Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP10_F_P09
(889 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9VXI1 Cluster: CG9914-PA; n=5; Diptera|Rep: CG9914-PA ... 187 4e-46
UniRef50_UPI0000588BF0 Cluster: PREDICTED: similar to 3-hydroxya... 165 1e-39
UniRef50_Q9Y2S2 Cluster: Lambda-crystallin homolog; n=30; Coelom... 161 2e-38
UniRef50_A7SBT1 Cluster: Predicted protein; n=2; Nematostella ve... 140 3e-32
UniRef50_Q1RLR0 Cluster: LOC570274 protein; n=4; Clupeocephala|R... 128 1e-28
UniRef50_Q2CEL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 96 9e-19
UniRef50_Q9D221 Cluster: Adult male hypothalamus cDNA, RIKEN ful... 96 1e-18
UniRef50_A5G288 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 95 2e-18
UniRef50_A4R503 Cluster: Putative uncharacterized protein; n=3; ... 94 4e-18
UniRef50_Q6SEY0 Cluster: 3-hydroxyacyl-CoA dehydrogenase domain ... 91 5e-17
UniRef50_Q98LG2 Cluster: Mll1034 protein; n=5; Alphaproteobacter... 87 4e-16
UniRef50_A1FMQ0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 85 2e-15
UniRef50_O29062 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A... 85 2e-15
UniRef50_A5A8P0 Cluster: Putative uncharacterized protein; n=3; ... 83 7e-15
UniRef50_A1B801 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 83 1e-14
UniRef50_Q0FUQ2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 82 2e-14
UniRef50_Q11EZ3 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 80 6e-14
UniRef50_A5N111 Cluster: Hbd2; n=5; Clostridiales|Rep: Hbd2 - Cl... 80 6e-14
UniRef50_Q39LC4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; B... 80 9e-14
UniRef50_A3VGB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 77 5e-13
UniRef50_Q5LTH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 75 2e-12
UniRef50_A6C4K6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 73 1e-11
UniRef50_Q160J3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 73 1e-11
UniRef50_Q9UX37 Cluster: 3-hydroxyacyl-CoA-dehydrogenase; n=4; S... 72 2e-11
UniRef50_Q93QG7 Cluster: Hydroxyacyl-CoA dehydrogenase; n=1; Bre... 71 3e-11
UniRef50_Q9HKW7 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenas... 71 3e-11
UniRef50_Q978T2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5; A... 71 3e-11
UniRef50_Q1GEJ8 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 71 4e-11
UniRef50_A3STE1 Cluster: Putative hydroxlacyl-CoA dehydrogenase;... 71 5e-11
UniRef50_Q5KYB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=6... 70 7e-11
UniRef50_A3YAS5 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 70 7e-11
UniRef50_Q97UK9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; S... 70 7e-11
UniRef50_UPI000050F939 Cluster: COG1250: 3-hydroxyacyl-CoA dehyd... 69 1e-10
UniRef50_Q7WLK3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 69 1e-10
UniRef50_Q24N80 Cluster: Putative uncharacterized protein; n=1; ... 69 1e-10
UniRef50_O29077 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; c... 69 1e-10
UniRef50_Q39HR3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=24; ... 69 2e-10
UniRef50_Q396V2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=9; B... 69 2e-10
UniRef50_Q2J5F5 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 69 2e-10
UniRef50_Q5L0D2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 68 3e-10
UniRef50_O28011 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; A... 68 3e-10
UniRef50_A6CP14 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 68 4e-10
UniRef50_Q5LPZ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 67 6e-10
UniRef50_Q73Q34 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 66 9e-10
UniRef50_A1FNB9 Cluster: 3-hydroxyacyl-CoA dehydrogenase precurs... 66 1e-09
UniRef50_O30218 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A... 64 5e-09
UniRef50_UPI00005102FD Cluster: COG1250: 3-hydroxyacyl-CoA dehyd... 64 6e-09
UniRef50_Q9RZ10 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 63 1e-08
UniRef50_Q2W2Y1 Cluster: Glyoxysomal fatty acid beta-oxidation m... 62 2e-08
UniRef50_Q28KL8 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 62 2e-08
UniRef50_Q988C8 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1... 61 4e-08
UniRef50_Q8XI27 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase N... 61 4e-08
UniRef50_Q7WCB1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 60 6e-08
UniRef50_Q5V0V6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 60 6e-08
UniRef50_Q11E57 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 60 7e-08
UniRef50_A1CC71 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 59 2e-07
UniRef50_Q5UWD9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; c... 59 2e-07
UniRef50_A1IEK7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 58 2e-07
UniRef50_Q0C7S2 Cluster: Putative uncharacterized protein; n=1; ... 58 2e-07
UniRef50_UPI000023E2B1 Cluster: hypothetical protein FG00090.1; ... 58 3e-07
UniRef50_Q5HKI5 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 58 4e-07
UniRef50_A5D5N2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 58 4e-07
UniRef50_Q5V357 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; H... 58 4e-07
UniRef50_Q2B4D1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 57 5e-07
UniRef50_A2TU34 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 57 5e-07
UniRef50_Q0UZL9 Cluster: Putative uncharacterized protein; n=1; ... 57 5e-07
UniRef50_Q4J598 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD bi... 57 7e-07
UniRef50_A5V325 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 57 7e-07
UniRef50_A0PRD1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase FadB... 57 7e-07
UniRef50_A0GEI2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 57 7e-07
UniRef50_Q9HRI4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7; c... 57 7e-07
UniRef50_A0RUN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 57 7e-07
UniRef50_P76083 Cluster: Probable 3-hydroxybutyryl-CoA dehydroge... 57 7e-07
UniRef50_Q9KBD3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=8... 56 1e-06
UniRef50_A4ALU9 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like pr... 56 1e-06
UniRef50_Q8G825 Cluster: Possible butyryl-CoA dehydrogenase; n=2... 56 2e-06
UniRef50_Q891F6 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=3... 55 2e-06
UniRef50_Q4J6T7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 55 2e-06
UniRef50_Q5P039 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; P... 55 3e-06
UniRef50_Q1DAC1 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 54 4e-06
UniRef50_A3U7V8 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 54 4e-06
UniRef50_A1SSP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 54 4e-06
UniRef50_A2QXC7 Cluster: Contig An11c0270, complete genome. prec... 54 4e-06
UniRef50_O69856 Cluster: Fatty acid oxidation complex alpha-subu... 54 5e-06
UniRef50_Q4J0Z7 Cluster: 3-hydroxyacyl-CoA dehydrogenase, C-term... 54 5e-06
UniRef50_Q89HA7 Cluster: Blr6087 protein; n=6; Proteobacteria|Re... 54 6e-06
UniRef50_Q12D24 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 54 6e-06
UniRef50_A0VLT7 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 54 6e-06
UniRef50_O29815 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A... 54 6e-06
UniRef50_Q397D0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 53 8e-06
UniRef50_A7PEM6 Cluster: Chromosome chr11 scaffold_13, whole gen... 53 8e-06
UniRef50_Q9XA30 Cluster: Putative 3-Hydroxyacyl-CoA dehydrogenas... 53 1e-05
UniRef50_Q0LRY2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 52 1e-05
UniRef50_A0LSM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 52 1e-05
UniRef50_Q67SZ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; S... 52 2e-05
UniRef50_Q68WH7 Cluster: Putative fatty acid oxidation complex t... 52 2e-05
UniRef50_Q0SEM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 52 3e-05
UniRef50_Q11TH9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 51 3e-05
UniRef50_Q7VRZ0 Cluster: Probable enoyl-CoA hydratase/3-hydroxya... 51 5e-05
UniRef50_Q6V1N6 Cluster: PlmT8; n=1; Streptomyces sp. HK803|Rep:... 51 5e-05
UniRef50_Q16836 Cluster: Hydroxyacyl-coenzyme A dehydrogenase, m... 51 5e-05
UniRef50_Q1IMY8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 50 6e-05
UniRef50_A5IDB6 Cluster: 3-hydroxyacyl CoA dehydrogenase; n=9; G... 50 6e-05
UniRef50_A1I839 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 50 6e-05
UniRef50_A7D676 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 50 6e-05
UniRef50_A4YDR4 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 50 6e-05
UniRef50_Q62DG4 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 50 8e-05
UniRef50_Q28UL9 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 50 8e-05
UniRef50_Q0FUM2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 50 8e-05
UniRef50_A0QZR0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 50 8e-05
UniRef50_P34439 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenas... 50 1e-04
UniRef50_Q46MP3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 49 1e-04
UniRef50_A6ERZ1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 49 1e-04
UniRef50_Q9ADL9 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase; ... 49 2e-04
UniRef50_A4FKS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 49 2e-04
UniRef50_A3M445 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 49 2e-04
UniRef50_A0JTB4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5; A... 49 2e-04
UniRef50_Q4PFL4 Cluster: Putative uncharacterized protein; n=1; ... 49 2e-04
UniRef50_Q2UUZ5 Cluster: RIB40 genomic DNA, SC009; n=4; Trichoco... 49 2e-04
UniRef50_Q2S2J8 Cluster: Fatty oxidation complex, alpha subunit;... 48 2e-04
UniRef50_A3YFA8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 48 3e-04
UniRef50_A0JVH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 48 4e-04
UniRef50_O44608 Cluster: Hydroxy-acyl-coa dehydrogenase protein ... 48 4e-04
UniRef50_Q02A28 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 47 6e-04
UniRef50_Q84T13 Cluster: L-3-hydroxyacyl-CoA dehydrogenase subun... 47 6e-04
UniRef50_Q0RVG8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; R... 47 7e-04
UniRef50_Q876X5 Cluster: Dehydrogenase; n=7; Pezizomycotina|Rep:... 47 7e-04
UniRef50_Q47M90 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 46 0.001
UniRef50_Q7RZ80 Cluster: Putative uncharacterized protein NCU043... 46 0.001
UniRef50_A2QA05 Cluster: Catalytic activity:; n=4; Trichocomacea... 46 0.001
UniRef50_Q7D836 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 46 0.001
UniRef50_Q3A7N5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 46 0.001
UniRef50_P45856 Cluster: Probable 3-hydroxybutyryl-CoA dehydroge... 46 0.001
UniRef50_A1SPQ6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 46 0.002
UniRef50_A4RUY4 Cluster: Predicted protein; n=5; cellular organi... 46 0.002
UniRef50_P45364 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 46 0.002
UniRef50_Q9RUA4 Cluster: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA... 45 0.002
UniRef50_Q1D1F2 Cluster: Fatty oxidation complex, alpha subunit ... 45 0.002
UniRef50_Q2VHK2 Cluster: Oxidoreductase; n=11; Lactobacillales|R... 45 0.003
UniRef50_Q0UJN7 Cluster: Predicted protein; n=1; Phaeosphaeria n... 45 0.003
UniRef50_Q5LKF7 Cluster: Fatty oxidation complex, alpha subunit;... 44 0.004
UniRef50_Q0LZ25 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 44 0.004
UniRef50_A4FGV2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 44 0.004
UniRef50_A5VHQ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 44 0.005
UniRef50_A4SW21 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 44 0.005
UniRef50_A1SEZ9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 44 0.005
UniRef50_A0Z5J4 Cluster: Enoyl-CoA hydratase; n=2; unclassified ... 44 0.005
UniRef50_O29090 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A... 44 0.007
UniRef50_Q1IIH2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 43 0.009
UniRef50_A1IFR8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 43 0.009
UniRef50_A7S4Z9 Cluster: Predicted protein; n=1; Nematostella ve... 43 0.009
UniRef50_A2QCM7 Cluster: Catalytic activity: precursor; n=5; Tri... 43 0.009
UniRef50_Q1YTH7 Cluster: Fatty oxidation complex, alpha subunit;... 43 0.012
UniRef50_A6GC68 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 43 0.012
UniRef50_A0IJE2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 43 0.012
UniRef50_UPI00006A277A Cluster: UPI00006A277A related cluster; n... 42 0.016
UniRef50_Q1GGC1 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 42 0.016
UniRef50_A6WDS7 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 42 0.016
UniRef50_Q39NP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 42 0.021
UniRef50_Q1EVV0 Cluster: Dihydrolipoyl dehydrogenase; n=6; Clost... 42 0.021
UniRef50_A6X670 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 42 0.021
UniRef50_Q4Q939 Cluster: Trifunctional enzyme alpha subunit, mit... 42 0.021
UniRef50_A0HAN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 42 0.028
UniRef50_Q5LVG3 Cluster: Enoyl-CoA hydratase/isomerase/3-hydroxy... 41 0.037
UniRef50_A1WHE6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; V... 41 0.037
UniRef50_Q6D2L7 Cluster: Fatty acid oxidation complex subunit al... 41 0.037
UniRef50_Q8YB80 Cluster: 3-HYDROXYBUTYRYL-COA DEHYDROGENASE; n=3... 41 0.048
UniRef50_A3ZYI9 Cluster: Fatty oxidation complex, alpha subunit ... 41 0.048
UniRef50_Q9AF94 Cluster: 3-hydroxyacyl-CoA-dehydrogenase; n=1; A... 40 0.064
UniRef50_Q1ATL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 40 0.085
UniRef50_A5WEP3 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 40 0.085
UniRef50_A1SQH4 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 40 0.085
UniRef50_Q88X11 Cluster: NADH peroxidase; n=1; Lactobacillus pla... 40 0.11
UniRef50_Q0SEV8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 40 0.11
UniRef50_A0J682 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 40 0.11
UniRef50_Q5V581 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; H... 40 0.11
UniRef50_Q6MHW5 Cluster: Glucose-inhibited division protein; n=1... 39 0.15
UniRef50_A1IDF2 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 39 0.15
UniRef50_P35484 Cluster: Dihydrolipoyl dehydrogenase; n=3; Achol... 39 0.15
UniRef50_Q8FX64 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 39 0.20
UniRef50_Q39TJ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like; n... 39 0.20
UniRef50_Q8KUG1 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=8; A... 39 0.20
UniRef50_Q0C0V2 Cluster: Oxidoreductase, FAD-binding; n=2; Prote... 39 0.20
UniRef50_A4SW27 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7; B... 39 0.20
UniRef50_Q0CYI1 Cluster: Predicted protein; n=1; Aspergillus ter... 39 0.20
UniRef50_Q45223 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=9... 39 0.20
UniRef50_Q1IUZ3 Cluster: UDP-glucose/GDP-mannose dehydrogenase; ... 38 0.26
UniRef50_A3D4X7 Cluster: FAD dependent oxidoreductase; n=3; Shew... 38 0.26
UniRef50_O17761 Cluster: Putative uncharacterized protein ech-8;... 38 0.26
UniRef50_UPI000018F68E Cluster: hypothetical protein Rm378p142; ... 38 0.34
UniRef50_Q5NW50 Cluster: DitN-like 3-hydroxyacyl-CoA dehydrogena... 38 0.34
UniRef50_A6P2M7 Cluster: Putative uncharacterized protein; n=2; ... 38 0.34
UniRef50_A4WWF6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 38 0.34
UniRef50_Q8U0F8 Cluster: NDP-sugar dehydrogenase; n=4; Thermococ... 38 0.34
UniRef50_P14218 Cluster: Dihydrolipoyl dehydrogenase; n=65; cell... 38 0.34
UniRef50_Q8G3X6 Cluster: Possible class I pyridine nucleotide-di... 38 0.45
UniRef50_Q8CXB6 Cluster: UDP-glucose:GDP-mannose dehydrogenase; ... 38 0.45
UniRef50_Q89SH2 Cluster: Blr2428 protein; n=7; Rhizobiales|Rep: ... 38 0.45
UniRef50_Q88YA7 Cluster: Bifunctional protein: amino acid aminot... 38 0.45
UniRef50_Q0SUA0 Cluster: Pyridine nucleotide-disulphide oxidored... 38 0.45
UniRef50_A4BGI3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; R... 38 0.45
UniRef50_O34324 Cluster: Dihydrolipoyl dehydrogenase; n=13; Baci... 38 0.45
UniRef50_P38169 Cluster: Kynurenine 3-monooxygenase; n=4; Saccha... 38 0.45
UniRef50_Q8RC01 Cluster: UDP-N-acetyl-D-mannosaminuronate dehydr... 37 0.60
UniRef50_Q82W31 Cluster: Phosphoribosylaminoimidazole carboxylas... 37 0.60
UniRef50_Q67L77 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 37 0.60
UniRef50_Q5LVD0 Cluster: Enoyl-CoA hydratase/isomerase/3-hydroxy... 37 0.60
UniRef50_Q4A6P9 Cluster: Putative mercuric reductase; n=1; Mycop... 37 0.60
UniRef50_Q1FP37 Cluster: NADH:flavin oxidoreductase/NADH oxidase... 37 0.60
UniRef50_A4XMY3 Cluster: Prephenate dehydrogenase; n=1; Caldicel... 37 0.60
UniRef50_Q9HJM0 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase r... 37 0.60
UniRef50_Q9X0U4 Cluster: Glutamate synthase, beta subunit; n=5; ... 37 0.79
UniRef50_Q8CX86 Cluster: UDP-glucose:GDP-mannose dehydrogenase; ... 37 0.79
UniRef50_Q7WIS8 Cluster: Putative enoyl-CoA isomerase; n=2; Bord... 37 0.79
UniRef50_Q8GP50 Cluster: Eps11H; n=13; Lactobacillales|Rep: Eps1... 37 0.79
UniRef50_A0LI43 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 37 0.79
UniRef50_Q9N5G1 Cluster: Dehydrogenases, short chain protein 15;... 37 0.79
UniRef50_Q9YBW6 Cluster: 3-hydroxyacyl-CoA dehydrogenase/3-hydro... 37 0.79
UniRef50_Q834J0 Cluster: Dihydrolipoyl dehydrogenase; n=3; Lacto... 36 1.0
UniRef50_Q28N18 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 36 1.0
UniRef50_Q1IMR6 Cluster: UDP-glucose/GDP-mannose dehydrogenase; ... 36 1.0
UniRef50_Q121N3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 36 1.0
UniRef50_Q0SCS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; A... 36 1.0
UniRef50_Q041G8 Cluster: Acetoin/pyruvate dehydrogenase complex,... 36 1.0
UniRef50_A3XHA5 Cluster: Regulatory protein; n=4; Flavobacteriac... 36 1.0
UniRef50_A3M5D5 Cluster: Dihydrolipoamide dehydrogenase; n=1; Ac... 36 1.0
UniRef50_O83080 Cluster: D-lactate dehydrogenase; n=1; Treponema... 36 1.0
UniRef50_P72357 Cluster: D-lactate dehydrogenase; n=28; Bacilli|... 36 1.0
UniRef50_Q892P7 Cluster: Dihydrolipoamide dehydrogenase; n=3; Cl... 36 1.4
UniRef50_Q6AA68 Cluster: UDP-glucose 6-dehydrogenase; n=3; root|... 36 1.4
UniRef50_Q2RJ81 Cluster: 4Fe-4S ferredoxin, iron-sulfur binding ... 36 1.4
UniRef50_Q2GH13 Cluster: FAD-dependent oxidoreductase; n=6; Anap... 36 1.4
UniRef50_Q6RK69 Cluster: D-lactate dehydrogenase; n=1; Lactobaci... 36 1.4
UniRef50_Q11BV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 36 1.4
UniRef50_A7BC28 Cluster: Putative uncharacterized protein; n=1; ... 36 1.4
UniRef50_A6VXM3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 36 1.4
UniRef50_A6LMV1 Cluster: Putative uncharacterized protein precur... 36 1.4
UniRef50_A3XPY3 Cluster: Putative uncharacterized protein; n=1; ... 36 1.4
UniRef50_A0W3T3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 36 1.4
UniRef50_A3LNF8 Cluster: Kynurenine 3-monooxygenase, mitochondri... 36 1.4
UniRef50_UPI00006A2AB5 Cluster: UPI00006A2AB5 related cluster; n... 36 1.8
UniRef50_Q8FRT3 Cluster: Putative 3-hydroxybutyryl-CoA dehydroge... 36 1.8
UniRef50_Q3AEV2 Cluster: Prephenate dehydrogenase; n=1; Carboxyd... 36 1.8
UniRef50_Q3IBS8 Cluster: Iron-sulfur-binding protein, glutamate ... 36 1.8
UniRef50_Q0F8T2 Cluster: Salicylate hydroxylase; n=1; alpha prot... 36 1.8
UniRef50_Q0B0P7 Cluster: NADP oxidoreductase, coenzyme F420-depe... 36 1.8
UniRef50_A3DJQ8 Cluster: NADH:flavin oxidoreductase/NADH oxidase... 36 1.8
UniRef50_Q0V6D4 Cluster: Putative uncharacterized protein; n=1; ... 36 1.8
UniRef50_O28262 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; A... 36 1.8
UniRef50_Q485S6 Cluster: Putative D-amino acid dehydrogenase, sm... 35 2.4
UniRef50_A7INS1 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 35 2.4
UniRef50_A5IXT8 Cluster: D-lactate dehydrogenase; n=3; Mycoplasm... 35 2.4
UniRef50_P77212 Cluster: Probable pyridine nucleotide-disulfide ... 35 2.4
UniRef50_Q97HK2 Cluster: 3-Hydroxyacyl-CoA dehydrogenase; n=1; C... 35 3.2
UniRef50_Q8E285 Cluster: Pyridine nucleotide-disulphide oxidored... 35 3.2
UniRef50_Q83EI9 Cluster: Thiamine biosynthesis oxidoreductase Th... 35 3.2
UniRef50_A1BCA2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 35 3.2
UniRef50_A1B712 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 35 3.2
UniRef50_A0V9H2 Cluster: 2-dehydropantoate 2-reductase precursor... 35 3.2
UniRef50_Q8F125 Cluster: Cell-division inhibitor; n=3; Bacteria|... 34 4.2
UniRef50_Q7NCM9 Cluster: Glr2949 protein; n=1; Gloeobacter viola... 34 4.2
UniRef50_Q2J6P6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=10; ... 34 4.2
UniRef50_Q0FK50 Cluster: Putative uncharacterized protein; n=1; ... 34 4.2
UniRef50_A5IAB6 Cluster: Pyridine nucleotide-disulfide oxidoredu... 34 4.2
UniRef50_A7RTC7 Cluster: Predicted protein; n=1; Nematostella ve... 34 4.2
UniRef50_P12045 Cluster: Phosphoribosylaminoimidazole carboxylas... 34 4.2
UniRef50_UPI0000510280 Cluster: COG1249: Pyruvate/2-oxoglutarate... 34 5.6
UniRef50_Q9RW59 Cluster: Dehydrogenase, putative; n=2; Deinococc... 34 5.6
UniRef50_Q97PL8 Cluster: Oxidoreductase, pyridine nucleotide-dis... 34 5.6
UniRef50_Q5FGZ4 Cluster: Dihydrolipoyl dehydrogenase; n=11; Rick... 34 5.6
UniRef50_Q4FKW7 Cluster: D-amino-acid dehydrogenase small chain;... 34 5.6
UniRef50_Q24PW4 Cluster: Dihydrolipoyl dehydrogenase; n=1; Desul... 34 5.6
UniRef50_Q1YK26 Cluster: Phosphoribosylaminoimidazole carboxylas... 34 5.6
UniRef50_Q18CC1 Cluster: E3 component of acetoin dehydrogenase e... 34 5.6
UniRef50_Q11ME9 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 34 5.6
UniRef50_Q0RL76 Cluster: Putative 3-hydroxybutyryl-CoA dehydroge... 34 5.6
UniRef50_A0YDQ2 Cluster: NADP oxidoreductase, coenzyme F420-depe... 34 5.6
UniRef50_Q92D17 Cluster: Lin1004 protein; n=10; Bacilli|Rep: Lin... 33 7.4
UniRef50_Q8XN08 Cluster: D-lactate dehydrogenase; n=4; Firmicute... 33 7.4
UniRef50_Q8A2W9 Cluster: Dihydrolipoyl dehydrogenase; n=7; Bacte... 33 7.4
UniRef50_Q3SL16 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 33 7.4
UniRef50_Q49111 Cluster: Dihydrolipoamide dehydrogenase; n=7; ro... 33 7.4
UniRef50_Q1NHB4 Cluster: Fatty oxidation complex, alpha subunit;... 33 7.4
UniRef50_Q1DAE6 Cluster: NADP oxidoreductase, coenzyme F420-depe... 33 7.4
UniRef50_A6CF61 Cluster: Soluble pyridine nucleotide transhydrog... 33 7.4
UniRef50_A5V9L0 Cluster: FAD dependent oxidoreductase precursor;... 33 7.4
UniRef50_A4WXD4 Cluster: Dimethylmenaquinone methyltransferase; ... 33 7.4
UniRef50_A3UGW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 33 7.4
UniRef50_A0UKE0 Cluster: FAD dependent oxidoreductase precursor;... 33 7.4
UniRef50_A0M4X2 Cluster: Kynurenine-3-monooxygenase-like protein... 33 7.4
UniRef50_Q23ZE9 Cluster: FAD dependent oxidoreductase family pro... 33 7.4
UniRef50_Q22X26 Cluster: Putative uncharacterized protein; n=1; ... 33 7.4
UniRef50_A7TI21 Cluster: Putative uncharacterized protein; n=1; ... 33 7.4
UniRef50_Q8TWI7 Cluster: UDP-N-acetylmuramoylalanine-D-glutamate... 33 7.4
UniRef50_A3DNE3 Cluster: FAD-dependent pyridine nucleotide-disul... 33 7.4
UniRef50_Q8ZAN0 Cluster: Fatty acid oxidation complex subunit al... 33 7.4
UniRef50_P75393 Cluster: Dihydrolipoyl dehydrogenase; n=6; Mycop... 33 7.4
UniRef50_UPI000038D9FE Cluster: COG1249: Pyruvate/2-oxoglutarate... 33 9.7
UniRef50_UPI000023D207 Cluster: hypothetical protein FG05450.1; ... 33 9.7
UniRef50_Q98N90 Cluster: Mll0243 protein; n=1; Mesorhizobium lot... 33 9.7
UniRef50_Q8KU48 Cluster: EF0114; n=1; Enterococcus faecalis|Rep:... 33 9.7
UniRef50_Q836Q9 Cluster: 6-phosphogluconate dehydrogenase, decar... 33 9.7
UniRef50_Q30V14 Cluster: D-isomer specific 2-hydroxyacid dehydro... 33 9.7
UniRef50_Q7X2D3 Cluster: D-amino acid oxidase; n=1; Arthrobacter... 33 9.7
UniRef50_Q4AI87 Cluster: FAD-dependent pyridine nucleotide-disul... 33 9.7
UniRef50_Q222Q6 Cluster: FAD dependent oxidoreductase precursor;... 33 9.7
UniRef50_Q128W2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 33 9.7
UniRef50_Q08VR6 Cluster: NADP oxidoreductase, coenzyme f420-depe... 33 9.7
UniRef50_Q03CK2 Cluster: Predicted dinucleotide-binding enzyme; ... 33 9.7
UniRef50_A6NVP0 Cluster: Putative uncharacterized protein; n=1; ... 33 9.7
UniRef50_A6M0T5 Cluster: Amine oxidase; n=6; Clostridium|Rep: Am... 33 9.7
UniRef50_A6GD93 Cluster: UDP-N-acetylmuramoylalanine--D-glutamat... 33 9.7
UniRef50_A6GBG1 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 33 9.7
UniRef50_A3ZZK1 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1... 33 9.7
UniRef50_A3YLN3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; C... 33 9.7
UniRef50_A3PFJ2 Cluster: NAD binding site:D-amino acid oxidase; ... 33 9.7
UniRef50_A7T9W4 Cluster: Predicted protein; n=1; Nematostella ve... 33 9.7
UniRef50_Q5KBI5 Cluster: Short chain 3-hydroxyacyl-CoA dehydroge... 33 9.7
UniRef50_A7EL57 Cluster: Putative uncharacterized protein; n=1; ... 33 9.7
UniRef50_Q8TZS4 Cluster: Glutamate synthase; n=78; cellular orga... 33 9.7
UniRef50_Q4J9Z6 Cluster: Conserved Crenarchaeal protein; n=3; Su... 33 9.7
UniRef50_A3H9B3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 33 9.7
UniRef50_P48638 Cluster: Glutathione reductase; n=57; Bacteria|R... 33 9.7
>UniRef50_Q9VXI1 Cluster: CG9914-PA; n=5; Diptera|Rep: CG9914-PA -
Drosophila melanogaster (Fruit fly)
Length = 315
Score = 187 bits (455), Expect = 4e-46
Identities = 87/151 (57%), Positives = 112/151 (74%)
Frame = +1
Query: 109 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG 288
K+EK+GIVGSGLIGRSW+MLFASVGYQV +YD++ +Q++ A+ + +L LE GLLRG
