Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= MFBP10_F_F17
(895 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9VXI1 Cluster: CG9914-PA; n=5; Diptera|Rep: CG9914-PA ... 161 2e-38
UniRef50_UPI0000588BF0 Cluster: PREDICTED: similar to 3-hydroxya... 139 8e-32
UniRef50_Q9Y2S2 Cluster: Lambda-crystallin homolog; n=30; Coelom... 136 5e-31
UniRef50_A7SBT1 Cluster: Predicted protein; n=2; Nematostella ve... 116 6e-25
UniRef50_Q1RLR0 Cluster: LOC570274 protein; n=4; Clupeocephala|R... 106 7e-22
UniRef50_Q9D221 Cluster: Adult male hypothalamus cDNA, RIKEN ful... 98 2e-19
UniRef50_Q2CEL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 82 2e-14
UniRef50_A4R503 Cluster: Putative uncharacterized protein; n=3; ... 80 9e-14
UniRef50_A5G288 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 79 1e-13
UniRef50_A5A8P0 Cluster: Putative uncharacterized protein; n=3; ... 77 8e-13
UniRef50_Q6SEY0 Cluster: 3-hydroxyacyl-CoA dehydrogenase domain ... 72 2e-11
UniRef50_Q98LG2 Cluster: Mll1034 protein; n=5; Alphaproteobacter... 71 3e-11
UniRef50_Q160J3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 71 4e-11
UniRef50_Q5KYB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=6... 70 7e-11
UniRef50_Q5L0D2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 69 2e-10
UniRef50_Q9HKW7 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenas... 69 2e-10
UniRef50_A1FMQ0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 68 3e-10
UniRef50_A1B801 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 67 5e-10
UniRef50_O29062 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A... 67 7e-10
UniRef50_Q0FUQ2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 66 1e-09
UniRef50_A5N111 Cluster: Hbd2; n=5; Clostridiales|Rep: Hbd2 - Cl... 66 1e-09
UniRef50_Q11EZ3 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 66 2e-09
UniRef50_A6CP14 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 65 2e-09
UniRef50_O28011 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; A... 65 2e-09
UniRef50_Q9RZ10 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 65 3e-09
UniRef50_Q978T2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5; A... 64 3e-09
UniRef50_Q93QG7 Cluster: Hydroxyacyl-CoA dehydrogenase; n=1; Bre... 64 5e-09
UniRef50_O29077 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; c... 64 6e-09
UniRef50_Q97UK9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; S... 63 1e-08
UniRef50_Q5LTH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 62 2e-08
UniRef50_Q39LC4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; B... 61 3e-08
UniRef50_Q7WLK3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 61 4e-08
UniRef50_A3VGB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 60 1e-07
UniRef50_Q8XI27 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase N... 59 1e-07
UniRef50_Q73Q34 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 59 1e-07
UniRef50_Q2W2Y1 Cluster: Glyoxysomal fatty acid beta-oxidation m... 59 1e-07
UniRef50_Q24N80 Cluster: Putative uncharacterized protein; n=1; ... 59 1e-07
UniRef50_Q1GEJ8 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 59 2e-07
UniRef50_A0GEI2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 58 2e-07
UniRef50_O30218 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A... 58 2e-07
UniRef50_Q2B4D1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 58 3e-07
UniRef50_A1IEK7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 58 3e-07
UniRef50_Q0C7S2 Cluster: Putative uncharacterized protein; n=1; ... 58 4e-07
UniRef50_A6C4K6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 57 5e-07
UniRef50_A3YAS5 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 57 5e-07
UniRef50_Q9HRI4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7; c... 57 5e-07
UniRef50_UPI00005102FD Cluster: COG1250: 3-hydroxyacyl-CoA dehyd... 57 7e-07
UniRef50_Q396V2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=9; B... 57 7e-07
UniRef50_A2TU34 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 56 1e-06
UniRef50_A1FNB9 Cluster: 3-hydroxyacyl-CoA dehydrogenase precurs... 56 1e-06
UniRef50_Q39HR3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=24; ... 55 2e-06
UniRef50_A0PRD1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase FadB... 55 2e-06
UniRef50_Q9UX37 Cluster: 3-hydroxyacyl-CoA-dehydrogenase; n=4; S... 55 2e-06
UniRef50_Q1DAC1 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 54 4e-06
UniRef50_Q5V0V6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 54 4e-06
UniRef50_UPI000050F939 Cluster: COG1250: 3-hydroxyacyl-CoA dehyd... 54 5e-06
UniRef50_Q7WCB1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 54 5e-06
UniRef50_Q11E57 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 54 5e-06
UniRef50_Q5UWD9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; c... 54 5e-06
UniRef50_A0RUN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 54 5e-06
UniRef50_P76083 Cluster: Probable 3-hydroxybutyryl-CoA dehydroge... 54 5e-06
UniRef50_Q5P039 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; P... 54 6e-06
UniRef50_A5D5N2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 54 6e-06
UniRef50_A3STE1 Cluster: Putative hydroxlacyl-CoA dehydrogenase;... 54 6e-06
UniRef50_A0LSM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 54 6e-06
UniRef50_A1CC71 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 53 9e-06
UniRef50_Q16836 Cluster: Hydroxyacyl-coenzyme A dehydrogenase, m... 53 9e-06
UniRef50_Q988C8 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1... 53 1e-05
UniRef50_Q67SZ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; S... 53 1e-05
UniRef50_Q397D0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 53 1e-05
UniRef50_A3M445 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 53 1e-05
UniRef50_O29815 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A... 53 1e-05
UniRef50_Q9KBD3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=8... 52 2e-05
UniRef50_Q891F6 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=3... 52 2e-05
UniRef50_A1I839 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 52 2e-05
UniRef50_Q12D24 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 52 2e-05
UniRef50_A2QXC7 Cluster: Contig An11c0270, complete genome. prec... 52 2e-05
UniRef50_Q8G825 Cluster: Possible butyryl-CoA dehydrogenase; n=2... 52 3e-05
UniRef50_UPI000023E2B1 Cluster: hypothetical protein FG00090.1; ... 51 3e-05
UniRef50_A1SSP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 51 3e-05
UniRef50_Q5V357 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; H... 51 3e-05
UniRef50_Q0SEM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 51 5e-05
UniRef50_A0VLT7 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 50 6e-05
UniRef50_Q2J5F5 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 50 8e-05
UniRef50_O69856 Cluster: Fatty acid oxidation complex alpha-subu... 50 8e-05
UniRef50_Q28KL8 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 50 8e-05
UniRef50_A4YDR4 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 50 8e-05
UniRef50_Q7VRZ0 Cluster: Probable enoyl-CoA hydratase/3-hydroxya... 50 1e-04
UniRef50_Q28UL9 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 50 1e-04
UniRef50_Q5LPZ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 49 1e-04
UniRef50_Q9YBW6 Cluster: 3-hydroxyacyl-CoA dehydrogenase/3-hydro... 49 1e-04
UniRef50_Q9XA30 Cluster: Putative 3-Hydroxyacyl-CoA dehydrogenas... 49 2e-04
UniRef50_Q11TH9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 49 2e-04
UniRef50_Q6V1N6 Cluster: PlmT8; n=1; Streptomyces sp. HK803|Rep:... 48 2e-04
UniRef50_Q0RVG8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; R... 48 2e-04
UniRef50_A4ALU9 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like pr... 48 2e-04
UniRef50_A1SPQ6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 48 2e-04
UniRef50_Q89HA7 Cluster: Blr6087 protein; n=6; Proteobacteria|Re... 48 3e-04
UniRef50_Q1IMY8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 48 3e-04
UniRef50_O44608 Cluster: Hydroxy-acyl-coa dehydrogenase protein ... 48 3e-04
UniRef50_Q4J6T7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 48 3e-04
UniRef50_Q0LZ25 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 48 4e-04
UniRef50_A6ERZ1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 48 4e-04
UniRef50_A4FKS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 48 4e-04
UniRef50_Q0UZL9 Cluster: Putative uncharacterized protein; n=1; ... 48 4e-04
UniRef50_P34439 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenas... 48 4e-04
UniRef50_A3U7V8 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 47 6e-04
UniRef50_Q84T13 Cluster: L-3-hydroxyacyl-CoA dehydrogenase subun... 47 6e-04
UniRef50_A7PEM6 Cluster: Chromosome chr11 scaffold_13, whole gen... 47 6e-04
UniRef50_Q7D836 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 47 7e-04
UniRef50_Q47M90 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 47 7e-04
UniRef50_Q4J598 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD bi... 47 7e-04
UniRef50_Q876X5 Cluster: Dehydrogenase; n=7; Pezizomycotina|Rep:... 47 7e-04
UniRef50_Q4PFL4 Cluster: Putative uncharacterized protein; n=1; ... 46 0.001
UniRef50_A2QA05 Cluster: Catalytic activity:; n=4; Trichocomacea... 46 0.001
UniRef50_A7D676 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 46 0.001
UniRef50_Q5LKF7 Cluster: Fatty oxidation complex, alpha subunit;... 46 0.001
UniRef50_Q2S2J8 Cluster: Fatty oxidation complex, alpha subunit;... 46 0.001
UniRef50_Q0FUM2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 46 0.001
UniRef50_A5VHQ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 46 0.001
UniRef50_A5IDB6 Cluster: 3-hydroxyacyl CoA dehydrogenase; n=9; G... 46 0.001
UniRef50_A0QZR0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 46 0.001
UniRef50_Q3A7N5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 46 0.002
UniRef50_Q46MP3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 45 0.002
UniRef50_Q9ADL9 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase; ... 45 0.002
UniRef50_A4SW21 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 45 0.002
UniRef50_Q2VHK2 Cluster: Oxidoreductase; n=11; Lactobacillales|R... 45 0.003
UniRef50_Q2UUZ5 Cluster: RIB40 genomic DNA, SC009; n=4; Trichoco... 45 0.003
UniRef50_A2QCM7 Cluster: Catalytic activity: precursor; n=5; Tri... 44 0.004
UniRef50_Q4J0Z7 Cluster: 3-hydroxyacyl-CoA dehydrogenase, C-term... 44 0.005
UniRef50_A0Z5J4 Cluster: Enoyl-CoA hydratase; n=2; unclassified ... 44 0.005
UniRef50_Q7RZ80 Cluster: Putative uncharacterized protein NCU043... 44 0.005
UniRef50_UPI00006A277A Cluster: UPI00006A277A related cluster; n... 44 0.007
UniRef50_A6X670 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 44 0.007
UniRef50_Q9RUA4 Cluster: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA... 43 0.009
UniRef50_Q5HKI5 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 43 0.009
UniRef50_Q1EVV0 Cluster: Dihydrolipoyl dehydrogenase; n=6; Clost... 43 0.009
UniRef50_A1WHE6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; V... 43 0.009
UniRef50_Q1IIH2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 43 0.012
UniRef50_Q9AF94 Cluster: 3-hydroxyacyl-CoA-dehydrogenase; n=1; A... 42 0.016
UniRef50_A4FGV2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 42 0.016
UniRef50_P45856 Cluster: Probable 3-hydroxybutyryl-CoA dehydroge... 42 0.016
UniRef50_A3YFA8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 42 0.021
UniRef50_A5V325 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 42 0.028
UniRef50_A0HAN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 42 0.028
UniRef50_Q39NP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 41 0.037
UniRef50_Q1GGC1 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 41 0.037
UniRef50_A1SEZ9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 41 0.037
UniRef50_A4RUY4 Cluster: Predicted protein; n=5; cellular organi... 41 0.037
UniRef50_Q0LRY2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 41 0.049
UniRef50_A1IFR8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 41 0.049
UniRef50_A0JVH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 41 0.049
UniRef50_A7S4Z9 Cluster: Predicted protein; n=1; Nematostella ve... 41 0.049
UniRef50_Q02A28 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 40 0.065
UniRef50_A6GC68 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 40 0.065
UniRef50_A0JTB4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5; A... 40 0.065
UniRef50_UPI00015BAF7B Cluster: 3-hydroxyacyl-CoA dehydrogenase,... 40 0.086
UniRef50_A4SW27 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7; B... 40 0.086
UniRef50_A0IJE2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 40 0.086
UniRef50_P45364 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 40 0.086
UniRef50_Q88X11 Cluster: NADH peroxidase; n=1; Lactobacillus pla... 40 0.11
UniRef50_Q1YHC5 Cluster: Putative 3-hydroxybutyryl-CoA dehydroge... 40 0.11
UniRef50_A3ZYI9 Cluster: Fatty oxidation complex, alpha subunit ... 40 0.11
UniRef50_A1SQH4 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 40 0.11
UniRef50_Q6MHW5 Cluster: Glucose-inhibited division protein; n=1... 39 0.15
UniRef50_Q5LVG3 Cluster: Enoyl-CoA hydratase/isomerase/3-hydroxy... 39 0.15
UniRef50_Q5LVD0 Cluster: Enoyl-CoA hydratase/isomerase/3-hydroxy... 39 0.15
UniRef50_Q4Q939 Cluster: Trifunctional enzyme alpha subunit, mit... 39 0.15
UniRef50_O29090 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A... 39 0.15
UniRef50_Q8RC01 Cluster: UDP-N-acetyl-D-mannosaminuronate dehydr... 39 0.20
UniRef50_Q39TJ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like; n... 39 0.20
UniRef50_Q0C0V2 Cluster: Oxidoreductase, FAD-binding; n=2; Prote... 39 0.20
UniRef50_A3D4X7 Cluster: FAD dependent oxidoreductase; n=3; Shew... 38 0.26
UniRef50_Q8G3X6 Cluster: Possible class I pyridine nucleotide-di... 38 0.35
UniRef50_Q8FRT3 Cluster: Putative 3-hydroxybutyryl-CoA dehydroge... 38 0.35
UniRef50_Q1ATL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 38 0.35
UniRef50_P14218 Cluster: Dihydrolipoyl dehydrogenase; n=65; cell... 38 0.35
UniRef50_Q8YB80 Cluster: 3-HYDROXYBUTYRYL-COA DEHYDROGENASE; n=3... 38 0.46
UniRef50_Q8CXB6 Cluster: UDP-glucose:GDP-mannose dehydrogenase; ... 38 0.46
UniRef50_Q88YA7 Cluster: Bifunctional protein: amino acid aminot... 38 0.46
UniRef50_Q4A6P9 Cluster: Putative mercuric reductase; n=1; Mycop... 38 0.46
UniRef50_Q0SUA0 Cluster: Pyridine nucleotide-disulphide oxidored... 38 0.46
UniRef50_A0J682 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 38 0.46
UniRef50_Q45223 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=9... 38 0.46
UniRef50_O34324 Cluster: Dihydrolipoyl dehydrogenase; n=13; Baci... 38 0.46
UniRef50_P38169 Cluster: Kynurenine 3-monooxygenase; n=4; Saccha... 38 0.46
UniRef50_Q82W31 Cluster: Phosphoribosylaminoimidazole carboxylas... 37 0.60
UniRef50_Q1FP37 Cluster: NADH:flavin oxidoreductase/NADH oxidase... 37 0.60
UniRef50_A6P2M7 Cluster: Putative uncharacterized protein; n=2; ... 37 0.60
UniRef50_A5WEP3 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 37 0.60
UniRef50_A4XMY3 Cluster: Prephenate dehydrogenase; n=1; Caldicel... 37 0.60
UniRef50_A4WWF6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 37 0.60
UniRef50_Q6D2L7 Cluster: Fatty acid oxidation complex subunit al... 37 0.60
UniRef50_UPI000018F68E Cluster: hypothetical protein Rm378p142; ... 37 0.80
UniRef50_Q9X0U4 Cluster: Glutamate synthase, beta subunit; n=5; ... 37 0.80
UniRef50_Q8CX86 Cluster: UDP-glucose:GDP-mannose dehydrogenase; ... 37 0.80
UniRef50_Q9N5G1 Cluster: Dehydrogenases, short chain protein 15;... 37 0.80
UniRef50_Q0UJN7 Cluster: Predicted protein; n=1; Phaeosphaeria n... 37 0.80
UniRef50_Q89SH2 Cluster: Blr2428 protein; n=7; Rhizobiales|Rep: ... 36 1.1
UniRef50_Q834J0 Cluster: Dihydrolipoyl dehydrogenase; n=3; Lacto... 36 1.1
UniRef50_Q1IMR6 Cluster: UDP-glucose/GDP-mannose dehydrogenase; ... 36 1.1
UniRef50_Q121N3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 36 1.1
UniRef50_Q11BV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 36 1.1
UniRef50_Q041G8 Cluster: Acetoin/pyruvate dehydrogenase complex,... 36 1.1
UniRef50_A3XHA5 Cluster: Regulatory protein; n=4; Flavobacteriac... 36 1.1
UniRef50_A3M5D5 Cluster: Dihydrolipoamide dehydrogenase; n=1; Ac... 36 1.1
UniRef50_Q8U0F8 Cluster: NDP-sugar dehydrogenase; n=4; Thermococ... 36 1.1
UniRef50_O83080 Cluster: D-lactate dehydrogenase; n=1; Treponema... 36 1.1
UniRef50_P35484 Cluster: Dihydrolipoyl dehydrogenase; n=3; Achol... 36 1.1
UniRef50_Q892P7 Cluster: Dihydrolipoamide dehydrogenase; n=3; Cl... 36 1.4
UniRef50_Q67L77 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 36 1.4
UniRef50_Q2RJ81 Cluster: 4Fe-4S ferredoxin, iron-sulfur binding ... 36 1.4
UniRef50_Q2GH13 Cluster: FAD-dependent oxidoreductase; n=6; Anap... 36 1.4
UniRef50_Q8GP50 Cluster: Eps11H; n=13; Lactobacillales|Rep: Eps1... 36 1.4
UniRef50_Q6RK69 Cluster: D-lactate dehydrogenase; n=1; Lactobaci... 36 1.4
UniRef50_Q0SEV8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 36 1.4
UniRef50_A7BC28 Cluster: Putative uncharacterized protein; n=1; ... 36 1.4
UniRef50_A6VXM3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 36 1.4
UniRef50_A6LMV1 Cluster: Putative uncharacterized protein precur... 36 1.4
UniRef50_A4BGI3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; R... 36 1.4
UniRef50_A3ZZK1 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1... 36 1.4
UniRef50_A3XPY3 Cluster: Putative uncharacterized protein; n=1; ... 36 1.4
UniRef50_A0W3T3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 36 1.4
UniRef50_A3LNF8 Cluster: Kynurenine 3-monooxygenase, mitochondri... 36 1.4
UniRef50_UPI00006A2AB5 Cluster: UPI00006A2AB5 related cluster; n... 36 1.8
UniRef50_Q8FX64 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 36 1.8
UniRef50_Q5NW50 Cluster: DitN-like 3-hydroxyacyl-CoA dehydrogena... 36 1.8
UniRef50_Q3AEV2 Cluster: Prephenate dehydrogenase; n=1; Carboxyd... 36 1.8
UniRef50_Q3IBS8 Cluster: Iron-sulfur-binding protein, glutamate ... 36 1.8
UniRef50_Q1YTH7 Cluster: Fatty oxidation complex, alpha subunit;... 36 1.8
UniRef50_Q1IUZ3 Cluster: UDP-glucose/GDP-mannose dehydrogenase; ... 36 1.8
UniRef50_Q0F8T2 Cluster: Salicylate hydroxylase; n=1; alpha prot... 36 1.8
UniRef50_Q0B0P7 Cluster: NADP oxidoreductase, coenzyme F420-depe... 36 1.8
UniRef50_A6WDS7 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 36 1.8
UniRef50_A3DJQ8 Cluster: NADH:flavin oxidoreductase/NADH oxidase... 36 1.8
UniRef50_Q0V6D4 Cluster: Putative uncharacterized protein; n=1; ... 36 1.8
UniRef50_Q97HK2 Cluster: 3-Hydroxyacyl-CoA dehydrogenase; n=1; C... 35 2.4
UniRef50_Q62DG4 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 35 2.4
UniRef50_Q485S6 Cluster: Putative D-amino acid dehydrogenase, sm... 35 2.4
UniRef50_Q28N18 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 35 2.4
UniRef50_Q1NHB4 Cluster: Fatty oxidation complex, alpha subunit;... 35 2.4
UniRef50_Q05FN5 Cluster: Dihydrodipicolinate synthase; n=1; Cand... 35 2.4
UniRef50_A5IXT8 Cluster: D-lactate dehydrogenase; n=3; Mycoplasm... 35 2.4
UniRef50_P77212 Cluster: Probable pyridine nucleotide-disulfide ... 35 2.4
UniRef50_P53267 Cluster: DASH complex subunit DAM1; n=2; Sacchar... 35 2.4
UniRef50_Q8E285 Cluster: Pyridine nucleotide-disulphide oxidored... 35 3.2
UniRef50_Q83EI9 Cluster: Thiamine biosynthesis oxidoreductase Th... 35 3.2
UniRef50_Q7WIS8 Cluster: Putative enoyl-CoA isomerase; n=2; Bord... 35 3.2
UniRef50_Q7NCM9 Cluster: Glr2949 protein; n=1; Gloeobacter viola... 35 3.2
UniRef50_Q6AA68 Cluster: UDP-glucose 6-dehydrogenase; n=3; root|... 35 3.2
UniRef50_Q2J6P6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=10; ... 35 3.2
UniRef50_A1IDF2 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 35 3.2
UniRef50_A0V9H2 Cluster: 2-dehydropantoate 2-reductase precursor... 35 3.2
UniRef50_Q5KBI5 Cluster: Short chain 3-hydroxyacyl-CoA dehydroge... 35 3.2
UniRef50_P72357 Cluster: D-lactate dehydrogenase; n=28; Bacilli|... 35 3.2
UniRef50_Q8F125 Cluster: Cell-division inhibitor; n=3; Bacteria|... 34 4.3
UniRef50_Q5FGZ4 Cluster: Dihydrolipoyl dehydrogenase; n=11; Rick... 34 4.3
UniRef50_Q0RL76 Cluster: Putative 3-hydroxybutyryl-CoA dehydroge... 34 4.3
UniRef50_Q0FK50 Cluster: Putative uncharacterized protein; n=1; ... 34 4.3
UniRef50_A5IAB6 Cluster: Pyridine nucleotide-disulfide oxidoredu... 34 4.3
UniRef50_O17761 Cluster: Putative uncharacterized protein ech-8;... 34 4.3
UniRef50_A7RTC7 Cluster: Predicted protein; n=1; Nematostella ve... 34 4.3
UniRef50_P12045 Cluster: Phosphoribosylaminoimidazole carboxylas... 34 4.3
UniRef50_UPI0000510280 Cluster: COG1249: Pyruvate/2-oxoglutarate... 34 5.6
UniRef50_Q9RW59 Cluster: Dehydrogenase, putative; n=2; Deinococc... 34 5.6
UniRef50_Q97PL8 Cluster: Oxidoreductase, pyridine nucleotide-dis... 34 5.6
UniRef50_Q4FKW7 Cluster: D-amino-acid dehydrogenase small chain;... 34 5.6
UniRef50_Q24PW4 Cluster: Dihydrolipoyl dehydrogenase; n=1; Desul... 34 5.6
UniRef50_Q1YK26 Cluster: Phosphoribosylaminoimidazole carboxylas... 34 5.6
UniRef50_Q128W2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 34 5.6
UniRef50_Q11ME9 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 34 5.6
UniRef50_A7DM30 Cluster: Multi-sensor hybrid histidine kinase; n... 34 5.6
UniRef50_A1SPH4 Cluster: UDP-glucose/GDP-mannose dehydrogenase; ... 34 5.6
UniRef50_A0YDQ2 Cluster: NADP oxidoreductase, coenzyme F420-depe... 34 5.6
UniRef50_A0HBX6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 34 5.6
UniRef50_Q92D17 Cluster: Lin1004 protein; n=10; Bacilli|Rep: Lin... 33 7.4
UniRef50_Q8XN08 Cluster: D-lactate dehydrogenase; n=4; Firmicute... 33 7.4
UniRef50_Q8A2W9 Cluster: Dihydrolipoyl dehydrogenase; n=7; Bacte... 33 7.4
UniRef50_Q3SL16 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 33 7.4
UniRef50_Q392L7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=9... 33 7.4
UniRef50_Q30V14 Cluster: D-isomer specific 2-hydroxyacid dehydro... 33 7.4
UniRef50_Q49111 Cluster: Dihydrolipoamide dehydrogenase; n=7; ro... 33 7.4
UniRef50_Q1LBV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 33 7.4
UniRef50_Q1DAE6 Cluster: NADP oxidoreductase, coenzyme F420-depe... 33 7.4
UniRef50_A6M0T5 Cluster: Amine oxidase; n=6; Clostridium|Rep: Am... 33 7.4
UniRef50_A6CF61 Cluster: Soluble pyridine nucleotide transhydrog... 33 7.4
UniRef50_A5V9L0 Cluster: FAD dependent oxidoreductase precursor;... 33 7.4
UniRef50_A4WXD4 Cluster: Dimethylmenaquinone methyltransferase; ... 33 7.4
UniRef50_A3UGW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 33 7.4
UniRef50_A0UKE0 Cluster: FAD dependent oxidoreductase precursor;... 33 7.4
UniRef50_A0M4X2 Cluster: Kynurenine-3-monooxygenase-like protein... 33 7.4
UniRef50_A0LI43 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 33 7.4
UniRef50_Q23ZE9 Cluster: FAD dependent oxidoreductase family pro... 33 7.4
UniRef50_Q22X26 Cluster: Putative uncharacterized protein; n=1; ... 33 7.4
UniRef50_A7TI21 Cluster: Putative uncharacterized protein; n=1; ... 33 7.4
UniRef50_Q8TWI7 Cluster: UDP-N-acetylmuramoylalanine-D-glutamate... 33 7.4
UniRef50_A3DNE3 Cluster: FAD-dependent pyridine nucleotide-disul... 33 7.4
UniRef50_P75393 Cluster: Dihydrolipoyl dehydrogenase; n=6; Mycop... 33 7.4
UniRef50_UPI000038D9FE Cluster: COG1249: Pyruvate/2-oxoglutarate... 33 9.8
UniRef50_UPI000023D207 Cluster: hypothetical protein FG05450.1; ... 33 9.8
UniRef50_Q98N90 Cluster: Mll0243 protein; n=1; Mesorhizobium lot... 33 9.8
UniRef50_Q836Q9 Cluster: 6-phosphogluconate dehydrogenase, decar... 33 9.8
UniRef50_Q6F8G8 Cluster: Putative uncharacterized protein; n=2; ... 33 9.8
UniRef50_Q3JZL6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 33 9.8
UniRef50_Q7X2D3 Cluster: D-amino acid oxidase; n=1; Arthrobacter... 33 9.8
UniRef50_Q4AI87 Cluster: FAD-dependent pyridine nucleotide-disul... 33 9.8
UniRef50_Q222Q6 Cluster: FAD dependent oxidoreductase precursor;... 33 9.8
UniRef50_Q18CC1 Cluster: E3 component of acetoin dehydrogenase e... 33 9.8
UniRef50_Q08VR6 Cluster: NADP oxidoreductase, coenzyme f420-depe... 33 9.8
UniRef50_Q06BB6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 33 9.8
UniRef50_Q03CK2 Cluster: Predicted dinucleotide-binding enzyme; ... 33 9.8
UniRef50_A6NVP0 Cluster: Putative uncharacterized protein; n=1; ... 33 9.8
UniRef50_A6GD93 Cluster: UDP-N-acetylmuramoylalanine--D-glutamat... 33 9.8
UniRef50_A3PFJ2 Cluster: NAD binding site:D-amino acid oxidase; ... 33 9.8
UniRef50_Q7RJ67 Cluster: Putative uncharacterized protein PY0339... 33 9.8
UniRef50_A7T9W4 Cluster: Predicted protein; n=1; Nematostella ve... 33 9.8
UniRef50_A7EL57 Cluster: Putative uncharacterized protein; n=1; ... 33 9.8
UniRef50_Q8TZS4 Cluster: Glutamate synthase; n=78; cellular orga... 33 9.8
UniRef50_Q4J9Z6 Cluster: Conserved Crenarchaeal protein; n=3; Su... 33 9.8
UniRef50_A3H9B3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 33 9.8
UniRef50_P48638 Cluster: Glutathione reductase; n=57; Bacteria|R... 33 9.8
>UniRef50_Q9VXI1 Cluster: CG9914-PA; n=5; Diptera|Rep: CG9914-PA -
Drosophila melanogaster (Fruit fly)
Length = 315
Score = 161 bits (392), Expect = 2e-38
Identities = 76/141 (53%), Positives = 101/141 (71%)
Frame = +1
Query: 118 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG 297
K+EK+GIVGSGLIGRSW+MLFASVGYQV +YD++ +Q++ A+ + +L LE GLLRG
Sbjct: 4 KNEKVGIVGSGLIGRSWSMLFASVGYQVVLYDILPEQVSTALTATQKELQDLEAKGLLRG 63
Query: 298 ELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXX 477
+L A++QF CI G+ DL VKGA+FVQEC+PE LDLKK +++ LD+VV NTI
Sbjct: 64 KLTAAQQFACISGTNDLKELVKGAIFVQECIPERLDLKKALYKQLDAVVGPNTILSSSTS 123
Query: 478 XXXXXXXXEGLKHKSQVIVSH 540
LK+K+ V+VSH
Sbjct: 124 TFLPSLFSADLKNKANVLVSH 144
Score = 106 bits (254), Expect = 9e-22
Identities = 51/85 (60%), Positives = 57/85 (67%)
Frame = +2
Query: 566 PLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLXXXX 745
PL EIVPAPWTKPE KKTR +MEEIGQ+PV+L+REI+GF LNRIQYAIL+E WRL
Sbjct: 153 PLVEIVPAPWTKPEWVKKTRALMEEIGQKPVTLSREIEGFALNRIQYAILNETWRLVEAG 212
Query: 746 XXXXXXXXXXMSEGLGXEICIFGVL 820
MS GLG G L
Sbjct: 213 ILNVKDIDSVMSNGLGPRYAFLGPL 237
Score = 40.3 bits (90), Expect = 0.065
Identities = 17/27 (62%), Positives = 19/27 (70%)
Frame = +1
Query: 808 FWGALXTAHLNAEGMQSYIDXYGETIY 888
