + AL A+A N V S
Sbjct: 2 TSARLGFCGLGKMGWPMAQRLADAGHALRVWNRSNEKAAALQASATNCVA-CESPAQVAA 60
Query: 346 XXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEK-GLG 522
L V V G DG+ A++G+ L+D ST+ P+ + E+ G
Sbjct: 61 GAGIVMLCLADAAAVEAVAFGVDGLANRARRGATLVDHSTLAPSQTRAFARRWREQTGGD 120
Query: 523 FTDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNN 702
+ DAPVSGG GA TLA MAGG E P+L A+ G G+G KL N
Sbjct: 121 WIDAPVSGGTSGAAAGTLAIMAGGDATLIETLTPILRGYAARVTRMGGSGAGQATKLANQ 180
Query: 703 XLM 711
++
Sbjct: 181 TIV 183
>UniRef50_Q4WV01 Cluster: Oxidoreductase, acting on the CH-OH group
of donors, NAD or NADP as acceptor; n=7;
Pezizomycotina|Rep: Oxidoreductase, acting on the CH-OH
group of donors, NAD or NADP as acceptor - Aspergillus
fumigatus (Sartorya fumigata)
Length = 435
Score = 81.4 bits (192), Expect = 3e-14
Identities = 55/182 (30%), Positives = 83/182 (45%), Gaps = 6/182 (3%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ F+GLG MG MA NLV++G+ V G+D ++ G PA+S+
Sbjct: 6 IGFVGLGAMGFGMATNLVREGYPVVGFDVFPASVQRFQSQGGIPASSLRESAEGKDFYIC 65
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG---LGFTDAP 537
++ S V V G DGVV K + L ST+ + + + +G + F D P
Sbjct: 66 MVASAPQVQSVLFGDDGVVQFLPKNATLFLCSTVPASYAQSVAAELQSRGRADIRFIDCP 125
Query: 538 VSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQ---FHCGQIGSGXVAKLTNNXL 708
VSGG A + TL+ MAG +E +L VM + G +G+G K+ + L
Sbjct: 126 VSGGAKRAADGTLSIMAGASEEALNSGREILQVMSDQNKLYLVPGGVGAGSNMKMVHQVL 185
Query: 709 MG 714
G
Sbjct: 186 AG 187
>UniRef50_O33730 Cluster: Uncharacterized oxidoreductase Sfri_1503;
n=167; Bacteria|Rep: Uncharacterized oxidoreductase
Sfri_1503 - Shewanella frigidimarina (strain NCIMB 400)
Length = 291
Score = 81.4 bits (192), Expect = 3e-14
Identities = 52/172 (30%), Positives = 83/172 (48%), Gaps = 1/172 (0%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPS-KDALNAAAKNGVTPANSIXXXXXXXXXXX 363
VAF+GLG MG MA +LVK+G V Y+ + A + G A++
Sbjct: 4 VAFIGLGVMGFPMAGHLVKQGHDVTVYNRTGAKATQWVEQYGGKKADTPKDAAQGQDIVF 63
Query: 364 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 543
+ + ++ + V LG+ G+V G++L+D +T +V ++I + F DAPVS
Sbjct: 64 TCVGNDDDLRQVVLGEHGIVHGMHAGAILVDHTTASADVAREIAAYIEPLNIAFLDAPVS 123
Query: 544 GGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTN 699
GG GA N L M GG + F+ P++ G +G+G + K+ N
Sbjct: 124 GGQAGAENGALTVMMGGDQAHFDTVKPVISAYSRCAELLGPVGAGQLTKMVN 175
>UniRef50_Q830A7 Cluster: 2-hydroxy-3-oxopropionate reductase; n=7;
Firmicutes|Rep: 2-hydroxy-3-oxopropionate reductase -
Enterococcus faecalis (Streptococcus faecalis)
Length = 296
Score = 81.0 bits (191), Expect = 3e-14
Identities = 47/175 (26%), Positives = 78/175 (44%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ F+G G MG + N++K +V Y+ +K + G ++ +
Sbjct: 4 IGFIGTGVMGKSIIRNMMKNNLSVNVYNRTKSKTDDLVAEGAVWYDTPKAIAEASDIIFT 63
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
++ V VY + G+ G +++D +T P + ++I A E G DAPVSG
Sbjct: 64 MVGFPSDVEGVYFNETGIFQADLTGKIVVDLTTSTPTLAEKIAKKAAEVGAHALDAPVSG 123
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLM 711
G +GA N TL M GG +E ++ LP+ G G G G K+ N ++
Sbjct: 124 GDLGAKNGTLTIMVGGDQESYDTVLPIFKTFGKTFMLHGSAGKGQHTKMANQLMI 178
>UniRef50_Q5LQR0 Cluster: 6-phosphogluconate dehydrogenase domain
protein; n=14; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase domain protein - Silicibacter pomeroyi
Length = 302
Score = 81.0 bits (191), Expect = 3e-14
Identities = 60/182 (32%), Positives = 85/182 (46%), Gaps = 4/182 (2%)
Frame = +1
Query: 169 SNTDK-NVAFLGLGNMGGFMAANLVKKGF--TVRGYDPSKDALNAAAKNGVTPANSIXXX 339
+N DK ++ F+GLG MG M L K G TV G + + + AA G T A
Sbjct: 4 NNMDKAHIGFIGLGLMGAAMVECLQKAGHAVTVLG-NRDRTGVEAALARGATEAAHARAV 62
Query: 340 XXXXXXXXSIL-TSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG 516
+ TS +V +Y G DGV+A ++G ++ID T P ++I KG
Sbjct: 63 AEASDIVMLCMGTSAQVESRIY-GDDGVLAGTREGQVVIDFGTSLPASTRRIGGDLAGKG 121
Query: 517 LGFTDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLT 696
+ DAP+ A + L M G K F+R P+L +G FH G +G+G KL
Sbjct: 122 ATYLDAPLGRTPAHARDGLLNIMCSGDKATFDRVKPVLHTLGENVFHLGALGNGHTIKLI 181
Query: 697 NN 702
NN
Sbjct: 182 NN 183
>UniRef50_Q8VYC5 Cluster: Fructose-bisphosphate aldolase; n=12;
cellular organisms|Rep: Fructose-bisphosphate aldolase -
Arabidopsis thaliana (Mouse-ear cress)
Length = 1373
Score = 80.2 bits (189), Expect = 6e-14
Identities = 65/204 (31%), Positives = 90/204 (44%), Gaps = 4/204 (1%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ F+GLG MG MAA+L+K F+V GYD K L G ANS
Sbjct: 324 IGFIGLGAMGFGMAAHLLKSNFSVCGYDVYKPTLVRFENAGGLAANSPAEVTKDVDVLVI 383
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALE---KGLGFTDAP 537
++T+ DV G G V G+ ++ +ST+ P Q+ LE K L DAP
Sbjct: 384 MVTNEVQAEDVLYGHLGAVEAIPSGATVVLASTVSPAFVSQL-ERRLENEGKDLKLVDAP 442
Query: 538 VSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHC-GQIGSGXVAKLTNNXLMG 714
VSGGV A L MA G E + + +L + K + G G+G K+ N L G
Sbjct: 443 VSGGVKRAAMGELTIMASGTDEALKSAGLVLSALSEKLYVIKGGCGAGSGVKMVNQLLAG 502
Query: 715 XPRLAXADCXXHGXXXMGTRTXKV 786
+ A+ G +G T K+
Sbjct: 503 VHIASAAEAMAFG-ARLGLNTRKL 525
Score = 60.5 bits (140), Expect = 5e-08
Identities = 48/192 (25%), Positives = 86/192 (44%), Gaps = 3/192 (1%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
V F+GL + +A++L++ GF V+ ++ S + + + G +S
Sbjct: 5 VGFVGLDSFSFELASSLLRSGFKVQAFEISTELVEKFIELGGHKCDSPADVGKAAAAVVV 64
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEK--GLGFTDAPV 540
+L+ + DV G +GV+ +K ++L+ SSTI +++ EK + DA V
Sbjct: 65 VLSHPDQIQDVIFGDEGVMKGLQKDAVLLLSSTISTLQLQKLEKQLTEKREQIFVVDAYV 124
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHC-GQIGSGXVAKLTNNXLMGX 717
G+ + L +A GR + R+ P L M + G+IG+G K+ N L G
Sbjct: 125 LKGMSELLDGKLMIIASGRSDSITRAQPYLTAMCQNLYTFEGEIGAGSKVKMVNELLEGI 184
Query: 718 PRLAXADCXXHG 753
+A + G
Sbjct: 185 HLVAAVEAISLG 196
>UniRef50_Q0URA2 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 325
Score = 80.2 bits (189), Expect = 6e-14
Identities = 75/217 (34%), Positives = 100/217 (46%), Gaps = 22/217 (10%)
Frame = +1
Query: 169 SNTDKNVAFLGLGNMGGFMAANLVK---KGFTVRGYDPSKDALNAAAKN--GVTPANSIX 333
S +K VAF+GLG MG MA NL K T+ D S DAL + G P +++
Sbjct: 2 SPPEKTVAFIGLGVMGYPMALNLRKGLDDSHTLLVCDVSSDALARFQNDAKGHGPVSTVD 61
Query: 334 XXXXXXXXXXSILT---SNKVVLDVYLGKD-GVVAHAKKGS------LLIDSSTIDPN-- 477
+++T + V VYL G++A A+ S L+++ TI+ +
Sbjct: 62 GGYQAVQLADTVITMLPDSNAVKKVYLDPSTGILAGAEANSGTKSDKLIMECGTIETSTI 121
Query: 478 --VPKQIFPIALEKGLGFTDAPVSGGVMGAXNATLAFMAG-GRKEDFERSLPLLXVMGAK 648
V K + L F DAPVSGG MGA + TLAFMAG K F R L MG
Sbjct: 122 LEVAKATSSSKAAENLTFVDAPVSGGPMGAQDGTLAFMAGANNKAIFPRVKGYLSHMGKP 181
Query: 649 Q--FHCGQIGSGXVAKLTNNXLMGXPRLAXADCXXHG 753
F CG IG+G K+ NN L LA ++ G
Sbjct: 182 DAIFLCGDIGAGTAFKVINNYLSAITSLAASEALNIG 218
>UniRef50_A1CAY2 Cluster: Oxidoreductase, acting on the CH-OH group
of donors, NAD or NADP as acceptor; n=2;
Aspergillus|Rep: Oxidoreductase, acting on the CH-OH
group of donors, NAD or NADP as acceptor - Aspergillus
clavatus
Length = 436
Score = 80.2 bits (189), Expect = 6e-14
Identities = 56/182 (30%), Positives = 84/182 (46%), Gaps = 6/182 (3%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ F+GLG MG MA NLV++G+ V GYD ++ G PA+S+
Sbjct: 6 IGFVGLGAMGFGMATNLVREGYPVVGYDVFPASVQRFQTAGGIPASSLRESAEGKDFYVC 65
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG---LGFTDAP 537
++ S V V G DG+V + + L ST+ + + + G + F D P
Sbjct: 66 MVASAPQVQSVLFGDDGIVQYLPPNATLFLCSTVPASYAQSVAAELQSLGRADIRFIDCP 125
Query: 538 VSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMG-AKQFHC--GQIGSGXVAKLTNNXL 708
VSGG A + TL+ MAG +E +L VM K+ + G IG+G K+ + L
Sbjct: 126 VSGGAKRAADGTLSIMAGAPEEALNSGREILQVMSDQKKLYLVPGGIGAGSNMKMVHQVL 185
Query: 709 MG 714
G
Sbjct: 186 AG 187
>UniRef50_A4SWE8 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=7; Proteobacteria|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 299
Score = 79.8 bits (188), Expect = 8e-14
Identities = 55/178 (30%), Positives = 82/178 (46%), Gaps = 3/178 (1%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSK---DALNAAAKNGVTPANSIXXXXXXXXX 357
+ F+GLG MG MA++L+ G + SK + N+AA TPA
Sbjct: 6 LGFIGLGIMGAPMASHLMAAGHALFINTRSKVPEELANSAAVVCATPAE----VAKMADI 61
Query: 358 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 537
+++ V V G+ GV KG +++D S+I P K G + DAP
Sbjct: 62 IFTMVPDTPDVEKVLFGEHGVAHGLSKGKIVVDMSSISPIATKDFAKKINALGCEYLDAP 121
Query: 538 VSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLM 711
VSGG +GA TL M GG++ F+ P+ +MG G G+G V K+ N ++
Sbjct: 122 VSGGQVGAKGGTLTIMVGGKESVFQTVKPMFDLMGKNITLVGDNGAGQVTKVANQIIV 179
>UniRef50_Q89RT2 Cluster: Bll2680 protein; n=1; Bradyrhizobium
japonicum|Rep: Bll2680 protein - Bradyrhizobium
japonicum
Length = 300
Score = 79.4 bits (187), Expect = 1e-13
Identities = 48/181 (26%), Positives = 80/181 (44%)
Frame = +1
Query: 169 SNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXX 348
++ +NVAF+G+G MG M+ + K G+ V +D S N A G++ A S
Sbjct: 2 TDASRNVAFIGIGKMGLPMSVLVAKAGYAVTAFDRSAARTNEARAQGISIAASPDDAVSG 61
Query: 349 XXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFT 528
+ L + + LG GV+A G++LI++ST+ ++ A +G+ +
Sbjct: 62 KEAVITSLPDDTALRGALLGPAGVIAAMAPGAVLIETSTVSVEASTEVAASAQARGVLYL 121
Query: 529 DAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXL 708
APVSG L G K+ F+ + PL + + G AKL N +
Sbjct: 122 RAPVSGNASIVHTGALTCFVSGPKDAFDNAKPLFAAFTRARTYLGPAEEARYAKLAVNLM 181
Query: 709 M 711
+
Sbjct: 182 I 182
>UniRef50_Q3W3N3 Cluster: Putative uncharacterized protein; n=1;
Frankia sp. EAN1pec|Rep: Putative uncharacterized
protein - Frankia sp. EAN1pec
Length = 315
Score = 79.4 bits (187), Expect = 1e-13
Identities = 50/187 (26%), Positives = 80/187 (42%)
Frame = +1
Query: 148 AARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANS 327
AA + SS ++ F+GLG+ G + G + YD D G++ A +
Sbjct: 3 AAPQGDSSLANETYGFVGLGHQGSQIVRRCASAGRHLVVYDTQTDRAEQFRPAGMSVAGT 62
Query: 328 IXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIAL 507
+ + S++ V V G G++ + GSL++ ST P + A
Sbjct: 63 LAELGRRVTVASVCVYSDEDVRTVVAGPGGLLETMRSGSLVVIHSTCSPRTCVDLAARAR 122