Sbjct: 4 KNEKVGIVGSGLIGRSWSMLFASVGYQVVLYDILPEQVSTALTATQKELQDLEAKGLLRG 63
Query: 289 ELKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXX 468
+L A++QF CI G+ DL+ VKGAIFVQEC+PE LDLKK +++ LD+VV NTI
Sbjct: 64 KLTAAQQFACISGTNDLKELVKGAIFVQECIPERLDLKKALYKQLDAVVGPNTILSSSTS 123
Query: 469 XXXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
LK+K+ V+VSHPVNPPYYVPL
Sbjct: 124 TFLPSLFSADLKNKANVLVSHPVNPPYYVPL 154
Score = 109 bits (262), Expect = 9e-23
Identities = 59/111 (53%), Positives = 69/111 (62%)
Frame = +2
Query: 557 PLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEVWRPR*RQ 736
PLVEIVPAPWTKPE KKTR +MEEIGQ+PV+L+REI+ F LNRIQYAIL+E WR
Sbjct: 153 PLVEIVPAPWTKPEWVKKTRALMEEIGQKPVTLSREIEGFALNRIQYAILNETWRLVEAG 212
Query: 737 SC*CXGY**KLCXKDLE*XMXFWGALXTXHXNAEGMQSYIDRYGETXXXVT 889
+ L F G L T H NAEGM +Y +RY T V+
Sbjct: 213 ILNVKDI-DSVMSNGLGPRYAFLGPLETAHLNAEGMANYFERYSNTIYAVS 262
>UniRef50_UPI0000588BF0 Cluster: PREDICTED: similar to
3-hydroxyacyl-coa dehyrogenase; n=5; Coelomata|Rep:
PREDICTED: similar to 3-hydroxyacyl-coa dehyrogenase -
Strongylocentrotus purpuratus
Length = 316
Score = 165 bits (401), Expect = 1e-39
Identities = 97/239 (40%), Positives = 128/239 (53%), Gaps = 6/239 (2%)
Frame = +1
Query: 109 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG 288
+S+KIGIVGSGLIGRSWAM+FAS G+ VT++D+ Q+++A++ IK QL L G+LRG
Sbjct: 2 ESQKIGIVGSGLIGRSWAMIFASAGFSVTIFDIEPSQVSNALKLIKSQLEELSESGMLRG 61
Query: 289 ELKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXX 468
L QF IKGS +E A+ GA FVQECV E L++K+KVF ++ V D I
Sbjct: 62 TLSVEAQFALIKGSNSMEEALAGASFVQECVFEKLEVKQKVFSEMEQYVSDGAILSSSSS 121
Query: 469 XXXXXXXXEGLKHKSQVIVSHPVNPPYYVPLG*NCPSTLD*A*SC*ENQGNYGRDRTAAS 648
E LK ++Q I+SHP+NPPYY PL P+ +Q R RT
Sbjct: 122 CIMPSQFTENLKRRNQCIISHPINPPYYAPLVEIIPAPW-------TDQSAIDRTRTIME 174
Query: 649 FFDQ-----GNRXICFESNSIRNPXXXXXXXXXXXXXMXR-ILIKVMSEGLGMXYAFLG 807
Q F +N I+ + + KVMS GLG+ YAFLG
Sbjct: 175 SVGQVPVTLKKEVPGFAANRIQYAIIAEVWRLVEGGVLSADDMDKVMSAGLGLRYAFLG 233
Score = 91.9 bits (218), Expect = 2e-17
Identities = 50/110 (45%), Positives = 62/110 (56%)
Frame = +2
Query: 557 PLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEVWRPR*RQ 736
PLVEI+PAPWT +TR IME +GQ PV+L +E+ F NRIQYAI+ EVWR
Sbjct: 151 PLVEIIPAPWTDQSAIDRTRTIMESVGQVPVTLKKEVPGFAANRIQYAIIAEVWR-LVEG 209
Query: 737 SC*CXGY**KLCXKDLE*XMXFWGALXTXHXNAEGMQSYIDRYGETXXXV 886
K+ L F G L H NAEGMQSY++RY ++ V
Sbjct: 210 GVLSADDMDKVMSAGLGLRYAFLGPLEVMHLNAEGMQSYMERYTQSIEHV 259
>UniRef50_Q9Y2S2 Cluster: Lambda-crystallin homolog; n=30;
Coelomata|Rep: Lambda-crystallin homolog - Homo sapiens
(Human)
Length = 319
Score = 161 bits (392), Expect = 2e-38
Identities = 74/145 (51%), Positives = 99/145 (68%)
Frame = +1
Query: 127 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASE 306
IVGSG+IGRSWAMLFAS G+QV +YD+ +QI +A+E+I+ ++ LE G L+G L E
Sbjct: 11 IVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGSLKGSLSVEE 70
Query: 307 QFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXX 486
Q I G +++ AV+GA+ +QECVPE+L+LKKK+F LDS++DD I
Sbjct: 71 QLSLISGCPNIQEAVEGAMHIQECVPEDLELKKKIFAQLDSIIDDRVILSSSTSCLMPSK 130
Query: 487 XXEGLKHKSQVIVSHPVNPPYYVPL 561
GL H Q IV+HPVNPPYY+PL
Sbjct: 131 LFAGLVHVKQCIVAHPVNPPYYIPL 155
Score = 81.8 bits (193), Expect = 2e-14
Identities = 45/105 (42%), Positives = 59/105 (56%)
Frame = +2
Query: 557 PLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEVWRPR*RQ 736
PLVE+VP P T P +T +M++IGQ P+ + +E+ FVLNR+QYAI+ E WR +
Sbjct: 154 PLVELVPHPETAPTTVDRTHALMKKIGQCPMRVQKEVAGFVLNRLQYAIISEAWR-LVEE 212
Query: 737 SC*CXGY**KLCXKDLE*XMXFWGALXTXHXNAEGMQSYIDRYGE 871
+ + L F G L T H NAEGM SY DRY E
Sbjct: 213 GIVSPSDLDLVMSEGLGMRYAFIGPLETMHLNAEGMLSYCDRYSE 257
>UniRef50_A7SBT1 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 322
Score = 140 bits (340), Expect = 3e-32
Identities = 70/159 (44%), Positives = 98/159 (61%), Gaps = 3/159 (1%)
Frame = +1
Query: 94 MASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLEND 273
M S + K+ ++GSGLIGR+W+ LF+S GY V +YD V+ Q+ +A E I QL LE+
Sbjct: 1 MTSSTEKGKVAVIGSGLIGRAWSTLFSSAGYHVALYDTVSSQLVNAKEAIISQLQELESK 60
Query: 274 GLLRGE--LKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDN- 444
LL+G A E F+ + + DL A+ G +VQEC PENL+LKKKVFQNL++ + +
Sbjct: 61 ELLKGRHCKTAQEAFKLVTTTDDLPQALNGVFYVQECTPENLELKKKVFQNLEATLSSSE 120
Query: 445 TIXXXXXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
I E L+ + + IV+HP+NPPYYVPL
Sbjct: 121 VILASSTSCIMPSKFTESLQLRQRCIVAHPINPPYYVPL 159
Score = 80.6 bits (190), Expect = 5e-14
Identities = 40/105 (38%), Positives = 60/105 (57%)
Frame = +2
Query: 557 PLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEVWRPR*RQ 736
PLVE++PAPWT V ++T ++M++IGQ PV L +E + F++NR+QYA++ E WR
Sbjct: 158 PLVEVIPAPWTDASVIEQTIKLMKDIGQSPVLLKKETNGFIVNRLQYALIAEAWRLVEEG 217
Query: 737 SC*CXGY**KLCXKDLE*XMXFWGALXTXHXNAEGMQSYIDRYGE 871
C + L G T H NA+G++ Y RYG+
Sbjct: 218 ICSPEDV-DTTMTEGLGLRYSLIGPFETMHLNADGIRDYCQRYGD 261
>UniRef50_Q1RLR0 Cluster: LOC570274 protein; n=4; Clupeocephala|Rep:
LOC570274 protein - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 327
Score = 128 bits (310), Expect = 1e-28
Identities = 66/154 (42%), Positives = 94/154 (61%)
Frame = +1
Query: 100 SKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGL 279
S K + I +VGSGLIGRSWAM+F S GY+V +YD Q + AI +I+ QL L+ +
Sbjct: 14 SSLKEKIITVVGSGLIGRSWAMVFLSGGYKVKLYDNKPGQASGAIAEIRKQLEELQQAKM 73
Query: 280 LRGELKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXX 459
LRG L A+EQ + DL+ A+ GA FVQE V E+L+ K+ VF ++ +V ++ I
Sbjct: 74 LRGNLSATEQLSRLSSHEDLQQALDGAFFVQESVFEDLEAKQSVFHAVEELVSESVILSS 133
Query: 460 XXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
++++++ IVSHPVNPPYYV L
Sbjct: 134 STSCLMPSNVFSQVQNRTRCIVSHPVNPPYYVRL 167
Score = 71.7 bits (168), Expect = 2e-11
Identities = 43/105 (40%), Positives = 57/105 (54%), Gaps = 1/105 (0%)
Frame = +2
Query: 560 LVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEVWRPR*RQS 739
LVE+VP P T P V + +M ++GQ PV L +EID F LNR+QYAI+ E WR +
Sbjct: 167 LVELVPHPETLPAVMEVAYSLMTDVGQAPVRLRKEIDGFALNRVQYAIIAESWR-LVQDG 225
Query: 740 C*CXGY**KLCXKDLE*XMXFWGALXTXHXNA-EGMQSYIDRYGE 871
+ + L F G + T H NA EGM+ Y+ RY E
Sbjct: 226 VISVKDIDLVMSEGLGMRYAFIGPIETMHLNAPEGMKDYLQRYSE 270
>UniRef50_Q2CEL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Rhodobacteraceae|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Oceanicola granulosus HTCC2516
Length = 312
Score = 96.3 bits (229), Expect = 9e-19
Identities = 55/147 (37%), Positives = 79/147 (53%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 297
K+ I+G+GLIG+SWA+ FA G VT++D A+ + L LE LL GE
Sbjct: 3 KVAIIGAGLIGQSWAIAFARGGCAVTLHDRDHAVADRALAVLPDALAALERMDLLGGET- 61
Query: 298 ASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 477
A I ++DL AV+GAI VQE PE L++K+ VF LD D + +
Sbjct: 62 ADAVGARIDAASDLADAVRGAIHVQENTPETLEVKRSVFAQLDDAADADAVIASSSSALL 121
Query: 478 XXXXXEGLKHKSQVIVSHPVNPPYYVP 558
+GL ++ +V+HP+NPP+ VP
Sbjct: 122 PSAFTDGLAGAARCLVAHPLNPPHLVP 148
Score = 64.1 bits (149), Expect = 5e-09
Identities = 28/59 (47%), Positives = 40/59 (67%)
Frame = +2
Query: 542 HLITYPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEVW 718
HL+ P VE+VP P T E +TR +M IGQ P+ +RE++ FV+NR+Q A+LDE +
Sbjct: 145 HLV--PAVELVPGPQTSAETVARTRALMSSIGQSPIETSREVEGFVMNRLQGALLDEAF 201
>UniRef50_Q9D221 Cluster: Adult male hypothalamus cDNA, RIKEN
full-length enriched library, clone:A230106J09
product:crystallin, lamda 1, full insert sequence; n=3;
Euarchontoglires|Rep: Adult male hypothalamus cDNA,
RIKEN full-length enriched library, clone:A230106J09
product:crystallin, lamda 1, full insert sequence - Mus
musculus (Mouse)
Length = 140
Score = 95.9 bits (228), Expect = 1e-18
Identities = 44/83 (53%), Positives = 61/83 (73%)
Frame = +1
Query: 127 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASE 306
IVGSGLIGRSWAMLFAS G++V +YD+ +QITDA+E+I+ ++ +LE G L+G L A
Sbjct: 11 IVGSGLIGRSWAMLFASGGFKVKLYDIEQQQITDALENIRKEMKSLEQSGSLKGSLSAER 70
Query: 307 QFQCIKGSTDLETAVKGAIFVQE 375
Q I G +L AV+GA+ +Q+
Sbjct: 71 QLSLISGCGNLAEAVEGAVHIQQ 93
>UniRef50_A5G288 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=2; Proteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Acidiphilium cryptum (strain JF-5)
Length = 312
Score = 95.5 bits (227), Expect = 2e-18
Identities = 50/148 (33%), Positives = 82/148 (55%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 297
KI +VG+GL+G +WA++FA G+ V VYD V AI I +L TLE GL+
Sbjct: 2 KIAVVGAGLVGSAWAIVFARAGHDVAVYDAVEGGADRAIGLIGDRLKTLEEVGLIEDAAA 61
Query: 298 ASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 477
A ++ ++ + L AV A ++QE V E ++ K+++F LD+VV T+
Sbjct: 62 AGQR---VRVAASLADAVADAAYIQESVFETVEQKRQIFAALDAVVGPETLIGSSSSGIP 118
Query: 478 XXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
+ + + + +++HPVNPPY +P+
Sbjct: 119 ASAFTDHVGCRERCLIAHPVNPPYLIPV 146
Score = 72.5 bits (170), Expect = 1e-11
Identities = 29/55 (52%), Positives = 40/55 (72%)
Frame = +2
Query: 557 PLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEVWR 721
P+VE+VPAPWT ++ R +ME +GQ+PV LTREI+ F LNR+Q +L E W+
Sbjct: 145 PVVELVPAPWTAAATVQRVRALMESVGQEPVELTREIEGFALNRLQGLLLAEAWK 199
>UniRef50_A4R503 Cluster: Putative uncharacterized protein; n=3;
Sordariomycetes|Rep: Putative uncharacterized protein -
Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 330
Score = 94.3 bits (224), Expect = 4e-18
Identities = 55/151 (36%), Positives = 84/151 (55%), Gaps = 3/151 (1%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 297
K+ I+G G IG SWA LF + G +V+ +DV + E + L L + GL++
Sbjct: 6 KVAIIGCGSIGASWAALFLAQGLEVSAFDVNPSAESFLRELVANALPVLSSLGLVKSSQA 65
Query: 298 ASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 477
+ I+ +TD+ TA+K A FVQE PE LD K+K+F+ + ++VD +TI
Sbjct: 66 TAAD---IEFTTDMATALKNASFVQENGPERLDFKQKLFRGVANLVDPDTIIATSSSGLT 122
Query: 478 XXXXXEGL--KHK-SQVIVSHPVNPPYYVPL 561
+GL +HK +V+V HP NPP+ +PL
Sbjct: 123 CSSIQQGLEAQHKPERVVVGHPFNPPHLIPL 153
Score = 41.5 bits (93), Expect = 0.028
Identities = 22/58 (37%), Positives = 33/58 (56%)
Frame = +2
Query: 542 HLITYPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEV 715
HLI PLVE+V T +T EE+G++ V + +E+ V NR+Q A++ EV
Sbjct: 149 HLI--PLVEVVGGEQTSQATISRTMGFYEEVGKKAVHIKKEVVGHVANRLQAALMREV 204
>UniRef50_Q6SEY0 Cluster: 3-hydroxyacyl-CoA dehydrogenase domain
protein; n=1; uncultured bacterium 582|Rep:
3-hydroxyacyl-CoA dehydrogenase domain protein -
uncultured bacterium 582
Length = 322
Score = 90.6 bits (215), Expect = 5e-17
Identities = 51/147 (34%), Positives = 78/147 (53%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
+ +VG+GLIG WA++FA G+QVT+ D+ ++ A + + QL LE L
Sbjct: 17 VSVVGAGLIGCGWAIVFARAGWQVTLQDIDLAKLQGAPKVLAVQLRMLEQHDLCADPAGI 76
Query: 301 SEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 480
+ I +DL+TAV +VQEC PE L LK+++F LD++ TI
Sbjct: 77 LAR---ISYESDLKTAVCEVDYVQECGPEVLGLKQELFSELDALTPPETILASSTSGLMA 133
Query: 481 XXXXEGLKHKSQVIVSHPVNPPYYVPL 561
L + + +V+HPVNPP+ VP+
Sbjct: 134 SQFSAHLAGRHRALVAHPVNPPHLVPV 160
Score = 60.9 bits (141), Expect = 4e-08
Identities = 27/60 (45%), Positives = 42/60 (70%)
Frame = +2
Query: 542 HLITYPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEVWR 721
HL+ P+VEI P+ WT PE+ + ++M +GQ PV++ +EI F+LNR+Q A+L+E R
Sbjct: 156 HLV--PVVEISPSEWTDPEIVRVVVDVMTGVGQTPVTVQKEIPGFLLNRLQGALLNEALR 213
>UniRef50_Q98LG2 Cluster: Mll1034 protein; n=5;
Alphaproteobacteria|Rep: Mll1034 protein - Rhizobium
loti (Mesorhizobium loti)
Length = 315
Score = 87.4 bits (207), Expect = 4e-16
Identities = 51/146 (34%), Positives = 74/146 (50%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
+ IVGSG IGR+WA+ FA G+ V ++D A + I+ L L + LLRG+
Sbjct: 4 VAIVGSGFIGRAWAISFARAGHDVRMWDQSPAATGGARDYIEGVLGDLAANDLLRGQ-SV 62
Query: 301 SEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 480
I DL A+ A VQE PENLD+K++VF +D + TI
Sbjct: 63 DTVLGRIATVGDLAEALADAAHVQENTPENLDVKREVFSLIDRLAGPQTIIASSTSALLP 122
Query: 481 XXXXEGLKHKSQVIVSHPVNPPYYVP 558
+ L+ + + +V HP+NPPY +P
Sbjct: 123 SKFTDHLQGRHRCLVVHPINPPYLIP 148
Score = 63.7 bits (148), Expect = 6e-09
Identities = 25/55 (45%), Positives = 38/55 (69%)
Frame = +2
Query: 557 PLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEVWR 721
P E+VPAPWT E +KTR + + G P+ + RE+D F++NR+Q A+L+E +R
Sbjct: 148 PAAEVVPAPWTSAETLEKTRAFLIDAGHAPLVMRRELDGFIMNRLQGALLEEAFR 202
>UniRef50_A1FMQ0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=3; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Pseudomonas putida W619
Length = 320
Score = 85.0 bits (201), Expect = 2e-15
Identities = 48/154 (31%), Positives = 81/154 (52%), Gaps = 1/154 (0%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLR-GELK 297
I IVG+GLIGR+WA++FA G+ V ++D+ + + ++ I+ +L+ L LL L
Sbjct: 14 IAIVGAGLIGRAWAIVFARAGHPVRLHDMDLQTMQNSHAYIEARLNELAEFDLLNDAPLT 73
Query: 298 ASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 477
+ C+ DL A++ + VQE V E ++ K +F +D++ + I
Sbjct: 74 VLARITCVP---DLADALRDVVLVQENVRETVEAKIDIFSRMDALAPKDAILASSTSWLP 130
Query: 478 XXXXXEGLKHKSQVIVSHPVNPPYYVPLG*NCPS 579
+ L + + +V+HP NPPY VPL CP+
Sbjct: 131 ASEFTKDLPGRGRCVVAHPTNPPYLVPLVELCPA 164
Score = 66.5 bits (155), Expect = 9e-10
Identities = 40/106 (37%), Positives = 55/106 (51%), Gaps = 1/106 (0%)
Frame = +2
Query: 557 PLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEVWRPR*RQ 736
PLVE+ PAPWT+ EV + EI GQ PV L+REI F+LNR+Q A+L+E ++ +
Sbjct: 157 PLVELCPAPWTESEVMVRAHEIYTAAGQSPVVLSREIHGFLLNRVQAAVLNECFKLH-EE 215
Query: 737 SC*CXGY**KLCXKDLE*XMXFWGALXTXHXNA-EGMQSYIDRYGE 871
++ L F G T NA G+ Y RYG+
Sbjct: 216 GFASSEDIDRVLKDGLALRWSFMGPFETIDLNAPAGVSDYAKRYGQ 261
>UniRef50_O29062 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 315
Score = 85.0 bits (201), Expect = 2e-15
Identities = 47/149 (31%), Positives = 74/149 (49%), Gaps = 1/149 (0%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 297
K+ +G+G +G SWA LFA G V VYD + + A I + TL ++ E
Sbjct: 4 KVACIGAGTVGASWASLFAWRGCDVAVYDPFPEALNRAEASIARTVSTL-SEIFSGSEDD 62
Query: 298 ASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 477
+K + +LE A+KGA +VQE E L++K+ +F+ +D++ + TI
Sbjct: 63 VKSALSRVKFTENLEEALKGAYYVQESAVEKLEVKRDLFEKMDAIAEPETILATSTSGLS 122
Query: 478 XXXXXEGL-KHKSQVIVSHPVNPPYYVPL 561
KH + I +HP NPP+ +PL
Sbjct: 123 ISEIQTAARKHPERCITAHPYNPPHLIPL 151
Score = 44.4 bits (100), Expect = 0.004
Identities = 22/57 (38%), Positives = 34/57 (59%)
Frame = +2
Query: 542 HLITYPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDE 712
HLI PLVE+VP T +KT E ME +G++P+ + +++ V NR+ A+ E
Sbjct: 147 HLI--PLVEVVPRKQTDESCTEKTVEFMERMGKKPIVVKKDVPGMVANRLAAALWRE 201
>UniRef50_A5A8P0 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 284
Score = 83.4 bits (197), Expect = 7e-15
Identities = 39/122 (31%), Positives = 67/122 (54%)
Frame = +1
Query: 196 VYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASEQFQCIKGSTDLETAVKGAIFVQE 375
+YD+ KQ+ A+E+++ L L+ GL RG L A E + +T L +K AI++QE
Sbjct: 1 MYDISEKQLQVALENVEKNLRKLDEHGLQRGNLSADEALLRVSTTTSLNEVMKNAIYMQE 60
Query: 376 CVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYV 555
E+L+ + + ++ +D + D TI +GL +K + ++ HPVNPP ++
Sbjct: 61 SALEDLNFRIQFYKVIDEIADPTTILASSTSTIPASKFTDGLINKERCLIVHPVNPPLFL 120
Query: 556 PL 561
PL
Sbjct: 121 PL 122
Score = 69.3 bits (162), Expect = 1e-10
Identities = 38/103 (36%), Positives = 52/103 (50%)
Frame = +2
Query: 557 PLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEVWRPR*RQ 736
PL E+VPAPWT + + EIM + Q+PV L +E+ FV+NR+Q+A+L E WR
Sbjct: 121 PLTELVPAPWTSQDTVDRAAEIMRSVKQEPVKLKKEVLGFVVNRLQFALLAETWR-LVAD 179
Query: 737 SC*CXGY**KLCXKDLE*XMXFWGALXTXHXNAEGMQSYIDRY 865
+ L F G T H NA G++ Y RY
Sbjct: 180 GVIGVNDVDAVMSAGLGPRYAFNGTCETVHLNAFGVRDYFKRY 222
>UniRef50_A1B801 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Rhodobacteraceae|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Paracoccus denitrificans (strain Pd 1222)
Length = 311
Score = 82.6 bits (195), Expect = 1e-14
Identities = 51/147 (34%), Positives = 73/147 (49%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
I IVG+GLIGR+WA +FA G+ V V+D+ + + DI + G + A
Sbjct: 4 IAIVGAGLIGRAWAFVFARAGFDVRVWDLDPQVLERLDGDIAAMVAQTAPFGQAGADPDA 63
Query: 301 SEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 480
+ I+ DL A+ GA VQE PE L +K+++F LD + I
Sbjct: 64 TAAR--IRAVPDLAGALDGAELVQESGPEVLAIKRELFARLDGLAAAGVILASSSSALMA 121
Query: 481 XXXXEGLKHKSQVIVSHPVNPPYYVPL 561
EGL S+ +V HPVNPP+ VP+
Sbjct: 122 SAFAEGLPGASRCLVGHPVNPPHLVPV 148
Score = 62.1 bits (144), Expect = 2e-08
Identities = 30/60 (50%), Positives = 39/60 (65%)
Frame = +2
Query: 542 HLITYPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEVWR 721
HL+ P+VEI PAP+T P + + R+I GQ PV L REID F+LNR+Q +L E R
Sbjct: 144 HLV--PVVEIAPAPFTDPVITARARDIYARAGQVPVMLKREIDGFILNRLQAVVLAESLR 201
>UniRef50_Q0FUQ2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Alphaproteobacteria|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Roseovarius sp. HTCC2601
Length = 316
Score = 82.2 bits (194), Expect = 2e-14
Identities = 48/154 (31%), Positives = 75/154 (48%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 297
KI I+GSG+IG SWA+++A G V +Y+ A++ ++ L + + LLR
Sbjct: 5 KIAILGSGVIGASWAIVYARSGCDVAIYERSEAFRDSAMQRLESSLAS--SASLLRDGET 62
Query: 298 ASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 477
+ I LE AV GA FV EC+ ENLD K+++F L+ + I
Sbjct: 63 VQDVLARITLHDTLEAAVAGADFVHECIVENLDSKRQIFAALNDAAEPEAILASTTSSFP 122
Query: 478 XXXXXEGLKHKSQVIVSHPVNPPYYVPLG*NCPS 579
L + + I+ HP PP+ +P+ CP+
Sbjct: 123 VSHFASDLACRDRCIIVHPATPPHLLPVTEICPA 156
Score = 59.3 bits (137), Expect = 1e-07
Identities = 28/58 (48%), Positives = 41/58 (70%)
Frame = +2
Query: 542 HLITYPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEV 715
HL+ P+ EI PAP+T EV+++T M E GQ PV + +E++ FVLNR+Q A+L E+
Sbjct: 146 HLL--PVTEICPAPFTSAEVSERTTAFMRECGQIPVRIKKEVEGFVLNRMQAALLVEM 201
>UniRef50_Q11EZ3 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=3; Bacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Mesorhizobium sp. (strain BNC1)
Length = 318
Score = 80.2 bits (189), Expect = 6e-14
Identities = 47/147 (31%), Positives = 73/147 (49%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
I IVG+G IG ++A+LFAS G V ++D + A +++ +L L L
Sbjct: 13 ISIVGAGSIGVAFAVLFASRGASVRIWDALPDAFDRAANELRSRLEMLAKASALSEP--P 70
Query: 301 SEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 480
E I +L A+ GA VQEC PEN+DLK +F+ L + D+ +
Sbjct: 71 DEISSRISWHRNLAEALDGADLVQECAPENIDLKVDLFRWLADLTPDHVVLASSSSALIA 130
Query: 481 XXXXEGLKHKSQVIVSHPVNPPYYVPL 561
++ + +V+V HP NPPY +P+
Sbjct: 131 SLIAPDIEIRRRVLVGHPGNPPYLIPV 157
Score = 45.6 bits (103), Expect = 0.002
Identities = 19/54 (35%), Positives = 33/54 (61%)
Frame = +2
Query: 557 PLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEVW 718
P++E+VP+P T + + EI +PV + RE++ F+ NR+Q A+L E +
Sbjct: 156 PVIEVVPSPETAQAIIDRAFEIYRNSHLKPVLVRREVEGFIFNRLQGAVLREAY 209
>UniRef50_A5N111 Cluster: Hbd2; n=5; Clostridiales|Rep: Hbd2 -
Clostridium kluyveri DSM 555
Length = 319
Score = 80.2 bits (189), Expect = 6e-14
Identities = 43/149 (28%), Positives = 71/149 (47%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
+ + ++G+G +G L A G V ++ + IK L LE G ++ +
Sbjct: 4 KNVAVLGTGTMGNGIVQLCAESGLNVNMFGRTDASLERGFTSIKTSLKNLEEKGKIKTNI 63
Query: 295 KASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 474
+ E + IKG +E AV+G FV EC+ E+L+LK++VF LD + I
Sbjct: 64 -SKEILKRIKGVKTIEEAVEGVDFVIECIAEDLELKQEVFSKLDEICAPEVILASNTSGL 122
Query: 475 XXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
KH +V+++H NPP ++PL
Sbjct: 123 SPTDIAINTKHPERVVIAHFWNPPQFIPL 151
Score = 40.7 bits (91), Expect = 0.048
Identities = 20/52 (38%), Positives = 31/52 (59%)
Frame = +2
Query: 557 PLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDE 712
PLVE+VP T + T + +E IG++ V + +E F+ NR+Q A+L E
Sbjct: 150 PLVEVVPGKHTDSKTVDITMDWIEHIGKKGVKMRKECLGFIGNRLQLALLRE 201
>UniRef50_Q39LC4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Burkholderia sp. 383|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 333
Score = 79.8 bits (188), Expect = 9e-14
Identities = 47/149 (31%), Positives = 73/149 (48%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
E +GI+G+G IG SWA LF + G +V VYD + + +++ +LE GL R
Sbjct: 12 EVVGILGAGTIGASWAALFLAAGLEVDVYDPSPEGEAFVRDYVRHAWPSLERLGLARRGD 71
Query: 295 KASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 474
+F E AV A FVQE VPE +++K +++ ++ +D I
Sbjct: 72 PGRLRFVATP-----EEAVARAQFVQESVPERIEIKHALYRRIEDHLDPRAIVCSSASGL 126
Query: 475 XXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
G K+ + I+ HP NPP+ +PL
Sbjct: 127 LVKEMQAGWKNPGRFILGHPFNPPHLIPL 155
>UniRef50_A3VGB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Rhodobacterales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Rhodobacterales bacterium HTCC2654
Length = 324
Score = 77.4 bits (182), Expect = 5e-13
Identities = 47/157 (29%), Positives = 78/157 (49%), Gaps = 1/157 (0%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITD-AIEDIKYQLHTLENDGLLRGEL 294
++ +G G +G WA +FA G++V +YD A I A+ I+ L L + + GE
Sbjct: 3 RVVCIGVGTVGCGWATVFARAGHEVVLYDADADAIAARALPRIEATLEQLGRE-MPTGET 61
Query: 295 KASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 474
A + + I+ + LE A+ GA VQE V E+L +K+ +F + + D+ +
Sbjct: 62 PADIRAR-IRVAGSLEEALSGAEVVQESVREDLAIKRALFDEIGAAAPDDCLLLSSTSAL 120
Query: 475 XXXXXXEGLKHKSQVIVSHPVNPPYYVPLG*NCPSTL 585
+ H + +V HPVNPP ++PL C + L
Sbjct: 121 PGSQFLSDIPHPERALVGHPVNPPSHIPLVELCATPL 157
Score = 56.8 bits (131), Expect = 7e-07
Identities = 22/52 (42%), Positives = 34/52 (65%)
Frame = +2
Query: 557 PLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDE 712
PLVE+ P T PE ++ R E G +P+++ +EID F+LNR+QY ++ E
Sbjct: 148 PLVELCATPLTAPETVERARRFYTEAGMEPITVNKEIDGFILNRLQYTLVAE 199
>UniRef50_Q5LTH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=16; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase family protein -
Silicibacter pomeroyi
Length = 487
Score = 74.9 bits (176), Expect = 2e-12
Identities = 50/148 (33%), Positives = 71/148 (47%), Gaps = 3/148 (2%)
Frame = +1
Query: 127 IVGSGLIGRSWAMLFASVGYQVTVYDV---VAKQITDAIEDIKYQLHTLENDGLLRGELK 297
I+G G+IG WA F G+ V V+D ++I + + + + L L +D L E K
Sbjct: 6 IIGGGVIGGGWAARFLLNGWDVRVFDPDPEAERKIGEVLANARRSLPGL-SDMPLPPEGK 64
Query: 298 ASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 477
S DL AV GA ++QE VPE LDLK KV++++ D I
Sbjct: 65 LSFH-------ADLGEAVTGAAWIQESVPERLDLKLKVYRSIQEACDPGAILGSSTSGFK 117
Query: 478 XXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
EG Q++V+HP NP Y +PL
Sbjct: 118 PSELQEGALRPGQIVVTHPFNPVYLLPL 145
Score = 46.4 bits (105), Expect = 0.001
Identities = 21/55 (38%), Positives = 34/55 (61%)
Frame = +2
Query: 557 PLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEVWR 721
PL+E+V P PE+ ++ +EIM +GQ P+ + +EID + +R L+ VWR
Sbjct: 144 PLIELVTTPENSPEMIERAKEIMRGLGQFPLHVRKEIDAHIADR----FLEAVWR 194
>UniRef50_A6C4K6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Planctomyces maris DSM 8797
Length = 311
Score = 72.9 bits (171), Expect = 1e-11
Identities = 44/151 (29%), Positives = 74/151 (49%), Gaps = 2/151 (1%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLL--RG 288
++IGI+G+GLIG SWA FA+ G +V ++DV A E L L + L+ +
Sbjct: 2 QEIGILGAGLIGASWATFFAAQGLRVRIFDVNNTVKQQAQELSVQNLQRLADLELISRKD 61
Query: 289 ELKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXX 468
A E+ + +L T V+ +VQE V E+ ++K V+Q + + I
Sbjct: 62 AATAEEKLNVVDSLAELLTDVE---YVQESVIEDYEIKADVYQQFEQYAPEAAILGSSSS 118
Query: 469 XXXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
++H + +++HP NPP+ +PL
Sbjct: 119 GLLMTRMQTVMQHPGRALIAHPFNPPHLIPL 149
Score = 44.0 bits (99), Expect = 0.005
Identities = 22/57 (38%), Positives = 32/57 (56%)
Frame = +2
Query: 542 HLITYPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDE 712
HLI PLVE+VP T E + +E + +G+ PV L RE+ + NR+ A+ E
Sbjct: 145 HLI--PLVELVPGEQTATETMETVKEFFQGLGKHPVILNREVPGHIANRLAAAVWRE 199
>UniRef50_Q160J3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Roseobacter denitrificans OCh 114|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Roseobacter
denitrificans (strain ATCC 33942 / OCh 114)
(Erythrobactersp. (strain OCh 114)) (Roseobacter
denitrificans)
Length = 331
Score = 72.5 bits (170), Expect = 1e-11
Identities = 41/147 (27%), Positives = 71/147 (48%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
+ I+G GLIG++WA +F G +VT+YD + + A + ++ L+ E
Sbjct: 19 VAIIGCGLIGQAWATVFLRAGMRVTLYDAASGLVEQAKAQVIERMTEFARFDLVTHETLE 78
Query: 301 SEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 480
I+ + LE AV A ++QE E LD+K ++ + +D + +
Sbjct: 79 RAPAH-IELADTLEDAVSAADYIQESGSEALDVKIELTREIDRFAAPHVVIGSSTSGITA 137
Query: 481 XXXXEGLKHKSQVIVSHPVNPPYYVPL 561
E +K + + +V HP+NPP+ VPL
Sbjct: 138 SRYSETIKGRERCLVVHPINPPHLVPL 164
Score = 64.9 bits (151), Expect = 3e-09
Identities = 41/110 (37%), Positives = 54/110 (49%), Gaps = 1/110 (0%)
Frame = +2
Query: 542 HLITYPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEVWR 721
HL+ PLVE+VPAPWT +++ IGQ P+ L REID FV+NR+Q A+L E +
Sbjct: 160 HLV--PLVEVVPAPWTAQSAVDTVHDLLSAIGQVPILLNREIDGFVVNRLQGALLREAFH 217
Query: 722 PR*RQSC*CXGY**KLCXKDLE*XMXFWGALXTXHXNAE-GMQSYIDRYG 868
Q K L G T H NA G+ Y+ R+G
Sbjct: 218 LL-DQGVASRKDIDKAISDGLGLRWSLMGPFETIHLNAPGGVSDYVRRFG 266
>UniRef50_Q9UX37 Cluster: 3-hydroxyacyl-CoA-dehydrogenase; n=4;
Sulfolobaceae|Rep: 3-hydroxyacyl-CoA-dehydrogenase -
Sulfolobus solfataricus
Length = 324
Score = 71.7 bits (168), Expect = 2e-11
Identities = 38/149 (25%), Positives = 73/149 (48%), Gaps = 1/149 (0%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 297
K+ ++G+G+IG W L + GY+V +Y + + A+ + L L+N G++ E
Sbjct: 10 KVAVIGAGVIGVGWTTLLLAKGYKVNLYTEKKETLEKALAKVSAYLVNLKNLGMINEE-- 67
Query: 298 ASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 477
+ G T ++ A+ FV E + E+ KK +F+ LD+ + + I
Sbjct: 68 PESYITNLTGITKIDDAIHNVDFVIEAIIEDYTAKKNLFKLLDTQLPQDIIIASSTSGLL 127
Query: 478 XXXXXEG-LKHKSQVIVSHPVNPPYYVPL 561
+ ++H + +++HP NPP+ +PL
Sbjct: 128 MTEIQKAMIRHPERGVIAHPWNPPHLLPL 156