F G L TAHLNAEGM +Y + Y TIY
Sbjct: 233 FLGPLETAHLNAEGMANYFERYSNTIY 259
>UniRef50_UPI0000588BF0 Cluster: PREDICTED: similar to
3-hydroxyacyl-coa dehyrogenase; n=5; Coelomata|Rep:
PREDICTED: similar to 3-hydroxyacyl-coa dehyrogenase -
Strongylocentrotus purpuratus
Length = 316
Score = 139 bits (337), Expect = 8e-32
Identities = 67/141 (47%), Positives = 90/141 (63%)
Frame = +1
Query: 118 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG 297
+S+KIGIVGSGLIGRSWAM+FAS G+ VT++D+ Q+++A++ IK QL L G+LRG
Sbjct: 2 ESQKIGIVGSGLIGRSWAMIFASAGFSVTIFDIEPSQVSNALKLIKSQLEELSESGMLRG 61
Query: 298 ELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXX 477
L QF IKGS + A+ GA FVQECV E L++K+KVF ++ V D I
Sbjct: 62 TLSVEAQFALIKGSNSMEEALAGASFVQECVFEKLEVKQKVFSEMEQYVSDGAILSSSSS 121
Query: 478 XXXXXXXXEGLKHKSQVIVSH 540
E LK ++Q I+SH
Sbjct: 122 CIMPSQFTENLKRRNQCIISH 142
Score = 86.2 bits (204), Expect = 1e-15
Identities = 41/85 (48%), Positives = 48/85 (56%)
Frame = +2
Query: 566 PLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLXXXX 745
PL EI+PAPWT +TR IME +GQ PV+L +E+ GF NRIQYAI+ EVWRL
Sbjct: 151 PLVEIIPAPWTDQSAIDRTRTIMESVGQVPVTLKKEVPGFAANRIQYAIIAEVWRLVEGG 210
Query: 746 XXXXXXXXXXMSEGLGXEICIFGVL 820
MS GLG G L
Sbjct: 211 VLSADDMDKVMSAGLGLRYAFLGPL 235
Score = 35.9 bits (79), Expect = 1.4
Identities = 15/26 (57%), Positives = 19/26 (73%)
Frame = +1
Query: 808 FWGALXTAHLNAEGMQSYIDXYGETI 885
F G L HLNAEGMQSY++ Y ++I
Sbjct: 231 FLGPLEVMHLNAEGMQSYMERYTQSI 256
>UniRef50_Q9Y2S2 Cluster: Lambda-crystallin homolog; n=30;
Coelomata|Rep: Lambda-crystallin homolog - Homo sapiens
(Human)
Length = 319
Score = 136 bits (330), Expect = 5e-31
Identities = 65/135 (48%), Positives = 88/135 (65%)
Frame = +1
Query: 136 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASE 315
IVGSG+IGRSWAMLFAS G+QV +YD+ +QI +A+E+I+ ++ LE G L+G L E
Sbjct: 11 IVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGSLKGSLSVEE 70
Query: 316 QFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXX 495
Q I G ++ AV+GA+ +QECVPE+L+LKKK+F LDS++DD I
Sbjct: 71 QLSLISGCPNIQEAVEGAMHIQECVPEDLELKKKIFAQLDSIIDDRVILSSSTSCLMPSK 130
Query: 496 XXEGLKHKSQVIVSH 540
GL H Q IV+H
Sbjct: 131 LFAGLVHVKQCIVAH 145
Score = 77.8 bits (183), Expect = 3e-13
Identities = 37/85 (43%), Positives = 48/85 (56%)
Frame = +2
Query: 566 PLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLXXXX 745
PL E+VP P T P +T +M++IGQ P+ + +E+ GFVLNR+QYAI+ E WRL
Sbjct: 154 PLVELVPHPETAPTTVDRTHALMKKIGQCPMRVQKEVAGFVLNRLQYAIISEAWRLVEEG 213
Query: 746 XXXXXXXXXXMSEGLGXEICIFGVL 820
MSEGLG G L
Sbjct: 214 IVSPSDLDLVMSEGLGMRYAFIGPL 238
Score = 36.3 bits (80), Expect = 1.1
Identities = 17/26 (65%), Positives = 17/26 (65%)
Frame = +1
Query: 808 FWGALXTAHLNAEGMQSYIDXYGETI 885
F G L T HLNAEGM SY D Y E I
Sbjct: 234 FIGPLETMHLNAEGMLSYCDRYSEGI 259
>UniRef50_A7SBT1 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 322
Score = 116 bits (280), Expect = 6e-25
Identities = 61/149 (40%), Positives = 88/149 (59%), Gaps = 3/149 (2%)
Frame = +1
Query: 103 MASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLEND 282
M S + K+ ++GSGLIGR+W+ LF+S GY V +YD V+ Q+ +A E I QL LE+
Sbjct: 1 MTSSTEKGKVAVIGSGLIGRAWSTLFSSAGYHVALYDTVSSQLVNAKEAIISQLQELESK 60
Query: 283 GLLRGE--LKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDN- 453
LL+G A E F+ + + DL A+ G +VQEC PENL+LKKKVFQNL++ + +
Sbjct: 61 ELLKGRHCKTAQEAFKLVTTTDDLPQALNGVFYVQECTPENLELKKKVFQNLEATLSSSE 120
Query: 454 TIXXXXXXXXXXXXXXEGLKHKSQVIVSH 540
I E L+ + + IV+H
Sbjct: 121 VILASSTSCIMPSKFTESLQLRQRCIVAH 149
Score = 82.6 bits (195), Expect = 1e-14
Identities = 35/83 (42%), Positives = 52/83 (62%)
Frame = +2
Query: 566 PLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLXXXX 745
PL E++PAPWT V ++T ++M++IGQ PV L +E +GF++NR+QYA++ E WRL
Sbjct: 158 PLVEVIPAPWTDASVIEQTIKLMKDIGQSPVLLKKETNGFIVNRLQYALIAEAWRLVEEG 217
Query: 746 XXXXXXXXXXMSEGLGXEICIFG 814
M+EGLG + G
Sbjct: 218 ICSPEDVDTTMTEGLGLRYSLIG 240
>UniRef50_Q1RLR0 Cluster: LOC570274 protein; n=4; Clupeocephala|Rep:
LOC570274 protein - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 327
Score = 106 bits (255), Expect = 7e-22
Identities = 57/144 (39%), Positives = 84/144 (58%)
Frame = +1
Query: 109 SKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGL 288
S K + I +VGSGLIGRSWAM+F S GY+V +YD Q + AI +I+ QL L+ +
Sbjct: 14 SSLKEKIITVVGSGLIGRSWAMVFLSGGYKVKLYDNKPGQASGAIAEIRKQLEELQQAKM 73
Query: 289 LRGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXX 468
LRG L A+EQ + DL A+ GA FVQE V E+L+ K+ VF ++ +V ++ I
Sbjct: 74 LRGNLSATEQLSRLSSHEDLQQALDGAFFVQESVFEDLEAKQSVFHAVEELVSESVILSS 133
Query: 469 XXXXXXXXXXXEGLKHKSQVIVSH 540
++++++ IVSH
Sbjct: 134 STSCLMPSNVFSQVQNRTRCIVSH 157
Score = 74.9 bits (176), Expect = 2e-12
Identities = 37/82 (45%), Positives = 45/82 (54%)
Frame = +2
Query: 569 LXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLXXXXX 748
L E+VP P T P V + +M ++GQ PV L +EIDGF LNR+QYAI+ E WRL
Sbjct: 167 LVELVPHPETLPAVMEVAYSLMTDVGQAPVRLRKEIDGFALNRVQYAIIAESWRLVQDGV 226
Query: 749 XXXXXXXXXMSEGLGXEICIFG 814
MSEGLG G
Sbjct: 227 ISVKDIDLVMSEGLGMRYAFIG 248
>UniRef50_Q9D221 Cluster: Adult male hypothalamus cDNA, RIKEN
full-length enriched library, clone:A230106J09
product:crystallin, lamda 1, full insert sequence; n=3;
Euarchontoglires|Rep: Adult male hypothalamus cDNA,
RIKEN full-length enriched library, clone:A230106J09
product:crystallin, lamda 1, full insert sequence - Mus
musculus (Mouse)
Length = 140
Score = 98.3 bits (234), Expect = 2e-19
Identities = 46/83 (55%), Positives = 62/83 (74%)
Frame = +1
Query: 136 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASE 315
IVGSGLIGRSWAMLFAS G++V +YD+ +QITDA+E+I+ ++ +LE G L+G L A
Sbjct: 11 IVGSGLIGRSWAMLFASGGFKVKLYDIEQQQITDALENIRKEMKSLEQSGSLKGSLSAER 70
Query: 316 QFQCIKGSTDLATAVKGAVFVQE 384
Q I G +LA AV+GAV +Q+
Sbjct: 71 QLSLISGCGNLAEAVEGAVHIQQ 93
>UniRef50_Q2CEL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Rhodobacteraceae|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Oceanicola granulosus HTCC2516
Length = 312
Score = 81.8 bits (193), Expect = 2e-14
Identities = 49/138 (35%), Positives = 72/138 (52%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 306
K+ I+G+GLIG+SWA+ FA G VT++D A+ + L LE LL GE
Sbjct: 3 KVAIIGAGLIGQSWAIAFARGGCAVTLHDRDHAVADRALAVLPDALAALERMDLLGGET- 61
Query: 307 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 486
A I ++DLA AV+GA+ VQE PE L++K+ VF LD D + +
Sbjct: 62 ADAVGARIDAASDLADAVRGAIHVQENTPETLEVKRSVFAQLDDAADADAVIASSSSALL 121
Query: 487 XXXXXEGLKHKSQVIVSH 540
+GL ++ +V+H
Sbjct: 122 PSAFTDGLAGAARCLVAH 139
Score = 67.3 bits (157), Expect = 5e-10
Identities = 33/88 (37%), Positives = 46/88 (52%)
Frame = +2
Query: 551 HLITYPLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWR 730
HL+ P E+VP P T E +TR +M IGQ P+ +RE++GFV+NR+Q A+LDE +
Sbjct: 145 HLV--PAVELVPGPQTSAETVARTRALMSSIGQSPIETSREVEGFVMNRLQGALLDEAFA 202
Query: 731 LXXXXXXXXXXXXXXMSEGLGXEICIFG 814
L M +GL G
Sbjct: 203 LVEQGLASPADIDTAMRDGLARRWTFLG 230
>UniRef50_A4R503 Cluster: Putative uncharacterized protein; n=3;
Sordariomycetes|Rep: Putative uncharacterized protein -
Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 330
Score = 79.8 bits (188), Expect = 9e-14
Identities = 50/141 (35%), Positives = 77/141 (54%), Gaps = 3/141 (2%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 306
K+ I+G G IG SWA LF + G +V+ +DV + E + L L + GL++
Sbjct: 6 KVAIIGCGSIGASWAALFLAQGLEVSAFDVNPSAESFLRELVANALPVLSSLGLVKSSQA 65
Query: 307 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 486
+ I+ +TD+ATA+K A FVQE PE LD K+K+F+ + ++VD +TI
Sbjct: 66 TAAD---IEFTTDMATALKNASFVQENGPERLDFKQKLFRGVANLVDPDTIIATSSSGLT 122
Query: 487 XXXXXEGL--KHK-SQVIVSH 540
+GL +HK +V+V H
Sbjct: 123 CSSIQQGLEAQHKPERVVVGH 143
Score = 45.2 bits (102), Expect = 0.002
Identities = 28/88 (31%), Positives = 40/88 (45%)
Frame = +2
Query: 551 HLITYPLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWR 730
HLI PL E+V T +T EE+G++ V + +E+ G V NR+Q A++ EV
Sbjct: 149 HLI--PLVEVVGGEQTSQATISRTMGFYEEVGKKAVHIKKEVVGHVANRLQAALMREVMY 206
Query: 731 LXXXXXXXXXXXXXXMSEGLGXEICIFG 814
L MS G G + G
Sbjct: 207 LVQEGVADVSDIDRAMSNGPGLRWGVMG 234
>UniRef50_A5G288 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=2; Proteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Acidiphilium cryptum (strain JF-5)
Length = 312
Score = 79.4 bits (187), Expect = 1e-13
Identities = 43/111 (38%), Positives = 66/111 (59%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 306
KI +VG+GL+G +WA++FA G+ V VYD V AI I +L TLE GL+
Sbjct: 2 KIAVVGAGLVGSAWAIVFARAGHDVAVYDAVEGGADRAIGLIGDRLKTLEEVGLIEDAAA 61
Query: 307 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
A ++ ++ + LA AV A ++QE V E ++ K+++F LD+VV T+
Sbjct: 62 AGQR---VRVAASLADAVADAAYIQESVFETVEQKRQIFAALDAVVGPETL 109
Score = 77.8 bits (183), Expect = 3e-13
Identities = 35/83 (42%), Positives = 47/83 (56%)
Frame = +2
Query: 566 PLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLXXXX 745
P+ E+VPAPWT ++ R +ME +GQ+PV LTREI+GF LNR+Q +L E W+L
Sbjct: 145 PVVELVPAPWTAAATVQRVRALMESVGQEPVELTREIEGFALNRLQGLLLAEAWKLVADG 204
Query: 746 XXXXXXXXXXMSEGLGXEICIFG 814
+S GLG G
Sbjct: 205 IMSVEDVDRTVSAGLGLRWSFMG 227
>UniRef50_A5A8P0 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 284
Score = 76.6 bits (180), Expect = 8e-13
Identities = 35/83 (42%), Positives = 46/83 (55%)
Frame = +2
Query: 566 PLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLXXXX 745
PL E+VPAPWT + + EIM + Q+PV L +E+ GFV+NR+Q+A+L E WRL
Sbjct: 121 PLTELVPAPWTSQDTVDRAAEIMRSVKQEPVKLKKEVLGFVVNRLQFALLAETWRLVADG 180
Query: 746 XXXXXXXXXXMSEGLGXEICIFG 814
MS GLG G
Sbjct: 181 VIGVNDVDAVMSAGLGPRYAFNG 203
Score = 64.1 bits (149), Expect = 5e-09
Identities = 31/112 (27%), Positives = 58/112 (51%)
Frame = +1
Query: 205 VYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASEQFQCIKGSTDLATAVKGAVFVQE 384
+YD+ KQ+ A+E+++ L L+ GL RG L A E + +T L +K A+++QE
Sbjct: 1 MYDISEKQLQVALENVEKNLRKLDEHGLQRGNLSADEALLRVSTTTSLNEVMKNAIYMQE 60
Query: 385 CVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXXEGLKHKSQVIVSH 540
E+L+ + + ++ +D + D TI +GL +K + ++ H
Sbjct: 61 SALEDLNFRIQFYKVIDEIADPTTILASSTSTIPASKFTDGLINKERCLIVH 112
>UniRef50_Q6SEY0 Cluster: 3-hydroxyacyl-CoA dehydrogenase domain
protein; n=1; uncultured bacterium 582|Rep:
3-hydroxyacyl-CoA dehydrogenase domain protein -
uncultured bacterium 582
Length = 322
Score = 72.1 bits (169), Expect = 2e-11
Identities = 44/137 (32%), Positives = 68/137 (49%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
+ +VG+GLIG WA++FA G+QVT+ D+ ++ A + + QL LE L
Sbjct: 17 VSVVGAGLIGCGWAIVFARAGWQVTLQDIDLAKLQGAPKVLAVQLRMLEQHDLCADPAGI 76
Query: 310 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 489
+ I +DL TAV +VQEC PE L LK+++F LD++ TI
Sbjct: 77 LAR---ISYESDLKTAVCEVDYVQECGPEVLGLKQELFSELDALTPPETILASSTSGLMA 133
Query: 490 XXXXEGLKHKSQVIVSH 540
L + + +V+H
Sbjct: 134 SQFSAHLAGRHRALVAH 150
Score = 65.3 bits (152), Expect = 2e-09
Identities = 32/88 (36%), Positives = 49/88 (55%)
Frame = +2
Query: 551 HLITYPLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWR 730
HL+ P+ EI P+ WT PE+ + ++M +GQ PV++ +EI GF+LNR+Q A+L+E R
Sbjct: 156 HLV--PVVEISPSEWTDPEIVRVVVDVMTGVGQTPVTVQKEIPGFLLNRLQGALLNEALR 213
Query: 731 LXXXXXXXXXXXXXXMSEGLGXEICIFG 814
L + +GLG G
Sbjct: 214 LAQGGFATVEDIDKTVRDGLGLRWSFMG 241
>UniRef50_Q98LG2 Cluster: Mll1034 protein; n=5;
Alphaproteobacteria|Rep: Mll1034 protein - Rhizobium
loti (Mesorhizobium loti)
Length = 315
Score = 71.3 bits (167), Expect = 3e-11
Identities = 46/137 (33%), Positives = 67/137 (48%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
+ IVGSG IGR+WA+ FA G+ V ++D A + I+ L L + LLRG+
Sbjct: 4 VAIVGSGFIGRAWAISFARAGHDVRMWDQSPAATGGARDYIEGVLGDLAANDLLRGQ-SV 62
Query: 310 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 489
I DLA A+ A VQE PENLD+K++VF +D + TI
Sbjct: 63 DTVLGRIATVGDLAEALADAAHVQENTPENLDVKREVFSLIDRLAGPQTIIASSTSALLP 122
Query: 490 XXXXEGLKHKSQVIVSH 540
+ L+ + + +V H
Sbjct: 123 SKFTDHLQGRHRCLVVH 139
Score = 67.7 bits (158), Expect = 4e-10
Identities = 27/56 (48%), Positives = 40/56 (71%)
Frame = +2
Query: 566 PLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRL 733
P E+VPAPWT E +KTR + + G P+ + RE+DGF++NR+Q A+L+E +RL
Sbjct: 148 PAAEVVPAPWTSAETLEKTRAFLIDAGHAPLVMRRELDGFIMNRLQGALLEEAFRL 203
>UniRef50_Q160J3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Roseobacter denitrificans OCh 114|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Roseobacter
denitrificans (strain ATCC 33942 / OCh 114)
(Erythrobactersp. (strain OCh 114)) (Roseobacter
denitrificans)
Length = 331
Score = 70.9 bits (166), Expect = 4e-11
Identities = 35/88 (39%), Positives = 48/88 (54%)
Frame = +2
Query: 551 HLITYPLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWR 730
HL+ PL E+VPAPWT +++ IGQ P+ L REIDGFV+NR+Q A+L E +
Sbjct: 160 HLV--PLVEVVPAPWTAQSAVDTVHDLLSAIGQVPILLNREIDGFVVNRLQGALLREAFH 217
Query: 731 LXXXXXXXXXXXXXXMSEGLGXEICIFG 814
L +S+GLG + G
Sbjct: 218 LLDQGVASRKDIDKAISDGLGLRWSLMG 245
Score = 51.6 bits (118), Expect = 3e-05
Identities = 33/137 (24%), Positives = 61/137 (44%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
+ I+G GLIG++WA +F G +VT+YD + + A + ++ L+ E
Sbjct: 19 VAIIGCGLIGQAWATVFLRAGMRVTLYDAASGLVEQAKAQVIERMTEFARFDLVTHETLE 78
Query: 310 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 489
I+ + L AV A ++QE E LD+K ++ + +D + +
Sbjct: 79 RAPAH-IELADTLEDAVSAADYIQESGSEALDVKIELTREIDRFAAPHVVIGSSTSGITA 137
Query: 490 XXXXEGLKHKSQVIVSH 540
E +K + + +V H
Sbjct: 138 SRYSETIKGRERCLVVH 154
>UniRef50_Q5KYB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=6;
Bacillaceae|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Geobacillus kaustophilus
Length = 287
Score = 70.1 bits (164), Expect = 7e-11
Identities = 41/108 (37%), Positives = 67/108 (62%), Gaps = 3/108 (2%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 303
E++ +VGSG++GR A + A G+Q T+ D+ +Q+ A ++I ++ G+ RG+L
Sbjct: 3 ERLVVVGSGVMGRGIAYVGAVGGFQTTLVDIKQEQLESAQKEIA----SIFEQGVARGKL 58
Query: 304 KASEQFQC---IKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDS 438
SE+ + + S DLA AV+ A V E VPE L+LKK+VF+ +D+
Sbjct: 59 TDSERQEAEARLSYSLDLAAAVRDADLVIEAVPEKLELKKQVFETIDA 106
>UniRef50_Q5L0D2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Geobacillus kaustophilus
Length = 281
Score = 68.9 bits (161), Expect = 2e-10
Identities = 42/113 (37%), Positives = 59/113 (52%)
Frame = +1
Query: 121 SEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGE 300
+E I ++G+G++G A A VG V +YDV + + + + L G L E
Sbjct: 2 AETIAVIGAGVMGSGIAQTAAMVGKTVYLYDVSEAALQNGLASAEKSLRRFVKTGGL-SE 60
Query: 301 LKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
+A I+ + DLA AV+GA V E VPENL LKK VFQ LD + + I
Sbjct: 61 PEARAALGRIRSTVDLAEAVRGADVVIEAVPENLALKKDVFQQLDQLAKPDAI 113
>UniRef50_Q9HKW7 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenase;
n=2; Thermoplasmatales|Rep: Probable 3-hydroxyacyl-CoA
dehydrogenase - Thermoplasma acidophilum
Length = 291
Score = 68.9 bits (161), Expect = 2e-10
Identities = 47/138 (34%), Positives = 69/138 (50%), Gaps = 3/138 (2%)
Frame = +1
Query: 136 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIK---YQLHTLENDGLLRGELK 306
+VGSG++G+ A +FA GY VT+ DV + +A+ IK Y L L G + E +
Sbjct: 8 VVGSGVMGQGIAQVFARSGYPVTIIDVRDDILANAVRSIKEGRYGLMNLVKKGTMT-ESE 66
Query: 307 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 486
+ I+ ST + + A V E VPENLDLK+KVF +++ V +N I
Sbjct: 67 VDKIMGKIRTSTSYGS-LSDADIVVEAVPENLDLKRKVFIDIEKNVSENAIIASNTSGIT 125
Query: 487 XXXXXEGLKHKSQVIVSH 540
+ LK K + I H
Sbjct: 126 IAEIAQDLKKKDRAIGMH 143
>UniRef50_A1FMQ0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=3; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Pseudomonas putida W619
Length = 320
Score = 68.1 bits (159), Expect = 3e-10
Identities = 33/83 (39%), Positives = 45/83 (54%)
Frame = +2
Query: 566 PLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLXXXX 745
PL E+ PAPWT+ EV + EI GQ PV L+REI GF+LNR+Q A+L+E ++L
Sbjct: 157 PLVELCPAPWTESEVMVRAHEIYTAAGQSPVVLSREIHGFLLNRVQAAVLNECFKLHEEG 216
Query: 746 XXXXXXXXXXMSEGLGXEICIFG 814
+ +GL G
Sbjct: 217 FASSEDIDRVLKDGLALRWSFMG 239
Score = 65.3 bits (152), Expect = 2e-09
Identities = 41/138 (29%), Positives = 72/138 (52%), Gaps = 1/138 (0%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTL-ENDGLLRGELK 306
I IVG+GLIGR+WA++FA G+ V ++D+ + + ++ I+ +L+ L E D L L
Sbjct: 14 IAIVGAGLIGRAWAIVFARAGHPVRLHDMDLQTMQNSHAYIEARLNELAEFDLLNDAPLT 73
Query: 307 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 486
+ C+ DLA A++ V VQE V E ++ K +F +D++ + I
Sbjct: 74 VLARITCV---PDLADALRDVVLVQENVRETVEAKIDIFSRMDALAPKDAILASSTSWLP 130
Query: 487 XXXXXEGLKHKSQVIVSH 540
+ L + + +V+H
Sbjct: 131 ASEFTKDLPGRGRCVVAH 148
>UniRef50_A1B801 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Rhodobacteraceae|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Paracoccus denitrificans (strain Pd 1222)
Length = 311
Score = 67.3 bits (157), Expect = 5e-10
Identities = 45/137 (32%), Positives = 65/137 (47%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
I IVG+GLIGR+WA +FA G+ V V+D+ + + DI + G + A
Sbjct: 4 IAIVGAGLIGRAWAFVFARAGFDVRVWDLDPQVLERLDGDIAAMVAQTAPFGQAGADPDA 63
Query: 310 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 489
+ I+ DLA A+ GA VQE PE L +K+++F LD + I
Sbjct: 64 TA--ARIRAVPDLAGALDGAELVQESGPEVLAIKRELFARLDGLAAAGVILASSSSALMA 121
Query: 490 XXXXEGLKHKSQVIVSH 540
EGL S+ +V H
Sbjct: 122 SAFAEGLPGASRCLVGH 138
Score = 66.1 bits (154), Expect = 1e-09
Identities = 35/88 (39%), Positives = 45/88 (51%)
Frame = +2
Query: 551 HLITYPLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWR 730
HL+ P+ EI PAP+T P + + R+I GQ PV L REIDGF+LNR+Q +L E R
Sbjct: 144 HLV--PVVEIAPAPFTDPVITARARDIYARAGQVPVMLKREIDGFILNRLQAVVLAESLR 201
Query: 731 LXXXXXXXXXXXXXXMSEGLGXEICIFG 814
L + GLG G
Sbjct: 202 LIEQGYVDPQGLDDTIRHGLGRRWAFMG 229
>UniRef50_O29062 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 315
Score = 66.9 bits (156), Expect = 7e-10
Identities = 36/111 (32%), Positives = 59/111 (53%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 306
K+ +G+G +G SWA LFA G V VYD + + A I + TL ++ E
Sbjct: 4 KVACIGAGTVGASWASLFAWRGCDVAVYDPFPEALNRAEASIARTVSTL-SEIFSGSEDD 62
Query: 307 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
+K + +L A+KGA +VQE E L++K+ +F+ +D++ + TI
Sbjct: 63 VKSALSRVKFTENLEEALKGAYYVQESAVEKLEVKRDLFEKMDAIAEPETI 113
Score = 46.4 bits (105), Expect = 0.001
Identities = 28/89 (31%), Positives = 41/89 (46%)
Frame = +2
Query: 551 HLITYPLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWR 730
HLI PL E+VP T +KT E ME +G++P+ + +++ G V NR+ A+ E
Sbjct: 147 HLI--PLVEVVPRKQTDESCTEKTVEFMERMGKKPIVVKKDVPGMVANRLAAALWREAVN 204
Query: 731 LXXXXXXXXXXXXXXMSEGLGXEICIFGV 817
L + G G I GV
Sbjct: 205 LVYQGIATPEEIDVAVKYGPGIRWAITGV 233
>UniRef50_Q0FUQ2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Alphaproteobacteria|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Roseovarius sp. HTCC2601
Length = 316
Score = 66.1 bits (154), Expect = 1e-09
Identities = 35/88 (39%), Positives = 49/88 (55%)
Frame = +2
Query: 551 HLITYPLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWR 730
HL+ P+ EI PAP+T EV+++T M E GQ PV + +E++GFVLNR+Q A+L E+
Sbjct: 146 HLL--PVTEICPAPFTSAEVSERTTAFMRECGQIPVRIKKEVEGFVLNRMQAALLVEMLT 203
Query: 731 LXXXXXXXXXXXXXXMSEGLGXEICIFG 814
L +SEG G G
Sbjct: 204 LLREDLIDARDIDAIISEGFGLRWAFLG 231
Score = 64.1 bits (149), Expect = 5e-09
Identities = 38/111 (34%), Positives = 57/111 (51%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 306
KI I+GSG+IG SWA+++A G V +Y+ A++ ++ L + LLR
Sbjct: 5 KIAILGSGVIGASWAIVYARSGCDVAIYERSEAFRDSAMQRLESSL--ASSASLLRDGET 62
Query: 307 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
+ I L AV GA FV EC+ ENLD K+++F L+ + I
Sbjct: 63 VQDVLARITLHDTLEAAVAGADFVHECIVENLDSKRQIFAALNDAAEPEAI 113
>UniRef50_A5N111 Cluster: Hbd2; n=5; Clostridiales|Rep: Hbd2 -
Clostridium kluyveri DSM 555
Length = 319
Score = 66.1 bits (154), Expect = 1e-09
Identities = 37/139 (26%), Positives = 63/139 (45%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 303
+ + ++G+G +G L A G V ++ + IK L LE G ++ +
Sbjct: 4 KNVAVLGTGTMGNGIVQLCAESGLNVNMFGRTDASLERGFTSIKTSLKNLEEKGKIKTNI 63
Query: 304 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 483
+ E + IKG + AV+G FV EC+ E+L+LK++VF LD + I
Sbjct: 64 -SKEILKRIKGVKTIEEAVEGVDFVIECIAEDLELKQEVFSKLDEICAPEVILASNTSGL 122
Query: 484 XXXXXXEGLKHKSQVIVSH 540
KH +V+++H
Sbjct: 123 SPTDIAINTKHPERVVIAH 141
Score = 41.5 bits (93), Expect = 0.028
Identities = 20/52 (38%), Positives = 31/52 (59%)
Frame = +2
Query: 566 PLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDE 721
PL E+VP T + T + +E IG++ V + +E GF+ NR+Q A+L E
Sbjct: 150 PLVEVVPGKHTDSKTVDITMDWIEHIGKKGVKMRKECLGFIGNRLQLALLRE 201
>UniRef50_Q11EZ3 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=3; Bacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Mesorhizobium sp. (strain BNC1)
Length = 318
Score = 65.7 bits (153), Expect = 2e-09
Identities = 42/137 (30%), Positives = 66/137 (48%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
I IVG+G IG ++A+LFAS G V ++D + A +++ +L L L
Sbjct: 13 ISIVGAGSIGVAFAVLFASRGASVRIWDALPDAFDRAANELRSRLEMLAKASALSEP--P 70
Query: 310 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 489
E I +LA A+ GA VQEC PEN+DLK +F+ L + D+ +
Sbjct: 71 DEISSRISWHRNLAEALDGADLVQECAPENIDLKVDLFRWLADLTPDHVVLASSSSALIA 130
Query: 490 XXXXEGLKHKSQVIVSH 540
++ + +V+V H
Sbjct: 131 SLIAPDIEIRRRVLVGH 147
Score = 51.2 bits (117), Expect = 3e-05
Identities = 26/83 (31%), Positives = 40/83 (48%)
Frame = +2
Query: 566 PLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLXXXX 745
P+ E+VP+P T + + EI +PV + RE++GF+ NR+Q A+L E + L
Sbjct: 156 PVIEVVPSPETAQAIIDRAFEIYRNSHLKPVLVRREVEGFIFNRLQGAVLREAYCLVRDG 215
Query: 746 XXXXXXXXXXMSEGLGXEICIFG 814
M GLG + G
Sbjct: 216 IASVDDIDEVMRSGLGRRWSVIG 238
>UniRef50_A6CP14 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Bacillus sp. SG-1|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Bacillus sp. SG-1
Length = 293
Score = 65.3 bits (152), Expect = 2e-09
Identities = 38/113 (33%), Positives = 64/113 (56%), Gaps = 3/113 (2%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 303
+K+ ++GSG++GR A + A G+Q T+ DV +Q+ A + +L ++ G+ RG+L
Sbjct: 13 DKLVVIGSGVMGRGIAYVSAVGGFQTTLVDVEQRQLDSA----QGELTSIFQKGVDRGKL 68
Query: 304 KASEQFQC---IKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDN 453
E + STD+A AV+ A V E VPE ++KK VF+ +D ++
Sbjct: 69 SKEESTDAQGRLSFSTDMAKAVESADLVIEAVPEKTEIKKAVFEKIDEYAQES 121
>UniRef50_O28011 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 668
Score = 65.3 bits (152), Expect = 2e-09
Identities = 39/125 (31%), Positives = 66/125 (52%)
Frame = +1
Query: 85 VASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQL 264
V + M + + + + ++G+GL+G A + A GY VT+ D+ + + + IK L
Sbjct: 5 VKQVINMDVRERIKTVAVLGAGLMGHGIAEVCAMAGYNVTMRDIKQEFVDRGMNMIKESL 64
Query: 265 HTLENDGLLRGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVV 444
LE G ++ A E IK + DL AVK A V E VPE +++KK+V++ +D +
Sbjct: 65 AKLEQKGKIKS---AEEVLSRIKPTVDLEEAVKDADLVIEAVPEVVEIKKQVWEEVDKLA 121
Query: 445 DDNTI 459
+ I
Sbjct: 122 KPDCI 126
Score = 36.7 bits (81), Expect = 0.80
Identities = 15/45 (33%), Positives = 27/45 (60%)
Frame = +2
Query: 569 LXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQ 703
L E++ T EV E ++ IG+ PV + +++ GF++NR+Q
Sbjct: 163 LVEVIRGEKTSDEVMDLLVEFVKSIGKTPVRVEKDVPGFIVNRVQ 207
>UniRef50_Q9RZ10 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
n=11; Bacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase,
putative - Deinococcus radiodurans
Length = 347
Score = 64.9 bits (151), Expect = 3e-09
Identities = 39/117 (33%), Positives = 57/117 (48%)
Frame = +1
Query: 109 SKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGL 288
S + + + GSG++G A A G+ V +YD+ I A E + +L L
Sbjct: 50 SSMSIKTVTVCGSGVLGSQIAFQTAFHGFDVHLYDINDAAIAKARETLG-KLQARYQQDL 108
Query: 289 LRGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
+ + F I TD+A AVKG V E +PEN+D+K+K + L V D NTI
Sbjct: 109 KVDAQQTGDAFARISFFTDIAEAVKGVDLVIEAIPENMDIKRKFYNQLGEVADPNTI 165
>UniRef50_Q978T2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5;
Archaea|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Thermoplasma volcanium
Length = 659
Score = 64.5 bits (150), Expect = 3e-09
Identities = 41/138 (29%), Positives = 62/138 (44%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 306
K+ ++GSG++G A A GY V + D+ + A +I L L G L + K
Sbjct: 5 KVTVIGSGIMGHGIAETIALAGYDVNLEDISDDVLAKAKAEIDASLDRLVKSGKLSDKTK 64
Query: 307 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 486
+ T + +VK A V E VPE LD+K++VF LD ++ I
Sbjct: 65 VLGRIHYF---TSIPESVKDADLVIEAVPEILDIKRQVFAQLDQSTKEDAILATNTSNIR 121
Query: 487 XXXXXEGLKHKSQVIVSH 540
EG+K K +V+ H
Sbjct: 122 LTEIAEGVKKKGKVVGMH 139
Score = 35.9 bits (79), Expect = 1.4
Identities = 14/48 (29%), Positives = 30/48 (62%)
Frame = +2
Query: 557 ITYPLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 700
+ L E++ + +T+ EV + + ++IG+ P+ + ++ GFV+NRI
Sbjct: 145 VVLKLVEVIRSDYTEDEVFEAVYDFSKKIGKIPIKVYKDTPGFVVNRI 192
>UniRef50_Q93QG7 Cluster: Hydroxyacyl-CoA dehydrogenase; n=1;
Brevibacterium sp. HCU|Rep: Hydroxyacyl-CoA
dehydrogenase - Brevibacterium sp. HCU
Length = 316
Score = 64.1 bits (149), Expect = 5e-09
Identities = 36/110 (32%), Positives = 60/110 (54%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
+GI G+G IG ++A+LFA G+ V ++D + + I ++ L+ LL
Sbjct: 7 VGIFGAGSIGTAFALLFADAGFAVRIFDPDPSALERSRHVIDQRITELQRFTLLASN--P 64
Query: 310 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
SE + I+ + TA GA+ VQE PE++ K+ +F++L +V D TI
Sbjct: 65 SEVRELIEIVSSARTAASGAILVQEAGPEDVQTKQHIFEDLTAVTSDETI 114
Score = 48.0 bits (109), Expect = 3e-04
Identities = 25/80 (31%), Positives = 39/80 (48%)
Frame = +2
Query: 575 EIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLXXXXXXX 754
E+V P T+ + + ++ E+ G V + RE+DGFV NRIQ A+L E + L
Sbjct: 152 ELVGNPSTEEQTILRAGQLYEQAGLSAVRVNREVDGFVFNRIQGAVLREAYALVGAEIID 211
Query: 755 XXXXXXXMSEGLGXEICIFG 814
+ +GLG + G
Sbjct: 212 PMDLDTLVQDGLGLRWSVAG 231
>UniRef50_O29077 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyacyl-CoA dehydrogenase
- Archaeoglobus fulgidus
Length = 295
Score = 63.7 bits (148), Expect = 6e-09
Identities = 43/113 (38%), Positives = 59/113 (52%), Gaps = 3/113 (2%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDV---VAKQITDAIEDIKYQLHTLENDGLLRGE 300
IG+VG+G++G A + A GY V + DV V K+ + IE + L L G + E
Sbjct: 9 IGVVGAGVMGHGIAQVAARTGYDVVMVDVSEEVLKKAMELIESGPFGLRRLVEKGKM-SE 67
Query: 301 LKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