Query: 508 EKGLGFTDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVA 687
+G+ DAPVS G L +AGG + D +R P+ + G + G +GS +
Sbjct: 123 GRGITVLDAPVSNGAPDESGRQLVVLAGGDRRDVDRCAPVFELFGRTVVYTGDVGSAQLT 182
Query: 688 KLTNNXL 708
KL NN L
Sbjct: 183 KLVNNAL 189
>UniRef50_A6VLT0 Cluster: 2-hydroxy-3-oxopropionate reductase; n=2;
Pasteurellaceae|Rep: 2-hydroxy-3-oxopropionate reductase
- Actinobacillus succinogenes 130Z
Length = 289
Score = 79.4 bits (187), Expect = 1e-13
Identities = 50/178 (28%), Positives = 88/178 (49%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
+ V ++GLG MG MAA+L++ G V Y+ + + A G + +S+
Sbjct: 7 REVGWIGLGQMGEPMAAHLLEHGVKVGVYNRTAEKCQNVAAKGASVYSSVLELVKAYDVI 66
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 540
++ ++ V++ L ++ V A KG L+++ ST+ P +Q+ + + G F +APV
Sbjct: 67 F-VMVADFPVIESLLSEE--VLTALKGKLVVNMSTVSPTQNQQLEFLLAKHGAEFIEAPV 123
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMG 714
SG A L +A G++E E+ PL + F+ G++G KL N L+G
Sbjct: 124 SGSSKVAEAGKLLVLAAGKEEIVEQLKPLFAAFSTQTFYYGEVGKAGGVKLMINSLLG 181
>UniRef50_Q019Z7 Cluster: Oxidoreductase-like; n=1; Ostreococcus
tauri|Rep: Oxidoreductase-like - Ostreococcus tauri
Length = 325
Score = 79.4 bits (187), Expect = 1e-13
Identities = 55/191 (28%), Positives = 85/191 (44%), Gaps = 1/191 (0%)
Frame = +1
Query: 169 SNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXX 348
++T +AFLG G MG MA NL+ G V ++ ++ A + G T A +
Sbjct: 39 TSTPMKLAFLGCGIMGVPMAKNLIAAGHDVTVWNRTESATKPVVEAGATLAKTASEAARA 98
Query: 349 XXXXXSILTSNKVVLDV-YLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGF 525
++++ + L V + K+G+ G +D ST+D + I + G F
Sbjct: 99 ADVVFVMVSTPEAALAVAHAAKEGL----SSGKGYVDVSTVDAGTSRAIAEVVRSTGAEF 154
Query: 526 TDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNX 705
+APVSG A + L F+ G + + R L VMG F G +G G KL N
Sbjct: 155 LEAPVSGSKKPAEDGALIFLCAGDEGLYTRCTDPLDVMGKAHFFLGDVGQGAKMKLVVNM 214
Query: 706 LMGXPRLAXAD 738
+MG A A+
Sbjct: 215 IMGSMMGAFAE 225
>UniRef50_Q6C351 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 334
Score = 79.4 bits (187), Expect = 1e-13
Identities = 67/213 (31%), Positives = 94/213 (44%), Gaps = 17/213 (7%)
Frame = +1
Query: 151 ARRAYSSNTDKNVAFLGLGNMGGFMAANLVKK------GFTVRGYDPSKDALNAAAKNG- 309
A R ++ D + F+GLG MG MA NL KK V +D +K AL AK+
Sbjct: 12 ALRPLRASRDLSYGFIGLGRMGLPMALNLQKKLPGVDADSKVNVFDMNKAALEQIAKDKD 71
Query: 310 -----VTPANSIXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDP 474
+ S ++L V VY + K + +D STID
Sbjct: 72 PKGAQLEVLGSAVDVASKSDVIFTMLPEPVHVRGVYTDLVNNLGD-KTSKIFVDCSTIDT 130
Query: 475 NVPKQIFPIALEK--GLGFTDAPVSGGVMGAXNATLAFMAGGRKED---FERSLPLLXVM 639
+ + +K F DAPVSGGV+GA TL FM G K+ +++ LL +M
Sbjct: 131 QTSIECGKLVTDKDASAAFVDAPVSGGVVGAEKGTLTFMVGCNKDKQQVYKQVEELLKLM 190
Query: 640 GAKQFHCGQIGSGXVAKLTNNXLMGXPRLAXAD 738
G + +CG G G AKL NN L+ +A A+
Sbjct: 191 GGRIVNCGTQGQGLAAKLANNYLLAVTNVATAE 223
>UniRef50_A1WM48 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Verminephrobacter eiseniae EF01-2|Rep:
3-hydroxyisobutyrate dehydrogenase - Verminephrobacter
eiseniae (strain EF01-2)
Length = 301
Score = 79.0 bits (186), Expect = 1e-13
Identities = 53/172 (30%), Positives = 74/172 (43%)
Frame = +1
Query: 193 FLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSIL 372
F+GLGNMGG M L+ G TV +D AL A +G +S L
Sbjct: 9 FIGLGNMGGPMVKRLLHAGHTVLVFDRDAAALARAVADGAQARSSALDVADAAATIFLSL 68
Query: 373 TSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGV 552
V V +DG++ K+ ++D STI P +G+ + D+PVSGG+
Sbjct: 69 PDGPAVQHVISAQDGLL-QGKRVKCVVDLSTIGPRAAVAASQALGARGIAYVDSPVSGGI 127
Query: 553 MGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXL 708
GA TLA M + ++ P+L G + G G KL NN L
Sbjct: 128 GGAERGTLAVMTACPQPLYDELAPVLKNFGRLFYMGAGPGLGQTMKLANNLL 179
>UniRef50_P77161 Cluster: 2-hydroxy-3-oxopropionate reductase; n=99;
Proteobacteria|Rep: 2-hydroxy-3-oxopropionate reductase
- Escherichia coli (strain K12)
Length = 292
Score = 79.0 bits (186), Expect = 1e-13
Identities = 55/177 (31%), Positives = 79/177 (44%), Gaps = 2/177 (1%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFT--VRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
+ F+GLG MG MA NL + G V P D L + V A +
Sbjct: 3 LGFIGLGIMGTPMAINLARAGHQLHVTTIGPVADELLSLGAVSVETARQVTEASDIIFI- 61
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 540
++ V +V G++G + KG ++D S+I P K+ E G + DAPV
Sbjct: 62 --MVPDTPQVEEVLFGENGCTKASLKGKTIVDMSSISPIETKRFARQVNELGGDYLDAPV 119
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLM 711
SGG +GA TL+ M GG + FER PL ++G G G G K+ N ++
Sbjct: 120 SGGEIGAREGTLSIMVGGDEAVFERVKPLFELLGKNITLVGGNGDGQTCKVANQIIV 176
>UniRef50_Q5FQ06 Cluster: Putative oxidoreductase; n=1;
Gluconobacter oxydans|Rep: Putative oxidoreductase -
Gluconobacter oxydans (Gluconobacter suboxydans)
Length = 290
Score = 78.6 bits (185), Expect = 2e-13
Identities = 53/189 (28%), Positives = 81/189 (42%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ F+G G M M ANL K G+ V Y PS K+ S
Sbjct: 6 IGFIGYGAMAQRMGANLRKAGYPVVAYAPS------GGKDETEMLPSPRAIAEAAEIIIF 59
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+ ++ + G++G +A G L++D+ST+ P+ +A+E G DAP+SG
Sbjct: 60 CVPNDAAENESLHGENGALAALTPGKLVLDTSTVSPDQADAFASLAVEHGFSLLDAPMSG 119
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPRL 726
A L + GG + +R+ P+L V+G H G GS KL N +MG
Sbjct: 120 STPEAETGDLVMLVGGDEAVVKRAQPVLDVIGKLTIHAGPAGSAARLKLVVNGVMGATLN 179
Query: 727 AXADCXXHG 753
A+ +G
Sbjct: 180 VIAEGVSYG 188
>UniRef50_A6F020 Cluster: Putative uncharacterized protein; n=1;
Marinobacter algicola DG893|Rep: Putative
uncharacterized protein - Marinobacter algicola DG893
Length = 286
Score = 78.6 bits (185), Expect = 2e-13
Identities = 51/174 (29%), Positives = 80/174 (45%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
V+ +G+G+MG +A ++ KG V YD S++ + AKNG+ S+
Sbjct: 3 VSIIGVGDMGRDIAVHVRDKGHDVIAYDISEERRSDVAKNGIKVVESLAEAVAKAEVHLV 62
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
I+ +++ V ++ GS ++ +T P + + +KGLGF DAPV
Sbjct: 63 IVATDEQSETV---TREILESGPAGSTVVILATNSPKTMQVLAAECEDKGLGFVDAPVVF 119
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXL 708
G GA L + GG + + P+L H G +GSG VAK NN L
Sbjct: 120 GRQGAKEGQLGSLCGGDDKQVAKITPVLESYSKAVHHVGPVGSGQVAKACNNML 173
>UniRef50_Q13PY3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Burkholderiales|Rep: 3-hydroxyisobutyrate dehydrogenase
- Burkholderia xenovorans (strain LB400)
Length = 302
Score = 78.2 bits (184), Expect = 2e-13
Identities = 56/190 (29%), Positives = 78/190 (41%), Gaps = 1/190 (0%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ +GLGN+G A L+ G + YD +A+ G A
Sbjct: 3 IGLIGLGNIGQHFATRLLAAGHPLVVYDTRDEAMQRFGALGAELAKDTVDLASRAEVVFL 62
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
L VV +V G GV + +++D ST P+V I ++ + F APVSG
Sbjct: 63 SLPLPSVVEEVATGPHGV-SQGSSVRIVVDLSTTGPSVSNVIARKLADRHIQFLGAPVSG 121
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQ-IGSGXVAKLTNNXLMGXPR 723
G + A TL MA G E FE P L V+G F+ G G G K+ NN L
Sbjct: 122 GTVAAEKGTLTVMAAGPMEAFETVEPWLRVIGKNIFYLGSGAGLGQTMKIINNTLCAVGM 181
Query: 724 LAXADCXXHG 753
+A + G
Sbjct: 182 VASCEALVFG 191
>UniRef50_A6G049 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 307
Score = 77.8 bits (183), Expect = 3e-13
Identities = 53/184 (28%), Positives = 79/184 (42%), Gaps = 12/184 (6%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAK-----------NGVTPANSIX 333
+AFLG G MG M NL G +R Y+ +K AAA V +
Sbjct: 4 IAFLGTGTMGAGMVRNLAAAGHELRIYNRTKSRAEAAADVVADTVDLSSGGSVRVVDEPV 63
Query: 334 XXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEK 513
+ + S+ V LG+ G +A +G+L+ID T + +Q+ +
Sbjct: 64 YAARGAEFIIACVGSDAATFAVLLGEGGALAGVGQGALVIDCGTTSLKLTEQLAAACEGE 123
Query: 514 GLGFTDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQ-IGSGXVAK 690
G F DAP++G +GA L M G +E R++PL +MG H + +G G AK
Sbjct: 124 GASFLDAPITGSKLGAEGGKLTIMVAGEEEIVARAMPLFEIMGKHTVHVSERLGDGQRAK 183
Query: 691 LTNN 702
N
Sbjct: 184 YCLN 187
>UniRef50_Q2UHA9 Cluster: Predicted dehydrogenase; n=16;
Pezizomycotina|Rep: Predicted dehydrogenase -
Aspergillus oryzae
Length = 363
Score = 77.0 bits (181), Expect = 6e-13
Identities = 71/222 (31%), Positives = 105/222 (47%), Gaps = 26/222 (11%)
Frame = +1
Query: 151 ARRAYSSNT--DKNVAFLGLGNMGGFMAANL--------------VKKGFTVRGYDPSKD 282
A RA+SS+ D F+GLG MG MA NL + + R + +++
Sbjct: 30 ATRAFSSSLRRDDTWGFIGLGQMGYAMAKNLRAKIPASDTLIIRDINENTAKRFVEETQE 89
Query: 283 AL-NAAAKNGVTPANSIXXXXXXXXXXXSILTS---NKVVLDVY--LGKDGVVAHAKKGS 444
A+ N+ AK + I+TS + V +V+ + + G + +K
Sbjct: 90 AVRNSGAKEDTSKVLIAQNAREVAEQSTVIVTSLPEPEHVKNVFYCMLRHGELPALEKER 149
Query: 445 LLIDSSTIDPNVPKQIFPIALEKGLG-FTDAPVSGGVMGAXNATLAFMAGGRKEDFE--- 612
L ID+STIDP ++I G F DAP+SGGV+GA TL+FM G + E
Sbjct: 150 LFIDTSTIDPASSREIANAIHTTRQGRFVDAPMSGGVVGARAGTLSFMFGASSQTGELVD 209
Query: 613 RSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPRLAXAD 738
R +L +MG K +H G G+G AKL NN L+ +A A+
Sbjct: 210 RVQSVLMLMGKKAWHMGNSGTGVSAKLANNYLLAINNIATAE 251
>UniRef50_Q121N3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=19;
Burkholderiales|Rep: 3-hydroxyisobutyrate dehydrogenase
- Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 298
Score = 76.6 bits (180), Expect = 7e-13
Identities = 51/191 (26%), Positives = 80/191 (41%), Gaps = 1/191 (0%)
Frame = +1
Query: 184 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 363
NV +GLG MG +A L G+ V YD A+ G +++
Sbjct: 5 NVGVIGLGAMGRGIAQTLRSAGYAVHVYDVRAQAVQEFVAAGGVACDTLTQLAAACEVVV 64
Query: 364 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 543
S++ + DV + GV + K GS+ + ST+DP + G+ + DAP+S
Sbjct: 65 SVVVNAAQTEDVLWSEQGVASAMKSGSVFVMCSTVDPQWSIATEARLDKLGIHYVDAPIS 124
Query: 544 GGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQ-IGSGXVAKLTNNXLMGXP 720
GG A + M+ R +E++ +L M K + G G+G K+ N L G
Sbjct: 125 GGAAKAAAGQMTVMSSARPAAYEKAGDVLAAMAGKVYRLGDCAGAGSKVKIINQLLAGVH 184
Query: 721 RLAXADCXXHG 753
A A+ G
Sbjct: 185 IAAAAEAMALG 195
>UniRef50_A3EW86 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Leptospirillum sp. Group II UBA|Rep:
3-hydroxyisobutyrate dehydrogenase - Leptospirillum sp.