Score = 46.0 bits (104), Expect = 0.001
Identities = 24/57 (42%), Positives = 34/57 (59%)
Frame = +2
Query: 542 HLITYPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDE 712
HL+ PLVEIVP T E TRE ME++ + V L +E+ F+ NR+ +A+ E
Sbjct: 152 HLL--PLVEIVPGEKTSKETVDLTREFMEKLDRVVVLLRKEVPGFIGNRLAFALFRE 206
>UniRef50_Q93QG7 Cluster: Hydroxyacyl-CoA dehydrogenase; n=1;
Brevibacterium sp. HCU|Rep: Hydroxyacyl-CoA
dehydrogenase - Brevibacterium sp. HCU
Length = 316
Score = 71.3 bits (167), Expect = 3e-11
Identities = 43/143 (30%), Positives = 71/143 (49%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
+GI G+G IG ++A+LFA G+ V ++D + + I ++ L+ LL
Sbjct: 7 VGIFGAGSIGTAFALLFADAGFAVRIFDPDPSALERSRHVIDQRITELQRFTLLASN--P 64
Query: 301 SEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 480
SE + I+ + TA GAI VQE PE++ K+ +F++L +V D TI
Sbjct: 65 SEVRELIEIVSSARTAASGAILVQEAGPEDVQTKQHIFEDLTAVTSDETILASASSAIPS 124
Query: 481 XXXXEGLKHKSQVIVSHPVNPPY 549
+ + + ++ HP NPPY
Sbjct: 125 SRFVD-VHSAFRSLIGHPGNPPY 146
Score = 43.2 bits (97), Expect = 0.009
Identities = 20/53 (37%), Positives = 32/53 (60%)
Frame = +2
Query: 560 LVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEVW 718
+VE+V P T+ + + ++ E+ G V + RE+D FV NRIQ A+L E +
Sbjct: 150 VVELVGNPSTEEQTILRAGQLYEQAGLSAVRVNREVDGFVFNRIQGAVLREAY 202
>UniRef50_Q9HKW7 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenase;
n=2; Thermoplasmatales|Rep: Probable 3-hydroxyacyl-CoA
dehydrogenase - Thermoplasma acidophilum
Length = 291
Score = 71.3 bits (167), Expect = 3e-11
Identities = 49/142 (34%), Positives = 71/142 (50%), Gaps = 3/142 (2%)
Frame = +1
Query: 127 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIK---YQLHTLENDGLLRGELK 297
+VGSG++G+ A +FA GY VT+ DV + +A+ IK Y L L G + E +
Sbjct: 8 VVGSGVMGQGIAQVFARSGYPVTIIDVRDDILANAVRSIKEGRYGLMNLVKKGTMT-ESE 66
Query: 298 ASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 477
+ I+ ST + + A V E VPENLDLK+KVF +++ V +N I
Sbjct: 67 VDKIMGKIRTSTSYGS-LSDADIVVEAVPENLDLKRKVFIDIEKNVSENAIIASNTSGIT 125
Query: 478 XXXXXEGLKHKSQVIVSHPVNP 543
+ LK K + I H NP
Sbjct: 126 IAEIAQDLKKKDRAIGMHWFNP 147
>UniRef50_Q978T2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5;
Archaea|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Thermoplasma volcanium
Length = 659
Score = 71.3 bits (167), Expect = 3e-11
Identities = 45/148 (30%), Positives = 67/148 (45%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 297
K+ ++GSG++G A A GY V + D+ + A +I L L G L + K
Sbjct: 5 KVTVIGSGIMGHGIAETIALAGYDVNLEDISDDVLAKAKAEIDASLDRLVKSGKLSDKTK 64
Query: 298 ASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 477
+ T + +VK A V E VPE LD+K++VF LD ++ I
Sbjct: 65 VLGRIHYF---TSIPESVKDADLVIEAVPEILDIKRQVFAQLDQSTKEDAILATNTSNIR 121
Query: 478 XXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
EG+K K +V+ H NPP + L
Sbjct: 122 LTEIAEGVKKKGKVVGMHFFNPPVVLKL 149
>UniRef50_Q1GEJ8 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=17; Bacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase NAD-binding - Silicibacter sp. (strain
TM1040)
Length = 491
Score = 70.9 bits (166), Expect = 4e-11
Identities = 47/149 (31%), Positives = 70/149 (46%), Gaps = 4/149 (2%)
Frame = +1
Query: 127 IVGSGLIGRSWAMLFASVGYQVTVYDV---VAKQITDAIEDIKYQLHTLENDGLL-RGEL 294
I+G G+IG WA F G+ V V+D ++I D + + + L L N L G L
Sbjct: 7 IIGGGVIGGGWAARFLLNGWDVRVFDPDPEAERKIGDVLANARRSLPGLGNVALPPEGSL 66
Query: 295 KASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 474
E L V+G +VQE VPE LDLK+KV+ L++ +
Sbjct: 67 SYHET---------LAETVQGVDWVQESVPERLDLKQKVYAELEAHAPGGAVIGSSTSGY 117
Query: 475 XXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
+G + +Q++V+HP NP Y +PL
Sbjct: 118 KPSQLQDGFTNAAQIVVAHPFNPVYLMPL 146
Score = 43.6 bits (98), Expect = 0.007
Identities = 23/55 (41%), Positives = 31/55 (56%)
Frame = +2
Query: 557 PLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEVWR 721
PLVE+V PE+ K + I+ EIG P+ L +EID V +R L+ VWR
Sbjct: 145 PLVEVVTTDVNTPEMIAKAKAIITEIGMYPLHLKKEIDAHVADR----FLEAVWR 195
>UniRef50_A3STE1 Cluster: Putative hydroxlacyl-CoA dehydrogenase;
n=3; Rhodobacteraceae|Rep: Putative hydroxlacyl-CoA
dehydrogenase - Sulfitobacter sp. NAS-14.1
Length = 309
Score = 70.5 bits (165), Expect = 5e-11
Identities = 41/148 (27%), Positives = 69/148 (46%), Gaps = 1/148 (0%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
+ ++G GLIG SWA LF G+ V +D + L L+ E+ A
Sbjct: 7 VAVIGCGLIGASWAALFQHAGHTVRAWDPDTGARDGFAARVAGPLAQLQ-------EISA 59
Query: 301 SEQFQ-CIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 477
Q + L+ A++ + +QE PEN+ LK +++ ++S+V + I
Sbjct: 60 GAAPQGALSTHESLQDALQDVVLIQENAPENVPLKHQLYAQIESIVAPDVIIASSTSAHP 119
Query: 478 XXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
G++H ++I +HP NPP+ VPL
Sbjct: 120 WSDLVPGMQHPDRLITAHPFNPPHLVPL 147
>UniRef50_Q5KYB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=6;
Bacillaceae|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Geobacillus kaustophilus
Length = 287
Score = 70.1 bits (164), Expect = 7e-11
Identities = 47/152 (30%), Positives = 77/152 (50%), Gaps = 3/152 (1%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
E++ +VGSG++GR A + A G+Q T+ D+ +Q+ A ++I ++ G+ RG+L
Sbjct: 3 ERLVVVGSGVMGRGIAYVGAVGGFQTTLVDIKQEQLESAQKEIA----SIFEQGVARGKL 58
Query: 295 KASEQFQC---IKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXX 465
SE+ + + S DL AV+ A V E VPE L+LKK+VF+ +D+ +
Sbjct: 59 TDSERQEAEARLSYSLDLAAAVRDADLVIEAVPEKLELKKQVFETIDAHAPASCYFATNT 118
Query: 466 XXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
K +VI H NP + + L
Sbjct: 119 STMSPTEIGSFTKRPERVIAMHFFNPVHKMKL 150
>UniRef50_A3YAS5 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Marinomonas sp. MED121|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Marinomonas sp. MED121
Length = 323
Score = 70.1 bits (164), Expect = 7e-11
Identities = 41/148 (27%), Positives = 66/148 (44%), Gaps = 1/148 (0%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 297
K+G++G+G+IG +WA+ + +G +V YD + + T+E GL G K
Sbjct: 12 KVGVIGTGVIGGAWALHYLRMGMEVVAYDPGPNSKEKLLTMVDNIWPTIEKLGLREGASK 71
Query: 298 ASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 477
+F L+ +QE PE LD K+ +F +LD +V + +
Sbjct: 72 DKLRF-----VDSLDALANQVEVIQESTPERLDAKRSLFADLDCIVPADVVIISSTSGFA 126
Query: 478 XXXXXEGLK-HKSQVIVSHPVNPPYYVP 558
L+ + +V HP NPPY VP
Sbjct: 127 MTDMANELETQPDRFVVGHPFNPPYLVP 154
>UniRef50_Q97UK9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2;
Sulfolobus|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Sulfolobus solfataricus
Length = 384
Score = 70.1 bits (164), Expect = 7e-11
Identities = 46/144 (31%), Positives = 71/144 (49%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
+KIG+VG+G +G A + A Y V+V D+ + A E I L+ G ++
Sbjct: 4 KKIGVVGAGTMGHGIAEVSALANYNVSVVDISWDFLNRAKERIMESLNKFYEKGQIKE-- 61
Query: 295 KASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 474
K + + I+ ST + ++ A FV E VPE ++LK+KVF+ LDS+ +T
Sbjct: 62 KPEDIMKRIEFSTSYDV-MRDADFVIEAVPEIIELKRKVFETLDSITPSHTFLASNTSSI 120
Query: 475 XXXXXXEGLKHKSQVIVSHPVNPP 546
E K K ++I H NPP
Sbjct: 121 PISTIAEVTKRKEKIIGMHFFNPP 144
Score = 40.3 bits (90), Expect = 0.064
Identities = 20/54 (37%), Positives = 32/54 (59%)
Frame = +2
Query: 560 LVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEVWR 721
LVEIVP+ +T E + T ++ +++ + PV L E+ FV NRI ++ E R
Sbjct: 149 LVEIVPSKYTSDETIEVTIDLAKKMNKIPVKLKVEVPGFVSNRIFLRLMQEACR 202
>UniRef50_UPI000050F939 Cluster: COG1250: 3-hydroxyacyl-CoA
dehydrogenase; n=1; Brevibacterium linens BL2|Rep:
COG1250: 3-hydroxyacyl-CoA dehydrogenase -
Brevibacterium linens BL2
Length = 314
Score = 69.3 bits (162), Expect = 1e-10
Identities = 47/149 (31%), Positives = 75/149 (50%), Gaps = 2/149 (1%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
+ ++G+G IGRS+A LFA GY V V+D + + + +++ ++ D ++ A
Sbjct: 5 VAVIGAGTIGRSFAWLFARSGYPVQVFD-PRPDLAEVVTELQAEVSA---DAAAH-DMLA 59
Query: 301 SEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 480
SE I + +ETAV GA FVQE PE+ K K+F + + + I
Sbjct: 60 SE-LGTISLAESVETAVAGASFVQESGPEDPQAKPKLFAQIAAAAPKDAIFATSSSTIPA 118
Query: 481 XXXXEGLKHK--SQVIVSHPVNPPYYVPL 561
L + ++VIV HP NPP+ +PL
Sbjct: 119 SLIARHLPPEVAARVIVGHPFNPPHLMPL 147
Score = 52.8 bits (121), Expect = 1e-05
Identities = 23/52 (44%), Positives = 34/52 (65%)
Frame = +2
Query: 557 PLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDE 712
PLVE+VPAP T + ++ E G++PV+L RE+ FV NR+Q A++ E
Sbjct: 146 PLVEVVPAPATSSDTVERALEFYRSCGREPVALNREVRGFVGNRLQNALMKE 197
>UniRef50_Q7WLK3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=3; Bordetella|Rep: Putative 3-hydroxyacyl-CoA
dehydrogenase - Bordetella bronchiseptica (Alcaligenes
bronchisepticus)
Length = 313
Score = 69.3 bits (162), Expect = 1e-10
Identities = 43/148 (29%), Positives = 72/148 (48%), Gaps = 1/148 (0%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
+ ++G G+IG SWA++FA G +VT+ + A + + + E L G +
Sbjct: 4 VAVIGGGIIGASWAVVFARRGLEVTIVERDAACLAGLPARLAGMI---ERSASLLGAGEQ 60
Query: 301 SEQFQCIKGSTD-LETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 477
G+TD L AV A +VQE V ENL LK+ +F LD++ + +
Sbjct: 61 PGDVAARIGATDALAAAVGRADYVQEAVSENLALKRTLFAELDALAPAHALLASSTSTYG 120
Query: 478 XXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
E L +++ +V+HP+ PP+ P+
Sbjct: 121 ASQFTEALAGRARCLVAHPMTPPHLSPV 148
Score = 54.8 bits (126), Expect = 3e-06
Identities = 24/55 (43%), Positives = 35/55 (63%)
Frame = +2
Query: 557 PLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEVWR 721
P+VE+ + WT P+V M +GQ PV + +EI FVLNR+Q A+L E++R
Sbjct: 147 PVVEMAASAWTDPQVLAGAEAFMRSLGQHPVRIRKEIPGFVLNRLQGALLMEMFR 201
>UniRef50_Q24N80 Cluster: Putative uncharacterized protein; n=1;
Desulfitobacterium hafniense Y51|Rep: Putative
uncharacterized protein - Desulfitobacterium hafniense
(strain Y51)
Length = 313
Score = 69.3 bits (162), Expect = 1e-10
Identities = 45/152 (29%), Positives = 73/152 (48%)
Frame = +1
Query: 106 FKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLR 285
F++ K+ +VG+G++G A L+A G+QV +YD +Q+ A + I + L +GL
Sbjct: 2 FENWKLLVVGAGVMGSGIAQLYACKGFQVALYDKFPEQLDRAKQLIANNMENLIKEGLAT 61
Query: 286 GELKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXX 465
E +A I T+LE A V E V EN D+K++ F LD + + I
Sbjct: 62 QE-EAERTKTLISYETELEKCAPQADLVLESVFENADVKRETFAQLDKLCASDCILCSNT 120
Query: 466 XXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
+ H + I++H NPP+ + L
Sbjct: 121 SASNIFEIAP-VSHPERQIITHYFNPPFIMDL 151
>UniRef50_O29077 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyacyl-CoA dehydrogenase
- Archaeoglobus fulgidus
Length = 295
Score = 69.3 bits (162), Expect = 1e-10
Identities = 49/144 (34%), Positives = 68/144 (47%), Gaps = 3/144 (2%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDV---VAKQITDAIEDIKYQLHTLENDGLLRGE 291
IG+VG+G++G A + A GY V + DV V K+ + IE + L L G + E
Sbjct: 9 IGVVGAGVMGHGIAQVAARTGYDVVMVDVSEEVLKKAMELIESGPFGLRRLVEKGKM-SE 67
Query: 292 LKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 471
+A I+ ST LE A+K A F+ E V E DLKKK+F LD + TI
Sbjct: 68 DEAKAVMARIRTSTSLE-ALKDADFIIEAVTEKADLKKKIFAELDRICKPETIIASNTSA 126
Query: 472 XXXXXXXEGLKHKSQVIVSHPVNP 543
++ K + I H NP
Sbjct: 127 IMISDLATAVERKDKFIGMHWFNP 150
>UniRef50_Q39HR3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=24;
Burkholderia|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 305
Score = 68.9 bits (161), Expect = 2e-10
Identities = 49/149 (32%), Positives = 74/149 (49%), Gaps = 1/149 (0%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 297
+I IVG+G+IG SWA + + G+ DVVA TD +L E+ GE +
Sbjct: 5 RIAIVGAGVIGASWAAFYLTQGF-----DVVA---TDPAPQADTRLR--ESLAAFLGE-R 53
Query: 298 ASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNT-IXXXXXXXX 474
A+E + DL A+ G FVQE PE LDLK+ +++ +D V+ + I
Sbjct: 54 AAELSARLSFDADLVRALDGVDFVQENGPERLDLKRALYRQMDDVLPAHVPIASSSSGLK 113
Query: 475 XXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
KH + +++HP NPP+ +PL
Sbjct: 114 MSDIQTACDKHPERCLIAHPFNPPHLIPL 142
Score = 39.9 bits (89), Expect = 0.085
Identities = 20/59 (33%), Positives = 34/59 (57%)
Frame = +2
Query: 542 HLITYPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEVW 718
HLI PLVE+V T +V + ++ + +G+Q + L +E+ V NR+ A+ EV+
Sbjct: 138 HLI--PLVELVGGDATSQDVTARVKDFYDALGKQTIVLNKEMTGHVANRLAAALFREVY 194
>UniRef50_Q396V2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=9;
Bacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 317
Score = 68.9 bits (161), Expect = 2e-10
Identities = 43/150 (28%), Positives = 68/150 (45%), Gaps = 1/150 (0%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
+++ ++G+G+IG SWA LF + G V DV + + LE GL
Sbjct: 6 KRVAVIGTGVIGASWAALFLAKGLDVAATDVAPDAEARLRQYLDAAWPALEELGLAPAAS 65
Query: 295 KASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 474
+A F + DL AV GA VQE PE +D K+ ++ LD+++ +
Sbjct: 66 RARLTF-----THDLAEAVAGAGLVQENGPERIDFKRTLYGQLDALLPPDVPIASSSSGL 120
Query: 475 XXXXXXEGL-KHKSQVIVSHPVNPPYYVPL 561
G H + ++ HP NPP+ +PL
Sbjct: 121 TMSEIQTGCPAHPERCVIGHPFNPPHLIPL 150
Score = 38.3 bits (85), Expect = 0.26
Identities = 21/58 (36%), Positives = 31/58 (53%)
Frame = +2
Query: 542 HLITYPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEV 715
HLI PLVEIV T + +K +G++ + L +E+ V NR+Q A+ EV
Sbjct: 146 HLI--PLVEIVSGAQTSEQTVEKVTAFYTSLGKRTIRLHKEVPGHVANRLQAALWREV 201
>UniRef50_Q2J5F5 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=3; Actinomycetales|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Frankia sp. (strain CcI3)
Length = 323
Score = 68.5 bits (160), Expect = 2e-10
Identities = 42/148 (28%), Positives = 67/148 (45%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 297
++ ++G+G IG W LF + GY+V V + IE + + L GL
Sbjct: 11 RVAVIGAGSIGLGWITLFLAHGYRVRVNSTRSN-----IETVIHDALRLFTPGLPGASRD 65
Query: 298 ASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 477
++ ++ DLE AV VQE PENL++K+ +F L+ T+
Sbjct: 66 PADLAGRLEIEPDLERAVADVAVVQENTPENLEIKQDLFARLEKHAAAGTLLLSSTSTML 125
Query: 478 XXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
+ + S +IV HP NPP+ +PL
Sbjct: 126 PADLGARMDNPSHLIVGHPFNPPHVIPL 153
Score = 41.5 bits (93), Expect = 0.028
Identities = 20/52 (38%), Positives = 27/52 (51%)
Frame = +2
Query: 557 PLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDE 712
PLVE+V + P+ E +G+ PV L R I F NR+Q A+L E
Sbjct: 152 PLVEVVGDTTSDPDAVSAAAEFYRSVGKTPVVLRRPIAAFAANRLQSALLQE 203
>UniRef50_Q5L0D2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Geobacillus kaustophilus
Length = 281
Score = 68.1 bits (159), Expect = 3e-10
Identities = 46/144 (31%), Positives = 63/144 (43%)
Frame = +1
Query: 112 SEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGE 291
+E I ++G+G++G A A VG V +YDV + + + + L G L E
Sbjct: 2 AETIAVIGAGVMGSGIAQTAAMVGKTVYLYDVSEAALQNGLASAEKSLRRFVKTGGL-SE 60
Query: 292 LKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 471
+A I+ + DL AV+GA V E VPENL LKK VFQ LD + + I
Sbjct: 61 PEARAALGRIRSTVDLAEAVRGADVVIEAVPENLALKKDVFQQLDQLAKPDAILATNTSE 120
Query: 472 XXXXXXXEGLKHKSQVIVSHPVNP 543
VI H NP
Sbjct: 121 LSVTALAAATNRPENVIGMHWFNP 144
>UniRef50_O28011 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 668
Score = 68.1 bits (159), Expect = 3e-10
Identities = 45/162 (27%), Positives = 75/162 (46%)
Frame = +1
Query: 76 VASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQL 255
V + M + + + + ++G+GL+G A + A GY VT+ D+ + + + IK L
Sbjct: 5 VKQVINMDVRERIKTVAVLGAGLMGHGIAEVCAMAGYNVTMRDIKQEFVDRGMNMIKESL 64
Query: 256 HTLENDGLLRGELKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVV 435
LE G ++ A E IK + DLE AVK A V E VPE +++KK+V++ +D +
Sbjct: 65 AKLEQKGKIKS---AEEVLSRIKPTVDLEEAVKDADLVIEAVPEVVEIKKQVWEEVDKLA 121
Query: 436 DDNTIXXXXXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
+ I + + H NPP + L
Sbjct: 122 KPDCIFTSNTSTMRITMLADFTSRPEKFAGLHFFNPPVLMRL 163
>UniRef50_A6CP14 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Bacillus sp. SG-1|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Bacillus sp. SG-1
Length = 293
Score = 67.7 bits (158), Expect = 4e-10
Identities = 44/152 (28%), Positives = 73/152 (48%), Gaps = 3/152 (1%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
+K+ ++GSG++GR A + A G+Q T+ DV +Q+ A + +L ++ G+ RG+L
Sbjct: 13 DKLVVIGSGVMGRGIAYVSAVGGFQTTLVDVEQRQLDSA----QGELTSIFQKGVDRGKL 68
Query: 295 KASEQFQC---IKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXX 465
E + STD+ AV+ A V E VPE ++KK VF+ +D ++
Sbjct: 69 SKEESTDAQGRLSFSTDMAKAVESADLVIEAVPEKTEIKKAVFEKIDEYAQESCYFATNT 128
Query: 466 XXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
+VI H NP + +PL
Sbjct: 129 STMSPTEIASFTGRPKKVIAMHFFNPVHKMPL 160
>UniRef50_Q5LPZ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=5; Bacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Silicibacter pomeroyi
Length = 317
Score = 66.9 bits (156), Expect = 6e-10
Identities = 44/150 (29%), Positives = 70/150 (46%), Gaps = 2/150 (1%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVY--DVVAKQITDAIEDIKYQLHTLENDGLLRGE 291
++ +G G IG WA F + GY VT Y D + I D + +L GL G
Sbjct: 11 RVTSIGGGPIGGGWAAHFLARGYDVTSYLHDRAEEGAFRTILDTAWI--SLTALGLAPGA 68
Query: 292 LKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 471
+ ++ + + DL+ AV GA F+QE PENL +K+ ++ L +V +N +
Sbjct: 69 --SLDRLRVVH---DLDAAVAGAGFIQESAPENLAMKQALYHRLGRIVPENVVIGSSTSG 123
Query: 472 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
+ + ++ HP NPPY +PL
Sbjct: 124 LMMTDIQANCETPGRTVIGHPFNPPYLLPL 153
Score = 35.5 bits (78), Expect = 1.8
Identities = 19/52 (36%), Positives = 26/52 (50%)
Frame = +2
Query: 557 PLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDE 712
PLVEIV T P + E G+ P+ + +EI FV R+Q A+ E
Sbjct: 152 PLVEIVGGERTDPAAVEWAGEFYRVAGKAPLMMKKEIPGFVATRLQEALWRE 203
>UniRef50_Q73Q34 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
n=1; Treponema denticola|Rep: 3-hydroxyacyl-CoA
dehydrogenase, putative - Treponema denticola
Length = 309
Score = 66.5 bits (155), Expect = 9e-10
Identities = 44/156 (28%), Positives = 73/156 (46%)
Frame = +1
Query: 94 MASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLEND 273
M K K K+ +VG G +G + +FA G+ V + + + A++ IK L+ +
Sbjct: 1 MIEKGKKIKVAVVGDGTMGHGISEVFAKAGHTVQIIGLNDASLKSALDRIKLSLNEFVAE 60
Query: 274 GLLRGELKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIX 453
GL+ I STD++ A AI + E +PEN+DLK + F L+ + +TI
Sbjct: 61 GLVSAS-DIDTIVGRISFSTDIQKAEDAAIVI-EALPENMDLKTETFGKLEKICPQDTIL 118
Query: 454 XXXXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
+ +K + +VI +H PP +PL
Sbjct: 119 ATASGHSVSEVIAQ-VKKRDRVIATHFWFPPQLLPL 153
Score = 54.4 bits (125), Expect = 4e-06
Identities = 25/54 (46%), Positives = 35/54 (64%)
Frame = +2
Query: 557 PLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEVW 718
PLVE+ AP T T E+++ IG++PV + +EID F+ NRIQ+A L E W
Sbjct: 152 PLVEVCGAPETSKATIDTTCELLKGIGKKPVVIDKEIDGFIGNRIQFAALREAW 205
>UniRef50_A1FNB9 Cluster: 3-hydroxyacyl-CoA dehydrogenase precursor;
n=4; Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase
precursor - Pseudomonas putida W619
Length = 313
Score = 66.1 bits (154), Expect = 1e-09
Identities = 44/147 (29%), Positives = 75/147 (51%), Gaps = 2/147 (1%)
Frame = +1
Query: 127 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASE 306
++G+GL+G A +FA G++V++YD A + A + + H L+ G+ + A+
Sbjct: 9 VIGAGLMGHGIAQVFAQAGHKVSLYDPDAATLDLAPQRVA---HNLDQMGIASAPILAN- 64
Query: 307 QFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXX 486
I TDL AV A V E VPE L+LK+K+F ++ +T+
Sbjct: 65 ----IALFTDLREAVSNADIVIEAVPERLELKQKLFADIAGFAPPHTVLASNTSVIPITE 120
Query: 487 XXE--GLKHKSQVIVSHPVNPPYYVPL 561
E G + +++++ +H NPP+ VPL
Sbjct: 121 IGEMLGSEARARLVGTHWWNPPHLVPL 147
Score = 44.8 bits (101), Expect = 0.003
Identities = 21/57 (36%), Positives = 36/57 (63%)
Frame = +2
Query: 542 HLITYPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDE 712
HL+ PLVE+V T V + T E+++ +G+ PV + R++ F+ NR+Q+A+ E
Sbjct: 143 HLV--PLVEVVRTEHTSLSVFESTFELLQSLGKSPVKVNRDVAGFIGNRLQHAMWRE 197
>UniRef50_O30218 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 661
Score = 64.1 bits (149), Expect = 5e-09
Identities = 42/147 (28%), Positives = 66/147 (44%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
+ ++G+G +G + A + A G+ V + DV Q+ A+E I+ L G + +
Sbjct: 9 VAVIGAGSMGHAIAEVVAIHGFNVKLMDVSEDQLKRAMEKIEEGLRKSYERGYISED--P 66
Query: 301 SEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 480
+ + I+ + DL K A V E +PE DLKKKVF ++ D+TI
Sbjct: 67 EKVLKRIEATADLIEVAKDADLVIEAIPEIFDLKKKVFSEIEQYCPDHTIFATNTSSLSI 126
Query: 481 XXXXEGLKHKSQVIVSHPVNPPYYVPL 561
E K + I H NPP + L
Sbjct: 127 TKLAEATKRPEKFIGMHFFNPPKILKL 153
>UniRef50_UPI00005102FD Cluster: COG1250: 3-hydroxyacyl-CoA
dehydrogenase; n=1; Brevibacterium linens BL2|Rep:
COG1250: 3-hydroxyacyl-CoA dehydrogenase -
Brevibacterium linens BL2
Length = 311
Score = 63.7 bits (148), Expect = 6e-09
Identities = 46/150 (30%), Positives = 72/150 (48%), Gaps = 2/150 (1%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLH-TLENDGLLRGEL 294
K+ I+G+G+IG +WA F + G+ VT +D A ++ Q+ LE G G++
Sbjct: 6 KVAILGTGVIGAAWATGFLTAGHTVTAFD----PADGAEARLRSQVEGNLEVTG--EGDI 59
Query: 295 KASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNT-IXXXXXXX 471
++ + GS L +V A FVQE PE LD+K+ + DS V + I
Sbjct: 60 TSAMERLHFAGS--LAESVGDADFVQENGPERLDIKQSMLAETDSAVPASAIIASSTSGF 117
Query: 472 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
+ H +++V HP NP + VPL
Sbjct: 118 APSELATKATNHPERIVVGHPFNPAHLVPL 147
Score = 50.4 bits (115), Expect = 6e-05
Identities = 25/59 (42%), Positives = 36/59 (61%)
Frame = +2
Query: 542 HLITYPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEVW 718
HL+ PLVE+VP P T EV K+ EI IG++P+ + E+ V NR+Q A+ E +
Sbjct: 143 HLV--PLVELVPTPATPAEVVKRGLEIYRSIGKKPILVRAELPGHVTNRLQAALWQEAY 199
>UniRef50_Q9RZ10 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
n=11; Bacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase,
putative - Deinococcus radiodurans
Length = 347
Score = 62.9 bits (146), Expect = 1e-08
Identities = 38/117 (32%), Positives = 56/117 (47%)
Frame = +1
Query: 100 SKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGL 279
S + + + GSG++G A A G+ V +YD+ I A E + +L L
Sbjct: 50 SSMSIKTVTVCGSGVLGSQIAFQTAFHGFDVHLYDINDAAIAKARETLG-KLQARYQQDL 108
Query: 280 LRGELKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTI 450
+ + F I TD+ AVKG V E +PEN+D+K+K + L V D NTI
Sbjct: 109 KVDAQQTGDAFARISFFTDIAEAVKGVDLVIEAIPENMDIKRKFYNQLGEVADPNTI 165
>UniRef50_Q2W2Y1 Cluster: Glyoxysomal fatty acid beta-oxidation
multifunctional protein MFP-a; n=3;
Magnetospirillum|Rep: Glyoxysomal fatty acid
beta-oxidation multifunctional protein MFP-a -
Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
Length = 703
Score = 61.7 bits (143), Expect = 2e-08
Identities = 43/148 (29%), Positives = 67/148 (45%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 297
K+GI+G+G +G AM FA++G VT+ DV + + + I+ + G L E +
Sbjct: 296 KVGIIGAGTMGGGIAMCFANIGIPVTIIDVSDENLQRGLGVIRKNYERSVSRGSLTQE-Q 354
Query: 298 ASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 477
+ + STD A+K A E V E ++LKK +F LD+V+ I
Sbjct: 355 LESRMGLLSASTDY-AALKDADLAIEAVFEKMELKKDIFAKLDAVLPAGAILGTNTSTLD 413
Query: 478 XXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
K + VI H +P +PL
Sbjct: 414 IDEIANTTKRPADVIGLHFFSPANVMPL 441
>UniRef50_Q28KL8 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=2; Bacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase NAD-binding - Jannaschia sp. (strain CCS1)
Length = 466
Score = 61.7 bits (143), Expect = 2e-08
Identities = 47/152 (30%), Positives = 71/152 (46%), Gaps = 4/152 (2%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDV---VAKQITDAIEDIKYQLHTLENDGLL-R 285
K I+G G+IG WA F G+ V +YD ++I + +++ + L L + L
Sbjct: 2 KTAIIGGGVIGGGWAARFLLNGWNVAIYDPDPEAERKIGEVMDNARRALPGLYDTALPPE 61
Query: 286 GELKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXX 465
G L+ ++ DL AV A +VQE VPE LD+K KV L ++ +
Sbjct: 62 GTLRFTD---------DLGDAVGDADWVQESVPERLDIKHKVHAELTTLAPGRAVIGSST 112
Query: 466 XXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
E ++VIV+HP NP Y +PL
Sbjct: 113 SGFKPSELTE---KGARVIVAHPFNPVYLLPL 141
>UniRef50_Q988C8 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1;
Mesorhizobium loti|Rep: 3-hydroxybutyryl-coA
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 309
Score = 60.9 bits (141), Expect = 4e-08
Identities = 41/147 (27%), Positives = 64/147 (43%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
I I+G G +G A A G QV YDV AIE + L E G
Sbjct: 5 IAIIGLGTMGPGMAARLARGGLQVVAYDVAPA----AIERARSMLSVAETVLDALGIALP 60
Query: 301 SEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 480
S ++ + D+ AV GA V E VPEN+ +K V++ +D ++ +TI
Sbjct: 61 SAGVGTVRFTDDIGDAVSGADLVIENVPENISIKADVYRTIDGLIGQDTIVASDTSGIPI 120
Query: 481 XXXXEGLKHKSQVIVSHPVNPPYYVPL 561
+ + +++ H NPP+ +P+
Sbjct: 121 TKLQAHISYPERMVGMHWSNPPHIIPM 147
Score = 43.6 bits (98), Expect = 0.007
Identities = 19/57 (33%), Positives = 34/57 (59%)
Frame = +2
Query: 542 HLITYPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDE 712
H+I P++E++ T P+ R+++ IG PV + +++ FV NR+ YA+L E
Sbjct: 143 HII--PMIEVIAGEKTAPQTVATIRDLIRSIGLLPVVVKKDVPGFVENRVLYALLRE 197
>UniRef50_Q8XI27 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase
NAD-dependent; n=9; Clostridiales|Rep:
Beta-hydroxybutyryl-CoA dehydrogenase NAD-dependent -
Clostridium perfringens
Length = 282
Score = 60.9 bits (141), Expect = 4e-08
Identities = 41/143 (28%), Positives = 64/143 (44%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
EKI ++G+G +G FA GY+V V D+ + + I I L L + G + E
Sbjct: 2 EKIFVIGAGTMGAGIVQAFAQKGYEVIVRDIKDEFVDRGIAGINKGLTKLVSKGKITEED 61
Query: 295 KASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 474
K + I G+TDL A + ++ V EN+++KK++F LD + + TI
Sbjct: 62 KEA-VLSKITGTTDLGLAADCDLVIEAAV-ENMEIKKQIFAELDKICKEETILASNTSSL 119
Query: 475 XXXXXXEGLKHKSQVIVSHPVNP 543
+VI H NP
Sbjct: 120 SITEVASATNRPDRVIGMHFFNP 142
>UniRef50_Q7WCB1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