+A I+ ST L A+K A F+ E V E DLKKK+F LD + TI
Sbjct: 68 DEAKAVMARIRTSTSLE-ALKDADFIIEAVTEKADLKKKIFAELDRICKPETI 119
>UniRef50_Q97UK9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2;
Sulfolobus|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Sulfolobus solfataricus
Length = 384
Score = 62.9 bits (146), Expect = 1e-08
Identities = 43/139 (30%), Positives = 67/139 (48%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 303
+KIG+VG+G +G A + A Y V+V D+ + A E I L+ G ++
Sbjct: 4 KKIGVVGAGTMGHGIAEVSALANYNVSVVDISWDFLNRAKERIMESLNKFYEKGQIKE-- 61
Query: 304 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 483
K + + I+ ST ++ A FV E VPE ++LK+KVF+ LDS+ +T
Sbjct: 62 KPEDIMKRIEFSTSY-DVMRDADFVIEAVPEIIELKRKVFETLDSITPSHTFLASNTSSI 120
Query: 484 XXXXXXEGLKHKSQVIVSH 540
E K K ++I H
Sbjct: 121 PISTIAEVTKRKEKIIGMH 139
Score = 41.1 bits (92), Expect = 0.037
Identities = 20/54 (37%), Positives = 32/54 (59%)
Frame = +2
Query: 569 LXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWR 730
L EIVP+ +T E + T ++ +++ + PV L E+ GFV NRI ++ E R
Sbjct: 149 LVEIVPSKYTSDETIEVTIDLAKKMNKIPVKLKVEVPGFVSNRIFLRLMQEACR 202
>UniRef50_Q5LTH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=16; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase family protein -
Silicibacter pomeroyi
Length = 487
Score = 62.1 bits (144), Expect = 2e-08
Identities = 44/138 (31%), Positives = 64/138 (46%), Gaps = 3/138 (2%)
Frame = +1
Query: 136 IVGSGLIGRSWAMLFASVGYQVTVYDV---VAKQITDAIEDIKYQLHTLENDGLLRGELK 306
I+G G+IG WA F G+ V V+D ++I + + + + L L +D L E K
Sbjct: 6 IIGGGVIGGGWAARFLLNGWDVRVFDPDPEAERKIGEVLANARRSLPGL-SDMPLPPEGK 64
Query: 307 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 486
S DL AV GA ++QE VPE LDLK KV++++ D I
Sbjct: 65 LSFH-------ADLGEAVTGAAWIQESVPERLDLKLKVYRSIQEACDPGAILGSSTSGFK 117
Query: 487 XXXXXEGLKHKSQVIVSH 540
EG Q++V+H
Sbjct: 118 PSELQEGALRPGQIVVTH 135
Score = 45.2 bits (102), Expect = 0.002
Identities = 21/55 (38%), Positives = 33/55 (60%)
Frame = +2
Query: 566 PLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWR 730
PL E+V P PE+ ++ +EIM +GQ P+ + +EID + +R L+ VWR
Sbjct: 144 PLIELVTTPENSPEMIERAKEIMRGLGQFPLHVRKEIDAHIADR----FLEAVWR 194
>UniRef50_Q39LC4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Burkholderia sp. 383|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 333
Score = 61.3 bits (142), Expect = 3e-08
Identities = 40/139 (28%), Positives = 64/139 (46%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 303
E +GI+G+G IG SWA LF + G +V VYD + + +++ +LE GL R
Sbjct: 12 EVVGILGAGTIGASWAALFLAAGLEVDVYDPSPEGEAFVRDYVRHAWPSLERLGLARRGD 71
Query: 304 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 483
+F AV A FVQE VPE +++K +++ ++ +D I
Sbjct: 72 PGRLRFVATP-----EEAVARAQFVQESVPERIEIKHALYRRIEDHLDPRAIVCSSASGL 126
Query: 484 XXXXXXEGLKHKSQVIVSH 540
G K+ + I+ H
Sbjct: 127 LVKEMQAGWKNPGRFILGH 145
Score = 33.9 bits (74), Expect = 5.6
Identities = 23/88 (26%), Positives = 37/88 (42%)
Frame = +2
Query: 551 HLITYPLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWR 730
HLI PL E++ T+P V + + G+ + + +E+ G V NR+Q A+ E
Sbjct: 151 HLI--PLVELLGNEKTEPGVLELAEQFYAACGKITIRVNKEVPGHVANRLQAALWREAIH 208
Query: 731 LXXXXXXXXXXXXXXMSEGLGXEICIFG 814
L +S G G + G
Sbjct: 209 LVVEGVATVGDVDKAVSAGPGLRWSVMG 236
>UniRef50_Q7WLK3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=3; Bordetella|Rep: Putative 3-hydroxyacyl-CoA
dehydrogenase - Bordetella bronchiseptica (Alcaligenes
bronchisepticus)
Length = 313
Score = 60.9 bits (141), Expect = 4e-08
Identities = 30/85 (35%), Positives = 44/85 (51%)
Frame = +2
Query: 566 PLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLXXXX 745
P+ E+ + WT P+V M +GQ PV + +EI GFVLNR+Q A+L E++R+
Sbjct: 147 PVVEMAASAWTDPQVLAGAEAFMRSLGQHPVRIRKEIPGFVLNRLQGALLMEMFRVIADD 206
Query: 746 XXXXXXXXXXMSEGLGXEICIFGVL 820
+S+GLG G L
Sbjct: 207 VISPADADALISQGLGLRWATLGPL 231
Score = 59.7 bits (138), Expect = 1e-07
Identities = 40/138 (28%), Positives = 66/138 (47%), Gaps = 1/138 (0%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
+ ++G G+IG SWA++FA G +VT+ + A + + + E L G +
Sbjct: 4 VAVIGGGIIGASWAVVFARRGLEVTIVERDAACLAGLPARLAGMI---ERSASLLGAGEQ 60
Query: 310 SEQFQCIKGSTD-LATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 486
G+TD LA AV A +VQE V ENL LK+ +F LD++ + +
Sbjct: 61 PGDVAARIGATDALAAAVGRADYVQEAVSENLALKRTLFAELDALAPAHALLASSTSTYG 120
Query: 487 XXXXXEGLKHKSQVIVSH 540
E L +++ +V+H
Sbjct: 121 ASQFTEALAGRARCLVAH 138
>UniRef50_A3VGB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Rhodobacterales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Rhodobacterales bacterium HTCC2654
Length = 324
Score = 59.7 bits (138), Expect = 1e-07
Identities = 26/75 (34%), Positives = 39/75 (52%)
Frame = +2
Query: 566 PLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLXXXX 745
PL E+ P T PE ++ R E G +P+++ +EIDGF+LNR+QY ++ E L
Sbjct: 148 PLVELCATPLTAPETVERARRFYTEAGMEPITVNKEIDGFILNRLQYTLVAEAMHLVGEG 207
Query: 746 XXXXXXXXXXMSEGL 790
M+ GL
Sbjct: 208 YCSAADIDRVMTSGL 222
Score = 56.4 bits (130), Expect = 9e-07
Identities = 37/139 (26%), Positives = 65/139 (46%), Gaps = 1/139 (0%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQI-TDAIEDIKYQLHTLENDGLLRGEL 303
++ +G G +G WA +FA G++V +YD A I A+ I+ L L + + GE
Sbjct: 3 RVVCIGVGTVGCGWATVFARAGHEVVLYDADADAIAARALPRIEATLEQLGRE-MPTGET 61
Query: 304 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 483
A + + I+ + L A+ GA VQE V E+L +K+ +F + + D+ +
Sbjct: 62 PADIRAR-IRVAGSLEEALSGAEVVQESVREDLAIKRALFDEIGAAAPDDCLLLSSTSAL 120
Query: 484 XXXXXXEGLKHKSQVIVSH 540
+ H + +V H
Sbjct: 121 PGSQFLSDIPHPERALVGH 139
>UniRef50_Q8XI27 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase
NAD-dependent; n=9; Clostridiales|Rep:
Beta-hydroxybutyryl-CoA dehydrogenase NAD-dependent -
Clostridium perfringens
Length = 282
Score = 59.3 bits (137), Expect = 1e-07
Identities = 36/112 (32%), Positives = 58/112 (51%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 303
EKI ++G+G +G FA GY+V V D+ + + I I L L + G + E
Sbjct: 2 EKIFVIGAGTMGAGIVQAFAQKGYEVIVRDIKDEFVDRGIAGINKGLTKLVSKGKITEED 61
Query: 304 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
K + I G+TDL A + ++ V EN+++KK++F LD + + TI
Sbjct: 62 KEA-VLSKITGTTDLGLAADCDLVIEAAV-ENMEIKKQIFAELDKICKEETI 111
>UniRef50_Q73Q34 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
n=1; Treponema denticola|Rep: 3-hydroxyacyl-CoA
dehydrogenase, putative - Treponema denticola
Length = 309
Score = 59.3 bits (137), Expect = 1e-07
Identities = 39/146 (26%), Positives = 67/146 (45%)
Frame = +1
Query: 103 MASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLEND 282
M K K K+ +VG G +G + +FA G+ V + + + A++ IK L+ +
Sbjct: 1 MIEKGKKIKVAVVGDGTMGHGISEVFAKAGHTVQIIGLNDASLKSALDRIKLSLNEFVAE 60
Query: 283 GLLRGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIX 462
GL+ I STD+ A A+ + E +PEN+DLK + F L+ + +TI
Sbjct: 61 GLVSAS-DIDTIVGRISFSTDIQKAEDAAIVI-EALPENMDLKTETFGKLEKICPQDTIL 118
Query: 463 XXXXXXXXXXXXXEGLKHKSQVIVSH 540
+ +K + +VI +H
Sbjct: 119 ATASGHSVSEVIAQ-VKKRDRVIATH 143
Score = 56.4 bits (130), Expect = 9e-07
Identities = 26/56 (46%), Positives = 36/56 (64%)
Frame = +2
Query: 566 PLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRL 733
PL E+ AP T T E+++ IG++PV + +EIDGF+ NRIQ+A L E W L
Sbjct: 152 PLVEVCGAPETSKATIDTTCELLKGIGKKPVVIDKEIDGFIGNRIQFAALREAWAL 207
>UniRef50_Q2W2Y1 Cluster: Glyoxysomal fatty acid beta-oxidation
multifunctional protein MFP-a; n=3;
Magnetospirillum|Rep: Glyoxysomal fatty acid
beta-oxidation multifunctional protein MFP-a -
Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
Length = 703
Score = 59.3 bits (137), Expect = 1e-07
Identities = 37/111 (33%), Positives = 58/111 (52%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 306
K+GI+G+G +G AM FA++G VT+ DV + + + I+ + G L E +
Sbjct: 296 KVGIIGAGTMGGGIAMCFANIGIPVTIIDVSDENLQRGLGVIRKNYERSVSRGSLTQE-Q 354
Query: 307 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
+ + STD A A+K A E V E ++LKK +F LD+V+ I
Sbjct: 355 LESRMGLLSASTDYA-ALKDADLAIEAVFEKMELKKDIFAKLDAVLPAGAI 404
>UniRef50_Q24N80 Cluster: Putative uncharacterized protein; n=1;
Desulfitobacterium hafniense Y51|Rep: Putative
uncharacterized protein - Desulfitobacterium hafniense
(strain Y51)
Length = 313
Score = 59.3 bits (137), Expect = 1e-07
Identities = 37/115 (32%), Positives = 59/115 (51%)
Frame = +1
Query: 115 FKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLR 294
F++ K+ +VG+G++G A L+A G+QV +YD +Q+ A + I + L +GL
Sbjct: 2 FENWKLLVVGAGVMGSGIAQLYACKGFQVALYDKFPEQLDRAKQLIANNMENLIKEGLAT 61
Query: 295 GELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
E +A I T+L A V E V EN D+K++ F LD + + I
Sbjct: 62 QE-EAERTKTLISYETELEKCAPQADLVLESVFENADVKRETFAQLDKLCASDCI 115
Score = 41.1 bits (92), Expect = 0.037
Identities = 19/51 (37%), Positives = 29/51 (56%)
Frame = +2
Query: 569 LXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDE 721
L E+V P T E K + + ++G++P L + I GF++NRI AI E
Sbjct: 151 LVEVVMGPKTSDETLDKVKSFLIQVGKEPAVLKQYIPGFIVNRIATAITRE 201
>UniRef50_Q1GEJ8 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=17; Bacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase NAD-binding - Silicibacter sp. (strain
TM1040)
Length = 491
Score = 58.8 bits (136), Expect = 2e-07
Identities = 42/139 (30%), Positives = 64/139 (46%), Gaps = 4/139 (2%)
Frame = +1
Query: 136 IVGSGLIGRSWAMLFASVGYQVTVYDV---VAKQITDAIEDIKYQLHTLENDGLL-RGEL 303
I+G G+IG WA F G+ V V+D ++I D + + + L L N L G L
Sbjct: 7 IIGGGVIGGGWAARFLLNGWDVRVFDPDPEAERKIGDVLANARRSLPGLGNVALPPEGSL 66
Query: 304 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 483
E LA V+G +VQE VPE LDLK+KV+ L++ +
Sbjct: 67 SYHET---------LAETVQGVDWVQESVPERLDLKQKVYAELEAHAPGGAVIGSSTSGY 117
Query: 484 XXXXXXEGLKHKSQVIVSH 540
+G + +Q++V+H
Sbjct: 118 KPSQLQDGFTNAAQIVVAH 136
Score = 41.9 bits (94), Expect = 0.021
Identities = 22/55 (40%), Positives = 30/55 (54%)
Frame = +2
Query: 566 PLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWR 730
PL E+V PE+ K + I+ EIG P+ L +EID V +R L+ VWR
Sbjct: 145 PLVEVVTTDVNTPEMIAKAKAIITEIGMYPLHLKKEIDAHVADR----FLEAVWR 195
>UniRef50_A0GEI2 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Burkholderia|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Burkholderia phytofirmans
PsJN
Length = 317
Score = 58.4 bits (135), Expect = 2e-07
Identities = 34/90 (37%), Positives = 45/90 (50%)
Frame = +2
Query: 551 HLITYPLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWR 730
H+I PL E+VP T PEV ++T +M IG +PV L + I GFV NR+Q+A+L E
Sbjct: 159 HMI--PLVEVVPGTATAPEVTQQTAALMSAIGMEPVVLAKAIPGFVGNRLQFAMLREALH 216
Query: 731 LXXXXXXXXXXXXXXMSEGLGXEICIFGVL 820
+ M LG I G L
Sbjct: 217 IVRSGAATPDVVDRVMKASLGRRWGIVGPL 246
Score = 44.4 bits (100), Expect = 0.004
Identities = 34/137 (24%), Positives = 63/137 (45%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
IG+VG+GL+G A A G++ V+DV ++ + L L + G + K
Sbjct: 19 IGVVGTGLMGVGIATQSALHGHRTIVHDVDPARLASVAPKAQAVLDELIDAGRIDPAAKQ 78
Query: 310 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 489
+ + I+ +L + A FV E +PE L+LK +++ L ++ D+ I
Sbjct: 79 AALAR-IETHAEL-DVMASAQFVIEAIPEVLELKHRLYAALTQLLADDAILASNTSGFHP 136
Query: 490 XXXXEGLKHKSQVIVSH 540
L+ K + +++H
Sbjct: 137 DQLAAPLRAKDRFVIAH 153
>UniRef50_O30218 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 661
Score = 58.4 bits (135), Expect = 2e-07
Identities = 38/137 (27%), Positives = 61/137 (44%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
+ ++G+G +G + A + A G+ V + DV Q+ A+E I+ L G + +
Sbjct: 9 VAVIGAGSMGHAIAEVVAIHGFNVKLMDVSEDQLKRAMEKIEEGLRKSYERGYISED--P 66
Query: 310 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 489
+ + I+ + DL K A V E +PE DLKKKVF ++ D+TI
Sbjct: 67 EKVLKRIEATADLIEVAKDADLVIEAIPEIFDLKKKVFSEIEQYCPDHTIFATNTSSLSI 126
Query: 490 XXXXEGLKHKSQVIVSH 540
E K + I H
Sbjct: 127 TKLAEATKRPEKFIGMH 143
>UniRef50_Q2B4D1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Firmicutes|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Bacillus sp. NRRL B-14911
Length = 295
Score = 58.0 bits (134), Expect = 3e-07
Identities = 34/112 (30%), Positives = 60/112 (53%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 303
+ I +VG+G +G AML A G++ T++D+ K + A E ++ + G L E
Sbjct: 8 KNITVVGAGQMGHQIAMLCALGGFETTLHDMQEKALDQAQEKLRGIMDKWAAKGKLPSE- 66
Query: 304 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
+ F ++ ++D AVK A F+ E V E L++K++VF L+ + + I
Sbjct: 67 QIEAAFSRLRCTSDFGEAVKSADFIIEAVVEKLEVKREVFSMLEEMAPPHAI 118
Score = 35.5 bits (78), Expect = 1.8
Identities = 20/53 (37%), Positives = 28/53 (52%)
Frame = +2
Query: 575 EIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRL 733
E+V + T E A+ E+ I + V L +EI GFV NRI A+ E +L
Sbjct: 157 EVVMSSRTSEETAETAMEVCNAINRTAVLLKKEISGFVANRILGALQREAVQL 209
>UniRef50_A1IEK7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Candidatus
Desulfococcus oleovorans Hxd3
Length = 387
Score = 58.0 bits (134), Expect = 3e-07
Identities = 36/105 (34%), Positives = 53/105 (50%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 303
+KI ++GSG +G A + GY V + DV + + + ++ +K + L G L E
Sbjct: 7 KKIAVIGSGAMGHGIAQVCIMAGYTVVMVDVKQEFLDNGMKKVKESMDFLVGKGKLSAED 66
Query: 304 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDS 438
K Q + S D AV V E VPE +DLKKKVF ++ S
Sbjct: 67 KDRMMGQ-LSTSLDNKAAVADVQVVIEAVPEIMDLKKKVFADVSS 110
>UniRef50_Q0C7S2 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 589
Score = 57.6 bits (133), Expect = 4e-07
Identities = 37/116 (31%), Positives = 57/116 (49%), Gaps = 1/116 (0%)
Frame = +1
Query: 115 FKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIK-YQLHTLENDGLL 291
++ + I+G+G++GR A ++AS GY V V D +Q D + +K + + E+ G
Sbjct: 11 YRERPVAILGAGVLGRRIACIWASAGYDVQVRDPSPEQRADCVAYVKQHVVAYAEHTGAA 70
Query: 292 RGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
GE+ SE DL V A V E VPE + LK F+ LD + + I
Sbjct: 71 PGEVTTSE---------DLKNTVNNAWLVIEAVPEKIQLKIDTFEQLDKLAPTDCI 117
>UniRef50_A6C4K6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Planctomyces maris DSM 8797
Length = 311
Score = 57.2 bits (132), Expect = 5e-07
Identities = 38/141 (26%), Positives = 66/141 (46%), Gaps = 2/141 (1%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLL--RG 297
++IGI+G+GLIG SWA FA+ G +V ++DV A E L L + L+ +
Sbjct: 2 QEIGILGAGLIGASWATFFAAQGLRVRIFDVNNTVKQQAQELSVQNLQRLADLELISRKD 61
Query: 298 ELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXX 477
A E+ + +L T V+ +VQE V E+ ++K V+Q + + I
Sbjct: 62 AATAEEKLNVVDSLAELLTDVE---YVQESVIEDYEIKADVYQQFEQYAPEAAILGSSSS 118
Query: 478 XXXXXXXXEGLKHKSQVIVSH 540
++H + +++H
Sbjct: 119 GLLMTRMQTVMQHPGRALIAH 139
Score = 44.8 bits (101), Expect = 0.003
Identities = 22/57 (38%), Positives = 32/57 (56%)
Frame = +2
Query: 551 HLITYPLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDE 721
HLI PL E+VP T E + +E + +G+ PV L RE+ G + NR+ A+ E
Sbjct: 145 HLI--PLVELVPGEQTATETMETVKEFFQGLGKHPVILNREVPGHIANRLAAAVWRE 199
>UniRef50_A3YAS5 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Marinomonas sp. MED121|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Marinomonas sp. MED121
Length = 323
Score = 57.2 bits (132), Expect = 5e-07
Identities = 32/111 (28%), Positives = 57/111 (51%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 306
K+G++G+G+IG +WA+ + +G +V YD + + T+E GL G K
Sbjct: 12 KVGVIGTGVIGGAWALHYLRMGMEVVAYDPGPNSKEKLLTMVDNIWPTIEKLGLREGASK 71
Query: 307 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
++ + + LA V+ +QE PE LD K+ +F +LD +V + +
Sbjct: 72 --DKLRFVDSLDALANQVE---VIQESTPERLDAKRSLFADLDCIVPADVV 117
>UniRef50_Q9HRI4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7;
cellular organisms|Rep: 3-hydroxyacyl-CoA dehydrogenase
- Halobacterium salinarium (Halobacterium halobium)
Length = 286
Score = 57.2 bits (132), Expect = 5e-07
Identities = 35/120 (29%), Positives = 63/120 (52%), Gaps = 1/120 (0%)
Frame = +1
Query: 103 MASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQL-HTLEN 279
M S +E IG+VG+G +G A + A+ GY V + D+ + + + I+ L + N
Sbjct: 1 MRSLADTETIGVVGAGTMGAGIAQVAATAGYTVVMRDIEQEYVDAGFDSIESSLDRFVSN 60
Query: 280 DGLLRGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
D L E A I G+TDLA V ++ V E++++K+ +F++LD + ++ +
Sbjct: 61 DDL--SEADADAIVDRITGTTDLAELADCDVVIEAAV-EDMEIKQDIFRDLDDALPEDVV 117
>UniRef50_UPI00005102FD Cluster: COG1250: 3-hydroxyacyl-CoA
dehydrogenase; n=1; Brevibacterium linens BL2|Rep:
COG1250: 3-hydroxyacyl-CoA dehydrogenase -
Brevibacterium linens BL2
Length = 311
Score = 56.8 bits (131), Expect = 7e-07
Identities = 33/93 (35%), Positives = 46/93 (49%)
Frame = +2
Query: 551 HLITYPLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWR 730
HL+ PL E+VP P T EV K+ EI IG++P+ + E+ G V NR+Q A+ E +
Sbjct: 143 HLV--PLVELVPTPATPAEVVKRGLEIYRSIGKKPILVRAELPGHVTNRLQAALWQEAYS 200
Query: 731 LXXXXXXXXXXXXXXMSEGLGXEICIFGVLXKQ 829
L +S G G I G L +Q
Sbjct: 201 LVDRGMVSVEDIDTAISYGPGLRWAILGPLVQQ 233
Score = 52.0 bits (119), Expect = 2e-05
Identities = 41/140 (29%), Positives = 66/140 (47%), Gaps = 2/140 (1%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLH-TLENDGLLRGEL 303
K+ I+G+G+IG +WA F + G+ VT +D A ++ Q+ LE G G++
Sbjct: 6 KVAILGTGVIGAAWATGFLTAGHTVTAFD----PADGAEARLRSQVEGNLEVTG--EGDI 59
Query: 304 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNT-IXXXXXXX 480
++ + GS LA +V A FVQE PE LD+K+ + DS V + I
Sbjct: 60 TSAMERLHFAGS--LAESVGDADFVQENGPERLDIKQSMLAETDSAVPASAIIASSTSGF 117
Query: 481 XXXXXXXEGLKHKSQVIVSH 540
+ H +++V H
Sbjct: 118 APSELATKATNHPERIVVGH 137
>UniRef50_Q396V2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=9;
Bacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 317
Score = 56.8 bits (131), Expect = 7e-07
Identities = 35/107 (32%), Positives = 54/107 (50%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 303
+++ ++G+G+IG SWA LF + G V DV + + LE GL
Sbjct: 6 KRVAVIGTGVIGASWAALFLAKGLDVAATDVAPDAEARLRQYLDAAWPALEELGLAPAAS 65
Query: 304 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVV 444
+A F + DLA AV GA VQE PE +D K+ ++ LD+++
Sbjct: 66 RARLTF-----THDLAEAVAGAGLVQENGPERIDFKRTLYGQLDALL 107
Score = 39.5 bits (88), Expect = 0.11
Identities = 22/61 (36%), Positives = 32/61 (52%)
Frame = +2
Query: 551 HLITYPLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWR 730
HLI PL EIV T + +K +G++ + L +E+ G V NR+Q A+ EV
Sbjct: 146 HLI--PLVEIVSGAQTSEQTVEKVTAFYTSLGKRTIRLHKEVPGHVANRLQAALWREVVH 203
Query: 731 L 733
L
Sbjct: 204 L 204
>UniRef50_A2TU34 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
Flavobacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Dokdonia donghaensis MED134
Length = 394
Score = 56.0 bits (129), Expect = 1e-06
Identities = 38/115 (33%), Positives = 63/115 (54%), Gaps = 3/115 (2%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 303
+ IGI+G+G +G A + A+ G V ++DV + + A E ++ L L + +G +
Sbjct: 3 KNIGIIGAGTMGSGIAQVAATAGCAVKLFDVNQEALDKAKEALEKVLKRL----IEKGRI 58
Query: 304 KASEQFQCIKGSTDLATAVK---GAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
ASE+ + I+ + T +K A E + ENL++KKKVFQ L++ V D I
Sbjct: 59 DASEKDR-IQANITYVTTLKELANADLTIEAIVENLEVKKKVFQELETYVSDTAI 112
>UniRef50_A1FNB9 Cluster: 3-hydroxyacyl-CoA dehydrogenase precursor;
n=4; Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase
precursor - Pseudomonas putida W619
Length = 313
Score = 56.0 bits (129), Expect = 1e-06
Identities = 35/108 (32%), Positives = 58/108 (53%)
Frame = +1
Query: 136 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASE 315
++G+GL+G A +FA G++V++YD A + A + + H L+ G+ + A+
Sbjct: 9 VIGAGLMGHGIAQVFAQAGHKVSLYDPDAATLDLAPQRVA---HNLDQMGIASAPILAN- 64
Query: 316 QFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
I TDL AV A V E VPE L+LK+K+F ++ +T+
Sbjct: 65 ----IALFTDLREAVSNADIVIEAVPERLELKQKLFADIAGFAPPHTV 108
Score = 46.4 bits (105), Expect = 0.001
Identities = 26/104 (25%), Positives = 49/104 (47%)
Frame = +2
Query: 551 HLITYPLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWR 730
HL+ PL E+V T V + T E+++ +G+ PV + R++ GF+ NR+Q+A+ E
Sbjct: 143 HLV--PLVEVVRTEHTSLSVFESTFELLQSLGKSPVKVNRDVAGFIGNRLQHAMWREAIS 200
Query: 731 LXXXXXXXXXXXXXXMSEGLGXEICIFGVLXKQPI*MLKACKVI 862
L + + G + G + + L+ K++
Sbjct: 201 LVSQGVCDAETIDTVVKQSFGMRLPYLGPMENADLVGLQLTKLV 244
>UniRef50_Q39HR3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=24;
Burkholderia|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 305
Score = 55.2 bits (127), Expect = 2e-06
Identities = 39/106 (36%), Positives = 57/106 (53%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 306
+I IVG+G+IG SWA + + G+ DVVA TD +L E+ GE +
Sbjct: 5 RIAIVGAGVIGASWAAFYLTQGF-----DVVA---TDPAPQADTRLR--ESLAAFLGE-R 53
Query: 307 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVV 444
A+E + DL A+ G FVQE PE LDLK+ +++ +D V+
Sbjct: 54 AAELSARLSFDADLVRALDGVDFVQENGPERLDLKRALYRQMDDVL 99
Score = 42.3 bits (95), Expect = 0.016
Identities = 21/61 (34%), Positives = 35/61 (57%)
Frame = +2
Query: 551 HLITYPLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWR 730
HLI PL E+V T +V + ++ + +G+Q + L +E+ G V NR+ A+ EV+
Sbjct: 138 HLI--PLVELVGGDATSQDVTARVKDFYDALGKQTIVLNKEMTGHVANRLAAALFREVYH 195
Query: 731 L 733
L
Sbjct: 196 L 196
>UniRef50_A0PRD1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase FadB3;
n=1; Mycobacterium ulcerans Agy99|Rep:
3-hydroxybutyryl-CoA dehydrogenase FadB3 - Mycobacterium
ulcerans (strain Agy99)
Length = 294
Score = 55.2 bits (127), Expect = 2e-06
Identities = 38/141 (26%), Positives = 67/141 (47%)
Frame = +1
Query: 118 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG 297
+S + ++G+G +GR A++FAS G V +Y A+Q A + + L L D G
Sbjct: 13 RSRPVAVIGAGTLGRRIALMFASRGGTVRIYARRAEQRAQATQYVADNLPKLLQDRGF-G 71
Query: 298 ELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXX 477
E+ + C LATA++GA E VPE L++K ++ +D +TI
Sbjct: 72 EVGSVTATDC------LATALEGAWLAVESVPEKLEIKTALWGQIDQAAPPDTIFATNSS 125
Query: 478 XXXXXXXXEGLKHKSQVIVSH 540
+ ++ K+++ +H
Sbjct: 126 SFPSRLMADNVRDKTRLCNTH 146
>UniRef50_Q9UX37 Cluster: 3-hydroxyacyl-CoA-dehydrogenase; n=4;
Sulfolobaceae|Rep: 3-hydroxyacyl-CoA-dehydrogenase -
Sulfolobus solfataricus
Length = 324
Score = 55.2 bits (127), Expect = 2e-06
Identities = 30/111 (27%), Positives = 55/111 (49%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 306
K+ ++G+G+IG W L + GY+V +Y + + A+ + L L+N G++ E
Sbjct: 10 KVAVIGAGVIGVGWTTLLLAKGYKVNLYTEKKETLEKALAKVSAYLVNLKNLGMINEE-- 67
Query: 307 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
+ G T + A+ FV E + E+ KK +F+ LD+ + + I
Sbjct: 68 PESYITNLTGITKIDDAIHNVDFVIEAIIEDYTAKKNLFKLLDTQLPQDII 118
Score = 47.6 bits (108), Expect = 4e-04
Identities = 28/88 (31%), Positives = 40/88 (45%)
Frame = +2
Query: 551 HLITYPLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWR 730
HL+ PL EIVP T E TRE ME++ + V L +E+ GF+ NR+ +A+ E
Sbjct: 152 HLL--PLVEIVPGEKTSKETVDLTREFMEKLDRVVVLLRKEVPGFIGNRLAFALFREAVN 209
Query: 731 LXXXXXXXXXXXXXXMSEGLGXEICIFG 814
L M+ +G G
Sbjct: 210 LVDEGVATVEDIDKVMTAAIGLRWAFMG 237
>UniRef50_Q1DAC1 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Myxococcus xanthus DK 1622|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Myxococcus xanthus
(strain DK 1622)
Length = 321
Score = 54.4 bits (125), Expect = 4e-06
Identities = 32/110 (29%), Positives = 53/110 (48%)
Frame = +2
Query: 551 HLITYPLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWR 730
HLI PL +I+P T P+ + R +EE+G+ PV +R++ G V R+Q A++ E R
Sbjct: 150 HLI--PLVDIIPGEKTSPDAVETVRRFIEELGKSPVVFSRDVPGSVGPRLQQALIGEAIR 207
Query: 731 LXXXXXXXXXXXXXXMSEGLGXEICIFGVLXKQPI*MLKACKVILIXTER 880
L +++G+G + GV + + L +L T R
Sbjct: 208 LVHEGVATPEMVDRVLTQGVGRRLGASGVFDRLDLVGLDFMTALLRGTGR 257
Score = 52.4 bits (120), Expect = 2e-05
Identities = 36/112 (32%), Positives = 57/112 (50%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 303
++IG+VG G +G A+ A G QV +Y+ A A ++ L GLL E
Sbjct: 7 KRIGMVGGGAMGCGIALELAIAGRQVVLYNTRADSSERARAKLERDASLLVETGLLAPE- 65
Query: 304 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
+A I+ +T LA A V E +PE+L LK+++F+ LD + +T+
Sbjct: 66 QAPAAIGRIRRTTVLAEAAVEQDLVIESIPEDLALKQQLFRELDQLAAPDTL 117
>UniRef50_Q5V0V6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Halobacteriaceae|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Haloarcula marismortui (Halobacterium marismortui)
Length = 654
Score = 54.4 bits (125), Expect = 4e-06
Identities = 30/103 (29%), Positives = 54/103 (52%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
+ ++G+G +G A + A GY V + D+ A + D ++I++ L L G L +
Sbjct: 11 VAVLGAGTMGHGIAEVAAIAGYDVVLRDIDAAIVEDGYDEIEWSLEKLAEKGRL--DEDP 68
Query: 310 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDS 438
+ + +TDL AV A V E PE L +K+ +F+++D+
Sbjct: 69 DDVAARVATTTDLEAAVSDADLVIEAGPEQLSVKQDIFESVDA 111
>UniRef50_UPI000050F939 Cluster: COG1250: 3-hydroxyacyl-CoA
dehydrogenase; n=1; Brevibacterium linens BL2|Rep:
COG1250: 3-hydroxyacyl-CoA dehydrogenase -
Brevibacterium linens BL2
Length = 314
Score = 54.0 bits (124), Expect = 5e-06
Identities = 27/76 (35%), Positives = 38/76 (50%)
Frame = +2
Query: 566 PLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLXXXX 745
PL E+VPAP T + ++ E G++PV+L RE+ GFV NR+Q A++ E L
Sbjct: 146 PLVEVVPAPATSSDTVERALEFYRSCGREPVALNREVRGFVGNRLQNALMKEAISLVENG 205
Query: 746 XXXXXXXXXXMSEGLG 793
M LG
Sbjct: 206 VISAPDLDSVMKNSLG 221
Score = 53.2 bits (122), Expect = 9e-06
Identities = 35/110 (31%), Positives = 58/110 (52%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
+ ++G+G IGRS+A LFA GY V V+D + + + +++ ++ D ++ A
Sbjct: 5 VAVIGAGTIGRSFAWLFARSGYPVQVFD-PRPDLAEVVTELQAEVSA---DAAAH-DMLA 59
Query: 310 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
SE I + + TAV GA FVQE PE+ K K+F + + + I
Sbjct: 60 SE-LGTISLAESVETAVAGASFVQESGPEDPQAKPKLFAQIAAAAPKDAI 108
>UniRef50_Q7WCB1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
Bordetella|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Bordetella parapertussis
Length = 354
Score = 54.0 bits (124), Expect = 5e-06
Identities = 37/112 (33%), Positives = 55/112 (49%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 303
+ + +VG+G +G A LFAS G+ V + D +A +T A + I+ QL D +
Sbjct: 50 QNLAVVGAGAMGSGIAALFASKGFDVVLIDPMAGALTRAAQVIERQLGVYAPDAI----- 104
Query: 304 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
+ Q I+ L A A V E VPE L LK+ +F LD++ D I
Sbjct: 105 --APAMQRIRMDAGLEAAC-SAQLVIEAVPEKLALKRDIFARLDTLCDPQAI 153
Score = 39.1 bits (87), Expect = 0.15
Identities = 22/88 (25%), Positives = 40/88 (45%)
Frame = +2
Query: 566 PLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLXXXX 745
PL E+V T + + ++ G++PV + ++I GF+ NRIQ+A+ E L
Sbjct: 189 PLVEVVRNDDTSEQTVARVMGMLRAGGKRPVLVRKDIPGFIANRIQHALAREAISLLEKG 248