Group II UBA
Length = 279
Score = 76.2 bits (179), Expect = 1e-12
Identities = 55/169 (32%), Positives = 80/169 (47%), Gaps = 2/169 (1%)
Frame = +1
Query: 211 MGGFMAANLVKKGFTVRGYDPSKDAL--NAAAKNGVTPANSIXXXXXXXXXXXSILTSNK 384
MG M L+ G V GY+ + L + TPA+ I + ++++
Sbjct: 1 MGVRMVRRLLDNGIPVTGYNRTAGRLPSHPLFHAAHTPAD-IAEKSDLIFLMVTDGSASR 59
Query: 385 VVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAX 564
+L+ G DG+ + GSL+I+ STI P ++ L KG G+ D PVSG ++ A
Sbjct: 60 ALLE---GPDGIARGLRPGSLVINMSTIAPEEAQEEALSLLAKGAGYLDVPVSGSLVPAE 116
Query: 565 NATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLM 711
L +AGG ER+ P+L G K H G GSG AKL N L+
Sbjct: 117 KGELLLLAGGDGAALERARPILLHFGKKILHFGPTGSGMKAKLVINLLL 165
>UniRef50_Q9JYH6 Cluster: 3-hydroxyacid dehydrogenase; n=5;
Proteobacteria|Rep: 3-hydroxyacid dehydrogenase -
Neisseria meningitidis serogroup B
Length = 289
Score = 75.8 bits (178), Expect = 1e-12
Identities = 52/184 (28%), Positives = 80/184 (43%), Gaps = 1/184 (0%)
Frame = +1
Query: 166 SSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXX 345
S+N + ++GLG MG M L+ G V Y+ S D + G +
Sbjct: 2 SANEYAQIGWIGLGQMGLPMVTRLLDGGIEVGVYNRSPDKTAPISAKGAKVYGNTAELVR 61
Query: 346 XXXXXXSILTSNKVVLDVYLG-KDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLG 522
+++ V D+ G +DG+ G ++++ STI P + + G
Sbjct: 62 DYPVIFLMVSDYAAVCDILNGVRDGLA-----GKIIVNMSTISPTENLAVKALVEAAGGQ 116
Query: 523 FTDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNN 702
F +APVSG V A N TL + GG + + ++G K FH G +G G AKL N
Sbjct: 117 FAEAPVSGSVGPATNGTLLILFGGSEAVLNPLQKIFSLVGKKTFHFGDVGKGSGAKLVLN 176
Query: 703 XLMG 714
L+G
Sbjct: 177 SLLG 180
>UniRef50_Q2CHC8 Cluster: Oxidoreductase; n=1; Oceanicola granulosus
HTCC2516|Rep: Oxidoreductase - Oceanicola granulosus
HTCC2516
Length = 288
Score = 75.8 bits (178), Expect = 1e-12
Identities = 49/176 (27%), Positives = 77/176 (43%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
V +GLG MG M L ++GF R ++ + + G +S
Sbjct: 3 VGVIGLGIMGAPMVRRLRERGFETRVWNLEPERFAQVSDAGALWCDSPAGVRAASDIVVL 62
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+ + V DV G G+ A A +++D ST+ P + I A + DAPVSG
Sbjct: 63 CVLDGRAVEDVCFGAQGL-AGAGGAEIVVDCSTVPPEATRDI---AGRMDAAWIDAPVSG 118
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMG 714
G A L + GG++ D ER+ ++ + A H G +G+G AK N ++G
Sbjct: 119 GPQLAETGELTMLLGGQERDIERARAVIDALAANATHLGPLGAGQAAKTLNQAIVG 174
>UniRef50_A6VYD9 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=5; Gammaproteobacteria|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Marinomonas sp. MWYL1
Length = 300
Score = 75.8 bits (178), Expect = 1e-12
Identities = 56/191 (29%), Positives = 82/191 (42%), Gaps = 1/191 (0%)
Frame = +1
Query: 169 SNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXX 348
+N K+V +GLG+MG A + + G V G+D + AL G S
Sbjct: 2 TNKAKSVGVIGLGSMGMGAAKSCINAGLDVYGFDLNPKALEELNLAGAKAVASSALDFAD 61
Query: 349 XXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFT 528
+L N ++ L G+ A K + ++ S+TI K I + L
Sbjct: 62 QLDAVLVLVVNAKQVNSVLFDSGLAAALKPQTAVMVSATISAEDAKAIHQKLSQYQLLML 121
Query: 529 DAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCG-QIGSGXVAKLTNNX 705
DAPVSGG A + MA G E FE+ P+L AK ++ G +IG G K+ +
Sbjct: 122 DAPVSGGAAKAATGDMTVMASGSVEAFEKLQPVLDATAAKVYNIGEEIGLGATVKIIHQL 181
Query: 706 LMGXPRLAXAD 738
L G A A+
Sbjct: 182 LAGVHIAAGAE 192
>UniRef50_Q6UCZ9 Cluster: Predicted oxidoreductase; n=2;
environmental samples|Rep: Predicted oxidoreductase -
uncultured marine proteobacterium ANT32C12
Length = 309
Score = 75.4 bits (177), Expect = 2e-12
Identities = 47/172 (27%), Positives = 83/172 (48%), Gaps = 1/172 (0%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ F+GLG MG MA +L K+ + ++ S++ + A +
Sbjct: 23 IGFIGLGVMGYPMAGHLSKEFSNICIFNRSQEKVTKWLNQYSGTAFDTPEELSSQCNVIA 82
Query: 367 ILTS-NKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 543
+ ++ V ++ GK G++ G+++ID +T + K++ +AL+K + F DAP+S
Sbjct: 83 LCVGRDEDVREMMSGKKGILNSVNPGTIIIDHTTTSATLSKEMNELALQKDVIFLDAPIS 142
Query: 544 GGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTN 699
GG GA + L+ M GG K +E P+L + G GSG + K+ N
Sbjct: 143 GGQAGAESGQLSVMVGGDKASYESVKPILDNYSKFTKYMGPSGSGQLTKMVN 194
>UniRef50_Q2BFK1 Cluster: Oxidoreductase; n=1; Bacillus sp. NRRL
B-14911|Rep: Oxidoreductase - Bacillus sp. NRRL B-14911
Length = 270
Score = 75.4 bits (177), Expect = 2e-12
Identities = 51/173 (29%), Positives = 76/173 (43%), Gaps = 1/173 (0%)
Frame = +1
Query: 223 MAANLVKKGFTVR-GYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSILTSNKVVLDV 399
MA NL K G+ + ++ + G +S SIL ++K + V
Sbjct: 1 MAKNLQKNGYDLHITAHNNRKPVEELTSMGAVEHSSAADVVSNSEVIISILPADKEMESV 60
Query: 400 YLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAXNATLA 579
L ++ V+ G LI+ ++ P + K++ +KG+ D PVSGG GA N TL
Sbjct: 61 LLSEE-VLNVLNPGQFLIEMTSGSPEMMKKVHAAYQQKGIPVLDGPVSGGTAGAENGTLT 119
Query: 580 FMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPRLAXAD 738
MAGG + ER P+L M + G +G G K N L G A A+
Sbjct: 120 VMAGGDADVLERLRPVLESMATNIYLVGSVGDGKAIKAINQMLAGIHMAAAAE 172
>UniRef50_Q0UVR9 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 288
Score = 75.4 bits (177), Expect = 2e-12
Identities = 54/136 (39%), Positives = 75/136 (55%), Gaps = 6/136 (4%)
Frame = +1
Query: 364 SILTSNKVVLDVYLG-KDGVVAHAK-KGSLLIDSSTIDPNVPKQIFPIALEKGLG-FTDA 534
SI+ K V VYL K GV+A K +G L+++ STID K++ E+GLG + DA
Sbjct: 27 SIVPGGKDVKTVYLDEKTGVIAARKDEGRLMLECSTIDVESTKEVGRKLKEEGLGTYIDA 86
Query: 535 PVSGGVMGAXNATLAFMAGGRKEDFERSLP-LLXVMG--AKQFHCGQIGSGXVAKLTNNX 705
PVSGGV A TL+ + G D LP L ++G +K F+ +G+G AK++NN
Sbjct: 87 PVSGGVPAAEAGTLSMLIGAPPPDPTSLLPSTLSLLGTPSKFFYLHTLGAGLTAKISNNY 146
Query: 706 LMGXPRLAXADCXXHG 753
L G LA A+ G
Sbjct: 147 LSGTILLATAEALAIG 162
>UniRef50_Q0KC92 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1;
Ralstonia eutropha H16|Rep: 3-Hydroxyisobutyrate
dehydrogenase - Ralstonia eutropha (strain ATCC 17699 /
H16 / DSM 428 / Stanier 337)(Cupriavidus necator (strain
ATCC 17699 / H16 / DSM 428 / Stanier337))
Length = 305
Score = 74.5 bits (175), Expect = 3e-12
Identities = 46/175 (26%), Positives = 77/175 (44%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ ++G+G MG M NL+K G+ + +D A A G A + S
Sbjct: 15 LGWIGVGAMGRPMCLNLLKAGYRLTVFDRVPAQCEAVAAAGAAVAPAAQALVADSDVVFS 74
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+ + + D++L GV A + +D ST+ P+ ++ +G F APVSG
Sbjct: 75 TIFDDGGLRDLFLASGGVAGAATADKVFVDMSTVSPDASAEVAAALARRGAAFLRAPVSG 134
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLM 711
V A +A L+ G + F+ P+L + A+Q + G V KL N ++
Sbjct: 135 TVSLAASAQLSCFVSGPRPAFDAVQPVLACLTARQSYVGGADEARVIKLMINMMV 189
>UniRef50_UPI0001597301 Cluster: YfjR; n=1; Bacillus
amyloliquefaciens FZB42|Rep: YfjR - Bacillus
amyloliquefaciens FZB42
Length = 286
Score = 74.1 bits (174), Expect = 4e-12
Identities = 48/176 (27%), Positives = 83/176 (47%), Gaps = 1/176 (0%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+A +GLGNMG +A N++K G+++ Y+ +K+ G A + S
Sbjct: 3 IAIVGLGNMGRPIAENIMKAGYSLTVYNRTKEKAADLLDKGAEYAETPRQAAEHADIVLS 62
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+L+ + V DV G G++A + + I STI + +Q+ +G F APV G
Sbjct: 63 MLSDDDAVTDVTFGACGIIAGLSENGIHISMSTISTALSEQLSAAHSGRGQSFIAAPVLG 122
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCG-QIGSGXVAKLTNNXLM 711
A A L + G E +++ PLL ++ + F G + + AK++ N L+
Sbjct: 123 RPDAAEKAELRIITAGPAEAKKKAEPLLNILSQQVFDTGEETKTANAAKISVNFLL 178
>UniRef50_A1WJN2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Verminephrobacter eiseniae
(strain EF01-2)
Length = 297
Score = 74.1 bits (174), Expect = 4e-12
Identities = 51/176 (28%), Positives = 77/176 (43%), Gaps = 1/176 (0%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKK-GFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 363
+ F+GLG MG + NL +K G V +D L A +GV S
Sbjct: 9 IGFIGLGVMGEPICRNLARKSGAQVLAFDLDAAPLQRLAADGVQGQGSASAVMAQSDTVF 68
Query: 364 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 543
L S +V + +DG++A A+ G +++D T + +Q+ + F DAPV+
Sbjct: 69 LSLPSGAIVAQLCRQQDGLLASARPGHIVVDLGTSSVDGTRQLAAEFAARQAKFADAPVA 128
Query: 544 GGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLM 711
A TLA M G E F PL+ + CG +G G V K+ NN ++
Sbjct: 129 RTRAAAQAGTLAVMVGADPELFGVIEPLIATFASDIALCGPVGCGQVLKILNNMIL 184
>UniRef50_A1GFG2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Salinispora arenicola CNS205|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Salinispora arenicola CNS205
Length = 315
Score = 74.1 bits (174), Expect = 4e-12
Identities = 50/177 (28%), Positives = 76/177 (42%), Gaps = 2/177 (1%)
Frame = +1
Query: 184 NVAFLGLGNMGGFMAANLVKKG-FTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
++ LGLG MG M L+ G + ++ + +A + G A +
Sbjct: 2 HITMLGLGAMGSRMTRRLIATGEHDITVWNRTAEATRPLVEAGAVAAPTPAAATAQSDLV 61
Query: 361 XSILTSNKVVLDVYLGKD-GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 537
S+L + V+L D G + G+L +D ST+ P +++ ++G F DAP
Sbjct: 62 ISMLRDVEAGRSVWLDPDVGALTSLAPGTLAVDCSTVTPTFSRELAACCAQRGAEFLDAP 121
Query: 538 VSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXL 708
V G A TL F+AGG R P+L +G H G G+G KL N L
Sbjct: 122 VLGSRPQADAGTLIFLAGGDLAVLHRIEPVLRQVGGAVHHMGPAGTGTQMKLLTNSL 178
>UniRef50_Q7WNK6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Bordetella bronchiseptica|Rep: 3-hydroxyisobutyrate
dehydrogenase - Bordetella bronchiseptica (Alcaligenes
bronchisepticus)
Length = 306
Score = 73.7 bits (173), Expect = 5e-12
Identities = 49/175 (28%), Positives = 73/175 (41%), Gaps = 1/175 (0%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ F+GLG MGG + +L G V YD A+ AAA G PA S+
Sbjct: 9 IGFIGLGAMGGPICGHLAAAGHDVAAYDIQPAAVQAAAARGARPAASVREAADGAALLVV 68
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
++ + V G+ G A G+ + +ST+ P + + E G G D PVSG
Sbjct: 69 MVHNAGQADAVLFGEGGAAAALPAGATVWLASTVAPAYARGLQARLREHGAGLVDGPVSG 128
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCG-QIGSGXVAKLTNNXL 708
G GA L +A G+ + + P + + G + G+ KL N L
Sbjct: 129 GATGAQAGALTIIASGQAQALAAAEPAMRACSSIIHRVGEEAGAASTVKLVNQLL 183
>UniRef50_Q1EPJ1 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding domain-containing protein; n=8;
Magnoliophyta|Rep: 6-phosphogluconate dehydrogenase
NAD-binding domain-containing protein - Musa acuminata
(Banana)
Length = 314
Score = 73.7 bits (173), Expect = 5e-12
Identities = 57/188 (30%), Positives = 87/188 (46%), Gaps = 4/188 (2%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGY--DPSK-DALNAAAKNGV-TPANSIXXXXXXXX 354
V ++G G MG MAA L G+ V Y PSK D L + V +PA++
Sbjct: 18 VGWIGAGVMGAAMAARLQTAGYAVAIYARTPSKADHLRRLGAHLVPSPADAARSADVLFT 77
Query: 355 XXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 534
+ +LD G +A G +L+D ++ DP + +++ A +G DA
Sbjct: 78 MVGHPFDVREALLDP---ASGALAAIPPGGVLVDCTSSDPALAREVAAAARARGCWAVDA 134
Query: 535 PVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMG 714
PVSGG +GA + TLA +AGG + PL +G + G GSG +K+ N +G
Sbjct: 135 PVSGGDVGARDGTLAILAGGDEGVVHWLSPLFEALGRATW-MGPAGSGQSSKIANQITIG 193
Query: 715 XPRLAXAD 738
L ++
Sbjct: 194 GTILGLSE 201
>UniRef50_Q8PK98 Cluster: 3-hydroxyisobutirate dehydrogenase; n=3;
Proteobacteria|Rep: 3-hydroxyisobutirate dehydrogenase -
Xanthomonas axonopodis pv. citri
Length = 300
Score = 73.3 bits (172), Expect = 7e-12
Identities = 53/193 (27%), Positives = 77/193 (39%), Gaps = 3/193 (1%)
Frame = +1
Query: 184 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 363
++ +G+GN+G A + +G V +D AL A + G T A +
Sbjct: 2 DIGLVGMGNIGRHFVARWLAQGHRVIVHDTRAQALQQAKEAGATTAAGMADVLANAEVIA 61
Query: 364 SILTSNKVVLDVY--LGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 537
L VVL+V L + L++D ST ++ + + F AP
Sbjct: 62 LSLPLPSVVLEVARTLAAAAAATEMRDSLLVVDLSTTGAQTTSEVGHLLERADVSFLSAP 121
Query: 538 VSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHC-GQIGSGXVAKLTNNXLMG 714
VSGG A L MA G +ER+ PLL +G F+ G + G KL NN L
Sbjct: 122 VSGGTAAAAQGVLTVMAAGPLAAYERARPLLDAVGRHIFYLGGDVRLGQTLKLINNTLYA 181
Query: 715 XPRLAXADCXXHG 753
LA + G
Sbjct: 182 SAMLASCEALVCG 194
>UniRef50_Q12H32 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=1; Polaromonas sp. JS666|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 297
Score = 73.3 bits (172), Expect = 7e-12
Identities = 54/182 (29%), Positives = 84/182 (46%), Gaps = 6/182 (3%)
Frame = +1
Query: 181 KNVAFLGL-GNMGGFMAANLVKKGFTV-----RGYDPSKDALNAAAKNGVTPANSIXXXX 342
K++ +G G MG +A NL KGF + R + D L A AK +PA
Sbjct: 2 KHIGMIGASGLMGHGIARNLQAKGFDLSLTVHRNTERVADLLAAGAKQVASPAG-----L 56
Query: 343 XXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLG 522
+T + V G DGV++ A G ++ID+ST +P +++ + E+G+
Sbjct: 57 GDCDAVIICVTGSPQVEQTLSGPDGVLSRALAGLIVIDTSTSEPESTRRLAALCAERGVT 116
Query: 523 FTDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNN 702
DAP++ + A L M G + F++ P+L FH G G+G V KL NN
Sbjct: 117 LVDAPLARTPVEAELGRLNTMVGAEQAVFDKIRPVLAAYCENIFHVGGPGAGHVIKLLNN 176
Query: 703 XL 708
+
Sbjct: 177 FI 178
>UniRef50_Q55JR1 Cluster: Putative uncharacterized protein; n=2;
Filobasidiella neoformans|Rep: Putative uncharacterized
protein - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 605
Score = 72.9 bits (171), Expect = 9e-12
Identities = 46/139 (33%), Positives = 71/139 (51%), Gaps = 3/139 (2%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
V ++GLG MG MAA+LV +G+ V+ +D +L A+ G P++S
Sbjct: 9 VGWIGLGAMGSGMAASLVSQGYKVQAFDVYPPSLKRVAEQGAIPSSSPRDAAEGVQVLCL 68
Query: 367 ILTSNKVVLDVYLGKDGVVAH-AKKGSLLIDSSTIDPNVPKQIFP--IALEKGLGFTDAP 537
++ + + V + GKDG VA K G+ +I ST+ P+ ++ L K +G D+P
Sbjct: 69 MVVNAQQVEETLFGKDGGVAEILKNGASIIVFSTVPPSFLVEVARRLDKLGKNIGLVDSP 128
Query: 538 VSGGVMGAXNATLAFMAGG 594
VSGG A LA M+ G
Sbjct: 129 VSGGSTRAAQGQLAIMSSG 147
>UniRef50_O66454 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Aquifex aeolicus
Length = 288
Score = 72.5 bits (170), Expect = 1e-11
Identities = 48/177 (27%), Positives = 82/177 (46%), Gaps = 1/177 (0%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKN-GVTPANSIXXXXXXXXXXX 363
V F+GLG++G +A L+++G + ++ + + AK G +S
Sbjct: 3 VGFIGLGHLGRAIAKRLIEQGVELIVWNRTLSKAHEFAKETGAEVTSSPADLINKVDRVF 62
Query: 364 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 543
I+ ++ +V G+ G+V KG +ID +T ++ + + G + DAPV
Sbjct: 63 VIVFDSQASEEVIFGEKGLVKGDIKGKTVIDMTTNHYLYAQKAYEELKKLGAFYLDAPVL 122
Query: 544 GGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMG 714
G V+ A L + GG KE FE + PL ++ G+ G G KL NN ++G
Sbjct: 123 GSVIPALKGELTIVVGGDKEKFEENKPLFEKFCRAIYYLGEAGMGSKMKLVNNIVLG 179
>UniRef50_Q3WJ00 Cluster: 6-phosphogluconate dehydrogenase, NAD
binding domain; n=1; Frankia sp. EAN1pec|Rep:
6-phosphogluconate dehydrogenase, NAD binding domain -
Frankia sp. EAN1pec
Length = 438
Score = 72.5 bits (170), Expect = 1e-11