Bordetella|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Bordetella parapertussis
Length = 354
Score = 60.5 bits (140), Expect = 6e-08
Identities = 40/149 (26%), Positives = 67/149 (44%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
+ + +VG+G +G A LFAS G+ V + D +A +T A + I+ QL D +
Sbjct: 50 QNLAVVGAGAMGSGIAALFASKGFDVVLIDPMAGALTRAAQVIERQLGVYAPDAI----- 104
Query: 295 KASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 474
+ Q I+ LE A + + E VPE L LK+ +F LD++ D I
Sbjct: 105 --APAMQRIRMDAGLEAACSAQLVI-EAVPEKLALKRDIFARLDTLCDPQAIFATNTSGL 161
Query: 475 XXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
+ + + + + +H P +PL
Sbjct: 162 SINDIAQAVTRRDRFVGTHFFTPADVIPL 190
Score = 36.7 bits (81), Expect = 0.79
Identities = 17/52 (32%), Positives = 30/52 (57%)
Frame = +2
Query: 557 PLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDE 712
PLVE+V T + + ++ G++PV + ++I F+ NRIQ+A+ E
Sbjct: 189 PLVEVVRNDDTSEQTVARVMGMLRAGGKRPVLVRKDIPGFIANRIQHALARE 240
>UniRef50_Q5V0V6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Halobacteriaceae|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Haloarcula marismortui (Halobacterium marismortui)
Length = 654
Score = 60.5 bits (140), Expect = 6e-08
Identities = 37/147 (25%), Positives = 66/147 (44%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
+ ++G+G +G A + A GY V + D+ A + D ++I++ L L G L +
Sbjct: 11 VAVLGAGTMGHGIAEVAAIAGYDVVLRDIDAAIVEDGYDEIEWSLEKLAEKGRL--DEDP 68
Query: 301 SEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 480
+ + +TDLE AV A V E PE L +K+ +F+++D+ + +
Sbjct: 69 DDVAARVATTTDLEAAVSDADLVIEAGPEQLSVKQDIFESVDAAAPADALLATNSSSLSI 128
Query: 481 XXXXEGLKHKSQVIVSHPVNPPYYVPL 561
+ V+ H NPP + L
Sbjct: 129 TEIAAATERPESVLGLHFFNPPVKMDL 155
>UniRef50_Q11E57 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=1; Mesorhizobium sp. BNC1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Mesorhizobium sp. (strain BNC1)
Length = 485
Score = 60.1 bits (139), Expect = 7e-08
Identities = 38/141 (26%), Positives = 68/141 (48%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
IG++G+G +G A + A+ G++V ++DV + +E +L TL G + + +A
Sbjct: 11 IGVIGAGTMGAGIAQVAAAAGHKVLLFDVASGAAASGLERTAKELATLVKRGKME-QKRA 69
Query: 301 SEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 480
E I + LE A+ V E + E LD+K+KVF L++++ ++ I
Sbjct: 70 EEIIGRITIAEKLEDLAPAALTV-EAIVERLDVKQKVFAQLEAILAEDAILATNTSSISI 128
Query: 481 XXXXEGLKHKSQVIVSHPVNP 543
LK +++ H NP
Sbjct: 129 TAIGAALKRPERLVGMHFFNP 149
>UniRef50_A1CC71 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
n=2; Aspergillus|Rep: 3-hydroxyacyl-CoA dehydrogenase,
putative - Aspergillus clavatus
Length = 307
Score = 58.8 bits (136), Expect = 2e-07
Identities = 41/144 (28%), Positives = 69/144 (47%), Gaps = 2/144 (1%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDG--LLRGEL 294
+ ++G G++GR M++A+ G+ V +Y+ K A+ +KY L LL G+
Sbjct: 16 VAVIGGGVLGRRLCMMWAAAGHTVQLYE---KSPEVAVAALKYIHEALPQQASKLLLGK- 71
Query: 295 KASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 474
KA + ++ LETAV+ A V E +PE L LK ++F LD + + I
Sbjct: 72 KAGHGIGHVSPASSLETAVQNAWMVIEAIPELLPLKIELFGQLDQLAPADCILATNSSSY 131
Query: 475 XXXXXXEGLKHKSQVIVSHPVNPP 546
E + +++V +H PP
Sbjct: 132 KSREMLEKVARRARVCNAHYYMPP 155
>UniRef50_Q5UWD9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyacyl-CoA dehydrogenase
- Haloarcula marismortui (Halobacterium marismortui)
Length = 295
Score = 58.8 bits (136), Expect = 2e-07
Identities = 42/150 (28%), Positives = 68/150 (45%), Gaps = 3/150 (2%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG---E 291
+ I+G+G +G A + A G+ V++ D+ A + D + I+ L +G+ R E
Sbjct: 4 VAILGAGTMGHGIAQVSAMAGHDVSLRDIEADIVDDGLTAIESNLE----EGIAREKVTE 59
Query: 292 LKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 471
A +KG+T LE AV GA V E VPE + +K + ++S VD T+
Sbjct: 60 STAEATIDRLKGTTSLEEAVTGADLVVEAVPEEMAIKHETLTAVESHVDPATLIASNTSS 119
Query: 472 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
L + + I H NP + + L
Sbjct: 120 LSLTEIASVLDYPERAIGLHFFNPVHIMAL 149
>UniRef50_A1IEK7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Candidatus
Desulfococcus oleovorans Hxd3
Length = 387
Score = 58.4 bits (135), Expect = 2e-07
Identities = 36/105 (34%), Positives = 54/105 (51%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
+KI ++GSG +G A + GY V + DV + + + ++ +K + L G L E
Sbjct: 7 KKIAVIGSGAMGHGIAQVCIMAGYTVVMVDVKQEFLDNGMKKVKESMDFLVGKGKLSAED 66
Query: 295 KASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDS 429
K Q + S D + AV V E VPE +DLKKKVF ++ S
Sbjct: 67 KDRMMGQ-LSTSLDNKAAVADVQVVIEAVPEIMDLKKKVFADVSS 110
>UniRef50_Q0C7S2 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 589
Score = 58.4 bits (135), Expect = 2e-07
Identities = 37/116 (31%), Positives = 58/116 (50%), Gaps = 1/116 (0%)
Frame = +1
Query: 106 FKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIK-YQLHTLENDGLL 282
++ + I+G+G++GR A ++AS GY V V D +Q D + +K + + E+ G
Sbjct: 11 YRERPVAILGAGVLGRRIACIWASAGYDVQVRDPSPEQRADCVAYVKQHVVAYAEHTGAA 70
Query: 283 RGELKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTI 450
GE+ SE DL+ V A V E VPE + LK F+ LD + + I
Sbjct: 71 PGEVTTSE---------DLKNTVNNAWLVIEAVPEKIQLKIDTFEQLDKLAPTDCI 117
>UniRef50_UPI000023E2B1 Cluster: hypothetical protein FG00090.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG00090.1 - Gibberella zeae PH-1
Length = 320
Score = 58.0 bits (134), Expect = 3e-07
Identities = 41/149 (27%), Positives = 67/149 (44%), Gaps = 2/149 (1%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL-K 297
+ IVG G+IG WA+LF S G +V +++ A E +K L + RG K
Sbjct: 8 VAIVGCGVIGMGWAVLFMSCGLKV----IISDPADGAHESLKRYLEQARSFFEERGNFDK 63
Query: 298 ASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDN-TIXXXXXXXX 474
S ++ + D+ + FVQE PE ++ K+ + + LD I
Sbjct: 64 LSSNYEFV---DDILPLLPEVDFVQENGPERVEFKQSLMEKLDENTRPGVAIASSSSGLP 120
Query: 475 XXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
+ K S++++ HP NPP+ +PL
Sbjct: 121 SSAFIQKCKKDPSRILIGHPFNPPHLIPL 149
Score = 48.8 bits (111), Expect = 2e-04
Identities = 24/59 (40%), Positives = 36/59 (61%)
Frame = +2
Query: 542 HLITYPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEVW 718
HLI PLVE+VP P T +V + +G++P+ L +E+ FV NR+Q AI +E +
Sbjct: 145 HLI--PLVEVVPHPGTSSDVVSSALAFYKSLGKKPILLHQEVPGFVSNRLQAAINNEAY 201
>UniRef50_Q5HKI5 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=3; Staphylococcus|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Staphylococcus
epidermidis (strain ATCC 35984 / RP62A)
Length = 321
Score = 57.6 bits (133), Expect = 4e-07
Identities = 38/148 (25%), Positives = 60/148 (40%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 297
K +VG+G+IG W + G++V D + +K E GL
Sbjct: 2 KFAVVGTGVIGSGWITRMLAHGHEVIATDPSEGAYERMLTQVKQNWPYAEQMGLAE---- 57
Query: 298 ASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 477
+ Q + + LE AVK A +QE VPE ++K V + +D
Sbjct: 58 -NASIQNLTFTPHLEEAVKDADHIQENVPEVEEIKDAVLKEIDFYAKPEATIGSSTSGIM 116
Query: 478 XXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
L H +++V+HP +P Y +PL
Sbjct: 117 PSELQANLSHPERLVVAHPFHPVYILPL 144
Score = 38.7 bits (86), Expect = 0.20
Identities = 19/52 (36%), Positives = 27/52 (51%)
Frame = +2
Query: 557 PLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDE 712
PLVEIVP T E K +I E IG + + EI+ + +R+ A+ E
Sbjct: 143 PLVEIVPGKQTSEETTVKAEQIYESIGMDVLHVRHEIEGHIADRLMEALWRE 194
>UniRef50_A5D5N2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Pelotomaculum thermopropionicum SI|Rep:
3-hydroxyacyl-CoA dehydrogenase - Pelotomaculum
thermopropionicum SI
Length = 319
Score = 57.6 bits (133), Expect = 4e-07
Identities = 39/147 (26%), Positives = 60/147 (40%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
+ I+G+G +G S A G V + DV A + A I+ L + G +G
Sbjct: 7 LAIIGAGTMGHSIAAAALQHGVSVRLIDVSAPALETARRKIQSYLASAAGKGGGKGGAVP 66
Query: 301 SEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 480
++ ++ V GA V E VPE LDLKK++F LD + + I
Sbjct: 67 GHLAGVLETCMEMAAGVTGADMVIEAVPEKLDLKKEIFAQLDKLCPPSVILATNTSGLPI 126
Query: 481 XXXXEGLKHKSQVIVSHPVNPPYYVPL 561
+V+ +H P Y +PL
Sbjct: 127 TAIASAAARPERVLGTHFYMPAYLIPL 153
Score = 49.2 bits (112), Expect = 1e-04
Identities = 22/52 (42%), Positives = 36/52 (69%)
Frame = +2
Query: 557 PLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDE 712
PLVE+V + +T P+VA T ++ IG++PV + ++I F+ NR+Q+AI E
Sbjct: 152 PLVEVVCSDYTSPDVAGDTVAFLQSIGRKPVLVKKDIPGFIGNRLQHAIARE 203
>UniRef50_Q5V357 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
Halobacteriaceae|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Haloarcula marismortui (Halobacterium marismortui)
Length = 669
Score = 57.6 bits (133), Expect = 4e-07
Identities = 39/150 (26%), Positives = 67/150 (44%), Gaps = 1/150 (0%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTL-ENDGLLRGE 291
+ I ++G+G +G + A GY V + D+ + + D ++I++ L+ L E D L + E
Sbjct: 22 DTIAVLGAGNMGHGITEVAALAGYDVRMRDIKDEFVEDGYDNIEWSLNKLAERDQLTQEE 81
Query: 292 LKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 471
A+ + D+E AV V E VPE +++KK V+ ++ +N I
Sbjct: 82 ADAA--LDRVTPLVDVEEAVSDVDVVIEAVPEKMEIKKDVYTEVEEHAPENAIFATNTSS 139
Query: 472 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
E + Q H NPP + L
Sbjct: 140 LSITELSEVTERPEQFCGMHFFNPPVRMQL 169
>UniRef50_Q2B4D1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Firmicutes|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Bacillus sp. NRRL B-14911
Length = 295
Score = 57.2 bits (132), Expect = 5e-07
Identities = 34/112 (30%), Positives = 60/112 (53%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
+ I +VG+G +G AML A G++ T++D+ K + A E ++ + G L E
Sbjct: 8 KNITVVGAGQMGHQIAMLCALGGFETTLHDMQEKALDQAQEKLRGIMDKWAAKGKLPSE- 66
Query: 295 KASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTI 450
+ F ++ ++D AVK A F+ E V E L++K++VF L+ + + I
Sbjct: 67 QIEAAFSRLRCTSDFGEAVKSADFIIEAVVEKLEVKREVFSMLEEMAPPHAI 118
>UniRef50_A2TU34 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
Flavobacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Dokdonia donghaensis MED134
Length = 394
Score = 57.2 bits (132), Expect = 5e-07
Identities = 42/145 (28%), Positives = 69/145 (47%), Gaps = 2/145 (1%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
+ IGI+G+G +G A + A+ G V ++DV + + A E ++ L L + +G +
Sbjct: 3 KNIGIIGAGTMGSGIAQVAATAGCAVKLFDVNQEALDKAKEALEKVLKRL----IEKGRI 58
Query: 295 KASEQFQCIKGSTDLETA--VKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXX 468
ASE+ + T + T + A E + ENL++KKKVFQ L++ V D I
Sbjct: 59 DASEKDRIQANITYVTTLKELANADLTIEAIVENLEVKKKVFQELETYVSDTAIIASNTS 118
Query: 469 XXXXXXXXEGLKHKSQVIVSHPVNP 543
L++ + I H NP
Sbjct: 119 SLSIASIAASLQNPERCIGIHFFNP 143
>UniRef50_Q0UZL9 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 308
Score = 57.2 bits (132), Expect = 5e-07
Identities = 41/150 (27%), Positives = 77/150 (51%), Gaps = 2/150 (1%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAML-FASVG-YQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGE 291
K+ ++G+G IG S+A A + Q+T+YD ++ IE+ L G +
Sbjct: 7 KVTLIGTGTIGLSFAAFHLAKLSPSQLTIYDT-RSDLSTYIEEF---LPKFFESGKSPAD 62
Query: 292 LKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 471
L SE I+ + L+ AV + +QE PENLD+K+K+++ ++ ++ +
Sbjct: 63 L--SE----IRLAVTLQEAVSDSHIIQESGPENLDVKRKLWKEVEKYAPNDALLWSSTSG 116
Query: 472 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
+ ++ K++++V HP NPP+ +PL
Sbjct: 117 IPASQQAQDMQDKTRLLVVHPYNPPHIMPL 146
Score = 45.6 bits (103), Expect = 0.002
Identities = 20/52 (38%), Positives = 32/52 (61%)
Frame = +2
Query: 557 PLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDE 712
PL+E+VP+ T V +T++ E G+ P+ + RE FV NR+ +A+L E
Sbjct: 145 PLLELVPSSETSDTVISRTQDFWRERGRVPIHIKRETTGFVANRLAFALLRE 196
>UniRef50_Q4J598 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD
binding domain; n=2; Azotobacter vinelandii|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD binding domain -
Azotobacter vinelandii AvOP
Length = 208
Score = 56.8 bits (131), Expect = 7e-07
Identities = 38/147 (25%), Positives = 72/147 (48%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
I I+GSG +G A A G++V + +Q+ + + + L L G E A
Sbjct: 6 IAILGSGSMGVGIATHLARHGHEVLLIYPSMEQLAEVLAMARSILAGLVEAGRFAPEQVA 65
Query: 301 SEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 480
+ + ++ ST L+ V G + E +PE ++LK+ ++ L+ +VD +
Sbjct: 66 ATLAR-LRTSTRLKD-VAGVRLLIETLPERIELKRALYAELERIVDAEAVIASDTGGLSP 123
Query: 481 XXXXEGLKHKSQVIVSHPVNPPYYVPL 561
EG++H +++++H +PP+ VPL
Sbjct: 124 ERLAEGMRHPGRLLIAHFRSPPHRVPL 150
>UniRef50_A5V325 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Sphingomonas wittichii RW1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Sphingomonas wittichii RW1
Length = 322
Score = 56.8 bits (131), Expect = 7e-07
Identities = 36/147 (24%), Positives = 60/147 (40%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
+ +G G+IG W F G V ++D + + GL R +
Sbjct: 13 VAAIGGGVIGGGWVAAFLGSGRAVRLHDPAPGAEARIRAHVTQAWPQMAALGLARAD--- 69
Query: 301 SEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 480
+ + +E AV+G FVQE PE D+K+ +F LD +V + +
Sbjct: 70 DDWTGRLSFHETIEDAVEGTDFVQENTPERSDVKRALFAELDRLVPADVLVGSSTSSLPI 129
Query: 481 XXXXEGLKHKSQVIVSHPVNPPYYVPL 561
GL ++ ++ HP NP + +PL
Sbjct: 130 SDLQAGLSTAARFVLGHPFNPVHLIPL 156
Score = 33.9 bits (74), Expect = 5.6
Identities = 20/61 (32%), Positives = 29/61 (47%)
Frame = +2
Query: 539 IHLITYPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEVW 718
+HLI PLVE+ T P +G++PV L RE+ + NR+ A+ E
Sbjct: 151 VHLI--PLVEVGGGDATDPAAVDTALAFYAALGKEPVRLNREVFGHIGNRLTSAMFREAV 208
Query: 719 R 721
R
Sbjct: 209 R 209
>UniRef50_A0PRD1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase FadB3;
n=1; Mycobacterium ulcerans Agy99|Rep:
3-hydroxybutyryl-CoA dehydrogenase FadB3 - Mycobacterium
ulcerans (strain Agy99)
Length = 294
Score = 56.8 bits (131), Expect = 7e-07
Identities = 39/148 (26%), Positives = 69/148 (46%)
Frame = +1
Query: 109 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG 288
+S + ++G+G +GR A++FAS G V +Y A+Q A + + L L D G
Sbjct: 13 RSRPVAVIGAGTLGRRIALMFASRGGTVRIYARRAEQRAQATQYVADNLPKLLQDRGF-G 71
Query: 289 ELKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXX 468
E+ + C L TA++GA E VPE L++K ++ +D +TI
Sbjct: 72 EVGSVTATDC------LATALEGAWLAVESVPEKLEIKTALWGQIDQAAPPDTIFATNSS 125
Query: 469 XXXXXXXXEGLKHKSQVIVSHPVNPPYY 552
+ ++ K+++ +H PP +
Sbjct: 126 SFPSRLMADNVRDKTRLCNTHFYMPPQF 153
>UniRef50_A0GEI2 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Burkholderia|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Burkholderia phytofirmans
PsJN
Length = 317
Score = 56.8 bits (131), Expect = 7e-07
Identities = 41/154 (26%), Positives = 73/154 (47%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
IG+VG+GL+G A A G++ V+DV ++ + L L + G + K
Sbjct: 19 IGVVGTGLMGVGIATQSALHGHRTIVHDVDPARLASVAPKAQAVLDELIDAGRIDPAAKQ 78
Query: 301 SEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 480
+ + I+ +L+ + A FV E +PE L+LK +++ L ++ D+ I
Sbjct: 79 AALAR-IETHAELD-VMASAQFVIEAIPEVLELKHRLYAALTQLLADDAILASNTSGFHP 136
Query: 481 XXXXEGLKHKSQVIVSHPVNPPYYVPLG*NCPST 582
L+ K + +++H NPP+ +PL P T
Sbjct: 137 DQLAAPLRAKDRFVIAHFWNPPHMIPLVEVVPGT 170
Score = 56.0 bits (129), Expect = 1e-06
Identities = 28/57 (49%), Positives = 38/57 (66%)
Frame = +2
Query: 542 HLITYPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDE 712
H+I PLVE+VP T PEV ++T +M IG +PV L + I FV NR+Q+A+L E
Sbjct: 159 HMI--PLVEVVPGTATAPEVTQQTAALMSAIGMEPVVLAKAIPGFVGNRLQFAMLRE 213
>UniRef50_Q9HRI4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7;
cellular organisms|Rep: 3-hydroxyacyl-CoA dehydrogenase
- Halobacterium salinarium (Halobacterium halobium)
Length = 286
Score = 56.8 bits (131), Expect = 7e-07
Identities = 38/151 (25%), Positives = 70/151 (46%), Gaps = 1/151 (0%)
Frame = +1
Query: 94 MASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQL-HTLEN 270
M S +E IG+VG+G +G A + A+ GY V + D+ + + + I+ L + N
Sbjct: 1 MRSLADTETIGVVGAGTMGAGIAQVAATAGYTVVMRDIEQEYVDAGFDSIESSLDRFVSN 60
Query: 271 DGLLRGELKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTI 450
D L E A I G+TDL + ++ V E++++K+ +F++LD + ++ +
Sbjct: 61 DDL--SEADADAIVDRITGTTDLAELADCDVVIEAAV-EDMEIKQDIFRDLDDALPEDVV 117
Query: 451 XXXXXXXXXXXXXXEGLKHKSQVIVSHPVNP 543
S+V+ H +NP
Sbjct: 118 LATNTSTLSITTIASVTDRASRVVGLHFMNP 148
>UniRef50_A0RUN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase; n=4; Crenarchaeota|Rep: 3-hydroxyacyl-CoA
dehydrogenase/enoyl-CoA hydratase - Cenarchaeum
symbiosum
Length = 365
Score = 56.8 bits (131), Expect = 7e-07
Identities = 37/139 (26%), Positives = 62/139 (44%)
Frame = +1
Query: 145 IGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASEQFQCIK 324
+G A + A+ GY+V + D+ + + A+E I++ L + + G + E K I+
Sbjct: 1 MGHGIAQVSAASGYEVVLRDIEQRFLDSAMEKIRWSLDKMASKGRITAEEKDGI-LNRIR 59
Query: 325 GSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXXEGLK 504
L A++GA V E VPE +DLK+KV+ LD+ + +
Sbjct: 60 PVVALGEALEGADLVIEAVPEVMDLKRKVYAELDAAAPEGAAFASNTSTLPITEIAQATS 119
Query: 505 HKSQVIVSHPVNPPYYVPL 561
+ I H NPP + L
Sbjct: 120 RPERFIGIHFFNPPQLMKL 138
Score = 39.5 bits (88), Expect = 0.11
Identities = 16/51 (31%), Positives = 30/51 (58%)
Frame = +2
Query: 560 LVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDE 712
LVE++P T E + T E +E +G+Q V +++ F++NR+ ++ E
Sbjct: 138 LVEVIPGEGTSDETTRMTLEYVESLGKQAVLCRKDVPGFIVNRLFIPMVHE 188
>UniRef50_P76083 Cluster: Probable 3-hydroxybutyryl-CoA
dehydrogenase; n=8; Enterobacteriaceae|Rep: Probable
3-hydroxybutyryl-CoA dehydrogenase - Escherichia coli
(strain K12)
Length = 475
Score = 56.8 bits (131), Expect = 7e-07
Identities = 40/143 (27%), Positives = 66/143 (46%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
+ + ++GSG +G A + AS G+QV +YD+ A+ +T AI+ I +L++ G L E
Sbjct: 6 QTVAVIGSGTMGAGIAEVAASHGHQVLLYDISAEALTRAIDGIHARLNSRVTRGKLTAE- 64
Query: 295 KASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 474
+ + TD+ A+ A V E E L++KK +F L V T+
Sbjct: 65 TCERTLKRLIPVTDIH-ALAAADLVIEAASERLEVKKALFAQLAEVCPPQTLLTTNTSSI 123
Query: 475 XXXXXXEGLKHKSQVIVSHPVNP 543
+K+ +V H NP
Sbjct: 124 SITAIAAEIKNPERVAGLHFFNP 146
>UniRef50_Q9KBD3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=8;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Bacillus halodurans
Length = 287
Score = 56.0 bits (129), Expect = 1e-06
Identities = 42/151 (27%), Positives = 71/151 (47%), Gaps = 4/151 (2%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQ-LHTLENDGLLRGELK 297
+G+VG+G +G A L A G QV + D+ Q+ DI +Q ++T + +G++
Sbjct: 6 VGVVGAGTMGSGIANLAAMSGLQVVLLDLDDNQL-----DIAWQKINTFMEKSVAKGKMS 60
Query: 298 ASEQFQC---IKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXX 468
+E+ IK +T E + + + E V ENLD+KK+VF LD+ + ++TI
Sbjct: 61 EAEKEAALGRIKSTTTYEELAEADLVI-EAVIENLDVKKEVFHTLDTCLANDTIIATNTS 119
Query: 469 XXXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
+V+ H NP + L
Sbjct: 120 SMSITEIAAATNRPDRVVGMHFFNPAQLMKL 150
>UniRef50_A4ALU9 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like
protein; n=1; marine actinobacterium PHSC20C1|Rep:
3-hydroxyacyl-CoA dehydrogenase-like protein - marine
actinobacterium PHSC20C1
Length = 288
Score = 56.0 bits (129), Expect = 1e-06
Identities = 45/152 (29%), Positives = 63/152 (41%), Gaps = 4/152 (2%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 297
K+ +VGSG +G L A G V V+DV + A + L + +R E
Sbjct: 5 KLAVVGSGTMGHGIGQLAAMQGIAVRVFDVDEVALDRARASVATSL-----ERFVRKETI 59
Query: 298 ASEQFQCIKG----STDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXX 465
Q I+G +TDL+ A+ G E VPE L LK+KVF +LD +
Sbjct: 60 TDAQSHEIQGRMDWTTDLDAALVGVEAAIEAVPEVLALKQKVFTDLDERTGPEVMLATNT 119
Query: 466 XXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
KH +V+ H NPP + L
Sbjct: 120 SQLSITTIASSAKHPERVVGMHFFNPPVVMRL 151
>UniRef50_Q8G825 Cluster: Possible butyryl-CoA dehydrogenase; n=2;
Bifidobacterium longum|Rep: Possible butyryl-CoA
dehydrogenase - Bifidobacterium longum
Length = 319
Score = 55.6 bits (128), Expect = 2e-06
Identities = 38/147 (25%), Positives = 59/147 (40%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
I VG+G +G + + FA GY V + + A++ I+ GLL+
Sbjct: 11 IANVGTGTMGHAITLQFALAGYPVHLVGRSEASLEKAMKAIRSDAEDFAEAGLLKAGDTV 70
Query: 301 SEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 480
I G D + V FV E V ENLD+KK V+ ++ + I
Sbjct: 71 DTVLARITGYADYASGVADVDFVIESVAENLDVKKSVWTEVEHAAPKDAILSTNTSGLSP 130
Query: 481 XXXXEGLKHKSQVIVSHPVNPPYYVPL 561
+ H + +V+H NP +PL
Sbjct: 131 TALQSVMGHPERFVVAHFWNPAQLMPL 157
Score = 48.8 bits (111), Expect = 2e-04
Identities = 23/54 (42%), Positives = 35/54 (64%)
Frame = +2
Query: 557 PLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEVW 718
PLVE+VP T P+V T ++M +IG++P + +E FV NR+Q A+L E +
Sbjct: 156 PLVEVVPGEKTDPKVVDITFDLMAKIGKKPAKIKKESLGFVGNRLQLAVLREAF 209
>UniRef50_Q891F6 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxybutyryl-coA dehydrogenase -
Clostridium tetani
Length = 282
Score = 55.2 bits (127), Expect = 2e-06
Identities = 37/143 (25%), Positives = 65/143 (45%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
+KI ++G+G +G A FA+ GY+V + D+ + + I+ I+ L L + G + E
Sbjct: 2 KKICVLGAGTMGAGIAQAFAAKGYEVVLRDIKDEFVERGIKGIEKGLSKLVSKGRMAQE- 60
Query: 295 KASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 474
I+G+ DL A + V+ + EN+++K+++F LD + TI
Sbjct: 61 DMDSILGRIEGTVDLNKAADCDLVVEAAI-ENMEIKREIFAELDRICKPETILSSNTSSL 119
Query: 475 XXXXXXEGLKHKSQVIVSHPVNP 543
+VI H NP
Sbjct: 120 SITEIATATNRPDKVIGMHFFNP 142
>UniRef50_Q4J6T7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Archaea|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Sulfolobus acidocaldarius
Length = 657
Score = 55.2 bits (127), Expect = 2e-06
Identities = 38/149 (25%), Positives = 66/149 (44%), Gaps = 1/149 (0%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 297
++G+VG+G +G A + A G+ V + DV + +A+E I++ L L + ++K
Sbjct: 6 RVGVVGAGTMGHGIAEVVAIAGFNVVLTDVNEDILRNALEKIRWSLEKLRE----KRQIK 61
Query: 298 ASEQFQCIKGSTDLETA-VKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 474
+ + T + F+ E E D+K+K+F LD VV + I
Sbjct: 62 ENPNTVLSRIKTTVSFGDFSDVDFIIEAAIERSDVKRKIFSELDRVVKKDAIFATNTSTI 121
Query: 475 XXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
E + + I H +NPP +PL
Sbjct: 122 PISYLAEVTGRQEKFIGLHFMNPPVLMPL 150
Score = 33.1 bits (72), Expect = 9.7
Identities = 15/48 (31%), Positives = 28/48 (58%)
Frame = +2
Query: 548 ITYPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRI 691
+ PLVEI+ T E K T ++ ++I + V + +++ F++NRI
Sbjct: 146 VLMPLVEIIMGNKTAEETLKTTIDLAKKINKDYVVVKKDVPGFLINRI 193
>UniRef50_Q5P039 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum
(strain EbN1))
Length = 443
Score = 54.8 bits (126), Expect = 3e-06
Identities = 34/111 (30%), Positives = 59/111 (53%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 297
++G++G+G +G AM FA+VG VTV D + +E ++ G L
Sbjct: 43 RVGVIGAGTMGGGIAMSFANVGIPVTVCDTDGAALERGLERVRRNYEFSVARGRLDAATM 102
Query: 298 ASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTI 450
A+ + I+ + DL+ +K A V E V E++ LK+ +F+ LD++V + I
Sbjct: 103 AA-RLALIRAAVDLQD-LKDADLVIEAVFEDMALKQDIFRKLDAIVHPDAI 151
>UniRef50_Q1DAC1 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Myxococcus xanthus DK 1622|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Myxococcus xanthus
(strain DK 1622)
Length = 321
Score = 54.4 bits (125), Expect = 4e-06
Identities = 40/149 (26%), Positives = 66/149 (44%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
++IG+VG G +G A+ A G QV +Y+ A A ++ L GLL E
Sbjct: 7 KRIGMVGGGAMGCGIALELAIAGRQVVLYNTRADSSERARAKLERDASLLVETGLLAPE- 65
Query: 295 KASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 474
+A I+ +T L A V E +PE+L LK+++F+ LD + +T+
Sbjct: 66 QAPAAIGRIRRTTVLAEAAVEQDLVIESIPEDLALKQQLFRELDQLAAPDTLLATNTTAL 125
Query: 475 XXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
+V+ +H P + +PL
Sbjct: 126 SVTAIARDCTRPERVLSAHYYLPAHLIPL 154
Score = 47.6 bits (108), Expect = 4e-04
Identities = 23/60 (38%), Positives = 36/60 (60%)
Frame = +2
Query: 542 HLITYPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEVWR 721
HLI PLV+I+P T P+ + R +EE+G+ PV +R++ V R+Q A++ E R
Sbjct: 150 HLI--PLVDIIPGEKTSPDAVETVRRFIEELGKSPVVFSRDVPGSVGPRLQQALIGEAIR 207
>UniRef50_A3U7V8 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerasefamily protein; n=19; Bacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerasefamily protein - Croceibacter
atlanticus HTCC2559
Length = 802
Score = 54.4 bits (125), Expect = 4e-06
Identities = 47/172 (27%), Positives = 81/172 (47%), Gaps = 18/172 (10%)
Frame = +1
Query: 100 SKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITD-------AIEDIKYQLH 258
+K + KI ++GSG++G A FA++G +V + D+V +++ + +ED K +
Sbjct: 2 AKRRINKIAVIGSGIMGSGIACHFANIGVEVLLLDIVPRELNEKEKAKGLTLED-KVVRN 60
Query: 259 TLENDGLLRGELKAS------EQFQCIKGSTDLE---TAVKGAIFVQECVPENLDLKKKV 411
+ ND L+ +K+ + F + +LE VK ++ E V E LD+KK+V
Sbjct: 61 RIVNDA-LQSSIKSKPAPLYHKDFASRISTGNLEDDIAKVKDVDWIIEVVVERLDIKKQV 119
Query: 412 FQNLDSVVDDNTIXXXXXXXXXXXXXXEGLKHKSQ--VIVSHPVNPPYYVPL 561
F+NL+ + T+ EG Q +H NPP Y+ L
Sbjct: 120 FENLEKHRTEGTLITSNTSGIPINLMSEGRSEDFQKHFCGTHFFNPPRYLEL 171
>UniRef50_A1SSP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Psychromonas ingrahamii 37|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Psychromonas ingrahamii (strain 37)
Length = 511
Score = 54.4 bits (125), Expect = 4e-06
Identities = 37/147 (25%), Positives = 69/147 (46%)
Frame = +1
Query: 103 KFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLL 282
K + + ++G+G +G A + A GYQV ++D+ + +A E+I+ QL G +
Sbjct: 3 KLLFKTVAVIGAGAMGAGIAQVAAQSGYQVYLFDLAKGKAEEAKENIEKQLERRVKKGRM 62
Query: 283 RGELKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXX 462
+ S + I S++L + + A V E + ENL++K+ +F+ L+++ + I
Sbjct: 63 EQQTLESTLLR-IHCSSEL-SEIASANLVIEAIVENLEIKQGLFKELETICSADCILASN 120
Query: 463 XXXXXXXXXXEGLKHKSQVIVSHPVNP 543
LK + I H NP
Sbjct: 121 TSSISITAIASALKSPERFIGLHFFNP 147
>UniRef50_A2QXC7 Cluster: Contig An11c0270, complete genome.