Query: 746 XXXXXXXXXXMSEGLGXEICIFGVLXKQ 829
+ LG + + G L ++
Sbjct: 249 VASAEDIDEVVKWSLGIRLALSGPLEQR 276
>UniRef50_Q11E57 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=1; Mesorhizobium sp. BNC1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Mesorhizobium sp. (strain BNC1)
Length = 485
Score = 54.0 bits (124), Expect = 5e-06
Identities = 35/137 (25%), Positives = 65/137 (47%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
IG++G+G +G A + A+ G++V ++DV + +E +L TL G + + +A
Sbjct: 11 IGVIGAGTMGAGIAQVAAAAGHKVLLFDVASGAAASGLERTAKELATLVKRGKME-QKRA 69
Query: 310 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 489
E I + L A+ V E + E LD+K+KVF L++++ ++ I
Sbjct: 70 EEIIGRITIAEKLEDLAPAALTV-EAIVERLDVKQKVFAQLEAILAEDAILATNTSSISI 128
Query: 490 XXXXEGLKHKSQVIVSH 540
LK +++ H
Sbjct: 129 TAIGAALKRPERLVGMH 145
Score = 33.1 bits (72), Expect = 9.8
Identities = 24/84 (28%), Positives = 35/84 (41%)
Frame = +2
Query: 569 LXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLXXXXX 748
L E+V T PEVA+ T G+ V + + GF++NR+ A E RL
Sbjct: 155 LVEVVSGLATSPEVAQITHATARAWGKTAVHV-KSTPGFIVNRVARAFYGEPLRLAEEGM 213
Query: 749 XXXXXXXXXMSEGLGXEICIFGVL 820
M EG G + F ++
Sbjct: 214 ADIATLDALMREGGGFRMGAFQLM 237
>UniRef50_Q5UWD9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyacyl-CoA dehydrogenase
- Haloarcula marismortui (Halobacterium marismortui)
Length = 295
Score = 54.0 bits (124), Expect = 5e-06
Identities = 35/113 (30%), Positives = 57/113 (50%), Gaps = 3/113 (2%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG---E 300
+ I+G+G +G A + A G+ V++ D+ A + D + I+ L +G+ R E
Sbjct: 4 VAILGAGTMGHGIAQVSAMAGHDVSLRDIEADIVDDGLTAIESNLE----EGIAREKVTE 59
Query: 301 LKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
A +KG+T L AV GA V E VPE + +K + ++S VD T+
Sbjct: 60 STAEATIDRLKGTTSLEEAVTGADLVVEAVPEEMAIKHETLTAVESHVDPATL 112
>UniRef50_A0RUN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase; n=4; Crenarchaeota|Rep: 3-hydroxyacyl-CoA
dehydrogenase/enoyl-CoA hydratase - Cenarchaeum
symbiosum
Length = 365
Score = 54.0 bits (124), Expect = 5e-06
Identities = 31/99 (31%), Positives = 53/99 (53%)
Frame = +1
Query: 154 IGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASEQFQCIK 333
+G A + A+ GY+V + D+ + + A+E I++ L + + G + E K I+
Sbjct: 1 MGHGIAQVSAASGYEVVLRDIEQRFLDSAMEKIRWSLDKMASKGRITAEEKDGI-LNRIR 59
Query: 334 GSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDD 450
L A++GA V E VPE +DLK+KV+ LD+ +
Sbjct: 60 PVVALGEALEGADLVIEAVPEVMDLKRKVYAELDAAAPE 98
Score = 41.5 bits (93), Expect = 0.028
Identities = 21/81 (25%), Positives = 37/81 (45%)
Frame = +2
Query: 569 LXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLXXXXX 748
L E++P T E + T E +E +G+Q V +++ GF++NR+ ++ E
Sbjct: 138 LVEVIPGEGTSDETTRMTLEYVESLGKQAVLCRKDVPGFIVNRLFIPMVHEACHAMDRTG 197
Query: 749 XXXXXXXXXMSEGLGXEICIF 811
+ GLG + IF
Sbjct: 198 ASMEQIDSAVKFGLGFPMGIF 218
>UniRef50_P76083 Cluster: Probable 3-hydroxybutyryl-CoA
dehydrogenase; n=8; Enterobacteriaceae|Rep: Probable
3-hydroxybutyryl-CoA dehydrogenase - Escherichia coli
(strain K12)
Length = 475
Score = 54.0 bits (124), Expect = 5e-06
Identities = 35/112 (31%), Positives = 58/112 (51%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 303
+ + ++GSG +G A + AS G+QV +YD+ A+ +T AI+ I +L++ G L E
Sbjct: 6 QTVAVIGSGTMGAGIAEVAASHGHQVLLYDISAEALTRAIDGIHARLNSRVTRGKLTAE- 64
Query: 304 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
+ + TD+ A+ A V E E L++KK +F L V T+
Sbjct: 65 TCERTLKRLIPVTDI-HALAAADLVIEAASERLEVKKALFAQLAEVCPPQTL 115
>UniRef50_Q5P039 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum
(strain EbN1))
Length = 443
Score = 53.6 bits (123), Expect = 6e-06
Identities = 34/111 (30%), Positives = 58/111 (52%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 306
++G++G+G +G AM FA+VG VTV D + +E ++ G L
Sbjct: 43 RVGVIGAGTMGGGIAMSFANVGIPVTVCDTDGAALERGLERVRRNYEFSVARGRLDAATM 102
Query: 307 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
A+ + I+ + DL +K A V E V E++ LK+ +F+ LD++V + I
Sbjct: 103 AA-RLALIRAAVDLQD-LKDADLVIEAVFEDMALKQDIFRKLDAIVHPDAI 151
>UniRef50_A5D5N2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Pelotomaculum thermopropionicum SI|Rep:
3-hydroxyacyl-CoA dehydrogenase - Pelotomaculum
thermopropionicum SI
Length = 319
Score = 53.6 bits (123), Expect = 6e-06
Identities = 34/110 (30%), Positives = 51/110 (46%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
+ I+G+G +G S A G V + DV A + A I+ L + G +G
Sbjct: 7 LAIIGAGTMGHSIAAAALQHGVSVRLIDVSAPALETARRKIQSYLASAAGKGGGKGGAVP 66
Query: 310 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
++ ++A V GA V E VPE LDLKK++F LD + + I
Sbjct: 67 GHLAGVLETCMEMAAGVTGADMVIEAVPEKLDLKKEIFAQLDKLCPPSVI 116
Score = 50.0 bits (114), Expect = 8e-05
Identities = 22/52 (42%), Positives = 36/52 (69%)
Frame = +2
Query: 566 PLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDE 721
PL E+V + +T P+VA T ++ IG++PV + ++I GF+ NR+Q+AI E
Sbjct: 152 PLVEVVCSDYTSPDVAGDTVAFLQSIGRKPVLVKKDIPGFIGNRLQHAIARE 203
>UniRef50_A3STE1 Cluster: Putative hydroxlacyl-CoA dehydrogenase;
n=3; Rhodobacteraceae|Rep: Putative hydroxlacyl-CoA
dehydrogenase - Sulfitobacter sp. NAS-14.1
Length = 309
Score = 53.6 bits (123), Expect = 6e-06
Identities = 35/140 (25%), Positives = 59/140 (42%), Gaps = 3/140 (2%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDV---VAKQITDAIEDIKYQLHTLENDGLLRGE 300
+ ++G GLIG SWA LF G+ V +D + QL + +G
Sbjct: 7 VAVIGCGLIGASWAALFQHAGHTVRAWDPDTGARDGFAARVAGPLAQLQEISAGAAPQGA 66
Query: 301 LKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 480
L E Q A++ V +QE PEN+ LK +++ ++S+V + I
Sbjct: 67 LSTHESLQ---------DALQDVVLIQENAPENVPLKHQLYAQIESIVAPDVIIASSTSA 117
Query: 481 XXXXXXXEGLKHKSQVIVSH 540
G++H ++I +H
Sbjct: 118 HPWSDLVPGMQHPDRLITAH 137
>UniRef50_A0LSM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5;
Actinomycetales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 301
Score = 53.6 bits (123), Expect = 6e-06
Identities = 40/138 (28%), Positives = 63/138 (45%), Gaps = 1/138 (0%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDG-LLRGELK 306
+G+VGSGL+G A + A GY V ++D+ + A+ I LH L G L +++
Sbjct: 10 VGVVGSGLMGSGIAQVAAVAGYAVRLHDIEESALHRALTTIDESLHRLARKGKLSTSDVE 69
Query: 307 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 486
A++ I + LA V V E V E LD+K+ VF L ++V N +
Sbjct: 70 AAK--ARITTTRRLADLADSDVVV-EAVYEELDVKRVVFAELAAIVRPNVLLASNTTAIP 126
Query: 487 XXXXXEGLKHKSQVIVSH 540
G+ +V+ H
Sbjct: 127 ITHIASGVSGPQRVVGMH 144
Score = 35.1 bits (77), Expect = 2.4
Identities = 17/55 (30%), Positives = 29/55 (52%)
Frame = +2
Query: 569 LXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRL 733
L EIV T + + R E +G+ + + R++ GFV +R+ A ++E RL
Sbjct: 154 LCEIVRGLQTDDDTVARARRFAESLGKTCIVVNRDVAGFVTSRLLVAFVNEALRL 208
>UniRef50_A1CC71 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
n=2; Aspergillus|Rep: 3-hydroxyacyl-CoA dehydrogenase,
putative - Aspergillus clavatus
Length = 307
Score = 53.2 bits (122), Expect = 9e-06
Identities = 38/139 (27%), Positives = 66/139 (47%), Gaps = 2/139 (1%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDG--LLRGEL 303
+ ++G G++GR M++A+ G+ V +Y+ K A+ +KY L LL G+
Sbjct: 16 VAVIGGGVLGRRLCMMWAAAGHTVQLYE---KSPEVAVAALKYIHEALPQQASKLLLGK- 71
Query: 304 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 483
KA + ++ L TAV+ A V E +PE L LK ++F LD + + I
Sbjct: 72 KAGHGIGHVSPASSLETAVQNAWMVIEAIPELLPLKIELFGQLDQLAPADCILATNSSSY 131
Query: 484 XXXXXXEGLKHKSQVIVSH 540
E + +++V +H
Sbjct: 132 KSREMLEKVARRARVCNAH 150
>UniRef50_Q16836 Cluster: Hydroxyacyl-coenzyme A dehydrogenase,
mitochondrial precursor; n=40; Eukaryota|Rep:
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
precursor - Homo sapiens (Human)
Length = 314
Score = 53.2 bits (122), Expect = 9e-06
Identities = 38/140 (27%), Positives = 65/140 (46%), Gaps = 5/140 (3%)
Frame = +1
Query: 55 RFTRGLSCGTVASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQIT 234
+F R +S + AS A K + + ++G GL+G A + A+ G+ V + D +
Sbjct: 7 QFMRSVSSSSTASA--SAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILA 64
Query: 235 DAIEDIKYQLHTLENDGLLRGELKASEQF-----QCIKGSTDLATAVKGAVFVQECVPEN 399
+ + I+ L + KA ++F I STD A+ V V E + EN
Sbjct: 65 KSKKGIEESLRKVAKKKFAENP-KAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVEN 123
Query: 400 LDLKKKVFQNLDSVVDDNTI 459
L +K ++F+ LD ++TI
Sbjct: 124 LKVKNELFKRLDKFAAEHTI 143
>UniRef50_Q988C8 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1;
Mesorhizobium loti|Rep: 3-hydroxybutyryl-coA
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 309
Score = 52.8 bits (121), Expect = 1e-05
Identities = 36/110 (32%), Positives = 51/110 (46%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
I I+G G +G A A G QV YDV AIE + L E G
Sbjct: 5 IAIIGLGTMGPGMAARLARGGLQVVAYDVAPA----AIERARSMLSVAETVLDALGIALP 60
Query: 310 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
S ++ + D+ AV GA V E VPEN+ +K V++ +D ++ +TI
Sbjct: 61 SAGVGTVRFTDDIGDAVSGADLVIENVPENISIKADVYRTIDGLIGQDTI 110
Score = 50.4 bits (115), Expect = 6e-05
Identities = 26/88 (29%), Positives = 44/88 (50%)
Frame = +2
Query: 551 HLITYPLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWR 730
H+I P+ E++ T P+ R+++ IG PV + +++ GFV NR+ YA+L E
Sbjct: 143 HII--PMIEVIAGEKTAPQTVATIRDLIRSIGLLPVVVKKDVPGFVENRVLYALLREAVD 200
Query: 731 LXXXXXXXXXXXXXXMSEGLGXEICIFG 814
L +S G+G +I + G
Sbjct: 201 LVERGVIDPEDLDTCVSWGIGYKIAVIG 228
>UniRef50_Q67SZ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Symbiobacterium thermophilum
Length = 517
Score = 52.8 bits (121), Expect = 1e-05
Identities = 31/111 (27%), Positives = 59/111 (53%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 306
++G+VG+G +G A + A G+ V +YDV + + A+ ++ L G + + +
Sbjct: 3 RLGVVGAGTMGAGIAQVAAQSGFDVLLYDVDPEALARALGRVESDLQRQAARGRI-PDAQ 61
Query: 307 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
+E I +T L A FV E PE+L+LK+++F+ LD + ++ +
Sbjct: 62 VAEVLGRITTTTSLGD-FAAADFVIEAAPEDLELKRRLFERLDRLCREDVV 111
>UniRef50_Q397D0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=31;
Proteobacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 518
Score = 52.8 bits (121), Expect = 1e-05
Identities = 32/107 (29%), Positives = 53/107 (49%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
+G++G+G +G A + A+ G+ V +YD+ A+ I+ Q L G L +A
Sbjct: 20 VGVIGAGAMGAGIAQVAAAAGHTVLLYDLNEAACDKALAGIRAQFARLAEKGRLE-PAQA 78
Query: 310 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDD 450
I+ +LA GA + E E LD+K+++F L+ VDD
Sbjct: 79 DAAGARIRAVRELAD-FAGAALIVEAAAERLDVKREIFATLERHVDD 124
>UniRef50_A3M445 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Acinetobacter baumannii ATCC 17978|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Acinetobacter
baumannii (strain ATCC 17978 / NCDC KC 755)
Length = 233
Score = 52.8 bits (121), Expect = 1e-05
Identities = 28/88 (31%), Positives = 43/88 (48%)
Frame = +2
Query: 551 HLITYPLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWR 730
HL+ PL EIV T P++ KK E + +G+ P+ L +E+ G V NR+Q A+ E +
Sbjct: 67 HLL--PLVEIVGGKLTDPQILKKASEFYQSLGKHPIVLNKEVKGHVANRLQAALWREAFS 124
Query: 731 LXXXXXXXXXXXXXXMSEGLGXEICIFG 814
L ++ G G +FG
Sbjct: 125 LVKEGVCSAEDVDIAITSGPGLRWALFG 152
Score = 33.1 bits (72), Expect = 9.8
Identities = 14/56 (25%), Positives = 25/56 (44%)
Frame = +1
Query: 373 FVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXXEGLKHKSQVIVSH 540
F+QE PE LDLK+ ++Q + S + T+ + H ++ + H
Sbjct: 6 FIQENAPERLDLKQNLYQEITSYCPEKTLIASSSSGLKVSDFQKDATHPERIFLGH 61
>UniRef50_O29815 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 304
Score = 52.8 bits (121), Expect = 1e-05
Identities = 38/111 (34%), Positives = 57/111 (51%), Gaps = 3/111 (2%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIK---YQLHTLENDGLLR 294
EKIG+VG GL+G FA G +V DV +++ +E IK + L L G +
Sbjct: 3 EKIGVVGFGLMGTQITQFFAQQGLEVVAIDVSEERLRKGMEAIKAGRFGLQRLVEKGKIT 62
Query: 295 GELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVD 447
E + + I ST +A+K V E V E+++LK KV + +D+V D
Sbjct: 63 EE-EMNAVLSRISTSTS-HSALKDCDLVIEAVFEDVNLKLKVLREIDAVTD 111
>UniRef50_Q9KBD3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=8;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Bacillus halodurans
Length = 287
Score = 52.4 bits (120), Expect = 2e-05
Identities = 37/113 (32%), Positives = 61/113 (53%), Gaps = 3/113 (2%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQ-LHTLENDGLLRGELK 306
+G+VG+G +G A L A G QV + D+ Q+ DI +Q ++T + +G++
Sbjct: 6 VGVVGAGTMGSGIANLAAMSGLQVVLLDLDDNQL-----DIAWQKINTFMEKSVAKGKMS 60
Query: 307 ASEQFQCIKG--STDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
+E+ + ST + A V E V ENLD+KK+VF LD+ + ++TI
Sbjct: 61 EAEKEAALGRIKSTTTYEELAEADLVIEAVIENLDVKKEVFHTLDTCLANDTI 113
>UniRef50_Q891F6 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxybutyryl-coA dehydrogenase -
Clostridium tetani
Length = 282
Score = 52.4 bits (120), Expect = 2e-05
Identities = 32/112 (28%), Positives = 59/112 (52%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 303
+KI ++G+G +G A FA+ GY+V + D+ + + I+ I+ L L + G + E
Sbjct: 2 KKICVLGAGTMGAGIAQAFAAKGYEVVLRDIKDEFVERGIKGIEKGLSKLVSKGRMAQE- 60
Query: 304 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
I+G+ DL A + V+ + EN+++K+++F LD + TI
Sbjct: 61 DMDSILGRIEGTVDLNKAADCDLVVEAAI-ENMEIKREIFAELDRICKPETI 111
>UniRef50_A1I839 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Candidatus
Desulfococcus oleovorans Hxd3
Length = 289
Score = 52.4 bits (120), Expect = 2e-05
Identities = 37/113 (32%), Positives = 58/113 (51%), Gaps = 1/113 (0%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 303
+++ I G+G +GRS + A G +V +YDV + A + ++ + G L E
Sbjct: 7 KRVLIAGAGTMGRSIGLSCAVRGCEVILYDVKEDALEAARRAMAVKIDKMVPAGALTPE- 65
Query: 304 KASEQFQC-IKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
A+E + I +TDLA A A V E VPE+ D+K + F+ L V + TI
Sbjct: 66 -AAESIKANITTTTDLAAAGADADLVSESVPEDPDIKGEFFEKLHGVCPERTI 117
>UniRef50_Q12D24 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=5; Burkholderiales|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 511
Score = 52.0 bits (119), Expect = 2e-05
Identities = 38/153 (24%), Positives = 69/153 (45%)
Frame = +1
Query: 82 TVASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQ 261
T+ STV +K + +VG+G++G A + A G+ V +YD +A +
Sbjct: 2 TMNSTV---NKLDEAPLLVVGAGVMGVGIAQVAAQAGHAVMLYDAREGAAAEAKTKLAKS 58
Query: 262 LHTLENDGLLRGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSV 441
L L G L + S+ I+ LA A + + E + E LD+K+ +FQ L+++
Sbjct: 59 LDALVAKGKLTAQ-GVSQTLSRIEAIASLAAAAPARLVI-EAIVEKLDVKRGLFQQLEAI 116
Query: 442 VDDNTIXXXXXXXXXXXXXXEGLKHKSQVIVSH 540
V + + GL+H ++++ H
Sbjct: 117 VAADCVLATNTSSISVTAIANGLQHPARLVGMH 149
>UniRef50_A2QXC7 Cluster: Contig An11c0270, complete genome.
precursor; n=6; Pezizomycotina|Rep: Contig An11c0270,
complete genome. precursor - Aspergillus niger
Length = 599
Score = 52.0 bits (119), Expect = 2e-05
Identities = 32/107 (29%), Positives = 52/107 (48%)
Frame = +1
Query: 121 SEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGE 300
S + ++G+G++GR A +FA+ GY V +YD A++ + L T
Sbjct: 12 SRPLALLGAGVLGRRIACVFAAAGYNVNLYDPSLSAQQAALDYVTQNLKTYSKFS----- 66
Query: 301 LKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSV 441
K + +F + +DL + V A V E VPE+L +K V LD +
Sbjct: 67 -KGNRRFGHCRAFSDLESTVSDAWLVIEAVPEHLQMKIDVMGELDKL 112
Score = 37.9 bits (84), Expect = 0.35
Identities = 19/43 (44%), Positives = 25/43 (58%)
Frame = +2
Query: 596 TKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEV 724
T PEV ++E++G PV+ RE GFV NR+ AI EV
Sbjct: 165 TWPEVFPFLTRVLEDVGMVPVTARRESTGFVFNRLWAAIKREV 207
>UniRef50_Q8G825 Cluster: Possible butyryl-CoA dehydrogenase; n=2;
Bifidobacterium longum|Rep: Possible butyryl-CoA
dehydrogenase - Bifidobacterium longum
Length = 319
Score = 51.6 bits (118), Expect = 3e-05
Identities = 35/137 (25%), Positives = 55/137 (40%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
I VG+G +G + + FA GY V + + A++ I+ GLL+
Sbjct: 11 IANVGTGTMGHAITLQFALAGYPVHLVGRSEASLEKAMKAIRSDAEDFAEAGLLKAGDTV 70
Query: 310 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 489
I G D A+ V FV E V ENLD+KK V+ ++ + I
Sbjct: 71 DTVLARITGYADYASGVADVDFVIESVAENLDVKKSVWTEVEHAAPKDAILSTNTSGLSP 130
Query: 490 XXXXEGLKHKSQVIVSH 540
+ H + +V+H
Sbjct: 131 TALQSVMGHPERFVVAH 147
Score = 49.6 bits (113), Expect = 1e-04
Identities = 23/54 (42%), Positives = 35/54 (64%)
Frame = +2
Query: 566 PLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVW 727
PL E+VP T P+V T ++M +IG++P + +E GFV NR+Q A+L E +
Sbjct: 156 PLVEVVPGEKTDPKVVDITFDLMAKIGKKPAKIKKESLGFVGNRLQLAVLREAF 209
>UniRef50_UPI000023E2B1 Cluster: hypothetical protein FG00090.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG00090.1 - Gibberella zeae PH-1
Length = 320
Score = 51.2 bits (117), Expect = 3e-05
Identities = 28/88 (31%), Positives = 44/88 (50%)
Frame = +2
Query: 551 HLITYPLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWR 730
HLI PL E+VP P T +V + +G++P+ L +E+ GFV NR+Q AI +E +
Sbjct: 145 HLI--PLVEVVPHPGTSSDVVSSALAFYKSLGKKPILLHQEVPGFVSNRLQAAINNEAYS 202
Query: 731 LXXXXXXXXXXXXXXMSEGLGXEICIFG 814
L +++G G + G
Sbjct: 203 LISRGIVSAKDLDMAVTQGPGLRWALTG 230
Score = 45.2 bits (102), Expect = 0.002
Identities = 31/103 (30%), Positives = 50/103 (48%), Gaps = 1/103 (0%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL-K 306
+ IVG G+IG WA+LF S G +V +++ A E +K L + RG K
Sbjct: 8 VAIVGCGVIGMGWAVLFMSCGLKV----IISDPADGAHESLKRYLEQARSFFEERGNFDK 63
Query: 307 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLD 435
S ++ + D+ + FVQE PE ++ K+ + + LD
Sbjct: 64 LSSNYEFV---DDILPLLPEVDFVQENGPERVEFKQSLMEKLD 103
>UniRef50_A1SSP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Psychromonas ingrahamii 37|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Psychromonas ingrahamii (strain 37)
Length = 511
Score = 51.2 bits (117), Expect = 3e-05
Identities = 31/116 (26%), Positives = 62/116 (53%)
Frame = +1
Query: 112 KFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLL 291
K + + ++G+G +G A + A GYQV ++D+ + +A E+I+ QL G +
Sbjct: 3 KLLFKTVAVIGAGAMGAGIAQVAAQSGYQVYLFDLAKGKAEEAKENIEKQLERRVKKGRM 62
Query: 292 RGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
+ S + I S++L + + A V E + ENL++K+ +F+ L+++ + I
Sbjct: 63 EQQTLESTLLR-IHCSSEL-SEIASANLVIEAIVENLEIKQGLFKELETICSADCI 116
>UniRef50_Q5V357 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
Halobacteriaceae|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Haloarcula marismortui (Halobacterium marismortui)
Length = 669
Score = 51.2 bits (117), Expect = 3e-05
Identities = 31/113 (27%), Positives = 57/113 (50%), Gaps = 1/113 (0%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTL-ENDGLLRGE 300
+ I ++G+G +G + A GY V + D+ + + D ++I++ L+ L E D L + E
Sbjct: 22 DTIAVLGAGNMGHGITEVAALAGYDVRMRDIKDEFVEDGYDNIEWSLNKLAERDQLTQEE 81
Query: 301 LKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
A+ + D+ AV V E VPE +++KK V+ ++ +N I
Sbjct: 82 ADAA--LDRVTPLVDVEEAVSDVDVVIEAVPEKMEIKKDVYTEVEEHAPENAI 132
>UniRef50_Q0SEM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 286
Score = 50.8 bits (116), Expect = 5e-05
Identities = 34/104 (32%), Positives = 52/104 (50%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
+G+VG+G +G A A G+ V V D + + A ++ L G G K
Sbjct: 9 VGVVGAGTMGAGVAECLAQAGHDVIVVDPDPQAVDQARSRMRDSLRLAILLGRAGGP-KP 67
Query: 310 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSV 441
+E + + ++ T ++ A V ECVPE +DLK+KVF LD V
Sbjct: 68 AEVTARVHWTGEM-TDLRDAAVVIECVPERIDLKEKVFAELDRV 110
>UniRef50_A0VLT7 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Dinoroseobacter shibae DFL 12|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Dinoroseobacter shibae DFL 12
Length = 391
Score = 50.4 bits (115), Expect = 6e-05
Identities = 39/104 (37%), Positives = 55/104 (52%), Gaps = 3/104 (2%)
Frame = +1
Query: 136 IVGSGLIGRSWAMLFASVGYQVTVYDV---VAKQITDAIEDIKYQLHTLENDGLLRGELK 306
I+GSG IG WA F G+ V V+D ++T IE + L L D L +
Sbjct: 7 IIGSGRIGSGWAARFLLFGWHVRVFDADPGAQARLTQVIEAARTSLLGLY-DTPLPPPGR 65
Query: 307 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDS 438
S+ GS +A AV GAV+VQE VPE+L LK++V + + +
Sbjct: 66 LSQH-----GS--IAEAVAGAVWVQESVPEDLSLKREVVREVQA 102
>UniRef50_Q2J5F5 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=3; Actinomycetales|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Frankia sp. (strain CcI3)
Length = 323
Score = 50.0 bits (114), Expect = 8e-05
Identities = 35/138 (25%), Positives = 57/138 (41%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 306
++ ++G+G IG W LF + GY+V V IE + + L GL
Sbjct: 11 RVAVIGAGSIGLGWITLFLAHGYRVRV-----NSTRSNIETVIHDALRLFTPGLPGASRD 65
Query: 307 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 486
++ ++ DL AV VQE PENL++K+ +F L+ T+
Sbjct: 66 PADLAGRLEIEPDLERAVADVAVVQENTPENLEIKQDLFARLEKHAAAGTLLLSSTSTML 125
Query: 487 XXXXXEGLKHKSQVIVSH 540
+ + S +IV H
Sbjct: 126 PADLGARMDNPSHLIVGH 143
Score = 39.9 bits (89), Expect = 0.086
Identities = 19/52 (36%), Positives = 26/52 (50%)
Frame = +2
Query: 566 PLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDE 721
PL E+V + P+ E +G+ PV L R I F NR+Q A+L E
Sbjct: 152 PLVEVVGDTTSDPDAVSAAAEFYRSVGKTPVVLRRPIAAFAANRLQSALLQE 203
>UniRef50_O69856 Cluster: Fatty acid oxidation complex
alpha-subunit; n=6; Actinobacteria (class)|Rep: Fatty
acid oxidation complex alpha-subunit - Streptomyces
coelicolor
Length = 709
Score = 50.0 bits (114), Expect = 8e-05
Identities = 35/139 (25%), Positives = 63/139 (45%), Gaps = 1/139 (0%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLF-ASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 303
K+G+VG+GL+ A+LF + V + D+ +++ + + ++ L G + +
Sbjct: 340 KVGVVGAGLMASQLALLFLRRLEVPVVLTDIDQERVDKGVGYVHAEIDKLLGKGRVNQD- 398
Query: 304 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 483
KA+ + G D A A FV E V E + +K+KVF +++V + I
Sbjct: 399 KANRLKALVTGVLDKAEGFADADFVIEAVFEEMGVKQKVFAEVEAVAPAHAILATNTSSL 458
Query: 484 XXXXXXEGLKHKSQVIVSH 540
LKH +V+ H
Sbjct: 459 SVSEMASKLKHPERVVGFH 477
>UniRef50_Q28KL8 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=2; Bacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase NAD-binding - Jannaschia sp. (strain CCS1)
Length = 466
Score = 50.0 bits (114), Expect = 8e-05
Identities = 36/115 (31%), Positives = 56/115 (48%), Gaps = 4/115 (3%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDV---VAKQITDAIEDIKYQLHTLENDGLL-R 294
K I+G G+IG WA F G+ V +YD ++I + +++ + L L + L
Sbjct: 2 KTAIIGGGVIGGGWAARFLLNGWNVAIYDPDPEAERKIGEVMDNARRALPGLYDTALPPE 61
Query: 295 GELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
G L+ ++ DL AV A +VQE VPE LD+K KV L ++ +
Sbjct: 62 GTLRFTD---------DLGDAVGDADWVQESVPERLDIKHKVHAELTTLAPGRAV 107
>UniRef50_A4YDR4 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=2; Sulfolobaceae|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Metallosphaera sedula DSM 5348
Length = 334
Score = 50.0 bits (114), Expect = 8e-05
Identities = 31/108 (28%), Positives = 55/108 (50%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 306
K+ ++GSG++G +FA G++VT+YDV + + A+E I++ L L+ G ++
Sbjct: 2 KVFVIGSGVMGSGIGQVFAMAGHEVTLYDVKEEALKKAMEGIRWSLQKLQEKGSVK---D 58
Query: 307 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDD 450
I S DL+ A V E V E++ +K V + + D+
Sbjct: 59 VESVLSRIFTSRDLSEARDHLVI--EAVFEDIKVKSDVLGRVSPLTDE 104
Score = 33.5 bits (73), Expect = 7.4
Identities = 13/48 (27%), Positives = 30/48 (62%)
Frame = +2
Query: 569 LXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAI 712
L E++ T E ++ +I++ +G+ P+ + +++ GFV+NRI + +
Sbjct: 142 LVEVIRGDNTSEERFREALDIVKSLGKYPLPVRKDVFGFVVNRILFRL 189
>UniRef50_Q7VRZ0 Cluster: Probable enoyl-CoA
hydratase/3-hydroxyacyl-CoA dehydrogenase, bifunctional
enzyme; n=3; Bordetella|Rep: Probable enoyl-CoA
hydratase/3-hydroxyacyl-CoA dehydrogenase, bifunctional
enzyme - Bordetella pertussis
Length = 705
Score = 49.6 bits (113), Expect = 1e-04
Identities = 32/103 (31%), Positives = 53/103 (51%)
Frame = +1
Query: 136 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASE 315
+VG+G +GR A+ A G +V DV + A+E I+ +L G + E A +
Sbjct: 308 VVGAGTMGRGIAIALADAGLRVRFIDVEQASLDRALEAIRAHYRSLAARGRMT-EAAARD 366
Query: 316 QFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVV 444
I ++D+ A + V V E E+L +K+ +F+ LDS+V
Sbjct: 367 AVARISPASDMQAAAEADVVV-EAAFEDLAIKQAIFRQLDSIV 408
>UniRef50_Q28UL9 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=3; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding - Jannaschia
sp. (strain CCS1)
Length = 687
Score = 49.6 bits (113), Expect = 1e-04
Identities = 37/113 (32%), Positives = 53/113 (46%), Gaps = 2/113 (1%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL- 303
KI IVG G +G A SVG V + + A DAI ++ + TL GL RG L
Sbjct: 284 KIAIVGGGTMGAGIAYACLSVGLPVVLLETDA----DAIARAQHNIDTLIGAGLKRGRLD 339
Query: 304 -KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
+ + T+ A A V E E++D+KK +F LD+ V +T+
Sbjct: 340 DSGAAALRDRLTLTEDYAAASDATLVIEAAFESMDVKKDIFAKLDAAVSPDTV 392
>UniRef50_Q5LPZ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=5; Bacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Silicibacter pomeroyi
Length = 317
Score = 49.2 bits (112), Expect = 1e-04
Identities = 36/113 (31%), Positives = 56/113 (49%), Gaps = 2/113 (1%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVY--DVVAKQITDAIEDIKYQLHTLENDGLLRGE 300
++ +G G IG WA F + GY VT Y D + I D + +L GL G
Sbjct: 11 RVTSIGGGPIGGGWAAHFLARGYDVTSYLHDRAEEGAFRTILDTAWI--SLTALGLAPGA 68
Query: 301 LKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
+ ++ + + DL AV GA F+QE PENL +K+ ++ L +V +N +
Sbjct: 69 --SLDRLRVVH---DLDAAVAGAGFIQESAPENLAMKQALYHRLGRIVPENVV 116
Score = 36.3 bits (80), Expect = 1.1
Identities = 19/52 (36%), Positives = 26/52 (50%)
Frame = +2
Query: 566 PLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDE 721
PL EIV T P + E G+ P+ + +EI GFV R+Q A+ E
Sbjct: 152 PLVEIVGGERTDPAAVEWAGEFYRVAGKAPLMMKKEIPGFVATRLQEALWRE 203
>UniRef50_Q9YBW6 Cluster: 3-hydroxyacyl-CoA
dehydrogenase/3-hydroxybutyryl-CoA dehydratase; n=19;
cellular organisms|Rep: 3-hydroxyacyl-CoA
dehydrogenase/3-hydroxybutyryl-CoA dehydratase -
Aeropyrum pernix
Length = 669
Score = 49.2 bits (112), Expect = 1e-04
Identities = 36/126 (28%), Positives = 65/126 (51%), Gaps = 7/126 (5%)
Frame = +1
Query: 103 MASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLEND 282
MA + K+ I +VG+G +G A L A G++V + D+ + +A++ I++ L L
Sbjct: 1 MAGEVKT--ITVVGAGTMGHGIAELAAIAGFKVYLADINIDILNNALQRIRWSLEKLAEK 58
Query: 283 GLLRGELKA--SEQFQCI-----KGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSV 441
G +R ++ S + + S DLA A+ + F+ E +PE L+LK+++F D