Identities = 55/193 (28%), Positives = 79/193 (40%)
Frame = +1
Query: 160 AYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXX 339
+Y F+GLG+MG MA L +G + Y +L A T A +
Sbjct: 163 SYHDEDTVKTGFIGLGSMGLPMAQRLQSQGHDLTLYARRPASLEPFAGTSATIAATPAEM 222
Query: 340 XXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGL 519
+ V +V G DG+ G++++ ST+ P ++I A GL
Sbjct: 223 GASVDAVGICVFDAAGVEEVMFGPDGLAGTLNPGAVVLVHSTVAPAQIRRIAGRAATHGL 282
Query: 520 GFTDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTN 699
DAPVSGG A L M GG + LL + H G +G+G AKL N
Sbjct: 283 RVLDAPVSGGQPRALAGELTIMIGGDADTLADVAELLSALSNHVVHLGAVGAGSYAKLIN 342
Query: 700 NXLMGXPRLAXAD 738
N + ++A AD
Sbjct: 343 NTMFA-AQIALAD 354
>UniRef50_Q20XN2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Rhodopseudomonas palustris BisB18|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Rhodopseudomonas palustris (strain BisB18)
Length = 365
Score = 72.5 bits (170), Expect = 1e-11
Identities = 53/175 (30%), Positives = 80/175 (45%), Gaps = 1/175 (0%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
V +GLG MG A NL+ G + +D + ++A A+ GV A + S
Sbjct: 23 VGVVGLGRMGRAFAENLLADGHPIVVWDAFQTQIDAMARPGVVAATKLADLAECDVVFSS 82
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
L ++ V V G G+V K G++ I STI P + +++ E G G+ APV G
Sbjct: 83 -LPDDEAVTAVAAGAGGLVKIMKAGAVHISMSTISPTMSRRLAAWHGECGQGYVAAPVLG 141
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQ-IGSGXVAKLTNNXL 708
A TL +A G +++ PLL +G K F G+ + + KL N L
Sbjct: 142 NPDLARARTLFILAAGPDAAMQKARPLLDRLGQKLFVIGEDAAAANLVKLAGNVL 196
>UniRef50_A2C1U6 Cluster: 3-hydroxyisobutyrate dehydrogenase and
related beta-hydroxyacid dehydrogenases; n=2;
Prochlorococcus marinus|Rep: 3-hydroxyisobutyrate
dehydrogenase and related beta-hydroxyacid
dehydrogenases - Prochlorococcus marinus (strain NATL1A)
Length = 287
Score = 72.5 bits (170), Expect = 1e-11
Identities = 51/189 (26%), Positives = 81/189 (42%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+AF+GLG +G M+ L+ G+ + Y +K ++ K P ++
Sbjct: 3 LAFIGLGAIGKPMSQRLIDNGYDLNLYQRNKLNNDSKRKYFFDPIEAVSDCDGLLIC--- 59
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+T + V V G +GV K S +ID STI P+ I E+ + + D PVSG
Sbjct: 60 -VTDDNAVESVLFGDNGVSGSLKPNSFVIDFSTISPDKSISIHKRLGEQNIFYVDCPVSG 118
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPRL 726
G GA N +L+ G ++D + V+G + +G G K N L+
Sbjct: 119 GTEGAHNGSLSLFIGASEKDCLSFENIFQVLGKSINYFNGVGKGQQVKALNQILVAGTYA 178
Query: 727 AXADCXXHG 753
A A+ G
Sbjct: 179 AVAEAMELG 187
>UniRef50_Q7VYY0 Cluster: Putative oxidoreductase; n=4;
Bordetella|Rep: Putative oxidoreductase - Bordetella
pertussis
Length = 305
Score = 72.1 bits (169), Expect = 2e-11
Identities = 55/194 (28%), Positives = 86/194 (44%), Gaps = 8/194 (4%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLV-KKGFTVRGYDPSKDALNAAAKNGV----TPANSIXXXXX 345
+ + F+GLG MG M NL + + + YD S A + A +
Sbjct: 3 QTLGFVGLGMMGLPMLENLAGDERWQILAYDRSPAPFERLAGHPAWGKRLRAAAGLQELA 62
Query: 346 XXXXXXSILTSNKVVLDVYLGKDG---VVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG 516
++L ++ + V LG DG ++ + G+ ++D + +P +++ +G
Sbjct: 63 ACDTVITMLPNSAITNAVVLGGDGQPGLIDLLESGAAIVDMGSSNPADTRRLSEQLAARG 122
Query: 517 LGFTDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLT 696
L DAPVSG V A TLA MAG + D R P+L MGA H G +GS K
Sbjct: 123 LTLIDAPVSGAVAKASTGTLAIMAGAAEADLRRVRPILERMGAAIIHTGAVGSAHAMKAL 182
Query: 697 NNXLMGXPRLAXAD 738
NN + LA ++
Sbjct: 183 NNYVYAAGLLAVSE 196
>UniRef50_A4ECY9 Cluster: Putative uncharacterized protein; n=1;
Collinsella aerofaciens ATCC 25986|Rep: Putative
uncharacterized protein - Collinsella aerofaciens ATCC
25986
Length = 359
Score = 72.1 bits (169), Expect = 2e-11
Identities = 50/185 (27%), Positives = 79/185 (42%)
Frame = +1
Query: 184 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 363
+VAF+G G MG +A +++ G+ V + +K A + G A +
Sbjct: 6 SVAFIGTGIMGAPIAGHILDAGYPVTVNNRTKSKAAALIERGAVWAETPADAVVNADVVF 65
Query: 364 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 543
+++ V ++YL DG++ K G++LID +T P + + I A G D PV+
Sbjct: 66 TMVGYPSEVEELYLAGDGLLTCTKPGAVLIDLTTSSPELARDIAEAAQVSGRMAFDCPVT 125
Query: 544 GGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPR 723
GG GA TL + G + D +L A G G AKL N +
Sbjct: 126 GGESGAIAGTLTAIVGATENDIAPVRDVLSTFAANICCFDGAGKGQAAKLANQVSLAACM 185
Query: 724 LAXAD 738
+ AD
Sbjct: 186 VGMAD 190
>UniRef50_Q9LNP0 Cluster: F1L3.35; n=8; Magnoliophyta|Rep: F1L3.35 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 387
Score = 72.1 bits (169), Expect = 2e-11
Identities = 38/116 (32%), Positives = 59/116 (50%)
Frame = +1
Query: 391 LDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAXNA 570
+DV GK+G + G +D ST+D I + G F +APVSG A +
Sbjct: 166 IDVACGKNGAIFGISSGKGYVDVSTVDVASSILISKQIKDTGALFLEAPVSGSKKPAEDG 225
Query: 571 TLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPRLAXAD 738
L F+ G K +E++ P L +MG +F+ G++G+G KL N +MG + A+
Sbjct: 226 QLIFLTAGDKPLYEKAAPFLDIMGKSKFYLGEVGNGAAMKLVVNMIMGSMMASFAE 281
>UniRef50_Q3W9W7 Cluster: 6-phosphogluconate dehydrogenase, NAD
binding domain; n=2; Frankia sp. EAN1pec|Rep:
6-phosphogluconate dehydrogenase, NAD binding domain -
Frankia sp. EAN1pec
Length = 286
Score = 71.7 bits (168), Expect = 2e-11
Identities = 53/194 (27%), Positives = 88/194 (45%), Gaps = 1/194 (0%)
Frame = +1
Query: 175 TDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXX 354
T +V F+GLGNMGG +AAN+ + G + +D + A G T + +
Sbjct: 2 TAPSVGFVGLGNMGGALAANVAQFGLDLVVHDAAGPE---RAPEGTTHLDDLAAVARHAE 58
Query: 355 XXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 534
+L+ V+ + + ++ + ++D+STI + ++I + G+G+ DA
Sbjct: 59 VV--VLSLPDGVISEKVARGLAETADRRVTHVVDTSTIGVSAAQRITDLLAASGIGYVDA 116
Query: 535 PVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCG-QIGSGXVAKLTNNXLM 711
PVSGGV GA TL M G + R P+L + ++ G + G KL NN L
Sbjct: 117 PVSGGVTGARARTLTVMYAGTDDACARVEPVLAALSDRRRRVGDRPGLAQALKLANNFLA 176
Query: 712 GXPRLAXADCXXHG 753
A ++ G
Sbjct: 177 AVALAATSEAVAFG 190
>UniRef50_A7H7Z5 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding; n=2; Anaeromyxobacter|Rep:
6-phosphogluconate dehydrogenase NAD-binding -
Anaeromyxobacter sp. Fw109-5
Length = 293
Score = 71.7 bits (168), Expect = 2e-11
Identities = 54/178 (30%), Positives = 77/178 (43%), Gaps = 2/178 (1%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKG--FTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
+ F+GLG +G +A NL K G TV PSK A + +K G A S
Sbjct: 5 IGFVGLGTIGEPIANNLRKAGHDLTVWNRTPSK-AAHIVSKGGKL-AGSARECATGRDLV 62
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 540
+ ++ K + V G DGV+ + G +L+D ST + + A +G GF PV
Sbjct: 63 ITCVSDEKALDTVLEGPDGVLEALRDGDVLVDMSTAGVRAARSVSERAAARGAGFVACPV 122
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMG 714
G A A L +AGG ER+ P L + A+ F + KL N + G
Sbjct: 123 LGSRSAAEQAQLVLVAGGPAVARERARPALHAVSARIFELEDAAQAALMKLCVNAIGG 180
>UniRef50_Q98K09 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7;
Alphaproteobacteria|Rep: 3-hydroxyisobutyrate
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 312
Score = 71.3 bits (167), Expect = 3e-11
Identities = 51/178 (28%), Positives = 77/178 (43%), Gaps = 2/178 (1%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGF--TVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXX 354
+ + F+GLG MG +A N+V KG+ T G K A + + G A++
Sbjct: 8 EKIGFIGLGLMGHGIAKNIVDKGYPLTFLGRKNRKPAEDLLGR-GAREASTSRDVAVASD 66
Query: 355 XXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 534
+T ++ V + G G+ KKGS+++D ST DP + G+ + DA
Sbjct: 67 IVFICVTGSREVEAIIRGPGGLKEGLKKGSVVVDCSTSDPVSTVALAAELKALGIDYVDA 126
Query: 535 PVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXL 708
P+S A TL M G F R P++ + H G G G KL NN +
Sbjct: 127 PLSRTPKEAWEGTLDAMVGAPDAVFARVKPVIETWAGRIVHIGDTGDGHRMKLLNNFI 184
>UniRef50_Q46TQ0 Cluster: UDP-glucose/GDP-mannose
dehydrogenase:Prephenate dehydrogenase:NADP
oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Ralstonia eutropha JMP134|Rep:
UDP-glucose/GDP-mannose dehydrogenase:Prephenate
dehydrogenase:NADP oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding - Ralstonia eutropha (strain JMP134)
(Alcaligenes eutrophus)
Length = 294
Score = 71.3 bits (167), Expect = 3e-11
Identities = 48/175 (27%), Positives = 76/175 (43%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ F+G G MG MA ++ G V YD + + +AA G+ A S+ S
Sbjct: 3 IGFIGTGKMGLPMARHIAAAGHDVVAYDIAPEQASAARHAGLAVAPSLADAVSAAEVIFS 62
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+ N G+ + A+ G+L ID+ST+ P + P+ + + + VSG
Sbjct: 63 SMP-NDGAFSAVAGQ--IAKAARPGALYIDTSTVSPAASAAVAPLLAARDIAYLRVTVSG 119
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLM 711
A A L + G + +ER PLL +G QF+ G + KL N L+
Sbjct: 120 NNHMAEAAKLTALVSGPADAYERIKPLLAALGPAQFYLGDAEQARLMKLVVNLLI 174
>UniRef50_Q9LM23 Cluster: Fructose-bisphosphate aldolase; n=2;
Arabidopsis thaliana|Rep: Fructose-bisphosphate aldolase
- Arabidopsis thaliana (Mouse-ear cress)
Length = 1486
Score = 71.3 bits (167), Expect = 3e-11
Identities = 66/213 (30%), Positives = 91/213 (42%), Gaps = 13/213 (6%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPS---------KDALNAAAKNGVTPANSIXXX 339
+ F+GLG MG MAA+L+K F+V GYD S K L G ANS
Sbjct: 348 IGFIGLGAMGFGMAAHLLKSNFSVCGYDISLRLAVSSVYKPTLVRFENAGGLAANSPAEV 407
Query: 340 XXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALE--- 510
++T+ DV G G V G+ ++ +ST+ P Q+ LE
Sbjct: 408 TKDVDVLVIMVTNEVQAEDVLYGHLGAVEAIPSGATVVLASTVSPAFVSQL-ERRLENEG 466
Query: 511 KGLGFTDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHC-GQIGSGXVA 687
K L DAPVSGGV A L MA G E + + +L + K + G G+G
Sbjct: 467 KDLKLVDAPVSGGVKRAAMGELTIMASGTDEALKSAGLVLSALSEKLYVIKGGCGAGSGV 526
Query: 688 KLTNNXLMGXPRLAXADCXXHGXXXMGTRTXKV 786
K+ N L G + A+ G +G T K+
Sbjct: 527 KMVNQLLAGVHIASAAEAMAFG-ARLGLNTRKL 558
Score = 33.5 bits (73), Expect = 6.9
Identities = 22/76 (28%), Positives = 33/76 (43%), Gaps = 1/76 (1%)
Frame = +1
Query: 529 DAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHC-GQIGSGXVAKLTNNX 705
DA V G+ + L +A GR + R+ P L M + G+IG+G K+ N
Sbjct: 145 DAYVLKGMSELLDGKLMIIASGRSDSITRAQPYLTAMCQNLYTFEGEIGAGSKVKMVNEL 204
Query: 706 LMGXPRLAXADCXXHG 753
L G +A + G
Sbjct: 205 LEGIHLVAAVEAISLG 220
>UniRef50_Q74D68 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=7; Desulfuromonadales|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Geobacter sulfurreducens
Length = 288
Score = 70.9 bits (166), Expect = 4e-11
Identities = 54/191 (28%), Positives = 74/191 (38%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
+ V FLGLG +G MAANL+K + + YD A+ A G T A +
Sbjct: 3 RKVGFLGLGTVGRHMAANLLKGNYELAVYDSDPAAVADLAALGATGAATPREVAKGRDIV 62
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 540
I + + G DG+ A G++L+D T ++ A + + F DAPV
Sbjct: 63 IHIRPEKERLRPDIYGPDGIFAGIDPGTILVDMGTHSLTSTMEMADEAAKHRVMFLDAPV 122
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXP 720
G A N L +AGG R L G H G IG K N +
Sbjct: 123 WGTKEHAANGLLTILAGGDPSLVGRCRELFSFFGLNIIHVGSIGDATRMKFVVNLVQAEL 182
Query: 721 RLAXADCXXHG 753
A A+ G
Sbjct: 183 MQALAESIVFG 193
>UniRef50_A3LTC4 Cluster: 3-hydroxyisobutyrate dehydrogenase-like
protein; n=6; Saccharomycetales|Rep:
3-hydroxyisobutyrate dehydrogenase-like protein - Pichia
stipitis (Yeast)
Length = 355
Score = 70.9 bits (166), Expect = 4e-11
Identities = 71/230 (30%), Positives = 103/230 (44%), Gaps = 30/230 (13%)
Frame = +1
Query: 139 LYTAAR---RAYSSNT--DKNVAFLGLGNMGGFMAANLVKK-------------GFTVRG 264
+Y A+R R +SS + + F+GLG MG MA ++ K +
Sbjct: 1 MYKASRICTRHFSSTSMASTSYGFIGLGQMGQHMARHIYNKLEATDKLYVNDNVAAATQS 60
Query: 265 YDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS-ILTSNKVVLDVYLGKDGVVAHAKKG 441
+ + N A K+ + P NS+ I+T V +V+H +K
Sbjct: 61 FIKNVTDENPANKDALKPLNSLEEFVTSVDEPLDFIITMVPEGKHVKGVVSELVSHYQKN 120
Query: 442 SL------LIDSSTIDPNVPKQIFPIALEK--GLGFTDAPVSGGVMGAXNATLAFM-AGG 594
++ +DSSTID +++ ++ G F D PVSGGV GA ATL+FM +
Sbjct: 121 NVSGTKTTFLDSSTIDIPTSREVHEFVKKELPGADFIDTPVSGGVAGARKATLSFMLSRP 180
Query: 595 RKEDFERSL-PLLXVMGAKQFHCGQI-GSGXVAKLTNNXLMGXPRLAXAD 738
E L LL MGA F CG+ G+G AKL+NN L+ LA AD
Sbjct: 181 NNESISADLRTLLNKMGANIFACGETHGAGLAAKLSNNYLLAVTNLAVAD 230
>UniRef50_A3H9B3 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Caldivirga maquilingensis IC-167|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Caldivirga maquilingensis IC-167
Length = 293
Score = 70.9 bits (166), Expect = 4e-11
Identities = 43/141 (30%), Positives = 67/141 (47%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
V +GLG MGG L+ KGF + YD +D +N K G T A+S +
Sbjct: 3 VGLVGLGRMGGAFGRVLLSKGFNLVVYDVVRDKVNEFVKLGATGASSPADLASRVDIVLT 62
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+ ++ VLDVYLG +G+++ AK G + +++ST D ++ + +GF A +
Sbjct: 63 NVPRSEDVLDVYLGGNGILSGAKPGLIAVETSTTDIKTKLRVAEECRRRNVGFIVAMLGK 122
Query: 547 GVMGAXNATLAFMAGGRKEDF 609
V A GG +E F
Sbjct: 123 TVPQAERGETPLFVGGPEEVF 143
>UniRef50_P71825 Cluster: Uncharacterized oxidoreductase
Rv0770/MT0794; n=18; Corynebacterineae|Rep:
Uncharacterized oxidoreductase Rv0770/MT0794 -
Mycobacterium tuberculosis
Length = 295
Score = 70.9 bits (166), Expect = 4e-11
Identities = 48/174 (27%), Positives = 73/174 (41%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ ++GLGN G MA L+ + +D +A+ + G T A S+ +
Sbjct: 10 LGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAEADIISIT 69
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+ +V V +G+ HAK G+++ STI + +G+ DAPVSG
Sbjct: 70 VFDDAQVS-SVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVSG 128
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXL 708
G A LA M G E F+R + H G+ G+G KL N L
Sbjct: 129 GAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNML 182
>UniRef50_A0R1N5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mycobacterium smegmatis
(strain ATCC 700084 / mc(2)155)
Length = 263
Score = 70.5 bits (165), Expect = 5e-11
Identities = 50/175 (28%), Positives = 72/175 (41%), Gaps = 1/175 (0%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTP-ANSIXXXXXXXXXXX 363
+ FLG G MG M L G V + + A A +G TP A +
Sbjct: 3 IGFLGAGRMGAPMVQRLTAAGHDVHALGRTDEKRTAVAGSGATPVAAATDAVHGADVVIV 62
Query: 364 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 543
+ T +V L D ++ G++L+ +T P + I A ++G+ DAPVS
Sbjct: 63 CVFTDEQVRT---LCTDTLLDAMAPGAVLVLHTTGSPRTAEDIAARAADRGVAVVDAPVS 119
Query: 544 GGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXL 708
GG ++ AGG + ER P L H G +GSG KL NN +
Sbjct: 120 GGPHDIAAGSVTVFAGGDADVVERVRPALVAYAEPLLHVGPLGSGQRVKLVNNTM 174
>UniRef50_Q9HLR4 Cluster: Putative uncharacterized protein Ta0161;
n=2; Thermoplasma|Rep: Putative uncharacterized protein
Ta0161 - Thermoplasma acidophilum
Length = 290
Score = 69.7 bits (163), Expect = 9e-11