precursor; n=6; Pezizomycotina|Rep: Contig An11c0270,
complete genome. precursor - Aspergillus niger
Length = 599
Score = 54.4 bits (125), Expect = 4e-06
Identities = 33/107 (30%), Positives = 53/107 (49%)
Frame = +1
Query: 112 SEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGE 291
S + ++G+G++GR A +FA+ GY V +YD A++ + L T
Sbjct: 12 SRPLALLGAGVLGRRIACVFAAAGYNVNLYDPSLSAQQAALDYVTQNLKTYSKFS----- 66
Query: 292 LKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSV 432
K + +F + +DLE+ V A V E VPE+L +K V LD +
Sbjct: 67 -KGNRRFGHCRAFSDLESTVSDAWLVIEAVPEHLQMKIDVMGELDKL 112
Score = 37.1 bits (82), Expect = 0.60
Identities = 20/52 (38%), Positives = 29/52 (55%)
Frame = +2
Query: 560 LVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEV 715
+VE++ T PEV ++E++G PV+ RE FV NR+ AI EV
Sbjct: 156 VVELMTDGETWPEVFPFLTRVLEDVGMVPVTARRESTGFVFNRLWAAIKREV 207
>UniRef50_O69856 Cluster: Fatty acid oxidation complex
alpha-subunit; n=6; Actinobacteria (class)|Rep: Fatty
acid oxidation complex alpha-subunit - Streptomyces
coelicolor
Length = 709
Score = 54.0 bits (124), Expect = 5e-06
Identities = 38/149 (25%), Positives = 67/149 (44%), Gaps = 1/149 (0%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLF-ASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
K+G+VG+GL+ A+LF + V + D+ +++ + + ++ L G + +
Sbjct: 340 KVGVVGAGLMASQLALLFLRRLEVPVVLTDIDQERVDKGVGYVHAEIDKLLGKGRVNQD- 398
Query: 295 KASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 474
KA+ + G D A FV E V E + +K+KVF +++V + I
Sbjct: 399 KANRLKALVTGVLDKAEGFADADFVIEAVFEEMGVKQKVFAEVEAVAPAHAILATNTSSL 458
Query: 475 XXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
LKH +V+ H NP +PL
Sbjct: 459 SVSEMASKLKHPERVVGFHFFNPVAILPL 487
>UniRef50_Q4J0Z7 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
C-terminal:3-hydroxyacyl-CoA dehydrogenase, NAD binding
domain; n=2; Gammaproteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, C-terminal:3-hydroxyacyl-CoA
dehydrogenase, NAD binding domain - Azotobacter
vinelandii AvOP
Length = 307
Score = 54.0 bits (124), Expect = 5e-06
Identities = 37/147 (25%), Positives = 69/147 (46%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
I I+G+GL+G A A G+ V + D A+++ + L L + G R E
Sbjct: 6 IVILGAGLMGIGIATHLARHGHAVLLRDPAAERLAEVPVMAGSILAELADAG--RFERAQ 63
Query: 301 SEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 480
++ + V A + E +PE L+LK+ ++ L+++V T+
Sbjct: 64 TDATLARLAVSPRLADVADARLLIEAIPERLELKRALYAELEALVGTGTVIASNTSGLPP 123
Query: 481 XXXXEGLKHKSQVIVSHPVNPPYYVPL 561
EG++H +++++H NPP+ +PL
Sbjct: 124 DALAEGMRHPERLLIAHFWNPPHLIPL 150
Score = 41.1 bits (92), Expect = 0.037
Identities = 23/57 (40%), Positives = 34/57 (59%)
Frame = +2
Query: 542 HLITYPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDE 712
HLI PLVEIVP T+ E + R ++ + + V L + I F+ NR+Q+A+L E
Sbjct: 146 HLI--PLVEIVPGSATRAEHLEAVRTLLAGMELEAVVLDKAIPGFIGNRLQFAVLRE 200
>UniRef50_Q89HA7 Cluster: Blr6087 protein; n=6; Proteobacteria|Rep:
Blr6087 protein - Bradyrhizobium japonicum
Length = 330
Score = 53.6 bits (123), Expect = 6e-06
Identities = 43/155 (27%), Positives = 72/155 (46%), Gaps = 8/155 (5%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDV-------VAKQITDAIEDIKYQLHTLENDGL 279
I +G+G +GR A+ FA G++VT+ DV AK TDA+ +++ +L N GL
Sbjct: 7 IACLGAGRMGRGIAVAFAYAGHRVTMIDVKPRSAEDFAKLETDALGEVRKTFASLSNLGL 66
Query: 280 L-RGELKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXX 456
L ++ + ++ TA+ A V E VPE ++LK++V V +TI
Sbjct: 67 LTEADVDPLVARVSVATASQSGTALADAGMVFEGVPEVVELKREVLGAASRQVKPDTIIA 126
Query: 457 XXXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
+ + + + H +NP Y +PL
Sbjct: 127 STTSTILVDDLSGAIVNPHRFLNVHWLNPAYLIPL 161
>UniRef50_Q12D24 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=5; Burkholderiales|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 511
Score = 53.6 bits (123), Expect = 6e-06
Identities = 39/157 (24%), Positives = 70/157 (44%)
Frame = +1
Query: 73 TVASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQ 252
T+ STV +K + +VG+G++G A + A G+ V +YD +A +
Sbjct: 2 TMNSTV---NKLDEAPLLVVGAGVMGVGIAQVAAQAGHAVMLYDAREGAAAEAKTKLAKS 58
Query: 253 LHTLENDGLLRGELKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSV 432
L L G L + S+ I+ L A + + E + E LD+K+ +FQ L+++
Sbjct: 59 LDALVAKGKLTAQ-GVSQTLSRIEAIASLAAAAPARLVI-EAIVEKLDVKRGLFQQLEAI 116
Query: 433 VDDNTIXXXXXXXXXXXXXXEGLKHKSQVIVSHPVNP 543
V + + GL+H ++++ H NP
Sbjct: 117 VAADCVLATNTSSISVTAIANGLQHPARLVGMHFFNP 153
>UniRef50_A0VLT7 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Dinoroseobacter shibae DFL 12|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Dinoroseobacter shibae DFL 12
Length = 391
Score = 53.6 bits (123), Expect = 6e-06
Identities = 45/147 (30%), Positives = 67/147 (45%), Gaps = 3/147 (2%)
Frame = +1
Query: 127 IVGSGLIGRSWAMLFASVGYQVTVYDV---VAKQITDAIEDIKYQLHTLENDGLLRGELK 297
I+GSG IG WA F G+ V V+D ++T IE + L L D L +
Sbjct: 7 IIGSGRIGSGWAARFLLFGWHVRVFDADPGAQARLTQVIEAARTSLLGLY-DTPLPPPGR 65
Query: 298 ASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 477
S+ GS + AV GA++VQE VPE+L LK++V + + + I
Sbjct: 66 LSQH-----GS--IAEAVAGAVWVQESVPEDLSLKREVVREVQA-HGPEAIVASAASDIP 117
Query: 478 XXXXXEGLKHKSQVIVSHPVNPPYYVP 558
EG +V+++ V P Y +P
Sbjct: 118 LEALREGAARPERVVIARAVAPVYLLP 144
>UniRef50_O29815 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 304
Score = 53.6 bits (123), Expect = 6e-06
Identities = 38/111 (34%), Positives = 57/111 (51%), Gaps = 3/111 (2%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIK---YQLHTLENDGLLR 285
EKIG+VG GL+G FA G +V DV +++ +E IK + L L G +
Sbjct: 3 EKIGVVGFGLMGTQITQFFAQQGLEVVAIDVSEERLRKGMEAIKAGRFGLQRLVEKGKIT 62
Query: 286 GELKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVD 438
E + + I ST +A+K V E V E+++LK KV + +D+V D
Sbjct: 63 EE-EMNAVLSRISTSTS-HSALKDCDLVIEAVFEDVNLKLKVLREIDAVTD 111
>UniRef50_Q397D0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=31;
Proteobacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 518
Score = 53.2 bits (122), Expect = 8e-06
Identities = 37/141 (26%), Positives = 61/141 (43%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
+G++G+G +G A + A+ G+ V +YD+ A+ I+ Q L G L +A
Sbjct: 20 VGVIGAGAMGAGIAQVAAAAGHTVLLYDLNEAACDKALAGIRAQFARLAEKGRLE-PAQA 78
Query: 301 SEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 480
I+ +L GA + E E LD+K+++F L+ VDD +
Sbjct: 79 DAAGARIRAVREL-ADFAGAALIVEAAAERLDVKREIFATLERHVDDACLLATNTSSISI 137
Query: 481 XXXXEGLKHKSQVIVSHPVNP 543
GL+ +V H NP
Sbjct: 138 TSIAAGLRVPQRVAGLHFFNP 158
>UniRef50_A7PEM6 Cluster: Chromosome chr11 scaffold_13, whole genome
shotgun sequence; n=3; core eudicotyledons|Rep:
Chromosome chr11 scaffold_13, whole genome shotgun
sequence - Vitis vinifera (Grape)
Length = 724
Score = 53.2 bits (122), Expect = 8e-06
Identities = 35/149 (23%), Positives = 67/149 (44%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
+K+ ++G GL+G A + V + +V ++ + I+ I+ + L G L +
Sbjct: 309 KKVAVIGGGLMGSGIATALITSNIYVVLKEVNSEYLLKGIKTIEANVRGLVTKGKLTQD- 367
Query: 295 KASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 474
KA + +KG D + K V E V EN+ LK+K+F ++ + + I
Sbjct: 368 KARKALSMLKGVLDY-SEFKDIDMVIEAVIENISLKQKIFSEIEKICSPHCILATNTSTI 426
Query: 475 XXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
E + ++I +H +P + +PL
Sbjct: 427 DLNLVGEKTSSQDRIIGAHFFSPAHVMPL 455
>UniRef50_Q9XA30 Cluster: Putative 3-Hydroxyacyl-CoA dehydrogenase;
n=2; Streptomyces|Rep: Putative 3-Hydroxyacyl-CoA
dehydrogenase - Streptomyces coelicolor
Length = 504
Score = 52.8 bits (121), Expect = 1e-05
Identities = 38/150 (25%), Positives = 67/150 (44%)
Frame = +1
Query: 112 SEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGE 291
S + +VG+G +G+ A + G+ V +YD V + +A + I +L L L G
Sbjct: 7 SSPVAVVGTGTMGQGIAQVALVAGHPVRLYDAVDGRAREAADAIGARLDRLVEKDRLTGA 66
Query: 292 LKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 471
+ + + + + T E A V E V E LD+K+++F+ L+ VV D+ +
Sbjct: 67 ERDAARARLVPAGTLGELA--DCALVVEAVVERLDVKQELFRALEDVVGDDCLLATNTSS 124
Query: 472 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
L+ + + H NP +PL
Sbjct: 125 LSVTAVGGALRVPGRFVGLHFFNPAPLLPL 154
>UniRef50_Q0LRY2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=2; Alphaproteobacteria|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Caulobacter sp. K31
Length = 348
Score = 52.4 bits (120), Expect = 1e-05
Identities = 39/149 (26%), Positives = 65/149 (43%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
+ + ++G+GL+G A +FA+ GY V ++D T A I G +
Sbjct: 47 QPVAVLGAGLMGAGIAKVFAAKGYPVFLFDRDLDTATSATRQIN-------------GAI 93
Query: 295 KASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 474
+ + + + L AV A FV E V E LD+K+++F L + +
Sbjct: 94 AHVDGGRDVDAAGSLAEAVADAAFVFESVSEKLDVKRRIFSALAECARHDAVLASNTSAI 153
Query: 475 XXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
EGL +++++ SH NP VPL
Sbjct: 154 PITQIAEGLPCEARIVGSHWWNPADVVPL 182
Score = 38.7 bits (86), Expect = 0.20
Identities = 18/52 (34%), Positives = 31/52 (59%)
Frame = +2
Query: 557 PLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDE 712
PLVE+VP T + +++ +G++ V + R+I FV NR+Q+A+ E
Sbjct: 181 PLVEVVPGIATDAHHVEAMMQLLISVGKKAVRIDRDIPGFVGNRLQFALWRE 232
>UniRef50_A0LSM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5;
Actinomycetales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 301
Score = 52.4 bits (120), Expect = 1e-05
Identities = 39/143 (27%), Positives = 65/143 (45%), Gaps = 2/143 (1%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDG-LLRGELK 297
+G+VGSGL+G A + A GY V ++D+ + A+ I LH L G L +++
Sbjct: 10 VGVVGSGLMGSGIAQVAAVAGYAVRLHDIEESALHRALTTIDESLHRLARKGKLSTSDVE 69
Query: 298 ASE-QFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 474
A++ + + DL + V E V E LD+K+ VF L ++V N +
Sbjct: 70 AAKARITTTRRLADL----ADSDVVVEAVYEELDVKRVVFAELAAIVRPNVLLASNTTAI 125
Query: 475 XXXXXXEGLKHKSQVIVSHPVNP 543
G+ +V+ H +P
Sbjct: 126 PITHIASGVSGPQRVVGMHFFSP 148
>UniRef50_Q67SZ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Symbiobacterium thermophilum
Length = 517
Score = 52.0 bits (119), Expect = 2e-05
Identities = 31/111 (27%), Positives = 59/111 (53%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 297
++G+VG+G +G A + A G+ V +YDV + + A+ ++ L G + + +
Sbjct: 3 RLGVVGAGTMGAGIAQVAAQSGFDVLLYDVDPEALARALGRVESDLQRQAARGRI-PDAQ 61
Query: 298 ASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTI 450
+E I +T L A FV E PE+L+LK+++F+ LD + ++ +
Sbjct: 62 VAEVLGRITTTTSLGD-FAAADFVIEAAPEDLELKRRLFERLDRLCREDVV 111
>UniRef50_Q68WH7 Cluster: Putative fatty acid oxidation complex
trifunctional enzyme [Includes: 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35); Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase (EC 4.2.1.17) (EC 5.3.3.8)]; n=20;
Rickettsia|Rep: Putative fatty acid oxidation complex
trifunctional enzyme [Includes: 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35); Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase (EC 4.2.1.17) (EC 5.3.3.8)] - Rickettsia typhi
Length = 720
Score = 52.0 bits (119), Expect = 2e-05
Identities = 36/151 (23%), Positives = 67/151 (44%), Gaps = 2/151 (1%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
+K+ ++G+G++G A L A+ ++V + D++ K D + +K + L L
Sbjct: 6 KKVCVIGAGVMGSGIAALIANSSHRVVLLDILDKDSNDPNKIVKNAVKNLHRQKLPPLSY 65
Query: 295 KASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 474
F I +K V E + E LD+K +++ + + ++TI
Sbjct: 66 PDKVNFITIGNLEHDLDLIKECNLVIEVIVEKLDIKHQLYNKIIPYLKEDTIIASNTSTL 125
Query: 475 XXXXXXEGLKH--KSQVIVSHPVNPPYYVPL 561
E L + KS+ I++H NPP Y+ L
Sbjct: 126 PLKKLKENLPNNIKSRFIITHFFNPPRYMEL 156
>UniRef50_Q0SEM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 286
Score = 51.6 bits (118), Expect = 3e-05
Identities = 38/141 (26%), Positives = 62/141 (43%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
+G+VG+G +G A A G+ V V D + + A ++ L G G K
Sbjct: 9 VGVVGAGTMGAGVAECLAQAGHDVIVVDPDPQAVDQARSRMRDSLRLAILLGRAGGP-KP 67
Query: 301 SEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 480
+E + + ++ T ++ A V ECVPE +DLK+KVF LD V + +
Sbjct: 68 AEVTARVHWTGEM-TDLRDAAVVIECVPERIDLKEKVFAELDRVCAPDALLASCTSGIPV 126
Query: 481 XXXXEGLKHKSQVIVSHPVNP 543
+ +V+ H +NP
Sbjct: 127 DRLADTTTRPERVVGLHFMNP 147
>UniRef50_Q11TH9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=16;
Bacteroidetes|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Length = 298
Score = 51.2 bits (117), Expect = 3e-05
Identities = 40/139 (28%), Positives = 57/139 (41%)
Frame = +1
Query: 127 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASE 306
I+GSG +G A FA G+QV + D A + A+ I L + G++ K +
Sbjct: 10 IIGSGTMGSGIAHSFAQFGFQVFLCDSNAAALNKAMLQISTNLERQISKGIIPDSEKET- 68
Query: 307 QFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXX 486
I TD + A K V E VPE L++K +F+ LD TI
Sbjct: 69 IISRITPITDFKEAAKTVSLVVEAVPELLEIKADLFKELDMHCPPETILASNTSSISITT 128
Query: 487 XXEGLKHKSQVIVSHPVNP 543
+VI H +NP
Sbjct: 129 LASYTSRPEKVIGMHFMNP 147
>UniRef50_Q7VRZ0 Cluster: Probable enoyl-CoA
hydratase/3-hydroxyacyl-CoA dehydrogenase, bifunctional
enzyme; n=3; Bordetella|Rep: Probable enoyl-CoA
hydratase/3-hydroxyacyl-CoA dehydrogenase, bifunctional
enzyme - Bordetella pertussis
Length = 705
Score = 50.8 bits (116), Expect = 5e-05
Identities = 34/139 (24%), Positives = 62/139 (44%)
Frame = +1
Query: 127 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASE 306
+VG+G +GR A+ A G +V DV + A+E I+ +L G + E A +
Sbjct: 308 VVGAGTMGRGIAIALADAGLRVRFIDVEQASLDRALEAIRAHYRSLAARGRMT-EAAARD 366
Query: 307 QFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXX 486
I ++D++ A + + V E E+L +K+ +F+ LDS+V +
Sbjct: 367 AVARISPASDMQAAAEADVVV-EAAFEDLAIKQAIFRQLDSIVRPGAVLATNTSTLDVDA 425
Query: 487 XXEGLKHKSQVIVSHPVNP 543
+ V+ +H +P
Sbjct: 426 IAAATRRPQDVVGTHFFSP 444
>UniRef50_Q6V1N6 Cluster: PlmT8; n=1; Streptomyces sp. HK803|Rep:
PlmT8 - Streptomyces sp. HK803
Length = 571
Score = 50.8 bits (116), Expect = 5e-05
Identities = 33/113 (29%), Positives = 56/113 (49%)
Frame = +1
Query: 112 SEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGE 291
+ +IG+VGSG + A A GY T+ + +A+ ++ L+ G L E
Sbjct: 290 ARRIGVVGSGTMATGIAQACARAGYPTTLVARSEVRAKEALATVENSLNRAVQRGRLTPE 349
Query: 292 LKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTI 450
+ + + + G + LE AV V E V E++D+K+ VF+ LD+V T+
Sbjct: 350 -QLTSSMESLTGVSRLE-AVAACDLVVEAVVEDIDVKRTVFRELDAVCGAQTV 400
>UniRef50_Q16836 Cluster: Hydroxyacyl-coenzyme A dehydrogenase,
mitochondrial precursor; n=40; Eukaryota|Rep:
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
precursor - Homo sapiens (Human)
Length = 314
Score = 50.8 bits (116), Expect = 5e-05
Identities = 37/139 (26%), Positives = 63/139 (45%), Gaps = 5/139 (3%)
Frame = +1
Query: 49 FTRGLSCGTVASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITD 228
F R +S + AS A K + + ++G GL+G A + A+ G+ V + D +
Sbjct: 8 FMRSVSSSSTASA--SAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAK 65
Query: 229 AIEDIKYQLHTLENDGLLRGELKASEQF-----QCIKGSTDLETAVKGAIFVQECVPENL 393
+ + I+ L + KA ++F I STD + V V E + ENL
Sbjct: 66 SKKGIEESLRKVAKKKFAENP-KAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENL 124
Query: 394 DLKKKVFQNLDSVVDDNTI 450
+K ++F+ LD ++TI
Sbjct: 125 KVKNELFKRLDKFAAEHTI 143
>UniRef50_Q1IMY8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Acidobacteria bacterium Ellin345|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Acidobacteria bacterium (strain Ellin345)
Length = 278
Score = 50.4 bits (115), Expect = 6e-05
Identities = 31/110 (28%), Positives = 58/110 (52%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
I ++G+G +GRS A A G++ + D++ + A + I+ +L + G + + +A
Sbjct: 7 IAVIGAGTMGRSIAQAAAVGGFRTILEDILPNALRKAEDAIRAELGRAVSTGSVE-QREA 65
Query: 301 SEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTI 450
I+ +++LE A + A V E VP+ L+ K ++F LD V T+
Sbjct: 66 DAALARIEYASNLEDAARDADMVIEAVPDELESKLEIFVLLDKVCRPETM 115
>UniRef50_A5IDB6 Cluster: 3-hydroxyacyl CoA dehydrogenase; n=9;
Gammaproteobacteria|Rep: 3-hydroxyacyl CoA dehydrogenase
- Legionella pneumophila (strain Corby)
Length = 284
Score = 50.4 bits (115), Expect = 6e-05
Identities = 39/154 (25%), Positives = 66/154 (42%), Gaps = 3/154 (1%)
Frame = +1
Query: 109 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG 288
K K+ ++G+G +G LFA G+ VT+ D + Q+ A + I LH L L
Sbjct: 2 KQTKLTLLGAGTMGSGITQLFAQYGFYVTLIDNLQSQLDKAKDTIAKNLHYL----ALTQ 57
Query: 289 ELKASEQFQCIKGSTDLET---AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXX 459
L+++ + I S T +K + ++ E + EN + KK ++Q L I
Sbjct: 58 NLESTHSIETILASITFTTKLDELKQSEYIIENITENWERKKALYQVLKKECSATCILGV 117
Query: 460 XXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
+ H +VI H +NP +P+
Sbjct: 118 NTSSIPITKIASLVDHPQRVIGVHFMNPAPMMPM 151
>UniRef50_A1I839 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Candidatus
Desulfococcus oleovorans Hxd3
Length = 289
Score = 50.4 bits (115), Expect = 6e-05
Identities = 36/113 (31%), Positives = 57/113 (50%), Gaps = 1/113 (0%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
+++ I G+G +GRS + A G +V +YDV + A + ++ + G L E
Sbjct: 7 KRVLIAGAGTMGRSIGLSCAVRGCEVILYDVKEDALEAARRAMAVKIDKMVPAGALTPE- 65
Query: 295 KASEQFQC-IKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTI 450
A+E + I +TDL A A V E VPE+ D+K + F+ L V + TI
Sbjct: 66 -AAESIKANITTTTDLAAAGADADLVSESVPEDPDIKGEFFEKLHGVCPERTI 117
>UniRef50_A7D676 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Halorubrum lacusprofundi ATCC
49239|Rep: 3-hydroxyacyl-CoA dehydrogenase, NAD-binding
- Halorubrum lacusprofundi ATCC 49239
Length = 676
Score = 50.4 bits (115), Expect = 6e-05
Identities = 35/150 (23%), Positives = 64/150 (42%), Gaps = 1/150 (0%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTL-ENDGLLRGE 291
+++ ++G+G +G A + A GY V + D+ + + + I++ L L E D + GE
Sbjct: 20 QRVTVLGAGNMGHGIAEVAALAGYDVALRDIEEEFVQGGYDQIEWSLGKLAEKDRI--GE 77
Query: 292 LKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 471
+A ++ DLE ++ A V E VPE + +KK V+ + + +
Sbjct: 78 DEADAALDRVEAFVDLEDSLADADVVVEVVPEKMAIKKDVYDEVVEYAPEEAVFVTNTSS 137
Query: 472 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
E + H NPP + L
Sbjct: 138 LSITELSEVTDRPERFCGMHFFNPPVRMDL 167
>UniRef50_A4YDR4 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=2; Sulfolobaceae|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Metallosphaera sedula DSM 5348
Length = 334
Score = 50.4 bits (115), Expect = 6e-05
Identities = 36/148 (24%), Positives = 66/148 (44%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 297
K+ ++GSG++G +FA G++VT+YDV + + A+E I++ L L+ G ++
Sbjct: 2 KVFVIGSGVMGSGIGQVFAMAGHEVTLYDVKEEALKKAMEGIRWSLQKLQEKGSVK---D 58
Query: 298 ASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 477
I S DL A + E V E++ +K V + + D+ I
Sbjct: 59 VESVLSRIFTSRDLSEARDHLVI--EAVFEDIKVKSDVLGRVSPLTDE--IIASNTSSLP 114
Query: 478 XXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
+++ + + H NPP + L
Sbjct: 115 ITELSRAVRNPERFLGMHFFNPPVLMKL 142
>UniRef50_Q62DG4 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=48; Bacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Burkholderia mallei
(Pseudomonas mallei)
Length = 331
Score = 50.0 bits (114), Expect = 8e-05
Identities = 39/156 (25%), Positives = 56/156 (35%)
Frame = +1
Query: 94 MASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLEND 273
MA K + +G+G+IG W + G V +D +++ LE
Sbjct: 11 MAVITKIDTFAAIGAGVIGSGWVARALANGLDVLAWDPAEDAEMQLRANVENAWPALERA 70
Query: 274 GLLRGELKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIX 453
GL G A F +E V A FVQE PE LK ++ + + + I
Sbjct: 71 GLAPGASPARLHFV-----PTIEACVADADFVQESAPEREALKLELHERISRAAKPDAII 125
Query: 454 XXXXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
+ IV HP NP Y +PL
Sbjct: 126 ASSTSGLLPTDFYARAHRPERCIVGHPFNPVYLLPL 161
>UniRef50_Q28UL9 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=3; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding - Jannaschia
sp. (strain CCS1)
Length = 687
Score = 50.0 bits (114), Expect = 8e-05
Identities = 39/113 (34%), Positives = 52/113 (46%), Gaps = 2/113 (1%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 297
KI IVG G +G A SVG V + + A DAI ++ + TL GL RG L
Sbjct: 284 KIAIVGGGTMGAGIAYACLSVGLPVVLLETDA----DAIARAQHNIDTLIGAGLKRGRLD 339
Query: 298 ASEQFQCIKGSTDLE--TAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTI 450
S T E A A V E E++D+KK +F LD+ V +T+
Sbjct: 340 DSGAAALRDRLTLTEDYAAASDATLVIEAAFESMDVKKDIFAKLDAAVSPDTV 392
>UniRef50_Q0FUM2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Rhodobacterales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Roseovarius sp. HTCC2601
Length = 220
Score = 50.0 bits (114), Expect = 8e-05
Identities = 37/151 (24%), Positives = 65/151 (43%), Gaps = 1/151 (0%)
Frame = +1
Query: 112 SEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGE 291
S +I +VG+G +G A L+A GY + D + +E + L D
Sbjct: 13 SGRICVVGAGFMGCVIATLYAHHGYDAVICDSNQTMLDTYVERARPIAAGLVEDS----- 67
Query: 292 LKASEQFQC-IKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXX 468
ASE + DL +A++G V E V E+L++K+ +F L+ + +N +
Sbjct: 68 -DASEAMLAGVTLEPDLASAIEGVFLVHEAVQESLEVKQALFAELERICPENVVLATNTS 126
Query: 469 XXXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
+ K +++ H V P + VP+
Sbjct: 127 SFLISDIAAQMTRKERMMGIHYVTPGHIVPV 157
Score = 36.3 bits (80), Expect = 1.0
Identities = 21/65 (32%), Positives = 39/65 (60%), Gaps = 4/65 (6%)
Frame = +2
Query: 539 IHLIT----YPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAIL 706
IH +T P++E++ A T E+ +R +++ I V++ E F++NRIQ+A+L
Sbjct: 146 IHYVTPGHIVPVIELIHAADTPAELVAWSRMLVQNIEHVGVAIL-ERPGFLVNRIQFAML 204
Query: 707 DEVWR 721
E++R
Sbjct: 205 TEIYR 209
>UniRef50_A0QZR0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Mycobacterium smegmatis str. MC2 155|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Mycobacterium
smegmatis (strain ATCC 700084 / mc(2)155)
Length = 296
Score = 50.0 bits (114), Expect = 8e-05
Identities = 35/144 (24%), Positives = 65/144 (45%), Gaps = 3/144 (2%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
+ ++G+G +G A + A G++ +YD+ + I+ + H + + G+L A
Sbjct: 12 VAVLGAGTMGSGIATVMARAGHRTILYDINEANLERGIDTV----HGFFDKSVRLGKLDA 67
Query: 301 S---EQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 471
+ + GST+L+ + V E V E+L LKK+ F LD +V T+
Sbjct: 68 TAGQAAKDSLSGSTELKDLAPCDVVV-EAVFEDLSLKKETFGRLDDIVPPTTLFHTNTST 126
Query: 472 XXXXXXXEGLKHKSQVIVSHPVNP 543
G + + +V+ +H NP
Sbjct: 127 LSVTGIASGSRLRERVVGTHYCNP 150
>UniRef50_P34439 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenase
F54C8.1; n=2; Caenorhabditis|Rep: Probable
3-hydroxyacyl-CoA dehydrogenase F54C8.1 - Caenorhabditis
elegans
Length = 298
Score = 49.6 bits (113), Expect = 1e-04
Identities = 40/146 (27%), Positives = 64/146 (43%), Gaps = 5/146 (3%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
+ IVGSG +G A + AS G+ V + DV K + A++ I + L +G K
Sbjct: 14 VAIVGSGQMGSGIAQVTASSGFNVMLADVNKKALDRAMKAISQSVTHLSKKQ--KGTDKE 71
Query: 301 SEQFQC-----IKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXX 465
F IK ++ TAV A + E EN+DLK+ +F ++ ++I
Sbjct: 72 KSDFVTLTMSRIKTCNNVSTAVADADLIIEAAIENIDLKRGIFAQIEQSCKKDSILTTNT 131
Query: 466 XXXXXXXXXEGLKHKSQVIVSHPVNP 543
+GL+ K++ H NP
Sbjct: 132 SSFLLEDVAKGLQDKTRFGGLHFFNP 157
>UniRef50_Q46MP3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
Burkholderiales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Ralstonia eutropha (strain JMP134) (Alcaligenes
eutrophus)
Length = 304
Score = 49.2 bits (112), Expect = 1e-04
Identities = 37/148 (25%), Positives = 72/148 (48%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 297
++ ++G+GL+G A+ F + + V ++D V+ Q +A+ + + H LE L G+ +
Sbjct: 10 RVAVLGAGLMGHGIALAFMTSDFDVAIWDPVS-QAREAVRE-RIAEH-LE----LMGDPR 62
Query: 298 ASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 477
+ C + L+ V+ V E PE++ K+++ + +D +V+ I
Sbjct: 63 GVDVRVC----STLQDCVRDCDIVVEAAPESVSTKRELIREID-LVNSECIIASNTSVLR 117
Query: 478 XXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
EG +V+ +H NPPY +PL
Sbjct: 118 ITEIAEGSADPGRVVGTHWWNPPYLMPL 145
Score = 44.4 bits (100), Expect = 0.004
Identities = 20/52 (38%), Positives = 34/52 (65%)
Frame = +2
Query: 557 PLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDE 712
PLVE+V T+ VAK+ + + + G+ PV + R++ FV NR+Q+A++ E
Sbjct: 144 PLVEVVRGELTREGVAKQVSQWLSKAGKTPVDVYRDVPGFVGNRMQFALVRE 195
>UniRef50_A6ERZ1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
unidentified eubacterium SCB49|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - unidentified eubacterium SCB49
Length = 403
Score = 49.2 bits (112), Expect = 1e-04
Identities = 38/141 (26%), Positives = 63/141 (44%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
IGI+G+G +G A + A+ G V ++D+ + A ++ + L G + E KA
Sbjct: 20 IGIIGAGTMGSGIAQVAATAGCTVKLFDLNQAALDKAKASLEKIMTRLVEKGRVTEEEKA 79
Query: 301 SEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 480
Q + I L+ + + E + E+L +KKKVFQ L+S V D+ I
Sbjct: 80 RIQ-ENISYVNALKELADSDLTI-EAIIEDLGIKKKVFQELESYVSDSCIIASNTSSLSI 137
Query: 481 XXXXEGLKHKSQVIVSHPVNP 543
L+ + + H NP
Sbjct: 138 ASIASSLQKPERCVGIHFFNP 158
>UniRef50_Q9ADL9 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase;
n=7; Bacteria|Rep: Beta-hydroxybutyryl-CoA dehydrogenase
- Polyangium cellulosum (Sorangium cellulosum)
Length = 293
Score = 48.8 bits (111), Expect = 2e-04
Identities = 39/150 (26%), Positives = 64/150 (42%), Gaps = 3/150 (2%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
+G+VG+G++G A A G+ V + DV + A I+ L + G + +A
Sbjct: 12 VGVVGAGVMGVGVAQSLAQTGHDVVLVDVSEAALARARMGIRNGLRAVTLFGSAEDKKRA 71
Query: 301 SEQ---FQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 471
+ + + +TD + GA FV E V E D+K++V+ L+ V I
Sbjct: 72 GDPKAVLERVAFTTDY-GRLAGADFVVENVTEKWDIKREVYARLEGVCRPEIIFAADTSA 130
Query: 472 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
K SQV+ H +NP P+
Sbjct: 131 ISITRIGSVTKRPSQVVGMHFMNPVPLKPM 160
>UniRef50_A4FKS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Actinomycetales|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Saccharopolyspora erythraea
(strain NRRL 23338)
Length = 303
Score = 48.8 bits (111), Expect = 2e-04
Identities = 42/150 (28%), Positives = 67/150 (44%), Gaps = 5/150 (3%)
Frame = +1
Query: 127 IVGSGLIGRSWAMLFASVGYQVTVYDV---VAKQITDAIEDIKYQLHTLENDGLLRGELK 297
+VG+G IG WA LF++ G +V + D +A + DA+ + + + D LL G
Sbjct: 1 MVGAGTIGLGWAALFSAHGLEVRITDPRDDLASVVGDAMPLLAESMGR-DPDQLLAG--- 56
Query: 298 ASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 477
I+ + L AV A VQE PE L+ K+ +F ++ +
Sbjct: 57 -------IEIADSLADAVSDADLVQENGPERLEFKQDLFADIARHAPPRAVLASSSSGIV 109
Query: 478 XXXXXEGLKH--KSQVIVSHPVNPPYYVPL 561
E L +++++HP NPP VPL
Sbjct: 110 ASAIAEHLPDDVAGRLLIAHPFNPPQVVPL 139
Score = 44.8 bits (101), Expect = 0.003
Identities = 21/52 (40%), Positives = 30/52 (57%)
Frame = +2
Query: 557 PLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDE 712
PLVEIVP T+ V + +G+ PV L +E+ FV NR+Q A++ E
Sbjct: 138 PLVEIVPGERTEERVTEAATAFYTALGKTPVRLRKEVPGFVANRLQSAVMRE 189
>UniRef50_A3M445 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Acinetobacter baumannii ATCC 17978|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Acinetobacter
baumannii (strain ATCC 17978 / NCDC KC 755)
Length = 233
Score = 48.8 bits (111), Expect = 2e-04
Identities = 20/66 (30%), Positives = 33/66 (50%)
Frame = +1
Query: 364 FVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXXEGLKHKSQVIVSHPVNP 543
F+QE PE LDLK+ ++Q + S + T+ + H ++ + HP NP
Sbjct: 6 FIQENAPERLDLKQNLYQEITSYCPEKTLIASSSSGLKVSDFQKDATHPERIFLGHPFNP 65
Query: 544 PYYVPL 561
P+ +PL
Sbjct: 66 PHLLPL 71
Score = 48.0 bits (109), Expect = 3e-04
Identities = 23/59 (38%), Positives = 35/59 (59%)
Frame = +2
Query: 542 HLITYPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEVW 718
HL+ PLVEIV T P++ KK E + +G+ P+ L +E+ V NR+Q A+ E +
Sbjct: 67 HLL--PLVEIVGGKLTDPQILKKASEFYQSLGKHPIVLNKEVKGHVANRLQAALWREAF 123
>UniRef50_A0JTB4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 333
Score = 48.8 bits (111), Expect = 2e-04
Identities = 37/160 (23%), Positives = 69/160 (43%), Gaps = 1/160 (0%)
Frame = +1
Query: 82 STVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHT 261
+T ++ + KI +VGSG +G A + A G +V + DV A+ + + +
Sbjct: 9 TTAASSAANSARKIAVVGSGYMGGGIAQVLALGGARVALADVSAEVAQSNYDRLLAESDQ 68
Query: 262 LENDGLL-RGELKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVD 438
DGL G + +Q + + D+E AV A F++E VPE + +K + + +
Sbjct: 69 FVADGLFPAGSTEILKQN--LWAARDIEEAVADADFIEEAVPEIIAIKHQTLARISAAAR 126
Query: 439 DNTIXXXXXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVP 558
+ I E + + + + H NP ++P
Sbjct: 127 PDAIIGSNTSTISIADLSEPVTNPERFLGVHFSNPSPFIP 166
Score = 38.7 bits (86), Expect = 0.20
Identities = 18/52 (34%), Positives = 30/52 (57%)
Frame = +2
Query: 557 PLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDE 712
P VEI+P T R+++ G+Q ++ +++ FVLNR+QYA+ E
Sbjct: 166 PGVEIIPHAGTSATTVGAVRDLVHAAGKQ-TAVVKDVTGFVLNRLQYALFHE 216
>UniRef50_Q4PFL4 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 344
Score = 48.8 bits (111), Expect = 2e-04
Identities = 40/123 (32%), Positives = 60/123 (48%), Gaps = 8/123 (6%)
Frame = +1
Query: 82 STVIMASKFKSEKIGIVGSGLIGRSWAMLFASVG-YQVTVYDVVAKQITDAIEDIKYQLH 258
ST ++ +K + I + G+GL+G A + A G + VT+ DV K + + I L
Sbjct: 32 STSLVQNK-DVQNITVFGAGLMGAGIAQVLAHKGKFNVTLSDVTDKALANGQTIISKSLG 90
Query: 259 TLENDGLLRGELKASEQFQCIKG-------STDLETAVKGAIFVQECVPENLDLKKKVFQ 417