Sbjct: 59 GRIRESVETVMSRITPIVSVRDGEYSEDLAKALSESDFMIEAIPEKLELKQQLFAFADKH 118
Query: 442 VDDNTI 459
+ I
Sbjct: 119 AKETAI 124
Score = 37.5 bits (83), Expect = 0.46
Identities = 15/48 (31%), Positives = 29/48 (60%)
Frame = +2
Query: 557 ITYPLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 700
+ PL E+V T E T ++ +++G+Q V + +++ GF++NRI
Sbjct: 157 VLMPLVEVVKGEKTSEETVAATVDLAKKMGKQTVVVKKDVPGFIVNRI 204
>UniRef50_Q9XA30 Cluster: Putative 3-Hydroxyacyl-CoA dehydrogenase;
n=2; Streptomyces|Rep: Putative 3-Hydroxyacyl-CoA
dehydrogenase - Streptomyces coelicolor
Length = 504
Score = 48.8 bits (111), Expect = 2e-04
Identities = 30/113 (26%), Positives = 56/113 (49%)
Frame = +1
Query: 121 SEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGE 300
S + +VG+G +G+ A + G+ V +YD V + +A + I +L L L G
Sbjct: 7 SSPVAVVGTGTMGQGIAQVALVAGHPVRLYDAVDGRAREAADAIGARLDRLVEKDRLTGA 66
Query: 301 LKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
+ + + + + T + V E V E LD+K+++F+ L+ VV D+ +
Sbjct: 67 ERDAARARLVPAGT--LGELADCALVVEAVVERLDVKQELFRALEDVVGDDCL 117
>UniRef50_Q11TH9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=16;
Bacteroidetes|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Length = 298
Score = 48.8 bits (111), Expect = 2e-04
Identities = 35/108 (32%), Positives = 49/108 (45%)
Frame = +1
Query: 136 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASE 315
I+GSG +G A FA G+QV + D A + A+ I L + G++ K +
Sbjct: 10 IIGSGTMGSGIAHSFAQFGFQVFLCDSNAAALNKAMLQISTNLERQISKGIIPDSEKET- 68
Query: 316 QFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
I TD A K V E VPE L++K +F+ LD TI
Sbjct: 69 IISRITPITDFKEAAKTVSLVVEAVPELLEIKADLFKELDMHCPPETI 116
>UniRef50_Q6V1N6 Cluster: PlmT8; n=1; Streptomyces sp. HK803|Rep:
PlmT8 - Streptomyces sp. HK803
Length = 571
Score = 48.4 bits (110), Expect = 2e-04
Identities = 32/113 (28%), Positives = 55/113 (48%)
Frame = +1
Query: 121 SEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGE 300
+ +IG+VGSG + A A GY T+ + +A+ ++ L+ G L E
Sbjct: 290 ARRIGVVGSGTMATGIAQACARAGYPTTLVARSEVRAKEALATVENSLNRAVQRGRLTPE 349
Query: 301 LKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
+ + + + G + L AV V E V E++D+K+ VF+ LD+V T+
Sbjct: 350 -QLTSSMESLTGVSRL-EAVAACDLVVEAVVEDIDVKRTVFRELDAVCGAQTV 400
>UniRef50_Q0RVG8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 288
Score = 48.4 bits (110), Expect = 2e-04
Identities = 23/56 (41%), Positives = 32/56 (57%)
Frame = +2
Query: 566 PLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRL 733
PL E+VP+P T+P+V + G+ V L RE GFV NR+Q A++ E L
Sbjct: 127 PLVEVVPSPDTRPDVVSAVTSALVAAGKTVVPLNREAPGFVANRLQAALVREAMAL 182
Score = 34.3 bits (75), Expect = 4.3
Identities = 27/113 (23%), Positives = 54/113 (47%)
Frame = +1
Query: 121 SEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGE 300
+ +I + G+G++GR A++ A G++V++YD A D+ +
Sbjct: 3 ASQISVFGAGIMGRGIAVVLADAGHRVSLYDARA--------DVARE------------- 41
Query: 301 LKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
A+ I+ S + AV+G+ + E V ENL++K+ +F ++ + I
Sbjct: 42 --AAAAHPNIEASDTIEAAVEGSSLLFEAVVENLEVKRDLFAEIERFSESTPI 92
>UniRef50_A4ALU9 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like
protein; n=1; marine actinobacterium PHSC20C1|Rep:
3-hydroxyacyl-CoA dehydrogenase-like protein - marine
actinobacterium PHSC20C1
Length = 288
Score = 48.4 bits (110), Expect = 2e-04
Identities = 41/142 (28%), Positives = 57/142 (40%), Gaps = 4/142 (2%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 306
K+ +VGSG +G L A G V V+DV + A + L + +R E
Sbjct: 5 KLAVVGSGTMGHGIGQLAAMQGIAVRVFDVDEVALDRARASVATSL-----ERFVRKETI 59
Query: 307 ASEQFQCIKG----STDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXX 474
Q I+G +TDL A+ G E VPE L LK+KVF +LD +
Sbjct: 60 TDAQSHEIQGRMDWTTDLDAALVGVEAAIEAVPEVLALKQKVFTDLDERTGPEVMLATNT 119
Query: 475 XXXXXXXXXEGLKHKSQVIVSH 540
KH +V+ H
Sbjct: 120 SQLSITTIASSAKHPERVVGMH 141
>UniRef50_A1SPQ6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3;
Actinomycetales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Nocardioides sp. (strain BAA-499 / JS614)
Length = 287
Score = 48.4 bits (110), Expect = 2e-04
Identities = 23/53 (43%), Positives = 32/53 (60%)
Frame = +2
Query: 575 EIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRL 733
E+VP P T + +++E +G+ PV L +EI GFV NRI A+ DE RL
Sbjct: 153 EVVPGPETSGQTVASCVDLVESLGKVPVVLEKEIPGFVANRILNAVRDEAIRL 205
Score = 43.6 bits (98), Expect = 0.007
Identities = 29/109 (26%), Positives = 54/109 (49%), Gaps = 1/109 (0%)
Frame = +1
Query: 136 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQL-HTLENDGLLRGELKAS 312
+VG+G +G AM+ A G+QV ++DV + A +++ ++ +E ++ A+
Sbjct: 6 VVGAGAMGSQIAMVCALAGHQVCLHDVDPAMLERADRELRDRMARQVEKGRRTADDVTAA 65
Query: 313 EQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
+ + S A A A V E V E +++K ++F LD + TI
Sbjct: 66 FERLRVADSLAAAAAAADADLVIEAVVERIEVKSELFAELDRLCPPATI 114
>UniRef50_Q89HA7 Cluster: Blr6087 protein; n=6; Proteobacteria|Rep:
Blr6087 protein - Bradyrhizobium japonicum
Length = 330
Score = 48.0 bits (109), Expect = 3e-04
Identities = 37/118 (31%), Positives = 60/118 (50%), Gaps = 8/118 (6%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDV-------VAKQITDAIEDIKYQLHTLENDGL 288
I +G+G +GR A+ FA G++VT+ DV AK TDA+ +++ +L N GL
Sbjct: 7 IACLGAGRMGRGIAVAFAYAGHRVTMIDVKPRSAEDFAKLETDALGEVRKTFASLSNLGL 66
Query: 289 L-RGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
L ++ + ++ TA+ A V E VPE ++LK++V V +TI
Sbjct: 67 LTEADVDPLVARVSVATASQSGTALADAGMVFEGVPEVVELKREVLGAASRQVKPDTI 124
>UniRef50_Q1IMY8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Acidobacteria bacterium Ellin345|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Acidobacteria bacterium (strain Ellin345)
Length = 278
Score = 48.0 bits (109), Expect = 3e-04
Identities = 30/110 (27%), Positives = 57/110 (51%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
I ++G+G +GRS A A G++ + D++ + A + I+ +L + G + + +A
Sbjct: 7 IAVIGAGTMGRSIAQAAAVGGFRTILEDILPNALRKAEDAIRAELGRAVSTGSVE-QREA 65
Query: 310 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
I+ +++L A + A V E VP+ L+ K ++F LD V T+
Sbjct: 66 DAALARIEYASNLEDAARDADMVIEAVPDELESKLEIFVLLDKVCRPETM 115
>UniRef50_O44608 Cluster: Hydroxy-acyl-coa dehydrogenase protein 1;
n=2; Caenorhabditis|Rep: Hydroxy-acyl-coa dehydrogenase
protein 1 - Caenorhabditis elegans
Length = 299
Score = 48.0 bits (109), Expect = 3e-04
Identities = 32/115 (27%), Positives = 52/115 (45%), Gaps = 7/115 (6%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK- 306
+ I G+G++G A + GY V +Y K++ +A E IK L + + ++
Sbjct: 13 VAIFGAGMMGSGIAQVCLQAGYPVNLYGRSEKKLLEARETIKKNLIRVASKKKTDVPMEP 72
Query: 307 ------ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDN 453
A Q ++ TD+ +A + A E V ENLDLK +FQ + N
Sbjct: 73 AALEEIAQIQLDLLQIHTDIPSAAEDAAMAIEAVAENLDLKLDIFQTIQKTCPQN 127
>UniRef50_Q4J6T7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Archaea|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Sulfolobus acidocaldarius
Length = 657
Score = 48.0 bits (109), Expect = 3e-04
Identities = 31/112 (27%), Positives = 56/112 (50%), Gaps = 1/112 (0%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 306
++G+VG+G +G A + A G+ V + DV + +A+E I++ L L + ++K
Sbjct: 6 RVGVVGAGTMGHGIAEVVAIAGFNVVLTDVNEDILRNALEKIRWSLEKLRE----KRQIK 61
Query: 307 ASEQFQCIKGSTDLATAVKGAV-FVQECVPENLDLKKKVFQNLDSVVDDNTI 459
+ + T ++ V F+ E E D+K+K+F LD VV + I
Sbjct: 62 ENPNTVLSRIKTTVSFGDFSDVDFIIEAAIERSDVKRKIFSELDRVVKKDAI 113
Score = 33.9 bits (74), Expect = 5.6
Identities = 15/48 (31%), Positives = 28/48 (58%)
Frame = +2
Query: 557 ITYPLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 700
+ PL EI+ T E K T ++ ++I + V + +++ GF++NRI
Sbjct: 146 VLMPLVEIIMGNKTAEETLKTTIDLAKKINKDYVVVKKDVPGFLINRI 193
>UniRef50_Q0LZ25 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Caulobacter sp. K31|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Caulobacter sp. K31
Length = 296
Score = 47.6 bits (108), Expect = 4e-04
Identities = 27/84 (32%), Positives = 44/84 (52%)
Frame = +2
Query: 569 LXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLXXXXX 748
L E+VPA T PE T +++ IG+QP+++ +++ GF +NR+ +A+L E RL
Sbjct: 164 LVEVVPAFETSPETVAWTTSLLKRIGKQPIAV-KDVPGFAVNRMLHAMLIEAVRLVEEGV 222
Query: 749 XXXXXXXXXMSEGLGXEICIFGVL 820
GLG I F ++
Sbjct: 223 ATPEDLDTACRLGLGHPIGPFALM 246
Score = 40.7 bits (91), Expect = 0.049
Identities = 38/113 (33%), Positives = 59/113 (52%), Gaps = 4/113 (3%)
Frame = +1
Query: 109 SKFKSE-KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDG 285
S F E KIG+VG+GL+G A++FA G V ++D A A+E +L L + G
Sbjct: 10 SPFAPELKIGVVGAGLMGAEIALVFALGGMDVLLHDRDAA----ALEKALARLSALLDRG 65
Query: 286 LLRG---ELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLD 435
+ RG E + + + I+ + DL + V E V E+L++K +V LD
Sbjct: 66 VSRGLYTEGRRATALENIRLAPDL-SRFGDRDLVTEAVFESLEVKGQVLAALD 117
>UniRef50_A6ERZ1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
unidentified eubacterium SCB49|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - unidentified eubacterium SCB49
Length = 403
Score = 47.6 bits (108), Expect = 4e-04
Identities = 34/112 (30%), Positives = 55/112 (49%), Gaps = 2/112 (1%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
IGI+G+G +G A + A+ G V ++D+ + A ++ + L G + E KA
Sbjct: 20 IGIIGAGTMGSGIAQVAATAGCTVKLFDLNQAALDKAKASLEKIMTRLVEKGRVTEEEKA 79
Query: 310 --SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
E + +LA + E + E+L +KKKVFQ L+S V D+ I
Sbjct: 80 RIQENISYVNALKELADSD----LTIEAIIEDLGIKKKVFQELESYVSDSCI 127
>UniRef50_A4FKS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Actinomycetales|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Saccharopolyspora erythraea
(strain NRRL 23338)
Length = 303
Score = 47.6 bits (108), Expect = 4e-04
Identities = 26/83 (31%), Positives = 35/83 (42%)
Frame = +2
Query: 566 PLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLXXXX 745
PL EIVP T+ V + +G+ PV L +E+ GFV NR+Q A++ E L
Sbjct: 138 PLVEIVPGERTEERVTEAATAFYTALGKTPVRLRKEVPGFVANRLQSAVMREATHLVLEG 197
Query: 746 XXXXXXXXXXMSEGLGXEICIFG 814
M LG G
Sbjct: 198 VVRADELDTVMKSSLGGRYAAVG 220
Score = 39.9 bits (89), Expect = 0.086
Identities = 33/102 (32%), Positives = 52/102 (50%), Gaps = 3/102 (2%)
Frame = +1
Query: 136 IVGSGLIGRSWAMLFASVGYQVTVYDV---VAKQITDAIEDIKYQLHTLENDGLLRGELK 306
+VG+G IG WA LF++ G +V + D +A + DA+ + + + D LL G
Sbjct: 1 MVGAGTIGLGWAALFSAHGLEVRITDPRDDLASVVGDAMPLLAESMGR-DPDQLLAG--- 56
Query: 307 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNL 432
I+ + LA AV A VQE PE L+ K+ +F ++
Sbjct: 57 -------IEIADSLADAVSDADLVQENGPERLEFKQDLFADI 91
>UniRef50_Q0UZL9 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 308
Score = 47.6 bits (108), Expect = 4e-04
Identities = 21/52 (40%), Positives = 32/52 (61%)
Frame = +2
Query: 566 PLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDE 721
PL E+VP+ T V +T++ E G+ P+ + RE GFV NR+ +A+L E
Sbjct: 145 PLLELVPSSETSDTVISRTQDFWRERGRVPIHIKRETTGFVANRLAFALLRE 196
Score = 40.3 bits (90), Expect = 0.065
Identities = 35/140 (25%), Positives = 68/140 (48%), Gaps = 2/140 (1%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAML-FASVG-YQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGE 300
K+ ++G+G IG S+A A + Q+T+YD ++ IE+ L G +
Sbjct: 7 KVTLIGTGTIGLSFAAFHLAKLSPSQLTIYDT-RSDLSTYIEEF---LPKFFESGKSPAD 62
Query: 301 LKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 480
L SE I+ + L AV + +QE PENLD+K+K+++ ++ ++ +
Sbjct: 63 L--SE----IRLAVTLQEAVSDSHIIQESGPENLDVKRKLWKEVEKYAPNDALLWSSTSG 116
Query: 481 XXXXXXXEGLKHKSQVIVSH 540
+ ++ K++++V H
Sbjct: 117 IPASQQAQDMQDKTRLLVVH 136
>UniRef50_P34439 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenase
F54C8.1; n=2; Caenorhabditis|Rep: Probable
3-hydroxyacyl-CoA dehydrogenase F54C8.1 - Caenorhabditis
elegans
Length = 298
Score = 47.6 bits (108), Expect = 4e-04
Identities = 37/137 (27%), Positives = 62/137 (45%), Gaps = 5/137 (3%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
+ IVGSG +G A + AS G+ V + DV K + A++ I + L +G K
Sbjct: 14 VAIVGSGQMGSGIAQVTASSGFNVMLADVNKKALDRAMKAISQSVTHLSKKQ--KGTDKE 71
Query: 310 SEQFQC-----IKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXX 474
F IK +++TAV A + E EN+DLK+ +F ++ ++I
Sbjct: 72 KSDFVTLTMSRIKTCNNVSTAVADADLIIEAAIENIDLKRGIFAQIEQSCKKDSILTTNT 131
Query: 475 XXXXXXXXXEGLKHKSQ 525
+GL+ K++
Sbjct: 132 SSFLLEDVAKGLQDKTR 148
>UniRef50_A3U7V8 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerasefamily protein; n=19; Bacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerasefamily protein - Croceibacter
atlanticus HTCC2559
Length = 802
Score = 47.2 bits (107), Expect = 6e-04
Identities = 38/133 (28%), Positives = 70/133 (52%), Gaps = 16/133 (12%)
Frame = +1
Query: 109 SKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITD-------AIEDIKYQLH 267
+K + KI ++GSG++G A FA++G +V + D+V +++ + +ED K +
Sbjct: 2 AKRRINKIAVIGSGIMGSGIACHFANIGVEVLLLDIVPRELNEKEKAKGLTLED-KVVRN 60
Query: 268 TLENDGLLRGELKAS------EQF--QCIKGS-TDLATAVKGAVFVQECVPENLDLKKKV 420
+ ND L+ +K+ + F + G+ D VK ++ E V E LD+KK+V
Sbjct: 61 RIVNDA-LQSSIKSKPAPLYHKDFASRISTGNLEDDIAKVKDVDWIIEVVVERLDIKKQV 119
Query: 421 FQNLDSVVDDNTI 459
F+NL+ + T+
Sbjct: 120 FENLEKHRTEGTL 132
>UniRef50_Q84T13 Cluster: L-3-hydroxyacyl-CoA dehydrogenase subunit
precursor; n=1; Euglena gracilis|Rep:
L-3-hydroxyacyl-CoA dehydrogenase subunit precursor -
Euglena gracilis
Length = 320
Score = 47.2 bits (107), Expect = 6e-04
Identities = 33/117 (28%), Positives = 56/117 (47%), Gaps = 7/117 (5%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG---- 297
+G+VG G +G A + A+ GY+V D+ A ++ I+ ++ L + + G
Sbjct: 25 VGVVGMGAMGHGIAQMTAAAGYKVVAVDIDANMLSKGIKAVEDSLSKVAAKAVKDGKADK 84
Query: 298 ---ELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
E A++ I S D+ A+ V E + E+L++KKK F +L V N I
Sbjct: 85 ATAEKNAADVRSRITTSGDIG-ALSSCDLVIESIIEDLNIKKKFFADLGKVAGANAI 140
>UniRef50_A7PEM6 Cluster: Chromosome chr11 scaffold_13, whole genome
shotgun sequence; n=3; core eudicotyledons|Rep:
Chromosome chr11 scaffold_13, whole genome shotgun
sequence - Vitis vinifera (Grape)
Length = 724
Score = 47.2 bits (107), Expect = 6e-04
Identities = 32/139 (23%), Positives = 61/139 (43%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 303
+K+ ++G GL+G A + V + +V ++ + I+ I+ + L G L +
Sbjct: 309 KKVAVIGGGLMGSGIATALITSNIYVVLKEVNSEYLLKGIKTIEANVRGLVTKGKLTQD- 367
Query: 304 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 483
KA + +KG D + K V E V EN+ LK+K+F ++ + + I
Sbjct: 368 KARKALSMLKGVLDYSE-FKDIDMVIEAVIENISLKQKIFSEIEKICSPHCILATNTSTI 426
Query: 484 XXXXXXEGLKHKSQVIVSH 540
E + ++I +H
Sbjct: 427 DLNLVGEKTSSQDRIIGAH 445
>UniRef50_Q7D836 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=8; Mycobacterium tuberculosis complex|Rep:
3-hydroxyacyl-CoA dehydrogenase family protein -
Mycobacterium tuberculosis
Length = 304
Score = 46.8 bits (106), Expect = 7e-04
Identities = 18/52 (34%), Positives = 35/52 (67%)
Frame = +2
Query: 566 PLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDE 721
P+ E+VP+ T P+ A + ++ ++G+ PV + R++ GF+ NR+Q+A+ E
Sbjct: 139 PVVEVVPSARTAPDTADRVVALLTQVGKLPVRVGRDVPGFIGNRLQHALWRE 190
Score = 40.3 bits (90), Expect = 0.065
Identities = 33/108 (30%), Positives = 52/108 (48%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 306
+ +VG+GL+GR A + AS G V + D A+ + A + G RG +
Sbjct: 9 RAAVVGAGLMGRRIAGVLASAGLDVAITDTNAEILHAA------AVEAARVAGAGRGSVA 62
Query: 307 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDD 450
A + DLA A+ A V E V ENL +K+++F+ L ++ D
Sbjct: 63 A---------AADLAAAIPDADLVIEAVVENLAVKQELFERLATLAPD 101
>UniRef50_Q47M90 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5;
root|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Thermobifida fusca (strain YX)
Length = 398
Score = 46.8 bits (106), Expect = 7e-04
Identities = 35/110 (31%), Positives = 54/110 (49%), Gaps = 4/110 (3%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDA-IEDIKYQLHTLENDGLLRGEL 303
K+G+VG G +G +FA G+ VT +I DA +E + L + +G+L
Sbjct: 7 KVGVVGLGTMGAGIVEVFARAGFTVT-----GVEIDDAALERGRTHLEKSLAKAVAKGKL 61
Query: 304 KASEQFQCIKGSTDLATA---VKGAVFVQECVPENLDLKKKVFQNLDSVV 444
EQ + I G T+ + A E VPE LD+K+ VF +LD ++
Sbjct: 62 TEDEQ-RAILGRVTFTTSRDDLADAHLAVEAVPERLDIKRSVFADLDRIL 110
>UniRef50_Q4J598 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD
binding domain; n=2; Azotobacter vinelandii|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD binding domain -
Azotobacter vinelandii AvOP
Length = 208
Score = 46.8 bits (106), Expect = 7e-04
Identities = 33/137 (24%), Positives = 64/137 (46%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
I I+GSG +G A A G++V + +Q+ + + + L L G E A
Sbjct: 6 IAILGSGSMGVGIATHLARHGHEVLLIYPSMEQLAEVLAMARSILAGLVEAGRFAPEQVA 65
Query: 310 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 489
+ + ++ ST L V G + E +PE ++LK+ ++ L+ +VD +
Sbjct: 66 ATLAR-LRTSTRLKD-VAGVRLLIETLPERIELKRALYAELERIVDAEAVIASDTGGLSP 123
Query: 490 XXXXEGLKHKSQVIVSH 540
EG++H +++++H
Sbjct: 124 ERLAEGMRHPGRLLIAH 140
>UniRef50_Q876X5 Cluster: Dehydrogenase; n=7; Pezizomycotina|Rep:
Dehydrogenase - Fusarium sporotrichioides
Length = 285
Score = 46.8 bits (106), Expect = 7e-04
Identities = 34/110 (30%), Positives = 54/110 (49%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
+ ++G G++GR A +A+ GY V + D +Q A+E + D +RG ++A
Sbjct: 14 VAVLGGGVLGRRIACGWAASGYDVIIRDPSHEQRVAAVEYCNTSMSKYP-DSNVRGSIQA 72
Query: 310 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
E DL AV A V E VPE L +K F +L+ + ++TI
Sbjct: 73 VE---------DLPEAVAKAWLVIETVPEKLPIKIATFTDLERLTSEDTI 113
>UniRef50_Q4PFL4 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 344
Score = 46.4 bits (105), Expect = 0.001
Identities = 39/123 (31%), Positives = 59/123 (47%), Gaps = 8/123 (6%)
Frame = +1
Query: 91 STVIMASKFKSEKIGIVGSGLIGRSWAMLFASVG-YQVTVYDVVAKQITDAIEDIKYQLH 267
ST ++ +K + I + G+GL+G A + A G + VT+ DV K + + I L
Sbjct: 32 STSLVQNK-DVQNITVFGAGLMGAGIAQVLAHKGKFNVTLSDVTDKALANGQTIISKSLG 90
Query: 268 TLENDGLLRGELKASEQFQCIKG-------STDLATAVKGAVFVQECVPENLDLKKKVFQ 426
+ + E A EQ Q +KG +TD AVK V E + EN+ +KK +F
Sbjct: 91 RIVKKSM--AEASAEEQAQYVKGIVDSIKVTTDPEAAVKDTDLVIEAIIENVGIKKDLFG 148
Query: 427 NLD 435
LD
Sbjct: 149 FLD 151
>UniRef50_A2QA05 Cluster: Catalytic activity:; n=4;
Trichocomaceae|Rep: Catalytic activity: - Aspergillus
niger
Length = 622
Score = 46.4 bits (105), Expect = 0.001
Identities = 33/105 (31%), Positives = 49/105 (46%)
Frame = +1
Query: 118 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG 297
KS I I+G+G++GR A +F+S GY V + D + A I +H + R
Sbjct: 13 KSRPIVIIGAGILGRRIAAVFSSAGYSVHISDPSPSALDSARTYISTHIHEFTTH-IPRP 71
Query: 298 ELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNL 432
L I T + AV A + E VPE L +K+ +F +L
Sbjct: 72 SLSPGP----ISTFTSVPEAVATAWLIVEAVPEILPIKQSLFADL 112
>UniRef50_A7D676 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Halorubrum lacusprofundi ATCC
49239|Rep: 3-hydroxyacyl-CoA dehydrogenase, NAD-binding
- Halorubrum lacusprofundi ATCC 49239
Length = 676
Score = 46.4 bits (105), Expect = 0.001
Identities = 28/104 (26%), Positives = 53/104 (50%), Gaps = 1/104 (0%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTL-ENDGLLRGE 300
+++ ++G+G +G A + A GY V + D+ + + + I++ L L E D + GE
Sbjct: 20 QRVTVLGAGNMGHGIAEVAALAGYDVALRDIEEEFVQGGYDQIEWSLGKLAEKDRI--GE 77
Query: 301 LKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNL 432
+A ++ DL ++ A V E VPE + +KK V+ +
Sbjct: 78 DEADAALDRVEAFVDLEDSLADADVVVEVVPEKMAIKKDVYDEV 121
Score = 33.1 bits (72), Expect = 9.8
Identities = 13/51 (25%), Positives = 28/51 (54%)
Frame = +2
Query: 569 LXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDE 721
L E++ T + + + E +G+ PV + ++ GF++NRI +++E
Sbjct: 167 LVEVISGKHTSEDTLELIEGLAESMGKTPVRVRKDSPGFIVNRILVPLMNE 217
>UniRef50_Q5LKF7 Cluster: Fatty oxidation complex, alpha subunit;
n=5; Bacteria|Rep: Fatty oxidation complex, alpha
subunit - Silicibacter pomeroyi
Length = 714
Score = 46.0 bits (104), Expect = 0.001
Identities = 33/116 (28%), Positives = 59/116 (50%), Gaps = 2/116 (1%)
Frame = +1
Query: 118 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG 297
K +++GI+G+G++G+ A A+ G V + D Q +A E K TL + + +G
Sbjct: 316 KVQRLGILGAGMMGQGIAFSAATAGLPVVLKD----QTLEAAERGKAYTATLLDKRVKQG 371
Query: 298 ELKASEQ--FQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
+ A E+ + TD A +KG + E V E +D+K V ++++ +N I
Sbjct: 372 RMSAEEREAVLALITPTDKADDLKGCDLIIEAVFEKIDIKDAVLAEHEALLAENGI 427
>UniRef50_Q2S2J8 Cluster: Fatty oxidation complex, alpha subunit;
n=2; Bacteria|Rep: Fatty oxidation complex, alpha
subunit - Salinibacter ruber (strain DSM 13855)
Length = 719
Score = 46.0 bits (104), Expect = 0.001
Identities = 33/139 (23%), Positives = 63/139 (45%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 303
+ +G++G+GL+G A + A G V + D + + I + E+ G++
Sbjct: 319 DTVGVLGAGLMGSGIAQVSAQNGLDVVLTDQSLALAAEGKKAIWSAVTEQEDKGIIN-TF 377
Query: 304 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 483
+ + + + D A ++ A V E VPE+L +K V +++VVD +T+
Sbjct: 378 TRDQIVERVAPTADYAP-LQAADVVIEAVPEDLSIKHAVLSEVETVVDADTVLASNTSAL 436
Query: 484 XXXXXXEGLKHKSQVIVSH 540
EG+ S+V+ H
Sbjct: 437 PISTIAEGVDDPSRVLGMH 455
>UniRef50_Q0FUM2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Rhodobacterales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Roseovarius sp. HTCC2601
Length = 220
Score = 46.0 bits (104), Expect = 0.001
Identities = 32/114 (28%), Positives = 54/114 (47%), Gaps = 1/114 (0%)
Frame = +1
Query: 121 SEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGE 300
S +I +VG+G +G A L+A GY + D + +E + L D
Sbjct: 13 SGRICVVGAGFMGCVIATLYAHHGYDAVICDSNQTMLDTYVERARPIAAGLVEDS----- 67
Query: 301 LKASEQFQC-IKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
ASE + DLA+A++G V E V E+L++K+ +F L+ + +N +
Sbjct: 68 -DASEAMLAGVTLEPDLASAIEGVFLVHEAVQESLEVKQALFAELERICPENVV 120
Score = 39.1 bits (87), Expect = 0.15
Identities = 23/66 (34%), Positives = 40/66 (60%), Gaps = 4/66 (6%)
Frame = +2
Query: 548 IHLIT----YPLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 715
IH +T P+ E++ A T E+ +R +++ I V++ E GF++NRIQ+A+L
Sbjct: 146 IHYVTPGHIVPVIELIHAADTPAELVAWSRMLVQNIEHVGVAIL-ERPGFLVNRIQFAML 204
Query: 716 DEVWRL 733
E++RL
Sbjct: 205 TEIYRL 210
>UniRef50_A5VHQ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=2; Lactobacillus reuteri|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Lactobacillus reuteri F275
Length = 294
Score = 46.0 bits (104), Expect = 0.001
Identities = 36/113 (31%), Positives = 58/113 (51%), Gaps = 1/113 (0%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 303
+ I I G+G++G A A G+ V+VY+ I A IK E D L +
Sbjct: 2 KNIMIAGAGVLGSQIAYQTALSGFNVSVYN---HHIDTAERRIKALKSDYERD-LHLTDK 57
Query: 304 KASEQFQCIKGSTD-LATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
+ + IK TD +ATAVK A + E +PE+L+LK++ ++ + + + TI
Sbjct: 58 EFQQGLNNIKVITDDVATAVKDADLMIEALPESLELKEQFYEEVSELAPEKTI 110
Score = 33.5 bits (73), Expect = 7.4
Identities = 16/51 (31%), Positives = 27/51 (52%)
Frame = +2
Query: 563 YPLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 715
+ + EI+ T PEV ++ + EI PV L +E G++LN + +L
Sbjct: 145 FNVVEIMGTSQTSPEVIEEATKFAREIKMVPVILNKEQHGYILNSLLIPLL 195
>UniRef50_A5IDB6 Cluster: 3-hydroxyacyl CoA dehydrogenase; n=9;
Gammaproteobacteria|Rep: 3-hydroxyacyl CoA dehydrogenase
- Legionella pneumophila (strain Corby)
Length = 284
Score = 46.0 bits (104), Expect = 0.001
Identities = 31/108 (28%), Positives = 53/108 (49%), Gaps = 3/108 (2%)
Frame = +1
Query: 118 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG 297
K K+ ++G+G +G LFA G+ VT+ D + Q+ A + I LH L L
Sbjct: 2 KQTKLTLLGAGTMGSGITQLFAQYGFYVTLIDNLQSQLDKAKDTIAKNLHYL----ALTQ 57
Query: 298 ELKASEQFQCIKGSTDLAT---AVKGAVFVQECVPENLDLKKKVFQNL 432
L+++ + I S T +K + ++ E + EN + KK ++Q L
Sbjct: 58 NLESTHSIETILASITFTTKLDELKQSEYIIENITENWERKKALYQVL 105
>UniRef50_A0QZR0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Mycobacterium smegmatis str. MC2 155|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Mycobacterium
smegmatis (strain ATCC 700084 / mc(2)155)
Length = 296
Score = 46.0 bits (104), Expect = 0.001
Identities = 34/140 (24%), Positives = 62/140 (44%), Gaps = 3/140 (2%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
+ ++G+G +G A + A G++ +YD+ + I+ + H + + G+L A
Sbjct: 12 VAVLGAGTMGSGIATVMARAGHRTILYDINEANLERGIDTV----HGFFDKSVRLGKLDA 67
Query: 310 S---EQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 480
+ + GST+L V V E V E+L LKK+ F LD +V T+
Sbjct: 68 TAGQAAKDSLSGSTELKDLAPCDVVV-EAVFEDLSLKKETFGRLDDIVPPTTLFHTNTST 126
Query: 481 XXXXXXXEGLKHKSQVIVSH 540
G + + +V+ +H
Sbjct: 127 LSVTGIASGSRLRERVVGTH 146
>UniRef50_Q3A7N5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Pelobacter carbinolicus DSM 2380|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Pelobacter carbinolicus (strain DSM 2380
/ Gra Bd 1)
Length = 304
Score = 45.6 bits (103), Expect = 0.002
Identities = 35/108 (32%), Positives = 50/108 (46%)
Frame = +1
Query: 136 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASE 315
+VG G +GR A A+ GY VT+YD+ A+ + + I L +G ++ + A
Sbjct: 11 VVGGGTMGRQIAFQCAAHGYFVTIYDISAEVLQATQKRIGAYADYLVAEGHIQPQ-AAKR 69
Query: 316 QFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
I STD A A + E VPE+ LK +VF D TI
Sbjct: 70 AINRISISTD-ARQAANADLLCEAVPEDPALKGEVFARFDRYCPQRTI 116
>UniRef50_Q46MP3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
Burkholderiales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Ralstonia eutropha (strain JMP134) (Alcaligenes
eutrophus)
Length = 304
Score = 45.2 bits (102), Expect = 0.002
Identities = 20/52 (38%), Positives = 34/52 (65%)
Frame = +2
Query: 566 PLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDE 721
PL E+V T+ VAK+ + + + G+ PV + R++ GFV NR+Q+A++ E
Sbjct: 144 PLVEVVRGELTREGVAKQVSQWLSKAGKTPVDVYRDVPGFVGNRMQFALVRE 195
>UniRef50_Q9ADL9 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase;
n=7; Bacteria|Rep: Beta-hydroxybutyryl-CoA dehydrogenase
- Polyangium cellulosum (Sorangium cellulosum)
Length = 293
Score = 45.2 bits (102), Expect = 0.002
Identities = 36/140 (25%), Positives = 59/140 (42%), Gaps = 3/140 (2%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
+G+VG+G++G A A G+ V + DV + A I+ L + G + +A
Sbjct: 12 VGVVGAGVMGVGVAQSLAQTGHDVVLVDVSEAALARARMGIRNGLRAVTLFGSAEDKKRA 71
Query: 310 SEQ---FQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX 480
+ + + +TD + GA FV E V E D+K++V+ L+ V I
Sbjct: 72 GDPKAVLERVAFTTDYG-RLAGADFVVENVTEKWDIKREVYARLEGVCRPEIIFAADTSA 130
Query: 481 XXXXXXXEGLKHKSQVIVSH 540
K SQV+ H
Sbjct: 131 ISITRIGSVTKRPSQVVGMH 150
>UniRef50_A4SW21 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=1; Polynucleobacter sp.