Identities = 55/192 (28%), Positives = 80/192 (41%), Gaps = 1/192 (0%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKD-ALNAAAKNGVTPANSIXXXXXXXXX 357
K V +GLG MG +AAN G YD + D A N A+ V +
Sbjct: 8 KKVLLVGLGVMGSRIAANFASAGKLAGVYDRNVDKAKNTASMLKVGFYRDLGEAVKNSDI 67
Query: 358 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 537
++L ++ V +VY + V +G + ID STI P+ +I EKG DAP
Sbjct: 68 IVTMLYDDRSVKEVYSQMEQGV----QGKVFIDMSTISPDTSIEIAKRIKEKGGKMYDAP 123
Query: 538 VSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGX 717
V G + L + GG ++ L+ + + G GSG AKL NN +G
Sbjct: 124 VIGTSIAVEKKALVVLVGGDLSGYDEVRDLISATANQVVYMGDNGSGLYAKLVNNLFLGS 183
Query: 718 PRLAXADCXXHG 753
+ A+ G
Sbjct: 184 YMASLAEAVRFG 195
>UniRef50_Q5LNV6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Rhodobacteraceae|Rep: 3-hydroxyisobutyrate dehydrogenase
- Silicibacter pomeroyi
Length = 269
Score = 69.3 bits (162), Expect = 1e-10
Identities = 49/174 (28%), Positives = 75/174 (43%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ G G MG M A L + GF +G+D + +G+T + + +
Sbjct: 2 IGVAGCGRMGAPMLAALRRAGFQAQGFDIRPSSDFPGTDHGIT--DGVAVFSQNLCTLIT 59
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
++ V L D + HAK +I ST+ P + + + + DAP+SG
Sbjct: 60 VVRDISQTEQV-LFTDQKLIHAKHLDCVIICSTLSPRYVRDL-RARVPDHIALIDAPMSG 117
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXL 708
+ A A L+FM GG D + + PL MG+ G GSG AK+ NN L
Sbjct: 118 AQIAAQEARLSFMLGGEPADLDAAQPLFAAMGSHFHRMGPYGSGMQAKVLNNLL 171
>UniRef50_A1UJF3 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Actinomycetales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Mycobacterium sp. (strain KMS)
Length = 272
Score = 69.3 bits (162), Expect = 1e-10
Identities = 49/173 (28%), Positives = 73/173 (42%), Gaps = 1/173 (0%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGV-TPANSIXXXXXXXXXXX 363
V F+G G MG M LV G TV + + AA+ G T A +
Sbjct: 4 VGFVGAGRMGAPMVRRLVGAGHTVTALGRTPEKRAAASDLGAATAAEPVDVATGADIVVV 63
Query: 364 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 543
+ T ++V G G++A G+ L+ +T P+ + + + G+ DAPVS
Sbjct: 64 CVFTDDQVRAVCLDG--GLLAAMAPGATLVIHTTGSPDTARLLAARGRDHGVDVVDAPVS 121
Query: 544 GGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNN 702
GG + GG + ER+ P+L G H G +G+G KL NN
Sbjct: 122 GGPHDIAAGAVTLFVGGSEAAVERARPVLAAYGDPILHVGPLGAGQSVKLVNN 174
>UniRef50_A7RG59 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 341
Score = 69.3 bits (162), Expect = 1e-10
Identities = 52/199 (26%), Positives = 89/199 (44%)
Frame = +1
Query: 112 ARTILSTQCLYTAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALN 291
AR + L+ AA +S + + V +G GN+G +A L K +V+ +D ++ N
Sbjct: 4 ARFLARNAFLWRAAFSMSTSASPRTVGLVGTGNVGSAVAVGLRKIDVSVKAFDLQQNNYN 63
Query: 292 AAAKNGVTPANSIXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTID 471
G T NS + L + V L G+++ K+GS+ ID +T D
Sbjct: 64 FLESTGTTLVNSPEEVTKDVDVLITALPKPQHVKSA-LEDTGMLSMLKEGSVWIDHTTTD 122
Query: 472 PNVPKQIFPIALEKGLGFTDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQ 651
N ++ +A KG+ +AP++GG + GG ++ + PL+ A
Sbjct: 123 YNETIRLGELATSKGVHAVEAPLTGG-----QGLMTVFVGGEEKVVQDVKPLMDSYTATF 177
Query: 652 FHCGQIGSGXVAKLTNNXL 708
+ G +G VAK+ +N L
Sbjct: 178 LYFGPLGKATVAKVISNML 196
>UniRef50_Q39KK8 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=34; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia sp. (strain
383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
/ R18194))
Length = 289
Score = 68.1 bits (159), Expect = 3e-10
Identities = 47/174 (27%), Positives = 81/174 (46%), Gaps = 1/174 (0%)
Frame = +1
Query: 184 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 363
++ F+GLG MG +A NL+K G TVR ++ S++ A G ++
Sbjct: 2 DLGFIGLGEMGQAIATNLLKAGHTVRVWNRSRERAEPLAAIGAQIVDT-PADAFRGDAVF 60
Query: 364 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 543
S+L + ++ D ++A A +G + ++ +T+ + + + +G+ + APV
Sbjct: 61 SMLADDAAARAIF--DDALLAQAPRGLIHVNMATVSVALAESLAHAHASRGIHYVAAPVM 118
Query: 544 GGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGS-GXVAKLTNN 702
G A A L MAGG E +R PL +G K + G + VAK+ N
Sbjct: 119 GRPDVAAAARLTIMAGGPAEAIDRVQPLFDAIGQKTWRFGSLPQHANVAKIAAN 172
>UniRef50_A5WG80 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Moraxellaceae|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Psychrobacter sp. PRwf-1
Length = 309
Score = 68.1 bits (159), Expect = 3e-10
Identities = 54/175 (30%), Positives = 76/175 (43%)
Frame = +1
Query: 184 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 363
+V+F+GLG MG MA +LV TV Y+ + D A A T A S+
Sbjct: 17 SVSFIGLGAMGHHMAKHLVGSFDTVMVYNRNFDKATAHAAEFGTQAVSLEQAVSADVIF- 75
Query: 364 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 543
S L +++VV D+ + + H GS+ +D ++ P K G F DAPVS
Sbjct: 76 SCLPTSQVVDDLI---EQALPHLNDGSVWVDCTSGVPENAKASQAKLNAAGCEFLDAPVS 132
Query: 544 GGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXL 708
G GA + TL M GG + + + H G G+G K NN L
Sbjct: 133 GQTSGADSGTLTVMVGGSAKALAYAKSAIDCFAGLIVHVGDSGAGFAVKAVNNTL 187
>UniRef50_Q4Q9Z1 Cluster: Dehydrogenase-like protein; n=6;
Trypanosomatidae|Rep: Dehydrogenase-like protein -
Leishmania major
Length = 431
Score = 68.1 bits (159), Expect = 3e-10
Identities = 53/200 (26%), Positives = 86/200 (43%), Gaps = 15/200 (7%)
Frame = +1
Query: 184 NVAFLGLGNMGGFMAANLVKKGFTV-------RGYDPSKDALNAAAKNGVTPANSIXXXX 342
NV +G+GNMG + NL K + R ++ + + +G T A I
Sbjct: 9 NVGVVGMGNMGIPITRNLAFKARSAMYLQIHSRTLSKARQVCDDMSADGATCAMRIHDRY 68
Query: 343 XXXXXXXSIL--------TSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFP 498
++ S KV+L+ + +V +A+ G +++D +T+D + ++
Sbjct: 69 STMTKWCDVILLTLAHRAASRKVLLE---DSEALVTNARPGQIIVDHTTVDMELSRECAH 125
Query: 499 IALEKGLGFTDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSG 678
A +G F DAP+SG A N L M GG E +R P+ + H G GSG
Sbjct: 126 EAERRGAVFLDAPMSGSPKQAFNNQLVLMVGGPAEQVQRVSPIFRMYADHIHHMGANGSG 185
Query: 679 XVAKLTNNXLMGXPRLAXAD 738
AKL + L+ A A+
Sbjct: 186 TAAKLLSQALVASHNAAAAE 205
>UniRef50_Q0RIL5 Cluster: Putative uncharacterized protein; n=1;
Frankia alni ACN14a|Rep: Putative uncharacterized
protein - Frankia alni (strain ACN14a)
Length = 493
Score = 67.7 bits (158), Expect = 3e-10
Identities = 44/169 (26%), Positives = 82/169 (48%)
Frame = +1
Query: 196 LGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSILT 375
+GLG +GG +A ++ ++G +D DA A G + +++T
Sbjct: 13 VGLGMIGGGVAVSMARRGRVPAVHDVRPDASAALPGVGDPLGSPAEVARSSDVVMVAVVT 72
Query: 376 SNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVM 555
+++ DV G++G++A A G ++ ST++ V ++ + E +GF D V+ G
Sbjct: 73 ADQA-RDVIGGENGLLAGAHPGLTIVLLSTVELAVVHELAALCAEHDVGFLDCGVTPGDR 131
Query: 556 GAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNN 702
A + +A + GG + E + P+L + HCG +G+G V K+ N
Sbjct: 132 AADHGMVA-IVGGDEATVEAARPVLDDWARRVVHCGPLGAGMVTKIARN 179
>UniRef50_Q033P2 Cluster: 3-hydroxyisobutyrate dehydrogenase related
beta-hydroxyacid dehydrogenase; n=1; Lactobacillus casei
ATCC 334|Rep: 3-hydroxyisobutyrate dehydrogenase related
beta-hydroxyacid dehydrogenase - Lactobacillus casei
(strain ATCC 334)
Length = 285
Score = 67.7 bits (158), Expect = 3e-10
Identities = 51/175 (29%), Positives = 81/175 (46%), Gaps = 3/175 (1%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ F+G+G+MG M +L K G+ V +D + A A + V A S+ +
Sbjct: 3 ITFIGVGDMGSHMVPHLAKAGYDVTVWDKVPAKMAAVAGDHVRTATSLEDAVTASRVIIT 62
Query: 367 ILTSNKVVLDVYLG---KDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 537
+ S+ V +++G G+V + + GS LI +ST+DP I + K D P
Sbjct: 63 SVMSDDVPA-LHIGTTETPGIVHYLQPGSTLIVTSTLDPRKITAIQAVMPTK-THLLDVP 120
Query: 538 VSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNN 702
+ GGV A A L +A G K+ P+L G ++ G+ G+G KL N
Sbjct: 121 MIGGVKYAREAGLVLIAAGDKQAVADVTPILKTFGTVKY-VGEQGNGAKLKLITN 174
>UniRef50_A0JRK4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=3; Actinomycetales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Arthrobacter sp. (strain FB24)
Length = 299
Score = 67.7 bits (158), Expect = 3e-10
Identities = 53/186 (28%), Positives = 84/186 (45%), Gaps = 2/186 (1%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ LGLG MG MA L + TV G+D ++ L A + G+ S
Sbjct: 7 ITVLGLGAMGLPMATRLASQ-LTVHGFDIAEPRLKLAEEAGIRTFASAREASEGADALLL 65
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPN-VPKQIFPIALEKGLGFTDAPVS 543
+ + + + DV G +GV + K G+++I ST+ + +P + +A E G+ DAP+S
Sbjct: 66 AVRNGEQLNDVLFGANGVASVLKPGAVVILGSTVGTDAIPATVDRLA-EYGVELVDAPLS 124
Query: 544 GGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCG-QIGSGXVAKLTNNXLMGXP 720
GG A L + G E E++ P L ++ + G + G G K N L G
Sbjct: 125 GGPKRAGEGDLLIVVGASPEAQEKARPALELLASTLTVVGDKPGDGQALKTVNQLLCGVH 184
Query: 721 RLAXAD 738
A A+
Sbjct: 185 IAAAAE 190
>UniRef50_A0RU56 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Cenarchaeum symbiosum|Rep: 3-hydroxyisobutyrate
dehydrogenase - Cenarchaeum symbiosum
Length = 282
Score = 67.7 bits (158), Expect = 3e-10
Identities = 46/164 (28%), Positives = 66/164 (40%)
Frame = +1
Query: 211 MGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSILTSNKVV 390
+G + L+K G V Y+ + D A G A S + +T +
Sbjct: 2 LGTGIGLRLLKTGINVIAYNRTADKTKALEDAGARIAKSPGEAAGLSDTVITCVTDADAL 61
Query: 391 LDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAXNA 570
V G++G+ A K +L D STI+P I + G+ DAPV GG A
Sbjct: 62 EQVSFGENGIAQGAHKDLVLCDMSTINPEGAVSISKKLADAGIRMVDAPVMGGPGAAMRG 121
Query: 571 TLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNN 702
L MA G K +E +L + K F+ G G+ KL N
Sbjct: 122 ELVIMASGDKGAYEERRGILGAVSRKMFYLGGSGTAYSIKLAMN 165
>UniRef50_Q7NEW9 Cluster: Glr3759 protein; n=3; Bacteria|Rep:
Glr3759 protein - Gloeobacter violaceus
Length = 290
Score = 67.3 bits (157), Expect = 5e-10
Identities = 49/176 (27%), Positives = 77/176 (43%), Gaps = 1/176 (0%)
Frame = +1
Query: 190 AFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSI 369
A LG+G MG MAA L+K G V ++ + A+ G A + +
Sbjct: 5 AVLGMGAMGSRMAAALLKAGHQVTVWNRNSQKTAPLAEMGAKAAQTPRAAVEEVDFAVCM 64
Query: 370 LTSNKVVLDVYLG-KDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+ + V+L + G +A ++ I+SST+ +++ +G DAPVSG
Sbjct: 65 VRDDAASRFVWLDFETGALAGLPADAVAIESSTLSVAGVQELAEHFQARGKTLLDAPVSG 124
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMG 714
A L F+ GG ++ P+L MG H G +G+G KL N L+G
Sbjct: 125 SRPQAEAGQLIFLVGGDAGAVAKAGPILNAMGGTVHHAGPLGNGAAVKLAINALLG 180
>UniRef50_Q0BTJ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Granulibacter bethesdensis CGDNIH1|Rep:
2-hydroxy-3-oxopropionate reductase - Granulobacter
bethesdensis (strain ATCC BAA-1260 / CGDNIH1)
Length = 293
Score = 67.3 bits (157), Expect = 5e-10
Identities = 55/176 (31%), Positives = 80/176 (45%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+A LG G MG +MA L G V ++ + AA+ G+ A S
Sbjct: 9 IAVLGTGIMGRWMACRLADAGHEVTVWNRNPVR---AAELGLPVATSAPDAAHGADVAL- 64
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
++ S+ D L V A+ G++L+ SS Q ++ + DAPVSG
Sbjct: 65 LMVSDGPACDAVLETGFVDTMAQNGTVLVMSSIEPWRARAQAKKVSPRF---YVDAPVSG 121
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMG 714
G GA N TLA MAGG + R P+ +G + G IG+G +AKL N ++G
Sbjct: 122 GEGGARNGTLAIMAGGEEAVLNRLAPVFAALG-RMTRIGDIGAGQLAKLANQLIVG 176
>UniRef50_A0YMN9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
Cyanobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Lyngbya sp. PCC 8106
Length = 371
Score = 67.3 bits (157), Expect = 5e-10
Identities = 48/176 (27%), Positives = 75/176 (42%), Gaps = 4/176 (2%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ +G GN+G AAN + G++V YD + + G +S +
Sbjct: 19 LGIIGCGNIGKRQAANFLAHGYSVYVYDINPARMAQLQSLGAHITHSCAELATHCEVIFT 78
Query: 367 IL-TSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV- 540
L T + + V G+ + + GS+ ID +T P ++ G+ D P
Sbjct: 79 ALPTPSDTIKAVLEGEQNLSQGLRSGSIYIDITTNSPETIHRLHQAISPLGVEMLDVPFN 138
Query: 541 --SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNN 702
S G LA +A G + FER PLL +M + +CG+IGSG KL +N
Sbjct: 139 DCSEGATSEGGMGLAVLASGSRATFERVEPLLQLMADQVLYCGEIGSGTRCKLIHN 194
>UniRef50_Q120Q9 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=7; Burkholderiales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 297
Score = 66.9 bits (156), Expect = 6e-10
Identities = 48/175 (27%), Positives = 74/175 (42%), Gaps = 1/175 (0%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYD-PSKDALNAAAKNGVTPANSIXXXXXXXXX 357
K + +G+G MG +A+N++K G+ + + P L G T +S
Sbjct: 2 KKIGMVGIGMMGHGIASNIIKHGYPMVLLEHPGNQPLQGLIAAGATTTDSAATLAGVVDI 61
Query: 358 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 537
+T V DV K G++ K G+++ID ST P+ +I + G F DAP
Sbjct: 62 IILCVTGTPEVEDVLYRKGGLLEGIKPGTIVIDCSTAIPSSTIRIAESVEKAGGRFLDAP 121
Query: 538 VSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNN 702
++ A L + GG FE P+L G +GSG KL +N
Sbjct: 122 MTRTPKEAAEGRLNLIVGGDPALFESCKPVLECYAENIVLAGPVGSGHRLKLLHN 176
>UniRef50_Q9RX16 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=6;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Deinococcus radiodurans
Length = 310
Score = 66.1 bits (154), Expect = 1e-09
Identities = 50/174 (28%), Positives = 76/174 (43%)
Frame = +1
Query: 190 AFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSI 369
AFLGLG MG MAA+L + + G + A A++ A S +
Sbjct: 21 AFLGLGAMGFPMAAHLAAQAASGGGRALVWNRTEAKAQDHAARAGSEAVSLADTAQADVL 80
Query: 370 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 549
T +V + H + G++ +D ++ P+ ++ G+ F DAPVSGG
Sbjct: 81 FTCLPTSAEVDEIIAALSPHLRPGTVWVDCTSGHPDAARRQRETLDALGVKFLDAPVSGG 140
Query: 550 VMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLM 711
GA TL M GG ++ + + P L G K G+ G+G K NN L+
Sbjct: 141 TSGAEAGTLTVMLGGPADEIDAASPHLAFAG-KVVRVGETGAGFAVKAVNNMLL 193
>UniRef50_Q21ZN3 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Rhodoferax ferrireducens T118|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Rhodoferax ferrireducens (strain DSM 15236 / ATCC
BAA-621 / T118)
Length = 292
Score = 66.1 bits (154), Expect = 1e-09
Identities = 49/180 (27%), Positives = 75/180 (41%), Gaps = 2/180 (1%)
Frame = +1
Query: 169 SNTDKNVAFLGLGNMGGFMAANLVKKGF--TVRGYDPSKDALNAAAKNGVTPANSIXXXX 342
SNT + +GLG MG + NL+K GF TV G + ++ +++ G + S+
Sbjct: 3 SNTSLRIGLIGLGLMGHGIGRNLLKNGFALTVMG-NVNRAPVDSLVSLGANESKSVAELV 61
Query: 343 XXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLG 522
+T + V + G++ + G ++ID ST P+ I LE G
Sbjct: 62 DASDVVMLCVTGSPQVESLMNRDQGILQSIRPGQIVIDCSTSQPSSSAIINAALLEAGAL 121
Query: 523 FTDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNN 702
F DAP+ A L M G + E P+L H G++ S KL NN
Sbjct: 122 FVDAPLGRTPAEAEAGKLNVMVGATPQLLEHIRPVLQAFCENIIHVGEVISAQKLKLINN 181
>UniRef50_A3Y8R5 Cluster: Putative dehydrogenase; n=1; Marinomonas
sp. MED121|Rep: Putative dehydrogenase - Marinomonas sp.