+ + E A EQ Q +KG +TD E AVK V E + EN+ +KK +F
Sbjct: 91 RIVKKSM--AEASAEEQAQYVKGIVDSIKVTTDPEAAVKDTDLVIEAIIENVGIKKDLFG 148
Query: 418 NLD 426
LD
Sbjct: 149 FLD 151
>UniRef50_Q2UUZ5 Cluster: RIB40 genomic DNA, SC009; n=4;
Trichocomaceae|Rep: RIB40 genomic DNA, SC009 -
Aspergillus oryzae
Length = 337
Score = 48.8 bits (111), Expect = 2e-04
Identities = 44/160 (27%), Positives = 64/160 (40%), Gaps = 13/160 (8%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG-ELK 297
+ I+G+G+IG SW LF + G +V V D + + Q TL GL G LK
Sbjct: 12 VAIIGTGVIGASWTALFLARGLKVLVTDPAPNAEKNLETYLNAQWPTLTQIGLSEGASLK 71
Query: 298 -------ASEQFQCIKGSTDLETAVK--GAIF--VQECVPENLDLKKKVFQNLDSVVDDN 444
F+ I ++ G I V + PE L+ K+ +F LD
Sbjct: 72 NYAFVDSLDNHFEEIDFIQEVPFPFSNTGVILLTVTKNGPERLEFKRTLFAYLDEKARPE 131
Query: 445 TIXXXXXXXXXXXXXXEGLKHKSQ-VIVSHPVNPPYYVPL 561
I +H + V+V HP NPP+ +PL
Sbjct: 132 VIIASSSSGIPSSEYASACRHHPERVLVGHPFNPPHLIPL 171
Score = 42.7 bits (96), Expect = 0.012
Identities = 24/60 (40%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
Frame = +2
Query: 542 HLITYPLVEIVPAPWTKPE-VAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEVW 718
HLI PLVE+VP T E V + E +G++PV + +EI F+ NR+Q A+ E +
Sbjct: 167 HLI--PLVEVVPHRTTDRETVVPRAMEFYRSLGKKPVLIQKEIPGFIANRLQAALSMEAY 224
>UniRef50_Q2S2J8 Cluster: Fatty oxidation complex, alpha subunit;
n=2; Bacteria|Rep: Fatty oxidation complex, alpha
subunit - Salinibacter ruber (strain DSM 13855)
Length = 719
Score = 48.4 bits (110), Expect = 2e-04
Identities = 35/149 (23%), Positives = 67/149 (44%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
+ +G++G+GL+G A + A G V + D + + I + E+ G++
Sbjct: 319 DTVGVLGAGLMGSGIAQVSAQNGLDVVLTDQSLALAAEGKKAIWSAVTEQEDKGIIN-TF 377
Query: 295 KASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 474
+ + + + D ++ A V E VPE+L +K V +++VVD +T+
Sbjct: 378 TRDQIVERVAPTADY-APLQAADVVIEAVPEDLSIKHAVLSEVETVVDADTVLASNTSAL 436
Query: 475 XXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
EG+ S+V+ H +P +PL
Sbjct: 437 PISTIAEGVDDPSRVLGMHYFSPVPDIPL 465
>UniRef50_A3YFA8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Marinomonas sp. MED121|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Marinomonas sp. MED121
Length = 545
Score = 48.0 bits (109), Expect = 3e-04
Identities = 36/149 (24%), Positives = 64/149 (42%), Gaps = 2/149 (1%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
IG+VG+G +G A + + G++V +YD Q +A K + L N + +G +
Sbjct: 17 IGVVGAGAMGAGIAQVASQAGHKVFLYD----QNEEASFRAKESISLLLNKKVAKGTITR 72
Query: 301 SEQFQCIKGSTDLET--AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 474
CI L + +K A + E + E L++K+ +F+ L+ + I
Sbjct: 73 EHYDTCIANIIPLHSLDELKSADLIIEAIVETLEIKQSLFRALELICKPECILASNTSSI 132
Query: 475 XXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
LK+ + + H NP +PL
Sbjct: 133 SITAIASCLKYPERFLGLHFFNPAPVMPL 161
>UniRef50_A0JVH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=12; Actinomycetales|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Arthrobacter sp. (strain FB24)
Length = 723
Score = 47.6 bits (108), Expect = 4e-04
Identities = 36/149 (24%), Positives = 67/149 (44%), Gaps = 1/149 (0%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFA-SVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
K+G+VG+GL+ A+LFA + V + D+ ++ + + ++ + + +
Sbjct: 350 KVGVVGAGLMASQLALLFARQLKVPVVMTDIDQARVDKGVGYVHAEVDKMLAKKRISAD- 408
Query: 295 KASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 474
A+ + GS + A A FV E V E L++KK+VF ++++V I
Sbjct: 409 AANRTKALVTGSVS-KDAFADADFVIEAVFEELNVKKQVFAEVEAIVSPECILATNTSSL 467
Query: 475 XXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
L H +++ H NP +PL
Sbjct: 468 SVTAMAADLAHPERLVGFHFFNPVAVMPL 496
>UniRef50_O44608 Cluster: Hydroxy-acyl-coa dehydrogenase protein 1;
n=2; Caenorhabditis|Rep: Hydroxy-acyl-coa dehydrogenase
protein 1 - Caenorhabditis elegans
Length = 299
Score = 47.6 bits (108), Expect = 4e-04
Identities = 32/115 (27%), Positives = 52/115 (45%), Gaps = 7/115 (6%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK- 297
+ I G+G++G A + GY V +Y K++ +A E IK L + + ++
Sbjct: 13 VAIFGAGMMGSGIAQVCLQAGYPVNLYGRSEKKLLEARETIKKNLIRVASKKKTDVPMEP 72
Query: 298 ------ASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDN 444
A Q ++ TD+ +A + A E V ENLDLK +FQ + N
Sbjct: 73 AALEEIAQIQLDLLQIHTDIPSAAEDAAMAIEAVAENLDLKLDIFQTIQKTCPQN 127
>UniRef50_Q02A28 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Solibacter usitatus Ellin6076|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Solibacter usitatus (strain Ellin6076)
Length = 309
Score = 47.2 bits (107), Expect = 6e-04
Identities = 37/145 (25%), Positives = 63/145 (43%)
Frame = +1
Query: 127 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASE 306
++G+G++G A+ A G Q T+ + + + +L + L+ EL A+
Sbjct: 8 VIGTGMMGPGIALTLALGGVQTTLLSRTPAGAERGVAEAR-RLGRV----LVEQELAAAL 62
Query: 307 QFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXX 486
I GSTD E ++ A V E PE + K+++F +D V + +
Sbjct: 63 DLD-IAGSTDFEYSIGQADIVIESGPEEMGWKQELFARMDRVARADAVLASNTSGLSVTA 121
Query: 487 XXEGLKHKSQVIVSHPVNPPYYVPL 561
QV+ +H NPP+ VPL
Sbjct: 122 IAAECARPEQVLATHFWNPPHLVPL 146
Score = 35.5 bits (78), Expect = 1.8
Identities = 20/57 (35%), Positives = 31/57 (54%)
Frame = +2
Query: 542 HLITYPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDE 712
HL+ PLVEI+ T P A RE++ G+ PV + + + NR+Q A++ E
Sbjct: 142 HLV--PLVEIIQGRATSPAAAAAVRELLTACGKTPVVVKLDRPGQLGNRLQMALVRE 196
>UniRef50_Q84T13 Cluster: L-3-hydroxyacyl-CoA dehydrogenase subunit
precursor; n=1; Euglena gracilis|Rep:
L-3-hydroxyacyl-CoA dehydrogenase subunit precursor -
Euglena gracilis
Length = 320
Score = 47.2 bits (107), Expect = 6e-04
Identities = 38/148 (25%), Positives = 62/148 (41%), Gaps = 7/148 (4%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG---- 288
+G+VG G +G A + A+ GY+V D+ A ++ I+ ++ L + + G
Sbjct: 25 VGVVGMGAMGHGIAQMTAAAGYKVVAVDIDANMLSKGIKAVEDSLSKVAAKAVKDGKADK 84
Query: 289 ---ELKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXX 459
E A++ I S D+ A+ V E + E+L++KKK F +L V N I
Sbjct: 85 ATAEKNAADVRSRITTSGDI-GALSSCDLVIESIIEDLNIKKKFFADLGKVAGANAILAS 143
Query: 460 XXXXXXXXXXXEGLKHKSQVIVSHPVNP 543
E S + H NP
Sbjct: 144 NTSSFPITQLGEASGRTSNFLGLHFFNP 171
>UniRef50_Q0RVG8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 288
Score = 46.8 bits (106), Expect = 7e-04
Identities = 22/52 (42%), Positives = 31/52 (59%)
Frame = +2
Query: 557 PLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDE 712
PLVE+VP+P T+P+V + G+ V L RE FV NR+Q A++ E
Sbjct: 127 PLVEVVPSPDTRPDVVSAVTSALVAAGKTVVPLNREAPGFVANRLQAALVRE 178
Score = 42.3 bits (95), Expect = 0.016
Identities = 35/150 (23%), Positives = 69/150 (46%)
Frame = +1
Query: 112 SEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGE 291
+ +I + G+G++GR A++ A G++V++YD A D+ +
Sbjct: 3 ASQISVFGAGIMGRGIAVVLADAGHRVSLYDARA--------DVARE------------- 41
Query: 292 LKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 471
A+ I+ S +E AV+G+ + E V ENL++K+ +F ++ ++T
Sbjct: 42 --AAAAHPNIEASDTIEAAVEGSSLLFEAVVENLEVKRDLFAEIER-FSESTPIASNTST 98
Query: 472 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
+ L +++++H NP VPL
Sbjct: 99 FTPSELAKNLCEPGRLVIAHFFNPAEVVPL 128
>UniRef50_Q876X5 Cluster: Dehydrogenase; n=7; Pezizomycotina|Rep:
Dehydrogenase - Fusarium sporotrichioides
Length = 285
Score = 46.8 bits (106), Expect = 7e-04
Identities = 34/110 (30%), Positives = 54/110 (49%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
+ ++G G++GR A +A+ GY V + D +Q A+E + D +RG ++A
Sbjct: 14 VAVLGGGVLGRRIACGWAASGYDVIIRDPSHEQRVAAVEYCNTSMSKYP-DSNVRGSIQA 72
Query: 301 SEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTI 450
E DL AV A V E VPE L +K F +L+ + ++TI
Sbjct: 73 VE---------DLPEAVAKAWLVIETVPEKLPIKIATFTDLERLTSEDTI 113
>UniRef50_Q47M90 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5;
root|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Thermobifida fusca (strain YX)
Length = 398
Score = 46.4 bits (105), Expect = 0.001
Identities = 35/110 (31%), Positives = 54/110 (49%), Gaps = 4/110 (3%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDA-IEDIKYQLHTLENDGLLRGEL 294
K+G+VG G +G +FA G+ VT +I DA +E + L + +G+L
Sbjct: 7 KVGVVGLGTMGAGIVEVFARAGFTVT-----GVEIDDAALERGRTHLEKSLAKAVAKGKL 61
Query: 295 KASEQFQCIKGSTDLETA---VKGAIFVQECVPENLDLKKKVFQNLDSVV 435
EQ + I G T+ + A E VPE LD+K+ VF +LD ++
Sbjct: 62 TEDEQ-RAILGRVTFTTSRDDLADAHLAVEAVPERLDIKRSVFADLDRIL 110
>UniRef50_Q7RZ80 Cluster: Putative uncharacterized protein
NCU04393.1; n=2; Sordariales|Rep: Putative
uncharacterized protein NCU04393.1 - Neurospora crassa
Length = 420
Score = 46.4 bits (105), Expect = 0.001
Identities = 44/157 (28%), Positives = 66/157 (42%), Gaps = 17/157 (10%)
Frame = +1
Query: 127 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDI-----KYQLHTLENDGL---- 279
I+G+G IGR A+++AS VTVYD+ + + E I KY L + G
Sbjct: 97 IMGAGHIGRRVALVWASALRPVTVYDISKNALRSSTEYITDNLAKYCLEHGTHPGPVHFT 156
Query: 280 --LRGELKASEQ------FQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVV 435
LR A ++ F + T KG V EC+PENL LK ++ ++
Sbjct: 157 SDLREATTAGKRHGLKLDFSAAHDTEPKSTRKKGPWMVIECLPENLSLKIAALAEIERLL 216
Query: 436 DDNTIXXXXXXXXXXXXXXEGLKHKSQVIVSHPVNPP 546
+N I L+H ++I +H PP
Sbjct: 217 PENCIIASNSSSLMTSEMAPHLQHPGRLINTHYYIPP 253
>UniRef50_A2QA05 Cluster: Catalytic activity:; n=4;
Trichocomaceae|Rep: Catalytic activity: - Aspergillus
niger
Length = 622
Score = 46.4 bits (105), Expect = 0.001
Identities = 33/105 (31%), Positives = 49/105 (46%)
Frame = +1
Query: 109 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG 288
KS I I+G+G++GR A +F+S GY V + D + A I +H + R
Sbjct: 13 KSRPIVIIGAGILGRRIAAVFSSAGYSVHISDPSPSALDSARTYISTHIHEFTTH-IPRP 71
Query: 289 ELKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNL 423
L I T + AV A + E VPE L +K+ +F +L
Sbjct: 72 SLSPGP----ISTFTSVPEAVATAWLIVEAVPEILPIKQSLFADL 112
>UniRef50_Q7D836 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=8; Mycobacterium tuberculosis complex|Rep:
3-hydroxyacyl-CoA dehydrogenase family protein -
Mycobacterium tuberculosis
Length = 304
Score = 46.0 bits (104), Expect = 0.001
Identities = 41/148 (27%), Positives = 67/148 (45%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 297
+ +VG+GL+GR A + AS G V + D A+ + A + G RG +
Sbjct: 9 RAAVVGAGLMGRRIAGVLASAGLDVAITDTNAEILHAA------AVEAARVAGAGRGSVA 62
Query: 298 ASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 477
A + DL A+ A V E V ENL +K+++F+ L ++ D +
Sbjct: 63 A---------AADLAAAIPDADLVIEAVVENLAVKQELFERLATLAPD-AVLATNTSVLP 112
Query: 478 XXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
E ++ S+VI +H NPP +P+
Sbjct: 113 IGAVTERVEDGSRVIGTHFWNPPDLIPV 140
Score = 46.0 bits (104), Expect = 0.001
Identities = 18/52 (34%), Positives = 35/52 (67%)
Frame = +2
Query: 557 PLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDE 712
P+VE+VP+ T P+ A + ++ ++G+ PV + R++ F+ NR+Q+A+ E
Sbjct: 139 PVVEVVPSARTAPDTADRVVALLTQVGKLPVRVGRDVPGFIGNRLQHALWRE 190
>UniRef50_Q3A7N5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Pelobacter carbinolicus DSM 2380|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Pelobacter carbinolicus (strain DSM 2380
/ Gra Bd 1)
Length = 304
Score = 46.0 bits (104), Expect = 0.001
Identities = 35/108 (32%), Positives = 50/108 (46%)
Frame = +1
Query: 127 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASE 306
+VG G +GR A A+ GY VT+YD+ A+ + + I L +G ++ + A
Sbjct: 11 VVGGGTMGRQIAFQCAAHGYFVTIYDISAEVLQATQKRIGAYADYLVAEGHIQPQ-AAKR 69
Query: 307 QFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTI 450
I STD A A + E VPE+ LK +VF D TI
Sbjct: 70 AINRISISTDARQAA-NADLLCEAVPEDPALKGEVFARFDRYCPQRTI 116
>UniRef50_P45856 Cluster: Probable 3-hydroxybutyryl-CoA
dehydrogenase; n=65; Bacteria|Rep: Probable
3-hydroxybutyryl-CoA dehydrogenase - Bacillus subtilis
Length = 287
Score = 46.0 bits (104), Expect = 0.001
Identities = 38/143 (26%), Positives = 60/143 (41%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
++I + G+G +G A A G+ V +YDV + ++ +K QL G R E
Sbjct: 4 KQIMVAGAGQMGSGIAQTAADAGFYVRMYDVNPEAAEAGLKRLKKQLARDAEKG-KRTET 62
Query: 295 KASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 474
+ I S LE A + A V E + EN+ K ++F+ LD + +TI
Sbjct: 63 EVKSVINRISISQTLEEA-EHADIVIEAIAENMAAKTEMFKTLDRICPPHTILASNTSSL 121
Query: 475 XXXXXXEGLKHKSQVIVSHPVNP 543
+VI H +NP
Sbjct: 122 PITEIAAVTNRPQRVIGMHFMNP 144
>UniRef50_A1SPQ6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3;
Actinomycetales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Nocardioides sp. (strain BAA-499 / JS614)
Length = 287
Score = 45.6 bits (103), Expect = 0.002
Identities = 22/53 (41%), Positives = 31/53 (58%)
Frame = +2
Query: 563 VEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEVWR 721
VE+VP P T + +++E +G+ PV L +EI FV NRI A+ DE R
Sbjct: 152 VEVVPGPETSGQTVASCVDLVESLGKVPVVLEKEIPGFVANRILNAVRDEAIR 204
Score = 41.5 bits (93), Expect = 0.028
Identities = 28/109 (25%), Positives = 53/109 (48%), Gaps = 1/109 (0%)
Frame = +1
Query: 127 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQL-HTLENDGLLRGELKAS 303
+VG+G +G AM+ A G+QV ++DV + A +++ ++ +E ++ A+
Sbjct: 6 VVGAGAMGSQIAMVCALAGHQVCLHDVDPAMLERADRELRDRMARQVEKGRRTADDVTAA 65
Query: 304 EQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTI 450
+ + S A A V E V E +++K ++F LD + TI
Sbjct: 66 FERLRVADSLAAAAAAADADLVIEAVVERIEVKSELFAELDRLCPPATI 114
>UniRef50_A4RUY4 Cluster: Predicted protein; n=5; cellular
organisms|Rep: Predicted protein - Ostreococcus
lucimarinus CCE9901
Length = 722
Score = 45.6 bits (103), Expect = 0.002
Identities = 34/149 (22%), Positives = 66/149 (44%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
+ +G+VG GL+G A G QV + ++ + + + I+ L ++ G + E
Sbjct: 305 KSVGVVGGGLMGSGIATACLLAGIQVVLKEIKQEFLDAGVGRIQSNLTSMVRKGRMT-ED 363
Query: 295 KASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 474
KA + +K T + + V E V ENL LK+K+F L+ + + I
Sbjct: 364 KARQLMSLVK-PTLTDQDFRQCDMVIEAVIENLPLKQKIFCELERICKPDCILSTNTSTI 422
Query: 475 XXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
+K+ +++ +H +P + + L
Sbjct: 423 DITKIAAKMKNPERIVGAHFFSPAHVMQL 451
>UniRef50_P45364 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=13;
Clostridia|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Clostridium difficile
Length = 281
Score = 45.6 bits (103), Expect = 0.002
Identities = 36/142 (25%), Positives = 58/142 (40%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 297
K+ ++GSG +G FAS G+ V + I + + L L G K
Sbjct: 2 KLAVIGSGTMGSGIVQTFASCGHDVCLKSRTQGAIDKCLALLDKNLTKLVTKGKWMKATK 61
Query: 298 ASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 477
A E + +T+ E +K + E E++++KK VF+ LD + ++TI
Sbjct: 62 A-EILSHVSSTTNYED-LKDMDLIIEASVEDMNIKKDVFKLLDELCKEDTILATNTSSLS 119
Query: 478 XXXXXEGLKHKSQVIVSHPVNP 543
K +VI H NP
Sbjct: 120 ITEIASSTKRPDKVIGMHFFNP 141
>UniRef50_Q9RUA4 Cluster: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA
isomerase/3-hydroxyacyl-CoA dehydrogenase; n=18;
Bacteria|Rep: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA
isomerase/3-hydroxyacyl-CoA dehydrogenase - Deinococcus
radiodurans
Length = 708
Score = 45.2 bits (102), Expect = 0.002
Identities = 28/109 (25%), Positives = 51/109 (46%)
Frame = +1
Query: 124 GIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKAS 303
GI+G+G +G AM F +VG VT+ + + + + I+ G + +
Sbjct: 311 GIIGAGTMGGGIAMNFLNVGIPVTIVETSQEALDRGLGVIRKNYENTAKKGRMTQD-DVE 369
Query: 304 EQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTI 450
++ + + +E + GA + E V EN+D+KK +F LD + I
Sbjct: 370 KRMGLLTPTLKMED-LAGADIIIEAVFENMDVKKDIFTRLDKIAKPGAI 417
>UniRef50_Q1D1F2 Cluster: Fatty oxidation complex, alpha subunit
FadJ; n=2; Cystobacterineae|Rep: Fatty oxidation
complex, alpha subunit FadJ - Myxococcus xanthus (strain
DK 1622)
Length = 746
Score = 45.2 bits (102), Expect = 0.002
Identities = 39/151 (25%), Positives = 68/151 (45%), Gaps = 2/151 (1%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASV-GYQVTVYDVVAKQITDAIEDIKYQL-HTLENDGLLRG 288
+K+ ++G GL+G A + + + G V V D + A++ ++ L ++ L R
Sbjct: 350 KKVAVLGGGLMGGGIAYVTSVLQGVPVRVKDKDDAGVGRAMKQVQSILDERVKRRSLTRR 409
Query: 289 ELKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXX 468
E A + TD + K A V E V E+L LK ++ +++V D TI
Sbjct: 410 EATAKSAL--VTAGTDY-SGFKSADLVIEAVFEDLKLKHRIIAEVEAVTGDQTIFASNTS 466
Query: 469 XXXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
+G + +QVI H +P + +PL
Sbjct: 467 SIPITELAKGSRRPAQVIGMHYFSPVHKMPL 497
>UniRef50_Q2VHK2 Cluster: Oxidoreductase; n=11; Lactobacillales|Rep:
Oxidoreductase - Lactococcus lactis
Length = 449
Score = 44.8 bits (101), Expect = 0.003
Identities = 29/74 (39%), Positives = 40/74 (54%), Gaps = 1/74 (1%)
Frame = +1
Query: 64 SCGTVASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDI 243
S V ST +M K E + I+GSG IG +A +FAS G +VTV D+ + EDI
Sbjct: 146 SRNVVTSTELMDLKQLPEHLTIIGSGYIGLEFASMFASYGSKVTVLDIFDNFLPRDDEDI 205
Query: 244 -KYQLHTLENDGLL 282
K LE+ G++
Sbjct: 206 SKLVRSDLESRGII 219
>UniRef50_Q0UJN7 Cluster: Predicted protein; n=1; Phaeosphaeria
nodorum|Rep: Predicted protein - Phaeosphaeria nodorum
(Septoria nodorum)
Length = 152
Score = 44.8 bits (101), Expect = 0.003
Identities = 37/143 (25%), Positives = 61/143 (42%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
+ +GIVG+G+IG SW LF + G +V V D + +K TL++ G +
Sbjct: 4 QTVGIVGTGVIGASWTGLFLAHGLRVLVADPAPGAKEKLEKHLKAIWPTLQSIGTKKSAS 63
Query: 295 KASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 474
A+ F G++ + K A PE +LK+ + +DS V + +
Sbjct: 64 LANYTF---VGASLGQHYKKNA-------PERQNLKQSLLAEIDSSVRSDVVIASSSSGI 113
Query: 475 XXXXXXEGLKHKSQVIVSHPVNP 543
K +V++ HP NP
Sbjct: 114 PSSRFISKCKTPERVLIGHPFNP 136
>UniRef50_Q5LKF7 Cluster: Fatty oxidation complex, alpha subunit;
n=5; Bacteria|Rep: Fatty oxidation complex, alpha
subunit - Silicibacter pomeroyi
Length = 714
Score = 44.4 bits (100), Expect = 0.004
Identities = 37/153 (24%), Positives = 66/153 (43%), Gaps = 2/153 (1%)
Frame = +1
Query: 109 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG 288
K +++GI+G+G++G+ A A+ G V + D Q +A E K TL + + +G
Sbjct: 316 KVQRLGILGAGMMGQGIAFSAATAGLPVVLKD----QTLEAAERGKAYTATLLDKRVKQG 371
Query: 289 ELKASEQ--FQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXX 462
+ A E+ + TD +KG + E V E +D+K V ++++ +N I
Sbjct: 372 RMSAEEREAVLALITPTDKADDLKGCDLIIEAVFEKIDIKDAVLAEHEALLAENGIWGSN 431
Query: 463 XXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
G + H +P +PL
Sbjct: 432 TSTLPITRLATGATRPENFVGLHFFSPVDKMPL 464
>UniRef50_Q0LZ25 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Caulobacter sp. K31|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Caulobacter sp. K31
Length = 296
Score = 44.4 bits (100), Expect = 0.004
Identities = 21/54 (38%), Positives = 36/54 (66%)
Frame = +2
Query: 560 LVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEVWR 721
LVE+VPA T PE T +++ IG+QP+++ +++ F +NR+ +A+L E R
Sbjct: 164 LVEVVPAFETSPETVAWTTSLLKRIGKQPIAV-KDVPGFAVNRMLHAMLIEAVR 216
Score = 40.7 bits (91), Expect = 0.048
Identities = 38/113 (33%), Positives = 59/113 (52%), Gaps = 4/113 (3%)
Frame = +1
Query: 100 SKFKSE-KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDG 276
S F E KIG+VG+GL+G A++FA G V ++D A A+E +L L + G
Sbjct: 10 SPFAPELKIGVVGAGLMGAEIALVFALGGMDVLLHDRDAA----ALEKALARLSALLDRG 65
Query: 277 LLRG---ELKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLD 426
+ RG E + + + I+ + DL + V E V E+L++K +V LD
Sbjct: 66 VSRGLYTEGRRATALENIRLAPDL-SRFGDRDLVTEAVFESLEVKGQVLAALD 117
>UniRef50_A4FGV2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Actinomycetales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Saccharopolyspora erythraea (strain NRRL 23338)
Length = 517
Score = 44.4 bits (100), Expect = 0.004
Identities = 32/141 (22%), Positives = 59/141 (41%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
+ ++G+G++GR A L A+ G V + D + ++ A++ + L G + E +A
Sbjct: 11 VRVIGTGVMGRGIAQLAAAAGLTVELADARQEAVSAAVDHVGEMFGKLVGKGRMSAE-EA 69
Query: 301 SEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 480
++ D V E V E+LD K+++F L+ V + +
Sbjct: 70 DAATARLRPVGDPLAPADSCDLVVEAVREDLDTKRELFAGLEEVCPRHAVLATNTSSLSV 129
Query: 481 XXXXEGLKHKSQVIVSHPVNP 543
L S++I H NP
Sbjct: 130 TAIGAALADPSRLIGLHFFNP 150
>UniRef50_A5VHQ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=2; Lactobacillus reuteri|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Lactobacillus reuteri F275
Length = 294
Score = 44.0 bits (99), Expect = 0.005
Identities = 35/113 (30%), Positives = 57/113 (50%), Gaps = 1/113 (0%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
+ I I G+G++G A A G+ V+VY+ I A IK E D L +
Sbjct: 2 KNIMIAGAGVLGSQIAYQTALSGFNVSVYN---HHIDTAERRIKALKSDYERD-LHLTDK 57
Query: 295 KASEQFQCIKGSTD-LETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTI 450
+ + IK TD + TAVK A + E +PE+L+LK++ ++ + + + TI
Sbjct: 58 EFQQGLNNIKVITDDVATAVKDADLMIEALPESLELKEQFYEEVSELAPEKTI 110
>UniRef50_A4SW21 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=1; Polynucleobacter sp.
QLW-P1DMWA-1|Rep: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor - Polynucleobacter sp.
QLW-P1DMWA-1
Length = 310
Score = 44.0 bits (99), Expect = 0.005
Identities = 20/53 (37%), Positives = 35/53 (66%)
Frame = +2
Query: 557 PLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEV 715
PLVE+V + PE+AK ++ + ++PV + ++I F+ NRIQ+A++ EV
Sbjct: 142 PLVEVVLGKTSDPELAKTVCQLFQAHHKKPVLVKKDIPGFLANRIQHALMREV 194
>UniRef50_A1SEZ9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Nocardioides sp. JS614|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 275
Score = 44.0 bits (99), Expect = 0.005
Identities = 41/150 (27%), Positives = 65/150 (43%)
Frame = +1
Query: 112 SEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGE 291
S + +VG G +GR A+ + G++VT+ D VA+ + D + + H + RG
Sbjct: 2 STSMVVVGGGTMGRGIAIAALATGFEVTLVD-VAEDVLDRAQ-ARVSEHFARHPQPDRGV 59
Query: 292 LKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 471
L +T L +++ A V E VPE L LK ++FQ L T+
Sbjct: 60 LHT---------TTSLAGSLETAEVVIEAVPEILPLKTQIFQQLRG-APPGTLLVSNTST 109
Query: 472 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
E S+V+ H NP + +PL
Sbjct: 110 MSISALAEACGGSSRVVGMHFFNPAHRMPL 139
>UniRef50_A0Z5J4 Cluster: Enoyl-CoA hydratase; n=2; unclassified
Gammaproteobacteria (miscellaneous)|Rep: Enoyl-CoA
hydratase - marine gamma proteobacterium HTCC2080
Length = 699
Score = 44.0 bits (99), Expect = 0.005
Identities = 35/135 (25%), Positives = 58/135 (42%), Gaps = 2/135 (1%)
Frame = +1
Query: 34 SLRF*FTRGLSCGTVASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVA 213
+LR F + G + S +GI+G+G +G AM FA G VT+ D+
Sbjct: 267 ALRHMFFAERAAGKIDSLPKDTKALDIASVGIIGAGTMGGGIAMCFAQAGIAVTLVDMTD 326
Query: 214 KQITDAIEDIKYQLHTLENDGLLRGELKASEQFQCIKGSTDLET--AVKGAIFVQECVPE 387
+ + +E I + +G L ++ + T + + V E V E
Sbjct: 327 EAVKGGLEKIAKNYAI----SVKKGRLTVAQTDAILANITTSSSFDDLANVDMVIEAVFE 382
Query: 388 NLDLKKKVFQNLDSV 432
NL++KK+VF LD +
Sbjct: 383 NLEVKKEVFGKLDVI 397
>UniRef50_O29090 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 312
Score = 43.6 bits (98), Expect = 0.007
Identities = 37/148 (25%), Positives = 70/148 (47%), Gaps = 1/148 (0%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQ-LHTLENDGLLRGELK 297
I ++G+G +G + A+LFA+ G++VT+ D + A + + + L LE GL + +
Sbjct: 5 IAVIGAGTMGAAIALLFANAGFEVTLVDKSRGALRRAEDRHRGESLEELEEAGLRKQDNP 64
Query: 298 ASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 477
AS I +T+L V F+ E + E L K ++F+ ++ ++ +
Sbjct: 65 AS----LITYTTELR--VYECDFIVEAIVERLRDKIELFRKIEE-INSPAVLATNTSSFM 117
Query: 478 XXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
L + ++ + H NPP +PL
Sbjct: 118 PSEIARHLANPERLTLFHFSNPPILMPL 145
>UniRef50_Q1IIH2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5;
cellular organisms|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Acidobacteria bacterium (strain
Ellin345)
Length = 282
Score = 43.2 bits (97), Expect = 0.009
Identities = 36/145 (24%), Positives = 63/145 (43%), Gaps = 3/145 (2%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQL--HTLEND-GLLRG 288
K+G++G+G +G A +FA GY+V + DV + + + IK L +N +G
Sbjct: 5 KVGVIGAGTMGNGIAHVFAKSGYKVVLCDVKREFLDRGLATIKKNLEREVAKNKISQEQG 64
Query: 289 ELKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXX 468
++ A + ++ DL V E E ++K ++F++LDS+ + I
Sbjct: 65 QVAADHIYPTLE-RKDL----ADCDIVVEAASERFEIKAELFRDLDSICRPDVILATNTS 119
Query: 469 XXXXXXXXEGLKHKSQVIVSHPVNP 543
K +VI H NP
Sbjct: 120 SISITKIAAVTKRPDKVIGMHFFNP 144
>UniRef50_A1IFR8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Candidatus
Desulfococcus oleovorans Hxd3
Length = 304
Score = 43.2 bits (97), Expect = 0.009
Identities = 26/101 (25%), Positives = 53/101 (52%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
+K+ I+G+G +G+ L A+ G++ +YD+ + A + ++ + L GE
Sbjct: 10 KKVLILGAGSMGQQIGFLCAAKGFETAIYDLSPPLLDTAKKRLEKLAGRFVSRHRLTGE- 68
Query: 295 KASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQ 417
+A+ + + D E A A F+ E V E++++K +VF+
Sbjct: 69 EAAAAMARVTLTPDSEQAAANADFISESVTESVEIKCRVFE 109
Score = 35.5 bits (78), Expect = 1.8
Identities = 16/54 (29%), Positives = 27/54 (50%)
Frame = +2
Query: 548 ITYPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILD 709
+T +V+I+P P T PE A+ R +GQ P+ +E + N + + D
Sbjct: 152 LTSDIVDIMPHPGTTPETAETIRAFALRLGQVPIVFKKENHGYAFNALLMNLCD 205
>UniRef50_A7S4Z9 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 310
Score = 43.2 bits (97), Expect = 0.009
Identities = 37/147 (25%), Positives = 65/147 (44%), Gaps = 1/147 (0%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
+ ++G+GL+G A A G +V +YD A+ A+E K L + + L R E+ A
Sbjct: 8 VAVIGAGLMGTCIAGELAYHGARVNLYDRSAQ----AMEKSKEML-IQQKEQLKREEVMA 62
Query: 301 SEQF-QCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 477
+ F + LE AV + + E ENL++KK VF+++ N +
Sbjct: 63 TSDFIGTVAFCESLEEAVVNSGLIFEATIENLEVKKSVFKSISQFCRTNAVIATNTLALD 122
Query: 478 XXXXXEGLKHKSQVIVSHPVNPPYYVP 558
E + + + + + P Y +P
Sbjct: 123 TSVVAEHVTNPERCLGIRFLYPVYSIP 149
>UniRef50_A2QCM7 Cluster: Catalytic activity: precursor; n=5;
Trichocomaceae|Rep: Catalytic activity: precursor -
Aspergillus niger
Length = 338
Score = 43.2 bits (97), Expect = 0.009
Identities = 22/75 (29%), Positives = 37/75 (49%)
Frame = +1
Query: 337 LETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXXEGLKHKSQ 516
LE+A A VQE PEN+D K+ + +++V + ++ K++
Sbjct: 93 LESACASATIVQEQGPENVDWKQSAWARIEAVAPPSAHLWTSTSGIAASIQQAKMQDKTR 152
Query: 517 VIVSHPVNPPYYVPL 561
++V HP NPP +PL
Sbjct: 153 LLVVHPFNPPNIMPL 167
Score = 42.3 bits (95), Expect = 0.016
Identities = 24/54 (44%), Positives = 32/54 (59%), Gaps = 2/54 (3%)
Frame = +2
Query: 557 PLVEIVPAPWTKPEVAKKTREIMEEIG--QQPVSLTREIDXFVLNRIQYAILDE 712
PL+EIVPAP T E + RE G +PV + +EI FV NR+ +A+L E
Sbjct: 166 PLLEIVPAPGTSAERVEFAREYFSLPGSRHRPVVIQKEIPGFVGNRLAFALLRE 219
>UniRef50_Q1YTH7 Cluster: Fatty oxidation complex, alpha subunit;
n=4; Gammaproteobacteria|Rep: Fatty oxidation complex,
alpha subunit - gamma proteobacterium HTCC2207
Length = 718
Score = 42.7 bits (96), Expect = 0.012
Identities = 39/157 (24%), Positives = 67/157 (42%), Gaps = 1/157 (0%)
Frame = +1
Query: 94 MASKFKSEKI-GIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLEN 270
+ASK K G++G+G++G A A GY V + D+ + I++ L
Sbjct: 310 LASKLPEIKTAGVIGAGIMGGGIAYQNAIRGYSVVMKDINQPALDLGIQEANKLLAKGVK 369
Query: 271 DGLLRGELKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTI 450
G L E KA + IK S + ++ V + E V E +KK V +++++D++ +
Sbjct: 370 RGKLTEE-KAGQILSLIKPSLE-DSDVAPCNMLVEAVVELESVKKMVLPAVEALLDNSAV 427
Query: 451 XXXXXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
E L+ H NP + +PL
Sbjct: 428 ITSNTSTISINRLAESLERPQNFCGMHFFNPVHAMPL 464
>UniRef50_A6GC68 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 733
Score = 42.7 bits (96), Expect = 0.012
Identities = 39/157 (24%), Positives = 67/157 (42%), Gaps = 8/157 (5%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHT----LENDG-- 276
E++ I+G+G++G A + A GYQV + D+ + + + + QL L++ G
Sbjct: 333 ERVAILGAGMMGAGLAYICADAGYQVVLKDINQEALDKGVAHFEAQLRKRKRHLDDAGRQ 392
Query: 277 LLRGELKASEQFQCI--KGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTI 450
+R L S + + G TDL + E V ENLDLK +V + + + + I
Sbjct: 393 AIRDRLTPSLELSALSDNGGTDL---------IIEAVFENLDLKHRVTRETEPTLSADGI 443
Query: 451 XXXXXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
+ H + I H +P +PL
Sbjct: 444 WASNTSAIPIGDLAKVSAHADRFIGLHYFSPVEVMPL 480
>UniRef50_A0IJE2 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=5; Gammaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Serratia proteamaculans 568
Length = 506
Score = 42.7 bits (96), Expect = 0.012
Identities = 29/143 (20%), Positives = 63/143 (44%), Gaps = 1/143 (0%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 297
++ ++G+G +G A + A+ G+QV ++D+ A A+ + +L G + +
Sbjct: 9 RVAVIGAGTMGIGIAQVAAAAGHQVQLFDIAASAARQALGALAQRLRQRVAAG--KADAT 66
Query: 298 ASEQFQC-IKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 474
+E I+ + L + + + E V E L +K+ +F+ L+++ T+
Sbjct: 67 TTEALLARIQPAESLNSLADSGLVI-EAVAEKLAIKQSLFRELEALCSPATLFASNTSSL 125
Query: 475 XXXXXXEGLKHKSQVIVSHPVNP 543
L+H ++ H NP
Sbjct: 126 SITAIAGALQHPQRLAGLHFFNP 148
>UniRef50_UPI00006A277A Cluster: UPI00006A277A related cluster; n=1;
Xenopus tropicalis|Rep: UPI00006A277A UniRef100 entry -
Xenopus tropicalis
Length = 666
Score = 42.3 bits (95), Expect = 0.016
Identities = 35/148 (23%), Positives = 61/148 (41%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 297