QLW-P1DMWA-1|Rep: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor - Polynucleobacter sp.
QLW-P1DMWA-1
Length = 310
Score = 45.2 bits (102), Expect = 0.002
Identities = 21/56 (37%), Positives = 36/56 (64%)
Frame = +2
Query: 566 PLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRL 733
PL E+V + PE+AK ++ + ++PV + ++I GF+ NRIQ+A++ EV L
Sbjct: 142 PLVEVVLGKTSDPELAKTVCQLFQAHHKKPVLVKKDIPGFLANRIQHALMREVLSL 197
>UniRef50_Q2VHK2 Cluster: Oxidoreductase; n=11; Lactobacillales|Rep:
Oxidoreductase - Lactococcus lactis
Length = 449
Score = 44.8 bits (101), Expect = 0.003
Identities = 29/74 (39%), Positives = 40/74 (54%), Gaps = 1/74 (1%)
Frame = +1
Query: 73 SCGTVASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDI 252
S V ST +M K E + I+GSG IG +A +FAS G +VTV D+ + EDI
Sbjct: 146 SRNVVTSTELMDLKQLPEHLTIIGSGYIGLEFASMFASYGSKVTVLDIFDNFLPRDDEDI 205
Query: 253 -KYQLHTLENDGLL 291
K LE+ G++
Sbjct: 206 SKLVRSDLESRGII 219
>UniRef50_Q2UUZ5 Cluster: RIB40 genomic DNA, SC009; n=4;
Trichocomaceae|Rep: RIB40 genomic DNA, SC009 -
Aspergillus oryzae
Length = 337
Score = 44.8 bits (101), Expect = 0.003
Identities = 25/62 (40%), Positives = 36/62 (58%), Gaps = 1/62 (1%)
Frame = +2
Query: 551 HLITYPLXEIVPAPWTKPE-VAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVW 727
HLI PL E+VP T E V + E +G++PV + +EI GF+ NR+Q A+ E +
Sbjct: 167 HLI--PLVEVVPHRTTDRETVVPRAMEFYRSLGKKPVLIQKEIPGFIANRLQAALSMEAY 224
Query: 728 RL 733
L
Sbjct: 225 SL 226
Score = 34.7 bits (76), Expect = 3.2
Identities = 19/56 (33%), Positives = 27/56 (48%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG 297
+ I+G+G+IG SW LF + G +V V D + + Q TL GL G
Sbjct: 12 VAIIGTGVIGASWTALFLARGLKVLVTDPAPNAEKNLETYLNAQWPTLTQIGLSEG 67
>UniRef50_A2QCM7 Cluster: Catalytic activity: precursor; n=5;
Trichocomaceae|Rep: Catalytic activity: precursor -
Aspergillus niger
Length = 338
Score = 44.4 bits (100), Expect = 0.004
Identities = 25/54 (46%), Positives = 32/54 (59%), Gaps = 2/54 (3%)
Frame = +2
Query: 566 PLXEIVPAPWTKPEVAKKTREIMEEIGQQ--PVSLTREIDGFVLNRIQYAILDE 721
PL EIVPAP T E + RE G + PV + +EI GFV NR+ +A+L E
Sbjct: 166 PLLEIVPAPGTSAERVEFAREYFSLPGSRHRPVVIQKEIPGFVGNRLAFALLRE 219
>UniRef50_Q4J0Z7 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
C-terminal:3-hydroxyacyl-CoA dehydrogenase, NAD binding
domain; n=2; Gammaproteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, C-terminal:3-hydroxyacyl-CoA
dehydrogenase, NAD binding domain - Azotobacter
vinelandii AvOP
Length = 307
Score = 44.0 bits (99), Expect = 0.005
Identities = 31/137 (22%), Positives = 61/137 (44%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
I I+G+GL+G A A G+ V + D A+++ + L L + G +
Sbjct: 6 IVILGAGLMGIGIATHLARHGHAVLLRDPAAERLAEVPVMAGSILAELADAGRFE-RAQT 64
Query: 310 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 489
+ S LA + + E +PE L+LK+ ++ L+++V T+
Sbjct: 65 DATLARLAVSPRLADVADARLLI-EAIPERLELKRALYAELEALVGTGTVIASNTSGLPP 123
Query: 490 XXXXEGLKHKSQVIVSH 540
EG++H +++++H
Sbjct: 124 DALAEGMRHPERLLIAH 140
Score = 44.0 bits (99), Expect = 0.005
Identities = 28/90 (31%), Positives = 41/90 (45%)
Frame = +2
Query: 551 HLITYPLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWR 730
HLI PL EIVP T+ E + R ++ + + V L + I GF+ NR+Q+A+L E
Sbjct: 146 HLI--PLVEIVPGSATRAEHLEAVRTLLAGMELEAVVLDKAIPGFIGNRLQFAVLREALH 203
Query: 731 LXXXXXXXXXXXXXXMSEGLGXEICIFGVL 820
+ M LG + G L
Sbjct: 204 IVRSGAASAETVDRVMRASLGRRYAMVGPL 233
>UniRef50_A0Z5J4 Cluster: Enoyl-CoA hydratase; n=2; unclassified
Gammaproteobacteria (miscellaneous)|Rep: Enoyl-CoA
hydratase - marine gamma proteobacterium HTCC2080
Length = 699
Score = 44.0 bits (99), Expect = 0.005
Identities = 30/106 (28%), Positives = 51/106 (48%), Gaps = 2/106 (1%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
+GI+G+G +G AM FA G VT+ D+ + + +E I + +G L
Sbjct: 296 VGIIGAGTMGGGIAMCFAQAGIAVTLVDMTDEAVKGGLEKIAKNYAI----SVKKGRLTV 351
Query: 310 SEQFQCIKGSTDLAT--AVKGAVFVQECVPENLDLKKKVFQNLDSV 441
++ + T ++ + V E V ENL++KK+VF LD +
Sbjct: 352 AQTDAILANITTSSSFDDLANVDMVIEAVFENLEVKKEVFGKLDVI 397
>UniRef50_Q7RZ80 Cluster: Putative uncharacterized protein
NCU04393.1; n=2; Sordariales|Rep: Putative
uncharacterized protein NCU04393.1 - Neurospora crassa
Length = 420
Score = 44.0 bits (99), Expect = 0.005
Identities = 42/152 (27%), Positives = 65/152 (42%), Gaps = 17/152 (11%)
Frame = +1
Query: 136 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDI-----KYQLHTLENDGL---- 288
I+G+G IGR A+++AS VTVYD+ + + E I KY L + G
Sbjct: 97 IMGAGHIGRRVALVWASALRPVTVYDISKNALRSSTEYITDNLAKYCLEHGTHPGPVHFT 156
Query: 289 --LRGELKASEQ------FQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVV 444
LR A ++ F + +T KG V EC+PENL LK ++ ++
Sbjct: 157 SDLREATTAGKRHGLKLDFSAAHDTEPKSTRKKGPWMVIECLPENLSLKIAALAEIERLL 216
Query: 445 DDNTIXXXXXXXXXXXXXXEGLKHKSQVIVSH 540
+N I L+H ++I +H
Sbjct: 217 PENCIIASNSSSLMTSEMAPHLQHPGRLINTH 248
>UniRef50_UPI00006A277A Cluster: UPI00006A277A related cluster; n=1;
Xenopus tropicalis|Rep: UPI00006A277A UniRef100 entry -
Xenopus tropicalis
Length = 666
Score = 43.6 bits (98), Expect = 0.007
Identities = 32/111 (28%), Positives = 53/111 (47%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 306
K+GIVG+G +G AM FA+VG V +V + + + ++ G L E +
Sbjct: 292 KVGIVGAGTMGGGIAMNFANVGIPTVVVEVNDETLQRGLGLVRRNYEASAAKGRLTAE-Q 350
Query: 307 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
+ + ++G+ D A A+ V E V EN+ LK+ + L +V I
Sbjct: 351 VAGRMALLQGALDYA-ALAECDLVIEAVFENMALKQDICAKLGAVAKPGAI 400
>UniRef50_A6X670 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=1; Ochrobactrum anthropi ATCC 49188|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding -
Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 /
NCTC 12168)
Length = 659
Score = 43.6 bits (98), Expect = 0.007
Identities = 33/110 (30%), Positives = 52/110 (47%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
IGI G+GL+G A+ + GY V Y+ A+ I + + G L E A
Sbjct: 297 IGIAGTGLMGSGIAVASLAAGYTVIGYETTAEAAAKGHARITDMIQKAVDTGRLSTE-AA 355
Query: 310 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
Q + S D+A A+ A V E V ++ +K +F+ LD+++ TI
Sbjct: 356 DAQRSKLSVSADMA-ALADADLVIEAVFDDFTVKASLFRELDALLPPATI 404
>UniRef50_Q9RUA4 Cluster: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA
isomerase/3-hydroxyacyl-CoA dehydrogenase; n=18;
Bacteria|Rep: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA
isomerase/3-hydroxyacyl-CoA dehydrogenase - Deinococcus
radiodurans
Length = 708
Score = 43.2 bits (97), Expect = 0.009
Identities = 29/109 (26%), Positives = 49/109 (44%)
Frame = +1
Query: 133 GIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKAS 312
GI+G+G +G AM F +VG VT+ + + + + I+ G + +
Sbjct: 311 GIIGAGTMGGGIAMNFLNVGIPVTIVETSQEALDRGLGVIRKNYENTAKKGRMTQD--DV 368
Query: 313 EQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
E+ + T + GA + E V EN+D+KK +F LD + I
Sbjct: 369 EKRMGLLTPTLKMEDLAGADIIIEAVFENMDVKKDIFTRLDKIAKPGAI 417
>UniRef50_Q5HKI5 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=3; Staphylococcus|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Staphylococcus
epidermidis (strain ATCC 35984 / RP62A)
Length = 321
Score = 43.2 bits (97), Expect = 0.009
Identities = 32/138 (23%), Positives = 52/138 (37%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 306
K +VG+G+IG W + G++V D + +K E GL
Sbjct: 2 KFAVVGTGVIGSGWITRMLAHGHEVIATDPSEGAYERMLTQVKQNWPYAEQMGLAE---- 57
Query: 307 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 486
+ Q + + L AVK A +QE VPE ++K V + +D
Sbjct: 58 -NASIQNLTFTPHLEEAVKDADHIQENVPEVEEIKDAVLKEIDFYAKPEATIGSSTSGIM 116
Query: 487 XXXXXEGLKHKSQVIVSH 540
L H +++V+H
Sbjct: 117 PSELQANLSHPERLVVAH 134
Score = 39.5 bits (88), Expect = 0.11
Identities = 19/52 (36%), Positives = 27/52 (51%)
Frame = +2
Query: 566 PLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDE 721
PL EIVP T E K +I E IG + + EI+G + +R+ A+ E
Sbjct: 143 PLVEIVPGKQTSEETTVKAEQIYESIGMDVLHVRHEIEGHIADRLMEALWRE 194
>UniRef50_Q1EVV0 Cluster: Dihydrolipoyl dehydrogenase; n=6;
Clostridium|Rep: Dihydrolipoyl dehydrogenase -
Clostridium oremlandii OhILAs
Length = 467
Score = 43.2 bits (97), Expect = 0.009
Identities = 28/103 (27%), Positives = 55/103 (53%), Gaps = 2/103 (1%)
Frame = +1
Query: 79 GTVASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKY 258
G + S +++ K +++ I+G G+IG +A +F ++G +VTV++ + +DI
Sbjct: 158 GVMTSNELLSFKEIPKRLAIIGGGVIGIEFAGIFNALGSEVTVFEFAPSILIKLDKDISK 217
Query: 259 QLHT-LENDGLLRGELKASEQFQCIKGS-TDLATAVKGAVFVQ 381
+L T L+ DG+ E+ + GS +A KG++ V+
Sbjct: 218 RLTTSLKKDGIKINTSTGVEEIKESNGSLVIVAKDKKGSIEVE 260
>UniRef50_A1WHE6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Verminephrobacter eiseniae EF01-2|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Verminephrobacter eiseniae (strain
EF01-2)
Length = 319
Score = 43.2 bits (97), Expect = 0.009
Identities = 28/108 (25%), Positives = 51/108 (47%)
Frame = +1
Query: 136 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASE 315
++G+G++G + A G V VYD+ + + + + D + E +
Sbjct: 9 VLGAGVLGGQISWHSAFKGKSVVVYDISEEALARCRAAQAHYAAIYQTDAVGASEADVAG 68
Query: 316 QFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
Q + +TDLA+AV A V E VPE +K V+Q + ++ +T+
Sbjct: 69 ARQRLTFATDLASAVASADLVIEAVPEIPQVKTSVYQQMAPLLPAHTL 116
>UniRef50_Q1IIH2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5;
cellular organisms|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Acidobacteria bacterium (strain
Ellin345)
Length = 282
Score = 42.7 bits (96), Expect = 0.012
Identities = 31/114 (27%), Positives = 57/114 (50%), Gaps = 3/114 (2%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQL--HTLEND-GLLRG 297
K+G++G+G +G A +FA GY+V + DV + + + IK L +N +G
Sbjct: 5 KVGVIGAGTMGNGIAHVFAKSGYKVVLCDVKREFLDRGLATIKKNLEREVAKNKISQEQG 64
Query: 298 ELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
++ A + ++ DLA V E E ++K ++F++LDS+ + I
Sbjct: 65 QVAADHIYPTLE-RKDLA----DCDIVVEAASERFEIKAELFRDLDSICRPDVI 113
>UniRef50_Q9AF94 Cluster: 3-hydroxyacyl-CoA-dehydrogenase; n=1;
Acinetobacter sp. DF4|Rep:
3-hydroxyacyl-CoA-dehydrogenase - Acinetobacter sp. DF4
Length = 240
Score = 42.3 bits (95), Expect = 0.016
Identities = 32/119 (26%), Positives = 61/119 (51%), Gaps = 2/119 (1%)
Frame = +1
Query: 109 SKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGL 288
+K+++ K+G++G+G++G A A G V + DV + +A + Y L+ +
Sbjct: 123 TKWQATKVGVLGAGMMGAGIAYSTAIKGIPVVLKDV---SVENAEKGKAYSQKLLDK-RV 178
Query: 289 LRGELKASEQFQCIKGSTDLATA--VKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
+G + A ++ Q + T A+A ++G + E V EN +LK KV Q + + N +
Sbjct: 179 SQGRMTAEKRDQVLSLITATASAQDLQGCDLIIEAVFENQELKAKVTQEAEQYLAPNGV 237
>UniRef50_A4FGV2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Actinomycetales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Saccharopolyspora erythraea (strain NRRL 23338)
Length = 517
Score = 42.3 bits (95), Expect = 0.016
Identities = 26/104 (25%), Positives = 49/104 (47%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
+ ++G+G++GR A L A+ G V + D + ++ A++ + L G + E +A
Sbjct: 11 VRVIGTGVMGRGIAQLAAAAGLTVELADARQEAVSAAVDHVGEMFGKLVGKGRMSAE-EA 69
Query: 310 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSV 441
++ D V E V E+LD K+++F L+ V
Sbjct: 70 DAATARLRPVGDPLAPADSCDLVVEAVREDLDTKRELFAGLEEV 113
>UniRef50_P45856 Cluster: Probable 3-hydroxybutyryl-CoA
dehydrogenase; n=65; Bacteria|Rep: Probable
3-hydroxybutyryl-CoA dehydrogenase - Bacillus subtilis
Length = 287
Score = 42.3 bits (95), Expect = 0.016
Identities = 32/112 (28%), Positives = 52/112 (46%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 303
++I + G+G +G A A G+ V +YDV + ++ +K QL G R E
Sbjct: 4 KQIMVAGAGQMGSGIAQTAADAGFYVRMYDVNPEAAEAGLKRLKKQLARDAEKG-KRTET 62
Query: 304 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
+ I S L A + A V E + EN+ K ++F+ LD + +TI
Sbjct: 63 EVKSVINRISISQTLEEA-EHADIVIEAIAENMAAKTEMFKTLDRICPPHTI 113
>UniRef50_A3YFA8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Marinomonas sp. MED121|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Marinomonas sp. MED121
Length = 545
Score = 41.9 bits (94), Expect = 0.021
Identities = 28/106 (26%), Positives = 52/106 (49%), Gaps = 2/106 (1%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
IG+VG+G +G A + + G++V +YD Q +A K + L N + +G +
Sbjct: 17 IGVVGAGAMGAGIAQVASQAGHKVFLYD----QNEEASFRAKESISLLLNKKVAKGTITR 72
Query: 310 SEQFQCIKGSTDLAT--AVKGAVFVQECVPENLDLKKKVFQNLDSV 441
CI L + +K A + E + E L++K+ +F+ L+ +
Sbjct: 73 EHYDTCIANIIPLHSLDELKSADLIIEAIVETLEIKQSLFRALELI 118
>UniRef50_A5V325 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Sphingomonas wittichii RW1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Sphingomonas wittichii RW1
Length = 322
Score = 41.5 bits (93), Expect = 0.028
Identities = 31/137 (22%), Positives = 53/137 (38%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
+ +G G+IG W F G V ++D + + GL R +
Sbjct: 13 VAAIGGGVIGGGWVAAFLGSGRAVRLHDPAPGAEARIRAHVTQAWPQMAALGLARADDDW 72
Query: 310 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXX 489
+ + + D AV+G FVQE PE D+K+ +F LD +V + +
Sbjct: 73 TGRLSFHETIED---AVEGTDFVQENTPERSDVKRALFAELDRLVPADVLVGSSTSSLPI 129
Query: 490 XXXXEGLKHKSQVIVSH 540
GL ++ ++ H
Sbjct: 130 SDLQAGLSTAARFVLGH 146
Score = 36.3 bits (80), Expect = 1.1
Identities = 21/62 (33%), Positives = 30/62 (48%)
Frame = +2
Query: 548 IHLITYPLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVW 727
+HLI PL E+ T P +G++PV L RE+ G + NR+ A+ E
Sbjct: 151 VHLI--PLVEVGGGDATDPAAVDTALAFYAALGKEPVRLNREVFGHIGNRLTSAMFREAV 208
Query: 728 RL 733
RL
Sbjct: 209 RL 210
>UniRef50_A0HAN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Comamonas testosteroni KF-1
Length = 706
Score = 41.5 bits (93), Expect = 0.028
Identities = 32/111 (28%), Positives = 53/111 (47%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 306
++GI+G+G +G AM FA+ G V + + + + I+ + G L E
Sbjct: 307 RVGILGAGTMGGGIAMAFANAGIPVVLCEREQAALDRGMAMIERNYQISVSRGGLTAE-A 365
Query: 307 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
E+ Q I+ + DL +A V E V E++ +K+ VF LD + TI
Sbjct: 366 VKERMQHIQQTLDL-SAFAEVDLVIEAVFEDMAIKRDVFVQLDRICRKGTI 415
>UniRef50_Q39NP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=54;
cellular organisms|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 284
Score = 41.1 bits (92), Expect = 0.037
Identities = 30/106 (28%), Positives = 50/106 (47%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 303
E +G+VG+G +G A A G V + DV + I +K L L + L
Sbjct: 4 EIVGVVGAGTMGNGIAQTAAVAGLNVVMIDVSDAALEKGIATLKGSLDRLVSKDKLDAAT 63
Query: 304 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSV 441
+ + + I STD A + A V E EN++LK ++ + +++V
Sbjct: 64 RDAALAR-ITTSTDYA-KLAAADIVIEAATENVELKGRILKQIEAV 107
Score = 35.1 bits (77), Expect = 2.4
Identities = 18/54 (33%), Positives = 28/54 (51%)
Frame = +2
Query: 566 PLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVW 727
PL EI+ T A RE+ E + P+ + R GFV+NRI +++E +
Sbjct: 149 PLVEIIRGLQTSDATASAVRELTERFDKSPIGV-RNSPGFVVNRILVPMINEAF 201
>UniRef50_Q1GGC1 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=4; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding -
Silicibacter sp. (strain TM1040)
Length = 733
Score = 41.1 bits (92), Expect = 0.037
Identities = 30/115 (26%), Positives = 60/115 (52%), Gaps = 3/115 (2%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 303
+KIG++G+G++G A++ A G +V + D + DA + K T + G+ RG+
Sbjct: 327 KKIGVLGAGMMGAGIALVSAQAGMEVVLID----RDQDAADKGKAYSATYMDKGIKRGKA 382
Query: 304 ---KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
K I + DL A+KG + E V E+ +K ++ + +++++ ++ I
Sbjct: 383 TPEKKEALLAQITATADL-DALKGCDLIIEAVFEDPGVKAEMTKKVEAIIPEDCI 436
>UniRef50_A1SEZ9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Nocardioides sp. JS614|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 275
Score = 41.1 bits (92), Expect = 0.037
Identities = 33/104 (31%), Positives = 52/104 (50%)
Frame = +1
Query: 121 SEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGE 300
S + +VG G +GR A+ + G++VT+ DV A+ + D + + H + RG
Sbjct: 2 STSMVVVGGGTMGRGIAIAALATGFEVTLVDV-AEDVLDRAQ-ARVSEHFARHPQPDRGV 59
Query: 301 LKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNL 432
L + T LA +++ A V E VPE L LK ++FQ L
Sbjct: 60 LHTT---------TSLAGSLETAEVVIEAVPEILPLKTQIFQQL 94
>UniRef50_A4RUY4 Cluster: Predicted protein; n=5; cellular
organisms|Rep: Predicted protein - Ostreococcus
lucimarinus CCE9901
Length = 722
Score = 41.1 bits (92), Expect = 0.037
Identities = 32/139 (23%), Positives = 60/139 (43%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 303
+ +G+VG GL+G A G QV + ++ + + + I+ L ++ G + E
Sbjct: 305 KSVGVVGGGLMGSGIATACLLAGIQVVLKEIKQEFLDAGVGRIQSNLTSMVRKGRMT-ED 363
Query: 304 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 483
KA + +K T + V E V ENL LK+K+F L+ + + I
Sbjct: 364 KARQLMSLVK-PTLTDQDFRQCDMVIEAVIENLPLKQKIFCELERICKPDCILSTNTSTI 422
Query: 484 XXXXXXEGLKHKSQVIVSH 540
+K+ +++ +H
Sbjct: 423 DITKIAAKMKNPERIVGAH 441
>UniRef50_Q0LRY2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=2; Alphaproteobacteria|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Caulobacter sp. K31
Length = 348
Score = 40.7 bits (91), Expect = 0.049
Identities = 21/83 (25%), Positives = 37/83 (44%)
Frame = +2
Query: 566 PLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLXXXX 745
PL E+VP T + +++ +G++ V + R+I GFV NR+Q+A+ E L
Sbjct: 181 PLVEVVPGIATDAHHVEAMMQLLISVGKKAVRIDRDIPGFVGNRLQFALWREAQSLVANG 240
Query: 746 XXXXXXXXXXMSEGLGXEICIFG 814
+ G + + G
Sbjct: 241 VCDAETLDEIVKSSFGPRLSVLG 263
>UniRef50_A1IFR8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Candidatus
Desulfococcus oleovorans Hxd3
Length = 304
Score = 40.7 bits (91), Expect = 0.049
Identities = 25/101 (24%), Positives = 52/101 (51%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 303
+K+ I+G+G +G+ L A+ G++ +YD+ + A + ++ + L GE
Sbjct: 10 KKVLILGAGSMGQQIGFLCAAKGFETAIYDLSPPLLDTAKKRLEKLAGRFVSRHRLTGE- 68
Query: 304 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQ 426
+A+ + + D A A F+ E V E++++K +VF+
Sbjct: 69 EAAAAMARVTLTPDSEQAAANADFISESVTESVEIKCRVFE 109
Score = 36.3 bits (80), Expect = 1.1
Identities = 16/54 (29%), Positives = 27/54 (50%)
Frame = +2
Query: 557 ITYPLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILD 718
+T + +I+P P T PE A+ R +GQ P+ +E G+ N + + D
Sbjct: 152 LTSDIVDIMPHPGTTPETAETIRAFALRLGQVPIVFKKENHGYAFNALLMNLCD 205
>UniRef50_A0JVH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=12; Actinomycetales|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Arthrobacter sp. (strain FB24)
Length = 723
Score = 40.7 bits (91), Expect = 0.049
Identities = 32/139 (23%), Positives = 61/139 (43%), Gaps = 1/139 (0%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFA-SVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 303
K+G+VG+GL+ A+LFA + V + D+ ++ + + ++ + + +
Sbjct: 350 KVGVVGAGLMASQLALLFARQLKVPVVMTDIDQARVDKGVGYVHAEVDKMLAKKRISAD- 408
Query: 304 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 483
A+ + GS A A FV E V E L++KK+VF ++++V I
Sbjct: 409 AANRTKALVTGSVS-KDAFADADFVIEAVFEELNVKKQVFAEVEAIVSPECILATNTSSL 467
Query: 484 XXXXXXEGLKHKSQVIVSH 540
L H +++ H
Sbjct: 468 SVTAMAADLAHPERLVGFH 486
>UniRef50_A7S4Z9 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 310
Score = 40.7 bits (91), Expect = 0.049
Identities = 32/111 (28%), Positives = 54/111 (48%), Gaps = 1/111 (0%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
+ ++G+GL+G A A G +V +YD A+ A+E K L + + L R E+ A
Sbjct: 8 VAVIGAGLMGTCIAGELAYHGARVNLYDRSAQ----AMEKSKEML-IQQKEQLKREEVMA 62
Query: 310 SEQF-QCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
+ F + L AV + + E ENL++KK VF+++ N +
Sbjct: 63 TSDFIGTVAFCESLEEAVVNSGLIFEATIENLEVKKSVFKSISQFCRTNAV 113
>UniRef50_Q02A28 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Solibacter usitatus Ellin6076|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Solibacter usitatus (strain Ellin6076)
Length = 309
Score = 40.3 bits (90), Expect = 0.065
Identities = 24/89 (26%), Positives = 40/89 (44%)
Frame = +2
Query: 551 HLITYPLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWR 730
HL+ PL EI+ T P A RE++ G+ PV + + G + NR+Q A++ E
Sbjct: 142 HLV--PLVEIIQGRATSPAAAAAVRELLTACGKTPVVVKLDRPGQLGNRLQMALVREAAN 199
Query: 731 LXXXXXXXXXXXXXXMSEGLGXEICIFGV 817
+ + GLG + +G+
Sbjct: 200 IVAEGIADAEAVDSVVKNGLGIRMPAYGI 228
Score = 33.1 bits (72), Expect = 9.8
Identities = 27/102 (26%), Positives = 48/102 (47%)
Frame = +1
Query: 136 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKASE 315
++G+G++G A+ A G Q T+ + + + +L + L+ EL A+
Sbjct: 8 VIGTGMMGPGIALTLALGGVQTTLLSRTPAGAERGVAEAR-RLGRV----LVEQELAAAL 62
Query: 316 QFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSV 441
I GSTD ++ A V E PE + K+++F +D V
Sbjct: 63 DLD-IAGSTDFEYSIGQADIVIESGPEEMGWKQELFARMDRV 103
>UniRef50_A6GC68 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 733
Score = 40.3 bits (90), Expect = 0.065
Identities = 33/120 (27%), Positives = 57/120 (47%), Gaps = 8/120 (6%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHT----LENDG-- 285
E++ I+G+G++G A + A GYQV + D+ + + + + QL L++ G
Sbjct: 333 ERVAILGAGMMGAGLAYICADAGYQVVLKDINQEALDKGVAHFEAQLRKRKRHLDDAGRQ 392
Query: 286 LLRGELKASEQFQCI--KGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
+R L S + + G TDL + E V ENLDLK +V + + + + I
Sbjct: 393 AIRDRLTPSLELSALSDNGGTDL---------IIEAVFENLDLKHRVTRETEPTLSADGI 443
>UniRef50_A0JTB4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 333
Score = 40.3 bits (90), Expect = 0.065
Identities = 19/56 (33%), Positives = 32/56 (57%)
Frame = +2
Query: 566 PLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRL 733
P EI+P T R+++ G+Q ++ +++ GFVLNR+QYA+ E +L
Sbjct: 166 PGVEIIPHAGTSATTVGAVRDLVHAAGKQ-TAVVKDVTGFVLNRLQYALFHEAAQL 220
>UniRef50_UPI00015BAF7B Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Ignicoccus hospitalis KIN4/I|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Ignicoccus hospitalis KIN4/I
Length = 683
Score = 39.9 bits (89), Expect = 0.086
Identities = 17/51 (33%), Positives = 31/51 (60%)
Frame = +2
Query: 569 LXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDE 721
L E+V T E K T E+ +++G+ P+ + +++ GF++NRI L+E
Sbjct: 177 LVEVVRGKETSDETVKITVELAKKMGKVPIVVNKDVPGFIVNRIMARFLNE 227
>UniRef50_A4SW27 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7;
Burkholderiales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 313
Score = 39.9 bits (89), Expect = 0.086
Identities = 19/61 (31%), Positives = 33/61 (54%)
Frame = +2
Query: 551 HLITYPLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWR 730
HL+ P E+V T P V +M G PV++ +++ GF+ NR+Q+A+ E +
Sbjct: 143 HLV--PCVEVVYGEKTSPMVGDSLSRLMTACGMVPVTVKKDLPGFLANRLQHALSREAFA 200
Query: 731 L 733
+
Sbjct: 201 M 201
>UniRef50_A0IJE2 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=5; Gammaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Serratia proteamaculans 568
Length = 506
Score = 39.9 bits (89), Expect = 0.086
Identities = 23/111 (20%), Positives = 53/111 (47%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 306
++ ++G+G +G A + A+ G+QV ++D+ A A+ + +L G + +
Sbjct: 9 RVAVIGAGTMGIGIAQVAAAAGHQVQLFDIAASAARQALGALAQRLRQRVAAG--KADAT 66
Query: 307 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
+E + ++ + V E V E L +K+ +F+ L+++ T+
Sbjct: 67 TTEALLARIQPAESLNSLADSGLVIEAVAEKLAIKQSLFRELEALCSPATL 117
>UniRef50_P45364 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=13;
Clostridia|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Clostridium difficile
Length = 281
Score = 39.9 bits (89), Expect = 0.086
Identities = 33/138 (23%), Positives = 55/138 (39%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 306
K+ ++GSG +G FAS G+ V + I + + L L G K
Sbjct: 2 KLAVIGSGTMGSGIVQTFASCGHDVCLKSRTQGAIDKCLALLDKNLTKLVTKGKWMKATK 61
Query: 307 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 486
A E + +T+ +K + E E++++KK VF+ LD + ++TI
Sbjct: 62 A-EILSHVSSTTNYED-LKDMDLIIEASVEDMNIKKDVFKLLDELCKEDTILATNTSSLS 119
Query: 487 XXXXXEGLKHKSQVIVSH 540
K +VI H
Sbjct: 120 ITEIASSTKRPDKVIGMH 137
>UniRef50_Q88X11 Cluster: NADH peroxidase; n=1; Lactobacillus
plantarum|Rep: NADH peroxidase - Lactobacillus plantarum
Length = 438
Score = 39.5 bits (88), Expect = 0.11
Identities = 29/83 (34%), Positives = 47/83 (56%), Gaps = 3/83 (3%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQL---HTLENDGLLR 294
+ + ++G G IG ++A LF G QVTV DV A+ + ++ Q+ ++EN GL
Sbjct: 137 KNVVVIGGGYIGMNFAALFKQTGKQVTVIDVNARPFSHNLDSEFTQILAAASVEN-GL-- 193
Query: 295 GELKASEQFQCIKGSTDLATAVK 363
+LK E+ + GST + TAV+
Sbjct: 194 -QLKMEERVTAVLGSTHV-TAVQ 214
>UniRef50_Q1YHC5 Cluster: Putative 3-hydroxybutyryl-CoA
dehydrogenase; n=1; Aurantimonas sp. SI85-9A1|Rep:
Putative 3-hydroxybutyryl-CoA dehydrogenase -
Aurantimonas sp. SI85-9A1
Length = 286
Score = 39.5 bits (88), Expect = 0.11
Identities = 23/90 (25%), Positives = 38/90 (42%)
Frame = +2
Query: 566 PLXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLXXXX 745
P+ E V T P ++ G + + R + G V+NR+Q+AIL E + L
Sbjct: 123 PMVESVRVAETAPATVDTALALLRAAGWDSIVVPRPVPGAVVNRLQHAILHEAYHLMAEG 182
Query: 746 XXXXXXXXXXMSEGLGXEICIFGVLXKQPI 835
LG +CI G+L ++ +
Sbjct: 183 LASVEDIDRAARWLLGPRMCIAGLLKQKDL 212
>UniRef50_A3ZYI9 Cluster: Fatty oxidation complex, alpha subunit
FadB; n=1; Blastopirellula marina DSM 3645|Rep: Fatty