MED121
Length = 297
Score = 66.1 bits (154), Expect = 1e-09
Identities = 46/173 (26%), Positives = 82/173 (47%), Gaps = 4/173 (2%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVK----KGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXX 354
+ F+GLGNMG MAANL++ + D +++ ++ G A+S+
Sbjct: 3 IGFIGLGNMGSGMAANLLEYCKANHNELLVLDLNQEVVSQFVDKGARKADSVKHVAQECD 62
Query: 355 XXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 534
+ L S+ V + G++G++ +A+ G+ ++ST + + +++ IA L DA
Sbjct: 63 VIFTSLPSSVQVNHIAFGEEGILENAQAGATWFETSTNELSEWEKVKAIA-PSHLSLIDA 121
Query: 535 PVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKL 693
PV+GG GA TL + G ++ + +L G G+G V KL
Sbjct: 122 PVTGGAEGAAAGTLTMLLGIDEQILTKFTSMLNAFTKNAIRMGPSGAGYVTKL 174
>UniRef50_Q8F4I7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4;
Leptospira|Rep: 3-hydroxyisobutyrate dehydrogenase -
Leptospira interrogans
Length = 296
Score = 65.7 bits (153), Expect = 1e-09
Identities = 46/174 (26%), Positives = 78/174 (44%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
++ +G G MG MA NL K G ++R Y + + K+ V +S
Sbjct: 7 ISIIGTGIMGRGMAVNLAKAGHSLRLYTRNLSKIQDLKKDNVQIFDSPIEAAKNSDLVVL 66
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
LT +++V + G++ K +LID T ++ ++ + EK + F D+P++G
Sbjct: 67 CLTEDQIVEKETISS-GLLD--TKPPILIDCGTTSLSLTLKLSKLCSEKKIRFYDSPMTG 123
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXL 708
A + + FM G ++ D + V G +CG IG G AKL N +
Sbjct: 124 SKNAARDGQILFMIGAKQVDIKDIQFFFEVCGKNAVYCGSIGGGQKAKLALNMI 177
>UniRef50_Q9I1R8 Cluster: Probable dehydrogenase; n=7; Pseudomonas
aeruginosa|Rep: Probable dehydrogenase - Pseudomonas
aeruginosa
Length = 291
Score = 65.3 bits (152), Expect = 2e-09
Identities = 50/176 (28%), Positives = 78/176 (44%), Gaps = 1/176 (0%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
V FLGLG MG MA LV+ G V ++ S A G A + S
Sbjct: 3 VGFLGLGGMGAAMATRLVQAGLEVTVWNRSAAACEPLVALGAARAEEVGELFGLDVVI-S 61
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+L ++ + V L G + A+ G + + ST+ + + + +GL F APV G
Sbjct: 62 MLADDQAIRGVLLDS-GALERARPGLIHLSMSTLSLDCVEALDQAHQRQGLAFVAAPVFG 120
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVA-KLTNNXLM 711
A L + GG +E E+ LL +MG K + G+ G +A K++ N ++
Sbjct: 121 RTDVAEAGKLNIVVGGPEEAIEQVKALLEIMGQKTWFFGKDPRGAMAVKISGNFMI 176
>UniRef50_A0GI22 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia phytofirmans PsJN|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Burkholderia phytofirmans PsJN
Length = 355
Score = 65.3 bits (152), Expect = 2e-09
Identities = 33/74 (44%), Positives = 42/74 (56%)
Frame = +1
Query: 517 LGFTDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLT 696
+G+ DAPVSGGV GA TLA MAGG D E PLL ++ H G +G+G AKL
Sbjct: 175 IGWIDAPVSGGVAGATAGTLAVMAGGAAADVEAVKPLLGAYASRVTHMGDVGAGQTAKLC 234
Query: 697 NNXLMGXPRLAXAD 738
N ++ A A+
Sbjct: 235 NQTIVTATLAAIAE 248
>UniRef50_Q0C8I2 Cluster: Predicted protein; n=3;
Pezizomycotina|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 320
Score = 64.9 bits (151), Expect = 2e-09
Identities = 64/209 (30%), Positives = 90/209 (43%), Gaps = 13/209 (6%)
Frame = +1
Query: 166 SSNTDKNVAFLGLGNMGGFMAANLVKK---GFTVRGYDPSKDALN---AAAKNGVTPANS 327
SS + ++ F+GLG MG MA L+ + +D + A+N A + S
Sbjct: 2 SSLSSDDIGFIGLGAMGLPMAQQLIANVPAPTRLYVFDIADQAMNDFVAMYPHKAVAGKS 61
Query: 328 IXXXXXXXXXXXSILTSNKVVLDVYLGKD-GVVAHAKKGSLLIDSSTIDP--NVPKQIFP 498
+++ V VYL + GV + LLID STID ++ +
Sbjct: 62 PRDVAEHSKTIITMVPEGSHVRAVYLDESTGVCSTPLDTRLLIDCSTIDTATSLAVKAHI 121
Query: 499 IALEKGLGFTDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPL----LXVMGAKQFHCGQ 666
F DAPVSGGV+GA +AF G K D +LPL L +MG + CG
Sbjct: 122 TTHHASASFYDAPVSGGVLGAQKGAIAFFLGCAKTD--PNLPLLTDTLRLMGKEVIPCGG 179
Query: 667 IGSGXVAKLTNNXLMGXPRLAXADCXXHG 753
G AKL NN L G +A ++ G
Sbjct: 180 PSLGLSAKLCNNYLSGLIAIANSEALNIG 208
>UniRef50_A6RMW8 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 446
Score = 64.9 bits (151), Expect = 2e-09
Identities = 58/192 (30%), Positives = 92/192 (47%), Gaps = 10/192 (5%)
Frame = +1
Query: 169 SNTDKN-VAFLGLGNMGGFMAANLVKKGFTVRGYD---PSKDALNAAAKNGVTPANSIXX 336
S++DK VAF+GLG MG MA NL+K F+V G+D P+ + +A N T S
Sbjct: 2 SSSDKPAVAFIGLGAMGMGMATNLLKT-FSVTGFDVYEPTLEKFRSAGGNTATTPRSAVA 60
Query: 337 XXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDP-NVP--KQIFPIAL 507
+ T+ + + ++ G + + + +I SST P +VP +++
Sbjct: 61 NAQYIVIM--VATAAQTLAVLFDDVTGAIHELQPNATIILSSTAFPEHVPEVRELLDNKY 118
Query: 508 E-KGLGFTDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHC--GQIGSG 678
K + DAPVSGG A TL +A G ++ + + P+L M A H G +G+G
Sbjct: 119 NRKDVELVDAPVSGGTSRAALGTLVILASGPEKSLDAAKPVLDAM-ADPLHMIPGGLGAG 177
Query: 679 XVAKLTNNXLMG 714
K+ + L G
Sbjct: 178 TKVKMVHQALAG 189
>UniRef50_A6R0U9 Cluster: Predicted protein; n=1; Ajellomyces
capsulatus NAm1|Rep: Predicted protein - Ajellomyces
capsulatus NAm1
Length = 444
Score = 64.9 bits (151), Expect = 2e-09
Identities = 57/197 (28%), Positives = 87/197 (44%), Gaps = 9/197 (4%)
Frame = +1
Query: 175 TDK-NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSI-XXXXXX 348
T+K ++ F+GLG MG MA NL+K G+ V+GYD + + G A+S
Sbjct: 3 TEKPSIGFVGLGLMGFGMATNLIKLGYVVKGYDIQETTMARFKDAGGQIASSPGGAAGGN 62
Query: 349 XXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTID----PNVPKQIFPIALEKG 516
+ T+ + + ++ ++G+ G+ LI ST+ + Q+ I E
Sbjct: 63 MFCVCMVATAAQAQVAIFDHENGIAKGLPSGATLILCSTVSAVSAQSYRDQLVSIGRE-D 121
Query: 517 LGFTDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQ---FHCGQIGSGXVA 687
+ F DAPVSGG A TL MAGG E LL M F G +G+G
Sbjct: 122 VYFIDAPVSGGARKAGEGTLTIMAGGSDAALEEGKFLLTEMADTNKLYFVPGGVGAGSNM 181
Query: 688 KLTNNXLMGXPRLAXAD 738
K+ + LA ++
Sbjct: 182 KMIHQVFAAIHILAASE 198
>UniRef50_A7DWL2 Cluster: Putative dehydrogenase; n=1; Streptomyces
tendae|Rep: Putative dehydrogenase - Streptomyces tendae
Length = 293
Score = 64.5 bits (150), Expect = 3e-09
Identities = 48/184 (26%), Positives = 75/184 (40%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
VA +GLG MG MA L++ GF V ++ S AA+ G A S
Sbjct: 5 VAVIGLGGMGSGMALALLRAGFQVTVFNRSPQKAEQAARAGAAVAPSAGAAGAAARVVLL 64
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
L V +V G+ VV + G++L+D++T+ P+ + G+ +A V G
Sbjct: 65 SLADEPAVDEVLFGE--VVWQLQPGTVLVDTTTVSPSFARNTAVRLAASGVERLEACVMG 122
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPRL 726
A + L G + + +L +G + H G G KL N L+G
Sbjct: 123 NPEMAESGRLRIFTSGSHSAVDAAGDVLSALGQEVRHLGDAGRASALKLALNLLLGIQTA 182
Query: 727 AXAD 738
A+
Sbjct: 183 GLAE 186
>UniRef50_A5P600 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Methylobacterium sp. 4-46|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Methylobacterium sp. 4-46
Length = 290
Score = 64.5 bits (150), Expect = 3e-09
Identities = 52/179 (29%), Positives = 79/179 (44%), Gaps = 3/179 (1%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ ++GLG +G MA +LV G V +D +D AA G A+ +
Sbjct: 3 IGWIGLGKLGAPMARHLVAAGHAVLAFD--RDPGRLAAVPGAEAAD--LPGVAACGVVVT 58
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
L + + V LG +G++A +L+++ST+ P + A G+ + APVSG
Sbjct: 59 SLPDDAALAAVALGPEGLLARMAPDGVLVETSTVSPETSAALREAAEAGGILYLAAPVSG 118
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVA---KLTNNXLMG 714
A ATL G + ER+ PLL A+ H +G G A KL N +G
Sbjct: 119 STATAEAATLTLFCSGPETALERARPLLATF-ARTIHA--VGPGEEARFLKLAINHFVG 174
>UniRef50_Q6F842 Cluster: Putative 3-hydroxyisobutyrate
dehydrogenase or 2-hydroxy-3- oxopropionate reductase;
n=2; Acinetobacter|Rep: Putative 3-hydroxyisobutyrate
dehydrogenase or 2-hydroxy-3- oxopropionate reductase -
Acinetobacter sp. (strain ADP1)
Length = 291
Score = 64.1 bits (149), Expect = 4e-09
Identities = 44/175 (25%), Positives = 78/175 (44%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+AF+G+G MG MA LV+ GF+V ++ ++ A + G +
Sbjct: 9 IAFIGMGLMGSRMATRLVQAGFSVAVWNRTQSACDVLLDMGAQALS--LEKIADYPVILM 66
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
L ++ V VY + V + +++D S++ N K + A ++ + D+PVSG
Sbjct: 67 CLADDQAVNHVY---EQVHHLVRPQQIIVDFSSLSVNQTKYLADRAQQQQAIWIDSPVSG 123
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLM 711
G GA TL AGG + + + V+ + G G+G K+ N ++
Sbjct: 124 GTSGAEQGTLVIFAGGNESTIQDLGLIYNVLSQRVTRMGDTGTGQATKICNQLIV 178
>UniRef50_Q1V2K7 Cluster: NADP oxidoreductase, coenzyme
F420-dependent:6- phosphogluconatedehydrogenase,
NAD-binding:3-hydroxyacyl-CoA; n=1; Candidatus
Pelagibacter ubique HTCC1002|Rep: NADP oxidoreductase,
coenzyme F420-dependent:6-
phosphogluconatedehydrogenase,
NAD-binding:3-hydroxyacyl-CoA - Candidatus Pelagibacter
ubique HTCC1002
Length = 284
Score = 64.1 bits (149), Expect = 4e-09
Identities = 44/177 (24%), Positives = 77/177 (43%), Gaps = 1/177 (0%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVK-KGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXX 357
KNV F+G+G MG +A N++K K + ++ + G S
Sbjct: 2 KNVGFIGVGYMGYGIAKNILKNKNNLFVIANKNRSPIEKIVSEGAVEVKSYDELCSKDLD 61
Query: 358 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 537
+ +N + + K ++ +L+ID +T D N + I K + + + P
Sbjct: 62 CLFLCVTNTPIAHSIIEK--ILPLLNSDTLIIDITTHDQNGSIEANKIFKSKNINYIECP 119
Query: 538 VSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXL 708
V GG + A L + GG +E+F+++ L F+ G++G G +KL NN L
Sbjct: 120 VMGGPVQAEEGVLGGIIGGSEENFKKAEVFLKAFCKDYFYFGEVGMGTKSKLLNNFL 176
>UniRef50_Q221W9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Rhodoferax ferrireducens T118|Rep:
2-hydroxy-3-oxopropionate reductase - Rhodoferax
ferrireducens (strain DSM 15236 / ATCC BAA-621 / T118)
Length = 303
Score = 63.7 bits (148), Expect = 6e-09
Identities = 45/184 (24%), Positives = 76/184 (41%), Gaps = 3/184 (1%)
Frame = +1
Query: 169 SNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAK---NGVTPANSIXXX 339
S + V F+G+G MG MA +++ KG V K A +G P +
Sbjct: 5 STSSLKVGFIGVGMMGCGMAKHVLAKGHPVALLIRKKADEERCADLLTHGAQPLKTAAEV 64
Query: 340 XXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGL 519
+T + V +V G G++ K G +++D ST P+ +++ KG
Sbjct: 65 AATADVIIICVTGSPQVEEVVFGDTGILQTLKPGCVVVDCSTSLPDSTRRVAQAIAAKGG 124
Query: 520 GFTDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTN 699
F DA ++G A L + GG E P+ + F+CG + +G KL +
Sbjct: 125 QFLDAAMTGTPKHADEGKLNLLVGGDPEVLTSVRPVFALFAENIFYCGAVSAGHTTKLLH 184
Query: 700 NXLM 711
++
Sbjct: 185 QFVV 188
>UniRef50_Q392H4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=8; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia sp. (strain