K+GIVG+G +G AM FA+VG V +V + + + ++ G L E +
Sbjct: 292 KVGIVGAGTMGGGIAMNFANVGIPTVVVEVNDETLQRGLGLVRRNYEASAAKGRLTAE-Q 350
Query: 298 ASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 477
+ + ++G+ D A+ V E V EN+ LK+ + L +V I
Sbjct: 351 VAGRMALLQGALDY-AALAECDLVIEAVFENMALKQDICAKLGAVAKPGAIIATNTSTLD 409
Query: 478 XXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
+ V+ H +P + + L
Sbjct: 410 VDVLARATGRSADVVGMHFFSPAHVMRL 437
>UniRef50_Q1GGC1 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=4; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding -
Silicibacter sp. (strain TM1040)
Length = 733
Score = 42.3 bits (95), Expect = 0.016
Identities = 30/115 (26%), Positives = 61/115 (53%), Gaps = 3/115 (2%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
+KIG++G+G++G A++ A G +V + D + DA + K T + G+ RG+
Sbjct: 327 KKIGVLGAGMMGAGIALVSAQAGMEVVLID----RDQDAADKGKAYSATYMDKGIKRGKA 382
Query: 295 ---KASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTI 450
K I + DL+ A+KG + E V E+ +K ++ + +++++ ++ I
Sbjct: 383 TPEKKEALLAQITATADLD-ALKGCDLIIEAVFEDPGVKAEMTKKVEAIIPEDCI 436
>UniRef50_A6WDS7 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=1; Kineococcus radiotolerans
SRS30216|Rep: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding - Kineococcus radiotolerans SRS30216
Length = 681
Score = 42.3 bits (95), Expect = 0.016
Identities = 35/152 (23%), Positives = 67/152 (44%), Gaps = 1/152 (0%)
Frame = +1
Query: 109 KSEKIGIVGSGLIGRSWAMLFA-SVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLR 285
K +G+VG+GL+ A+L + V + DV ++ + ++ + L G +
Sbjct: 317 KVTSVGVVGAGLMASQLALLLLHRLQVPVVLTDVSPDRVEKGVGFVREGVAELLRKGRVS 376
Query: 286 GELKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXX 465
+ A+ + GS D ++A+ A FV E V E L +K+ V + L+ ++ + +
Sbjct: 377 PD-TANRLSASVSGSVD-KSALADADFVVEAVFEELAVKQDVLRELEPLLRPDAVIATNT 434
Query: 466 XXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
L+H + + H NP +PL
Sbjct: 435 SSLSVTAMASVLEHPQRFVGFHFFNPVAVLPL 466
>UniRef50_Q39NP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=54;
cellular organisms|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 284
Score = 41.9 bits (94), Expect = 0.021
Identities = 36/149 (24%), Positives = 60/149 (40%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
E +G+VG+G +G A A G V + DV + I +K L L + L
Sbjct: 4 EIVGVVGAGTMGNGIAQTAAVAGLNVVMIDVSDAALEKGIATLKGSLDRLVSKDKLDAAT 63
Query: 295 KASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 474
+ + + I STD + A V E EN++LK ++ + +++V I
Sbjct: 64 RDAALAR-ITTSTDY-AKLAAADIVIEAATENVELKGRILKQIEAVARAEAIIATNTSSI 121
Query: 475 XXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
L ++ + H NP +PL
Sbjct: 122 SITALAAPLADPARFVGMHFFNPVPLMPL 150
Score = 34.3 bits (75), Expect = 4.2
Identities = 18/54 (33%), Positives = 28/54 (51%)
Frame = +2
Query: 557 PLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEVW 718
PLVEI+ T A RE+ E + P+ + R FV+NRI +++E +
Sbjct: 149 PLVEIIRGLQTSDATASAVRELTERFDKSPIGV-RNSPGFVVNRILVPMINEAF 201
>UniRef50_Q1EVV0 Cluster: Dihydrolipoyl dehydrogenase; n=6;
Clostridium|Rep: Dihydrolipoyl dehydrogenase -
Clostridium oremlandii OhILAs
Length = 467
Score = 41.9 bits (94), Expect = 0.021
Identities = 28/103 (27%), Positives = 54/103 (52%), Gaps = 2/103 (1%)
Frame = +1
Query: 70 GTVASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKY 249
G + S +++ K +++ I+G G+IG +A +F ++G +VTV++ + +DI
Sbjct: 158 GVMTSNELLSFKEIPKRLAIIGGGVIGIEFAGIFNALGSEVTVFEFAPSILIKLDKDISK 217
Query: 250 QLHT-LENDGLLRGELKASEQFQCIKGSTDLETA-VKGAIFVQ 372
+L T L+ DG+ E+ + GS + KG+I V+
Sbjct: 218 RLTTSLKKDGIKINTSTGVEEIKESNGSLVIVAKDKKGSIEVE 260
>UniRef50_A6X670 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=1; Ochrobactrum anthropi ATCC 49188|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding -
Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 /
NCTC 12168)
Length = 659
Score = 41.9 bits (94), Expect = 0.021
Identities = 32/110 (29%), Positives = 51/110 (46%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
IGI G+GL+G A+ + GY V Y+ A+ I + + G L E A
Sbjct: 297 IGIAGTGLMGSGIAVASLAAGYTVIGYETTAEAAAKGHARITDMIQKAVDTGRLSTE-AA 355
Query: 301 SEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTI 450
Q + S D+ A+ A V E V ++ +K +F+ LD+++ TI
Sbjct: 356 DAQRSKLSVSADM-AALADADLVIEAVFDDFTVKASLFRELDALLPPATI 404
>UniRef50_Q4Q939 Cluster: Trifunctional enzyme alpha subunit,
mitochondrial-like protein; n=6; Trypanosomatidae|Rep:
Trifunctional enzyme alpha subunit, mitochondrial-like
protein - Leishmania major
Length = 726
Score = 41.9 bits (94), Expect = 0.021
Identities = 32/151 (21%), Positives = 62/151 (41%), Gaps = 3/151 (1%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQL-HTLENDGLLRGEL 294
++G++G+G++G FA V V D+ + + I +++ + + ++ EL
Sbjct: 309 RVGVIGAGVMGSGIVHYFAKNNIPVAVKDLTEESVKQGITNVRAEFERAVRRKRMVTAEL 368
Query: 295 KASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNL--DSVVDDNTIXXXXXX 468
+ + G T E + A + E E +D+KKKV Q L D ++ ++
Sbjct: 369 DG--KMALVTGGTTNE-VFRDADVIVEAAVEVMDIKKKVIQQLEKDGILHSKSLFATNTS 425
Query: 469 XXXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
K ++ H NP +PL
Sbjct: 426 SLSLTEMQTVAKCPHNIVGMHFFNPVSKMPL 456
>UniRef50_A0HAN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Comamonas testosteroni KF-1
Length = 706
Score = 41.5 bits (93), Expect = 0.028
Identities = 32/111 (28%), Positives = 53/111 (47%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 297
++GI+G+G +G AM FA+ G V + + + + I+ + G L E
Sbjct: 307 RVGILGAGTMGGGIAMAFANAGIPVVLCEREQAALDRGMAMIERNYQISVSRGGLTAE-A 365
Query: 298 ASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTI 450
E+ Q I+ + DL +A V E V E++ +K+ VF LD + TI
Sbjct: 366 VKERMQHIQQTLDL-SAFAEVDLVIEAVFEDMAIKRDVFVQLDRICRKGTI 415
>UniRef50_Q5LVG3 Cluster: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase;
n=2; Rhodobacteraceae|Rep: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase -
Silicibacter pomeroyi
Length = 681
Score = 41.1 bits (92), Expect = 0.037
Identities = 38/150 (25%), Positives = 63/150 (42%), Gaps = 2/150 (1%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 297
++ IVG GL+G AM G VTV + A A E + L G+ RG++
Sbjct: 288 RVAIVGGGLMGAGVAMACLGGGLSVTVIERDAAAAQAAQERVA----GLVAAGVKRGKIS 343
Query: 298 ASEQFQCIK--GSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 471
Q + +TD A E V E+LD+K+ VF +L +V+ + I
Sbjct: 344 PDAQADMLARLATTDTYADASDADLAIEAVFEDLDVKRIVFADLAAVMRPDAILATNTSY 403
Query: 472 XXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
G+ + ++ + H +P + + L
Sbjct: 404 LDPQLVFAGIANPARCLGLHFFSPAHVMKL 433
>UniRef50_A1WHE6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Verminephrobacter eiseniae EF01-2|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Verminephrobacter eiseniae (strain
EF01-2)
Length = 319
Score = 41.1 bits (92), Expect = 0.037
Identities = 27/108 (25%), Positives = 50/108 (46%)
Frame = +1
Query: 127 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASE 306
++G+G++G + A G V VYD+ + + + + D + E +
Sbjct: 9 VLGAGVLGGQISWHSAFKGKSVVVYDISEEALARCRAAQAHYAAIYQTDAVGASEADVAG 68
Query: 307 QFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTI 450
Q + +TDL +AV A V E VPE +K V+Q + ++ +T+
Sbjct: 69 ARQRLTFATDLASAVASADLVIEAVPEIPQVKTSVYQQMAPLLPAHTL 116
>UniRef50_Q6D2L7 Cluster: Fatty acid oxidation complex subunit alpha
[Includes: Enoyl-CoA hydratase/3-hydroxybutyryl-CoA
epimerase (EC 4.2.1.17) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)]; n=16;
Gammaproteobacteria|Rep: Fatty acid oxidation complex
subunit alpha [Includes: Enoyl-CoA
hydratase/3-hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.1.2.3); 3-hydroxyacyl-CoA dehydrogenase (EC
1.1.1.35)] - Erwinia carotovora subsp. atroseptica
(Pectobacterium atrosepticum)
Length = 731
Score = 41.1 bits (92), Expect = 0.037
Identities = 38/149 (25%), Positives = 63/149 (42%), Gaps = 1/149 (0%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVG-YQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
++GI+G GL+G A + A+ G V + D+ + I A++ +QL T
Sbjct: 324 RVGILGGGLMGGGIASVTATRGQLPVRIKDINEQGINHALK-YNWQLLTKRVQSKRMKPT 382
Query: 295 KASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 474
+ I GSTD + A V E V E+L LK+++ ++ +TI
Sbjct: 383 ERQRLMTLISGSTDYR-GFEHADIVIEAVFEDLALKRQMITEIEDHAAPHTIFASNTSSL 441
Query: 475 XXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
EG + V+ H +P +PL
Sbjct: 442 PIHQIAEGARRPQLVVGLHYFSPVDKMPL 470
>UniRef50_Q8YB80 Cluster: 3-HYDROXYBUTYRYL-COA DEHYDROGENASE; n=32;
Proteobacteria|Rep: 3-HYDROXYBUTYRYL-COA DEHYDROGENASE -
Brucella melitensis
Length = 565
Score = 40.7 bits (91), Expect = 0.048
Identities = 33/141 (23%), Positives = 56/141 (39%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
I IVG+G++G A + A G ++D +++ + L L G + E A
Sbjct: 48 IAIVGAGVMGTGIAQIAAQAGLVTQIFDAREGAAAASLDRLASTLAKLAEKGKISAE-DA 106
Query: 301 SEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 480
I+ + ++ + V E + E LD K+ +F L++VV N I
Sbjct: 107 QTAVSRIEICSSIQ-ELADCDLVVEAIVEKLDAKQALFLELEAVVSGNCILATNTSSLSV 165
Query: 481 XXXXEGLKHKSQVIVSHPVNP 543
+H +V H NP
Sbjct: 166 TSIARVCRHPERVAGFHFFNP 186
>UniRef50_A3ZYI9 Cluster: Fatty oxidation complex, alpha subunit
FadB; n=1; Blastopirellula marina DSM 3645|Rep: Fatty
oxidation complex, alpha subunit FadB - Blastopirellula
marina DSM 3645
Length = 724
Score = 40.7 bits (91), Expect = 0.048
Identities = 27/116 (23%), Positives = 54/116 (46%)
Frame = +1
Query: 103 KFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLL 282
K K E + ++G+G++G A G T+ D A+ + + + + + D
Sbjct: 314 KTKIESVSVIGAGIMGAGIAAASIRRGILTTLSDANAEALRRGVAGVLEEA-AYDRDAGK 372
Query: 283 RGELKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTI 450
+ KA E + S ++ V + V E + ENL++K+K++ L+ + D+ I
Sbjct: 373 KTIAKAVEGAAMLNASIS-DSEVAASKLVIEAIVENLEVKRKIYARLEPQLADDAI 427
>UniRef50_Q9AF94 Cluster: 3-hydroxyacyl-CoA-dehydrogenase; n=1;
Acinetobacter sp. DF4|Rep:
3-hydroxyacyl-CoA-dehydrogenase - Acinetobacter sp. DF4
Length = 240
Score = 40.3 bits (90), Expect = 0.064
Identities = 31/119 (26%), Positives = 60/119 (50%), Gaps = 2/119 (1%)
Frame = +1
Query: 100 SKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGL 279
+K+++ K+G++G+G++G A A G V + DV + +A + Y L+ +
Sbjct: 123 TKWQATKVGVLGAGMMGAGIAYSTAIKGIPVVLKDV---SVENAEKGKAYSQKLLDK-RV 178
Query: 280 LRGELKASEQFQCIKGSTDLETA--VKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTI 450
+G + A ++ Q + T +A ++G + E V EN +LK KV Q + + N +
Sbjct: 179 SQGRMTAEKRDQVLSLITATASAQDLQGCDLIIEAVFENQELKAKVTQEAEQYLAPNGV 237
>UniRef50_Q1ATL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Rubrobacter xylanophilus DSM 9941|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 287
Score = 39.9 bits (89), Expect = 0.085
Identities = 30/142 (21%), Positives = 59/142 (41%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
+G++G+G +G + A GY+V D + + A ++ L + G L E +A
Sbjct: 5 VGVLGTGTMGAGIVQVAARAGYRVVACDASEEALGKARRYVRSGLESFARRGAL-SEEEA 63
Query: 301 SEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 480
++ +T +E + G+ V E + E + KK+ F LD+++ + +
Sbjct: 64 EAALGRVRWTTAME-ELAGSEAVIEAIVERVGPKKEAFAALDALLPPDALLLTNTSSISI 122
Query: 481 XXXXEGLKHKSQVIVSHPVNPP 546
+V +H PP
Sbjct: 123 TELASATGRPERVCGAHFFTPP 144
>UniRef50_A5WEP3 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=7; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Psychrobacter sp. PRwf-1
Length = 723
Score = 39.9 bits (89), Expect = 0.085
Identities = 36/154 (23%), Positives = 65/154 (42%), Gaps = 3/154 (1%)
Frame = +1
Query: 109 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG 288
K K+GI+G+G++G A + A G V + D +A E K L + + RG
Sbjct: 321 KVSKVGILGAGMMGAGIAYVSAKAGIDVVLLDT----SIEAAEKGKDYSSKLLDKAIARG 376
Query: 289 ELKASEQFQCIKGSTDLETA---VKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXX 459
++ Q + + TA ++ + E V E++D+K +N ++V+ + I
Sbjct: 377 R-STEQKKQALLDKINTTTAYDDLEDCDLIIEAVFEDIDIKAACTRNTEAVIAETAIYAS 435
Query: 460 XXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
+ K +Q I H +P +PL
Sbjct: 436 NTSTLPITELAKASKRPNQFIGLHFFSPVDKMPL 469
>UniRef50_A1SQH4 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=104; cellular organisms|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 736
Score = 39.9 bits (89), Expect = 0.085
Identities = 37/155 (23%), Positives = 66/155 (42%), Gaps = 3/155 (1%)
Frame = +1
Query: 106 FKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLR 285
+++ K+G++G+G++G A A G +V + DV ++ E K L + + +
Sbjct: 322 YRAVKVGVLGAGMMGAGIAYSCARSGMEVVLKDVA----VESAEKGKAYSEKLLDKAIAK 377
Query: 286 G---ELKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXX 456
G E K +E I + D + G V E V E+ LK++VF + VD + +
Sbjct: 378 GRSTEEKKAELLGRITATAD-AADLAGCDLVIEAVFEDPSLKQQVFAEIAPYVDQDALLC 436
Query: 457 XXXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
G+ + I H +P +PL
Sbjct: 437 SNTSTLPITELASGVDRPADFIGLHFFSPVDKMPL 471
>UniRef50_Q88X11 Cluster: NADH peroxidase; n=1; Lactobacillus
plantarum|Rep: NADH peroxidase - Lactobacillus plantarum
Length = 438
Score = 39.5 bits (88), Expect = 0.11
Identities = 29/83 (34%), Positives = 47/83 (56%), Gaps = 3/83 (3%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQL---HTLENDGLLR 285
+ + ++G G IG ++A LF G QVTV DV A+ + ++ Q+ ++EN GL
Sbjct: 137 KNVVVIGGGYIGMNFAALFKQTGKQVTVIDVNARPFSHNLDSEFTQILAAASVEN-GL-- 193
Query: 286 GELKASEQFQCIKGSTDLETAVK 354
+LK E+ + GST + TAV+
Sbjct: 194 -QLKMEERVTAVLGSTHV-TAVQ 214
>UniRef50_Q0SEV8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=34;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 298
Score = 39.5 bits (88), Expect = 0.11
Identities = 38/155 (24%), Positives = 68/155 (43%), Gaps = 4/155 (2%)
Frame = +1
Query: 109 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG 288
K +++G++G+G++G A + A V V++ + I L +L+ G+ G
Sbjct: 5 KIQRVGVIGAGIMGAGIAEVCARAHVDVLVFEQTRELAAAGRSRI---LRSLDR-GVSSG 60
Query: 289 ELKASEQFQC---IKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVV-DDNTIXX 456
++ E+ Q ++ ++DL + V E V E+ +K ++F LD VV D N +
Sbjct: 61 KITEREREQAAWRLRFTSDLGDFADRQLVV-EAVVEDEKVKSEIFTELDQVVTDPNAVLA 119
Query: 457 XXXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
K +VI H NP +PL
Sbjct: 120 SNTSSIPIMKLGIATKSPERVIGMHFFNPVPVLPL 154
>UniRef50_A0J682 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Shewanella woodyi ATCC 51908|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Shewanella woodyi ATCC 51908
Length = 696
Score = 39.5 bits (88), Expect = 0.11
Identities = 31/147 (21%), Positives = 62/147 (42%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
+G+VG+G +G A F G + + + + +++++ + G + E
Sbjct: 308 VGVVGAGNMGVGIARCFIDAGMDLIWIEQTEEALLRGMDNLRKGYQSKITKGHMT-EQDL 366
Query: 301 SEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 480
++ Q +KGST + + V E E+L++KK +F+ LD D+ I
Sbjct: 367 DDKMQLVKGSTVYDRLAPCDLVV-EAAFEDLEVKKIIFKALDQHCKDSAILATNTSYLDI 425
Query: 481 XXXXEGLKHKSQVIVSHPVNPPYYVPL 561
+ QV+ H +P + + L
Sbjct: 426 NSIAKVTSRPDQVVGLHFFSPAHVMKL 452
>UniRef50_Q5V581 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Haloarcula marismortui|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Haloarcula marismortui (Halobacterium
marismortui)
Length = 290
Score = 39.5 bits (88), Expect = 0.11
Identities = 31/142 (21%), Positives = 61/142 (42%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
+ ++G+G GR A G++V + A + D +++I+ + +L A
Sbjct: 3 VAVLGTGQRGRDVAQRCVRAGHEVRLQGTDASDVMDRVDEIRRAFNR---------DLSA 53
Query: 301 SEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 480
I G+T LE+AV G+ V + + ++V +++V+D TI
Sbjct: 54 G-----IDGTTGLESAVSGSDVVIDATNGGTESHREVVAETETMVEDETIIAVSDTSLSV 108
Query: 481 XXXXEGLKHKSQVIVSHPVNPP 546
GL+ + + + V+PP
Sbjct: 109 TAVATGLRSPDRAVGLNLVDPP 130
>UniRef50_Q6MHW5 Cluster: Glucose-inhibited division protein; n=1;
Bdellovibrio bacteriovorus|Rep: Glucose-inhibited
division protein - Bdellovibrio bacteriovorus
Length = 440
Score = 39.1 bits (87), Expect = 0.15
Identities = 23/74 (31%), Positives = 38/74 (51%)
Frame = +1
Query: 94 MASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLEND 273
M + +++KI +VG+GL G A+ A +GY V +Y++ K +T A + K+ N
Sbjct: 1 MTNITQNQKITVVGAGLAGSECALQLADMGYSVVLYEMRDKTMTPAHKTHKFAELVCSNS 60
Query: 274 GLLRGELKASEQFQ 315
GE A Q +
Sbjct: 61 FGSLGEHSAPGQLK 74
>UniRef50_A1IDF2 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerase family protein precursor; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerase family protein precursor -
Candidatus Desulfococcus oleovorans Hxd3
Length = 801
Score = 39.1 bits (87), Expect = 0.15
Identities = 37/161 (22%), Positives = 65/161 (40%), Gaps = 10/161 (6%)
Frame = +1
Query: 109 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIED--------IKYQLHTL 264
K +K ++GSG++G A L AS G + + D+V +TD + +K+ T+
Sbjct: 4 KIKKAAVIGSGVMGGGIAALLASAGVETLLLDIVPFDLTDEQKKDPAARNRIVKFGYDTI 63
Query: 265 ENDGLLRGELKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDN 444
+ I D + ++ E V ENL +K+++F+ ++ V
Sbjct: 64 MMSRPAALMHSSDAALISIGNLEDDFDKLADCDWIVEVVVENLKIKQQLFKRIEPVRKKG 123
Query: 445 TIXXXXXXXXXXXXXXEGLK--HKSQVIVSHPVNPPYYVPL 561
+I EGL K + +H NP Y+ L
Sbjct: 124 SIISSNTSGIPLKAMSEGLSSDFKQHFLGTHFFNPVRYMHL 164
>UniRef50_P35484 Cluster: Dihydrolipoyl dehydrogenase; n=3;
Acholeplasmataceae|Rep: Dihydrolipoyl dehydrogenase -
Acholeplasma laidlawii
Length = 336
Score = 39.1 bits (87), Expect = 0.15
Identities = 28/102 (27%), Positives = 51/102 (50%), Gaps = 4/102 (3%)
Frame = +1
Query: 76 VASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKY-Q 252
V S ++ K + I IVG G+IG +A +F S G +VT+ +++ + +DI+
Sbjct: 161 VTSRELLNVKNYPKSIVIVGGGVIGVEFATVFNSFGSKVTIIEMMDGILPTMDDDIRVAY 220
Query: 253 LHTLENDG---LLRGELKASEQFQCIKGSTDLETAVKGAIFV 369
TL+ DG L + E+K + + ET ++G + +
Sbjct: 221 AKTLKRDGIEILTKAEVKKVDDHKVTYSLDGKETTIEGDLIL 262
>UniRef50_Q8FX64 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=10; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Brucella suis
Length = 509
Score = 38.7 bits (86), Expect = 0.20
Identities = 33/141 (23%), Positives = 55/141 (39%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
I IVG+G++G A + A G ++D + + + L L G + E A
Sbjct: 8 IAIVGAGVMGTGIAQIAAQAGLVTQIFDAREGAAAASRDRLASTLAKLAEKGKISAE-DA 66
Query: 301 SEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 480
I+ + ++ + V E + E LD K+ +F L++VV N I
Sbjct: 67 QTAVSRIEICSSIQ-ELADCDLVVEAIVEKLDAKQALFLELEAVVSGNCILATNTSSLSV 125
Query: 481 XXXXEGLKHKSQVIVSHPVNP 543
+H +V H NP
Sbjct: 126 TSIARVCRHPERVAGFHFFNP 146
>UniRef50_Q39TJ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like; n=1;
Geobacter metallireducens GS-15|Rep: 3-hydroxyacyl-CoA
dehydrogenase-like - Geobacter metallireducens (strain
GS-15 / ATCC 53774 / DSM 7210)
Length = 290
Score = 38.7 bits (86), Expect = 0.20
Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 2/114 (1%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
+K+ I+G+G++G A+ A GY V + +V +E I+ L G L +
Sbjct: 5 KKVAILGAGMMGSDIALSCALAGYDVLLKEVSLDLAAAGVERIRGSLAKWSEKGRL--AV 62
Query: 295 KASEQFQCIKGSTDLE--TAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTI 450
A +Q + T ++ + V E + E+LD+K + F+ L+ V + I
Sbjct: 63 DAEQQKSAVARITPVDNFSGFGDVDLVIEAIFEDLDVKSQNFRQLEEVCKPSCI 116
>UniRef50_Q8KUG1 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=8;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Actinosynnema pretiosum subsp. auranticum
Length = 341
Score = 38.7 bits (86), Expect = 0.20
Identities = 33/144 (22%), Positives = 58/144 (40%)
Frame = +1
Query: 127 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASE 306
++G+G++G L S G V + D A ++ A D++ L T + G+ G L
Sbjct: 62 VLGAGVMGCGITALALSRGLPVLLVDPDADRLDAARADVRAHLRTAQLLGVAAGPLGE-- 119
Query: 307 QFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXX 486
+ +TD + + V E V E+ + K K + + V T
Sbjct: 120 ----LTTATDTG-GPREVVAVVEAVTEDAETKAKALTGVCATVPPGTPLVSNTSSIPMGE 174
Query: 487 XXEGLKHKSQVIVSHPVNPPYYVP 558
L ++ +H +NPPY +P
Sbjct: 175 LAPALPRPGDLVGAHFMNPPYLIP 198
>UniRef50_Q0C0V2 Cluster: Oxidoreductase, FAD-binding; n=2;
Proteobacteria|Rep: Oxidoreductase, FAD-binding -
Hyphomonas neptunium (strain ATCC 15444)
Length = 377
Score = 38.7 bits (86), Expect = 0.20
Identities = 21/59 (35%), Positives = 33/59 (55%), Gaps = 1/59 (1%)
Frame = +1
Query: 61 LSCGTVASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVY-DVVAKQITDAI 234
LS GT +MA + + + I+G G++G + A++ A G+ VTVY DV+ T I
Sbjct: 87 LSWGTCQRAAVMAGETGRQDVAILGGGVMGLTSALILARRGHDVTVYADVMHPNTTSNI 145
>UniRef50_A4SW27 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7;
Burkholderiales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 313
Score = 38.7 bits (86), Expect = 0.20
Identities = 19/59 (32%), Positives = 32/59 (54%)
Frame = +2
Query: 542 HLITYPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRIQYAILDEVW 718
HL+ P VE+V T P V +M G PV++ +++ F+ NR+Q+A+ E +
Sbjct: 143 HLV--PCVEVVYGEKTSPMVGDSLSRLMTACGMVPVTVKKDLPGFLANRLQHALSREAF 199
Score = 37.9 bits (84), Expect = 0.34
Identities = 37/147 (25%), Positives = 61/147 (41%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 297
K+ IVG G +G A + A G V V + ++ + D Y ++T+ + G +
Sbjct: 9 KVVIVGGGTMGADVAAVCARGGCAVQVVEPTTERRA-LLPD--YFVNTMTDLGY-----E 60
Query: 298 ASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 477
+ GS + E V ECVPE LD+K+++F L+ +
Sbjct: 61 HRIHLLTVAGSLE-EVDWADVDLVIECVPERLDIKQELFAKLEKYAKPEAVLASNSTSFP 119
Query: 478 XXXXXEGLKHKSQVIVSHPVNPPYYVP 558
GLK +++I H P + VP
Sbjct: 120 ISEIASGLKTAARMIGLHFFMPAHLVP 146
>UniRef50_Q0CYI1 Cluster: Predicted protein; n=1; Aspergillus
terreus NIH2624|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 192
Score = 38.7 bits (86), Expect = 0.20
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
Frame = +1
Query: 367 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXXEG--LKHKSQVIVSHPVN 540
V ECVPE+L LK+ + + LD TI +G LK K +++ HP
Sbjct: 9 VVECVPESLSLKRSLLRKLDKATRPETIIASNSSSYNIPEIAKGIALKGKDRIVNMHPFL 68
Query: 541 PP 546
PP
Sbjct: 69 PP 70
>UniRef50_Q45223 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=92;
cellular organisms|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Bradyrhizobium japonicum
Length = 293
Score = 38.7 bits (86), Expect = 0.20
Identities = 26/112 (23%), Positives = 54/112 (48%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
+K+G++G+G +G A + A G+ V + DV A ++ + I L + ++ E
Sbjct: 6 KKVGVIGAGQMGNGIAHVAALAGFDVVLNDVSADRLKSGMATINGNLARQVSKKVVTEEA 65
Query: 295 KASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTI 450
K ++ I + L+ + ++ V E ++K+K+F L +V+ I
Sbjct: 66 K-TKALSRIVAAEKLDDLADCDLVIETAV-EKEEVKRKIFHELCAVLKPEAI 115
>UniRef50_Q1IUZ3 Cluster: UDP-glucose/GDP-mannose dehydrogenase;
n=1; Acidobacteria bacterium Ellin345|Rep:
UDP-glucose/GDP-mannose dehydrogenase - Acidobacteria
bacterium (strain Ellin345)
Length = 422
Score = 38.3 bits (85), Expect = 0.26
Identities = 24/94 (25%), Positives = 46/94 (48%), Gaps = 2/94 (2%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
+G+ GSG +G + A +G VT YD + D+ + + H ++R ++A
Sbjct: 3 VGVYGSGYLGTVVSACLADLGMPVTCYDADTTLVMDSAQG-TLRFHEKNLKEIVRRNVRA 61
Query: 301 SEQFQCIKGSTDLETAVK--GAIFVQECVPENLD 396
+ +T+LE+ + GAIF+ E P+ ++
Sbjct: 62 DR----LMYTTELESVARRAGAIFIAEDTPDEIE 91
>UniRef50_A3D4X7 Cluster: FAD dependent oxidoreductase; n=3;
Shewanella baltica|Rep: FAD dependent oxidoreductase -
Shewanella baltica OS155
Length = 578
Score = 38.3 bits (85), Expect = 0.26
Identities = 18/45 (40%), Positives = 29/45 (64%)
Frame = +1
Query: 79 ASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVA 213
A+ +++ S KS+ + I G G+ G + A FA +GYQV V++V A
Sbjct: 13 ATELLIKSSTKSKSVAIFGGGIAGLTAAHEFAKLGYQVKVFEVNA 57
>UniRef50_O17761 Cluster: Putative uncharacterized protein ech-8;
n=4; Caenorhabditis|Rep: Putative uncharacterized
protein ech-8 - Caenorhabditis elegans
Length = 437
Score = 38.3 bits (85), Expect = 0.26
Identities = 33/146 (22%), Positives = 65/146 (44%), Gaps = 3/146 (2%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLH-TLENDGLLR-- 285
+ + ++G G +GR A+ F G++ + +V K A E K +L T + + R
Sbjct: 40 KSVAVIGGGTMGRGIAIAFCLSGFETYLVEVNNK----AAEFCKNELEITYKREKAFRRL 95
Query: 286 GELKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXX 465
+ K + + ++ +TD + + + E V E++ LKK++F LD + + I
Sbjct: 96 NDSKVEKLRKNLQITTDFQ-KLNNCDLIVEAVFEDMKLKKELFTKLDKICKPSCIFGTNT 154
Query: 466 XXXXXXXXXEGLKHKSQVIVSHPVNP 543
L+ ++V+ H NP
Sbjct: 155 SSLDLNEMSSVLRDPTKVVGIHFFNP 180
>UniRef50_UPI000018F68E Cluster: hypothetical protein Rm378p142;
n=1; Rhodothermus phage RM378|Rep: hypothetical protein
Rm378p142 - Bacteriophage RM 378
Length = 282
Score = 37.9 bits (84), Expect = 0.34
Identities = 17/68 (25%), Positives = 35/68 (51%)
Frame = +1
Query: 235 EDIKYQLHTLENDGLLRGELKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVF 414
EDIK + ++ DG L E++ + D++ +KGA+ +E V E +DL +
Sbjct: 130 EDIKIDVEDVDEDGELEAEIELKDADLSDDEELDIDVDIKGAVESEEHVREEMDLLHTLL 189
Query: 415 QNLDSVVD 438
+ ++ ++
Sbjct: 190 ERVEEAIE 197
>UniRef50_Q5NW50 Cluster: DitN-like 3-hydroxyacyl-CoA
dehydrogenase,possibly related to diterpenoid
metabolism; n=6; Proteobacteria|Rep: DitN-like
3-hydroxyacyl-CoA dehydrogenase,possibly related to
diterpenoid metabolism - Azoarcus sp. (strain EbN1)
(Aromatoleum aromaticum (strain EbN1))
Length = 299
Score = 37.9 bits (84), Expect = 0.34
Identities = 32/152 (21%), Positives = 61/152 (40%), Gaps = 3/152 (1%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
EKI +VG+GL+G A A GY++ + D + A+ Q+++L G+ G+L
Sbjct: 5 EKIIVVGAGLMGTGIAYSCAISGYRILLVDANPSALDKAVG----QINSLVAAGVKLGKL 60
Query: 295 ---KASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXX 465
+ ++ + +L+ A + E E +D+K + D ++ I
Sbjct: 61 VEAAGKAALERLEAAIELDGRASDAALLIETATEKIDIKLAIIGKADELLPPEAIIASNT 120
Query: 466 XXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
+ +Q H NP + + L
Sbjct: 121 SALSISELAAATRRPTQFAGMHFFNPVHKMKL 152
>UniRef50_A6P2M7 Cluster: Putative uncharacterized protein; n=2;
Bacteria|Rep: Putative uncharacterized protein -
Bacteroides capillosus ATCC 29799
Length = 321
Score = 37.9 bits (84), Expect = 0.34
Identities = 17/66 (25%), Positives = 30/66 (45%)
Frame = +1
Query: 43 F*FTRGLSCGTVASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQI 222
F T L C T+ + + + + KI +G G++G+S GY +T+Y +
Sbjct: 12 FSLTAPLPCFTIKAAGMRKERIEMNKIAFIGVGIMGKSMVRNLMKAGYSLTIYSRTKAKC 71
Query: 223 TDAIED 240
D I +
Sbjct: 72 EDVIAE 77
>UniRef50_A4WWF6 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=5; Rhodobacteraceae|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Rhodobacter sphaeroides ATCC 17025
Length = 673
Score = 37.9 bits (84), Expect = 0.34
Identities = 31/148 (20%), Positives = 61/148 (41%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 297
+IG++G G +G A A+ G + T+ + + I+ ++ G L
Sbjct: 292 RIGVIGGGTMGSGIAAAIAAAGLEATLAETGPDALEAGIKRVRAIFEAQVTRG-LTDRAG 350
Query: 298 ASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 477
A+++ + G+ L + V E V E+L +K++VF++L + + I
Sbjct: 351 AADRLARVSGTVGL-GPLADCDLVIEAVFEDLAVKRRVFEDLTRLCRPDAILATNTSYLD 409
Query: 478 XXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
GL + + I H +P + L
Sbjct: 410 PERIVAGLPNPDRFIALHFFSPAQVMKL 437
>UniRef50_Q8U0F8 Cluster: NDP-sugar dehydrogenase; n=4;
Thermococcaceae|Rep: NDP-sugar dehydrogenase -
Pyrococcus furiosus
Length = 434
Score = 37.9 bits (84), Expect = 0.34
Identities = 31/106 (29%), Positives = 52/106 (49%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 297
KI ++G G IG A++FA GY+V +D V K + D I K H +E + +L
Sbjct: 18 KIAVIGLGYIGLPTAIMFAEAGYEVIGFD-VKKDVVDRINSGK--AHIVEPG--IEEKLN 72
Query: 298 ASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVV 435
+ + +K +T +E ++GA CV L+ K L++ +
Sbjct: 73 KVVKEERLKATTKVE-KLRGANAFIICVQTPLEGNKPNLIYLENAI 117
>UniRef50_P14218 Cluster: Dihydrolipoyl dehydrogenase; n=65;
cellular organisms|Rep: Dihydrolipoyl dehydrogenase -
Pseudomonas fluorescens
Length = 478
Score = 37.9 bits (84), Expect = 0.34
Identities = 23/69 (33%), Positives = 38/69 (55%), Gaps = 1/69 (1%)
Frame = +1
Query: 76 VASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDI-KYQ 252
V ST + + +K+G++G+G+IG ++A +G +VTV + + K + A E I K
Sbjct: 169 VDSTGALEFQAVPKKLGVIGAGVIGLELGSVWARLGAEVTVLEALDKFLPAADEQIAKEA 228
Query: 253 LHTLENDGL 279
L L GL
Sbjct: 229 LKVLTKQGL 237
>UniRef50_Q8G3X6 Cluster: Possible class I pyridine
nucleotide-disulfideoxidoreductase; n=2; Bifidobacterium
longum|Rep: Possible class I pyridine
nucleotide-disulfideoxidoreductase - Bifidobacterium
longum
Length = 544
Score = 37.5 bits (83), Expect = 0.45
Identities = 30/100 (30%), Positives = 43/100 (43%), Gaps = 4/100 (4%)
Frame = +1
Query: 70 GTVASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVY----DVVAKQITDAIE 237
G ST +M +++ I+GSG IG +A +FA G VTV + + ++ D
Sbjct: 173 GVYTSTGLMDLDDMPQRLVIIGSGFIGLEFASMFADFGTAVTVLQHNAEFLPREDADVAA 232
Query: 238 DIKYQLHTLENDGLLRGELKASEQFQCIKGSTDLETAVKG 357
I+ QL L + KA G L AVKG
Sbjct: 233 AIRAQLEAQGVKFLFNADTKAIA--PAADGGVRLSVAVKG 270
>UniRef50_Q8CXB6 Cluster: UDP-glucose:GDP-mannose dehydrogenase;
n=2; Bacillaceae|Rep: UDP-glucose:GDP-mannose
dehydrogenase - Oceanobacillus iheyensis
Length = 440
Score = 37.5 bits (83), Expect = 0.45
Identities = 15/40 (37%), Positives = 25/40 (62%)
Frame = +1
Query: 106 FKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQIT 225
+ + K+G++G G +G A+LF GYQVT D+ +I+