oxidation complex, alpha subunit FadB - Blastopirellula
marina DSM 3645
Length = 724
Score = 39.5 bits (88), Expect = 0.11
Identities = 27/116 (23%), Positives = 53/116 (45%)
Frame = +1
Query: 112 KFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLL 291
K K E + ++G+G++G A G T+ D A+ + + + + + D
Sbjct: 314 KTKIESVSVIGAGIMGAGIAAASIRRGILTTLSDANAEALRRGVAGVLEEA-AYDRDAGK 372
Query: 292 RGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
+ KA E + S + V + V E + ENL++K+K++ L+ + D+ I
Sbjct: 373 KTIAKAVEGAAMLNASIS-DSEVAASKLVIEAIVENLEVKRKIYARLEPQLADDAI 427
>UniRef50_A1SQH4 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=104; cellular organisms|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 736
Score = 39.5 bits (88), Expect = 0.11
Identities = 32/118 (27%), Positives = 57/118 (48%), Gaps = 3/118 (2%)
Frame = +1
Query: 115 FKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLR 294
+++ K+G++G+G++G A A G +V + DV ++ E K L + + +
Sbjct: 322 YRAVKVGVLGAGMMGAGIAYSCARSGMEVVLKDVA----VESAEKGKAYSEKLLDKAIAK 377
Query: 295 G---ELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
G E K +E I + D A + G V E V E+ LK++VF + VD + +
Sbjct: 378 GRSTEEKKAELLGRITATAD-AADLAGCDLVIEAVFEDPSLKQQVFAEIAPYVDQDAL 434
>UniRef50_Q6MHW5 Cluster: Glucose-inhibited division protein; n=1;
Bdellovibrio bacteriovorus|Rep: Glucose-inhibited
division protein - Bdellovibrio bacteriovorus
Length = 440
Score = 39.1 bits (87), Expect = 0.15
Identities = 23/74 (31%), Positives = 38/74 (51%)
Frame = +1
Query: 103 MASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLEND 282
M + +++KI +VG+GL G A+ A +GY V +Y++ K +T A + K+ N
Sbjct: 1 MTNITQNQKITVVGAGLAGSECALQLADMGYSVVLYEMRDKTMTPAHKTHKFAELVCSNS 60
Query: 283 GLLRGELKASEQFQ 324
GE A Q +
Sbjct: 61 FGSLGEHSAPGQLK 74
>UniRef50_Q5LVG3 Cluster: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase;
n=2; Rhodobacteraceae|Rep: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase -
Silicibacter pomeroyi
Length = 681
Score = 39.1 bits (87), Expect = 0.15
Identities = 33/113 (29%), Positives = 53/113 (46%), Gaps = 2/113 (1%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 306
++ IVG GL+G AM G VTV + A A + + ++ L G+ RG++
Sbjct: 288 RVAIVGGGLMGAGVAMACLGGGLSVTVIERDAA----AAQAAQERVAGLVAAGVKRGKIS 343
Query: 307 ASEQFQCIK--GSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
Q + +TD A E V E+LD+K+ VF +L +V+ + I
Sbjct: 344 PDAQADMLARLATTDTYADASDADLAIEAVFEDLDVKRIVFADLAAVMRPDAI 396
>UniRef50_Q5LVD0 Cluster: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase;
n=6; Rhodobacterales|Rep: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase -
Silicibacter pomeroyi
Length = 698
Score = 39.1 bits (87), Expect = 0.15
Identities = 32/107 (29%), Positives = 52/107 (48%), Gaps = 3/107 (2%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
IG++G G +G A G VT+ ++ +A E K ++ + L RG+L A
Sbjct: 292 IGVIGGGTMGAGIATAALLSGLSVTMLEMT----PEAAEAAKGRIEGNLSGALKRGKLTA 347
Query: 310 SEQFQCIKGSTDLA---TAVKGAVFVQECVPENLDLKKKVFQNLDSV 441
+ + LA A+ A V E V E++++KK+VF LD+V
Sbjct: 348 QQFDNLTTKALTLAIDYDALADADLVIEAVFEDMEVKKQVFTKLDAV 394
>UniRef50_Q4Q939 Cluster: Trifunctional enzyme alpha subunit,
mitochondrial-like protein; n=6; Trypanosomatidae|Rep:
Trifunctional enzyme alpha subunit, mitochondrial-like
protein - Leishmania major
Length = 726
Score = 39.1 bits (87), Expect = 0.15
Identities = 24/104 (23%), Positives = 48/104 (46%), Gaps = 1/104 (0%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQL-HTLENDGLLRGEL 303
++G++G+G++G FA V V D+ + + I +++ + + ++ EL
Sbjct: 309 RVGVIGAGVMGSGIVHYFAKNNIPVAVKDLTEESVKQGITNVRAEFERAVRRKRMVTAEL 368
Query: 304 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLD 435
+ + G T + A + E E +D+KKKV Q L+
Sbjct: 369 DG--KMALVTGGT-TNEVFRDADVIVEAAVEVMDIKKKVIQQLE 409
>UniRef50_O29090 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 312
Score = 39.1 bits (87), Expect = 0.15
Identities = 30/105 (28%), Positives = 56/105 (53%), Gaps = 1/105 (0%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQ-LHTLENDGLLRGELK 306
I ++G+G +G + A+LFA+ G++VT+ D + A + + + L LE GL + +
Sbjct: 5 IAVIGAGTMGAAIALLFANAGFEVTLVDKSRGALRRAEDRHRGESLEELEEAGLRKQDNP 64
Query: 307 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSV 441
AS I +T+L V F+ E + E L K ++F+ ++ +
Sbjct: 65 AS----LITYTTEL--RVYECDFIVEAIVERLRDKIELFRKIEEI 103
>UniRef50_Q8RC01 Cluster: UDP-N-acetyl-D-mannosaminuronate
dehydrogenase; n=18; Bacteria|Rep:
UDP-N-acetyl-D-mannosaminuronate dehydrogenase -
Thermoanaerobacter tengcongensis
Length = 445
Score = 38.7 bits (86), Expect = 0.20
Identities = 31/107 (28%), Positives = 50/107 (46%), Gaps = 2/107 (1%)
Frame = +1
Query: 103 MASKFKSEK--IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLE 276
+ K +S+K IG++G G +G A+ A GY+V +D+ ++ I Y
Sbjct: 14 LLDKIESKKAVIGVIGLGYVGLPLAVEKAKAGYKVIGFDIQKHKVEKVNNGINY------ 67
Query: 277 NDGLLRGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKK 417
+L G+LK + +K + D A +K V CVP LD K+
Sbjct: 68 IGDILDGDLKEVVEQGRLKATNDYA-FLKDVDAVAICVPTPLDKNKQ 113
>UniRef50_Q39TJ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like; n=1;
Geobacter metallireducens GS-15|Rep: 3-hydroxyacyl-CoA
dehydrogenase-like - Geobacter metallireducens (strain
GS-15 / ATCC 53774 / DSM 7210)
Length = 290
Score = 38.7 bits (86), Expect = 0.20
Identities = 27/112 (24%), Positives = 49/112 (43%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 303
+K+ I+G+G++G A+ A GY V + +V +E I+ L G L +
Sbjct: 5 KKVAILGAGMMGSDIALSCALAGYDVLLKEVSLDLAAAGVERIRGSLAKWSEKGRLAVDA 64
Query: 304 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
+ + D + V E + E+LD+K + F+ L+ V + I
Sbjct: 65 EQQKSAVARITPVDNFSGFGDVDLVIEAIFEDLDVKSQNFRQLEEVCKPSCI 116
Score = 33.9 bits (74), Expect = 5.6
Identities = 24/84 (28%), Positives = 35/84 (41%)
Frame = +2
Query: 569 LXEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLXXXXX 748
L E+V T E + IG++P+ + + GFV+NRI AI DE RL
Sbjct: 156 LVEVVNGEDTSAETVETACAFCTSIGKEPIKVN-DCAGFVVNRILGAINDEAIRLLEENV 214
Query: 749 XXXXXXXXXMSEGLGXEICIFGVL 820
GLG + F ++
Sbjct: 215 ASAADIDKACQLGLGHPVGPFALM 238
>UniRef50_Q0C0V2 Cluster: Oxidoreductase, FAD-binding; n=2;
Proteobacteria|Rep: Oxidoreductase, FAD-binding -
Hyphomonas neptunium (strain ATCC 15444)
Length = 377
Score = 38.7 bits (86), Expect = 0.20
Identities = 21/59 (35%), Positives = 33/59 (55%), Gaps = 1/59 (1%)
Frame = +1
Query: 70 LSCGTVASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVY-DVVAKQITDAI 243
LS GT +MA + + + I+G G++G + A++ A G+ VTVY DV+ T I
Sbjct: 87 LSWGTCQRAAVMAGETGRQDVAILGGGVMGLTSALILARRGHDVTVYADVMHPNTTSNI 145
>UniRef50_A3D4X7 Cluster: FAD dependent oxidoreductase; n=3;
Shewanella baltica|Rep: FAD dependent oxidoreductase -
Shewanella baltica OS155
Length = 578
Score = 38.3 bits (85), Expect = 0.26
Identities = 18/45 (40%), Positives = 29/45 (64%)
Frame = +1
Query: 88 ASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVA 222
A+ +++ S KS+ + I G G+ G + A FA +GYQV V++V A
Sbjct: 13 ATELLIKSSTKSKSVAIFGGGIAGLTAAHEFAKLGYQVKVFEVNA 57
>UniRef50_Q8G3X6 Cluster: Possible class I pyridine
nucleotide-disulfideoxidoreductase; n=2; Bifidobacterium
longum|Rep: Possible class I pyridine
nucleotide-disulfideoxidoreductase - Bifidobacterium
longum
Length = 544
Score = 37.9 bits (84), Expect = 0.35
Identities = 30/100 (30%), Positives = 44/100 (44%), Gaps = 4/100 (4%)
Frame = +1
Query: 79 GTVASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVY----DVVAKQITDAIE 246
G ST +M +++ I+GSG IG +A +FA G VTV + + ++ D
Sbjct: 173 GVYTSTGLMDLDDMPQRLVIIGSGFIGLEFASMFADFGTAVTVLQHNAEFLPREDADVAA 232
Query: 247 DIKYQLHTLENDGLLRGELKASEQFQCIKGSTDLATAVKG 366
I+ QL L + KA G L+ AVKG
Sbjct: 233 AIRAQLEAQGVKFLFNADTKAIA--PAADGGVRLSVAVKG 270
>UniRef50_Q8FRT3 Cluster: Putative 3-hydroxybutyryl-CoA
dehydrogenase; n=2; Corynebacterineae|Rep: Putative
3-hydroxybutyryl-CoA dehydrogenase - Corynebacterium
efficiens
Length = 294
Score = 37.9 bits (84), Expect = 0.35
Identities = 32/102 (31%), Positives = 46/102 (45%), Gaps = 1/102 (0%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
+G++G G +G A F + G VTV D+ + A E I + + RG
Sbjct: 23 VGVLGGGRMGAGIAHSFLAAGAHVTVVDINDAAVEAARERITNDI----EGSIKRGAEGT 78
Query: 310 SEQF-QCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNL 432
EQ+ + STD A V V E VPE +DLK F+ +
Sbjct: 79 VEQWLDRLTLSTDTAAFADHPVVV-EAVPEIIDLKADSFRKI 119
>UniRef50_Q1ATL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Rubrobacter xylanophilus DSM 9941|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 287
Score = 37.9 bits (84), Expect = 0.35
Identities = 19/73 (26%), Positives = 32/73 (43%)
Frame = +2
Query: 575 EIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLXXXXXXX 754
E+V T E ++ R ++ G+ PV + +++ GF NR+ +L E RL
Sbjct: 151 EVVRGEQTSDETVERVRRLLSSFGKLPVVVRKDVPGFAANRLLMPVLLEAARLVEEGVAS 210
Query: 755 XXXXXXXMSEGLG 793
+ GLG
Sbjct: 211 REEVDLLATRGLG 223
Score = 37.5 bits (83), Expect = 0.46
Identities = 25/110 (22%), Positives = 52/110 (47%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
+G++G+G +G + A GY+V D + + A ++ L + G L E +A
Sbjct: 5 VGVLGTGTMGAGIVQVAARAGYRVVACDASEEALGKARRYVRSGLESFARRGAL-SEEEA 63
Query: 310 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
++ +T + + G+ V E + E + KK+ F LD+++ + +
Sbjct: 64 EAALGRVRWTTAM-EELAGSEAVIEAIVERVGPKKEAFAALDALLPPDAL 112
>UniRef50_P14218 Cluster: Dihydrolipoyl dehydrogenase; n=65;
cellular organisms|Rep: Dihydrolipoyl dehydrogenase -
Pseudomonas fluorescens
Length = 478
Score = 37.9 bits (84), Expect = 0.35
Identities = 23/69 (33%), Positives = 38/69 (55%), Gaps = 1/69 (1%)
Frame = +1
Query: 85 VASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDI-KYQ 261
V ST + + +K+G++G+G+IG ++A +G +VTV + + K + A E I K
Sbjct: 169 VDSTGALEFQAVPKKLGVIGAGVIGLELGSVWARLGAEVTVLEALDKFLPAADEQIAKEA 228
Query: 262 LHTLENDGL 288
L L GL
Sbjct: 229 LKVLTKQGL 237
>UniRef50_Q8YB80 Cluster: 3-HYDROXYBUTYRYL-COA DEHYDROGENASE; n=32;
Proteobacteria|Rep: 3-HYDROXYBUTYRYL-COA DEHYDROGENASE -
Brucella melitensis
Length = 565
Score = 37.5 bits (83), Expect = 0.46
Identities = 29/112 (25%), Positives = 48/112 (42%), Gaps = 2/112 (1%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGE--L 303
I IVG+G++G A + A G ++D +++ + L L G + E
Sbjct: 48 IAIVGAGVMGTGIAQIAAQAGLVTQIFDAREGAAAASLDRLASTLAKLAEKGKISAEDAQ 107
Query: 304 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
A + + +LA V E + E LD K+ +F L++VV N I
Sbjct: 108 TAVSRIEICSSIQELA----DCDLVVEAIVEKLDAKQALFLELEAVVSGNCI 155
>UniRef50_Q8CXB6 Cluster: UDP-glucose:GDP-mannose dehydrogenase;
n=2; Bacillaceae|Rep: UDP-glucose:GDP-mannose
dehydrogenase - Oceanobacillus iheyensis
Length = 440
Score = 37.5 bits (83), Expect = 0.46
Identities = 15/40 (37%), Positives = 25/40 (62%)
Frame = +1
Query: 115 FKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQIT 234
+ + K+G++G G +G A+LF GYQVT D+ +I+
Sbjct: 12 YVNSKVGVIGMGYVGLPLALLFLKKGYQVTGIDINQSKIS 51
>UniRef50_Q88YA7 Cluster: Bifunctional protein: amino acid
aminotransferase; 2-hydroxyacid dehydrogenase; n=2;
Lactobacillus|Rep: Bifunctional protein: amino acid
aminotransferase; 2-hydroxyacid dehydrogenase -
Lactobacillus plantarum
Length = 543
Score = 37.5 bits (83), Expect = 0.46
Identities = 21/60 (35%), Positives = 34/60 (56%)
Frame = +1
Query: 100 IMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLEN 279
+ A + +S +GI+G+G IG + A LF +G +V YDVV +ED+ + T E+
Sbjct: 352 LQAREIRSLTVGIIGAGRIGGTAARLFHGLGAKVIAYDVVRH---PELEDVLTYVDTKED 408
>UniRef50_Q4A6P9 Cluster: Putative mercuric reductase; n=1;
Mycoplasma synoviae 53|Rep: Putative mercuric reductase
- Mycoplasma synoviae (strain 53)
Length = 459
Score = 37.5 bits (83), Expect = 0.46
Identities = 25/81 (30%), Positives = 42/81 (51%), Gaps = 1/81 (1%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQI-TDAIEDIKYQLHTLENDGLLRGE 300
+K+ +VG+G IG +A FA+ G QVTV + + ED K+ L TL+ G+
Sbjct: 177 KKLLVVGAGFIGLEFASYFANFGTQVTVAQYNNDFMPNEDKEDSKFILDTLKKQGIKFEF 236
Query: 301 LKASEQFQCIKGSTDLATAVK 363
E+F+ +K ++ + K
Sbjct: 237 NTTCEKFKDLKSQVQVSLSNK 257
>UniRef50_Q0SUA0 Cluster: Pyridine nucleotide-disulphide
oxidoreductase; n=9; Bacteria|Rep: Pyridine
nucleotide-disulphide oxidoreductase - Clostridium
perfringens (strain SM101 / Type A)
Length = 457
Score = 37.5 bits (83), Expect = 0.46
Identities = 26/80 (32%), Positives = 42/80 (52%), Gaps = 4/80 (5%)
Frame = +1
Query: 91 STVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYD----VVAKQITDAIEDIKY 258
ST IM K + + IVG G IG +A ++AS G +VTV + + ++ D + IK
Sbjct: 160 STTIMELKELPKHLVIVGGGYIGLEFASIYASFGSKVTVIEAFDRIAGREDEDISKSIKE 219
Query: 259 QLHTLENDGLLRGELKASEQ 318
L + LL ++K+ E+
Sbjct: 220 ILEKKGIEFLLGSKVKSFEE 239
>UniRef50_A0J682 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Shewanella woodyi ATCC 51908|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Shewanella woodyi ATCC 51908
Length = 696
Score = 37.5 bits (83), Expect = 0.46
Identities = 26/110 (23%), Positives = 52/110 (47%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
+G+VG+G +G A F G + + + + +++++ + G + E
Sbjct: 308 VGVVGAGNMGVGIARCFIDAGMDLIWIEQTEEALLRGMDNLRKGYQSKITKGHMT-EQDL 366
Query: 310 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
++ Q +KGST + + V E E+L++KK +F+ LD D+ I
Sbjct: 367 DDKMQLVKGST-VYDRLAPCDLVVEAAFEDLEVKKIIFKALDQHCKDSAI 415
>UniRef50_Q45223 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=92;
cellular organisms|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Bradyrhizobium japonicum
Length = 293
Score = 37.5 bits (83), Expect = 0.46
Identities = 25/112 (22%), Positives = 51/112 (45%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 303
+K+G++G+G +G A + A G+ V + DV A ++ + I L + ++ E
Sbjct: 6 KKVGVIGAGQMGNGIAHVAALAGFDVVLNDVSADRLKSGMATINGNLARQVSKKVVTEEA 65
Query: 304 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
K + + + + + V E E ++K+K+F L +V+ I
Sbjct: 66 KTKALSRIV--AAEKLDDLADCDLVIETAVEKEEVKRKIFHELCAVLKPEAI 115
>UniRef50_O34324 Cluster: Dihydrolipoyl dehydrogenase; n=13;
Bacillus|Rep: Dihydrolipoyl dehydrogenase - Bacillus
subtilis
Length = 458
Score = 37.5 bits (83), Expect = 0.46
Identities = 22/52 (42%), Positives = 30/52 (57%), Gaps = 1/52 (1%)
Frame = +1
Query: 136 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDI-KYQLHTLENDGL 288
IVG G+IG +A LFA +G QVT+ + + I EDI + LE DG+
Sbjct: 175 IVGGGVIGCEYAGLFARLGSQVTIIETADRLIPAEDEDIARLFQEKLEEDGV 226
>UniRef50_P38169 Cluster: Kynurenine 3-monooxygenase; n=4;
Saccharomycetales|Rep: Kynurenine 3-monooxygenase -
Saccharomyces cerevisiae (Baker's yeast)
Length = 460
Score = 37.5 bits (83), Expect = 0.46
Identities = 15/31 (48%), Positives = 22/31 (70%)
Frame = +1
Query: 121 SEKIGIVGSGLIGRSWAMLFASVGYQVTVYD 213
SE + I+G+GL+G A+ F+ GY VT+YD
Sbjct: 2 SESVAIIGAGLVGCLAALAFSKEGYNVTLYD 32
>UniRef50_Q82W31 Cluster: Phosphoribosylaminoimidazole carboxylase,
ATPase subunit; ATP-grasp domain; n=2;
Proteobacteria|Rep: Phosphoribosylaminoimidazole
carboxylase, ATPase subunit; ATP-grasp domain -
Nitrosomonas europaea
Length = 376
Score = 37.1 bits (82), Expect = 0.60
Identities = 18/53 (33%), Positives = 29/53 (54%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGL 288
+G++G G +GR +AM +GY+VTV D A+ +I + Q L + L
Sbjct: 9 LGLLGGGQLGRMFAMAAQQMGYRVTVLDPAAESPAGSIAERHLQADYLNDQAL 61
>UniRef50_Q1FP37 Cluster: NADH:flavin oxidoreductase/NADH
oxidase:FAD-dependent pyridine nucleotide-disulphide
oxidoreductase:Acetoacetate decarboxylase; n=1;
Clostridium phytofermentans ISDg|Rep: NADH:flavin
oxidoreductase/NADH oxidase:FAD-dependent pyridine
nucleotide-disulphide oxidoreductase:Acetoacetate
decarboxylase - Clostridium phytofermentans ISDg
Length = 937
Score = 37.1 bits (82), Expect = 0.60
Identities = 19/53 (35%), Positives = 28/53 (52%)
Frame = +1
Query: 82 TVASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDA 240
TV S + S K EK+ ++G+GL G A G QVT+ D++ K +A
Sbjct: 503 TVESVLSGKSALKGEKVAVIGAGLTGLETAEYLFEEGNQVTIIDMLDKPAPNA 555
>UniRef50_A6P2M7 Cluster: Putative uncharacterized protein; n=2;
Bacteria|Rep: Putative uncharacterized protein -
Bacteroides capillosus ATCC 29799
Length = 321
Score = 37.1 bits (82), Expect = 0.60
Identities = 16/63 (25%), Positives = 29/63 (46%)
Frame = +1
Query: 61 TRGLSCGTVASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDA 240
T L C T+ + + + + KI +G G++G+S GY +T+Y + D
Sbjct: 15 TAPLPCFTIKAAGMRKERIEMNKIAFIGVGIMGKSMVRNLMKAGYSLTIYSRTKAKCEDV 74
Query: 241 IED 249
I +
Sbjct: 75 IAE 77
>UniRef50_A5WEP3 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=7; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Psychrobacter sp. PRwf-1
Length = 723
Score = 37.1 bits (82), Expect = 0.60
Identities = 33/144 (22%), Positives = 60/144 (41%), Gaps = 3/144 (2%)
Frame = +1
Query: 118 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG 297
K K+GI+G+G++G A + A G V + D +A E K L + + RG
Sbjct: 321 KVSKVGILGAGMMGAGIAYVSAKAGIDVVLLDT----SIEAAEKGKDYSSKLLDKAIARG 376
Query: 298 ELKASEQFQCIKGSTDLATA---VKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXX 468
++ Q + + TA ++ + E V E++D+K +N ++V+ + I
Sbjct: 377 R-STEQKKQALLDKINTTTAYDDLEDCDLIIEAVFEDIDIKAACTRNTEAVIAETAIYAS 435
Query: 469 XXXXXXXXXXXEGLKHKSQVIVSH 540
+ K +Q I H
Sbjct: 436 NTSTLPITELAKASKRPNQFIGLH 459
>UniRef50_A4XMY3 Cluster: Prephenate dehydrogenase; n=1;
Caldicellulosiruptor saccharolyticus DSM 8903|Rep:
Prephenate dehydrogenase - Caldicellulosiruptor
saccharolyticus (strain ATCC 43494 / DSM 8903)
Length = 290
Score = 37.1 bits (82), Expect = 0.60
Identities = 20/53 (37%), Positives = 31/53 (58%), Gaps = 2/53 (3%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIED--IKYQLHTLEN 279
KI +VG GLIG S A F G++V +D+ + AIE+ +K ++ LE+
Sbjct: 15 KILVVGLGLIGGSLAKAFHKCGFEVHAHDINQNSVEKAIEEGIVKEKIEDLED 67
>UniRef50_A4WWF6 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=5; Rhodobacteraceae|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Rhodobacter sphaeroides ATCC 17025
Length = 673
Score = 37.1 bits (82), Expect = 0.60
Identities = 29/138 (21%), Positives = 57/138 (41%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 306
+IG++G G +G A A+ G + T+ + + I+ ++ G L
Sbjct: 292 RIGVIGGGTMGSGIAAAIAAAGLEATLAETGPDALEAGIKRVRAIFEAQVTRG-LTDRAG 350
Query: 307 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX 486
A+++ + G+ L + V E V E+L +K++VF++L + + I
Sbjct: 351 AADRLARVSGTVGLG-PLADCDLVIEAVFEDLAVKRRVFEDLTRLCRPDAILATNTSYLD 409
Query: 487 XXXXXEGLKHKSQVIVSH 540
GL + + I H
Sbjct: 410 PERIVAGLPNPDRFIALH 427
>UniRef50_Q6D2L7 Cluster: Fatty acid oxidation complex subunit alpha
[Includes: Enoyl-CoA hydratase/3-hydroxybutyryl-CoA
epimerase (EC 4.2.1.17) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)]; n=16;
Gammaproteobacteria|Rep: Fatty acid oxidation complex
subunit alpha [Includes: Enoyl-CoA
hydratase/3-hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.1.2.3); 3-hydroxyacyl-CoA dehydrogenase (EC
1.1.1.35)] - Erwinia carotovora subsp. atroseptica
(Pectobacterium atrosepticum)
Length = 731
Score = 37.1 bits (82), Expect = 0.60
Identities = 35/139 (25%), Positives = 58/139 (41%), Gaps = 1/139 (0%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVG-YQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 303
++GI+G GL+G A + A+ G V + D+ + I A++ +QL T
Sbjct: 324 RVGILGGGLMGGGIASVTATRGQLPVRIKDINEQGINHALK-YNWQLLTKRVQSKRMKPT 382
Query: 304 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 483
+ I GSTD + A V E V E+L LK+++ ++ +TI
Sbjct: 383 ERQRLMTLISGSTDY-RGFEHADIVIEAVFEDLALKRQMITEIEDHAAPHTIFASNTSSL 441
Query: 484 XXXXXXEGLKHKSQVIVSH 540
EG + V+ H
Sbjct: 442 PIHQIAEGARRPQLVVGLH 460
>UniRef50_UPI000018F68E Cluster: hypothetical protein Rm378p142;
n=1; Rhodothermus phage RM378|Rep: hypothetical protein
Rm378p142 - Bacteriophage RM 378
Length = 282
Score = 36.7 bits (81), Expect = 0.80
Identities = 18/68 (26%), Positives = 34/68 (50%)
Frame = +1
Query: 244 EDIKYQLHTLENDGLLRGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVF 423
EDIK + ++ DG L E++ + D+ +KGAV +E V E +DL +
Sbjct: 130 EDIKIDVEDVDEDGELEAEIELKDADLSDDEELDIDVDIKGAVESEEHVREEMDLLHTLL 189
Query: 424 QNLDSVVD 447
+ ++ ++
Sbjct: 190 ERVEEAIE 197
>UniRef50_Q9X0U4 Cluster: Glutamate synthase, beta subunit; n=5;
Bacteria|Rep: Glutamate synthase, beta subunit -
Thermotoga maritima
Length = 618
Score = 36.7 bits (81), Expect = 0.80
Identities = 15/36 (41%), Positives = 24/36 (66%)
Frame = +1
Query: 118 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAK 225
K + +GI+GSG G + A A++GY VT+Y+ +K
Sbjct: 295 KGKSVGIIGSGPAGLAAAYFLATMGYDVTIYESESK 330
>UniRef50_Q8CX86 Cluster: UDP-glucose:GDP-mannose dehydrogenase;
n=16; Bacteria|Rep: UDP-glucose:GDP-mannose
dehydrogenase - Oceanobacillus iheyensis
Length = 448
Score = 36.7 bits (81), Expect = 0.80
Identities = 27/100 (27%), Positives = 51/100 (51%)
Frame = +1
Query: 118 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG 297
KS +G+VG G +G A+ A GY+V +DV ++I + I Y + + ++ L+
Sbjct: 23 KSATLGVVGLGYVGLPLAVEKAKAGYKVIGFDVQLEKIEKLAQGINY-IGDVNDEELI-- 79
Query: 298 ELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKK 417
++ ++F +T+ + + V CVP LD+ K+
Sbjct: 80 QVINKDKFY----ATNDYSLINNVDVVVICVPTPLDIHKQ 115
>UniRef50_Q9N5G1 Cluster: Dehydrogenases, short chain protein 15;
n=4; Caenorhabditis|Rep: Dehydrogenases, short chain
protein 15 - Caenorhabditis elegans
Length = 278
Score = 36.7 bits (81), Expect = 0.80
Identities = 25/76 (32%), Positives = 43/76 (56%), Gaps = 3/76 (3%)
Frame = +1
Query: 121 SEKIGIV--GSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLR 294
S+K+ I+ S IGRS A+L A G +VTV +++I + + +I + +N ++
Sbjct: 5 SDKVAIITGSSSGIGRSTAVLLAQEGAKVTVTGRSSEKIQETVNEIHKNGGSSDNINIVL 64
Query: 295 GELKASE-QFQCIKGS 339
G+L SE Q + IK +
Sbjct: 65 GDLNESECQDELIKST 80
>UniRef50_Q0UJN7 Cluster: Predicted protein; n=1; Phaeosphaeria
nodorum|Rep: Predicted protein - Phaeosphaeria nodorum
(Septoria nodorum)
Length = 152
Score = 36.7 bits (81), Expect = 0.80
Identities = 33/139 (23%), Positives = 57/139 (41%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 303
+ +GIVG+G+IG SW LF + G +V V D + +K TL++ G +
Sbjct: 4 QTVGIVGTGVIGASWTGLFLAHGLRVLVADPAPGAKEKLEKHLKAIWPTLQSIGTKKSAS 63
Query: 304 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXX 483
A+ F A G + ++ PE +LK+ + +DS V + +
Sbjct: 64 LANYTF---------VGASLGQHY-KKNAPERQNLKQSLLAEIDSSVRSDVVIASSSSGI 113
Query: 484 XXXXXXEGLKHKSQVIVSH 540
K +V++ H
Sbjct: 114 PSSRFISKCKTPERVLIGH 132
>UniRef50_Q89SH2 Cluster: Blr2428 protein; n=7; Rhizobiales|Rep:
Blr2428 protein - Bradyrhizobium japonicum
Length = 715
Score = 36.3 bits (80), Expect = 1.1
Identities = 27/102 (26%), Positives = 51/102 (50%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
+ ++G+G +G A A G +V++ D+ A+ I A++ +L+ ++R +
Sbjct: 343 VHVIGAGAMGGDIAAWCAGQGLRVSLADMKAEPIAGAVKRAA-ELY----GKIIRKPTEV 397
Query: 310 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLD 435
+ + D V+ A V E VPE L+LK+KV+ L+
Sbjct: 398 RDALDRLIPDMD-GEGVRNADLVIEAVPEKLELKQKVYAGLE 438
>UniRef50_Q834J0 Cluster: Dihydrolipoyl dehydrogenase; n=3;
Lactobacillales|Rep: Dihydrolipoyl dehydrogenase -
Enterococcus faecalis (Streptococcus faecalis)
Length = 469
Score = 36.3 bits (80), Expect = 1.1
Identities = 19/56 (33%), Positives = 30/56 (53%), Gaps = 1/56 (1%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQL-HTLENDGL 288
E I I+G G+IG WA L S+G VT+ + + + + + I +L LE G+
Sbjct: 183 ESIAIIGGGVIGVEWASLLNSLGVNVTIIEFLDRLLINESATISKELKKRLEQRGI 238
>UniRef50_Q1IMR6 Cluster: UDP-glucose/GDP-mannose dehydrogenase;
n=33; Bacteria|Rep: UDP-glucose/GDP-mannose
dehydrogenase - Acidobacteria bacterium (strain
Ellin345)
Length = 448
Score = 36.3 bits (80), Expect = 1.1
Identities = 16/51 (31%), Positives = 32/51 (62%)
Frame = +1
Query: 79 GTVASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQI 231
GT+A+ + + + +IGIVG G +G A+LF+ ++VT +D+ +++
Sbjct: 6 GTLATELKRKIEAREARIGIVGMGYVGLPLALLFSEEKFRVTGFDIDNRKV 56
>UniRef50_Q121N3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=19;
Burkholderiales|Rep: 3-hydroxyisobutyrate dehydrogenase
- Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 298
Score = 36.3 bits (80), Expect = 1.1
Identities = 15/38 (39%), Positives = 23/38 (60%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAI 243
+G++G G +GR A S GY V VYDV A+ + + +
Sbjct: 6 VGVIGLGAMGRGIAQTLRSAGYAVHVYDVRAQAVQEFV 43
>UniRef50_Q11BV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Mesorhizobium sp. BNC1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Mesorhizobium sp. (strain BNC1)
Length = 677
Score = 36.3 bits (80), Expect = 1.1
Identities = 28/102 (27%), Positives = 49/102 (48%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 306
++G++G+G +G A+ + G V + D +T A +K L LE G L+
Sbjct: 287 RLGVIGAGTMGVGLAVSLLAAGKSVVLIDKDDLALTRASAAVKSGLARLERGGKLKEAPD 346
Query: 307 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNL 432
A+ + S +L +AV+ V E V E+ ++K V +L
Sbjct: 347 AA--LARLVASKEL-SAVENCEVVIEAVVESFEVKSAVLSDL 385
>UniRef50_Q041G8 Cluster: Acetoin/pyruvate dehydrogenase complex, E3
component, dihydrolipoamide dehydrogenase; n=3;
Lactobacillus|Rep: Acetoin/pyruvate dehydrogenase
complex, E3 component, dihydrolipoamide dehydrogenase -
Lactobacillus gasseri (strain ATCC 33323 / DSM 20243)
Length = 443
Score = 36.3 bits (80), Expect = 1.1
Identities = 20/54 (37%), Positives = 30/54 (55%)