383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
/ R18194))
Length = 292
Score = 63.3 bits (147), Expect = 7e-09
Identities = 49/175 (28%), Positives = 75/175 (42%), Gaps = 3/175 (1%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
VA LG+G MG +A NL ++GFTVR ++ ++ +A A +GV + +
Sbjct: 12 VAVLGIGVMGAPIARNLARQGFTVRAWNRTRAKADALAADGVAAFATPAETVSDARVVVT 71
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+L VL + G++ + ST+ ++ A L F DAPV G
Sbjct: 72 VLNDADGVLK---AMEAAAPKLAAGTIWVQVSTVGVRGIARLAAFARTHDLVFYDAPVQG 128
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHC---GQIGSGXVAKLTNN 702
A NA L +A G + D + PL +G + G G+G KL N
Sbjct: 129 SRQPAENAQLVVLAAGPESDRAQVQPLFDAIGRRTLWVADDGSTGAGSRLKLALN 183
>UniRef50_Q2JEN4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Frankia sp. CcI3|Rep:
6-phosphogluconate dehydrogenase, NAD-binding - Frankia
sp. (strain CcI3)
Length = 290
Score = 63.3 bits (147), Expect = 7e-09
Identities = 50/185 (27%), Positives = 77/185 (41%), Gaps = 1/185 (0%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ F+GLG MG MA NL+ G TV ++ S D + A G PA+ S
Sbjct: 3 IGFIGLGGMGSAMARNLIDAGHTVLAWNRSPDPVTELAAAGAVPAS--ISEAFATGIVLS 60
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+L ++ V D L V+ A G+L ++ +T+ + Q E GL + APV G
Sbjct: 61 MLADDQAVTDRLL-DPRVLTAAPAGALHVNMATVSTALAIQARREHAEHGLRYLAAPVFG 119
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGS-GXVAKLTNNXLMGXPR 723
A L + G + PL V+G + + G + K+ N L+
Sbjct: 120 RTDAARAGNLTIVTSGDPDTIAEVQPLFDVLGRRTWTVGDAPEHANLVKILGNYLIACSI 179
Query: 724 LAXAD 738
A A+
Sbjct: 180 EAMAE 184
>UniRef50_A0AWL7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=1; Arthrobacter sp. FB24|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Arthrobacter sp. (strain FB24)
Length = 297
Score = 63.3 bits (147), Expect = 7e-09
Identities = 51/188 (27%), Positives = 84/188 (44%), Gaps = 3/188 (1%)
Frame = +1
Query: 184 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 363
+V +GLG MG +AA+L+ +V +D D + A G P+ S
Sbjct: 5 HVGVVGLGGMGKALAASLIAADHSVAVWDRHTDRVATTAMIGAAPSVSPRQLAEQSHVIF 64
Query: 364 SILTSNKVVLDVYLGKD-GVVAHAKKGSLLIDSSTIDPNVPKQIFP--IALEKGLGFTDA 534
L + V +V ++ GV+A + G+L++D +T DP + + + AL G + DA
Sbjct: 65 LALPNPTAVREVLYDEEAGVLAGLRAGALIVDMTTGDPELAQDVAQRVAALGNGARYVDA 124
Query: 535 PVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMG 714
PVSG A N T+ M GG + ++ + + G +G G KL + +
Sbjct: 125 PVSG---TAPNLTV--MIGGEAGVLGGAESIVQDVAGTLLYAGALGDGFATKLVHQHVKY 179
Query: 715 XPRLAXAD 738
LA A+
Sbjct: 180 ATHLAVAE 187
>UniRef50_Q82ZC2 Cluster: 6-phosphogluconate dehydrogenase family
protein; n=16; Bacteria|Rep: 6-phosphogluconate
dehydrogenase family protein - Enterococcus faecalis
(Streptococcus faecalis)
Length = 299
Score = 62.9 bits (146), Expect = 1e-08
Identities = 44/177 (24%), Positives = 78/177 (44%), Gaps = 2/177 (1%)
Frame = +1
Query: 184 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 363
++ F+GLG MG MA N+ ++G+ + G+D +K+A A + G++ +S+
Sbjct: 2 DIGFIGLGKMGLNMALNVHEQGWPIIGFDVTKEARATAREQGLSVVDSLSELLKALNKRK 61
Query: 364 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 543
I S +V +++DS + + +A EKG+ F D S
Sbjct: 62 VIFLSTPAGQITNQLVAELVEQLAPEDIIVDSGNSNFHDSVANAQLAKEKGIYFIDCGTS 121
Query: 544 GGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQ--FHCGQIGSGXVAKLTNNXL 708
GG+ GA M GG E + P + +Q + G+ G+G K+ +N +
Sbjct: 122 GGIKGAREGA-CLMVGGAPEAVKVLTPFFEDLACEQGYLYAGKSGAGHYLKMVHNGI 177
>UniRef50_A1UDJ6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=7; Mycobacterium|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Mycobacterium sp. (strain KMS)
Length = 292
Score = 62.9 bits (146), Expect = 1e-08
Identities = 54/187 (28%), Positives = 76/187 (40%), Gaps = 1/187 (0%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
+ V +GLG MG +AA+L+ V +D D L + G A
Sbjct: 2 RRVGVIGLGGMGSALAASLLATDHYVVCFDIRPDVLRPIVELGAEAAADARELAGACDVV 61
Query: 361 XSILTSNKVVLDVYLGKD-GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 537
+ L VL+V LG + GV+A G+ L+D ST +P V I G F D P
Sbjct: 62 LTFLPGPSQVLEVALGSERGVLAGLADGAALLDMSTCNPEVAAIIGQAYDAAGRRFVDCP 121
Query: 538 VSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGX 717
VS A N T+ + GG +L + +CG G+G KL N +
Sbjct: 122 VS---RKAPNMTV--LVGGPSGVLGPDADVLAAVSRTLVYCGHRGAGYATKLLNQHIKYS 176
Query: 718 PRLAXAD 738
LA A+
Sbjct: 177 WYLASAE 183
>UniRef50_Q21ZT0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Rhodoferax ferrireducens T118|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Rhodoferax ferrireducens (strain DSM 15236 / ATCC
BAA-621 / T118)
Length = 315
Score = 62.1 bits (144), Expect = 2e-08
Identities = 46/178 (25%), Positives = 79/178 (44%), Gaps = 2/178 (1%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYD-PSKDALNAAAKNGV-TPANSIXXXXXXXX 354
+ + F+G+G MG +A NL+K+G + D P ++ K G T A
Sbjct: 5 RKLGFIGVGLMGHGLAKNLLKQGHAMTLLDHPGNQPIDDLMKMGAQTVATPKEVATAADV 64
Query: 355 XXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 534
+ S +V VY G DG++ + G +++D++T DP ++ +G + DA
Sbjct: 65 VFLCVNGSPQVEACVY-GADGLLEGLRAGGVVVDATTADPVSTLKVAAAVQARGGRYVDA 123
Query: 535 PVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXL 708
P++ A + + M GG PL+ F G++GSG KL +N +
Sbjct: 124 PMTRTSQHAEDGCVNAMLGGDAVTIAEVRPLIEAYAENIFIGGEVGSGHRLKLLHNYI 181
>UniRef50_A1SQ87 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Nocardioides sp. (strain
BAA-499 / JS614)
Length = 318
Score = 62.1 bits (144), Expect = 2e-08
Identities = 44/177 (24%), Positives = 83/177 (46%), Gaps = 1/177 (0%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
V ++G G MG MA+ L + G V ++ ++ A ++ G A++I
Sbjct: 13 VGWIGAGRMGAAMASRLARAGEDVTVWNRTRAKAEALSEVGCGVADTIADLRGHDVVFTM 72
Query: 367 ILTSNKVVLDVYLGKDGVVAH-AKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 543
+ T + V +G+ G++A A+ ++++D ST+ + E+G+ F APVS
Sbjct: 73 VSTPADLE-QVLVGEGGLLADPARVPAVVVDCSTVSTESSAAMRAACSERGVAFLAAPVS 131
Query: 544 GGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMG 714
G L+ + G +E +ER LL +G + G+ +AK+ +N ++G
Sbjct: 132 GNGKVVRAGGLSLVVSGPEETYERVAHLLDHLGKGATYVGEGELARLAKICHNVMLG 188
>UniRef50_Q5GUM4 Cluster: Dehydrogenase; n=5;
Gammaproteobacteria|Rep: Dehydrogenase - Xanthomonas
oryzae pv. oryzae
Length = 335
Score = 60.9 bits (141), Expect = 4e-08
Identities = 48/173 (27%), Positives = 74/173 (42%), Gaps = 1/173 (0%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ FLGLG MG MA NL++ GF + ++ S + G T S
Sbjct: 46 IGFLGLGTMGLPMAHNLLRGGFELSVWNRSPERAQPLRDAGATVVEQ-PCGAAHGPLLFS 104
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+L + V L + GV+ GS+ ++ +TI + + + E+G+ + APV G
Sbjct: 105 MLADDDAVRQTLLER-GVLDALPAGSVHVNMATISVALAHALTALHAERGVAYVAAPVLG 163
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQI-GSGXVAKLTNN 702
V A L +AGG R P+ +G K +H G+ AKL N
Sbjct: 164 RVDVAEAGKLNILAGGDDVAVARVQPMFDALGQKTWHIGRAPEQANAAKLAAN 216
>UniRef50_A3ES45 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Leptospirillum sp. Group II UBA|Rep:
3-hydroxyisobutyrate dehydrogenase - Leptospirillum sp.
Group II UBA
Length = 307
Score = 60.5 bits (140), Expect = 5e-08
Identities = 40/162 (24%), Positives = 69/162 (42%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
K ++G GNMG MA NL++ G + ++ + L K G +
Sbjct: 12 KEAVWIGTGNMGLPMAKNLLRSGIRLGVHNRTPQRLAPLLKAGAHAIADLRGSLSGTPLV 71
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 540
++L + V + L + G++ +G + + T+ P ++ E+G APV
Sbjct: 72 FTMLADDAAVKETVLKEGGLLDSLPQGGVHVSMGTLSPGFVLELSKTHTERGQILVSAPV 131
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQ 666
G A TL +A G ++ E LPLL +G+ F G+
Sbjct: 132 FGRPDRAEAGTLTIVAAGPQKTLESLLPLLEHLGSPVFCVGE 173
>UniRef50_Q7Q161 Cluster: ENSANGP00000013149; n=11; Culicidae|Rep:
ENSANGP00000013149 - Anopheles gambiae str. PEST
Length = 581
Score = 60.5 bits (140), Expect = 5e-08
Identities = 41/174 (23%), Positives = 70/174 (40%)
Frame = +1
Query: 193 FLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSIL 372
FLGLG MG + NL+K G +V ++ S + G A++ S +
Sbjct: 300 FLGLGVMGCGIVKNLIKSGHSVVVWNRSAHKCRKFQEVGAEVADTPSDVVEMTDVTYSCV 359
Query: 373 TSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGV 552
+ +V D+ G GV++ G ++ + +DP I + KG + +A + G
Sbjct: 360 SDPQVAKDMVFGNCGVMSANLAGKGYVEMTGVDPETSNDINEAIISKGGRYLEAQIQGSK 419
Query: 553 MGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMG 714
A TL +A G + FE + F+ G +G+ L + G
Sbjct: 420 NQAEEGTLIILASGDRLLFEECQSCFEAISRNSFYLGDVGNATKMNLILQMISG 473
>UniRef50_Q6RXW5 Cluster: Succinic semialdehyde dehydrogenase; n=2;
Rhodococcus|Rep: Succinic semialdehyde dehydrogenase -
Rhodococcus sp. TK6
Length = 262
Score = 60.1 bits (139), Expect = 7e-08
Identities = 48/172 (27%), Positives = 80/172 (46%), Gaps = 1/172 (0%)
Frame = +1
Query: 196 LGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSILT 375
+GLG +GG + A+L + G V GYD +++ L ++ +PA S S+
Sbjct: 5 IGLGPIGGKIGAHLAELGRKVYGYDFNQERLREWSEETASPAGS-DLAAVDWPSIDSVHV 63
Query: 376 SNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVM 555
+ ++ V + + AH + + +T+ P ++I P A G +APVSGG
Sbjct: 64 AVRLADQVSSVFEALAAHTAQPLTVFVHTTLAPADARKILPSA-PAGWRVFEAPVSGGPQ 122
Query: 556 GAXNATL-AFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXL 708
GA + ++ F+AG D E + LL + + F G + KL NN L
Sbjct: 123 GARHGSMTVFLAGPAPTDAENA--LLEDISGRVFQMESYGQPALVKLLNNAL 172
>UniRef50_A0K107 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Arthrobacter sp. FB24|Rep: 2-hydroxy-3-oxopropionate
reductase - Arthrobacter sp. (strain FB24)
Length = 302
Score = 59.7 bits (138), Expect = 9e-08
Identities = 51/192 (26%), Positives = 82/192 (42%), Gaps = 7/192 (3%)
Frame = +1
Query: 184 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGV--TPANSIXXXXXXXXX 357
+VA +G G MG +A N++ + ++ + + A V TPA +
Sbjct: 17 SVALIGTGPMGAPIARNILAGHVPLTLWNRTAEKARAIGGGTVVATPAAAASEVVL---- 72
Query: 358 XXSILTSNKVVLDVYLGKDGVVAHAKKGSL----LIDSSTIDPNVPKQIFPIALEK-GLG 522
++L V + G+DG++A K + L+ T+ P + L GL
Sbjct: 73 --TVLPDLPQVAALLPGEDGLLAGWKAAGIEHPVLVIHGTVSPVAVAEFADDCLRNWGLT 130
Query: 523 FTDAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNN 702
DAP+SGG +GA L+ M GG E ER PL + + H G+ G+G K N
Sbjct: 131 VVDAPLSGGTIGAEEGRLSIMVGGPAEAVERLTPLFGLYSSTAVHFGKTGAGSTVKACNQ 190
Query: 703 XLMGXPRLAXAD 738
++ A A+
Sbjct: 191 IVVAATVNALAE 202
>UniRef50_Q3W031 Cluster: Putative dehydrogenase; n=1; Frankia sp.
EAN1pec|Rep: Putative dehydrogenase - Frankia sp.