Sbjct: 12 YVNSKVGVIGMGYVGLPLALLFLKKGYQVTGIDINQSKIS 51
>UniRef50_Q89SH2 Cluster: Blr2428 protein; n=7; Rhizobiales|Rep:
Blr2428 protein - Bradyrhizobium japonicum
Length = 715
Score = 37.5 bits (83), Expect = 0.45
Identities = 33/141 (23%), Positives = 61/141 (43%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
+ ++G+G +G A A G +V++ D+ A+ I A++ +L+ ++R +
Sbjct: 343 VHVIGAGAMGGDIAAWCAGQGLRVSLADMKAEPIAGAVKRAA-ELY----GKIIRKPTEV 397
Query: 301 SEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 480
+ + D E V+ A V E VPE L+LK+KV+ L+ + I
Sbjct: 398 RDALDRLIPDMDGE-GVRNADLVIEAVPEKLELKQKVYAGLEPKMKPGAILATNTSSIPL 456
Query: 481 XXXXEGLKHKSQVIVSHPVNP 543
L +++ H NP
Sbjct: 457 QDLRTTLARPDRLVGLHFFNP 477
>UniRef50_Q88YA7 Cluster: Bifunctional protein: amino acid
aminotransferase; 2-hydroxyacid dehydrogenase; n=2;
Lactobacillus|Rep: Bifunctional protein: amino acid
aminotransferase; 2-hydroxyacid dehydrogenase -
Lactobacillus plantarum
Length = 543
Score = 37.5 bits (83), Expect = 0.45
Identities = 21/60 (35%), Positives = 34/60 (56%)
Frame = +1
Query: 91 IMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLEN 270
+ A + +S +GI+G+G IG + A LF +G +V YDVV +ED+ + T E+
Sbjct: 352 LQAREIRSLTVGIIGAGRIGGTAARLFHGLGAKVIAYDVVRH---PELEDVLTYVDTKED 408
>UniRef50_Q0SUA0 Cluster: Pyridine nucleotide-disulphide
oxidoreductase; n=9; Bacteria|Rep: Pyridine
nucleotide-disulphide oxidoreductase - Clostridium
perfringens (strain SM101 / Type A)
Length = 457
Score = 37.5 bits (83), Expect = 0.45
Identities = 26/80 (32%), Positives = 42/80 (52%), Gaps = 4/80 (5%)
Frame = +1
Query: 82 STVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYD----VVAKQITDAIEDIKY 249
ST IM K + + IVG G IG +A ++AS G +VTV + + ++ D + IK
Sbjct: 160 STTIMELKELPKHLVIVGGGYIGLEFASIYASFGSKVTVIEAFDRIAGREDEDISKSIKE 219
Query: 250 QLHTLENDGLLRGELKASEQ 309
L + LL ++K+ E+
Sbjct: 220 ILEKKGIEFLLGSKVKSFEE 239
>UniRef50_A4BGI3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Reinekea sp. MED297|Rep: 3-hydroxyacyl-CoA dehydrogenase
- Reinekea sp. MED297
Length = 705
Score = 37.5 bits (83), Expect = 0.45
Identities = 36/113 (31%), Positives = 49/113 (43%), Gaps = 2/113 (1%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 297
+IG+VG+G++G A AS G V + D + E K L RG L
Sbjct: 315 RIGVVGAGMMGAGIAWACASKGLPVVLVDTEQSR----AEQGKGYSERLVAKRFERGRLS 370
Query: 298 ASEQFQCIKGSTDLETAVKGA--IFVQECVPENLDLKKKVFQNLDSVVDDNTI 450
A E + T E+ + A V E V E+ LK V+Q + SVV TI
Sbjct: 371 AEEGTALLNRITPTESMSELAECDLVIEAVFEDRALKADVYQLIQSVVSPETI 423
>UniRef50_O34324 Cluster: Dihydrolipoyl dehydrogenase; n=13;
Bacillus|Rep: Dihydrolipoyl dehydrogenase - Bacillus
subtilis
Length = 458
Score = 37.5 bits (83), Expect = 0.45
Identities = 22/52 (42%), Positives = 30/52 (57%), Gaps = 1/52 (1%)
Frame = +1
Query: 127 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDI-KYQLHTLENDGL 279
IVG G+IG +A LFA +G QVT+ + + I EDI + LE DG+
Sbjct: 175 IVGGGVIGCEYAGLFARLGSQVTIIETADRLIPAEDEDIARLFQEKLEEDGV 226
>UniRef50_P38169 Cluster: Kynurenine 3-monooxygenase; n=4;
Saccharomycetales|Rep: Kynurenine 3-monooxygenase -
Saccharomyces cerevisiae (Baker's yeast)
Length = 460
Score = 37.5 bits (83), Expect = 0.45
Identities = 15/31 (48%), Positives = 22/31 (70%)
Frame = +1
Query: 112 SEKIGIVGSGLIGRSWAMLFASVGYQVTVYD 204
SE + I+G+GL+G A+ F+ GY VT+YD
Sbjct: 2 SESVAIIGAGLVGCLAALAFSKEGYNVTLYD 32
>UniRef50_Q8RC01 Cluster: UDP-N-acetyl-D-mannosaminuronate
dehydrogenase; n=18; Bacteria|Rep:
UDP-N-acetyl-D-mannosaminuronate dehydrogenase -
Thermoanaerobacter tengcongensis
Length = 445
Score = 37.1 bits (82), Expect = 0.60
Identities = 30/107 (28%), Positives = 49/107 (45%), Gaps = 2/107 (1%)
Frame = +1
Query: 94 MASKFKSEK--IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLE 267
+ K +S+K IG++G G +G A+ A GY+V +D+ ++ I Y
Sbjct: 14 LLDKIESKKAVIGVIGLGYVGLPLAVEKAKAGYKVIGFDIQKHKVEKVNNGINY------ 67
Query: 268 NDGLLRGELKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKK 408
+L G+LK + +K + D +K V CVP LD K+
Sbjct: 68 IGDILDGDLKEVVEQGRLKATNDY-AFLKDVDAVAICVPTPLDKNKQ 113
>UniRef50_Q82W31 Cluster: Phosphoribosylaminoimidazole carboxylase,
ATPase subunit; ATP-grasp domain; n=2;
Proteobacteria|Rep: Phosphoribosylaminoimidazole
carboxylase, ATPase subunit; ATP-grasp domain -
Nitrosomonas europaea
Length = 376
Score = 37.1 bits (82), Expect = 0.60
Identities = 18/53 (33%), Positives = 29/53 (54%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGL 279
+G++G G +GR +AM +GY+VTV D A+ +I + Q L + L
Sbjct: 9 LGLLGGGQLGRMFAMAAQQMGYRVTVLDPAAESPAGSIAERHLQADYLNDQAL 61
>UniRef50_Q67L77 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Symbiobacterium thermophilum
Length = 296
Score = 37.1 bits (82), Expect = 0.60
Identities = 30/104 (28%), Positives = 48/104 (46%), Gaps = 1/104 (0%)
Frame = +1
Query: 124 GIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQL-HTLENDGLLRGELKA 300
GIVG+G GR A L A+ G +V + +++ A + L H +E L + E +A
Sbjct: 7 GIVGTGPSGRGIAQLVATQGLEVIMVGRSEEELEQARRQLDLALQHEIEKWALTQSEKRA 66
Query: 301 SEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSV 432
I +TD+ K + V E + K++F+ LD V
Sbjct: 67 I--LARISMTTDINELAKADFVIATLVVEIAE-DKEIFRTLDQV 107
>UniRef50_Q5LVD0 Cluster: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase;
n=6; Rhodobacterales|Rep: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase -
Silicibacter pomeroyi
Length = 698
Score = 37.1 bits (82), Expect = 0.60
Identities = 31/107 (28%), Positives = 51/107 (47%), Gaps = 3/107 (2%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
IG++G G +G A G VT+ ++ +A E K ++ + L RG+L A
Sbjct: 292 IGVIGGGTMGAGIATAALLSGLSVTMLEMT----PEAAEAAKGRIEGNLSGALKRGKLTA 347
Query: 301 SEQFQCIKGSTDLE---TAVKGAIFVQECVPENLDLKKKVFQNLDSV 432
+ + L A+ A V E V E++++KK+VF LD+V
Sbjct: 348 QQFDNLTTKALTLAIDYDALADADLVIEAVFEDMEVKKQVFTKLDAV 394
>UniRef50_Q4A6P9 Cluster: Putative mercuric reductase; n=1;
Mycoplasma synoviae 53|Rep: Putative mercuric reductase
- Mycoplasma synoviae (strain 53)
Length = 459
Score = 37.1 bits (82), Expect = 0.60
Identities = 25/81 (30%), Positives = 41/81 (50%), Gaps = 1/81 (1%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQI-TDAIEDIKYQLHTLENDGLLRGE 291
+K+ +VG+G IG +A FA+ G QVTV + + ED K+ L TL+ G+
Sbjct: 177 KKLLVVGAGFIGLEFASYFANFGTQVTVAQYNNDFMPNEDKEDSKFILDTLKKQGIKFEF 236
Query: 292 LKASEQFQCIKGSTDLETAVK 354
E+F+ +K + + K
Sbjct: 237 NTTCEKFKDLKSQVQVSLSNK 257
>UniRef50_Q1FP37 Cluster: NADH:flavin oxidoreductase/NADH
oxidase:FAD-dependent pyridine nucleotide-disulphide
oxidoreductase:Acetoacetate decarboxylase; n=1;
Clostridium phytofermentans ISDg|Rep: NADH:flavin
oxidoreductase/NADH oxidase:FAD-dependent pyridine
nucleotide-disulphide oxidoreductase:Acetoacetate
decarboxylase - Clostridium phytofermentans ISDg
Length = 937
Score = 37.1 bits (82), Expect = 0.60
Identities = 19/53 (35%), Positives = 28/53 (52%)
Frame = +1
Query: 73 TVASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDA 231
TV S + S K EK+ ++G+GL G A G QVT+ D++ K +A
Sbjct: 503 TVESVLSGKSALKGEKVAVIGAGLTGLETAEYLFEEGNQVTIIDMLDKPAPNA 555
>UniRef50_A4XMY3 Cluster: Prephenate dehydrogenase; n=1;
Caldicellulosiruptor saccharolyticus DSM 8903|Rep:
Prephenate dehydrogenase - Caldicellulosiruptor
saccharolyticus (strain ATCC 43494 / DSM 8903)
Length = 290
Score = 37.1 bits (82), Expect = 0.60
Identities = 20/53 (37%), Positives = 31/53 (58%), Gaps = 2/53 (3%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIED--IKYQLHTLEN 270
KI +VG GLIG S A F G++V +D+ + AIE+ +K ++ LE+
Sbjct: 15 KILVVGLGLIGGSLAKAFHKCGFEVHAHDINQNSVEKAIEEGIVKEKIEDLED 67
>UniRef50_Q9HJM0 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase
related protein; n=3; Thermoplasmatales|Rep:
Beta-hydroxybutyryl-CoA dehydrogenase related protein -
Thermoplasma acidophilum
Length = 314
Score = 37.1 bits (82), Expect = 0.60
Identities = 44/176 (25%), Positives = 72/176 (40%), Gaps = 29/176 (16%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDV---VAKQITDAIEDIKYQLHTLENDGLLRGE 291
+G++G+G +G + A LFA G+ V + D +A+ IE I + + ND E
Sbjct: 6 VGVIGAGTMGSAIAELFAFNGFNVVMKDQNMDLARSGYSGIEKILNDMKRI-NDEKPEKE 64
Query: 292 LKASEQFQCIKGSTDLETAVKGAIFVQ--------------------------ECVPENL 393
+ E + IK S D + A++ I VQ E EN
Sbjct: 65 IARIENYG-IKLSDDQKNAIRKKIGVQVDVNAMLKRISLTDKYSDLSSCDLVIEAAFENQ 123
Query: 394 DLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
D+K ++F ++ S + ++ I LK ++ H NPPY +PL
Sbjct: 124 DVKNRIFSDI-SDLSEHAIIASNTSSLSITEMSSRLKRPENALILHFFNPPYLLPL 178
>UniRef50_Q9X0U4 Cluster: Glutamate synthase, beta subunit; n=5;
Bacteria|Rep: Glutamate synthase, beta subunit -
Thermotoga maritima
Length = 618
Score = 36.7 bits (81), Expect = 0.79
Identities = 15/36 (41%), Positives = 24/36 (66%)
Frame = +1
Query: 109 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAK 216
K + +GI+GSG G + A A++GY VT+Y+ +K
Sbjct: 295 KGKSVGIIGSGPAGLAAAYFLATMGYDVTIYESESK 330
>UniRef50_Q8CX86 Cluster: UDP-glucose:GDP-mannose dehydrogenase;
n=16; Bacteria|Rep: UDP-glucose:GDP-mannose
dehydrogenase - Oceanobacillus iheyensis
Length = 448
Score = 36.7 bits (81), Expect = 0.79
Identities = 27/100 (27%), Positives = 51/100 (51%)
Frame = +1
Query: 109 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG 288
KS +G+VG G +G A+ A GY+V +DV ++I + I Y + + ++ L+
Sbjct: 23 KSATLGVVGLGYVGLPLAVEKAKAGYKVIGFDVQLEKIEKLAQGINY-IGDVNDEELI-- 79
Query: 289 ELKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKK 408
++ ++F +T+ + + V CVP LD+ K+
Sbjct: 80 QVINKDKFY----ATNDYSLINNVDVVVICVPTPLDIHKQ 115
>UniRef50_Q7WIS8 Cluster: Putative enoyl-CoA isomerase; n=2;
Bordetella|Rep: Putative enoyl-CoA isomerase -
Bordetella bronchiseptica (Alcaligenes bronchisepticus)
Length = 694
Score = 36.7 bits (81), Expect = 0.79
Identities = 32/149 (21%), Positives = 55/149 (36%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
E++ +VG+G +G + A G V +DV A ++ + L L
Sbjct: 288 EQVAVVGAGTMGTGIVICLADAGLPVIWHDVDADRLAQGRAQVCQHFERLAARKRLTS-- 345
Query: 295 KASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 474
+ +EQ +T + A E V E++ +K VF+ LD V+ I
Sbjct: 346 RQAEQRVAAVATTGEMAGIAQADLAIEAVFEDMAVKCAVFRELDRVLKPGAILGTNTSTL 405
Query: 475 XXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
+ V+ H +P +PL
Sbjct: 406 DVDRIAHSTRRPQDVVGLHFFSPAPVMPL 434
>UniRef50_Q8GP50 Cluster: Eps11H; n=13; Lactobacillales|Rep: Eps11H
- Streptococcus thermophilus
Length = 416
Score = 36.7 bits (81), Expect = 0.79
Identities = 30/104 (28%), Positives = 50/104 (48%)
Frame = +1
Query: 103 KFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLL 282
+FK KI + G+G +G S A L S ++VT D+ I + +E I + ++++ +
Sbjct: 3 EFKDLKIAVAGTGYVGLSIATLL-SQHHKVTAVDI----IPEKVELINNKKSPIQDEYI- 56
Query: 283 RGELKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVF 414
E +E+ + + D + A A FV P N D KK F
Sbjct: 57 --EKYLAEKELDLTATLDAKEAYSDADFVVIAAPTNYDSKKNFF 98
>UniRef50_A0LI43 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Syntrophobacter fumaroxidans MPOB|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Length = 681
Score = 36.7 bits (81), Expect = 0.79
Identities = 35/149 (23%), Positives = 59/149 (39%), Gaps = 1/149 (0%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFAS-VGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
K+GIVG+GL+ A LF + V + D+ + + + L G L E
Sbjct: 318 KVGIVGAGLMASQLAQLFIERLEVPVVMKDISPEALEKGCGQVVEGFRRLGEKGKLT-EG 376
Query: 295 KASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 474
KA + G+ D FV E V E + +KK+V L+ ++ + +
Sbjct: 377 KARHLAGLVSGTLDFRD-FSDCDFVIEAVFEEMAVKKQVLGELEPLLRPDAVIATNTSSL 435
Query: 475 XXXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
L+ +++ H NP +PL
Sbjct: 436 SVTEMASVLRVPGRMLGFHFFNPVAVLPL 464
>UniRef50_Q9N5G1 Cluster: Dehydrogenases, short chain protein 15;
n=4; Caenorhabditis|Rep: Dehydrogenases, short chain
protein 15 - Caenorhabditis elegans
Length = 278
Score = 36.7 bits (81), Expect = 0.79
Identities = 25/76 (32%), Positives = 43/76 (56%), Gaps = 3/76 (3%)
Frame = +1
Query: 112 SEKIGIV--GSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLR 285
S+K+ I+ S IGRS A+L A G +VTV +++I + + +I + +N ++
Sbjct: 5 SDKVAIITGSSSGIGRSTAVLLAQEGAKVTVTGRSSEKIQETVNEIHKNGGSSDNINIVL 64
Query: 286 GELKASE-QFQCIKGS 330
G+L SE Q + IK +
Sbjct: 65 GDLNESECQDELIKST 80
>UniRef50_Q9YBW6 Cluster: 3-hydroxyacyl-CoA
dehydrogenase/3-hydroxybutyryl-CoA dehydratase; n=19;
cellular organisms|Rep: 3-hydroxyacyl-CoA
dehydrogenase/3-hydroxybutyryl-CoA dehydratase -
Aeropyrum pernix
Length = 669
Score = 36.7 bits (81), Expect = 0.79
Identities = 15/48 (31%), Positives = 29/48 (60%)
Frame = +2
Query: 548 ITYPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDXFVLNRI 691
+ PLVE+V T E T ++ +++G+Q V + +++ F++NRI
Sbjct: 157 VLMPLVEVVKGEKTSEETVAATVDLAKKMGKQTVVVKKDVPGFIVNRI 204
>UniRef50_Q834J0 Cluster: Dihydrolipoyl dehydrogenase; n=3;
Lactobacillales|Rep: Dihydrolipoyl dehydrogenase -
Enterococcus faecalis (Streptococcus faecalis)
Length = 469
Score = 36.3 bits (80), Expect = 1.0
Identities = 19/56 (33%), Positives = 30/56 (53%), Gaps = 1/56 (1%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQL-HTLENDGL 279
E I I+G G+IG WA L S+G VT+ + + + + + I +L LE G+
Sbjct: 183 ESIAIIGGGVIGVEWASLLNSLGVNVTIIEFLDRLLINESATISKELKKRLEQRGI 238
>UniRef50_Q28N18 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=23; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding - Jannaschia
sp. (strain CCS1)
Length = 733
Score = 36.3 bits (80), Expect = 1.0
Identities = 30/115 (26%), Positives = 57/115 (49%), Gaps = 3/115 (2%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG-- 288
+K+GI+G+G++G A + A G +V + D D+ + K L + G+ RG
Sbjct: 328 KKVGIIGAGMMGAGIAYVSALAGIEVVLIDAA----QDSADRGKAYSEGLLDKGMKRGKV 383
Query: 289 -ELKASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTI 450
E K ++ I +TD + A+ G + E V E+ +K +V ++ ++ + I
Sbjct: 384 TEEKKAKVLGQITATTDYD-ALNGCDLIVEAVFEDPKVKAEVTAKAEAAMNADGI 437
>UniRef50_Q1IMR6 Cluster: UDP-glucose/GDP-mannose dehydrogenase;
n=33; Bacteria|Rep: UDP-glucose/GDP-mannose
dehydrogenase - Acidobacteria bacterium (strain
Ellin345)
Length = 448
Score = 36.3 bits (80), Expect = 1.0
Identities = 16/51 (31%), Positives = 32/51 (62%)
Frame = +1
Query: 70 GTVASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQI 222
GT+A+ + + + +IGIVG G +G A+LF+ ++VT +D+ +++
Sbjct: 6 GTLATELKRKIEAREARIGIVGMGYVGLPLALLFSEEKFRVTGFDIDNRKV 56
>UniRef50_Q121N3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=19;
Burkholderiales|Rep: 3-hydroxyisobutyrate dehydrogenase
- Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 298
Score = 36.3 bits (80), Expect = 1.0
Identities = 15/38 (39%), Positives = 23/38 (60%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAI 234
+G++G G +GR A S GY V VYDV A+ + + +
Sbjct: 6 VGVIGLGAMGRGIAQTLRSAGYAVHVYDVRAQAVQEFV 43
>UniRef50_Q0SCS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 284
Score = 36.3 bits (80), Expect = 1.0
Identities = 31/143 (21%), Positives = 57/143 (39%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 294
+ +G+VG G +G A +FA++G V + + ++ A++ + L G L G++
Sbjct: 7 KNVGVVGGGRMGAGIAQVFATLGSTVIIAESGDREA--AVKRVSDGLDRAHERGKL-GDV 63
Query: 295 KASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 474
+ + + V E VPE +DLK V ++ V T+
Sbjct: 64 DPATILGRVSTVAAPDALPPALDLVVEAVPELVDLKLSVLSLVEKTVSPTTVIASNTSSI 123
Query: 475 XXXXXXEGLKHKSQVIVSHPVNP 543
L +++I H NP
Sbjct: 124 SIAELGSALGDPARLIGMHFFNP 146
>UniRef50_Q041G8 Cluster: Acetoin/pyruvate dehydrogenase complex, E3
component, dihydrolipoamide dehydrogenase; n=3;
Lactobacillus|Rep: Acetoin/pyruvate dehydrogenase
complex, E3 component, dihydrolipoamide dehydrogenase -
Lactobacillus gasseri (strain ATCC 33323 / DSM 20243)
Length = 443
Score = 36.3 bits (80), Expect = 1.0
Identities = 20/54 (37%), Positives = 30/54 (55%)
Frame = +1
Query: 82 STVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDI 243
ST M K E + I+G+G IG +A +FA G +VTV D + ++ +DI
Sbjct: 149 STQAMDEKKMPENLTIIGAGYIGLEFASMFAKYGSKVTVLDHSREFLSREDDDI 202
>UniRef50_A3XHA5 Cluster: Regulatory protein; n=4;
Flavobacteriaceae|Rep: Regulatory protein -
Leeuwenhoekiella blandensis MED217
Length = 503
Score = 36.3 bits (80), Expect = 1.0
Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 4/71 (5%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLEND----GLL 282
E I +G+G IG +A + A G VT+ DV A+ +++ ED+ QL + L
Sbjct: 220 ESIIFIGAGYIGMEFAHIAARCGVDVTIVDVNARILSNFDEDLALQLQKKSEELGIKFLF 279
Query: 283 RGELKASEQFQ 315
E KA E+ +
Sbjct: 280 NAEAKAIEKLR 290
>UniRef50_A3M5D5 Cluster: Dihydrolipoamide dehydrogenase; n=1;
Acinetobacter baumannii ATCC 17978|Rep: Dihydrolipoamide
dehydrogenase - Acinetobacter baumannii (strain ATCC
17978 / NCDC KC 755)
Length = 279
Score = 36.3 bits (80), Expect = 1.0
Identities = 21/53 (39%), Positives = 32/53 (60%), Gaps = 2/53 (3%)
Frame = +1
Query: 127 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQI--TDAIEDIKYQLHTLENDGL 279
+VGSG IG +A L+ +G QVT+ D +AKQI T+ +E ++ E G+
Sbjct: 95 VVGSGAIGSEFASLYQDLGCQVTLID-LAKQILPTEDVEVAQFVRKQFEQKGM 146
>UniRef50_O83080 Cluster: D-lactate dehydrogenase; n=1; Treponema
pallidum|Rep: D-lactate dehydrogenase - Treponema
pallidum
Length = 331
Score = 36.3 bits (80), Expect = 1.0
Identities = 15/38 (39%), Positives = 26/38 (68%)
Frame = +1
Query: 91 IMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYD 204
I++ + + ++GI+G+G IG++ A LF VG QV +D
Sbjct: 139 ILSKELRCSRVGILGTGRIGQAAARLFKGVGAQVVGFD 176
>UniRef50_P72357 Cluster: D-lactate dehydrogenase; n=28;
Bacilli|Rep: D-lactate dehydrogenase - Staphylococcus
aureus
Length = 330
Score = 36.3 bits (80), Expect = 1.0
Identities = 21/93 (22%), Positives = 43/93 (46%)
Frame = +1
Query: 91 IMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLEN 270
IM+ K+ + I+G+G IG + A ++A G +T YD + D + +++
Sbjct: 139 IMSKPVKNMTVAIIGTGRIGAATAKIYAGFGATITAYDAYPNKDLDFLTYKDSVKEAIKD 198
Query: 271 DGLLRGELKASEQFQCIKGSTDLETAVKGAIFV 369
++ + A+++ + + KGAI V
Sbjct: 199 ADIISLHVPANKESYHLFDKAMFDHVKKGAILV 231
>UniRef50_Q892P7 Cluster: Dihydrolipoamide dehydrogenase; n=3;
Clostridia|Rep: Dihydrolipoamide dehydrogenase -
Clostridium tetani
Length = 589
Score = 35.9 bits (79), Expect = 1.4
Identities = 15/43 (34%), Positives = 28/43 (65%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDI 243
EKI I+G G+IG +A ++A++G +V+V + ++ ED+
Sbjct: 295 EKIAIIGGGVIGMEFAFIYANMGVEVSVIEYFDNILSMLDEDV 337
>UniRef50_Q6AA68 Cluster: UDP-glucose 6-dehydrogenase; n=3;
root|Rep: UDP-glucose 6-dehydrogenase -
Propionibacterium acnes
Length = 388
Score = 35.9 bits (79), Expect = 1.4
Identities = 32/109 (29%), Positives = 52/109 (47%), Gaps = 2/109 (1%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 297
KI + G G +G + A+L A V + D+ A+++ D+ HT D L+ E
Sbjct: 2 KIAVAGLGYVGMANAVLLAQHNSVVAI-DIDAERV-----DMVNNRHTTIVDPLI-AEYL 54
Query: 298 ASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVF--QNLDSVVD 438
A ++ +TD + A +GA FV P N D + F ++D V+D
Sbjct: 55 AHHNLD-LRATTDPQEAYRGADFVVIATPTNYDPGQNYFDTSSVDEVLD 102
>UniRef50_Q2RJ81 Cluster: 4Fe-4S ferredoxin, iron-sulfur binding
precursor; n=1; Moorella thermoacetica ATCC 39073|Rep:
4Fe-4S ferredoxin, iron-sulfur binding precursor -
Moorella thermoacetica (strain ATCC 39073)
Length = 1487
Score = 35.9 bits (79), Expect = 1.4
Identities = 15/34 (44%), Positives = 22/34 (64%)
Frame = +1
Query: 109 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVV 210
+ EK+ I+G+G G + A A GYQVT+YD +
Sbjct: 255 RKEKVAIIGAGPAGLTAAQDLALAGYQVTIYDAL 288
>UniRef50_Q2GH13 Cluster: FAD-dependent oxidoreductase; n=6;
Anaplasmataceae|Rep: FAD-dependent oxidoreductase -
Ehrlichia chaffeensis (strain Arkansas)
Length = 354
Score = 35.9 bits (79), Expect = 1.4
Identities = 15/35 (42%), Positives = 24/35 (68%)
Frame = +1
Query: 112 SEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAK 216
++K G+VG+GL+GR A+ G+QVT++D K
Sbjct: 2 NKKAGVVGAGLVGRLLALRLLHDGWQVTLFDKFGK 36
>UniRef50_Q6RK69 Cluster: D-lactate dehydrogenase; n=1;
Lactobacillus sp. MD-1|Rep: D-lactate dehydrogenase -
Lactobacillus sp. MD-1
Length = 331
Score = 35.9 bits (79), Expect = 1.4
Identities = 16/48 (33%), Positives = 24/48 (50%)
Frame = +1
Query: 82 STVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQIT 225
S M + +G++G+G IGR LF +G V YD ++IT
Sbjct: 136 SPAFMGRLISEQTVGVIGTGRIGRHAIQLFRGLGANVIAYDKYPQKIT 183
>UniRef50_Q11BV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Mesorhizobium sp. BNC1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Mesorhizobium sp. (strain BNC1)
Length = 677
Score = 35.9 bits (79), Expect = 1.4
Identities = 28/102 (27%), Positives = 49/102 (48%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 297
++G++G+G +G A+ + G V + D +T A +K L LE G L+
Sbjct: 287 RLGVIGAGTMGVGLAVSLLAAGKSVVLIDKDDLALTRASAAVKSGLARLERGGKLKEAPD 346
Query: 298 ASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNL 423
A+ + S +L +AV+ V E V E+ ++K V +L
Sbjct: 347 AA--LARLVASKEL-SAVENCEVVIEAVVESFEVKSAVLSDL 385
>UniRef50_A7BC28 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 455
Score = 35.9 bits (79), Expect = 1.4
Identities = 20/55 (36%), Positives = 35/55 (63%)
Frame = +1
Query: 76 VASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIED 240
V ST I++ ++ I+G G+IG +A L+A++G QVTV + +A +I ++D
Sbjct: 158 VDSTGILSLPQIPARLAIIGGGVIGVEFASLYATLGSQVTVIE-MAPEILPFMDD 211
>UniRef50_A6VXM3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase catalytic region; n=2; Marinomonas|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
region - Marinomonas sp. MWYL1
Length = 380
Score = 35.9 bits (79), Expect = 1.4
Identities = 15/36 (41%), Positives = 26/36 (72%)
Frame = +1
Query: 112 SEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQ 219
S+KIG++G G +G++ FA++G QV VYD + ++
Sbjct: 116 SKKIGVIGYGNVGKTVYTRFANMGCQVHVYDPIREK 151
>UniRef50_A6LMV1 Cluster: Putative uncharacterized protein
precursor; n=1; Thermosipho melanesiensis BI429|Rep:
Putative uncharacterized protein precursor - Thermosipho
melanesiensis BI429
Length = 208
Score = 35.9 bits (79), Expect = 1.4
Identities = 21/44 (47%), Positives = 29/44 (65%), Gaps = 2/44 (4%)
Frame = +1
Query: 103 KFKSEK-IGIVGSGLIGRSWAMLFASVGYQVTV-YDVVAKQITD 228
K KS+K IGI G+GL+GR+ A L + G+ V V +D K+I D
Sbjct: 109 KLKSKKNIGIYGAGLVGRALAQLLLNRGFNVVVFFDDDEKKIGD 152
>UniRef50_A3XPY3 Cluster: Putative uncharacterized protein; n=1;
Leeuwenhoekiella blandensis MED217|Rep: Putative
uncharacterized protein - Leeuwenhoekiella blandensis
MED217
Length = 262
Score = 35.9 bits (79), Expect = 1.4
Identities = 17/39 (43%), Positives = 24/39 (61%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAI 234
KIGI+G+GLIG++ A F + G+QV + D D I
Sbjct: 2 KIGIIGAGLIGKTLAKKFNAAGHQVKLGDAKGAASIDTI 40
>UniRef50_A0W3T3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Geobacter lovleyi SZ|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor - Geobacter
lovleyi SZ
Length = 285
Score = 35.9 bits (79), Expect = 1.4
Identities = 20/57 (35%), Positives = 29/57 (50%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGE 291
IG+ G+G +G A L A G++V +Y A + DA I+ L L GL+ E
Sbjct: 8 IGVAGAGSMGAGIAQLAAMAGFRVRLYARHASALADAAGRIETSLAKLHEKGLIGEE 64
>UniRef50_A3LNF8 Cluster: Kynurenine 3-monooxygenase, mitochondrial;
n=3; Saccharomycetaceae|Rep: Kynurenine 3-monooxygenase,
mitochondrial - Pichia stipitis (Yeast)
Length = 478
Score = 35.9 bits (79), Expect = 1.4
Identities = 14/33 (42%), Positives = 25/33 (75%)
Frame = +1
Query: 109 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDV 207
+ + +GIVG+GL+G A+ FA+ GY VT++++
Sbjct: 12 RHQGVGIVGAGLVGCLAALAFAAKGYSVTLFEL 44
>UniRef50_UPI00006A2AB5 Cluster: UPI00006A2AB5 related cluster; n=2;
Xenopus tropicalis|Rep: UPI00006A2AB5 UniRef100 entry -
Xenopus tropicalis
Length = 597
Score = 35.5 bits (78), Expect = 1.8
Identities = 17/56 (30%), Positives = 34/56 (60%), Gaps = 1/56 (1%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQL-HTLENDGL 279
+++ I+G+G IG +A + +VG +V V ++ + + EDI Q+ +L+ DG+
Sbjct: 319 QRLLIIGAGAIGIEFASFYRAVGSEVAVVEMAPRVLPQEDEDISAQVAASLQKDGI 374
>UniRef50_Q8FRT3 Cluster: Putative 3-hydroxybutyryl-CoA
dehydrogenase; n=2; Corynebacterineae|Rep: Putative
3-hydroxybutyryl-CoA dehydrogenase - Corynebacterium
efficiens
Length = 294
Score = 35.5 bits (78), Expect = 1.8
Identities = 30/102 (29%), Positives = 45/102 (44%), Gaps = 1/102 (0%)
Frame = +1
Query: 121 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 300
+G++G G +G A F + G VTV D+ + A E I + + RG
Sbjct: 23 VGVLGGGRMGAGIAHSFLAAGAHVTVVDINDAAVEAARERITNDI----EGSIKRGAEGT 78
Query: 301 SEQF-QCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNL 423
EQ+ + STD + V E VPE +DLK F+ +
Sbjct: 79 VEQWLDRLTLSTDTAAFADHPVVV-EAVPEIIDLKADSFRKI 119
>UniRef50_Q3AEV2 Cluster: Prephenate dehydrogenase; n=1;
Carboxydothermus hydrogenoformans Z-2901|Rep: Prephenate
dehydrogenase - Carboxydothermus hydrogenoformans
(strain Z-2901 / DSM 6008)
Length = 360
Score = 35.5 bits (78), Expect = 1.8
Identities = 18/35 (51%), Positives = 23/35 (65%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQI 222
KIGIVG GLIG S A F+ +GYQV D ++ +
Sbjct: 4 KIGIVGLGLIGGSLARAFSYLGYQVYGIDTNSQYV 38
>UniRef50_Q3IBS8 Cluster: Iron-sulfur-binding protein, glutamate
synthase subunit; n=3; uncultured sulfate-reducing
bacterium|Rep: Iron-sulfur-binding protein, glutamate
synthase subunit - uncultured sulfate-reducing bacterium
Length = 576
Score = 35.5 bits (78), Expect = 1.8
Identities = 17/36 (47%), Positives = 22/36 (61%)
Frame = +1
Query: 109 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAK 216
K EKI ++G+G G S A A GY VTVY+ + K
Sbjct: 139 KDEKIAVIGAGPSGMSCAYQLARRGYPVTVYESLPK 174
>UniRef50_Q0F8T2 Cluster: Salicylate hydroxylase; n=1; alpha
proteobacterium HTCC2255|Rep: Salicylate hydroxylase -
alpha proteobacterium HTCC2255
Length = 386
Score = 35.5 bits (78), Expect = 1.8
Identities = 20/65 (30%), Positives = 37/65 (56%), Gaps = 2/65 (3%)
Frame = +1
Query: 112 SEKIGIVGSGLIGRSWAMLFASVGYQVTVYD--VVAKQITDAIEDIKYQLHTLENDGLLR 285
++KIG++G G+ G + A+ FA G QVT+Y+ +V ++ I+ ++ L G+
Sbjct: 5 NKKIGVIGGGIGGLASAIAFAKFGSQVTLYEKALVISEVGAGIQISANGINVLTKLGIYP 64
Query: 286 GELKA 300
LK+
Sbjct: 65 DYLKS 69
>UniRef50_Q0B0P7 Cluster: NADP oxidoreductase, coenzyme
F420-dependent; n=1; Syntrophomonas wolfei subsp. wolfei
str. Goettingen|Rep: NADP oxidoreductase, coenzyme
F420-dependent - Syntrophomonas wolfei subsp. wolfei
(strain Goettingen)
Length = 298
Score = 35.5 bits (78), Expect = 1.8
Identities = 15/44 (34%), Positives = 29/44 (65%), Gaps = 1/44 (2%)
Frame = +1
Query: 115 EKIGIVGSGLIGRSWAMLFASVGYQVT-VYDVVAKQITDAIEDI 243
EKIGI+G+G++G + ++ + GY++T V D+ ++ +E I
Sbjct: 3 EKIGIIGAGVVGTAVGVVLKNKGYEITGVQDIKSESTQQLVERI 46
>UniRef50_A3DJQ8 Cluster: NADH:flavin oxidoreductase/NADH oxidase;
n=1; Clostridium thermocellum ATCC 27405|Rep:
NADH:flavin oxidoreductase/NADH oxidase - Clostridium
thermocellum (strain ATCC 27405 / DSM 1237)
Length = 645
Score = 35.5 bits (78), Expect = 1.8
Identities = 22/79 (27%), Positives = 41/79 (51%), Gaps = 2/79 (2%)
Frame = +1
Query: 76 VASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQ- 252
+A+ ++ + + + IVG GL+G + A G +VT+ D++ + D I ++
Sbjct: 495 IATKLLKEGQDTGQNVIIVGGGLVGCETGLHLAEKGKKVTIIDMLPEVAQDVIFMARFSL 554
Query: 253 LHTLENDGL-LRGELKASE 306
L L+N G+ G LK +E
Sbjct: 555 LEALKNKGIETYGGLKLTE 573
>UniRef50_Q0V6D4 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 508
Score = 35.5 bits (78), Expect = 1.8
Identities = 18/42 (42%), Positives = 27/42 (64%)
Frame = +1
Query: 109 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAI 234
K EKI ++G G +G A+LFA VG V++ D ++Q DA+
Sbjct: 3 KFEKIAMIGCGSMGGGMALLFAEVGVHVSLSD-PSEQAMDAV 43
>UniRef50_O28262 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 281
Score = 35.5 bits (78), Expect = 1.8
Identities = 40/148 (27%), Positives = 65/148 (43%)
Frame = +1
Query: 118 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 297
K+ ++G+GL+GR A+ AS ++V + DV K + A E I +L
Sbjct: 2 KVFVIGAGLMGRGIAIAIAS-KHEVVLQDVSEKALEAAREQIPEEL-------------- 46
Query: 298 ASEQFQCIKGSTDLETAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 477
I+ +T LE VK V E V E+L+ K +V + ++ + N
Sbjct: 47 ----LSKIEFTTTLE-KVKDCDIVMEAVFEDLNTKVEVLREVERLT--NAPLCSNTSVIS 99
Query: 478 XXXXXEGLKHKSQVIVSHPVNPPYYVPL 561
E L S+ + H +NPP+ +PL
Sbjct: 100 VDDIAERLDSPSRFLGVHWMNPPHVMPL 127
>UniRef50_Q485S6 Cluster: Putative D-amino acid dehydrogenase, small
subunit; n=1; Colwellia psychrerythraea 34H|Rep:
Putative D-amino acid dehydrogenase, small subunit -
Colwellia psychrerythraea (strain 34H / ATCC BAA-681)
(Vibriopsychroerythus)
Length = 427
Score = 35.1 bits (77), Expect = 2.4
Identities = 16/42 (38%), Positives = 27/42 (64%), Gaps = 1/42 (2%)
Frame = +1
Query: 82 STVI-MASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYD 204
STV+ K + + ++G+G+IG + A+ S+GYQVT+ D
Sbjct: 2 STVVDQEGNNKQQTVAVIGAGIIGINCALELQSLGYQVTLLD 43
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 839,024,056
Number of Sequences: 1657284
Number of extensions: 16996688
Number of successful extensions: 47326
Number of sequences better than 10.0: 323
Number of HSP's better than 10.0 without gapping: 45308
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 47199
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 79932179145
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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