Frame = +1
Query: 91 STVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDI 252
ST M K E + I+G+G IG +A +FA G +VTV D + ++ +DI
Sbjct: 149 STQAMDEKKMPENLTIIGAGYIGLEFASMFAKYGSKVTVLDHSREFLSREDDDI 202
>UniRef50_A3XHA5 Cluster: Regulatory protein; n=4;
Flavobacteriaceae|Rep: Regulatory protein -
Leeuwenhoekiella blandensis MED217
Length = 503
Score = 36.3 bits (80), Expect = 1.1
Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 4/71 (5%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLEND----GLL 291
E I +G+G IG +A + A G VT+ DV A+ +++ ED+ QL + L
Sbjct: 220 ESIIFIGAGYIGMEFAHIAARCGVDVTIVDVNARILSNFDEDLALQLQKKSEELGIKFLF 279
Query: 292 RGELKASEQFQ 324
E KA E+ +
Sbjct: 280 NAEAKAIEKLR 290
>UniRef50_A3M5D5 Cluster: Dihydrolipoamide dehydrogenase; n=1;
Acinetobacter baumannii ATCC 17978|Rep: Dihydrolipoamide
dehydrogenase - Acinetobacter baumannii (strain ATCC
17978 / NCDC KC 755)
Length = 279
Score = 36.3 bits (80), Expect = 1.1
Identities = 21/53 (39%), Positives = 32/53 (60%), Gaps = 2/53 (3%)
Frame = +1
Query: 136 IVGSGLIGRSWAMLFASVGYQVTVYDVVAKQI--TDAIEDIKYQLHTLENDGL 288
+VGSG IG +A L+ +G QVT+ D +AKQI T+ +E ++ E G+
Sbjct: 95 VVGSGAIGSEFASLYQDLGCQVTLID-LAKQILPTEDVEVAQFVRKQFEQKGM 146
>UniRef50_Q8U0F8 Cluster: NDP-sugar dehydrogenase; n=4;
Thermococcaceae|Rep: NDP-sugar dehydrogenase -
Pyrococcus furiosus
Length = 434
Score = 36.3 bits (80), Expect = 1.1
Identities = 18/43 (41%), Positives = 25/43 (58%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIK 255
KI ++G G IG A++FA GY+V +D V K + D I K
Sbjct: 18 KIAVIGLGYIGLPTAIMFAEAGYEVIGFD-VKKDVVDRINSGK 59
>UniRef50_O83080 Cluster: D-lactate dehydrogenase; n=1; Treponema
pallidum|Rep: D-lactate dehydrogenase - Treponema
pallidum
Length = 331
Score = 36.3 bits (80), Expect = 1.1
Identities = 15/38 (39%), Positives = 26/38 (68%)
Frame = +1
Query: 100 IMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYD 213
I++ + + ++GI+G+G IG++ A LF VG QV +D
Sbjct: 139 ILSKELRCSRVGILGTGRIGQAAARLFKGVGAQVVGFD 176
>UniRef50_P35484 Cluster: Dihydrolipoyl dehydrogenase; n=3;
Acholeplasmataceae|Rep: Dihydrolipoyl dehydrogenase -
Acholeplasma laidlawii
Length = 336
Score = 36.3 bits (80), Expect = 1.1
Identities = 27/98 (27%), Positives = 48/98 (48%), Gaps = 4/98 (4%)
Frame = +1
Query: 85 VASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKY-Q 261
V S ++ K + I IVG G+IG +A +F S G +VT+ +++ + +DI+
Sbjct: 161 VTSRELLNVKNYPKSIVIVGGGVIGVEFATVFNSFGSKVTIIEMMDGILPTMDDDIRVAY 220
Query: 262 LHTLENDG---LLRGELKASEQFQCIKGSTDLATAVKG 366
TL+ DG L + E+K + + T ++G
Sbjct: 221 AKTLKRDGIEILTKAEVKKVDDHKVTYSLDGKETTIEG 258
>UniRef50_Q892P7 Cluster: Dihydrolipoamide dehydrogenase; n=3;
Clostridia|Rep: Dihydrolipoamide dehydrogenase -
Clostridium tetani
Length = 589
Score = 35.9 bits (79), Expect = 1.4
Identities = 15/43 (34%), Positives = 28/43 (65%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDI 252
EKI I+G G+IG +A ++A++G +V+V + ++ ED+
Sbjct: 295 EKIAIIGGGVIGMEFAFIYANMGVEVSVIEYFDNILSMLDEDV 337
>UniRef50_Q67L77 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Symbiobacterium thermophilum
Length = 296
Score = 35.9 bits (79), Expect = 1.4
Identities = 30/104 (28%), Positives = 48/104 (46%), Gaps = 1/104 (0%)
Frame = +1
Query: 133 GIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQL-HTLENDGLLRGELKA 309
GIVG+G GR A L A+ G +V + +++ A + L H +E L + E +A
Sbjct: 7 GIVGTGPSGRGIAQLVATQGLEVIMVGRSEEELEQARRQLDLALQHEIEKWALTQSEKRA 66
Query: 310 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSV 441
I +TD+ K + V E + K++F+ LD V
Sbjct: 67 I--LARISMTTDINELAKADFVIATLVVEIAE-DKEIFRTLDQV 107
>UniRef50_Q2RJ81 Cluster: 4Fe-4S ferredoxin, iron-sulfur binding
precursor; n=1; Moorella thermoacetica ATCC 39073|Rep:
4Fe-4S ferredoxin, iron-sulfur binding precursor -
Moorella thermoacetica (strain ATCC 39073)
Length = 1487
Score = 35.9 bits (79), Expect = 1.4
Identities = 15/34 (44%), Positives = 22/34 (64%)
Frame = +1
Query: 118 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVV 219
+ EK+ I+G+G G + A A GYQVT+YD +
Sbjct: 255 RKEKVAIIGAGPAGLTAAQDLALAGYQVTIYDAL 288
>UniRef50_Q2GH13 Cluster: FAD-dependent oxidoreductase; n=6;
Anaplasmataceae|Rep: FAD-dependent oxidoreductase -
Ehrlichia chaffeensis (strain Arkansas)
Length = 354
Score = 35.9 bits (79), Expect = 1.4
Identities = 15/35 (42%), Positives = 24/35 (68%)
Frame = +1
Query: 121 SEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAK 225
++K G+VG+GL+GR A+ G+QVT++D K
Sbjct: 2 NKKAGVVGAGLVGRLLALRLLHDGWQVTLFDKFGK 36
>UniRef50_Q8GP50 Cluster: Eps11H; n=13; Lactobacillales|Rep: Eps11H
- Streptococcus thermophilus
Length = 416
Score = 35.9 bits (79), Expect = 1.4
Identities = 30/104 (28%), Positives = 49/104 (47%)
Frame = +1
Query: 112 KFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLL 291
+FK KI + G+G +G S A L S ++VT D+ I + +E I + ++++ +
Sbjct: 3 EFKDLKIAVAGTGYVGLSIATLL-SQHHKVTAVDI----IPEKVELINNKKSPIQDEYI- 56
Query: 292 RGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVF 423
E +E+ + + D A A FV P N D KK F
Sbjct: 57 --EKYLAEKELDLTATLDAKEAYSDADFVVIAAPTNYDSKKNFF 98
>UniRef50_Q6RK69 Cluster: D-lactate dehydrogenase; n=1;
Lactobacillus sp. MD-1|Rep: D-lactate dehydrogenase -
Lactobacillus sp. MD-1
Length = 331
Score = 35.9 bits (79), Expect = 1.4
Identities = 16/48 (33%), Positives = 24/48 (50%)
Frame = +1
Query: 91 STVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQIT 234
S M + +G++G+G IGR LF +G V YD ++IT
Sbjct: 136 SPAFMGRLISEQTVGVIGTGRIGRHAIQLFRGLGANVIAYDKYPQKIT 183
>UniRef50_Q0SEV8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=34;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 298
Score = 35.9 bits (79), Expect = 1.4
Identities = 29/114 (25%), Positives = 56/114 (49%), Gaps = 3/114 (2%)
Frame = +1
Query: 118 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRG 297
K +++G++G+G++G A + A V V++ + I L +L+ G+ G
Sbjct: 5 KIQRVGVIGAGIMGAGIAEVCARAHVDVLVFEQTRELAAAGRSRI---LRSLDR-GVSSG 60
Query: 298 ELKASEQFQC---IKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDD 450
++ E+ Q ++ ++DL + V E V E+ +K ++F LD VV D
Sbjct: 61 KITEREREQAAWRLRFTSDLGDFADRQLVV-EAVVEDEKVKSEIFTELDQVVTD 113
>UniRef50_A7BC28 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 455
Score = 35.9 bits (79), Expect = 1.4
Identities = 20/55 (36%), Positives = 35/55 (63%)
Frame = +1
Query: 85 VASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIED 249
V ST I++ ++ I+G G+IG +A L+A++G QVTV + +A +I ++D
Sbjct: 158 VDSTGILSLPQIPARLAIIGGGVIGVEFASLYATLGSQVTVIE-MAPEILPFMDD 211
>UniRef50_A6VXM3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase catalytic region; n=2; Marinomonas|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
region - Marinomonas sp. MWYL1
Length = 380
Score = 35.9 bits (79), Expect = 1.4
Identities = 15/36 (41%), Positives = 26/36 (72%)
Frame = +1
Query: 121 SEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQ 228
S+KIG++G G +G++ FA++G QV VYD + ++
Sbjct: 116 SKKIGVIGYGNVGKTVYTRFANMGCQVHVYDPIREK 151
>UniRef50_A6LMV1 Cluster: Putative uncharacterized protein
precursor; n=1; Thermosipho melanesiensis BI429|Rep:
Putative uncharacterized protein precursor - Thermosipho
melanesiensis BI429
Length = 208
Score = 35.9 bits (79), Expect = 1.4
Identities = 21/44 (47%), Positives = 29/44 (65%), Gaps = 2/44 (4%)
Frame = +1
Query: 112 KFKSEK-IGIVGSGLIGRSWAMLFASVGYQVTV-YDVVAKQITD 237
K KS+K IGI G+GL+GR+ A L + G+ V V +D K+I D
Sbjct: 109 KLKSKKNIGIYGAGLVGRALAQLLLNRGFNVVVFFDDDEKKIGD 152
>UniRef50_A4BGI3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Reinekea sp. MED297|Rep: 3-hydroxyacyl-CoA dehydrogenase
- Reinekea sp. MED297
Length = 705
Score = 35.9 bits (79), Expect = 1.4
Identities = 34/113 (30%), Positives = 48/113 (42%), Gaps = 2/113 (1%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 306
+IG+VG+G++G A AS G V + D + E K L RG L
Sbjct: 315 RIGVVGAGMMGAGIAWACASKGLPVVLVDTEQSR----AEQGKGYSERLVAKRFERGRLS 370
Query: 307 ASEQFQCIK--GSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
A E + T+ + + V E V E+ LK V+Q + SVV TI
Sbjct: 371 AEEGTALLNRITPTESMSELAECDLVIEAVFEDRALKADVYQLIQSVVSPETI 423
>UniRef50_A3ZZK1 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1;
Blastopirellula marina DSM 3645|Rep:
3-hydroxybutyryl-coA dehydrogenase - Blastopirellula
marina DSM 3645
Length = 319
Score = 35.9 bits (79), Expect = 1.4
Identities = 15/53 (28%), Positives = 28/53 (52%)
Frame = +2
Query: 575 EIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRL 733
EI+ T A + ++G+ P + R++ GF++NR+ YA+ E + L
Sbjct: 152 EIIRGEHTDDATADSAANLGRQLGKDPTIVQRDVPGFIVNRLAYAMYREAFWL 204
>UniRef50_A3XPY3 Cluster: Putative uncharacterized protein; n=1;
Leeuwenhoekiella blandensis MED217|Rep: Putative
uncharacterized protein - Leeuwenhoekiella blandensis
MED217
Length = 262
Score = 35.9 bits (79), Expect = 1.4
Identities = 17/39 (43%), Positives = 24/39 (61%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAI 243
KIGI+G+GLIG++ A F + G+QV + D D I
Sbjct: 2 KIGIIGAGLIGKTLAKKFNAAGHQVKLGDAKGAASIDTI 40
>UniRef50_A0W3T3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Geobacter lovleyi SZ|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor - Geobacter
lovleyi SZ
Length = 285
Score = 35.9 bits (79), Expect = 1.4
Identities = 20/57 (35%), Positives = 29/57 (50%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGE 300
IG+ G+G +G A L A G++V +Y A + DA I+ L L GL+ E
Sbjct: 8 IGVAGAGSMGAGIAQLAAMAGFRVRLYARHASALADAAGRIETSLAKLHEKGLIGEE 64
>UniRef50_A3LNF8 Cluster: Kynurenine 3-monooxygenase, mitochondrial;
n=3; Saccharomycetaceae|Rep: Kynurenine 3-monooxygenase,
mitochondrial - Pichia stipitis (Yeast)
Length = 478
Score = 35.9 bits (79), Expect = 1.4
Identities = 14/33 (42%), Positives = 25/33 (75%)
Frame = +1
Query: 118 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDV 216
+ + +GIVG+GL+G A+ FA+ GY VT++++
Sbjct: 12 RHQGVGIVGAGLVGCLAALAFAAKGYSVTLFEL 44
>UniRef50_UPI00006A2AB5 Cluster: UPI00006A2AB5 related cluster; n=2;
Xenopus tropicalis|Rep: UPI00006A2AB5 UniRef100 entry -
Xenopus tropicalis
Length = 597
Score = 35.5 bits (78), Expect = 1.8
Identities = 17/56 (30%), Positives = 34/56 (60%), Gaps = 1/56 (1%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQL-HTLENDGL 288
+++ I+G+G IG +A + +VG +V V ++ + + EDI Q+ +L+ DG+
Sbjct: 319 QRLLIIGAGAIGIEFASFYRAVGSEVAVVEMAPRVLPQEDEDISAQVAASLQKDGI 374
>UniRef50_Q8FX64 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=10; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Brucella suis
Length = 509
Score = 35.5 bits (78), Expect = 1.8
Identities = 29/112 (25%), Positives = 47/112 (41%), Gaps = 2/112 (1%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGE--L 303
I IVG+G++G A + A G ++D + + + L L G + E
Sbjct: 8 IAIVGAGVMGTGIAQIAAQAGLVTQIFDAREGAAAASRDRLASTLAKLAEKGKISAEDAQ 67
Query: 304 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
A + + +LA V E + E LD K+ +F L++VV N I
Sbjct: 68 TAVSRIEICSSIQELA----DCDLVVEAIVEKLDAKQALFLELEAVVSGNCI 115
>UniRef50_Q5NW50 Cluster: DitN-like 3-hydroxyacyl-CoA
dehydrogenase,possibly related to diterpenoid
metabolism; n=6; Proteobacteria|Rep: DitN-like
3-hydroxyacyl-CoA dehydrogenase,possibly related to
diterpenoid metabolism - Azoarcus sp. (strain EbN1)
(Aromatoleum aromaticum (strain EbN1))
Length = 299
Score = 35.5 bits (78), Expect = 1.8
Identities = 27/115 (23%), Positives = 51/115 (44%), Gaps = 3/115 (2%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 303
EKI +VG+GL+G A A GY++ + D + A+ Q+++L G+ G+L
Sbjct: 5 EKIIVVGAGLMGTGIAYSCAISGYRILLVDANPSALDKAVG----QINSLVAAGVKLGKL 60
Query: 304 ---KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
+ ++ + +L A + E E +D+K + D ++ I
Sbjct: 61 VEAAGKAALERLEAAIELDGRASDAALLIETATEKIDIKLAIIGKADELLPPEAI 115
>UniRef50_Q3AEV2 Cluster: Prephenate dehydrogenase; n=1;
Carboxydothermus hydrogenoformans Z-2901|Rep: Prephenate
dehydrogenase - Carboxydothermus hydrogenoformans
(strain Z-2901 / DSM 6008)
Length = 360
Score = 35.5 bits (78), Expect = 1.8
Identities = 18/35 (51%), Positives = 23/35 (65%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQI 231
KIGIVG GLIG S A F+ +GYQV D ++ +
Sbjct: 4 KIGIVGLGLIGGSLARAFSYLGYQVYGIDTNSQYV 38
>UniRef50_Q3IBS8 Cluster: Iron-sulfur-binding protein, glutamate
synthase subunit; n=3; uncultured sulfate-reducing
bacterium|Rep: Iron-sulfur-binding protein, glutamate
synthase subunit - uncultured sulfate-reducing bacterium
Length = 576
Score = 35.5 bits (78), Expect = 1.8
Identities = 17/36 (47%), Positives = 22/36 (61%)
Frame = +1
Query: 118 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAK 225
K EKI ++G+G G S A A GY VTVY+ + K
Sbjct: 139 KDEKIAVIGAGPSGMSCAYQLARRGYPVTVYESLPK 174
>UniRef50_Q1YTH7 Cluster: Fatty oxidation complex, alpha subunit;
n=4; Gammaproteobacteria|Rep: Fatty oxidation complex,
alpha subunit - gamma proteobacterium HTCC2207
Length = 718
Score = 35.5 bits (78), Expect = 1.8
Identities = 32/120 (26%), Positives = 56/120 (46%), Gaps = 1/120 (0%)
Frame = +1
Query: 103 MASKFKSEKI-GIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLEN 279
+ASK K G++G+G++G A A GY V + D+ + I++ L
Sbjct: 310 LASKLPEIKTAGVIGAGIMGGGIAYQNAIRGYSVVMKDINQPALDLGIQEANKLLAKGVK 369
Query: 280 DGLLRGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
G L E KA + IK S + + + V E V E +KK V +++++D++ +
Sbjct: 370 RGKLTEE-KAGQILSLIKPSLEDSDVAPCNMLV-EAVVELESVKKMVLPAVEALLDNSAV 427
>UniRef50_Q1IUZ3 Cluster: UDP-glucose/GDP-mannose dehydrogenase;
n=1; Acidobacteria bacterium Ellin345|Rep:
UDP-glucose/GDP-mannose dehydrogenase - Acidobacteria
bacterium (strain Ellin345)
Length = 422
Score = 35.5 bits (78), Expect = 1.8
Identities = 22/94 (23%), Positives = 45/94 (47%), Gaps = 2/94 (2%)
Frame = +1
Query: 130 IGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELKA 309
+G+ GSG +G + A +G VT YD + D+ + + H ++R ++A
Sbjct: 3 VGVYGSGYLGTVVSACLADLGMPVTCYDADTTLVMDSAQG-TLRFHEKNLKEIVRRNVRA 61
Query: 310 SEQFQCIKGSTDLATAVK--GAVFVQECVPENLD 405
+ +T+L + + GA+F+ E P+ ++
Sbjct: 62 DR----LMYTTELESVARRAGAIFIAEDTPDEIE 91
>UniRef50_Q0F8T2 Cluster: Salicylate hydroxylase; n=1; alpha
proteobacterium HTCC2255|Rep: Salicylate hydroxylase -
alpha proteobacterium HTCC2255
Length = 386
Score = 35.5 bits (78), Expect = 1.8
Identities = 20/65 (30%), Positives = 37/65 (56%), Gaps = 2/65 (3%)
Frame = +1
Query: 121 SEKIGIVGSGLIGRSWAMLFASVGYQVTVYD--VVAKQITDAIEDIKYQLHTLENDGLLR 294
++KIG++G G+ G + A+ FA G QVT+Y+ +V ++ I+ ++ L G+
Sbjct: 5 NKKIGVIGGGIGGLASAIAFAKFGSQVTLYEKALVISEVGAGIQISANGINVLTKLGIYP 64
Query: 295 GELKA 309
LK+
Sbjct: 65 DYLKS 69
>UniRef50_Q0B0P7 Cluster: NADP oxidoreductase, coenzyme
F420-dependent; n=1; Syntrophomonas wolfei subsp. wolfei
str. Goettingen|Rep: NADP oxidoreductase, coenzyme
F420-dependent - Syntrophomonas wolfei subsp. wolfei
(strain Goettingen)
Length = 298
Score = 35.5 bits (78), Expect = 1.8
Identities = 15/44 (34%), Positives = 29/44 (65%), Gaps = 1/44 (2%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVT-VYDVVAKQITDAIEDI 252
EKIGI+G+G++G + ++ + GY++T V D+ ++ +E I
Sbjct: 3 EKIGIIGAGVVGTAVGVVLKNKGYEITGVQDIKSESTQQLVERI 46
>UniRef50_A6WDS7 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=1; Kineococcus radiotolerans
SRS30216|Rep: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding - Kineococcus radiotolerans SRS30216
Length = 681
Score = 35.5 bits (78), Expect = 1.8
Identities = 31/142 (21%), Positives = 61/142 (42%), Gaps = 1/142 (0%)
Frame = +1
Query: 118 KSEKIGIVGSGLIGRSWAMLFA-SVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLR 294
K +G+VG+GL+ A+L + V + DV ++ + ++ + L G +
Sbjct: 317 KVTSVGVVGAGLMASQLALLLLHRLQVPVVLTDVSPDRVEKGVGFVREGVAELLRKGRVS 376
Query: 295 GELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXX 474
+ A+ + GS D +A+ A FV E V E L +K+ V + L+ ++ + +
Sbjct: 377 PD-TANRLSASVSGSVD-KSALADADFVVEAVFEELAVKQDVLRELEPLLRPDAVIATNT 434
Query: 475 XXXXXXXXXEGLKHKSQVIVSH 540
L+H + + H
Sbjct: 435 SSLSVTAMASVLEHPQRFVGFH 456
>UniRef50_A3DJQ8 Cluster: NADH:flavin oxidoreductase/NADH oxidase;
n=1; Clostridium thermocellum ATCC 27405|Rep:
NADH:flavin oxidoreductase/NADH oxidase - Clostridium
thermocellum (strain ATCC 27405 / DSM 1237)
Length = 645
Score = 35.5 bits (78), Expect = 1.8
Identities = 22/79 (27%), Positives = 41/79 (51%), Gaps = 2/79 (2%)
Frame = +1
Query: 85 VASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQ- 261
+A+ ++ + + + IVG GL+G + A G +VT+ D++ + D I ++
Sbjct: 495 IATKLLKEGQDTGQNVIIVGGGLVGCETGLHLAEKGKKVTIIDMLPEVAQDVIFMARFSL 554
Query: 262 LHTLENDGL-LRGELKASE 315
L L+N G+ G LK +E
Sbjct: 555 LEALKNKGIETYGGLKLTE 573
>UniRef50_Q0V6D4 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 508
Score = 35.5 bits (78), Expect = 1.8
Identities = 18/42 (42%), Positives = 27/42 (64%)
Frame = +1
Query: 118 KSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAI 243
K EKI ++G G +G A+LFA VG V++ D ++Q DA+
Sbjct: 3 KFEKIAMIGCGSMGGGMALLFAEVGVHVSLSD-PSEQAMDAV 43
>UniRef50_Q97HK2 Cluster: 3-Hydroxyacyl-CoA dehydrogenase; n=1;
Clostridium acetobutylicum|Rep: 3-Hydroxyacyl-CoA
dehydrogenase - Clostridium acetobutylicum
Length = 379
Score = 35.1 bits (77), Expect = 2.4
Identities = 28/111 (25%), Positives = 51/111 (45%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 306
+IGI+G G +GR + Y+V + A+Q+ + I+ QL L+ E
Sbjct: 2 EIGIIGKGKMGRDIFNYISMFDYKVILICRQAEQVEEVKSSIEKQLRKKLKRNLITEEEY 61
Query: 307 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
S++ K TD +K + E + E+ LK+ + +++ +V D I
Sbjct: 62 NSKK-DAYK-VTDNIQDLKNCDIIIEAIYEDEVLKQNILGDVEKIVKDECI 110
>UniRef50_Q62DG4 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=48; Bacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Burkholderia mallei
(Pseudomonas mallei)
Length = 331
Score = 35.1 bits (77), Expect = 2.4
Identities = 29/119 (24%), Positives = 44/119 (36%)
Frame = +1
Query: 103 MASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLEND 282
MA K + +G+G+IG W + G V +D +++ LE
Sbjct: 11 MAVITKIDTFAAIGAGVIGSGWVARALANGLDVLAWDPAEDAEMQLRANVENAWPALERA 70
Query: 283 GLLRGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
GL G A F + V A FVQE PE LK ++ + + + I
Sbjct: 71 GLAPGASPARLHFV-----PTIEACVADADFVQESAPEREALKLELHERISRAAKPDAI 124
>UniRef50_Q485S6 Cluster: Putative D-amino acid dehydrogenase, small
subunit; n=1; Colwellia psychrerythraea 34H|Rep:
Putative D-amino acid dehydrogenase, small subunit -
Colwellia psychrerythraea (strain 34H / ATCC BAA-681)
(Vibriopsychroerythus)
Length = 427
Score = 35.1 bits (77), Expect = 2.4
Identities = 16/42 (38%), Positives = 27/42 (64%), Gaps = 1/42 (2%)
Frame = +1
Query: 91 STVI-MASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYD 213
STV+ K + + ++G+G+IG + A+ S+GYQVT+ D
Sbjct: 2 STVVDQEGNNKQQTVAVIGAGIIGINCALELQSLGYQVTLLD 43
>UniRef50_Q28N18 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=23; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding - Jannaschia
sp. (strain CCS1)
Length = 733
Score = 35.1 bits (77), Expect = 2.4
Identities = 30/119 (25%), Positives = 53/119 (44%), Gaps = 8/119 (6%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVV------AKQITDAIED--IKYQLHTLEN 279
+K+GI+G+G++G A + A G +V + D K ++ + D +K T E
Sbjct: 328 KKVGIIGAGMMGAGIAYVSALAGIEVVLIDAAQDSADRGKAYSEGLLDKGMKRGKVTEEK 387
Query: 280 DGLLRGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNT 456
+ G++ A+ + + G DL + AVF V + K + N D + NT
Sbjct: 388 KAKVLGQITATTDYDALNG-CDL---IVEAVFEDPKVKAEVTAKAEAAMNADGIFATNT 442
>UniRef50_Q1NHB4 Cluster: Fatty oxidation complex, alpha subunit;
n=2; Proteobacteria|Rep: Fatty oxidation complex, alpha
subunit - Sphingomonas sp. SKA58
Length = 722
Score = 35.1 bits (77), Expect = 2.4
Identities = 29/116 (25%), Positives = 52/116 (44%)
Frame = +1
Query: 112 KFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLL 291
KF+++K+G++G+G++G A + A+ G V + D + L L G L
Sbjct: 310 KFEAKKVGVLGAGMMGAGIAFVSANAGIDVVLIDRDTATAQKGKDYSAKVLGKLVEKGKL 369
Query: 292 RGELKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
+ KA I + D A + G V E V E+ +K + + ++V+ I
Sbjct: 370 TQD-KADAVLARITPTDDFA-LLDGCDMVVEAVFEDTAIKAETTKKAEAVLPAQAI 423
>UniRef50_Q05FN5 Cluster: Dihydrodipicolinate synthase; n=1;
Candidatus Carsonella ruddii PV|Rep: Dihydrodipicolinate
synthase - Carsonella ruddii (strain PV)
Length = 254
Score = 35.1 bits (77), Expect = 2.4
Identities = 18/45 (40%), Positives = 28/45 (62%), Gaps = 2/45 (4%)
Frame = -1
Query: 799 LXSKSFRH-NFINIRYINNFVVNETPNFIKDCVL-NSIQNKSVYF 671
L K F++ NI++I NF++N+ P FIK + NS+ N +YF
Sbjct: 197 LLPKYFKYIKTFNIQFIKNFILNKNPIFIKYILFKNSLINNLIYF 241
>UniRef50_A5IXT8 Cluster: D-lactate dehydrogenase; n=3;
Mycoplasma|Rep: D-lactate dehydrogenase - Mycoplasma
agalactiae
Length = 329
Score = 35.1 bits (77), Expect = 2.4
Identities = 19/48 (39%), Positives = 29/48 (60%), Gaps = 1/48 (2%)
Frame = +1
Query: 106 ASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVA-KQITDAIE 246
A + +S + I+G+G IG A +F S G +V YD++ K +TD IE
Sbjct: 141 AKELRSSTVLIMGTGKIGYESAKMFKSFGAKVLGYDLMPNKALTDVIE 188
>UniRef50_P77212 Cluster: Probable pyridine nucleotide-disulfide
oxidoreductase ykgC; n=17; Enterobacteriaceae|Rep:
Probable pyridine nucleotide-disulfide oxidoreductase
ykgC - Escherichia coli (strain K12)
Length = 441
Score = 35.1 bits (77), Expect = 2.4
Identities = 20/68 (29%), Positives = 34/68 (50%)
Frame = +1
Query: 79 GTVASTVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKY 258
G ST ++ K +GI+G G IG +A +FA+ G +VT+ + + + DI
Sbjct: 144 GVYDSTGLLNLKELPGHLGILGGGYIGVEFASMFANFGSKVTILEAASLFLPREDRDIAD 203
Query: 259 QLHTLEND 282
+ T+ D
Sbjct: 204 NIATILRD 211
>UniRef50_P53267 Cluster: DASH complex subunit DAM1; n=2;
Saccharomyces cerevisiae|Rep: DASH complex subunit DAM1
- Saccharomyces cerevisiae (Baker's yeast)
Length = 343
Score = 35.1 bits (77), Expect = 2.4
Identities = 26/105 (24%), Positives = 50/105 (47%)
Frame = +1
Query: 121 SEKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGE 300
+E +G + G++ SW + F+ + + D++A + ++ED K L +E + RG
Sbjct: 95 NESLGSLLYGIMSNSWCVEFSQAPHDIQ-DDLIAIKQLKSLEDEKNNL-VMELSNMERGI 152
Query: 301 LKASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLD 435
+ ++ +G DLA A + F Q P + K + + N D
Sbjct: 153 KRKKDE----QGENDLAKASQNKQFNQPLFPSSQVRKYRSYDNRD 193
>UniRef50_Q8E285 Cluster: Pyridine nucleotide-disulphide
oxidoreductase family protein; n=17; Streptococcus|Rep:
Pyridine nucleotide-disulphide oxidoreductase family
protein - Streptococcus agalactiae serotype V
Length = 439
Score = 34.7 bits (76), Expect = 3.2
Identities = 16/41 (39%), Positives = 25/41 (60%)
Frame = +1
Query: 91 STVIMASKFKSEKIGIVGSGLIGRSWAMLFASVGYQVTVYD 213
ST I +++GI+G G IG +A L++ +G +VTV D
Sbjct: 148 STAIQELAHLPKRLGIIGGGNIGLEFATLYSELGSKVTVID 188
>UniRef50_Q83EI9 Cluster: Thiamine biosynthesis oxidoreductase ThiO,
putative; n=7; Legionellales|Rep: Thiamine biosynthesis
oxidoreductase ThiO, putative - Coxiella burnetii
Length = 338
Score = 34.7 bits (76), Expect = 3.2
Identities = 14/29 (48%), Positives = 21/29 (72%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYD 213
K+GI G+GL+GR A + VG+ VT++D
Sbjct: 2 KVGIAGAGLLGRLLAWQLSKVGFGVTLFD 30
>UniRef50_Q7WIS8 Cluster: Putative enoyl-CoA isomerase; n=2;
Bordetella|Rep: Putative enoyl-CoA isomerase -
Bordetella bronchiseptica (Alcaligenes bronchisepticus)
Length = 694
Score = 34.7 bits (76), Expect = 3.2
Identities = 27/112 (24%), Positives = 46/112 (41%)
Frame = +1
Query: 124 EKIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGEL 303
E++ +VG+G +G + A G V +DV A ++ + L L
Sbjct: 288 EQVAVVGAGTMGTGIVICLADAGLPVIWHDVDADRLAQGRAQVCQHFERLAARKRLTS-- 345
Query: 304 KASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVFQNLDSVVDDNTI 459
+ +EQ +T + A E V E++ +K VF+ LD V+ I
Sbjct: 346 RQAEQRVAAVATTGEMAGIAQADLAIEAVFEDMAVKCAVFRELDRVLKPGAI 397
>UniRef50_Q7NCM9 Cluster: Glr2949 protein; n=1; Gloeobacter
violaceus|Rep: Glr2949 protein - Gloeobacter violaceus
Length = 1044
Score = 34.7 bits (76), Expect = 3.2
Identities = 15/45 (33%), Positives = 28/45 (62%), Gaps = 1/45 (2%)
Frame = +1
Query: 310 SEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVF-QNLDSV 441
++ FQCIKGS + ++ +V++ +P LD ++ + Q +DSV
Sbjct: 410 TKAFQCIKGSNNFFATLENEDYVRQAIPHFLDYSRRQYGQAIDSV 454
>UniRef50_Q6AA68 Cluster: UDP-glucose 6-dehydrogenase; n=3;
root|Rep: UDP-glucose 6-dehydrogenase -
Propionibacterium acnes
Length = 388
Score = 34.7 bits (76), Expect = 3.2
Identities = 32/109 (29%), Positives = 51/109 (46%), Gaps = 2/109 (1%)
Frame = +1
Query: 127 KIGIVGSGLIGRSWAMLFASVGYQVTVYDVVAKQITDAIEDIKYQLHTLENDGLLRGELK 306
KI + G G +G + A+L A V + D+ A+++ D+ HT D L+ E
Sbjct: 2 KIAVAGLGYVGMANAVLLAQHNSVVAI-DIDAERV-----DMVNNRHTTIVDPLI-AEYL 54
Query: 307 ASEQFQCIKGSTDLATAVKGAVFVQECVPENLDLKKKVF--QNLDSVVD 447
A ++ +TD A +GA FV P N D + F ++D V+D
Sbjct: 55 AHHNLD-LRATTDPQEAYRGADFVVIATPTNYDPGQNYFDTSSVDEVLD 102
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 840,660,861
Number of Sequences: 1657284
Number of extensions: 16667705
Number of successful extensions: 48498
Number of sequences better than 10.0: 321
Number of HSP's better than 10.0 without gapping: 46393
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 48406
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 80751996367
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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