EAN1pec
Length = 285
Score = 58.8 bits (136), Expect = 2e-07
Identities = 48/191 (25%), Positives = 76/191 (39%), Gaps = 2/191 (1%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
VAFLGLG MG MA +++ G + ++ + G + A
Sbjct: 3 VAFLGLGRMGVRMAHHILAAGHELAVWNRTPGRAGELTARGASEAADPAGAVRGADACVL 62
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+L DV V+ A G L+I+ +T+ P ++ +AL GL + DAPV G
Sbjct: 63 MLFDPASAADVLA---AVIPAAPPGLLVINCTTVGPAAAREQGSVALAAGLRYLDAPVIG 119
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMG--AKQFHCGQIGSGXVAKLTNNXLMGXP 720
+ A TL + G D + +L G + H G +G+ K N +
Sbjct: 120 TIGPAEAGTLRVLVGAADADLAAARGILETFGDPGRIDHVGPVGAASALKTVFNLGLAEA 179
Query: 721 RLAXADCXXHG 753
A A+ +G
Sbjct: 180 TAAAAEVLRYG 190
>UniRef50_A3ET09 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Leptospirillum sp. Group II UBA
Length = 311
Score = 58.8 bits (136), Expect = 2e-07
Identities = 40/174 (22%), Positives = 77/174 (44%), Gaps = 2/174 (1%)
Frame = +1
Query: 196 LGLGNMGGFMAANLVKKGFTVRG-YDPSKDALNAAA-KNGVTPANSIXXXXXXXXXXXSI 369
+G+G MG MA L G+ V YD +A A + G + A ++ ++
Sbjct: 14 VGVGRMGSNMALRLNDVGYRVASVYDVRLEAARRVADETGASVARTLAEVTAQSDVIITV 73
Query: 370 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 549
+ +++ + ++ + G + ++ +T+ P++ ++ + ++G +A ++
Sbjct: 74 VGTDREMDALFAETGDSLLVGASGRVFVNCATLSPDIHVEVERRSNDRGADCLEASMASS 133
Query: 550 VMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLM 711
+ A TL M GG+KE FER P+L M A G G K N +M
Sbjct: 134 ITQAREGTLYLMVGGKKEAFERVRPVLEAMSASLRWIGPAGQAAKIKALVNMVM 187
>UniRef50_Q0SAG5 Cluster: Phosphogluconate dehydrogenase; n=23;
Actinobacteria (class)|Rep: Phosphogluconate
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 303
Score = 58.4 bits (135), Expect = 2e-07
Identities = 48/180 (26%), Positives = 74/180 (41%), Gaps = 6/180 (3%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ +GLG MG M L G V GYDP D + A+ +
Sbjct: 3 IGLVGLGKMGFNMRERLRAHGHEVVGYDPRPDVTDVAS------LAELARRLESPRVVWV 56
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
++ + K+ D V+ + G L+ID K + +G+G+ D VSG
Sbjct: 57 MVPAGKITQDTVTELSSVL---ETGDLVIDGGNSRYTDDKVHGELLGSRGIGYLDCGVSG 113
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVM---GAKQ---FHCGQIGSGXVAKLTNNXL 708
GV G + M GG D ER+LP+ + G + H G +G+G AK+ +N +
Sbjct: 114 GVWGLEDG-YGMMVGGSDADVERALPIFDALRPEGERADGFVHAGPVGAGHYAKMIHNGI 172
>UniRef50_A4FKN9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
2-hydroxy-3-oxopropionate reductase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 297
Score = 58.4 bits (135), Expect = 2e-07
Identities = 46/179 (25%), Positives = 76/179 (42%), Gaps = 4/179 (2%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
V +GLG MG +A L + G V S+ AAA+ GV + +
Sbjct: 5 VGVIGLGPMGANLALRLAEAGLDVVATSRSQGTREAAAREGVRVVDDVRALAGRLRAASP 64
Query: 367 ---ILTSNKVVLDVYLG-KDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 534
++ S V DG++A + +++D+ST P + + +G DA
Sbjct: 65 KPVVVVSLPSGPQVRAAVVDGLLADGGE-FVVVDTSTCAPADARSLADDLHARGCAVVDA 123
Query: 535 PVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLM 711
PVSGG A +L+ M GG + D + ++ + CG G+G +AK N ++
Sbjct: 124 PVSGGPTAARAGSLSVMVGGTEADVAAADEVIRAFAGRVVVCGGPGAGQIAKACNQLVV 182
>UniRef50_A3Q3U7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mycobacterium sp. (strain
JLS)
Length = 279
Score = 58.4 bits (135), Expect = 2e-07
Identities = 48/174 (27%), Positives = 66/174 (37%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
V FLG G +G M L+ G V Y +DA G A+S+ S
Sbjct: 5 VGFLGAGQLGEPMVERLLGAGHDVLVYARREDARRRLEAKGAALADSVADLAHGSDVLIS 64
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
L S+ + + LG +G +A+AK ++ + S T G DAPVSG
Sbjct: 65 CLFSDAQLRETGLGPNGFIANAKPAAVFV-SHTTGTVATLTALRDHSSSGPVVLDAPVSG 123
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXL 708
TL + GG + P+L G +GS KL NN L
Sbjct: 124 TADDIAAGTLTVLLGGPADAVAAVTPVLAAYADPLVPTGTLGSALALKLINNLL 177
>UniRef50_Q0W2D7 Cluster: Putative 6-phosphogluconate dehydrogenase;
n=1; uncultured methanogenic archaeon RC-I|Rep: Putative
6-phosphogluconate dehydrogenase - Uncultured
methanogenic archaeon RC-I
Length = 310
Score = 58.0 bits (134), Expect = 3e-07
Identities = 50/178 (28%), Positives = 79/178 (44%), Gaps = 4/178 (2%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ +GLG MGG +A V+KG V + SK + A G+ A++
Sbjct: 3 LGIIGLGRMGGSLALQAVEKGVEVVAH--SKHSHPDFATRGIHIADTYEEFARLLRTPRI 60
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLID--SSTIDPNVPKQIFPIALEKGLGFTDAPV 540
I S + + ++ H ++G +L+D +S +V ++ +KG D
Sbjct: 61 IYLSLPAGQIIDQVIESLIPHLERGDVLMDGGNSFFRDSVARE--EALRKKGFRLLDCGT 118
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAK--QFHCGQIGSGXVAKLTNNXL 708
SGGV GA FM GG +E FE + P+L + + G GSG AKL +N +
Sbjct: 119 SGGVDGARTGA-CFMVGGSREGFELAEPVLKKLAVDGGVLYTGSPGSGHYAKLVHNGI 175
>UniRef50_Q01PV6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Solibacter usitatus Ellin6076|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Solibacter usitatus (strain Ellin6076)
Length = 267
Score = 57.2 bits (132), Expect = 5e-07
Identities = 48/179 (26%), Positives = 74/179 (41%)
Frame = +1
Query: 202 LGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSILTSN 381
+G +G +A L G+TV GYD L + G A + L ++
Sbjct: 1 MGLLGSAIADRLSAAGYTVVGYD-----LIPERRRGADSAQEVIGKCQTTFLC---LPTS 52
Query: 382 KVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGA 561
VV V G V A G ++D +T +P + + G+ + DA V G
Sbjct: 53 DVVAQVI----GSVKPAA-GITMVDCTTGEPESMAAMGEKLAKSGVDYLDATVLGSSKVV 107
Query: 562 XNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXPRLAXAD 738
+ MAGGR+E F+ + PL ++ F+ G G+G KL N +G R A+
Sbjct: 108 RSGAAVVMAGGRRESFDAASPLFRTFASRAFYLGPFGAGARMKLVVNLALGLHRAVLAE 166
>UniRef50_Q1GM24 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding; n=3; Rhodobacteraceae|Rep:
6-phosphogluconate dehydrogenase NAD-binding -
Silicibacter sp. (strain TM1040)
Length = 292
Score = 56.8 bits (131), Expect = 6e-07
Identities = 41/175 (23%), Positives = 71/175 (40%), Gaps = 2/175 (1%)
Frame = +1
Query: 184 NVAFLGLGNMGGFMAANLVKKG-FTVRGYD-PSKDALNAAAKNGVTPANSIXXXXXXXXX 357
+V +G+G MG +A N++ +G F + D P ++ G +
Sbjct: 2 HVGIIGVGLMGHGIARNVLSRGGFALSFLDHPGNQPVDEIVSLGAVACATPAEVAAMSDV 61
Query: 358 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 537
+T + V + G GV ++ ++++D ST P ++ I G + DAP
Sbjct: 62 VILCVTGSPQVEAIVAGDQGVATALRQNAVIVDCSTALPESTLRMAEIVRAAGGDYLDAP 121
Query: 538 VSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNN 702
++ A TL + GG + ER P+L H G + G KL +N
Sbjct: 122 MTRTARHAHEGTLNLLVGGATDTLERVRPVLSTFTEDVAHVGPLSHGHRLKLLHN 176
>UniRef50_A5CN67 Cluster: Putative beta-hydroxyacid dehydrogenase;
n=1; Clavibacter michiganensis subsp. michiganensis
NCPPB 382|Rep: Putative beta-hydroxyacid dehydrogenase -
Clavibacter michiganensis subsp. michiganensis (strain
NCPPB 382)
Length = 291
Score = 56.8 bits (131), Expect = 6e-07
Identities = 44/173 (25%), Positives = 73/173 (42%), Gaps = 1/173 (0%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ LG G MG M+ ++++ G + ++ S + A G T A S
Sbjct: 1 MTLLGTGVMGSGMSRSILRAGLPLTVWNRSAEKAAPLADAGATVAESAADAVRDADVVVV 60
Query: 367 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 546
+L VL+V V + G++++ SST+ ++I +A E + F DAPV G
Sbjct: 61 MLFDADAVLEVLAE---VAPALRPGAVVLQSSTVGVEGTRRIAALAAEHAVRFVDAPVLG 117
Query: 547 GVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCG-QIGSGXVAKLTNN 702
A L + G ++D + P+L G++ G G G KL N
Sbjct: 118 TRGPAEQGLLVHLVSGSEDDLAVARPVLEATGSRTVVAGSDAGPGSALKLACN 170
>UniRef50_Q97ZE5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4;
Sulfolobaceae|Rep: 3-hydroxyisobutyrate dehydrogenase -
Sulfolobus solfataricus
Length = 289
Score = 56.8 bits (131), Expect = 6e-07
Identities = 51/191 (26%), Positives = 77/191 (40%), Gaps = 2/191 (1%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ +GLG MG +AANL K YD +++ + + K N +
Sbjct: 3 IGLIGLGIMGYRIAANLAKANKLNLVYDRTQEKIESFVKE--YKVNGVQNTKDLVESSDV 60
Query: 367 ILTSNKVVLDVYLGKDGV--VAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 540
I+T ++ D Y K V + KG +LID STI P + + G DAPV
Sbjct: 61 IIT---MLADDYAVKSVVEPLIPLMKGKILIDMSTISPTLSISLAKRIESNGGTMFDAPV 117
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMGXP 720
G + L + GG K+ F+ + + + G G G +KL NN L+
Sbjct: 118 IGTSVFVEQKKLVVLVGGPKDKFDIVNDIAKETASLVVYMGPNGMGLYSKLVNNLLLASY 177
Query: 721 RLAXADCXXHG 753
A A+ G
Sbjct: 178 VAAIAEAYNFG 188
>UniRef50_A4EEN1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Roseobacter sp. CCS2|Rep: 3-hydroxyisobutyrate
dehydrogenase - Roseobacter sp. CCS2
Length = 281
Score = 56.4 bits (130), Expect = 9e-07
Identities = 43/177 (24%), Positives = 71/177 (40%)
Frame = +1
Query: 181 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 360
+ + +GLG MG +A + +G V G+ S + GV A+S+
Sbjct: 2 ERIGVIGLGRMGSAIARRMQAQGHQVTGWTRSGRTVE-----GVEIADSLGTLVAQSNTL 56
Query: 361 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 540
L +++ V + D + G +I++ST+ P + K KG DAP+
Sbjct: 57 ILSLLNDEAVASIL---DSCLEMNLTGKQIIETSTVVPTILKDRIERITAKGATAVDAPI 113
Query: 541 SGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLM 711
SGG GG R+ + + FH G +G+G V K NN ++
Sbjct: 114 SGGPELVLAGACGVFIGGDAAAAARAQTTIAGFSGRIFHVGPLGTGIVMKTINNSMI 170
>UniRef50_A1WEB7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Verminephrobacter eiseniae EF01-2|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Verminephrobacter eiseniae (strain EF01-2)
Length = 293
Score = 56.4 bits (130), Expect = 9e-07
Identities = 50/175 (28%), Positives = 78/175 (44%), Gaps = 3/175 (1%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAA-AKNGVTPANSIXXXXXXXXXXX 363
+A GLGNMG + A + + F + +D + A A G P
Sbjct: 1 MAIYGLGNMG-YPIAERIGRHFPTQVFDLDDTRVEKARALFGAAPMGR-PQDLADTRVVV 58
Query: 364 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 543
L S L V + + H +G+++I+SST++P G+ DA +
Sbjct: 59 LCLPSPASSLSVI---EQIAPHLPQGAVVIESSTVNPEHVHAGQKRLAPFGVDVVDASIL 115
Query: 544 GGV--MGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNN 702
GV M A +ATLA GG+ + RS +L + ++Q H G +G+G AK+ NN
Sbjct: 116 AGVEQMAAGSATLAL--GGKPDAIARSQGVLDAIASRQIHFGALGAGAAAKVINN 168
>UniRef50_Q9RU02 Cluster: 6-phosphogluconate dehydrogenase; n=24;
Bacteria|Rep: 6-phosphogluconate dehydrogenase -
Deinococcus radiodurans
Length = 368
Score = 56.0 bits (129), Expect = 1e-06
Identities = 49/184 (26%), Positives = 72/184 (39%), Gaps = 10/184 (5%)
Frame = +1
Query: 187 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 366
+ +GLG MGG M L G V G+D S++A++ GV A+++
Sbjct: 5 IGMIGLGKMGGNMVIRLKNGGQDVVGFDRSQEAIDHLVSQGVA-ADALTSDMDRFIELLG 63
Query: 367 ILTSNKVVLDVYLGK------DGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFT 528
V + V G+ D + G ++ID + + ++ KGL F
Sbjct: 64 EPGQRAVWVMVPAGQITQSVIDDLAGRLSAGDVIIDGGNSNFHDTQRRGEALAAKGLHFV 123
Query: 529 DAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQ----FHCGQIGSGXVAKLT 696
D SGGV G M GG E ER P L + H G GSG K+
Sbjct: 124 DVGTSGGVWGITEG-YGMMVGGPDEGVERIRPALEALAPAPDRGWGHMGPTGSGHYVKMV 182
Query: 697 NNXL 708
+N +
Sbjct: 183 HNGI 186
>UniRef50_Q89GM2 Cluster: Bll6323 protein; n=6; Proteobacteria|Rep:
Bll6323 protein - Bradyrhizobium japonicum
Length = 300
Score = 56.0 bits (129), Expect = 1e-06
Identities = 42/178 (23%), Positives = 74/178 (41%), Gaps = 2/178 (1%)
Frame = +1
Query: 175 TDKNVAFLGLGNMGGFMAANLVKKG-FTVRGYD-PSKDALNAAAKNGVTPANSIXXXXXX 348
T V +G+G MG +A N++ +G F + D P ++ G T +
Sbjct: 5 TVTRVGIIGVGLMGHGIAKNVLARGRFPLAFLDHPGNQPVDDLVGLGATACKTPADVAEA 64
Query: 349 XXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFT 528
+T + V V G G ++ +KG++++D ST P ++ G F
Sbjct: 65 SDIIILCVTGSPQVEAVLTGDAGALSRLRKGTIIVDCSTALPESTLRMAAAVRAAGGAFL 124
Query: 529 DAPVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNN 702
DAP++ A + L + GG + DF+ + +L + G + G KL +N
Sbjct: 125 DAPMTRTAKHAEDGALNLLVGGDETDFQNACAVLASFTERVERVGPVSFGHRLKLLHN 182
>UniRef50_Q4WXG9 Cluster: 3-hydroxyisobutyrate dehydrogenase,
putative; n=1; Aspergillus fumigatus|Rep:
3-hydroxyisobutyrate dehydrogenase, putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 317
Score = 56.0 bits (129), Expect = 1e-06
Identities = 45/133 (33%), Positives = 61/133 (45%), Gaps = 3/133 (2%)
Frame = +1
Query: 364 SILTSNKVVLDVYLGKD-GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALE--KGLGFTDA 534
+++ + V VYL GV+ + +L+D STID + + K F DA
Sbjct: 84 TMVPEGRHVRSVYLDSHAGVLTTSVDDKILVDCSTIDTATSMDVGAAVCQNSKTAAFYDA 143
Query: 535 PVSGGVMGAXNATLAFMAGGRKEDFERSLPLLXVMGAKQFHCGQIGSGXVAKLTNNXLMG 714
PVSGG +GA TL FM G ++D +L LL F CG G AKL NN G
Sbjct: 144 PVSGGSLGAVAGTLTFMVGCVEDD--PNLELLI------FPCGGFLLGLTAKLCNNYCSG 195
Query: 715 XPRLAXADCXXHG 753
+A A+ G
Sbjct: 196 LIAIATAEAMNIG 208
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 814,118,690
Number of Sequences: 1657284
Number of extensions: 17246228
Number of successful extensions: 49666
Number of sequences better than 10.0: 356
Number of HSP's better than 10.0 without gapping: 47219
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 49456
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 74603367202
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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